Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5885
• Symbol: RAD21
• Description: RAD21 cohesin complex component

DataSource: http://genomecrispr.dkfz.de/#!/results/RAD21

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
116857434	116857457	8	-	26472758	Jiyoye	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-5.450805613621699	[57]	[0]	-9	hSpCas9	negative selection	132982
116856697	116856720	8	+	26472758	Jiyoye	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.1643666034529612	[320]	[107]	-7	hSpCas9	negative selection	132983
116854303	116854326	8	-	26472758	Jiyoye	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.7932517083337833	[238]	[51]	-8	hSpCas9	negative selection	132984
116854244	116854267	8	-	26472758	Jiyoye	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-3.9026798810809136	[237]	[11]	-9	hSpCas9	negative selection	132985
116866606	116866629	8	-	26472758	Jiyoye	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.0782514456643684	[13]	[4]	-6	hSpCas9	negative selection	132986
116861835	116861858	8	+	26472758	Jiyoye	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.35513306077479617	[133]	[78]	-3	hSpCas9	negative selection	132987
116856667	116856690	8	-	26472758	Jiyoye	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.4151817038909775	[144]	[81]	-3	hSpCas9	negative selection	132988
116852049	116852072	8	+	26472758	Jiyoye	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.6890399337534296	[185]	[86]	-5	hSpCas9	negative selection	132989
116849011	116849034	8	-	26472758	Jiyoye	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.6511579288104536	[428]	[102]	-8	hSpCas9	negative selection	132990
116857363	116857386	8	+	26472758	Jiyoye	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.163573259995582	[201]	[33]	-8	hSpCas9	negative selection	132991
116857434	116857457	8	-	26472758	KBM7	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.095514365772068	[446,396]	[47,0]	-9	hSpCas9	negative selection	324100
116856697	116856720	8	+	26472758	KBM7	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.142150347996008	[787,866]	[336,372]	-1	hSpCas9	negative selection	324101
116854303	116854326	8	-	26472758	KBM7	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.5691592313135225	[1177,1049]	[235,122]	-8	hSpCas9	negative selection	324102
116854244	116854267	8	-	26472758	KBM7	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-1.2889097307762114	[883,723]	[306,16]	-7	hSpCas9	negative selection	324103
116866606	116866629	8	-	26472758	KBM7	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-2.7056517840884178	[192,127]	[22,0]	-9	hSpCas9	negative selection	324104
116861835	116861858	8	+	26472758	KBM7	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.024365936590440354	[611,430]	[190,279]	0	hSpCas9	negative selection	324105
116856667	116856690	8	-	26472758	KBM7	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.489808201424612	[981,969]	[456,212]	-4	hSpCas9	negative selection	324106
116852049	116852072	8	+	26472758	KBM7	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.4787080274941099	[850,704]	[293,231]	-4	hSpCas9	negative selection	324107
116849011	116849034	8	-	26472758	KBM7	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-0.7461297145301684	[1401,1580]	[550,307]	-6	hSpCas9	negative selection	324108
116857363	116857386	8	+	26472758	KBM7	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.4341066393981725	[794,955]	[191,120]	-7	hSpCas9	negative selection	324109
116857434	116857457	8	-	26472758	Raji	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.2210874053805347	[220]	[21]	-7	hSpCas9	negative selection	515218
116856697	116856720	8	+	26472758	Raji	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.7027538273553315	[518]	[36]	-8	hSpCas9	negative selection	515219
116854303	116854326	8	-	26472758	Raji	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.8856637039846333	[413]	[12]	-9	hSpCas9	negative selection	515220
116854244	116854267	8	-	26472758	Raji	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-0.9594479731046093	[242]	[28]	-6	hSpCas9	negative selection	515221
116866606	116866629	8	-	26472758	Raji	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-2.325575871902507	[107]	[4]	-9	hSpCas9	negative selection	515222
116861835	116861858	8	+	26472758	Raji	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-2.2480971192247896	[347]	[16]	-9	hSpCas9	negative selection	515223
116856667	116856690	8	-	26472758	Raji	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.13995139783003	[218]	[55]	1	hSpCas9	negative selection	515224
116852049	116852072	8	+	26472758	Raji	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.8312159199622572	[367]	[47]	-6	hSpCas9	negative selection	515225
116849011	116849034	8	-	26472758	Raji	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.3976106606441416	[578]	[50]	-7	hSpCas9	negative selection	515226
116857363	116857386	8	+	26472758	Raji	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.1978012956791866	[513]	[25]	-8	hSpCas9	negative selection	515227
116857434	116857457	8	-	26472758	K562	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-8.799975391692005	[527]	[0]	-9	hSpCas9	negative selection	706336
116856697	116856720	8	+	26472758	K562	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.8558087200722073	[595]	[138]	-7	hSpCas9	negative selection	706337
116854303	116854326	8	-	26472758	K562	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-3.417189731085897	[1062]	[83]	-8	hSpCas9	negative selection	706338
116854244	116854267	8	-	26472758	K562	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.4912226855523776	[725]	[108]	-8	hSpCas9	negative selection	706339
116866606	116866629	8	-	26472758	K562	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-3.825970600224951	[167]	[9]	-9	hSpCas9	negative selection	706340
116861835	116861858	8	+	26472758	K562	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.7340481107839119	[531]	[134]	-7	hSpCas9	negative selection	706341
116856667	116856690	8	-	26472758	K562	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.28313874610234513	[771]	[792]	2	hSpCas9	negative selection	706342
116852049	116852072	8	+	26472758	K562	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.44891993409950137	[607]	[375]	-3	hSpCas9	negative selection	706343
116849011	116849034	8	-	26472758	K562	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-2.0811725813115003	[1182]	[235]	-7	hSpCas9	negative selection	706344
116857363	116857386	8	+	26472758	K562	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.127340523172922	[809]	[312]	-6	hSpCas9	negative selection	706345
116847515	116847538	8	-	26627737	DLD1	viability	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.7728769070552574	[1422]	[418,212,161]	-6	hSpCas9	negative selection	837989
116856234	116856257	8	+	26627737	DLD1	viability	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.38098225796420493	[243]	[80,72,136]	4	hSpCas9	negative selection	837990
116847515	116847538	8	-	26627737	GBM cells	viability after 5 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.0108883161427362	[495]	[145,117]	-9	hSpCas9	negative selection	920304
116856234	116856257	8	+	26627737	GBM cells	viability after 5 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.24919516582228773	[130]	[71,94]	4	hSpCas9	negative selection	920305
116847515	116847538	8	-	26627737	GBM cells	viability after 13 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.5446161807480316	[495]	[110,76]	-9	hSpCas9	negative selection	1002619
116856234	116856257	8	+	26627737	GBM cells	viability after 13 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.021254701897258865	[130]	[59,81]	0	hSpCas9	negative selection	1002620
116847515	116847538	8	-	26627737	GBM cells	viability after 21 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-2.7179757514701786	[495]	[41,39]	-9	hSpCas9	negative selection	1084934
116856234	116856257	8	+	26627737	GBM cells	viability after 21 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	-0.07518718992051865	[130]	[77,57]	0	hSpCas9	negative selection	1084935
116847515	116847538	8	-	26627737	RPE1	viability after 9 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	0.49431767948576777	[1720]	[558,1016]	3	hSpCas9	negative selection	1167249
116856234	116856257	8	+	26627737	RPE1	viability after 9 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.9080001236769817	[233]	[119,159]	6	hSpCas9	negative selection	1167250
116847515	116847538	8	-	26627737	RPE1	viability after 12 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	0.3943972516351142	[1720]	[513,706]	2	hSpCas9	negative selection	1249564
116856234	116856257	8	+	26627737	RPE1	viability after 12 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.7305396285796515	[233]	[97,110]	5	hSpCas9	negative selection	1249565
116847515	116847538	8	-	26627737	RPE1	viability after 15 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	0.062481213321014195	[1720]	[486,528]	0	hSpCas9	negative selection	1331879
116856234	116856257	8	+	26627737	RPE1	viability after 15 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.4618843132126944	[233]	[134,227]	7	hSpCas9	negative selection	1331880
116847515	116847538	8	-	26627737	RPE1	viability after 18 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.12301730181876569	[1720]	[425,426]	0	hSpCas9	negative selection	1414194
116856234	116856257	8	+	26627737	RPE1	viability after 18 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.072425174255295	[233]	[126,138]	6	hSpCas9	negative selection	1414195
116847515	116847538	8	-	26627737	HeLa	viability after 8 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.8547552264372377	[1038]	[316,260,190]	-7	hSpCas9	negative selection	1496509
116856234	116856257	8	+	26627737	HeLa	viability after 8 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	2.0369954841282527	[101]	[150,182,203]	9	hSpCas9	negative selection	1496510
116847515	116847538	8	-	26627737	HeLa	viability after 12 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.5224293715027164	[1038]	[188,182,73]	-8	hSpCas9	negative selection	1578824
116856234	116856257	8	+	26627737	HeLa	viability after 12 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.543413704771237	[101]	[111,68,192]	8	hSpCas9	negative selection	1578825
116847515	116847538	8	-	26627737	HeLa	viability after 15 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.5203532756327107	[1038]	[111,168,162]	-8	hSpCas9	negative selection	1661139
116856234	116856257	8	+	26627737	HeLa	viability after 15 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.304781142556498	[101]	[80,148,75]	8	hSpCas9	negative selection	1661140
116847515	116847538	8	-	26627737	HeLa	viability after 18 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.492937222040204	[1038]	[82,136,162]	-8	hSpCas9	negative selection	1743454
116856234	116856257	8	+	26627737	HeLa	viability after 18 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.314515769732569	[101]	[55,122,75]	8	hSpCas9	negative selection	1743455
116847515	116847538	8	-	26627737	HCT116	viability after 6 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.6866598003706333	[1407]	[210,96]	-4	hSpCas9	negative selection	1825769
116856234	116856257	8	+	26627737	HCT116	viability after 6 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	-0.7113940273685172	[448]	[55,35]	-4	hSpCas9	negative selection	1825770
116847515	116847538	8	-	26627737	HCT116	viability after 8 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.08418463263979481	[647]	[391,326,292]	-1	hSpCas9	negative selection	1908084
116856234	116856257	8	+	26627737	HCT116	viability after 8 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.49424710737386074	[159]	[181,100,90]	5	hSpCas9	negative selection	1908085
116847515	116847538	8	-	26627737	HCT116	viability after 9 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-1.3236315799389429	[1407]	[152,147]	-7	hSpCas9	negative selection	1990399
116856234	116856257	8	+	26627737	HCT116	viability after 9 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	-1.248271421663278	[448]	[45,53]	-7	hSpCas9	negative selection	1990400
116847515	116847538	8	-	26627737	HCT116	viability after 12 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.46273583754255465	[647]	[192,244,307]	-5	hSpCas9	negative selection	2072714
116856234	116856257	8	+	26627737	HCT116	viability after 12 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.6072660684174891	[159]	[176,128,73]	5	hSpCas9	negative selection	2072715
116847515	116847538	8	-	26627737	HCT116	viability after 15 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.6034078407593797	[647]	[273,271,192]	-6	hSpCas9	negative selection	2155029
116856234	116856257	8	+	26627737	HCT116	viability after 15 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.7324619051501453	[159]	[213,59,190]	6	hSpCas9	negative selection	2155030
116847515	116847538	8	-	26627737	HCT116	viability after 18 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.19430615535349294	[647]	[351,150,328]	-2	hSpCas9	negative selection	2237344
116856234	116856257	8	+	26627737	HCT116	viability after 18 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.0030472911609039	[159]	[233,131,97]	7	hSpCas9	negative selection	2237345
116858421	116858444	8	+	24336569	HL60	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.4871838385136963	[462]	[698]	-4	hSpCas9	negative selection	2288067
116861829	116861852	8	+	24336569	HL60	viability	GAAGACACATACTCTAAGTCAGG	RAD21	ENSG00000164754	-1.729815307621534	[220]	[140]	-9	hSpCas9	negative selection	2288068
116861835	116861858	8	+	24336569	HL60	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.49732108021428867	[1173]	[1759]	-4	hSpCas9	negative selection	2288069
116861873	116861896	8	+	24336569	HL60	viability	AAATTCTTCAGGTAAAGTAATGG	RAD21	ENSG00000164754	-0.32262871708873186	[418]	[708]	-3	hSpCas9	negative selection	2288070
116861920	116861943	8	-	24336569	HL60	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.9523607770193699	[136]	[560]	7	hSpCas9	negative selection	2288071
116863163	116863186	8	+	24336569	HL60	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.5408957192661934	[351]	[511]	-5	hSpCas9	negative selection	2288072
116863170	116863193	8	+	24336569	HL60	viability	ACAGTCTGCAAGAAGGTATTTGG	RAD21	ENSG00000164754	0.7520049056397252	[742]	[2647]	6	hSpCas9	negative selection	2288073
116866606	116866629	8	-	24336569	HL60	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.4428005800744939	[333]	[259]	-8	hSpCas9	negative selection	2288074
116866618	116866641	8	+	24336569	HL60	viability	CTAAATTACACTCGAACACATGG	RAD21	ENSG00000164754	-0.17079668066697462	[940]	[1768]	-1	hSpCas9	negative selection	2288075
116866625	116866648	8	+	24336569	HL60	viability	ACACTCGAACACATGGGCTTTGG	RAD21	ENSG00000164754	-0.4068924682584834	[618]	[987]	-4	hSpCas9	negative selection	2288076
116858421	116858444	8	+	24336569	KBM7	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	1.0256544479329341	[330]	[1837]	8	hSpCas9	negative selection	2355244
116861829	116861852	8	+	24336569	KBM7	viability	GAAGACACATACTCTAAGTCAGG	RAD21	ENSG00000164754	-1.236648765578737	[342]	[396]	-7	hSpCas9	negative selection	2355245
116861835	116861858	8	+	24336569	KBM7	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.601362296439218	[810]	[728]	-8	hSpCas9	negative selection	2355246
116861873	116861896	8	+	24336569	KBM7	viability	AAATTCTTCAGGTAAAGTAATGG	RAD21	ENSG00000164754	-2.220614045422611	[269]	[157]	-8	hSpCas9	negative selection	2355247
116861920	116861943	8	-	24336569	KBM7	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.10985501275465126	[217]	[550]	-1	hSpCas9	negative selection	2355248
116863163	116863186	8	+	24336569	KBM7	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	1.3487818063910901	[206]	[1437]	9	hSpCas9	negative selection	2355249
116863170	116863193	8	+	24336569	KBM7	viability	ACAGTCTGCAAGAAGGTATTTGG	RAD21	ENSG00000164754	0.9070588396672399	[688]	[3523]	7	hSpCas9	negative selection	2355250
116866606	116866629	8	-	24336569	KBM7	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-2.3309814392350314	[296]	[160]	-8	hSpCas9	negative selection	2355251
116866618	116866641	8	+	24336569	KBM7	viability	CTAAATTACACTCGAACACATGG	RAD21	ENSG00000164754	0.05526468369876847	[740]	[2099]	0	hSpCas9	negative selection	2355252
116866625	116866648	8	+	24336569	KBM7	viability	ACACTCGAACACATGGGCTTTGG	RAD21	ENSG00000164754	-2.601258867801316	[573]	[257]	-9	hSpCas9	negative selection	2355253
116861836	116861859	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.4988223638750294	[2,3]	[3,4]	8	hSpCas9	positive selection	3015443
116863197	116863220	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	0.076041023954531	[1,2]	[1,2]	1	hSpCas9	positive selection	3015444
116866647	116866670	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	0.2655104923726448	[5,5]	[5,6]	5	hSpCas9	positive selection	3015445
116866606	116866629	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-0.738820716714169	[1,2]	[1,0]	-8	hSpCas9	positive selection	3015446
116861836	116861859	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.34555990903680683	[2,2]	[2,0]	-5	hSpCas9	positive selection	3083301
116863197	116863220	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	0.0638262512080251	[1,1]	[1,0]	1	hSpCas9	positive selection	3083302
116866647	116866670	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	-0.23353381710835563	[5,5]	[5,1]	-3	hSpCas9	positive selection	3083303
116866606	116866629	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	0.48197909074602896	[1,1]	[0,2]	7	hSpCas9	positive selection	3083304
116861835	116861858		+	24336571	A375	resistance to PLX after 7 days	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.11165298099109378	[3,6]	[5,5]	4	hSpCas9	positive selection	3139540
116861920	116861943		-	24336571	A375	resistance to PLX after 7 days	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.21356850711490882	[4,5]	[6,5]	6	hSpCas9	positive selection	3139541
116863242	116863265		-	24336571	A375	resistance to PLX after 7 days	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	0.12696729080400748	[7,9]	[9,8]	4	hSpCas9	positive selection	3139542
116863163	116863186		+	24336571	A375	resistance to PLX after 7 days	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.03544758095634426	[6,6]	[5,6]	-1	hSpCas9	positive selection	3139543
116861835	116861858		+	24336571	A375	resistance to PLX after 14 days	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	1.6213502887430744	[4,3]	[4,8]	9	hSpCas9	positive selection	3197333
116861920	116861943		-	24336571	A375	resistance to PLX after 14 days	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.19680518951252668	[5,5]	[2,1]	2	hSpCas9	positive selection	3197334
116863242	116863265		-	24336571	A375	resistance to PLX after 14 days	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	0.14861992784566158	[5,9]	[3,3]	1	hSpCas9	positive selection	3197335
116863163	116863186		+	24336571	A375	resistance to PLX after 14 days	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.10801904442520127	[8,5]	[2,2]	-1	hSpCas9	positive selection	3197336
116861835	116861858		+	24336571	A375	viability after 7 days	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.7139615667536466	[9]	[3,6]	-8	hSpCas9	negative selection	3255126
116861920	116861943		-	24336571	A375	viability after 7 days	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.7567539177701	[10]	[4,5]	-8	hSpCas9	negative selection	3255127
116863242	116863265		-	24336571	A375	viability after 7 days	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	-0.04778774443229966	[9]	[7,9]	0	hSpCas9	negative selection	3255128
116863163	116863186		+	24336571	A375	viability after 7 days	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.7703466965126564	[12]	[6,6]	-8	hSpCas9	negative selection	3255129
116861835	116861858		+	24336571	A375	viability after 14 days	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.868633796972382	[9]	[4,3]	-8	hSpCas9	negative selection	3312919
116861920	116861943		-	24336571	A375	viability after 14 days	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.7260715216942578	[10]	[5,5]	-7	hSpCas9	negative selection	3312920
116863242	116863265		-	24336571	A375	viability after 14 days	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	-0.17951358350880725	[9]	[5,9]	-2	hSpCas9	negative selection	3312921
116863163	116863186		+	24336571	A375	viability after 14 days	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.630847889448346	[12]	[8,5]	-6	hSpCas9	negative selection	3312922
116861835	116861858	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	1.148801754667666	[68,68]	[0,0]	5	hSpCas9	positive selection	3388816
116857434	116857457	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	4.449971289388231	[6,6]	[0,0]	9	hSpCas9	positive selection	3388817
116861920	116861943	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3388818
116861835	116861858	8	+	26780180	HT29	viability (Avana library 4 designs)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	3.13373888549162	[]	[]	8	hSpCas9	negative selection	3453699
116863197	116863220	8	-	26780180	HT29	viability (Avana library 4 designs)	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	6.20671120927337	[]	[]	9	hSpCas9	negative selection	3453700
116866646	116866669	8	+	26780180	HT29	viability (Avana library 4 designs)	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	0.475844550693666	[]	[]	1	hSpCas9	negative selection	3453701
116866606	116866629	8	-	26780180	HT29	viability (Avana library 4 designs)	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	5.49241876134696	[]	[]	9	hSpCas9	negative selection	3453702
116866606	116866629	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-17.3983040822548	[]	[]	-9	hSpCas9	negative selection	3550692
116863197	116863220	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	-15.6871781678772	[]	[]	-9	hSpCas9	negative selection	3550693
116861835	116861858	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-6.42123205857962	[]	[]	-6	hSpCas9	negative selection	3550694
116866646	116866669	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	0.810043058577935	[]	[]	1	hSpCas9	negative selection	3550695
116856663	116856686	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATCCATATCGTCATGTGCAGG	RAD21	ENSG00000164754	-12.4489948397816	[]	[]	-8	hSpCas9	negative selection	3550696
116857363	116857386	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-7.76598051050924	[]	[]	-7	hSpCas9	negative selection	3550697
116866606	116866629	8	-	26780180	A375	viability (Avana lentiGuide)	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	23.9162322197642	[]	[]	9	hSpCas9	negative selection	3659351
116863197	116863220	8	-	26780180	A375	viability (Avana lentiGuide)	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	29.3822525543063	[]	[]	9	hSpCas9	negative selection	3659352
116861835	116861858	8	+	26780180	A375	viability (Avana lentiGuide)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	19.5920128177438	[]	[]	8	hSpCas9	negative selection	3659353
116866646	116866669	8	+	26780180	A375	viability (Avana lentiGuide)	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	-1.41721202278307	[]	[]	-2	hSpCas9	negative selection	3659354
116856663	116856686	8	+	26780180	A375	viability (Avana lentiGuide)	TCATCCATATCGTCATGTGCAGG	RAD21	ENSG00000164754	8.44284383746855	[]	[]	6	hSpCas9	negative selection	3659355
116857363	116857386	8	+	26780180	A375	viability (Avana lentiGuide)	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	9.1686623904237	[]	[]	6	hSpCas9	negative selection	3659356
116866606	116866629	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.5301812097730205	[5]	[0,1]	-9	hSpCas9	positive selection	3767958
116863197	116863220	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	-1.707321197046757	[5]	[0,0]	-9	hSpCas9	positive selection	3767959
116861835	116861858	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9533043166181975	[4]	[1,2]	-8	hSpCas9	positive selection	3767960
116866646	116866669	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	0.06988212342353423	[6]	[6,6]	1	hSpCas9	positive selection	3767961
116856663	116856686	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATCCATATCGTCATGTGCAGG	RAD21	ENSG00000164754	-0.6503383873884656	[5]	[2,2]	-7	hSpCas9	positive selection	3767962
116857363	116857386	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.6258003480176152	[7]	[3,4]	-7	hSpCas9	positive selection	3767963
116866606	116866629	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-0.7695478348787546	[4]	[1,2]	-7	hSpCas9	positive selection	3876565
116863197	116863220	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTAGTTCGAATCTATCACAGG	RAD21	ENSG00000164754	-2.5237618464695313	[5]	[0,0]	-9	hSpCas9	positive selection	3876566
116861835	116861858	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.4909565081780427	[5]	[3,2]	-6	hSpCas9	positive selection	3876567
116866646	116866669	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTAGCTTCTTATCCCAATGGG	RAD21	ENSG00000164754	0.17793927125658676	[7]	[7,6]	4	hSpCas9	positive selection	3876568
116856663	116856686	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATCCATATCGTCATGTGCAGG	RAD21	ENSG00000164754	-0.4307582201978404	[6]	[2,4]	-5	hSpCas9	positive selection	3876569
116857363	116857386	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.30087740086940357	[6]	[4,4]	-4	hSpCas9	positive selection	3876570
116861835	116861858	8	+	26780180	A375	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.815657944280961	[]	[]	3	hSpCas9	negative selection	3986973
116861920	116861943	8	-	26780180	A375	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.803077838109528	[]	[]	3	hSpCas9	negative selection	3986974
116858412	116858435	8	-	26780180	A375	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	0.744259485295113	[]	[]	2	hSpCas9	negative selection	3986975
116863163	116863186	8	+	26780180	A375	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	1.20663276772021	[]	[]	6	hSpCas9	negative selection	3986976
116857434	116857457	8	-	26780180	A375	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	0.991862202429399	[]	[]	4	hSpCas9	negative selection	3986977
116858421	116858444	8	+	26780180	A375	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	1.53609777351287	[]	[]	8	hSpCas9	negative selection	3986978
116861835	116861858	8	+	26780180	HT29	viability (GeCKOv2 library)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	2.03492024132572	[]	[]	9	hSpCas9	negative selection	4094939
116861920	116861943	8	-	26780180	HT29	viability (GeCKOv2 library)	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	1.27645218554949	[]	[]	6	hSpCas9	negative selection	4094940
116858412	116858435	8	-	26780180	HT29	viability (GeCKOv2 library)	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	1.19505190285756	[]	[]	6	hSpCas9	negative selection	4094941
116863163	116863186	8	+	26780180	HT29	viability (GeCKOv2 library)	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	2.11447080468196	[]	[]	9	hSpCas9	negative selection	4094942
116857434	116857457	8	-	26780180	HT29	viability (GeCKOv2 library)	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	1.48512626693726	[]	[]	7	hSpCas9	negative selection	4094943
116858421	116858444	8	+	26780180	HT29	viability (GeCKOv2 library)	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.215511283079207	[]	[]	0	hSpCas9	negative selection	4094944
116861835	116861858	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.09852112965249402	[3]	[1,2]	2	hSpCas9	positive selection	4164886
116861920	116861943	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.47131501184806457	[3]	[1,1]	-8	hSpCas9	positive selection	4164887
116863242	116863265	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	0.06263685358811127	[3]	[2,1]	1	hSpCas9	positive selection	4164888
116863163	116863186	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.5874551417875162	[3]	[1,1]	-9	hSpCas9	positive selection	4164889
116861835	116861858	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.5617874343564302	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4228908
116861920	116861943	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.8762729362384046	[1]	[0,3,1,0]	6	hSpCas9	positive selection	4228909
116863242	116863265	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATAGGTGAAAATGGCATTACGG	RAD21	ENSG00000164754	-0.49344101887106995	[3]	[0,2,0,0]	-7	hSpCas9	positive selection	4228910
116863163	116863186	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.016780796289369453	[3]	[0,4,1,0]	0	hSpCas9	positive selection	4228911
116858421	116858444	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.17317481460087727	[3]	[3,2]	3	hSpCas9	positive selection	4293694
116858412	116858435	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.7356010799142464	[1]	[0,0]	-9	hSpCas9	positive selection	4293695
116863163	116863186	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.2528355840529525	[2]	[3,0]	-5	hSpCas9	positive selection	4293696
116861835	116861858	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.19126016045030445	[3]	[2,1]	-4	hSpCas9	positive selection	4357952
116857434	116857457	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.8026179045889107	[1]	[0,0]	-9	hSpCas9	positive selection	4357953
116861920	116861943	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.728632524855117	[1]	[0,0]	-9	hSpCas9	positive selection	4357954
116861836	116861858	8	+	27760321	OCIAML3	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.0950301510050013	[418,369]	[141,146]	-7	hSpCas9	negative selection	4432856
116866606	116866628	8	-	27760321	OCIAML3	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.9554729802781414	[361,305]	[80,48]	-9	hSpCas9	negative selection	4432857
116856250	116856272	8	+	27760321	OCIAML3	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.5105813626998744	[663,469]	[257,372]	-5	hSpCas9	negative selection	4432858
116857364	116857386	8	+	27760321	OCIAML3	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.6501221784823787	[172,178]	[55,129]	-6	hSpCas9	negative selection	4432859
116858412	116858434	8	-	27760321	OCIAML3	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.253990951063702	[142,117]	[62,15]	-8	hSpCas9	negative selection	4432860
116861836	116861858	8	+	27760321	OCIAML2	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.37850088319635533	[418,369]	[175,335]	-4	hSpCas9	negative selection	4516319
116866606	116866628	8	-	27760321	OCIAML2	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-2.504875513001492	[361,305]	[46,47]	-9	hSpCas9	negative selection	4516320
116856250	116856272	8	+	27760321	OCIAML2	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.47620823933441964	[663,469]	[361,278]	-5	hSpCas9	negative selection	4516321
116857364	116857386	8	+	27760321	OCIAML2	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.9388609123002893	[172,178]	[46,110]	-7	hSpCas9	negative selection	4516322
116858412	116858434	8	-	27760321	OCIAML2	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	0.09864331913980506	[142,117]	[77,157]	1	hSpCas9	negative selection	4516323
116861836	116861858	8	+	27760321	MV411	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.3305375026608421	[418,369]	[12,238]	-7	hSpCas9	negative selection	4599782
116866606	116866628	8	-	27760321	MV411	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.8391739362278254	[361,305]	[34,100]	-8	hSpCas9	negative selection	4599783
116856250	116856272	8	+	27760321	MV411	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	0.4104775936119697	[663,469]	[684,201]	3	hSpCas9	negative selection	4599784
116857364	116857386	8	+	27760321	MV411	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.7717310725347157	[172,178]	[0,83]	-8	hSpCas9	negative selection	4599785
116858412	116858434	8	-	27760321	MV411	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.1596442171489043	[142,117]	[1,44]	-8	hSpCas9	negative selection	4599786
116861836	116861858	8	+	27760321	HL60	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.2745344976052442	[418,369]	[164,98]	-8	hSpCas9	negative selection	4683245
116866606	116866628	8	-	27760321	HL60	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.205384016154776	[361,305]	[2,11]	-9	hSpCas9	negative selection	4683246
116856250	116856272	8	+	27760321	HL60	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.11105863903715885	[663,469]	[398,450]	-1	hSpCas9	negative selection	4683247
116857364	116857386	8	+	27760321	HL60	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.2464991759408948	[172,178]	[44,14]	-9	hSpCas9	negative selection	4683248
116858412	116858434	8	-	27760321	HL60	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-3.094096325198118	[142,117]	[9,14]	-9	hSpCas9	negative selection	4683249
116861836	116861858	8	+	27760321	HT1080	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-3.9803123056903136	[369,288]	[14,0]	-8	hSpCas9	negative selection	4766708
116866606	116866628	8	-	27760321	HT1080	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-6.762361955484028	[305,238]	[0,0]	-9	hSpCas9	negative selection	4766709
116856250	116856272	8	+	27760321	HT1080	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.4738341485037745	[469,366]	[99,141]	-2	hSpCas9	negative selection	4766710
116857364	116857386	8	+	27760321	HT1080	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-5.989785225073555	[178,139]	[0,0]	-9	hSpCas9	negative selection	4766711
116858412	116858434	8	-	27760321	HT1080	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	3.3760136053344634	[117,91]	[491,370]	9	hSpCas9	negative selection	4766712
116861836	116861858	8	+	27760321	HT29	viability after 7 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.10892173614005557	[369,288]	[447,285,449]	-2	hSpCas9	negative selection	4850171
116866606	116866628	8	-	27760321	HT29	viability after 7 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-2.6633412187074845	[305,238]	[44,83,35]	-9	hSpCas9	negative selection	4850172
116856250	116856272	8	+	27760321	HT29	viability after 7 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.18296389692532114	[469,366]	[557,455,420]	-3	hSpCas9	negative selection	4850173
116857364	116857386	8	+	27760321	HT29	viability after 7 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.923228337954009	[178,139]	[11,116,27]	-9	hSpCas9	negative selection	4850174
116858412	116858434	8	-	27760321	HT29	viability after 7 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.8122959565911347	[117,91]	[12,71,26]	-9	hSpCas9	negative selection	4850175
116861836	116861858	8	+	27760321	HT29	viability after 25 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.7119953769020408	[369,288]	[122,291,286]	-5	hSpCas9	negative selection	4933634
116866606	116866628	8	-	27760321	HT29	viability after 25 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-3.3336766104935096	[305,238]	[0,66,25]	-8	hSpCas9	negative selection	4933635
116856250	116856272	8	+	27760321	HT29	viability after 25 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.9730921777808402	[469,366]	[95,355,292]	-6	hSpCas9	negative selection	4933636
116857364	116857386	8	+	27760321	HT29	viability after 25 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.6312234242409283	[178,139]	[44,224,83]	-5	hSpCas9	negative selection	4933637
116858412	116858434	8	-	27760321	HT29	viability after 25 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.5456216562216476	[117,91]	[49,2,72]	-7	hSpCas9	negative selection	4933638
116861836	116861858	8	+	27760321	HT29	viability after 22 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.23588516657802913	[369,288]	[364,311,291]	-2	hSpCas9	negative selection	5017097
116866606	116866628	8	-	27760321	HT29	viability after 22 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.192378208008554	[305,238]	[0,21,2]	-9	hSpCas9	negative selection	5017098
116856250	116856272	8	+	27760321	HT29	viability after 22 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.650195474507357	[469,366]	[294,343,285]	-5	hSpCas9	negative selection	5017099
116857364	116857386	8	+	27760321	HT29	viability after 22 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.4114896918466735	[178,139]	[65,203,147]	-4	hSpCas9	negative selection	5017100
116858412	116858434	8	-	27760321	HT29	viability after 22 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.6706058054043513	[117,91]	[0,3,52]	-8	hSpCas9	negative selection	5017101
116861836	116861858	8	+	27760321	HT29	viability after 19 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.17726705531755638	[369,288]	[304,656,307]	1	hSpCas9	negative selection	5100560
116866606	116866628	8	-	27760321	HT29	viability after 19 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-6.035886182034273	[305,238]	[0,11,0]	-9	hSpCas9	negative selection	5100561
116856250	116856272	8	+	27760321	HT29	viability after 19 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.9123773241047303	[469,366]	[253,261,246]	-6	hSpCas9	negative selection	5100562
116857364	116857386	8	+	27760321	HT29	viability after 19 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.489959912686672	[178,139]	[79,40,74]	-7	hSpCas9	negative selection	5100563
116858412	116858434	8	-	27760321	HT29	viability after 19 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.6355361673062745	[117,91]	[4,84,22]	-7	hSpCas9	negative selection	5100564
116861836	116861858	8	+	27760321	HT29	viability after 16 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.331828665852693	[369,288]	[392,336,156]	-4	hSpCas9	negative selection	5184023
116866606	116866628	8	-	27760321	HT29	viability after 16 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.233517885769118	[305,238]	[6,15,0]	-9	hSpCas9	negative selection	5184024
116856250	116856272	8	+	27760321	HT29	viability after 16 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.7831881607897356	[469,366]	[186,354,263]	-6	hSpCas9	negative selection	5184025
116857364	116857386	8	+	27760321	HT29	viability after 16 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.22934104157569402	[178,139]	[140,214,97]	-3	hSpCas9	negative selection	5184026
116858412	116858434	8	-	27760321	HT29	viability after 16 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.1410753577205925	[117,91]	[64,7,10]	-8	hSpCas9	negative selection	5184027
116861836	116861858	8	+	27760321	HT29	viability after 13 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.1447105650845795	[369,288]	[360,359,317]	-2	hSpCas9	negative selection	5267486
116866606	116866628	8	-	27760321	HT29	viability after 13 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.997733247267361	[305,238]	[5,1,20]	-9	hSpCas9	negative selection	5267487
116856250	116856272	8	+	27760321	HT29	viability after 13 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.6215595037711965	[469,366]	[336,402,212]	-6	hSpCas9	negative selection	5267488
116857364	116857386	8	+	27760321	HT29	viability after 13 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.7323687991314378	[178,139]	[27,63,73]	-8	hSpCas9	negative selection	5267489
116858412	116858434	8	-	27760321	HT29	viability after 13 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.4717403488328753	[117,91]	[39,0,87]	-8	hSpCas9	negative selection	5267490
116861836	116861858	8	+	27760321	HT29	viability after 10 days	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.031895861251317936	[369,288]	[345,603,265]	0	hSpCas9	negative selection	5350949
116866606	116866628	8	-	27760321	HT29	viability after 10 days	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.585883539359902	[305,238]	[18,21,1]	-9	hSpCas9	negative selection	5350950
116856250	116856272	8	+	27760321	HT29	viability after 10 days	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-0.013723980079695774	[469,366]	[372,748,438]	0	hSpCas9	negative selection	5350951
116857364	116857386	8	+	27760321	HT29	viability after 10 days	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.01290249152704459	[178,139]	[181,160,246]	0	hSpCas9	negative selection	5350952
116858412	116858434	8	-	27760321	HT29	viability after 10 days	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.6619913407987588	[117,91]	[36,17,67]	-8	hSpCas9	negative selection	5350953
116861836	116861858	8	+	27760321	MOLM13	viability	CATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.36430399683001546	[418,369]	[43,491]	2	hSpCas9	negative selection	5434412
116866606	116866628	8	-	27760321	MOLM13	viability	TGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-1.0162920324807223	[361,305]	[0,170]	-6	hSpCas9	negative selection	5434413
116856250	116856272	8	+	27760321	MOLM13	viability	CAACGGGATCCACTGAATCAGG	RAD21	ENSG00000164754	-1.4290999086240428	[663,469]	[49,174]	-7	hSpCas9	negative selection	5434414
116857364	116857386	8	+	27760321	MOLM13	viability	CTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	0.10443742808392198	[172,178]	[197,29]	0	hSpCas9	negative selection	5434415
116858412	116858434	8	-	27760321	MOLM13	viability	AGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-4.805717598894599	[142,117]	[0,3]	-9	hSpCas9	negative selection	5434416
116874375	116874398	8	+	27661255	K562	viability	GATGCGGGCCCAAGCTGCATGGG	RAD21	ENSG00000164754	-0.525425928212006	[1199,1497]	[810,689]	-7	dCas9-KRAB	negative selection	5505958
116874381	116874404	8	+	27661255	K562	viability	GGCCCAAGCTGCATGGGTCCGGG	RAD21	ENSG00000164754	0.2736472138600522	[876,742]	[858,720]	8	dCas9-KRAB	negative selection	5505959
116874206	116874229	8	-	27661255	K562	viability	GGACCGGGCCGCCTACTCCGCGG	RAD21	ENSG00000164754	-0.2931032544184594	[1249,1308]	[948,734]	-7	dCas9-KRAB	negative selection	5505960
116858421	116858444	8	+	27260156	BXPC3	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.2008994055426177	[654]	[559,420,766,655]	-4	hSpCas9	negative selection	5566154
116858412	116858435	8	-	27260156	BXPC3	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.683420021137401	[79]	[18,22,29,33]	-9	hSpCas9	negative selection	5566155
116863163	116863186	8	+	27260156	BXPC3	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.6177509435862449	[305]	[193,228,124,293]	-8	hSpCas9	negative selection	5566156
116861835	116861858	8	+	27260156	BXPC3	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.7034678006948425	[564]	[387,345,394,311]	-8	hSpCas9	negative selection	5630412
116857434	116857457	8	-	27260156	BXPC3	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.8230116395513285	[92]	[7,14,22,8]	-9	hSpCas9	negative selection	5630413
116861920	116861943	8	-	27260156	BXPC3	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.11861983653122077	[124]	[130,76,182,186]	2	hSpCas9	negative selection	5630414
116858421	116858444	8	+	27260156	A673	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.23065848846035047	[654]	[745,743,539,656]	-5	hSpCas9	negative selection	5687405
116858412	116858435	8	-	27260156	A673	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.9806238304919601	[79]	[78,36,41,39]	-9	hSpCas9	negative selection	5687406
116863163	116863186	8	+	27260156	A673	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.5033410744784985	[305]	[248,203,308,274]	-8	hSpCas9	negative selection	5687407
116861835	116861858	8	+	27260156	A673	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9174267204741849	[564]	[418,332,315,376]	-9	hSpCas9	negative selection	5751663
116857434	116857457	8	-	27260156	A673	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.7009549711666394	[92]	[57,62,118,30]	-9	hSpCas9	negative selection	5751664
116861920	116861943	8	-	27260156	A673	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.32038362537822174	[124]	[175,105,80,124]	-7	hSpCas9	negative selection	5751665
116858421	116858444	8	+	27260156	A375	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.4508703976686324	[654]	[529,719,608,416]	-6	hSpCas9	negative selection	5808656
116858412	116858435	8	-	27260156	A375	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.070347702326722	[79]	[0,98,0,0]	-9	hSpCas9	negative selection	5808657
116863163	116863186	8	+	27260156	A375	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.5664101108605777	[305]	[159,114,106,101]	-9	hSpCas9	negative selection	5808658
116861835	116861858	8	+	27260156	A375	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.1494268753259558	[564]	[221,217,677,84]	-8	hSpCas9	negative selection	5872914
116857434	116857457	8	-	27260156	A375	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.8236831792907173	[92]	[15,0,23,17]	-9	hSpCas9	negative selection	5872915
116861920	116861943	8	-	27260156	A375	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.8206580747940024	[124]	[148,24,104,47]	-8	hSpCas9	negative selection	5872916
116858421	116858444	8	+	27260156	COLO741	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.1699049975542098	[654]	[773,636,815]	-4	hSpCas9	negative selection	5929907
116858412	116858435	8	-	27260156	COLO741	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.5334558434021544	[79]	[17,3,29]	-9	hSpCas9	negative selection	5929908
116863163	116863186	8	+	27260156	COLO741	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.846995734879513	[305]	[281,241,138]	-9	hSpCas9	negative selection	5929909
116861835	116861858	8	+	27260156	COLO741	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.8674356464521296	[564]	[586,274,343]	-9	hSpCas9	negative selection	5994165
116857434	116857457	8	-	27260156	COLO741	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.312029471950321	[92]	[3,10,2]	-9	hSpCas9	negative selection	5994166
116861920	116861943	8	-	27260156	COLO741	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.1350738076080269	[124]	[64,322,131]	3	hSpCas9	negative selection	5994167
116858421	116858444	8	+	27260156	CAL120	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.3051223333672374	[654]	[748,624,618]	-4	hSpCas9	negative selection	6051158
116858412	116858435	8	-	27260156	CAL120	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.5514172424403654	[79]	[6,0,40]	-9	hSpCas9	negative selection	6051159
116863163	116863186	8	+	27260156	CAL120	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.0586727546960117	[305]	[92,212,227]	-8	hSpCas9	negative selection	6051160
116861835	116861858	8	+	27260156	CAL120	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-2.217757867882494	[564]	[185,142,129]	-9	hSpCas9	negative selection	6115416
116857434	116857457	8	-	27260156	CAL120	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-5.381751808382246	[92]	[0,0,5]	-9	hSpCas9	negative selection	6115417
116861920	116861943	8	-	27260156	CAL120	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-1.6788812182999866	[124]	[41,68,33]	-9	hSpCas9	negative selection	6115418
116858421	116858444	8	+	27260156	CADOES1	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.15669395413644843	[654]	[539,440,523,685]	-3	hSpCas9	negative selection	6172409
116858412	116858435	8	-	27260156	CADOES1	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.159050318917809	[79]	[11,15,12,25]	-9	hSpCas9	negative selection	6172410
116863163	116863186	8	+	27260156	CADOES1	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.2193600725162115	[305]	[143,121,96,125]	-9	hSpCas9	negative selection	6172411
116861835	116861858	8	+	27260156	CADOES1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.8073577788956238	[564]	[332,260,304,301]	-8	hSpCas9	negative selection	6236667
116857434	116857457	8	-	27260156	CADOES1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.3787015222976913	[92]	[32,30,36,31]	-9	hSpCas9	negative selection	6236668
116861920	116861943	8	-	27260156	CADOES1	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.6555147774634063	[124]	[45,76,105,65]	-8	hSpCas9	negative selection	6236669
116858421	116858444	8	+	27260156	EWS502	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.11024019444581157	[654]	[876,649,645,810]	2	hSpCas9	negative selection	6293660
116858412	116858435	8	-	27260156	EWS502	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.2403520632276397	[79]	[26,15,17,8]	-9	hSpCas9	negative selection	6293661
116863163	116863186	8	+	27260156	EWS502	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.082031273103851	[305]	[110,96,189,226]	-9	hSpCas9	negative selection	6293662
116861835	116861858	8	+	27260156	EWS502	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.1158424547742067	[564]	[327,198,290,282]	-9	hSpCas9	negative selection	6357918
116857434	116857457	8	-	27260156	EWS502	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.446108388057459	[92]	[0,13,11,9]	-9	hSpCas9	negative selection	6357919
116861920	116861943	8	-	27260156	EWS502	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.6899119629648642	[124]	[89,98,85,48]	-8	hSpCas9	negative selection	6357920
116858421	116858444	8	+	27260156	EW8	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.0936435140388297	[654]	[580,531,437,456]	-2	hSpCas9	negative selection	6414911
116858412	116858435	8	-	27260156	EW8	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.5902809163151757	[79]	[15,17,35,12]	-9	hSpCas9	negative selection	6414912
116863163	116863186	8	+	27260156	EW8	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.1199876652865686	[305]	[126,152,106,71]	-9	hSpCas9	negative selection	6414913
116861835	116861858	8	+	27260156	EW8	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.2566001019725952	[564]	[210,197,150,214]	-9	hSpCas9	negative selection	6479169
116857434	116857457	8	-	27260156	EW8	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.464218315859016	[92]	[23,8,11,10]	-9	hSpCas9	negative selection	6479170
116861920	116861943	8	-	27260156	EW8	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.7473949025542996	[124]	[91,60,28,67]	-8	hSpCas9	negative selection	6479171
116858421	116858444	8	+	27260156	CORL105	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.3507396556399035	[654]	[644,487,735,560]	-6	hSpCas9	negative selection	6536162
116858412	116858435	8	-	27260156	CORL105	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.3535636687210428	[79]	[69,41,12,18]	-9	hSpCas9	negative selection	6536163
116863163	116863186	8	+	27260156	CORL105	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.1341884081249554	[305]	[70,306,156,110]	-9	hSpCas9	negative selection	6536164
116861835	116861858	8	+	27260156	CORL105	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9732685329987857	[564]	[282,462,358,241]	-9	hSpCas9	negative selection	6600420
116857434	116857457	8	-	27260156	CORL105	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.2398634965610924	[92]	[17,16,9,44]	-9	hSpCas9	negative selection	6600421
116861920	116861943	8	-	27260156	CORL105	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.14676940343846523	[124]	[166,122,225,142]	2	hSpCas9	negative selection	6600422
116858421	116858444	8	+	27260156	HS294T	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.49268702365303196	[654]	[227,268,499,459]	6	hSpCas9	negative selection	6657413
116858412	116858435	8	-	27260156	HS294T	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.4291185259122878	[79]	[2,15,8,19]	-9	hSpCas9	negative selection	6657414
116863163	116863186	8	+	27260156	HS294T	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.7680293628310593	[305]	[53,57,60,113]	-8	hSpCas9	negative selection	6657415
116861835	116861858	8	+	27260156	HS294T	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.6037505635722771	[564]	[54,77,310,140]	-7	hSpCas9	negative selection	6721671
116857434	116857457	8	-	27260156	HS294T	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.639265959833235	[92]	[1,4,7,8]	-9	hSpCas9	negative selection	6721672
116861920	116861943	8	-	27260156	HS294T	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.06765678269593045	[124]	[53,41,49,35]	-1	hSpCas9	negative selection	6721673
116858421	116858444	8	+	27260156	HCC44	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.062135490799141935	[654]	[922,537,931,768]	1	hSpCas9	negative selection	6778664
116858412	116858435	8	-	27260156	HCC44	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-3.580623955967651	[79]	[13,9,3,1]	-9	hSpCas9	negative selection	6778665
116863163	116863186	8	+	27260156	HCC44	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.6539741481960164	[305]	[223,155,348,181]	-7	hSpCas9	negative selection	6778666
116861835	116861858	8	+	27260156	HCC44	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.7301948486677827	[564]	[227,237,245,66]	-9	hSpCas9	negative selection	6842922
116857434	116857457	8	-	27260156	HCC44	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.7281510922778063	[92]	[3,9,12,4]	-9	hSpCas9	negative selection	6842923
116861920	116861943	8	-	27260156	HCC44	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-1.4744614383765233	[124]	[47,63,28,55]	-9	hSpCas9	negative selection	6842924
116858421	116858444	8	+	27260156	G402	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.00785344846780106	[654]	[800,740,1001,637]	0	hSpCas9	negative selection	6899915
116858412	116858435	8	-	27260156	G402	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.5188838779903602	[79]	[0,95,4,32]	-9	hSpCas9	negative selection	6899916
116863163	116863186	8	+	27260156	G402	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.8171776646062097	[305]	[204,234,233,174]	-7	hSpCas9	negative selection	6899917
116861835	116861858	8	+	27260156	G402	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9933401656103441	[564]	[384,366,108,520]	-8	hSpCas9	negative selection	6964173
116857434	116857457	8	-	27260156	G402	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.451312900441674	[92]	[4,58,0,17]	-9	hSpCas9	negative selection	6964174
116861920	116861943	8	-	27260156	G402	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.35962260724885775	[124]	[175,169,121,22]	-4	hSpCas9	negative selection	6964175
116858421	116858444	8	+	27260156	L33	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.3719213271394791	[654]	[856,336,547,838]	7	hSpCas9	negative selection	7021166
116858412	116858435	8	-	27260156	L33	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.277286487988876	[79]	[33,3,9,5]	-9	hSpCas9	negative selection	7021167
116863163	116863186	8	+	27260156	L33	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.22657048719916972	[305]	[252,81,164,329]	-5	hSpCas9	negative selection	7021168
116861835	116861858	8	+	27260156	L33	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.42595327962043794	[564]	[486,109,230,555]	-7	hSpCas9	negative selection	7085424
116857434	116857457	8	-	27260156	L33	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.6218279859794036	[92]	[19,10,5,3]	-9	hSpCas9	negative selection	7085425
116861920	116861943	8	-	27260156	L33	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.14577926743364644	[124]	[129,60,58,78]	-3	hSpCas9	negative selection	7085426
116858421	116858444	8	+	27260156	K562	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.16335484615607715	[654]	[503,481,501,575]	-2	hSpCas9	negative selection	7142417
116858412	116858435	8	-	27260156	K562	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-3.802595019871937	[79]	[0,14,3,0]	-9	hSpCas9	negative selection	7142418
116863163	116863186	8	+	27260156	K562	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.012210254627170958	[305]	[166,143,565,192]	0	hSpCas9	negative selection	7142419
116861835	116861858	8	+	27260156	K562	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-2.4824161746055573	[564]	[201,70,34,61]	-9	hSpCas9	negative selection	7206675
116857434	116857457	8	-	27260156	K562	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.2316299273852187	[92]	[1,22,254,0]	-3	hSpCas9	negative selection	7206676
116861920	116861943	8	-	27260156	K562	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-1.5926510776102818	[124]	[34,13,53,41]	-9	hSpCas9	negative selection	7206677
116858421	116858444	8	+	27260156	HT29	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.1502229720135722	[654]	[698,971,665,566]	-3	hSpCas9	negative selection	7263668
116858412	116858435	8	-	27260156	HT29	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.0572764133177968	[79]	[16,43,22,11]	-9	hSpCas9	negative selection	7263669
116863163	116863186	8	+	27260156	HT29	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.9855082890347022	[305]	[184,286,139,150]	-8	hSpCas9	negative selection	7263670
116861835	116861858	8	+	27260156	HT29	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.1180193358378228	[564]	[293,292,349,321]	-9	hSpCas9	negative selection	7327926
116857434	116857457	8	-	27260156	HT29	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.4063040767762516	[92]	[6,31,15,28]	-9	hSpCas9	negative selection	7327927
116861920	116861943	8	-	27260156	HT29	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.16413395108933182	[124]	[185,124,120,114]	-3	hSpCas9	negative selection	7327928
116858421	116858444	8	+	27260156	MHHES1	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.04620347754138587	[654]	[718,1163,784,466]	0	hSpCas9	negative selection	7384919
116858412	116858435	8	-	27260156	MHHES1	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.5207594120446464	[79]	[104,81,44,31]	-7	hSpCas9	negative selection	7384920
116863163	116863186	8	+	27260156	MHHES1	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.3607461542467715	[305]	[556,198,211,153]	-6	hSpCas9	negative selection	7384921
116861835	116861858	8	+	27260156	MHHES1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.8260731872535572	[564]	[559,433,298,202]	-9	hSpCas9	negative selection	7449177
116857434	116857457	8	-	27260156	MHHES1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.4752407912277814	[92]	[18,73,34,25]	-9	hSpCas9	negative selection	7449178
116861920	116861943	8	-	27260156	MHHES1	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.1774769679886372	[124]	[235,207,90,120]	3	hSpCas9	negative selection	7449179
116858421	116858444	8	+	27260156	MEWO	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.041755276044045164	[654]	[521,717,530]	-1	hSpCas9	negative selection	7506170
116858412	116858435	8	-	27260156	MEWO	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.4374525942783296	[79]	[2,52,21]	-9	hSpCas9	negative selection	7506171
116863163	116863186	8	+	27260156	MEWO	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.3605747501205995	[305]	[270,257,148]	-7	hSpCas9	negative selection	7506172
116861835	116861858	8	+	27260156	MEWO	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.7461131699458412	[564]	[323,334,287]	-9	hSpCas9	negative selection	7570428
116857434	116857457	8	-	27260156	MEWO	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.276466087659765	[92]	[18,32,1]	-9	hSpCas9	negative selection	7570429
116861920	116861943	8	-	27260156	MEWO	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.43270840126017207	[124]	[101,61,98]	-7	hSpCas9	negative selection	7570430
116858421	116858444	8	+	27260156	LNCAPCLONEFGC	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.06273282291077475	[654]	[507,545,617,609]	-1	hSpCas9	negative selection	7627421
116858412	116858435	8	-	27260156	LNCAPCLONEFGC	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.9787075693978773	[79]	[25,24,11,8]	-9	hSpCas9	negative selection	7627422
116863163	116863186	8	+	27260156	LNCAPCLONEFGC	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.4815600111799865	[305]	[94,125,103,70]	-9	hSpCas9	negative selection	7627423
116861835	116861858	8	+	27260156	LNCAPCLONEFGC	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.3326911058610573	[564]	[185,213,207,204]	-9	hSpCas9	negative selection	7691679
116857434	116857457	8	-	27260156	LNCAPCLONEFGC	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.485130803618728	[92]	[29,1,9,17]	-9	hSpCas9	negative selection	7691680
116861920	116861943	8	-	27260156	LNCAPCLONEFGC	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.8946545429228574	[124]	[40,19,143,53]	-8	hSpCas9	negative selection	7691681
116858421	116858444	8	+	27260156	PANC0327	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.4194906045825568	[654]	[1065,582,633,877]	6	hSpCas9	negative selection	7748672
116858412	116858435	8	-	27260156	PANC0327	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-4.734462342151636	[79]	[3,0,1,3]	-9	hSpCas9	negative selection	7748673
116863163	116863186	8	+	27260156	PANC0327	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	0.21305686491042275	[305]	[404,381,286,184]	3	hSpCas9	negative selection	7748674
116861835	116861858	8	+	27260156	PANC0327	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.7540073177538105	[564]	[544,232,280,159]	-8	hSpCas9	negative selection	7812930
116857434	116857457	8	-	27260156	PANC0327	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.4778177842385345	[92]	[2,1,7,1]	-9	hSpCas9	negative selection	7812931
116861920	116861943	8	-	27260156	PANC0327	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-1.0853041110373605	[124]	[85,29,69,28]	-8	hSpCas9	negative selection	7812932
116858421	116858444	8	+	27260156	NCIH2009	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.6212405448689208	[654]	[613,626,545]	-7	hSpCas9	negative selection	7869923
116858412	116858435	8	-	27260156	NCIH2009	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-4.03746011951814	[79]	[9,8,1]	-9	hSpCas9	negative selection	7869924
116863163	116863186	8	+	27260156	NCIH2009	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.224398257140721	[305]	[140,144,254]	-8	hSpCas9	negative selection	7869925
116861835	116861858	8	+	27260156	NCIH2009	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-2.4504426656714005	[564]	[114,210,99]	-9	hSpCas9	negative selection	7934181
116857434	116857457	8	-	27260156	NCIH2009	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.804964960045399	[92]	[4,4,3]	-9	hSpCas9	negative selection	7934182
116861920	116861943	8	-	27260156	NCIH2009	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-1.0656562419560047	[124]	[67,89,88]	-8	hSpCas9	negative selection	7934183
116858421	116858444	8	+	27260156	NCIH1373	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.5379931005568929	[654]	[1135,825,664,450]	5	hSpCas9	negative selection	7991174
116858412	116858435	8	-	27260156	NCIH1373	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.1161535343779425	[79]	[2,1,21,14]	-9	hSpCas9	negative selection	7991175
116863163	116863186	8	+	27260156	NCIH1373	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.8239137100189662	[305]	[151,189,321,24]	-7	hSpCas9	negative selection	7991176
116861835	116861858	8	+	27260156	NCIH1373	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.06534348664730749	[564]	[368,246,1357,109]	0	hSpCas9	negative selection	8055432
116857434	116857457	8	-	27260156	NCIH1373	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.2813477334652745	[92]	[1,9,0,1]	-9	hSpCas9	negative selection	8055433
116861920	116861943	8	-	27260156	NCIH1373	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.5001990985616964	[124]	[31,47,58,68]	-5	hSpCas9	negative selection	8055434
116858421	116858444	8	+	27260156	PATU8902	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-1.8474993542433737	[654]	[201,51,292,481]	-9	hSpCas9	negative selection	8112425
116858412	116858435	8	-	27260156	PATU8902	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-5.961936965741415	[79]	[0,2,1,0]	-9	hSpCas9	negative selection	8112426
116863163	116863186	8	+	27260156	PATU8902	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-2.207888166878603	[305]	[153,25,132,36]	-9	hSpCas9	negative selection	8112427
116861835	116861858	8	+	27260156	PATU8902	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.728040197259916	[564]	[357,217,177,203]	-8	hSpCas9	negative selection	8176683
116857434	116857457	8	-	27260156	PATU8902	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-6.44443943094182	[92]	[1,1,0,0]	-9	hSpCas9	negative selection	8176684
116861920	116861943	8	-	27260156	PATU8902	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.4751236120957776	[124]	[98,637,97,161]	5	hSpCas9	negative selection	8176685
116858421	116858444	8	+	27260156	PANC1	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.3214379316402853	[654]	[320,616,505,395]	-5	hSpCas9	negative selection	8233676
116858412	116858435	8	-	27260156	PANC1	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-4.900200772823143	[79]	[0,0,4,1]	-9	hSpCas9	negative selection	8233677
116863163	116863186	8	+	27260156	PANC1	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-1.5512081740773322	[305]	[98,109,88,66]	-9	hSpCas9	negative selection	8233678
116861835	116861858	8	+	27260156	PANC1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.3358945751097884	[564]	[164,287,162,172]	-9	hSpCas9	negative selection	8297934
116857434	116857457	8	-	27260156	PANC1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.784868660579102	[92]	[6,8,63,11]	-9	hSpCas9	negative selection	8297935
116861920	116861943	8	-	27260156	PANC1	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.23921254399306546	[124]	[112,49,69,115]	-4	hSpCas9	negative selection	8297936
116858421	116858444	8	+	27260156	PANC0813	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.30042855783828093	[654]	[618,605,620,649]	-5	hSpCas9	negative selection	8354927
116858412	116858435	8	-	27260156	PANC0813	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.588397744156394	[79]	[9,8,9,31]	-9	hSpCas9	negative selection	8354928
116863163	116863186	8	+	27260156	PANC0813	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.7839755829853818	[305]	[125,202,299,198]	-8	hSpCas9	negative selection	8354929
116861835	116861858	8	+	27260156	PANC0813	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.4987349004099242	[564]	[273,134,281,250]	-9	hSpCas9	negative selection	8419185
116857434	116857457	8	-	27260156	PANC0813	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.7138305555397464	[92]	[16,65,5,41]	-9	hSpCas9	negative selection	8419186
116861920	116861943	8	-	27260156	PANC0813	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.6587781663225099	[124]	[70,48,119,127]	-7	hSpCas9	negative selection	8419187
116858421	116858444	8	+	27260156	RDES	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.029449553987644705	[654]	[593,698,852,987]	0	hSpCas9	negative selection	8476178
116858412	116858435	8	-	27260156	RDES	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.7282727810853036	[79]	[35,39,15,11]	-9	hSpCas9	negative selection	8476179
116863163	116863186	8	+	27260156	RDES	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.9983449494504204	[305]	[116,209,237,140]	-9	hSpCas9	negative selection	8476180
116861835	116861858	8	+	27260156	RDES	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.6964273559426349	[564]	[275,404,436,520]	-8	hSpCas9	negative selection	8540436
116857434	116857457	8	-	27260156	RDES	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.8134340573748755	[92]	[43,8,49,14]	-9	hSpCas9	negative selection	8540437
116861920	116861943	8	-	27260156	RDES	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.6451896181302157	[124]	[71,85,112,100]	-8	hSpCas9	negative selection	8540438
116858421	116858444	8	+	27260156	PC3	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.35031606229396717	[654]	[370,558,1304,1465]	7	hSpCas9	negative selection	8597429
116858412	116858435	8	-	27260156	PC3	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.278390260280802	[79]	[17,8,21,15]	-9	hSpCas9	negative selection	8597430
116863163	116863186	8	+	27260156	PC3	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.31641118806355417	[305]	[229,116,551,177]	-6	hSpCas9	negative selection	8597431
116861835	116861858	8	+	27260156	PC3	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.6038758495687373	[564]	[231,400,498,424]	-8	hSpCas9	negative selection	8661687
116857434	116857457	8	-	27260156	PC3	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.2193762954741754	[92]	[22,75,45,16]	-9	hSpCas9	negative selection	8661688
116861920	116861943	8	-	27260156	PC3	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.21983063877244668	[124]	[177,97,132,127]	5	hSpCas9	negative selection	8661689
116858421	116858444	8	+	27260156	PATU8988T	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.2888081790824266	[654]	[335,603,658,475]	-5	hSpCas9	negative selection	8718680
116858412	116858435	8	-	27260156	PATU8988T	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.760088360983863	[79]	[1,0,33,6]	-9	hSpCas9	negative selection	8718681
116863163	116863186	8	+	27260156	PATU8988T	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	0.04621440340587746	[305]	[52,435,354,395]	0	hSpCas9	negative selection	8718682
116861835	116861858	8	+	27260156	PATU8988T	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.1402535891735504	[564]	[257,359,212,163]	-9	hSpCas9	negative selection	8782938
116857434	116857457	8	-	27260156	PATU8988T	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.6622249158325166	[92]	[24,7,1,21]	-9	hSpCas9	negative selection	8782939
116861920	116861943	8	-	27260156	PATU8988T	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.7191301341128122	[124]	[58,88,72,73]	-8	hSpCas9	negative selection	8782940
116858421	116858444	8	+	27260156	T47D	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.09253093717294825	[654]	[955,699,834,771]	2	hSpCas9	negative selection	8839931
116858412	116858435	8	-	27260156	T47D	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-1.614903971080781	[79]	[23,38,26,30]	-9	hSpCas9	negative selection	8839932
116863163	116863186	8	+	27260156	T47D	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.8223076556658175	[305]	[198,177,187,244]	-9	hSpCas9	negative selection	8839933
116861835	116861858	8	+	27260156	T47D	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.962195978312838	[564]	[341,328,301,380]	-9	hSpCas9	negative selection	8904189
116857434	116857457	8	-	27260156	T47D	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-1.4436625600626924	[92]	[40,43,34,38]	-9	hSpCas9	negative selection	8904190
116861920	116861943	8	-	27260156	T47D	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.21938242972080513	[124]	[149,105,102,143]	-5	hSpCas9	negative selection	8904191
116858421	116858444	8	+	27260156	SU8686	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.212531816675523	[654]	[601,603,402,623]	-4	hSpCas9	negative selection	8961182
116858412	116858435	8	-	27260156	SU8686	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-2.6409263937058105	[79]	[14,3,12,20]	-9	hSpCas9	negative selection	8961183
116863163	116863186	8	+	27260156	SU8686	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.9581528709177041	[305]	[197,214,79,107]	-8	hSpCas9	negative selection	8961184
116861835	116861858	8	+	27260156	SU8686	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9847873084383956	[564]	[238,287,397,198]	-8	hSpCas9	negative selection	9025440
116857434	116857457	8	-	27260156	SU8686	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.1561412931105632	[92]	[4,8,25,0]	-9	hSpCas9	negative selection	9025441
116861920	116861943	8	-	27260156	SU8686	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.31568965093453993	[124]	[35,142,100,122]	-5	hSpCas9	negative selection	9025442
116858421	116858444	8	+	27260156	SKES1	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.013185086979037364	[654]	[792,624,577,650]	0	hSpCas9	negative selection	9082433
116858412	116858435	8	-	27260156	SKES1	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.8434800160097313	[79]	[51,40,49,35]	-9	hSpCas9	negative selection	9082434
116863163	116863186	8	+	27260156	SKES1	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.9068211004541253	[305]	[177,151,184,137]	-9	hSpCas9	negative selection	9082435
116861835	116861858	8	+	27260156	SKES1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9150496943405211	[564]	[362,270,271,292]	-9	hSpCas9	negative selection	9146691
116857434	116857457	8	-	27260156	SKES1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-2.3924253690704793	[92]	[3,22,22,18]	-9	hSpCas9	negative selection	9146692
116861920	116861943	8	-	27260156	SKES1	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.018953372285546166	[124]	[343,65,49,62]	0	hSpCas9	negative selection	9146693
116858421	116858444	8	+	27260156	TOV112D	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.06762796910222552	[654]	[531,977,605,469]	-1	hSpCas9	negative selection	9203684
116858412	116858435	8	-	27260156	TOV112D	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.7083178404921426	[79]	[19,79,6,92]	-8	hSpCas9	negative selection	9203685
116863163	116863186	8	+	27260156	TOV112D	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.6772197928740273	[305]	[91,222,126,319]	-8	hSpCas9	negative selection	9203686
116861835	116861858	8	+	27260156	TOV112D	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.3209578386127522	[564]	[406,447,600,352]	-6	hSpCas9	negative selection	9267942
116857434	116857457	8	-	27260156	TOV112D	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.5139113840082716	[92]	[52,16,6,167]	-8	hSpCas9	negative selection	9267943
116861920	116861943	8	-	27260156	TOV112D	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.11325365150673417	[124]	[174,191,56,63]	-2	hSpCas9	negative selection	9267944
116858421	116858444	8	+	27260156	TC71	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	0.09720228199626535	[654]	[610,744,721,941]	2	hSpCas9	negative selection	9324935
116858412	116858435	8	-	27260156	TC71	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.7647151109349712	[79]	[46,21,70,61]	-9	hSpCas9	negative selection	9324936
116863163	116863186	8	+	27260156	TC71	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.5415358887999355	[305]	[236,220,211,231]	-9	hSpCas9	negative selection	9324937
116861835	116861858	8	+	27260156	TC71	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.555866211308602	[564]	[370,383,445,448]	-9	hSpCas9	negative selection	9389193
116857434	116857457	8	-	27260156	TC71	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.7834586222592459	[92]	[60,49,56,63]	-9	hSpCas9	negative selection	9389194
116861920	116861943	8	-	27260156	TC71	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	-0.0584690607208187	[124]	[160,133,122,93]	-1	hSpCas9	negative selection	9389195
116858421	116858444	8	+	27260156	TC32	viability	TCTGATTCAAGCTGAACTGCTGG	RAD21	ENSG00000164754	-0.37275569384847196	[654]	[511,329,483,605]	-6	hSpCas9	negative selection	9446186
116858412	116858435	8	-	27260156	TC32	viability	CAGCTTGAATCAGAGTAGAGTGG	RAD21	ENSG00000164754	-0.6856427613220637	[79]	[55,27,87,23]	-8	hSpCas9	negative selection	9446187
116863163	116863186	8	+	27260156	TC32	viability	CTTCATTACAGTCTGCAAGAAGG	RAD21	ENSG00000164754	-0.5260153422463512	[305]	[173,222,250,136]	-7	hSpCas9	negative selection	9446188
116861835	116861858	8	+	27260156	TC32	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.641497224784827	[564]	[314,274,376,411]	-8	hSpCas9	negative selection	9510444
116857434	116857457	8	-	27260156	TC32	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-0.8840999247496648	[92]	[25,66,39,46]	-9	hSpCas9	negative selection	9510445
116861920	116861943	8	-	27260156	TC32	viability	AGGTGTGGTTGACCTGCCTGAGG	RAD21	ENSG00000164754	0.249554318527218	[124]	[77,135,216,141]	4	hSpCas9	negative selection	9510446
116847515	116847538	8	-	27869803	HPAFII	viability after 27 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.19886788086523577	[571]	[231,286,NaN]	-1	hSpCas9	negative selection	9601093
116856234	116856257	8	+	27869803	HPAFII	viability after 27 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.461454183164398	[107]	[79,219,NaN]	9	hSpCas9	negative selection	9601094
116847515	116847538	8	-	27869803	HPAFII	viability after 15 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.13479930947050245	[571]	[644,506,NaN]	-1	hSpCas9	negative selection	9683542
116856234	116856257	8	+	27869803	HPAFII	viability after 15 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.0953550802193104	[107]	[284,224,NaN]	9	hSpCas9	negative selection	9683543
116847515	116847538	8	-	27869803	ASPC1	viability after 36 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.050930707584824764	[1069]	[414,456,241]	0	hSpCas9	negative selection	9765991
116856234	116856257	8	+	27869803	ASPC1	viability after 36 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.2593823341505219	[422]	[37,239,221]	2	hSpCas9	negative selection	9765992
116847515	116847538	8	-	27869803	PATU8988S	viability after 35 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	0.19296972662761935	[1062]	[661,315,NaN]	2	hSpCas9	negative selection	9848440
116856234	116856257	8	+	27869803	PATU8988S	viability after 35 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	-0.012697332177095344	[247]	[101,95,NaN]	0	hSpCas9	negative selection	9848441
116847515	116847538	8	-	27869803	PATU8988S	viability after 31 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.1676502445319431	[1062]	[390,359,NaN]	-2	hSpCas9	negative selection	9930889
116856234	116856257	8	+	27869803	PATU8988S	viability after 31 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	0.4296916807178217	[247]	[119,149,NaN]	5	hSpCas9	negative selection	9930890
116847515	116847538	8	-	27869803	HPAFII	viability after 35 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	0.14041614696181837	[571]	[194,458,NaN]	0	hSpCas9	negative selection	10013338
116856234	116856257	8	+	27869803	HPAFII	viability after 35 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	1.5496992682495805	[107]	[49,283,NaN]	9	hSpCas9	negative selection	10013339
116847515	116847538	8	-	27869803	HPAFII	viability after 31 days	TCATCGCAACACCTGGACCAAGG	RAD21	ENSG00000164754	-0.10881934143336403	[571]	[167,438,NaN]	0	hSpCas9	negative selection	10095787
116856234	116856257	8	+	27869803	HPAFII	viability after 31 days	ATGGTTGGCATTGGTTCAACGGG	RAD21	ENSG00000164754	2.036829263105286	[107]	[85,425,NaN]	9	hSpCas9	negative selection	10095788
116857434	116857457	8	-	28162770	P31FUJ	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.175316709753618	[122]	[0]	-9	hSpCas9	negative selection	10221673
116856697	116856720	8	+	28162770	P31FUJ	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.8975437791145326	[473]	[298]	-6	hSpCas9	negative selection	10221674
116854303	116854326	8	-	28162770	P31FUJ	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.5217798775004545	[302]	[61]	-8	hSpCas9	negative selection	10221675
116854244	116854267	8	-	28162770	P31FUJ	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-3.199013890958095	[210]	[26]	-9	hSpCas9	negative selection	10221676
116866606	116866629	8	-	28162770	P31FUJ	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.647839703693222	[63]	[2]	-9	hSpCas9	negative selection	10221677
116861835	116861858	8	+	28162770	P31FUJ	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.8041542736168816	[210]	[70]	-8	hSpCas9	negative selection	10221678
116856667	116856690	8	-	28162770	P31FUJ	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.29464783765156977	[434]	[626]	3	hSpCas9	negative selection	10221679
116852049	116852072	8	+	28162770	P31FUJ	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.34132666119254784	[344]	[319]	-3	hSpCas9	negative selection	10221680
116849011	116849034	8	-	28162770	P31FUJ	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.7669960943940692	[697]	[240]	-8	hSpCas9	negative selection	10221681
116857363	116857386	8	+	28162770	P31FUJ	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.8572930693221723	[591]	[191]	-8	hSpCas9	negative selection	10221682
116857434	116857457	8	-	28162770	TF1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10391039
116856697	116856720	8	+	28162770	TF1	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10391040
116854303	116854326	8	-	28162770	TF1	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10391041
116854244	116854267	8	-	28162770	TF1	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10391042
116866606	116866629	8	-	28162770	TF1	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10391043
116861835	116861858	8	+	28162770	TF1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10391044
116856667	116856690	8	-	28162770	TF1	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10391045
116852049	116852072	8	+	28162770	TF1	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10391046
116849011	116849034	8	-	28162770	TF1	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10391047
116857363	116857386	8	+	28162770	TF1	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10391048
116857434	116857457	8	-	28162770	SKM1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.044394119358453	[55]	[5]	-9	hSpCas9	negative selection	10560405
116856697	116856720	8	+	28162770	SKM1	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.0314550636509554	[110]	[95]	-6	hSpCas9	negative selection	10560406
116854303	116854326	8	-	28162770	SKM1	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.7950346504217363	[105]	[53]	-8	hSpCas9	negative selection	10560407
116854244	116854267	8	-	28162770	SKM1	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.3208075549934475	[64]	[22]	-8	hSpCas9	negative selection	10560408
116866606	116866629	8	-	28162770	SKM1	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.345563654079018	[22]	[0]	-9	hSpCas9	negative selection	10560409
116861835	116861858	8	+	28162770	SKM1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.3479233034203068	[59]	[134]	3	hSpCas9	negative selection	10560410
116856667	116856690	8	-	28162770	SKM1	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.09468627388951889	[89]	[148]	-1	hSpCas9	negative selection	10560411
116852049	116852072	8	+	28162770	SKM1	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.6769513652187226	[103]	[114]	-5	hSpCas9	negative selection	10560412
116849011	116849034	8	-	28162770	SKM1	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.994317246889312	[150]	[66]	-8	hSpCas9	negative selection	10560413
116857363	116857386	8	+	28162770	SKM1	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.1439297929093677	[119]	[95]	-7	hSpCas9	negative selection	10560414
116857434	116857457	8	-	28162770	SKM1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.044394119358453	[55]	[5]	-9	hSpCas9	negative selection	10729771
116856697	116856720	8	+	28162770	SKM1	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.0314550636509554	[110]	[95]	-6	hSpCas9	negative selection	10729772
116854303	116854326	8	-	28162770	SKM1	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.7950346504217363	[105]	[53]	-8	hSpCas9	negative selection	10729773
116854244	116854267	8	-	28162770	SKM1	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.3208075549934475	[64]	[22]	-8	hSpCas9	negative selection	10729774
116866606	116866629	8	-	28162770	SKM1	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.345563654079018	[22]	[0]	-9	hSpCas9	negative selection	10729775
116861835	116861858	8	+	28162770	SKM1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.3479233034203068	[59]	[134]	3	hSpCas9	negative selection	10729776
116856667	116856690	8	-	28162770	SKM1	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.09468627388951889	[89]	[148]	-1	hSpCas9	negative selection	10729777
116852049	116852072	8	+	28162770	SKM1	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.6769513652187226	[103]	[114]	-5	hSpCas9	negative selection	10729778
116849011	116849034	8	-	28162770	SKM1	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.994317246889312	[150]	[66]	-8	hSpCas9	negative selection	10729779
116857363	116857386	8	+	28162770	SKM1	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.1439297929093677	[119]	[95]	-7	hSpCas9	negative selection	10729780
116857434	116857457	8	-	28162770	PL21	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.9896849443906977	[145]	[3]	-9	hSpCas9	negative selection	10899137
116856697	116856720	8	+	28162770	PL21	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.10936922114397418	[346]	[139]	-1	hSpCas9	negative selection	10899138
116854303	116854326	8	-	28162770	PL21	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.495005803982259	[407]	[62]	-7	hSpCas9	negative selection	10899139
116854244	116854267	8	-	28162770	PL21	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-1.6239423939737323	[346]	[48]	-8	hSpCas9	negative selection	10899140
116866606	116866629	8	-	28162770	PL21	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.00931375113963	[73]	[0]	-9	hSpCas9	negative selection	10899141
116861835	116861858	8	+	28162770	PL21	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.37346302406728826	[252]	[84]	-3	hSpCas9	negative selection	10899142
116856667	116856690	8	-	28162770	PL21	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.13263586263503468	[266]	[105]	-1	hSpCas9	negative selection	10899143
116852049	116852072	8	+	28162770	PL21	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	0.17327300863663803	[270]	[132]	1	hSpCas9	negative selection	10899144
116849011	116849034	8	-	28162770	PL21	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-0.3451391847593541	[501]	[171]	-2	hSpCas9	negative selection	10899145
116857363	116857386	8	+	28162770	PL21	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.351034572775553	[421]	[35]	-8	hSpCas9	negative selection	10899146
116857434	116857457	8	-	28162770	P31FUJ	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.175316709753618	[122]	[0]	-9	hSpCas9	negative selection	11068503
116856697	116856720	8	+	28162770	P31FUJ	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.8975437791145326	[473]	[298]	-6	hSpCas9	negative selection	11068504
116854303	116854326	8	-	28162770	P31FUJ	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.5217798775004545	[302]	[61]	-8	hSpCas9	negative selection	11068505
116854244	116854267	8	-	28162770	P31FUJ	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-3.199013890958095	[210]	[26]	-9	hSpCas9	negative selection	11068506
116866606	116866629	8	-	28162770	P31FUJ	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.647839703693222	[63]	[2]	-9	hSpCas9	negative selection	11068507
116861835	116861858	8	+	28162770	P31FUJ	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-1.8041542736168816	[210]	[70]	-8	hSpCas9	negative selection	11068508
116856667	116856690	8	-	28162770	P31FUJ	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.29464783765156977	[434]	[626]	3	hSpCas9	negative selection	11068509
116852049	116852072	8	+	28162770	P31FUJ	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.34132666119254784	[344]	[319]	-3	hSpCas9	negative selection	11068510
116849011	116849034	8	-	28162770	P31FUJ	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.7669960943940692	[697]	[240]	-8	hSpCas9	negative selection	11068511
116857363	116857386	8	+	28162770	P31FUJ	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.8572930693221723	[591]	[191]	-8	hSpCas9	negative selection	11068512
116857434	116857457	8	-	28162770	OCIAML5	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-6.960591027642166	[68]	[0]	-9	hSpCas9	negative selection	11237869
116856697	116856720	8	+	28162770	OCIAML5	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.1239199235530628	[360]	[298]	-6	hSpCas9	negative selection	11237870
116854303	116854326	8	-	28162770	OCIAML5	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.296851413536893	[195]	[71]	-8	hSpCas9	negative selection	11237871
116854244	116854267	8	-	28162770	OCIAML5	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.523833899122426	[136]	[42]	-8	hSpCas9	negative selection	11237872
116866606	116866629	8	-	28162770	OCIAML5	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-6.406655422541634	[46]	[0]	-9	hSpCas9	negative selection	11237873
116861835	116861858	8	+	28162770	OCIAML5	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-2.299525547835218	[119]	[43]	-8	hSpCas9	negative selection	11237874
116856667	116856690	8	-	28162770	OCIAML5	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.26484809620247307	[212]	[319]	-2	hSpCas9	negative selection	11237875
116852049	116852072	8	+	28162770	OCIAML5	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.6422194028466627	[197]	[228]	-4	hSpCas9	negative selection	11237876
116849011	116849034	8	-	28162770	OCIAML5	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.589032165030203	[414]	[248]	-7	hSpCas9	negative selection	11237877
116857363	116857386	8	+	28162770	OCIAML5	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.7687381872651011	[369]	[195]	-7	hSpCas9	negative selection	11237878
116857434	116857457	8	-	28162770	EOL1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.47633166471165	[337]	[0]	-9	hSpCas9	negative selection	11407235
116856697	116856720	8	+	28162770	EOL1	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	0.6959911748242871	[429]	[366]	6	hSpCas9	negative selection	11407236
116854303	116854326	8	-	28162770	EOL1	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.1173881855968797	[732]	[88]	-8	hSpCas9	negative selection	11407237
116854244	116854267	8	-	28162770	EOL1	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-0.6066434727096409	[473]	[163]	-4	hSpCas9	negative selection	11407238
116866606	116866629	8	-	28162770	EOL1	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.908342242594207	[113]	[0]	-9	hSpCas9	negative selection	11407239
116861835	116861858	8	+	28162770	EOL1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	0.1233979990396385	[405]	[232]	1	hSpCas9	negative selection	11407240
116856667	116856690	8	-	28162770	EOL1	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.11292325468054665	[422]	[240]	1	hSpCas9	negative selection	11407241
116852049	116852072	8	+	28162770	EOL1	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.3854735566326535	[361]	[145]	-3	hSpCas9	negative selection	11407242
116849011	116849034	8	-	28162770	EOL1	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-0.8198145507302232	[716]	[213]	-5	hSpCas9	negative selection	11407243
116857363	116857386	8	+	28162770	EOL1	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.7207873471301034	[487]	[155]	-5	hSpCas9	negative selection	11407244
116857434	116857457	8	-	28162770	MOLM13	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.603572981012046	[268]	[0]	-9	hSpCas9	negative selection	11576601
116856697	116856720	8	+	28162770	MOLM13	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-1.2537078111984232	[497]	[150]	-6	hSpCas9	negative selection	11576602
116854303	116854326	8	-	28162770	MOLM13	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-1.4023967962394819	[573]	[156]	-6	hSpCas9	negative selection	11576603
116854244	116854267	8	-	28162770	MOLM13	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-0.9461885599729922	[500]	[187]	-5	hSpCas9	negative selection	11576604
116866606	116866629	8	-	28162770	MOLM13	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-6.402475338038826	[116]	[0]	-9	hSpCas9	negative selection	11576605
116861835	116861858	8	+	28162770	MOLM13	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.26724885957062067	[262]	[157]	-2	hSpCas9	negative selection	11576606
116856667	116856690	8	-	28162770	MOLM13	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.1423671393404875	[373]	[244]	-1	hSpCas9	negative selection	11576607
116852049	116852072	8	+	28162770	MOLM13	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-1.8790675078343058	[406]	[79]	-7	hSpCas9	negative selection	11576608
116849011	116849034	8	-	28162770	MOLM13	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-2.019225795778433	[683]	[121]	-7	hSpCas9	negative selection	11576609
116857363	116857386	8	+	28162770	MOLM13	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.0641242392276182	[641]	[110]	-7	hSpCas9	negative selection	11576610
116857434	116857457	8	-	28162770	HEL	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-3.6671164305864306	[237]	[11]	-9	hSpCas9	negative selection	11745967
116856697	116856720	8	+	28162770	HEL	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	0.15363634668671688	[392]	[279]	1	hSpCas9	negative selection	11745968
116854303	116854326	8	-	28162770	HEL	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.2192701649273174	[537]	[73]	-8	hSpCas9	negative selection	11745969
116854244	116854267	8	-	28162770	HEL	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.8682230872770225	[455]	[39]	-8	hSpCas9	negative selection	11745970
116866606	116866629	8	-	28162770	HEL	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.401655287358096	[98]	[2]	-9	hSpCas9	negative selection	11745971
116861835	116861858	8	+	28162770	HEL	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.12812716878413982	[243]	[142]	-1	hSpCas9	negative selection	11745972
116856667	116856690	8	-	28162770	HEL	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.16650567125846544	[381]	[217]	-1	hSpCas9	negative selection	11745973
116852049	116852072	8	+	28162770	HEL	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.5541936043451371	[336]	[146]	-4	hSpCas9	negative selection	11745974
116849011	116849034	8	-	28162770	HEL	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-0.009693251954181248	[579]	[368]	0	hSpCas9	negative selection	11745975
116857363	116857386	8	+	28162770	HEL	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-2.1030776797481145	[435]	[64]	-8	hSpCas9	negative selection	11745976
116857434	116857457	8	-	28162770	MV411	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.037964668079473	[155]	[0]	-9	hSpCas9	negative selection	11915333
116856697	116856720	8	+	28162770	MV411	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.5668478651834452	[312]	[177]	-4	hSpCas9	negative selection	11915334
116854303	116854326	8	-	28162770	MV411	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.745028776531817	[381]	[47]	-9	hSpCas9	negative selection	11915335
116854244	116854267	8	-	28162770	MV411	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.0597439587354005	[291]	[58]	-8	hSpCas9	negative selection	11915336
116866606	116866629	8	-	28162770	MV411	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.796956568575678	[65]	[0]	-9	hSpCas9	negative selection	11915337
116861835	116861858	8	+	28162770	MV411	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.5167495121184553	[213]	[125]	-4	hSpCas9	negative selection	11915338
116856667	116856690	8	-	28162770	MV411	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.22444590815654614	[252]	[248]	2	hSpCas9	negative selection	11915339
116852049	116852072	8	+	28162770	MV411	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.12424357930168661	[294]	[227]	-1	hSpCas9	negative selection	11915340
116849011	116849034	8	-	28162770	MV411	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.1611449263587688	[445]	[167]	-6	hSpCas9	negative selection	11915341
116857363	116857386	8	+	28162770	MV411	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.019348989912126	[384]	[159]	-6	hSpCas9	negative selection	11915342
116857434	116857457	8	-	28162770	MONOMAC1	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-5.32631986400452	[104]	[2]	-9	hSpCas9	negative selection	12084699
116856697	116856720	8	+	28162770	MONOMAC1	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.0645865510359041	[155]	[170]	0	hSpCas9	negative selection	12084700
116854303	116854326	8	-	28162770	MONOMAC1	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-0.991613164395855	[280]	[161]	-7	hSpCas9	negative selection	12084701
116854244	116854267	8	-	28162770	MONOMAC1	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-1.8654153559683473	[177]	[55]	-8	hSpCas9	negative selection	12084702
116866606	116866629	8	-	28162770	MONOMAC1	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-3.634442159366852	[64]	[5]	-9	hSpCas9	negative selection	12084703
116861835	116861858	8	+	28162770	MONOMAC1	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.9300979867698438	[122]	[73]	-6	hSpCas9	negative selection	12084704
116856667	116856690	8	-	28162770	MONOMAC1	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.45657300061117273	[170]	[268]	4	hSpCas9	negative selection	12084705
116852049	116852072	8	+	28162770	MONOMAC1	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.5833915916343126	[165]	[126]	-5	hSpCas9	negative selection	12084706
116849011	116849034	8	-	28162770	MONOMAC1	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.0925675805035244	[252]	[135]	-7	hSpCas9	negative selection	12084707
116857363	116857386	8	+	28162770	MONOMAC1	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.099189523661409	[227]	[121]	-7	hSpCas9	negative selection	12084708
116857434	116857457	8	-	28162770	OCIAML2	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-7.640554826684474	[35]	[0]	-9	hSpCas9	negative selection	12254065
116856697	116856720	8	+	28162770	OCIAML2	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	-0.30070482379984886	[55]	[251]	-2	hSpCas9	negative selection	12254066
116854303	116854326	8	-	28162770	OCIAML2	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.066732883568518	[64]	[85]	-8	hSpCas9	negative selection	12254067
116854244	116854267	8	-	28162770	OCIAML2	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-1.9103293787552742	[58]	[86]	-8	hSpCas9	negative selection	12254068
116866606	116866629	8	-	28162770	OCIAML2	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-4.885667324521005	[15]	[2]	-9	hSpCas9	negative selection	12254069
116861835	116861858	8	+	28162770	OCIAML2	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.2706922547334093	[36]	[169]	-2	hSpCas9	negative selection	12254070
116856667	116856690	8	-	28162770	OCIAML2	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	0.10845610914232551	[40]	[244]	1	hSpCas9	negative selection	12254071
116852049	116852072	8	+	28162770	OCIAML2	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	-0.9470678691851484	[55]	[160]	-6	hSpCas9	negative selection	12254072
116849011	116849034	8	-	28162770	OCIAML2	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.84146752061047	[74]	[115]	-8	hSpCas9	negative selection	12254073
116857363	116857386	8	+	28162770	OCIAML2	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-1.936293397590973	[86]	[125]	-8	hSpCas9	negative selection	12254074
116857434	116857457	8	-	28162770	OCIAML3	viability	GATCGTGAGATAATGAGAGAAGG	RAD21	ENSG00000164754	-4.246084336903857	[43]	[6]	-9	hSpCas9	negative selection	12423431
116856697	116856720	8	+	28162770	OCIAML3	viability	ACATCACCCCTGCCTCAGAGAGG	RAD21	ENSG00000164754	0.24651414566864027	[85]	[307]	2	hSpCas9	negative selection	12423432
116854303	116854326	8	-	28162770	OCIAML3	viability	ATGATGTGGAAAGAGACAGGAGG	RAD21	ENSG00000164754	-2.219159231161018	[90]	[58]	-8	hSpCas9	negative selection	12423433
116854244	116854267	8	-	28162770	OCIAML3	viability	GTGGAATAACAGACTACTGAAGG	RAD21	ENSG00000164754	-2.773331339768725	[76]	[33]	-9	hSpCas9	negative selection	12423434
116866606	116866629	8	-	28162770	OCIAML3	viability	GTGTAATTTAGAGAGCAGCGTGG	RAD21	ENSG00000164754	-5.348895142487632	[26]	[1]	-9	hSpCas9	negative selection	12423435
116861835	116861858	8	+	28162770	OCIAML3	viability	ACATACTCTAAGTCAGGCAGTGG	RAD21	ENSG00000164754	-0.4265508944726004	[64]	[145]	-3	hSpCas9	negative selection	12423436
116856667	116856690	8	-	28162770	OCIAML3	viability	GCAGCCTGCACATGACGATATGG	RAD21	ENSG00000164754	-0.5784107852731446	[91]	[185]	-4	hSpCas9	negative selection	12423437
116852049	116852072	8	+	28162770	OCIAML3	viability	CCATCACTGACTCCTGGAGGCGG	RAD21	ENSG00000164754	1.1591551813698444	[61]	[417]	8	hSpCas9	negative selection	12423438
116849011	116849034	8	-	28162770	OCIAML3	viability	TCAGGATGAAGATGCATCAGGGG	RAD21	ENSG00000164754	-1.3417339293281536	[156]	[186]	-7	hSpCas9	negative selection	12423439
116857363	116857386	8	+	28162770	OCIAML3	viability	TCTGTTCAGACTCTAATAGGAGG	RAD21	ENSG00000164754	-0.6062859701026001	[117]	[233]	-4	hSpCas9	negative selection	12423440