Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 89941
• Symbol: RHOT2
• Description: ras homolog family member T2

DataSource: http://genomecrispr.dkfz.de/#!/results/RHOT2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
668387	668410	16	+	26472758	Jiyoye	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	0.3300075209834134	[95]	[90]	2	hSpCas9	negative selection	136882
672951	672974	16	-	26472758	Jiyoye	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.11301686382504483	[293]	[204]	-1	hSpCas9	negative selection	136883
668491	668514	16	-	26472758	Jiyoye	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	3.0186100935882205	[8]	[54]	9	hSpCas9	negative selection	136884
668666	668689	16	+	26472758	Jiyoye	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	1.9921378822270295	[12]	[38]	8	hSpCas9	negative selection	136885
670285	670308	16	+	26472758	Jiyoye	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.3741843320187863	[54]	[15]	-7	hSpCas9	negative selection	136886
670347	670370	16	-	26472758	Jiyoye	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	0.0433632055822028	[165]	[128]	0	hSpCas9	negative selection	136887
670945	670968	16	+	26472758	Jiyoye	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.9265620156711223	[367]	[145]	-6	hSpCas9	negative selection	136888
671131	671154	16	-	26472758	Jiyoye	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.07315357802468958	[225]	[161]	0	hSpCas9	negative selection	136889
672147	672170	16	-	26472758	Jiyoye	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.78922183129763	[164]	[71]	-5	hSpCas9	negative selection	136890
672510	672533	16	-	26472758	Jiyoye	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.2750843205701977	[206]	[128]	-2	hSpCas9	negative selection	136891
668387	668410	16	+	26472758	KBM7	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.5152920868771962	[572,275]	[73,61]	-8	hSpCas9	negative selection	328000
672951	672974	16	-	26472758	KBM7	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.13430358710900547	[1033,656]	[398,316]	-1	hSpCas9	negative selection	328001
668491	668514	16	-	26472758	KBM7	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.5959887290458616	[268,118]	[43,70]	-5	hSpCas9	negative selection	328002
668666	668689	16	+	26472758	KBM7	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-0.9644080634795908	[289,196]	[32,79]	-6	hSpCas9	negative selection	328003
670285	670308	16	+	26472758	KBM7	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.8186758677820825	[234,147]	[23,25]	-8	hSpCas9	negative selection	328004
670347	670370	16	-	26472758	KBM7	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.9415492641477161	[723,585]	[56,99]	-8	hSpCas9	negative selection	328005
670945	670968	16	+	26472758	KBM7	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.2921807949719437	[1339,1271]	[566,444]	-3	hSpCas9	negative selection	328006
671131	671154	16	-	26472758	KBM7	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.6450358356113132	[803,789]	[751,441]	7	hSpCas9	negative selection	328007
672147	672170	16	-	26472758	KBM7	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.7229438406990799	[344,288]	[62,113]	-6	hSpCas9	negative selection	328008
672510	672533	16	-	26472758	KBM7	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.09360269170602792	[614,569]	[390,213]	0	hSpCas9	negative selection	328009
668387	668410	16	+	26472758	Raji	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.2849338874051607	[230]	[43]	-2	hSpCas9	negative selection	519118
672951	672974	16	-	26472758	Raji	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-1.006358630675589	[553]	[63]	-6	hSpCas9	negative selection	519119
668491	668514	16	-	26472758	Raji	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.36545168831404373	[96]	[28]	3	hSpCas9	negative selection	519120
668666	668689	16	+	26472758	Raji	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-0.2525124097127833	[153]	[29]	-2	hSpCas9	negative selection	519121
670285	670308	16	+	26472758	Raji	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.7752595139882414	[117]	[3]	-9	hSpCas9	negative selection	519122
670347	670370	16	-	26472758	Raji	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	0.7288719121198697	[181]	[69]	6	hSpCas9	negative selection	519123
670945	670968	16	+	26472758	Raji	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.017498031856404417	[595]	[139]	0	hSpCas9	negative selection	519124
671131	671154	16	-	26472758	Raji	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.12265029202691002	[375]	[94]	1	hSpCas9	negative selection	519125
672147	672170	16	-	26472758	Raji	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.3454754293402116	[218]	[39]	-3	hSpCas9	negative selection	519126
672510	672533	16	-	26472758	Raji	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.06997805491049436	[388]	[85]	0	hSpCas9	negative selection	519127
668387	668410	16	+	26472758	K562	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.9705941633044033	[324]	[69]	-7	hSpCas9	negative selection	710236
672951	672974	16	-	26472758	K562	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	0.20996467133732077	[677]	[661]	1	hSpCas9	negative selection	710237
668491	668514	16	-	26472758	K562	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.1974976802789543	[124]	[120]	1	hSpCas9	negative selection	710238
668666	668689	16	+	26472758	K562	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-1.9255062737758655	[224]	[49]	-7	hSpCas9	negative selection	710239
670285	670308	16	+	26472758	K562	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.045087889528538	[219]	[44]	-7	hSpCas9	negative selection	710240
670347	670370	16	-	26472758	K562	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.9239788040292716	[471]	[209]	-5	hSpCas9	negative selection	710241
670945	670968	16	+	26472758	K562	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.5608805848661536	[1051]	[601]	-4	hSpCas9	negative selection	710242
671131	671154	16	-	26472758	K562	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.4223004529371023	[662]	[749]	3	hSpCas9	negative selection	710243
672147	672170	16	-	26472758	K562	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.8644177643764597	[288]	[66]	-7	hSpCas9	negative selection	710244
672510	672533	16	-	26472758	K562	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.3441839287082422	[418]	[448]	2	hSpCas9	negative selection	710245
668215	668238	16	+	26627737	DLD1	viability	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-1.793954064700862	[613]	[93,59,17]	-8	hSpCas9	negative selection	795283
669540	669563	16	+	26627737	DLD1	viability	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-1.376367425537051	[799]	[69,81,130]	-8	hSpCas9	negative selection	795290
670245	670268	16	-	26627737	DLD1	viability	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-1.6891506445744584	[968]	[36,115,124]	-8	hSpCas9	negative selection	795292
670452	670475	16	-	26627737	DLD1	viability	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.6429845917436696	[558]	[119,118,98]	-6	hSpCas9	negative selection	795294
670737	670760	16	-	26627737	DLD1	viability	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	1.4447975204656467	[68]	[66,33,71]	9	hSpCas9	negative selection	795300
671101	671124	16	+	26627737	DLD1	viability	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.6931253322738886	[14]	[17,0,3]	7	hSpCas9	negative selection	795302
668215	668238	16	+	26627737	GBM cells	viability after 5 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.823330213573755	[324]	[99,96]	-8	hSpCas9	negative selection	877598
669540	669563	16	+	26627737	GBM cells	viability after 5 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.13814728559944678	[437]	[245,270]	2	hSpCas9	negative selection	877605
670245	670268	16	-	26627737	GBM cells	viability after 5 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.9497345083300929	[442]	[126,118]	-9	hSpCas9	negative selection	877607
670452	670475	16	-	26627737	GBM cells	viability after 5 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.16612001053180425	[362]	[187,158]	-3	hSpCas9	negative selection	877609
670737	670760	16	-	26627737	GBM cells	viability after 5 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	0.1583005037043348	[65]	[46,31]	2	hSpCas9	negative selection	877615
671101	671124	16	+	26627737	GBM cells	viability after 5 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.8285245469942879	[20]	[20,18]	9	hSpCas9	negative selection	877617
668215	668238	16	+	26627737	GBM cells	viability after 13 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.40308694984692295	[324]	[150,118]	-5	hSpCas9	negative selection	959913
669540	669563	16	+	26627737	GBM cells	viability after 13 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.09197432760713409	[437]	[233,213]	-1	hSpCas9	negative selection	959920
670245	670268	16	-	26627737	GBM cells	viability after 13 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.4943123587769444	[442]	[195,149]	-5	hSpCas9	negative selection	959922
670452	670475	16	-	26627737	GBM cells	viability after 13 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.06765877673452403	[362]	[276,148]	0	hSpCas9	negative selection	959924
670737	670760	16	-	26627737	GBM cells	viability after 13 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	0.25158578103105156	[65]	[67,21]	3	hSpCas9	negative selection	959930
671101	671124	16	+	26627737	GBM cells	viability after 13 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.734359407910999	[20]	[70,10]	9	hSpCas9	negative selection	959932
668215	668238	16	+	26627737	GBM cells	viability after 21 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.2954740544206601	[324]	[146,140]	-3	hSpCas9	negative selection	1042228
669540	669563	16	+	26627737	GBM cells	viability after 21 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.29927272945199823	[437]	[308,277]	3	hSpCas9	negative selection	1042235
670245	670268	16	-	26627737	GBM cells	viability after 21 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-1.0952972366795581	[442]	[120,104]	-7	hSpCas9	negative selection	1042237
670452	670475	16	-	26627737	GBM cells	viability after 21 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.2158213337126943	[362]	[239,218]	2	hSpCas9	negative selection	1042239
670737	670760	16	-	26627737	GBM cells	viability after 21 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.027568375935288714	[65]	[30,38]	0	hSpCas9	negative selection	1042245
671101	671124	16	+	26627737	GBM cells	viability after 21 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-0.5120841231631017	[20]	[7,7]	-4	hSpCas9	negative selection	1042247
668215	668238	16	+	26627737	RPE1	viability after 9 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.6836851659822228	[1064]	[276,117]	-5	hSpCas9	negative selection	1124543
669540	669563	16	+	26627737	RPE1	viability after 9 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.3487372669454334	[1852]	[417,503]	-2	hSpCas9	negative selection	1124550
670245	670268	16	-	26627737	RPE1	viability after 9 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.456867443406448	[1152]	[377,646]	3	hSpCas9	negative selection	1124552
670452	670475	16	-	26627737	RPE1	viability after 9 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.2925549705879892	[1155]	[389,511]	2	hSpCas9	negative selection	1124554
670737	670760	16	-	26627737	RPE1	viability after 9 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-1.204427506729013	[284]	[22,58]	-7	hSpCas9	negative selection	1124560
671101	671124	16	+	26627737	RPE1	viability after 9 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.3795287626672423	[59]	[16,89]	7	hSpCas9	negative selection	1124562
668215	668238	16	+	26627737	RPE1	viability after 12 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	0.006963527320803853	[1064]	[338,232]	0	hSpCas9	negative selection	1206858
669540	669563	16	+	26627737	RPE1	viability after 12 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-1.0068361019734173	[1852]	[289,202]	-6	hSpCas9	negative selection	1206865
670245	670268	16	-	26627737	RPE1	viability after 12 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.5604436877921123	[1152]	[314,606]	3	hSpCas9	negative selection	1206867
670452	670475	16	-	26627737	RPE1	viability after 12 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.0798683233706291	[1155]	[319,336]	0	hSpCas9	negative selection	1206869
670737	670760	16	-	26627737	RPE1	viability after 12 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	0.08266915973661892	[284]	[100,59]	0	hSpCas9	negative selection	1206875
671101	671124	16	+	26627737	RPE1	viability after 12 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.525273716304829	[59]	[25,67]	8	hSpCas9	negative selection	1206877
668215	668238	16	+	26627737	RPE1	viability after 15 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.7731964384209113	[1064]	[216,136]	-5	hSpCas9	negative selection	1289173
669540	669563	16	+	26627737	RPE1	viability after 15 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.7973753715571483	[1852]	[379,225]	-5	hSpCas9	negative selection	1289180
670245	670268	16	-	26627737	RPE1	viability after 15 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.1953529783681145	[1152]	[347,397]	1	hSpCas9	negative selection	1289182
670452	670475	16	-	26627737	RPE1	viability after 15 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.4438537806966082	[1155]	[511,379]	3	hSpCas9	negative selection	1289184
670737	670760	16	-	26627737	RPE1	viability after 15 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.10887107842007193	[284]	[31,115]	0	hSpCas9	negative selection	1289190
671101	671124	16	+	26627737	RPE1	viability after 15 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.476651614530351	[59]	[16,29]	3	hSpCas9	negative selection	1289192
668215	668238	16	+	26627737	RPE1	viability after 18 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.14697038380374355	[1064]	[319,194]	-1	hSpCas9	negative selection	1371488
669540	669563	16	+	26627737	RPE1	viability after 18 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.7967188065788864	[1852]	[385,182]	-5	hSpCas9	negative selection	1371495
670245	670268	16	-	26627737	RPE1	viability after 18 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.4251143210950661	[1152]	[396,439]	2	hSpCas9	negative selection	1371497
670452	670475	16	-	26627737	RPE1	viability after 18 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.316363762249553	[1155]	[328,451]	2	hSpCas9	negative selection	1371499
670737	670760	16	-	26627737	RPE1	viability after 18 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.5960800814583631	[284]	[61,38]	-4	hSpCas9	negative selection	1371505
671101	671124	16	+	26627737	RPE1	viability after 18 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.8191421773828629	[59]	[15,41]	5	hSpCas9	negative selection	1371507
668215	668238	16	+	26627737	HeLa	viability after 8 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	0.22444357487591093	[366]	[163,192,196]	2	hSpCas9	negative selection	1453803
669540	669563	16	+	26627737	HeLa	viability after 8 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.14443074903559766	[563]	[352,194,151]	-1	hSpCas9	negative selection	1453810
670245	670268	16	-	26627737	HeLa	viability after 8 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	1.0166957748919998	[309]	[214,302,286]	7	hSpCas9	negative selection	1453812
670452	670475	16	-	26627737	HeLa	viability after 8 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.197900851281132	[637]	[508,269,224]	2	hSpCas9	negative selection	1453814
670737	670760	16	-	26627737	HeLa	viability after 8 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	2.0592749740802176	[55]	[118,109,80]	9	hSpCas9	negative selection	1453820
671101	671124	16	+	26627737	HeLa	viability after 8 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.827341246253245	[14]	[49,25,0]	9	hSpCas9	negative selection	1453822
668215	668238	16	+	26627737	HeLa	viability after 12 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	0.19815323085370634	[366]	[108,174,235]	1	hSpCas9	negative selection	1536118
669540	669563	16	+	26627737	HeLa	viability after 12 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.25011565535484803	[563]	[219,135,238]	-2	hSpCas9	negative selection	1536125
670245	670268	16	-	26627737	HeLa	viability after 12 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.6691166200861398	[309]	[80,142,389]	5	hSpCas9	negative selection	1536127
670452	670475	16	-	26627737	HeLa	viability after 12 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-1.0095084490257482	[637]	[63,205,112]	-7	hSpCas9	negative selection	1536129
670737	670760	16	-	26627737	HeLa	viability after 12 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	1.2899354744381502	[55]	[49,61,56]	8	hSpCas9	negative selection	1536135
671101	671124	16	+	26627737	HeLa	viability after 12 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.937754915760753	[14]	[17,9,7]	7	hSpCas9	negative selection	1536137
668215	668238	16	+	26627737	HeLa	viability after 15 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.2895892282313899	[366]	[40,116,216]	-2	hSpCas9	negative selection	1618433
669540	669563	16	+	26627737	HeLa	viability after 15 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.17585361344729122	[563]	[372,139,263]	1	hSpCas9	negative selection	1618440
670245	670268	16	-	26627737	HeLa	viability after 15 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	1.4468257613597038	[309]	[416,247,367]	8	hSpCas9	negative selection	1618442
670452	670475	16	-	26627737	HeLa	viability after 15 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.7352567806317672	[637]	[108,235,120]	-6	hSpCas9	negative selection	1618444
670737	670760	16	-	26627737	HeLa	viability after 15 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	1.3304815282712417	[55]	[53,24,95]	8	hSpCas9	negative selection	1618450
671101	671124	16	+	26627737	HeLa	viability after 15 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.8190670382515735	[14]	[31,4,27]	9	hSpCas9	negative selection	1618452
668215	668238	16	+	26627737	HeLa	viability after 18 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.3079872292209669	[366]	[25,94,216]	-3	hSpCas9	negative selection	1700748
669540	669563	16	+	26627737	HeLa	viability after 18 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.17066900862610657	[563]	[245,118,263]	1	hSpCas9	negative selection	1700755
670245	670268	16	-	26627737	HeLa	viability after 18 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	1.4253808245017734	[309]	[266,208,367]	8	hSpCas9	negative selection	1700757
670452	670475	16	-	26627737	HeLa	viability after 18 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.7082567225222087	[637]	[75,198,120]	-6	hSpCas9	negative selection	1700759
670737	670760	16	-	26627737	HeLa	viability after 18 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	1.3713861530190343	[55]	[39,19,95]	8	hSpCas9	negative selection	1700765
671101	671124	16	+	26627737	HeLa	viability after 18 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.8670337507476455	[14]	[22,3,27]	9	hSpCas9	negative selection	1700767
668215	668238	16	+	26627737	HCT116	viability after 6 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.10609893534872228	[987]	[162,133]	0	hSpCas9	negative selection	1783063
669540	669563	16	+	26627737	HCT116	viability after 6 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.6834792545839989	[2289]	[325,167]	-4	hSpCas9	negative selection	1783070
670245	670268	16	-	26627737	HCT116	viability after 6 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.9022520160781606	[1545]	[334,519]	5	hSpCas9	negative selection	1783072
670452	670475	16	-	26627737	HCT116	viability after 6 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.587721776546251	[813]	[152,213]	3	hSpCas9	negative selection	1783074
670737	670760	16	-	26627737	HCT116	viability after 6 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.062486175719126624	[203]	[31,29]	0	hSpCas9	negative selection	1783080
671101	671124	16	+	26627737	HCT116	viability after 6 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	2.3032674121620698	[35]	[25,28]	9	hSpCas9	negative selection	1783082
668215	668238	16	+	26627737	HCT116	viability after 8 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	1.0602401286447247	[172]	[207,146,240]	8	hSpCas9	negative selection	1865378
669540	669563	16	+	26627737	HCT116	viability after 8 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.20176950405071958	[467]	[251,259,375]	2	hSpCas9	negative selection	1865385
670245	670268	16	-	26627737	HCT116	viability after 8 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.3921089647840405	[542]	[173,277,230]	-4	hSpCas9	negative selection	1865387
670452	670475	16	-	26627737	HCT116	viability after 8 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.45918456910571204	[600]	[276,261,184]	-5	hSpCas9	negative selection	1865389
670737	670760	16	-	26627737	HCT116	viability after 8 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	2.2782734674798313	[24]	[63,116,19]	9	hSpCas9	negative selection	1865395
671101	671124	16	+	26627737	HCT116	viability after 8 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-0.7171153753912409	[23]	[5,1,15]	-7	hSpCas9	negative selection	1865397
668215	668238	16	+	26627737	HCT116	viability after 9 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	0.19511339104693592	[987]	[277,320]	1	hSpCas9	negative selection	1947693
669540	669563	16	+	26627737	HCT116	viability after 9 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-1.037060783689239	[2289]	[383,229]	-6	hSpCas9	negative selection	1947700
670245	670268	16	-	26627737	HCT116	viability after 9 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.6299537888565685	[1545]	[249,279]	-4	hSpCas9	negative selection	1947702
670452	670475	16	-	26627737	HCT116	viability after 9 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.35527964441046733	[813]	[310,251]	2	hSpCas9	negative selection	1947704
670737	670760	16	-	26627737	HCT116	viability after 9 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	1.6079953311355342	[203]	[322,41]	8	hSpCas9	negative selection	1947710
671101	671124	16	+	26627737	HCT116	viability after 9 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-0.9692386367746613	[35]	[0,7]	-6	hSpCas9	negative selection	1947712
668215	668238	16	+	26627737	HCT116	viability after 12 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	1.4655152069275221	[172]	[362,110,265]	9	hSpCas9	negative selection	2030008
669540	669563	16	+	26627737	HCT116	viability after 12 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.27341205028426707	[467]	[212,288,396]	3	hSpCas9	negative selection	2030015
670245	670268	16	-	26627737	HCT116	viability after 12 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.5443760250215467	[542]	[210,250,124]	-5	hSpCas9	negative selection	2030017
670452	670475	16	-	26627737	HCT116	viability after 12 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.6564362522272227	[600]	[221,189,186]	-6	hSpCas9	negative selection	2030019
670737	670760	16	-	26627737	HCT116	viability after 12 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	2.4569463842353425	[24]	[72,140,3]	9	hSpCas9	negative selection	2030025
671101	671124	16	+	26627737	HCT116	viability after 12 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-0.8623348063626088	[23]	[3,3,12]	-7	hSpCas9	negative selection	2030027
668215	668238	16	+	26627737	HCT116	viability after 15 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	1.1914082995829312	[172]	[217,266,194]	8	hSpCas9	negative selection	2112323
669540	669563	16	+	26627737	HCT116	viability after 15 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.03959850185677172	[467]	[302,180,304]	0	hSpCas9	negative selection	2112330
670245	670268	16	-	26627737	HCT116	viability after 15 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.19782500972254013	[542]	[293,223,299]	-2	hSpCas9	negative selection	2112332
670452	670475	16	-	26627737	HCT116	viability after 15 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.7021349138669197	[600]	[204,252,177]	-6	hSpCas9	negative selection	2112334
670737	670760	16	-	26627737	HCT116	viability after 15 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	2.3808794397167152	[24]	[125,64,39]	9	hSpCas9	negative selection	2112340
671101	671124	16	+	26627737	HCT116	viability after 15 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-0.6021218823945351	[23]	[7,0,17]	-6	hSpCas9	negative selection	2112342
668215	668238	16	+	26627737	HCT116	viability after 18 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	1.4602001762960384	[172]	[307,149,237]	9	hSpCas9	negative selection	2194638
669540	669563	16	+	26627737	HCT116	viability after 18 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.17886580299818972	[467]	[131,155,319]	-2	hSpCas9	negative selection	2194645
670245	670268	16	-	26627737	HCT116	viability after 18 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.3894603828784713	[542]	[248,130,226]	-4	hSpCas9	negative selection	2194647
670452	670475	16	-	26627737	HCT116	viability after 18 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.6618018027607073	[600]	[192,170,187]	-6	hSpCas9	negative selection	2194649
670737	670760	16	-	26627737	HCT116	viability after 18 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	2.0207779556772385	[24]	[73,39,32]	9	hSpCas9	negative selection	2194655
671101	671124	16	+	26627737	HCT116	viability after 18 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	-1.812731160893549	[23]	[6,0,1]	-8	hSpCas9	negative selection	2194657
671098	671121	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	0.04126026932055507	[3,3]	[4,2]	0	hSpCas9	positive selection	3016806
668503	668526	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	-0.38581313777902554	[2,2]	[0,1]	-5	hSpCas9	positive selection	3016807
668496	668519	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	-0.01091079427385229	[3,3]	[3,1]	0	hSpCas9	positive selection	3016808
668388	668411	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.2978259692907081	[3,3]	[1,0]	-9	hSpCas9	positive selection	3016809
671098	671121	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	0.2963394195672635	[3,3]	[2,3]	5	hSpCas9	positive selection	3084664
668503	668526	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	-0.2737729480935509	[2,2]	[0,0]	-4	hSpCas9	positive selection	3084665
668496	668519	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	0.09470198857109426	[3,3]	[2,1]	1	hSpCas9	positive selection	3084666
668388	668411	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.653065128845979	[3,3]	[2,0]	-8	hSpCas9	positive selection	3084667
671144	671167		-	24336571	A375	resistance to PLX after 7 days	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.3152863774039634	[8,8]	[9,12]	8	hSpCas9	positive selection	3140897
671171	671194		-	24336571	A375	resistance to PLX after 7 days	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	-0.3087229475570147	[11,14]	[9,11]	-8	hSpCas9	positive selection	3140898
671963	671986		-	24336571	A375	resistance to PLX after 7 days	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.4379533916388033	[9,9]	[6,6]	-9	hSpCas9	positive selection	3140900
671978	672001		+	24336571	A375	resistance to PLX after 7 days	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	0.07301560919417649	[7,8]	[9,8]	2	hSpCas9	positive selection	3140901
671144	671167		-	24336571	A375	resistance to PLX after 14 days	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.9764262364916306	[8,6]	[7,6]	7	hSpCas9	positive selection	3198690
671171	671194		-	24336571	A375	resistance to PLX after 14 days	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	-0.7280182902582666	[19,10]	[3,3]	-8	hSpCas9	positive selection	3198691
671963	671986		-	24336571	A375	resistance to PLX after 14 days	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-1.181008366384845	[12,12]	[2,1]	-9	hSpCas9	positive selection	3198693
671978	672001		+	24336571	A375	resistance to PLX after 14 days	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	0.2591380407392847	[6,5]	[3,2]	2	hSpCas9	positive selection	3198694
671144	671167		-	24336571	A375	viability after 7 days	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.13963231208296673	[10]	[8,8]	-2	hSpCas9	negative selection	3256483
671171	671194		-	24336571	A375	viability after 7 days	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	0.11332629518457696	[12]	[11,14]	1	hSpCas9	negative selection	3256484
671963	671986		-	24336571	A375	viability after 7 days	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.09984936139514394	[9]	[9,9]	1	hSpCas9	negative selection	3256486
671978	672001		+	24336571	A375	viability after 7 days	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	-0.5061496205931322	[12]	[7,8]	-6	hSpCas9	negative selection	3256487
671144	671167		-	24336571	A375	viability after 14 days	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.2986111634826727	[10]	[8,6]	-4	hSpCas9	negative selection	3314276
671171	671194		-	24336571	A375	viability after 14 days	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	0.3376010053974676	[12]	[19,10]	4	hSpCas9	negative selection	3314277
671963	671986		-	24336571	A375	viability after 14 days	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.47527725430999773	[9]	[12,12]	6	hSpCas9	negative selection	3314279
671978	672001		+	24336571	A375	viability after 14 days	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	-0.9150029751920441	[12]	[6,5]	-8	hSpCas9	negative selection	3314280
671865	671888	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.11777485904704146	[140,140]	[0,0]	0	hSpCas9	positive selection	3389814
672084	672107	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	1.801542369823682	[394,394]	[8,8]	7	hSpCas9	positive selection	3389815
672114	672137	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3389816
671097	671120	16	+	26780180	HT29	viability (Avana library 4 designs)	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	0.779100739421708	[]	[]	3	hSpCas9	negative selection	3455152
668502	668525	16	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	2.08349457259132	[]	[]	7	hSpCas9	negative selection	3455153
668496	668519	16	-	26780180	HT29	viability (Avana library 4 designs)	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	1.41916179189755	[]	[]	5	hSpCas9	negative selection	3455154
668387	668410	16	+	26780180	HT29	viability (Avana library 4 designs)	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	2.30564366257886	[]	[]	8	hSpCas9	negative selection	3455155
668502	668525	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	2.64375703286512	[]	[]	4	hSpCas9	negative selection	3552993
668496	668519	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	-0.506527942144424	[]	[]	0	hSpCas9	negative selection	3552994
668387	668410	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	5.0113093775303	[]	[]	8	hSpCas9	negative selection	3552995
671097	671120	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	2.4914559041439	[]	[]	3	hSpCas9	negative selection	3552996
668678	668701	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGGGAGGAGATCCACAAGG	RHOT2	ENSG00000140983	3.00100792812316	[]	[]	4	hSpCas9	negative selection	3552997
668481	668504	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGCAGGTCCCTCCCCGCGCGG	RHOT2	ENSG00000140983	4.01723395025817	[]	[]	6	hSpCas9	negative selection	3552998
668502	668525	16	+	26780180	A375	viability (Avana lentiGuide)	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	0.924565637303366	[]	[]	1	hSpCas9	negative selection	3661652
668496	668519	16	-	26780180	A375	viability (Avana lentiGuide)	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	2.31108438029573	[]	[]	2	hSpCas9	negative selection	3661653
668387	668410	16	+	26780180	A375	viability (Avana lentiGuide)	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	15.5322024648143	[]	[]	8	hSpCas9	negative selection	3661654
671097	671120	16	+	26780180	A375	viability (Avana lentiGuide)	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	5.40144669771483	[]	[]	5	hSpCas9	negative selection	3661655
668678	668701	16	+	26780180	A375	viability (Avana lentiGuide)	GCTGCGGGAGGAGATCCACAAGG	RHOT2	ENSG00000140983	16.798039553323	[]	[]	8	hSpCas9	negative selection	3661656
668481	668504	16	+	26780180	A375	viability (Avana lentiGuide)	CTTGCAGGTCCCTCCCCGCGCGG	RHOT2	ENSG00000140983	3.49099758596521	[]	[]	3	hSpCas9	negative selection	3661657
668502	668525	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	-0.05308430143901227	[3]	[3,3]	-1	hSpCas9	positive selection	3770259
668496	668519	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	-0.22050862963418644	[4]	[6,1]	-3	hSpCas9	positive selection	3770260
668387	668410	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	0.24406368429059205	[4]	[6,4]	7	hSpCas9	positive selection	3770261
671097	671120	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	0.13232124015235908	[5]	[6,5]	3	hSpCas9	positive selection	3770262
668678	668701	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGGGAGGAGATCCACAAGG	RHOT2	ENSG00000140983	0.01135684843079754	[4]	[4,3]	0	hSpCas9	positive selection	3770263
668481	668504	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGCAGGTCCCTCCCCGCGCGG	RHOT2	ENSG00000140983	0.15225066727435246	[3]	[4,4]	4	hSpCas9	positive selection	3770264
668502	668525	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGAGATCACCATCCCCGCGG	RHOT2	ENSG00000140983	-0.15681021730797082	[4]	[3,2]	-2	hSpCas9	positive selection	3878866
668496	668519	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGGTGATCTCCTCCGCGCGG	RHOT2	ENSG00000140983	-0.4564929812857897	[5]	[4,1]	-5	hSpCas9	positive selection	3878867
668387	668410	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	0.09501801367848707	[5]	[3,5]	2	hSpCas9	positive selection	3878868
671097	671120	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACACGCTCTTCATCCAGCGCGG	RHOT2	ENSG00000140983	-0.030172986683807967	[5]	[5,3]	0	hSpCas9	positive selection	3878869
668678	668701	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGGGAGGAGATCCACAAGG	RHOT2	ENSG00000140983	-0.5355437821653433	[4]	[1,2]	-6	hSpCas9	positive selection	3878870
668481	668504	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGCAGGTCCCTCCCCGCGCGG	RHOT2	ENSG00000140983	-0.5370968308660512	[4]	[2,2]	-6	hSpCas9	positive selection	3878871
672114	672137	16	-	26780180	A375	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.923331215274521	[]	[]	4	hSpCas9	negative selection	3988998
671865	671888	16	+	26780180	A375	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	1.04381063236533	[]	[]	5	hSpCas9	negative selection	3988999
671144	671167	16	-	26780180	A375	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	1.44418024024605	[]	[]	8	hSpCas9	negative selection	3989000
671153	671176	16	+	26780180	A375	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	1.71819090163367	[]	[]	9	hSpCas9	negative selection	3989001
672084	672107	16	-	26780180	A375	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	1.52995290377312	[]	[]	8	hSpCas9	negative selection	3989002
671963	671986	16	-	26780180	A375	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	1.39438994812322	[]	[]	7	hSpCas9	negative selection	3989003
672114	672137	16	-	26780180	HT29	viability (GeCKOv2 library)	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	1.26603803816523	[]	[]	6	hSpCas9	negative selection	4096964
671865	671888	16	+	26780180	HT29	viability (GeCKOv2 library)	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	1.46090785344033	[]	[]	7	hSpCas9	negative selection	4096965
671144	671167	16	-	26780180	HT29	viability (GeCKOv2 library)	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	1.44955680707456	[]	[]	7	hSpCas9	negative selection	4096966
671153	671176	16	+	26780180	HT29	viability (GeCKOv2 library)	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	1.66893871845555	[]	[]	8	hSpCas9	negative selection	4096967
672084	672107	16	-	26780180	HT29	viability (GeCKOv2 library)	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	1.5043696435789	[]	[]	7	hSpCas9	negative selection	4096968
671963	671986	16	-	26780180	HT29	viability (GeCKOv2 library)	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	1.81171237189552	[]	[]	8	hSpCas9	negative selection	4096969
671144	671167	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.019539798775959318	[3]	[1,2]	0	hSpCas9	positive selection	4166388
671171	671194	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	-0.26930355336461514	[3]	[1,1]	-6	hSpCas9	positive selection	4166389
671963	671986	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.6055158050780596	[3]	[1,0]	-9	hSpCas9	positive selection	4166391
671978	672001	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	0.06353881536647071	[3]	[3,1]	1	hSpCas9	positive selection	4166392
671144	671167	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.42410354192168814	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4230410
671171	671194	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATAGTCCGCAGTCAGCTCCAGG	RHOT2	ENSG00000140983	0.1037967523843858	[1]	[1,0,0,0]	0	hSpCas9	positive selection	4230411
671963	671986	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	1.4617972231284337	[2]	[3,0,4,4]	9	hSpCas9	positive selection	4230413
671978	672001	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCACGGATACCTCTGCCAGTGG	RHOT2	ENSG00000140983	0.32792093019133717	[3]	[3,0,4,0]	2	hSpCas9	positive selection	4230414
671144	671167	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.0675298860317386	[2]	[2,1]	1	hSpCas9	positive selection	4294836
671153	671176	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.0014069843361763645	[3]	[3,2]	0	hSpCas9	positive selection	4294837
671963	671986	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	1.1496752417256806	[2]	[2,7]	9	hSpCas9	positive selection	4294838
671865	671888	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.16292939009929439	[2]	[2,0]	-3	hSpCas9	positive selection	4359090
672084	672107	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	-0.36410660224915564	[3]	[2,1]	-6	hSpCas9	positive selection	4359091
672114	672137	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.43391815663308225	[2]	[3,2]	8	hSpCas9	positive selection	4359092
671154	671176	16	+	27760321	OCIAML3	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.17254168535885983	[952,721]	[503,670]	-2	hSpCas9	negative selection	4434592
668519	668541	16	-	27760321	OCIAML3	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	0.015504987608031734	[489,477]	[333,447]	0	hSpCas9	negative selection	4434593
668555	668577	16	+	27760321	OCIAML3	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.38159018466425265	[432,389]	[295,578]	4	hSpCas9	negative selection	4434594
670272	670294	16	+	27760321	OCIAML3	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.19113000864764668	[698,563]	[355,526]	-2	hSpCas9	negative selection	4434595
670489	670511	16	+	27760321	OCIAML3	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	-0.20774039749009554	[689,667]	[392,548]	-2	hSpCas9	negative selection	4434596
671154	671176	16	+	27760321	OCIAML2	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-1.2998897298755379	[952,721]	[215,347]	-8	hSpCas9	negative selection	4518055
668519	668541	16	-	27760321	OCIAML2	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.6584621259832895	[489,477]	[157,367]	-6	hSpCas9	negative selection	4518056
668555	668577	16	+	27760321	OCIAML2	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	-0.6308386494663908	[432,389]	[165,278]	-6	hSpCas9	negative selection	4518057
670272	670294	16	+	27760321	OCIAML2	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-1.5155319238203648	[698,563]	[137,229]	-8	hSpCas9	negative selection	4518058
670489	670511	16	+	27760321	OCIAML2	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	-0.7768307649198396	[689,667]	[268,389]	-7	hSpCas9	negative selection	4518059
671154	671176	16	+	27760321	MV411	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.34942051329869106	[952,721]	[777,578]	2	hSpCas9	negative selection	4601518
668519	668541	16	-	27760321	MV411	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.11075204908807529	[489,477]	[369,185]	-1	hSpCas9	negative selection	4601519
668555	668577	16	+	27760321	MV411	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.18762658355921527	[432,389]	[252,392]	1	hSpCas9	negative selection	4601520
670272	670294	16	+	27760321	MV411	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.6562081466898582	[698,563]	[238,298]	-4	hSpCas9	negative selection	4601521
670489	670511	16	+	27760321	MV411	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.04796708847579689	[689,667]	[374,597]	0	hSpCas9	negative selection	4601522
671154	671176	16	+	27760321	HL60	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.2138005510570391	[952,721]	[573,596]	-2	hSpCas9	negative selection	4684981
668519	668541	16	-	27760321	HL60	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.45193207940170854	[489,477]	[262,317]	-5	hSpCas9	negative selection	4684982
668555	668577	16	+	27760321	HL60	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.856675980867212	[432,389]	[627,586]	8	hSpCas9	negative selection	4684983
670272	670294	16	+	27760321	HL60	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.4286706873427729	[698,563]	[352,410]	-5	hSpCas9	negative selection	4684984
670489	670511	16	+	27760321	HL60	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.009594348471295144	[689,667]	[590,525]	0	hSpCas9	negative selection	4684985
671154	671176	16	+	27760321	HT1080	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.21557981533920478	[721,563]	[169,436]	1	hSpCas9	negative selection	4768444
668519	668541	16	-	27760321	HT1080	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	0.6803560148428982	[477,372]	[263,279]	3	hSpCas9	negative selection	4768445
668555	668577	16	+	27760321	HT1080	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	-0.32230902266523115	[389,304]	[83,139]	-1	hSpCas9	negative selection	4768446
670272	670294	16	+	27760321	HT1080	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	0.11419682046043339	[563,439]	[246,182]	0	hSpCas9	negative selection	4768447
670489	670511	16	+	27760321	HT1080	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	-2.1771015690245594	[667,520]	[38,66]	-6	hSpCas9	negative selection	4768448
671154	671176	16	+	27760321	HT29	viability after 7 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.17248757552755412	[721,563]	[1141,816,866]	2	hSpCas9	negative selection	4851907
668519	668541	16	-	27760321	HT29	viability after 7 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	0.3012426646759395	[477,372]	[767,474,787]	4	hSpCas9	negative selection	4851908
668555	668577	16	+	27760321	HT29	viability after 7 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.6200645747782702	[389,304]	[885,650,554]	8	hSpCas9	negative selection	4851909
670272	670294	16	+	27760321	HT29	viability after 7 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.0038411107809706024	[563,439]	[728,654,560]	0	hSpCas9	negative selection	4851910
670489	670511	16	+	27760321	HT29	viability after 7 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.20955578758824933	[667,520]	[625,1090,895]	3	hSpCas9	negative selection	4851911
671154	671176	16	+	27760321	HT29	viability after 25 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.4824041999964006	[721,563]	[1110,1022,928]	5	hSpCas9	negative selection	4935370
668519	668541	16	-	27760321	HT29	viability after 25 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.1284694927747223	[477,372]	[525,389,408]	-1	hSpCas9	negative selection	4935371
668555	668577	16	+	27760321	HT29	viability after 25 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.30881809876115845	[389,304]	[470,543,457]	3	hSpCas9	negative selection	4935372
670272	670294	16	+	27760321	HT29	viability after 25 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	0.1251217670075218	[563,439]	[539,503,861]	1	hSpCas9	negative selection	4935373
670489	670511	16	+	27760321	HT29	viability after 25 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	-0.13536978346166328	[667,520]	[593,610,654]	-1	hSpCas9	negative selection	4935374
671154	671176	16	+	27760321	HT29	viability after 22 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.15745368616986266	[721,563]	[821,885,778]	1	hSpCas9	negative selection	5018833
668519	668541	16	-	27760321	HT29	viability after 22 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.274204935579761	[477,372]	[371,355,493]	-3	hSpCas9	negative selection	5018834
668555	668577	16	+	27760321	HT29	viability after 22 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.22222512862957128	[389,304]	[504,541,356]	2	hSpCas9	negative selection	5018835
670272	670294	16	+	27760321	HT29	viability after 22 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.18141428314123165	[563,439]	[442,486,607]	-2	hSpCas9	negative selection	5018836
670489	670511	16	+	27760321	HT29	viability after 22 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.3796498477557	[667,520]	[801,864,1018]	4	hSpCas9	negative selection	5018837
671154	671176	16	+	27760321	HT29	viability after 19 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.3619862611483402	[721,563]	[853,749,1210]	3	hSpCas9	negative selection	5102296
668519	668541	16	-	27760321	HT29	viability after 19 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	0.04041032394990507	[477,372]	[697,518,311]	0	hSpCas9	negative selection	5102297
668555	668577	16	+	27760321	HT29	viability after 19 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.8493860357987313	[389,304]	[754,706,690]	8	hSpCas9	negative selection	5102298
670272	670294	16	+	27760321	HT29	viability after 19 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.06282791879446864	[563,439]	[693,401,566]	0	hSpCas9	negative selection	5102299
670489	670511	16	+	27760321	HT29	viability after 19 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.39004080601683344	[667,520]	[765,756,1126]	4	hSpCas9	negative selection	5102300
671154	671176	16	+	27760321	HT29	viability after 16 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.35901504780021964	[721,563]	[1054,978,744]	4	hSpCas9	negative selection	5185759
668519	668541	16	-	27760321	HT29	viability after 16 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.017210443253788704	[477,372]	[778,327,336]	0	hSpCas9	negative selection	5185760
668555	668577	16	+	27760321	HT29	viability after 16 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.5120774607046645	[389,304]	[697,669,305]	6	hSpCas9	negative selection	5185761
670272	670294	16	+	27760321	HT29	viability after 16 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.0419024524122541	[563,439]	[638,521,484]	0	hSpCas9	negative selection	5185762
670489	670511	16	+	27760321	HT29	viability after 16 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.20400001213100383	[667,520]	[795,806,696]	2	hSpCas9	negative selection	5185763
671154	671176	16	+	27760321	HT29	viability after 13 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.32719512723451527	[721,563]	[769,1256,789]	4	hSpCas9	negative selection	5269222
668519	668541	16	-	27760321	HT29	viability after 13 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	-0.012106280861567453	[477,372]	[557,501,412]	0	hSpCas9	negative selection	5269223
668555	668577	16	+	27760321	HT29	viability after 13 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.25757577484497735	[389,304]	[525,338,574]	3	hSpCas9	negative selection	5269224
670272	670294	16	+	27760321	HT29	viability after 13 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	-0.05817442911433618	[563,439]	[355,653,661]	0	hSpCas9	negative selection	5269225
670489	670511	16	+	27760321	HT29	viability after 13 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.06701298387067645	[667,520]	[760,732,675]	0	hSpCas9	negative selection	5269226
671154	671176	16	+	27760321	HT29	viability after 10 days	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.20665891883779208	[721,563]	[1249,853,678]	2	hSpCas9	negative selection	5352685
668519	668541	16	-	27760321	HT29	viability after 10 days	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	0.07000791322197636	[477,372]	[646,358,658]	0	hSpCas9	negative selection	5352686
668555	668577	16	+	27760321	HT29	viability after 10 days	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.3492272769051285	[389,304]	[678,551,429]	5	hSpCas9	negative selection	5352687
670272	670294	16	+	27760321	HT29	viability after 10 days	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	0.057620559145767636	[563,439]	[747,713,499]	0	hSpCas9	negative selection	5352688
670489	670511	16	+	27760321	HT29	viability after 10 days	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	-0.06798800417133755	[667,520]	[803,482,827]	-1	hSpCas9	negative selection	5352689
671154	671176	16	+	27760321	MOLM13	viability	TTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.17505888623594845	[952,721]	[445,599]	1	hSpCas9	negative selection	5436148
668519	668541	16	-	27760321	MOLM13	viability	TTCTCCGGGGTGACGTCCGCGG	RHOT2	ENSG00000140983	1.34425433882194	[489,477]	[1119,332]	8	hSpCas9	negative selection	5436149
668555	668577	16	+	27760321	MOLM13	viability	TCGTGGACTACTCAGGTAGCGG	RHOT2	ENSG00000140983	0.7080554626340336	[432,389]	[292,451]	5	hSpCas9	negative selection	5436150
670272	670294	16	+	27760321	MOLM13	viability	ACAAGTCAGACCTGCGGTCGGG	RHOT2	ENSG00000140983	0.6744476738694242	[698,563]	[867,307]	4	hSpCas9	negative selection	5436151
670489	670511	16	+	27760321	MOLM13	viability	CTGTTCTACTACGCCCAGAAGG	RHOT2	ENSG00000140983	0.10075869760663059	[689,667]	[537,303]	0	hSpCas9	negative selection	5436152
668183	668206	16	+	27661255	K562	viability	GGCTCCGGGCGGCAGCTATGAGG	RHOT2	ENSG00000140983	0.1804516412991241	[581,709]	[640,532]	6	dCas9-KRAB	negative selection	5507385
668531	668554	16	-	27661255	K562	viability	GTGGGTGGGCACCTTCTCCGGGG	RHOT2	ENSG00000140983	0.15434797308553883	[2167,2366]	[2159,1886]	5	dCas9-KRAB	negative selection	5507386
668545	668568	16	-	27661255	K562	viability	GAGTAGTCCACGATGTGGGTGGG	RHOT2	ENSG00000140983	0.05383599472936146	[1008,1050]	[955,765]	1	dCas9-KRAB	negative selection	5507387
668628	668651	16	-	27661255	K562	viability	GGGACAAAGAGACTCCACTGCGG	RHOT2	ENSG00000140983	-0.2003247316686359	[1226,1173]	[925,757]	-6	dCas9-KRAB	negative selection	5507388
671144	671167	16	-	27260156	BXPC3	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.20020868713919504	[304]	[271,264,278,295]	-4	hSpCas9	negative selection	5567296
671153	671176	16	+	27260156	BXPC3	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.08705963886046975	[853]	[791,899,973,1168]	2	hSpCas9	negative selection	5567297
671963	671986	16	-	27260156	BXPC3	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.24860991032401353	[351]	[435,345,370,619]	5	hSpCas9	negative selection	5567298
671865	671888	16	+	27260156	BXPC3	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.13188760432231855	[352]	[382,347,403,496]	3	hSpCas9	negative selection	5631550
672084	672107	16	-	27260156	BXPC3	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5524738976697084	[578]	[708,856,899,1130]	9	hSpCas9	negative selection	5631551
672114	672137	16	-	27260156	BXPC3	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.16880131053137748	[412]	[372,294,409,473]	-4	hSpCas9	negative selection	5631552
671144	671167	16	-	27260156	A673	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.11941605372043473	[304]	[391,233,383,346]	-3	hSpCas9	negative selection	5688547
671153	671176	16	+	27260156	A673	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.12659205388489747	[853]	[1084,879,887,919]	-3	hSpCas9	negative selection	5688548
671963	671986	16	-	27260156	A673	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.1775003365888181	[351]	[418,316,415,346]	-4	hSpCas9	negative selection	5688549
671865	671888	16	+	27260156	A673	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.12407489715890685	[352]	[520,440,494,392]	3	hSpCas9	negative selection	5752801
672084	672107	16	-	27260156	A673	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5954001441736768	[578]	[1140,1040,961,1067]	9	hSpCas9	negative selection	5752802
672114	672137	16	-	27260156	A673	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.08925532573523126	[412]	[606,586,453,465]	2	hSpCas9	negative selection	5752803
671144	671167	16	-	27260156	A375	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.09080450622652181	[304]	[353,373,368,254]	-1	hSpCas9	negative selection	5809798
671153	671176	16	+	27260156	A375	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.30283208850046994	[853]	[663,751,966,835]	-4	hSpCas9	negative selection	5809799
671963	671986	16	-	27260156	A375	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.11320941226746489	[351]	[390,319,431,368]	-2	hSpCas9	negative selection	5809800
671865	671888	16	+	27260156	A375	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.679676422842677	[352]	[281,211,275,252]	-7	hSpCas9	negative selection	5874052
672084	672107	16	-	27260156	A375	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.4685540677523169	[578]	[1044,839,897,942]	7	hSpCas9	negative selection	5874053
672114	672137	16	-	27260156	A375	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.5008583096472471	[412]	[383,367,288,326]	-6	hSpCas9	negative selection	5874054
671144	671167	16	-	27260156	COLO741	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.07540686443925271	[304]	[425,367,322]	-2	hSpCas9	negative selection	5931049
671153	671176	16	+	27260156	COLO741	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.037042162012441926	[853]	[1324,968,1081]	0	hSpCas9	negative selection	5931050
671963	671986	16	-	27260156	COLO741	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.2839924461765051	[351]	[603,560,485]	6	hSpCas9	negative selection	5931051
671865	671888	16	+	27260156	COLO741	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.14540812956659044	[352]	[522,524,452]	3	hSpCas9	negative selection	5995303
672084	672107	16	-	27260156	COLO741	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6397799324181731	[578]	[1026,1306,1113]	9	hSpCas9	negative selection	5995304
672114	672137	16	-	27260156	COLO741	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.005457103846695954	[412]	[648,519,435]	0	hSpCas9	negative selection	5995305
671144	671167	16	-	27260156	CAL120	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.21320193012842475	[304]	[337,446,517]	3	hSpCas9	negative selection	6052300
671153	671176	16	+	27260156	CAL120	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.3163991119725943	[853]	[964,717,892]	-4	hSpCas9	negative selection	6052301
671963	671986	16	-	27260156	CAL120	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.09003815977224289	[351]	[721,364,197]	-1	hSpCas9	negative selection	6052302
671865	671888	16	+	27260156	CAL120	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.055192673070982856	[352]	[696,351,357]	0	hSpCas9	negative selection	6116554
672084	672107	16	-	27260156	CAL120	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.4565222112930566	[578]	[966,1151,845]	6	hSpCas9	negative selection	6116555
672114	672137	16	-	27260156	CAL120	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.051074400650988006	[412]	[654,451,508]	0	hSpCas9	negative selection	6116556
671144	671167	16	-	27260156	CADOES1	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.1626940157612921	[304]	[220,312,299,440]	3	hSpCas9	negative selection	6173551
671153	671176	16	+	27260156	CADOES1	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.3235141044675559	[853]	[584,842,564,542]	-5	hSpCas9	negative selection	6173552
671963	671986	16	-	27260156	CADOES1	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.348763462075607	[351]	[277,183,234,333]	-6	hSpCas9	negative selection	6173553
671865	671888	16	+	27260156	CADOES1	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.3470040238850975	[352]	[236,296,281,214]	-6	hSpCas9	negative selection	6237805
672084	672107	16	-	27260156	CADOES1	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6519993961380468	[578]	[842,943,749,847]	9	hSpCas9	negative selection	6237806
672114	672137	16	-	27260156	CADOES1	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.17323983059542297	[412]	[305,388,270,398]	-3	hSpCas9	negative selection	6237807
671144	671167	16	-	27260156	EWS502	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.0028656481527151723	[304]	[332,283,285,389]	0	hSpCas9	negative selection	6294802
671153	671176	16	+	27260156	EWS502	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.20808739789226982	[853]	[670,850,653,975]	-4	hSpCas9	negative selection	6294803
671963	671986	16	-	27260156	EWS502	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.2919666826605246	[351]	[312,406,580,550]	5	hSpCas9	negative selection	6294804
671865	671888	16	+	27260156	EWS502	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.07808390607445248	[352]	[474,295,383,417]	1	hSpCas9	negative selection	6359056
672084	672107	16	-	27260156	EWS502	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6420818070952816	[578]	[869,626,1121,1252]	9	hSpCas9	negative selection	6359057
672114	672137	16	-	27260156	EWS502	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.030399256630786603	[412]	[325,332,575,580]	0	hSpCas9	negative selection	6359058
671144	671167	16	-	27260156	EW8	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.012902091926300208	[304]	[374,170,191,281]	0	hSpCas9	negative selection	6416053
671153	671176	16	+	27260156	EW8	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.06629759914324862	[853]	[719,690,540,716]	-1	hSpCas9	negative selection	6416054
671963	671986	16	-	27260156	EW8	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.048385994579908886	[351]	[305,253,244,305]	-1	hSpCas9	negative selection	6416055
671865	671888	16	+	27260156	EW8	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.11328101656196377	[352]	[356,332,299,253]	2	hSpCas9	negative selection	6480307
672084	672107	16	-	27260156	EW8	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5500353120218973	[578]	[790,672,540,776]	8	hSpCas9	negative selection	6480308
672114	672137	16	-	27260156	EW8	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.15784639410763623	[412]	[498,237,234,259]	-3	hSpCas9	negative selection	6480309
671144	671167	16	-	27260156	CORL105	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.4074425227834748	[304]	[270,310,261,230]	-6	hSpCas9	negative selection	6537304
671153	671176	16	+	27260156	CORL105	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.15763721299850997	[853]	[1065,727,927,876]	-3	hSpCas9	negative selection	6537305
671963	671986	16	-	27260156	CORL105	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.2758111151018341	[351]	[566,327,500,604]	5	hSpCas9	negative selection	6537306
671865	671888	16	+	27260156	CORL105	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.034274610094817026	[352]	[370,427,519,386]	0	hSpCas9	negative selection	6601558
672084	672107	16	-	27260156	CORL105	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.7462241791649397	[578]	[989,1104,1440,1054]	9	hSpCas9	negative selection	6601559
672114	672137	16	-	27260156	CORL105	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.047915626925154636	[412]	[732,386,475,409]	0	hSpCas9	negative selection	6601560
671144	671167	16	-	27260156	HS294T	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.031198631913996078	[304]	[123,101,139,114]	0	hSpCas9	negative selection	6658555
671153	671176	16	+	27260156	HS294T	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.3945115261523402	[853]	[216,214,287,295]	-5	hSpCas9	negative selection	6658556
671963	671986	16	-	27260156	HS294T	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.1221288383068942	[351]	[108,204,115,166]	1	hSpCas9	negative selection	6658557
671865	671888	16	+	27260156	HS294T	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.09396542852806006	[352]	[92,161,179,152]	1	hSpCas9	negative selection	6722809
672084	672107	16	-	27260156	HS294T	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5713979931381677	[578]	[285,418,258,373]	7	hSpCas9	negative selection	6722810
672114	672137	16	-	27260156	HS294T	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.32590351708829346	[412]	[88,146,109,173]	-4	hSpCas9	negative selection	6722811
671144	671167	16	-	27260156	HCC44	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.13458849096812608	[304]	[273,363,352,260]	-2	hSpCas9	negative selection	6779806
671153	671176	16	+	27260156	HCC44	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.287845231944048	[853]	[1114,834,1405,1424]	5	hSpCas9	negative selection	6779807
671963	671986	16	-	27260156	HCC44	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.3611799613163081	[351]	[646,356,495,570]	6	hSpCas9	negative selection	6779808
671865	671888	16	+	27260156	HCC44	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.34786736742329105	[352]	[620,382,501,547]	5	hSpCas9	negative selection	6844060
672084	672107	16	-	27260156	HCC44	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6764971234162495	[578]	[1159,812,1249,1033]	9	hSpCas9	negative selection	6844061
672114	672137	16	-	27260156	HCC44	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.19829007500471119	[412]	[392,353,804,642]	3	hSpCas9	negative selection	6844062
671144	671167	16	-	27260156	G402	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.23005036669771173	[304]	[390,168,349,357]	-3	hSpCas9	negative selection	6901057
671153	671176	16	+	27260156	G402	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.057348329832231815	[853]	[927,1262,815,1302]	0	hSpCas9	negative selection	6901058
671963	671986	16	-	27260156	G402	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.5258626660194794	[351]	[276,332,281,298]	-6	hSpCas9	negative selection	6901059
671865	671888	16	+	27260156	G402	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.19477762749098965	[352]	[108,419,269,654]	-2	hSpCas9	negative selection	6965311
672084	672107	16	-	27260156	G402	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6354306651751871	[578]	[1056,1230,1138,966]	7	hSpCas9	negative selection	6965312
672114	672137	16	-	27260156	G402	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.11466413592049216	[412]	[960,267,295,691]	1	hSpCas9	negative selection	6965313
671144	671167	16	-	27260156	L33	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.06821742232682737	[304]	[241,141,170,303]	-1	hSpCas9	negative selection	7022308
671153	671176	16	+	27260156	L33	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.27191908590355574	[853]	[686,296,433,726]	-6	hSpCas9	negative selection	7022309
671963	671986	16	-	27260156	L33	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.11861184391604346	[351]	[323,176,193,232]	-3	hSpCas9	negative selection	7022310
671865	671888	16	+	27260156	L33	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.1909939219504632	[352]	[431,167,236,391]	4	hSpCas9	negative selection	7086562
672084	672107	16	-	27260156	L33	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.3646122832266402	[578]	[711,317,488,716]	7	hSpCas9	negative selection	7086563
672114	672137	16	-	27260156	L33	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.06875972441060874	[412]	[351,164,211,482]	-1	hSpCas9	negative selection	7086564
671144	671167	16	-	27260156	K562	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.08809529562649232	[304]	[228,247,273,262]	-1	hSpCas9	negative selection	7143559
671153	671176	16	+	27260156	K562	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.07729540335504514	[853]	[794,1068,670,686]	0	hSpCas9	negative selection	7143560
671963	671986	16	-	27260156	K562	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.46113581441739104	[351]	[256,482,688,293]	6	hSpCas9	negative selection	7143561
671865	671888	16	+	27260156	K562	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.04165873844404616	[352]	[246,464,157,344]	0	hSpCas9	negative selection	7207813
672084	672107	16	-	27260156	K562	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6867239950181061	[578]	[639,1021,1115,553]	8	hSpCas9	negative selection	7207814
672114	672137	16	-	27260156	K562	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.2692510158748944	[412]	[234,231,295,427]	-3	hSpCas9	negative selection	7207815
671144	671167	16	-	27260156	HT29	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.09141638063987145	[304]	[287,344,505,256]	-2	hSpCas9	negative selection	7264810
671153	671176	16	+	27260156	HT29	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.07580116474218013	[853]	[806,1142,1416,995]	1	hSpCas9	negative selection	7264811
671963	671986	16	-	27260156	HT29	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.08669929507462382	[351]	[432,661,321,417]	1	hSpCas9	negative selection	7264812
671865	671888	16	+	27260156	HT29	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.05450299800806402	[352]	[459,454,346,396]	-1	hSpCas9	negative selection	7329064
672084	672107	16	-	27260156	HT29	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6492863919594297	[578]	[1144,1145,1258,890]	9	hSpCas9	negative selection	7329065
672114	672137	16	-	27260156	HT29	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.021044816339575084	[412]	[629,416,596,352]	0	hSpCas9	negative selection	7329066
671144	671167	16	-	27260156	MHHES1	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.059582902637482116	[304]	[584,330,374,195]	1	hSpCas9	negative selection	7386061
671153	671176	16	+	27260156	MHHES1	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.07672929385717697	[853]	[914,844,950,909]	-1	hSpCas9	negative selection	7386062
671963	671986	16	-	27260156	MHHES1	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.008542701448515544	[351]	[390,422,519,281]	0	hSpCas9	negative selection	7386063
671865	671888	16	+	27260156	MHHES1	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.24654284302793908	[352]	[410,560,432,471]	4	hSpCas9	negative selection	7450315
672084	672107	16	-	27260156	MHHES1	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.719881218971382	[578]	[1100,1348,1123,794]	9	hSpCas9	negative selection	7450316
672114	672137	16	-	27260156	MHHES1	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.3017094520316902	[412]	[519,502,239,287]	-5	hSpCas9	negative selection	7450317
671144	671167	16	-	27260156	MEWO	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.04141462889631575	[304]	[219,206,393]	-1	hSpCas9	negative selection	7507312
671153	671176	16	+	27260156	MEWO	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.17419869635404606	[853]	[729,783,613]	-4	hSpCas9	negative selection	7507313
671963	671986	16	-	27260156	MEWO	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.06631128881517889	[351]	[363,357,315]	1	hSpCas9	negative selection	7507314
671865	671888	16	+	27260156	MEWO	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.05535442300487958	[352]	[412,335,293]	1	hSpCas9	negative selection	7571566
672084	672107	16	-	27260156	MEWO	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5086501084503788	[578]	[799,673,843]	8	hSpCas9	negative selection	7571567
672114	672137	16	-	27260156	MEWO	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.26468634516883915	[412]	[465,429,496]	6	hSpCas9	negative selection	7571568
671144	671167	16	-	27260156	LNCAPCLONEFGC	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.2951095211522562	[304]	[344,409,271,313]	4	hSpCas9	negative selection	7628563
671153	671176	16	+	27260156	LNCAPCLONEFGC	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.07373955741977412	[853]	[823,688,987,788]	1	hSpCas9	negative selection	7628564
671963	671986	16	-	27260156	LNCAPCLONEFGC	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.06982977463247858	[351]	[335,276,302,299]	-1	hSpCas9	negative selection	7628565
671865	671888	16	+	27260156	LNCAPCLONEFGC	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.15535074539584842	[352]	[392,426,336,258]	2	hSpCas9	negative selection	7692817
672084	672107	16	-	27260156	LNCAPCLONEFGC	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6133156252324982	[578]	[708,745,920,855]	8	hSpCas9	negative selection	7692818
672114	672137	16	-	27260156	LNCAPCLONEFGC	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.35010084640288835	[412]	[409,419,744,376]	5	hSpCas9	negative selection	7692819
671144	671167	16	-	27260156	PANC0327	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.40362776623790064	[304]	[308,78,226,228]	-5	hSpCas9	negative selection	7749814
671153	671176	16	+	27260156	PANC0327	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.1291350372974155	[853]	[1152,563,682,428]	-2	hSpCas9	negative selection	7749815
671963	671986	16	-	27260156	PANC0327	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.5140351720140774	[351]	[198,128,356,200]	-6	hSpCas9	negative selection	7749816
671865	671888	16	+	27260156	PANC0327	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.260191572681804	[352]	[414,317,494,284]	4	hSpCas9	negative selection	7814068
672084	672107	16	-	27260156	PANC0327	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.7133584185815868	[578]	[1356,638,580,863]	8	hSpCas9	negative selection	7814069
672114	672137	16	-	27260156	PANC0327	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.6068926515384773	[412]	[186,247,186,335]	-7	hSpCas9	negative selection	7814070
671144	671167	16	-	27260156	NCIH2009	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.22404899077667628	[304]	[473,422,591]	3	hSpCas9	negative selection	7871065
671153	671176	16	+	27260156	NCIH2009	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.17430972806083822	[853]	[1286,821,1110]	-2	hSpCas9	negative selection	7871066
671963	671986	16	-	27260156	NCIH2009	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.6965270360137377	[351]	[927,717,770]	8	hSpCas9	negative selection	7871067
671865	671888	16	+	27260156	NCIH2009	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.26547037273079	[352]	[671,600,519]	3	hSpCas9	negative selection	7935319
672084	672107	16	-	27260156	NCIH2009	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.7019801969824865	[578]	[1941,1060,1070]	8	hSpCas9	negative selection	7935320
672114	672137	16	-	27260156	NCIH2009	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.4872153353994329	[412]	[671,813,911]	6	hSpCas9	negative selection	7935321
671144	671167	16	-	27260156	NCIH1373	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.4243249746802429	[304]	[569,343,532,107]	4	hSpCas9	negative selection	7992316
671153	671176	16	+	27260156	NCIH1373	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.21633052124252428	[853]	[864,989,564,227]	-2	hSpCas9	negative selection	7992317
671963	671986	16	-	27260156	NCIH1373	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.024758317612061487	[351]	[487,277,421,101]	0	hSpCas9	negative selection	7992318
671865	671888	16	+	27260156	NCIH1373	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.19281891097242745	[352]	[377,815,328,57]	2	hSpCas9	negative selection	8056570
672084	672107	16	-	27260156	NCIH1373	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.6190868811117095	[578]	[855,1295,841,244]	6	hSpCas9	negative selection	8056571
672114	672137	16	-	27260156	NCIH1373	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.14151415418119379	[412]	[320,589,445,171]	1	hSpCas9	negative selection	8056572
671144	671167	16	-	27260156	PATU8902	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.5827338331042153	[304]	[518,375,503,1248]	6	hSpCas9	negative selection	8113567
671153	671176	16	+	27260156	PATU8902	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.12899548183506604	[853]	[1309,1071,950,1034]	-1	hSpCas9	negative selection	8113568
671963	671986	16	-	27260156	PATU8902	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.45087823793463555	[351]	[636,761,581,723]	5	hSpCas9	negative selection	8113569
671865	671888	16	+	27260156	PATU8902	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.7850252770500913	[352]	[1085,858,262,1386]	8	hSpCas9	negative selection	8177821
672084	672107	16	-	27260156	PATU8902	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.7750626656969942	[578]	[1407,2037,817,1393]	7	hSpCas9	negative selection	8177822
672114	672137	16	-	27260156	PATU8902	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.5026897448339027	[412]	[820,804,818,805]	5	hSpCas9	negative selection	8177823
671144	671167	16	-	27260156	PANC1	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.09792255877160783	[304]	[306,201,279,185]	-2	hSpCas9	negative selection	8234818
671153	671176	16	+	27260156	PANC1	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.061570870349003215	[853]	[747,985,533,603]	-1	hSpCas9	negative selection	8234819
671963	671986	16	-	27260156	PANC1	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.3610869258603331	[351]	[284,456,614,233]	6	hSpCas9	negative selection	8234820
671865	671888	16	+	27260156	PANC1	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.03907455174522745	[352]	[259,289,287,330]	0	hSpCas9	negative selection	8299072
672084	672107	16	-	27260156	PANC1	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.545910275558324	[578]	[616,1001,789,568]	8	hSpCas9	negative selection	8299073
672114	672137	16	-	27260156	PANC1	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.07723114940966386	[412]	[339,432,411,197]	-1	hSpCas9	negative selection	8299074
671144	671167	16	-	27260156	PANC0813	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.2501806616611466	[304]	[581,374,390,372]	4	hSpCas9	negative selection	8356069
671153	671176	16	+	27260156	PANC0813	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.424300467426631	[853]	[665,766,652,886]	-6	hSpCas9	negative selection	8356070
671963	671986	16	-	27260156	PANC0813	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.06642301256893135	[351]	[343,587,418,374]	1	hSpCas9	negative selection	8356071
671865	671888	16	+	27260156	PANC0813	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.19388094913154919	[352]	[564,356,422,554]	3	hSpCas9	negative selection	8420323
672084	672107	16	-	27260156	PANC0813	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5677973100172752	[578]	[785,977,1335,916]	8	hSpCas9	negative selection	8420324
672114	672137	16	-	27260156	PANC0813	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.06087616741039467	[412]	[554,359,572,384]	-1	hSpCas9	negative selection	8420325
671144	671167	16	-	27260156	RDES	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.24652696151596704	[304]	[313,431,457,479]	4	hSpCas9	negative selection	8477320
671153	671176	16	+	27260156	RDES	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.11846966814429671	[853]	[783,1038,1215,1299]	2	hSpCas9	negative selection	8477321
671963	671986	16	-	27260156	RDES	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.2525777307119557	[351]	[395,408,571,581]	4	hSpCas9	negative selection	8477322
671865	671888	16	+	27260156	RDES	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.4167170757793401	[352]	[499,453,521,717]	6	hSpCas9	negative selection	8541574
672084	672107	16	-	27260156	RDES	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.8462817746865677	[578]	[930,1421,1203,1235]	9	hSpCas9	negative selection	8541575
672114	672137	16	-	27260156	RDES	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.42082738952615056	[412]	[473,636,778,681]	6	hSpCas9	negative selection	8541576
671144	671167	16	-	27260156	PC3	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.07643103549251362	[304]	[174,376,391,264]	-2	hSpCas9	negative selection	8598571
671153	671176	16	+	27260156	PC3	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.023598829604752014	[853]	[601,821,1309,809]	0	hSpCas9	negative selection	8598572
671963	671986	16	-	27260156	PC3	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.3612961519549789	[351]	[359,464,626,400]	7	hSpCas9	negative selection	8598573
671865	671888	16	+	27260156	PC3	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.25560633883533224	[352]	[319,293,1004,286]	5	hSpCas9	negative selection	8662825
672084	672107	16	-	27260156	PC3	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5273383175669337	[578]	[557,791,1490,776]	9	hSpCas9	negative selection	8662826
672114	672137	16	-	27260156	PC3	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.25376669285157755	[412]	[332,508,841,429]	5	hSpCas9	negative selection	8662827
671144	671167	16	-	27260156	PATU8988T	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.029277840221502593	[304]	[273,331,239,365]	0	hSpCas9	negative selection	8719822
671153	671176	16	+	27260156	PATU8988T	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.08319697383137592	[853]	[383,827,904,1020]	-1	hSpCas9	negative selection	8719823
671963	671986	16	-	27260156	PATU8988T	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.10274689613847549	[351]	[363,380,167,365]	-2	hSpCas9	negative selection	8719824
671865	671888	16	+	27260156	PATU8988T	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.2055402277829938	[352]	[269,294,338,276]	-3	hSpCas9	negative selection	8784076
672084	672107	16	-	27260156	PATU8988T	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.2038881954797419	[578]	[669,738,484,698]	3	hSpCas9	negative selection	8784077
672114	672137	16	-	27260156	PATU8988T	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.5307285775643681	[412]	[164,302,207,445]	-7	hSpCas9	negative selection	8784078
671144	671167	16	-	27260156	T47D	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.12444077574955481	[304]	[271,275,394,364]	-3	hSpCas9	negative selection	8841073
671153	671176	16	+	27260156	T47D	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.16536315379090116	[853]	[993,902,750,901]	-4	hSpCas9	negative selection	8841074
671963	671986	16	-	27260156	T47D	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.1867604052414286	[351]	[477,454,546,383]	4	hSpCas9	negative selection	8841075
671865	671888	16	+	27260156	T47D	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.200942852847409	[352]	[442,395,470,590]	4	hSpCas9	negative selection	8905327
672084	672107	16	-	27260156	T47D	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.49545131678876897	[578]	[1033,819,1053,903]	9	hSpCas9	negative selection	8905328
672114	672137	16	-	27260156	T47D	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.11362844428339078	[412]	[463,536,513,566]	2	hSpCas9	negative selection	8905329
671144	671167	16	-	27260156	SU8686	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	0.496433949724723	[304]	[402,392,457,462]	8	hSpCas9	negative selection	8962324
671153	671176	16	+	27260156	SU8686	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.012307534799607889	[853]	[680,955,732,1078]	0	hSpCas9	negative selection	8962325
671963	671986	16	-	27260156	SU8686	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.2868721300377725	[351]	[534,373,376,402]	5	hSpCas9	negative selection	8962326
671865	671888	16	+	27260156	SU8686	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.23136780736283982	[352]	[390,409,401,444]	4	hSpCas9	negative selection	9026578
672084	672107	16	-	27260156	SU8686	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.4755302050501691	[578]	[799,786,665,956]	7	hSpCas9	negative selection	9026579
672114	672137	16	-	27260156	SU8686	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.010549096467494995	[412]	[413,356,331,574]	0	hSpCas9	negative selection	9026580
671144	671167	16	-	27260156	SKES1	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.0712432420788599	[304]	[410,280,300,189]	-1	hSpCas9	negative selection	9083575
671153	671176	16	+	27260156	SKES1	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.09877656357073306	[853]	[1123,965,786,811]	2	hSpCas9	negative selection	9083576
671963	671986	16	-	27260156	SKES1	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.1363653200456429	[351]	[346,339,364,237]	-3	hSpCas9	negative selection	9083577
671865	671888	16	+	27260156	SKES1	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.5710126418326963	[352]	[620,639,508,363]	9	hSpCas9	negative selection	9147829
672084	672107	16	-	27260156	SKES1	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.652795856727066	[578]	[1070,1000,913,695]	9	hSpCas9	negative selection	9147830
672114	672137	16	-	27260156	SKES1	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	0.21235955242597482	[412]	[540,482,469,425]	4	hSpCas9	negative selection	9147831
671144	671167	16	-	27260156	TOV112D	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.06432389757762047	[304]	[316,267,240,336]	-1	hSpCas9	negative selection	9204826
671153	671176	16	+	27260156	TOV112D	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	0.1828819282245292	[853]	[1169,1150,826,799]	3	hSpCas9	negative selection	9204827
671963	671986	16	-	27260156	TOV112D	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.1973600470607128	[351]	[333,430,297,201]	-4	hSpCas9	negative selection	9204828
671865	671888	16	+	27260156	TOV112D	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.03399868354598967	[352]	[375,541,183,389]	0	hSpCas9	negative selection	9269080
672084	672107	16	-	27260156	TOV112D	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.4571058544504085	[578]	[508,898,938,835]	8	hSpCas9	negative selection	9269081
672114	672137	16	-	27260156	TOV112D	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.428455681451555	[412]	[285,531,250,215]	-7	hSpCas9	negative selection	9269082
671144	671167	16	-	27260156	TC71	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.1030901718307542	[304]	[303,267,323,321]	-3	hSpCas9	negative selection	9326077
671153	671176	16	+	27260156	TC71	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.014180549218345218	[853]	[774,951,1011,884]	0	hSpCas9	negative selection	9326078
671963	671986	16	-	27260156	TC71	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	0.0030128124740408935	[351]	[325,306,454,425]	0	hSpCas9	negative selection	9326079
671865	671888	16	+	27260156	TC71	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	-0.06471370289641315	[352]	[301,389,407,345]	-2	hSpCas9	negative selection	9390331
672084	672107	16	-	27260156	TC71	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.39551171314761324	[578]	[845,769,676,986]	8	hSpCas9	negative selection	9390332
672114	672137	16	-	27260156	TC71	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.05500778591230682	[412]	[410,459,432,398]	-1	hSpCas9	negative selection	9390333
671144	671167	16	-	27260156	TC32	viability	CGCTGTAGCCGAAGCGCCGCAGG	RHOT2	ENSG00000140983	-0.3045929152071054	[304]	[321,79,334,242]	-5	hSpCas9	negative selection	9447328
671153	671176	16	+	27260156	TC32	viability	CTTCGGCTACAGCGATGCCCTGG	RHOT2	ENSG00000140983	-0.07807441624684663	[853]	[785,491,1052,817]	-1	hSpCas9	negative selection	9447329
671963	671986	16	-	27260156	TC32	viability	TCCGTGCAGGGGCAACCGGCCGG	RHOT2	ENSG00000140983	-0.21094579580339162	[351]	[279,217,316,345]	-4	hSpCas9	negative selection	9447330
671865	671888	16	+	27260156	TC32	viability	CGACGGCGCCCTCTCGCCCGTGG	RHOT2	ENSG00000140983	0.11539278629152355	[352]	[362,219,526,389]	2	hSpCas9	negative selection	9511582
672084	672107	16	-	27260156	TC32	viability	GGACGTCCAGGTAGGTCACCAGG	RHOT2	ENSG00000140983	0.5758750321552496	[578]	[733,413,1168,1123]	8	hSpCas9	negative selection	9511583
672114	672137	16	-	27260156	TC32	viability	CCAGGTAGCCTAGGTGTCCAAGG	RHOT2	ENSG00000140983	-0.1944999417626126	[412]	[290,161,410,573]	-4	hSpCas9	negative selection	9511584
668215	668238	16	+	27869803	HPAFII	viability after 27 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	0.06668470014993033	[334]	[268,113,NaN]	0	hSpCas9	negative selection	9558301
669540	669563	16	+	27869803	HPAFII	viability after 27 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.43506339185247667	[507]	[226,172,NaN]	-3	hSpCas9	negative selection	9558308
670245	670268	16	-	27869803	HPAFII	viability after 27 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.2916619765370949	[304]	[130,130,NaN]	-2	hSpCas9	negative selection	9558310
670452	670475	16	-	27869803	HPAFII	viability after 27 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.3385482893455002	[354]	[367,125,NaN]	2	hSpCas9	negative selection	9558312
670737	670760	16	-	27869803	HPAFII	viability after 27 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-1.0711709994270375	[104]	[22,28,NaN]	-6	hSpCas9	negative selection	9558318
671101	671124	16	+	27869803	HPAFII	viability after 27 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.2510507140714715	[16]	[20,1,NaN]	2	hSpCas9	negative selection	9558320
668215	668238	16	+	27869803	HPAFII	viability after 15 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.15404665480663654	[334]	[383,285,NaN]	-2	hSpCas9	negative selection	9640750
669540	669563	16	+	27869803	HPAFII	viability after 15 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.367584822913927	[507]	[572,329,NaN]	-4	hSpCas9	negative selection	9640757
670245	670268	16	-	27869803	HPAFII	viability after 15 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.0041790047261093255	[304]	[443,253,NaN]	0	hSpCas9	negative selection	9640759
670452	670475	16	-	27869803	HPAFII	viability after 15 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.2146443056523618	[354]	[615,334,NaN]	2	hSpCas9	negative selection	9640761
670737	670760	16	-	27869803	HPAFII	viability after 15 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.7724360254693479	[104]	[33,85,NaN]	-7	hSpCas9	negative selection	9640767
671101	671124	16	+	27869803	HPAFII	viability after 15 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.12704580253531583	[16]	[43,4,NaN]	1	hSpCas9	negative selection	9640769
668215	668238	16	+	27869803	ASPC1	viability after 36 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-1.856768110094429	[697]	[107,65,38]	-9	hSpCas9	negative selection	9723199
669540	669563	16	+	27869803	ASPC1	viability after 36 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.08971361344675122	[963]	[576,416,153]	0	hSpCas9	negative selection	9723206
670245	670268	16	-	27869803	ASPC1	viability after 36 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	0.03164064922444704	[806]	[594,178,155]	0	hSpCas9	negative selection	9723208
670452	670475	16	-	27869803	ASPC1	viability after 36 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.30399924995547445	[1059]	[325,647,391]	3	hSpCas9	negative selection	9723210
670737	670760	16	-	27869803	ASPC1	viability after 36 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	0.5090911027201312	[205]	[39,221,49]	5	hSpCas9	negative selection	9723216
671101	671124	16	+	27869803	ASPC1	viability after 36 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.4055391050966892	[67]	[0,6,149]	9	hSpCas9	negative selection	9723218
668215	668238	16	+	27869803	PATU8988S	viability after 35 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.9703541061911404	[685]	[145,135,NaN]	-7	hSpCas9	negative selection	9805648
669540	669563	16	+	27869803	PATU8988S	viability after 35 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-1.2085414252619657	[986]	[174,168,NaN]	-8	hSpCas9	negative selection	9805655
670245	670268	16	-	27869803	PATU8988S	viability after 35 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-1.1622086257823137	[811]	[201,89,NaN]	-8	hSpCas9	negative selection	9805657
670452	670475	16	-	27869803	PATU8988S	viability after 35 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.13347939167949951	[666]	[198,290,NaN]	-1	hSpCas9	negative selection	9805659
670737	670760	16	-	27869803	PATU8988S	viability after 35 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-1.0628354111294498	[227]	[24,62,NaN]	-7	hSpCas9	negative selection	9805665
671101	671124	16	+	27869803	PATU8988S	viability after 35 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.36988972079283045	[49]	[35,15,NaN]	4	hSpCas9	negative selection	9805667
668215	668238	16	+	27869803	PATU8988S	viability after 31 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.128583761224472	[685]	[119,415,NaN]	-1	hSpCas9	negative selection	9888097
669540	669563	16	+	27869803	PATU8988S	viability after 31 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.6048059526144705	[986]	[205,325,NaN]	-6	hSpCas9	negative selection	9888104
670245	670268	16	-	27869803	PATU8988S	viability after 31 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-0.8343131866745939	[811]	[141,231,NaN]	-7	hSpCas9	negative selection	9888106
670452	670475	16	-	27869803	PATU8988S	viability after 31 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	-0.21194875288948575	[666]	[149,330,NaN]	-2	hSpCas9	negative selection	9888108
670737	670760	16	-	27869803	PATU8988S	viability after 31 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-1.590076174226009	[227]	[16,46,NaN]	-8	hSpCas9	negative selection	9888114
671101	671124	16	+	27869803	PATU8988S	viability after 31 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.010252747757034886	[49]	[16,23,NaN]	0	hSpCas9	negative selection	9888116
668215	668238	16	+	27869803	HPAFII	viability after 35 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.22122976162086644	[334]	[168,118,NaN]	-1	hSpCas9	negative selection	9970546
669540	669563	16	+	27869803	HPAFII	viability after 35 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	-0.09448782889595286	[507]	[214,269,NaN]	0	hSpCas9	negative selection	9970553
670245	670268	16	-	27869803	HPAFII	viability after 35 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-1.2010024033437299	[304]	[37,99,NaN]	-6	hSpCas9	negative selection	9970555
670452	670475	16	-	27869803	HPAFII	viability after 35 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.7177267359190057	[354]	[478,88,NaN]	5	hSpCas9	negative selection	9970557
670737	670760	16	-	27869803	HPAFII	viability after 35 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.8090115431683773	[104]	[3,59,NaN]	-5	hSpCas9	negative selection	9970563
671101	671124	16	+	27869803	HPAFII	viability after 35 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	1.4002254708874347	[16]	[41,0,NaN]	8	hSpCas9	negative selection	9970565
668215	668238	16	+	27869803	HPAFII	viability after 31 days	CGCATCCTGTTACTGGGCGAGGG	RHOT2	ENSG00000140983	-0.529190090853852	[334]	[169,86,NaN]	-4	hSpCas9	negative selection	10052995
669540	669563	16	+	27869803	HPAFII	viability after 31 days	ACTGTTCCCTCAGGCAAACGTGG	RHOT2	ENSG00000140983	0.3592315078201569	[507]	[347,384,NaN]	2	hSpCas9	negative selection	10053002
670245	670268	16	-	27869803	HPAFII	viability after 31 days	CACTAGGATGATGGGCACCCTGG	RHOT2	ENSG00000140983	-1.0307848539516002	[304]	[89,76,NaN]	-6	hSpCas9	negative selection	10053004
670452	670475	16	-	27869803	HPAFII	viability after 31 days	TCAGGTTCTTGGCCGAACACTGG	RHOT2	ENSG00000140983	0.6283152278923599	[354]	[496,101,NaN]	4	hSpCas9	negative selection	10053006
670737	670760	16	-	27869803	HPAFII	viability after 31 days	GCTCTTCGTCACTGAGCGCCTGG	RHOT2	ENSG00000140983	-0.6386529228924955	[104]	[0,77,NaN]	-4	hSpCas9	negative selection	10053012
671101	671124	16	+	27869803	HPAFII	viability after 31 days	CGCTCTTCATCCAGCGCGGCCGG	RHOT2	ENSG00000140983	0.8979758564609877	[16]	[23,10,NaN]	6	hSpCas9	negative selection	10053014
668387	668410	16	+	28162770	P31FUJ	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.595372283799087	[224]	[174]	-5	hSpCas9	negative selection	10225167
672951	672974	16	-	28162770	P31FUJ	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.1462932111597035	[533]	[566]	-1	hSpCas9	negative selection	10225168
668491	668514	16	-	28162770	P31FUJ	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.6138923717698845	[55]	[42]	-5	hSpCas9	negative selection	10225169
668666	668689	16	+	28162770	P31FUJ	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-1.0747373581821271	[94]	[52]	-6	hSpCas9	negative selection	10225170
670285	670308	16	+	28162770	P31FUJ	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.88991449089137	[163]	[25]	-9	hSpCas9	negative selection	10225171
670347	670370	16	-	28162770	P31FUJ	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.2085546581677011	[235]	[119]	-7	hSpCas9	negative selection	10225172
670945	670968	16	+	28162770	P31FUJ	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.4217657637926444	[525]	[827]	5	hSpCas9	negative selection	10225173
671131	671154	16	-	28162770	P31FUJ	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.06354768071492489	[477]	[586]	0	hSpCas9	negative selection	10225174
672147	672170	16	-	28162770	P31FUJ	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	0.014290657550393604	[181]	[215]	0	hSpCas9	negative selection	10225175
672510	672533	16	-	28162770	P31FUJ	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.10351527400029559	[418]	[528]	1	hSpCas9	negative selection	10225176
668387	668410	16	+	28162770	TF1	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10394533
672951	672974	16	-	28162770	TF1	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	NaN	[NaN]	[482]	1	hSpCas9	negative selection	10394534
668491	668514	16	-	28162770	TF1	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10394535
668666	668689	16	+	28162770	TF1	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10394536
670285	670308	16	+	28162770	TF1	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10394537
670347	670370	16	-	28162770	TF1	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10394538
670945	670968	16	+	28162770	TF1	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10394539
671131	671154	16	-	28162770	TF1	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	NaN	[NaN]	[442]	1	hSpCas9	negative selection	10394540
672147	672170	16	-	28162770	TF1	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10394541
672510	672533	16	-	28162770	TF1	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	NaN	[NaN]	[294]	1	hSpCas9	negative selection	10394542
668387	668410	16	+	28162770	SKM1	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.2984397419649927	[63]	[45]	-7	hSpCas9	negative selection	10563899
672951	672974	16	-	28162770	SKM1	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.20948347478028773	[120]	[184]	-2	hSpCas9	negative selection	10563900
668491	668514	16	-	28162770	SKM1	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.6185708933639761	[20]	[56]	6	hSpCas9	negative selection	10563901
668666	668689	16	+	28162770	SKM1	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	1.6451243124052926	[16]	[93]	9	hSpCas9	negative selection	10563902
670285	670308	16	+	28162770	SKM1	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.1939704754089635	[21]	[16]	-7	hSpCas9	negative selection	10563903
670347	670370	16	-	28162770	SKM1	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.3049432618026531	[57]	[82]	-3	hSpCas9	negative selection	10563904
670945	670968	16	+	28162770	SKM1	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.19639721280350364	[139]	[215]	-2	hSpCas9	negative selection	10563905
671131	671154	16	-	28162770	SKM1	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.15254292321407592	[104]	[166]	-1	hSpCas9	negative selection	10563906
672147	672170	16	-	28162770	SKM1	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.0395931330946322	[49]	[42]	-6	hSpCas9	negative selection	10563907
672510	672533	16	-	28162770	SKM1	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.004378440510574233	[79]	[140]	0	hSpCas9	negative selection	10563908
668387	668410	16	+	28162770	SKM1	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.2984397419649927	[63]	[45]	-7	hSpCas9	negative selection	10733265
672951	672974	16	-	28162770	SKM1	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.20948347478028773	[120]	[184]	-2	hSpCas9	negative selection	10733266
668491	668514	16	-	28162770	SKM1	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.6185708933639761	[20]	[56]	6	hSpCas9	negative selection	10733267
668666	668689	16	+	28162770	SKM1	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	1.6451243124052926	[16]	[93]	9	hSpCas9	negative selection	10733268
670285	670308	16	+	28162770	SKM1	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.1939704754089635	[21]	[16]	-7	hSpCas9	negative selection	10733269
670347	670370	16	-	28162770	SKM1	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.3049432618026531	[57]	[82]	-3	hSpCas9	negative selection	10733270
670945	670968	16	+	28162770	SKM1	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.19639721280350364	[139]	[215]	-2	hSpCas9	negative selection	10733271
671131	671154	16	-	28162770	SKM1	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.15254292321407592	[104]	[166]	-1	hSpCas9	negative selection	10733272
672147	672170	16	-	28162770	SKM1	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.0395931330946322	[49]	[42]	-6	hSpCas9	negative selection	10733273
672510	672533	16	-	28162770	SKM1	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.004378440510574233	[79]	[140]	0	hSpCas9	negative selection	10733274
668387	668410	16	+	28162770	PL21	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.06904701832606888	[187]	[77]	0	hSpCas9	negative selection	10902631
672951	672974	16	-	28162770	PL21	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	0.24408296207691715	[387]	[199]	2	hSpCas9	negative selection	10902632
668491	668514	16	-	28162770	PL21	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.26452865251412416	[68]	[24]	-2	hSpCas9	negative selection	10902633
668666	668689	16	+	28162770	PL21	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	0.15707089259743423	[67]	[32]	1	hSpCas9	negative selection	10902634
670285	670308	16	+	28162770	PL21	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.072878879917096	[86]	[8]	-8	hSpCas9	negative selection	10902635
670347	670370	16	-	28162770	PL21	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.356589205502892	[252]	[42]	-7	hSpCas9	negative selection	10902636
670945	670968	16	+	28162770	PL21	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.9101973351920094	[367]	[300]	7	hSpCas9	negative selection	10902637
671131	671154	16	-	28162770	PL21	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.5480629179096268	[351]	[223]	5	hSpCas9	negative selection	10902638
672147	672170	16	-	28162770	PL21	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.4103579783389737	[170]	[27]	-7	hSpCas9	negative selection	10902639
672510	672533	16	-	28162770	PL21	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.17668064166533132	[247]	[121]	1	hSpCas9	negative selection	10902640
668387	668410	16	+	28162770	P31FUJ	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.595372283799087	[224]	[174]	-5	hSpCas9	negative selection	11071997
672951	672974	16	-	28162770	P31FUJ	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.1462932111597035	[533]	[566]	-1	hSpCas9	negative selection	11071998
668491	668514	16	-	28162770	P31FUJ	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.6138923717698845	[55]	[42]	-5	hSpCas9	negative selection	11071999
668666	668689	16	+	28162770	P31FUJ	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-1.0747373581821271	[94]	[52]	-6	hSpCas9	negative selection	11072000
670285	670308	16	+	28162770	P31FUJ	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.88991449089137	[163]	[25]	-9	hSpCas9	negative selection	11072001
670347	670370	16	-	28162770	P31FUJ	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.2085546581677011	[235]	[119]	-7	hSpCas9	negative selection	11072002
670945	670968	16	+	28162770	P31FUJ	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.4217657637926444	[525]	[827]	5	hSpCas9	negative selection	11072003
671131	671154	16	-	28162770	P31FUJ	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.06354768071492489	[477]	[586]	0	hSpCas9	negative selection	11072004
672147	672170	16	-	28162770	P31FUJ	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	0.014290657550393604	[181]	[215]	0	hSpCas9	negative selection	11072005
672510	672533	16	-	28162770	P31FUJ	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.10351527400029559	[418]	[528]	1	hSpCas9	negative selection	11072006
668387	668410	16	+	28162770	OCIAML5	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-3.230578194117727	[103]	[19]	-9	hSpCas9	negative selection	11241363
672951	672974	16	-	28162770	OCIAML5	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.9111458036180191	[323]	[310]	-5	hSpCas9	negative selection	11241364
668491	668514	16	-	28162770	OCIAML5	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.34724223735940973	[26]	[61]	3	hSpCas9	negative selection	11241365
668666	668689	16	+	28162770	OCIAML5	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-0.22130038052971612	[61]	[95]	-2	hSpCas9	negative selection	11241366
670285	670308	16	+	28162770	OCIAML5	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-0.801440497794029	[27]	[28]	-5	hSpCas9	negative selection	11241367
670347	670370	16	-	28162770	OCIAML5	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.0532064429718484	[145]	[126]	-6	hSpCas9	negative selection	11241368
670945	670968	16	+	28162770	OCIAML5	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.21066918448396565	[269]	[563]	1	hSpCas9	negative selection	11241369
671131	671154	16	-	28162770	OCIAML5	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.16716263226893435	[315]	[507]	-1	hSpCas9	negative selection	11241370
672147	672170	16	-	28162770	OCIAML5	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.1073236261060717	[110]	[92]	-6	hSpCas9	negative selection	11241371
672510	672533	16	-	28162770	OCIAML5	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.675671061164209	[119]	[345]	6	hSpCas9	negative selection	11241372
668387	668410	16	+	28162770	EOL1	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-2.57408992932625	[372]	[32]	-9	hSpCas9	negative selection	11410729
672951	672974	16	-	28162770	EOL1	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.36944344681370467	[536]	[218]	-3	hSpCas9	negative selection	11410730
668491	668514	16	-	28162770	EOL1	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.8092781150651044	[152]	[45]	-5	hSpCas9	negative selection	11410731
668666	668689	16	+	28162770	EOL1	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-2.122145463877507	[156]	[18]	-8	hSpCas9	negative selection	11410732
670285	670308	16	+	28162770	EOL1	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.691111526373538	[189]	[30]	-8	hSpCas9	negative selection	11410733
670347	670370	16	-	28162770	EOL1	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.7603956102473894	[462]	[143]	-5	hSpCas9	negative selection	11410734
670945	670968	16	+	28162770	EOL1	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.7673299330671336	[503]	[155]	-5	hSpCas9	negative selection	11410735
671131	671154	16	-	28162770	EOL1	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.6246140077227748	[397]	[135]	-4	hSpCas9	negative selection	11410736
672147	672170	16	-	28162770	EOL1	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.6131090143722648	[179]	[30]	-7	hSpCas9	negative selection	11410737
672510	672533	16	-	28162770	EOL1	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-2.6261990138127085	[374]	[31]	-9	hSpCas9	negative selection	11410738
668387	668410	16	+	28162770	MOLM13	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	0.11152778959334272	[264]	[206]	0	hSpCas9	negative selection	11580095
672951	672974	16	-	28162770	MOLM13	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	0.17662337993534005	[546]	[446]	1	hSpCas9	negative selection	11580096
668491	668514	16	-	28162770	MOLM13	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.8586793345767455	[89]	[117]	6	hSpCas9	negative selection	11580097
668666	668689	16	+	28162770	MOLM13	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	1.4349747590718438	[132]	[259]	9	hSpCas9	negative selection	11580098
670285	670308	16	+	28162770	MOLM13	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-0.6195734597057605	[135]	[63]	-4	hSpCas9	negative selection	11580099
670347	670370	16	-	28162770	MOLM13	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	0.8921160522780828	[312]	[419]	6	hSpCas9	negative selection	11580100
670945	670968	16	+	28162770	MOLM13	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.291656584774562	[600]	[354]	-2	hSpCas9	negative selection	11580101
671131	671154	16	-	28162770	MOLM13	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.9867329917525656	[505]	[724]	7	hSpCas9	negative selection	11580102
672147	672170	16	-	28162770	MOLM13	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	0.007048192652610141	[255]	[185]	0	hSpCas9	negative selection	11580103
672510	672533	16	-	28162770	MOLM13	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.26112319535753037	[351]	[304]	2	hSpCas9	negative selection	11580104
668387	668410	16	+	28162770	HEL	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.6494419194929535	[239]	[97]	-4	hSpCas9	negative selection	11749461
672951	672974	16	-	28162770	HEL	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.07280777853094367	[467]	[284]	0	hSpCas9	negative selection	11749462
668491	668514	16	-	28162770	HEL	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	0.7375980183417983	[102]	[109]	6	hSpCas9	negative selection	11749463
668666	668689	16	+	28162770	HEL	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	0.5457143776054925	[122]	[114]	4	hSpCas9	negative selection	11749464
670285	670308	16	+	28162770	HEL	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.0453171616849026	[144]	[44]	-6	hSpCas9	negative selection	11749465
670347	670370	16	-	28162770	HEL	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.18598974084981412	[356]	[200]	-1	hSpCas9	negative selection	11749466
670945	670968	16	+	28162770	HEL	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.4998655634424435	[509]	[230]	-3	hSpCas9	negative selection	11749467
671131	671154	16	-	28162770	HEL	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.23162703593531342	[366]	[275]	2	hSpCas9	negative selection	11749468
672147	672170	16	-	28162770	HEL	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.5083271421906396	[170]	[76]	-3	hSpCas9	negative selection	11749469
672510	672533	16	-	28162770	HEL	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.4889051738101139	[343]	[156]	-3	hSpCas9	negative selection	11749470
668387	668410	16	+	28162770	MV411	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.8037877725723979	[171]	[82]	-5	hSpCas9	negative selection	11918827
672951	672974	16	-	28162770	MV411	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-0.04941852214775433	[327]	[266]	0	hSpCas9	negative selection	11918828
668491	668514	16	-	28162770	MV411	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.6931839021382928	[118]	[61]	-5	hSpCas9	negative selection	11918829
668666	668689	16	+	28162770	MV411	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-0.5242934615441075	[69]	[40]	-4	hSpCas9	negative selection	11918830
670285	670308	16	+	28162770	MV411	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-2.1675999484960684	[95]	[17]	-8	hSpCas9	negative selection	11918831
670347	670370	16	-	28162770	MV411	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-0.6160604493123627	[261]	[143]	-4	hSpCas9	negative selection	11918832
670945	670968	16	+	28162770	MV411	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-1.5680087836283767	[446]	[126]	-7	hSpCas9	negative selection	11918833
671131	671154	16	-	28162770	MV411	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.7054271952461661	[272]	[374]	6	hSpCas9	negative selection	11918834
672147	672170	16	-	28162770	MV411	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.5952504443871096	[216]	[120]	-4	hSpCas9	negative selection	11918835
672510	672533	16	-	28162770	MV411	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.3523829086654937	[243]	[160]	-3	hSpCas9	negative selection	11918836
668387	668410	16	+	28162770	MONOMAC1	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.7879241817378151	[121]	[80]	-6	hSpCas9	negative selection	12088193
672951	672974	16	-	28162770	MONOMAC1	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	0.8897244648597299	[241]	[513]	7	hSpCas9	negative selection	12088194
668491	668514	16	-	28162770	MONOMAC1	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.22806374268017815	[46]	[45]	-2	hSpCas9	negative selection	12088195
668666	668689	16	+	28162770	MONOMAC1	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	0.41489270126187194	[52]	[80]	4	hSpCas9	negative selection	12088196
670285	670308	16	+	28162770	MONOMAC1	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-0.659380061116754	[61]	[44]	-5	hSpCas9	negative selection	12088197
670347	670370	16	-	28162770	MONOMAC1	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	0.03244499906321385	[173]	[203]	0	hSpCas9	negative selection	12088198
670945	670968	16	+	28162770	MONOMAC1	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	0.22187366136649667	[278]	[372]	2	hSpCas9	negative selection	12088199
671131	671154	16	-	28162770	MONOMAC1	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.2758152873400651	[213]	[296]	2	hSpCas9	negative selection	12088200
672147	672170	16	-	28162770	MONOMAC1	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-1.1245243472751856	[96]	[50]	-7	hSpCas9	negative selection	12088201
672510	672533	16	-	28162770	MONOMAC1	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-0.08089525245040052	[166]	[180]	0	hSpCas9	negative selection	12088202
668387	668410	16	+	28162770	OCIAML2	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-1.082359235526103	[33]	[88]	-6	hSpCas9	negative selection	12257559
672951	672974	16	-	28162770	OCIAML2	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	-1.0869255327681089	[63]	[166]	-6	hSpCas9	negative selection	12257560
668491	668514	16	-	28162770	OCIAML2	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-1.1976113308357452	[11]	[28]	-7	hSpCas9	negative selection	12257561
668666	668689	16	+	28162770	OCIAML2	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-1.4706298252421615	[7]	[15]	-7	hSpCas9	negative selection	12257562
670285	670308	16	+	28162770	OCIAML2	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-1.9966986369097488	[17]	[24]	-8	hSpCas9	negative selection	12257563
670347	670370	16	-	28162770	OCIAML2	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	-1.286205254104734	[43]	[99]	-7	hSpCas9	negative selection	12257564
670945	670968	16	+	28162770	OCIAML2	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.33781799681694835	[69]	[306]	-3	hSpCas9	negative selection	12257565
671131	671154	16	-	28162770	OCIAML2	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	-0.6073661620339007	[46]	[170]	-4	hSpCas9	negative selection	12257566
672147	672170	16	-	28162770	OCIAML2	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	-0.9029453159528408	[27]	[82]	-6	hSpCas9	negative selection	12257567
672510	672533	16	-	28162770	OCIAML2	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	-1.2482374039057136	[44]	[104]	-7	hSpCas9	negative selection	12257568
668387	668410	16	+	28162770	OCIAML3	viability	GGTGGGCGAGGAGTTCCCCGAGG	RHOT2	ENSG00000140983	-0.3113686765508579	[66]	[162]	-2	hSpCas9	negative selection	12426925
672951	672974	16	-	28162770	OCIAML3	viability	TGGAGGAGACAAAGAGGCAGGGG	RHOT2	ENSG00000140983	0.012649931496311995	[109]	[334]	0	hSpCas9	negative selection	12426926
668491	668514	16	-	28162770	OCIAML3	viability	GTGATCTCCTCCGCGCGGGGAGG	RHOT2	ENSG00000140983	-0.9310426276017338	[11]	[18]	-6	hSpCas9	negative selection	12426927
668666	668689	16	+	28162770	OCIAML3	viability	GACGGACGAGGAGCTGCGGGAGG	RHOT2	ENSG00000140983	-0.9810307634334101	[16]	[25]	-6	hSpCas9	negative selection	12426928
670285	670308	16	+	28162770	OCIAML3	viability	GCGGTCGGGGAGCTCCATGGAGG	RHOT2	ENSG00000140983	-0.6680082217679402	[19]	[37]	-5	hSpCas9	negative selection	12426929
670347	670370	16	-	28162770	OCIAML3	viability	GGACCTACTCACCTCCACGCAGG	RHOT2	ENSG00000140983	1.0542807957658222	[51]	[325]	8	hSpCas9	negative selection	12426930
670945	670968	16	+	28162770	OCIAML3	viability	GGTGGTGTGCAGGAACGTGGCGG	RHOT2	ENSG00000140983	-0.11483980362560375	[131]	[367]	-1	hSpCas9	negative selection	12426931
671131	671154	16	-	28162770	OCIAML3	viability	GCGCCGCAGGATGGTCCAGGTGG	RHOT2	ENSG00000140983	0.10292329203979034	[94]	[307]	1	hSpCas9	negative selection	12426932
672147	672170	16	-	28162770	OCIAML3	viability	GGGCCTGGTCCTGCTCACAGAGG	RHOT2	ENSG00000140983	1.0517088914760893	[30]	[193]	8	hSpCas9	negative selection	12426933
672510	672533	16	-	28162770	OCIAML3	viability	GTGTCGATGGCGTAGCCGGGAGG	RHOT2	ENSG00000140983	0.6268685485649048	[67]	[316]	6	hSpCas9	negative selection	12426934