Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5931
• Symbol: RBBP7
• Description: RB binding protein 7, chromatin remodeling factor

DataSource: http://genomecrispr.dkfz.de/#!/results/RBBP7

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
16852833	16852856	X	+	26472758	Jiyoye	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.32732207381665857	[129]	[122]	2	hSpCas9	negative selection	134172
16857655	16857678	X	-	26472758	Jiyoye	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	1.000358389031998	[174]	[263]	6	hSpCas9	negative selection	134173
16853802	16853825	X	-	26472758	Jiyoye	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.0592520780855665	[20]	[32]	7	hSpCas9	negative selection	134174
16845859	16845882	X	+	26472758	Jiyoye	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.1930505761530259	[260]	[224]	1	hSpCas9	negative selection	134175
16869200	16869223	X	-	26472758	Jiyoye	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.19327775433488092	[507]	[437]	1	hSpCas9	negative selection	134176
16852079	16852102	X	-	26472758	Jiyoye	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	-0.30784765977965567	[86]	[52]	-2	hSpCas9	negative selection	134177
16852050	16852073	X	+	26472758	Jiyoye	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.5188240370503496	[132]	[69]	-4	hSpCas9	negative selection	134178
16845876	16845899	X	-	26472758	Jiyoye	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.5258198780044925	[34]	[37]	4	hSpCas9	negative selection	134179
16869107	16869130	X	+	26472758	Jiyoye	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.65159410917232	[194]	[230]	5	hSpCas9	negative selection	134180
16863024	16863047	X	-	26472758	Jiyoye	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.06203989545718591	[46]	[36]	0	hSpCas9	negative selection	134181
16852833	16852856	X	+	26472758	KBM7	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.12442307426639695	[354,425]	[259,151]	1	hSpCas9	negative selection	325290
16857655	16857678	X	-	26472758	KBM7	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.33687945325249014	[1047,1047]	[787,479]	3	hSpCas9	negative selection	325291
16853802	16853825	X	-	26472758	KBM7	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-0.2200975173412285	[28,63]	[17,20]	-2	hSpCas9	negative selection	325292
16845859	16845882	X	+	26472758	KBM7	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.1883404268467893	[959,759]	[428,482]	2	hSpCas9	negative selection	325293
16869200	16869223	X	-	26472758	KBM7	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.05118137827581015	[2269,1451]	[741,907]	0	hSpCas9	negative selection	325294
16852079	16852102	X	-	26472758	KBM7	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.06325422680481185	[336,290]	[184,125]	0	hSpCas9	negative selection	325295
16852050	16852073	X	+	26472758	KBM7	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.3184301976329531	[687,462]	[152,267]	-3	hSpCas9	negative selection	325296
16845876	16845899	X	-	26472758	KBM7	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.9611624389939395	[141,109]	[153,78]	9	hSpCas9	negative selection	325297
16869107	16869130	X	+	26472758	KBM7	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.16662827555807735	[901,848]	[455,468]	1	hSpCas9	negative selection	325298
16863024	16863047	X	-	26472758	KBM7	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.5177471541214915	[155,205]	[96,27]	-4	hSpCas9	negative selection	325299
16852833	16852856	X	+	26472758	Raji	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.32977595671004745	[287]	[83]	3	hSpCas9	negative selection	516408
16857655	16857678	X	-	26472758	Raji	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.6579729922733517	[537]	[196]	6	hSpCas9	negative selection	516409
16853802	16853825	X	-	26472758	Raji	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-2.046421800705436	[88]	[4]	-8	hSpCas9	negative selection	516410
16845859	16845882	X	+	26472758	Raji	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.6770329806002515	[441]	[163]	6	hSpCas9	negative selection	516411
16869200	16869223	X	-	26472758	Raji	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.6409177972877529	[770]	[278]	6	hSpCas9	negative selection	516412
16852079	16852102	X	-	26472758	Raji	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.6500352312367914	[172]	[62]	6	hSpCas9	negative selection	516413
16852050	16852073	X	+	26472758	Raji	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.46635170992430236	[255]	[42]	-4	hSpCas9	negative selection	516414
16845876	16845899	X	-	26472758	Raji	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.0030468755588637375	[85]	[19]	0	hSpCas9	negative selection	516415
16869107	16869130	X	+	26472758	Raji	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.2817137159359129	[435]	[122]	2	hSpCas9	negative selection	516416
16863024	16863047	X	-	26472758	Raji	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.8416325359075958	[138]	[17]	-6	hSpCas9	negative selection	516417
16852833	16852856	X	+	26472758	K562	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	1.0047483148981635	[342]	[580]	8	hSpCas9	negative selection	707526
16857655	16857678	X	-	26472758	K562	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.7020525952413501	[875]	[1202]	6	hSpCas9	negative selection	707527
16853802	16853825	X	-	26472758	K562	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	0.8207680980828951	[111]	[166]	6	hSpCas9	negative selection	707528
16845859	16845882	X	+	26472758	K562	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.6545928150262509	[519]	[690]	5	hSpCas9	negative selection	707529
16869200	16869223	X	-	26472758	K562	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.719679943787904	[1647]	[2290]	6	hSpCas9	negative selection	707530
16852079	16852102	X	-	26472758	K562	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.6612584695792763	[199]	[266]	5	hSpCas9	negative selection	707531
16852050	16852073	X	+	26472758	K562	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.6594562269452906	[464]	[619]	5	hSpCas9	negative selection	707532
16845876	16845899	X	-	26472758	K562	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.49105869524957213	[176]	[209]	4	hSpCas9	negative selection	707533
16869107	16869130	X	+	26472758	K562	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.7730488000202835	[765]	[1104]	6	hSpCas9	negative selection	707534
16863024	16863047	X	-	26472758	K562	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.5797052054088282	[171]	[216]	5	hSpCas9	negative selection	707535
16852746	16852769	X	+	26627737	DLD1	viability	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.6085207154515271	[374]	[90,67,71]	-5	hSpCas9	negative selection	845223
16853713	16853736	X	+	26627737	DLD1	viability	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.692168360610587	[381]	[277,133,167]	7	hSpCas9	negative selection	845224
16858754	16858777	X	+	26627737	DLD1	viability	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.5310399190432082	[920]	[292,133,171]	-5	hSpCas9	negative selection	845225
16862955	16862978	X	+	26627737	DLD1	viability	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.039146827791360916	[2320]	[723,1061,501]	0	hSpCas9	negative selection	845226
16869090	16869113	X	+	26627737	DLD1	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-0.4537516998115593	[235]	[86,47,29]	-4	hSpCas9	negative selection	845227
16869504	16869527	X	+	26627737	DLD1	viability	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.5784660087337211	[266]	[75,47,44]	-5	hSpCas9	negative selection	845228
16852746	16852769	X	+	26627737	GBM cells	viability after 5 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.5015783773403008	[161]	[130,114]	7	hSpCas9	negative selection	927538
16853713	16853736	X	+	26627737	GBM cells	viability after 5 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.8821706110511094	[129]	[134,121]	9	hSpCas9	negative selection	927539
16858754	16858777	X	+	26627737	GBM cells	viability after 5 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.389324109570183	[288]	[156,248]	6	hSpCas9	negative selection	927540
16862955	16862978	X	+	26627737	GBM cells	viability after 5 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.06689293704423172	[1500]	[757,778]	-1	hSpCas9	negative selection	927541
16869090	16869113	X	+	26627737	GBM cells	viability after 5 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.18496493344445125	[227]	[89,187]	3	hSpCas9	negative selection	927542
16869504	16869527	X	+	26627737	GBM cells	viability after 5 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.5962939730771416	[147]	[43,60]	-7	hSpCas9	negative selection	927543
16852746	16852769	X	+	26627737	GBM cells	viability after 13 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.08731588324181683	[161]	[106,62]	-1	hSpCas9	negative selection	1009853
16853713	16853736	X	+	26627737	GBM cells	viability after 13 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.8380251711166263	[129]	[92,152]	8	hSpCas9	negative selection	1009854
16858754	16858777	X	+	26627737	GBM cells	viability after 13 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.20520533453540657	[288]	[209,156]	2	hSpCas9	negative selection	1009855
16862955	16862978	X	+	26627737	GBM cells	viability after 13 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.0922393747774759	[1500]	[1101,677]	1	hSpCas9	negative selection	1009856
16869090	16869113	X	+	26627737	GBM cells	viability after 13 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.4326632944382437	[227]	[177,157]	5	hSpCas9	negative selection	1009857
16869504	16869527	X	+	26627737	GBM cells	viability after 13 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.28875396723016167	[147]	[89,45]	-3	hSpCas9	negative selection	1009858
16852746	16852769	X	+	26627737	GBM cells	viability after 21 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.6273745919595615	[161]	[136,134]	6	hSpCas9	negative selection	1092168
16853713	16853736	X	+	26627737	GBM cells	viability after 21 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.5368763406694567	[129]	[114,90]	5	hSpCas9	negative selection	1092169
16858754	16858777	X	+	26627737	GBM cells	viability after 21 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.8735618655727784	[288]	[271,301]	8	hSpCas9	negative selection	1092170
16862955	16862978	X	+	26627737	GBM cells	viability after 21 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.3866671276354001	[1500]	[1133,1003]	4	hSpCas9	negative selection	1092171
16869090	16869113	X	+	26627737	GBM cells	viability after 21 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.7776058392568659	[227]	[215,208]	7	hSpCas9	negative selection	1092172
16869504	16869527	X	+	26627737	GBM cells	viability after 21 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-1.535093056414754	[147]	[21,32]	-8	hSpCas9	negative selection	1092173
16852746	16852769	X	+	26627737	RPE1	viability after 9 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.7104799622563863	[482]	[77,110]	-5	hSpCas9	negative selection	1174483
16853713	16853736	X	+	26627737	RPE1	viability after 9 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.36859005021888447	[569]	[177,297]	2	hSpCas9	negative selection	1174484
16858754	16858777	X	+	26627737	RPE1	viability after 9 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.5990166902918996	[1045]	[220,209]	-4	hSpCas9	negative selection	1174485
16862955	16862978	X	+	26627737	RPE1	viability after 9 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.7123533815394583	[4582]	[721,1073]	-5	hSpCas9	negative selection	1174486
16869090	16869113	X	+	26627737	RPE1	viability after 9 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.6130981536470095	[330]	[347,276]	8	hSpCas9	negative selection	1174487
16869504	16869527	X	+	26627737	RPE1	viability after 9 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.9009527173714214	[872]	[141,151]	-6	hSpCas9	negative selection	1174488
16852746	16852769	X	+	26627737	RPE1	viability after 12 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.1311398081093048	[482]	[196,83]	0	hSpCas9	negative selection	1256798
16853713	16853736	X	+	26627737	RPE1	viability after 12 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.49734543070484344	[569]	[90,126]	-3	hSpCas9	negative selection	1256799
16858754	16858777	X	+	26627737	RPE1	viability after 12 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.14714252552502605	[1045]	[300,321]	1	hSpCas9	negative selection	1256800
16862955	16862978	X	+	26627737	RPE1	viability after 12 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.0681166129632949	[4582]	[612,559]	-6	hSpCas9	negative selection	1256801
16869090	16869113	X	+	26627737	RPE1	viability after 12 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.0011574358323179	[330]	[228,123]	6	hSpCas9	negative selection	1256802
16869504	16869527	X	+	26627737	RPE1	viability after 12 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.40309660671414094	[872]	[172,181]	-3	hSpCas9	negative selection	1256803
16852746	16852769	X	+	26627737	RPE1	viability after 15 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-1.4221532347525887	[482]	[79,22]	-7	hSpCas9	negative selection	1339113
16853713	16853736	X	+	26627737	RPE1	viability after 15 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.1988055441359316	[569]	[56,220]	-1	hSpCas9	negative selection	1339114
16858754	16858777	X	+	26627737	RPE1	viability after 15 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.004301444362204143	[1045]	[421,175]	0	hSpCas9	negative selection	1339115
16862955	16862978	X	+	26627737	RPE1	viability after 15 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.077797006052116	[4582]	[659,569]	-6	hSpCas9	negative selection	1339116
16869090	16869113	X	+	26627737	RPE1	viability after 15 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.1330232673670908	[330]	[297,115]	6	hSpCas9	negative selection	1339117
16869504	16869527	X	+	26627737	RPE1	viability after 15 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.570515271280094	[872]	[177,154]	-4	hSpCas9	negative selection	1339118
16852746	16852769	X	+	26627737	RPE1	viability after 18 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-1.08642303713965	[482]	[57,64]	-6	hSpCas9	negative selection	1421428
16853713	16853736	X	+	26627737	RPE1	viability after 18 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.4028781037050816	[569]	[126,284]	2	hSpCas9	negative selection	1421429
16858754	16858777	X	+	26627737	RPE1	viability after 18 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-1.1614416119352162	[1045]	[131,119]	-6	hSpCas9	negative selection	1421430
16862955	16862978	X	+	26627737	RPE1	viability after 18 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.2510138425864663	[4582]	[625,405]	-6	hSpCas9	negative selection	1421431
16869090	16869113	X	+	26627737	RPE1	viability after 18 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.5073963252930555	[330]	[169,80]	3	hSpCas9	negative selection	1421432
16869504	16869527	X	+	26627737	RPE1	viability after 18 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.5486158195608268	[872]	[133,189]	-3	hSpCas9	negative selection	1421433
16852746	16852769	X	+	26627737	HeLa	viability after 8 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.4100217170367013	[122]	[102,114,6]	4	hSpCas9	negative selection	1503743
16853713	16853736	X	+	26627737	HeLa	viability after 8 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.1908441409558983	[151]	[27,37,144]	1	hSpCas9	negative selection	1503744
16858754	16858777	X	+	26627737	HeLa	viability after 8 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.2848516149721361	[662]	[79,330,262]	-3	hSpCas9	negative selection	1503745
16862955	16862978	X	+	26627737	HeLa	viability after 8 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.1619715159014956	[2108]	[1032,586,882]	-1	hSpCas9	negative selection	1503746
16869090	16869113	X	+	26627737	HeLa	viability after 8 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.6919208435193351	[179]	[179,212,6]	6	hSpCas9	negative selection	1503747
16869504	16869527	X	+	26627737	HeLa	viability after 8 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.03075461556836434	[250]	[106,139,75]	0	hSpCas9	negative selection	1503748
16852746	16852769	X	+	26627737	HeLa	viability after 12 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	1.0805575475002382	[122]	[52,68,202]	7	hSpCas9	negative selection	1586058
16853713	16853736	X	+	26627737	HeLa	viability after 12 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.329690188147519	[151]	[239,63,181]	8	hSpCas9	negative selection	1586059
16858754	16858777	X	+	26627737	HeLa	viability after 12 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.7985326096351021	[662]	[100,156,212]	-6	hSpCas9	negative selection	1586060
16862955	16862978	X	+	26627737	HeLa	viability after 12 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.02833409143401866	[2108]	[942,688,951]	0	hSpCas9	negative selection	1586061
16869090	16869113	X	+	26627737	HeLa	viability after 12 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.9418347064321722	[179]	[242,157,28]	7	hSpCas9	negative selection	1586062
16869504	16869527	X	+	26627737	HeLa	viability after 12 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.05340398865383256	[250]	[108,72,120]	0	hSpCas9	negative selection	1586063
16852746	16852769	X	+	26627737	HeLa	viability after 15 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.4859242577498979	[122]	[72,10,130]	4	hSpCas9	negative selection	1668373
16853713	16853736	X	+	26627737	HeLa	viability after 15 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.2925747196151414	[151]	[105,68,290]	8	hSpCas9	negative selection	1668374
16858754	16858777	X	+	26627737	HeLa	viability after 15 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.46849638186226317	[662]	[272,190,113]	-4	hSpCas9	negative selection	1668375
16862955	16862978	X	+	26627737	HeLa	viability after 15 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.45512111295310276	[2108]	[497,665,723]	-4	hSpCas9	negative selection	1668376
16869090	16869113	X	+	26627737	HeLa	viability after 15 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.8193388720294403	[179]	[135,192,52]	6	hSpCas9	negative selection	1668377
16869504	16869527	X	+	26627737	HeLa	viability after 15 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	0.5243815593578888	[250]	[124,231,78]	4	hSpCas9	negative selection	1668378
16852746	16852769	X	+	26627737	HeLa	viability after 18 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.4202842070439561	[122]	[42,8,130]	3	hSpCas9	negative selection	1750688
16853713	16853736	X	+	26627737	HeLa	viability after 18 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.3031554989313956	[151]	[74,54,290]	8	hSpCas9	negative selection	1750689
16858754	16858777	X	+	26627737	HeLa	viability after 18 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.45297779787998765	[662]	[192,150,113]	-4	hSpCas9	negative selection	1750690
16862955	16862978	X	+	26627737	HeLa	viability after 18 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.4616658027807856	[2108]	[328,550,723]	-4	hSpCas9	negative selection	1750691
16869090	16869113	X	+	26627737	HeLa	viability after 18 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.8014545187973801	[179]	[87,159,52]	6	hSpCas9	negative selection	1750692
16869504	16869527	X	+	26627737	HeLa	viability after 18 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	0.5604999675920748	[250]	[87,195,78]	4	hSpCas9	negative selection	1750693
16852746	16852769	X	+	26627737	HCT116	viability after 6 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.11725832798070368	[338]	[22,76]	0	hSpCas9	negative selection	1833003
16853713	16853736	X	+	26627737	HCT116	viability after 6 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-1.0225056054303807	[568]	[112,5]	-5	hSpCas9	negative selection	1833004
16858754	16858777	X	+	26627737	HCT116	viability after 6 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.1977805551917673	[1053]	[200,183]	1	hSpCas9	negative selection	1833005
16862955	16862978	X	+	26627737	HCT116	viability after 6 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	1.2399673276450547	[2388]	[1976,285]	6	hSpCas9	negative selection	1833006
16869090	16869113	X	+	26627737	HCT116	viability after 6 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.7928042640708015	[325]	[169,43]	4	hSpCas9	negative selection	1833007
16869504	16869527	X	+	26627737	HCT116	viability after 6 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-1.060852345759159	[571]	[84,19]	-6	hSpCas9	negative selection	1833008
16852746	16852769	X	+	26627737	HCT116	viability after 8 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.8103747368791907	[338]	[72,142,102]	-7	hSpCas9	negative selection	1915318
16853713	16853736	X	+	26627737	HCT116	viability after 8 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.6302946071430546	[355]	[92,110,174]	-6	hSpCas9	negative selection	1915319
16858754	16858777	X	+	26627737	HCT116	viability after 8 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.14168802547291898	[458]	[217,191,276]	-1	hSpCas9	negative selection	1915320
16862955	16862978	X	+	26627737	HCT116	viability after 8 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.5354211071511146	[969]	[834,870,620]	5	hSpCas9	negative selection	1915321
16869090	16869113	X	+	26627737	HCT116	viability after 8 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.1956659844298954	[191]	[156,74,131]	2	hSpCas9	negative selection	1915322
16869504	16869527	X	+	26627737	HCT116	viability after 8 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.6656327081234841	[253]	[61,94,106]	-7	hSpCas9	negative selection	1915323
16852746	16852769	X	+	26627737	HCT116	viability after 9 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	0.19615803219096817	[338]	[220,10]	1	hSpCas9	negative selection	1997633
16853713	16853736	X	+	26627737	HCT116	viability after 9 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.5729414402831964	[568]	[182,259]	4	hSpCas9	negative selection	1997634
16858754	16858777	X	+	26627737	HCT116	viability after 9 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.052665512963075756	[1053]	[144,407]	0	hSpCas9	negative selection	1997635
16862955	16862978	X	+	26627737	HCT116	viability after 9 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	1.0649650457125377	[2388]	[1743,1010]	7	hSpCas9	negative selection	1997636
16869090	16869113	X	+	26627737	HCT116	viability after 9 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.7092087732767177	[325]	[186,106]	5	hSpCas9	negative selection	1997637
16869504	16869527	X	+	26627737	HCT116	viability after 9 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.5634680830731219	[571]	[37,154]	-4	hSpCas9	negative selection	1997638
16852746	16852769	X	+	26627737	HCT116	viability after 12 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.8261514014468974	[338]	[60,144,99]	-7	hSpCas9	negative selection	2079948
16853713	16853736	X	+	26627737	HCT116	viability after 12 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.013478919386655214	[355]	[155,200,201]	0	hSpCas9	negative selection	2079949
16858754	16858777	X	+	26627737	HCT116	viability after 12 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.24471036533120916	[458]	[247,213,396]	2	hSpCas9	negative selection	2079950
16862955	16862978	X	+	26627737	HCT116	viability after 12 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.5345401173357924	[969]	[792,806,611]	5	hSpCas9	negative selection	2079951
16869090	16869113	X	+	26627737	HCT116	viability after 12 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.7372177333270342	[191]	[242,125,127]	6	hSpCas9	negative selection	2079952
16869504	16869527	X	+	26627737	HCT116	viability after 12 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.7278664004603317	[253]	[42,117,84]	-7	hSpCas9	negative selection	2079953
16852746	16852769	X	+	26627737	HCT116	viability after 15 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.7267536250094515	[338]	[69,148,127]	-6	hSpCas9	negative selection	2162263
16853713	16853736	X	+	26627737	HCT116	viability after 15 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.6484238602217179	[355]	[72,237,73]	-6	hSpCas9	negative selection	2162264
16858754	16858777	X	+	26627737	HCT116	viability after 15 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.08445725509310964	[458]	[418,201,234]	0	hSpCas9	negative selection	2162265
16862955	16862978	X	+	26627737	HCT116	viability after 15 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.5774337715405076	[969]	[1168,712,654]	5	hSpCas9	negative selection	2162266
16869090	16869113	X	+	26627737	HCT116	viability after 15 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.8941216088925015	[191]	[254,88,275]	7	hSpCas9	negative selection	2162267
16869504	16869527	X	+	26627737	HCT116	viability after 15 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.5107363221082752	[253]	[74,141,86]	-5	hSpCas9	negative selection	2162268
16852746	16852769	X	+	26627737	HCT116	viability after 18 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-1.32085560430292	[338]	[10,94,89]	-8	hSpCas9	negative selection	2244578
16853713	16853736	X	+	26627737	HCT116	viability after 18 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.10100399561205822	[355]	[146,160,173]	-1	hSpCas9	negative selection	2244579
16858754	16858777	X	+	26627737	HCT116	viability after 18 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.062318335937972646	[458]	[197,171,272]	0	hSpCas9	negative selection	2244580
16862955	16862978	X	+	26627737	HCT116	viability after 18 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.4673845677636135	[969]	[725,625,591]	4	hSpCas9	negative selection	2244581
16869090	16869113	X	+	26627737	HCT116	viability after 18 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.9283210223425626	[191]	[187,102,246]	7	hSpCas9	negative selection	2244582
16869504	16869527	X	+	26627737	HCT116	viability after 18 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.1806081731341116	[253]	[52,139,130]	-2	hSpCas9	negative selection	2244583
16863059	16863082	X	-	24336569	HL60	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	0.4607301144865261	[1163]	[3389]	4	hSpCas9	negative selection	2288602
16863092	16863115	X	-	24336569	HL60	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	-0.20329481387016374	[530]	[975]	-2	hSpCas9	negative selection	2288603
16869067	16869090	X	+	24336569	HL60	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	0.680708787322693	[277]	[942]	6	hSpCas9	negative selection	2288604
16869081	16869104	X	+	24336569	HL60	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	-0.33625451236778175	[348]	[584]	-3	hSpCas9	negative selection	2288605
16869090	16869113	X	+	24336569	HL60	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-0.13189352747203648	[654]	[1264]	-1	hSpCas9	negative selection	2288606
16869107	16869130	X	+	24336569	HL60	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.30541943609923594	[303]	[794]	3	hSpCas9	negative selection	2288607
16869114	16869137	X	-	24336569	HL60	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.961882484876224	[323]	[351]	-7	hSpCas9	negative selection	2288608
16869119	16869142	X	+	24336569	HL60	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.04221456042706406	[978]	[2011]	0	hSpCas9	negative selection	2288609
16869133	16869156	X	+	24336569	HL60	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-1.3135066919990632	[349]	[297]	-8	hSpCas9	negative selection	2288610
16869200	16869223	X	-	24336569	HL60	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.5058693045550069	[607]	[1826]	4	hSpCas9	negative selection	2288611
16863059	16863082	X	-	24336569	KBM7	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	0.04379756008392799	[1278]	[3595]	0	hSpCas9	negative selection	2355779
16863092	16863115	X	-	24336569	KBM7	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	0.9773547267804146	[226]	[1218]	8	hSpCas9	negative selection	2355780
16869067	16869090	X	+	24336569	KBM7	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	0.28649811829249705	[299]	[997]	2	hSpCas9	negative selection	2355781
16869081	16869104	X	+	24336569	KBM7	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	1.0943145822803875	[203]	[1187]	8	hSpCas9	negative selection	2355782
16869090	16869113	X	+	24336569	KBM7	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.6458805607906652	[578]	[2470]	6	hSpCas9	negative selection	2355783
16869107	16869130	X	+	24336569	KBM7	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	-0.0798474120483953	[278]	[719]	0	hSpCas9	negative selection	2355784
16869114	16869137	X	-	24336569	KBM7	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	0.40708144028707827	[179]	[650]	4	hSpCas9	negative selection	2355785
16869119	16869142	X	+	24336569	KBM7	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.6173536742244676	[598]	[1064]	-5	hSpCas9	negative selection	2355786
16869133	16869156	X	+	24336569	KBM7	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-1.3624118132862055	[147]	[156]	-7	hSpCas9	negative selection	2355787
16869200	16869223	X	-	24336569	KBM7	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.4141561950114323	[575]	[1178]	-3	hSpCas9	negative selection	2355788
16869956	16869979	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTTTCGCCGGCGCGTGCCGCGG	RBBP7	ENSG00000102054	-0.9476191339325623	[73,8]	[6,0]	-5	dCas9-VP64	positive selection	2409910
16869930	16869953	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAATTGGCGTGCGGAGCAGGGGG	RBBP7	ENSG00000102054	0.00805298054922221	[65,31]	[15,4]	0	dCas9-VP64	positive selection	2409911
16870030	16870053	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCGAGTAAAGAGAGTAAGAGG	RBBP7	ENSG00000102054	1.080811294496897	[33,92]	[27,31]	4	dCas9-VP64	positive selection	2409912
16869956	16869979	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTTTCGCCGGCGCGTGCCGCGG	RBBP7	ENSG00000102054	-0.2932170090600281	[20,79]	[12,12]	-3	dCas9-VP64	positive selection	2505165
16869930	16869953	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAATTGGCGTGCGGAGCAGGGGG	RBBP7	ENSG00000102054	-0.7942705582005556	[148,213]	[23,42]	-7	dCas9-VP64	positive selection	2505166
16870030	16870053	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCGAGTAAAGAGAGTAAGAGG	RBBP7	ENSG00000102054	-0.06526695050012787	[125,16]	[33,10]	0	dCas9-VP64	positive selection	2505167
16869119	16869142	X	+	27260157	DLD1	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.014279909995446	[]	[]	0	hSpCas9	negative selection	2577159
16869845	16869868	X	-	27260157	DLD1	viability	CCGAGGGCTCCGAGCACTTCCGG	RBBP7	ENSG00000102054	0.917967158446207	[]	[]	9	hSpCas9	negative selection	2580588
16869090	16869113	X	+	27260157	DLD1	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	0.959708950494496	[]	[]	9	hSpCas9	negative selection	2582978
16869093	16869116	X	-	27260157	DLD1	viability	GGCCCAGTCTTACCGTTCAGTGG	RBBP7	ENSG00000102054	-1.53773479698271	[]	[]	-8	hSpCas9	negative selection	2583121
16869091	16869114	X	+	27260157	DLD1	viability	AGCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.271059361179165	[]	[]	4	hSpCas9	negative selection	2584901
16869081	16869104	X	+	27260157	DLD1	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	0.016354766103366	[]	[]	0	hSpCas9	negative selection	2604392
16869107	16869130	X	+	27260157	DLD1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.387575809195548	[]	[]	4	hSpCas9	negative selection	2605671
16863059	16863082	X	-	27260157	DLD1	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	0.331355349154043	[]	[]	4	hSpCas9	negative selection	2606712
16869067	16869090	X	+	27260157	DLD1	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	-1.03434906191448	[]	[]	-7	hSpCas9	negative selection	2613432
16863092	16863115	X	-	27260157	DLD1	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	0.702196515590031	[]	[]	8	hSpCas9	negative selection	2616459
16869703	16869726	X	+	27260157	DLD1	viability	CGCGCGCGTAGAAAGAGCCGCGG	RBBP7	ENSG00000102054	-2.09990101913533	[]	[]	-8	hSpCas9	negative selection	2617005
16869133	16869156	X	+	27260157	DLD1	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-0.833360516298904	[]	[]	-6	hSpCas9	negative selection	2618216
16870050	16870073	X	-	27260157	DLD1	viability	GCGAACGACCCGACGCAAGATGG	RBBP7	ENSG00000102054	0.491474074234734	[]	[]	8	hSpCas9	negative selection	2619234
16869622	16869645	X	+	27260157	DLD1	viability	ACGCCCGCCTCGGCAGCCATAGG	RBBP7	ENSG00000102054	0.563912618766563	[]	[]	8	hSpCas9	negative selection	2620474
16869833	16869856	X	-	27260157	DLD1	viability	AGCACTTCCGGAGCCGGGCGCGG	RBBP7	ENSG00000102054	-0.482203946073722	[]	[]	-4	hSpCas9	negative selection	2623484
16869200	16869223	X	-	27260157	DLD1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.418238666881477	[]	[]	-3	hSpCas9	negative selection	2640816
16869502	16869525	X	+	27260157	DLD1	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.187763945574236	[]	[]	-1	hSpCas9	negative selection	2644078
16870041	16870064	X	+	27260157	DLD1	viability	CTTTACTCGCCATCTTGCGTCGG	RBBP7	ENSG00000102054	-0.655644027083169	[]	[]	-5	hSpCas9	negative selection	2645617
16869114	16869137	X	-	27260157	DLD1	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.00391845005902464	[]	[]	0	hSpCas9	negative selection	2647144
16869555	16869578	X	+	27260157	DLD1	viability	CACGTGTAGCAGAAGCCCACAGG	RBBP7	ENSG00000102054	-0.0725669171032194	[]	[]	0	hSpCas9	negative selection	2647663
16869119	16869142	X	+	27260157	HT1080	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.971640204640532	[]	[]	-8	hSpCas9	negative selection	2653289
16869845	16869868	X	-	27260157	HT1080	viability	CCGAGGGCTCCGAGCACTTCCGG	RBBP7	ENSG00000102054	0.0169219585173973	[]	[]	0	hSpCas9	negative selection	2656718
16869090	16869113	X	+	27260157	HT1080	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-0.102449466319268	[]	[]	0	hSpCas9	negative selection	2659108
16869093	16869116	X	-	27260157	HT1080	viability	GGCCCAGTCTTACCGTTCAGTGG	RBBP7	ENSG00000102054	-1.11730550836064	[]	[]	-8	hSpCas9	negative selection	2659251
16869091	16869114	X	+	27260157	HT1080	viability	AGCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	-0.163397705197656	[]	[]	0	hSpCas9	negative selection	2661031
16869081	16869104	X	+	27260157	HT1080	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	-0.706669695212983	[]	[]	-8	hSpCas9	negative selection	2680522
16869107	16869130	X	+	27260157	HT1080	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.123888925452612	[]	[]	1	hSpCas9	negative selection	2681801
16863059	16863082	X	-	27260157	HT1080	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	-0.22116381717263	[]	[]	0	hSpCas9	negative selection	2682842
16869067	16869090	X	+	27260157	HT1080	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	-1.57784546635218	[]	[]	-9	hSpCas9	negative selection	2689562
16863092	16863115	X	-	27260157	HT1080	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	-0.396452485268533	[]	[]	-7	hSpCas9	negative selection	2692589
16869703	16869726	X	+	27260157	HT1080	viability	CGCGCGCGTAGAAAGAGCCGCGG	RBBP7	ENSG00000102054	-1.9483002401566	[]	[]	-9	hSpCas9	negative selection	2693135
16869133	16869156	X	+	27260157	HT1080	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-0.746061147844719	[]	[]	-8	hSpCas9	negative selection	2694346
16870050	16870073	X	-	27260157	HT1080	viability	GCGAACGACCCGACGCAAGATGG	RBBP7	ENSG00000102054	1.06831350455182	[]	[]	8	hSpCas9	negative selection	2695364
16869622	16869645	X	+	27260157	HT1080	viability	ACGCCCGCCTCGGCAGCCATAGG	RBBP7	ENSG00000102054	0.765785168180271	[]	[]	6	hSpCas9	negative selection	2696604
16869833	16869856	X	-	27260157	HT1080	viability	AGCACTTCCGGAGCCGGGCGCGG	RBBP7	ENSG00000102054	0.935006220242283	[]	[]	7	hSpCas9	negative selection	2699614
16869200	16869223	X	-	27260157	HT1080	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.56814753839262	[]	[]	-7	hSpCas9	negative selection	2716946
16869502	16869525	X	+	27260157	HT1080	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.429045542312879	[]	[]	-7	hSpCas9	negative selection	2720208
16870041	16870064	X	+	27260157	HT1080	viability	CTTTACTCGCCATCTTGCGTCGG	RBBP7	ENSG00000102054	-1.3704147673682	[]	[]	-9	hSpCas9	negative selection	2721747
16869114	16869137	X	-	27260157	HT1080	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.868233804029474	[]	[]	-8	hSpCas9	negative selection	2723274
16869555	16869578	X	+	27260157	HT1080	viability	CACGTGTAGCAGAAGCCCACAGG	RBBP7	ENSG00000102054	0.754477776786003	[]	[]	6	hSpCas9	negative selection	2723793
16869119	16869142	X	+	27260157	MKN45	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	0.588450625948741	[]	[]	7	hSpCas9	negative selection	2729419
16869845	16869868	X	-	27260157	MKN45	viability	CCGAGGGCTCCGAGCACTTCCGG	RBBP7	ENSG00000102054	0.685120992962355	[]	[]	7	hSpCas9	negative selection	2732848
16869090	16869113	X	+	27260157	MKN45	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.05287141465075	[]	[]	8	hSpCas9	negative selection	2735238
16869093	16869116	X	-	27260157	MKN45	viability	GGCCCAGTCTTACCGTTCAGTGG	RBBP7	ENSG00000102054	-0.653539745977387	[]	[]	-7	hSpCas9	negative selection	2735381
16869091	16869114	X	+	27260157	MKN45	viability	AGCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.88185245002252	[]	[]	9	hSpCas9	negative selection	2737161
16869081	16869104	X	+	27260157	MKN45	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	1.06488872966391	[]	[]	8	hSpCas9	negative selection	2756652
16869107	16869130	X	+	27260157	MKN45	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	1.05386940045641	[]	[]	8	hSpCas9	negative selection	2757931
16863059	16863082	X	-	27260157	MKN45	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	0.373905834565293	[]	[]	6	hSpCas9	negative selection	2758972
16869067	16869090	X	+	27260157	MKN45	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	-0.0729691495969937	[]	[]	0	hSpCas9	negative selection	2765692
16863092	16863115	X	-	27260157	MKN45	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	0.95516816296088	[]	[]	8	hSpCas9	negative selection	2768719
16869703	16869726	X	+	27260157	MKN45	viability	CGCGCGCGTAGAAAGAGCCGCGG	RBBP7	ENSG00000102054	-3.00365389873115	[]	[]	-9	hSpCas9	negative selection	2769265
16869133	16869156	X	+	27260157	MKN45	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-0.59161090226129	[]	[]	-6	hSpCas9	negative selection	2770476
16870050	16870073	X	-	27260157	MKN45	viability	GCGAACGACCCGACGCAAGATGG	RBBP7	ENSG00000102054	1.5602059491293	[]	[]	9	hSpCas9	negative selection	2771494
16869622	16869645	X	+	27260157	MKN45	viability	ACGCCCGCCTCGGCAGCCATAGG	RBBP7	ENSG00000102054	0.983334221321418	[]	[]	8	hSpCas9	negative selection	2772734
16869833	16869856	X	-	27260157	MKN45	viability	AGCACTTCCGGAGCCGGGCGCGG	RBBP7	ENSG00000102054	0.216319655877745	[]	[]	5	hSpCas9	negative selection	2775744
16869200	16869223	X	-	27260157	MKN45	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.395699342887813	[]	[]	-1	hSpCas9	negative selection	2793076
16869502	16869525	X	+	27260157	MKN45	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.399730041516847	[]	[]	6	hSpCas9	negative selection	2796338
16870041	16870064	X	+	27260157	MKN45	viability	CTTTACTCGCCATCTTGCGTCGG	RBBP7	ENSG00000102054	-0.527328120468295	[]	[]	-6	hSpCas9	negative selection	2797877
16869114	16869137	X	-	27260157	MKN45	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	0.156605938685805	[]	[]	5	hSpCas9	negative selection	2799404
16869555	16869578	X	+	27260157	MKN45	viability	CACGTGTAGCAGAAGCCCACAGG	RBBP7	ENSG00000102054	0.182825576813939	[]	[]	5	hSpCas9	negative selection	2799923
16869119	16869142	X	+	27260157	RKO	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.619090588002626	[]	[]	-7	hSpCas9	negative selection	2805549
16869845	16869868	X	-	27260157	RKO	viability	CCGAGGGCTCCGAGCACTTCCGG	RBBP7	ENSG00000102054	0.997230666580081	[]	[]	9	hSpCas9	negative selection	2808978
16869090	16869113	X	+	27260157	RKO	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.25221686094029	[]	[]	9	hSpCas9	negative selection	2811368
16869093	16869116	X	-	27260157	RKO	viability	GGCCCAGTCTTACCGTTCAGTGG	RBBP7	ENSG00000102054	0.265725326377942	[]	[]	1	hSpCas9	negative selection	2811511
16869091	16869114	X	+	27260157	RKO	viability	AGCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.718628791482681	[]	[]	8	hSpCas9	negative selection	2813291
16869081	16869104	X	+	27260157	RKO	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	-0.0507638667055974	[]	[]	0	hSpCas9	negative selection	2832782
16869107	16869130	X	+	27260157	RKO	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.559627646195673	[]	[]	3	hSpCas9	negative selection	2834061
16863059	16863082	X	-	27260157	RKO	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	0.591735450720997	[]	[]	3	hSpCas9	negative selection	2835102
16869067	16869090	X	+	27260157	RKO	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	-0.158426329932325	[]	[]	-1	hSpCas9	negative selection	2841822
16863092	16863115	X	-	27260157	RKO	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	-0.0195403800859514	[]	[]	0	hSpCas9	negative selection	2844849
16869703	16869726	X	+	27260157	RKO	viability	CGCGCGCGTAGAAAGAGCCGCGG	RBBP7	ENSG00000102054	-2.04573244914427	[]	[]	-9	hSpCas9	negative selection	2845395
16869133	16869156	X	+	27260157	RKO	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-0.0791516098791255	[]	[]	0	hSpCas9	negative selection	2846606
16870050	16870073	X	-	27260157	RKO	viability	GCGAACGACCCGACGCAAGATGG	RBBP7	ENSG00000102054	1.17484737651837	[]	[]	9	hSpCas9	negative selection	2847624
16869622	16869645	X	+	27260157	RKO	viability	ACGCCCGCCTCGGCAGCCATAGG	RBBP7	ENSG00000102054	0.607269358556266	[]	[]	3	hSpCas9	negative selection	2848864
16869833	16869856	X	-	27260157	RKO	viability	AGCACTTCCGGAGCCGGGCGCGG	RBBP7	ENSG00000102054	0.356414987524474	[]	[]	2	hSpCas9	negative selection	2851874
16869200	16869223	X	-	27260157	RKO	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.0537854524552175	[]	[]	0	hSpCas9	negative selection	2869206
16869502	16869525	X	+	27260157	RKO	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.438487841389646	[]	[]	-6	hSpCas9	negative selection	2872468
16870041	16870064	X	+	27260157	RKO	viability	CTTTACTCGCCATCTTGCGTCGG	RBBP7	ENSG00000102054	-0.105601617761139	[]	[]	0	hSpCas9	negative selection	2874007
16869114	16869137	X	-	27260157	RKO	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.651969715799347	[]	[]	-7	hSpCas9	negative selection	2875534
16869555	16869578	X	+	27260157	RKO	viability	CACGTGTAGCAGAAGCCCACAGG	RBBP7	ENSG00000102054	0.278568593012778	[]	[]	1	hSpCas9	negative selection	2876053
16869119	16869142	X	+	27260157	SF268	viability	GAAGAGCATGGGTCATAACCAGG	RBBP7	ENSG00000102054	-0.722621312748824	[]	[]	-5	hSpCas9	negative selection	2881679
16869845	16869868	X	-	27260157	SF268	viability	CCGAGGGCTCCGAGCACTTCCGG	RBBP7	ENSG00000102054	0.760586761259141	[]	[]	8	hSpCas9	negative selection	2885108
16869090	16869113	X	+	27260157	SF268	viability	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	1.14254470421787	[]	[]	9	hSpCas9	negative selection	2887498
16869093	16869116	X	-	27260157	SF268	viability	GGCCCAGTCTTACCGTTCAGTGG	RBBP7	ENSG00000102054	-0.467385327596698	[]	[]	-4	hSpCas9	negative selection	2887641
16869091	16869114	X	+	27260157	SF268	viability	AGCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.23707082769503	[]	[]	9	hSpCas9	negative selection	2889421
16869081	16869104	X	+	27260157	SF268	viability	CACTTCAGGAAGCCACTGAACGG	RBBP7	ENSG00000102054	-0.142738379796649	[]	[]	-1	hSpCas9	negative selection	2908912
16869107	16869130	X	+	27260157	SF268	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.576109842576654	[]	[]	8	hSpCas9	negative selection	2910191
16863059	16863082	X	-	27260157	SF268	viability	GCCCTTCATTGGCTAGTGCTGGG	RBBP7	ENSG00000102054	-0.0626228630063144	[]	[]	0	hSpCas9	negative selection	2911232
16869067	16869090	X	+	27260157	SF268	viability	AACCCTTACTTAGTCACTTCAGG	RBBP7	ENSG00000102054	-1.26933584837086	[]	[]	-7	hSpCas9	negative selection	2917952
16863092	16863115	X	-	27260157	SF268	viability	TCTTTCTTAAACAGACCTGAAGG	RBBP7	ENSG00000102054	0.64473134923628	[]	[]	8	hSpCas9	negative selection	2920979
16869703	16869726	X	+	27260157	SF268	viability	CGCGCGCGTAGAAAGAGCCGCGG	RBBP7	ENSG00000102054	-1.59570436038634	[]	[]	-8	hSpCas9	negative selection	2921525
16869133	16869156	X	+	27260157	SF268	viability	ATAACCAGGTCATATAGAAACGG	RBBP7	ENSG00000102054	-1.15026376359623	[]	[]	-7	hSpCas9	negative selection	2922736
16870050	16870073	X	-	27260157	SF268	viability	GCGAACGACCCGACGCAAGATGG	RBBP7	ENSG00000102054	1.92545926134845	[]	[]	9	hSpCas9	negative selection	2923754
16869622	16869645	X	+	27260157	SF268	viability	ACGCCCGCCTCGGCAGCCATAGG	RBBP7	ENSG00000102054	1.49930633777408	[]	[]	9	hSpCas9	negative selection	2924994
16869833	16869856	X	-	27260157	SF268	viability	AGCACTTCCGGAGCCGGGCGCGG	RBBP7	ENSG00000102054	-0.641693741080557	[]	[]	-5	hSpCas9	negative selection	2928004
16869200	16869223	X	-	27260157	SF268	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	-0.644634292883988	[]	[]	-5	hSpCas9	negative selection	2945336
16869502	16869525	X	+	27260157	SF268	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.661744685982076	[]	[]	8	hSpCas9	negative selection	2948598
16870041	16870064	X	+	27260157	SF268	viability	CTTTACTCGCCATCTTGCGTCGG	RBBP7	ENSG00000102054	-0.492742020599057	[]	[]	-4	hSpCas9	negative selection	2950137
16869114	16869137	X	-	27260157	SF268	viability	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.665398203127613	[]	[]	-5	hSpCas9	negative selection	2951664
16869555	16869578	X	+	27260157	SF268	viability	CACGTGTAGCAGAAGCCCACAGG	RBBP7	ENSG00000102054	0.679571672101586	[]	[]	8	hSpCas9	negative selection	2952183
16869109	16869132	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	-0.3224466534034782	[3,3]	[3,1]	-4	hSpCas9	positive selection	3015885
16862957	16862980	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	0.8627324180825102	[3,3]	[2,8]	9	hSpCas9	positive selection	3015886
16863024	16863047	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.0756924909522993	[3,3]	[4,2]	1	hSpCas9	positive selection	3015887
16869114	16869137	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.5338728193716336	[4,3]	[4,0]	-7	hSpCas9	positive selection	3015888
16869109	16869132	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	0.371494508434166	[3,3]	[2,4]	6	hSpCas9	positive selection	3083743
16862957	16862980	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	0.20145001921264977	[3,3]	[2,2]	3	hSpCas9	positive selection	3083744
16863024	16863047	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.06271513368704887	[3,3]	[3,1]	-1	hSpCas9	positive selection	3083745
16869114	16869137	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.40781142575045737	[4,4]	[4,0]	-6	hSpCas9	positive selection	3083746
16853713	16853736		+	24336571	A375	resistance to PLX after 7 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.041108228504601385	[32,27]	[28,28]	-1	hSpCas9	positive selection	3140012
16853712	16853735		-	24336571	A375	resistance to PLX after 7 days	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	-0.1715529348167777	[50,49]	[45,43]	-5	hSpCas9	positive selection	3140013
16863027	16863050		-	24336571	A375	resistance to PLX after 7 days	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	0.16532987168496116	[32,31]	[38,32]	5	hSpCas9	positive selection	3140015
16863057	16863080		+	24336571	A375	resistance to PLX after 7 days	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.295322760610151	[17,13]	[23,15]	7	hSpCas9	positive selection	3140016
16853713	16853736		+	24336571	A375	resistance to PLX after 14 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.03720762412649736	[33,35]	[18,14]	0	hSpCas9	positive selection	3197805
16853712	16853735		-	24336571	A375	resistance to PLX after 14 days	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	-0.7617530411477713	[57,48]	[13,14]	-8	hSpCas9	positive selection	3197806
16863027	16863050		-	24336571	A375	resistance to PLX after 14 days	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	1.3033259849128325	[27,27]	[28,34]	8	hSpCas9	positive selection	3197808
16863057	16863080		+	24336571	A375	resistance to PLX after 14 days	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.35959833436685973	[13,17]	[8,9]	3	hSpCas9	positive selection	3197809
16853713	16853736		+	24336571	A375	viability after 7 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.30697220252107926	[25]	[32,27]	5	hSpCas9	negative selection	3255598
16853712	16853735		-	24336571	A375	viability after 7 days	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.41158314976670374	[39]	[50,49]	6	hSpCas9	negative selection	3255599
16863027	16863050		-	24336571	A375	viability after 7 days	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	-0.0025801847915774	[33]	[32,31]	0	hSpCas9	negative selection	3255601
16863057	16863080		+	24336571	A375	viability after 7 days	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.18815979822487044	[19]	[17,13]	-3	hSpCas9	negative selection	3255602
16853713	16853736		+	24336571	A375	viability after 14 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.5287043011786221	[25]	[33,35]	6	hSpCas9	negative selection	3313391
16853712	16853735		-	24336571	A375	viability after 14 days	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.5043362479704565	[39]	[57,48]	6	hSpCas9	negative selection	3313392
16863027	16863050		-	24336571	A375	viability after 14 days	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	-0.2138814965477529	[33]	[27,27]	-3	hSpCas9	negative selection	3313394
16863057	16863080		+	24336571	A375	viability after 14 days	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.21310206973760204	[19]	[13,17]	-3	hSpCas9	negative selection	3313395
16852044	16852067	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	-1.7815927778464675	[525,525]	[0,0]	-9	hSpCas9	positive selection	3389148
16852054	16852077	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.6874706031148871	[94,94]	[0,0]	3	hSpCas9	positive selection	3389149
16863057	16863080	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3389150
16869108	16869131	X	+	26780180	HT29	viability (Avana library 4 designs)	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	1.74169037975867	[]	[]	6	hSpCas9	negative selection	3454153
16862957	16862980	X	-	26780180	HT29	viability (Avana library 4 designs)	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	1.12189921749687	[]	[]	4	hSpCas9	negative selection	3454154
16863024	16863047	X	-	26780180	HT29	viability (Avana library 4 designs)	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	2.60537188925515	[]	[]	8	hSpCas9	negative selection	3454155
16869114	16869137	X	-	26780180	HT29	viability (Avana library 4 designs)	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	0.766354291244175	[]	[]	3	hSpCas9	negative selection	3454156
16869108	16869131	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	-4.68308229169997	[]	[]	-5	hSpCas9	negative selection	3551361
16862957	16862980	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	-1.30838006066916	[]	[]	-2	hSpCas9	negative selection	3551362
16863024	16863047	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-8.27291411011369	[]	[]	-7	hSpCas9	negative selection	3551363
16869114	16869137	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-8.22857557153905	[]	[]	-7	hSpCas9	negative selection	3551364
16857655	16857678	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-6.80796799001385	[]	[]	-6	hSpCas9	negative selection	3551365
16858667	16858690	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-7.12104029715	[]	[]	-6	hSpCas9	negative selection	3551366
16869108	16869131	X	+	26780180	A375	viability (Avana lentiGuide)	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	24.059161713615	[]	[]	9	hSpCas9	negative selection	3660020
16862957	16862980	X	-	26780180	A375	viability (Avana lentiGuide)	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	13.8979768917673	[]	[]	7	hSpCas9	negative selection	3660021
16863024	16863047	X	-	26780180	A375	viability (Avana lentiGuide)	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	22.0162130945372	[]	[]	9	hSpCas9	negative selection	3660022
16869114	16869137	X	-	26780180	A375	viability (Avana lentiGuide)	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	16.3514456420799	[]	[]	8	hSpCas9	negative selection	3660023
16857655	16857678	X	-	26780180	A375	viability (Avana lentiGuide)	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	36.8540898010506	[]	[]	9	hSpCas9	negative selection	3660024
16858667	16858690	X	+	26780180	A375	viability (Avana lentiGuide)	ATTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	18.0613757047639	[]	[]	8	hSpCas9	negative selection	3660025
16869108	16869131	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	-0.1731017849386869	[4]	[3,4]	-3	hSpCas9	positive selection	3768627
16862957	16862980	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	0.0852885663267107	[4]	[4,5]	2	hSpCas9	positive selection	3768628
16863024	16863047	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.6602060068749521	[5]	[3,2]	-7	hSpCas9	positive selection	3768629
16869114	16869137	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.4906551324831852	[5]	[4,3]	-6	hSpCas9	positive selection	3768630
16857655	16857678	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.35173103219203106	[6]	[4,4]	-5	hSpCas9	positive selection	3768631
16858667	16858690	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-0.3555731884864898	[6]	[3,5]	-5	hSpCas9	positive selection	3768632
16869108	16869131	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGGCCACTGAAGAGCATGGG	RBBP7	ENSG00000102054	-0.21947979150831234	[5]	[4,3]	-3	hSpCas9	positive selection	3877234
16862957	16862980	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCATTGTGACAGTGACAAGGG	RBBP7	ENSG00000102054	-0.9733729110693505	[5]	[1,1]	-8	hSpCas9	positive selection	3877235
16863024	16863047	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-1.2226986304095824	[5]	[0,2]	-9	hSpCas9	positive selection	3877236
16869114	16869137	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGACCCATGCTCTTCAGTGG	RBBP7	ENSG00000102054	-0.5983879030178492	[6]	[2,3]	-6	hSpCas9	positive selection	3877237
16857655	16857678	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.6206882336074441	[6]	[2,4]	-7	hSpCas9	positive selection	3877238
16858667	16858690	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-0.4459343134651709	[4]	[3,1]	-5	hSpCas9	positive selection	3877239
16852044	16852067	X	+	26780180	A375	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	2.06670042038627	[]	[]	9	hSpCas9	negative selection	3987657
16869502	16869525	X	+	26780180	A375	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	1.64746975271797	[]	[]	8	hSpCas9	negative selection	3987658
16869511	16869534	X	-	26780180	A375	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	1.43549341798706	[]	[]	8	hSpCas9	negative selection	3987659
16852054	16852077	X	-	26780180	A375	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	1.35896291956402	[]	[]	7	hSpCas9	negative selection	3987660
16853712	16853735	X	-	26780180	A375	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.404902140401283	[]	[]	1	hSpCas9	negative selection	3987661
16863057	16863080	X	+	26780180	A375	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	1.36895714302091	[]	[]	7	hSpCas9	negative selection	3987662
16852044	16852067	X	+	26780180	HT29	viability (GeCKOv2 library)	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.978630832168534	[]	[]	4	hSpCas9	negative selection	4095623
16869502	16869525	X	+	26780180	HT29	viability (GeCKOv2 library)	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	1.37166109854422	[]	[]	7	hSpCas9	negative selection	4095624
16869511	16869534	X	-	26780180	HT29	viability (GeCKOv2 library)	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.701890690602319	[]	[]	2	hSpCas9	negative selection	4095625
16852054	16852077	X	-	26780180	HT29	viability (GeCKOv2 library)	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.939001810137323	[]	[]	4	hSpCas9	negative selection	4095626
16853712	16853735	X	-	26780180	HT29	viability (GeCKOv2 library)	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.224338290176679	[]	[]	0	hSpCas9	negative selection	4095627
16863057	16863080	X	+	26780180	HT29	viability (GeCKOv2 library)	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	1.47372781480589	[]	[]	7	hSpCas9	negative selection	4095628
16853713	16853736	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.2456240861627571	[4]	[3,3]	6	hSpCas9	positive selection	4165387
16853712	16853735	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.13873157050288654	[5]	[4,3]	3	hSpCas9	positive selection	4165388
16863027	16863050	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	0.13799799336639257	[5]	[2,4]	3	hSpCas9	positive selection	4165390
16863057	16863080	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.14449196623083266	[4]	[1,3]	-3	hSpCas9	positive selection	4165391
16853713	16853736	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.6706691878648512	[4]	[0,1,2,3]	4	hSpCas9	positive selection	4229409
16853712	16853735	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.86813529051561	[5]	[5,3,4,4]	6	hSpCas9	positive selection	4229410
16863027	16863050	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCTGATGAGCAGAATCATCTGG	RBBP7	ENSG00000102054	-0.19862124529923678	[5]	[3,2,2,0]	-3	hSpCas9	positive selection	4229412
16863057	16863080	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.727309196959195	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4229413
16869502	16869525	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.04063745836273808	[4]	[3,2]	-1	hSpCas9	positive selection	4294068
16869511	16869534	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.11890278380286645	[4]	[3,3]	2	hSpCas9	positive selection	4294069
16853712	16853735	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.28218532944672914	[3]	[4,2]	5	hSpCas9	positive selection	4294070
16852044	16852067	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	-0.15361038383985823	[4]	[4,1]	-3	hSpCas9	positive selection	4358324
16852054	16852077	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.25029350023333935	[1]	[1,0]	-5	hSpCas9	positive selection	4358325
16863057	16863080	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.3387133868973741	[2]	[1,0]	-6	hSpCas9	positive selection	4358326
16869092	16869114	X	+	27760321	OCIAML3	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.6060650446210623	[474,388]	[894,1190]	9	hSpCas9	negative selection	4433435
16857668	16857690	X	+	27760321	OCIAML3	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.7972354022301443	[357,297]	[350,564]	8	hSpCas9	negative selection	4433436
16858668	16858690	X	+	27760321	OCIAML3	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.638903326396099	[139,95]	[98,197]	7	hSpCas9	negative selection	4433437
16858755	16858777	X	+	27760321	OCIAML3	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.10240715056673538	[658,471]	[363,607]	1	hSpCas9	negative selection	4433438
16858786	16858808	X	-	27760321	OCIAML3	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	0.5037501910071849	[41,46]	[47,51]	6	hSpCas9	negative selection	4433439
16869092	16869114	X	+	27760321	OCIAML2	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.9293365709367039	[474,388]	[537,825]	9	hSpCas9	negative selection	4516898
16857668	16857690	X	+	27760321	OCIAML2	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.41579542347010046	[357,297]	[282,443]	5	hSpCas9	negative selection	4516899
16858668	16858690	X	+	27760321	OCIAML2	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-0.12060159456310204	[139,95]	[81,92]	-1	hSpCas9	negative selection	4516900
16858755	16858777	X	+	27760321	OCIAML2	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.2966228728980124	[658,471]	[414,741]	4	hSpCas9	negative selection	4516901
16858786	16858808	X	-	27760321	OCIAML2	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	1.3874958617746582	[41,46]	[84,107]	9	hSpCas9	negative selection	4516902
16869092	16869114	X	+	27760321	MV411	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	2.187685637707142	[474,388]	[1522,945]	9	hSpCas9	negative selection	4600361
16857668	16857690	X	+	27760321	MV411	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.7963618956910445	[357,297]	[277,518]	6	hSpCas9	negative selection	4600362
16858668	16858690	X	+	27760321	MV411	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	1.2042354144465628	[139,95]	[12,423]	8	hSpCas9	negative selection	4600363
16858755	16858777	X	+	27760321	MV411	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	1.0065259076211095	[658,471]	[1004,346]	7	hSpCas9	negative selection	4600364
16858786	16858808	X	-	27760321	MV411	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	2.6832475800544997	[41,46]	[315,0]	9	hSpCas9	negative selection	4600365
16869092	16869114	X	+	27760321	HL60	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.1631567987703469	[474,388]	[449,332]	2	hSpCas9	negative selection	4683824
16857668	16857690	X	+	27760321	HL60	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	-0.5603913862747256	[357,297]	[194,165]	-6	hSpCas9	negative selection	4683825
16858668	16858690	X	+	27760321	HL60	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.719347632506097	[139,95]	[149,163]	8	hSpCas9	negative selection	4683826
16858755	16858777	X	+	27760321	HL60	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.5689225556900013	[658,471]	[568,793]	6	hSpCas9	negative selection	4683827
16858786	16858808	X	-	27760321	HL60	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-1.3610052081541761	[41,46]	[22,4]	-8	hSpCas9	negative selection	4683828
16869092	16869114	X	+	27760321	HT1080	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	-6.142061937690481	[388,303]	[0,2]	-9	hSpCas9	negative selection	4767287
16857668	16857690	X	+	27760321	HT1080	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	-0.35060034948962865	[297,232]	[60,106]	-2	hSpCas9	negative selection	4767288
16858668	16858690	X	+	27760321	HT1080	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.8603365107880143	[95,74]	[68,53]	4	hSpCas9	negative selection	4767289
16858755	16858777	X	+	27760321	HT1080	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-2.8075280024888594	[471,368]	[32,13]	-7	hSpCas9	negative selection	4767290
16858786	16858808	X	-	27760321	HT1080	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	1.7022205276282918	[46,36]	[74,31]	8	hSpCas9	negative selection	4767291
16869092	16869114	X	+	27760321	HT29	viability after 7 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.8995736149247923	[388,303]	[912,793,797]	9	hSpCas9	negative selection	4850750
16857668	16857690	X	+	27760321	HT29	viability after 7 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.15035833289275136	[297,232]	[374,394,365]	2	hSpCas9	negative selection	4850751
16858668	16858690	X	+	27760321	HT29	viability after 7 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.7734730865414232	[95,74]	[255,122,193]	9	hSpCas9	negative selection	4850752
16858755	16858777	X	+	27760321	HT29	viability after 7 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.6090982624723162	[471,368]	[839,804,829]	8	hSpCas9	negative selection	4850753
16858786	16858808	X	-	27760321	HT29	viability after 7 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-2.657489457099439	[46,36]	[2,16,4]	-9	hSpCas9	negative selection	4850754
16869092	16869114	X	+	27760321	HT29	viability after 25 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.1511212203778867	[388,303]	[667,1072,912]	9	hSpCas9	negative selection	4934213
16857668	16857690	X	+	27760321	HT29	viability after 25 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	-0.39917136819331395	[297,232]	[89,195,433]	-4	hSpCas9	negative selection	4934214
16858668	16858690	X	+	27760321	HT29	viability after 25 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-0.8274730745096517	[95,74]	[64,39,59]	-6	hSpCas9	negative selection	4934215
16858755	16858777	X	+	27760321	HT29	viability after 25 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.3700493004466705	[471,368]	[609,486,782]	4	hSpCas9	negative selection	4934216
16858786	16858808	X	-	27760321	HT29	viability after 25 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-3.0945193908180633	[46,36]	[3,6,5]	-8	hSpCas9	negative selection	4934217
16869092	16869114	X	+	27760321	HT29	viability after 22 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.1797215295378176	[388,303]	[968,1136,611]	9	hSpCas9	negative selection	5017676
16857668	16857690	X	+	27760321	HT29	viability after 22 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	-0.7452745093795232	[297,232]	[142,165,241]	-6	hSpCas9	negative selection	5017677
16858668	16858690	X	+	27760321	HT29	viability after 22 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	-0.2991481325630474	[95,74]	[136,71,29]	-3	hSpCas9	negative selection	5017678
16858755	16858777	X	+	27760321	HT29	viability after 22 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.31716698491160145	[471,368]	[780,463,566]	3	hSpCas9	negative selection	5017679
16858786	16858808	X	-	27760321	HT29	viability after 22 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-1.9090538687602985	[46,36]	[3,26,7]	-8	hSpCas9	negative selection	5017680
16869092	16869114	X	+	27760321	HT29	viability after 19 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.049881856132623	[388,303]	[929,816,728]	9	hSpCas9	negative selection	5101139
16857668	16857690	X	+	27760321	HT29	viability after 19 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.38567108211901835	[297,232]	[301,586,294]	4	hSpCas9	negative selection	5101140
16858668	16858690	X	+	27760321	HT29	viability after 19 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.5237219056684335	[95,74]	[229,139,63]	5	hSpCas9	negative selection	5101141
16858755	16858777	X	+	27760321	HT29	viability after 19 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.19553370698001699	[471,368]	[772,693,220]	1	hSpCas9	negative selection	5101142
16858786	16858808	X	-	27760321	HT29	viability after 19 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-1.7223427939082958	[46,36]	[2,38,0]	-7	hSpCas9	negative selection	5101143
16869092	16869114	X	+	27760321	HT29	viability after 16 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.8340346146281183	[388,303]	[865,568,657]	8	hSpCas9	negative selection	5184602
16857668	16857690	X	+	27760321	HT29	viability after 16 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.532981363522033	[297,232]	[267,627,372]	6	hSpCas9	negative selection	5184603
16858668	16858690	X	+	27760321	HT29	viability after 16 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.021364479405185488	[95,74]	[117,105,68]	0	hSpCas9	negative selection	5184604
16858755	16858777	X	+	27760321	HT29	viability after 16 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.3786548520262424	[471,368]	[792,388,675]	4	hSpCas9	negative selection	5184605
16858786	16858808	X	-	27760321	HT29	viability after 16 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-1.4772748685936463	[46,36]	[26,1,22]	-8	hSpCas9	negative selection	5184606
16869092	16869114	X	+	27760321	HT29	viability after 13 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.6754156063445058	[388,303]	[480,660,775]	8	hSpCas9	negative selection	5268065
16857668	16857690	X	+	27760321	HT29	viability after 13 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	-0.4979409263004814	[297,232]	[212,182,255]	-5	hSpCas9	negative selection	5268066
16858668	16858690	X	+	27760321	HT29	viability after 13 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.5997711012621565	[95,74]	[85,229,135]	7	hSpCas9	negative selection	5268067
16858755	16858777	X	+	27760321	HT29	viability after 13 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.4254977258961783	[471,368]	[519,604,829]	5	hSpCas9	negative selection	5268068
16858786	16858808	X	-	27760321	HT29	viability after 13 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-0.38307284677569076	[46,36]	[25,62,23]	-4	hSpCas9	negative selection	5268069
16869092	16869114	X	+	27760321	HT29	viability after 10 days	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	0.8660036376133952	[388,303]	[852,647,858]	9	hSpCas9	negative selection	5351528
16857668	16857690	X	+	27760321	HT29	viability after 10 days	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	0.2664702576430743	[297,232]	[434,416,345]	3	hSpCas9	negative selection	5351529
16858668	16858690	X	+	27760321	HT29	viability after 10 days	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	0.06185223164697229	[95,74]	[168,99,65]	0	hSpCas9	negative selection	5351530
16858755	16858777	X	+	27760321	HT29	viability after 10 days	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.5578902826691942	[471,368]	[965,610,737]	7	hSpCas9	negative selection	5351531
16858786	16858808	X	-	27760321	HT29	viability after 10 days	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	-0.993032780976379	[46,36]	[5,73,0]	-8	hSpCas9	negative selection	5351532
16869092	16869114	X	+	27760321	MOLM13	viability	GCCACTGAACGGTAAGACTGGG	RBBP7	ENSG00000102054	1.366169728509055	[474,388]	[843,438]	8	hSpCas9	negative selection	5434991
16857668	16857690	X	+	27760321	MOLM13	viability	GACCTCTTAATCTGAGATCAGG	RBBP7	ENSG00000102054	1.349357859194294	[357,297]	[374,549]	8	hSpCas9	negative selection	5434992
16858668	16858690	X	+	27760321	MOLM13	viability	TTACATACCTGGTTTAGCAGGG	RBBP7	ENSG00000102054	1.1850057213885985	[139,95]	[121,172]	8	hSpCas9	negative selection	5434993
16858755	16858777	X	+	27760321	MOLM13	viability	CTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	0.31586376346713857	[658,471]	[472,324]	2	hSpCas9	negative selection	5434994
16858786	16858808	X	-	27760321	MOLM13	viability	AAATTAAAATCAATCACGAAGG	RBBP7	ENSG00000102054	0.07116029093741982	[41,46]	[11,38]	0	hSpCas9	negative selection	5434995
16870349	16870372	X	+	27661255	K562	viability	GCCCTGGGAAAAGTGAGAGGAGG	RBBP7	ENSG00000102054	0.15764627612766327	[682,726]	[681,580]	5	dCas9-KRAB	negative selection	5506430
16869892	16869915	X	-	27661255	K562	viability	GACTGGGCGCGCGCCTCGAGGGG	RBBP7	ENSG00000102054	0.16191665151955625	[1192,980]	[1010,943]	5	dCas9-KRAB	negative selection	5506431
16870135	16870158	X	-	27661255	K562	viability	GAGTGTGACGCGCTTGGGAAAGG	RBBP7	ENSG00000102054	0.22140846648795431	[1371,1644]	[1443,1362]	7	dCas9-KRAB	negative selection	5506432
16870249	16870272	X	-	27661255	K562	viability	GAGAAGAGCGCCTCAGACCTCGG	RBBP7	ENSG00000102054	0.24660744853054212	[852,999]	[1016,754]	8	dCas9-KRAB	negative selection	5506433
16869502	16869525	X	+	27260156	BXPC3	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.15156153696025654	[1158]	[1093,1104,1372,1915]	3	hSpCas9	negative selection	5566528
16869511	16869534	X	-	27260156	BXPC3	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.33050625604239414	[1269]	[1577,1649,1685,1777]	7	hSpCas9	negative selection	5566529
16853712	16853735	X	-	27260156	BXPC3	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.31699608634196974	[926]	[1110,1185,1306,1233]	7	hSpCas9	negative selection	5566530
16852044	16852067	X	+	27260156	BXPC3	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.21862426374324428	[1146]	[1296,1295,1459,1556]	5	hSpCas9	negative selection	5630784
16852054	16852077	X	-	27260156	BXPC3	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.5318960257158678	[194]	[273,197,332,392]	9	hSpCas9	negative selection	5630785
16863057	16863080	X	+	27260156	BXPC3	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.04277598551581374	[277]	[245,301,331,324]	0	hSpCas9	negative selection	5630786
16869502	16869525	X	+	27260156	A673	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.0158143938620805	[1158]	[1556,1238,1333,1523]	0	hSpCas9	negative selection	5687779
16869511	16869534	X	-	27260156	A673	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.13055958442324833	[1269]	[1795,1610,1639,1641]	3	hSpCas9	negative selection	5687780
16853712	16853735	X	-	27260156	A673	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3633089810311848	[926]	[1470,1220,1548,1495]	8	hSpCas9	negative selection	5687781
16852044	16852067	X	+	27260156	A673	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.10361946924006848	[1146]	[1692,1450,1377,1416]	2	hSpCas9	negative selection	5752035
16852054	16852077	X	-	27260156	A673	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.4474970982250245	[194]	[295,265,313,403]	8	hSpCas9	negative selection	5752036
16863057	16863080	X	+	27260156	A673	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.191623879353349	[277]	[439,349,402,335]	4	hSpCas9	negative selection	5752037
16869502	16869525	X	+	27260156	A375	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.19063866462551315	[1158]	[1001,1965,1721,1538]	2	hSpCas9	negative selection	5809030
16869511	16869534	X	-	27260156	A375	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.1429242604469112	[1269]	[1470,2285,1397,1495]	2	hSpCas9	negative selection	5809031
16853712	16853735	X	-	27260156	A375	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.14738835018465302	[926]	[1260,1502,993,1089]	2	hSpCas9	negative selection	5809032
16852044	16852067	X	+	27260156	A375	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.00350240906597743	[1146]	[1582,1460,1203,1158]	0	hSpCas9	negative selection	5873286
16852054	16852077	X	-	27260156	A375	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-1.140425557300875	[194]	[116,89,108,95]	-8	hSpCas9	negative selection	5873287
16863057	16863080	X	+	27260156	A375	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-1.25265661531236	[277]	[141,189,110,111]	-8	hSpCas9	negative selection	5873288
16869502	16869525	X	+	27260156	COLO741	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.18182753589340117	[1158]	[1799,1558,1685]	4	hSpCas9	negative selection	5930281
16869511	16869534	X	-	27260156	COLO741	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.1298596614929035	[1269]	[1832,1741,1753]	2	hSpCas9	negative selection	5930282
16853712	16853735	X	-	27260156	COLO741	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.24318749724481703	[926]	[1601,1366,1260]	5	hSpCas9	negative selection	5930283
16852044	16852067	X	+	27260156	COLO741	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.04915763816294927	[1146]	[1795,1176,1589]	1	hSpCas9	negative selection	5994537
16852054	16852077	X	-	27260156	COLO741	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.41666123617230466	[194]	[360,314,323]	8	hSpCas9	negative selection	5994538
16863057	16863080	X	+	27260156	COLO741	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.06442385631314773	[277]	[475,370,281]	1	hSpCas9	negative selection	5994539
16869502	16869525	X	+	27260156	CAL120	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.07617626157402468	[1158]	[2015,1307,1314]	1	hSpCas9	negative selection	6051532
16869511	16869534	X	-	27260156	CAL120	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.04428831295382918	[1269]	[1870,1392,1659]	0	hSpCas9	negative selection	6051533
16853712	16853735	X	-	27260156	CAL120	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.43860301567484716	[926]	[1896,1294,1547]	6	hSpCas9	negative selection	6051534
16852044	16852067	X	+	27260156	CAL120	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.23164271794331048	[1146]	[2152,1559,1390]	3	hSpCas9	negative selection	6115788
16852054	16852077	X	-	27260156	CAL120	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.33956079194363475	[194]	[214,131,230]	-5	hSpCas9	negative selection	6115789
16863057	16863080	X	+	27260156	CAL120	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.026381872877544787	[277]	[248,235,516]	0	hSpCas9	negative selection	6115790
16869502	16869525	X	+	27260156	CADOES1	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.038158497441434625	[1158]	[855,1139,1073,1132]	0	hSpCas9	negative selection	6172783
16869511	16869534	X	-	27260156	CADOES1	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.10292650646401347	[1269]	[1319,1482,1141,1123]	1	hSpCas9	negative selection	6172784
16853712	16853735	X	-	27260156	CADOES1	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.5468850915149369	[926]	[1390,1189,1114,1344]	8	hSpCas9	negative selection	6172785
16852044	16852067	X	+	27260156	CADOES1	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.418476508659801	[1146]	[1203,1555,1259,1693]	7	hSpCas9	negative selection	6237039
16852054	16852077	X	-	27260156	CADOES1	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.37985685935526636	[194]	[125,313,201,304]	6	hSpCas9	negative selection	6237040
16863057	16863080	X	+	27260156	CADOES1	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.5827974094992286	[277]	[417,384,356,388]	8	hSpCas9	negative selection	6237041
16869502	16869525	X	+	27260156	EWS502	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.0762321510822066	[1158]	[1178,1348,1240,1422]	1	hSpCas9	negative selection	6294034
16869511	16869534	X	-	27260156	EWS502	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.008800811631228589	[1269]	[1169,1241,1457,1582]	0	hSpCas9	negative selection	6294035
16853712	16853735	X	-	27260156	EWS502	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.6082222006167147	[926]	[1492,1436,1506,1550]	9	hSpCas9	negative selection	6294036
16852044	16852067	X	+	27260156	EWS502	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.32627790171746884	[1146]	[1239,1726,1274,1893]	6	hSpCas9	negative selection	6358290
16852054	16852077	X	-	27260156	EWS502	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.39174284704868867	[194]	[210,266,394,214]	7	hSpCas9	negative selection	6358291
16863057	16863080	X	+	27260156	EWS502	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.09394858849649768	[277]	[303,252,264,277]	-2	hSpCas9	negative selection	6358292
16869502	16869525	X	+	27260156	EW8	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.2583348337239817	[1158]	[1182,1163,904,1281]	5	hSpCas9	negative selection	6415285
16869511	16869534	X	-	27260156	EW8	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.29612504894272296	[1269]	[1359,1408,964,1378]	5	hSpCas9	negative selection	6415286
16853712	16853735	X	-	27260156	EW8	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.6436144856624167	[926]	[1252,997,1135,1317]	9	hSpCas9	negative selection	6415287
16852044	16852067	X	+	27260156	EW8	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.32598020668090455	[1146]	[1392,994,1127,1171]	6	hSpCas9	negative selection	6479541
16852054	16852077	X	-	27260156	EW8	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.07320827326308676	[194]	[137,222,188,107]	1	hSpCas9	negative selection	6479542
16863057	16863080	X	+	27260156	EW8	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.24041600879437053	[277]	[225,182,329,308]	4	hSpCas9	negative selection	6479543
16869502	16869525	X	+	27260156	CORL105	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.2071638072415498	[1158]	[1890,1442,1883,1111]	4	hSpCas9	negative selection	6536536
16869511	16869534	X	-	27260156	CORL105	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.26966076563910457	[1269]	[1602,1620,2291,1727]	5	hSpCas9	negative selection	6536537
16853712	16853735	X	-	27260156	CORL105	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.22488842438469325	[926]	[1320,1274,1301,1181]	4	hSpCas9	negative selection	6536538
16852044	16852067	X	+	27260156	CORL105	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.0272077677811724	[1146]	[1256,1217,1668,1374]	0	hSpCas9	negative selection	6600792
16852054	16852077	X	-	27260156	CORL105	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.3821304250616946	[194]	[332,288,325,247]	7	hSpCas9	negative selection	6600793
16863057	16863080	X	+	27260156	CORL105	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.13693417430167132	[277]	[311,255,600,300]	2	hSpCas9	negative selection	6600794
16869502	16869525	X	+	27260156	HS294T	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.21136798662429546	[1158]	[465,497,583,533]	3	hSpCas9	negative selection	6657787
16869511	16869534	X	-	27260156	HS294T	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.3073213389224321	[1269]	[551,634,522,745]	4	hSpCas9	negative selection	6657788
16853712	16853735	X	-	27260156	HS294T	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.29363177556648445	[926]	[387,442,448,488]	4	hSpCas9	negative selection	6657789
16852044	16852067	X	+	27260156	HS294T	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	-0.038720304930866645	[1146]	[490,410,368,452]	0	hSpCas9	negative selection	6722043
16852054	16852077	X	-	27260156	HS294T	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.23115574201177314	[194]	[54,56,50,100]	-3	hSpCas9	negative selection	6722044
16863057	16863080	X	+	27260156	HS294T	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.10681492494844458	[277]	[139,76,82,94]	-1	hSpCas9	negative selection	6722045
16869502	16869525	X	+	27260156	HCC44	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.13735295875881248	[1158]	[1524,987,1664,1679]	2	hSpCas9	negative selection	6779038
16869511	16869534	X	-	27260156	HCC44	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.12165649394187428	[1269]	[1808,1488,1617,1370]	2	hSpCas9	negative selection	6779039
16853712	16853735	X	-	27260156	HCC44	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.49354166031525726	[926]	[1500,1094,1456,1878]	7	hSpCas9	negative selection	6779040
16852044	16852067	X	+	27260156	HCC44	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.2907109318778065	[1146]	[1417,1616,1786,1528]	5	hSpCas9	negative selection	6843294
16852054	16852077	X	-	27260156	HCC44	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.24056583326260905	[194]	[241,223,176,102]	-4	hSpCas9	negative selection	6843295
16863057	16863080	X	+	27260156	HCC44	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.24305029152103752	[277]	[181,286,334,257]	-4	hSpCas9	negative selection	6843296
16869502	16869525	X	+	27260156	G402	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.043476612490664035	[1158]	[1923,1983,1102,936]	0	hSpCas9	negative selection	6900289
16869511	16869534	X	-	27260156	G402	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.03095352827512521	[1269]	[1373,1320,1686,1640]	0	hSpCas9	negative selection	6900290
16853712	16853735	X	-	27260156	G402	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.7564776941741217	[926]	[2296,1670,1588,2110]	8	hSpCas9	negative selection	6900291
16852044	16852067	X	+	27260156	G402	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.451447256136821	[1146]	[2266,2024,1770,1654]	5	hSpCas9	negative selection	6964545
16852054	16852077	X	-	27260156	G402	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.6736824016451168	[194]	[105,439,327,595]	8	hSpCas9	negative selection	6964546
16863057	16863080	X	+	27260156	G402	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.06992883597168331	[277]	[270,152,474,492]	0	hSpCas9	negative selection	6964547
16869502	16869525	X	+	27260156	L33	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.13507917971080796	[1158]	[999,384,783,1036]	-3	hSpCas9	negative selection	7021540
16869511	16869534	X	-	27260156	L33	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.17744952135497782	[1269]	[1370,632,788,1572]	4	hSpCas9	negative selection	7021541
16853712	16853735	X	-	27260156	L33	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.28532291369559026	[926]	[1268,441,626,1168]	6	hSpCas9	negative selection	7021542
16852044	16852067	X	+	27260156	L33	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.06662752306815767	[1146]	[1252,434,838,1154]	1	hSpCas9	negative selection	7085796
16852054	16852077	X	-	27260156	L33	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.27016904148516885	[194]	[246,105,125,233]	6	hSpCas9	negative selection	7085797
16863057	16863080	X	+	27260156	L33	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.05540143720780821	[277]	[265,129,116,299]	-1	hSpCas9	negative selection	7085798
16869502	16869525	X	+	27260156	K562	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.2836151873236077	[1158]	[1431,992,1329,1248]	3	hSpCas9	negative selection	7142791
16869511	16869534	X	-	27260156	K562	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.3028453636660622	[1269]	[2049,1333,1093,1155]	4	hSpCas9	negative selection	7142792
16853712	16853735	X	-	27260156	K562	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.8386953102929015	[926]	[1919,1313,1671,1050]	9	hSpCas9	negative selection	7142793
16852044	16852067	X	+	27260156	K562	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.48539024876166326	[1146]	[1381,1801,1608,970]	6	hSpCas9	negative selection	7207047
16852054	16852077	X	-	27260156	K562	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	1.2188914376994844	[194]	[483,309,213,581]	9	hSpCas9	negative selection	7207048
16863057	16863080	X	+	27260156	K562	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.4418627981231547	[277]	[501,164,277,391]	5	hSpCas9	negative selection	7207049
16869502	16869525	X	+	27260156	HT29	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.03791247815997045	[1158]	[1638,1684,1341,1177]	0	hSpCas9	negative selection	7264042
16869511	16869534	X	-	27260156	HT29	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.012475754235399705	[1269]	[2080,1251,1604,1322]	0	hSpCas9	negative selection	7264043
16853712	16853735	X	-	27260156	HT29	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.33649061702020744	[926]	[1445,1433,1471,1341]	6	hSpCas9	negative selection	7264044
16852044	16852067	X	+	27260156	HT29	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.1763027599472371	[1146]	[1736,1795,1697,1144]	3	hSpCas9	negative selection	7328298
16852054	16852077	X	-	27260156	HT29	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.2269934665165929	[194]	[211,304,354,237]	4	hSpCas9	negative selection	7328299
16863057	16863080	X	+	27260156	HT29	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.03943302748468369	[277]	[176,421,334,434]	0	hSpCas9	negative selection	7328300
16869502	16869525	X	+	27260156	MHHES1	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.08411766458326442	[1158]	[1658,1679,1313,1002]	1	hSpCas9	negative selection	7385293
16869511	16869534	X	-	27260156	MHHES1	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.2810536239581316	[1269]	[1747,1955,1662,1599]	5	hSpCas9	negative selection	7385294
16853712	16853735	X	-	27260156	MHHES1	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.31675854264134673	[926]	[1234,1442,1410,1129]	6	hSpCas9	negative selection	7385295
16852044	16852067	X	+	27260156	MHHES1	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.22019836491941103	[1146]	[1537,1808,1494,1239]	4	hSpCas9	negative selection	7449549
16852054	16852077	X	-	27260156	MHHES1	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.2378311766275525	[194]	[197,359,283,203]	4	hSpCas9	negative selection	7449550
16863057	16863080	X	+	27260156	MHHES1	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.38459261280534246	[277]	[465,294,465,396]	7	hSpCas9	negative selection	7449551
16869502	16869525	X	+	27260156	MEWO	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.06105687234150747	[1158]	[1318,1070,1039]	1	hSpCas9	negative selection	7506544
16869511	16869534	X	-	27260156	MEWO	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.10163867440036967	[1269]	[1461,994,1404]	2	hSpCas9	negative selection	7506545
16853712	16853735	X	-	27260156	MEWO	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.14550789718465384	[926]	[1110,974,820]	3	hSpCas9	negative selection	7506546
16852044	16852067	X	+	27260156	MEWO	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.1274332244072225	[1146]	[1508,1080,991]	3	hSpCas9	negative selection	7570800
16852054	16852077	X	-	27260156	MEWO	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.22347810534743662	[194]	[274,205,169]	5	hSpCas9	negative selection	7570801
16863057	16863080	X	+	27260156	MEWO	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.47075177342073604	[277]	[202,177,184]	-7	hSpCas9	negative selection	7570802
16869502	16869525	X	+	27260156	LNCAPCLONEFGC	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.19438257725658836	[1158]	[1191,1054,1542,1074]	3	hSpCas9	negative selection	7627795
16869511	16869534	X	-	27260156	LNCAPCLONEFGC	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.364915109414949	[1269]	[1366,1551,1651,1376]	6	hSpCas9	negative selection	7627796
16853712	16853735	X	-	27260156	LNCAPCLONEFGC	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.5774080082427969	[926]	[1133,1031,1487,1408]	8	hSpCas9	negative selection	7627797
16852044	16852067	X	+	27260156	LNCAPCLONEFGC	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.46589676916487055	[1146]	[1567,1067,1778,1396]	7	hSpCas9	negative selection	7692051
16852054	16852077	X	-	27260156	LNCAPCLONEFGC	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.4222807467092602	[194]	[256,292,232,158]	6	hSpCas9	negative selection	7692052
16863057	16863080	X	+	27260156	LNCAPCLONEFGC	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.3418615059884237	[277]	[263,315,347,353]	5	hSpCas9	negative selection	7692053
16869502	16869525	X	+	27260156	PANC0327	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.17236103632448452	[1158]	[1522,866,1138,1178]	2	hSpCas9	negative selection	7749046
16869511	16869534	X	-	27260156	PANC0327	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.20338107142099293	[1269]	[1690,812,1236,1548]	3	hSpCas9	negative selection	7749047
16853712	16853735	X	-	27260156	PANC0327	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3645588621407182	[926]	[858,1078,1299,983]	5	hSpCas9	negative selection	7749048
16852044	16852067	X	+	27260156	PANC0327	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.18936934953496265	[1146]	[1187,1216,1184,1051]	3	hSpCas9	negative selection	7813302
16852054	16852077	X	-	27260156	PANC0327	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.6217501309965239	[194]	[123,74,102,153]	-7	hSpCas9	negative selection	7813303
16863057	16863080	X	+	27260156	PANC0327	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.5196247954737281	[277]	[135,180,225,141]	-6	hSpCas9	negative selection	7813304
16869502	16869525	X	+	27260156	NCIH2009	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.20635738158020045	[1158]	[2105,1522,2025]	3	hSpCas9	negative selection	7870297
16869511	16869534	X	-	27260156	NCIH2009	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.2802804856270169	[1269]	[2194,2203,2068]	4	hSpCas9	negative selection	7870298
16853712	16853735	X	-	27260156	NCIH2009	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.5593415359075019	[926]	[2587,1616,1656]	7	hSpCas9	negative selection	7870299
16852044	16852067	X	+	27260156	NCIH2009	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.37952035318963717	[1146]	[2503,1621,2215]	5	hSpCas9	negative selection	7934553
16852054	16852077	X	-	27260156	NCIH2009	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.40928871136476686	[194]	[482,294,331]	5	hSpCas9	negative selection	7934554
16863057	16863080	X	+	27260156	NCIH2009	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.29026661828563616	[277]	[694,397,375]	4	hSpCas9	negative selection	7934555
16869502	16869525	X	+	27260156	NCIH1373	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.04171048760213192	[1158]	[1340,1614,903,385]	0	hSpCas9	negative selection	7991548
16869511	16869534	X	-	27260156	NCIH1373	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.3872237945228336	[1269]	[2584,1215,1847,519]	4	hSpCas9	negative selection	7991549
16853712	16853735	X	-	27260156	NCIH1373	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.8643013489515475	[926]	[2003,1702,1618,603]	8	hSpCas9	negative selection	7991550
16852044	16852067	X	+	27260156	NCIH1373	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.41798525573210643	[1146]	[1927,1093,1838,557]	4	hSpCas9	negative selection	8055804
16852054	16852077	X	-	27260156	NCIH1373	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.48645214733214315	[194]	[151,344,261,116]	5	hSpCas9	negative selection	8055805
16863057	16863080	X	+	27260156	NCIH1373	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.27825443558105034	[277]	[365,390,214,143]	2	hSpCas9	negative selection	8055806
16869502	16869525	X	+	27260156	PATU8902	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.6462197503645437	[1158]	[2541,2255,2078,3430]	6	hSpCas9	negative selection	8112799
16869511	16869534	X	-	27260156	PATU8902	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.64215297608389	[1269]	[2941,3197,2235,2780]	6	hSpCas9	negative selection	8112800
16853712	16853735	X	-	27260156	PATU8902	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.9916981432040107	[926]	[2540,2546,1843,3631]	9	hSpCas9	negative selection	8112801
16852044	16852067	X	+	27260156	PATU8902	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.8076845084226356	[1146]	[2073,2878,2591,3799]	8	hSpCas9	negative selection	8177055
16852054	16852077	X	-	27260156	PATU8902	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.4506887771675555	[194]	[259,416,435,350]	4	hSpCas9	negative selection	8177056
16863057	16863080	X	+	27260156	PATU8902	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.4065054063431885	[277]	[556,455,482,565]	4	hSpCas9	negative selection	8177057
16869502	16869525	X	+	27260156	PANC1	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.3029847995437107	[1158]	[1286,1388,1349,945]	5	hSpCas9	negative selection	8234050
16869511	16869534	X	-	27260156	PANC1	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.23030725130174212	[1269]	[1419,1699,1311,824]	3	hSpCas9	negative selection	8234051
16853712	16853735	X	-	27260156	PANC1	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.43061714392755246	[926]	[923,1522,1255,726]	7	hSpCas9	negative selection	8234052
16852044	16852067	X	+	27260156	PANC1	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.30845162959154293	[1146]	[1012,1416,1480,1027]	5	hSpCas9	negative selection	8298306
16852054	16852077	X	-	27260156	PANC1	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.11882446933526758	[194]	[125,236,109,157]	-2	hSpCas9	negative selection	8298307
16863057	16863080	X	+	27260156	PANC1	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.30333183008002057	[277]	[248,392,227,319]	5	hSpCas9	negative selection	8298308
16869502	16869525	X	+	27260156	PANC0813	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.22690746298358477	[1158]	[1888,1525,1338,1639]	3	hSpCas9	negative selection	8355301
16869511	16869534	X	-	27260156	PANC0813	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.3772747341065861	[1269]	[2149,1985,1745,1886]	6	hSpCas9	negative selection	8355302
16853712	16853735	X	-	27260156	PANC0813	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3477413967900346	[926]	[1437,1459,1232,1411]	5	hSpCas9	negative selection	8355303
16852044	16852067	X	+	27260156	PANC0813	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.14628684031858752	[1146]	[1425,1430,1805,1304]	2	hSpCas9	negative selection	8419557
16852054	16852077	X	-	27260156	PANC0813	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.15794572956955655	[194]	[223,231,407,160]	2	hSpCas9	negative selection	8419558
16863057	16863080	X	+	27260156	PANC0813	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.1632269164086616	[277]	[388,254,208,319]	-3	hSpCas9	negative selection	8419559
16869502	16869525	X	+	27260156	RDES	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.320055458438935	[1158]	[1282,1766,1992,1643]	5	hSpCas9	negative selection	8476552
16869511	16869534	X	-	27260156	RDES	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.23440597665923746	[1269]	[1462,1463,1783,2276]	4	hSpCas9	negative selection	8476553
16853712	16853735	X	-	27260156	RDES	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.6338010868209235	[926]	[1433,1594,1705,1925]	8	hSpCas9	negative selection	8476554
16852044	16852067	X	+	27260156	RDES	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.4610385082570876	[1146]	[1539,1655,2027,2110]	7	hSpCas9	negative selection	8540808
16852054	16852077	X	-	27260156	RDES	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.3475397481728564	[194]	[217,243,301,406]	5	hSpCas9	negative selection	8540809
16863057	16863080	X	+	27260156	RDES	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.3104765201592057	[277]	[299,364,408,547]	5	hSpCas9	negative selection	8540810
16869502	16869525	X	+	27260156	PC3	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.19337423228288442	[1158]	[893,1379,2093,1258]	4	hSpCas9	negative selection	8597803
16869511	16869534	X	-	27260156	PC3	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.06680457276277063	[1269]	[853,865,2068,1436]	-1	hSpCas9	negative selection	8597804
16853712	16853735	X	-	27260156	PC3	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.2229920278674583	[926]	[620,1017,2046,1113]	5	hSpCas9	negative selection	8597805
16852044	16852067	X	+	27260156	PC3	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.1952354183239704	[1146]	[864,1166,2400,1297]	4	hSpCas9	negative selection	8662059
16852054	16852077	X	-	27260156	PC3	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.2532421078137739	[194]	[132,244,226,345]	5	hSpCas9	negative selection	8662060
16863057	16863080	X	+	27260156	PC3	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.015168379335652182	[277]	[159,268,319,395]	0	hSpCas9	negative selection	8662061
16869502	16869525	X	+	27260156	PATU8988T	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.35954621861582314	[1158]	[1860,1357,1194,1319]	6	hSpCas9	negative selection	8719054
16869511	16869534	X	-	27260156	PATU8988T	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.28771479830178404	[1269]	[1126,1421,2075,1338]	5	hSpCas9	negative selection	8719055
16853712	16853735	X	-	27260156	PATU8988T	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.20868561813611863	[926]	[1212,913,792,1227]	3	hSpCas9	negative selection	8719056
16852044	16852067	X	+	27260156	PATU8988T	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.15209223004827144	[1146]	[1232,1312,1300,1072]	2	hSpCas9	negative selection	8783310
16852054	16852077	X	-	27260156	PATU8988T	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.7077048479148915	[194]	[30,165,71,204]	-8	hSpCas9	negative selection	8783311
16863057	16863080	X	+	27260156	PATU8988T	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.31896175168148266	[277]	[178,359,152,180]	-5	hSpCas9	negative selection	8783312
16869502	16869525	X	+	27260156	T47D	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	-0.024215303739009597	[1158]	[1286,1297,1374,1352]	0	hSpCas9	negative selection	8840305
16869511	16869534	X	-	27260156	T47D	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.10063394641755807	[1269]	[1565,1494,1564,1731]	2	hSpCas9	negative selection	8840306
16853712	16853735	X	-	27260156	T47D	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3018031639326205	[926]	[1399,1237,1268,1429]	6	hSpCas9	negative selection	8840307
16852044	16852067	X	+	27260156	T47D	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.09576186781086249	[1146]	[1440,1462,1256,1553]	2	hSpCas9	negative selection	8904561
16852054	16852077	X	-	27260156	T47D	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.09051475952049914	[194]	[221,210,237,300]	2	hSpCas9	negative selection	8904562
16863057	16863080	X	+	27260156	T47D	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.37327727842114267	[277]	[278,220,265,235]	-7	hSpCas9	negative selection	8904563
16869502	16869525	X	+	27260156	SU8686	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.12296933493305051	[1158]	[1038,1083,1249,1749]	2	hSpCas9	negative selection	8961556
16869511	16869534	X	-	27260156	SU8686	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.47776221506055383	[1269]	[1721,1269,1874,2290]	7	hSpCas9	negative selection	8961557
16853712	16853735	X	-	27260156	SU8686	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.49100702750962555	[926]	[1143,1300,1307,1444]	7	hSpCas9	negative selection	8961558
16852044	16852067	X	+	27260156	SU8686	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.10485427132547676	[1146]	[1153,1095,1401,1266]	1	hSpCas9	negative selection	9025812
16852054	16852077	X	-	27260156	SU8686	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.3367456373707951	[194]	[176,220,223,385]	6	hSpCas9	negative selection	9025813
16863057	16863080	X	+	27260156	SU8686	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.09589479165776893	[277]	[262,288,281,355]	1	hSpCas9	negative selection	9025814
16869502	16869525	X	+	27260156	SKES1	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.19318115946643033	[1158]	[1430,1805,1162,988]	4	hSpCas9	negative selection	9082807
16869511	16869534	X	-	27260156	SKES1	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.11636701502060132	[1269]	[1695,1509,1358,1017]	2	hSpCas9	negative selection	9082808
16853712	16853735	X	-	27260156	SKES1	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3739589524552428	[926]	[1411,1121,989,1270]	7	hSpCas9	negative selection	9082809
16852044	16852067	X	+	27260156	SKES1	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.10695162385681867	[1146]	[1243,1155,1258,1246]	2	hSpCas9	negative selection	9147063
16852054	16852077	X	-	27260156	SKES1	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	-0.17752748468647495	[194]	[94,178,171,223]	-4	hSpCas9	negative selection	9147064
16863057	16863080	X	+	27260156	SKES1	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.1884906362732136	[277]	[319,227,398,303]	4	hSpCas9	negative selection	9147065
16869502	16869525	X	+	27260156	TOV112D	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.04660494920317926	[1158]	[1183,1428,927,1304]	0	hSpCas9	negative selection	9204058
16869511	16869534	X	-	27260156	TOV112D	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.20989806856179483	[1269]	[1569,1888,1266,1272]	4	hSpCas9	negative selection	9204059
16853712	16853735	X	-	27260156	TOV112D	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.4147957623967634	[926]	[1096,1541,1322,1054]	7	hSpCas9	negative selection	9204060
16852044	16852067	X	+	27260156	TOV112D	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.3147193711482148	[1146]	[1561,1733,1247,1259]	6	hSpCas9	negative selection	9268314
16852054	16852077	X	-	27260156	TOV112D	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.4774143188488058	[194]	[212,392,341,166]	8	hSpCas9	negative selection	9268315
16863057	16863080	X	+	27260156	TOV112D	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.06343444773740503	[277]	[224,243,307,278]	-1	hSpCas9	negative selection	9268316
16869502	16869525	X	+	27260156	TC71	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.018805469881828296	[1158]	[1393,1280,1089,1272]	0	hSpCas9	negative selection	9325309
16869511	16869534	X	-	27260156	TC71	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.025564205006308738	[1269]	[1341,1634,1218,1350]	0	hSpCas9	negative selection	9325310
16853712	16853735	X	-	27260156	TC71	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.3899296154354851	[926]	[1209,1348,1254,1403]	8	hSpCas9	negative selection	9325311
16852044	16852067	X	+	27260156	TC71	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.2249032053025184	[1146]	[1419,1490,1362,1478]	5	hSpCas9	negative selection	9389565
16852054	16852077	X	-	27260156	TC71	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.30221831140394007	[194]	[298,227,209,296]	7	hSpCas9	negative selection	9389566
16863057	16863080	X	+	27260156	TC71	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	0.10591658870980558	[277]	[326,269,325,361]	2	hSpCas9	negative selection	9389567
16869502	16869525	X	+	27260156	TC32	viability	AGATGACGACCTGTACGTACAGG	RBBP7	ENSG00000102054	0.1466933634481271	[1158]	[1226,874,1357,1452]	2	hSpCas9	negative selection	9446560
16869511	16869534	X	-	27260156	TC32	viability	CGCGCAGCCCCTGTACGTACAGG	RBBP7	ENSG00000102054	0.10290263383683063	[1269]	[1205,938,1596,1515]	2	hSpCas9	negative selection	9446561
16853712	16853735	X	-	27260156	TC32	viability	CTGCTGCACGAGTCATTGTTTGG	RBBP7	ENSG00000102054	0.2966071480521265	[926]	[974,627,1523,1368]	5	hSpCas9	negative selection	9446562
16852044	16852067	X	+	27260156	TC32	viability	ACCTTAAATCCCACACATTCAGG	RBBP7	ENSG00000102054	0.24347847373486142	[1146]	[1043,987,1576,1630]	4	hSpCas9	negative selection	9510816
16852054	16852077	X	-	27260156	TC32	viability	CTGACCGCCGCCTGAATGTGTGG	RBBP7	ENSG00000102054	0.571628926018579	[194]	[222,298,221,316]	8	hSpCas9	negative selection	9510817
16863057	16863080	X	+	27260156	TC32	viability	TCCCCAGCACTAGCCAATGAAGG	RBBP7	ENSG00000102054	-0.5889543556217256	[277]	[200,87,153,272]	-8	hSpCas9	negative selection	9510818
16852746	16852769	X	+	27869803	HPAFII	viability after 27 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-2.2370167302565065	[171]	[40,0,NaN]	-8	hSpCas9	negative selection	9608334
16853713	16853736	X	+	27869803	HPAFII	viability after 27 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.6507248697024224	[81]	[214,68,NaN]	9	hSpCas9	negative selection	9608335
16858754	16858777	X	+	27869803	HPAFII	viability after 27 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-1.3702993438442865	[383]	[76,78,NaN]	-7	hSpCas9	negative selection	9608336
16862955	16862978	X	+	27869803	HPAFII	viability after 27 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.1553151949096692	[1067]	[274,232,NaN]	-7	hSpCas9	negative selection	9608337
16869090	16869113	X	+	27869803	HPAFII	viability after 27 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-1.3888932104195508	[167]	[48,20,NaN]	-7	hSpCas9	negative selection	9608338
16869504	16869527	X	+	27869803	HPAFII	viability after 27 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-1.4407032762033984	[137]	[23,28,NaN]	-7	hSpCas9	negative selection	9608339
16852746	16852769	X	+	27869803	HPAFII	viability after 15 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-1.108843243117057	[171]	[192,18,NaN]	-8	hSpCas9	negative selection	9690783
16853713	16853736	X	+	27869803	HPAFII	viability after 15 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.4080103356103648	[81]	[223,239,NaN]	9	hSpCas9	negative selection	9690784
16858754	16858777	X	+	27869803	HPAFII	viability after 15 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.7741132499484842	[383]	[310,197,NaN]	-7	hSpCas9	negative selection	9690785
16862955	16862978	X	+	27869803	HPAFII	viability after 15 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.08867825241791838	[1067]	[1510,1039,NaN]	1	hSpCas9	negative selection	9690786
16869090	16869113	X	+	27869803	HPAFII	viability after 15 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-0.175112554540913	[167]	[162,157,NaN]	-2	hSpCas9	negative selection	9690787
16869504	16869527	X	+	27869803	HPAFII	viability after 15 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.11841639076702482	[137]	[53,187,NaN]	-1	hSpCas9	negative selection	9690788
16852746	16852769	X	+	27869803	ASPC1	viability after 36 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-0.7438632842452981	[468]	[106,87,97]	-6	hSpCas9	negative selection	9773232
16853713	16853736	X	+	27869803	ASPC1	viability after 36 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.8352481818326702	[392]	[466,0,887]	9	hSpCas9	negative selection	9773233
16858754	16858777	X	+	27869803	ASPC1	viability after 36 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-0.030614936870117515	[911]	[299,324,305]	0	hSpCas9	negative selection	9773234
16862955	16862978	X	+	27869803	ASPC1	viability after 36 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	0.0884146012997915	[2548]	[873,1136,834]	0	hSpCas9	negative selection	9773235
16869090	16869113	X	+	27869803	ASPC1	viability after 36 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-0.014058986292705411	[409]	[99,91,208]	0	hSpCas9	negative selection	9773236
16869504	16869527	X	+	27869803	ASPC1	viability after 36 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	1.1433975088125963	[444]	[377,278,365]	9	hSpCas9	negative selection	9773237
16852746	16852769	X	+	27869803	PATU8988S	viability after 35 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-2.284756698878317	[435]	[51,19,NaN]	-9	hSpCas9	negative selection	9855681
16853713	16853736	X	+	27869803	PATU8988S	viability after 35 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	-0.19769851947240524	[416]	[119,172,NaN]	-2	hSpCas9	negative selection	9855682
16858754	16858777	X	+	27869803	PATU8988S	viability after 35 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-2.1267630157970445	[861]	[75,82,NaN]	-9	hSpCas9	negative selection	9855683
16862955	16862978	X	+	27869803	PATU8988S	viability after 35 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.6837347522471429	[2217]	[610,500,NaN]	-6	hSpCas9	negative selection	9855684
16869090	16869113	X	+	27869803	PATU8988S	viability after 35 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-1.746182304581052	[361]	[25,60,NaN]	-8	hSpCas9	negative selection	9855685
16869504	16869527	X	+	27869803	PATU8988S	viability after 35 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	0.28983603801168767	[393]	[189,197,NaN]	3	hSpCas9	negative selection	9855686
16852746	16852769	X	+	27869803	PATU8988S	viability after 31 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-3.3473431648917873	[435]	[24,6,NaN]	-9	hSpCas9	negative selection	9938130
16853713	16853736	X	+	27869803	PATU8988S	viability after 31 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	0.34598658635430524	[416]	[114,333,NaN]	4	hSpCas9	negative selection	9938131
16858754	16858777	X	+	27869803	PATU8988S	viability after 31 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-1.7252349361093287	[861]	[88,122,NaN]	-8	hSpCas9	negative selection	9938132
16862955	16862978	X	+	27869803	PATU8988S	viability after 31 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-0.5211049948557982	[2217]	[482,785,NaN]	-5	hSpCas9	negative selection	9938133
16869090	16869113	X	+	27869803	PATU8988S	viability after 31 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-1.442375294685923	[361]	[20,93,NaN]	-8	hSpCas9	negative selection	9938134
16869504	16869527	X	+	27869803	PATU8988S	viability after 31 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.08447440131733902	[393]	[196,85,NaN]	-1	hSpCas9	negative selection	9938135
16852746	16852769	X	+	27869803	HPAFII	viability after 35 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-3.1216779842890494	[171]	[17,0,NaN]	-8	hSpCas9	negative selection	10020579
16853713	16853736	X	+	27869803	HPAFII	viability after 35 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.3712699187936186	[81]	[184,19,NaN]	8	hSpCas9	negative selection	10020580
16858754	16858777	X	+	27869803	HPAFII	viability after 35 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-1.6613333433129358	[383]	[36,88,NaN]	-7	hSpCas9	negative selection	10020581
16862955	16862978	X	+	27869803	HPAFII	viability after 35 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.2726787494245704	[1067]	[132,325,NaN]	-6	hSpCas9	negative selection	10020582
16869090	16869113	X	+	27869803	HPAFII	viability after 35 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-1.605727944779634	[167]	[34,19,NaN]	-7	hSpCas9	negative selection	10020583
16869504	16869527	X	+	27869803	HPAFII	viability after 35 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-1.1420230741640331	[137]	[49,10,NaN]	-6	hSpCas9	negative selection	10020584
16852746	16852769	X	+	27869803	HPAFII	viability after 31 days	AACCTTATCCGCAGAGCCGGTGG	RBBP7	ENSG00000102054	-1.9802882992365551	[171]	[45,0,NaN]	-8	hSpCas9	negative selection	10103028
16853713	16853736	X	+	27869803	HPAFII	viability after 31 days	CAAACAATGACTCGTGCAGCAGG	RBBP7	ENSG00000102054	1.5718942645667209	[81]	[221,43,NaN]	9	hSpCas9	negative selection	10103029
16858754	16858777	X	+	27869803	HPAFII	viability after 31 days	TCTGCGGCATGTAACGAGCACGG	RBBP7	ENSG00000102054	-2.6365104828703547	[383]	[26,42,NaN]	-8	hSpCas9	negative selection	10103030
16862955	16862978	X	+	27869803	HPAFII	viability after 31 days	CACCCTTGTCACTGTCACAATGG	RBBP7	ENSG00000102054	-1.25074015223663	[1067]	[170,339,NaN]	-6	hSpCas9	negative selection	10103031
16869090	16869113	X	+	27869803	HPAFII	viability after 31 days	AAGCCACTGAACGGTAAGACTGG	RBBP7	ENSG00000102054	-2.7289517343279663	[167]	[7,20,NaN]	-8	hSpCas9	negative selection	10103032
16869504	16869527	X	+	27869803	HPAFII	viability after 31 days	ATGACGACCTGTACGTACAGGGG	RBBP7	ENSG00000102054	-0.9692869356809473	[137]	[51,25,NaN]	-6	hSpCas9	negative selection	10103033
16852833	16852856	X	+	28162770	P31FUJ	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.5130143073340934	[129]	[217]	6	hSpCas9	negative selection	10222813
16857655	16857678	X	-	28162770	P31FUJ	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.6234135940646293	[563]	[1020]	7	hSpCas9	negative selection	10222814
16853802	16853825	X	-	28162770	P31FUJ	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.120834750200322	[26]	[68]	9	hSpCas9	negative selection	10222815
16845859	16845882	X	+	28162770	P31FUJ	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.2772445895288669	[414]	[590]	3	hSpCas9	negative selection	10222816
16869200	16869223	X	-	28162770	P31FUJ	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.5151658838092993	[417]	[701]	6	hSpCas9	negative selection	10222817
16852079	16852102	X	-	28162770	P31FUJ	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.08008075086997679	[127]	[158]	0	hSpCas9	negative selection	10222818
16852050	16852073	X	+	28162770	P31FUJ	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	1.2956774761210301	[190]	[550]	9	hSpCas9	negative selection	10222819
16845876	16845899	X	-	28162770	P31FUJ	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.6902358137707371	[153]	[291]	7	hSpCas9	negative selection	10222820
16869107	16869130	X	+	28162770	P31FUJ	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.6098973330083686	[575]	[1032]	7	hSpCas9	negative selection	10222821
16863024	16863047	X	-	28162770	P31FUJ	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	1.3899152183021957	[87]	[270]	9	hSpCas9	negative selection	10222822
16852833	16852856	X	+	28162770	TF1	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10392179
16857655	16857678	X	-	28162770	TF1	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	NaN	[NaN]	[915]	1	hSpCas9	negative selection	10392180
16853802	16853825	X	-	28162770	TF1	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10392181
16845859	16845882	X	+	28162770	TF1	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	NaN	[NaN]	[381]	1	hSpCas9	negative selection	10392182
16869200	16869223	X	-	28162770	TF1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	NaN	[NaN]	[517]	1	hSpCas9	negative selection	10392183
16852079	16852102	X	-	28162770	TF1	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10392184
16852050	16852073	X	+	28162770	TF1	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10392185
16845876	16845899	X	-	28162770	TF1	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10392186
16869107	16869130	X	+	28162770	TF1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	NaN	[NaN]	[535]	1	hSpCas9	negative selection	10392187
16863024	16863047	X	-	28162770	TF1	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10392188
16852833	16852856	X	+	28162770	SKM1	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	-0.7548875021634686	[41]	[43]	-5	hSpCas9	negative selection	10561545
16857655	16857678	X	-	28162770	SKM1	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.3625700793847081	[135]	[186]	-3	hSpCas9	negative selection	10561546
16853802	16853825	X	-	28162770	SKM1	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.4190064014817896	[10]	[51]	9	hSpCas9	negative selection	10561547
16845859	16845882	X	+	28162770	SKM1	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.038068040833519445	[118]	[215]	0	hSpCas9	negative selection	10561548
16869200	16869223	X	-	28162770	SKM1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.27016814590586136	[143]	[306]	2	hSpCas9	negative selection	10561549
16852079	16852102	X	-	28162770	SKM1	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.930070788534409	[37]	[127]	8	hSpCas9	negative selection	10561550
16852050	16852073	X	+	28162770	SKM1	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.32557587190250664	[55]	[78]	-3	hSpCas9	negative selection	10561551
16845876	16845899	X	-	28162770	SKM1	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.38745166760694444	[31]	[73]	4	hSpCas9	negative selection	10561552
16869107	16869130	X	+	28162770	SKM1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.2304657218721302	[134]	[279]	2	hSpCas9	negative selection	10561553
16863024	16863047	X	-	28162770	SKM1	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10561554
16852833	16852856	X	+	28162770	SKM1	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	-0.7548875021634686	[41]	[43]	-5	hSpCas9	negative selection	10730911
16857655	16857678	X	-	28162770	SKM1	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.3625700793847081	[135]	[186]	-3	hSpCas9	negative selection	10730912
16853802	16853825	X	-	28162770	SKM1	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.4190064014817896	[10]	[51]	9	hSpCas9	negative selection	10730913
16845859	16845882	X	+	28162770	SKM1	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.038068040833519445	[118]	[215]	0	hSpCas9	negative selection	10730914
16869200	16869223	X	-	28162770	SKM1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.27016814590586136	[143]	[306]	2	hSpCas9	negative selection	10730915
16852079	16852102	X	-	28162770	SKM1	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.930070788534409	[37]	[127]	8	hSpCas9	negative selection	10730916
16852050	16852073	X	+	28162770	SKM1	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.32557587190250664	[55]	[78]	-3	hSpCas9	negative selection	10730917
16845876	16845899	X	-	28162770	SKM1	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.38745166760694444	[31]	[73]	4	hSpCas9	negative selection	10730918
16869107	16869130	X	+	28162770	SKM1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.2304657218721302	[134]	[279]	2	hSpCas9	negative selection	10730919
16863024	16863047	X	-	28162770	SKM1	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.4999263968653569	[15]	[39]	5	hSpCas9	negative selection	10730920
16852833	16852856	X	+	28162770	PL21	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.8636141433889998	[148]	[117]	7	hSpCas9	negative selection	10900277
16857655	16857678	X	-	28162770	PL21	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.17212523831972337	[415]	[203]	1	hSpCas9	negative selection	10900278
16853802	16853825	X	-	28162770	PL21	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	0.15574549513086655	[32]	[15]	1	hSpCas9	negative selection	10900279
16845859	16845882	X	+	28162770	PL21	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.380711860131141	[419]	[237]	3	hSpCas9	negative selection	10900280
16869200	16869223	X	-	28162770	PL21	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.3283495967690604	[537]	[293]	3	hSpCas9	negative selection	10900281
16852079	16852102	X	-	28162770	PL21	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.11964969662895214	[128]	[60]	1	hSpCas9	negative selection	10900282
16852050	16852073	X	+	28162770	PL21	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.5467901387879139	[161]	[102]	5	hSpCas9	negative selection	10900283
16845876	16845899	X	-	28162770	PL21	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	1.2001396144893204	[118]	[118]	8	hSpCas9	negative selection	10900284
16869107	16869130	X	+	28162770	PL21	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	1.0704257922733809	[313]	[286]	8	hSpCas9	negative selection	10900285
16863024	16863047	X	-	28162770	PL21	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.37101708670680544	[103]	[34]	-3	hSpCas9	negative selection	10900286
16852833	16852856	X	+	28162770	P31FUJ	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.5130143073340934	[129]	[217]	6	hSpCas9	negative selection	11069643
16857655	16857678	X	-	28162770	P31FUJ	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.6234135940646293	[563]	[1020]	7	hSpCas9	negative selection	11069644
16853802	16853825	X	-	28162770	P31FUJ	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.120834750200322	[26]	[68]	9	hSpCas9	negative selection	11069645
16845859	16845882	X	+	28162770	P31FUJ	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.2772445895288669	[414]	[590]	3	hSpCas9	negative selection	11069646
16869200	16869223	X	-	28162770	P31FUJ	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.5151658838092993	[417]	[701]	6	hSpCas9	negative selection	11069647
16852079	16852102	X	-	28162770	P31FUJ	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.08008075086997679	[127]	[158]	0	hSpCas9	negative selection	11069648
16852050	16852073	X	+	28162770	P31FUJ	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	1.2956774761210301	[190]	[550]	9	hSpCas9	negative selection	11069649
16845876	16845899	X	-	28162770	P31FUJ	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.6902358137707371	[153]	[291]	7	hSpCas9	negative selection	11069650
16869107	16869130	X	+	28162770	P31FUJ	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.6098973330083686	[575]	[1032]	7	hSpCas9	negative selection	11069651
16863024	16863047	X	-	28162770	P31FUJ	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	1.3899152183021957	[87]	[270]	9	hSpCas9	negative selection	11069652
16852833	16852856	X	+	28162770	OCIAML5	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.7461927524706167	[71]	[217]	6	hSpCas9	negative selection	11239009
16857655	16857678	X	-	28162770	OCIAML5	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.04323605046930967	[349]	[650]	0	hSpCas9	negative selection	11239010
16853802	16853825	X	-	28162770	OCIAML5	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-0.40226365342447656	[40]	[55]	-3	hSpCas9	negative selection	11239011
16845859	16845882	X	+	28162770	OCIAML5	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.7890960686276245	[192]	[601]	7	hSpCas9	negative selection	11239012
16869200	16869223	X	-	28162770	OCIAML5	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.7277890394240705	[282]	[845]	6	hSpCas9	negative selection	11239013
16852079	16852102	X	-	28162770	OCIAML5	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	1.081506067397027	[49]	[190]	8	hSpCas9	negative selection	11239014
16852050	16852073	X	+	28162770	OCIAML5	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.7491061570384182	[117]	[357]	6	hSpCas9	negative selection	11239015
16845876	16845899	X	-	28162770	OCIAML5	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	1.5836303989809397	[38]	[210]	9	hSpCas9	negative selection	11239016
16869107	16869130	X	+	28162770	OCIAML5	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.6812452993416256	[217]	[630]	6	hSpCas9	negative selection	11239017
16863024	16863047	X	-	28162770	OCIAML5	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	1.0713121475330907	[28]	[109]	8	hSpCas9	negative selection	11239018
16852833	16852856	X	+	28162770	EOL1	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	1.9450951489746202	[243]	[494]	9	hSpCas9	negative selection	11408375
16857655	16857678	X	-	28162770	EOL1	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.30592310348784346	[541]	[352]	2	hSpCas9	negative selection	11408376
16853802	16853825	X	-	28162770	EOL1	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-1.0754522284294654	[67]	[16]	-6	hSpCas9	negative selection	11408377
16845859	16845882	X	+	28162770	EOL1	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.003362154747363011	[747]	[394]	0	hSpCas9	negative selection	11408378
16869200	16869223	X	-	28162770	EOL1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.10960915359488	[905]	[514]	1	hSpCas9	negative selection	11408379
16852079	16852102	X	-	28162770	EOL1	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.035579083959278224	[199]	[107]	0	hSpCas9	negative selection	11408380
16852050	16852073	X	+	28162770	EOL1	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.20652374105778876	[226]	[137]	1	hSpCas9	negative selection	11408381
16845876	16845899	X	-	28162770	EOL1	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.5179225121078908	[113]	[85]	5	hSpCas9	negative selection	11408382
16869107	16869130	X	+	28162770	EOL1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.28990566832686215	[516]	[332]	2	hSpCas9	negative selection	11408383
16863024	16863047	X	-	28162770	EOL1	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.43619957220735595	[112]	[43]	-3	hSpCas9	negative selection	11408384
16852833	16852856	X	+	28162770	MOLM13	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	1.24758027470862	[172]	[296]	8	hSpCas9	negative selection	11577741
16857655	16857678	X	-	28162770	MOLM13	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.009588692510172137	[542]	[389]	0	hSpCas9	negative selection	11577742
16853802	16853825	X	-	28162770	MOLM13	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.766547697109094	[49]	[122]	9	hSpCas9	negative selection	11577743
16845859	16845882	X	+	28162770	MOLM13	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.3036261049720055	[603]	[538]	2	hSpCas9	negative selection	11577744
16869200	16869223	X	-	28162770	MOLM13	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.5323134870453112	[853]	[892]	4	hSpCas9	negative selection	11577745
16852079	16852102	X	-	28162770	MOLM13	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	-0.15794540059210538	[178]	[115]	-1	hSpCas9	negative selection	11577746
16852050	16852073	X	+	28162770	MOLM13	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	-0.36465387260385834	[259]	[145]	-2	hSpCas9	negative selection	11577747
16845876	16845899	X	-	28162770	MOLM13	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	-1.1703713453366265	[192]	[61]	-6	hSpCas9	negative selection	11577748
16869107	16869130	X	+	28162770	MOLM13	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.24104762733416607	[432]	[369]	1	hSpCas9	negative selection	11577749
16863024	16863047	X	-	28162770	MOLM13	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-1.7615924645781882	[135]	[28]	-7	hSpCas9	negative selection	11577750
16852833	16852856	X	+	28162770	HEL	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.1502225800437958	[203]	[144]	1	hSpCas9	negative selection	11747107
16857655	16857678	X	-	28162770	HEL	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.24116410307677172	[536]	[290]	-2	hSpCas9	negative selection	11747108
16853802	16853825	X	-	28162770	HEL	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	1.6862404706369434	[48]	[100]	9	hSpCas9	negative selection	11747109
16845859	16845882	X	+	28162770	HEL	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	-0.24396160388507737	[611]	[330]	-2	hSpCas9	negative selection	11747110
16869200	16869223	X	-	28162770	HEL	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	1.094411332907853	[660]	[903]	8	hSpCas9	negative selection	11747111
16852079	16852102	X	-	28162770	HEL	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	-1.2582511621684773	[182]	[48]	-6	hSpCas9	negative selection	11747112
16852050	16852073	X	+	28162770	HEL	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.5885467316367604	[216]	[208]	5	hSpCas9	negative selection	11747113
16845876	16845899	X	-	28162770	HEL	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.5366104811390139	[140]	[130]	4	hSpCas9	negative selection	11747114
16869107	16869130	X	+	28162770	HEL	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.7384628916012522	[378]	[404]	6	hSpCas9	negative selection	11747115
16863024	16863047	X	-	28162770	HEL	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-0.023837434274451397	[99]	[62]	0	hSpCas9	negative selection	11747116
16852833	16852856	X	+	28162770	MV411	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.5170446105400555	[145]	[175]	4	hSpCas9	negative selection	11916473
16857655	16857678	X	-	28162770	MV411	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.18478194293300798	[399]	[382]	1	hSpCas9	negative selection	11916474
16853802	16853825	X	-	28162770	MV411	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-1.5785330494421759	[38]	[10]	-7	hSpCas9	negative selection	11916475
16845859	16845882	X	+	28162770	MV411	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.7969013702825454	[383]	[561]	7	hSpCas9	negative selection	11916476
16869200	16869223	X	-	28162770	MV411	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	1.146463772942895	[465]	[868]	8	hSpCas9	negative selection	11916477
16852079	16852102	X	-	28162770	MV411	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.04098667331534894	[134]	[116]	0	hSpCas9	negative selection	11916478
16852050	16852073	X	+	28162770	MV411	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	1.2474375507827753	[156]	[313]	9	hSpCas9	negative selection	11916479
16845876	16845899	X	-	28162770	MV411	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.04812874255936861	[92]	[80]	0	hSpCas9	negative selection	11916480
16869107	16869130	X	+	28162770	MV411	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.25642633401003	[319]	[321]	2	hSpCas9	negative selection	11916481
16863024	16863047	X	-	28162770	MV411	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.5834867539147905	[60]	[76]	5	hSpCas9	negative selection	11916482
16852833	16852856	X	+	28162770	MONOMAC1	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	-0.5084979428958474	[102]	[82]	-4	hSpCas9	negative selection	12085839
16857655	16857678	X	-	28162770	MONOMAC1	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	-0.08426891689760396	[245]	[265]	0	hSpCas9	negative selection	12085840
16853802	16853825	X	-	28162770	MONOMAC1	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	-0.027111845617241226	[23]	[26]	0	hSpCas9	negative selection	12085841
16845859	16845882	X	+	28162770	MONOMAC1	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.03357608108186261	[299]	[351]	0	hSpCas9	negative selection	12085842
16869200	16869223	X	-	28162770	MONOMAC1	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.4343185591460539	[356]	[552]	4	hSpCas9	negative selection	12085843
16852079	16852102	X	-	28162770	MONOMAC1	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	-0.1970368470595535	[79]	[79]	-2	hSpCas9	negative selection	12085844
16852050	16852073	X	+	28162770	MONOMAC1	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.1491387940744859	[117]	[149]	1	hSpCas9	negative selection	12085845
16845876	16845899	X	-	28162770	MONOMAC1	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.9702578983380867	[60]	[136]	8	hSpCas9	negative selection	12085846
16869107	16869130	X	+	28162770	MONOMAC1	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	-0.3398374474585775	[190]	[172]	-3	hSpCas9	negative selection	12085847
16863024	16863047	X	-	28162770	MONOMAC1	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	-1.1254835860345198	[58]	[30]	-7	hSpCas9	negative selection	12085848
16852833	16852856	X	+	28162770	OCIAML2	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.9556349294599367	[23]	[257]	8	hSpCas9	negative selection	12255205
16857655	16857678	X	-	28162770	OCIAML2	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.30821240907303005	[72]	[500]	3	hSpCas9	negative selection	12255206
16853802	16853825	X	-	28162770	OCIAML2	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	0.3367250968154427	[4]	[34]	3	hSpCas9	negative selection	12255207
16845859	16845882	X	+	28162770	OCIAML2	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.22124787939550683	[90]	[587]	2	hSpCas9	negative selection	12255208
16869200	16869223	X	-	28162770	OCIAML2	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.00802377333265425	[121]	[679]	0	hSpCas9	negative selection	12255209
16852079	16852102	X	-	28162770	OCIAML2	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.33672509681544277	[26]	[188]	3	hSpCas9	negative selection	12255210
16852050	16852073	X	+	28162770	OCIAML2	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.13423223291669995	[35]	[218]	1	hSpCas9	negative selection	12255211
16845876	16845899	X	-	28162770	OCIAML2	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	0.22326704703215894	[16]	[109]	2	hSpCas9	negative selection	12255212
16869107	16869130	X	+	28162770	OCIAML2	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.5332020363488658	[46]	[376]	5	hSpCas9	negative selection	12255213
16863024	16863047	X	-	28162770	OCIAML2	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	0.37736708131278895	[9]	[71]	3	hSpCas9	negative selection	12255214
16852833	16852856	X	+	28162770	OCIAML3	viability	CAAGTGACTCGGCTTGGAGGTGG	RBBP7	ENSG00000102054	0.32655789218143183	[41]	[158]	3	hSpCas9	negative selection	12424571
16857655	16857678	X	-	28162770	OCIAML3	viability	TTAAGAGGTCACCAGAAGGAAGG	RBBP7	ENSG00000102054	0.10860644905126571	[152]	[497]	1	hSpCas9	negative selection	12424572
16853802	16853825	X	-	28162770	OCIAML3	viability	ATAAACGCAGGACCAAAAGAAGG	RBBP7	ENSG00000102054	0.9420452599160463	[4]	[28]	7	hSpCas9	negative selection	12424573
16845859	16845882	X	+	28162770	OCIAML3	viability	GACACTGAGCAAATGACCCAAGG	RBBP7	ENSG00000102054	0.41710431479606147	[96]	[390]	4	hSpCas9	negative selection	12424574
16869200	16869223	X	-	28162770	OCIAML3	viability	AGTGTTTGAAGATACTGTGGAGG	RBBP7	ENSG00000102054	0.5083540773055146	[135]	[583]	5	hSpCas9	negative selection	12424575
16852079	16852102	X	-	28162770	OCIAML3	viability	GAAACTATTCTGGCTTCAAGTGG	RBBP7	ENSG00000102054	0.7574647301772146	[28]	[147]	6	hSpCas9	negative selection	12424576
16852050	16852073	X	+	28162770	OCIAML3	viability	AATCCCACACATTCAGGCGGCGG	RBBP7	ENSG00000102054	0.4059923596758369	[29]	[119]	4	hSpCas9	negative selection	12424577
16845876	16845899	X	-	28162770	OCIAML3	viability	GCTGGAACCCCAATGAGCCTTGG	RBBP7	ENSG00000102054	-1.0214288640588394	[38]	[57]	-6	hSpCas9	negative selection	12424578
16869107	16869130	X	+	28162770	OCIAML3	viability	GACTGGGCCACTGAAGAGCATGG	RBBP7	ENSG00000102054	0.3204961393942305	[125]	[474]	3	hSpCas9	negative selection	12424579
16863024	16863047	X	-	28162770	OCIAML3	viability	TGATGAGCAGAATCATCTGGTGG	RBBP7	ENSG00000102054	2.39903959903407	[12]	[206]	9	hSpCas9	negative selection	12424580