Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23221
• Symbol: RHOBTB2
• Description: Rho related BTB domain containing 2

DataSource: http://genomecrispr.dkfz.de/#!/results/RHOBTB2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23006905	23006928	8	-	26472758	Jiyoye	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	1.1722194987055135	[172]	[293]	7	hSpCas9	negative selection	136794
23006092	23006115	8	+	26472758	Jiyoye	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	2.799492804284633	[3]	[20]	9	hSpCas9	negative selection	136795
23004505	23004528	8	-	26472758	Jiyoye	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	1.3674656717039022	[220]	[429]	7	hSpCas9	negative selection	136796
23004532	23004555	8	-	26472758	Jiyoye	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.9217485543356315	[55]	[79]	6	hSpCas9	negative selection	136797
23005422	23005445	8	-	26472758	Jiyoye	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.31554490604030494	[64]	[60]	2	hSpCas9	negative selection	136798
23007016	23007039	8	-	26472758	Jiyoye	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	-0.1777871192152829	[254]	[169]	-1	hSpCas9	negative selection	136799
23007102	23007125	8	-	26472758	Jiyoye	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-0.5103624583021533	[16]	[8]	-4	hSpCas9	negative selection	136800
23008037	23008060	8	-	26472758	Jiyoye	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	1.6398361382961486	[19]	[46]	8	hSpCas9	negative selection	136801
23004473	23004496	8	+	26472758	Jiyoye	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	-0.5967396684975099	[368]	[183]	-4	hSpCas9	negative selection	136802
23005455	23005478	8	-	26472758	Jiyoye	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.3428463654857792	[36]	[21]	-2	hSpCas9	negative selection	136803
23006905	23006928	8	-	26472758	KBM7	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.3357511156331451	[1228,677]	[516,193]	-3	hSpCas9	negative selection	327912
23006092	23006115	8	+	26472758	KBM7	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.7997829091706228	[72,111]	[101,55]	8	hSpCas9	negative selection	327913
23004505	23004528	8	-	26472758	KBM7	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.1642337789791568	[1265,1017]	[617,579]	1	hSpCas9	negative selection	327914
23004532	23004555	8	-	26472758	KBM7	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.7396279902828407	[380,142]	[118,266]	7	hSpCas9	negative selection	327915
23005422	23005445	8	-	26472758	KBM7	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	-0.005119762922615956	[325,186]	[80,149]	0	hSpCas9	negative selection	327916
23007016	23007039	8	-	26472758	KBM7	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.673708797031412	[559,399]	[390,323]	7	hSpCas9	negative selection	327917
23007102	23007125	8	-	26472758	KBM7	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.4590963658073195	[125,94]	[84,57]	5	hSpCas9	negative selection	327918
23008037	23008060	8	-	26472758	KBM7	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	-0.6890355239604429	[214,235]	[39,89]	-5	hSpCas9	negative selection	327919
23004473	23004496	8	+	26472758	KBM7	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.6487336291514407	[1107,1055]	[1138,495]	7	hSpCas9	negative selection	327920
23005455	23005478	8	-	26472758	KBM7	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.049776009218919226	[169,245]	[139,57]	0	hSpCas9	negative selection	327921
23006905	23006928	8	-	26472758	Raji	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.18952182194407774	[494]	[130]	1	hSpCas9	negative selection	519030
23006092	23006115	8	+	26472758	Raji	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.42931163026096186	[63]	[19]	4	hSpCas9	negative selection	519031
23004505	23004528	8	-	26472758	Raji	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.6502958572046011	[614]	[223]	6	hSpCas9	negative selection	519032
23004532	23004555	8	-	26472758	Raji	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.6197182360073581	[128]	[45]	6	hSpCas9	negative selection	519033
23005422	23005445	8	-	26472758	Raji	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	1.1073835353735995	[95]	[47]	8	hSpCas9	negative selection	519034
23007016	23007039	8	-	26472758	Raji	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.1431842568014463	[198]	[101]	8	hSpCas9	negative selection	519035
23007102	23007125	8	-	26472758	Raji	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-0.18539821385424649	[48]	[9]	-1	hSpCas9	negative selection	519036
23008037	23008060	8	-	26472758	Raji	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	1.2517734447087743	[75]	[41]	9	hSpCas9	negative selection	519037
23004473	23004496	8	+	26472758	Raji	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.062337055596664914	[552]	[133]	0	hSpCas9	negative selection	519038
23005455	23005478	8	-	26472758	Raji	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.3317280988841018	[140]	[25]	-3	hSpCas9	negative selection	519039
23006905	23006928	8	-	26472758	K562	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.057060357773434545	[894]	[785]	0	hSpCas9	negative selection	710148
23006092	23006115	8	+	26472758	K562	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.4392349046504702	[82]	[94]	3	hSpCas9	negative selection	710149
23004505	23004528	8	-	26472758	K562	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.14287378112949267	[823]	[629]	-1	hSpCas9	negative selection	710150
23004532	23004555	8	-	26472758	K562	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.6626027822621547	[228]	[305]	5	hSpCas9	negative selection	710151
23005422	23005445	8	-	26472758	K562	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	1.2922953546172278	[162]	[336]	9	hSpCas9	negative selection	710152
23007016	23007039	8	-	26472758	K562	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.5007584809262324	[395]	[945]	9	hSpCas9	negative selection	710153
23007102	23007125	8	-	26472758	K562	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-1.8613759363561497	[98]	[22]	-7	hSpCas9	negative selection	710154
23008037	23008060	8	-	26472758	K562	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.2841649064592032	[178]	[183]	2	hSpCas9	negative selection	710155
23004473	23004496	8	+	26472758	K562	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.9773457276570428	[786]	[1307]	7	hSpCas9	negative selection	710156
23005455	23005478	8	-	26472758	K562	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.6329619856695974	[247]	[134]	-4	hSpCas9	negative selection	710157
22994624	22994647	8	-	26627737	DLD1	viability	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.7081401950792661	[688]	[413,468,200]	7	hSpCas9	negative selection	839074
23004605	23004628	8	+	26627737	DLD1	viability	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.25692051999744936	[746]	[197,387,258]	2	hSpCas9	negative selection	839075
23005455	23005478	8	-	26627737	DLD1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.32764374936421337	[402]	[113,88,97]	-3	hSpCas9	negative selection	839076
23006135	23006158	8	-	26627737	DLD1	viability	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.20333313484800952	[237]	[104,39,49]	-2	hSpCas9	negative selection	839077
23006902	23006925	8	-	26627737	DLD1	viability	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.716312854608116	[286]	[159,246,53]	7	hSpCas9	negative selection	839078
23008101	23008124	8	-	26627737	DLD1	viability	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.1994813201170023	[350]	[197,206,335]	9	hSpCas9	negative selection	839079
22994624	22994647	8	-	26627737	GBM cells	viability after 5 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.16243991304350425	[488]	[299,286]	2	hSpCas9	negative selection	921389
23004605	23004628	8	+	26627737	GBM cells	viability after 5 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.6179259049160175	[454]	[155,161]	-7	hSpCas9	negative selection	921390
23005455	23005478	8	-	26627737	GBM cells	viability after 5 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.06219967896496266	[241]	[138,131]	1	hSpCas9	negative selection	921391
23006135	23006158	8	-	26627737	GBM cells	viability after 5 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	0.23594886216325617	[94]	[47,71]	3	hSpCas9	negative selection	921392
23006902	23006925	8	-	26627737	GBM cells	viability after 5 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.6874097696919739	[153]	[122,142]	8	hSpCas9	negative selection	921393
23008101	23008124	8	-	26627737	GBM cells	viability after 5 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.22474459286540277	[279]	[113,142]	-3	hSpCas9	negative selection	921394
22994624	22994647	8	-	26627737	GBM cells	viability after 13 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.08570502137634273	[488]	[296,268]	1	hSpCas9	negative selection	1003704
23004605	23004628	8	+	26627737	GBM cells	viability after 13 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.19165206400498214	[454]	[192,234]	-2	hSpCas9	negative selection	1003705
23005455	23005478	8	-	26627737	GBM cells	viability after 13 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.025047844174991674	[241]	[169,103]	0	hSpCas9	negative selection	1003706
23006135	23006158	8	-	26627737	GBM cells	viability after 13 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.5946845186583574	[94]	[21,43]	-6	hSpCas9	negative selection	1003707
23006902	23006925	8	-	26627737	GBM cells	viability after 13 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.8810695016006093	[153]	[138,165]	8	hSpCas9	negative selection	1003708
23008101	23008124	8	-	26627737	GBM cells	viability after 13 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.4286916994719544	[279]	[124,102]	-5	hSpCas9	negative selection	1003709
22994624	22994647	8	-	26627737	GBM cells	viability after 21 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.31276770445680546	[488]	[353,307]	3	hSpCas9	negative selection	1086019
23004605	23004628	8	+	26627737	GBM cells	viability after 21 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.2756376486344676	[454]	[328,271]	3	hSpCas9	negative selection	1086020
23005455	23005478	8	-	26627737	GBM cells	viability after 21 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.10841826781579857	[241]	[122,120]	-1	hSpCas9	negative selection	1086021
23006135	23006158	8	-	26627737	GBM cells	viability after 21 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.49409972160749693	[94]	[44,28]	-4	hSpCas9	negative selection	1086022
23006902	23006925	8	-	26627737	GBM cells	viability after 21 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.2222560015962811	[153]	[213,177]	9	hSpCas9	negative selection	1086023
23008101	23008124	8	-	26627737	GBM cells	viability after 21 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.7286274688028627	[279]	[72,108]	-6	hSpCas9	negative selection	1086024
22994624	22994647	8	-	26627737	RPE1	viability after 9 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-0.9260409714311492	[2507]	[531,259]	-6	hSpCas9	negative selection	1168334
23004605	23004628	8	+	26627737	RPE1	viability after 9 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	1.6512541923037722	[785]	[954,537]	8	hSpCas9	negative selection	1168335
23005455	23005478	8	-	26627737	RPE1	viability after 9 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.2349265268802132	[738]	[120,68]	-7	hSpCas9	negative selection	1168336
23006135	23006158	8	-	26627737	RPE1	viability after 9 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.4095895735409798	[296]	[7,149]	-3	hSpCas9	negative selection	1168337
23006902	23006925	8	-	26627737	RPE1	viability after 9 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.4211405330834912	[349]	[261,333]	7	hSpCas9	negative selection	1168338
23008101	23008124	8	-	26627737	RPE1	viability after 9 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.43073391933997	[349]	[335,242]	7	hSpCas9	negative selection	1168339
22994624	22994647	8	-	26627737	RPE1	viability after 12 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-1.0883914091654683	[2507]	[363,266]	-6	hSpCas9	negative selection	1250649
23004605	23004628	8	+	26627737	RPE1	viability after 12 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	1.5357197991822114	[785]	[790,422]	8	hSpCas9	negative selection	1250650
23005455	23005478	8	-	26627737	RPE1	viability after 12 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.048786079183481	[738]	[145,42]	-6	hSpCas9	negative selection	1250651
23006135	23006158	8	-	26627737	RPE1	viability after 12 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	0.16537777121844632	[296]	[71,107]	1	hSpCas9	negative selection	1250652
23006902	23006925	8	-	26627737	RPE1	viability after 12 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.9902509446631088	[349]	[145,229]	6	hSpCas9	negative selection	1250653
23008101	23008124	8	-	26627737	RPE1	viability after 12 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.6179706093270454	[349]	[343,229]	8	hSpCas9	negative selection	1250654
22994624	22994647	8	-	26627737	RPE1	viability after 15 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-1.2575180365878187	[2507]	[451,146]	-7	hSpCas9	negative selection	1332964
23004605	23004628	8	+	26627737	RPE1	viability after 15 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	1.648181520186729	[785]	[1095,311]	8	hSpCas9	negative selection	1332965
23005455	23005478	8	-	26627737	RPE1	viability after 15 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.6372874952244729	[738]	[139,128]	-4	hSpCas9	negative selection	1332966
23006135	23006158	8	-	26627737	RPE1	viability after 15 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-2.3238527526434574	[296]	[0,31]	-8	hSpCas9	negative selection	1332967
23006902	23006925	8	-	26627737	RPE1	viability after 15 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.3814360481213217	[349]	[204,308]	7	hSpCas9	negative selection	1332968
23008101	23008124	8	-	26627737	RPE1	viability after 15 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.7162992217048114	[349]	[362,288]	8	hSpCas9	negative selection	1332969
22994624	22994647	8	-	26627737	RPE1	viability after 18 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-0.6725414495761528	[2507]	[559,279]	-4	hSpCas9	negative selection	1415279
23004605	23004628	8	+	26627737	RPE1	viability after 18 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	1.5735047717297934	[785]	[829,418]	8	hSpCas9	negative selection	1415280
23005455	23005478	8	-	26627737	RPE1	viability after 18 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.614032288736472	[738]	[54,75]	-7	hSpCas9	negative selection	1415281
23006135	23006158	8	-	26627737	RPE1	viability after 18 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.1144585041260444	[296]	[22,51]	-6	hSpCas9	negative selection	1415282
23006902	23006925	8	-	26627737	RPE1	viability after 18 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.1948948979906953	[349]	[222,208]	6	hSpCas9	negative selection	1415283
23008101	23008124	8	-	26627737	RPE1	viability after 18 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.4471114538381467	[349]	[316,193]	7	hSpCas9	negative selection	1415284
22994624	22994647	8	-	26627737	HeLa	viability after 8 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.6320236159588872	[595]	[419,569,231]	5	hSpCas9	negative selection	1497594
23004605	23004628	8	+	26627737	HeLa	viability after 8 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.5353626502198497	[392]	[244,295,204]	5	hSpCas9	negative selection	1497595
23005455	23005478	8	-	26627737	HeLa	viability after 8 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.4900708626803591	[286]	[140,59,77]	-5	hSpCas9	negative selection	1497596
23006135	23006158	8	-	26627737	HeLa	viability after 8 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.6669644415620034	[222]	[115,11,66]	-6	hSpCas9	negative selection	1497597
23006902	23006925	8	-	26627737	HeLa	viability after 8 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.145981969925616	[141]	[429,44,8]	8	hSpCas9	negative selection	1497598
23008101	23008124	8	-	26627737	HeLa	viability after 8 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-1.044945090671581	[455]	[160,48,92]	-8	hSpCas9	negative selection	1497599
22994624	22994647	8	-	26627737	HeLa	viability after 12 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.47634357685495776	[595]	[403,349,274]	4	hSpCas9	negative selection	1579909
23004605	23004628	8	+	26627737	HeLa	viability after 12 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.6573713439275908	[392]	[75,248,438]	5	hSpCas9	negative selection	1579910
23005455	23005478	8	-	26627737	HeLa	viability after 12 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.09871947033123674	[286]	[166,90,127]	0	hSpCas9	negative selection	1579911
23006135	23006158	8	-	26627737	HeLa	viability after 12 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.4510697279008916	[222]	[14,26,162]	-4	hSpCas9	negative selection	1579912
23006902	23006925	8	-	26627737	HeLa	viability after 12 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.894682121423351	[141]	[275,239,137]	9	hSpCas9	negative selection	1579913
23008101	23008124	8	-	26627737	HeLa	viability after 12 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.5274225708286064	[455]	[93,103,195]	-5	hSpCas9	negative selection	1579914
22994624	22994647	8	-	26627737	HeLa	viability after 15 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-0.38102119166920234	[595]	[191,166,200]	-3	hSpCas9	negative selection	1662224
23004605	23004628	8	+	26627737	HeLa	viability after 15 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.8490252887520301	[392]	[292,216,359]	6	hSpCas9	negative selection	1662225
23005455	23005478	8	-	26627737	HeLa	viability after 15 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.1877013509322581	[286]	[116,118,68]	-1	hSpCas9	negative selection	1662226
23006135	23006158	8	-	26627737	HeLa	viability after 15 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.2971702831286561	[222]	[33,67,123]	-3	hSpCas9	negative selection	1662227
23006902	23006925	8	-	26627737	HeLa	viability after 15 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.669052316145944	[141]	[67,276,209]	9	hSpCas9	negative selection	1662228
23008101	23008124	8	-	26627737	HeLa	viability after 15 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-1.5163259699132152	[455]	[82,51,58]	-8	hSpCas9	negative selection	1662229
22994624	22994647	8	-	26627737	HeLa	viability after 18 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-0.348158813724171	[595]	[130,145,200]	-3	hSpCas9	negative selection	1744539
23004605	23004628	8	+	26627737	HeLa	viability after 18 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.8466072388953343	[392]	[192,182,359]	6	hSpCas9	negative selection	1744540
23005455	23005478	8	-	26627737	HeLa	viability after 18 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.2312345165086362	[286]	[76,92,68]	-2	hSpCas9	negative selection	1744541
23006135	23006158	8	-	26627737	HeLa	viability after 18 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.25812654053789974	[222]	[22,60,123]	-2	hSpCas9	negative selection	1744542
23006902	23006925	8	-	26627737	HeLa	viability after 18 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.712308137130147	[141]	[43,244,209]	9	hSpCas9	negative selection	1744543
23008101	23008124	8	-	26627737	HeLa	viability after 18 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-1.4706122713785723	[455]	[58,43,58]	-8	hSpCas9	negative selection	1744544
22994624	22994647	8	-	26627737	HCT116	viability after 6 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	-0.47962294746378337	[629]	[168,16]	-3	hSpCas9	negative selection	1826854
23004605	23004628	8	+	26627737	HCT116	viability after 6 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.5028980217920146	[828]	[388,71]	3	hSpCas9	negative selection	1826855
23005455	23005478	8	-	26627737	HCT116	viability after 6 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.24953839565887567	[653]	[225,64]	1	hSpCas9	negative selection	1826856
23006135	23006158	8	-	26627737	HCT116	viability after 6 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	0.9551827937194504	[252]	[60,85]	5	hSpCas9	negative selection	1826857
23006902	23006925	8	-	26627737	HCT116	viability after 6 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	2.828038811764377	[103]	[322,1]	9	hSpCas9	negative selection	1826858
23008101	23008124	8	-	26627737	HCT116	viability after 6 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	1.447430807415875	[594]	[597,65]	7	hSpCas9	negative selection	1826859
22994624	22994647	8	-	26627737	HCT116	viability after 8 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.4737545777140537	[395]	[373,286,249]	5	hSpCas9	negative selection	1909169
23004605	23004628	8	+	26627737	HCT116	viability after 8 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.10083549404541481	[483]	[307,395,155]	1	hSpCas9	negative selection	1909170
23005455	23005478	8	-	26627737	HCT116	viability after 8 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.3491158174657767	[280]	[322,78,191]	4	hSpCas9	negative selection	1909171
23006135	23006158	8	-	26627737	HCT116	viability after 8 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.4714810021509726	[144]	[22,6,55]	-9	hSpCas9	negative selection	1909172
23006902	23006925	8	-	26627737	HCT116	viability after 8 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	1.815142744410507	[56]	[88,115,125]	9	hSpCas9	negative selection	1909173
23008101	23008124	8	-	26627737	HCT116	viability after 8 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.05588780038383118	[207]	[203,40,113]	0	hSpCas9	negative selection	1909174
22994624	22994647	8	-	26627737	HCT116	viability after 9 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.3266961747761917	[629]	[277,157]	2	hSpCas9	negative selection	1991484
23004605	23004628	8	+	26627737	HCT116	viability after 9 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.09008964258276586	[828]	[181,277]	0	hSpCas9	negative selection	1991485
23005455	23005478	8	-	26627737	HCT116	viability after 9 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.5640827741940704	[653]	[178,69]	-4	hSpCas9	negative selection	1991486
23006135	23006158	8	-	26627737	HCT116	viability after 9 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.09085500244662104	[252]	[44,77]	0	hSpCas9	negative selection	1991487
23006902	23006925	8	-	26627737	HCT116	viability after 9 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.07146697965745741	[103]	[36,22]	0	hSpCas9	negative selection	1991488
23008101	23008124	8	-	26627737	HCT116	viability after 9 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.051398035962005074	[594]	[73,215]	0	hSpCas9	negative selection	1991489
22994624	22994647	8	-	26627737	HCT116	viability after 12 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.45011885778573146	[395]	[262,333,258]	4	hSpCas9	negative selection	2073799
23004605	23004628	8	+	26627737	HCT116	viability after 12 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.040853746054596796	[483]	[260,306,173]	0	hSpCas9	negative selection	2073800
23005455	23005478	8	-	26627737	HCT116	viability after 12 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.0840335481658484	[280]	[173,112,179]	0	hSpCas9	negative selection	2073801
23006135	23006158	8	-	26627737	HCT116	viability after 12 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.872624218640274	[144]	[16,40,68]	-7	hSpCas9	negative selection	2073802
23006902	23006925	8	-	26627737	HCT116	viability after 12 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	2.4512109095058054	[56]	[210,109,164]	9	hSpCas9	negative selection	2073803
23008101	23008124	8	-	26627737	HCT116	viability after 12 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.9517364363341569	[207]	[211,201,219]	7	hSpCas9	negative selection	2073804
22994624	22994647	8	-	26627737	HCT116	viability after 15 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.5449499357088899	[395]	[311,266,412]	5	hSpCas9	negative selection	2156114
23004605	23004628	8	+	26627737	HCT116	viability after 15 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.08989144962769102	[483]	[300,362,125]	-1	hSpCas9	negative selection	2156115
23005455	23005478	8	-	26627737	HCT116	viability after 15 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.02067572430950103	[280]	[257,131,99]	0	hSpCas9	negative selection	2156116
23006135	23006158	8	-	26627737	HCT116	viability after 15 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.2510000163288395	[144]	[37,4,61]	-8	hSpCas9	negative selection	2156117
23006902	23006925	8	-	26627737	HCT116	viability after 15 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	2.7201726433936204	[56]	[330,101,227]	9	hSpCas9	negative selection	2156118
23008101	23008124	8	-	26627737	HCT116	viability after 15 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.3528512401354349	[207]	[234,105,126]	3	hSpCas9	negative selection	2156119
22994624	22994647	8	-	26627737	HCT116	viability after 18 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.7378445566331668	[395]	[370,227,366]	6	hSpCas9	negative selection	2238429
23004605	23004628	8	+	26627737	HCT116	viability after 18 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.3107677200330793	[483]	[398,302,161]	2	hSpCas9	negative selection	2238430
23005455	23005478	8	-	26627737	HCT116	viability after 18 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.2635250128794394	[280]	[101,104,133]	-2	hSpCas9	negative selection	2238431
23006135	23006158	8	-	26627737	HCT116	viability after 18 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.4952932746038323	[144]	[11,0,64]	-8	hSpCas9	negative selection	2238432
23006902	23006925	8	-	26627737	HCT116	viability after 18 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	2.1416352402471848	[56]	[159,26,186]	9	hSpCas9	negative selection	2238433
23008101	23008124	8	-	26627737	HCT116	viability after 18 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-0.07251971636959165	[207]	[130,62,94]	0	hSpCas9	negative selection	2238434
22995708	22995731	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGCCATGAGCAAAAGCAGAGG	RHOBTB2	ENSG00000008853	0.8064479035297198	[20,15]	[6,5]	3	dCas9-VP64	positive selection	2403606
22995681	22995704	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAAGATGCAGAGCCCCAGCAGG	RHOBTB2	ENSG00000008853	1.796359113477783	[15,9]	[13,4]	6	dCas9-VP64	positive selection	2403607
22995745	22995768	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGTGTTCCTACCCTGCAGCTGG	RHOBTB2	ENSG00000008853	3.091585957445435	[46,216]	[88,424]	8	dCas9-VP64	positive selection	2403608
22999480	22999503	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGGGCGGGCGGGGGAAGAAGG	RHOBTB2	ENSG00000008853	0.7139248985947828	[12,28]	[6,6]	3	dCas9-VP64	positive selection	2445368
22999393	22999416	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCCTCCCGCAGCGACGCCGCGG	RHOBTB2	ENSG00000008853	-1.5059552667049894	[93,48]	[2,7]	-8	dCas9-VP64	positive selection	2445369
22999447	22999470	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGCGAGGCGGGATCTGCGGGG	RHOBTB2	ENSG00000008853	-1.8176397138149736	[250,384]	[17,20]	-8	dCas9-VP64	positive selection	2445370
22995708	22995731	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGCCATGAGCAAAAGCAGAGG	RHOBTB2	ENSG00000008853	-0.18532114174256875	[25,104]	[9,25]	-2	dCas9-VP64	positive selection	2498861
22995681	22995704	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAAGATGCAGAGCCCCAGCAGG	RHOBTB2	ENSG00000008853	-1.973572101170472	[5,84]	[1,3]	-9	dCas9-VP64	positive selection	2498862
22995745	22995768	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGTGTTCCTACCCTGCAGCTGG	RHOBTB2	ENSG00000008853	-0.10615572256494657	[64,143]	[24,36]	-1	dCas9-VP64	positive selection	2498863
22999480	22999503	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGGGCGGGCGGGGGAAGAAGG	RHOBTB2	ENSG00000008853	0.2938815156688852	[40,11]	[16,3]	2	dCas9-VP64	positive selection	2540623
22999393	22999416	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCCTCCCGCAGCGACGCCGCGG	RHOBTB2	ENSG00000008853	0.03892314518643747	[104,28]	[35,9]	0	dCas9-VP64	positive selection	2540624
22999447	22999470	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGCGAGGCGGGATCTGCGGGG	RHOBTB2	ENSG00000008853	1.1460673947620894	[23,8]	[10,11]	7	dCas9-VP64	positive selection	2540625
23005455	23005478	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.7915423649816495	[2,2]	[3,4]	9	hSpCas9	positive selection	3016774
23006053	23006076	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	0.8017785966628879	[2,2]	[3,5]	9	hSpCas9	positive selection	3016775
23004606	23004629	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.5298830962581504	[3,3]	[4,4]	9	hSpCas9	positive selection	3016776
23004505	23004528	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.3590833100077854	[3,3]	[3,4]	7	hSpCas9	positive selection	3016777
23005455	23005478	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.4108129692456731	[2,2]	[2,0]	-6	hSpCas9	positive selection	3084632
23006053	23006076	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	-0.3074290387008823	[2,2]	[2,0]	-4	hSpCas9	positive selection	3084633
23004606	23004629	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.30308710701864583	[3,3]	[3,2]	5	hSpCas9	positive selection	3084634
23004505	23004528	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.5893625575661328	[3,3]	[3,4]	8	hSpCas9	positive selection	3084635
23007353	23007376		+	24336571	A375	resistance to PLX after 7 days	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.0370983400399687	[44,52]	[48,50]	1	hSpCas9	positive selection	3140878
23014724	23014747		-	24336571	A375	resistance to PLX after 7 days	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2544296753360795	[56,59]	[69,68]	7	hSpCas9	positive selection	3140879
23007353	23007376		+	24336571	A375	resistance to PLX after 14 days	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	-0.3626117594585896	[43,49]	[18,13]	-4	hSpCas9	positive selection	3198671
23014724	23014747		-	24336571	A375	resistance to PLX after 14 days	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.578768214586963	[60,65]	[52,34]	5	hSpCas9	positive selection	3198672
23007353	23007376		+	24336571	A375	viability after 7 days	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.6192279534400869	[32]	[44,52]	8	hSpCas9	negative selection	3256464
23014724	23014747		-	24336571	A375	viability after 7 days	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.18769829456223253	[53]	[56,59]	3	hSpCas9	negative selection	3256465
23007353	23007376		+	24336571	A375	viability after 14 days	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.586111828994349	[32]	[43,49]	7	hSpCas9	negative selection	3314257
23014724	23014747		-	24336571	A375	viability after 14 days	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.32511093711335803	[53]	[60,65]	4	hSpCas9	negative selection	3314258
23004602	23004625	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.41183616050145977	[344,344]	[2,2]	2	hSpCas9	positive selection	3389792
23014724	23014747	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	-0.7313584753263308	[253,253]	[0,0]	-5	hSpCas9	positive selection	3389793
23004470	23004493	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-1.0418818069414437	[314,314]	[0,0]	-7	hSpCas9	positive selection	3389794
23005455	23005478	8	-	26780180	HT29	viability (Avana library 4 designs)	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	1.18305002055552	[]	[]	4	hSpCas9	negative selection	3455118
23006053	23006076	8	-	26780180	HT29	viability (Avana library 4 designs)	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	0.415894283938694	[]	[]	1	hSpCas9	negative selection	3455119
23004605	23004628	8	+	26780180	HT29	viability (Avana library 4 designs)	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	1.20889412967971	[]	[]	5	hSpCas9	negative selection	3455120
23004505	23004528	8	-	26780180	HT29	viability (Avana library 4 designs)	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.973491071396516	[]	[]	4	hSpCas9	negative selection	3455121
23004505	23004528	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	5.51081212029169	[]	[]	8	hSpCas9	negative selection	3552943
23005455	23005478	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.52285828213227	[]	[]	-2	hSpCas9	negative selection	3552944
23004605	23004628	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	3.84102696713358	[]	[]	6	hSpCas9	negative selection	3552945
23006053	23006076	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	2.88808083236926	[]	[]	4	hSpCas9	negative selection	3552946
23007022	23007045	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAGGACCCGCTCTGCGCGG	RHOBTB2	ENSG00000008853	5.36185165639125	[]	[]	8	hSpCas9	negative selection	3552947
23006797	23006820	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTATGAGACCAGCGTGGTGG	RHOBTB2	ENSG00000008853	0.0114809805209632	[]	[]	0	hSpCas9	negative selection	3552948
23004505	23004528	8	-	26780180	A375	viability (Avana lentiGuide)	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.202002980317374	[]	[]	0	hSpCas9	negative selection	3661602
23005455	23005478	8	-	26780180	A375	viability (Avana lentiGuide)	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.640388649439387	[]	[]	-1	hSpCas9	negative selection	3661603
23004605	23004628	8	+	26780180	A375	viability (Avana lentiGuide)	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-1.09723504529581	[]	[]	-2	hSpCas9	negative selection	3661604
23006053	23006076	8	-	26780180	A375	viability (Avana lentiGuide)	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	-4.41215628481773	[]	[]	-7	hSpCas9	negative selection	3661605
23007022	23007045	8	+	26780180	A375	viability (Avana lentiGuide)	CCTGGAGGACCCGCTCTGCGCGG	RHOBTB2	ENSG00000008853	-0.610632383081494	[]	[]	-1	hSpCas9	negative selection	3661606
23006797	23006820	8	+	26780180	A375	viability (Avana lentiGuide)	CTACTATGAGACCAGCGTGGTGG	RHOBTB2	ENSG00000008853	6.91639108496435	[]	[]	5	hSpCas9	negative selection	3661607
23004505	23004528	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.20613260157442723	[5]	[6,6]	6	hSpCas9	positive selection	3770209
23005455	23005478	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.25643218782053556	[4]	[3,3]	-4	hSpCas9	positive selection	3770210
23004605	23004628	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.03685605857769854	[4]	[4,4]	0	hSpCas9	positive selection	3770211
23006053	23006076	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	0.2225184513273123	[4]	[4,5]	6	hSpCas9	positive selection	3770212
23007022	23007045	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAGGACCCGCTCTGCGCGG	RHOBTB2	ENSG00000008853	0.40525355235105276	[4]	[6,5]	9	hSpCas9	positive selection	3770213
23006797	23006820	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTATGAGACCAGCGTGGTGG	RHOBTB2	ENSG00000008853	0.033852774797739404	[6]	[6,5]	0	hSpCas9	positive selection	3770214
23004505	23004528	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.06910069696560324	[5]	[5,4]	1	hSpCas9	positive selection	3878816
23005455	23005478	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.7496162136910841	[4]	[2,1]	-7	hSpCas9	positive selection	3878817
23004605	23004628	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.1778293164633828	[5]	[2,5]	-2	hSpCas9	positive selection	3878818
23006053	23006076	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGATGACAGGTGCTCGGGGG	RHOBTB2	ENSG00000008853	-0.30962838536788617	[4]	[2,2]	-4	hSpCas9	positive selection	3878819
23007022	23007045	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAGGACCCGCTCTGCGCGG	RHOBTB2	ENSG00000008853	0.2648654736799052	[5]	[5,4]	7	hSpCas9	positive selection	3878820
23006797	23006820	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTATGAGACCAGCGTGGTGG	RHOBTB2	ENSG00000008853	-0.36927795210085973	[6]	[4,3]	-5	hSpCas9	positive selection	3878821
23004470	23004493	8	+	26780180	A375	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.0966446108134681	[]	[]	-3	hSpCas9	negative selection	3988953
23007353	23007376	8	+	26780180	A375	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.750288025720106	[]	[]	2	hSpCas9	negative selection	3988954
23014724	23014747	8	-	26780180	A375	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	1.13820323100715	[]	[]	6	hSpCas9	negative selection	3988955
23004602	23004625	8	+	26780180	A375	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.921211438459693	[]	[]	4	hSpCas9	negative selection	3988956
23007342	23007365	8	-	26780180	A375	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	1.16255582768897	[]	[]	6	hSpCas9	negative selection	3988957
22995870	22995893	8	-	26780180	A375	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.707200195052247	[]	[]	2	hSpCas9	negative selection	3988958
23004470	23004493	8	+	26780180	HT29	viability (GeCKOv2 library)	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	1.04100032162551	[]	[]	5	hSpCas9	negative selection	4096919
23007353	23007376	8	+	26780180	HT29	viability (GeCKOv2 library)	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	1.3730513398088	[]	[]	7	hSpCas9	negative selection	4096920
23014724	23014747	8	-	26780180	HT29	viability (GeCKOv2 library)	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.799437608995855	[]	[]	3	hSpCas9	negative selection	4096921
23004602	23004625	8	+	26780180	HT29	viability (GeCKOv2 library)	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	1.41789770216919	[]	[]	7	hSpCas9	negative selection	4096922
23007342	23007365	8	-	26780180	HT29	viability (GeCKOv2 library)	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.844623456425568	[]	[]	3	hSpCas9	negative selection	4096923
22995870	22995893	8	-	26780180	HT29	viability (GeCKOv2 library)	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.9540534073277	[]	[]	4	hSpCas9	negative selection	4096924
23007353	23007376	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.19412162159030022	[5]	[3,4]	5	hSpCas9	positive selection	4166359
23014724	23014747	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.29801201694758755	[5]	[3,5]	7	hSpCas9	positive selection	4166360
23007353	23007376	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.25905678490887957	[5]	[4,2,5,0]	2	hSpCas9	positive selection	4230381
23014724	23014747	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	1.0877621871096346	[5]	[5,4,3,5]	7	hSpCas9	positive selection	4230382
23007353	23007376	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.17193335487263744	[3]	[3,2]	3	hSpCas9	positive selection	4294806
22995870	22995893	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.20704531877905336	[1]	[1,0]	-4	hSpCas9	positive selection	4294807
23007342	23007365	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.22836530114565667	[2]	[1,1]	-5	hSpCas9	positive selection	4294808
23004602	23004625	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.10997171902868944	[3]	[3,2]	2	hSpCas9	positive selection	4359061
23014724	23014747	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	-0.326735826050639	[3]	[3,0]	-6	hSpCas9	positive selection	4359062
23004470	23004493	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.022015908025289077	[3]	[4,1]	0	hSpCas9	positive selection	4359063
23004598	23004620	8	-	27760321	OCIAML3	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-1.0986581405172804	[584,467]	[122,279]	-7	hSpCas9	negative selection	4434551
23005455	23005477	8	+	27760321	OCIAML3	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-1.4895508336486172	[760,652]	[181,214]	-8	hSpCas9	negative selection	4434552
23006083	23006105	8	-	27760321	OCIAML3	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.03427882397016513	[311,234]	[198,240]	0	hSpCas9	negative selection	4434553
23006821	23006843	8	-	27760321	OCIAML3	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	-0.6283178473447332	[513,446]	[212,280]	-6	hSpCas9	negative selection	4434554
23007031	23007053	8	-	27760321	OCIAML3	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.9931156054920375	[434,405]	[186,136]	-7	hSpCas9	negative selection	4434555
23004598	23004620	8	-	27760321	OCIAML2	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-0.4222469055452211	[584,467]	[233,423]	-5	hSpCas9	negative selection	4518014
23005455	23005477	8	+	27760321	OCIAML2	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.9969295920382305	[760,652]	[242,341]	-7	hSpCas9	negative selection	4518015
23006083	23006105	8	-	27760321	OCIAML2	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	-0.50766702611567	[311,234]	[105,217]	-5	hSpCas9	negative selection	4518016
23006821	23006843	8	-	27760321	OCIAML2	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	-0.6656303731071467	[513,446]	[199,302]	-6	hSpCas9	negative selection	4518017
23007031	23007053	8	-	27760321	OCIAML2	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.2821412739693323	[434,405]	[256,309]	-3	hSpCas9	negative selection	4518018
23004598	23004620	8	-	27760321	MV411	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-0.8780733873953622	[584,467]	[109,304]	-5	hSpCas9	negative selection	4601477
23005455	23005477	8	+	27760321	MV411	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-1.4330158411090974	[760,652]	[19,400]	-7	hSpCas9	negative selection	4601478
23006083	23006105	8	-	27760321	MV411	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.9639023604220245	[311,234]	[269,467]	7	hSpCas9	negative selection	4601479
23006821	23006843	8	-	27760321	MV411	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.44945278401531485	[513,446]	[343,563]	3	hSpCas9	negative selection	4601480
23007031	23007053	8	-	27760321	MV411	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	0.7948544924574833	[434,405]	[762,58]	6	hSpCas9	negative selection	4601481
23004598	23004620	8	-	27760321	HL60	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-0.015022762125342676	[584,467]	[427,417]	0	hSpCas9	negative selection	4684940
23005455	23005477	8	+	27760321	HL60	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.839971419491939	[760,652]	[310,332]	-7	hSpCas9	negative selection	4684941
23006083	23006105	8	-	27760321	HL60	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.1286282832825446	[311,234]	[166,321]	1	hSpCas9	negative selection	4684942
23006821	23006843	8	-	27760321	HL60	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.173406688522896	[513,446]	[426,456]	2	hSpCas9	negative selection	4684943
23007031	23007053	8	-	27760321	HL60	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.04077802907057021	[434,405]	[319,348]	0	hSpCas9	negative selection	4684944
23004598	23004620	8	-	27760321	HT1080	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-0.20954351331579318	[467,364]	[100,189]	-1	hSpCas9	negative selection	4768403
23005455	23005477	8	+	27760321	HT1080	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	0.47966506327820235	[652,509]	[386,252]	2	hSpCas9	negative selection	4768404
23006083	23006105	8	-	27760321	HT1080	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	2.7380582408553136	[234,183]	[881,200]	9	hSpCas9	negative selection	4768405
23006821	23006843	8	-	27760321	HT1080	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	1.7157189913207598	[446,348]	[821,190]	8	hSpCas9	negative selection	4768406
23007031	23007053	8	-	27760321	HT1080	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.3544375831173682	[405,316]	[62,166]	-2	hSpCas9	negative selection	4768407
23004598	23004620	8	-	27760321	HT29	viability after 7 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	-0.012234224455832388	[467,364]	[674,481,457]	0	hSpCas9	negative selection	4851866
23005455	23005477	8	+	27760321	HT29	viability after 7 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.38394459623785976	[652,509]	[539,619,553]	-5	hSpCas9	negative selection	4851867
23006083	23006105	8	-	27760321	HT29	viability after 7 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	-0.09821314938449943	[234,183]	[259,184,308]	-1	hSpCas9	negative selection	4851868
23006821	23006843	8	-	27760321	HT29	viability after 7 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.29405710442085486	[446,348]	[625,654,600]	4	hSpCas9	negative selection	4851869
23007031	23007053	8	-	27760321	HT29	viability after 7 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.2800588447845851	[405,316]	[324,381,430]	-4	hSpCas9	negative selection	4851870
23004598	23004620	8	-	27760321	HT29	viability after 25 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.38726314381059834	[467,364]	[618,554,700]	4	hSpCas9	negative selection	4935329
23005455	23005477	8	+	27760321	HT29	viability after 25 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.1227780746256667	[652,509]	[530,789,502]	-1	hSpCas9	negative selection	4935330
23006083	23006105	8	-	27760321	HT29	viability after 25 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.3493907644252314	[234,183]	[295,239,387]	4	hSpCas9	negative selection	4935331
23006821	23006843	8	-	27760321	HT29	viability after 25 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.4581975157092074	[446,348]	[607,596,674]	5	hSpCas9	negative selection	4935332
23007031	23007053	8	-	27760321	HT29	viability after 25 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	0.12956931389722065	[405,316]	[319,483,571]	1	hSpCas9	negative selection	4935333
23004598	23004620	8	-	27760321	HT29	viability after 22 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.7055453297450522	[467,364]	[984,691,671]	7	hSpCas9	negative selection	5018792
23005455	23005477	8	+	27760321	HT29	viability after 22 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	0.22053360097818264	[652,509]	[755,667,927]	2	hSpCas9	negative selection	5018793
23006083	23006105	8	-	27760321	HT29	viability after 22 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.6322797628442743	[234,183]	[388,261,475]	7	hSpCas9	negative selection	5018794
23006821	23006843	8	-	27760321	HT29	viability after 22 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.36818621688183184	[446,348]	[506,472,805]	4	hSpCas9	negative selection	5018795
23007031	23007053	8	-	27760321	HT29	viability after 22 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	0.06015410397458387	[405,316]	[338,403,567]	0	hSpCas9	negative selection	5018796
23004598	23004620	8	-	27760321	HT29	viability after 19 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.5440121255900126	[467,364]	[1073,629,428]	5	hSpCas9	negative selection	5102255
23005455	23005477	8	+	27760321	HT29	viability after 19 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.16634531754912318	[652,509]	[696,539,552]	-1	hSpCas9	negative selection	5102256
23006083	23006105	8	-	27760321	HT29	viability after 19 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	1.2489139131110263	[234,183]	[333,307,1023]	9	hSpCas9	negative selection	5102257
23006821	23006843	8	-	27760321	HT29	viability after 19 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.3339801706681008	[446,348]	[470,714,525]	3	hSpCas9	negative selection	5102258
23007031	23007053	8	-	27760321	HT29	viability after 19 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	0.030358513495537576	[405,316]	[424,265,569]	0	hSpCas9	negative selection	5102259
23004598	23004620	8	-	27760321	HT29	viability after 16 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.03924640395044268	[467,364]	[274,635,501]	0	hSpCas9	negative selection	5185718
23005455	23005477	8	+	27760321	HT29	viability after 16 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.3918162211214694	[652,509]	[418,506,553]	-4	hSpCas9	negative selection	5185719
23006083	23006105	8	-	27760321	HT29	viability after 16 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.14675962264715192	[234,183]	[263,67,451]	1	hSpCas9	negative selection	5185720
23006821	23006843	8	-	27760321	HT29	viability after 16 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.5645762524501889	[446,348]	[714,770,491]	6	hSpCas9	negative selection	5185721
23007031	23007053	8	-	27760321	HT29	viability after 16 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.2158662061046463	[405,316]	[398,366,282]	-2	hSpCas9	negative selection	5185722
23004598	23004620	8	-	27760321	HT29	viability after 13 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.35857758657244665	[467,364]	[629,551,672]	4	hSpCas9	negative selection	5269181
23005455	23005477	8	+	27760321	HT29	viability after 13 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.12232134818848095	[652,509]	[598,873,399]	-1	hSpCas9	negative selection	5269182
23006083	23006105	8	-	27760321	HT29	viability after 13 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.5115578223491767	[234,183]	[292,302,437]	6	hSpCas9	negative selection	5269183
23006821	23006843	8	-	27760321	HT29	viability after 13 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.21685960922728462	[446,348]	[712,540,365]	2	hSpCas9	negative selection	5269184
23007031	23007053	8	-	27760321	HT29	viability after 13 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.14772835978964502	[405,316]	[451,313,369]	-2	hSpCas9	negative selection	5269185
23004598	23004620	8	-	27760321	HT29	viability after 10 days	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.03982884588979871	[467,364]	[529,544,528]	0	hSpCas9	negative selection	5352644
23005455	23005477	8	+	27760321	HT29	viability after 10 days	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	-0.21534482412666056	[652,509]	[645,694,538]	-3	hSpCas9	negative selection	5352645
23006083	23006105	8	-	27760321	HT29	viability after 10 days	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	0.5756444628915116	[234,183]	[303,414,449]	7	hSpCas9	negative selection	5352646
23006821	23006843	8	-	27760321	HT29	viability after 10 days	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	0.35063216742322345	[446,348]	[633,455,801]	5	hSpCas9	negative selection	5352647
23007031	23007053	8	-	27760321	HT29	viability after 10 days	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.10444015385337856	[405,316]	[395,300,555]	-1	hSpCas9	negative selection	5352648
23004598	23004620	8	-	27760321	MOLM13	viability	CACACACGATATTGGTCGATGG	RHOBTB2	ENSG00000008853	0.21137073778648435	[584,467]	[369,317]	1	hSpCas9	negative selection	5436107
23005455	23005477	8	+	27760321	MOLM13	viability	CCGTCGCTTTGCTTATGGGAGG	RHOBTB2	ENSG00000008853	0.11653768672484555	[760,652]	[186,638]	0	hSpCas9	negative selection	5436108
23006083	23006105	8	-	27760321	MOLM13	viability	AGCGTAGCGCAGGTCCAACTGG	RHOBTB2	ENSG00000008853	-0.0458788756301437	[311,234]	[144,150]	0	hSpCas9	negative selection	5436109
23006821	23006843	8	-	27760321	MOLM13	viability	GACGTCCTTGATGCCGAACTGG	RHOBTB2	ENSG00000008853	-0.4612942890626941	[513,446]	[109,269]	-3	hSpCas9	negative selection	5436110
23007031	23007053	8	-	27760321	MOLM13	viability	GATGACGTCCGCGCAGAGCGGG	RHOBTB2	ENSG00000008853	-0.20032160391562667	[434,405]	[70,321]	-1	hSpCas9	negative selection	5436111
22999539	22999562	8	+	27661255	K562	viability	GCAGTGGGCGGGGCCCGTCACGG	RHOBTB2	ENSG00000008853	-0.13198725808664286	[888,793]	[625,604]	-4	dCas9-KRAB	negative selection	5507351
22999840	22999863	8	+	27661255	K562	viability	GGGCGATGCTGATCCGGAAGGGG	RHOBTB2	ENSG00000008853	-0.04755181012920495	[905,840]	[722,635]	-2	dCas9-KRAB	negative selection	5507352
22999814	22999837	8	-	27661255	K562	viability	GCGCCAGGCGCCCAATGTCACGG	RHOBTB2	ENSG00000008853	0.4225952005269549	[128,136]	[165,121]	9	dCas9-KRAB	negative selection	5507353
22999889	22999912	8	-	27661255	K562	viability	GCCGGACGTGGGCCCAGGAGCGG	RHOBTB2	ENSG00000008853	-0.4533119675993935	[347,343]	[209,194]	-7	dCas9-KRAB	negative selection	5507354
22999900	22999923	8	-	27661255	K562	viability	GGGCAGCCCAGGCCGGACGTGGG	RHOBTB2	ENSG00000008853	0.16550614725972967	[507,474]	[462,421]	6	dCas9-KRAB	negative selection	5507355
22999920	22999943	8	-	27661255	K562	viability	GCCACTCAGAAACTCCGGCAGGG	RHOBTB2	ENSG00000008853	0.0650383110135877	[200,345]	[234,218]	2	dCas9-KRAB	negative selection	5507356
23000149	23000172	8	-	27661255	K562	viability	GCGGAGCGGCGCGTCTGCAAGGG	RHOBTB2	ENSG00000008853	0.1564874295410345	[929,1111]	[958,860]	5	dCas9-KRAB	negative selection	5507357
23007353	23007376	8	+	27260156	BXPC3	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.08388379850725891	[739]	[665,786,725,1153]	1	hSpCas9	negative selection	5567266
22995870	22995893	8	-	27260156	BXPC3	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.12005480193837959	[177]	[238,175,169,221]	2	hSpCas9	negative selection	5567267
23007342	23007365	8	-	27260156	BXPC3	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.13745253119699946	[393]	[399,343,395,351]	-3	hSpCas9	negative selection	5567268
23004602	23004625	8	+	27260156	BXPC3	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.04855565653423122	[777]	[796,746,1005,819]	1	hSpCas9	negative selection	5631521
23014724	23014747	8	-	27260156	BXPC3	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.11040826689947753	[547]	[630,558,587,703]	2	hSpCas9	negative selection	5631522
23004470	23004493	8	+	27260156	BXPC3	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.14252781217065458	[842]	[684,692,847,1007]	-3	hSpCas9	negative selection	5631523
23007353	23007376	8	+	27260156	A673	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.003767412355659472	[739]	[979,777,875,943]	0	hSpCas9	negative selection	5688517
22995870	22995893	8	-	27260156	A673	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.15003693587019695	[177]	[256,220,189,285]	3	hSpCas9	negative selection	5688518
23007342	23007365	8	-	27260156	A673	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.0510484986366157	[393]	[546,484,482,448]	1	hSpCas9	negative selection	5688519
23004602	23004625	8	+	27260156	A673	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.013085315904942663	[777]	[1166,851,807,972]	0	hSpCas9	negative selection	5752772
23014724	23014747	8	-	27260156	A673	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2875531464114244	[547]	[918,773,783,744]	6	hSpCas9	negative selection	5752773
23004470	23004493	8	+	27260156	A673	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.24598208529081056	[842]	[862,724,956,871]	-6	hSpCas9	negative selection	5752774
23007353	23007376	8	+	27260156	A375	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.280703617249377	[739]	[1084,1512,950,747]	4	hSpCas9	negative selection	5809768
22995870	22995893	8	-	27260156	A375	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.3515000455738724	[177]	[392,180,170,299]	5	hSpCas9	negative selection	5809769
23007342	23007365	8	-	27260156	A375	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.03354430615835832	[393]	[378,647,258,603]	0	hSpCas9	negative selection	5809770
23004602	23004625	8	+	27260156	A375	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.2694898558139286	[777]	[1192,1399,1081,782]	4	hSpCas9	negative selection	5874023
23014724	23014747	8	-	27260156	A375	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2729244038805027	[547]	[896,695,699,785]	4	hSpCas9	negative selection	5874024
23004470	23004493	8	+	27260156	A375	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.176910510153802	[842]	[897,1385,1259,958]	2	hSpCas9	negative selection	5874025
23007353	23007376	8	+	27260156	COLO741	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	-0.21035821589557202	[739]	[1171,626,689]	-4	hSpCas9	negative selection	5931019
22995870	22995893	8	-	27260156	COLO741	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.2097252836577339	[177]	[340,219,235]	4	hSpCas9	negative selection	5931020
23007342	23007365	8	-	27260156	COLO741	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.07417468745906924	[393]	[665,445,490]	1	hSpCas9	negative selection	5931021
23004602	23004625	8	+	27260156	COLO741	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.029107774933791908	[777]	[1026,856,1035]	0	hSpCas9	negative selection	5995274
23014724	23014747	8	-	27260156	COLO741	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.17618908231987568	[547]	[900,817,670]	4	hSpCas9	negative selection	5995275
23004470	23004493	8	+	27260156	COLO741	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.01344606394501291	[842]	[1285,918,1015]	0	hSpCas9	negative selection	5995276
23007353	23007376	8	+	27260156	CAL120	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.4978723899194255	[739]	[1615,974,1355]	7	hSpCas9	negative selection	6052270
22995870	22995893	8	-	27260156	CAL120	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.0030761487984198865	[177]	[196,275,186]	0	hSpCas9	negative selection	6052271
23007342	23007365	8	-	27260156	CAL120	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.08127968433031041	[393]	[701,503,379]	1	hSpCas9	negative selection	6052272
23004602	23004625	8	+	27260156	CAL120	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.12942854548423444	[777]	[1594,814,850]	2	hSpCas9	negative selection	6116525
23014724	23014747	8	-	27260156	CAL120	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.026006690995248355	[547]	[674,889,517]	0	hSpCas9	negative selection	6116526
23004470	23004493	8	+	27260156	CAL120	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.17042676041683436	[842]	[1202,1129,1210]	2	hSpCas9	negative selection	6116527
23007353	23007376	8	+	27260156	CADOES1	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	-0.01305638586697877	[739]	[634,692,725,673]	0	hSpCas9	negative selection	6173521
22995870	22995893	8	-	27260156	CADOES1	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.31113606358813195	[177]	[164,172,318,162]	5	hSpCas9	negative selection	6173522
23007342	23007365	8	-	27260156	CADOES1	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.004787624453070127	[393]	[420,455,345,232]	0	hSpCas9	negative selection	6173523
23004602	23004625	8	+	27260156	CADOES1	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.28515592007289703	[777]	[910,733,1138,736]	5	hSpCas9	negative selection	6237776
23014724	23014747	8	-	27260156	CADOES1	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.261357027464508	[547]	[574,526,818,518]	4	hSpCas9	negative selection	6237777
23004470	23004493	8	+	27260156	CADOES1	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.39688862716760726	[842]	[612,459,573,739]	-6	hSpCas9	negative selection	6237778
23007353	23007376	8	+	27260156	EWS502	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.1315788374808331	[739]	[850,883,817,878]	2	hSpCas9	negative selection	6294772
22995870	22995893	8	-	27260156	EWS502	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.2441513527699557	[177]	[131,87,276,145]	-4	hSpCas9	negative selection	6294773
23007342	23007365	8	-	27260156	EWS502	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.16222661963357926	[393]	[482,452,375,557]	3	hSpCas9	negative selection	6294774
23004602	23004625	8	+	27260156	EWS502	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.18813612094763843	[777]	[791,1006,964,1007]	3	hSpCas9	negative selection	6359027
23014724	23014747	8	-	27260156	EWS502	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.17115435263426493	[547]	[541,826,598,648]	3	hSpCas9	negative selection	6359028
23004470	23004493	8	+	27260156	EWS502	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.10381686083481945	[842]	[687,887,812,954]	-2	hSpCas9	negative selection	6359029
23007353	23007376	8	+	27260156	EW8	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.2842609903104263	[739]	[712,916,577,735]	5	hSpCas9	negative selection	6416023
22995870	22995893	8	-	27260156	EW8	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.21242583514072444	[177]	[195,84,90,138]	-4	hSpCas9	negative selection	6416024
23007342	23007365	8	-	27260156	EW8	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.08219294030385171	[393]	[350,286,313,256]	-1	hSpCas9	negative selection	6416025
23004602	23004625	8	+	27260156	EW8	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.015862321906954358	[777]	[691,588,539,692]	0	hSpCas9	negative selection	6480278
23014724	23014747	8	-	27260156	EW8	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2927480369080243	[547]	[505,647,447,584]	5	hSpCas9	negative selection	6480279
23004470	23004493	8	+	27260156	EW8	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.1026361526827716	[842]	[732,635,576,617]	-2	hSpCas9	negative selection	6480280
23007353	23007376	8	+	27260156	CORL105	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.30316595021886394	[739]	[1032,903,1447,951]	5	hSpCas9	negative selection	6537274
22995870	22995893	8	-	27260156	CORL105	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.1639716986848072	[177]	[311,209,244,171]	3	hSpCas9	negative selection	6537275
23007342	23007365	8	-	27260156	CORL105	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.07536538011393357	[393]	[372,514,404,448]	-1	hSpCas9	negative selection	6537276
23004602	23004625	8	+	27260156	CORL105	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.11178304626498825	[777]	[861,884,1126,1081]	2	hSpCas9	negative selection	6601529
23014724	23014747	8	-	27260156	CORL105	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.13091010648906892	[547]	[690,574,963,622]	2	hSpCas9	negative selection	6601530
23004470	23004493	8	+	27260156	CORL105	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.11842445356953568	[842]	[934,798,903,999]	-2	hSpCas9	negative selection	6601531
23007353	23007376	8	+	27260156	HS294T	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.3398761266788741	[739]	[276,349,371,475]	4	hSpCas9	negative selection	6658525
22995870	22995893	8	-	27260156	HS294T	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.7795237076003377	[177]	[85,72,208,106]	8	hSpCas9	negative selection	6658526
23007342	23007365	8	-	27260156	HS294T	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.23876661406789762	[393]	[115,252,163,190]	3	hSpCas9	negative selection	6658527
23004602	23004625	8	+	27260156	HS294T	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.37081200429984285	[777]	[371,468,290,427]	5	hSpCas9	negative selection	6722780
23014724	23014747	8	-	27260156	HS294T	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.48047278317254183	[547]	[385,287,227,265]	6	hSpCas9	negative selection	6722781
23004470	23004493	8	+	27260156	HS294T	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.35183211390209046	[842]	[216,166,345,305]	-5	hSpCas9	negative selection	6722782
23007353	23007376	8	+	27260156	HCC44	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.22055525776474139	[739]	[1253,671,1011,1027]	3	hSpCas9	negative selection	6779776
22995870	22995893	8	-	27260156	HCC44	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.2633436670475855	[177]	[215,329,280,132]	4	hSpCas9	negative selection	6779777
23007342	23007365	8	-	27260156	HCC44	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.35088648056977023	[393]	[637,485,473,668]	6	hSpCas9	negative selection	6779778
23004602	23004625	8	+	27260156	HCC44	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.013301796936884491	[777]	[987,701,854,963]	0	hSpCas9	negative selection	6844031
23014724	23014747	8	-	27260156	HCC44	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.10567578445271636	[547]	[749,435,793,741]	1	hSpCas9	negative selection	6844032
23004470	23004493	8	+	27260156	HCC44	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.22448201271034207	[842]	[708,704,848,999]	-4	hSpCas9	negative selection	6844033
23007353	23007376	8	+	27260156	G402	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.0262746920041399	[739]	[1062,746,991,884]	0	hSpCas9	negative selection	6901027
22995870	22995893	8	-	27260156	G402	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.33423831399317194	[177]	[204,145,196,144]	-4	hSpCas9	negative selection	6901028
23007342	23007365	8	-	27260156	G402	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.20352475000601805	[393]	[444,550,369,318]	-3	hSpCas9	negative selection	6901029
23004602	23004625	8	+	27260156	G402	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.08261969259966118	[777]	[1206,933,934,967]	1	hSpCas9	negative selection	6965282
23014724	23014747	8	-	27260156	G402	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	-0.20716078647778383	[547]	[736,424,576,588]	-3	hSpCas9	negative selection	6965283
23004470	23004493	8	+	27260156	G402	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.3035052762700551	[842]	[860,1167,637,693]	-4	hSpCas9	negative selection	6965284
23007353	23007376	8	+	27260156	L33	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.36247367425045574	[739]	[953,320,588,1128]	7	hSpCas9	negative selection	7022278
22995870	22995893	8	-	27260156	L33	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.38408660226615243	[177]	[234,123,143,162]	7	hSpCas9	negative selection	7022279
23007342	23007365	8	-	27260156	L33	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.1355481899064599	[393]	[365,200,263,455]	3	hSpCas9	negative selection	7022280
23004602	23004625	8	+	27260156	L33	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.2003828283421515	[777]	[692,228,452,734]	-4	hSpCas9	negative selection	7086533
23014724	23014747	8	-	27260156	L33	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	-0.13511782430093305	[547]	[466,230,309,472]	-3	hSpCas9	negative selection	7086534
23004470	23004493	8	+	27260156	L33	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.2946684389157588	[842]	[864,249,396,637]	-6	hSpCas9	negative selection	7086535
23007353	23007376	8	+	27260156	K562	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.2472182670207147	[739]	[772,509,1048,768]	3	hSpCas9	negative selection	7143529
22995870	22995893	8	-	27260156	K562	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	1.030277818322702	[177]	[158,515,345,270]	9	hSpCas9	negative selection	7143530
23007342	23007365	8	-	27260156	K562	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.10184359550689343	[393]	[415,455,390,81]	-1	hSpCas9	negative selection	7143531
23004602	23004625	8	+	27260156	K562	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.16162777834165298	[777]	[799,796,848,656]	2	hSpCas9	negative selection	7207784
23014724	23014747	8	-	27260156	K562	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.6671447503136879	[547]	[1045,703,813,564]	8	hSpCas9	negative selection	7207785
23004470	23004493	8	+	27260156	K562	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.20777219788329226	[842]	[823,922,764,931]	2	hSpCas9	negative selection	7207786
23007353	23007376	8	+	27260156	HT29	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.2568882809105959	[739]	[1205,1112,991,1002]	5	hSpCas9	negative selection	7264780
22995870	22995893	8	-	27260156	HT29	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.13180700045047566	[177]	[196,161,269,160]	-3	hSpCas9	negative selection	7264781
23007342	23007365	8	-	27260156	HT29	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.11529950385158003	[393]	[538,560,622,371]	2	hSpCas9	negative selection	7264782
23004602	23004625	8	+	27260156	HT29	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.07086051862196152	[777]	[1117,1006,909,620]	-1	hSpCas9	negative selection	7329035
23014724	23014747	8	-	27260156	HT29	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.3084115067948342	[547]	[1029,750,785,745]	6	hSpCas9	negative selection	7329036
23004470	23004493	8	+	27260156	HT29	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.2203631058747373	[842]	[1023,890,1015,624]	-4	hSpCas9	negative selection	7329037
23007353	23007376	8	+	27260156	MHHES1	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.33538623854958916	[739]	[1570,1091,772,856]	6	hSpCas9	negative selection	7386031
22995870	22995893	8	-	27260156	MHHES1	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.4187038823654903	[177]	[339,328,214,209]	7	hSpCas9	negative selection	7386032
23007342	23007365	8	-	27260156	MHHES1	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.2654128486812227	[393]	[489,498,859,316]	5	hSpCas9	negative selection	7386033
23004602	23004625	8	+	27260156	MHHES1	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.2993823245520375	[777]	[971,1232,893,1168]	5	hSpCas9	negative selection	7450286
23014724	23014747	8	-	27260156	MHHES1	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.38867271222721544	[547]	[1074,881,683,648]	7	hSpCas9	negative selection	7450287
23004470	23004493	8	+	27260156	MHHES1	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.14224110117459543	[842]	[1085,900,720,765]	-3	hSpCas9	negative selection	7450288
23007353	23007376	8	+	27260156	MEWO	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.044125224978865396	[739]	[714,615,810]	1	hSpCas9	negative selection	7507282
22995870	22995893	8	-	27260156	MEWO	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.00821172133096093	[177]	[227,193,91]	0	hSpCas9	negative selection	7507283
23007342	23007365	8	-	27260156	MEWO	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.059315246370102076	[393]	[485,364,320]	1	hSpCas9	negative selection	7507284
23004602	23004625	8	+	27260156	MEWO	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.014013602175412587	[777]	[812,707,698]	0	hSpCas9	negative selection	7571537
23014724	23014747	8	-	27260156	MEWO	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.23620647834607822	[547]	[615,579,617]	5	hSpCas9	negative selection	7571538
23004470	23004493	8	+	27260156	MEWO	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.1329916555583044	[842]	[988,674,545]	-3	hSpCas9	negative selection	7571539
23007353	23007376	8	+	27260156	LNCAPCLONEFGC	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.2555752340729692	[739]	[921,706,811,764]	4	hSpCas9	negative selection	7628533
22995870	22995893	8	-	27260156	LNCAPCLONEFGC	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.2725808028280945	[177]	[197,151,236,200]	4	hSpCas9	negative selection	7628534
23007342	23007365	8	-	27260156	LNCAPCLONEFGC	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.3092744979889007	[393]	[303,287,350,217]	-5	hSpCas9	negative selection	7628535
23004602	23004625	8	+	27260156	LNCAPCLONEFGC	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.33894316077368947	[777]	[682,872,882,1129]	5	hSpCas9	negative selection	7692788
23014724	23014747	8	-	27260156	LNCAPCLONEFGC	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.01846751753589071	[547]	[431,569,584,432]	0	hSpCas9	negative selection	7692789
23004470	23004493	8	+	27260156	LNCAPCLONEFGC	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.1722873582503548	[842]	[1083,618,1048,728]	2	hSpCas9	negative selection	7692790
23007353	23007376	8	+	27260156	PANC0327	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.3497070198798127	[739]	[1052,722,883,722]	5	hSpCas9	negative selection	7749784
22995870	22995893	8	-	27260156	PANC0327	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.40324427419156295	[177]	[170,69,193,53]	-5	hSpCas9	negative selection	7749785
23007342	23007365	8	-	27260156	PANC0327	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.06386087955490985	[393]	[549,343,263,322]	0	hSpCas9	negative selection	7749786
23004602	23004625	8	+	27260156	PANC0327	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.14624766328559524	[777]	[452,447,956,648]	-2	hSpCas9	negative selection	7814039
23014724	23014747	8	-	27260156	PANC0327	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.60776422545947	[547]	[916,568,862,654]	8	hSpCas9	negative selection	7814040
23004470	23004493	8	+	27260156	PANC0327	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.027904598401771175	[842]	[986,362,1025,630]	0	hSpCas9	negative selection	7814041
23007353	23007376	8	+	27260156	NCIH2009	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.6918880734096788	[739]	[1732,1396,1894]	8	hSpCas9	negative selection	7871035
22995870	22995893	8	-	27260156	NCIH2009	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.35670307316464744	[177]	[341,178,440]	5	hSpCas9	negative selection	7871036
23007342	23007365	8	-	27260156	NCIH2009	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.33919623566444856	[393]	[956,612,570]	4	hSpCas9	negative selection	7871037
23004602	23004625	8	+	27260156	NCIH2009	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.17407246780231778	[777]	[1486,1147,1094]	2	hSpCas9	negative selection	7935290
23014724	23014747	8	-	27260156	NCIH2009	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.4973523037862485	[547]	[1162,1179,911]	7	hSpCas9	negative selection	7935291
23004470	23004493	8	+	27260156	NCIH2009	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.04961523295651005	[842]	[1140,1006,1266]	0	hSpCas9	negative selection	7935292
23007353	23007376	8	+	27260156	NCIH1373	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.893195906318897	[739]	[1788,1555,1319,401]	8	hSpCas9	negative selection	7992286
22995870	22995893	8	-	27260156	NCIH1373	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	1.3810657183643797	[177]	[256,449,758,150]	9	hSpCas9	negative selection	7992287
23007342	23007365	8	-	27260156	NCIH1373	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.279497968560548	[393]	[407,292,505,65]	-3	hSpCas9	negative selection	7992288
23004602	23004625	8	+	27260156	NCIH1373	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.2994537775057935	[777]	[918,1056,1089,316]	3	hSpCas9	negative selection	8056541
23014724	23014747	8	-	27260156	NCIH1373	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	1.0494069521171698	[547]	[2532,754,1020,265]	9	hSpCas9	negative selection	8056542
23004470	23004493	8	+	27260156	NCIH1373	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.07457817627001118	[842]	[640,894,1178,321]	0	hSpCas9	negative selection	8056543
23007353	23007376	8	+	27260156	PATU8902	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.5479289598761174	[739]	[1308,1369,1573,1778]	6	hSpCas9	negative selection	8113537
22995870	22995893	8	-	27260156	PATU8902	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.5977647649520504	[177]	[182,419,245,726]	6	hSpCas9	negative selection	8113538
23007342	23007365	8	-	27260156	PATU8902	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.5218041687525491	[393]	[862,658,362,1447]	5	hSpCas9	negative selection	8113539
23004602	23004625	8	+	27260156	PATU8902	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.6755938359797897	[777]	[2413,1119,1297,2238]	7	hSpCas9	negative selection	8177792
23014724	23014747	8	-	27260156	PATU8902	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.5209772706639015	[547]	[1091,598,982,1810]	5	hSpCas9	negative selection	8177793
23004470	23004493	8	+	27260156	PATU8902	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.1459204353473902	[842]	[633,1092,1169,1350]	-1	hSpCas9	negative selection	8177794
23007353	23007376	8	+	27260156	PANC1	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.13989907249184153	[739]	[544,873,625,770]	2	hSpCas9	negative selection	8234788
22995870	22995893	8	-	27260156	PANC1	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.4089382147020749	[177]	[227,173,150,241]	6	hSpCas9	negative selection	8234789
23007342	23007365	8	-	27260156	PANC1	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.04527160512363354	[393]	[401,409,237,278]	0	hSpCas9	negative selection	8234790
23004602	23004625	8	+	27260156	PANC1	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.09287569852765032	[777]	[649,983,683,596]	1	hSpCas9	negative selection	8299043
23014724	23014747	8	-	27260156	PANC1	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2908066154004135	[547]	[549,646,691,442]	5	hSpCas9	negative selection	8299044
23004470	23004493	8	+	27260156	PANC1	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.038931988123780736	[842]	[805,758,704,568]	0	hSpCas9	negative selection	8299045
23007353	23007376	8	+	27260156	PANC0813	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.43048121243603643	[739]	[1087,1174,1147,1259]	7	hSpCas9	negative selection	8356039
22995870	22995893	8	-	27260156	PANC0813	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.4508639385546044	[177]	[444,229,298,188]	7	hSpCas9	negative selection	8356040
23007342	23007365	8	-	27260156	PANC0813	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.17272761755360158	[393]	[519,480,444,632]	3	hSpCas9	negative selection	8356041
23004602	23004625	8	+	27260156	PANC0813	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.058710460025901856	[777]	[977,745,941,1131]	1	hSpCas9	negative selection	8420294
23014724	23014747	8	-	27260156	PANC0813	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2508004048882183	[547]	[692,1084,574,704]	4	hSpCas9	negative selection	8420295
23004470	23004493	8	+	27260156	PANC0813	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	0.03629935698638154	[842]	[1124,801,1163,981]	0	hSpCas9	negative selection	8420296
23007353	23007376	8	+	27260156	RDES	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.02099430192159879	[739]	[682,829,833,1168]	0	hSpCas9	negative selection	8477290
22995870	22995893	8	-	27260156	RDES	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.02380797740725682	[177]	[253,157,148,231]	0	hSpCas9	negative selection	8477291
23007342	23007365	8	-	27260156	RDES	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	-0.2430347248736246	[393]	[297,362,374,525]	-4	hSpCas9	negative selection	8477292
23004602	23004625	8	+	27260156	RDES	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.19792123603773526	[777]	[736,965,1010,1502]	3	hSpCas9	negative selection	8541545
23014724	23014747	8	-	27260156	RDES	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2104800525295466	[547]	[747,594,784,782]	3	hSpCas9	negative selection	8541546
23004470	23004493	8	+	27260156	RDES	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.3020929222399902	[842]	[798,658,730,963]	-5	hSpCas9	negative selection	8541547
23007353	23007376	8	+	27260156	PC3	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.1424149347417959	[739]	[383,911,1359,938]	3	hSpCas9	negative selection	8598541
22995870	22995893	8	-	27260156	PC3	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.38207509393712735	[177]	[61,290,520,222]	7	hSpCas9	negative selection	8598542
23007342	23007365	8	-	27260156	PC3	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.23062203221152544	[393]	[366,390,646,501]	5	hSpCas9	negative selection	8598543
23004602	23004625	8	+	27260156	PC3	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.09572012112533501	[777]	[431,691,1283,777]	-2	hSpCas9	negative selection	8662796
23014724	23014747	8	-	27260156	PC3	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.20970779153921248	[547]	[428,598,1064,626]	4	hSpCas9	negative selection	8662797
23004470	23004493	8	+	27260156	PC3	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.18666572512331625	[842]	[627,543,1325,645]	-4	hSpCas9	negative selection	8662798
23007353	23007376	8	+	27260156	PATU8988T	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.21973578557351303	[739]	[514,964,1020,839]	4	hSpCas9	negative selection	8719792
22995870	22995893	8	-	27260156	PATU8988T	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.014325700221252458	[177]	[152,174,101,273]	0	hSpCas9	negative selection	8719793
23007342	23007365	8	-	27260156	PATU8988T	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.03169999071159266	[393]	[565,461,264,261]	0	hSpCas9	negative selection	8719794
23004602	23004625	8	+	27260156	PATU8988T	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.09493729875166257	[777]	[1172,585,754,666]	1	hSpCas9	negative selection	8784047
23014724	23014747	8	-	27260156	PATU8988T	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.26279032378091277	[547]	[580,833,359,801]	4	hSpCas9	negative selection	8784048
23004470	23004493	8	+	27260156	PATU8988T	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.45894002469242134	[842]	[726,629,379,643]	-6	hSpCas9	negative selection	8784049
23007353	23007376	8	+	27260156	T47D	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.19070406097635018	[739]	[991,890,1014,1046]	4	hSpCas9	negative selection	8841043
22995870	22995893	8	-	27260156	T47D	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.1666908041887225	[177]	[206,205,232,288]	3	hSpCas9	negative selection	8841044
23007342	23007365	8	-	27260156	T47D	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.04406904834103462	[393]	[491,461,465,473]	0	hSpCas9	negative selection	8841045
23004602	23004625	8	+	27260156	T47D	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.0035196569833333413	[777]	[1042,776,963,840]	0	hSpCas9	negative selection	8905298
23014724	23014747	8	-	27260156	T47D	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.3672409874843764	[547]	[846,687,774,1001]	7	hSpCas9	negative selection	8905299
23004470	23004493	8	+	27260156	T47D	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.12610750044290542	[842]	[859,895,936,905]	-3	hSpCas9	negative selection	8905300
23007353	23007376	8	+	27260156	SU8686	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.2608260583182429	[739]	[676,806,874,1241]	4	hSpCas9	negative selection	8962294
22995870	22995893	8	-	27260156	SU8686	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.22466351575932997	[177]	[209,109,270,253]	4	hSpCas9	negative selection	8962295
23007342	23007365	8	-	27260156	SU8686	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.35385548972360964	[393]	[561,460,392,585]	6	hSpCas9	negative selection	8962296
23004602	23004625	8	+	27260156	SU8686	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.05835591234273563	[777]	[767,705,977,770]	1	hSpCas9	negative selection	9026549
23014724	23014747	8	-	27260156	SU8686	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.1106191965448125	[547]	[525,540,630,671]	1	hSpCas9	negative selection	9026550
23004470	23004493	8	+	27260156	SU8686	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.1353497212047191	[842]	[666,624,639,1202]	-2	hSpCas9	negative selection	9026551
23007353	23007376	8	+	27260156	SKES1	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.3065658853527452	[739]	[937,1037,820,869]	6	hSpCas9	negative selection	9083545
22995870	22995893	8	-	27260156	SKES1	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.3305622201092633	[177]	[245,253,161,234]	7	hSpCas9	negative selection	9083546
23007342	23007365	8	-	27260156	SKES1	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.36273397318588724	[393]	[592,534,365,535]	7	hSpCas9	negative selection	9083547
23004602	23004625	8	+	27260156	SKES1	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.11116323920136029	[777]	[1112,740,819,711]	2	hSpCas9	negative selection	9147800
23014724	23014747	8	-	27260156	SKES1	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.4686698507721452	[547]	[777,1103,656,549]	8	hSpCas9	negative selection	9147801
23004470	23004493	8	+	27260156	SKES1	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.13038345613893476	[842]	[730,965,729,668]	-3	hSpCas9	negative selection	9147802
23007353	23007376	8	+	27260156	TOV112D	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.0271671011617437	[739]	[733,780,708,798]	0	hSpCas9	negative selection	9204796
22995870	22995893	8	-	27260156	TOV112D	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.29468556895588205	[177]	[164,231,289,186]	5	hSpCas9	negative selection	9204797
23007342	23007365	8	-	27260156	TOV112D	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.1360149196104643	[393]	[382,533,431,405]	2	hSpCas9	negative selection	9204798
23004602	23004625	8	+	27260156	TOV112D	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.24387804273235802	[777]	[794,1305,897,777]	4	hSpCas9	negative selection	9269051
23014724	23014747	8	-	27260156	TOV112D	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.33403523664214885	[547]	[460,960,516,868]	6	hSpCas9	negative selection	9269052
23004470	23004493	8	+	27260156	TOV112D	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.06622306628465646	[842]	[742,1205,729,642]	-1	hSpCas9	negative selection	9269053
23007353	23007376	8	+	27260156	TC71	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	0.1291203593917689	[739]	[911,879,838,836]	3	hSpCas9	negative selection	9326047
22995870	22995893	8	-	27260156	TC71	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	0.0179640638237466	[177]	[211,177,193,187]	0	hSpCas9	negative selection	9326048
23007342	23007365	8	-	27260156	TC71	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.18096737414632286	[393]	[473,435,511,492]	4	hSpCas9	negative selection	9326049
23004602	23004625	8	+	27260156	TC71	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	-0.112328415349495	[777]	[703,791,717,881]	-3	hSpCas9	negative selection	9390302
23014724	23014747	8	-	27260156	TC71	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.2900969433548406	[547]	[688,720,741,720]	7	hSpCas9	negative selection	9390303
23004470	23004493	8	+	27260156	TC71	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.17373838473933834	[842]	[688,755,804,966]	-4	hSpCas9	negative selection	9390304
23007353	23007376	8	+	27260156	TC32	viability	ATCTTACGGGGCAACGGAACAGG	RHOBTB2	ENSG00000008853	-0.07945637494253266	[739]	[642,446,738,872]	-1	hSpCas9	negative selection	9447298
22995870	22995893	8	-	27260156	TC32	viability	GGCTACTAACCGCGCTTTCATGG	RHOBTB2	ENSG00000008853	-0.661870809904886	[177]	[131,61,79,153]	-8	hSpCas9	negative selection	9447299
23007342	23007365	8	-	27260156	TC32	viability	GCCCCGTAAGATCCCGTCGCTGG	RHOBTB2	ENSG00000008853	0.4392433571205165	[393]	[456,561,585,357]	7	hSpCas9	negative selection	9447300
23004602	23004625	8	+	27260156	TC32	viability	CGACCAATATCGTGTGTGCCAGG	RHOBTB2	ENSG00000008853	0.42120576359041695	[777]	[770,945,1123,1082]	7	hSpCas9	negative selection	9511553
23014724	23014747	8	-	27260156	TC32	viability	CATCGATGTCCACCATCATCTGG	RHOBTB2	ENSG00000008853	0.14305612075267277	[547]	[611,313,821,632]	2	hSpCas9	negative selection	9511554
23004470	23004493	8	+	27260156	TC32	viability	AGAGACCATCAAGTGCGTTGTGG	RHOBTB2	ENSG00000008853	-0.40128861672361654	[842]	[649,416,780,609]	-6	hSpCas9	negative selection	9511555
22994624	22994647	8	-	27869803	HPAFII	viability after 27 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.15224215662185436	[395]	[286,184,NaN]	1	hSpCas9	negative selection	9602178
23004605	23004628	8	+	27869803	HPAFII	viability after 27 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.15318280299468462	[353]	[252,95,NaN]	-1	hSpCas9	negative selection	9602179
23005455	23005478	8	-	27869803	HPAFII	viability after 27 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.14083367857234966	[217]	[43,194,NaN]	1	hSpCas9	negative selection	9602180
23006135	23006158	8	-	27869803	HPAFII	viability after 27 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.3833286395515059	[82]	[31,3,NaN]	-7	hSpCas9	negative selection	9602181
23006902	23006925	8	-	27869803	HPAFII	viability after 27 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.5942398562526483	[253]	[88,87,NaN]	-4	hSpCas9	negative selection	9602182
23008101	23008124	8	-	27869803	HPAFII	viability after 27 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.5189577946602879	[135]	[222,1,NaN]	4	hSpCas9	negative selection	9602183
22994624	22994647	8	-	27869803	HPAFII	viability after 15 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.5001829164192131	[395]	[1011,346,NaN]	6	hSpCas9	negative selection	9684627
23004605	23004628	8	+	27869803	HPAFII	viability after 15 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.32234338432844445	[353]	[701,334,NaN]	4	hSpCas9	negative selection	9684628
23005455	23005478	8	-	27869803	HPAFII	viability after 15 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.24257028604339229	[217]	[181,207,NaN]	-3	hSpCas9	negative selection	9684629
23006135	23006158	8	-	27869803	HPAFII	viability after 15 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.08088189637807508	[82]	[145,45,NaN]	-1	hSpCas9	negative selection	9684630
23006902	23006925	8	-	27869803	HPAFII	viability after 15 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.39318768101259177	[253]	[316,139,NaN]	-4	hSpCas9	negative selection	9684631
23008101	23008124	8	-	27869803	HPAFII	viability after 15 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.13122360153898283	[135]	[312,64,NaN]	1	hSpCas9	negative selection	9684632
22994624	22994647	8	-	27869803	ASPC1	viability after 36 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.10598334944758969	[917]	[210,397,392]	1	hSpCas9	negative selection	9767076
23004605	23004628	8	+	27869803	ASPC1	viability after 36 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.9190333070842773	[1033]	[293,1228,513]	8	hSpCas9	negative selection	9767077
23005455	23005478	8	-	27869803	ASPC1	viability after 36 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.38460593798048165	[504]	[158,240,268]	4	hSpCas9	negative selection	9767078
23006135	23006158	8	-	27869803	ASPC1	viability after 36 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.20723734879717548	[222]	[203,26,2]	-2	hSpCas9	negative selection	9767079
23006902	23006925	8	-	27869803	ASPC1	viability after 36 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	0.5043403910893867	[436]	[228,450,18]	5	hSpCas9	negative selection	9767080
23008101	23008124	8	-	27869803	ASPC1	viability after 36 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-1.0215225448124161	[326]	[94,52,30]	-7	hSpCas9	negative selection	9767081
22994624	22994647	8	-	27869803	PATU8988S	viability after 35 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.11796254492056268	[793]	[359,333,NaN]	1	hSpCas9	negative selection	9849525
23004605	23004628	8	+	27869803	PATU8988S	viability after 35 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.21736699685158334	[974]	[471,440,NaN]	2	hSpCas9	negative selection	9849526
23005455	23005478	8	-	27869803	PATU8988S	viability after 35 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.613594341361791	[314]	[243,143,NaN]	6	hSpCas9	negative selection	9849527
23006135	23006158	8	-	27869803	PATU8988S	viability after 35 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	0.4787320442714418	[228]	[138,117,NaN]	5	hSpCas9	negative selection	9849528
23006902	23006925	8	-	27869803	PATU8988S	viability after 35 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.4720355253979919	[366]	[133,78,NaN]	-5	hSpCas9	negative selection	9849529
23008101	23008124	8	-	27869803	PATU8988S	viability after 35 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-1.8196893274613695	[555]	[34,91,NaN]	-8	hSpCas9	negative selection	9849530
22994624	22994647	8	-	27869803	PATU8988S	viability after 31 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.2628109705676962	[793]	[301,478,NaN]	3	hSpCas9	negative selection	9931974
23004605	23004628	8	+	27869803	PATU8988S	viability after 31 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.1836747562372668	[974]	[441,440,NaN]	2	hSpCas9	negative selection	9931975
23005455	23005478	8	-	27869803	PATU8988S	viability after 31 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.786954907135887	[314]	[221,209,NaN]	8	hSpCas9	negative selection	9931976
23006135	23006158	8	-	27869803	PATU8988S	viability after 31 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	0.5623331886151266	[228]	[118,154,NaN]	6	hSpCas9	negative selection	9931977
23006902	23006925	8	-	27869803	PATU8988S	viability after 31 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.49546860856491726	[366]	[116,86,NaN]	-5	hSpCas9	negative selection	9931978
23008101	23008124	8	-	27869803	PATU8988S	viability after 31 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	-2.686654433999184	[555]	[11,62,NaN]	-9	hSpCas9	negative selection	9931979
22994624	22994647	8	-	27869803	HPAFII	viability after 35 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.15038064443989285	[395]	[277,159,NaN]	0	hSpCas9	negative selection	10014423
23004605	23004628	8	+	27869803	HPAFII	viability after 35 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	-0.04864912188019488	[353]	[240,96,NaN]	0	hSpCas9	negative selection	10014424
23005455	23005478	8	-	27869803	HPAFII	viability after 35 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.8025838945688201	[217]	[19,111,NaN]	-5	hSpCas9	negative selection	10014425
23006135	23006158	8	-	27869803	HPAFII	viability after 35 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-1.2710181492367838	[82]	[15,18,NaN]	-6	hSpCas9	negative selection	10014426
23006902	23006925	8	-	27869803	HPAFII	viability after 35 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.39374948474161015	[253]	[79,117,NaN]	-2	hSpCas9	negative selection	10014427
23008101	23008124	8	-	27869803	HPAFII	viability after 35 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.482732956033782	[135]	[162,20,NaN]	3	hSpCas9	negative selection	10014428
22994624	22994647	8	-	27869803	HPAFII	viability after 31 days	TACTCACATGCTGTCTGAAGAGG	RHOBTB2	ENSG00000008853	0.3332975965406144	[395]	[346,206,NaN]	2	hSpCas9	negative selection	10096872
23004605	23004628	8	+	27869803	HPAFII	viability after 31 days	CCAATATCGTGTGTGCCAGGAGG	RHOBTB2	ENSG00000008853	0.3562748648684052	[353]	[361,136,NaN]	2	hSpCas9	negative selection	10096873
23005455	23005478	8	-	27869803	HPAFII	viability after 31 days	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.08547504987070495	[217]	[43,192,NaN]	0	hSpCas9	negative selection	10096874
23006135	23006158	8	-	27869803	HPAFII	viability after 31 days	AGCACCTCCTACCTAGCCAAGGG	RHOBTB2	ENSG00000008853	-0.6095800559568223	[82]	[19,41,NaN]	-4	hSpCas9	negative selection	10096875
23006902	23006925	8	-	27869803	HPAFII	viability after 31 days	GCCGCTGCACATTGCGGAGGTGG	RHOBTB2	ENSG00000008853	-0.6325358175723329	[253]	[34,153,NaN]	-4	hSpCas9	negative selection	10096876
23008101	23008124	8	-	27869803	HPAFII	viability after 31 days	CCTCAGCCTTACCTCCCGGGTGG	RHOBTB2	ENSG00000008853	0.4452577164570974	[135]	[157,44,NaN]	3	hSpCas9	negative selection	10096877
23006905	23006928	8	-	28162770	P31FUJ	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.023625402582094668	[281]	[325]	0	hSpCas9	negative selection	10225084
23006092	23006115	8	+	28162770	P31FUJ	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.8520866931721344	[65]	[139]	8	hSpCas9	negative selection	10225085
23004505	23004528	8	-	28162770	P31FUJ	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.2331722600896904	[479]	[662]	2	hSpCas9	negative selection	10225086
23004532	23004555	8	-	28162770	P31FUJ	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.7998427971382727	[79]	[53]	-6	hSpCas9	negative selection	10225087
23005422	23005445	8	-	28162770	P31FUJ	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.7526982258905062	[99]	[197]	8	hSpCas9	negative selection	10225088
23007016	23007039	8	-	28162770	P31FUJ	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.30776617694832403	[186]	[271]	3	hSpCas9	negative selection	10225089
23007102	23007125	8	-	28162770	P31FUJ	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	1.7827946506366399	[22]	[92]	9	hSpCas9	negative selection	10225090
23008037	23008060	8	-	28162770	P31FUJ	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.10473572692995173	[238]	[301]	1	hSpCas9	negative selection	10225091
23004473	23004496	8	+	28162770	P31FUJ	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.40733054343270036	[418]	[652]	4	hSpCas9	negative selection	10225092
23005455	23005478	8	-	28162770	P31FUJ	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.9129219381758749	[140]	[87]	-6	hSpCas9	negative selection	10225093
23006905	23006928	8	-	28162770	TF1	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10394450
23006092	23006115	8	+	28162770	TF1	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10394451
23004505	23004528	8	-	28162770	TF1	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[516]	1	hSpCas9	negative selection	10394452
23004532	23004555	8	-	28162770	TF1	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10394453
23005422	23005445	8	-	28162770	TF1	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10394454
23007016	23007039	8	-	28162770	TF1	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10394455
23007102	23007125	8	-	28162770	TF1	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10394456
23008037	23008060	8	-	28162770	TF1	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10394457
23004473	23004496	8	+	28162770	TF1	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[426]	1	hSpCas9	negative selection	10394458
23005455	23005478	8	-	28162770	TF1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10394459
23006905	23006928	8	-	28162770	SKM1	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.6463158838468802	[102]	[284]	6	hSpCas9	negative selection	10563816
23006092	23006115	8	+	28162770	SKM1	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.4510167963844105	[11]	[57]	9	hSpCas9	negative selection	10563817
23004505	23004528	8	-	28162770	SKM1	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.09184165822827994	[137]	[259]	0	hSpCas9	negative selection	10563818
23004532	23004555	8	-	28162770	SKM1	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.42953706897395905	[20]	[49]	4	hSpCas9	negative selection	10563819
23005422	23005445	8	-	28162770	SKM1	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10563820
23007016	23007039	8	-	28162770	SKM1	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.0908876382079562	[63]	[240]	8	hSpCas9	negative selection	10563821
23007102	23007125	8	-	28162770	SKM1	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	1.5565099252317243	[4]	[25]	9	hSpCas9	negative selection	10563822
23008037	23008060	8	-	28162770	SKM1	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.3019870192534479	[38]	[84]	3	hSpCas9	negative selection	10563823
23004473	23004496	8	+	28162770	SKM1	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.8892772524805512	[101]	[333]	8	hSpCas9	negative selection	10563824
23005455	23005478	8	-	28162770	SKM1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	1.5994620704162712	[27]	[149]	9	hSpCas9	negative selection	10563825
23006905	23006928	8	-	28162770	SKM1	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.6463158838468802	[102]	[284]	6	hSpCas9	negative selection	10733182
23006092	23006115	8	+	28162770	SKM1	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.4510167963844105	[11]	[57]	9	hSpCas9	negative selection	10733183
23004505	23004528	8	-	28162770	SKM1	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.09184165822827994	[137]	[259]	0	hSpCas9	negative selection	10733184
23004532	23004555	8	-	28162770	SKM1	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.42953706897395905	[20]	[49]	4	hSpCas9	negative selection	10733185
23005422	23005445	8	-	28162770	SKM1	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.27485984123058343	[35]	[76]	2	hSpCas9	negative selection	10733186
23007016	23007039	8	-	28162770	SKM1	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.0908876382079562	[63]	[240]	8	hSpCas9	negative selection	10733187
23007102	23007125	8	-	28162770	SKM1	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	1.5565099252317243	[4]	[25]	9	hSpCas9	negative selection	10733188
23008037	23008060	8	-	28162770	SKM1	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.3019870192534479	[38]	[84]	3	hSpCas9	negative selection	10733189
23004473	23004496	8	+	28162770	SKM1	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.8892772524805512	[101]	[333]	8	hSpCas9	negative selection	10733190
23005455	23005478	8	-	28162770	SKM1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	1.5994620704162712	[27]	[149]	9	hSpCas9	negative selection	10733191
23006905	23006928	8	-	28162770	PL21	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.7489792165084959	[389]	[100]	-5	hSpCas9	negative selection	10902548
23006092	23006115	8	+	28162770	PL21	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	-4.085262604372929	[38]	[0]	-9	hSpCas9	negative selection	10902549
23004505	23004528	8	-	28162770	PL21	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.39932245592695115	[499]	[164]	-3	hSpCas9	negative selection	10902550
23004532	23004555	8	-	28162770	PL21	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.5739544510416511	[70]	[45]	5	hSpCas9	negative selection	10902551
23005422	23005445	8	-	28162770	PL21	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.1873155741317365	[112]	[55]	1	hSpCas9	negative selection	10902552
23007016	23007039	8	-	28162770	PL21	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.3865527387202015	[173]	[98]	3	hSpCas9	negative selection	10902553
23007102	23007125	8	-	28162770	PL21	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.30705481840583193	[25]	[13]	2	hSpCas9	negative selection	10902554
23008037	23008060	8	-	28162770	PL21	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	-0.07486743301054966	[120]	[49]	0	hSpCas9	negative selection	10902555
23004473	23004496	8	+	28162770	PL21	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	-0.16875934661022385	[358]	[138]	-1	hSpCas9	negative selection	10902556
23005455	23005478	8	-	28162770	PL21	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.8917828749517189	[80]	[18]	-6	hSpCas9	negative selection	10902557
23006905	23006928	8	-	28162770	P31FUJ	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.023625402582094668	[281]	[325]	0	hSpCas9	negative selection	11071914
23006092	23006115	8	+	28162770	P31FUJ	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.8520866931721344	[65]	[139]	8	hSpCas9	negative selection	11071915
23004505	23004528	8	-	28162770	P31FUJ	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.2331722600896904	[479]	[662]	2	hSpCas9	negative selection	11071916
23004532	23004555	8	-	28162770	P31FUJ	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.7998427971382727	[79]	[53]	-6	hSpCas9	negative selection	11071917
23005422	23005445	8	-	28162770	P31FUJ	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.7526982258905062	[99]	[197]	8	hSpCas9	negative selection	11071918
23007016	23007039	8	-	28162770	P31FUJ	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.30776617694832403	[186]	[271]	3	hSpCas9	negative selection	11071919
23007102	23007125	8	-	28162770	P31FUJ	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	1.7827946506366399	[22]	[92]	9	hSpCas9	negative selection	11071920
23008037	23008060	8	-	28162770	P31FUJ	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.10473572692995173	[238]	[301]	1	hSpCas9	negative selection	11071921
23004473	23004496	8	+	28162770	P31FUJ	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.40733054343270036	[418]	[652]	4	hSpCas9	negative selection	11071922
23005455	23005478	8	-	28162770	P31FUJ	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.9129219381758749	[140]	[87]	-6	hSpCas9	negative selection	11071923
23006905	23006928	8	-	28162770	OCIAML5	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.5490800396300949	[183]	[226]	-4	hSpCas9	negative selection	11241280
23006092	23006115	8	+	28162770	OCIAML5	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	0.5767767279398772	[38]	[104]	5	hSpCas9	negative selection	11241281
23004505	23004528	8	-	28162770	OCIAML5	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.034028974371434706	[190]	[352]	0	hSpCas9	negative selection	11241282
23004532	23004555	8	-	28162770	OCIAML5	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.17139240195999195	[60]	[123]	1	hSpCas9	negative selection	11241283
23005422	23005445	8	-	28162770	OCIAML5	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	-0.9467034450020723	[62]	[58]	-5	hSpCas9	negative selection	11241284
23007016	23007039	8	-	28162770	OCIAML5	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.09670810578083	[85]	[331]	8	hSpCas9	negative selection	11241285
23007102	23007125	8	-	28162770	OCIAML5	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-0.23908969397324453	[16]	[25]	-2	hSpCas9	negative selection	11241286
23008037	23008060	8	-	28162770	OCIAML5	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	-1.224035348250955	[109]	[84]	-6	hSpCas9	negative selection	11241287
23004473	23004496	8	+	28162770	OCIAML5	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.15751947796520094	[224]	[452]	1	hSpCas9	negative selection	11241288
23005455	23005478	8	-	28162770	OCIAML5	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.48433478636350974	[92]	[119]	-3	hSpCas9	negative selection	11241289
23006905	23006928	8	-	28162770	EOL1	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.15105630137921433	[599]	[350]	1	hSpCas9	negative selection	11410646
23006092	23006115	8	+	28162770	EOL1	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	-0.9685370245129534	[51]	[13]	-6	hSpCas9	negative selection	11410647
23004505	23004528	8	-	28162770	EOL1	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.8128842527558591	[912]	[844]	7	hSpCas9	negative selection	11410648
23004532	23004555	8	-	28162770	EOL1	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.3713940090800546	[156]	[106]	3	hSpCas9	negative selection	11410649
23005422	23005445	8	-	28162770	EOL1	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	-0.06262818807188203	[223]	[112]	0	hSpCas9	negative selection	11410650
23007016	23007039	8	-	28162770	EOL1	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.8251716087766945	[322]	[602]	9	hSpCas9	negative selection	11410651
23007102	23007125	8	-	28162770	EOL1	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	1.740123200433107	[49]	[87]	9	hSpCas9	negative selection	11410652
23008037	23008060	8	-	28162770	EOL1	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.8793185175775369	[161]	[156]	7	hSpCas9	negative selection	11410653
23004473	23004496	8	+	28162770	EOL1	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.8436935190856952	[421]	[398]	7	hSpCas9	negative selection	11410654
23005455	23005478	8	-	28162770	EOL1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.12199481436649551	[125]	[60]	-1	hSpCas9	negative selection	11410655
23006905	23006928	8	-	28162770	MOLM13	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-1.5321106184554214	[511]	[127]	-6	hSpCas9	negative selection	11580012
23006092	23006115	8	+	28162770	MOLM13	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.2048549757107851	[44]	[74]	8	hSpCas9	negative selection	11580013
23004505	23004528	8	-	28162770	MOLM13	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.4105728057374223	[602]	[327]	-2	hSpCas9	negative selection	11580014
23004532	23004555	8	-	28162770	MOLM13	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.9334731808371883	[139]	[52]	-5	hSpCas9	negative selection	11580015
23005422	23005445	8	-	28162770	MOLM13	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.8455907295504499	[136]	[177]	6	hSpCas9	negative selection	11580016
23007016	23007039	8	-	28162770	MOLM13	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	1.0745469533650542	[307]	[468]	7	hSpCas9	negative selection	11580017
23007102	23007125	8	-	28162770	MOLM13	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-0.01753744562566295	[27]	[19]	0	hSpCas9	negative selection	11580018
23008037	23008060	8	-	28162770	MOLM13	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.05710135526709281	[225]	[169]	0	hSpCas9	negative selection	11580019
23004473	23004496	8	+	28162770	MOLM13	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	-0.09185312918730038	[481]	[326]	0	hSpCas9	negative selection	11580020
23005455	23005478	8	-	28162770	MOLM13	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.5744214233133855	[172]	[41]	-7	hSpCas9	negative selection	11580021
23006905	23006928	8	-	28162770	HEL	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.8525565605661818	[427]	[494]	7	hSpCas9	negative selection	11749378
23006092	23006115	8	+	28162770	HEL	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.3742499960744552	[52]	[87]	9	hSpCas9	negative selection	11749379
23004505	23004528	8	-	28162770	HEL	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	0.6282876757028166	[601]	[595]	5	hSpCas9	negative selection	11749380
23004532	23004555	8	-	28162770	HEL	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.48654418494460927	[104]	[47]	-3	hSpCas9	negative selection	11749381
23005422	23005445	8	-	28162770	HEL	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	-0.35726116799964314	[153]	[76]	-3	hSpCas9	negative selection	11749382
23007016	23007039	8	-	28162770	HEL	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.8994107356106116	[302]	[361]	7	hSpCas9	negative selection	11749383
23007102	23007125	8	-	28162770	HEL	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.8651312533368047	[29]	[34]	7	hSpCas9	negative selection	11749384
23008037	23008060	8	-	28162770	HEL	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	0.7383164919825879	[145]	[155]	6	hSpCas9	negative selection	11749385
23004473	23004496	8	+	28162770	HEL	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.9674929709664828	[407]	[510]	8	hSpCas9	negative selection	11749386
23005455	23005478	8	-	28162770	HEL	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.6373690871923785	[135]	[55]	-4	hSpCas9	negative selection	11749387
23006905	23006928	8	-	28162770	MV411	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.7692411903638552	[347]	[171]	-5	hSpCas9	negative selection	11918744
23006092	23006115	8	+	28162770	MV411	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.321438132226552	[37]	[79]	9	hSpCas9	negative selection	11918745
23004505	23004528	8	-	28162770	MV411	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.2908317144903392	[455]	[313]	-2	hSpCas9	negative selection	11918746
23004532	23004555	8	-	28162770	MV411	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	0.08568648078616303	[65]	[58]	0	hSpCas9	negative selection	11918747
23005422	23005445	8	-	28162770	MV411	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	-0.5789143617321949	[171]	[96]	-4	hSpCas9	negative selection	11918748
23007016	23007039	8	-	28162770	MV411	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	-0.009418280121894218	[232]	[194]	0	hSpCas9	negative selection	11918749
23007102	23007125	8	-	28162770	MV411	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.8951358068518942	[29]	[46]	7	hSpCas9	negative selection	11918750
23008037	23008060	8	-	28162770	MV411	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	-0.6270315671333657	[131]	[71]	-4	hSpCas9	negative selection	11918751
23004473	23004496	8	+	28162770	MV411	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.4553073563615222	[270]	[312]	4	hSpCas9	negative selection	11918752
23005455	23005478	8	-	28162770	MV411	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-1.3375249499383808	[92]	[30]	-7	hSpCas9	negative selection	11918753
23006905	23006928	8	-	28162770	MONOMAC1	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.31561144884571235	[224]	[320]	3	hSpCas9	negative selection	12088110
23006092	23006115	8	+	28162770	MONOMAC1	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	-1.1445694271654183	[26]	[13]	-7	hSpCas9	negative selection	12088111
23004505	23004528	8	-	28162770	MONOMAC1	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	1.0426584326869326	[295]	[698]	8	hSpCas9	negative selection	12088112
23004532	23004555	8	-	28162770	MONOMAC1	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.04503375361450357	[44]	[49]	0	hSpCas9	negative selection	12088113
23005422	23005445	8	-	28162770	MONOMAC1	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	1.7069362651666704	[65]	[246]	9	hSpCas9	negative selection	12088114
23007016	23007039	8	-	28162770	MONOMAC1	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	-0.31661846281222605	[175]	[161]	-3	hSpCas9	negative selection	12088115
23007102	23007125	8	-	28162770	MONOMAC1	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.2180006522192901	[29]	[39]	2	hSpCas9	negative selection	12088116
23008037	23008060	8	-	28162770	MONOMAC1	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	-0.6178799680196032	[82]	[61]	-5	hSpCas9	negative selection	12088117
23004473	23004496	8	+	28162770	MONOMAC1	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	-1.061573429764435	[192]	[105]	-7	hSpCas9	negative selection	12088118
23005455	23005478	8	-	28162770	MONOMAC1	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.633038151498134	[53]	[95]	6	hSpCas9	negative selection	12088119
23006905	23006928	8	-	28162770	OCIAML2	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	-0.6226329186872114	[64]	[233]	-5	hSpCas9	negative selection	12257476
23006092	23006115	8	+	28162770	OCIAML2	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	-0.43500591551143986	[9]	[40]	-3	hSpCas9	negative selection	12257477
23004505	23004528	8	-	28162770	OCIAML2	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	-0.014565057703262552	[77]	[427]	0	hSpCas9	negative selection	12257478
23004532	23004555	8	-	28162770	OCIAML2	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	-0.13182791179040287	[16]	[85]	-1	hSpCas9	negative selection	12257479
23005422	23005445	8	-	28162770	OCIAML2	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	0.8054945800320765	[15]	[154]	7	hSpCas9	negative selection	12257480
23007016	23007039	8	-	28162770	OCIAML2	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.7077074160163512	[37]	[343]	7	hSpCas9	negative selection	12257481
23007102	23007125	8	-	28162770	OCIAML2	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	0.31072988828249826	[7]	[54]	3	hSpCas9	negative selection	12257482
23008037	23008060	8	-	28162770	OCIAML2	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	1.7133703614118738	[16]	[308]	9	hSpCas9	negative selection	12257483
23004473	23004496	8	+	28162770	OCIAML2	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	0.175971741271381	[41]	[262]	1	hSpCas9	negative selection	12257484
23005455	23005478	8	-	28162770	OCIAML2	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	0.2174261684430987	[8]	[57]	2	hSpCas9	negative selection	12257485
23006905	23006928	8	-	28162770	OCIAML3	viability	GAGGCCGCTGCACATTGCGGAGG	RHOBTB2	ENSG00000008853	0.39549998585819446	[68]	[273]	3	hSpCas9	negative selection	12426842
23006092	23006115	8	+	28162770	OCIAML3	viability	CCTGCGCTACGCTGACCTGGAGG	RHOBTB2	ENSG00000008853	1.2388823738405785	[15]	[113]	8	hSpCas9	negative selection	12426843
23004505	23004528	8	-	28162770	OCIAML3	viability	GATGAGCCTGGTCTTACCCACGG	RHOBTB2	ENSG00000008853	2.0281534783512427	[133]	[1649]	9	hSpCas9	negative selection	12426844
23004532	23004555	8	-	28162770	OCIAML3	viability	GAGGGTGGCATTGCAAGCGCGGG	RHOBTB2	ENSG00000008853	2.0148016023513606	[19]	[243]	9	hSpCas9	negative selection	12426845
23005422	23005445	8	-	28162770	OCIAML3	viability	GGTCTCCAAAGGTGTCCCAGAGG	RHOBTB2	ENSG00000008853	1.2309056531177458	[34]	[247]	8	hSpCas9	negative selection	12426846
23007016	23007039	8	-	28162770	OCIAML3	viability	AGAGCGGGTCCTCCAGGAGGTGG	RHOBTB2	ENSG00000008853	0.9697071266929538	[56]	[336]	8	hSpCas9	negative selection	12426847
23007102	23007125	8	-	28162770	OCIAML3	viability	ATAGAACTTGGAGGAAGAGGTGG	RHOBTB2	ENSG00000008853	-0.7126521368227821	[18]	[34]	-5	hSpCas9	negative selection	12426848
23008037	23008060	8	-	28162770	OCIAML3	viability	TCACAGCTGGAAATCAACAGGGG	RHOBTB2	ENSG00000008853	1.8893838772573155	[37]	[424]	9	hSpCas9	negative selection	12426849
23004473	23004496	8	+	28162770	OCIAML3	viability	GACCATCAAGTGCGTTGTGGTGG	RHOBTB2	ENSG00000008853	1.6522315229666527	[89]	[853]	9	hSpCas9	negative selection	12426850
23005455	23005478	8	-	28162770	OCIAML3	viability	ACCTCCCATAAGCAAAGCGACGG	RHOBTB2	ENSG00000008853	-0.22722530965254029	[37]	[97]	-2	hSpCas9	negative selection	12426851