Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9693
• Symbol: RAPGEF2
• Description: Rap guanine nucleotide exchange factor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/RAPGEF2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
159353897	159353920	4	+	26472758	Jiyoye	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.4964427196029606	[140]	[149]	4	hSpCas9	negative selection	133581
159323581	159323604	4	+	26472758	Jiyoye	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	-0.1534029605883238	[263]	[178]	-1	hSpCas9	negative selection	133582
159355953	159355976	4	+	26472758	Jiyoye	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	5.361371691892748	[0]	[30]	9	hSpCas9	negative selection	133583
159304387	159304410	4	-	26472758	Jiyoye	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.6944573335863446	[58]	[71]	5	hSpCas9	negative selection	133584
159304397	159304420	4	-	26472758	Jiyoye	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	6.051031571280598	[0]	[49]	9	hSpCas9	negative selection	133585
159314626	159314649	4	+	26472758	Jiyoye	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.771161859752639	[128]	[56]	-5	hSpCas9	negative selection	133586
159314716	159314739	4	+	26472758	Jiyoye	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.3565493084359055	[57]	[55]	2	hSpCas9	negative selection	133587
159346905	159346928	4	+	26472758	Jiyoye	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.3697006760872105	[77]	[75]	2	hSpCas9	negative selection	133588
159346939	159346962	4	-	26472758	Jiyoye	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.5877476271476944	[104]	[118]	4	hSpCas9	negative selection	133589
159352835	159352858	4	+	26472758	Jiyoye	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.009047660737112162	[310]	[235]	0	hSpCas9	negative selection	133590
159353897	159353920	4	+	26472758	KBM7	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.7617493569659657	[509,533]	[538,311]	8	hSpCas9	negative selection	324699
159323581	159323604	4	+	26472758	KBM7	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.7105292126681538	[811,842]	[621,657]	7	hSpCas9	negative selection	324700
159355953	159355976	4	+	26472758	KBM7	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.17443928571247258	[123,96]	[82,35]	1	hSpCas9	negative selection	324701
159304387	159304410	4	-	26472758	KBM7	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.047517952215877735	[499,335]	[189,208]	0	hSpCas9	negative selection	324702
159304397	159304420	4	-	26472758	KBM7	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.5141996207984143	[356,217]	[115,71]	-4	hSpCas9	negative selection	324703
159314626	159314649	4	+	26472758	KBM7	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.032219525138808325	[502,270]	[194,153]	0	hSpCas9	negative selection	324704
159314716	159314739	4	+	26472758	KBM7	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.08674366327906136	[247,207]	[143,85]	0	hSpCas9	negative selection	324705
159346905	159346928	4	+	26472758	KBM7	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.1555900523061921	[424,383]	[281,148]	1	hSpCas9	negative selection	324706
159346939	159346962	4	-	26472758	KBM7	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.7188515168941096	[405,326]	[321,245]	7	hSpCas9	negative selection	324707
159352835	159352858	4	+	26472758	KBM7	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	-0.22913460954285703	[915,1052]	[443,359]	-2	hSpCas9	negative selection	324708
159353897	159353920	4	+	26472758	Raji	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	1.1544686714433408	[210]	[108]	8	hSpCas9	negative selection	515817
159323581	159323604	4	+	26472758	Raji	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.34809085409012985	[368]	[108]	3	hSpCas9	negative selection	515818
159355953	159355976	4	+	26472758	Raji	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	1.1480255198709455	[34]	[17]	8	hSpCas9	negative selection	515819
159304387	159304410	4	-	26472758	Raji	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.29860882430223756	[158]	[29]	-3	hSpCas9	negative selection	515820
159304397	159304420	4	-	26472758	Raji	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.0396389287377652	[108]	[25]	0	hSpCas9	negative selection	515821
159314626	159314649	4	+	26472758	Raji	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.04037008507009268	[225]	[50]	0	hSpCas9	negative selection	515822
159314716	159314739	4	+	26472758	Raji	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.24231311545970813	[152]	[41]	2	hSpCas9	negative selection	515823
159346905	159346928	4	+	26472758	Raji	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.7047510569855364	[192]	[72]	6	hSpCas9	negative selection	515824
159346939	159346962	4	-	26472758	Raji	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	-0.22030382880244775	[250]	[49]	-2	hSpCas9	negative selection	515825
159352835	159352858	4	+	26472758	Raji	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	1.118879174211429	[374]	[188]	8	hSpCas9	negative selection	515826
159353897	159353920	4	+	26472758	K562	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.9480257248862222	[384]	[626]	7	hSpCas9	negative selection	706935
159323581	159323604	4	+	26472758	K562	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.6194158667439398	[821]	[1065]	5	hSpCas9	negative selection	706936
159355953	159355976	4	+	26472758	K562	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.12737930647622742	[76]	[70]	0	hSpCas9	negative selection	706937
159304387	159304410	4	-	26472758	K562	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.4370638056088427	[258]	[295]	3	hSpCas9	negative selection	706938
159304397	159304420	4	-	26472758	K562	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.19670800048105797	[185]	[136]	-1	hSpCas9	negative selection	706939
159314626	159314649	4	+	26472758	K562	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	1.582399227839175	[285]	[722]	9	hSpCas9	negative selection	706940
159314716	159314739	4	+	26472758	K562	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	1.3085490650861624	[208]	[436]	9	hSpCas9	negative selection	706941
159346905	159346928	4	+	26472758	K562	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	1.3289065981368573	[256]	[544]	9	hSpCas9	negative selection	706942
159346939	159346962	4	-	26472758	K562	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.5818136238995799	[333]	[421]	5	hSpCas9	negative selection	706943
159352835	159352858	4	+	26472758	K562	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.46345604274451446	[737]	[858]	3	hSpCas9	negative selection	706944
159304398	159304421	4	-	26627737	DLD1	viability	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.2742419778356052	[823]	[327,289,314]	3	hSpCas9	negative selection	824306
159314688	159314711	4	+	26627737	DLD1	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.24581422290121302	[260]	[105,64,114]	2	hSpCas9	negative selection	824307
159322434	159322457	4	+	26627737	DLD1	viability	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.601794531838386	[696]	[344,377,278]	6	hSpCas9	negative selection	824308
159329960	159329983	4	+	26627737	DLD1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.7014534312623877	[932]	[400,700,349]	7	hSpCas9	negative selection	824310
159330429	159330452	4	+	26627737	DLD1	viability	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.30161685228563023	[267]	[91,124,94]	3	hSpCas9	negative selection	824311
159331738	159331761	4	+	26627737	DLD1	viability	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.17710968210449557	[446]	[109,212,153]	1	hSpCas9	negative selection	824312
159304398	159304421	4	-	26627737	GBM cells	viability after 5 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.08546733910119975	[622]	[344,363]	1	hSpCas9	negative selection	906621
159314688	159314711	4	+	26627737	GBM cells	viability after 5 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.8229650216523869	[116]	[102,118]	9	hSpCas9	negative selection	906622
159322434	159322457	4	+	26627737	GBM cells	viability after 5 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.06304676409514043	[523]	[290,246]	-1	hSpCas9	negative selection	906623
159329960	159329983	4	+	26627737	GBM cells	viability after 5 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.20834753596830957	[718]	[439,450]	3	hSpCas9	negative selection	906625
159330429	159330452	4	+	26627737	GBM cells	viability after 5 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.13837980958107504	[215]	[128,125]	2	hSpCas9	negative selection	906626
159331738	159331761	4	+	26627737	GBM cells	viability after 5 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.1917709233145135	[390]	[236,241]	3	hSpCas9	negative selection	906627
159304398	159304421	4	-	26627737	GBM cells	viability after 13 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.16282790265074487	[622]	[448,320]	2	hSpCas9	negative selection	988936
159314688	159314711	4	+	26627737	GBM cells	viability after 13 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.8335123859656104	[116]	[84,135]	8	hSpCas9	negative selection	988937
159322434	159322457	4	+	26627737	GBM cells	viability after 13 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.03650520404843327	[523]	[311,274]	0	hSpCas9	negative selection	988938
159329960	159329983	4	+	26627737	GBM cells	viability after 13 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.16102329923080294	[718]	[444,428]	2	hSpCas9	negative selection	988940
159330429	159330452	4	+	26627737	GBM cells	viability after 13 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.5182696278410897	[215]	[222,122]	6	hSpCas9	negative selection	988941
159331738	159331761	4	+	26627737	GBM cells	viability after 13 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.2011572152295955	[390]	[226,149]	-2	hSpCas9	negative selection	988942
159304398	159304421	4	-	26627737	GBM cells	viability after 21 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.28838441330926234	[622]	[451,377]	3	hSpCas9	negative selection	1071251
159314688	159314711	4	+	26627737	GBM cells	viability after 21 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	1.0172385261355676	[116]	[124,131]	8	hSpCas9	negative selection	1071252
159322434	159322457	4	+	26627737	GBM cells	viability after 21 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.1371875976467496	[523]	[322,303]	1	hSpCas9	negative selection	1071253
159329960	159329983	4	+	26627737	GBM cells	viability after 21 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.02135809638060726	[718]	[422,349]	0	hSpCas9	negative selection	1071255
159330429	159330452	4	+	26627737	GBM cells	viability after 21 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.317339426505315	[215]	[89,97]	-3	hSpCas9	negative selection	1071256
159331738	159331761	4	+	26627737	GBM cells	viability after 21 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.12642359779794488	[390]	[203,185]	-1	hSpCas9	negative selection	1071257
159304398	159304421	4	-	26627737	RPE1	viability after 9 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.2679530518806412	[2035]	[431,654]	-2	hSpCas9	negative selection	1153566
159314688	159314711	4	+	26627737	RPE1	viability after 9 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.6488282125865786	[442]	[254,168]	4	hSpCas9	negative selection	1153567
159322434	159322457	4	+	26627737	RPE1	viability after 9 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.815479753821166	[1062]	[486,712]	5	hSpCas9	negative selection	1153568
159329960	159329983	4	+	26627737	RPE1	viability after 9 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.2627139475940061	[3177]	[758,919]	-2	hSpCas9	negative selection	1153570
159330429	159330452	4	+	26627737	RPE1	viability after 9 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.5046229086462378	[597]	[79,198]	-4	hSpCas9	negative selection	1153571
159331738	159331761	4	+	26627737	RPE1	viability after 9 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.4118228098675697	[806]	[267,423]	3	hSpCas9	negative selection	1153572
159304398	159304421	4	-	26627737	RPE1	viability after 12 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.44661632181216593	[2035]	[413,387]	-3	hSpCas9	negative selection	1235881
159314688	159314711	4	+	26627737	RPE1	viability after 12 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.3789438816442058	[442]	[197,108]	2	hSpCas9	negative selection	1235882
159322434	159322457	4	+	26627737	RPE1	viability after 12 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.8775737888160866	[1062]	[548,498]	5	hSpCas9	negative selection	1235883
159329960	159329983	4	+	26627737	RPE1	viability after 12 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.07891747651792747	[3177]	[769,848]	0	hSpCas9	negative selection	1235885
159330429	159330452	4	+	26627737	RPE1	viability after 12 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.5818078788281627	[597]	[67,148]	-4	hSpCas9	negative selection	1235886
159331738	159331761	4	+	26627737	RPE1	viability after 12 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.1098751039830747	[806]	[266,198]	0	hSpCas9	negative selection	1235887
159304398	159304421	4	-	26627737	RPE1	viability after 15 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-1.2426922168721979	[2035]	[249,236]	-6	hSpCas9	negative selection	1318196
159314688	159314711	4	+	26627737	RPE1	viability after 15 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.5259707726168042	[442]	[239,122]	3	hSpCas9	negative selection	1318197
159322434	159322457	4	+	26627737	RPE1	viability after 15 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.7660368784453622	[1062]	[546,476]	5	hSpCas9	negative selection	1318198
159329960	159329983	4	+	26627737	RPE1	viability after 15 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.2254251085812804	[3177]	[940,602]	-1	hSpCas9	negative selection	1318200
159330429	159330452	4	+	26627737	RPE1	viability after 15 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-1.4497948356119756	[597]	[37,84]	-7	hSpCas9	negative selection	1318201
159331738	159331761	4	+	26627737	RPE1	viability after 15 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.12281050259170606	[806]	[200,217]	-1	hSpCas9	negative selection	1318202
159304398	159304421	4	-	26627737	RPE1	viability after 18 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.7626790416575395	[2035]	[435,203]	-5	hSpCas9	negative selection	1400511
159314688	159314711	4	+	26627737	RPE1	viability after 18 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.8397806419215768	[442]	[285,136]	5	hSpCas9	negative selection	1400512
159322434	159322457	4	+	26627737	RPE1	viability after 18 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.14554736515353156	[1062]	[282,353]	0	hSpCas9	negative selection	1400513
159329960	159329983	4	+	26627737	RPE1	viability after 18 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.5614877882298959	[3177]	[526,638]	-4	hSpCas9	negative selection	1400515
159330429	159330452	4	+	26627737	RPE1	viability after 18 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-1.3160738953711533	[597]	[73,54]	-7	hSpCas9	negative selection	1400516
159331738	159331761	4	+	26627737	RPE1	viability after 18 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.5492192234107941	[806]	[323,312]	3	hSpCas9	negative selection	1400517
159304398	159304421	4	-	26627737	HeLa	viability after 8 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.07902378185722769	[827]	[453,324,378]	0	hSpCas9	negative selection	1482826
159314688	159314711	4	+	26627737	HeLa	viability after 8 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-1.385546264115959	[389]	[50,78,61]	-8	hSpCas9	negative selection	1482827
159322434	159322457	4	+	26627737	HeLa	viability after 8 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.6735352571640398	[444]	[393,193,353]	6	hSpCas9	negative selection	1482828
159329960	159329983	4	+	26627737	HeLa	viability after 8 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.32804137283087487	[840]	[641,489,297]	3	hSpCas9	negative selection	1482830
159330429	159330452	4	+	26627737	HeLa	viability after 8 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.06136919282431175	[212]	[55,36,181]	0	hSpCas9	negative selection	1482831
159331738	159331761	4	+	26627737	HeLa	viability after 8 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.3264020360468635	[422]	[249,280,169]	3	hSpCas9	negative selection	1482832
159304398	159304421	4	-	26627737	HeLa	viability after 12 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.33944832441764694	[827]	[741,289,290]	3	hSpCas9	negative selection	1565141
159314688	159314711	4	+	26627737	HeLa	viability after 12 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.4869491690465833	[389]	[116,58,174]	-4	hSpCas9	negative selection	1565142
159322434	159322457	4	+	26627737	HeLa	viability after 12 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.1274786205829813	[444]	[161,139,305]	1	hSpCas9	negative selection	1565143
159329960	159329983	4	+	26627737	HeLa	viability after 12 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.43934959310434096	[840]	[244,454,708]	4	hSpCas9	negative selection	1565145
159330429	159330452	4	+	26627737	HeLa	viability after 12 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.16911318910548556	[212]	[89,57,152]	1	hSpCas9	negative selection	1565146
159331738	159331761	4	+	26627737	HeLa	viability after 12 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.34511529838593846	[422]	[193,113,108]	-3	hSpCas9	negative selection	1565147
159304398	159304421	4	-	26627737	HeLa	viability after 15 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.5017044347515041	[827]	[260,775,390]	4	hSpCas9	negative selection	1647456
159314688	159314711	4	+	26627737	HeLa	viability after 15 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.6554204014024086	[389]	[126,62,112]	-5	hSpCas9	negative selection	1647457
159322434	159322457	4	+	26627737	HeLa	viability after 15 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.5008385826418341	[444]	[231,224,316]	4	hSpCas9	negative selection	1647458
159329960	159329983	4	+	26627737	HeLa	viability after 15 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.0465645209076202	[840]	[312,177,517]	0	hSpCas9	negative selection	1647460
159330429	159330452	4	+	26627737	HeLa	viability after 15 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.138881183910201	[212]	[81,53,101]	-1	hSpCas9	negative selection	1647461
159331738	159331761	4	+	26627737	HeLa	viability after 15 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.531028160289404	[422]	[154,131,65]	-5	hSpCas9	negative selection	1647462
159304398	159304421	4	-	26627737	HeLa	viability after 18 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.523970591457608	[827]	[173,661,390]	4	hSpCas9	negative selection	1729771
159314688	159314711	4	+	26627737	HeLa	viability after 18 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.6201357641808819	[389]	[86,55,112]	-5	hSpCas9	negative selection	1729772
159322434	159322457	4	+	26627737	HeLa	viability after 18 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.48948393507643206	[444]	[151,185,316]	4	hSpCas9	negative selection	1729773
159329960	159329983	4	+	26627737	HeLa	viability after 18 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.061234847534425096	[840]	[202,147,517]	0	hSpCas9	negative selection	1729775
159330429	159330452	4	+	26627737	HeLa	viability after 18 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.16156740125040836	[212]	[57,37,101]	-1	hSpCas9	negative selection	1729776
159331738	159331761	4	+	26627737	HeLa	viability after 18 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.5576566594143999	[422]	[99,108,65]	-5	hSpCas9	negative selection	1729777
159304398	159304421	4	-	26627737	HCT116	viability after 6 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.19544169963213398	[1539]	[184,225]	-1	hSpCas9	negative selection	1812086
159314688	159314711	4	+	26627737	HCT116	viability after 6 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.3453670302034847	[357]	[120,1]	-2	hSpCas9	negative selection	1812087
159322434	159322457	4	+	26627737	HCT116	viability after 6 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	1.9292526059303174	[866]	[1104,195]	8	hSpCas9	negative selection	1812088
159329960	159329983	4	+	26627737	HCT116	viability after 6 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.8604456025547229	[1583]	[435,460]	5	hSpCas9	negative selection	1812090
159330429	159330452	4	+	26627737	HCT116	viability after 6 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-4.2874026640573994	[540]	[4,3]	-9	hSpCas9	negative selection	1812091
159331738	159331761	4	+	26627737	HCT116	viability after 6 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.2365505782680154	[1001]	[124,218]	1	hSpCas9	negative selection	1812092
159304398	159304421	4	-	26627737	HCT116	viability after 8 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.25396217357369877	[808]	[334,346,437]	-3	hSpCas9	negative selection	1894401
159314688	159314711	4	+	26627737	HCT116	viability after 8 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.3052762824633488	[121]	[102,99,46]	3	hSpCas9	negative selection	1894402
159322434	159322457	4	+	26627737	HCT116	viability after 8 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.3079154607202901	[696]	[427,288,216]	-4	hSpCas9	negative selection	1894403
159329960	159329983	4	+	26627737	HCT116	viability after 8 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.3868796925754221	[1034]	[281,608,414]	-4	hSpCas9	negative selection	1894405
159330429	159330452	4	+	26627737	HCT116	viability after 8 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.4060218267476801	[208]	[195,145,116]	4	hSpCas9	negative selection	1894406
159331738	159331761	4	+	26627737	HCT116	viability after 8 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.1121617749369363	[437]	[276,182,210]	-1	hSpCas9	negative selection	1894407
159304398	159304421	4	-	26627737	HCT116	viability after 9 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.5047415057548927	[1539]	[850,371]	4	hSpCas9	negative selection	1976716
159314688	159314711	4	+	26627737	HCT116	viability after 9 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.5197373312396146	[357]	[126,18]	-4	hSpCas9	negative selection	1976717
159322434	159322457	4	+	26627737	HCT116	viability after 9 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.9127194476616605	[866]	[508,377]	6	hSpCas9	negative selection	1976718
159329960	159329983	4	+	26627737	HCT116	viability after 9 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.09097880100533229	[1583]	[438,363]	0	hSpCas9	negative selection	1976720
159330429	159330452	4	+	26627737	HCT116	viability after 9 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.16316696667183386	[540]	[271,15]	-1	hSpCas9	negative selection	1976721
159331738	159331761	4	+	26627737	HCT116	viability after 9 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.49614907445660394	[1001]	[225,160]	-4	hSpCas9	negative selection	1976722
159304398	159304421	4	-	26627737	HCT116	viability after 12 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.08888080660156739	[808]	[320,557,330]	-1	hSpCas9	negative selection	2059031
159314688	159314711	4	+	26627737	HCT116	viability after 12 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.5909416316128588	[121]	[96,109,82]	5	hSpCas9	negative selection	2059032
159322434	159322457	4	+	26627737	HCT116	viability after 12 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.25412118434094433	[696]	[353,253,307]	-3	hSpCas9	negative selection	2059033
159329960	159329983	4	+	26627737	HCT116	viability after 12 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.5935154858821963	[1034]	[364,359,355]	-6	hSpCas9	negative selection	2059035
159330429	159330452	4	+	26627737	HCT116	viability after 12 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.6027819737205238	[208]	[176,145,175]	5	hSpCas9	negative selection	2059036
159331738	159331761	4	+	26627737	HCT116	viability after 12 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.14198862149021318	[437]	[193,326,247]	1	hSpCas9	negative selection	2059037
159304398	159304421	4	-	26627737	HCT116	viability after 15 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.08167637214435364	[808]	[656,361,325]	-1	hSpCas9	negative selection	2141346
159314688	159314711	4	+	26627737	HCT116	viability after 15 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.4534646651018186	[121]	[88,103,93]	4	hSpCas9	negative selection	2141347
159322434	159322457	4	+	26627737	HCT116	viability after 15 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.09979352012220533	[696]	[508,330,297]	-1	hSpCas9	negative selection	2141348
159329960	159329983	4	+	26627737	HCT116	viability after 15 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.4594057431740155	[1034]	[475,376,448]	-5	hSpCas9	negative selection	2141350
159330429	159330452	4	+	26627737	HCT116	viability after 15 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.3469893103728766	[208]	[211,82,169]	3	hSpCas9	negative selection	2141351
159331738	159331761	4	+	26627737	HCT116	viability after 15 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.31435870972305646	[437]	[252,153,205]	-3	hSpCas9	negative selection	2141352
159304398	159304421	4	-	26627737	HCT116	viability after 18 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.07134099705253028	[808]	[440,456,327]	0	hSpCas9	negative selection	2223661
159314688	159314711	4	+	26627737	HCT116	viability after 18 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	1.1570037682459597	[121]	[173,118,100]	8	hSpCas9	negative selection	2223662
159322434	159322457	4	+	26627737	HCT116	viability after 18 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.007361283336426938	[696]	[424,321,255]	0	hSpCas9	negative selection	2223663
159329960	159329983	4	+	26627737	HCT116	viability after 18 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.03464678171265878	[1034]	[552,354,569]	0	hSpCas9	negative selection	2223665
159330429	159330452	4	+	26627737	HCT116	viability after 18 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.40483747108542106	[208]	[164,97,140]	3	hSpCas9	negative selection	2223666
159331738	159331761	4	+	26627737	HCT116	viability after 18 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.38784531234672054	[437]	[138,166,179]	-4	hSpCas9	negative selection	2223667
159184010	159184033	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGATAGTTTGCTGAGAATGATGG	RAPGEF2	ENSG00000109756	2.501009302608253	[331,214]	[286,396]	8	dCas9-VP64	positive selection	2387671
159140880	159140903	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGTAGTGGCGCGATCTCAG	RAPGEF2	ENSG00000109756	3.1722237697093507	[103,9]	[210,6]	8	dCas9-VP64	positive selection	2392246
159281101	159281124	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTCGGGAGACTGAGGCAGG	RAPGEF2	ENSG00000109756	-0.7498462491276636	[113,13]	[10,3]	-4	dCas9-VP64	positive selection	2408598
159130951	159130974	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGGGCAG	RAPGEF2	ENSG00000109756	-1.8840232515636643	[4,58]	[0,1]	-9	dCas9-VP64	positive selection	2423253
159267666	159267689	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACAAGGGTATTAACAATGCTTGG	RAPGEF2	ENSG00000109756	3.583468693819118	[127,150]	[391,345]	9	dCas9-VP64	positive selection	2443669
159267684	159267707	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTGGCTGAATGCTAGAGCCTGG	RAPGEF2	ENSG00000109756	-0.7390969548921478	[166,212]	[25,22]	-4	dCas9-VP64	positive selection	2443670
159267649	159267672	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGATTGCAGATGAAACAAGG	RAPGEF2	ENSG00000109756	1.3954426582958193	[51,34]	[40,7]	5	dCas9-VP64	positive selection	2443671
159214986	159215009	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATACCAACTACTTGG	RAPGEF2	ENSG00000109756	-0.20904487410036232	[411,186]	[69,40]	-1	dCas9-VP64	positive selection	2448705
159130823	159130846	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGGAGGCTGTGG	RAPGEF2	ENSG00000109756	1.7381005027272516	[41,48]	[11,55]	6	dCas9-VP64	positive selection	2458188
159234967	159234990	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTAGGAGTTCGAGACCAGCCTAG	RAPGEF2	ENSG00000109756	-0.8844378867613548	[237,84]	[20,15]	-5	dCas9-VP64	positive selection	2461515
159131183	159131206	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCGCAACCTCCGCCTCCTAG	RAPGEF2	ENSG00000109756	-0.9705266312095737	[543,439]	[39,70]	-6	dCas9-VP64	positive selection	2469165
159131202	159131225	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCAGAATCGCTTGAACCTAG	RAPGEF2	ENSG00000109756	4.376878119565056	[324,400]	[1478,1870]	9	dCas9-VP64	positive selection	2470863
159209123	159209146	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCTGCCTGAG	RAPGEF2	ENSG00000109756	-1.0260640950785338	[143,176]	[21,11]	-6	dCas9-VP64	positive selection	2475206
159184010	159184033	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGATAGTTTGCTGAGAATGATGG	RAPGEF2	ENSG00000109756	-1.0526546776254608	[157,148]	[28,17]	-8	dCas9-VP64	positive selection	2482926
159140880	159140903	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGTAGTGGCGCGATCTCAG	RAPGEF2	ENSG00000109756	0.8627698723325049	[50,145]	[36,76]	6	dCas9-VP64	positive selection	2487501
159281101	159281124	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTCGGGAGACTGAGGCAGG	RAPGEF2	ENSG00000109756	-1.0734520873599889	[20,56]	[6,3]	-8	dCas9-VP64	positive selection	2503853
159130951	159130974	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGGGCAG	RAPGEF2	ENSG00000109756	-0.3040415459965904	[20,19]	[5,3]	-3	dCas9-VP64	positive selection	2518508
159267666	159267689	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACAAGGGTATTAACAATGCTTGG	RAPGEF2	ENSG00000109756	0.5212100462928999	[86,124]	[43,53]	4	dCas9-VP64	positive selection	2538924
159267684	159267707	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTGGCTGAATGCTAGAGCCTGG	RAPGEF2	ENSG00000109756	0.4153073511137294	[56,51]	[26,19]	3	dCas9-VP64	positive selection	2538925
159267649	159267672	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGATTGCAGATGAAACAAGG	RAPGEF2	ENSG00000109756	1.230336474310849	[174,130]	[59,171]	7	dCas9-VP64	positive selection	2538926
159214986	159215009	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATACCAACTACTTGG	RAPGEF2	ENSG00000109756	0.7947980887601276	[215,263]	[62,203]	5	dCas9-VP64	positive selection	2543960
159130823	159130846	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGGAGGCTGTGG	RAPGEF2	ENSG00000109756	0.27268558780642654	[105,40]	[39,17]	2	dCas9-VP64	positive selection	2553443
159234967	159234990	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTAGGAGTTCGAGACCAGCCTAG	RAPGEF2	ENSG00000109756	2.6650986342381273	[238,153]	[58,738]	9	dCas9-VP64	positive selection	2556770
159131183	159131206	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCGCAACCTCCGCCTCCTAG	RAPGEF2	ENSG00000109756	0.25678800348412345	[582,649]	[296,187]	2	dCas9-VP64	positive selection	2564420
159131202	159131225	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCAGAATCGCTTGAACCTAG	RAPGEF2	ENSG00000109756	2.6681151119317885	[136,149]	[134,451]	9	dCas9-VP64	positive selection	2566118
159209123	159209146	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCTGCCTGAG	RAPGEF2	ENSG00000109756	0.2626572524246065	[103,174]	[69,39]	2	dCas9-VP64	positive selection	2570461
159343063	159343086	4	-	27260157	DLD1	viability	TGGAAGGATCAAACAGGTCTTGG	RAPGEF2	ENSG00000109756	0.702881498372168	[]	[]	8	hSpCas9	negative selection	2575008
159332535	159332558	4	-	27260157	DLD1	viability	ATCTGGAATGGAGTAGCGACTGG	RAPGEF2	ENSG00000109756	1.31436174572056	[]	[]	9	hSpCas9	negative selection	2575084
159331644	159331667	4	-	27260157	DLD1	viability	ACGCGATATTCAACAGCCTTAGG	RAPGEF2	ENSG00000109756	0.106343355416872	[]	[]	3	hSpCas9	negative selection	2582929
159343342	159343365	4	+	27260157	DLD1	viability	AATTCGTCACGTTGGCCGAATGG	RAPGEF2	ENSG00000109756	0.352278747243176	[]	[]	4	hSpCas9	negative selection	2583294
159339308	159339331	4	-	27260157	DLD1	viability	GCAAGTTTGGAAAGCTGATCTGG	RAPGEF2	ENSG00000109756	0.76217427336269	[]	[]	8	hSpCas9	negative selection	2585788
159342999	159343022	4	+	27260157	DLD1	viability	TGGCAAGACTGCGAACGACCTGG	RAPGEF2	ENSG00000109756	0.726162288593326	[]	[]	8	hSpCas9	negative selection	2587445
159330470	159330493	4	+	27260157	DLD1	viability	GGTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.085738004492424	[]	[]	0	hSpCas9	negative selection	2606555
159268162	159268185	4	-	27260157	DLD1	viability	TGGTTAGCTGGGATTGCTAGTGG	RAPGEF2	ENSG00000109756	-0.934766155191735	[]	[]	-6	hSpCas9	negative selection	2609305
159314688	159314711	4	+	27260157	DLD1	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.723387915757524	[]	[]	8	hSpCas9	negative selection	2612093
159268173	159268196	4	-	27260157	DLD1	viability	CCATAACTCCATGGTTAGCTGGG	RAPGEF2	ENSG00000109756	0.284917752705724	[]	[]	4	hSpCas9	negative selection	2614394
159338387	159338410	4	-	27260157	DLD1	viability	GATGATAAGGTTCCACTGACAGG	RAPGEF2	ENSG00000109756	-0.79934423372272	[]	[]	-6	hSpCas9	negative selection	2615226
159345314	159345337	4	-	27260157	DLD1	viability	AACTCACATGTGTTGGTTGCTGG	RAPGEF2	ENSG00000109756	-0.564445588749635	[]	[]	-4	hSpCas9	negative selection	2616734
159314740	159314763	4	-	27260157	DLD1	viability	CATCATCTGTCCGGTCAATTGGG	RAPGEF2	ENSG00000109756	0.0667738919707668	[]	[]	3	hSpCas9	negative selection	2619614
159339114	159339137	4	+	27260157	DLD1	viability	ACTTGCCAGATCAAGTGCTAAGG	RAPGEF2	ENSG00000109756	-0.175473458270066	[]	[]	-1	hSpCas9	negative selection	2620584
159329960	159329983	4	+	27260157	DLD1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.248416749256343	[]	[]	4	hSpCas9	negative selection	2621573
159329872	159329895	4	-	27260157	DLD1	viability	GAATACGGCAGTAATCTTGCTGG	RAPGEF2	ENSG00000109756	-0.976053026191916	[]	[]	-7	hSpCas9	negative selection	2641789
159314728	159314751	4	-	27260157	DLD1	viability	GGTCAATTGGGTCCTTCTCTAGG	RAPGEF2	ENSG00000109756	0.028602537962691	[]	[]	0	hSpCas9	negative selection	2643850
159314606	159314629	4	+	27260157	DLD1	viability	GCTGGTGATATGGACCTGAGTGG	RAPGEF2	ENSG00000109756	-0.249459131763045	[]	[]	-2	hSpCas9	negative selection	2644032
159345137	159345160	4	+	27260157	DLD1	viability	GTGCTAGATGTTGCTCAGACAGG	RAPGEF2	ENSG00000109756	-0.624140817008939	[]	[]	-5	hSpCas9	negative selection	2649074
159341887	159341910	4	+	27260157	DLD1	viability	TCAAGATAGCACTGCACTGTAGG	RAPGEF2	ENSG00000109756	0.422743732405529	[]	[]	7	hSpCas9	negative selection	2649387
159343063	159343086	4	-	27260157	HT1080	viability	TGGAAGGATCAAACAGGTCTTGG	RAPGEF2	ENSG00000109756	0.311822806603735	[]	[]	3	hSpCas9	negative selection	2651138
159332535	159332558	4	-	27260157	HT1080	viability	ATCTGGAATGGAGTAGCGACTGG	RAPGEF2	ENSG00000109756	1.38192341759381	[]	[]	9	hSpCas9	negative selection	2651214
159331644	159331667	4	-	27260157	HT1080	viability	ACGCGATATTCAACAGCCTTAGG	RAPGEF2	ENSG00000109756	1.60477404591164	[]	[]	9	hSpCas9	negative selection	2659059
159343342	159343365	4	+	27260157	HT1080	viability	AATTCGTCACGTTGGCCGAATGG	RAPGEF2	ENSG00000109756	1.2473827173706	[]	[]	8	hSpCas9	negative selection	2659424
159339308	159339331	4	-	27260157	HT1080	viability	GCAAGTTTGGAAAGCTGATCTGG	RAPGEF2	ENSG00000109756	0.695778443826077	[]	[]	6	hSpCas9	negative selection	2661918
159342999	159343022	4	+	27260157	HT1080	viability	TGGCAAGACTGCGAACGACCTGG	RAPGEF2	ENSG00000109756	0.377506160149358	[]	[]	3	hSpCas9	negative selection	2663575
159330470	159330493	4	+	27260157	HT1080	viability	GGTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.0695353135355716	[]	[]	0	hSpCas9	negative selection	2682685
159268162	159268185	4	-	27260157	HT1080	viability	TGGTTAGCTGGGATTGCTAGTGG	RAPGEF2	ENSG00000109756	-0.491285821737242	[]	[]	-7	hSpCas9	negative selection	2685435
159314688	159314711	4	+	27260157	HT1080	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.136125638507394	[]	[]	1	hSpCas9	negative selection	2688223
159268173	159268196	4	-	27260157	HT1080	viability	CCATAACTCCATGGTTAGCTGGG	RAPGEF2	ENSG00000109756	-0.288086816224539	[]	[]	-7	hSpCas9	negative selection	2690524
159338387	159338410	4	-	27260157	HT1080	viability	GATGATAAGGTTCCACTGACAGG	RAPGEF2	ENSG00000109756	0.154458068789706	[]	[]	1	hSpCas9	negative selection	2691356
159345314	159345337	4	-	27260157	HT1080	viability	AACTCACATGTGTTGGTTGCTGG	RAPGEF2	ENSG00000109756	-0.109552871624009	[]	[]	0	hSpCas9	negative selection	2692864
159314740	159314763	4	-	27260157	HT1080	viability	CATCATCTGTCCGGTCAATTGGG	RAPGEF2	ENSG00000109756	1.05997238330539	[]	[]	8	hSpCas9	negative selection	2695744
159339114	159339137	4	+	27260157	HT1080	viability	ACTTGCCAGATCAAGTGCTAAGG	RAPGEF2	ENSG00000109756	0.128081903267401	[]	[]	1	hSpCas9	negative selection	2696714
159329960	159329983	4	+	27260157	HT1080	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.125055911799435	[]	[]	0	hSpCas9	negative selection	2697703
159329872	159329895	4	-	27260157	HT1080	viability	GAATACGGCAGTAATCTTGCTGG	RAPGEF2	ENSG00000109756	0.341480363577528	[]	[]	3	hSpCas9	negative selection	2717919
159314728	159314751	4	-	27260157	HT1080	viability	GGTCAATTGGGTCCTTCTCTAGG	RAPGEF2	ENSG00000109756	-0.616495529462451	[]	[]	-8	hSpCas9	negative selection	2719980
159314606	159314629	4	+	27260157	HT1080	viability	GCTGGTGATATGGACCTGAGTGG	RAPGEF2	ENSG00000109756	-0.309322368078258	[]	[]	-7	hSpCas9	negative selection	2720162
159345137	159345160	4	+	27260157	HT1080	viability	GTGCTAGATGTTGCTCAGACAGG	RAPGEF2	ENSG00000109756	0.324301399233069	[]	[]	3	hSpCas9	negative selection	2725204
159341887	159341910	4	+	27260157	HT1080	viability	TCAAGATAGCACTGCACTGTAGG	RAPGEF2	ENSG00000109756	-0.888446984009843	[]	[]	-8	hSpCas9	negative selection	2725517
159343063	159343086	4	-	27260157	MKN45	viability	TGGAAGGATCAAACAGGTCTTGG	RAPGEF2	ENSG00000109756	1.28015552126878	[]	[]	9	hSpCas9	negative selection	2727268
159332535	159332558	4	-	27260157	MKN45	viability	ATCTGGAATGGAGTAGCGACTGG	RAPGEF2	ENSG00000109756	1.53212288838602	[]	[]	9	hSpCas9	negative selection	2727344
159331644	159331667	4	-	27260157	MKN45	viability	ACGCGATATTCAACAGCCTTAGG	RAPGEF2	ENSG00000109756	0.0307300403527902	[]	[]	0	hSpCas9	negative selection	2735189
159343342	159343365	4	+	27260157	MKN45	viability	AATTCGTCACGTTGGCCGAATGG	RAPGEF2	ENSG00000109756	0.51594323476587	[]	[]	6	hSpCas9	negative selection	2735554
159339308	159339331	4	-	27260157	MKN45	viability	GCAAGTTTGGAAAGCTGATCTGG	RAPGEF2	ENSG00000109756	0.315089462017784	[]	[]	5	hSpCas9	negative selection	2738048
159342999	159343022	4	+	27260157	MKN45	viability	TGGCAAGACTGCGAACGACCTGG	RAPGEF2	ENSG00000109756	1.20325298290965	[]	[]	9	hSpCas9	negative selection	2739705
159330470	159330493	4	+	27260157	MKN45	viability	GGTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	1.18298246486136	[]	[]	8	hSpCas9	negative selection	2758815
159268162	159268185	4	-	27260157	MKN45	viability	TGGTTAGCTGGGATTGCTAGTGG	RAPGEF2	ENSG00000109756	0.64974798842226	[]	[]	7	hSpCas9	negative selection	2761565
159314688	159314711	4	+	27260157	MKN45	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.669497444904544	[]	[]	7	hSpCas9	negative selection	2764353
159268173	159268196	4	-	27260157	MKN45	viability	CCATAACTCCATGGTTAGCTGGG	RAPGEF2	ENSG00000109756	0.120003906948357	[]	[]	4	hSpCas9	negative selection	2766654
159338387	159338410	4	-	27260157	MKN45	viability	GATGATAAGGTTCCACTGACAGG	RAPGEF2	ENSG00000109756	0.829726744151533	[]	[]	8	hSpCas9	negative selection	2767486
159345314	159345337	4	-	27260157	MKN45	viability	AACTCACATGTGTTGGTTGCTGG	RAPGEF2	ENSG00000109756	0.274488366511468	[]	[]	5	hSpCas9	negative selection	2768994
159314740	159314763	4	-	27260157	MKN45	viability	CATCATCTGTCCGGTCAATTGGG	RAPGEF2	ENSG00000109756	-0.00362380984411749	[]	[]	0	hSpCas9	negative selection	2771874
159339114	159339137	4	+	27260157	MKN45	viability	ACTTGCCAGATCAAGTGCTAAGG	RAPGEF2	ENSG00000109756	0.220204772843835	[]	[]	5	hSpCas9	negative selection	2772844
159329960	159329983	4	+	27260157	MKN45	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.60033661112476	[]	[]	7	hSpCas9	negative selection	2773833
159329872	159329895	4	-	27260157	MKN45	viability	GAATACGGCAGTAATCTTGCTGG	RAPGEF2	ENSG00000109756	-0.326362516752432	[]	[]	-1	hSpCas9	negative selection	2794049
159314728	159314751	4	-	27260157	MKN45	viability	GGTCAATTGGGTCCTTCTCTAGG	RAPGEF2	ENSG00000109756	0.243078317713958	[]	[]	5	hSpCas9	negative selection	2796110
159314606	159314629	4	+	27260157	MKN45	viability	GCTGGTGATATGGACCTGAGTGG	RAPGEF2	ENSG00000109756	0.0978135124726712	[]	[]	0	hSpCas9	negative selection	2796292
159345137	159345160	4	+	27260157	MKN45	viability	GTGCTAGATGTTGCTCAGACAGG	RAPGEF2	ENSG00000109756	1.98034251109132	[]	[]	9	hSpCas9	negative selection	2801334
159341887	159341910	4	+	27260157	MKN45	viability	TCAAGATAGCACTGCACTGTAGG	RAPGEF2	ENSG00000109756	0.689591743082522	[]	[]	7	hSpCas9	negative selection	2801647
159343063	159343086	4	-	27260157	RKO	viability	TGGAAGGATCAAACAGGTCTTGG	RAPGEF2	ENSG00000109756	0.0027876718404602	[]	[]	0	hSpCas9	negative selection	2803398
159332535	159332558	4	-	27260157	RKO	viability	ATCTGGAATGGAGTAGCGACTGG	RAPGEF2	ENSG00000109756	0.497872130493995	[]	[]	2	hSpCas9	negative selection	2803474
159331644	159331667	4	-	27260157	RKO	viability	ACGCGATATTCAACAGCCTTAGG	RAPGEF2	ENSG00000109756	0.43727560194196	[]	[]	2	hSpCas9	negative selection	2811319
159343342	159343365	4	+	27260157	RKO	viability	AATTCGTCACGTTGGCCGAATGG	RAPGEF2	ENSG00000109756	0.786375136079305	[]	[]	8	hSpCas9	negative selection	2811684
159339308	159339331	4	-	27260157	RKO	viability	GCAAGTTTGGAAAGCTGATCTGG	RAPGEF2	ENSG00000109756	0.894223723393918	[]	[]	8	hSpCas9	negative selection	2814178
159342999	159343022	4	+	27260157	RKO	viability	TGGCAAGACTGCGAACGACCTGG	RAPGEF2	ENSG00000109756	0.699716105497134	[]	[]	8	hSpCas9	negative selection	2815835
159330470	159330493	4	+	27260157	RKO	viability	GGTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.538547024808905	[]	[]	3	hSpCas9	negative selection	2834945
159268162	159268185	4	-	27260157	RKO	viability	TGGTTAGCTGGGATTGCTAGTGG	RAPGEF2	ENSG00000109756	0.266463305664981	[]	[]	1	hSpCas9	negative selection	2837695
159314688	159314711	4	+	27260157	RKO	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.00577272953724537	[]	[]	0	hSpCas9	negative selection	2840483
159268173	159268196	4	-	27260157	RKO	viability	CCATAACTCCATGGTTAGCTGGG	RAPGEF2	ENSG00000109756	-0.222955314808016	[]	[]	-1	hSpCas9	negative selection	2842784
159338387	159338410	4	-	27260157	RKO	viability	GATGATAAGGTTCCACTGACAGG	RAPGEF2	ENSG00000109756	-0.178695867537946	[]	[]	-1	hSpCas9	negative selection	2843616
159345314	159345337	4	-	27260157	RKO	viability	AACTCACATGTGTTGGTTGCTGG	RAPGEF2	ENSG00000109756	-0.616667438757857	[]	[]	-7	hSpCas9	negative selection	2845124
159314740	159314763	4	-	27260157	RKO	viability	CATCATCTGTCCGGTCAATTGGG	RAPGEF2	ENSG00000109756	1.22010347589317	[]	[]	9	hSpCas9	negative selection	2848004
159339114	159339137	4	+	27260157	RKO	viability	ACTTGCCAGATCAAGTGCTAAGG	RAPGEF2	ENSG00000109756	0.223307884313067	[]	[]	1	hSpCas9	negative selection	2848974
159329960	159329983	4	+	27260157	RKO	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.288042261521451	[]	[]	1	hSpCas9	negative selection	2849963
159329872	159329895	4	-	27260157	RKO	viability	GAATACGGCAGTAATCTTGCTGG	RAPGEF2	ENSG00000109756	-0.24072797348505	[]	[]	-1	hSpCas9	negative selection	2870179
159314728	159314751	4	-	27260157	RKO	viability	GGTCAATTGGGTCCTTCTCTAGG	RAPGEF2	ENSG00000109756	0.809150666823457	[]	[]	8	hSpCas9	negative selection	2872240
159314606	159314629	4	+	27260157	RKO	viability	GCTGGTGATATGGACCTGAGTGG	RAPGEF2	ENSG00000109756	-0.189775330116718	[]	[]	-1	hSpCas9	negative selection	2872422
159345137	159345160	4	+	27260157	RKO	viability	GTGCTAGATGTTGCTCAGACAGG	RAPGEF2	ENSG00000109756	0.0703543877546117	[]	[]	0	hSpCas9	negative selection	2877464
159341887	159341910	4	+	27260157	RKO	viability	TCAAGATAGCACTGCACTGTAGG	RAPGEF2	ENSG00000109756	-0.204800284634333	[]	[]	-1	hSpCas9	negative selection	2877777
159343063	159343086	4	-	27260157	SF268	viability	TGGAAGGATCAAACAGGTCTTGG	RAPGEF2	ENSG00000109756	0.0452531295057298	[]	[]	0	hSpCas9	negative selection	2879528
159332535	159332558	4	-	27260157	SF268	viability	ATCTGGAATGGAGTAGCGACTGG	RAPGEF2	ENSG00000109756	0.655553274147363	[]	[]	8	hSpCas9	negative selection	2879604
159331644	159331667	4	-	27260157	SF268	viability	ACGCGATATTCAACAGCCTTAGG	RAPGEF2	ENSG00000109756	0.619940013108081	[]	[]	8	hSpCas9	negative selection	2887449
159343342	159343365	4	+	27260157	SF268	viability	AATTCGTCACGTTGGCCGAATGG	RAPGEF2	ENSG00000109756	1.20582585982261	[]	[]	9	hSpCas9	negative selection	2887814
159339308	159339331	4	-	27260157	SF268	viability	GCAAGTTTGGAAAGCTGATCTGG	RAPGEF2	ENSG00000109756	1.20023402777886	[]	[]	9	hSpCas9	negative selection	2890308
159342999	159343022	4	+	27260157	SF268	viability	TGGCAAGACTGCGAACGACCTGG	RAPGEF2	ENSG00000109756	0.14787577912519	[]	[]	0	hSpCas9	negative selection	2891965
159330470	159330493	4	+	27260157	SF268	viability	GGTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.613968643512056	[]	[]	8	hSpCas9	negative selection	2911075
159268162	159268185	4	-	27260157	SF268	viability	TGGTTAGCTGGGATTGCTAGTGG	RAPGEF2	ENSG00000109756	0.407386692204859	[]	[]	4	hSpCas9	negative selection	2913825
159314688	159314711	4	+	27260157	SF268	viability	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.20704553620398	[]	[]	-2	hSpCas9	negative selection	2916613
159268173	159268196	4	-	27260157	SF268	viability	CCATAACTCCATGGTTAGCTGGG	RAPGEF2	ENSG00000109756	-0.120676093822488	[]	[]	-1	hSpCas9	negative selection	2918914
159338387	159338410	4	-	27260157	SF268	viability	GATGATAAGGTTCCACTGACAGG	RAPGEF2	ENSG00000109756	0.542440440962363	[]	[]	8	hSpCas9	negative selection	2919746
159345314	159345337	4	-	27260157	SF268	viability	AACTCACATGTGTTGGTTGCTGG	RAPGEF2	ENSG00000109756	-0.649158188627397	[]	[]	-5	hSpCas9	negative selection	2921254
159314740	159314763	4	-	27260157	SF268	viability	CATCATCTGTCCGGTCAATTGGG	RAPGEF2	ENSG00000109756	1.23865557835837	[]	[]	9	hSpCas9	negative selection	2924134
159339114	159339137	4	+	27260157	SF268	viability	ACTTGCCAGATCAAGTGCTAAGG	RAPGEF2	ENSG00000109756	0.473018251587443	[]	[]	7	hSpCas9	negative selection	2925104
159329960	159329983	4	+	27260157	SF268	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.184439699074804	[]	[]	-1	hSpCas9	negative selection	2926093
159329872	159329895	4	-	27260157	SF268	viability	GAATACGGCAGTAATCTTGCTGG	RAPGEF2	ENSG00000109756	-1.40980109972941	[]	[]	-8	hSpCas9	negative selection	2946309
159314728	159314751	4	-	27260157	SF268	viability	GGTCAATTGGGTCCTTCTCTAGG	RAPGEF2	ENSG00000109756	-0.742761208464647	[]	[]	-5	hSpCas9	negative selection	2948370
159314606	159314629	4	+	27260157	SF268	viability	GCTGGTGATATGGACCTGAGTGG	RAPGEF2	ENSG00000109756	0.00655768734483571	[]	[]	0	hSpCas9	negative selection	2948552
159345137	159345160	4	+	27260157	SF268	viability	GTGCTAGATGTTGCTCAGACAGG	RAPGEF2	ENSG00000109756	0.123710542643385	[]	[]	0	hSpCas9	negative selection	2953594
159341887	159341910	4	+	27260157	SF268	viability	TCAAGATAGCACTGCACTGTAGG	RAPGEF2	ENSG00000109756	0.181857568148108	[]	[]	0	hSpCas9	negative selection	2953907
159339240	159339263	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	0.10089633681223592	[4,4]	[4,4]	2	hSpCas9	positive selection	3015666
159268166	159268189	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	0.4674349777368568	[4,4]	[4,5]	8	hSpCas9	positive selection	3015667
159339330	159339353	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	0.3319258227978076	[3,3]	[2,4]	7	hSpCas9	positive selection	3015668
159341565	159341588	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	0.3340921549308832	[4,4]	[4,5]	7	hSpCas9	positive selection	3015669
159339240	159339263	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	-0.0384977664014271	[4,4]	[4,2]	0	hSpCas9	positive selection	3083524
159268166	159268189	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-0.5149543987156677	[4,4]	[3,0]	-7	hSpCas9	positive selection	3083525
159339330	159339353	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	0.20275402252931404	[3,3]	[4,1]	3	hSpCas9	positive selection	3083526
159341565	159341588	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	0.19597132409428084	[4,4]	[3,3]	3	hSpCas9	positive selection	3083527
159322386	159322409		+	24336571	A375	resistance to PLX after 7 days	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	0.1764321609711191	[12,8]	[11,13]	5	hSpCas9	positive selection	3139761
159322386	159322409		-	24336571	A375	resistance to PLX after 7 days	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	-0.16008067754596467	[6,9]	[7,6]	-5	hSpCas9	positive selection	3139762
159304413	159304436		-	24336571	A375	resistance to PLX after 7 days	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.15187228964703625	[8,8]	[7,7]	-5	hSpCas9	positive selection	3139763
159304423	159304446		+	24336571	A375	resistance to PLX after 7 days	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	-0.11782243277644544	[24,18]	[19,20]	-4	hSpCas9	positive selection	3139764
159322386	159322409		+	24336571	A375	resistance to PLX after 14 days	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	-0.5759744310396543	[13,10]	[3,3]	-6	hSpCas9	positive selection	3197554
159322386	159322409		-	24336571	A375	resistance to PLX after 14 days	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	-0.43538461795317457	[10,7]	[2,2]	-5	hSpCas9	positive selection	3197555
159304413	159304436		-	24336571	A375	resistance to PLX after 14 days	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.9922616933190656	[7,9]	[8,6]	7	hSpCas9	positive selection	3197556
159304423	159304446		+	24336571	A375	resistance to PLX after 14 days	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	-0.6726421557669088	[25,20]	[6,5]	-7	hSpCas9	positive selection	3197557
159322386	159322409		+	24336571	A375	viability after 7 days	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	-0.18519803830683754	[13]	[12,8]	-3	hSpCas9	negative selection	3255347
159322386	159322409		-	24336571	A375	viability after 7 days	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.7415540924205546	[4]	[6,9]	9	hSpCas9	negative selection	3255348
159304413	159304436		-	24336571	A375	viability after 7 days	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.11885942903266333	[9]	[8,8]	-2	hSpCas9	negative selection	3255349
159304423	159304446		+	24336571	A375	viability after 7 days	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	0.7647024769273458	[12]	[24,18]	9	hSpCas9	negative selection	3255350
159322386	159322409		+	24336571	A375	viability after 14 days	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	-0.0147953275394347	[13]	[13,10]	0	hSpCas9	negative selection	3313140
159322386	159322409		-	24336571	A375	viability after 14 days	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.8991462094768103	[4]	[10,7]	9	hSpCas9	negative selection	3313141
159304413	159304436		-	24336571	A375	viability after 14 days	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.15496313871085954	[9]	[7,9]	-2	hSpCas9	negative selection	3313142
159304423	159304446		+	24336571	A375	viability after 14 days	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	0.8685454243669196	[12]	[25,20]	9	hSpCas9	negative selection	3313143
159304399	159304422	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3388988
159322386	159322409	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	-0.6191907351191646	[234,234]	[0,0]	-4	hSpCas9	positive selection	3388989
159329962	159329985	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3388990
159339240	159339263	4	-	26780180	HT29	viability (Avana library 4 designs)	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	1.29062614724017	[]	[]	5	hSpCas9	negative selection	3453930
159268165	159268188	4	+	26780180	HT29	viability (Avana library 4 designs)	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-0.325859478168029	[]	[]	-5	hSpCas9	negative selection	3453931
159339329	159339352	4	+	26780180	HT29	viability (Avana library 4 designs)	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	0.393627439908016	[]	[]	1	hSpCas9	negative selection	3453932
159341564	159341587	4	+	26780180	HT29	viability (Avana library 4 designs)	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	-0.402146440521814	[]	[]	-6	hSpCas9	negative selection	3453933
159268165	159268188	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-2.6777656161143	[]	[]	-3	hSpCas9	negative selection	3551032
159339329	159339352	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	-6.32435296445427	[]	[]	-6	hSpCas9	negative selection	3551033
159339240	159339263	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	-12.4205525122525	[]	[]	-8	hSpCas9	negative selection	3551034
159341564	159341587	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	-28.9610216317992	[]	[]	-9	hSpCas9	negative selection	3551035
159332564	159332587	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATGTAGAACAGGTGATAGG	RAPGEF2	ENSG00000109756	-2.39233198838476	[]	[]	-3	hSpCas9	negative selection	3551036
159341647	159341670	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACAGTGCTGAGCTGAAGGAGGG	RAPGEF2	ENSG00000109756	-0.956045224435928	[]	[]	-1	hSpCas9	negative selection	3551037
159268165	159268188	4	+	26780180	A375	viability (Avana lentiGuide)	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-2.29051885324418	[]	[]	-4	hSpCas9	negative selection	3659691
159339329	159339352	4	+	26780180	A375	viability (Avana lentiGuide)	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	-4.53019204621742	[]	[]	-7	hSpCas9	negative selection	3659692
159339240	159339263	4	-	26780180	A375	viability (Avana lentiGuide)	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	6.66188826536135	[]	[]	5	hSpCas9	negative selection	3659693
159341564	159341587	4	+	26780180	A375	viability (Avana lentiGuide)	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	3.74356350583701	[]	[]	3	hSpCas9	negative selection	3659694
159332564	159332587	4	+	26780180	A375	viability (Avana lentiGuide)	GTAGATGTAGAACAGGTGATAGG	RAPGEF2	ENSG00000109756	3.2306471390217	[]	[]	3	hSpCas9	negative selection	3659695
159341647	159341670	4	-	26780180	A375	viability (Avana lentiGuide)	CACAGTGCTGAGCTGAAGGAGGG	RAPGEF2	ENSG00000109756	11.9762115135903	[]	[]	7	hSpCas9	negative selection	3659696
159268165	159268188	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-0.5129282296453935	[5]	[4,2]	-6	hSpCas9	positive selection	3768298
159339329	159339352	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	-0.5695223973099586	[4]	[3,2]	-7	hSpCas9	positive selection	3768299
159339240	159339263	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	-0.585950628370684	[8]	[6,4]	-7	hSpCas9	positive selection	3768300
159341564	159341587	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	-1.12772396752678	[8]	[3,2]	-9	hSpCas9	positive selection	3768301
159332564	159332587	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATGTAGAACAGGTGATAGG	RAPGEF2	ENSG00000109756	-0.1192475077786697	[5]	[6,3]	-2	hSpCas9	positive selection	3768302
159341647	159341670	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACAGTGCTGAGCTGAAGGAGGG	RAPGEF2	ENSG00000109756	0.29738891722036714	[4]	[5,5]	8	hSpCas9	positive selection	3768303
159268165	159268188	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGCAATCCCAGCTAACCATGG	RAPGEF2	ENSG00000109756	-0.0016846481826918226	[5]	[3,5]	0	hSpCas9	positive selection	3876905
159339329	159339352	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGACAGAATACAACTGAGTGG	RAPGEF2	ENSG00000109756	0.0053466142268011885	[4]	[5,2]	0	hSpCas9	positive selection	3876906
159339240	159339263	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATAGTGAATATTGATCCGGGG	RAPGEF2	ENSG00000109756	-0.03256025392182235	[6]	[4,5]	0	hSpCas9	positive selection	3876907
159341564	159341587	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATTATCTGAAAAACAACATGG	RAPGEF2	ENSG00000109756	0.3563839344744602	[5]	[5,6]	9	hSpCas9	positive selection	3876908
159332564	159332587	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATGTAGAACAGGTGATAGG	RAPGEF2	ENSG00000109756	0.3094855881031424	[5]	[6,5]	8	hSpCas9	positive selection	3876909
159341647	159341670	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACAGTGCTGAGCTGAAGGAGGG	RAPGEF2	ENSG00000109756	-0.05237169909971873	[4]	[5,2]	0	hSpCas9	positive selection	3876910
159329960	159329983	4	+	26780180	A375	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.488470062360557	[]	[]	1	hSpCas9	negative selection	3987320
159304399	159304422	4	+	26780180	A375	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	1.20774340429275	[]	[]	6	hSpCas9	negative selection	3987321
159322386	159322409	4	-	26780180	A375	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	1.16818881903982	[]	[]	6	hSpCas9	negative selection	3987322
159322454	159322477	4	+	26780180	A375	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.530626801665207	[]	[]	1	hSpCas9	negative selection	3987323
159304413	159304436	4	-	26780180	A375	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	1.1469569616774	[]	[]	6	hSpCas9	negative selection	3987324
159329962	159329985	4	-	26780180	A375	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.635143826336478	[]	[]	2	hSpCas9	negative selection	3987325
159329960	159329983	4	+	26780180	HT29	viability (GeCKOv2 library)	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.755004933394295	[]	[]	3	hSpCas9	negative selection	4095286
159304399	159304422	4	+	26780180	HT29	viability (GeCKOv2 library)	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.82986888760316	[]	[]	3	hSpCas9	negative selection	4095287
159322386	159322409	4	-	26780180	HT29	viability (GeCKOv2 library)	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.243125082935569	[]	[]	0	hSpCas9	negative selection	4095288
159322454	159322477	4	+	26780180	HT29	viability (GeCKOv2 library)	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.371881755027382	[]	[]	1	hSpCas9	negative selection	4095289
159304413	159304436	4	-	26780180	HT29	viability (GeCKOv2 library)	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.720806584952749	[]	[]	2	hSpCas9	negative selection	4095290
159329962	159329985	4	-	26780180	HT29	viability (GeCKOv2 library)	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.175382872029591	[]	[]	0	hSpCas9	negative selection	4095291
159322386	159322409	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	-0.14038507104973136	[3]	[2,1]	-3	hSpCas9	positive selection	4165119
159322386	159322409	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.006267288150340555	[4]	[4,1]	0	hSpCas9	positive selection	4165120
159304413	159304436	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.3766872618776416	[2]	[1,2]	8	hSpCas9	positive selection	4165121
159304423	159304446	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	0.21010340426466872	[4]	[3,2]	5	hSpCas9	positive selection	4165122
159322386	159322409	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAATATGACAATGTCAGTGAGG	RAPGEF2	ENSG00000109756	-0.05835305543339965	[3]	[0,3,1,0]	-1	hSpCas9	positive selection	4229141
159322386	159322409	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3345838288899279	[4]	[5,2,4,0]	2	hSpCas9	positive selection	4229142
159304413	159304436	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	1.1876068084996196	[3]	[1,3,0,4]	8	hSpCas9	positive selection	4229143
159304423	159304446	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAGTATCACTAGTGATTCTGG	RAPGEF2	ENSG00000109756	0.04162522041851194	[3]	[1,4,0,0]	0	hSpCas9	positive selection	4229144
159329960	159329983	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.15066343639655078	[1]	[1,0]	-3	hSpCas9	positive selection	4293879
159322454	159322477	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.5236798486890106	[0]	[0,0]	-8	hSpCas9	positive selection	4293880
159304413	159304436	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.12536341557550734	[3]	[2,1]	-2	hSpCas9	positive selection	4293881
159304399	159304422	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.2721505528481515	[2]	[3,1]	5	hSpCas9	positive selection	4358137
159322386	159322409	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.41358706896192093	[3]	[3,3]	8	hSpCas9	positive selection	4358138
159329962	159329985	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.4675185579563796	[2]	[3,2]	8	hSpCas9	positive selection	4358139
159339161	159339183	4	+	27760321	OCIAML3	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	-0.29392312218290517	[262,207]	[137,163]	-3	hSpCas9	negative selection	4433151
159339237	159339259	4	-	27760321	OCIAML3	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.9058383365208711	[372,319]	[161,120]	-7	hSpCas9	negative selection	4433152
159329961	159329983	4	+	27760321	OCIAML3	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.33598378355749303	[439,344]	[370,402]	4	hSpCas9	negative selection	4433153
159330471	159330493	4	+	27760321	OCIAML3	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.1581184074769396	[492,472]	[419,424]	1	hSpCas9	negative selection	4433154
159331813	159331835	4	+	27760321	OCIAML3	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	-0.020890767176397873	[654,557]	[399,551]	0	hSpCas9	negative selection	4433155
159339161	159339183	4	+	27760321	OCIAML2	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.38743770095609487	[262,207]	[238,258]	5	hSpCas9	negative selection	4516614
159339237	159339259	4	-	27760321	OCIAML2	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.46541832152040663	[372,319]	[163,252]	-5	hSpCas9	negative selection	4516615
159329961	159329983	4	+	27760321	OCIAML2	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.2168870503922426	[439,344]	[303,448]	3	hSpCas9	negative selection	4516616
159330471	159330493	4	+	27760321	OCIAML2	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.4894434508799844	[492,472]	[488,628]	6	hSpCas9	negative selection	4516617
159331813	159331835	4	+	27760321	OCIAML2	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.40949500452810045	[654,557]	[633,669]	5	hSpCas9	negative selection	4516618
159339161	159339183	4	+	27760321	MV411	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	2.1838436083176687	[262,207]	[1014,230]	9	hSpCas9	negative selection	4600077
159339237	159339259	4	-	27760321	MV411	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.20327956653003	[372,319]	[100,504]	1	hSpCas9	negative selection	4600078
159329961	159329983	4	+	27760321	MV411	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.4927338506523441	[439,344]	[401,301]	3	hSpCas9	negative selection	4600079
159330471	159330493	4	+	27760321	MV411	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.20915453045742805	[492,472]	[220,358]	-1	hSpCas9	negative selection	4600080
159331813	159331835	4	+	27760321	MV411	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.6466528706329568	[654,557]	[524,773]	5	hSpCas9	negative selection	4600081
159339161	159339183	4	+	27760321	HL60	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.29595994390922187	[262,207]	[240,227]	3	hSpCas9	negative selection	4683540
159339237	159339259	4	-	27760321	HL60	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.5027505591455735	[372,319]	[394,404]	6	hSpCas9	negative selection	4683541
159329961	159329983	4	+	27760321	HL60	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.40571081165828193	[439,344]	[187,295]	-4	hSpCas9	negative selection	4683542
159330471	159330493	4	+	27760321	HL60	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.27168016467063305	[492,472]	[445,509]	3	hSpCas9	negative selection	4683543
159331813	159331835	4	+	27760321	HL60	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.7162191072287951	[654,557]	[670,959]	7	hSpCas9	negative selection	4683544
159339161	159339183	4	+	27760321	HT1080	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.9180452877291382	[207,162]	[79,204]	5	hSpCas9	negative selection	4767003
159339237	159339259	4	-	27760321	HT1080	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.22565691216560613	[319,249]	[169,91]	1	hSpCas9	negative selection	4767004
159329961	159329983	4	+	27760321	HT1080	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-2.626915363823677	[344,268]	[4,35]	-7	hSpCas9	negative selection	4767005
159330471	159330493	4	+	27760321	HT1080	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-1.4764935484694521	[472,368]	[86,30]	-5	hSpCas9	negative selection	4767006
159331813	159331835	4	+	27760321	HT1080	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	-1.9801127717318905	[557,435]	[11,91]	-6	hSpCas9	negative selection	4767007
159339161	159339183	4	+	27760321	HT29	viability after 7 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.7589597938785348	[207,162]	[444,385,385]	9	hSpCas9	negative selection	4850466
159339237	159339259	4	-	27760321	HT29	viability after 7 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.21396417182425387	[319,249]	[368,303,282]	-3	hSpCas9	negative selection	4850467
159329961	159329983	4	+	27760321	HT29	viability after 7 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.01255709088419113	[344,268]	[225,630,314]	0	hSpCas9	negative selection	4850468
159330471	159330493	4	+	27760321	HT29	viability after 7 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.32596166572553464	[472,368]	[325,403,545]	-5	hSpCas9	negative selection	4850469
159331813	159331835	4	+	27760321	HT29	viability after 7 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.34620095369401815	[557,435]	[981,662,814]	5	hSpCas9	negative selection	4850470
159339161	159339183	4	+	27760321	HT29	viability after 25 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.3388379275990594	[207,162]	[248,273,283]	3	hSpCas9	negative selection	4933929
159339237	159339259	4	-	27760321	HT29	viability after 25 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.17810150281900894	[319,249]	[322,284,248]	-2	hSpCas9	negative selection	4933930
159329961	159329983	4	+	27760321	HT29	viability after 25 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.30453704526397707	[344,268]	[420,315,577]	3	hSpCas9	negative selection	4933931
159330471	159330493	4	+	27760321	HT29	viability after 25 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.07126348179831618	[472,368]	[484,336,559]	0	hSpCas9	negative selection	4933932
159331813	159331835	4	+	27760321	HT29	viability after 25 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.4480771232877233	[557,435]	[585,831,933]	5	hSpCas9	negative selection	4933933
159339161	159339183	4	+	27760321	HT29	viability after 22 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.26277031394270023	[207,162]	[224,282,264]	2	hSpCas9	negative selection	5017392
159339237	159339259	4	-	27760321	HT29	viability after 22 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.15979645771589168	[319,249]	[408,255,215]	-2	hSpCas9	negative selection	5017393
159329961	159329983	4	+	27760321	HT29	viability after 22 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.20051809657115136	[344,268]	[416,308,497]	2	hSpCas9	negative selection	5017394
159330471	159330493	4	+	27760321	HT29	viability after 22 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.23094234426956423	[472,368]	[768,487,449]	2	hSpCas9	negative selection	5017395
159331813	159331835	4	+	27760321	HT29	viability after 22 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.4772545089805825	[557,435]	[830,642,925]	5	hSpCas9	negative selection	5017396
159339161	159339183	4	+	27760321	HT29	viability after 19 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.29978311187042217	[207,162]	[276,323,186]	3	hSpCas9	negative selection	5100855
159339237	159339259	4	-	27760321	HT29	viability after 19 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	-0.45451510409570783	[319,249]	[379,261,91]	-4	hSpCas9	negative selection	5100856
159329961	159329983	4	+	27760321	HT29	viability after 19 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.09535731779761983	[344,268]	[354,319,313]	-1	hSpCas9	negative selection	5100857
159330471	159330493	4	+	27760321	HT29	viability after 19 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.057811103434995736	[472,368]	[781,234,514]	0	hSpCas9	negative selection	5100858
159331813	159331835	4	+	27760321	HT29	viability after 19 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.6103203698388153	[557,435]	[818,999,781]	6	hSpCas9	negative selection	5100859
159339161	159339183	4	+	27760321	HT29	viability after 16 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.5964840046985898	[207,162]	[384,325,236]	7	hSpCas9	negative selection	5184318
159339237	159339259	4	-	27760321	HT29	viability after 16 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.30442400237371625	[319,249]	[391,360,428]	3	hSpCas9	negative selection	5184319
159329961	159329983	4	+	27760321	HT29	viability after 16 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.2695807696337119	[344,268]	[698,218,355]	3	hSpCas9	negative selection	5184320
159330471	159330493	4	+	27760321	HT29	viability after 16 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.038035525132018744	[472,368]	[591,372,425]	0	hSpCas9	negative selection	5184321
159331813	159331835	4	+	27760321	HT29	viability after 16 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.2603265985048888	[557,435]	[897,472,653]	3	hSpCas9	negative selection	5184322
159339161	159339183	4	+	27760321	HT29	viability after 13 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.3440679226902217	[207,162]	[309,226,281]	4	hSpCas9	negative selection	5267781
159339237	159339259	4	-	27760321	HT29	viability after 13 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.03068570914048352	[319,249]	[444,281,288]	0	hSpCas9	negative selection	5267782
159329961	159329983	4	+	27760321	HT29	viability after 13 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.0013737355692493014	[344,268]	[409,281,375]	0	hSpCas9	negative selection	5267783
159330471	159330493	4	+	27760321	HT29	viability after 13 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-0.2068644312386809	[472,368]	[322,478,464]	-2	hSpCas9	negative selection	5267784
159331813	159331835	4	+	27760321	HT29	viability after 13 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.25364405074088936	[557,435]	[453,754,843]	3	hSpCas9	negative selection	5267785
159339161	159339183	4	+	27760321	HT29	viability after 10 days	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	0.4850345045321724	[207,162]	[313,194,456]	6	hSpCas9	negative selection	5351244
159339237	159339259	4	-	27760321	HT29	viability after 10 days	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	0.12114060438934585	[319,249]	[302,423,433]	1	hSpCas9	negative selection	5351245
159329961	159329983	4	+	27760321	HT29	viability after 10 days	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.007731039893844688	[344,268]	[527,221,400]	0	hSpCas9	negative selection	5351246
159330471	159330493	4	+	27760321	HT29	viability after 10 days	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	0.09906228161215114	[472,368]	[505,550,629]	1	hSpCas9	negative selection	5351247
159331813	159331835	4	+	27760321	HT29	viability after 10 days	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.5879773370484329	[557,435]	[817,1178,810]	7	hSpCas9	negative selection	5351248
159339161	159339183	4	+	27760321	MOLM13	viability	CGCTACATCATGATCAGTAAGG	RAPGEF2	ENSG00000109756	1.4336396432561629	[262,207]	[320,386]	8	hSpCas9	negative selection	5434707
159339237	159339259	4	-	27760321	MOLM13	viability	AGTGAATATTGATCCGGGGTGG	RAPGEF2	ENSG00000109756	1.0366552829616225	[372,319]	[374,420]	7	hSpCas9	negative selection	5434708
159329961	159329983	4	+	27760321	MOLM13	viability	ACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.8742002431656907	[439,344]	[92,142]	-5	hSpCas9	negative selection	5434709
159330471	159330493	4	+	27760321	MOLM13	viability	GTTTAATGACCCGAGCCTCAGG	RAPGEF2	ENSG00000109756	-1.2866777816947634	[492,472]	[126,98]	-6	hSpCas9	negative selection	5434710
159331813	159331835	4	+	27760321	MOLM13	viability	GGCTTGAAACGGGGGGATCAGG	RAPGEF2	ENSG00000109756	0.8506014005342015	[654,557]	[412,786]	6	hSpCas9	negative selection	5434711
159267864	159267887	4	+	27661255	K562	viability	GGAAGACTGAGAGCTGTGTGAGG	RAPGEF2	ENSG00000109756	0.08282840684274381	[677,752]	[655,559]	3	dCas9-KRAB	negative selection	5506194
159268322	159268345	4	+	27661255	K562	viability	GTATAGTAGTCTGCTTGGAGAGG	RAPGEF2	ENSG00000109756	0.05887882436837644	[1618,1759]	[1664,1180]	2	dCas9-KRAB	negative selection	5506195
159268327	159268350	4	+	27661255	K562	viability	GTAGTCTGCTTGGAGAGGAGGGG	RAPGEF2	ENSG00000109756	0.08986358700524222	[1454,1630]	[1456,1182]	3	dCas9-KRAB	negative selection	5506196
159267702	159267725	4	-	27661255	K562	viability	GTCAGGGTGGTATAAGAACCAGG	RAPGEF2	ENSG00000109756	0.13274322205896139	[1171,1360]	[1177,1044]	4	dCas9-KRAB	negative selection	5506197
159268005	159268028	4	-	27661255	K562	viability	GCAGCTTAAAGTGTCACTACTGG	RAPGEF2	ENSG00000109756	-0.1574684392438469	[497,366]	[345,281]	-5	dCas9-KRAB	negative selection	5506198
159329960	159329983	4	+	27260156	BXPC3	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.19247371766915666	[124]	[84,168,55,149]	-4	hSpCas9	negative selection	5566339
159322454	159322477	4	+	27260156	BXPC3	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.5378679897920549	[54]	[76,56,112,89]	9	hSpCas9	negative selection	5566340
159304413	159304436	4	-	27260156	BXPC3	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.19042555685859752	[506]	[400,352,446,695]	-4	hSpCas9	negative selection	5566341
159304399	159304422	4	+	27260156	BXPC3	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.26316461074169506	[309]	[276,467,397,421]	6	hSpCas9	negative selection	5630597
159322386	159322409	4	-	27260156	BXPC3	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.15381820427914622	[482]	[430,477,646,728]	3	hSpCas9	negative selection	5630598
159329962	159329985	4	-	27260156	BXPC3	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.19834682368683942	[356]	[335,366,536,493]	4	hSpCas9	negative selection	5630599
159329960	159329983	4	+	27260156	A673	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.3657316106907289	[124]	[173,81,120,94]	-7	hSpCas9	negative selection	5687590
159322454	159322477	4	+	27260156	A673	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.291032592563059	[54]	[69,51,38,56]	-6	hSpCas9	negative selection	5687591
159304413	159304436	4	-	27260156	A673	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.3211658618204567	[506]	[626,475,324,540]	-7	hSpCas9	negative selection	5687592
159304399	159304422	4	+	27260156	A673	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.4102661626674051	[309]	[597,493,482,409]	8	hSpCas9	negative selection	5751848
159322386	159322409	4	-	27260156	A673	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3784134907222969	[482]	[889,676,654,813]	8	hSpCas9	negative selection	5751849
159329962	159329985	4	-	27260156	A673	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.24769395407864692	[356]	[589,425,494,536]	6	hSpCas9	negative selection	5751850
159329960	159329983	4	+	27260156	A375	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.12907862990590946	[124]	[126,69,132,187]	-2	hSpCas9	negative selection	5808841
159322454	159322477	4	+	27260156	A375	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-1.3143964812344056	[54]	[31,37,27,8]	-9	hSpCas9	negative selection	5808842
159304413	159304436	4	-	27260156	A375	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.4583750068455985	[506]	[494,429,508,303]	-6	hSpCas9	negative selection	5808843
159304399	159304422	4	+	27260156	A375	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.5423315132116728	[309]	[581,650,449,450]	7	hSpCas9	negative selection	5873099
159322386	159322409	4	-	27260156	A375	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.6101640985284151	[482]	[721,915,673,1105]	8	hSpCas9	negative selection	5873100
159329962	159329985	4	-	27260156	A375	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.28342880383643193	[356]	[428,479,573,536]	4	hSpCas9	negative selection	5873101
159329960	159329983	4	+	27260156	COLO741	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.3420641000580025	[124]	[85,100,182]	-6	hSpCas9	negative selection	5930092
159322454	159322477	4	+	27260156	COLO741	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.2558379508464026	[54]	[70,88,89]	5	hSpCas9	negative selection	5930093
159304413	159304436	4	-	27260156	COLO741	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.20430164866035505	[506]	[498,614,565]	-4	hSpCas9	negative selection	5930094
159304399	159304422	4	+	27260156	COLO741	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.1721006788495309	[309]	[423,479,432]	3	hSpCas9	negative selection	5994350
159322386	159322409	4	-	27260156	COLO741	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.11698522057088565	[482]	[737,660,616]	2	hSpCas9	negative selection	5994351
159329962	159329985	4	-	27260156	COLO741	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.2346921739758236	[356]	[643,536,443]	5	hSpCas9	negative selection	5994352
159329960	159329983	4	+	27260156	CAL120	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.5640587109067554	[124]	[260,232,200]	8	hSpCas9	negative selection	6051343
159322454	159322477	4	+	27260156	CAL120	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.6669387192375553	[54]	[27,19,262]	8	hSpCas9	negative selection	6051344
159304413	159304436	4	-	27260156	CAL120	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.10775074505028234	[506]	[750,323,703]	-1	hSpCas9	negative selection	6051345
159304399	159304422	4	+	27260156	CAL120	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	-0.2574919871060417	[309]	[383,426,168]	-4	hSpCas9	negative selection	6115601
159322386	159322409	4	-	27260156	CAL120	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.6602784972185163	[482]	[986,1095,774]	8	hSpCas9	negative selection	6115602
159329962	159329985	4	-	27260156	CAL120	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.5557737962094982	[356]	[714,760,494]	8	hSpCas9	negative selection	6115603
159329960	159329983	4	+	27260156	CADOES1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.3581783817971167	[124]	[156,255,92,87]	6	hSpCas9	negative selection	6172594
159322454	159322477	4	+	27260156	CADOES1	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.3473042496311529	[54]	[34,68,39,15]	-6	hSpCas9	negative selection	6172595
159304413	159304436	4	-	27260156	CADOES1	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.0954274773072799	[506]	[473,681,396,460]	1	hSpCas9	negative selection	6172596
159304399	159304422	4	+	27260156	CADOES1	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.7739659033287443	[309]	[286,563,518,606]	9	hSpCas9	negative selection	6236852
159322386	159322409	4	-	27260156	CADOES1	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3687366900923176	[482]	[770,622,442,478]	6	hSpCas9	negative selection	6236853
159329962	159329985	4	-	27260156	CADOES1	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.3037733975179625	[356]	[324,461,409,443]	5	hSpCas9	negative selection	6236854
159329960	159329983	4	+	27260156	EWS502	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.474698694158894	[124]	[89,134,78,73]	-7	hSpCas9	negative selection	6293845
159322454	159322477	4	+	27260156	EWS502	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.4477993731215357	[54]	[17,57,73,21]	-6	hSpCas9	negative selection	6293846
159304413	159304436	4	-	27260156	EWS502	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.24066834000948722	[506]	[531,438,499,327]	-4	hSpCas9	negative selection	6293847
159304399	159304422	4	+	27260156	EWS502	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.38403232888780836	[309]	[361,560,378,410]	6	hSpCas9	negative selection	6358103
159322386	159322409	4	-	27260156	EWS502	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.5868860033760919	[482]	[802,589,748,943]	8	hSpCas9	negative selection	6358104
159329962	159329985	4	-	27260156	EWS502	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.4412650750743689	[356]	[449,464,602,546]	7	hSpCas9	negative selection	6358105
159329960	159329983	4	+	27260156	EW8	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.2900161282288556	[124]	[56,52,130,78]	-5	hSpCas9	negative selection	6415096
159322454	159322477	4	+	27260156	EW8	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.3831662424487807	[54]	[51,76,26,80]	7	hSpCas9	negative selection	6415097
159304413	159304436	4	-	27260156	EW8	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.10238615651173132	[506]	[499,403,317,331]	-2	hSpCas9	negative selection	6415098
159304399	159304422	4	+	27260156	EW8	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.23102710338666171	[309]	[331,262,213,386]	4	hSpCas9	negative selection	6479354
159322386	159322409	4	-	27260156	EW8	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.21991812941928846	[482]	[461,513,313,556]	4	hSpCas9	negative selection	6479355
159329962	159329985	4	-	27260156	EW8	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	-0.024731286198861502	[356]	[314,267,200,369]	0	hSpCas9	negative selection	6479356
159329960	159329983	4	+	27260156	CORL105	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.37388254810888455	[124]	[117,47,119,167]	-6	hSpCas9	negative selection	6536347
159322454	159322477	4	+	27260156	CORL105	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.03457828636101823	[54]	[64,64,54,76]	0	hSpCas9	negative selection	6536348
159304413	159304436	4	-	27260156	CORL105	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.010791246014105346	[506]	[523,562,606,662]	0	hSpCas9	negative selection	6536349
159304399	159304422	4	+	27260156	CORL105	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.2947871645133232	[309]	[439,397,556,403]	5	hSpCas9	negative selection	6600605
159322386	159322409	4	-	27260156	CORL105	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.21040765099204742	[482]	[740,689,663,525]	4	hSpCas9	negative selection	6600606
159329962	159329985	4	-	27260156	CORL105	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.16002251399214001	[356]	[397,426,687,387]	3	hSpCas9	negative selection	6600607
159329960	159329983	4	+	27260156	HS294T	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.42008689898534435	[124]	[69,73,26,90]	5	hSpCas9	negative selection	6657598
159322454	159322477	4	+	27260156	HS294T	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.39465606641590956	[54]	[9,12,17,25]	-5	hSpCas9	negative selection	6657599
159304413	159304436	4	-	27260156	HS294T	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.06014954632014946	[506]	[163,185,238,237]	0	hSpCas9	negative selection	6657600
159304399	159304422	4	+	27260156	HS294T	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.726238855313464	[309]	[246,227,96,217]	8	hSpCas9	negative selection	6721856
159322386	159322409	4	-	27260156	HS294T	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.792544095085508	[482]	[289,289,444,261]	8	hSpCas9	negative selection	6721857
159329962	159329985	4	-	27260156	HS294T	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.7675404930699109	[356]	[114,109,285,485]	8	hSpCas9	negative selection	6721858
159329960	159329983	4	+	27260156	HCC44	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.06521789015851032	[124]	[179,157,132,70]	-1	hSpCas9	negative selection	6778849
159322454	159322477	4	+	27260156	HCC44	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.7329855444891242	[54]	[44,29,66,14]	-8	hSpCas9	negative selection	6778850
159304413	159304436	4	-	27260156	HCC44	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.09300481779715007	[506]	[669,340,868,368]	-1	hSpCas9	negative selection	6778851
159304399	159304422	4	+	27260156	HCC44	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.07922931696178159	[309]	[388,350,455,303]	1	hSpCas9	negative selection	6843107
159322386	159322409	4	-	27260156	HCC44	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.474265247353356	[482]	[807,882,586,709]	7	hSpCas9	negative selection	6843108
159329962	159329985	4	-	27260156	HCC44	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.27017580577607286	[356]	[458,396,697,437]	4	hSpCas9	negative selection	6843109
159329960	159329983	4	+	27260156	G402	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.12252942856655924	[124]	[190,68,54,242]	-1	hSpCas9	negative selection	6900100
159322454	159322477	4	+	27260156	G402	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-1.256735065968698	[54]	[18,57,35,0]	-8	hSpCas9	negative selection	6900101
159304413	159304436	4	-	27260156	G402	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.3069476823136933	[506]	[608,836,390,210]	-4	hSpCas9	negative selection	6900102
159304399	159304422	4	+	27260156	G402	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.4027199189638683	[309]	[662,555,388,420]	5	hSpCas9	negative selection	6964358
159322386	159322409	4	-	27260156	G402	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.7746926609768858	[482]	[1144,899,1080,920]	8	hSpCas9	negative selection	6964359
159329962	159329985	4	-	27260156	G402	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.23710177944406116	[356]	[616,770,378,323]	3	hSpCas9	negative selection	6964360
159329960	159329983	4	+	27260156	L33	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.6115928325409654	[124]	[84,33,29,110]	-8	hSpCas9	negative selection	7021351
159322454	159322477	4	+	27260156	L33	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.5695153276978093	[54]	[39,35,45,125]	9	hSpCas9	negative selection	7021352
159304413	159304436	4	-	27260156	L33	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.09148771909796838	[506]	[499,178,347,669]	2	hSpCas9	negative selection	7021353
159304399	159304422	4	+	27260156	L33	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	-0.12174996881834443	[309]	[255,109,202,292]	-3	hSpCas9	negative selection	7085609
159322386	159322409	4	-	27260156	L33	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.311222454192689	[482]	[486,235,402,694]	6	hSpCas9	negative selection	7085610
159329962	159329985	4	-	27260156	L33	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.054252280702075883	[356]	[378,145,245,355]	1	hSpCas9	negative selection	7085611
159329960	159329983	4	+	27260156	K562	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.2794032446661081	[124]	[81,9,146,117]	-3	hSpCas9	negative selection	7142602
159322454	159322477	4	+	27260156	K562	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.20519581875201887	[54]	[22,104,29,15]	-3	hSpCas9	negative selection	7142603
159304413	159304436	4	-	27260156	K562	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.23425430201624425	[506]	[274,376,472,392]	-3	hSpCas9	negative selection	7142604
159304399	159304422	4	+	27260156	K562	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	1.0681502186529408	[309]	[431,920,512,458]	9	hSpCas9	negative selection	7206860
159322386	159322409	4	-	27260156	K562	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	-0.01740840615869023	[482]	[844,390,216,287]	0	hSpCas9	negative selection	7206861
159329962	159329985	4	-	27260156	K562	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.7987093080064478	[356]	[440,572,230,906]	8	hSpCas9	negative selection	7206862
159329960	159329983	4	+	27260156	HT29	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.19702483312033103	[124]	[169,110,218,187]	4	hSpCas9	negative selection	7263853
159322454	159322477	4	+	27260156	HT29	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.22637750276090918	[54]	[103,18,159,31]	4	hSpCas9	negative selection	7263854
159304413	159304436	4	-	27260156	HT29	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.13873415225407876	[506]	[945,735,538,531]	2	hSpCas9	negative selection	7263855
159304399	159304422	4	+	27260156	HT29	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.5275596373013429	[309]	[489,611,617,460]	8	hSpCas9	negative selection	7328111
159322386	159322409	4	-	27260156	HT29	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3879912455038714	[482]	[735,929,778,648]	7	hSpCas9	negative selection	7328112
159329962	159329985	4	-	27260156	HT29	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.4339818248744072	[356]	[681,652,567,465]	8	hSpCas9	negative selection	7328113
159329960	159329983	4	+	27260156	MHHES1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.8943499480285393	[124]	[70,48,106,71]	-9	hSpCas9	negative selection	7385104
159322454	159322477	4	+	27260156	MHHES1	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.28499754566105207	[54]	[5,122,59,21]	-5	hSpCas9	negative selection	7385105
159304413	159304436	4	-	27260156	MHHES1	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.04574044836446575	[506]	[829,586,378,577]	0	hSpCas9	negative selection	7385106
159304399	159304422	4	+	27260156	MHHES1	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.5078194626520156	[309]	[461,648,565,344]	8	hSpCas9	negative selection	7449362
159322386	159322409	4	-	27260156	MHHES1	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3707901070377303	[482]	[690,689,778,647]	6	hSpCas9	negative selection	7449363
159329962	159329985	4	-	27260156	MHHES1	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	-0.20719160783862828	[356]	[343,351,295,383]	-4	hSpCas9	negative selection	7449364
159329960	159329983	4	+	27260156	MEWO	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.8478167585726646	[124]	[121,57,25]	-9	hSpCas9	negative selection	7506355
159322454	159322477	4	+	27260156	MEWO	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.3297262282172557	[54]	[64,75,52]	7	hSpCas9	negative selection	7506356
159304413	159304436	4	-	27260156	MEWO	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.27369800615610207	[506]	[320,428,412]	-5	hSpCas9	negative selection	7506357
159304399	159304422	4	+	27260156	MEWO	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.2639607888807229	[309]	[529,325,223]	6	hSpCas9	negative selection	7570613
159322386	159322409	4	-	27260156	MEWO	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.10832001445979639	[482]	[501,508,452]	2	hSpCas9	negative selection	7570614
159329962	159329985	4	-	27260156	MEWO	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	-0.1772743221265995	[356]	[433,278,199]	-4	hSpCas9	negative selection	7570615
159329960	159329983	4	+	27260156	LNCAPCLONEFGC	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.5125335716672526	[124]	[83,94,56,76]	-7	hSpCas9	negative selection	7627606
159322454	159322477	4	+	27260156	LNCAPCLONEFGC	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.3056321091793204	[54]	[46,62,44,88]	5	hSpCas9	negative selection	7627607
159304413	159304436	4	-	27260156	LNCAPCLONEFGC	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.11517762575562052	[506]	[424,393,384,487]	-2	hSpCas9	negative selection	7627608
159304399	159304422	4	+	27260156	LNCAPCLONEFGC	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.31208309226748654	[309]	[329,472,365,219]	5	hSpCas9	negative selection	7691864
159322386	159322409	4	-	27260156	LNCAPCLONEFGC	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.22958272337241092	[482]	[435,409,519,694]	3	hSpCas9	negative selection	7691865
159329962	159329985	4	-	27260156	LNCAPCLONEFGC	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.2227384075889699	[356]	[405,221,545,369]	3	hSpCas9	negative selection	7691866
159329960	159329983	4	+	27260156	PANC0327	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.03482330222255636	[124]	[162,97,87,111]	0	hSpCas9	negative selection	7748857
159322454	159322477	4	+	27260156	PANC0327	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-1.6813661889148612	[54]	[20,25,5,6]	-9	hSpCas9	negative selection	7748858
159304413	159304436	4	-	27260156	PANC0327	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.4886818441616697	[506]	[249,506,302,193]	-6	hSpCas9	negative selection	7748859
159304399	159304422	4	+	27260156	PANC0327	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3177297680985334	[309]	[485,293,391,218]	5	hSpCas9	negative selection	7813115
159322386	159322409	4	-	27260156	PANC0327	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	-0.07452458773966655	[482]	[466,357,427,387]	-1	hSpCas9	negative selection	7813116
159329962	159329985	4	-	27260156	PANC0327	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.30596869543756733	[356]	[446,541,238,324]	4	hSpCas9	negative selection	7813117
159329960	159329983	4	+	27260156	NCIH2009	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.019044031195357025	[124]	[310,181,50]	0	hSpCas9	negative selection	7870108
159322454	159322477	4	+	27260156	NCIH2009	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.37509524396744265	[54]	[145,42,119]	5	hSpCas9	negative selection	7870109
159304413	159304436	4	-	27260156	NCIH2009	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.14015610253498195	[506]	[695,550,1080]	2	hSpCas9	negative selection	7870110
159304399	159304422	4	+	27260156	NCIH2009	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3235872439479992	[309]	[420,388,793]	4	hSpCas9	negative selection	7934366
159322386	159322409	4	-	27260156	NCIH2009	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.4355556345147128	[482]	[1194,759,839]	6	hSpCas9	negative selection	7934367
159329962	159329985	4	-	27260156	NCIH2009	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.17915226024875736	[356]	[749,501,478]	2	hSpCas9	negative selection	7934368
159329960	159329983	4	+	27260156	NCIH1373	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.5451654260703616	[124]	[129,98,57,26]	-5	hSpCas9	negative selection	7991359
159322454	159322477	4	+	27260156	NCIH1373	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.16926503944216842	[54]	[97,26,60,10]	-2	hSpCas9	negative selection	7991360
159304413	159304436	4	-	27260156	NCIH1373	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.28151633420491207	[506]	[532,868,1006,71]	2	hSpCas9	negative selection	7991361
159304399	159304422	4	+	27260156	NCIH1373	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.7439119599224744	[309]	[987,510,389,132]	7	hSpCas9	negative selection	8055617
159322386	159322409	4	-	27260156	NCIH1373	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.5814940113124034	[482]	[1137,642,834,178]	6	hSpCas9	negative selection	8055618
159329962	159329985	4	-	27260156	NCIH1373	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.6946013912123729	[356]	[630,596,695,174]	7	hSpCas9	negative selection	8055619
159329960	159329983	4	+	27260156	PATU8902	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.7187545017903036	[124]	[92,152,58,132]	-6	hSpCas9	negative selection	8112610
159322454	159322477	4	+	27260156	PATU8902	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.04343197681285993	[54]	[45,38,125,93]	0	hSpCas9	negative selection	8112611
159304413	159304436	4	-	27260156	PATU8902	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.07004248317209355	[506]	[678,683,752,853]	0	hSpCas9	negative selection	8112612
159304399	159304422	4	+	27260156	PATU8902	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	1.0915240714345238	[309]	[1472,928,388,1024]	9	hSpCas9	negative selection	8176868
159322386	159322409	4	-	27260156	PATU8902	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.9789209233327136	[482]	[1476,1363,878,1735]	9	hSpCas9	negative selection	8176869
159329962	159329985	4	-	27260156	PATU8902	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.6481914314671686	[356]	[1010,818,589,730]	6	hSpCas9	negative selection	8176870
159329960	159329983	4	+	27260156	PANC1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.21867657632592952	[124]	[59,68,136,96]	-4	hSpCas9	negative selection	8233861
159322454	159322477	4	+	27260156	PANC1	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.26435374191563055	[54]	[42,54,17,42]	-4	hSpCas9	negative selection	8233862
159304413	159304436	4	-	27260156	PANC1	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.07811842420298529	[506]	[561,399,274,400]	-1	hSpCas9	negative selection	8233863
159304399	159304422	4	+	27260156	PANC1	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.2094047443629139	[309]	[340,282,319,280]	3	hSpCas9	negative selection	8298119
159322386	159322409	4	-	27260156	PANC1	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.5947700834733978	[482]	[706,674,661,483]	8	hSpCas9	negative selection	8298120
159329962	159329985	4	-	27260156	PANC1	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.4722603280177151	[356]	[472,538,314,393]	7	hSpCas9	negative selection	8298121
159329960	159329983	4	+	27260156	PANC0813	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.43993848533563984	[124]	[42,90,96,190]	-6	hSpCas9	negative selection	8355112
159322454	159322477	4	+	27260156	PANC0813	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.26109720660363944	[54]	[40,37,72,61]	-4	hSpCas9	negative selection	8355113
159304413	159304436	4	-	27260156	PANC0813	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.35808748689821424	[506]	[525,378,516,442]	-5	hSpCas9	negative selection	8355114
159304399	159304422	4	+	27260156	PANC0813	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3781548700017607	[309]	[393,497,585,410]	6	hSpCas9	negative selection	8419370
159322386	159322409	4	-	27260156	PANC0813	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.4416530450923299	[482]	[819,779,624,854]	7	hSpCas9	negative selection	8419371
159329962	159329985	4	-	27260156	PANC0813	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	-0.12232309940682712	[356]	[413,353,456,321]	-2	hSpCas9	negative selection	8419372
159329960	159329983	4	+	27260156	RDES	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.13670466778955515	[124]	[127,142,131,111]	-2	hSpCas9	negative selection	8476363
159322454	159322477	4	+	27260156	RDES	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.24234031049332216	[54]	[34,73,89,9]	-4	hSpCas9	negative selection	8476364
159304413	159304436	4	-	27260156	RDES	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.05196521069484389	[506]	[520,656,614,620]	0	hSpCas9	negative selection	8476365
159304399	159304422	4	+	27260156	RDES	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.5601024408814647	[309]	[387,459,469,853]	8	hSpCas9	negative selection	8540621
159322386	159322409	4	-	27260156	RDES	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.467957248166779	[482]	[616,759,891,827]	7	hSpCas9	negative selection	8540622
159329962	159329985	4	-	27260156	RDES	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.35534935815877255	[356]	[451,490,608,559]	6	hSpCas9	negative selection	8540623
159329960	159329983	4	+	27260156	PC3	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.4739755252597999	[124]	[98,62,131,62]	-8	hSpCas9	negative selection	8597614
159322454	159322477	4	+	27260156	PC3	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.16253889578963587	[54]	[29,39,166,59]	3	hSpCas9	negative selection	8597615
159304413	159304436	4	-	27260156	PC3	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.21262485444359602	[506]	[225,306,977,512]	-5	hSpCas9	negative selection	8597616
159304399	159304422	4	+	27260156	PC3	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.2945650421718869	[309]	[316,302,521,414]	6	hSpCas9	negative selection	8661872
159322386	159322409	4	-	27260156	PC3	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.14030653851179276	[482]	[382,588,662,540]	3	hSpCas9	negative selection	8661873
159329962	159329985	4	-	27260156	PC3	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.13369098785732575	[356]	[358,413,333,389]	3	hSpCas9	negative selection	8661874
159329960	159329983	4	+	27260156	PATU8988T	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-1.0019724923606508	[124]	[78,53,35,72]	-8	hSpCas9	negative selection	8718865
159322454	159322477	4	+	27260156	PATU8988T	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.9138412494032435	[54]	[23,35,40,10]	-8	hSpCas9	negative selection	8718866
159304413	159304436	4	-	27260156	PATU8988T	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.6709097187829052	[506]	[370,181,370,292]	-8	hSpCas9	negative selection	8718867
159304399	159304422	4	+	27260156	PATU8988T	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.10749431604348703	[309]	[222,327,269,483]	1	hSpCas9	negative selection	8783123
159322386	159322409	4	-	27260156	PATU8988T	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.4555091130841619	[482]	[647,629,483,812]	7	hSpCas9	negative selection	8783124
159329962	159329985	4	-	27260156	PATU8988T	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.5979389665003845	[356]	[733,428,351,570]	8	hSpCas9	negative selection	8783125
159329960	159329983	4	+	27260156	T47D	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.18389497974406233	[124]	[142,119,154,93]	-4	hSpCas9	negative selection	8840116
159322454	159322477	4	+	27260156	T47D	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.11482952123699919	[54]	[25,67,87,95]	2	hSpCas9	negative selection	8840117
159304413	159304436	4	-	27260156	T47D	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.04203553975140546	[506]	[599,456,738,503]	-1	hSpCas9	negative selection	8840118
159304399	159304422	4	+	27260156	T47D	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3443817220611503	[309]	[437,495,475,418]	7	hSpCas9	negative selection	8904374
159322386	159322409	4	-	27260156	T47D	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.3415230368901508	[482]	[758,735,702,649]	7	hSpCas9	negative selection	8904375
159329962	159329985	4	-	27260156	T47D	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.43754152974436755	[356]	[566,528,601,556]	8	hSpCas9	negative selection	8904376
159329960	159329983	4	+	27260156	SU8686	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.36302170543009904	[124]	[103,76,88,119]	-6	hSpCas9	negative selection	8961367
159322454	159322477	4	+	27260156	SU8686	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.07531346703109376	[54]	[15,66,73,79]	1	hSpCas9	negative selection	8961368
159304413	159304436	4	-	27260156	SU8686	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.10323865674185609	[506]	[508,441,579,661]	1	hSpCas9	negative selection	8961369
159304399	159304422	4	+	27260156	SU8686	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3022754122556284	[309]	[404,326,447,330]	5	hSpCas9	negative selection	9025625
159322386	159322409	4	-	27260156	SU8686	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.5679969258853403	[482]	[639,679,664,888]	8	hSpCas9	negative selection	9025626
159329962	159329985	4	-	27260156	SU8686	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.3072883628425645	[356]	[500,299,439,533]	5	hSpCas9	negative selection	9025627
159329960	159329983	4	+	27260156	SKES1	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.34691176002093105	[124]	[128,70,91,99]	-6	hSpCas9	negative selection	9082618
159322454	159322477	4	+	27260156	SKES1	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	0.2425320213197213	[54]	[49,144,45,29]	5	hSpCas9	negative selection	9082619
159304413	159304436	4	-	27260156	SKES1	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.07330868025482715	[506]	[706,445,488,321]	-2	hSpCas9	negative selection	9082620
159304399	159304422	4	+	27260156	SKES1	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.07001221407105696	[309]	[212,489,364,240]	1	hSpCas9	negative selection	9146876
159322386	159322409	4	-	27260156	SKES1	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.31948821830417806	[482]	[507,759,550,587]	6	hSpCas9	negative selection	9146877
159329962	159329985	4	-	27260156	SKES1	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.05108927982520017	[356]	[385,425,279,387]	1	hSpCas9	negative selection	9146878
159329960	159329983	4	+	27260156	TOV112D	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.8563161716620926	[124]	[59,69,42,101]	-9	hSpCas9	negative selection	9203869
159322454	159322477	4	+	27260156	TOV112D	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.4331807150967264	[54]	[64,33,5,57]	-7	hSpCas9	negative selection	9203870
159304413	159304436	4	-	27260156	TOV112D	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	0.021531742635427037	[506]	[580,543,418,528]	0	hSpCas9	negative selection	9203871
159304399	159304422	4	+	27260156	TOV112D	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.3630308913396902	[309]	[540,494,374,225]	6	hSpCas9	negative selection	9268127
159322386	159322409	4	-	27260156	TOV112D	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.267739933112324	[482]	[559,679,609,502]	5	hSpCas9	negative selection	9268128
159329962	159329985	4	-	27260156	TOV112D	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.15888514764843303	[356]	[537,373,378,312]	3	hSpCas9	negative selection	9268129
159329960	159329983	4	+	27260156	TC71	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	-0.59978255912571	[124]	[84,118,77,70]	-9	hSpCas9	negative selection	9325120
159322454	159322477	4	+	27260156	TC71	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.060693045337090634	[54]	[39,50,55,80]	-1	hSpCas9	negative selection	9325121
159304413	159304436	4	-	27260156	TC71	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.34186578306623194	[506]	[390,355,501,466]	-7	hSpCas9	negative selection	9325122
159304399	159304422	4	+	27260156	TC71	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.09393817712860042	[309]	[328,373,340,376]	2	hSpCas9	negative selection	9389378
159322386	159322409	4	-	27260156	TC71	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.24405235521820057	[482]	[489,657,669,636]	6	hSpCas9	negative selection	9389379
159329962	159329985	4	-	27260156	TC71	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.30105138644273205	[356]	[609,430,462,372]	7	hSpCas9	negative selection	9389380
159329960	159329983	4	+	27260156	TC32	viability	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.016334490483078	[124]	[78,96,160,153]	0	hSpCas9	negative selection	9446371
159322454	159322477	4	+	27260156	TC32	viability	GGGACCATAGTGTTAAATGATGG	RAPGEF2	ENSG00000109756	-0.48339420742585215	[54]	[45,7,56,48]	-7	hSpCas9	negative selection	9446372
159304413	159304436	4	-	27260156	TC32	viability	TAGTGATACTACATCCTGAATGG	RAPGEF2	ENSG00000109756	-0.15820930389334664	[506]	[252,410,525,543]	-3	hSpCas9	negative selection	9446373
159304399	159304422	4	+	27260156	TC32	viability	CACGTTTCTTCTAGCCATTCAGG	RAPGEF2	ENSG00000109756	0.7935811308370788	[309]	[453,397,650,561]	9	hSpCas9	negative selection	9510629
159322386	159322409	4	-	27260156	TC32	viability	CCTCACTGACATTGTCATATTGG	RAPGEF2	ENSG00000109756	0.6745157844086758	[482]	[740,464,809,963]	9	hSpCas9	negative selection	9510630
159329962	159329985	4	-	27260156	TC32	viability	TTCCAGTTCGATCAAGTTCTCGG	RAPGEF2	ENSG00000109756	0.031655325959533465	[356]	[385,217,460,348]	0	hSpCas9	negative selection	9510631
159304398	159304421	4	-	27869803	HPAFII	viability after 27 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.046825073612131174	[689]	[317,421,NaN]	0	hSpCas9	negative selection	9587377
159314688	159314711	4	+	27869803	HPAFII	viability after 27 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.6308783357765146	[66]	[17,84,NaN]	5	hSpCas9	negative selection	9587378
159322434	159322457	4	+	27869803	HPAFII	viability after 27 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.7078067585957515	[441]	[408,354,NaN]	6	hSpCas9	negative selection	9587379
159329960	159329983	4	+	27869803	HPAFII	viability after 27 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.4550864611682994	[526]	[273,467,NaN]	3	hSpCas9	negative selection	9587381
159330429	159330452	4	+	27869803	HPAFII	viability after 27 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.36520129485214253	[244]	[39,149,NaN]	-3	hSpCas9	negative selection	9587382
159331738	159331761	4	+	27869803	HPAFII	viability after 27 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	-0.07307546518135044	[399]	[260,148,NaN]	0	hSpCas9	negative selection	9587383
159304398	159304421	4	-	27869803	HPAFII	viability after 15 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.18210260597568584	[689]	[763,584,NaN]	-2	hSpCas9	negative selection	9669826
159314688	159314711	4	+	27869803	HPAFII	viability after 15 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	1.247952997689468	[66]	[199,152,NaN]	9	hSpCas9	negative selection	9669827
159322434	159322457	4	+	27869803	HPAFII	viability after 15 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.4678571984864601	[441]	[931,485,NaN]	5	hSpCas9	negative selection	9669828
159329960	159329983	4	+	27869803	HPAFII	viability after 15 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.4629707813468611	[526]	[1014,634,NaN]	5	hSpCas9	negative selection	9669830
159330429	159330452	4	+	27869803	HPAFII	viability after 15 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.16007682056660277	[244]	[292,199,NaN]	-2	hSpCas9	negative selection	9669831
159331738	159331761	4	+	27869803	HPAFII	viability after 15 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.24240381327279736	[399]	[814,317,NaN]	2	hSpCas9	negative selection	9669832
159304398	159304421	4	-	27869803	ASPC1	viability after 36 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.13895622974250943	[1364]	[288,496,477]	-1	hSpCas9	negative selection	9752275
159314688	159314711	4	+	27869803	ASPC1	viability after 36 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	-0.3387187465720425	[292]	[152,59,45]	-3	hSpCas9	negative selection	9752276
159322434	159322457	4	+	27869803	ASPC1	viability after 36 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	-0.03170727577567578	[959]	[171,431,350]	0	hSpCas9	negative selection	9752277
159329960	159329983	4	+	27869803	ASPC1	viability after 36 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.8591338915303961	[1501]	[398,2248,297]	8	hSpCas9	negative selection	9752279
159330429	159330452	4	+	27869803	ASPC1	viability after 36 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.40142580857505483	[511]	[168,222,290]	4	hSpCas9	negative selection	9752280
159331738	159331761	4	+	27869803	ASPC1	viability after 36 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.04834150362330192	[892]	[373,355,255]	0	hSpCas9	negative selection	9752281
159304398	159304421	4	-	27869803	PATU8988S	viability after 35 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.8546653026949302	[1486]	[1080,1084,NaN]	8	hSpCas9	negative selection	9834724
159314688	159314711	4	+	27869803	PATU8988S	viability after 35 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.2098657852658271	[247]	[124,105,NaN]	2	hSpCas9	negative selection	9834725
159322434	159322457	4	+	27869803	PATU8988S	viability after 35 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	1.2263929119349193	[828]	[875,685,NaN]	9	hSpCas9	negative selection	9834726
159329960	159329983	4	+	27869803	PATU8988S	viability after 35 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.0849226939361365	[1298]	[507,601,NaN]	1	hSpCas9	negative selection	9834728
159330429	159330452	4	+	27869803	PATU8988S	viability after 35 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.5033019659387792	[429]	[235,254,NaN]	5	hSpCas9	negative selection	9834729
159331738	159331761	4	+	27869803	PATU8988S	viability after 35 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.1222772946765101	[743]	[391,259,NaN]	1	hSpCas9	negative selection	9834730
159304398	159304421	4	-	27869803	PATU8988S	viability after 31 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.7357445766354411	[1486]	[711,1337,NaN]	8	hSpCas9	negative selection	9917173
159314688	159314711	4	+	27869803	PATU8988S	viability after 31 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.01550536760924226	[247]	[84,118,NaN]	0	hSpCas9	negative selection	9917174
159322434	159322457	4	+	27869803	PATU8988S	viability after 31 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	1.0760894615676406	[828]	[699,692,NaN]	9	hSpCas9	negative selection	9917175
159329960	159329983	4	+	27869803	PATU8988S	viability after 31 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.23506174539089897	[1298]	[346,943,NaN]	3	hSpCas9	negative selection	9917177
159330429	159330452	4	+	27869803	PATU8988S	viability after 31 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	0.009570577632392219	[429]	[176,166,NaN]	0	hSpCas9	negative selection	9917178
159331738	159331761	4	+	27869803	PATU8988S	viability after 31 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.2725489875884524	[743]	[327,396,NaN]	3	hSpCas9	negative selection	9917179
159304398	159304421	4	-	27869803	HPAFII	viability after 35 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	0.1428663638505101	[689]	[316,462,NaN]	0	hSpCas9	negative selection	9999622
159314688	159314711	4	+	27869803	HPAFII	viability after 35 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	1.0065616224011573	[66]	[6,136,NaN]	6	hSpCas9	negative selection	9999623
159322434	159322457	4	+	27869803	HPAFII	viability after 35 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.9257465157940012	[441]	[449,396,NaN]	6	hSpCas9	negative selection	9999624
159329960	159329983	4	+	27869803	HPAFII	viability after 35 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.6733308055245022	[526]	[297,568,NaN]	4	hSpCas9	negative selection	9999626
159330429	159330452	4	+	27869803	HPAFII	viability after 35 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.6380487216908415	[244]	[66,93,NaN]	-4	hSpCas9	negative selection	9999627
159331738	159331761	4	+	27869803	HPAFII	viability after 35 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.34782313253344266	[399]	[260,253,NaN]	2	hSpCas9	negative selection	9999628
159304398	159304421	4	-	27869803	HPAFII	viability after 31 days	CTGAATGGCTAGAAGAAACGTGG	RAPGEF2	ENSG00000109756	-0.01690355721200998	[689]	[264,510,NaN]	0	hSpCas9	negative selection	10082071
159314688	159314711	4	+	27869803	HPAFII	viability after 31 days	CATCAGATCCTCTGATGAGCAGG	RAPGEF2	ENSG00000109756	0.9876948879309254	[66]	[8,145,NaN]	7	hSpCas9	negative selection	10082072
159322434	159322457	4	+	27869803	HPAFII	viability after 31 days	TCGCAGTGGTGGAAAGAGCAGGG	RAPGEF2	ENSG00000109756	0.8803008267362535	[441]	[447,465,NaN]	6	hSpCas9	negative selection	10082073
159329960	159329983	4	+	27869803	HPAFII	viability after 31 days	CACCGAGAACTTGATCGAACTGG	RAPGEF2	ENSG00000109756	0.5434473698930171	[526]	[208,672,NaN]	4	hSpCas9	negative selection	10082075
159330429	159330452	4	+	27869803	HPAFII	viability after 31 days	TCTTTCTAGCCCAATGGAAGTGG	RAPGEF2	ENSG00000109756	-0.23572322825162056	[244]	[66,170,NaN]	-2	hSpCas9	negative selection	10082076
159331738	159331761	4	+	27869803	HPAFII	viability after 31 days	TTACTTGGAGGCTCTGAGAAGGG	RAPGEF2	ENSG00000109756	0.1587576143350311	[399]	[263,235,NaN]	1	hSpCas9	negative selection	10082077
159353897	159353920	4	+	28162770	P31FUJ	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.8667334691365358	[202]	[434]	8	hSpCas9	negative selection	10222252
159323581	159323604	4	+	28162770	P31FUJ	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.3916886604934149	[503]	[776]	4	hSpCas9	negative selection	10222253
159355953	159355976	4	+	28162770	P31FUJ	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.5041633897518274	[29]	[49]	6	hSpCas9	negative selection	10222254
159304387	159304410	4	-	28162770	P31FUJ	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.5688690791396428	[108]	[189]	6	hSpCas9	negative selection	10222255
159304397	159304420	4	-	28162770	P31FUJ	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	1.445269700698259	[49]	[159]	9	hSpCas9	negative selection	10222256
159314626	159314649	4	+	28162770	P31FUJ	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.13418316545832343	[144]	[186]	1	hSpCas9	negative selection	10222257
159314716	159314739	4	+	28162770	P31FUJ	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.06453072182457986	[96]	[108]	0	hSpCas9	negative selection	10222258
159346905	159346928	4	+	28162770	P31FUJ	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	-0.12129388919738815	[335]	[362]	-1	hSpCas9	negative selection	10222259
159346939	159346962	4	-	28162770	P31FUJ	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.16335728465877605	[249]	[328]	1	hSpCas9	negative selection	10222260
159352835	159352858	4	+	28162770	P31FUJ	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.33497053500926244	[590]	[875]	3	hSpCas9	negative selection	10222261
159353897	159353920	4	+	28162770	TF1	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10391618
159323581	159323604	4	+	28162770	TF1	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[523]	1	hSpCas9	negative selection	10391619
159355953	159355976	4	+	28162770	TF1	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10391620
159304387	159304410	4	-	28162770	TF1	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10391621
159304397	159304420	4	-	28162770	TF1	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10391622
159314626	159314649	4	+	28162770	TF1	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10391623
159314716	159314739	4	+	28162770	TF1	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10391624
159346905	159346928	4	+	28162770	TF1	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10391625
159346939	159346962	4	-	28162770	TF1	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10391626
159352835	159352858	4	+	28162770	TF1	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	NaN	[NaN]	[535]	1	hSpCas9	negative selection	10391627
159353897	159353920	4	+	28162770	SKM1	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.37593767958990354	[50]	[116]	3	hSpCas9	negative selection	10560984
159323581	159323604	4	+	28162770	SKM1	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.24539758726358096	[114]	[240]	2	hSpCas9	negative selection	10560985
159355953	159355976	4	+	28162770	SKM1	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.17799830197799427	[8]	[17]	1	hSpCas9	negative selection	10560986
159304387	159304410	4	-	28162770	SKM1	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10560987
159304397	159304420	4	-	28162770	SKM1	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.7730920975410591	[28]	[29]	-5	hSpCas9	negative selection	10560988
159314626	159314649	4	+	28162770	SKM1	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.7156550879207939	[30]	[89]	7	hSpCas9	negative selection	10560989
159314716	159314739	4	+	28162770	SKM1	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.9919266994643178	[35]	[31]	-6	hSpCas9	negative selection	10560990
159346905	159346928	4	+	28162770	SKM1	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.1779983019779946	[66]	[133]	1	hSpCas9	negative selection	10560991
159346939	159346962	4	-	28162770	SKM1	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.04871528503302813	[69]	[127]	0	hSpCas9	negative selection	10560992
159352835	159352858	4	+	28162770	SKM1	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	-0.0007671869581953317	[132]	[234]	0	hSpCas9	negative selection	10560993
159353897	159353920	4	+	28162770	SKM1	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.37593767958990354	[50]	[116]	3	hSpCas9	negative selection	10730350
159323581	159323604	4	+	28162770	SKM1	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.24539758726358096	[114]	[240]	2	hSpCas9	negative selection	10730351
159355953	159355976	4	+	28162770	SKM1	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.17799830197799427	[8]	[17]	1	hSpCas9	negative selection	10730352
159304387	159304410	4	-	28162770	SKM1	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10730353
159304397	159304420	4	-	28162770	SKM1	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.7730920975410591	[28]	[29]	-5	hSpCas9	negative selection	10730354
159314626	159314649	4	+	28162770	SKM1	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.7156550879207939	[30]	[89]	7	hSpCas9	negative selection	10730355
159314716	159314739	4	+	28162770	SKM1	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.9919266994643178	[35]	[31]	-6	hSpCas9	negative selection	10730356
159346905	159346928	4	+	28162770	SKM1	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.1779983019779946	[66]	[133]	1	hSpCas9	negative selection	10730357
159346939	159346962	4	-	28162770	SKM1	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.04871528503302813	[69]	[127]	0	hSpCas9	negative selection	10730358
159352835	159352858	4	+	28162770	SKM1	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	-0.0007671869581953317	[132]	[234]	0	hSpCas9	negative selection	10730359
159353897	159353920	4	+	28162770	PL21	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.06131190979200343	[217]	[98]	0	hSpCas9	negative selection	10899716
159323581	159323604	4	+	28162770	PL21	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.21307867019681836	[332]	[167]	2	hSpCas9	negative selection	10899717
159355953	159355976	4	+	28162770	PL21	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	1.422532035825768	[35]	[41]	9	hSpCas9	negative selection	10899718
159304387	159304410	4	-	28162770	PL21	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	1.0683497419337789	[125]	[114]	8	hSpCas9	negative selection	10899719
159304397	159304420	4	-	28162770	PL21	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-1.0177654158548135	[106]	[22]	-6	hSpCas9	negative selection	10899720
159314626	159314649	4	+	28162770	PL21	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.22385568346312779	[180]	[91]	2	hSpCas9	negative selection	10899721
159314716	159314739	4	+	28162770	PL21	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.03412966305039089	[91]	[40]	0	hSpCas9	negative selection	10899722
159346905	159346928	4	+	28162770	PL21	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.57865123774305	[199]	[129]	5	hSpCas9	negative selection	10899723
159346939	159346962	4	-	28162770	PL21	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.3582044607215715	[189]	[105]	3	hSpCas9	negative selection	10899724
159352835	159352858	4	+	28162770	PL21	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.24422068295343724	[418]	[215]	2	hSpCas9	negative selection	10899725
159353897	159353920	4	+	28162770	P31FUJ	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.8667334691365358	[202]	[434]	8	hSpCas9	negative selection	11069082
159323581	159323604	4	+	28162770	P31FUJ	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.3916886604934149	[503]	[776]	4	hSpCas9	negative selection	11069083
159355953	159355976	4	+	28162770	P31FUJ	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.5041633897518274	[29]	[49]	6	hSpCas9	negative selection	11069084
159304387	159304410	4	-	28162770	P31FUJ	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.5688690791396428	[108]	[189]	6	hSpCas9	negative selection	11069085
159304397	159304420	4	-	28162770	P31FUJ	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	1.445269700698259	[49]	[159]	9	hSpCas9	negative selection	11069086
159314626	159314649	4	+	28162770	P31FUJ	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.13418316545832343	[144]	[186]	1	hSpCas9	negative selection	11069087
159314716	159314739	4	+	28162770	P31FUJ	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.06453072182457986	[96]	[108]	0	hSpCas9	negative selection	11069088
159346905	159346928	4	+	28162770	P31FUJ	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	-0.12129388919738815	[335]	[362]	-1	hSpCas9	negative selection	11069089
159346939	159346962	4	-	28162770	P31FUJ	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.16335728465877605	[249]	[328]	1	hSpCas9	negative selection	11069090
159352835	159352858	4	+	28162770	P31FUJ	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.33497053500926244	[590]	[875]	3	hSpCas9	negative selection	11069091
159353897	159353920	4	+	28162770	OCIAML5	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.3952434826767802	[122]	[291]	3	hSpCas9	negative selection	11238448
159323581	159323604	4	+	28162770	OCIAML5	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	-0.10312833503171492	[287]	[483]	0	hSpCas9	negative selection	11238449
159355953	159355976	4	+	28162770	OCIAML5	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	1.7668432617804966	[6]	[42]	9	hSpCas9	negative selection	11238450
159304387	159304410	4	-	28162770	OCIAML5	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.2183227570274009	[79]	[167]	1	hSpCas9	negative selection	11238451
159304397	159304420	4	-	28162770	OCIAML5	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.2502951467656809	[33]	[72]	2	hSpCas9	negative selection	11238452
159314626	159314649	4	+	28162770	OCIAML5	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.5828704858525517	[80]	[218]	5	hSpCas9	negative selection	11238453
159314716	159314739	4	+	28162770	OCIAML5	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	1.4749147517496508	[56]	[285]	9	hSpCas9	negative selection	11238454
159346905	159346928	4	+	28162770	OCIAML5	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.1706535056360866	[188]	[383]	1	hSpCas9	negative selection	11238455
159346939	159346962	4	-	28162770	OCIAML5	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	1.215678035771837	[77]	[326]	9	hSpCas9	negative selection	11238456
159352835	159352858	4	+	28162770	OCIAML5	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.6415807631112131	[249]	[703]	5	hSpCas9	negative selection	11238457
159353897	159353920	4	+	28162770	EOL1	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.10664144634454009	[445]	[252]	1	hSpCas9	negative selection	11407814
159323581	159323604	4	+	28162770	EOL1	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.7059074850951943	[447]	[384]	6	hSpCas9	negative selection	11407815
159355953	159355976	4	+	28162770	EOL1	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	-0.6604147291506217	[74]	[24]	-5	hSpCas9	negative selection	11407816
159304387	159304410	4	-	28162770	EOL1	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.09910349649411077	[245]	[120]	0	hSpCas9	negative selection	11407817
159304397	159304420	4	-	28162770	EOL1	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.5404042802374744	[153]	[117]	5	hSpCas9	negative selection	11407818
159314626	159314649	4	+	28162770	EOL1	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.4323867731447411	[291]	[113]	-3	hSpCas9	negative selection	11407819
159314716	159314739	4	+	28162770	EOL1	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.7084143407057689	[114]	[98]	6	hSpCas9	negative selection	11407820
159346905	159346928	4	+	28162770	EOL1	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	-0.28799686380956613	[291]	[125]	-2	hSpCas9	negative selection	11407821
159346939	159346962	4	-	28162770	EOL1	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	-0.34079679495046045	[249]	[103]	-3	hSpCas9	negative selection	11407822
159352835	159352858	4	+	28162770	EOL1	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.23649177788527476	[521]	[323]	2	hSpCas9	negative selection	11407823
159353897	159353920	4	+	28162770	MOLM13	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.8829268808234227	[335]	[447]	6	hSpCas9	negative selection	11577180
159323581	159323604	4	+	28162770	MOLM13	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.15861950952816395	[538]	[434]	1	hSpCas9	negative selection	11577181
159355953	159355976	4	+	28162770	MOLM13	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	-0.8387719566894729	[46]	[18]	-4	hSpCas9	negative selection	11577182
159304387	159304410	4	-	28162770	MOLM13	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.23571761567519645	[170]	[104]	-1	hSpCas9	negative selection	11577183
159304397	159304420	4	-	28162770	MOLM13	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.23539308636533862	[126]	[77]	-1	hSpCas9	negative selection	11577184
159314626	159314649	4	+	28162770	MOLM13	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.3982551937075265	[190]	[181]	3	hSpCas9	negative selection	11577185
159314716	159314739	4	+	28162770	MOLM13	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.6339902324746347	[175]	[81]	-4	hSpCas9	negative selection	11577186
159346905	159346928	4	+	28162770	MOLM13	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	-0.9816719930686572	[436]	[159]	-5	hSpCas9	negative selection	11577187
159346939	159346962	4	-	28162770	MOLM13	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.78770981346995	[273]	[341]	6	hSpCas9	negative selection	11577188
159352835	159352858	4	+	28162770	MOLM13	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.14541387817374152	[658]	[526]	1	hSpCas9	negative selection	11577189
159353897	159353920	4	+	28162770	HEL	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.32200849147061666	[300]	[240]	2	hSpCas9	negative selection	11746546
159323581	159323604	4	+	28162770	HEL	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	-0.030354578999464366	[404]	[253]	0	hSpCas9	negative selection	11746547
159355953	159355976	4	+	28162770	HEL	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	0.2969639951586269	[60]	[47]	2	hSpCas9	negative selection	11746548
159304387	159304410	4	-	28162770	HEL	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.13486874666319526	[191]	[111]	-1	hSpCas9	negative selection	11746549
159304397	159304420	4	-	28162770	HEL	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.8437863509384498	[106]	[122]	7	hSpCas9	negative selection	11746550
159314626	159314649	4	+	28162770	HEL	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.3572611679996429	[207]	[103]	-2	hSpCas9	negative selection	11746551
159314716	159314739	4	+	28162770	HEL	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.32249574983896645	[122]	[62]	-2	hSpCas9	negative selection	11746552
159346905	159346928	4	+	28162770	HEL	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	-1.2277504350032387	[361]	[98]	-6	hSpCas9	negative selection	11746553
159346939	159346962	4	-	28162770	HEL	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	-0.21063625428115995	[214]	[118]	-1	hSpCas9	negative selection	11746554
159352835	159352858	4	+	28162770	HEL	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	-0.5112587053855624	[562]	[252]	-3	hSpCas9	negative selection	11746555
159353897	159353920	4	+	28162770	MV411	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.1851532725284328	[212]	[203]	1	hSpCas9	negative selection	11915912
159323581	159323604	4	+	28162770	MV411	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	-0.20283712855260982	[372]	[272]	-1	hSpCas9	negative selection	11915913
159355953	159355976	4	+	28162770	MV411	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	1.1492571568438719	[37]	[70]	8	hSpCas9	negative selection	11915914
159304387	159304410	4	-	28162770	MV411	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.2685775962208895	[142]	[99]	-2	hSpCas9	negative selection	11915915
159304397	159304420	4	-	28162770	MV411	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	-0.7525624492172245	[51]	[25]	-5	hSpCas9	negative selection	11915916
159314626	159314649	4	+	28162770	MV411	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.14804715107466804	[170]	[129]	-1	hSpCas9	negative selection	11915917
159314716	159314739	4	+	28162770	MV411	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.284576069989422	[106]	[73]	-2	hSpCas9	negative selection	11915918
159346905	159346928	4	+	28162770	MV411	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.5268199507040527	[233]	[283]	5	hSpCas9	negative selection	11915919
159346939	159346962	4	-	28162770	MV411	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.19057521382709897	[206]	[198]	1	hSpCas9	negative selection	11915920
159352835	159352858	4	+	28162770	MV411	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.5839889801403209	[372]	[470]	5	hSpCas9	negative selection	11915921
159353897	159353920	4	+	28162770	MONOMAC1	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.6089877890200802	[154]	[270]	6	hSpCas9	negative selection	12085278
159323581	159323604	4	+	28162770	MONOMAC1	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	1.1814747761941762	[224]	[584]	8	hSpCas9	negative selection	12085279
159355953	159355976	4	+	28162770	MONOMAC1	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	-0.7060504945474115	[36]	[25]	-5	hSpCas9	negative selection	12085280
159304387	159304410	4	-	28162770	MONOMAC1	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	-0.5349064858159378	[90]	[71]	-4	hSpCas9	negative selection	12085281
159304397	159304420	4	-	28162770	MONOMAC1	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.6600051990984033	[52]	[95]	6	hSpCas9	negative selection	12085282
159314626	159314649	4	+	28162770	MONOMAC1	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	-0.9245109922484621	[100]	[60]	-6	hSpCas9	negative selection	12085283
159314716	159314739	4	+	28162770	MONOMAC1	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	0.501307453079345	[52]	[85]	5	hSpCas9	negative selection	12085284
159346905	159346928	4	+	28162770	MONOMAC1	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.37975172221590237	[117]	[175]	4	hSpCas9	negative selection	12085285
159346939	159346962	4	-	28162770	MONOMAC1	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.8544934535805284	[109]	[227]	7	hSpCas9	negative selection	12085286
159352835	159352858	4	+	28162770	MONOMAC1	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.011851309927146447	[275]	[318]	0	hSpCas9	negative selection	12085287
159353897	159353920	4	+	28162770	OCIAML2	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	0.6329928058319965	[46]	[403]	6	hSpCas9	negative selection	12254644
159323581	159323604	4	+	28162770	OCIAML2	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	0.18541577354047745	[65]	[415]	1	hSpCas9	negative selection	12254645
159355953	159355976	4	+	28162770	OCIAML2	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	1.1314061888379363	[6]	[84]	9	hSpCas9	negative selection	12254646
159304387	159304410	4	-	28162770	OCIAML2	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.05293213081485171	[23]	[137]	0	hSpCas9	negative selection	12254647
159304397	159304420	4	-	28162770	OCIAML2	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.2031419424368509	[20]	[133]	2	hSpCas9	negative selection	12254648
159314626	159314649	4	+	28162770	OCIAML2	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.6394237202227524	[40]	[353]	6	hSpCas9	negative selection	12254649
159314716	159314739	4	+	28162770	OCIAML2	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.9035892325182675	[26]	[79]	-6	hSpCas9	negative selection	12254650
159346905	159346928	4	+	28162770	OCIAML2	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.22363131796980676	[35]	[232]	2	hSpCas9	negative selection	12254651
159346939	159346962	4	-	28162770	OCIAML2	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.800672196575233	[28]	[279]	7	hSpCas9	negative selection	12254652
159352835	159352858	4	+	28162770	OCIAML2	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	-0.0163171772298778	[76]	[421]	0	hSpCas9	negative selection	12254653
159353897	159353920	4	+	28162770	OCIAML3	viability	ACACAGGCACAATAAAGCGGAGG	RAPGEF2	ENSG00000109756	-0.3080987682377825	[72]	[177]	-2	hSpCas9	negative selection	12424010
159323581	159323604	4	+	28162770	OCIAML3	viability	GAAAGGAGTGATGAGAACAAAGG	RAPGEF2	ENSG00000109756	-0.2991732063190759	[85]	[210]	-2	hSpCas9	negative selection	12424011
159355953	159355976	4	+	28162770	OCIAML3	viability	GAAACCGCCGGACTACAACGTGG	RAPGEF2	ENSG00000109756	-1.2720795454368008	[3]	[4]	-7	hSpCas9	negative selection	12424012
159304387	159304410	4	-	28162770	OCIAML3	viability	GAAGAAACGTGGGTCACCTGTGG	RAPGEF2	ENSG00000109756	0.1974057378644194	[25]	[89]	1	hSpCas9	negative selection	12424013
159304397	159304420	4	-	28162770	OCIAML3	viability	TGAATGGCTAGAAGAAACGTGGG	RAPGEF2	ENSG00000109756	0.10198617278573674	[24]	[80]	1	hSpCas9	negative selection	12424014
159314626	159314649	4	+	28162770	OCIAML3	viability	TGGGTTGCCAGAAACAGCAGTGG	RAPGEF2	ENSG00000109756	0.7832972115995723	[45]	[238]	7	hSpCas9	negative selection	12424015
159314716	159314739	4	+	28162770	OCIAML3	viability	TGTGAGAGACTGCCTAGAGAAGG	RAPGEF2	ENSG00000109756	-0.8835142575191479	[32]	[53]	-6	hSpCas9	negative selection	12424016
159346905	159346928	4	+	28162770	OCIAML3	viability	CCAGCACATAAAATCAACCAGGG	RAPGEF2	ENSG00000109756	0.15380533607903546	[52]	[177]	1	hSpCas9	negative selection	12424017
159346939	159346962	4	-	28162770	OCIAML3	viability	TGAAGGATAAAGGGACACGGCGG	RAPGEF2	ENSG00000109756	0.6036381186765991	[62]	[288]	5	hSpCas9	negative selection	12424018
159352835	159352858	4	+	28162770	OCIAML3	viability	GCATCGTGGAAACAAACCTAGGG	RAPGEF2	ENSG00000109756	0.3853187914110867	[122]	[484]	3	hSpCas9	negative selection	12424019