Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 65055
• Symbol: REEP1
• Description: receptor accessory protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/REEP1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
86232738	86232761	2	-	26472758	Jiyoye	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.18197779684954063	[428]	[366]	1	hSpCas9	negative selection	135383
86251989	86252012	2	-	26472758	Jiyoye	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.9647933958810846	[87]	[33]	-6	hSpCas9	negative selection	135384
86232728	86232751	2	+	26472758	Jiyoye	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.7534718063484285	[464]	[207]	-5	hSpCas9	negative selection	135385
86232773	86232796	2	-	26472758	Jiyoye	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	-0.23875513650670976	[434]	[277]	-2	hSpCas9	negative selection	135386
86232635	86232658	2	+	26472758	Jiyoye	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.7802187921200902	[60]	[78]	5	hSpCas9	negative selection	135387
86232672	86232695	2	-	26472758	Jiyoye	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.6358933403860124	[67]	[32]	-4	hSpCas9	negative selection	135388
86232665	86232688	2	+	26472758	Jiyoye	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	135389
86263979	86264002	2	+	26472758	Jiyoye	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.2759308482276208	[91]	[83]	2	hSpCas9	negative selection	135390
86232757	86232780	2	-	26472758	Jiyoye	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	2.4071753815058727	[0]	[3]	9	hSpCas9	negative selection	135391
86232645	86232668	2	+	26472758	Jiyoye	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	1.4071753815058736	[67]	[135]	8	hSpCas9	negative selection	135392
86232738	86232761	2	-	26472758	KBM7	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.017615418012262074	[1883,1323]	[837,677]	0	hSpCas9	negative selection	326501
86251989	86252012	2	-	26472758	KBM7	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.18048865577165982	[512,303]	[202,221]	1	hSpCas9	negative selection	326502
86232728	86232751	2	+	26472758	KBM7	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-1.1670680030243605	[1315,1276]	[321,227]	-7	hSpCas9	negative selection	326503
86232773	86232796	2	-	26472758	KBM7	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.4637528582228132	[940,986]	[550,699]	5	hSpCas9	negative selection	326504
86232635	86232658	2	+	26472758	KBM7	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	1.0896325503006283	[190,116]	[130,168]	9	hSpCas9	negative selection	326505
86232672	86232695	2	-	26472758	KBM7	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.7069417461275849	[215,196]	[195,124]	7	hSpCas9	negative selection	326506
86232665	86232688	2	+	26472758	KBM7	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.17076943353270835	[5,3]	[0,2]	-2	hSpCas9	negative selection	326507
86263979	86264002	2	+	26472758	KBM7	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.13946815225272025	[649,769]	[406,341]	1	hSpCas9	negative selection	326508
86232757	86232780	2	-	26472758	KBM7	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-0.8722412737333434	[12,14]	[0,5]	-6	hSpCas9	negative selection	326509
86232645	86232668	2	+	26472758	KBM7	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.5047797084662154	[481,526]	[419,267]	5	hSpCas9	negative selection	326510
86232738	86232761	2	-	26472758	Raji	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.21628182556921338	[726]	[195]	2	hSpCas9	negative selection	517619
86251989	86252012	2	-	26472758	Raji	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.7062033403955192	[231]	[32]	-5	hSpCas9	negative selection	517620
86232728	86232751	2	+	26472758	Raji	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.6500461613523223	[851]	[125]	-5	hSpCas9	negative selection	517621
86232773	86232796	2	-	26472758	Raji	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.7337404039420818	[354]	[136]	7	hSpCas9	negative selection	517622
86232635	86232658	2	+	26472758	Raji	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	1.978100518428633	[34]	[31]	9	hSpCas9	negative selection	517623
86232672	86232695	2	-	26472758	Raji	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.9315336999741817	[60]	[26]	8	hSpCas9	negative selection	517624
86232665	86232688	2	+	26472758	Raji	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	5.5668151540108965	[0]	[10]	9	hSpCas9	negative selection	517625
86263979	86264002	2	+	26472758	Raji	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.2708822676564789	[249]	[69]	2	hSpCas9	negative selection	517626
86232757	86232780	2	-	26472758	Raji	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-2.0625414660687134	[17]	[0]	-8	hSpCas9	negative selection	517627
86232645	86232668	2	+	26472758	Raji	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	-0.054254854883752146	[433]	[96]	0	hSpCas9	negative selection	517628
86232738	86232761	2	-	26472758	K562	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.6322910171565137	[1098]	[1437]	5	hSpCas9	negative selection	708737
86251989	86252012	2	-	26472758	K562	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	1.0612771224124926	[280]	[494]	8	hSpCas9	negative selection	708738
86232728	86232751	2	+	26472758	K562	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-1.7845923589926214	[1305]	[319]	-7	hSpCas9	negative selection	708739
86232773	86232796	2	-	26472758	K562	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.5586524307638084	[751]	[934]	4	hSpCas9	negative selection	708740
86232635	86232658	2	+	26472758	K562	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	-0.052563010090684426	[128]	[104]	0	hSpCas9	negative selection	708741
86232672	86232695	2	-	26472758	K562	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.9551457642157394	[208]	[90]	-5	hSpCas9	negative selection	708742
86232665	86232688	2	+	26472758	K562	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	708743
86263979	86264002	2	+	26472758	K562	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.6969309323639535	[436]	[597]	6	hSpCas9	negative selection	708744
86232757	86232780	2	-	26472758	K562	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	4.999306229829916	[0]	[26]	9	hSpCas9	negative selection	708745
86232645	86232668	2	+	26472758	K562	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.062215396445697735	[530]	[467]	0	hSpCas9	negative selection	708746
86217039	86217062	2	+	26627737	DLD1	viability	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	-0.04563550236051217	[957]	[285,383,215]	0	hSpCas9	negative selection	812988
86232665	86232688	2	+	26627737	DLD1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.21991425198196796	[396]	[132,151,45]	-2	hSpCas9	negative selection	812989
86251977	86252000	2	-	26627737	DLD1	viability	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.6503346249548442	[1228]	[262,286,193]	-6	hSpCas9	negative selection	812990
86254724	86254747	2	+	26627737	DLD1	viability	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.4222603236540885	[196]	[41,43,50]	-4	hSpCas9	negative selection	812991
86263951	86263974	2	+	26627737	DLD1	viability	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.5285877472260214	[736]	[322,455,237]	5	hSpCas9	negative selection	812992
86338040	86338063	2	-	26627737	DLD1	viability	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.08885282363245961	[570]	[156,258,160]	0	hSpCas9	negative selection	812993
86217039	86217062	2	+	26627737	GBM cells	viability after 5 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.4402871070591592	[335]	[272,215]	6	hSpCas9	negative selection	895303
86232665	86232688	2	+	26627737	GBM cells	viability after 5 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.8989138748856855	[82]	[95,69]	9	hSpCas9	negative selection	895304
86251977	86252000	2	-	26627737	GBM cells	viability after 5 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.9394810325579653	[598]	[163,170]	-8	hSpCas9	negative selection	895305
86254724	86254747	2	+	26627737	GBM cells	viability after 5 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.1892170353929793	[134]	[41,84]	-3	hSpCas9	negative selection	895306
86263951	86263974	2	+	26627737	GBM cells	viability after 5 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.1806422996549697	[670]	[299,334]	-3	hSpCas9	negative selection	895307
86338040	86338063	2	-	26627737	GBM cells	viability after 5 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.01395238315190206	[252]	[146,126]	0	hSpCas9	negative selection	895308
86217039	86217062	2	+	26627737	GBM cells	viability after 13 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.352195155250589	[335]	[208,251]	4	hSpCas9	negative selection	977618
86232665	86232688	2	+	26627737	GBM cells	viability after 13 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.262834927985191	[82]	[101,112]	9	hSpCas9	negative selection	977619
86251977	86252000	2	-	26627737	GBM cells	viability after 13 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.8193065212567312	[598]	[208,163]	-7	hSpCas9	negative selection	977620
86254724	86254747	2	+	26627737	GBM cells	viability after 13 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.037637907993750774	[134]	[99,54]	0	hSpCas9	negative selection	977621
86263951	86263974	2	+	26627737	GBM cells	viability after 13 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.11187032216594361	[670]	[353,322]	-1	hSpCas9	negative selection	977622
86338040	86338063	2	-	26627737	GBM cells	viability after 13 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.11991462526347328	[252]	[141,154]	1	hSpCas9	negative selection	977623
86217039	86217062	2	+	26627737	GBM cells	viability after 21 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.43608839959600354	[335]	[235,256]	4	hSpCas9	negative selection	1059933
86232665	86232688	2	+	26627737	GBM cells	viability after 21 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.0203680388330274	[82]	[103,79]	8	hSpCas9	negative selection	1059934
86251977	86252000	2	-	26627737	GBM cells	viability after 21 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-1.29608840257813	[598]	[131,132]	-8	hSpCas9	negative selection	1059935
86254724	86254747	2	+	26627737	GBM cells	viability after 21 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.19583108937816374	[134]	[74,53]	-2	hSpCas9	negative selection	1059936
86263951	86263974	2	+	26627737	GBM cells	viability after 21 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.0866096095146307	[670]	[347,338]	-1	hSpCas9	negative selection	1059937
86338040	86338063	2	-	26627737	GBM cells	viability after 21 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.03849538353239071	[252]	[148,133]	0	hSpCas9	negative selection	1059938
86217039	86217062	2	+	26627737	RPE1	viability after 9 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.19892608310336057	[1693]	[637,570]	1	hSpCas9	negative selection	1142248
86232665	86232688	2	+	26627737	RPE1	viability after 9 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.3662989427239518	[639]	[154,155]	-3	hSpCas9	negative selection	1142249
86251977	86252000	2	-	26627737	RPE1	viability after 9 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.9070945592728639	[2179]	[490,199]	-6	hSpCas9	negative selection	1142250
86254724	86254747	2	+	26627737	RPE1	viability after 9 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.7009119627398679	[347]	[163,193]	4	hSpCas9	negative selection	1142251
86263951	86263974	2	+	26627737	RPE1	viability after 9 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.20040498015087915	[2503]	[929,862]	1	hSpCas9	negative selection	1142252
86338040	86338063	2	-	26627737	RPE1	viability after 9 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.6962977821787418	[475]	[254,223]	4	hSpCas9	negative selection	1142253
86217039	86217062	2	+	26627737	RPE1	viability after 12 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.2823699942863418	[1693]	[638,462]	2	hSpCas9	negative selection	1224563
86232665	86232688	2	+	26627737	RPE1	viability after 12 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.33478447014363755	[639]	[330,95]	2	hSpCas9	negative selection	1224564
86251977	86252000	2	-	26627737	RPE1	viability after 12 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-1.1207010121863206	[2179]	[297,238]	-6	hSpCas9	negative selection	1224565
86254724	86254747	2	+	26627737	RPE1	viability after 12 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.9095516686118459	[347]	[162,188]	5	hSpCas9	negative selection	1224566
86263951	86263974	2	+	26627737	RPE1	viability after 12 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.042463351466892396	[2503]	[643,662]	0	hSpCas9	negative selection	1224567
86338040	86338063	2	-	26627737	RPE1	viability after 12 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.7519767110845846	[475]	[125,309]	5	hSpCas9	negative selection	1224568
86217039	86217062	2	+	26627737	RPE1	viability after 15 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.22851015293875854	[1693]	[564,557]	1	hSpCas9	negative selection	1306878
86232665	86232688	2	+	26627737	RPE1	viability after 15 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.10328390387396019	[639]	[250,88]	0	hSpCas9	negative selection	1306879
86251977	86252000	2	-	26627737	RPE1	viability after 15 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.7162073941554897	[2179]	[410,340]	-4	hSpCas9	negative selection	1306880
86254724	86254747	2	+	26627737	RPE1	viability after 15 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.8511424381759547	[347]	[172,181]	5	hSpCas9	negative selection	1306881
86263951	86263974	2	+	26627737	RPE1	viability after 15 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.16948185071055466	[2503]	[845,748]	1	hSpCas9	negative selection	1306882
86338040	86338063	2	-	26627737	RPE1	viability after 15 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.3181601175680477	[475]	[174,160]	2	hSpCas9	negative selection	1306883
86217039	86217062	2	+	26627737	RPE1	viability after 18 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.18086544449062658	[1693]	[509,526]	1	hSpCas9	negative selection	1389193
86232665	86232688	2	+	26627737	RPE1	viability after 18 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.4660585725545367	[639]	[269,204]	3	hSpCas9	negative selection	1389194
86251977	86252000	2	-	26627737	RPE1	viability after 18 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.6853983208688731	[2179]	[564,152]	-4	hSpCas9	negative selection	1389195
86254724	86254747	2	+	26627737	RPE1	viability after 18 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.4606526553474546	[347]	[77,183]	3	hSpCas9	negative selection	1389196
86263951	86263974	2	+	26627737	RPE1	viability after 18 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.14311194474128786	[2503]	[810,676]	0	hSpCas9	negative selection	1389197
86338040	86338063	2	-	26627737	RPE1	viability after 18 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.55803321160825	[475]	[148,231]	3	hSpCas9	negative selection	1389198
86217039	86217062	2	+	26627737	HeLa	viability after 8 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.6624932400601601	[562]	[484,375,327]	6	hSpCas9	negative selection	1471508
86232665	86232688	2	+	26627737	HeLa	viability after 8 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.4317428640007945	[340]	[136,59,136]	-4	hSpCas9	negative selection	1471509
86251977	86252000	2	-	26627737	HeLa	viability after 8 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.5027463175774459	[590]	[413,19,162]	-5	hSpCas9	negative selection	1471510
86254724	86254747	2	+	26627737	HeLa	viability after 8 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.9402446168412357	[82]	[115,44,57]	7	hSpCas9	negative selection	1471511
86263951	86263974	2	+	26627737	HeLa	viability after 8 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.04773899024327255	[780]	[436,377,263]	0	hSpCas9	negative selection	1471512
86338040	86338063	2	-	26627737	HeLa	viability after 8 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.0645797819019618	[357]	[196,206,96]	0	hSpCas9	negative selection	1471513
86217039	86217062	2	+	26627737	HeLa	viability after 12 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7638318726944803	[562]	[200,390,587]	6	hSpCas9	negative selection	1553823
86232665	86232688	2	+	26627737	HeLa	viability after 12 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.09472145672904048	[340]	[195,138,118]	0	hSpCas9	negative selection	1553824
86251977	86252000	2	-	26627737	HeLa	viability after 12 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.11366900348175224	[590]	[143,242,285]	-1	hSpCas9	negative selection	1553825
86254724	86254747	2	+	26627737	HeLa	viability after 12 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.884839311286067	[82]	[215,75,95]	9	hSpCas9	negative selection	1553826
86263951	86263974	2	+	26627737	HeLa	viability after 12 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.388524137066381	[780]	[293,265,178]	-3	hSpCas9	negative selection	1553827
86338040	86338063	2	-	26627737	HeLa	viability after 12 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-1.176936184102738	[357]	[98,86,8]	-8	hSpCas9	negative selection	1553828
86217039	86217062	2	+	26627737	HeLa	viability after 15 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7248025258114176	[562]	[259,340,549]	6	hSpCas9	negative selection	1636138
86232665	86232688	2	+	26627737	HeLa	viability after 15 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.5562455577367482	[340]	[145,60,73]	-5	hSpCas9	negative selection	1636139
86251977	86252000	2	-	26627737	HeLa	viability after 15 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.5864928892240192	[590]	[478,100,513]	5	hSpCas9	negative selection	1636140
86254724	86254747	2	+	26627737	HeLa	viability after 15 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.8119364446291337	[82]	[253,43,50]	9	hSpCas9	negative selection	1636141
86263951	86263974	2	+	26627737	HeLa	viability after 15 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.22836734128005187	[780]	[145,359,312]	-2	hSpCas9	negative selection	1636142
86338040	86338063	2	-	26627737	HeLa	viability after 15 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-0.48306948434967756	[357]	[46,168,96]	-4	hSpCas9	negative selection	1636143
86217039	86217062	2	+	26627737	HeLa	viability after 18 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7405044757711333	[562]	[169,297,549]	6	hSpCas9	negative selection	1718453
86232665	86232688	2	+	26627737	HeLa	viability after 18 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.5512963204986623	[340]	[98,49,73]	-5	hSpCas9	negative selection	1718454
86251977	86252000	2	-	26627737	HeLa	viability after 18 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.5977441756481793	[590]	[324,85,513]	5	hSpCas9	negative selection	1718455
86254724	86254747	2	+	26627737	HeLa	viability after 18 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.8344389287820886	[82]	[175,33,50]	9	hSpCas9	negative selection	1718456
86263951	86263974	2	+	26627737	HeLa	viability after 18 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.21756577647921072	[780]	[105,292,312]	-2	hSpCas9	negative selection	1718457
86338040	86338063	2	-	26627737	HeLa	viability after 18 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-0.4951015347450828	[357]	[32,135,96]	-4	hSpCas9	negative selection	1718458
86217039	86217062	2	+	26627737	HCT116	viability after 6 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	2.4907918220603835	[597]	[1103,210]	9	hSpCas9	negative selection	1800768
86232665	86232688	2	+	26627737	HCT116	viability after 6 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.5831452767362715	[764]	[68,520]	7	hSpCas9	negative selection	1800769
86251977	86252000	2	-	26627737	HCT116	viability after 6 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-1.2743134758127348	[2561]	[297,93]	-6	hSpCas9	negative selection	1800770
86254724	86254747	2	+	26627737	HCT116	viability after 6 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.8621778151570392	[137]	[90,10]	5	hSpCas9	negative selection	1800771
86263951	86263974	2	+	26627737	HCT116	viability after 6 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.6931497042357345	[1020]	[254,261]	4	hSpCas9	negative selection	1800772
86338040	86338063	2	-	26627737	HCT116	viability after 6 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-0.6687937897201343	[720]	[147,28]	-4	hSpCas9	negative selection	1800773
86217039	86217062	2	+	26627737	HCT116	viability after 8 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.677486904913899	[411]	[469,325,295]	6	hSpCas9	negative selection	1883083
86232665	86232688	2	+	26627737	HCT116	viability after 8 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.33585675955948535	[195]	[111,118,176]	3	hSpCas9	negative selection	1883084
86251977	86252000	2	-	26627737	HCT116	viability after 8 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.1503648392666168	[604]	[402,290,415]	1	hSpCas9	negative selection	1883085
86254724	86254747	2	+	26627737	HCT116	viability after 8 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	2.1727551409327246	[34]	[64,68,125]	9	hSpCas9	negative selection	1883086
86263951	86263974	2	+	26627737	HCT116	viability after 8 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.11251601251529686	[667]	[347,369,473]	1	hSpCas9	negative selection	1883087
86338040	86338063	2	-	26627737	HCT116	viability after 8 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.012117163649617735	[241]	[143,158,100]	0	hSpCas9	negative selection	1883088
86217039	86217062	2	+	26627737	HCT116	viability after 9 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	1.4561312419313175	[597]	[479,404]	8	hSpCas9	negative selection	1965398
86232665	86232688	2	+	26627737	HCT116	viability after 9 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.27167891657166776	[764]	[109,215]	-2	hSpCas9	negative selection	1965399
86251977	86252000	2	-	26627737	HCT116	viability after 9 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.4735177534352062	[2561]	[342,610]	-3	hSpCas9	negative selection	1965400
86254724	86254747	2	+	26627737	HCT116	viability after 9 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.2008014534189302	[137]	[15,138]	7	hSpCas9	negative selection	1965401
86263951	86263974	2	+	26627737	HCT116	viability after 9 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.22960658272301682	[1020]	[322,160]	-1	hSpCas9	negative selection	1965402
86338040	86338063	2	-	26627737	HCT116	viability after 9 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-1.08292894390924	[720]	[91,89]	-6	hSpCas9	negative selection	1965403
86217039	86217062	2	+	26627737	HCT116	viability after 12 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7123565604237534	[411]	[392,316,349]	6	hSpCas9	negative selection	2047713
86232665	86232688	2	+	26627737	HCT116	viability after 12 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.0632267322992375	[195]	[216,109,315]	8	hSpCas9	negative selection	2047714
86251977	86252000	2	-	26627737	HCT116	viability after 12 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.012879725117435958	[604]	[296,259,405]	0	hSpCas9	negative selection	2047715
86254724	86254747	2	+	26627737	HCT116	viability after 12 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.0769565831267784	[34]	[20,39,56]	8	hSpCas9	negative selection	2047716
86263951	86263974	2	+	26627737	HCT116	viability after 12 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.035330186336685054	[667]	[365,288,421]	0	hSpCas9	negative selection	2047717
86338040	86338063	2	-	26627737	HCT116	viability after 12 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.12797598211518296	[241]	[138,100,175]	1	hSpCas9	negative selection	2047718
86217039	86217062	2	+	26627737	HCT116	viability after 15 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.46283836733268297	[411]	[485,286,225]	4	hSpCas9	negative selection	2130028
86232665	86232688	2	+	26627737	HCT116	viability after 15 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.020961612828708	[195]	[187,235,255]	8	hSpCas9	negative selection	2130029
86251977	86252000	2	-	26627737	HCT116	viability after 15 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.18010517946382876	[604]	[452,358,127]	-2	hSpCas9	negative selection	2130030
86254724	86254747	2	+	26627737	HCT116	viability after 15 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.8255429818044182	[34]	[58,61,90]	9	hSpCas9	negative selection	2130031
86263951	86263974	2	+	26627737	HCT116	viability after 15 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.06744769906096537	[667]	[377,291,428]	0	hSpCas9	negative selection	2130032
86338040	86338063	2	-	26627737	HCT116	viability after 15 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.5123133324846639	[241]	[234,151,211]	5	hSpCas9	negative selection	2130033
86217039	86217062	2	+	26627737	HCT116	viability after 18 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7911259083558351	[411]	[441,261,334]	6	hSpCas9	negative selection	2212343
86232665	86232688	2	+	26627737	HCT116	viability after 18 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.8919900294423295	[195]	[89,129,316]	7	hSpCas9	negative selection	2212344
86251977	86252000	2	-	26627737	HCT116	viability after 18 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.15607834138389554	[604]	[409,288,278]	1	hSpCas9	negative selection	2212345
86254724	86254747	2	+	26627737	HCT116	viability after 18 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	1.4360454537070282	[34]	[51,11,76]	8	hSpCas9	negative selection	2212346
86263951	86263974	2	+	26627737	HCT116	viability after 18 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.03546399191568983	[667]	[262,244,447]	0	hSpCas9	negative selection	2212347
86338040	86338063	2	-	26627737	HCT116	viability after 18 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-0.12927803512550673	[241]	[92,128,96]	-1	hSpCas9	negative selection	2212348
86245838	86245861	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAAGCTCCGCCTCCCTGG	REEP1	ENSG00000068615	0.20407356943453547	[198,395]	[107,39]	1	dCas9-VP64	positive selection	2401929
86259213	86259236	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAATCTCTGCCTCCGAG	REEP1	ENSG00000068615	0.009160240507729789	[175,457]	[15,128]	0	dCas9-VP64	positive selection	2425911
86277276	86277299	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCAAG	REEP1	ENSG00000068615	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430165
86337786	86337809	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCTGGCCCCCGGCTGAAGGCGG	REEP1	ENSG00000068615	0.5423411498373576	[2,22]	[2,4]	2	dCas9-VP64	positive selection	2455194
86337734	86337757	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GATTGGGCGGTGAGCTGGTCAGG	REEP1	ENSG00000068615	2.3891369554459	[13,24]	[14,29]	7	dCas9-VP64	positive selection	2455195
86337826	86337849	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGGCGGGGCCGGTGCCCCGGG	REEP1	ENSG00000068615	-2.214421205102587	[77,97]	[5,0]	-9	dCas9-VP64	positive selection	2455196
86318678	86318701	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACTGCACCCGGCCGAG	REEP1	ENSG00000068615	1.1797326428655701	[26,26]	[14,10]	4	dCas9-VP64	positive selection	2469471
86245838	86245861	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAAGCTCCGCCTCCCTGG	REEP1	ENSG00000068615	4.4236004262517	[85,230]	[22,2123]	9	dCas9-VP64	positive selection	2497184
86259213	86259236	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAATCTCTGCCTCCGAG	REEP1	ENSG00000068615	0.1118552473866502	[131,312]	[53,99]	0	dCas9-VP64	positive selection	2521166
86277276	86277299	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCAAG	REEP1	ENSG00000068615	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525420
86337786	86337809	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCTGGCCCCCGGCTGAAGGCGG	REEP1	ENSG00000068615	0.48816518369630924	[3,14]	[2,4]	4	dCas9-VP64	positive selection	2550449
86337734	86337757	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GATTGGGCGGTGAGCTGGTCAGG	REEP1	ENSG00000068615	0.17842565695845214	[42,7]	[16,1]	1	dCas9-VP64	positive selection	2550450
86337826	86337849	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGGCGGGGCCGGTGCCCCGGG	REEP1	ENSG00000068615	0.4204371826741878	[64,62]	[15,37]	3	dCas9-VP64	positive selection	2550451
86318678	86318701	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACTGCACCCGGCCGAG	REEP1	ENSG00000068615	0.8568341606696415	[42,16]	[22,11]	6	dCas9-VP64	positive selection	2564726
86263952	86263975	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.00018290943657270353	[3,3]	[2,2]	0	hSpCas9	positive selection	3016268
86337494	86337517	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	-0.4256176449495682	[3,3]	[2,1]	-6	hSpCas9	positive selection	3016269
86282199	86282222	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	-1.0999595558321325	[3,3]	[1,0]	-9	hSpCas9	positive selection	3016270
86232773	86232796	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	-0.39974479085422504	[3,2]	[2,0]	-5	hSpCas9	positive selection	3016271
86263952	86263975	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.46111225693290014	[3,3]	[1,0]	-6	hSpCas9	positive selection	3084126
86337494	86337517	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	-0.6355871331126526	[3,3]	[3,0]	-8	hSpCas9	positive selection	3084127
86282199	86282222	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	-0.3803406024055871	[3,3]	[3,0]	-5	hSpCas9	positive selection	3084128
86232773	86232796	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	-0.29024400419738494	[3,3]	[2,1]	-4	hSpCas9	positive selection	3084129
86338030	86338053		-	24336571	A375	resistance to PLX after 7 days	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.15484893408916578	[9,9]	[9,7]	-5	hSpCas9	positive selection	3140383
86282199	86282222		-	24336571	A375	resistance to PLX after 7 days	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.022568012270827165	[37,39]	[39,38]	0	hSpCas9	positive selection	3140384
86232770	86232793		+	24336571	A375	resistance to PLX after 7 days	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.12886919505730354	[31,33]	[27,31]	-4	hSpCas9	positive selection	3140385
86232672	86232695		-	24336571	A375	resistance to PLX after 7 days	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.026933180137265367	[17,14]	[16,16]	1	hSpCas9	positive selection	3140386
86263964	86263987		-	24336571	A375	resistance to PLX after 7 days	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	-0.13846248363540337	[36,31]	[30,30]	-4	hSpCas9	positive selection	3140387
86232624	86232647		-	24336571	A375	resistance to PLX after 7 days	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	0.17541190734939205	[30,33]	[38,34]	5	hSpCas9	positive selection	3140388
86338030	86338053		-	24336571	A375	resistance to PLX after 14 days	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	1.18177825321976	[8,10]	[8,11]	8	hSpCas9	positive selection	3198176
86282199	86282222		-	24336571	A375	resistance to PLX after 14 days	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.4367786383191301	[37,44]	[12,14]	-5	hSpCas9	positive selection	3198177
86232770	86232793		+	24336571	A375	resistance to PLX after 14 days	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.04364947110511963	[36,32]	[15,15]	0	hSpCas9	positive selection	3198178
86232672	86232695		-	24336571	A375	resistance to PLX after 14 days	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.5529529265434033	[17,14]	[4,4]	-6	hSpCas9	positive selection	3198179
86263964	86263987		-	24336571	A375	resistance to PLX after 14 days	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	-0.841480779756839	[34,37]	[8,8]	-8	hSpCas9	positive selection	3198180
86232624	86232647		-	24336571	A375	resistance to PLX after 14 days	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	-0.40337729986671234	[30,33]	[11,10]	-5	hSpCas9	positive selection	3198181
86338030	86338053		-	24336571	A375	viability after 7 days	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.38143185326044593	[13]	[9,9]	-5	hSpCas9	negative selection	3255969
86282199	86282222		-	24336571	A375	viability after 7 days	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.03118061850421472	[39]	[37,39]	0	hSpCas9	negative selection	3255970
86232770	86232793		+	24336571	A375	viability after 7 days	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.32714224599694863	[42]	[31,33]	-5	hSpCas9	negative selection	3255971
86232672	86232695		-	24336571	A375	viability after 7 days	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.40894675553704124	[12]	[17,14]	6	hSpCas9	negative selection	3255972
86263964	86263987		-	24336571	A375	viability after 7 days	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	0.6059882824509741	[23]	[36,31]	8	hSpCas9	negative selection	3255973
86232624	86232647		-	24336571	A375	viability after 7 days	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	-0.004437182989018629	[33]	[30,33]	0	hSpCas9	negative selection	3255974
86338030	86338053		-	24336571	A375	viability after 14 days	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.3424116203462474	[13]	[8,10]	-4	hSpCas9	negative selection	3313762
86282199	86282222		-	24336571	A375	viability after 14 days	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.13377001310408798	[39]	[37,44]	1	hSpCas9	negative selection	3313763
86232770	86232793		+	24336571	A375	viability after 14 days	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.21644526796219798	[42]	[36,32]	-3	hSpCas9	negative selection	3313764
86232672	86232695		-	24336571	A375	viability after 14 days	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.3910340662836782	[12]	[17,14]	5	hSpCas9	negative selection	3313765
86263964	86263987		-	24336571	A375	viability after 14 days	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	0.6975938743826346	[23]	[34,37]	8	hSpCas9	negative selection	3313766
86232624	86232647		-	24336571	A375	viability after 14 days	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	0.018171205081450648	[33]	[30,33]	0	hSpCas9	negative selection	3313767
86338030	86338053	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-1.2425196756373702	[361,361]	[0,0]	-7	hSpCas9	positive selection	3389435
86282231	86282254	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	-0.5818775766511088	[228,228]	[0,0]	-4	hSpCas9	positive selection	3389436
86337469	86337492	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	-1.1392785697360233	[336,336]	[0,0]	-7	hSpCas9	positive selection	3389437
86263951	86263974	2	+	26780180	HT29	viability (Avana library 4 designs)	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.832094380674025	[]	[]	3	hSpCas9	negative selection	3454579
86337493	86337516	2	+	26780180	HT29	viability (Avana library 4 designs)	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	1.99685499718672	[]	[]	7	hSpCas9	negative selection	3454580
86282198	86282221	2	+	26780180	HT29	viability (Avana library 4 designs)	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	2.92244226037609	[]	[]	8	hSpCas9	negative selection	3454581
86232773	86232796	2	-	26780180	HT29	viability (Avana library 4 designs)	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	2.63949212410306	[]	[]	8	hSpCas9	negative selection	3454582
86263951	86263974	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-1.43219555739753	[]	[]	-2	hSpCas9	negative selection	3552010
86282198	86282221	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	-5.33334712614205	[]	[]	-5	hSpCas9	negative selection	3552011
86337493	86337516	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	-4.99152320124169	[]	[]	-5	hSpCas9	negative selection	3552012
86232773	86232796	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	5.44103118119963	[]	[]	8	hSpCas9	negative selection	3552013
86282199	86282222	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	2.3777916870202	[]	[]	3	hSpCas9	negative selection	3552014
86282184	86282207	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACAAGGCTGTGAAATCAAAGG	REEP1	ENSG00000068615	0.944526618253112	[]	[]	1	hSpCas9	negative selection	3552015
86263951	86263974	2	+	26780180	A375	viability (Avana lentiGuide)	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	13.0209374689425	[]	[]	7	hSpCas9	negative selection	3660669
86282198	86282221	2	+	26780180	A375	viability (Avana lentiGuide)	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	3.70759387802812	[]	[]	3	hSpCas9	negative selection	3660670
86337493	86337516	2	+	26780180	A375	viability (Avana lentiGuide)	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	9.52902594074387	[]	[]	6	hSpCas9	negative selection	3660671
86232773	86232796	2	-	26780180	A375	viability (Avana lentiGuide)	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	-4.15445442808828	[]	[]	-7	hSpCas9	negative selection	3660672
86282199	86282222	2	-	26780180	A375	viability (Avana lentiGuide)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-2.45970568921974	[]	[]	-4	hSpCas9	negative selection	3660673
86282184	86282207	2	-	26780180	A375	viability (Avana lentiGuide)	CTACAAGGCTGTGAAATCAAAGG	REEP1	ENSG00000068615	-6.66144955671556	[]	[]	-9	hSpCas9	negative selection	3660674
86263951	86263974	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.4233531510825793	[4]	[3,2]	-6	hSpCas9	positive selection	3769276
86282198	86282221	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	-0.45917011711117306	[4]	[4,1]	-6	hSpCas9	positive selection	3769277
86337493	86337516	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	-0.650552144834801	[6]	[4,2]	-7	hSpCas9	positive selection	3769278
86232773	86232796	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.23275061810461473	[5]	[6,5]	6	hSpCas9	positive selection	3769279
86282199	86282222	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.1002659488448035	[5]	[4,4]	-2	hSpCas9	positive selection	3769280
86282184	86282207	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACAAGGCTGTGAAATCAAAGG	REEP1	ENSG00000068615	-0.050472337242524985	[5]	[6,3]	-1	hSpCas9	positive selection	3769281
86263951	86263974	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.07865599418302804	[4]	[5,3]	1	hSpCas9	positive selection	3877883
86282198	86282221	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTGTAGGAATAATACGCAGG	REEP1	ENSG00000068615	-0.9393576098301717	[5]	[2,1]	-8	hSpCas9	positive selection	3877884
86337493	86337516	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGATCCATGACACCATGGCGG	REEP1	ENSG00000068615	-0.06187812006127459	[6]	[5,4]	-1	hSpCas9	positive selection	3877885
86232773	86232796	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.16864873807678119	[4]	[4,3]	4	hSpCas9	positive selection	3877886
86282199	86282222	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.19535080356071433	[5]	[4,5]	5	hSpCas9	positive selection	3877887
86282184	86282207	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACAAGGCTGTGAAATCAAAGG	REEP1	ENSG00000068615	0.5329011865407418	[4]	[6,5]	9	hSpCas9	positive selection	3877888
86232665	86232688	2	+	26780180	A375	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.916279968632771	[]	[]	4	hSpCas9	negative selection	3988254
86338030	86338053	2	-	26780180	A375	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	1.31114970617898	[]	[]	7	hSpCas9	negative selection	3988255
86282199	86282222	2	-	26780180	A375	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	1.4059799685252	[]	[]	7	hSpCas9	negative selection	3988256
86282231	86282254	2	-	26780180	A375	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.450705304907586	[]	[]	1	hSpCas9	negative selection	3988257
86232770	86232793	2	+	26780180	A375	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.42649537185056	[]	[]	1	hSpCas9	negative selection	3988258
86337469	86337492	2	+	26780180	A375	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.539653384393292	[]	[]	1	hSpCas9	negative selection	3988259
86232665	86232688	2	+	26780180	HT29	viability (GeCKOv2 library)	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.31973261724582	[]	[]	6	hSpCas9	negative selection	4096220
86338030	86338053	2	-	26780180	HT29	viability (GeCKOv2 library)	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	1.80360149866561	[]	[]	8	hSpCas9	negative selection	4096221
86282199	86282222	2	-	26780180	HT29	viability (GeCKOv2 library)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.95111761166881	[]	[]	4	hSpCas9	negative selection	4096222
86282231	86282254	2	-	26780180	HT29	viability (GeCKOv2 library)	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.513040638715791	[]	[]	1	hSpCas9	negative selection	4096223
86232770	86232793	2	+	26780180	HT29	viability (GeCKOv2 library)	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	1.15943909720093	[]	[]	5	hSpCas9	negative selection	4096224
86337469	86337492	2	+	26780180	HT29	viability (GeCKOv2 library)	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.246867312161319	[]	[]	0	hSpCas9	negative selection	4096225
86338030	86338053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	0.17517922792762256	[3]	[2,3]	4	hSpCas9	positive selection	4165807
86282199	86282222	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.1777562313420682	[5]	[4,3]	4	hSpCas9	positive selection	4165808
86232770	86232793	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.1197938790786186	[5]	[3,3]	3	hSpCas9	positive selection	4165809
86232672	86232695	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.19522770713357154	[4]	[2,2]	-4	hSpCas9	positive selection	4165810
86263964	86263987	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	0.05871300174831459	[4]	[2,3]	1	hSpCas9	positive selection	4165811
86232624	86232647	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	0.024230363202173588	[5]	[3,3]	0	hSpCas9	positive selection	4165812
86338030	86338053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.5096305563433362	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4229829
86282199	86282222	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	1.1655420382159232	[4]	[6,3,5,4]	8	hSpCas9	positive selection	4229830
86232770	86232793	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.7147637784819008	[5]	[3,3,4,3]	4	hSpCas9	positive selection	4229831
86232672	86232695	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	1.4806640456644478	[3]	[3,3,4,4]	9	hSpCas9	positive selection	4229832
86263964	86263987	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACAGACATCTTCCTTTGTTGG	REEP1	ENSG00000068615	1.0618385828349846	[4]	[4,4,4,3]	7	hSpCas9	positive selection	4229833
86232624	86232647	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGAGAGCGCTAGCAGCTCAGG	REEP1	ENSG00000068615	0.9945027324214606	[4]	[2,0,5,4]	7	hSpCas9	positive selection	4229834
86232770	86232793	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.2599192006793059	[3]	[2,1]	-5	hSpCas9	positive selection	4294407
86282199	86282222	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.09010502931002498	[3]	[3,1]	1	hSpCas9	positive selection	4294408
86232665	86232688	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.1957705935624466	[2]	[2,1]	4	hSpCas9	positive selection	4294409
86338030	86338053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	0.2571813781496391	[3]	[3,3]	5	hSpCas9	positive selection	4358663
86282231	86282254	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.8008782712064547	[2]	[3,4]	9	hSpCas9	positive selection	4358664
86337469	86337492	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.287083423260018	[3]	[2,3]	6	hSpCas9	positive selection	4358665
86232689	86232711	2	+	27760321	OCIAML3	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.6302978646559788	[932,717]	[783,1262]	7	hSpCas9	negative selection	4433949
86232771	86232793	2	+	27760321	OCIAML3	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.5013047529678061	[627,508]	[232,415]	-5	hSpCas9	negative selection	4433950
86232785	86232807	2	+	27760321	OCIAML3	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.619295336585217	[683,553]	[651,853]	7	hSpCas9	negative selection	4433951
86251989	86252011	2	-	27760321	OCIAML3	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.3582535000936631	[356,255]	[248,375]	4	hSpCas9	negative selection	4433952
86252002	86252024	2	-	27760321	OCIAML3	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	-0.05719891376468676	[469,423]	[247,449]	0	hSpCas9	negative selection	4433953
86254696	86254718	2	+	27760321	OCIAML3	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-0.5042683776327794	[143,156]	[73,95]	-5	hSpCas9	negative selection	4433954
86254721	86254743	2	+	27760321	OCIAML3	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.2542529907859278	[254,199]	[169,263]	3	hSpCas9	negative selection	4433955
86254741	86254763	2	+	27760321	OCIAML3	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.24413996725449288	[506,482]	[315,341]	-3	hSpCas9	negative selection	4433956
86263952	86263974	2	+	27760321	OCIAML3	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	1.2396424003602036	[84,67]	[126,157]	9	hSpCas9	negative selection	4433957
86264021	86264043	2	-	27760321	OCIAML3	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.038443226822945764	[293,257]	[240,168]	0	hSpCas9	negative selection	4433958
86282200	86282222	2	+	27760321	OCIAML3	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-0.6935041502645531	[44,34]	[13,25]	-6	hSpCas9	negative selection	4433959
86232689	86232711	2	+	27760321	OCIAML2	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.6147004384773528	[932,717]	[787,1313]	8	hSpCas9	negative selection	4517412
86232771	86232793	2	+	27760321	OCIAML2	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.1716622746624454	[627,508]	[406,404]	-2	hSpCas9	negative selection	4517413
86232785	86232807	2	+	27760321	OCIAML2	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.3426581664837358	[683,553]	[480,829]	4	hSpCas9	negative selection	4517414
86251989	86252011	2	-	27760321	OCIAML2	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.1209000118106861	[356,255]	[188,273]	-1	hSpCas9	negative selection	4517415
86252002	86252024	2	-	27760321	OCIAML2	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.3191341337228567	[469,423]	[388,531]	4	hSpCas9	negative selection	4517416
86254696	86254718	2	+	27760321	OCIAML2	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	0.048836237397840154	[143,156]	[134,115]	0	hSpCas9	negative selection	4517417
86254721	86254743	2	+	27760321	OCIAML2	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.5387263851832615	[254,199]	[243,293]	7	hSpCas9	negative selection	4517418
86254741	86254763	2	+	27760321	OCIAML2	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	0.23412922302148984	[506,482]	[487,449]	3	hSpCas9	negative selection	4517419
86263952	86263974	2	+	27760321	OCIAML2	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.12095014342998933	[84,67]	[34,84]	-1	hSpCas9	negative selection	4517420
86264021	86264043	2	-	27760321	OCIAML2	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	0.4509809681692193	[293,257]	[282,332]	6	hSpCas9	negative selection	4517421
86282200	86282222	2	+	27760321	OCIAML2	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-0.1391427041058595	[44,34]	[23,35]	-2	hSpCas9	negative selection	4517422
86232689	86232711	2	+	27760321	MV411	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.7318443603093353	[932,717]	[1134,541]	5	hSpCas9	negative selection	4600875
86232771	86232793	2	+	27760321	MV411	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.19090284421532577	[627,508]	[373,503]	1	hSpCas9	negative selection	4600876
86232785	86232807	2	+	27760321	MV411	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	-0.24845507330001107	[683,553]	[367,302]	-2	hSpCas9	negative selection	4600877
86251989	86252011	2	-	27760321	MV411	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	1.2212857832916162	[356,255]	[644,198]	8	hSpCas9	negative selection	4600878
86252002	86252024	2	-	27760321	MV411	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.8255750989086934	[469,423]	[614,382]	6	hSpCas9	negative selection	4600879
86254696	86254718	2	+	27760321	MV411	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	1.5824882153326671	[143,156]	[378,179]	9	hSpCas9	negative selection	4600880
86254721	86254743	2	+	27760321	MV411	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-1.3291397538470795	[254,199]	[4,140]	-7	hSpCas9	negative selection	4600881
86254741	86254763	2	+	27760321	MV411	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	0.11475537504111313	[506,482]	[537,77]	0	hSpCas9	negative selection	4600882
86263952	86263974	2	+	27760321	MV411	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	2.354907590454596	[84,67]	[426,0]	9	hSpCas9	negative selection	4600883
86264021	86264043	2	-	27760321	MV411	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.5866973672649106	[293,257]	[150,75]	-4	hSpCas9	negative selection	4600884
86282200	86282222	2	+	27760321	MV411	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-4.712148788839571	[44,34]	[0,0]	-9	hSpCas9	negative selection	4600885
86232689	86232711	2	+	27760321	HL60	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	-0.03881786876312998	[932,717]	[570,736]	0	hSpCas9	negative selection	4684338
86232771	86232793	2	+	27760321	HL60	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.5317359859198882	[627,508]	[220,423]	-5	hSpCas9	negative selection	4684339
86232785	86232807	2	+	27760321	HL60	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.7698825501682265	[683,553]	[810,906]	8	hSpCas9	negative selection	4684340
86251989	86252011	2	-	27760321	HL60	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.0735906491429611	[356,255]	[234,235]	-1	hSpCas9	negative selection	4684341
86252002	86252024	2	-	27760321	HL60	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.4103144692998551	[469,423]	[461,508]	5	hSpCas9	negative selection	4684342
86254696	86254718	2	+	27760321	HL60	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	0.3389862079857482	[143,156]	[108,206]	4	hSpCas9	negative selection	4684343
86254721	86254743	2	+	27760321	HL60	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-0.4880782949484116	[254,199]	[118,144]	-5	hSpCas9	negative selection	4684344
86254741	86254763	2	+	27760321	HL60	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	0.6208158982971984	[506,482]	[658,583]	7	hSpCas9	negative selection	4684345
86263952	86263974	2	+	27760321	HL60	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	2.252951301082664	[84,67]	[316,273]	9	hSpCas9	negative selection	4684346
86264021	86264043	2	-	27760321	HL60	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.09764332567954215	[293,257]	[185,235]	-1	hSpCas9	negative selection	4684347
86282200	86282222	2	+	27760321	HL60	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	0.0096667957216785	[44,34]	[4,61]	0	hSpCas9	negative selection	4684348
86232689	86232711	2	+	27760321	HT1080	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.6557756043959069	[717,559]	[348,457]	3	hSpCas9	negative selection	4767801
86232771	86232793	2	+	27760321	HT1080	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.8881815539702989	[508,396]	[101,587]	5	hSpCas9	negative selection	4767802
86232785	86232807	2	+	27760321	HT1080	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.25738466817671546	[553,432]	[150,326]	1	hSpCas9	negative selection	4767803
86251989	86252011	2	-	27760321	HT1080	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.7274636892882818	[255,199]	[72,34]	-3	hSpCas9	negative selection	4767804
86252002	86252024	2	-	27760321	HT1080	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.6507861915574871	[423,330]	[248,221]	3	hSpCas9	negative selection	4767805
86254696	86254718	2	+	27760321	HT1080	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	0.5138250113336502	[156,122]	[124,29]	2	hSpCas9	negative selection	4767806
86254721	86254743	2	+	27760321	HT1080	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-2.230288525503626	[199,155]	[27,0]	-6	hSpCas9	negative selection	4767807
86254741	86254763	2	+	27760321	HT1080	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	0.7492788155292467	[482,376]	[328,242]	4	hSpCas9	negative selection	4767808
86263952	86263974	2	+	27760321	HT1080	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-2.8310201923523306	[67,52]	[0,5]	-7	hSpCas9	negative selection	4767809
86264021	86264043	2	-	27760321	HT1080	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-2.2959232530260913	[257,201]	[0,37]	-6	hSpCas9	negative selection	4767810
86282200	86282222	2	+	27760321	HT1080	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-3.6516721609785625	[34,27]	[0,0]	-8	hSpCas9	negative selection	4767811
86232689	86232711	2	+	27760321	HT29	viability after 7 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.6378809981332267	[717,559]	[1630,1022,1230]	8	hSpCas9	negative selection	4851264
86232771	86232793	2	+	27760321	HT29	viability after 7 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.33524785839928	[508,396]	[809,702,701]	5	hSpCas9	negative selection	4851265
86232785	86232807	2	+	27760321	HT29	viability after 7 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.060057454593706816	[553,432]	[605,780,590]	0	hSpCas9	negative selection	4851266
86251989	86252011	2	-	27760321	HT29	viability after 7 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.3989728431474401	[255,199]	[468,319,381]	6	hSpCas9	negative selection	4851267
86252002	86252024	2	-	27760321	HT29	viability after 7 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	-0.026114981247065912	[423,330]	[505,594,336]	0	hSpCas9	negative selection	4851268
86254696	86254718	2	+	27760321	HT29	viability after 7 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.3197434521355063	[156,122]	[120,85,17]	-9	hSpCas9	negative selection	4851269
86254721	86254743	2	+	27760321	HT29	viability after 7 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.14591558906733004	[199,155]	[397,290,95]	2	hSpCas9	negative selection	4851270
86254741	86254763	2	+	27760321	HT29	viability after 7 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.2849005741071244	[482,376]	[533,379,457]	-4	hSpCas9	negative selection	4851271
86263952	86263974	2	+	27760321	HT29	viability after 7 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.33722227011860273	[67,52]	[138,48,111]	5	hSpCas9	negative selection	4851272
86264021	86264043	2	-	27760321	HT29	viability after 7 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	0.07575801330365373	[257,201]	[211,285,418]	1	hSpCas9	negative selection	4851273
86282200	86282222	2	+	27760321	HT29	viability after 7 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-1.5989527612208239	[34,27]	[4,21,11]	-9	hSpCas9	negative selection	4851274
86232689	86232711	2	+	27760321	HT29	viability after 25 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	-0.030726758914804586	[717,559]	[609,549,1021]	0	hSpCas9	negative selection	4934727
86232771	86232793	2	+	27760321	HT29	viability after 25 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.09619160308019178	[508,396]	[415,421,633]	-1	hSpCas9	negative selection	4934728
86232785	86232807	2	+	27760321	HT29	viability after 25 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.3068305400923752	[553,432]	[564,711,837]	3	hSpCas9	negative selection	4934729
86251989	86252011	2	-	27760321	HT29	viability after 25 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.08944513600135973	[255,199]	[155,312,273]	-1	hSpCas9	negative selection	4934730
86252002	86252024	2	-	27760321	HT29	viability after 25 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	-0.24019395664450044	[423,330]	[302,500,286]	-3	hSpCas9	negative selection	4934731
86254696	86254718	2	+	27760321	HT29	viability after 25 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-2.0636226571154253	[156,122]	[44,16,53]	-8	hSpCas9	negative selection	4934732
86254721	86254743	2	+	27760321	HT29	viability after 25 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-0.16934814752263172	[199,155]	[160,189,193]	-2	hSpCas9	negative selection	4934733
86254741	86254763	2	+	27760321	HT29	viability after 25 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.2967217163812588	[482,376]	[474,309,410]	-3	hSpCas9	negative selection	4934734
86263952	86263974	2	+	27760321	HT29	viability after 25 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.4810745678605284	[67,52]	[96,132,54]	5	hSpCas9	negative selection	4934735
86264021	86264043	2	-	27760321	HT29	viability after 25 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	0.14138542957550637	[257,201]	[264,281,327]	1	hSpCas9	negative selection	4934736
86282200	86282222	2	+	27760321	HT29	viability after 25 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	0.07147739497420469	[34,27]	[26,25,63]	0	hSpCas9	negative selection	4934737
86232689	86232711	2	+	27760321	HT29	viability after 22 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.34863286095901613	[717,559]	[1105,698,1012]	3	hSpCas9	negative selection	5018190
86232771	86232793	2	+	27760321	HT29	viability after 22 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.22710806099674136	[508,396]	[714,409,711]	2	hSpCas9	negative selection	5018191
86232785	86232807	2	+	27760321	HT29	viability after 22 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.5721975491173138	[553,432]	[919,976,643]	6	hSpCas9	negative selection	5018192
86251989	86252011	2	-	27760321	HT29	viability after 22 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.09497698190503945	[255,199]	[223,250,371]	0	hSpCas9	negative selection	5018193
86252002	86252024	2	-	27760321	HT29	viability after 22 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.5501413594431537	[423,330]	[741,556,614]	6	hSpCas9	negative selection	5018194
86254696	86254718	2	+	27760321	HT29	viability after 22 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-0.6883767261871081	[156,122]	[93,163,42]	-5	hSpCas9	negative selection	5018195
86254721	86254743	2	+	27760321	HT29	viability after 22 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.2235091521705096	[199,155]	[215,201,303]	2	hSpCas9	negative selection	5018196
86254741	86254763	2	+	27760321	HT29	viability after 22 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.5874538253075005	[482,376]	[291,425,274]	-5	hSpCas9	negative selection	5018197
86263952	86263974	2	+	27760321	HT29	viability after 22 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.4627682451344972	[67,52]	[40,115,133]	5	hSpCas9	negative selection	5018198
86264021	86264043	2	-	27760321	HT29	viability after 22 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.6887762989099202	[257,201]	[64,335,95]	-5	hSpCas9	negative selection	5018199
86282200	86282222	2	+	27760321	HT29	viability after 22 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-0.28857772287773553	[34,27]	[45,27,14]	-3	hSpCas9	negative selection	5018200
86232689	86232711	2	+	27760321	HT29	viability after 19 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.09446534767565518	[717,559]	[1010,510,839]	0	hSpCas9	negative selection	5101653
86232771	86232793	2	+	27760321	HT29	viability after 19 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.09077059044178964	[508,396]	[490,755,406]	0	hSpCas9	negative selection	5101654
86232785	86232807	2	+	27760321	HT29	viability after 19 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.19228725182961182	[553,432]	[735,565,641]	1	hSpCas9	negative selection	5101655
86251989	86252011	2	-	27760321	HT29	viability after 19 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.47470939039955873	[255,199]	[570,235,303]	5	hSpCas9	negative selection	5101656
86252002	86252024	2	-	27760321	HT29	viability after 19 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.4647699896984578	[423,330]	[395,553,807]	4	hSpCas9	negative selection	5101657
86254696	86254718	2	+	27760321	HT29	viability after 19 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.4954421261477968	[156,122]	[82,83,7]	-7	hSpCas9	negative selection	5101658
86254721	86254743	2	+	27760321	HT29	viability after 19 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.3431154822895355	[199,155]	[174,391,200]	3	hSpCas9	negative selection	5101659
86254741	86254763	2	+	27760321	HT29	viability after 19 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.0075241922670366	[482,376]	[672,415,400]	0	hSpCas9	negative selection	5101660
86263952	86263974	2	+	27760321	HT29	viability after 19 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.9563298461809122	[67,52]	[83,18,9]	-6	hSpCas9	negative selection	5101661
86264021	86264043	2	-	27760321	HT29	viability after 19 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.2684617790059184	[257,201]	[228,282,146]	-3	hSpCas9	negative selection	5101662
86282200	86282222	2	+	27760321	HT29	viability after 19 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	0.4274264517109412	[34,27]	[149,6,0]	4	hSpCas9	negative selection	5101663
86232689	86232711	2	+	27760321	HT29	viability after 16 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.5827140106964994	[717,559]	[1176,796,1254]	6	hSpCas9	negative selection	5185116
86232771	86232793	2	+	27760321	HT29	viability after 16 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.2614660462861789	[508,396]	[727,598,506]	3	hSpCas9	negative selection	5185117
86232785	86232807	2	+	27760321	HT29	viability after 16 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	-0.006668634053890954	[553,432]	[796,364,514]	0	hSpCas9	negative selection	5185118
86251989	86252011	2	-	27760321	HT29	viability after 16 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.31400896862911587	[255,199]	[244,294,76]	-3	hSpCas9	negative selection	5185119
86252002	86252024	2	-	27760321	HT29	viability after 16 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	-0.036093802350582134	[423,330]	[561,406,280]	0	hSpCas9	negative selection	5185120
86254696	86254718	2	+	27760321	HT29	viability after 16 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.38661803311152	[156,122]	[13,113,45]	-7	hSpCas9	negative selection	5185121
86254721	86254743	2	+	27760321	HT29	viability after 16 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.17310212176329953	[199,155]	[277,208,191]	1	hSpCas9	negative selection	5185122
86254741	86254763	2	+	27760321	HT29	viability after 16 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.0862401551291361	[482,376]	[447,374,537]	-1	hSpCas9	negative selection	5185123
86263952	86263974	2	+	27760321	HT29	viability after 16 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	1.5921342188352927	[67,52]	[112,262,225]	9	hSpCas9	negative selection	5185124
86264021	86264043	2	-	27760321	HT29	viability after 16 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	0.12727887249633674	[257,201]	[145,492,185]	1	hSpCas9	negative selection	5185125
86282200	86282222	2	+	27760321	HT29	viability after 16 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	0.35191162206050786	[34,27]	[22,46,62]	4	hSpCas9	negative selection	5185126
86232689	86232711	2	+	27760321	HT29	viability after 13 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.29800206236128624	[717,559]	[873,982,878]	4	hSpCas9	negative selection	5268579
86232771	86232793	2	+	27760321	HT29	viability after 13 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.32318690749906187	[508,396]	[335,414,503]	-4	hSpCas9	negative selection	5268580
86232785	86232807	2	+	27760321	HT29	viability after 13 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.24315585470746826	[553,432]	[671,752,611]	3	hSpCas9	negative selection	5268581
86251989	86252011	2	-	27760321	HT29	viability after 13 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.632374170520092	[255,199]	[49,151,301]	-6	hSpCas9	negative selection	5268582
86252002	86252024	2	-	27760321	HT29	viability after 13 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.14162827856526963	[423,330]	[597,418,434]	1	hSpCas9	negative selection	5268583
86254696	86254718	2	+	27760321	HT29	viability after 13 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.1372435671920962	[156,122]	[39,96,83]	-7	hSpCas9	negative selection	5268584
86254721	86254743	2	+	27760321	HT29	viability after 13 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	0.26866047169106744	[199,155]	[209,213,317]	3	hSpCas9	negative selection	5268585
86254741	86254763	2	+	27760321	HT29	viability after 13 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.01602278360558096	[482,376]	[497,455,523]	0	hSpCas9	negative selection	5268586
86263952	86263974	2	+	27760321	HT29	viability after 13 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.7638490185888902	[67,52]	[138,142,77]	8	hSpCas9	negative selection	5268587
86264021	86264043	2	-	27760321	HT29	viability after 13 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.1847491835066375	[257,201]	[168,257,274]	-2	hSpCas9	negative selection	5268588
86282200	86282222	2	+	27760321	HT29	viability after 13 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-0.4496998505739187	[34,27]	[52,11,15]	-5	hSpCas9	negative selection	5268589
86232689	86232711	2	+	27760321	HT29	viability after 10 days	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.8300793430322928	[717,559]	[973,1382,1885]	9	hSpCas9	negative selection	5352042
86232771	86232793	2	+	27760321	HT29	viability after 10 days	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.21883402984544226	[508,396]	[496,759,718]	3	hSpCas9	negative selection	5352043
86232785	86232807	2	+	27760321	HT29	viability after 10 days	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.49221549089551664	[553,432]	[962,719,911]	6	hSpCas9	negative selection	5352044
86251989	86252011	2	-	27760321	HT29	viability after 10 days	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.36445879464442693	[255,199]	[469,330,298]	5	hSpCas9	negative selection	5352045
86252002	86252024	2	-	27760321	HT29	viability after 10 days	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.4670101002373838	[423,330]	[466,685,798]	6	hSpCas9	negative selection	5352046
86254696	86254718	2	+	27760321	HT29	viability after 10 days	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.1693752143043685	[156,122]	[34,112,85]	-8	hSpCas9	negative selection	5352047
86254721	86254743	2	+	27760321	HT29	viability after 10 days	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-0.07136197865091809	[199,155]	[150,368,120]	-1	hSpCas9	negative selection	5352048
86254741	86254763	2	+	27760321	HT29	viability after 10 days	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	-0.12118735976002937	[482,376]	[403,617,462]	-2	hSpCas9	negative selection	5352049
86263952	86263974	2	+	27760321	HT29	viability after 10 days	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.9243949611542319	[67,52]	[220,67,138]	9	hSpCas9	negative selection	5352050
86264021	86264043	2	-	27760321	HT29	viability after 10 days	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.14724635805531483	[257,201]	[234,369,177]	-2	hSpCas9	negative selection	5352051
86282200	86282222	2	+	27760321	HT29	viability after 10 days	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	0.4958593307243757	[34,27]	[59,60,45]	6	hSpCas9	negative selection	5352052
86232689	86232711	2	+	27760321	MOLM13	viability	CCGCCCAGACCCCGGTGGTGGG	REEP1	ENSG00000068615	0.23431834915241379	[932,717]	[1016,140]	1	hSpCas9	negative selection	5435505
86232771	86232793	2	+	27760321	MOLM13	viability	CTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.2722773757950565	[627,508]	[429,122]	-2	hSpCas9	negative selection	5435506
86232785	86232807	2	+	27760321	MOLM13	viability	CGATAAGGCACCCTGTCCCTGG	REEP1	ENSG00000068615	0.24357593941786282	[683,553]	[400,419]	1	hSpCas9	negative selection	5435507
86251989	86252011	2	-	27760321	MOLM13	viability	GGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-1.103725707510425	[356,255]	[144,23]	-6	hSpCas9	negative selection	5435508
86252002	86252024	2	-	27760321	MOLM13	viability	CCTTGTGCACTTCGGGAAGCGG	REEP1	ENSG00000068615	0.6560507494545528	[469,423]	[510,299]	4	hSpCas9	negative selection	5435509
86254696	86254718	2	+	27760321	MOLM13	viability	TTTCTTTTGAAGATAGCGTGGG	REEP1	ENSG00000068615	-1.3622031559541612	[143,156]	[49,18]	-7	hSpCas9	negative selection	5435510
86254721	86254743	2	+	27760321	MOLM13	viability	TACAAACTTCCTGTACAGGAGG	REEP1	ENSG00000068615	-0.6301642006435905	[254,199]	[83,80]	-4	hSpCas9	negative selection	5435511
86254741	86254763	2	+	27760321	MOLM13	viability	GGCTGGAGCCTTTTGTGTAGGG	REEP1	ENSG00000068615	0.9966180344615027	[506,482]	[739,402]	7	hSpCas9	negative selection	5435512
86263952	86263974	2	+	27760321	MOLM13	viability	CTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	1.752800744203705	[84,67]	[48,225]	9	hSpCas9	negative selection	5435513
86264021	86264043	2	-	27760321	MOLM13	viability	GGTCAAATGGATGATGTACTGG	REEP1	ENSG00000068615	-0.30270437908092274	[293,257]	[179,79]	-2	hSpCas9	negative selection	5435514
86282200	86282222	2	+	27760321	MOLM13	viability	CTTGTAGGAATAATACGCAGGG	REEP1	ENSG00000068615	-4.486091976011975	[44,34]	[0,0]	-9	hSpCas9	negative selection	5435515
86337160	86337183	2	+	27661255	K562	viability	GACCGAGCTGAGGAACAAAGCGG	REEP1	ENSG00000068615	0.17912903729704888	[1595,1824]	[1627,1470]	6	dCas9-KRAB	negative selection	5506828
86337666	86337689	2	+	27661255	K562	viability	GCAGCCGCGGCACGTTCTGGCGG	REEP1	ENSG00000068615	-0.08083393207756862	[292,339]	[259,219]	-3	dCas9-KRAB	negative selection	5506829
86337204	86337227	2	-	27661255	K562	viability	GGCGCTCGGGGGTTCCGTGGGGG	REEP1	ENSG00000068615	0.3542868394947176	[617,522]	[640,535]	9	dCas9-KRAB	negative selection	5506830
86337614	86337637	2	-	27661255	K562	viability	GGGCGCGCTCAGTCTGGCGGCGG	REEP1	ENSG00000068615	0.07609469964418392	[1282,1316]	[1260,951]	2	dCas9-KRAB	negative selection	5506831
86337670	86337693	2	-	27661255	K562	viability	GCCGCCGCCAGAACGTGCCGCGG	REEP1	ENSG00000068615	0.133642770727334	[79,111]	[108,61]	4	dCas9-KRAB	negative selection	5506832
86232770	86232793	2	+	27260156	BXPC3	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.19609927500412844	[592]	[649,615,613,1002]	4	hSpCas9	negative selection	5566867
86282199	86282222	2	-	27260156	BXPC3	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.13880221486248914	[580]	[425,463,638,714]	-3	hSpCas9	negative selection	5566868
86232665	86232688	2	+	27260156	BXPC3	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.06195905712664662	[233]	[217,234,228,354]	1	hSpCas9	negative selection	5566869
86338030	86338053	2	-	27260156	BXPC3	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.05172339753666	[962]	[887,928,863,1240]	-1	hSpCas9	negative selection	5631123
86282231	86282254	2	-	27260156	BXPC3	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.3972124422190337	[381]	[601,415,620,451]	8	hSpCas9	negative selection	5631124
86337469	86337492	2	+	27260156	BXPC3	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.3425977044710573	[646]	[815,781,810,1047]	7	hSpCas9	negative selection	5631125
86232770	86232793	2	+	27260156	A673	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.09872338864312541	[592]	[834,735,661,828]	2	hSpCas9	negative selection	5688118
86282199	86282222	2	-	27260156	A673	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.09183115218671331	[580]	[790,646,556,637]	-2	hSpCas9	negative selection	5688119
86232665	86232688	2	+	27260156	A673	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.16634097577555262	[233]	[314,271,304,372]	4	hSpCas9	negative selection	5688120
86338030	86338053	2	-	27260156	A673	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.08205538875102836	[962]	[1093,1125,1009,1139]	-2	hSpCas9	negative selection	5752374
86282231	86282254	2	-	27260156	A673	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4041631596749452	[381]	[664,534,643,589]	8	hSpCas9	negative selection	5752375
86337469	86337492	2	+	27260156	A673	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.1551884627092628	[646]	[944,855,943,713]	3	hSpCas9	negative selection	5752376
86232770	86232793	2	+	27260156	A375	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.16484306435784002	[592]	[605,603,602,649]	-2	hSpCas9	negative selection	5809369
86282199	86282222	2	-	27260156	A375	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.19777834493342306	[580]	[1103,909,505,628]	3	hSpCas9	negative selection	5809370
86232665	86232688	2	+	27260156	A375	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.7507479564027477	[233]	[420,599,394,442]	9	hSpCas9	negative selection	5809371
86338030	86338053	2	-	27260156	A375	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	0.09542796126449349	[962]	[1034,1780,1201,899]	1	hSpCas9	negative selection	5873625
86282231	86282254	2	-	27260156	A375	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.6927006307015066	[381]	[785,881,712,544]	8	hSpCas9	negative selection	5873626
86337469	86337492	2	+	27260156	A375	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.42933666510794843	[646]	[1059,1037,790,1162]	6	hSpCas9	negative selection	5873627
86232770	86232793	2	+	27260156	COLO741	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.12325113445933958	[592]	[738,487,849]	-3	hSpCas9	negative selection	5930620
86282199	86282222	2	-	27260156	COLO741	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.023460880195509626	[580]	[824,776,604]	0	hSpCas9	negative selection	5930621
86232665	86232688	2	+	27260156	COLO741	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.11899002211055021	[233]	[292,356,320]	2	hSpCas9	negative selection	5930622
86338030	86338053	2	-	27260156	COLO741	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.19262568317915074	[962]	[1168,1084,987]	-4	hSpCas9	negative selection	5994876
86282231	86282254	2	-	27260156	COLO741	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.14670103064012174	[381]	[535,620,467]	3	hSpCas9	negative selection	5994877
86337469	86337492	2	+	27260156	COLO741	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.2842712574405015	[646]	[990,1302,742]	6	hSpCas9	negative selection	5994878
86232770	86232793	2	+	27260156	CAL120	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.3046801551207766	[592]	[769,504,543]	-4	hSpCas9	negative selection	6051871
86282199	86282222	2	-	27260156	CAL120	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.012345590912855198	[580]	[1061,536,639]	0	hSpCas9	negative selection	6051872
86232665	86232688	2	+	27260156	CAL120	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.047315329311766297	[233]	[552,170,217]	0	hSpCas9	negative selection	6051873
86338030	86338053	2	-	27260156	CAL120	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.31879345684810123	[962]	[994,1096,797]	-5	hSpCas9	negative selection	6116127
86282231	86282254	2	-	27260156	CAL120	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4719620487834011	[381]	[588,433,938]	7	hSpCas9	negative selection	6116128
86337469	86337492	2	+	27260156	CAL120	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.19091814995250023	[646]	[935,832,988]	3	hSpCas9	negative selection	6116129
86232770	86232793	2	+	27260156	CADOES1	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.34989336717857844	[592]	[420,475,429,402]	-6	hSpCas9	negative selection	6173122
86282199	86282222	2	-	27260156	CADOES1	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.3021588637007333	[580]	[579,618,726,741]	5	hSpCas9	negative selection	6173123
86232665	86232688	2	+	27260156	CADOES1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.43803424305687544	[233]	[221,297,301,359]	7	hSpCas9	negative selection	6173124
86338030	86338053	2	-	27260156	CADOES1	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.0243979036245332	[962]	[858,793,844,1029]	0	hSpCas9	negative selection	6237378
86282231	86282254	2	-	27260156	CADOES1	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4618979390417356	[381]	[688,418,429,415]	7	hSpCas9	negative selection	6237379
86337469	86337492	2	+	27260156	CADOES1	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.40382649392785874	[646]	[842,906,577,858]	6	hSpCas9	negative selection	6237380
86232770	86232793	2	+	27260156	EWS502	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.31379860720874697	[592]	[398,366,665,615]	-5	hSpCas9	negative selection	6294373
86282199	86282222	2	-	27260156	EWS502	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.22027393810481322	[580]	[542,680,669,1013]	4	hSpCas9	negative selection	6294374
86232665	86232688	2	+	27260156	EWS502	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.5335566192653673	[233]	[411,394,407,199]	8	hSpCas9	negative selection	6294375
86338030	86338053	2	-	27260156	EWS502	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.06352184922831206	[962]	[756,834,1148,1210]	-1	hSpCas9	negative selection	6358629
86282231	86282254	2	-	27260156	EWS502	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.7150479399027507	[381]	[391,644,725,945]	9	hSpCas9	negative selection	6358630
86337469	86337492	2	+	27260156	EWS502	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.2623633412333235	[646]	[747,763,818,975]	4	hSpCas9	negative selection	6358631
86232770	86232793	2	+	27260156	EW8	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.009840821325376947	[592]	[510,493,382,565]	0	hSpCas9	negative selection	6415624
86282199	86282222	2	-	27260156	EW8	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.09370668792052339	[580]	[654,442,400,542]	1	hSpCas9	negative selection	6415625
86232665	86232688	2	+	27260156	EW8	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.002838937650989859	[233]	[197,160,202,195]	0	hSpCas9	negative selection	6415626
86338030	86338053	2	-	27260156	EW8	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.31437842614217193	[962]	[733,658,572,563]	-5	hSpCas9	negative selection	6479880
86282231	86282254	2	-	27260156	EW8	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.3810129053670958	[381]	[419,443,400,348]	7	hSpCas9	negative selection	6479881
86337469	86337492	2	+	27260156	EW8	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.492990906766119	[646]	[919,894,547,639]	8	hSpCas9	negative selection	6479882
86232770	86232793	2	+	27260156	CORL105	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.022325021508456278	[592]	[725,848,826,435]	0	hSpCas9	negative selection	6536875
86282199	86282222	2	-	27260156	CORL105	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.022206397313597193	[580]	[777,616,839,555]	0	hSpCas9	negative selection	6536876
86232665	86232688	2	+	27260156	CORL105	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.2615337019527073	[233]	[367,258,421,281]	5	hSpCas9	negative selection	6536877
86338030	86338053	2	-	27260156	CORL105	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.2953324075247	[962]	[922,764,1162,864]	-5	hSpCas9	negative selection	6601131
86282231	86282254	2	-	27260156	CORL105	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.25116697673097244	[381]	[546,505,614,474]	5	hSpCas9	negative selection	6601132
86337469	86337492	2	+	27260156	CORL105	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.27417528901049437	[646]	[947,928,974,821]	5	hSpCas9	negative selection	6601133
86232770	86232793	2	+	27260156	HS294T	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.4906480223768713	[592]	[172,488,298,337]	6	hSpCas9	negative selection	6658126
86282199	86282222	2	-	27260156	HS294T	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.03744761801112639	[580]	[168,225,204,346]	0	hSpCas9	negative selection	6658127
86232665	86232688	2	+	27260156	HS294T	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.7718868744970749	[233]	[91,123,236,174]	8	hSpCas9	negative selection	6658128
86338030	86338053	2	-	27260156	HS294T	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.3652529493032277	[962]	[187,287,400,287]	-5	hSpCas9	negative selection	6722382
86282231	86282254	2	-	27260156	HS294T	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.7676740336661061	[381]	[224,217,232,348]	8	hSpCas9	negative selection	6722383
86337469	86337492	2	+	27260156	HS294T	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.18667361593674403	[646]	[248,350,279,253]	2	hSpCas9	negative selection	6722384
86232770	86232793	2	+	27260156	HCC44	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.42243121094741687	[592]	[509,434,701,398]	-6	hSpCas9	negative selection	6779377
86282199	86282222	2	-	27260156	HCC44	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.18908882200361332	[580]	[634,611,1063,742]	3	hSpCas9	negative selection	6779378
86232665	86232688	2	+	27260156	HCC44	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.22314680315620095	[233]	[386,168,401,317]	3	hSpCas9	negative selection	6779379
86338030	86338053	2	-	27260156	HCC44	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.22587662711781697	[962]	[778,862,1093,1002]	-4	hSpCas9	negative selection	6843633
86282231	86282254	2	-	27260156	HCC44	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.0957258554453187	[381]	[681,394,387,396]	1	hSpCas9	negative selection	6843634
86337469	86337492	2	+	27260156	HCC44	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.20394763598800247	[646]	[875,847,841,801]	3	hSpCas9	negative selection	6843635
86232770	86232793	2	+	27260156	G402	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.41053541315780906	[592]	[814,759,297,362]	-5	hSpCas9	negative selection	6900628
86282199	86282222	2	-	27260156	G402	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.026244231568082477	[580]	[808,1073,427,517]	0	hSpCas9	negative selection	6900629
86232665	86232688	2	+	27260156	G402	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.35183274323103253	[233]	[637,181,193,465]	4	hSpCas9	negative selection	6900630
86338030	86338053	2	-	27260156	G402	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.707977411103383	[962]	[1177,457,641,650]	-7	hSpCas9	negative selection	6964884
86282231	86282254	2	-	27260156	G402	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.7279419437569443	[381]	[833,1374,400,530]	8	hSpCas9	negative selection	6964885
86337469	86337492	2	+	27260156	G402	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.19005395924046464	[646]	[924,996,739,943]	2	hSpCas9	negative selection	6964886
86232770	86232793	2	+	27260156	L33	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.3681328761934702	[592]	[840,301,446,769]	7	hSpCas9	negative selection	7021879
86282199	86282222	2	-	27260156	L33	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.04014080979936463	[580]	[657,204,275,787]	0	hSpCas9	negative selection	7021880
86232665	86232688	2	+	27260156	L33	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.07535941871182072	[233]	[259,99,158,228]	1	hSpCas9	negative selection	7021881
86338030	86338053	2	-	27260156	L33	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.43878821752433517	[962]	[765,283,438,682]	-8	hSpCas9	negative selection	7086135
86282231	86282254	2	-	27260156	L33	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.16612040821099264	[381]	[373,166,297,459]	3	hSpCas9	negative selection	7086136
86337469	86337492	2	+	27260156	L33	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.27717975047790133	[646]	[800,301,543,732]	6	hSpCas9	negative selection	7086137
86232770	86232793	2	+	27260156	K562	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.2618228694373044	[592]	[486,382,551,343]	-3	hSpCas9	negative selection	7143130
86282199	86282222	2	-	27260156	K562	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.09723634855032534	[580]	[459,752,343,391]	-1	hSpCas9	negative selection	7143131
86232665	86232688	2	+	27260156	K562	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.3637716692019787	[233]	[241,364,226,239]	4	hSpCas9	negative selection	7143132
86338030	86338053	2	-	27260156	K562	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.2553515810938003	[962]	[775,693,729,669]	-3	hSpCas9	negative selection	7207386
86282231	86282254	2	-	27260156	K562	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.9167226990539807	[381]	[592,708,728,537]	9	hSpCas9	negative selection	7207387
86337469	86337492	2	+	27260156	K562	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.3907735046204698	[646]	[661,472,1363,514]	5	hSpCas9	negative selection	7207388
86232770	86232793	2	+	27260156	HT29	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.21432542432152119	[592]	[851,830,1000,675]	4	hSpCas9	negative selection	7264381
86282199	86282222	2	-	27260156	HT29	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.09552547806976036	[580]	[749,680,844,732]	1	hSpCas9	negative selection	7264382
86232665	86232688	2	+	27260156	HT29	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.3803371124063514	[233]	[222,562,438,270]	7	hSpCas9	negative selection	7264383
86338030	86338053	2	-	27260156	HT29	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.40915693514634033	[962]	[1060,885,911,697]	-6	hSpCas9	negative selection	7328637
86282231	86282254	2	-	27260156	HT29	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4782684166473962	[381]	[866,671,685,406]	8	hSpCas9	negative selection	7328638
86337469	86337492	2	+	27260156	HT29	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.5177912730443108	[646]	[1240,1285,1101,915]	8	hSpCas9	negative selection	7328639
86232770	86232793	2	+	27260156	MHHES1	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.08115546072352797	[592]	[735,577,579,624]	-1	hSpCas9	negative selection	7385632
86282199	86282222	2	-	27260156	MHHES1	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.06819690075698692	[580]	[700,594,920,539]	1	hSpCas9	negative selection	7385633
86232665	86232688	2	+	27260156	MHHES1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.20347451349288437	[233]	[353,524,234,155]	4	hSpCas9	negative selection	7385634
86338030	86338053	2	-	27260156	MHHES1	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.28417402563219374	[962]	[918,800,1226,648]	-5	hSpCas9	negative selection	7449888
86282231	86282254	2	-	27260156	MHHES1	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4499777254270143	[381]	[777,710,487,431]	7	hSpCas9	negative selection	7449889
86337469	86337492	2	+	27260156	MHHES1	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.18588218043101323	[646]	[961,985,663,736]	3	hSpCas9	negative selection	7449890
86232770	86232793	2	+	27260156	MEWO	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.008801840946397022	[592]	[713,472,498]	0	hSpCas9	negative selection	7506883
86282199	86282222	2	-	27260156	MEWO	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.03911127307309087	[580]	[779,411,526]	0	hSpCas9	negative selection	7506884
86232665	86232688	2	+	27260156	MEWO	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.030872809283226	[233]	[281,199,173]	0	hSpCas9	negative selection	7506885
86338030	86338053	2	-	27260156	MEWO	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.016950280262546302	[962]	[977,897,811]	0	hSpCas9	negative selection	7571139
86282231	86282254	2	-	27260156	MEWO	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.37278127500445934	[381]	[457,513,414]	7	hSpCas9	negative selection	7571140
86337469	86337492	2	+	27260156	MEWO	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.036297527791253836	[646]	[661,630,576]	0	hSpCas9	negative selection	7571141
86232770	86232793	2	+	27260156	LNCAPCLONEFGC	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.25267138586820587	[592]	[472,672,763,668]	4	hSpCas9	negative selection	7628134
86282199	86282222	2	-	27260156	LNCAPCLONEFGC	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.3175013369202271	[580]	[536,750,648,680]	5	hSpCas9	negative selection	7628135
86232665	86232688	2	+	27260156	LNCAPCLONEFGC	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.15952157106246578	[233]	[257,179,376,155]	2	hSpCas9	negative selection	7628136
86338030	86338053	2	-	27260156	LNCAPCLONEFGC	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.0025768687005849333	[962]	[791,777,1138,820]	0	hSpCas9	negative selection	7692390
86282231	86282254	2	-	27260156	LNCAPCLONEFGC	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.5936616650321543	[381]	[421,547,665,473]	8	hSpCas9	negative selection	7692391
86337469	86337492	2	+	27260156	LNCAPCLONEFGC	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.5947903167923267	[646]	[745,929,1149,752]	8	hSpCas9	negative selection	7692392
86232770	86232793	2	+	27260156	PANC0327	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.17293124523873932	[592]	[585,696,454,622]	2	hSpCas9	negative selection	7749385
86282199	86282222	2	-	27260156	PANC0327	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.020631689148557564	[580]	[647,352,449,674]	0	hSpCas9	negative selection	7749386
86232665	86232688	2	+	27260156	PANC0327	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.15411768050539332	[233]	[367,233,200,132]	2	hSpCas9	negative selection	7749387
86338030	86338053	2	-	27260156	PANC0327	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.27512167165781964	[962]	[748,861,690,508]	-4	hSpCas9	negative selection	7813641
86282231	86282254	2	-	27260156	PANC0327	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.20105474659315742	[381]	[563,414,237,353]	3	hSpCas9	negative selection	7813642
86337469	86337492	2	+	27260156	PANC0327	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.7248070890350988	[646]	[895,1416,643,776]	9	hSpCas9	negative selection	7813643
86232770	86232793	2	+	27260156	NCIH2009	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.07844304521187573	[592]	[865,880,619]	-1	hSpCas9	negative selection	7870636
86282199	86282222	2	-	27260156	NCIH2009	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.14622161982472853	[580]	[1091,829,810]	2	hSpCas9	negative selection	7870637
86232665	86232688	2	+	27260156	NCIH2009	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.492436239317551	[233]	[360,375,623]	6	hSpCas9	negative selection	7870638
86338030	86338053	2	-	27260156	NCIH2009	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.36649975490861175	[962]	[1003,837,1282]	-5	hSpCas9	negative selection	7934892
86282231	86282254	2	-	27260156	NCIH2009	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.7898847140758707	[381]	[1003,1074,700]	9	hSpCas9	negative selection	7934893
86337469	86337492	2	+	27260156	NCIH2009	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.3806447090449395	[646]	[1169,1468,882]	5	hSpCas9	negative selection	7934894
86232770	86232793	2	+	27260156	NCIH1373	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.3791607218897372	[592]	[720,469,166,194]	-4	hSpCas9	negative selection	7991887
86282199	86282222	2	-	27260156	NCIH1373	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.22686049874140762	[580]	[497,678,528,128]	-2	hSpCas9	negative selection	7991888
86232665	86232688	2	+	27260156	NCIH1373	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.5474961615839522	[233]	[237,258,491,141]	5	hSpCas9	negative selection	7991889
86338030	86338053	2	-	27260156	NCIH1373	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.25322166812366287	[962]	[1182,907,731,219]	-3	hSpCas9	negative selection	8056143
86282231	86282254	2	-	27260156	NCIH1373	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	1.0710185493954727	[381]	[828,805,957,263]	9	hSpCas9	negative selection	8056144
86337469	86337492	2	+	27260156	NCIH1373	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.6022740544626868	[646]	[1225,1201,658,352]	6	hSpCas9	negative selection	8056145
86232770	86232793	2	+	27260156	PATU8902	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.41437892751040495	[592]	[1080,603,432,367]	-4	hSpCas9	negative selection	8113138
86282199	86282222	2	-	27260156	PATU8902	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.5587987877784107	[580]	[1148,1643,800,1277]	6	hSpCas9	negative selection	8113139
86232665	86232688	2	+	27260156	PATU8902	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.5505333093066042	[233]	[392,157,687,629]	6	hSpCas9	negative selection	8113140
86338030	86338053	2	-	27260156	PATU8902	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	0.13813712151901059	[962]	[1528,1685,1615,962]	1	hSpCas9	negative selection	8177394
86282231	86282254	2	-	27260156	PATU8902	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.4426519295399	[381]	[778,943,483,743]	4	hSpCas9	negative selection	8177395
86337469	86337492	2	+	27260156	PATU8902	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.5111461322111457	[646]	[1650,1345,846,1405]	5	hSpCas9	negative selection	8177396
86232770	86232793	2	+	27260156	PANC1	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.0217494753714772	[592]	[346,628,481,611]	0	hSpCas9	negative selection	8234389
86282199	86282222	2	-	27260156	PANC1	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.11199592731269661	[580]	[442,642,441,364]	-2	hSpCas9	negative selection	8234390
86232665	86232688	2	+	27260156	PANC1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.45040802693701665	[233]	[233,293,375,206]	7	hSpCas9	negative selection	8234391
86338030	86338053	2	-	27260156	PANC1	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.04422741335109426	[962]	[925,997,727,611]	0	hSpCas9	negative selection	8298645
86282231	86282254	2	-	27260156	PANC1	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.29653288428694174	[381]	[431,386,484,312]	5	hSpCas9	negative selection	8298646
86337469	86337492	2	+	27260156	PANC1	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.07683137233797788	[646]	[480,807,626,483]	1	hSpCas9	negative selection	8298647
86232770	86232793	2	+	27260156	PANC0813	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.14443280515137225	[592]	[819,653,849,759]	2	hSpCas9	negative selection	8355640
86282199	86282222	2	-	27260156	PANC0813	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.17608479931970744	[580]	[593,908,867,699]	3	hSpCas9	negative selection	8355641
86232665	86232688	2	+	27260156	PANC0813	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.2477207359365251	[233]	[282,320,351,343]	4	hSpCas9	negative selection	8355642
86338030	86338053	2	-	27260156	PANC0813	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.1823421983063881	[962]	[1119,1050,924,905]	-3	hSpCas9	negative selection	8419896
86282231	86282254	2	-	27260156	PANC0813	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.33388095343277313	[381]	[600,742,397,523]	5	hSpCas9	negative selection	8419897
86337469	86337492	2	+	27260156	PANC0813	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.2555996753531097	[646]	[942,847,1032,812]	4	hSpCas9	negative selection	8419898
86232770	86232793	2	+	27260156	RDES	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.2105976910235961	[592]	[464,453,688,809]	-4	hSpCas9	negative selection	8476891
86282199	86282222	2	-	27260156	RDES	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.12345537850959215	[580]	[516,566,735,649]	-2	hSpCas9	negative selection	8476892
86232665	86232688	2	+	27260156	RDES	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.4202173203084517	[233]	[316,281,426,433]	6	hSpCas9	negative selection	8476893
86338030	86338053	2	-	27260156	RDES	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.22765928739667474	[962]	[831,875,1076,1014]	-4	hSpCas9	negative selection	8541147
86282231	86282254	2	-	27260156	RDES	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.568382754699382	[381]	[528,608,770,722]	8	hSpCas9	negative selection	8541148
86337469	86337492	2	+	27260156	RDES	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.40778933571701625	[646]	[811,878,1041,1280]	6	hSpCas9	negative selection	8541149
86232770	86232793	2	+	27260156	PC3	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.18470216580387672	[592]	[374,768,932,780]	4	hSpCas9	negative selection	8598142
86282199	86282222	2	-	27260156	PC3	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.07093178697599198	[580]	[256,673,719,705]	-1	hSpCas9	negative selection	8598143
86232665	86232688	2	+	27260156	PC3	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.2255099850426584	[233]	[156,282,484,273]	5	hSpCas9	negative selection	8598144
86338030	86338053	2	-	27260156	PC3	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.4754803849422291	[962]	[352,710,1117,842]	-8	hSpCas9	negative selection	8662398
86282231	86282254	2	-	27260156	PC3	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.24664900597744743	[381]	[243,374,892,527]	5	hSpCas9	negative selection	8662399
86337469	86337492	2	+	27260156	PC3	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	-0.03242600719910993	[646]	[426,646,1193,489]	0	hSpCas9	negative selection	8662400
86232770	86232793	2	+	27260156	PATU8988T	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.1690240466247181	[592]	[672,697,615,590]	3	hSpCas9	negative selection	8719393
86282199	86282222	2	-	27260156	PATU8988T	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.13378852526340135	[580]	[438,572,549,487]	-2	hSpCas9	negative selection	8719394
86232665	86232688	2	+	27260156	PATU8988T	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.035291779543362045	[233]	[290,245,159,185]	0	hSpCas9	negative selection	8719395
86338030	86338053	2	-	27260156	PATU8988T	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	0.07965240102171123	[962]	[1101,993,866,971]	1	hSpCas9	negative selection	8783649
86282231	86282254	2	-	27260156	PATU8988T	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.19209321371453478	[381]	[436,587,233,447]	3	hSpCas9	negative selection	8783650
86337469	86337492	2	+	27260156	PATU8988T	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.3405252496817195	[646]	[1096,676,430,969]	6	hSpCas9	negative selection	8783651
86232770	86232793	2	+	27260156	T47D	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.09987610456980511	[592]	[698,559,545,786]	-2	hSpCas9	negative selection	8840644
86282199	86282222	2	-	27260156	T47D	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.24765205745443608	[580]	[801,765,840,807]	5	hSpCas9	negative selection	8840645
86232665	86232688	2	+	27260156	T47D	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.33827816468700256	[233]	[426,284,332,338]	7	hSpCas9	negative selection	8840646
86338030	86338053	2	-	27260156	T47D	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.1082734982192437	[962]	[1047,964,975,1185]	-2	hSpCas9	negative selection	8904900
86282231	86282254	2	-	27260156	T47D	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.45681163406039904	[381]	[590,519,604,738]	8	hSpCas9	negative selection	8904901
86337469	86337492	2	+	27260156	T47D	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.1193807619095254	[646]	[861,741,838,838]	2	hSpCas9	negative selection	8904902
86232770	86232793	2	+	27260156	SU8686	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	0.26134190293491194	[592]	[511,784,685,867]	4	hSpCas9	negative selection	8961895
86282199	86282222	2	-	27260156	SU8686	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.01483072743340419	[580]	[573,497,635,637]	0	hSpCas9	negative selection	8961896
86232665	86232688	2	+	27260156	SU8686	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.2531344933974613	[233]	[254,274,301,274]	4	hSpCas9	negative selection	8961897
86338030	86338053	2	-	27260156	SU8686	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.14904375219596222	[962]	[855,715,915,991]	-3	hSpCas9	negative selection	9026151
86282231	86282254	2	-	27260156	SU8686	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.44543616738760494	[381]	[468,368,453,842]	7	hSpCas9	negative selection	9026152
86337469	86337492	2	+	27260156	SU8686	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.19661276131578753	[646]	[710,744,730,751]	3	hSpCas9	negative selection	9026153
86232770	86232793	2	+	27260156	SKES1	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.01891453593781245	[592]	[728,524,523,566]	0	hSpCas9	negative selection	9083146
86282199	86282222	2	-	27260156	SKES1	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.006548158763187206	[580]	[545,663,619,487]	0	hSpCas9	negative selection	9083147
86232665	86232688	2	+	27260156	SKES1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.07694686689519448	[233]	[294,183,250,164]	-2	hSpCas9	negative selection	9083148
86338030	86338053	2	-	27260156	SKES1	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.13426344449152838	[962]	[1103,941,613,874]	-3	hSpCas9	negative selection	9147402
86282231	86282254	2	-	27260156	SKES1	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.23603594731129368	[381]	[403,542,481,374]	5	hSpCas9	negative selection	9147403
86337469	86337492	2	+	27260156	SKES1	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.15230959579157455	[646]	[790,880,585,643]	3	hSpCas9	negative selection	9147404
86232770	86232793	2	+	27260156	TOV112D	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.09252847622484323	[592]	[510,545,657,506]	-2	hSpCas9	negative selection	9204397
86282199	86282222	2	-	27260156	TOV112D	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	-0.2502313553774285	[580]	[552,576,395,457]	-5	hSpCas9	negative selection	9204398
86232665	86232688	2	+	27260156	TOV112D	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.05041798143189502	[233]	[241,324,191,172]	-1	hSpCas9	negative selection	9204399
86338030	86338053	2	-	27260156	TOV112D	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.2254424900323475	[962]	[762,1341,725,595]	-4	hSpCas9	negative selection	9268653
86282231	86282254	2	-	27260156	TOV112D	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.66737651336889	[381]	[473,993,461,583]	9	hSpCas9	negative selection	9268654
86337469	86337492	2	+	27260156	TOV112D	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	-0.012629503575193268	[646]	[735,714,713,434]	0	hSpCas9	negative selection	9268655
86232770	86232793	2	+	27260156	TC71	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.10972378753382939	[592]	[594,643,521,597]	-3	hSpCas9	negative selection	9325648
86282199	86282222	2	-	27260156	TC71	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.23622097485325133	[580]	[662,812,687,775]	6	hSpCas9	negative selection	9325649
86232665	86232688	2	+	27260156	TC71	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.059566480415632284	[233]	[227,299,261,255]	1	hSpCas9	negative selection	9325650
86338030	86338053	2	-	27260156	TC71	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.24363477571360126	[962]	[757,930,739,1077]	-6	hSpCas9	negative selection	9389904
86282231	86282254	2	-	27260156	TC71	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.5398036667832735	[381]	[625,579,598,573]	9	hSpCas9	negative selection	9389905
86337469	86337492	2	+	27260156	TC71	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.08348279408308223	[646]	[562,975,753,643]	2	hSpCas9	negative selection	9389906
86232770	86232793	2	+	27260156	TC32	viability	GCTCCGCAGTCTCTCCGATAAGG	REEP1	ENSG00000068615	-0.001138054084399931	[592]	[383,401,721,811]	0	hSpCas9	negative selection	9446899
86282199	86282222	2	-	27260156	TC32	viability	CCCTGCGTATTATTCCTACAAGG	REEP1	ENSG00000068615	0.18882849940186147	[580]	[484,475,948,675]	3	hSpCas9	negative selection	9446900
86232665	86232688	2	+	27260156	TC32	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.27272971447194094	[233]	[128,219,420,343]	5	hSpCas9	negative selection	9446901
86338030	86338053	2	-	27260156	TC32	viability	CAGACTGAAGAGGTTAGGTCTGG	REEP1	ENSG00000068615	-0.1412643798961296	[962]	[816,676,959,857]	-3	hSpCas9	negative selection	9511155
86282231	86282254	2	-	27260156	TC32	viability	CTTCCCTCCAGGCTTATATTTGG	REEP1	ENSG00000068615	0.3581148491973717	[381]	[400,365,603,512]	6	hSpCas9	negative selection	9511156
86337469	86337492	2	+	27260156	TC32	viability	GGCCACTTACACCACCAGCCTGG	REEP1	ENSG00000068615	0.1476636062972907	[646]	[687,435,968,702]	2	hSpCas9	negative selection	9511157
86217039	86217062	2	+	27869803	HPAFII	viability after 27 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.31670223026202615	[359]	[316,167,NaN]	2	hSpCas9	negative selection	9576048
86232665	86232688	2	+	27869803	HPAFII	viability after 27 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.337653015456816	[171]	[161,283,NaN]	9	hSpCas9	negative selection	9576049
86251977	86252000	2	-	27869803	HPAFII	viability after 27 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.9461267437757579	[630]	[121,213,NaN]	-6	hSpCas9	negative selection	9576050
86254724	86254747	2	+	27869803	HPAFII	viability after 27 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.4890992308952994	[93]	[58,77,NaN]	4	hSpCas9	negative selection	9576051
86263951	86263974	2	+	27869803	HPAFII	viability after 27 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.5778045032748722	[621]	[199,234,NaN]	-4	hSpCas9	negative selection	9576052
86338040	86338063	2	-	27869803	HPAFII	viability after 27 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.027525926265089554	[255]	[248,43,NaN]	0	hSpCas9	negative selection	9576053
86217039	86217062	2	+	27869803	HPAFII	viability after 15 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.5560363119533143	[359]	[923,347,NaN]	6	hSpCas9	negative selection	9658497
86232665	86232688	2	+	27869803	HPAFII	viability after 15 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.1279850627114723	[171]	[440,380,NaN]	9	hSpCas9	negative selection	9658498
86251977	86252000	2	-	27869803	HPAFII	viability after 15 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.855913685206275	[630]	[452,325,NaN]	-7	hSpCas9	negative selection	9658499
86254724	86254747	2	+	27869803	HPAFII	viability after 15 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.4040789809418628	[93]	[100,153,NaN]	4	hSpCas9	negative selection	9658500
86263951	86263974	2	+	27869803	HPAFII	viability after 15 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.6462708036342122	[621]	[563,341,NaN]	-6	hSpCas9	negative selection	9658501
86338040	86338063	2	-	27869803	HPAFII	viability after 15 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.012636027683705794	[255]	[464,160,NaN]	0	hSpCas9	negative selection	9658502
86217039	86217062	2	+	27869803	ASPC1	viability after 36 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.4676177550779833	[1022]	[619,503,391]	5	hSpCas9	negative selection	9740946
86232665	86232688	2	+	27869803	ASPC1	viability after 36 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.8112863664403158	[490]	[288,258,338]	7	hSpCas9	negative selection	9740947
86251977	86252000	2	-	27869803	ASPC1	viability after 36 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.9125791428779755	[1253]	[299,133,260]	-7	hSpCas9	negative selection	9740948
86254724	86254747	2	+	27869803	ASPC1	viability after 36 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.6343189857801133	[286]	[35,76,73]	-6	hSpCas9	negative selection	9740949
86263951	86263974	2	+	27869803	ASPC1	viability after 36 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.296828793345444	[1285]	[375,541,213]	-3	hSpCas9	negative selection	9740950
86338040	86338063	2	-	27869803	ASPC1	viability after 36 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.3568566116062766	[674]	[199,438,260]	3	hSpCas9	negative selection	9740951
86217039	86217062	2	+	27869803	PATU8988S	viability after 35 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	-0.16626146073988057	[761]	[268,277,NaN]	-2	hSpCas9	negative selection	9823395
86232665	86232688	2	+	27869803	PATU8988S	viability after 35 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.5998683941113874	[461]	[283,279,NaN]	6	hSpCas9	negative selection	9823396
86251977	86252000	2	-	27869803	PATU8988S	viability after 35 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	0.2652335755058628	[929]	[517,381,NaN]	3	hSpCas9	negative selection	9823397
86254724	86254747	2	+	27869803	PATU8988S	viability after 35 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.3937389089123067	[250]	[52,100,NaN]	-4	hSpCas9	negative selection	9823398
86263951	86263974	2	+	27869803	PATU8988S	viability after 35 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.17758891010123612	[1083]	[611,374,NaN]	2	hSpCas9	negative selection	9823399
86338040	86338063	2	-	27869803	PATU8988S	viability after 35 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	-0.13726686020850118	[508]	[139,232,NaN]	-1	hSpCas9	negative selection	9823400
86217039	86217062	2	+	27869803	PATU8988S	viability after 31 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.4204907574515809	[761]	[297,544,NaN]	5	hSpCas9	negative selection	9905844
86232665	86232688	2	+	27869803	PATU8988S	viability after 31 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.9295140166949549	[461]	[305,407,NaN]	9	hSpCas9	negative selection	9905845
86251977	86252000	2	-	27869803	PATU8988S	viability after 31 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.18177305030023938	[929]	[384,252,NaN]	-2	hSpCas9	negative selection	9905846
86254724	86254747	2	+	27869803	PATU8988S	viability after 31 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	-0.38890779821073407	[250]	[53,104,NaN]	-4	hSpCas9	negative selection	9905847
86263951	86263974	2	+	27869803	PATU8988S	viability after 31 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	0.20315688069894	[1083]	[490,505,NaN]	2	hSpCas9	negative selection	9905848
86338040	86338063	2	-	27869803	PATU8988S	viability after 31 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.0047222585968715175	[508]	[134,290,NaN]	0	hSpCas9	negative selection	9905849
86217039	86217062	2	+	27869803	HPAFII	viability after 35 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.8764643296430568	[359]	[446,207,NaN]	6	hSpCas9	negative selection	9988293
86232665	86232688	2	+	27869803	HPAFII	viability after 35 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.7365978134198838	[171]	[165,429,NaN]	9	hSpCas9	negative selection	9988294
86251977	86252000	2	-	27869803	HPAFII	viability after 35 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.3053761420188261	[630]	[83,454,NaN]	-2	hSpCas9	negative selection	9988295
86254724	86254747	2	+	27869803	HPAFII	viability after 35 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.21651134168577846	[93]	[51,58,NaN]	1	hSpCas9	negative selection	9988296
86263951	86263974	2	+	27869803	HPAFII	viability after 35 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-1.011343960376732	[621]	[103,214,NaN]	-5	hSpCas9	negative selection	9988297
86338040	86338063	2	-	27869803	HPAFII	viability after 35 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.4093475612867835	[255]	[292,35,NaN]	2	hSpCas9	negative selection	9988298
86217039	86217062	2	+	27869803	HPAFII	viability after 31 days	TCACGTGGTTTCGGTGGCCGAGG	REEP1	ENSG00000068615	0.7006715151665495	[359]	[436,209,NaN]	5	hSpCas9	negative selection	10070742
86232665	86232688	2	+	27869803	HPAFII	viability after 31 days	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.576852529686665	[171]	[74,519,NaN]	9	hSpCas9	negative selection	10070743
86251977	86252000	2	-	27869803	HPAFII	viability after 31 days	CTTGAACGTGGCCGCCACAGCGG	REEP1	ENSG00000068615	-0.8462824288849884	[630]	[39,367,NaN]	-5	hSpCas9	negative selection	10070744
86254724	86254747	2	+	27869803	HPAFII	viability after 31 days	AAACTTCCTGTACAGGAGGCTGG	REEP1	ENSG00000068615	0.6183778848720802	[93]	[102,56,NaN]	4	hSpCas9	negative selection	10070745
86263951	86263974	2	+	27869803	HPAFII	viability after 31 days	CCTGGAGTACTTACCAACAAAGG	REEP1	ENSG00000068615	-0.8022043568789619	[621]	[114,292,NaN]	-5	hSpCas9	negative selection	10070746
86338040	86338063	2	-	27869803	HPAFII	viability after 31 days	GAGCAACGGACAGACTGAAGAGG	REEP1	ENSG00000068615	0.12602150204037438	[255]	[285,15,NaN]	0	hSpCas9	negative selection	10070747
86232738	86232761	2	-	28162770	P31FUJ	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.29419022766944747	[346]	[499]	3	hSpCas9	negative selection	10223839
86251989	86252012	2	-	28162770	P31FUJ	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.162143876924996	[234]	[308]	1	hSpCas9	negative selection	10223840
86232728	86232751	2	+	28162770	P31FUJ	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.02635132694695219	[441]	[509]	0	hSpCas9	negative selection	10223841
86232773	86232796	2	-	28162770	P31FUJ	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.20148138380910946	[241]	[326]	2	hSpCas9	negative selection	10223842
86232635	86232658	2	+	28162770	P31FUJ	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.24680729616054875	[70]	[98]	2	hSpCas9	negative selection	10223843
86232672	86232695	2	-	28162770	P31FUJ	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.9306965278685007	[99]	[223]	9	hSpCas9	negative selection	10223844
86232665	86232688	2	+	28162770	P31FUJ	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-3.2328022044143783	[7]	[0]	-9	hSpCas9	negative selection	10223845
86263979	86264002	2	+	28162770	P31FUJ	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.2551358419119131	[327]	[459]	2	hSpCas9	negative selection	10223846
86232757	86232780	2	-	28162770	P31FUJ	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-3.2328022044143783	[7]	[0]	-9	hSpCas9	negative selection	10223847
86232645	86232668	2	+	28162770	P31FUJ	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.42314101385224023	[270]	[426]	5	hSpCas9	negative selection	10223848
86232738	86232761	2	-	28162770	TF1	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	NaN	[NaN]	[494]	1	hSpCas9	negative selection	10393205
86251989	86252012	2	-	28162770	TF1	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10393206
86232728	86232751	2	+	28162770	TF1	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10393207
86232773	86232796	2	-	28162770	TF1	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10393208
86232635	86232658	2	+	28162770	TF1	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10393209
86232672	86232695	2	-	28162770	TF1	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10393210
86232665	86232688	2	+	28162770	TF1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10393211
86263979	86264002	2	+	28162770	TF1	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10393212
86232757	86232780	2	-	28162770	TF1	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10393213
86232645	86232668	2	+	28162770	TF1	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	NaN	[NaN]	[433]	1	hSpCas9	negative selection	10393214
86232738	86232761	2	-	28162770	SKM1	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.06118463699524468	[134]	[248]	0	hSpCas9	negative selection	10562571
86251989	86252012	2	-	28162770	SKM1	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10562572
86232728	86232751	2	+	28162770	SKM1	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.06864166560513096	[139]	[235]	0	hSpCas9	negative selection	10562573
86232773	86232796	2	-	28162770	SKM1	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.732587153655632	[63]	[187]	7	hSpCas9	negative selection	10562574
86232635	86232658	2	+	28162770	SKM1	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10562575
86232672	86232695	2	-	28162770	SKM1	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.531635256592695	[35]	[91]	5	hSpCas9	negative selection	10562576
86232665	86232688	2	+	28162770	SKM1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10562577
86263979	86264002	2	+	28162770	SKM1	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.10644504095296031	[61]	[117]	1	hSpCas9	negative selection	10562578
86232757	86232780	2	-	28162770	SKM1	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10562579
86232645	86232668	2	+	28162770	SKM1	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.9888422101154783	[58]	[206]	8	hSpCas9	negative selection	10562580
86232738	86232761	2	-	28162770	SKM1	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.06118463699524468	[134]	[248]	0	hSpCas9	negative selection	10731937
86251989	86252012	2	-	28162770	SKM1	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	-0.12156197988091315	[63]	[103]	-1	hSpCas9	negative selection	10731938
86232728	86232751	2	+	28162770	SKM1	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.06864166560513096	[139]	[235]	0	hSpCas9	negative selection	10731939
86232773	86232796	2	-	28162770	SKM1	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.732587153655632	[63]	[187]	7	hSpCas9	negative selection	10731940
86232635	86232658	2	+	28162770	SKM1	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10731941
86232672	86232695	2	-	28162770	SKM1	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.531635256592695	[35]	[91]	5	hSpCas9	negative selection	10731942
86232665	86232688	2	+	28162770	SKM1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10731943
86263979	86264002	2	+	28162770	SKM1	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.10644504095296031	[61]	[117]	1	hSpCas9	negative selection	10731944
86232757	86232780	2	-	28162770	SKM1	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10731945
86232645	86232668	2	+	28162770	SKM1	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.9888422101154783	[58]	[206]	8	hSpCas9	negative selection	10731946
86232738	86232761	2	-	28162770	PL21	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.7419818988406564	[565]	[411]	6	hSpCas9	negative selection	10901303
86251989	86252012	2	-	28162770	PL21	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	1.148300682969702	[169]	[163]	8	hSpCas9	negative selection	10901304
86232728	86232751	2	+	28162770	PL21	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.6753618433927943	[465]	[126]	-5	hSpCas9	negative selection	10901305
86232773	86232796	2	-	28162770	PL21	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.05104811646417351	[274]	[123]	0	hSpCas9	negative selection	10901306
86232635	86232658	2	+	28162770	PL21	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	-0.7807515625629751	[74]	[18]	-5	hSpCas9	negative selection	10901307
86232672	86232695	2	-	28162770	PL21	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.04193517270882763	[122]	[51]	0	hSpCas9	negative selection	10901308
86232665	86232688	2	+	28162770	PL21	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.38482288623183614	[2]	[0]	-3	hSpCas9	negative selection	10901309
86263979	86264002	2	+	28162770	PL21	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.608693080197965	[222]	[147]	5	hSpCas9	negative selection	10901310
86232757	86232780	2	-	28162770	PL21	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	0.714712787319078	[6]	[4]	6	hSpCas9	negative selection	10901311
86232645	86232668	2	+	28162770	PL21	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.030214613047007732	[233]	[103]	0	hSpCas9	negative selection	10901312
86232738	86232761	2	-	28162770	P31FUJ	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.29419022766944747	[346]	[499]	3	hSpCas9	negative selection	11070669
86251989	86252012	2	-	28162770	P31FUJ	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.162143876924996	[234]	[308]	1	hSpCas9	negative selection	11070670
86232728	86232751	2	+	28162770	P31FUJ	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.02635132694695219	[441]	[509]	0	hSpCas9	negative selection	11070671
86232773	86232796	2	-	28162770	P31FUJ	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.20148138380910946	[241]	[326]	2	hSpCas9	negative selection	11070672
86232635	86232658	2	+	28162770	P31FUJ	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.24680729616054875	[70]	[98]	2	hSpCas9	negative selection	11070673
86232672	86232695	2	-	28162770	P31FUJ	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.9306965278685007	[99]	[223]	9	hSpCas9	negative selection	11070674
86232665	86232688	2	+	28162770	P31FUJ	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-3.2328022044143783	[7]	[0]	-9	hSpCas9	negative selection	11070675
86263979	86264002	2	+	28162770	P31FUJ	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.2551358419119131	[327]	[459]	2	hSpCas9	negative selection	11070676
86232757	86232780	2	-	28162770	P31FUJ	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-3.2328022044143783	[7]	[0]	-9	hSpCas9	negative selection	11070677
86232645	86232668	2	+	28162770	P31FUJ	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.42314101385224023	[270]	[426]	5	hSpCas9	negative selection	11070678
86232738	86232761	2	-	28162770	OCIAML5	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	-0.35071350279359526	[295]	[418]	-2	hSpCas9	negative selection	11240035
86251989	86252012	2	-	28162770	OCIAML5	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.8050457156129944	[155]	[491]	7	hSpCas9	negative selection	11240036
86232728	86232751	2	+	28162770	OCIAML5	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	0.23294145434249103	[172]	[366]	2	hSpCas9	negative selection	11240037
86232773	86232796	2	-	28162770	OCIAML5	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.9403380097276355	[96]	[335]	7	hSpCas9	negative selection	11240038
86232635	86232658	2	+	28162770	OCIAML5	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	1.0654712689440298	[35]	[135]	8	hSpCas9	negative selection	11240039
86232672	86232695	2	-	28162770	OCIAML5	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	1.1564954426394272	[41]	[168]	8	hSpCas9	negative selection	11240040
86232665	86232688	2	+	28162770	OCIAML5	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11240041
86263979	86264002	2	+	28162770	OCIAML5	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.4889703469710701	[194]	[493]	4	hSpCas9	negative selection	11240042
86232757	86232780	2	-	28162770	OCIAML5	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	3.9552883511936074	[0]	[27]	9	hSpCas9	negative selection	11240043
86232645	86232668	2	+	28162770	OCIAML5	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.8490219869736126	[170]	[555]	7	hSpCas9	negative selection	11240044
86232738	86232761	2	-	28162770	EOL1	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.45603139028080864	[915]	[661]	4	hSpCas9	negative selection	11409401
86251989	86252012	2	-	28162770	EOL1	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.9122694417920978	[235]	[233]	7	hSpCas9	negative selection	11409402
86232728	86232751	2	+	28162770	EOL1	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.39511845448525684	[955]	[382]	-3	hSpCas9	negative selection	11409403
86232773	86232796	2	-	28162770	EOL1	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.8950218192673626	[542]	[531]	7	hSpCas9	negative selection	11409404
86232635	86232658	2	+	28162770	EOL1	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	-1.0103572002075805	[129]	[33]	-6	hSpCas9	negative selection	11409405
86232672	86232695	2	-	28162770	EOL1	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.2736973351929213	[167]	[106]	2	hSpCas9	negative selection	11409406
86232665	86232688	2	+	28162770	EOL1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-0.07545222842946586	[1]	[0]	0	hSpCas9	negative selection	11409407
86263979	86264002	2	+	28162770	EOL1	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.07851907137936429	[292]	[162]	0	hSpCas9	negative selection	11409408
86232757	86232780	2	-	28162770	EOL1	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-1.0754522284294659	[3]	[0]	-6	hSpCas9	negative selection	11409409
86232645	86232668	2	+	28162770	EOL1	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.23387582967826337	[275]	[170]	2	hSpCas9	negative selection	11409410
86232738	86232761	2	-	28162770	MOLM13	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.8211094927467035	[601]	[768]	6	hSpCas9	negative selection	11578767
86251989	86252012	2	-	28162770	MOLM13	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.9685355963322595	[228]	[323]	7	hSpCas9	negative selection	11578768
86232728	86232751	2	+	28162770	MOLM13	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.21492044257472198	[670]	[417]	-1	hSpCas9	negative selection	11578769
86232773	86232796	2	-	28162770	MOLM13	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.9409186035825983	[383]	[532]	7	hSpCas9	negative selection	11578770
86232635	86232658	2	+	28162770	MOLM13	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.294557778659017	[105]	[93]	2	hSpCas9	negative selection	11578771
86232672	86232695	2	-	28162770	MOLM13	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.19035540601566991	[159]	[131]	1	hSpCas9	negative selection	11578772
86232665	86232688	2	+	28162770	MOLM13	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11578773
86263979	86264002	2	+	28162770	MOLM13	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.16363231298427205	[425]	[344]	1	hSpCas9	negative selection	11578774
86232757	86232780	2	-	28162770	MOLM13	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-3.232550336596514	[12]	[0]	-8	hSpCas9	negative selection	11578775
86232645	86232668	2	+	28162770	MOLM13	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	1.0528518822657351	[375]	[563]	7	hSpCas9	negative selection	11578776
86232738	86232761	2	-	28162770	HEL	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.06840788300908773	[675]	[453]	0	hSpCas9	negative selection	11748133
86251989	86252012	2	-	28162770	HEL	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.22770133272151313	[195]	[146]	1	hSpCas9	negative selection	11748134
86232728	86232751	2	+	28162770	HEL	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.9343184706354533	[727]	[243]	-5	hSpCas9	negative selection	11748135
86232773	86232796	2	-	28162770	HEL	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.10394651271212685	[368]	[253]	0	hSpCas9	negative selection	11748136
86232635	86232658	2	+	28162770	HEL	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	1.3036501859548117	[73]	[116]	9	hSpCas9	negative selection	11748137
86232672	86232695	2	-	28162770	HEL	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.43992194900066983	[121]	[105]	3	hSpCas9	negative selection	11748138
86232665	86232688	2	+	28162770	HEL	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	1.057776331279201	[5]	[7]	8	hSpCas9	negative selection	11748139
86263979	86264002	2	+	28162770	HEL	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.3270158866397026	[289]	[232]	2	hSpCas9	negative selection	11748140
86232757	86232780	2	-	28162770	HEL	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	5.16630078805737	[0]	[22]	9	hSpCas9	negative selection	11748141
86232645	86232668	2	+	28162770	HEL	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	-0.1868208262979167	[310]	[174]	-1	hSpCas9	negative selection	11748142
86232738	86232761	2	-	28162770	MV411	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.6313812809600505	[468]	[611]	6	hSpCas9	negative selection	11917499
86251989	86252012	2	-	28162770	MV411	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.39039550462481837	[143]	[158]	3	hSpCas9	negative selection	11917500
86232728	86232751	2	+	28162770	MV411	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.8368525939248841	[510]	[240]	-5	hSpCas9	negative selection	11917501
86232773	86232796	2	-	28162770	MV411	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.08697287858952929	[303]	[271]	0	hSpCas9	negative selection	11917502
86232635	86232658	2	+	28162770	MV411	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	-0.26881219985436655	[122]	[85]	-2	hSpCas9	negative selection	11917503
86232672	86232695	2	-	28162770	MV411	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.8730420360012773	[69]	[107]	7	hSpCas9	negative selection	11917504
86232665	86232688	2	+	28162770	MV411	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	0.24743755078277552	[4]	[4]	2	hSpCas9	negative selection	11917505
86263979	86264002	2	+	28162770	MV411	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	-0.4895280433834307	[204]	[122]	-4	hSpCas9	negative selection	11917506
86232757	86232780	2	-	28162770	MV411	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-2.9224874506595375	[8]	[0]	-9	hSpCas9	negative selection	11917507
86232645	86232668	2	+	28162770	MV411	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.9720345875185632	[163]	[270]	8	hSpCas9	negative selection	11917508
86232738	86232761	2	-	28162770	MONOMAC1	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	-0.40984321956680336	[349]	[301]	-4	hSpCas9	negative selection	12086865
86251989	86252012	2	-	28162770	MONOMAC1	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.07426517475784067	[86]	[104]	0	hSpCas9	negative selection	12086866
86232728	86232751	2	+	28162770	MONOMAC1	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	1.026635126503467	[321]	[751]	8	hSpCas9	negative selection	12086867
86232773	86232796	2	-	28162770	MONOMAC1	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.8751129386962816	[155]	[327]	7	hSpCas9	negative selection	12086868
86232635	86232658	2	+	28162770	MONOMAC1	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.5927454455501007	[58]	[101]	6	hSpCas9	negative selection	12086869
86232672	86232695	2	-	28162770	MONOMAC1	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.13893389249598542	[72]	[75]	-1	hSpCas9	negative selection	12086870
86232665	86232688	2	+	28162770	MONOMAC1	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	12086871
86263979	86264002	2	+	28162770	MONOMAC1	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.5134565357454614	[87]	[143]	5	hSpCas9	negative selection	12086872
86232757	86232780	2	-	28162770	MONOMAC1	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12086873
86232645	86232668	2	+	28162770	MONOMAC1	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.5730956110418517	[128]	[219]	5	hSpCas9	negative selection	12086874
86232738	86232761	2	-	28162770	OCIAML2	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	-0.07208044875188624	[109]	[579]	0	hSpCas9	negative selection	12256231
86251989	86252012	2	-	28162770	OCIAML2	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	1.298044628651383	[26]	[367]	9	hSpCas9	negative selection	12256232
86232728	86232751	2	+	28162770	OCIAML2	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	-0.05277731035626343	[95]	[512]	0	hSpCas9	negative selection	12256233
86232773	86232796	2	-	28162770	OCIAML2	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.7224250510387062	[54]	[502]	7	hSpCas9	negative selection	12256234
86232635	86232658	2	+	28162770	OCIAML2	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	1.5084105561221925	[12]	[204]	9	hSpCas9	negative selection	12256235
86232672	86232695	2	-	28162770	OCIAML2	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	-0.03322451293486295	[23]	[129]	0	hSpCas9	negative selection	12256236
86232665	86232688	2	+	28162770	OCIAML2	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	-1.8856673245210054	[1]	[2]	-8	hSpCas9	negative selection	12256237
86263979	86264002	2	+	28162770	OCIAML2	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.6813732682028888	[35]	[319]	6	hSpCas9	negative selection	12256238
86232757	86232780	2	-	28162770	OCIAML2	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	-1.4706298252421615	[0]	[1]	-7	hSpCas9	negative selection	12256239
86232645	86232668	2	+	28162770	OCIAML2	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.42320461754091093	[36]	[274]	4	hSpCas9	negative selection	12256240
86232738	86232761	2	-	28162770	OCIAML3	viability	CAGGACCTCACCACCATCAGGGG	REEP1	ENSG00000068615	0.07080816808620738	[122]	[389]	0	hSpCas9	negative selection	12425597
86251989	86252012	2	-	28162770	OCIAML3	viability	CGGGAAGCGGGGCTTGAACGTGG	REEP1	ENSG00000068615	0.02412172433219223	[42]	[131]	0	hSpCas9	negative selection	12425598
86232728	86232751	2	+	28162770	OCIAML3	viability	GGCGCCGTCTCCCCTGATGGTGG	REEP1	ENSG00000068615	0.20262087514038218	[134]	[468]	2	hSpCas9	negative selection	12425599
86232773	86232796	2	-	28162770	OCIAML3	viability	GTGCCTTATCGGAGAGACTGCGG	REEP1	ENSG00000068615	0.055974652247403056	[93]	[294]	0	hSpCas9	negative selection	12425600
86232635	86232658	2	+	28162770	OCIAML3	viability	AGCGCTCTCAGAAGCACTCCTGG	REEP1	ENSG00000068615	0.30215654869129693	[17]	[66]	3	hSpCas9	negative selection	12425601
86232672	86232695	2	-	28162770	OCIAML3	viability	GGGCGGGCCAGCGGCAAACACGG	REEP1	ENSG00000068615	0.17858186357276418	[23]	[81]	1	hSpCas9	negative selection	12425602
86232665	86232688	2	+	28162770	OCIAML3	viability	AGGCTGGCCGTGTTTGCCGCTGG	REEP1	ENSG00000068615	2.1064320778169296	[0]	[12]	9	hSpCas9	negative selection	12425603
86263979	86264002	2	+	28162770	OCIAML3	viability	GTCTGTGAATGTCTCTGCTGTGG	REEP1	ENSG00000068615	0.21334728173344109	[75]	[265]	2	hSpCas9	negative selection	12425604
86232757	86232780	2	-	28162770	OCIAML3	viability	ACTGCGGAGCTTCAGCATGCAGG	REEP1	ENSG00000068615	2.3128829552843557	[0]	[14]	9	hSpCas9	negative selection	12425605
86232645	86232668	2	+	28162770	OCIAML3	viability	GAAGCACTCCTGGACATCTTAGG	REEP1	ENSG00000068615	0.19448825448212514	[65]	[227]	1	hSpCas9	negative selection	12425606