Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 26108
• Symbol: PYGO1
• Description: pygopus family PHD finger 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PYGO1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
55588826	55588849	15	+	26472758	Jiyoye	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	1.9672632135880002	[38]	[114]	8	hSpCas9	negative selection	131785
55546348	55546371	15	-	26472758	Jiyoye	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.5115120413206091	[39]	[42]	4	hSpCas9	negative selection	131786
55548974	55548997	15	-	26472758	Jiyoye	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	1.1254044130904939	[92]	[152]	7	hSpCas9	negative selection	131787
55548909	55548932	15	-	26472758	Jiyoye	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.7405991152310654	[49]	[62]	5	hSpCas9	negative selection	131788
55588812	55588835	15	+	26472758	Jiyoye	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.09114788805819543	[121]	[97]	0	hSpCas9	negative selection	131789
55548947	55548970	15	-	26472758	Jiyoye	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	-0.06478918585780602	[447]	[322]	0	hSpCas9	negative selection	131790
55588790	55588813	15	+	26472758	Jiyoye	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.6475343493717703	[170]	[201]	5	hSpCas9	negative selection	131791
55548959	55548982	15	-	26472758	Jiyoye	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	2.023846741954368	[29]	[91]	8	hSpCas9	negative selection	131792
55547113	55547136	15	+	26472758	Jiyoye	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	-0.5811428134464911	[122]	[61]	-4	hSpCas9	negative selection	131793
55546503	55546526	15	+	26472758	Jiyoye	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.30529576748665965	[131]	[122]	2	hSpCas9	negative selection	131794
55588826	55588849	15	+	26472758	KBM7	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.08936020706946479	[364,232]	[138,153]	0	hSpCas9	negative selection	322903
55546348	55546371	15	-	26472758	KBM7	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.25583264548529017	[293,339]	[214,148]	2	hSpCas9	negative selection	322904
55548974	55548997	15	-	26472758	KBM7	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.6147796097718186	[655,502]	[410,415]	6	hSpCas9	negative selection	322905
55548909	55548932	15	-	26472758	KBM7	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.49919884183342483	[371,449]	[162,116]	-4	hSpCas9	negative selection	322906
55588812	55588835	15	+	26472758	KBM7	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.1342883063343225	[646,249]	[257,189]	1	hSpCas9	negative selection	322907
55548947	55548970	15	-	26472758	KBM7	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	-0.21453954541286135	[1686,1128]	[622,506]	-2	hSpCas9	negative selection	322908
55588790	55588813	15	+	26472758	KBM7	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.6047617744662348	[1416,1397]	[970,1045]	6	hSpCas9	negative selection	322909
55548959	55548982	15	-	26472758	KBM7	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.600795864524073	[339,361]	[255,248]	6	hSpCas9	negative selection	322910
55547113	55547136	15	+	26472758	KBM7	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.458324213292635	[507,254]	[195,277]	5	hSpCas9	negative selection	322911
55546503	55546526	15	+	26472758	KBM7	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.39611731264222044	[504,522]	[203,423]	4	hSpCas9	negative selection	322912
55588826	55588849	15	+	26472758	Raji	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.9271048410116912	[253]	[30]	-6	hSpCas9	negative selection	514021
55546348	55546371	15	-	26472758	Raji	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	1.0030468755588637	[128]	[59]	8	hSpCas9	negative selection	514022
55548974	55548997	15	-	26472758	Raji	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.7176127947051856	[282]	[107]	6	hSpCas9	negative selection	514023
55548909	55548932	15	-	26472758	Raji	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.8729182817365764	[119]	[50]	7	hSpCas9	negative selection	514024
55588812	55588835	15	+	26472758	Raji	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.9481849405243457	[200]	[89]	8	hSpCas9	negative selection	514025
55548947	55548970	15	-	26472758	Raji	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.11399635844525258	[652]	[163]	1	hSpCas9	negative selection	514026
55588790	55588813	15	+	26472758	Raji	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	-0.013017560685621765	[586]	[134]	0	hSpCas9	negative selection	514027
55548959	55548982	15	-	26472758	Raji	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.07273723317460146	[212]	[46]	0	hSpCas9	negative selection	514028
55547113	55547136	15	+	26472758	Raji	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	-0.1821230818213853	[219]	[44]	-1	hSpCas9	negative selection	514029
55546503	55546526	15	+	26472758	Raji	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.33066023196965866	[232]	[67]	3	hSpCas9	negative selection	514030
55588826	55588849	15	+	26472758	K562	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.6155128793576936	[299]	[387]	5	hSpCas9	negative selection	705139
55546348	55546371	15	-	26472758	K562	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.36563475401753964	[260]	[170]	-2	hSpCas9	negative selection	705140
55548974	55548997	15	-	26472758	K562	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.9327798921705893	[488]	[787]	7	hSpCas9	negative selection	705141
55548909	55548932	15	-	26472758	K562	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.0625590257549441	[239]	[193]	0	hSpCas9	negative selection	705142
55588812	55588835	15	+	26472758	K562	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.10962194962773633	[425]	[387]	0	hSpCas9	negative selection	705143
55548947	55548970	15	-	26472758	K562	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	1.0871411996806066	[1156]	[2074]	8	hSpCas9	negative selection	705144
55588790	55588813	15	+	26472758	K562	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.31006676990196036	[1073]	[1123]	2	hSpCas9	negative selection	705145
55548959	55548982	15	-	26472758	K562	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.1151236590206933	[339]	[264]	-1	hSpCas9	negative selection	705146
55547113	55547136	15	+	26472758	K562	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.6676301583909909	[219]	[294]	5	hSpCas9	negative selection	705147
55546503	55546526	15	+	26472758	K562	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.038574151969191894	[548]	[475]	0	hSpCas9	negative selection	705148
55546262	55546285	15	+	26627737	DLD1	viability	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.18291067138093586	[583]	[184,185,118]	-2	hSpCas9	negative selection	791064
55546984	55547007	15	+	26627737	DLD1	viability	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.5517955666288574	[603]	[194,506,156]	5	hSpCas9	negative selection	791065
55548909	55548932	15	-	26627737	DLD1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.5996848673989057	[548]	[221,305,254]	6	hSpCas9	negative selection	791066
55548941	55548964	15	+	26627737	DLD1	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.9975228958013107	[173]	[100,138,89]	8	hSpCas9	negative selection	791067
55587836	55587859	15	+	26627737	DLD1	viability	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.5996067936285978	[1013]	[339,641,467]	6	hSpCas9	negative selection	791068
55588812	55588835	15	+	26627737	DLD1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.9241089261945619	[48]	[59,36,73]	9	hSpCas9	negative selection	791069
55546262	55546285	15	+	26627737	GBM cells	viability after 5 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.236465494233554	[348]	[227,212]	3	hSpCas9	negative selection	873379
55546984	55547007	15	+	26627737	GBM cells	viability after 5 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.9280149942864517	[318]	[310,339]	9	hSpCas9	negative selection	873380
55548909	55548932	15	-	26627737	GBM cells	viability after 5 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.14610400265470092	[411]	[174,313]	2	hSpCas9	negative selection	873381
55548941	55548964	15	+	26627737	GBM cells	viability after 5 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.028677629586264075	[135]	[68,73]	0	hSpCas9	negative selection	873382
55587836	55587859	15	+	26627737	GBM cells	viability after 5 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.4522667690900197	[645]	[492,454]	6	hSpCas9	negative selection	873383
55588812	55588835	15	+	26627737	GBM cells	viability after 5 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.9490830316692644	[80]	[4,39]	-9	hSpCas9	negative selection	873384
55546262	55546285	15	+	26627737	GBM cells	viability after 13 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.3674952125432508	[348]	[283,211]	5	hSpCas9	negative selection	955694
55546984	55547007	15	+	26627737	GBM cells	viability after 13 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.6305025976820084	[318]	[230,297]	7	hSpCas9	negative selection	955695
55548909	55548932	15	-	26627737	GBM cells	viability after 13 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.4666879419563402	[411]	[357,268]	6	hSpCas9	negative selection	955696
55548941	55548964	15	+	26627737	GBM cells	viability after 13 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.4425219106167727	[135]	[107,93]	5	hSpCas9	negative selection	955697
55587836	55587859	15	+	26627737	GBM cells	viability after 13 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.6433891719785731	[645]	[627,481]	7	hSpCas9	negative selection	955698
55588812	55588835	15	+	26627737	GBM cells	viability after 13 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.7362455456372552	[80]	[32,20]	-7	hSpCas9	negative selection	955699
55546262	55546285	15	+	26627737	GBM cells	viability after 21 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.4460539066366441	[348]	[262,253]	4	hSpCas9	negative selection	1038009
55546984	55547007	15	+	26627737	GBM cells	viability after 21 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.8717158529300184	[318]	[325,308]	8	hSpCas9	negative selection	1038010
55548909	55548932	15	-	26627737	GBM cells	viability after 21 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.9078256158785262	[411]	[420,418]	8	hSpCas9	negative selection	1038011
55548941	55548964	15	+	26627737	GBM cells	viability after 21 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.5951392080727983	[135]	[50,46]	-5	hSpCas9	negative selection	1038012
55587836	55587859	15	+	26627737	GBM cells	viability after 21 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.1066400241660057	[645]	[772,739]	9	hSpCas9	negative selection	1038013
55588812	55588835	15	+	26627737	GBM cells	viability after 21 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-2.282584815332394	[80]	[7,9]	-9	hSpCas9	negative selection	1038014
55546262	55546285	15	+	26627737	RPE1	viability after 9 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.07075243347854915	[871]	[363,186]	0	hSpCas9	negative selection	1120324
55546984	55547007	15	+	26627737	RPE1	viability after 9 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.37686338152294563	[1805]	[458,404]	-3	hSpCas9	negative selection	1120325
55548909	55548932	15	-	26627737	RPE1	viability after 9 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.0023144987765569836	[1304]	[389,433]	0	hSpCas9	negative selection	1120326
55548941	55548964	15	+	26627737	RPE1	viability after 9 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.14463031535300627	[826]	[183,298]	-1	hSpCas9	negative selection	1120327
55587836	55587859	15	+	26627737	RPE1	viability after 9 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.2154571262984337	[1962]	[1251,1652]	7	hSpCas9	negative selection	1120328
55588812	55588835	15	+	26627737	RPE1	viability after 9 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-2.6005705568641115	[354]	[23,10]	-9	hSpCas9	negative selection	1120329
55546262	55546285	15	+	26627737	RPE1	viability after 12 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.29727947668548604	[871]	[385,183]	2	hSpCas9	negative selection	1202639
55546984	55547007	15	+	26627737	RPE1	viability after 12 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.2953017049658748	[1805]	[493,290]	-2	hSpCas9	negative selection	1202640
55548909	55548932	15	-	26627737	RPE1	viability after 12 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.18533106378080788	[1304]	[353,259]	-1	hSpCas9	negative selection	1202641
55548941	55548964	15	+	26627737	RPE1	viability after 12 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.2366648153099253	[826]	[156,221]	-2	hSpCas9	negative selection	1202642
55587836	55587859	15	+	26627737	RPE1	viability after 12 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.088756489615534	[1962]	[1179,1059]	6	hSpCas9	negative selection	1202643
55588812	55588835	15	+	26627737	RPE1	viability after 12 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.1541000342806298	[354]	[54,29]	-7	hSpCas9	negative selection	1202644
55546262	55546285	15	+	26627737	RPE1	viability after 15 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.23684626210821344	[871]	[364,218]	1	hSpCas9	negative selection	1284954
55546984	55547007	15	+	26627737	RPE1	viability after 15 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.529836427250587	[1805]	[305,399]	-3	hSpCas9	negative selection	1284955
55548909	55548932	15	-	26627737	RPE1	viability after 15 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.4342481422398614	[1304]	[565,433]	2	hSpCas9	negative selection	1284956
55548941	55548964	15	+	26627737	RPE1	viability after 15 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-1.106849889144855	[826]	[129,87]	-6	hSpCas9	negative selection	1284957
55587836	55587859	15	+	26627737	RPE1	viability after 15 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.1655264060699544	[1962]	[1436,1060]	6	hSpCas9	negative selection	1284958
55588812	55588835	15	+	26627737	RPE1	viability after 15 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.7726595596580892	[354]	[42,73]	-5	hSpCas9	negative selection	1284959
55546262	55546285	15	+	26627737	RPE1	viability after 18 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.1282258123493916	[871]	[238,189]	-1	hSpCas9	negative selection	1367269
55546984	55547007	15	+	26627737	RPE1	viability after 18 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.19817417210150534	[1805]	[448,398]	-1	hSpCas9	negative selection	1367270
55548909	55548932	15	-	26627737	RPE1	viability after 18 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.5274551642450596	[1304]	[554,456]	3	hSpCas9	negative selection	1367271
55548941	55548964	15	+	26627737	RPE1	viability after 18 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-2.0970407578080184	[826]	[56,46]	-8	hSpCas9	negative selection	1367272
55587836	55587859	15	+	26627737	RPE1	viability after 18 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.0415947222800521	[1962]	[1308,856]	6	hSpCas9	negative selection	1367273
55588812	55588835	15	+	26627737	RPE1	viability after 18 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.915088857653352	[354]	[7,43]	-8	hSpCas9	negative selection	1367274
55546262	55546285	15	+	26627737	HeLa	viability after 8 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.24402316004334906	[503]	[422,278,122]	2	hSpCas9	negative selection	1449584
55546984	55547007	15	+	26627737	HeLa	viability after 8 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.22672069687728935	[676]	[292,125,338]	-2	hSpCas9	negative selection	1449585
55548909	55548932	15	-	26627737	HeLa	viability after 8 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.15204666183387927	[643]	[276,246,238]	-1	hSpCas9	negative selection	1449586
55548941	55548964	15	+	26627737	HeLa	viability after 8 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.2465518134870039	[419]	[177,69,214]	-2	hSpCas9	negative selection	1449587
55587836	55587859	15	+	26627737	HeLa	viability after 8 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.2493545968001727	[919]	[490,435,501]	2	hSpCas9	negative selection	1449588
55588812	55588835	15	+	26627737	HeLa	viability after 8 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	4.380334203863134	[7]	[87,46,84]	9	hSpCas9	negative selection	1449589
55546262	55546285	15	+	26627737	HeLa	viability after 12 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.3702605607598173	[503]	[174,149,159]	-3	hSpCas9	negative selection	1531899
55546984	55547007	15	+	26627737	HeLa	viability after 12 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.23752313973353223	[676]	[79,268,354]	-2	hSpCas9	negative selection	1531900
55548909	55548932	15	-	26627737	HeLa	viability after 12 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.05801596199417358	[643]	[359,244,231]	0	hSpCas9	negative selection	1531901
55548941	55548964	15	+	26627737	HeLa	viability after 12 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.5984156970710701	[419]	[145,46,158]	-5	hSpCas9	negative selection	1531902
55587836	55587859	15	+	26627737	HeLa	viability after 12 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.5738042078681824	[919]	[882,489,341]	5	hSpCas9	negative selection	1531903
55588812	55588835	15	+	26627737	HeLa	viability after 12 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	4.2476906589147845	[7]	[34,77,72]	9	hSpCas9	negative selection	1531904
55546262	55546285	15	+	26627737	HeLa	viability after 15 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.4311323765675844	[503]	[155,129,171]	-4	hSpCas9	negative selection	1614214
55546984	55547007	15	+	26627737	HeLa	viability after 15 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.9869034946906572	[676]	[120,101,198]	-7	hSpCas9	negative selection	1614215
55548909	55548932	15	-	26627737	HeLa	viability after 15 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.13490316315911322	[643]	[142,281,296]	-1	hSpCas9	negative selection	1614216
55548941	55548964	15	+	26627737	HeLa	viability after 15 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.040568772721474494	[419]	[242,43,244]	0	hSpCas9	negative selection	1614217
55587836	55587859	15	+	26627737	HeLa	viability after 15 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.22281965142101523	[919]	[495,467,338]	2	hSpCas9	negative selection	1614218
55588812	55588835	15	+	26627737	HeLa	viability after 15 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	4.215409447596919	[7]	[17,79,85]	9	hSpCas9	negative selection	1614219
55546262	55546285	15	+	26627737	HeLa	viability after 18 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.44772835408232037	[503]	[104,102,171]	-4	hSpCas9	negative selection	1696529
55546984	55547007	15	+	26627737	HeLa	viability after 18 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.966535057496164	[676]	[82,86,198]	-7	hSpCas9	negative selection	1696530
55548909	55548932	15	-	26627737	HeLa	viability after 18 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.10950417628427844	[643]	[110,224,296]	-1	hSpCas9	negative selection	1696531
55548941	55548964	15	+	26627737	HeLa	viability after 18 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.0346874916849044	[419]	[161,35,244]	0	hSpCas9	negative selection	1696532
55587836	55587859	15	+	26627737	HeLa	viability after 18 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.22584924851406685	[919]	[342,376,338]	2	hSpCas9	negative selection	1696533
55588812	55588835	15	+	26627737	HeLa	viability after 18 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	4.194776906257893	[7]	[12,62,85]	9	hSpCas9	negative selection	1696534
55546262	55546285	15	+	26627737	HCT116	viability after 6 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.8633993812171545	[493]	[139,141]	5	hSpCas9	negative selection	1778844
55546984	55547007	15	+	26627737	HCT116	viability after 6 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.24393182180426232	[1261]	[38,342]	1	hSpCas9	negative selection	1778845
55548909	55548932	15	-	26627737	HCT116	viability after 6 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.10189403642010847	[783]	[246,68]	0	hSpCas9	negative selection	1778846
55548941	55548964	15	+	26627737	HCT116	viability after 6 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-3.675667791848269	[521]	[8,4]	-9	hSpCas9	negative selection	1778847
55587836	55587859	15	+	26627737	HCT116	viability after 6 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	-0.8992938715509398	[1363]	[181,77]	-5	hSpCas9	negative selection	1778848
55588812	55588835	15	+	26627737	HCT116	viability after 6 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.9227565232272905	[110]	[83,4]	5	hSpCas9	negative selection	1778849
55546262	55546285	15	+	26627737	HCT116	viability after 8 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.11295742009592583	[340]	[192,177,237]	1	hSpCas9	negative selection	1861159
55546984	55547007	15	+	26627737	HCT116	viability after 8 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.08196800204953636	[534]	[224,269,437]	1	hSpCas9	negative selection	1861160
55548909	55548932	15	-	26627737	HCT116	viability after 8 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.41752989044115457	[380]	[266,212,359]	4	hSpCas9	negative selection	1861161
55548941	55548964	15	+	26627737	HCT116	viability after 8 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.24130551531078626	[201]	[103,111,66]	-3	hSpCas9	negative selection	1861162
55587836	55587859	15	+	26627737	HCT116	viability after 8 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.12655486146752515	[712]	[500,440,346]	1	hSpCas9	negative selection	1861163
55588812	55588835	15	+	26627737	HCT116	viability after 8 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.3508219048438233	[26]	[48,23,40]	9	hSpCas9	negative selection	1861164
55546262	55546285	15	+	26627737	HCT116	viability after 9 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	1.397510448341362	[493]	[232,437]	8	hSpCas9	negative selection	1943474
55546984	55547007	15	+	26627737	HCT116	viability after 9 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.2163787128673873	[1261]	[648,187]	1	hSpCas9	negative selection	1943475
55548909	55548932	15	-	26627737	HCT116	viability after 9 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.6414016936329746	[783]	[260,33]	-4	hSpCas9	negative selection	1943476
55548941	55548964	15	+	26627737	HCT116	viability after 9 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.6947301168851155	[521]	[257,199]	5	hSpCas9	negative selection	1943477
55587836	55587859	15	+	26627737	HCT116	viability after 9 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	-0.5350764824168974	[1363]	[371,155]	-4	hSpCas9	negative selection	1943478
55588812	55588835	15	+	26627737	HCT116	viability after 9 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.6009821788778797	[110]	[73,21]	4	hSpCas9	negative selection	1943479
55546262	55546285	15	+	26627737	HCT116	viability after 12 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.059964373510769414	[340]	[122,170,225]	0	hSpCas9	negative selection	2025789
55546984	55547007	15	+	26627737	HCT116	viability after 12 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.351304537914449	[534]	[300,133,216]	-4	hSpCas9	negative selection	2025790
55548909	55548932	15	-	26627737	HCT116	viability after 12 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.43014404810792656	[380]	[266,245,295]	4	hSpCas9	negative selection	2025791
55548941	55548964	15	+	26627737	HCT116	viability after 12 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.1742872245375504	[201]	[84,92,104]	-2	hSpCas9	negative selection	2025792
55587836	55587859	15	+	26627737	HCT116	viability after 12 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	-0.04632151657318717	[712]	[282,461,352]	0	hSpCas9	negative selection	2025793
55588812	55588835	15	+	26627737	HCT116	viability after 12 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.4473767513828233	[26]	[16,38,61]	9	hSpCas9	negative selection	2025794
55546262	55546285	15	+	26627737	HCT116	viability after 15 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.01853856930062464	[340]	[154,198,220]	0	hSpCas9	negative selection	2108104
55546984	55547007	15	+	26627737	HCT116	viability after 15 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.4040113997083012	[534]	[291,188,222]	-4	hSpCas9	negative selection	2108105
55548909	55548932	15	-	26627737	HCT116	viability after 15 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.1547516357871954	[380]	[316,147,139]	-2	hSpCas9	negative selection	2108106
55548941	55548964	15	+	26627737	HCT116	viability after 15 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.23540224158851264	[201]	[76,116,98]	-2	hSpCas9	negative selection	2108107
55587836	55587859	15	+	26627737	HCT116	viability after 15 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.20389487821568952	[712]	[644,402,388]	2	hSpCas9	negative selection	2108108
55588812	55588835	15	+	26627737	HCT116	viability after 15 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.4927790194056276	[26]	[58,47,25]	9	hSpCas9	negative selection	2108109
55546262	55546285	15	+	26627737	HCT116	viability after 18 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.3135021838785498	[340]	[108,180,331]	2	hSpCas9	negative selection	2190419
55546984	55547007	15	+	26627737	HCT116	viability after 18 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.7602629763170805	[534]	[101,182,171]	-6	hSpCas9	negative selection	2190420
55548909	55548932	15	-	26627737	HCT116	viability after 18 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.46693976369687334	[380]	[348,230,181]	4	hSpCas9	negative selection	2190421
55548941	55548964	15	+	26627737	HCT116	viability after 18 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.04493122625520363	[201]	[92,60,133]	0	hSpCas9	negative selection	2190422
55587836	55587859	15	+	26627737	HCT116	viability after 18 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.1861316166443967	[712]	[405,407,359]	1	hSpCas9	negative selection	2190423
55588812	55588835	15	+	26627737	HCT116	viability after 18 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.8224424818662799	[26]	[31,12,24]	6	hSpCas9	negative selection	2190424
55548947	55548970	15	-	24336569	HL60	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.20731571804145332	[360]	[881]	2	hSpCas9	negative selection	2287787
55548959	55548982	15	-	24336569	HL60	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.08305035152084772	[454]	[908]	0	hSpCas9	negative selection	2287788
55548965	55548988	15	-	24336569	HL60	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	1.1904955349843813	[234]	[1134]	8	hSpCas9	negative selection	2287789
55548973	55548996	15	-	24336569	HL60	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	1.6898019511608289	[132]	[907]	9	hSpCas9	negative selection	2287790
55548978	55549001	15	-	24336569	HL60	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	0.6799584480590443	[309]	[1050]	6	hSpCas9	negative selection	2287791
55588790	55588813	15	+	24336569	HL60	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.4158116595567829	[1073]	[3031]	4	hSpCas9	negative selection	2287792
55588803	55588826	15	-	24336569	HL60	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.12055453052326953	[488]	[1124]	1	hSpCas9	negative selection	2287793
55588812	55588835	15	+	24336569	HL60	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.6637220003422784	[209]	[703]	5	hSpCas9	negative selection	2287794
55588823	55588846	15	+	24336569	HL60	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	-1.8152111880706499	[596]	[358]	-9	hSpCas9	negative selection	2287795
55588834	55588857	15	+	24336569	HL60	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	-0.6962074400958091	[672]	[878]	-6	hSpCas9	negative selection	2287796
55548947	55548970	15	-	24336569	KBM7	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	-0.3651170363569094	[339]	[719]	-3	hSpCas9	negative selection	2354964
55548959	55548982	15	-	24336569	KBM7	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.8531635684478517	[342]	[1689]	7	hSpCas9	negative selection	2354965
55548965	55548988	15	-	24336569	KBM7	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	0.19319007005935068	[523]	[1633]	1	hSpCas9	negative selection	2354966
55548973	55548996	15	-	24336569	KBM7	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.7271628211912058	[298]	[1349]	6	hSpCas9	negative selection	2354967
55548978	55549001	15	-	24336569	KBM7	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	0.620900541333884	[359]	[1509]	5	hSpCas9	negative selection	2354968
55588790	55588813	15	+	24336569	KBM7	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.24167838836011657	[1075]	[3469]	2	hSpCas9	negative selection	2354969
55588803	55588826	15	-	24336569	KBM7	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	-0.606554250601642	[483]	[866]	-5	hSpCas9	negative selection	2354970
55588812	55588835	15	+	24336569	KBM7	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.22829180037048413	[40]	[130]	2	hSpCas9	negative selection	2354971
55588823	55588846	15	+	24336569	KBM7	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	0.3996317143228347	[305]	[1100]	3	hSpCas9	negative selection	2354972
55588834	55588857	15	+	24336569	KBM7	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	0.7127149611116066	[333]	[1492]	6	hSpCas9	negative selection	2354973
55548973	55548995	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.021694669815692652	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2381225
55548973	55548995	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.021694669815692652	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2381226
55548973	55548995	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.021694669815692652	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2381227
55548947	55548969	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	4.589782102605957	[1268,1050,1037]	[0,29,0]	7	hSpCas9	positive selection	2381228
55548947	55548969	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	4.589782102605957	[1268,1050,1037]	[0,29,0]	7	hSpCas9	positive selection	2381229
55548947	55548969	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	4.589782102605957	[1268,1050,1037]	[0,29,0]	7	hSpCas9	positive selection	2381230
55548921	55548944	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	2.941440454899507	[5041,4408,4670]	[40,0,0]	6	hSpCas9	positive selection	2381231
55548921	55548944	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	2.941440454899507	[5041,4408,4670]	[40,0,0]	6	hSpCas9	positive selection	2381232
55548921	55548944	15	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	2.941440454899507	[5041,4408,4670]	[40,0,0]	6	hSpCas9	positive selection	2381233
55548973	55548995	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.02081147274665875	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2382550
55548973	55548995	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.02081147274665875	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2382551
55548973	55548995	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.02081147274665875	[2981,2588,1908]	[0,0,0]	0	hSpCas9	positive selection	2382552
55548947	55548969	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	5.204251670099534	[1268,1050,1037]	[46,0,0]	8	hSpCas9	positive selection	2382553
55548947	55548969	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	5.204251670099534	[1268,1050,1037]	[46,0,0]	8	hSpCas9	positive selection	2382554
55548947	55548969	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	5.204251670099534	[1268,1050,1037]	[46,0,0]	8	hSpCas9	positive selection	2382555
55548921	55548944	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	4.753513205223175	[5041,4408,4670]	[148,0,0]	7	hSpCas9	positive selection	2382556
55548921	55548944	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	4.753513205223175	[5041,4408,4670]	[148,0,0]	7	hSpCas9	positive selection	2382557
55548921	55548944	15	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	4.753513205223175	[5041,4408,4670]	[148,0,0]	7	hSpCas9	positive selection	2382558
55572961	55572984	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTCAAGATCAGCCAAG	PYGO1	ENSG00000171016	1.0000949637067877	[26,25]	[19,2]	4	dCas9-VP64	positive selection	2426233
55572961	55572984	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTCAAGATCAGCCAAG	PYGO1	ENSG00000171016	-1.1816738048605875	[96,64]	[6,14]	-9	dCas9-VP64	positive selection	2521488
55548973	55548996	15	-	27260157	DLD1	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	1.00652633864755	[]	[]	9	hSpCas9	negative selection	2575442
55547110	55547133	15	+	27260157	DLD1	viability	GGTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	-0.399765400654557	[]	[]	-3	hSpCas9	negative selection	2581233
55548978	55549001	15	-	27260157	DLD1	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	-0.390624320683212	[]	[]	-3	hSpCas9	negative selection	2582377
55547081	55547104	15	-	27260157	DLD1	viability	TCCAAACTCTGACCATCTAGTGG	PYGO1	ENSG00000171016	0.1440502592562	[]	[]	3	hSpCas9	negative selection	2583984
55547122	55547145	15	+	27260157	DLD1	viability	TCAGACAATGGAGGGAAAGAAGG	PYGO1	ENSG00000171016	0.0427596628578816	[]	[]	0	hSpCas9	negative selection	2584619
55548947	55548970	15	-	27260157	DLD1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.324395611406143	[]	[]	4	hSpCas9	negative selection	2587558
55547080	55547103	15	+	27260157	DLD1	viability	GCCACTAGATGGTCAGAGTTTGG	PYGO1	ENSG00000171016	0.281452808240179	[]	[]	4	hSpCas9	negative selection	2608324
55547069	55547092	15	+	27260157	DLD1	viability	ATGGATTAGCAGCCACTAGATGG	PYGO1	ENSG00000171016	0.58430556420251	[]	[]	8	hSpCas9	negative selection	2610113
55588790	55588813	15	+	27260157	DLD1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.17319609061292	[]	[]	3	hSpCas9	negative selection	2612501
55547092	55547115	15	+	27260157	DLD1	viability	TCAGAGTTTGGATTCGGTGGTGG	PYGO1	ENSG00000171016	0.6032887002203	[]	[]	8	hSpCas9	negative selection	2613072
55547002	55547025	15	-	27260157	DLD1	viability	TCAAATCCATATCTTGGCCCTGG	PYGO1	ENSG00000171016	0.146334213698928	[]	[]	3	hSpCas9	negative selection	2617344
55588812	55588835	15	+	27260157	DLD1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.05850853540473	[]	[]	-7	hSpCas9	negative selection	2620793
55548941	55548964	15	+	27260157	DLD1	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.266840496517891	[]	[]	4	hSpCas9	negative selection	2640928
55548959	55548982	15	-	27260157	DLD1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.469561833191802	[]	[]	8	hSpCas9	negative selection	2641339
55546996	55547019	15	+	27260157	DLD1	viability	GGATAACCAGGGCCAAGATATGG	PYGO1	ENSG00000171016	-0.585793834018639	[]	[]	-5	hSpCas9	negative selection	2642162
55588823	55588846	15	+	27260157	DLD1	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	0.453015374581204	[]	[]	7	hSpCas9	negative selection	2644890
55588834	55588857	15	+	27260157	DLD1	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	-0.740593864715333	[]	[]	-5	hSpCas9	negative selection	2647692
55548965	55548988	15	-	27260157	DLD1	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	0.664493787574886	[]	[]	8	hSpCas9	negative selection	2649536
55548973	55548996	15	-	27260157	HT1080	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.646278845018088	[]	[]	5	hSpCas9	negative selection	2651572
55547110	55547133	15	+	27260157	HT1080	viability	GGTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.146463871417346	[]	[]	1	hSpCas9	negative selection	2657363
55548978	55549001	15	-	27260157	HT1080	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	-0.321782551314884	[]	[]	-7	hSpCas9	negative selection	2658507
55547081	55547104	15	-	27260157	HT1080	viability	TCCAAACTCTGACCATCTAGTGG	PYGO1	ENSG00000171016	-0.767150657376675	[]	[]	-8	hSpCas9	negative selection	2660114
55547122	55547145	15	+	27260157	HT1080	viability	TCAGACAATGGAGGGAAAGAAGG	PYGO1	ENSG00000171016	1.08768786880368	[]	[]	8	hSpCas9	negative selection	2660749
55548947	55548970	15	-	27260157	HT1080	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	-0.311302764376327	[]	[]	-7	hSpCas9	negative selection	2663688
55547080	55547103	15	+	27260157	HT1080	viability	GCCACTAGATGGTCAGAGTTTGG	PYGO1	ENSG00000171016	0.512512224454568	[]	[]	4	hSpCas9	negative selection	2684454
55547069	55547092	15	+	27260157	HT1080	viability	ATGGATTAGCAGCCACTAGATGG	PYGO1	ENSG00000171016	1.01520715604034	[]	[]	8	hSpCas9	negative selection	2686243
55588790	55588813	15	+	27260157	HT1080	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	-0.32938382201862	[]	[]	-7	hSpCas9	negative selection	2688631
55547092	55547115	15	+	27260157	HT1080	viability	TCAGAGTTTGGATTCGGTGGTGG	PYGO1	ENSG00000171016	-0.652177732083865	[]	[]	-8	hSpCas9	negative selection	2689202
55547002	55547025	15	-	27260157	HT1080	viability	TCAAATCCATATCTTGGCCCTGG	PYGO1	ENSG00000171016	0.189594035868972	[]	[]	1	hSpCas9	negative selection	2693474
55588812	55588835	15	+	27260157	HT1080	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.254528405697473	[]	[]	2	hSpCas9	negative selection	2696923
55548941	55548964	15	+	27260157	HT1080	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.330686060556111	[]	[]	-7	hSpCas9	negative selection	2717058
55548959	55548982	15	-	27260157	HT1080	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.439846236581455	[]	[]	4	hSpCas9	negative selection	2717469
55546996	55547019	15	+	27260157	HT1080	viability	GGATAACCAGGGCCAAGATATGG	PYGO1	ENSG00000171016	0.0898333418384755	[]	[]	1	hSpCas9	negative selection	2718292
55588823	55588846	15	+	27260157	HT1080	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	0.834918184104199	[]	[]	7	hSpCas9	negative selection	2721020
55588834	55588857	15	+	27260157	HT1080	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	-0.335640107307274	[]	[]	-7	hSpCas9	negative selection	2723822
55548965	55548988	15	-	27260157	HT1080	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	-0.620808034429733	[]	[]	-8	hSpCas9	negative selection	2725666
55548973	55548996	15	-	27260157	MKN45	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.405157592788538	[]	[]	6	hSpCas9	negative selection	2727702
55547110	55547133	15	+	27260157	MKN45	viability	GGTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.109349857139292	[]	[]	4	hSpCas9	negative selection	2733493
55548978	55549001	15	-	27260157	MKN45	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	-0.249816189217261	[]	[]	-1	hSpCas9	negative selection	2734637
55547081	55547104	15	-	27260157	MKN45	viability	TCCAAACTCTGACCATCTAGTGG	PYGO1	ENSG00000171016	-0.951653643287271	[]	[]	-7	hSpCas9	negative selection	2736244
55547122	55547145	15	+	27260157	MKN45	viability	TCAGACAATGGAGGGAAAGAAGG	PYGO1	ENSG00000171016	0.677857702844867	[]	[]	7	hSpCas9	negative selection	2736879
55548947	55548970	15	-	27260157	MKN45	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.853275510689232	[]	[]	8	hSpCas9	negative selection	2739818
55547080	55547103	15	+	27260157	MKN45	viability	GCCACTAGATGGTCAGAGTTTGG	PYGO1	ENSG00000171016	0.612822495210058	[]	[]	7	hSpCas9	negative selection	2760584
55547069	55547092	15	+	27260157	MKN45	viability	ATGGATTAGCAGCCACTAGATGG	PYGO1	ENSG00000171016	0.544166981724657	[]	[]	7	hSpCas9	negative selection	2762373
55588790	55588813	15	+	27260157	MKN45	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.346591802288782	[]	[]	6	hSpCas9	negative selection	2764761
55547092	55547115	15	+	27260157	MKN45	viability	TCAGAGTTTGGATTCGGTGGTGG	PYGO1	ENSG00000171016	-0.235141932963558	[]	[]	-1	hSpCas9	negative selection	2765332
55547002	55547025	15	-	27260157	MKN45	viability	TCAAATCCATATCTTGGCCCTGG	PYGO1	ENSG00000171016	0.569602681273616	[]	[]	7	hSpCas9	negative selection	2769604
55588812	55588835	15	+	27260157	MKN45	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.351680875178159	[]	[]	-1	hSpCas9	negative selection	2773053
55548941	55548964	15	+	27260157	MKN45	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.611474524831176	[]	[]	7	hSpCas9	negative selection	2793188
55548959	55548982	15	-	27260157	MKN45	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.179312240283625	[]	[]	5	hSpCas9	negative selection	2793599
55546996	55547019	15	+	27260157	MKN45	viability	GGATAACCAGGGCCAAGATATGG	PYGO1	ENSG00000171016	-0.056293329315043	[]	[]	0	hSpCas9	negative selection	2794422
55588823	55588846	15	+	27260157	MKN45	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	1.14413578078692	[]	[]	8	hSpCas9	negative selection	2797150
55588834	55588857	15	+	27260157	MKN45	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	-0.159239131454753	[]	[]	0	hSpCas9	negative selection	2799952
55548965	55548988	15	-	27260157	MKN45	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	0.718187605365135	[]	[]	7	hSpCas9	negative selection	2801796
55548973	55548996	15	-	27260157	RKO	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.602838439391762	[]	[]	3	hSpCas9	negative selection	2803832
55547110	55547133	15	+	27260157	RKO	viability	GGTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	-0.0537400687876992	[]	[]	0	hSpCas9	negative selection	2809623
55548978	55549001	15	-	27260157	RKO	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	-0.172968783376151	[]	[]	-1	hSpCas9	negative selection	2810767
55547081	55547104	15	-	27260157	RKO	viability	TCCAAACTCTGACCATCTAGTGG	PYGO1	ENSG00000171016	-0.920411184885154	[]	[]	-8	hSpCas9	negative selection	2812374
55547122	55547145	15	+	27260157	RKO	viability	TCAGACAATGGAGGGAAAGAAGG	PYGO1	ENSG00000171016	0.298557604016694	[]	[]	1	hSpCas9	negative selection	2813009
55548947	55548970	15	-	27260157	RKO	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.19548464229893	[]	[]	1	hSpCas9	negative selection	2815948
55547080	55547103	15	+	27260157	RKO	viability	GCCACTAGATGGTCAGAGTTTGG	PYGO1	ENSG00000171016	0.405823028991801	[]	[]	2	hSpCas9	negative selection	2836714
55547069	55547092	15	+	27260157	RKO	viability	ATGGATTAGCAGCCACTAGATGG	PYGO1	ENSG00000171016	1.16979988893019	[]	[]	9	hSpCas9	negative selection	2838503
55588790	55588813	15	+	27260157	RKO	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.0368144153552373	[]	[]	0	hSpCas9	negative selection	2840891
55547092	55547115	15	+	27260157	RKO	viability	TCAGAGTTTGGATTCGGTGGTGG	PYGO1	ENSG00000171016	-0.305762716584265	[]	[]	-6	hSpCas9	negative selection	2841462
55547002	55547025	15	-	27260157	RKO	viability	TCAAATCCATATCTTGGCCCTGG	PYGO1	ENSG00000171016	-0.161696728683676	[]	[]	-1	hSpCas9	negative selection	2845734
55588812	55588835	15	+	27260157	RKO	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.810082672955375	[]	[]	8	hSpCas9	negative selection	2849183
55548941	55548964	15	+	27260157	RKO	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.66258304562506	[]	[]	3	hSpCas9	negative selection	2869318
55548959	55548982	15	-	27260157	RKO	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.145811429597754	[]	[]	0	hSpCas9	negative selection	2869729
55546996	55547019	15	+	27260157	RKO	viability	GGATAACCAGGGCCAAGATATGG	PYGO1	ENSG00000171016	-0.39299593944649	[]	[]	-6	hSpCas9	negative selection	2870552
55588823	55588846	15	+	27260157	RKO	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	0.213037469210226	[]	[]	1	hSpCas9	negative selection	2873280
55588834	55588857	15	+	27260157	RKO	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	-0.174783108127697	[]	[]	-1	hSpCas9	negative selection	2876082
55548965	55548988	15	-	27260157	RKO	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	-0.221541752318514	[]	[]	-1	hSpCas9	negative selection	2877926
55548973	55548996	15	-	27260157	SF268	viability	GTGGTGATAGTGGACTGGATGGG	PYGO1	ENSG00000171016	0.584612163716321	[]	[]	8	hSpCas9	negative selection	2879962
55547110	55547133	15	+	27260157	SF268	viability	GGTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	-0.433545459780203	[]	[]	-3	hSpCas9	negative selection	2885753
55548978	55549001	15	-	27260157	SF268	viability	TTTAGGTGGTGATAGTGGACTGG	PYGO1	ENSG00000171016	0.209425592654309	[]	[]	3	hSpCas9	negative selection	2886897
55547081	55547104	15	-	27260157	SF268	viability	TCCAAACTCTGACCATCTAGTGG	PYGO1	ENSG00000171016	0.0179811341306674	[]	[]	0	hSpCas9	negative selection	2888504
55547122	55547145	15	+	27260157	SF268	viability	TCAGACAATGGAGGGAAAGAAGG	PYGO1	ENSG00000171016	0.341067822103292	[]	[]	4	hSpCas9	negative selection	2889139
55548947	55548970	15	-	27260157	SF268	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.974663333186506	[]	[]	9	hSpCas9	negative selection	2892078
55547080	55547103	15	+	27260157	SF268	viability	GCCACTAGATGGTCAGAGTTTGG	PYGO1	ENSG00000171016	1.0548297765508	[]	[]	9	hSpCas9	negative selection	2912844
55547069	55547092	15	+	27260157	SF268	viability	ATGGATTAGCAGCCACTAGATGG	PYGO1	ENSG00000171016	1.27222748012157	[]	[]	9	hSpCas9	negative selection	2914633
55588790	55588813	15	+	27260157	SF268	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.312616745043488	[]	[]	4	hSpCas9	negative selection	2917021
55547092	55547115	15	+	27260157	SF268	viability	TCAGAGTTTGGATTCGGTGGTGG	PYGO1	ENSG00000171016	0.345966477041662	[]	[]	4	hSpCas9	negative selection	2917592
55547002	55547025	15	-	27260157	SF268	viability	TCAAATCCATATCTTGGCCCTGG	PYGO1	ENSG00000171016	0.245299240157109	[]	[]	3	hSpCas9	negative selection	2921864
55588812	55588835	15	+	27260157	SF268	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.476223410184899	[]	[]	-4	hSpCas9	negative selection	2925313
55548941	55548964	15	+	27260157	SF268	viability	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.144136969553923	[]	[]	-1	hSpCas9	negative selection	2945448
55548959	55548982	15	-	27260157	SF268	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.111254646501002	[]	[]	-1	hSpCas9	negative selection	2945859
55546996	55547019	15	+	27260157	SF268	viability	GGATAACCAGGGCCAAGATATGG	PYGO1	ENSG00000171016	1.52577293279368	[]	[]	9	hSpCas9	negative selection	2946682
55588823	55588846	15	+	27260157	SF268	viability	AGCGGGAGCTGGAGAGTTCTCGG	PYGO1	ENSG00000171016	1.29869903314117	[]	[]	9	hSpCas9	negative selection	2949410
55588834	55588857	15	+	27260157	SF268	viability	GAGAGTTCTCGGCGGGCATGTGG	PYGO1	ENSG00000171016	0.426761797399003	[]	[]	4	hSpCas9	negative selection	2952212
55548965	55548988	15	-	27260157	SF268	viability	AGTGGACTGGATGGGTTAGGAGG	PYGO1	ENSG00000171016	0.205809707344927	[]	[]	3	hSpCas9	negative selection	2954056
55546859	55546882	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.21170157129435652	[4,4]	[4,1]	-3	hSpCas9	positive selection	3014989
55546986	55547009	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	-0.8626250438772519	[3,3]	[0,1]	-8	hSpCas9	positive selection	3014990
55547115	55547138	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	-0.05359001436521341	[3,3]	[2,2]	0	hSpCas9	positive selection	3014991
55546931	55546954	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	0.2153940228297228	[3,4]	[3,3]	4	hSpCas9	positive selection	3014992
55546859	55546882	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.25633767402582486	[4,4]	[3,1]	-4	hSpCas9	positive selection	3082847
55546986	55547009	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	-0.6468004030784112	[3,3]	[3,0]	-8	hSpCas9	positive selection	3082848
55547115	55547138	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	-0.04695561470470036	[3,3]	[3,0]	0	hSpCas9	positive selection	3082849
55546931	55546954	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	0.3459148708716252	[3,3]	[3,2]	6	hSpCas9	positive selection	3082850
55588805	55588828		+	24336571	A375	resistance to PLX after 7 days	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.24310962379825507	[5,5]	[4,4]	-7	hSpCas9	positive selection	3139112
55548920	55548943		+	24336571	A375	resistance to PLX after 7 days	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	-0.06568126458845563	[15,17]	[16,14]	-2	hSpCas9	positive selection	3139113
55588805	55588828		+	24336571	A375	resistance to PLX after 14 days	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.3541836913524634	[4,3]	[1,2]	3	hSpCas9	positive selection	3196905
55548920	55548943		+	24336571	A375	resistance to PLX after 14 days	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	0.23446799411557928	[21,18]	[9,12]	2	hSpCas9	positive selection	3196906
55588805	55588828		+	24336571	A375	viability after 7 days	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.08461448500074842	[5]	[5,5]	1	hSpCas9	negative selection	3254698
55548920	55548943		+	24336571	A375	viability after 7 days	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	0.2546790601119527	[14]	[15,17]	4	hSpCas9	negative selection	3254699
55588805	55588828		+	24336571	A375	viability after 14 days	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.35816743132539663	[5]	[4,3]	-4	hSpCas9	negative selection	3312491
55548920	55548943		+	24336571	A375	viability after 14 days	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	0.521702452803354	[14]	[21,18]	6	hSpCas9	negative selection	3312492
55548921	55548944	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3388477
55588805	55588828	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.25732621144583506	[127,127]	[0,0]	1	hSpCas9	positive selection	3388478
55548959	55548982	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3388479
55546858	55546881	15	+	26780180	HT29	viability (Avana library 4 designs)	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	1.10354841165662	[]	[]	4	hSpCas9	negative selection	3453239
55546985	55547008	15	+	26780180	HT29	viability (Avana library 4 designs)	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	-0.48045137521094	[]	[]	-7	hSpCas9	negative selection	3453240
55547114	55547137	15	+	26780180	HT29	viability (Avana library 4 designs)	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	-0.189749006481961	[]	[]	-3	hSpCas9	negative selection	3453241
55546930	55546953	15	+	26780180	HT29	viability (Avana library 4 designs)	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	0.58916673470382	[]	[]	2	hSpCas9	negative selection	3453242
55546985	55547008	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	-6.02422525699812	[]	[]	-6	hSpCas9	negative selection	3550002
55546858	55546881	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	1.86843378420493	[]	[]	2	hSpCas9	negative selection	3550003
55546930	55546953	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	-4.58866694577645	[]	[]	-5	hSpCas9	negative selection	3550004
55547114	55547137	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	-2.64050463478077	[]	[]	-3	hSpCas9	negative selection	3550005
55588827	55588850	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCTGGAGAGTTCTCGGCGGG	PYGO1	ENSG00000171016	-6.45094162650722	[]	[]	-6	hSpCas9	negative selection	3550006
55547014	55547037	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATGGATTTGACGAAGGTAGTGG	PYGO1	ENSG00000171016	1.64619219521238	[]	[]	2	hSpCas9	negative selection	3550007
55546985	55547008	15	+	26780180	A375	viability (Avana lentiGuide)	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	1.48104997105646	[]	[]	1	hSpCas9	negative selection	3658661
55546858	55546881	15	+	26780180	A375	viability (Avana lentiGuide)	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-4.31270350453834	[]	[]	-7	hSpCas9	negative selection	3658662
55546930	55546953	15	+	26780180	A375	viability (Avana lentiGuide)	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	0.192823366242054	[]	[]	0	hSpCas9	negative selection	3658663
55547114	55547137	15	+	26780180	A375	viability (Avana lentiGuide)	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	0.0805042457481994	[]	[]	0	hSpCas9	negative selection	3658664
55588827	55588850	15	+	26780180	A375	viability (Avana lentiGuide)	GGAGCTGGAGAGTTCTCGGCGGG	PYGO1	ENSG00000171016	5.47051534864466	[]	[]	5	hSpCas9	negative selection	3658665
55547014	55547037	15	+	26780180	A375	viability (Avana lentiGuide)	TATGGATTTGACGAAGGTAGTGG	PYGO1	ENSG00000171016	-1.21841118366377	[]	[]	-2	hSpCas9	negative selection	3658666
55546985	55547008	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	-0.25868656226668396	[4]	[4,2]	-4	hSpCas9	positive selection	3767268
55546858	55546881	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.08453908781185254	[5]	[5,5]	2	hSpCas9	positive selection	3767269
55546930	55546953	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	-0.13067647877112773	[5]	[5,4]	-2	hSpCas9	positive selection	3767270
55547114	55547137	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	-0.33324647101858074	[5]	[3,4]	-5	hSpCas9	positive selection	3767271
55588827	55588850	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCTGGAGAGTTCTCGGCGGG	PYGO1	ENSG00000171016	-0.1395460871498022	[3]	[2,2]	-2	hSpCas9	positive selection	3767272
55547014	55547037	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGGATTTGACGAAGGTAGTGG	PYGO1	ENSG00000171016	0.1338562749613691	[6]	[6,6]	3	hSpCas9	positive selection	3767273
55546985	55547008	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCCAAAGCCAGGATAACCAGGG	PYGO1	ENSG00000171016	0.0874137554256892	[4]	[3,4]	2	hSpCas9	positive selection	3875875
55546858	55546881	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.20703637460568203	[5]	[4,3]	-3	hSpCas9	positive selection	3875876
55546930	55546953	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGGGGAAGACATTCTTGGGGG	PYGO1	ENSG00000171016	0.29282869473493767	[5]	[6,5]	7	hSpCas9	positive selection	3875877
55547114	55547137	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCATACTCAGACAATGGAGGG	PYGO1	ENSG00000171016	0.42311904599373673	[4]	[5,5]	9	hSpCas9	positive selection	3875878
55588827	55588850	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCTGGAGAGTTCTCGGCGGG	PYGO1	ENSG00000171016	-0.06628314761328263	[5]	[4,3]	-1	hSpCas9	positive selection	3875879
55547014	55547037	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGGATTTGACGAAGGTAGTGG	PYGO1	ENSG00000171016	0.20964217462256352	[6]	[6,6]	5	hSpCas9	positive selection	3875880
55588805	55588828	15	+	26780180	A375	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	1.18941803263123	[]	[]	6	hSpCas9	negative selection	3986298
55546682	55546705	15	-	26780180	A375	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.285762845005588	[]	[]	0	hSpCas9	negative selection	3986299
55548921	55548944	15	-	26780180	A375	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.85951877085626	[]	[]	3	hSpCas9	negative selection	3986300
55548959	55548982	15	-	26780180	A375	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	1.66606807312223	[]	[]	8	hSpCas9	negative selection	3986301
55588803	55588826	15	-	26780180	A375	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	1.32801724573444	[]	[]	7	hSpCas9	negative selection	3986302
55546058	55546081	15	+	26780180	A375	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.910173275765228	[]	[]	4	hSpCas9	negative selection	3986303
55588805	55588828	15	+	26780180	HT29	viability (GeCKOv2 library)	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	1.39812665893145	[]	[]	7	hSpCas9	negative selection	4094264
55546682	55546705	15	-	26780180	HT29	viability (GeCKOv2 library)	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	-0.189806386519996	[]	[]	-5	hSpCas9	negative selection	4094265
55548921	55548944	15	-	26780180	HT29	viability (GeCKOv2 library)	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.81668489929959	[]	[]	3	hSpCas9	negative selection	4094266
55548959	55548982	15	-	26780180	HT29	viability (GeCKOv2 library)	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	1.84621853381945	[]	[]	8	hSpCas9	negative selection	4094267
55588803	55588826	15	-	26780180	HT29	viability (GeCKOv2 library)	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.446419430695924	[]	[]	1	hSpCas9	negative selection	4094268
55546058	55546081	15	+	26780180	HT29	viability (GeCKOv2 library)	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.911285738491786	[]	[]	4	hSpCas9	negative selection	4094269
55588805	55588828	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.416329083210919	[2]	[1,0]	-8	hSpCas9	positive selection	4164418
55548920	55548943	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	0.16525687925193377	[3]	[2,3]	4	hSpCas9	positive selection	4164419
55588805	55588828	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.7001227796646861	[0]	[0,0,0,0]	4	hSpCas9	positive selection	4228440
55548920	55548943	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCTTGCGCTTTTTCTTATCTGG	PYGO1	ENSG00000171016	0.5454535155469303	[3]	[4,4,2,0]	4	hSpCas9	positive selection	4228441
55546682	55546705	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.061267925592206285	[3]	[3,2]	1	hSpCas9	positive selection	4293325
55546058	55546081	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.14954045528331972	[4]	[3,3]	3	hSpCas9	positive selection	4293326
55588803	55588826	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.0012877189639058373	[3]	[3,1]	0	hSpCas9	positive selection	4293327
55548921	55548944	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.03114253583917044	[3]	[3,1]	0	hSpCas9	positive selection	4357583
55588805	55588828	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.003647105689519453	[2]	[2,1]	0	hSpCas9	positive selection	4357584
55548959	55548982	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.17472429332491096	[3]	[1,1]	-4	hSpCas9	positive selection	4357585
55546671	55546693	15	+	27760321	OCIAML3	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.506892123982406	[226,219]	[147,90]	-5	hSpCas9	negative selection	4432269
55546835	55546857	15	+	27760321	OCIAML3	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.04212365476693236	[236,158]	[126,196]	0	hSpCas9	negative selection	4432270
55546859	55546881	15	+	27760321	OCIAML3	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.6520845346456241	[361,347]	[367,526]	7	hSpCas9	negative selection	4432271
55547009	55547031	15	+	27760321	OCIAML3	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	0.6042721470210252	[312,227]	[176,502]	7	hSpCas9	negative selection	4432272
55547111	55547133	15	+	27760321	OCIAML3	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	-0.12217674810638546	[310,246]	[167,239]	-1	hSpCas9	negative selection	4432273
55546671	55546693	15	+	27760321	OCIAML2	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	0.11431641057616293	[226,219]	[180,215]	1	hSpCas9	negative selection	4515732
55546835	55546857	15	+	27760321	OCIAML2	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.2522777620480988	[236,158]	[161,222]	3	hSpCas9	negative selection	4515733
55546859	55546881	15	+	27760321	OCIAML2	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.582155641694246	[361,347]	[418,445]	7	hSpCas9	negative selection	4515734
55547009	55547031	15	+	27760321	OCIAML2	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	0.22005417854032144	[312,227]	[251,252]	3	hSpCas9	negative selection	4515735
55547111	55547133	15	+	27760321	OCIAML2	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.3691310542898912	[310,246]	[246,345]	5	hSpCas9	negative selection	4515736
55546671	55546693	15	+	27760321	MV411	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-2.111310497858512	[226,219]	[36,29]	-8	hSpCas9	negative selection	4599195
55546835	55546857	15	+	27760321	MV411	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.11662147221796659	[236,158]	[182,74]	0	hSpCas9	negative selection	4599196
55546859	55546881	15	+	27760321	MV411	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.5537788099021477	[361,347]	[170,604]	4	hSpCas9	negative selection	4599197
55547009	55547031	15	+	27760321	MV411	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.7853051461325312	[312,227]	[74,143]	-5	hSpCas9	negative selection	4599198
55547111	55547133	15	+	27760321	MV411	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	1.0019782146190428	[310,246]	[449,240]	7	hSpCas9	negative selection	4599199
55546671	55546693	15	+	27760321	HL60	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.7473510074569001	[226,219]	[74,144]	-6	hSpCas9	negative selection	4682658
55546835	55546857	15	+	27760321	HL60	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	1.2110572188300563	[236,158]	[356,382]	9	hSpCas9	negative selection	4682659
55546859	55546881	15	+	27760321	HL60	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.4885739301385116	[361,347]	[342,475]	6	hSpCas9	negative selection	4682660
55547009	55547031	15	+	27760321	HL60	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	0.042881807604855604	[312,227]	[206,244]	0	hSpCas9	negative selection	4682661
55547111	55547133	15	+	27760321	HL60	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.6828939953771811	[310,246]	[483,235]	7	hSpCas9	negative selection	4682662
55546671	55546693	15	+	27760321	HT1080	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-2.262747746003368	[219,171]	[21,9]	-6	hSpCas9	negative selection	4766121
55546835	55546857	15	+	27760321	HT1080	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	1.516139993619528	[158,123]	[49,282]	8	hSpCas9	negative selection	4766122
55546859	55546881	15	+	27760321	HT1080	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.7425451827561831	[347,271]	[177,237]	4	hSpCas9	negative selection	4766123
55547009	55547031	15	+	27760321	HT1080	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-1.9946584007917574	[227,177]	[36,1]	-6	hSpCas9	negative selection	4766124
55547111	55547133	15	+	27760321	HT1080	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.5320263156060943	[246,192]	[78,178]	3	hSpCas9	negative selection	4766125
55546671	55546693	15	+	27760321	HT29	viability after 7 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.3555426059413963	[219,171]	[297,171,136]	-5	hSpCas9	negative selection	4849584
55546835	55546857	15	+	27760321	HT29	viability after 7 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.5254452991755663	[158,123]	[367,255,178]	7	hSpCas9	negative selection	4849585
55546859	55546881	15	+	27760321	HT29	viability after 7 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.2044479552704579	[347,271]	[336,319,377]	-3	hSpCas9	negative selection	4849586
55547009	55547031	15	+	27760321	HT29	viability after 7 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.24934329448819648	[227,177]	[339,160,175]	-4	hSpCas9	negative selection	4849587
55547111	55547133	15	+	27760321	HT29	viability after 7 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	-0.04538928245763785	[246,192]	[337,375,121]	0	hSpCas9	negative selection	4849588
55546671	55546693	15	+	27760321	HT29	viability after 25 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	0.3459690745303572	[219,171]	[211,329,319]	3	hSpCas9	negative selection	4933047
55546835	55546857	15	+	27760321	HT29	viability after 25 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	1.3720400973076678	[158,123]	[607,285,340]	9	hSpCas9	negative selection	4933048
55546859	55546881	15	+	27760321	HT29	viability after 25 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.20382221392432975	[347,271]	[370,497,350]	2	hSpCas9	negative selection	4933049
55547009	55547031	15	+	27760321	HT29	viability after 25 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	0.27870723870341707	[227,177]	[139,420,292]	3	hSpCas9	negative selection	4933050
55547111	55547133	15	+	27760321	HT29	viability after 25 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.9988978438278066	[246,192]	[493,512,499]	9	hSpCas9	negative selection	4933051
55546671	55546693	15	+	27760321	HT29	viability after 22 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	0.26589283599405245	[219,171]	[191,310,316]	2	hSpCas9	negative selection	5016510
55546835	55546857	15	+	27760321	HT29	viability after 22 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	1.2238540918970877	[158,123]	[419,356,367]	9	hSpCas9	negative selection	5016511
55546859	55546881	15	+	27760321	HT29	viability after 22 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.19170069343474044	[347,271]	[233,351,357]	-2	hSpCas9	negative selection	5016512
55547009	55547031	15	+	27760321	HT29	viability after 22 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	0.3263500330960858	[227,177]	[172,316,396]	3	hSpCas9	negative selection	5016513
55547111	55547133	15	+	27760321	HT29	viability after 22 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	1.117241216061566	[246,192]	[355,706,597]	9	hSpCas9	negative selection	5016514
55546671	55546693	15	+	27760321	HT29	viability after 19 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	0.11210962032924676	[219,171]	[266,264,198]	1	hSpCas9	negative selection	5099973
55546835	55546857	15	+	27760321	HT29	viability after 19 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.6072633224528236	[158,123]	[441,155,164]	6	hSpCas9	negative selection	5099974
55546859	55546881	15	+	27760321	HT29	viability after 19 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.3505886428997271	[347,271]	[286,311,728]	3	hSpCas9	negative selection	5099975
55547009	55547031	15	+	27760321	HT29	viability after 19 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.41773825716486057	[227,177]	[199,68,251]	-4	hSpCas9	negative selection	5099976
55547111	55547133	15	+	27760321	HT29	viability after 19 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	1.0904218487261348	[246,192]	[481,759,365]	9	hSpCas9	negative selection	5099977
55546671	55546693	15	+	27760321	HT29	viability after 16 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.03745262947990846	[219,171]	[120,185,325]	0	hSpCas9	negative selection	5183436
55546835	55546857	15	+	27760321	HT29	viability after 16 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.6953305888514221	[158,123]	[266,369,129]	7	hSpCas9	negative selection	5183437
55546859	55546881	15	+	27760321	HT29	viability after 16 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.28507815834660144	[347,271]	[461,482,324]	3	hSpCas9	negative selection	5183438
55547009	55547031	15	+	27760321	HT29	viability after 16 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.6515803622451312	[227,177]	[235,119,86]	-6	hSpCas9	negative selection	5183439
55547111	55547133	15	+	27760321	HT29	viability after 16 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.2035278510867352	[246,192]	[338,227,289]	2	hSpCas9	negative selection	5183440
55546671	55546693	15	+	27760321	HT29	viability after 13 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.23435114142035685	[219,171]	[231,208,141]	-3	hSpCas9	negative selection	5266899
55546835	55546857	15	+	27760321	HT29	viability after 13 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.9405122470958069	[158,123]	[357,289,297]	9	hSpCas9	negative selection	5266900
55546859	55546881	15	+	27760321	HT29	viability after 13 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.14965567913349093	[347,271]	[305,245,414]	-2	hSpCas9	negative selection	5266901
55547009	55547031	15	+	27760321	HT29	viability after 13 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.5083484850422598	[227,177]	[144,207,144]	-5	hSpCas9	negative selection	5266902
55547111	55547133	15	+	27760321	HT29	viability after 13 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.5660663540641246	[246,192]	[404,341,385]	7	hSpCas9	negative selection	5266903
55546671	55546693	15	+	27760321	HT29	viability after 10 days	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.1586658459599678	[219,171]	[301,307,53]	-2	hSpCas9	negative selection	5350362
55546835	55546857	15	+	27760321	HT29	viability after 10 days	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	0.7760308328498934	[158,123]	[445,147,308]	9	hSpCas9	negative selection	5350363
55546859	55546881	15	+	27760321	HT29	viability after 10 days	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	-0.1897911460802249	[347,271]	[413,404,203]	-2	hSpCas9	negative selection	5350364
55547009	55547031	15	+	27760321	HT29	viability after 10 days	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.33864546177441734	[227,177]	[253,110,232]	-4	hSpCas9	negative selection	5350365
55547111	55547133	15	+	27760321	HT29	viability after 10 days	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.6875692786889788	[246,192]	[429,503,395]	8	hSpCas9	negative selection	5350366
55546671	55546693	15	+	27760321	MOLM13	viability	AAAATTAGATGCCAAATCGGGG	PYGO1	ENSG00000171016	-0.14392041828928703	[226,219]	[1,209]	-1	hSpCas9	negative selection	5433825
55546835	55546857	15	+	27760321	MOLM13	viability	GCCCAAAGTTAAAAGCATGAGG	PYGO1	ENSG00000171016	-0.6541397566657257	[236,158]	[95,47]	-4	hSpCas9	negative selection	5433826
55546859	55546881	15	+	27760321	MOLM13	viability	GATTAAAACCCATGCCCAGAGG	PYGO1	ENSG00000171016	0.9555539233338638	[361,347]	[145,595]	6	hSpCas9	negative selection	5433827
55547009	55547031	15	+	27760321	MOLM13	viability	CAAGATATGGATTTGACGAAGG	PYGO1	ENSG00000171016	-0.8083367892586869	[312,227]	[182,3]	-5	hSpCas9	negative selection	5433828
55547111	55547133	15	+	27760321	MOLM13	viability	GTGGAGCATACTCAGACAATGG	PYGO1	ENSG00000171016	0.37398021810635557	[310,246]	[64,319]	2	hSpCas9	negative selection	5433829
55546682	55546705	15	-	27260156	BXPC3	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.26186403764798316	[702]	[829,804,871,1041]	6	hSpCas9	negative selection	5565785
55546058	55546081	15	+	27260156	BXPC3	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.07745083799178043	[1150]	[1025,1104,999,1476]	-2	hSpCas9	negative selection	5565786
55588803	55588826	15	-	27260156	BXPC3	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.25945579106390326	[692]	[712,862,969,945]	5	hSpCas9	negative selection	5565787
55548921	55548944	15	-	27260156	BXPC3	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.03825091012710613	[562]	[600,494,685,644]	0	hSpCas9	negative selection	5630043
55588805	55588828	15	+	27260156	BXPC3	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.17734371296318208	[316]	[349,278,373,519]	4	hSpCas9	negative selection	5630044
55548959	55548982	15	-	27260156	BXPC3	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.16996748998528322	[461]	[629,328,512,722]	4	hSpCas9	negative selection	5630045
55546682	55546705	15	-	27260156	A673	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.2577322106292743	[702]	[1027,952,1049,1006]	6	hSpCas9	negative selection	5687036
55546058	55546081	15	+	27260156	A673	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.02046079881713392	[1150]	[1406,1325,1309,1413]	0	hSpCas9	negative selection	5687037
55588803	55588826	15	-	27260156	A673	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.18239848821099724	[692]	[1082,960,656,1100]	4	hSpCas9	negative selection	5687038
55548921	55548944	15	-	27260156	A673	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.03824173383344137	[562]	[797,548,646,656]	-1	hSpCas9	negative selection	5751294
55588805	55588828	15	+	27260156	A673	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.04601549667374494	[316]	[380,410,417,356]	1	hSpCas9	negative selection	5751295
55548959	55548982	15	-	27260156	A673	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.19974218529636434	[461]	[650,578,680,638]	5	hSpCas9	negative selection	5751296
55546682	55546705	15	-	27260156	A375	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.10631259814084193	[702]	[1194,972,607,782]	1	hSpCas9	negative selection	5808287
55546058	55546081	15	+	27260156	A375	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.4655741797152584	[1150]	[2001,2108,1750,1620]	6	hSpCas9	negative selection	5808288
55588803	55588826	15	-	27260156	A375	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	-0.0632122597958511	[692]	[581,834,764,904]	-1	hSpCas9	negative selection	5808289
55548921	55548944	15	-	27260156	A375	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.05094256089725596	[562]	[659,843,617,628]	0	hSpCas9	negative selection	5872545
55588805	55588828	15	+	27260156	A375	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.0956977790010487	[316]	[355,416,389,417]	1	hSpCas9	negative selection	5872546
55548959	55548982	15	-	27260156	A375	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.016708772286929297	[461]	[455,524,598,547]	0	hSpCas9	negative selection	5872547
55546682	55546705	15	-	27260156	COLO741	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.03475454996522276	[702]	[967,925,871]	0	hSpCas9	negative selection	5929538
55546058	55546081	15	+	27260156	COLO741	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.15057153952786306	[1150]	[1522,1361,1118]	-3	hSpCas9	negative selection	5929539
55588803	55588826	15	-	27260156	COLO741	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.35021754428759	[692]	[1160,1105,1119]	7	hSpCas9	negative selection	5929540
55548921	55548944	15	-	27260156	COLO741	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.4661222451661923	[562]	[623,527,424]	-7	hSpCas9	negative selection	5993796
55588805	55588828	15	+	27260156	COLO741	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.0034802009198049433	[316]	[419,463,333]	0	hSpCas9	negative selection	5993797
55548959	55548982	15	-	27260156	COLO741	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.24079042636189035	[461]	[776,628,691]	5	hSpCas9	negative selection	5993798
55546682	55546705	15	-	27260156	CAL120	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.4765330428965985	[702]	[1660,1014,1044]	7	hSpCas9	negative selection	6050789
55546058	55546081	15	+	27260156	CAL120	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.35704548599760133	[1150]	[2211,1933,1420]	5	hSpCas9	negative selection	6050790
55588803	55588826	15	-	27260156	CAL120	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.2333420055572495	[692]	[1481,934,699]	3	hSpCas9	negative selection	6050791
55548921	55548944	15	-	27260156	CAL120	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.006003291881532147	[562]	[598,818,676]	0	hSpCas9	negative selection	6115047
55588805	55588828	15	+	27260156	CAL120	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.013041322092773311	[316]	[505,348,355]	0	hSpCas9	negative selection	6115048
55548959	55548982	15	-	27260156	CAL120	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.20842221995438648	[461]	[547,504,447]	-3	hSpCas9	negative selection	6115049
55546682	55546705	15	-	27260156	CADOES1	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.32589587321569946	[702]	[1041,837,671,721]	5	hSpCas9	negative selection	6172040
55546058	55546081	15	+	27260156	CADOES1	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.17165253506060774	[1150]	[1108,1246,1167,1302]	3	hSpCas9	negative selection	6172041
55588803	55588826	15	-	27260156	CADOES1	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.22995407412940572	[692]	[799,645,776,801]	4	hSpCas9	negative selection	6172042
55548921	55548944	15	-	27260156	CADOES1	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.07984551908323267	[562]	[596,638,494,479]	1	hSpCas9	negative selection	6236298
55588805	55588828	15	+	27260156	CADOES1	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.23676401515759526	[316]	[277,260,205,255]	-4	hSpCas9	negative selection	6236299
55548959	55548982	15	-	27260156	CADOES1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.35171310966559405	[461]	[650,465,522,552]	6	hSpCas9	negative selection	6236300
55546682	55546705	15	-	27260156	EWS502	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.4844867197664654	[702]	[827,1034,1233,1098]	8	hSpCas9	negative selection	6293291
55546058	55546081	15	+	27260156	EWS502	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.09847278589715458	[1150]	[1369,1256,1157,1431]	1	hSpCas9	negative selection	6293292
55588803	55588826	15	-	27260156	EWS502	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.42425488782873233	[692]	[1089,898,972,962]	7	hSpCas9	negative selection	6293293
55548921	55548944	15	-	27260156	EWS502	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.09476819401259809	[562]	[576,495,557,603]	-2	hSpCas9	negative selection	6357549
55588805	55588828	15	+	27260156	EWS502	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.17701615566383888	[316]	[362,460,288,402]	3	hSpCas9	negative selection	6357550
55548959	55548982	15	-	27260156	EWS502	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.10350400108229972	[461]	[485,551,522,544]	1	hSpCas9	negative selection	6357551
55546682	55546705	15	-	27260156	EW8	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.430107067107418	[702]	[762,647,771,882]	7	hSpCas9	negative selection	6414542
55546058	55546081	15	+	27260156	EW8	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.015265667984033282	[1150]	[888,1072,913,811]	0	hSpCas9	negative selection	6414543
55588803	55588826	15	-	27260156	EW8	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.11180933793834924	[692]	[509,701,525,690]	2	hSpCas9	negative selection	6414544
55548921	55548944	15	-	27260156	EW8	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.1313069766440255	[562]	[397,429,332,515]	-2	hSpCas9	negative selection	6478800
55588805	55588828	15	+	27260156	EW8	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.1009869283719732	[316]	[199,356,205,341]	1	hSpCas9	negative selection	6478801
55548959	55548982	15	-	27260156	EW8	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.2825603191427731	[461]	[437,441,318,641]	5	hSpCas9	negative selection	6478802
55546682	55546705	15	-	27260156	CORL105	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.12899952373183765	[702]	[803,952,1030,827]	2	hSpCas9	negative selection	6535793
55546058	55546081	15	+	27260156	CORL105	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.11998366358522938	[1150]	[1368,1220,2052,1307]	2	hSpCas9	negative selection	6535794
55588803	55588826	15	-	27260156	CORL105	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.3791488092448271	[692]	[1130,972,1252,898]	7	hSpCas9	negative selection	6535795
55548921	55548944	15	-	27260156	CORL105	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.09351635420689206	[562]	[657,756,660,400]	-2	hSpCas9	negative selection	6600051
55588805	55588828	15	+	27260156	CORL105	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.03539533998628219	[316]	[495,385,248,303]	0	hSpCas9	negative selection	6600052
55548959	55548982	15	-	27260156	CORL105	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.033819464816164505	[461]	[475,486,804,387]	0	hSpCas9	negative selection	6600053
55546682	55546705	15	-	27260156	HS294T	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.10475524815065851	[702]	[312,294,255,303]	1	hSpCas9	negative selection	6657044
55546058	55546081	15	+	27260156	HS294T	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.34471752117708854	[1150]	[799,393,425,632]	4	hSpCas9	negative selection	6657045
55588803	55588826	15	-	27260156	HS294T	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.40956886236800405	[692]	[232,320,333,585]	5	hSpCas9	negative selection	6657046
55548921	55548944	15	-	27260156	HS294T	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.10607055053750764	[562]	[177,349,144,270]	1	hSpCas9	negative selection	6721302
55588805	55588828	15	+	27260156	HS294T	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.42507783708344804	[316]	[101,59,100,103]	-6	hSpCas9	negative selection	6721303
55548959	55548982	15	-	27260156	HS294T	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.3222483127050624	[461]	[73,217,135,147]	-4	hSpCas9	negative selection	6721304
55546682	55546705	15	-	27260156	HCC44	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.5394258953682466	[702]	[1175,1423,873,1056]	8	hSpCas9	negative selection	6778295
55546058	55546081	15	+	27260156	HCC44	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.0717542440032104	[1150]	[1452,1145,1320,1565]	1	hSpCas9	negative selection	6778296
55588803	55588826	15	-	27260156	HCC44	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.4702230566836215	[692]	[1244,713,1456,1050]	7	hSpCas9	negative selection	6778297
55548921	55548944	15	-	27260156	HCC44	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.2357229063111498	[562]	[524,412,819,467]	-4	hSpCas9	negative selection	6842553
55588805	55588828	15	+	27260156	HCC44	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.14078117087213382	[316]	[379,263,565,413]	2	hSpCas9	negative selection	6842554
55548959	55548982	15	-	27260156	HCC44	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.14693390211638346	[461]	[758,668,358,490]	2	hSpCas9	negative selection	6842555
55546682	55546705	15	-	27260156	G402	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.682808355100262	[702]	[2086,1404,1038,1089]	8	hSpCas9	negative selection	6899546
55546058	55546081	15	+	27260156	G402	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.30505600646269526	[1150]	[1731,2477,1230,1544]	4	hSpCas9	negative selection	6899547
55588803	55588826	15	-	27260156	G402	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	-0.20978867607505108	[692]	[480,1190,733,516]	-3	hSpCas9	negative selection	6899548
55548921	55548944	15	-	27260156	G402	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.2416932697729263	[562]	[856,455,388,648]	-3	hSpCas9	negative selection	6963804
55588805	55588828	15	+	27260156	G402	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.17447992579327043	[316]	[667,402,439,272]	2	hSpCas9	negative selection	6963805
55548959	55548982	15	-	27260156	G402	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.4146900818006084	[461]	[345,465,459,409]	-5	hSpCas9	negative selection	6963806
55546682	55546705	15	-	27260156	L33	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.43331083200315945	[702]	[801,397,695,920]	8	hSpCas9	negative selection	7020797
55546058	55546081	15	+	27260156	L33	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.08335225915717892	[1150]	[1099,395,696,1168]	-2	hSpCas9	negative selection	7020798
55588803	55588826	15	-	27260156	L33	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.4330538194982164	[692]	[802,391,621,995]	8	hSpCas9	negative selection	7020799
55548921	55548944	15	-	27260156	L33	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.12527853384066748	[562]	[497,249,267,529]	-3	hSpCas9	negative selection	7085055
55588805	55588828	15	+	27260156	L33	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.2476390211051117	[316]	[252,116,182,238]	-5	hSpCas9	negative selection	7085056
55548959	55548982	15	-	27260156	L33	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.13265310615226283	[461]	[264,257,281,346]	-3	hSpCas9	negative selection	7085057
55546682	55546705	15	-	27260156	K562	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.3707240596788034	[702]	[732,723,686,1040]	5	hSpCas9	negative selection	7142048
55546058	55546081	15	+	27260156	K562	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.02783491653958725	[1150]	[1196,1051,1044,756]	0	hSpCas9	negative selection	7142049
55588803	55588826	15	-	27260156	K562	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.19265491928596779	[692]	[619,479,1336,389]	2	hSpCas9	negative selection	7142050
55548921	55548944	15	-	27260156	K562	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.16181438218394917	[562]	[420,495,505,370]	-2	hSpCas9	negative selection	7206306
55588805	55588828	15	+	27260156	K562	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.3063790030142456	[316]	[448,250,138,103]	-4	hSpCas9	negative selection	7206307
55548959	55548982	15	-	27260156	K562	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.22719689346182403	[461]	[273,431,335,354]	-3	hSpCas9	negative selection	7206308
55546682	55546705	15	-	27260156	HT29	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.37490244967682573	[702]	[1255,1357,991,879]	7	hSpCas9	negative selection	7263299
55546058	55546081	15	+	27260156	HT29	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.15098339991870202	[1150]	[1517,1588,1747,1370]	3	hSpCas9	negative selection	7263300
55588803	55588826	15	-	27260156	HT29	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.42047938668784535	[692]	[1315,1043,1263,911]	7	hSpCas9	negative selection	7263301
55548921	55548944	15	-	27260156	HT29	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.03913212249856579	[562]	[655,817,650,559]	-1	hSpCas9	negative selection	7327557
55588805	55588828	15	+	27260156	HT29	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.179887460148057	[316]	[323,428,301,312]	-4	hSpCas9	negative selection	7327558
55548959	55548982	15	-	27260156	HT29	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.1141159589127419	[461]	[633,562,484,727]	2	hSpCas9	negative selection	7327559
55546682	55546705	15	-	27260156	MHHES1	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.14900532418872459	[702]	[906,1124,820,706]	2	hSpCas9	negative selection	7384550
55546058	55546081	15	+	27260156	MHHES1	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.3052393514768621	[1150]	[1668,1706,1610,1439]	5	hSpCas9	negative selection	7384551
55588803	55588826	15	-	27260156	MHHES1	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.24685736486090404	[692]	[796,977,1037,872]	4	hSpCas9	negative selection	7384552
55548921	55548944	15	-	27260156	MHHES1	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.053338896798521385	[562]	[575,962,716,434]	1	hSpCas9	negative selection	7448808
55588805	55588828	15	+	27260156	MHHES1	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.07719319513461442	[316]	[357,467,461,247]	1	hSpCas9	negative selection	7448809
55548959	55548982	15	-	27260156	MHHES1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.07698944119426597	[461]	[417,563,647,361]	-1	hSpCas9	negative selection	7448810
55546682	55546705	15	-	27260156	MEWO	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.3207838948420819	[702]	[1085,715,713]	7	hSpCas9	negative selection	7505801
55546058	55546081	15	+	27260156	MEWO	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.0387181705467019	[1150]	[1401,991,981]	0	hSpCas9	negative selection	7505802
55588803	55588826	15	-	27260156	MEWO	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.22254781212051955	[692]	[1005,678,632]	5	hSpCas9	negative selection	7505803
55548921	55548944	15	-	27260156	MEWO	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.17906261344953747	[562]	[522,425,457]	-4	hSpCas9	negative selection	7570059
55588805	55588828	15	+	27260156	MEWO	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.024600418104314237	[316]	[187,403,261]	0	hSpCas9	negative selection	7570060
55548959	55548982	15	-	27260156	MEWO	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.4767076309557124	[461]	[746,495,589]	8	hSpCas9	negative selection	7570061
55546682	55546705	15	-	27260156	LNCAPCLONEFGC	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.4428374216842387	[702]	[980,901,924,657]	7	hSpCas9	negative selection	7627052
55546058	55546081	15	+	27260156	LNCAPCLONEFGC	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.02209169419049828	[1150]	[964,876,1224,1079]	0	hSpCas9	negative selection	7627053
55588803	55588826	15	-	27260156	LNCAPCLONEFGC	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.21060228869790332	[692]	[642,643,946,710]	3	hSpCas9	negative selection	7627054
55548921	55548944	15	-	27260156	LNCAPCLONEFGC	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.13868753071355705	[562]	[641,491,746,394]	2	hSpCas9	negative selection	7691310
55588805	55588828	15	+	27260156	LNCAPCLONEFGC	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.1761491726759435	[316]	[271,391,417,225]	2	hSpCas9	negative selection	7691311
55548959	55548982	15	-	27260156	LNCAPCLONEFGC	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.08202299468745643	[461]	[450,390,402,523]	1	hSpCas9	negative selection	7691312
55546682	55546705	15	-	27260156	PANC0327	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.6835564011410041	[702]	[924,717,1963,436]	8	hSpCas9	negative selection	7748303
55546058	55546081	15	+	27260156	PANC0327	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.29678311009792746	[1150]	[1333,937,1780,1018]	4	hSpCas9	negative selection	7748304
55588803	55588826	15	-	27260156	PANC0327	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.31706774756598943	[692]	[802,780,522,960]	5	hSpCas9	negative selection	7748305
55548921	55548944	15	-	27260156	PANC0327	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.24661945397232576	[562]	[485,720,603,536]	3	hSpCas9	negative selection	7812561
55588805	55588828	15	+	27260156	PANC0327	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.5295260881775686	[316]	[446,283,484,428]	7	hSpCas9	negative selection	7812562
55548959	55548982	15	-	27260156	PANC0327	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.27777794354573737	[461]	[544,304,654,513]	4	hSpCas9	negative selection	7812563
55546682	55546705	15	-	27260156	NCIH2009	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.4966110730614294	[702]	[1337,1305,1502]	6	hSpCas9	negative selection	7869554
55546058	55546081	15	+	27260156	NCIH2009	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.1664190498801037	[1150]	[2003,1560,1889]	2	hSpCas9	negative selection	7869555
55588803	55588826	15	-	27260156	NCIH2009	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.16269610113295407	[692]	[1298,925,1069]	2	hSpCas9	negative selection	7869556
55548921	55548944	15	-	27260156	NCIH2009	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.5054102883937741	[562]	[816,1043,1428]	7	hSpCas9	negative selection	7933812
55588805	55588828	15	+	27260156	NCIH2009	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.3158011411660434	[316]	[323,332,403]	-4	hSpCas9	negative selection	7933813
55548959	55548982	15	-	27260156	NCIH2009	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.4091271690843168	[461]	[867,318,348]	-5	hSpCas9	negative selection	7933814
55546682	55546705	15	-	27260156	NCIH1373	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.6659769568320414	[702]	[1703,1043,1097,326]	6	hSpCas9	negative selection	7990805
55546058	55546081	15	+	27260156	NCIH1373	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.9379221073031492	[1150]	[2625,2430,2610,581]	8	hSpCas9	negative selection	7990806
55588803	55588826	15	-	27260156	NCIH1373	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.2807001456103463	[692]	[1183,976,776,226]	2	hSpCas9	negative selection	7990807
55548921	55548944	15	-	27260156	NCIH1373	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.01445868672063294	[562]	[684,299,700,227]	0	hSpCas9	negative selection	8055063
55588805	55588828	15	+	27260156	NCIH1373	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.29675982353112573	[316]	[143,242,163,159]	-3	hSpCas9	negative selection	8055064
55548959	55548982	15	-	27260156	NCIH1373	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.7580661056936863	[461]	[236,178,392,110]	-6	hSpCas9	negative selection	8055065
55546682	55546705	15	-	27260156	PATU8902	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.2284345113363172	[702]	[1529,1283,772,1075]	2	hSpCas9	negative selection	8112056
55546058	55546081	15	+	27260156	PATU8902	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.4463739731931142	[1150]	[2238,2449,1482,2803]	4	hSpCas9	negative selection	8112057
55588803	55588826	15	-	27260156	PATU8902	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.15825651897231852	[692]	[1147,961,788,1527]	1	hSpCas9	negative selection	8112058
55548921	55548944	15	-	27260156	PATU8902	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.43681966593480626	[562]	[900,1214,1282,744]	4	hSpCas9	negative selection	8176314
55588805	55588828	15	+	27260156	PATU8902	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.2514373603238547	[316]	[358,243,466,1114]	2	hSpCas9	negative selection	8176315
55548959	55548982	15	-	27260156	PATU8902	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.3596632274622846	[461]	[1052,619,650,1038]	3	hSpCas9	negative selection	8176316
55546682	55546705	15	-	27260156	PANC1	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.4371471145136231	[702]	[777,1076,735,732]	7	hSpCas9	negative selection	8233307
55546058	55546081	15	+	27260156	PANC1	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.28194784462823885	[1150]	[1607,1325,1088,840]	4	hSpCas9	negative selection	8233308
55588803	55588826	15	-	27260156	PANC1	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.6516157531394519	[692]	[847,1293,1042,661]	9	hSpCas9	negative selection	8233309
55548921	55548944	15	-	27260156	PANC1	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.05084957586148564	[562]	[490,576,589,374]	0	hSpCas9	negative selection	8297565
55588805	55588828	15	+	27260156	PANC1	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.38405325098144727	[316]	[352,406,365,307]	6	hSpCas9	negative selection	8297566
55548959	55548982	15	-	27260156	PANC1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.003973728162596911	[461]	[302,436,387,456]	0	hSpCas9	negative selection	8297567
55546682	55546705	15	-	27260156	PANC0813	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.2757111096150404	[702]	[1215,1097,812,894]	4	hSpCas9	negative selection	8354558
55546058	55546081	15	+	27260156	PANC0813	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.2493512692826394	[1150]	[1820,1518,1874,1251]	4	hSpCas9	negative selection	8354559
55588803	55588826	15	-	27260156	PANC0813	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.6427764057099691	[692]	[1132,1171,1491,1272]	8	hSpCas9	negative selection	8354560
55548921	55548944	15	-	27260156	PANC0813	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.25877800387101707	[562]	[768,389,587,486]	-4	hSpCas9	negative selection	8418816
55588805	55588828	15	+	27260156	PANC0813	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.008640954955881353	[316]	[338,316,327,502]	0	hSpCas9	negative selection	8418817
55548959	55548982	15	-	27260156	PANC0813	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.07074885082951245	[461]	[558,470,643,402]	-1	hSpCas9	negative selection	8418818
55546682	55546705	15	-	27260156	RDES	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.32130620916771124	[702]	[866,800,1196,1237]	5	hSpCas9	negative selection	8475809
55546058	55546081	15	+	27260156	RDES	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.18123629927655438	[1150]	[1144,1281,1833,1865]	3	hSpCas9	negative selection	8475810
55588803	55588826	15	-	27260156	RDES	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.2721861926383897	[692]	[901,941,1072,911]	4	hSpCas9	negative selection	8475811
55548921	55548944	15	-	27260156	RDES	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.08355261427995053	[562]	[466,607,795,954]	1	hSpCas9	negative selection	8540067
55588805	55588828	15	+	27260156	RDES	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.013931426105914912	[316]	[271,440,444,310]	0	hSpCas9	negative selection	8540068
55548959	55548982	15	-	27260156	RDES	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.030197617880875494	[461]	[493,547,509,620]	0	hSpCas9	negative selection	8540069
55546682	55546705	15	-	27260156	PC3	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.41455921778645033	[702]	[776,825,1253,961]	8	hSpCas9	negative selection	8597060
55546058	55546081	15	+	27260156	PC3	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.07700801857858353	[1150]	[593,1213,1908,1066]	-2	hSpCas9	negative selection	8597061
55588803	55588826	15	-	27260156	PC3	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.31074313792257524	[692]	[575,1025,1164,799]	6	hSpCas9	negative selection	8597062
55548921	55548944	15	-	27260156	PC3	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.1303103367229601	[562]	[339,462,922,510]	-3	hSpCas9	negative selection	8661318
55588805	55588828	15	+	27260156	PC3	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.2866364740969569	[316]	[186,244,490,204]	-6	hSpCas9	negative selection	8661319
55548959	55548982	15	-	27260156	PC3	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.19599857579457952	[461]	[349,483,826,594]	4	hSpCas9	negative selection	8661320
55546682	55546705	15	-	27260156	PATU8988T	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.381589526289526	[702]	[1405,748,448,932]	6	hSpCas9	negative selection	8718311
55546058	55546081	15	+	27260156	PATU8988T	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.12888708780691016	[1150]	[989,1190,863,1043]	-2	hSpCas9	negative selection	8718312
55588803	55588826	15	-	27260156	PATU8988T	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.23810648753876296	[692]	[633,946,544,1073]	4	hSpCas9	negative selection	8718313
55548921	55548944	15	-	27260156	PATU8988T	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.3512119867014732	[562]	[409,624,251,440]	-5	hSpCas9	negative selection	8782569
55588805	55588828	15	+	27260156	PATU8988T	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.07335405872021239	[316]	[270,231,323,334]	-1	hSpCas9	negative selection	8782570
55548959	55548982	15	-	27260156	PATU8988T	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.26515774590099384	[461]	[383,741,557,475]	4	hSpCas9	negative selection	8782571
55546682	55546705	15	-	27260156	T47D	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.309691251104276	[702]	[1131,936,958,1040]	6	hSpCas9	negative selection	8839562
55546058	55546081	15	+	27260156	T47D	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.04446582478955019	[1150]	[1424,1208,1426,1487]	0	hSpCas9	negative selection	8839563
55588803	55588826	15	-	27260156	T47D	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.536745510372299	[692]	[1275,1000,1136,1289]	9	hSpCas9	negative selection	8839564
55548921	55548944	15	-	27260156	T47D	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.037212661065144315	[562]	[637,635,579,847]	0	hSpCas9	negative selection	8903820
55588805	55588828	15	+	27260156	T47D	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.07163440419621753	[316]	[460,328,315,454]	1	hSpCas9	negative selection	8903821
55548959	55548982	15	-	27260156	T47D	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.20024968784341418	[461]	[590,581,607,697]	4	hSpCas9	negative selection	8903822
55546682	55546705	15	-	27260156	SU8686	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.5150603706906282	[702]	[999,927,980,1090]	8	hSpCas9	negative selection	8960813
55546058	55546081	15	+	27260156	SU8686	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.24969535738035398	[1150]	[1040,1261,1390,1852]	4	hSpCas9	negative selection	8960814
55588803	55588826	15	-	27260156	SU8686	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.08959306549387758	[692]	[717,738,620,858]	1	hSpCas9	negative selection	8960815
55548921	55548944	15	-	27260156	SU8686	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.0540236090133715	[562]	[547,533,491,576]	-1	hSpCas9	negative selection	9025071
55588805	55588828	15	+	27260156	SU8686	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.028458231298606362	[316]	[336,211,232,483]	0	hSpCas9	negative selection	9025072
55548959	55548982	15	-	27260156	SU8686	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.15652744443121286	[461]	[251,361,527,548]	-3	hSpCas9	negative selection	9025073
55546682	55546705	15	-	27260156	SKES1	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.2628345934745795	[702]	[1043,866,777,714]	5	hSpCas9	negative selection	9082064
55546058	55546081	15	+	27260156	SKES1	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.17763038267607145	[1150]	[1107,1157,814,1002]	-4	hSpCas9	negative selection	9082065
55588803	55588826	15	-	27260156	SKES1	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.19568294341672365	[692]	[954,822,698,717]	4	hSpCas9	negative selection	9082066
55548921	55548944	15	-	27260156	SKES1	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.055681827723086275	[562]	[456,442,696,533]	-1	hSpCas9	negative selection	9146322
55588805	55588828	15	+	27260156	SKES1	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.02467860994208082	[316]	[297,372,277,335]	0	hSpCas9	negative selection	9146323
55548959	55548982	15	-	27260156	SKES1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.16668578098089115	[461]	[590,560,456,475]	3	hSpCas9	negative selection	9146324
55546682	55546705	15	-	27260156	TOV112D	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.46944173729709526	[702]	[1046,1267,792,870]	8	hSpCas9	negative selection	9203315
55546058	55546081	15	+	27260156	TOV112D	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.027899588603284453	[1150]	[1024,1477,1198,901]	0	hSpCas9	negative selection	9203316
55588803	55588826	15	-	27260156	TOV112D	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.07063942712491156	[692]	[641,823,898,569]	1	hSpCas9	negative selection	9203317
55548921	55548944	15	-	27260156	TOV112D	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.3184658014489442	[562]	[372,608,517,342]	-6	hSpCas9	negative selection	9267573
55588805	55588828	15	+	27260156	TOV112D	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.10016531877716572	[316]	[351,561,297,207]	2	hSpCas9	negative selection	9267574
55548959	55548982	15	-	27260156	TOV112D	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.37053608083118555	[461]	[460,698,678,566]	7	hSpCas9	negative selection	9267575
55546682	55546705	15	-	27260156	TC71	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.3960664492203444	[702]	[916,1024,1010,1015]	8	hSpCas9	negative selection	9324566
55546058	55546081	15	+	27260156	TC71	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	-0.02161961836665327	[1150]	[1073,1295,1215,1282]	0	hSpCas9	negative selection	9324567
55588803	55588826	15	-	27260156	TC71	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.16075202562693014	[692]	[862,791,871,789]	4	hSpCas9	negative selection	9324568
55548921	55548944	15	-	27260156	TC71	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	-0.1685632801749136	[562]	[558,469,498,625]	-4	hSpCas9	negative selection	9388824
55588805	55588828	15	+	27260156	TC71	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	-0.03616558472191567	[316]	[439,271,268,344]	-1	hSpCas9	negative selection	9388825
55548959	55548982	15	-	27260156	TC71	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.12019966255883853	[461]	[526,654,511,454]	3	hSpCas9	negative selection	9388826
55546682	55546705	15	-	27260156	TC32	viability	CCAAGTTTCTAACCCCGATTTGG	PYGO1	ENSG00000171016	0.3131951086595631	[702]	[573,833,1060,830]	5	hSpCas9	negative selection	9445817
55546058	55546081	15	+	27260156	TC32	viability	TTTCTCTAGTACGCATTAACTGG	PYGO1	ENSG00000171016	0.2781500819177172	[1150]	[1134,1327,1422,1309]	5	hSpCas9	negative selection	9445818
55588803	55588826	15	-	27260156	TC32	viability	GCTTACAAAGTTTCCTCGCATGG	PYGO1	ENSG00000171016	0.24138215558624643	[692]	[623,571,1052,937]	4	hSpCas9	negative selection	9445819
55548921	55548944	15	-	27260156	TC32	viability	CCCAGATAAGAAAAAGCGCAAGG	PYGO1	ENSG00000171016	0.016050513891265716	[562]	[500,485,487,651]	0	hSpCas9	negative selection	9510075
55588805	55588828	15	+	27260156	TC32	viability	ATGCGAGGAAACTTTGTAAGCGG	PYGO1	ENSG00000171016	0.01895133444906072	[316]	[293,245,295,377]	0	hSpCas9	negative selection	9510076
55548959	55548982	15	-	27260156	TC32	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.0862377046733974	[461]	[342,218,566,603]	-1	hSpCas9	negative selection	9510077
55546262	55546285	15	+	27869803	HPAFII	viability after 27 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.014516091146984156	[321]	[230,120,NaN]	0	hSpCas9	negative selection	9554070
55546984	55547007	15	+	27869803	HPAFII	viability after 27 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.213638502211151	[404]	[217,270,NaN]	1	hSpCas9	negative selection	9554071
55548909	55548932	15	-	27869803	HPAFII	viability after 27 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.08540087441606792	[404]	[142,294,NaN]	0	hSpCas9	negative selection	9554072
55548941	55548964	15	+	27869803	HPAFII	viability after 27 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	1.5110081729937201	[113]	[196,148,NaN]	9	hSpCas9	negative selection	9554073
55587836	55587859	15	+	27869803	HPAFII	viability after 27 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.8432971264518747	[478]	[549,369,NaN]	6	hSpCas9	negative selection	9554074
55588812	55588835	15	+	27869803	HPAFII	viability after 27 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.8352433077115284	[57]	[13,3,NaN]	-8	hSpCas9	negative selection	9554075
55546262	55546285	15	+	27869803	HPAFII	viability after 15 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.2416328812393102	[321]	[521,338,NaN]	2	hSpCas9	negative selection	9636519
55546984	55547007	15	+	27869803	HPAFII	viability after 15 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.5337226430358015	[404]	[803,521,NaN]	6	hSpCas9	negative selection	9636520
55548909	55548932	15	-	27869803	HPAFII	viability after 15 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.4401966244353354	[404]	[379,283,NaN]	-5	hSpCas9	negative selection	9636521
55548941	55548964	15	+	27869803	HPAFII	viability after 15 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	1.792744436485594	[113]	[561,338,NaN]	9	hSpCas9	negative selection	9636522
55587836	55587859	15	+	27869803	HPAFII	viability after 15 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.6620368021425138	[478]	[1186,582,NaN]	7	hSpCas9	negative selection	9636523
55588812	55588835	15	+	27869803	HPAFII	viability after 15 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.211511642139775	[57]	[29,24,NaN]	-8	hSpCas9	negative selection	9636524
55546262	55546285	15	+	27869803	ASPC1	viability after 36 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.44625720914512396	[656]	[193,265,70]	-4	hSpCas9	negative selection	9718968
55546984	55547007	15	+	27869803	ASPC1	viability after 36 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.32320039184828103	[860]	[521,265,356]	3	hSpCas9	negative selection	9718969
55548909	55548932	15	-	27869803	ASPC1	viability after 36 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.5117076511659107	[871]	[665,362,322]	5	hSpCas9	negative selection	9718970
55548941	55548964	15	+	27869803	ASPC1	viability after 36 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.4857893781158381	[355]	[207,210,118]	5	hSpCas9	negative selection	9718971
55587836	55587859	15	+	27869803	ASPC1	viability after 36 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.3527700874669695	[1196]	[634,516,469]	3	hSpCas9	negative selection	9718972
55588812	55588835	15	+	27869803	ASPC1	viability after 36 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.1273135194932138	[242]	[88,74,70]	-1	hSpCas9	negative selection	9718973
55546262	55546285	15	+	27869803	PATU8988S	viability after 35 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.9408389449804825	[667]	[496,535,NaN]	8	hSpCas9	negative selection	9801417
55546984	55547007	15	+	27869803	PATU8988S	viability after 35 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.2914884839213423	[708]	[342,355,NaN]	3	hSpCas9	negative selection	9801418
55548909	55548932	15	-	27869803	PATU8988S	viability after 35 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.29640487810955407	[711]	[233,232,NaN]	-3	hSpCas9	negative selection	9801419
55548941	55548964	15	+	27869803	PATU8988S	viability after 35 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	-0.07653332013922531	[292]	[71,151,NaN]	-1	hSpCas9	negative selection	9801420
55587836	55587859	15	+	27869803	PATU8988S	viability after 35 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.6122811184143091	[1085]	[721,614,NaN]	6	hSpCas9	negative selection	9801421
55588812	55588835	15	+	27869803	PATU8988S	viability after 35 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.5185249514996297	[181]	[105,103,NaN]	6	hSpCas9	negative selection	9801422
55546262	55546285	15	+	27869803	PATU8988S	viability after 31 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.5828766445789195	[667]	[416,375,NaN]	7	hSpCas9	negative selection	9883866
55546984	55547007	15	+	27869803	PATU8988S	viability after 31 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.2897601699194653	[708]	[316,381,NaN]	3	hSpCas9	negative selection	9883867
55548909	55548932	15	-	27869803	PATU8988S	viability after 31 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.16242451157489723	[711]	[232,279,NaN]	-2	hSpCas9	negative selection	9883868
55548941	55548964	15	+	27869803	PATU8988S	viability after 31 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	0.059065035195990157	[292]	[93,156,NaN]	0	hSpCas9	negative selection	9883869
55587836	55587859	15	+	27869803	PATU8988S	viability after 31 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	0.45522871857068226	[1085]	[649,521,NaN]	5	hSpCas9	negative selection	9883870
55588812	55588835	15	+	27869803	PATU8988S	viability after 31 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.15890930710078122	[181]	[75,50,NaN]	-2	hSpCas9	negative selection	9883871
55546262	55546285	15	+	27869803	HPAFII	viability after 35 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	0.16880216513855834	[321]	[202,160,NaN]	1	hSpCas9	negative selection	9966315
55546984	55547007	15	+	27869803	HPAFII	viability after 35 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	0.10896109305916113	[404]	[214,227,NaN]	0	hSpCas9	negative selection	9966316
55548909	55548932	15	-	27869803	HPAFII	viability after 35 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.18815328056306058	[404]	[99,269,NaN]	-1	hSpCas9	negative selection	9966317
55548941	55548964	15	+	27869803	HPAFII	viability after 35 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	2.486106368452541	[113]	[296,352,NaN]	9	hSpCas9	negative selection	9966318
55587836	55587859	15	+	27869803	HPAFII	viability after 35 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.1627945452596413	[478]	[612,463,NaN]	7	hSpCas9	negative selection	9966319
55588812	55588835	15	+	27869803	HPAFII	viability after 35 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.11741903042406	[57]	[21,3,NaN]	-6	hSpCas9	negative selection	9966320
55546262	55546285	15	+	27869803	HPAFII	viability after 31 days	ACACTGGGTCAGAAGACGAATGG	PYGO1	ENSG00000171016	-0.12685827163214167	[321]	[198,128,NaN]	-1	hSpCas9	negative selection	10048764
55546984	55547007	15	+	27869803	HPAFII	viability after 31 days	CCTCCAAAGCCAGGATAACCAGG	PYGO1	ENSG00000171016	-0.036081389573167866	[404]	[180,265,NaN]	0	hSpCas9	negative selection	10048765
55548909	55548932	15	-	27869803	HPAFII	viability after 31 days	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.15422005024929053	[404]	[150,363,NaN]	1	hSpCas9	negative selection	10048766
55548941	55548964	15	+	27869803	HPAFII	viability after 31 days	GGGCTTCCTAGTTGTACACCTGG	PYGO1	ENSG00000171016	2.2745431243278613	[113]	[321,295,NaN]	9	hSpCas9	negative selection	10048767
55587836	55587859	15	+	27869803	HPAFII	viability after 31 days	TCGAACTCTCTTCAGCGAAATGG	PYGO1	ENSG00000171016	1.0200933028503614	[478]	[593,491,NaN]	7	hSpCas9	negative selection	10048768
55588812	55588835	15	+	27869803	HPAFII	viability after 31 days	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-1.2904808534556436	[57]	[8,17,NaN]	-7	hSpCas9	negative selection	10048769
55588826	55588849	15	+	28162770	P31FUJ	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.2633905242478015	[142]	[139]	-3	hSpCas9	negative selection	10220543
55546348	55546371	15	-	28162770	P31FUJ	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.623833620414444	[147]	[267]	7	hSpCas9	negative selection	10220544
55548974	55548997	15	-	28162770	P31FUJ	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.5617741129219229	[161]	[280]	6	hSpCas9	negative selection	10220545
55548909	55548932	15	-	28162770	P31FUJ	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-1.2328022044143787	[137]	[68]	-7	hSpCas9	negative selection	10220546
55588812	55588835	15	+	28162770	P31FUJ	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.0730062251097068	[107]	[266]	9	hSpCas9	negative selection	10220547
55548947	55548970	15	-	28162770	P31FUJ	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.8496599557775946	[526]	[1115]	8	hSpCas9	negative selection	10220548
55588790	55588813	15	+	28162770	P31FUJ	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.5454948342579413	[522]	[896]	6	hSpCas9	negative selection	10220549
55548959	55548982	15	-	28162770	P31FUJ	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.7029313997849977	[240]	[460]	7	hSpCas9	negative selection	10220550
55547113	55547136	15	+	28162770	P31FUJ	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.12890579245833864	[185]	[238]	1	hSpCas9	negative selection	10220551
55546503	55546526	15	+	28162770	P31FUJ	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	-0.04015712647198266	[370]	[423]	0	hSpCas9	negative selection	10220552
55588826	55588849	15	+	28162770	TF1	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10389909
55546348	55546371	15	-	28162770	TF1	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10389910
55548974	55548997	15	-	28162770	TF1	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10389911
55548909	55548932	15	-	28162770	TF1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10389912
55588812	55588835	15	+	28162770	TF1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10389913
55548947	55548970	15	-	28162770	TF1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[469]	1	hSpCas9	negative selection	10389914
55588790	55588813	15	+	28162770	TF1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[565]	1	hSpCas9	negative selection	10389915
55548959	55548982	15	-	28162770	TF1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10389916
55547113	55547136	15	+	28162770	TF1	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10389917
55546503	55546526	15	+	28162770	TF1	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10389918
55588826	55588849	15	+	28162770	SKM1	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.5687882550101608	[44]	[117]	5	hSpCas9	negative selection	10559275
55546348	55546371	15	-	28162770	SKM1	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.17799830197799443	[39]	[79]	1	hSpCas9	negative selection	10559276
55548974	55548997	15	-	28162770	SKM1	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.18940306525024392	[62]	[126]	1	hSpCas9	negative selection	10559277
55548909	55548932	15	-	28162770	SKM1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.42968427524324515	[47]	[62]	-4	hSpCas9	negative selection	10559278
55588812	55588835	15	+	28162770	SKM1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.028452575489431975	[44]	[77]	0	hSpCas9	negative selection	10559279
55548947	55548970	15	-	28162770	SKM1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.5624561265020249	[148]	[388]	5	hSpCas9	negative selection	10559280
55588790	55588813	15	+	28162770	SKM1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	-0.09787644962922415	[157]	[260]	-1	hSpCas9	negative selection	10559281
55548959	55548982	15	-	28162770	SKM1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.5963109332896993	[54]	[146]	6	hSpCas9	negative selection	10559282
55547113	55547136	15	+	28162770	SKM1	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.40450683178667435	[49]	[116]	4	hSpCas9	negative selection	10559283
55546503	55546526	15	+	28162770	SKM1	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.6467677851946281	[55]	[154]	6	hSpCas9	negative selection	10559284
55588826	55588849	15	+	28162770	SKM1	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.5687882550101608	[44]	[117]	5	hSpCas9	negative selection	10728641
55546348	55546371	15	-	28162770	SKM1	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.17799830197799443	[39]	[79]	1	hSpCas9	negative selection	10728642
55548974	55548997	15	-	28162770	SKM1	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.18940306525024392	[62]	[126]	1	hSpCas9	negative selection	10728643
55548909	55548932	15	-	28162770	SKM1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.42968427524324515	[47]	[62]	-4	hSpCas9	negative selection	10728644
55588812	55588835	15	+	28162770	SKM1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.028452575489431975	[44]	[77]	0	hSpCas9	negative selection	10728645
55548947	55548970	15	-	28162770	SKM1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.5624561265020249	[148]	[388]	5	hSpCas9	negative selection	10728646
55588790	55588813	15	+	28162770	SKM1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	-0.09787644962922415	[157]	[260]	-1	hSpCas9	negative selection	10728647
55548959	55548982	15	-	28162770	SKM1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.5963109332896993	[54]	[146]	6	hSpCas9	negative selection	10728648
55547113	55547136	15	+	28162770	SKM1	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.40450683178667435	[49]	[116]	4	hSpCas9	negative selection	10728649
55546503	55546526	15	+	28162770	SKM1	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.6467677851946281	[55]	[154]	6	hSpCas9	negative selection	10728650
55588826	55588849	15	+	28162770	PL21	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	1.251123543208125	[138]	[143]	8	hSpCas9	negative selection	10898007
55546348	55546371	15	-	28162770	PL21	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	1.0350803682188237	[110]	[98]	8	hSpCas9	negative selection	10898008
55548974	55548997	15	-	28162770	PL21	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	1.3538490298847732	[168]	[187]	9	hSpCas9	negative selection	10898009
55548909	55548932	15	-	28162770	PL21	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-1.2809870752472963	[133]	[23]	-7	hSpCas9	negative selection	10898010
55588812	55588835	15	+	28162770	PL21	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.0798453807716084	[124]	[114]	8	hSpCas9	negative selection	10898011
55548947	55548970	15	-	28162770	PL21	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.8643288063610517	[495]	[392]	7	hSpCas9	negative selection	10898012
55588790	55588813	15	+	28162770	PL21	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	1.0577308851426241	[382]	[346]	8	hSpCas9	negative selection	10898013
55548959	55548982	15	-	28162770	PL21	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-1.1921778082894403	[146]	[27]	-7	hSpCas9	negative selection	10898014
55547113	55547136	15	+	28162770	PL21	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	1.0074945365469246	[111]	[97]	8	hSpCas9	negative selection	10898015
55546503	55546526	15	+	28162770	PL21	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	1.3772961851627081	[198]	[224]	9	hSpCas9	negative selection	10898016
55588826	55588849	15	+	28162770	P31FUJ	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.2633905242478015	[142]	[139]	-3	hSpCas9	negative selection	11067373
55546348	55546371	15	-	28162770	P31FUJ	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.623833620414444	[147]	[267]	7	hSpCas9	negative selection	11067374
55548974	55548997	15	-	28162770	P31FUJ	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.5617741129219229	[161]	[280]	6	hSpCas9	negative selection	11067375
55548909	55548932	15	-	28162770	P31FUJ	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-1.2328022044143787	[137]	[68]	-7	hSpCas9	negative selection	11067376
55588812	55588835	15	+	28162770	P31FUJ	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.0730062251097068	[107]	[266]	9	hSpCas9	negative selection	11067377
55548947	55548970	15	-	28162770	P31FUJ	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.8496599557775946	[526]	[1115]	8	hSpCas9	negative selection	11067378
55588790	55588813	15	+	28162770	P31FUJ	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.5454948342579413	[522]	[896]	6	hSpCas9	negative selection	11067379
55548959	55548982	15	-	28162770	P31FUJ	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.7029313997849977	[240]	[460]	7	hSpCas9	negative selection	11067380
55547113	55547136	15	+	28162770	P31FUJ	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.12890579245833864	[185]	[238]	1	hSpCas9	negative selection	11067381
55546503	55546526	15	+	28162770	P31FUJ	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	-0.04015712647198266	[370]	[423]	0	hSpCas9	negative selection	11067382
55588826	55588849	15	+	28162770	OCIAML5	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	1.0110516227156159	[57]	[210]	8	hSpCas9	negative selection	11236739
55546348	55546371	15	-	28162770	OCIAML5	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.4840265511223226	[116]	[150]	-3	hSpCas9	negative selection	11236740
55548974	55548997	15	-	28162770	OCIAML5	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.5815866065821937	[153]	[415]	5	hSpCas9	negative selection	11236741
55548909	55548932	15	-	28162770	OCIAML5	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.20353894136537476	[73]	[115]	-1	hSpCas9	negative selection	11236742
55588812	55588835	15	+	28162770	OCIAML5	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	-0.4210167535965222	[111]	[150]	-3	hSpCas9	negative selection	11236743
55548947	55548970	15	-	28162770	OCIAML5	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.9458505266053929	[240]	[837]	7	hSpCas9	negative selection	11236744
55588790	55588813	15	+	28162770	OCIAML5	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.028129158079101435	[319]	[588]	0	hSpCas9	negative selection	11236745
55548959	55548982	15	-	28162770	OCIAML5	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	1.2555324288031573	[112]	[486]	9	hSpCas9	negative selection	11236746
55547113	55547136	15	+	28162770	OCIAML5	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	-0.49417297868876203	[102]	[131]	-3	hSpCas9	negative selection	11236747
55546503	55546526	15	+	28162770	OCIAML5	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.05866609103891579	[149]	[281]	0	hSpCas9	negative selection	11236748
55588826	55588849	15	+	28162770	EOL1	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.04394125568424807	[316]	[161]	0	hSpCas9	negative selection	11406105
55546348	55546371	15	-	28162770	EOL1	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.8613274230766181	[199]	[57]	-6	hSpCas9	negative selection	11406106
55548974	55548997	15	-	28162770	EOL1	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	-0.31108047692260743	[291]	[123]	-2	hSpCas9	negative selection	11406107
55548909	55548932	15	-	28162770	EOL1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.9050075851748893	[222]	[219]	7	hSpCas9	negative selection	11406108
55588812	55588835	15	+	28162770	EOL1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.006290921012071238	[222]	[117]	0	hSpCas9	negative selection	11406109
55548947	55548970	15	-	28162770	EOL1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.5153052939412963	[910]	[685]	4	hSpCas9	negative selection	11406110
55588790	55588813	15	+	28162770	EOL1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.408906331353285	[578]	[404]	4	hSpCas9	negative selection	11406111
55548959	55548982	15	-	28162770	EOL1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-0.7985170057794098	[240]	[72]	-5	hSpCas9	negative selection	11406112
55547113	55547136	15	+	28162770	EOL1	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.21827897462724488	[154]	[94]	2	hSpCas9	negative selection	11406113
55546503	55546526	15	+	28162770	EOL1	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	1.2157790692349804	[303]	[371]	8	hSpCas9	negative selection	11406114
55588826	55588849	15	+	28162770	MOLM13	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.8697514920756894	[164]	[217]	6	hSpCas9	negative selection	11575471
55546348	55546371	15	-	28162770	MOLM13	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.5321106184554213	[237]	[118]	-3	hSpCas9	negative selection	11575472
55548974	55548997	15	-	28162770	MOLM13	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	2.0595777454540487	[213]	[644]	9	hSpCas9	negative selection	11575473
55548909	55548932	15	-	28162770	MOLM13	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.23821979450920505	[264]	[225]	1	hSpCas9	negative selection	11575474
55588812	55588835	15	+	28162770	MOLM13	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.2855593592114858	[218]	[385]	8	hSpCas9	negative selection	11575475
55548947	55548970	15	-	28162770	MOLM13	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.9251455360236596	[723]	[993]	7	hSpCas9	negative selection	11575476
55588790	55588813	15	+	28162770	MOLM13	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	-0.6958090455328461	[577]	[257]	-4	hSpCas9	negative selection	11575477
55548959	55548982	15	-	28162770	MOLM13	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.5418899629883558	[246]	[259]	4	hSpCas9	negative selection	11575478
55547113	55547136	15	+	28162770	MOLM13	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	-0.8476124441833505	[223]	[89]	-5	hSpCas9	negative selection	11575479
55546503	55546526	15	+	28162770	MOLM13	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.6010144647839395	[299]	[328]	4	hSpCas9	negative selection	11575480
55588826	55588849	15	+	28162770	HEL	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.14762301914394185	[210]	[121]	-1	hSpCas9	negative selection	11744837
55546348	55546371	15	-	28162770	HEL	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.25996396664472815	[171]	[91]	-2	hSpCas9	negative selection	11744838
55548974	55548997	15	-	28162770	HEL	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.4510094602396962	[224]	[196]	4	hSpCas9	negative selection	11744839
55548909	55548932	15	-	28162770	HEL	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	1.1291855920804448	[201]	[282]	8	hSpCas9	negative selection	11744840
55588812	55588835	15	+	28162770	HEL	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.6208462261515149	[165]	[326]	9	hSpCas9	negative selection	11744841
55548947	55548970	15	-	28162770	HEL	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.9441381135230458	[636]	[784]	7	hSpCas9	negative selection	11744842
55588790	55588813	15	+	28162770	HEL	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.4687844651230435	[492]	[436]	4	hSpCas9	negative selection	11744843
55548959	55548982	15	-	28162770	HEL	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	-1.2832605865558662	[208]	[54]	-6	hSpCas9	negative selection	11744844
55547113	55547136	15	+	28162770	HEL	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.2596914469659501	[222]	[170]	2	hSpCas9	negative selection	11744845
55546503	55546526	15	+	28162770	HEL	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.12427174306610761	[264]	[184]	1	hSpCas9	negative selection	11744846
55588826	55588849	15	+	28162770	MV411	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.052621373798752424	[94]	[82]	0	hSpCas9	negative selection	11914203
55546348	55546371	15	-	28162770	MV411	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.28733919277016406	[112]	[77]	-2	hSpCas9	negative selection	11914204
55548974	55548997	15	-	28162770	MV411	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.6732702530611134	[232]	[312]	6	hSpCas9	negative selection	11914205
55548909	55548932	15	-	28162770	MV411	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.5139515173226485	[138]	[81]	-4	hSpCas9	negative selection	11914206
55588812	55588835	15	+	28162770	MV411	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.8636509854883712	[136]	[209]	7	hSpCas9	negative selection	11914207
55548947	55548970	15	-	28162770	MV411	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.726865637331574	[481]	[671]	6	hSpCas9	negative selection	11914208
55588790	55588813	15	+	28162770	MV411	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.25700241481830943	[450]	[453]	2	hSpCas9	negative selection	11914209
55548959	55548982	15	-	28162770	MV411	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.46316624183821237	[185]	[215]	4	hSpCas9	negative selection	11914210
55547113	55547136	15	+	28162770	MV411	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.09543445733772538	[129]	[116]	0	hSpCas9	negative selection	11914211
55546503	55546526	15	+	28162770	MV411	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.4246305526891269	[175]	[198]	4	hSpCas9	negative selection	11914212
55588826	55588849	15	+	28162770	MONOMAC1	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	1.892995353802919	[65]	[280]	9	hSpCas9	negative selection	12083569
55546348	55546371	15	-	28162770	MONOMAC1	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	-0.2543700221255052	[76]	[73]	-2	hSpCas9	negative selection	12083570
55548974	55548997	15	-	28162770	MONOMAC1	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	1.1037524807696584	[109]	[270]	8	hSpCas9	negative selection	12083571
55548909	55548932	15	-	28162770	MONOMAC1	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	1.077325564575753	[73]	[178]	8	hSpCas9	negative selection	12083572
55588812	55588835	15	+	28162770	MONOMAC1	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.4415636172636757	[87]	[136]	4	hSpCas9	negative selection	12083573
55548947	55548970	15	-	28162770	MONOMAC1	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.5267908528697622	[352]	[582]	5	hSpCas9	negative selection	12083574
55588790	55588813	15	+	28162770	MONOMAC1	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.1424496192121132	[293]	[371]	1	hSpCas9	negative selection	12083575
55548959	55548982	15	-	28162770	MONOMAC1	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	1.1556347712589166	[129]	[331]	8	hSpCas9	negative selection	12083576
55547113	55547136	15	+	28162770	MONOMAC1	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.22250204445423094	[79]	[106]	2	hSpCas9	negative selection	12083577
55546503	55546526	15	+	28162770	MONOMAC1	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	-0.358787917056166	[131]	[117]	-3	hSpCas9	negative selection	12083578
55588826	55588849	15	+	28162770	OCIAML2	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	-0.5084318579545456	[28]	[112]	-4	hSpCas9	negative selection	12252935
55546348	55546371	15	-	28162770	OCIAML2	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	0.5636400768425849	[25]	[212]	5	hSpCas9	negative selection	12252936
55548974	55548997	15	-	28162770	OCIAML2	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	0.7157832989887201	[28]	[263]	7	hSpCas9	negative selection	12252937
55548909	55548932	15	-	28162770	OCIAML2	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	0.9810661446155308	[16]	[185]	8	hSpCas9	negative selection	12252938
55588812	55588835	15	+	28162770	OCIAML2	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	0.19774868366663229	[27]	[177]	2	hSpCas9	negative selection	12252939
55548947	55548970	15	-	28162770	OCIAML2	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.46144561262461736	[105]	[808]	4	hSpCas9	negative selection	12252940
55588790	55588813	15	+	28162770	OCIAML2	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.48184180467525284	[80]	[626]	5	hSpCas9	negative selection	12252941
55548959	55548982	15	-	28162770	OCIAML2	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	1.109096027112848	[22]	[274]	9	hSpCas9	negative selection	12252942
55547113	55547136	15	+	28162770	OCIAML2	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	0.5187229305583302	[16]	[134]	5	hSpCas9	negative selection	12252943
55546503	55546526	15	+	28162770	OCIAML2	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	0.46427514653595375	[33]	[259]	4	hSpCas9	negative selection	12252944
55588826	55588849	15	+	28162770	OCIAML3	viability	GGGAGCTGGAGAGTTCTCGGCGG	PYGO1	ENSG00000171016	0.6727789003707383	[47]	[230]	6	hSpCas9	negative selection	12422301
55546348	55546371	15	-	28162770	OCIAML3	viability	AATAAGCCACGACAACCAAGAGG	PYGO1	ENSG00000171016	1.2204367065197603	[28]	[203]	8	hSpCas9	negative selection	12422302
55548974	55548997	15	-	28162770	OCIAML3	viability	GGTGGTGATAGTGGACTGGATGG	PYGO1	ENSG00000171016	-0.5298773029044475	[65]	[137]	-4	hSpCas9	negative selection	12422303
55548909	55548932	15	-	28162770	OCIAML3	viability	AAAGCGCAAGGCAAATACACAGG	PYGO1	ENSG00000171016	-0.7866527182665589	[35]	[62]	-5	hSpCas9	negative selection	12422304
55588812	55588835	15	+	28162770	OCIAML3	viability	GAAACTTTGTAAGCGGGAGCTGG	PYGO1	ENSG00000171016	1.0284295658156557	[37]	[233]	8	hSpCas9	negative selection	12422305
55548947	55548970	15	-	28162770	OCIAML3	viability	GGAGGACCAGGTGTACAACTAGG	PYGO1	ENSG00000171016	0.6719870084612454	[141]	[682]	6	hSpCas9	negative selection	12422306
55588790	55588813	15	+	28162770	OCIAML3	viability	AAAGATGAACGTACCATGCGAGG	PYGO1	ENSG00000171016	0.9468996803190575	[132]	[773]	7	hSpCas9	negative selection	12422307
55548959	55548982	15	-	28162770	OCIAML3	viability	CTGGATGGGTTAGGAGGACCAGG	PYGO1	ENSG00000171016	0.09730684156932681	[60]	[196]	0	hSpCas9	negative selection	12422308
55547113	55547136	15	+	28162770	OCIAML3	viability	GGAGCATACTCAGACAATGGAGG	PYGO1	ENSG00000171016	1.5124919809765156	[30]	[266]	9	hSpCas9	negative selection	12422309
55546503	55546526	15	+	28162770	OCIAML3	viability	CAAGTGAGGTGGATGAGCAGAGG	PYGO1	ENSG00000171016	-0.2689122663581178	[90]	[227]	-2	hSpCas9	negative selection	12422310