Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7732
• Symbol: RNF112
• Description: ring finger protein 112

DataSource: http://genomecrispr.dkfz.de/#!/results/RNF112

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
19411419	19411442	17	-	26472758	Jiyoye	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.013511533019596511	[267]	[203]	0	hSpCas9	negative selection	137815
19413582	19413605	17	+	26472758	Jiyoye	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.1687702458578488	[318]	[106]	-7	hSpCas9	negative selection	137816
19414848	19414871	17	+	26472758	Jiyoye	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.8515588868942949	[66]	[27]	-5	hSpCas9	negative selection	137817
19415186	19415209	17	+	26472758	Jiyoye	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-1.9713362417478564	[25]	[4]	-8	hSpCas9	negative selection	137818
19411406	19411429	17	-	26472758	Jiyoye	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	-1.0325241720072396	[235]	[86]	-6	hSpCas9	negative selection	137819
19411419	19411442	17	-	26472758	KBM7	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.5675757461071392	[1089,795]	[973,359]	6	hSpCas9	negative selection	328933
19413582	19413605	17	+	26472758	KBM7	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-0.7540382876244838	[807,588]	[96,277]	-6	hSpCas9	negative selection	328934
19414848	19414871	17	+	26472758	KBM7	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.47904460377432057	[180,147]	[60,49]	-4	hSpCas9	negative selection	328935
19415186	19415209	17	+	26472758	KBM7	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	1.323895225542535	[51,86]	[68,97]	9	hSpCas9	negative selection	328936
19411406	19411429	17	-	26472758	KBM7	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.6368563215673099	[489,453]	[346,343]	7	hSpCas9	negative selection	328937
19411419	19411442	17	-	26472758	Raji	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.8930172545760695	[477]	[205]	7	hSpCas9	negative selection	520051
19413582	19413605	17	+	26472758	Raji	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-0.28983268681800006	[294]	[55]	-2	hSpCas9	negative selection	520052
19414848	19414871	17	+	26472758	Raji	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.7267795331586296	[137]	[52]	6	hSpCas9	negative selection	520053
19415186	19415209	17	+	26472758	Raji	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	0.9147384574312039	[47]	[20]	8	hSpCas9	negative selection	520054
19411406	19411429	17	-	26472758	Raji	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.09010554394176395	[335]	[82]	0	hSpCas9	negative selection	520055
19411419	19411442	17	-	26472758	K562	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.7080749321654695	[743]	[1025]	6	hSpCas9	negative selection	711169
19413582	19413605	17	+	26472758	K562	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-2.440524654151477	[462]	[71]	-8	hSpCas9	negative selection	711170
19414848	19414871	17	+	26472758	K562	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.6484851091242876	[98]	[130]	5	hSpCas9	negative selection	711171
19415186	19415209	17	+	26472758	K562	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-1.8430441135838924	[84]	[19]	-7	hSpCas9	negative selection	711172
19411406	19411429	17	-	26472758	K562	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.516790998079577	[384]	[464]	4	hSpCas9	negative selection	711173
19413580	19413603	17	+	26627737	DLD1	viability	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.2666559187889519	[134]	[50,32,22]	-3	hSpCas9	negative selection	796483
19414112	19414135	17	+	26627737	DLD1	viability	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.03189103253494702	[635]	[127,169,295]	0	hSpCas9	negative selection	796484
19414472	19414495	17	+	26627737	DLD1	viability	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.6402525195124771	[179]	[27,28,48]	-6	hSpCas9	negative selection	796485
19414848	19414871	17	+	26627737	DLD1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.7052645129859669	[199]	[59,123,119]	7	hSpCas9	negative selection	796486
19413580	19413603	17	+	26627737	GBM cells	viability after 5 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.42942859158446556	[8]	[8,3]	6	hSpCas9	negative selection	878798
19414112	19414135	17	+	26627737	GBM cells	viability after 5 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.656998895284419	[216]	[165,200]	8	hSpCas9	negative selection	878799
19414472	19414495	17	+	26627737	GBM cells	viability after 5 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.4117265898510065	[81]	[73,42]	6	hSpCas9	negative selection	878800
19414848	19414871	17	+	26627737	GBM cells	viability after 5 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-1.3796216244882962	[130]	[26,26]	-9	hSpCas9	negative selection	878801
19413580	19413603	17	+	26627737	GBM cells	viability after 13 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.15804501319162956	[8]	[5,4]	2	hSpCas9	negative selection	961113
19414112	19414135	17	+	26627737	GBM cells	viability after 13 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.379879771634331	[216]	[150,154]	5	hSpCas9	negative selection	961114
19414472	19414495	17	+	26627737	GBM cells	viability after 13 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.4197254113794482	[81]	[53,63]	5	hSpCas9	negative selection	961115
19414848	19414871	17	+	26627737	GBM cells	viability after 13 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.754463295565075	[130]	[29,51]	-7	hSpCas9	negative selection	961116
19413580	19413603	17	+	26627737	GBM cells	viability after 21 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.45511531103402536	[8]	[1,4]	-4	hSpCas9	negative selection	1043428
19414112	19414135	17	+	26627737	GBM cells	viability after 21 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.7706107524060037	[216]	[209,192]	7	hSpCas9	negative selection	1043429
19414472	19414495	17	+	26627737	GBM cells	viability after 21 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.6590458788913346	[81]	[73,66]	6	hSpCas9	negative selection	1043430
19414848	19414871	17	+	26627737	GBM cells	viability after 21 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.5473398347268119	[130]	[43,52]	-5	hSpCas9	negative selection	1043431
19413580	19413603	17	+	26627737	RPE1	viability after 9 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-1.0283385167161174	[224]	[20,51]	-6	hSpCas9	negative selection	1125743
19414112	19414135	17	+	26627737	RPE1	viability after 9 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.6805438389698102	[576]	[268,315]	4	hSpCas9	negative selection	1125744
19414472	19414495	17	+	26627737	RPE1	viability after 9 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.0596383673792227	[261]	[218,108]	6	hSpCas9	negative selection	1125745
19414848	19414871	17	+	26627737	RPE1	viability after 9 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.12731104040684293	[279]	[124,57]	0	hSpCas9	negative selection	1125746
19413580	19413603	17	+	26627737	RPE1	viability after 12 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-1.9568403768245768	[224]	[17,12]	-8	hSpCas9	negative selection	1208058
19414112	19414135	17	+	26627737	RPE1	viability after 12 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	1.0893814387441665	[576]	[341,316]	6	hSpCas9	negative selection	1208059
19414472	19414495	17	+	26627737	RPE1	viability after 12 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.8665476055913224	[261]	[245,267]	8	hSpCas9	negative selection	1208060
19414848	19414871	17	+	26627737	RPE1	viability after 12 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6042314074900701	[279]	[14,85]	-4	hSpCas9	negative selection	1208061
19413580	19413603	17	+	26627737	RPE1	viability after 15 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.7769441048960213	[224]	[28,44]	-5	hSpCas9	negative selection	1290373
19414112	19414135	17	+	26627737	RPE1	viability after 15 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.5246294250823215	[576]	[273,196]	3	hSpCas9	negative selection	1290374
19414472	19414495	17	+	26627737	RPE1	viability after 15 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	2.4589580916876375	[261]	[435,379]	9	hSpCas9	negative selection	1290375
19414848	19414871	17	+	26627737	RPE1	viability after 15 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.631180612565814	[279]	[168,77]	4	hSpCas9	negative selection	1290376
19413580	19413603	17	+	26627737	RPE1	viability after 18 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-2.2236732129752026	[224]	[12,12]	-8	hSpCas9	negative selection	1372688
19414112	19414135	17	+	26627737	RPE1	viability after 18 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.7401607117436896	[576]	[160,365]	4	hSpCas9	negative selection	1372689
19414472	19414495	17	+	26627737	RPE1	viability after 18 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	2.7027011429259042	[261]	[512,403]	9	hSpCas9	negative selection	1372690
19414848	19414871	17	+	26627737	RPE1	viability after 18 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6447153229228499	[279]	[57,37]	-4	hSpCas9	negative selection	1372691
19413580	19413603	17	+	26627737	HeLa	viability after 8 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.23513110801030923	[783]	[344,325,215]	-2	hSpCas9	negative selection	1455003
19414112	19414135	17	+	26627737	HeLa	viability after 8 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.3444758097554088	[303]	[188,158,160]	3	hSpCas9	negative selection	1455004
19414472	19414495	17	+	26627737	HeLa	viability after 8 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.7652129641916995	[136]	[158,16,137]	6	hSpCas9	negative selection	1455005
19414848	19414871	17	+	26627737	HeLa	viability after 8 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.18279681393859476	[313]	[110,200,51]	-2	hSpCas9	negative selection	1455006
19413580	19413603	17	+	26627737	HeLa	viability after 12 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.06557021813237007	[783]	[188,387,339]	0	hSpCas9	negative selection	1537318
19414112	19414135	17	+	26627737	HeLa	viability after 12 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.5025980167414548	[303]	[102,260,158]	4	hSpCas9	negative selection	1537319
19414472	19414495	17	+	26627737	HeLa	viability after 12 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.7529500186632352	[136]	[68,12,21]	-6	hSpCas9	negative selection	1537320
19414848	19414871	17	+	26627737	HeLa	viability after 12 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6063649570616654	[313]	[87,120,42]	-5	hSpCas9	negative selection	1537321
19413580	19413603	17	+	26627737	HeLa	viability after 15 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.5029464778761854	[783]	[151,318,203]	-4	hSpCas9	negative selection	1619633
19414112	19414135	17	+	26627737	HeLa	viability after 15 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	1.283656427919366	[303]	[156,359,395]	8	hSpCas9	negative selection	1619634
19414472	19414495	17	+	26627737	HeLa	viability after 15 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.10411384297481496	[136]	[108,48,17]	0	hSpCas9	negative selection	1619635
19414848	19414871	17	+	26627737	HeLa	viability after 15 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6945275829592785	[313]	[21,120,95]	-6	hSpCas9	negative selection	1619636
19413580	19413603	17	+	26627737	HeLa	viability after 18 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.5026145694182202	[783]	[98,267,203]	-4	hSpCas9	negative selection	1701948
19414112	19414135	17	+	26627737	HeLa	viability after 18 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	1.299293165696962	[303]	[106,303,395]	8	hSpCas9	negative selection	1701949
19414472	19414495	17	+	26627737	HeLa	viability after 18 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.06149759491479956	[136]	[70,38,17]	0	hSpCas9	negative selection	1701950
19414848	19414871	17	+	26627737	HeLa	viability after 18 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6881019247184097	[313]	[13,101,95]	-6	hSpCas9	negative selection	1701951
19413580	19413603	17	+	26627737	HCT116	viability after 6 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.21689335027704035	[565]	[53,88]	-1	hSpCas9	negative selection	1784263
19414112	19414135	17	+	26627737	HCT116	viability after 6 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	1.435456807570675	[383]	[384,40]	7	hSpCas9	negative selection	1784264
19414472	19414495	17	+	26627737	HCT116	viability after 6 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.7056527140240085	[81]	[11,25]	4	hSpCas9	negative selection	1784265
19414848	19414871	17	+	26627737	HCT116	viability after 6 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.08853924115759437	[432]	[63,76]	0	hSpCas9	negative selection	1784266
19413580	19413603	17	+	26627737	HCT116	viability after 8 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.3220775107263002	[680]	[243,313,340]	-4	hSpCas9	negative selection	1866578
19414112	19414135	17	+	26627737	HCT116	viability after 8 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.4733967695173096	[464]	[165,175,210]	-5	hSpCas9	negative selection	1866579
19414472	19414495	17	+	26627737	HCT116	viability after 8 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.674579847957977	[30]	[70,47,44]	9	hSpCas9	negative selection	1866580
19414848	19414871	17	+	26627737	HCT116	viability after 8 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.4412737024407219	[161]	[193,138,32]	4	hSpCas9	negative selection	1866581
19413580	19413603	17	+	26627737	HCT116	viability after 9 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.4592542824908892	[565]	[143,82]	-3	hSpCas9	negative selection	1948893
19414112	19414135	17	+	26627737	HCT116	viability after 9 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	1.0554079943816685	[383]	[111,292]	7	hSpCas9	negative selection	1948894
19414472	19414495	17	+	26627737	HCT116	viability after 9 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.3280884049639354	[81]	[121,1]	8	hSpCas9	negative selection	1948895
19414848	19414871	17	+	26627737	HCT116	viability after 9 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.9080795956973732	[432]	[50,69]	-6	hSpCas9	negative selection	1948896
19413580	19413603	17	+	26627737	HCT116	viability after 12 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.3725482727283188	[680]	[127,220,491]	-4	hSpCas9	negative selection	2031208
19414112	19414135	17	+	26627737	HCT116	viability after 12 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.5697928206262537	[464]	[76,180,243]	-6	hSpCas9	negative selection	2031209
19414472	19414495	17	+	26627737	HCT116	viability after 12 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.7613388852043819	[30]	[44,30,89]	9	hSpCas9	negative selection	2031210
19414848	19414871	17	+	26627737	HCT116	viability after 12 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.6570704952705957	[161]	[237,66,86]	6	hSpCas9	negative selection	2031211
19413580	19413603	17	+	26627737	HCT116	viability after 15 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.47933081067512195	[680]	[142,328,351]	-5	hSpCas9	negative selection	2113523
19414112	19414135	17	+	26627737	HCT116	viability after 15 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.49129398487524545	[464]	[131,168,260]	-5	hSpCas9	negative selection	2113524
19414472	19414495	17	+	26627737	HCT116	viability after 15 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.5865551708246193	[30]	[53,13,91]	9	hSpCas9	negative selection	2113525
19414848	19414871	17	+	26627737	HCT116	viability after 15 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.7505422023244032	[161]	[183,138,149]	6	hSpCas9	negative selection	2113526
19413580	19413603	17	+	26627737	HCT116	viability after 18 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.21931709129909605	[680]	[160,361,639]	2	hSpCas9	negative selection	2195838
19414112	19414135	17	+	26627737	HCT116	viability after 18 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.582692126151475	[464]	[93,192,160]	-5	hSpCas9	negative selection	2195839
19414472	19414495	17	+	26627737	HCT116	viability after 18 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	1.0716008973895041	[30]	[22,4,69]	8	hSpCas9	negative selection	2195840
19414848	19414871	17	+	26627737	HCT116	viability after 18 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	1.0081432749897548	[161]	[270,132,65]	7	hSpCas9	negative selection	2195841
19411395	19411418	17	+	24336569	HL60	viability	CATCCCAGCCTCCCATGCCAAGG	RNF112	ENSG00000128482	0.5425202889214437	[230]	[711]	5	hSpCas9	negative selection	2289878
19411406	19411429	17	-	24336569	HL60	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.4112043788727803	[510]	[1437]	4	hSpCas9	negative selection	2289879
19411412	19411435	17	-	24336569	HL60	viability	GTGACTGACAAGGCGGGCCTTGG	RNF112	ENSG00000128482	-0.5044529300351781	[1030]	[1537]	-4	hSpCas9	negative selection	2289880
19411418	19411441	17	-	24336569	HL60	viability	AAGGAAGTGACTGACAAGGCGGG	RNF112	ENSG00000128482	-0.5036971013119445	[66]	[99]	-4	hSpCas9	negative selection	2289881
19411440	19411463	17	+	24336569	HL60	viability	TTTGTCATCGGCTTGGCAAACGG	RNF112	ENSG00000128482	0.3215605823670564	[1009]	[2670]	3	hSpCas9	negative selection	2289882
19411639	19411662	17	+	24336569	HL60	viability	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	0.25037946312354875	[869]	[2189]	2	hSpCas9	negative selection	2289883
19411649	19411672	17	+	24336569	HL60	viability	TGGGAAACAGCGGCAACAGTTGG	RNF112	ENSG00000128482	-0.7377376529332988	[958]	[1216]	-6	hSpCas9	negative selection	2289884
19411395	19411418	17	+	24336569	KBM7	viability	CATCCCAGCCTCCCATGCCAAGG	RNF112	ENSG00000128482	-0.30950306114591	[228]	[503]	-3	hSpCas9	negative selection	2357055
19411406	19411429	17	-	24336569	KBM7	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	-0.32855509340660805	[499]	[1085]	-3	hSpCas9	negative selection	2357056
19411412	19411435	17	-	24336569	KBM7	viability	GTGACTGACAAGGCGGGCCTTGG	RNF112	ENSG00000128482	0.9382511236475314	[604]	[3161]	7	hSpCas9	negative selection	2357057
19411418	19411441	17	-	24336569	KBM7	viability	AAGGAAGTGACTGACAAGGCGGG	RNF112	ENSG00000128482	-1.902145060014364	[147]	[107]	-8	hSpCas9	negative selection	2357058
19411440	19411463	17	+	24336569	KBM7	viability	TTTGTCATCGGCTTGGCAAACGG	RNF112	ENSG00000128482	1.0847990857805931	[609]	[3528]	8	hSpCas9	negative selection	2357059
19411639	19411662	17	+	24336569	KBM7	viability	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	-0.409515429917753	[878]	[1804]	-3	hSpCas9	negative selection	2357060
19411649	19411672	17	+	24336569	KBM7	viability	TGGGAAACAGCGGCAACAGTTGG	RNF112	ENSG00000128482	0.22087761968703368	[620]	[1973]	2	hSpCas9	negative selection	2357061
19411640	19411663	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	0.2936506393539813	[3,3]	[4,3]	6	hSpCas9	positive selection	3017116
19413384	19413407	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	-1.1666798561982639	[2,2]	[0,0]	-9	hSpCas9	positive selection	3017117
19414449	19414472	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	-0.09803952213998623	[4,4]	[4,2]	-1	hSpCas9	positive selection	3017118
19411640	19411663	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	-0.5583366022633716	[3,3]	[3,0]	-7	hSpCas9	positive selection	3084974
19413384	19413407	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	-0.8442790745331494	[2,2]	[0,0]	-9	hSpCas9	positive selection	3084975
19414449	19414472	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	0.2764525954569246	[4,4]	[4,3]	5	hSpCas9	positive selection	3084976
19411629	19411652		+	24336571	A375	resistance to PLX after 7 days	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	-0.16439874273829314	[5,4]	[3,4]	-5	hSpCas9	positive selection	3141181
19411629	19411652		+	24336571	A375	resistance to PLX after 14 days	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.1445783655406052	[6,4]	[2,2]	1	hSpCas9	positive selection	3198974
19411629	19411652		+	24336571	A375	viability after 7 days	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.0353183488228932	[4]	[5,4]	0	hSpCas9	negative selection	3256767
19411629	19411652		+	24336571	A375	viability after 14 days	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.15909457768085744	[4]	[6,4]	2	hSpCas9	negative selection	3314560
19413356	19413379	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-2.455200788993988	[838,838]	[0,0]	-9	hSpCas9	positive selection	3390045
19411629	19411652	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.26864152467366925	[126,126]	[0,0]	1	hSpCas9	positive selection	3390046
19411639	19411662	17	+	26780180	HT29	viability (Avana library 4 designs)	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	0.832076792183803	[]	[]	3	hSpCas9	negative selection	3455487
19413383	19413406	17	+	26780180	HT29	viability (Avana library 4 designs)	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	1.30119788439972	[]	[]	5	hSpCas9	negative selection	3455488
19414448	19414471	17	+	26780180	HT29	viability (Avana library 4 designs)	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	0.260769231880564	[]	[]	0	hSpCas9	negative selection	3455489
19414448	19414471	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	6.2545676938664	[]	[]	9	hSpCas9	negative selection	3553500
19411639	19411662	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	3.87632224247363	[]	[]	6	hSpCas9	negative selection	3553501
19413383	19413406	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	-0.62578118488565	[]	[]	-1	hSpCas9	negative selection	3553502
19413561	19413584	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTACCCCCTGCATAGGTGGCGG	RNF112	ENSG00000128482	2.45868881085377	[]	[]	3	hSpCas9	negative selection	3553503
19414448	19414471	17	+	26780180	A375	viability (Avana lentiGuide)	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	-5.82530101431328	[]	[]	-8	hSpCas9	negative selection	3662159
19411639	19411662	17	+	26780180	A375	viability (Avana lentiGuide)	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	-3.55507269046263	[]	[]	-6	hSpCas9	negative selection	3662160
19413383	19413406	17	+	26780180	A375	viability (Avana lentiGuide)	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	6.10306426232307	[]	[]	5	hSpCas9	negative selection	3662161
19413561	19413584	17	+	26780180	A375	viability (Avana lentiGuide)	CCTACCCCCTGCATAGGTGGCGG	RNF112	ENSG00000128482	0.760635182820705	[]	[]	0	hSpCas9	negative selection	3662162
19414448	19414471	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	0.3134521569289139	[5]	[7,6]	8	hSpCas9	positive selection	3770766
19411639	19411662	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	-0.17924025287877568	[4]	[4,2]	-3	hSpCas9	positive selection	3770767
19413383	19413406	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	-0.147767515226288	[4]	[4,3]	-2	hSpCas9	positive selection	3770768
19413561	19413584	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTACCCCCTGCATAGGTGGCGG	RNF112	ENSG00000128482	0.2814870839034723	[4]	[5,5]	7	hSpCas9	positive selection	3770769
19414448	19414471	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTTTGTCCACGTGGCCGAGG	RNF112	ENSG00000128482	0.27569043520735603	[6]	[6,6]	7	hSpCas9	positive selection	3879373
19411639	19411662	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAGCTTCATGGGAAACAGCGG	RNF112	ENSG00000128482	0.1483058952909572	[4]	[5,4]	3	hSpCas9	positive selection	3879374
19413383	19413406	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTCTTGCTGGGGAAAGAAGGG	RNF112	ENSG00000128482	-0.6303861538427726	[3]	[0,2]	-7	hSpCas9	positive selection	3879375
19413561	19413584	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTACCCCCTGCATAGGTGGCGG	RNF112	ENSG00000128482	-0.7458642573575369	[4]	[1,2]	-7	hSpCas9	positive selection	3879376
19413356	19413379	17	-	26780180	A375	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.816287929963872	[]	[]	3	hSpCas9	negative selection	3989489
19411629	19411652	17	+	26780180	A375	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.63592965798206	[]	[]	2	hSpCas9	negative selection	3989490
19413340	19413363	17	+	26780180	A375	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.776659197504213	[]	[]	3	hSpCas9	negative selection	3989491
19413356	19413379	17	-	26780180	HT29	viability (GeCKOv2 library)	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.906899079928235	[]	[]	4	hSpCas9	negative selection	4097455
19411629	19411652	17	+	26780180	HT29	viability (GeCKOv2 library)	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.840881834925767	[]	[]	3	hSpCas9	negative selection	4097456
19413340	19413363	17	+	26780180	HT29	viability (GeCKOv2 library)	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.267684608309483	[]	[]	0	hSpCas9	negative selection	4097457
19411629	19411652	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	-0.291568985835321	[2]	[0,1]	-6	hSpCas9	positive selection	4166691
19411629	19411652	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	-0.8742301791588831	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4230713
19413340	19413363	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.1396753620480911	[3]	[3,0]	-3	hSpCas9	positive selection	4295101
19413356	19413379	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.06743497044677155	[4]	[3,3]	-1	hSpCas9	positive selection	4359354
19411629	19411652	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.22281880475095242	[2]	[3,1]	4	hSpCas9	positive selection	4359355
19413354	19413376	17	+	27760321	OCIAML3	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	-0.261307730111041	[465,391]	[277,279]	-3	hSpCas9	negative selection	4434995
19414465	19414487	17	-	27760321	OCIAML3	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.3632693473350858	[450,358]	[196,306]	-4	hSpCas9	negative selection	4434996
19414594	19414616	17	-	27760321	OCIAML3	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	-0.40916563007881623	[210,143]	[104,100]	-4	hSpCas9	negative selection	4434997
19413354	19413376	17	+	27760321	OCIAML2	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.19274648773649888	[465,391]	[373,422]	2	hSpCas9	negative selection	4518458
19414465	19414487	17	-	27760321	OCIAML2	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	0.02372043131065031	[450,358]	[302,367]	0	hSpCas9	negative selection	4518459
19414594	19414616	17	-	27760321	OCIAML2	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.898402256192673	[210,143]	[228,310]	9	hSpCas9	negative selection	4518460
19413354	19413376	17	+	27760321	MV411	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.7700203782548843	[465,391]	[639,241]	5	hSpCas9	negative selection	4601921
19414465	19414487	17	-	27760321	MV411	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.26357500910976805	[450,358]	[86,422]	-2	hSpCas9	negative selection	4601922
19414594	19414616	17	-	27760321	MV411	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	1.224090282820671	[210,143]	[378,106]	8	hSpCas9	negative selection	4601923
19413354	19413376	17	+	27760321	HL60	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.6913808328795232	[465,391]	[538,589]	7	hSpCas9	negative selection	4685384
19414465	19414487	17	-	27760321	HL60	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	0.23380483850425823	[450,358]	[276,502]	3	hSpCas9	negative selection	4685385
19414594	19414616	17	-	27760321	HL60	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.18673092216381093	[210,143]	[146,179]	2	hSpCas9	negative selection	4685386
19413354	19413376	17	+	27760321	HT1080	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	-0.567638554897588	[391,305]	[152,28]	-3	hSpCas9	negative selection	4768847
19414465	19414487	17	-	27760321	HT1080	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.07459511539475683	[358,279]	[138,100]	0	hSpCas9	negative selection	4768848
19414594	19414616	17	-	27760321	HT1080	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	1.188457701295534	[143,112]	[99,134]	6	hSpCas9	negative selection	4768849
19413354	19413376	17	+	27760321	HT29	viability after 7 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.5023110261217125	[391,305]	[557,706,629]	7	hSpCas9	negative selection	4852310
19414465	19414487	17	-	27760321	HT29	viability after 7 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	0.006326718754517929	[358,279]	[236,368,599]	0	hSpCas9	negative selection	4852311
19414594	19414616	17	-	27760321	HT29	viability after 7 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.8291661232455534	[143,112]	[223,494,155]	9	hSpCas9	negative selection	4852312
19413354	19413376	17	+	27760321	HT29	viability after 25 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.6601664086890975	[391,305]	[592,653,646]	7	hSpCas9	negative selection	4935773
19414465	19414487	17	-	27760321	HT29	viability after 25 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	0.2386635756615131	[358,279]	[381,514,393]	2	hSpCas9	negative selection	4935774
19414594	19414616	17	-	27760321	HT29	viability after 25 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	-0.04978876448720326	[143,112]	[60,215,154]	0	hSpCas9	negative selection	4935775
19413354	19413376	17	+	27760321	HT29	viability after 22 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.6369712833954047	[391,305]	[537,680,665]	7	hSpCas9	negative selection	5019236
19414465	19414487	17	-	27760321	HT29	viability after 22 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.07644173653667857	[358,279]	[212,338,503]	-1	hSpCas9	negative selection	5019237
19414594	19414616	17	-	27760321	HT29	viability after 22 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.2068432095736381	[143,112]	[157,173,182]	2	hSpCas9	negative selection	5019238
19413354	19413376	17	+	27760321	HT29	viability after 19 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.29288335074398086	[391,305]	[368,593,490]	2	hSpCas9	negative selection	5102699
19414465	19414487	17	-	27760321	HT29	viability after 19 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.4420622190601326	[358,279]	[443,218,165]	-4	hSpCas9	negative selection	5102700
19414594	19414616	17	-	27760321	HT29	viability after 19 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.2902996854532143	[143,112]	[195,220,125]	2	hSpCas9	negative selection	5102701
19413354	19413376	17	+	27760321	HT29	viability after 16 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.6163542641619205	[391,305]	[513,853,412]	7	hSpCas9	negative selection	5186162
19414465	19414487	17	-	27760321	HT29	viability after 16 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.03836946548622178	[358,279]	[553,178,334]	0	hSpCas9	negative selection	5186163
19414594	19414616	17	-	27760321	HT29	viability after 16 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	-0.1356462107805596	[143,112]	[130,119,141]	-1	hSpCas9	negative selection	5186164
19413354	19413376	17	+	27760321	HT29	viability after 13 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.520631357766643	[391,305]	[340,923,483]	6	hSpCas9	negative selection	5269625
19414465	19414487	17	-	27760321	HT29	viability after 13 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.10863127345202817	[358,279]	[362,423,249]	-1	hSpCas9	negative selection	5269626
19414594	19414616	17	-	27760321	HT29	viability after 13 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	-0.034201942178949896	[143,112]	[157,118,158]	0	hSpCas9	negative selection	5269627
19413354	19413376	17	+	27760321	HT29	viability after 10 days	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.3756290731799268	[391,305]	[436,663,596]	5	hSpCas9	negative selection	5353088
19414465	19414487	17	-	27760321	HT29	viability after 10 days	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	-0.15380781275811234	[358,279]	[304,289,475]	-2	hSpCas9	negative selection	5353089
19414594	19414616	17	-	27760321	HT29	viability after 10 days	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.3678223637872684	[143,112]	[203,162,251]	5	hSpCas9	negative selection	5353090
19413354	19413376	17	+	27760321	MOLM13	viability	CGCCAGGGGCATATGGATGTGG	RNF112	ENSG00000128482	0.6652722251703453	[465,391]	[430,340]	4	hSpCas9	negative selection	5436551
19414465	19414487	17	-	27760321	MOLM13	viability	TAATGCTTGCCCATCACCTCGG	RNF112	ENSG00000128482	0.6458238152157255	[450,358]	[94,576]	4	hSpCas9	negative selection	5436552
19414594	19414616	17	-	27760321	MOLM13	viability	GGATGAGTCACGAACTAAGAGG	RNF112	ENSG00000128482	0.6602446990107554	[210,143]	[50,245]	4	hSpCas9	negative selection	5436553
19411251	19411274	17	+	27661255	K562	viability	GACCGGGAGTCAGCTCCTCGGGG	RNF112	ENSG00000128482	0.5407780129476445	[282,318]	[368,331]	9	dCas9-KRAB	negative selection	5507746
19411550	19411573	17	+	27661255	K562	viability	GAGGGGTCCCTGGAAATCCAGGG	RNF112	ENSG00000128482	0.09001001415123411	[1287,1456]	[1294,1052]	3	dCas9-KRAB	negative selection	5507747
19411266	19411289	17	-	27661255	K562	viability	GTCGGGGGATGGTATCCCCGAGG	RNF112	ENSG00000128482	-0.11496841105334865	[287,262]	[229,180]	-4	dCas9-KRAB	negative selection	5507748
19411282	19411305	17	-	27661255	K562	viability	GTAGGTAGAAGGTGAGGTCGGGG	RNF112	ENSG00000128482	0.11263436430302359	[630,651]	[631,486]	4	dCas9-KRAB	negative selection	5507749
19411339	19411362	17	-	27661255	K562	viability	GAGACCTTCAACCAGAGGTAAGG	RNF112	ENSG00000128482	-0.044034418967709876	[383,476]	[382,288]	-2	dCas9-KRAB	negative selection	5507750
19413340	19413363	17	+	27260156	BXPC3	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.09621987426995202	[467]	[356,399,468,638]	-2	hSpCas9	negative selection	5567561
19413356	19413379	17	-	27260156	BXPC3	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.23865072192387315	[1821]	[1478,1554,1555,1910]	-5	hSpCas9	negative selection	5631814
19411629	19411652	17	+	27260156	BXPC3	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.21777180684389852	[269]	[325,233,327,442]	5	hSpCas9	negative selection	5631815
19413340	19413363	17	+	27260156	A673	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.13954235692875672	[467]	[553,675,657,574]	3	hSpCas9	negative selection	5688812
19413356	19413379	17	-	27260156	A673	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.0901150221658491	[1821]	[2387,1796,2012,2064]	-2	hSpCas9	negative selection	5753065
19411629	19411652	17	+	27260156	A673	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.2052830272090257	[269]	[484,406,321,287]	5	hSpCas9	negative selection	5753066
19413340	19413363	17	+	27260156	A375	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.11578601233048888	[467]	[662,543,665,498]	1	hSpCas9	negative selection	5810063
19413356	19413379	17	-	27260156	A375	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.18575329318472034	[1821]	[1846,2007,1570,2047]	-3	hSpCas9	negative selection	5874316
19411629	19411652	17	+	27260156	A375	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.48177783351802905	[269]	[388,571,387,429]	7	hSpCas9	negative selection	5874317
19413340	19413363	17	+	27260156	COLO741	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.06206944903950917	[467]	[628,607,633]	1	hSpCas9	negative selection	5931314
19413356	19413379	17	-	27260156	COLO741	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.03543187370786027	[1821]	[2621,2222,2330]	0	hSpCas9	negative selection	5995567
19411629	19411652	17	+	27260156	COLO741	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.49849009364559954	[269]	[339,623,484]	8	hSpCas9	negative selection	5995568
19413340	19413363	17	+	27260156	CAL120	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.4379886373464765	[467]	[513,1404,412]	6	hSpCas9	negative selection	6052565
19413356	19413379	17	-	27260156	CAL120	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.18435167222262772	[1821]	[2312,2066,1658]	-3	hSpCas9	negative selection	6116818
19411629	19411652	17	+	27260156	CAL120	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.22221437280022271	[269]	[491,267,429]	3	hSpCas9	negative selection	6116819
19413340	19413363	17	+	27260156	CADOES1	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.08316663636844429	[467]	[434,468,318,420]	-1	hSpCas9	negative selection	6173816
19413356	19413379	17	-	27260156	CADOES1	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.13650666005139533	[1821]	[1421,1501,1458,1792]	-2	hSpCas9	negative selection	6238069
19411629	19411652	17	+	27260156	CADOES1	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.39141252513035774	[269]	[304,267,349,396]	6	hSpCas9	negative selection	6238070
19413340	19413363	17	+	27260156	EWS502	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.13509319748654683	[467]	[659,392,502,615]	2	hSpCas9	negative selection	6295067
19413356	19413379	17	-	27260156	EWS502	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.134255437499343	[1821]	[1978,2178,2242,2075]	2	hSpCas9	negative selection	6359320
19411629	19411652	17	+	27260156	EWS502	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.4257172037392564	[269]	[405,321,414,392]	7	hSpCas9	negative selection	6359321
19413340	19413363	17	+	27260156	EW8	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.383606987129349	[467]	[489,578,445,470]	7	hSpCas9	negative selection	6416318
19413356	19413379	17	-	27260156	EW8	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.094749002122966	[1821]	[2050,1582,1445,1297]	1	hSpCas9	negative selection	6480571
19411629	19411652	17	+	27260156	EW8	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.254487369883714	[269]	[185,256,199,401]	4	hSpCas9	negative selection	6480572
19413340	19413363	17	+	27260156	CORL105	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.17749850702397477	[467]	[646,681,548,588]	3	hSpCas9	negative selection	6537569
19413356	19413379	17	-	27260156	CORL105	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.1254003700234121	[1821]	[1777,1606,2545,1982]	-2	hSpCas9	negative selection	6601822
19411629	19411652	17	+	27260156	CORL105	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.643062401303113	[269]	[606,374,671,354]	9	hSpCas9	negative selection	6601823
19413340	19413363	17	+	27260156	HS294T	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.039443697092496	[467]	[140,189,157,272]	0	hSpCas9	negative selection	6658820
19413356	19413379	17	-	27260156	HS294T	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.21488021144063296	[1821]	[796,584,776,1178]	3	hSpCas9	negative selection	6723073
19411629	19411652	17	+	27260156	HS294T	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.6037349480701633	[269]	[207,166,114,134]	7	hSpCas9	negative selection	6723074
19413340	19413363	17	+	27260156	HCC44	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.3609768448077602	[467]	[501,292,523,371]	-5	hSpCas9	negative selection	6780071
19413356	19413379	17	-	27260156	HCC44	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.3988423210881251	[1821]	[1532,1513,1939,1328]	-6	hSpCas9	negative selection	6844324
19411629	19411652	17	+	27260156	HCC44	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.37857268581627895	[269]	[451,358,499,304]	6	hSpCas9	negative selection	6844325
19413340	19413363	17	+	27260156	G402	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.41277486473884023	[467]	[654,279,518,290]	-5	hSpCas9	negative selection	6901322
19413356	19413379	17	-	27260156	G402	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.20884553120566962	[1821]	[2538,1658,2139,1445]	-3	hSpCas9	negative selection	6965575
19411629	19411652	17	+	27260156	G402	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.4933088278941988	[269]	[443,237,494,650]	6	hSpCas9	negative selection	6965576
19413340	19413363	17	+	27260156	L33	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.15843540809377724	[467]	[688,196,293,447]	3	hSpCas9	negative selection	7022573
19413356	19413379	17	-	27260156	L33	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.0192362539369475	[1821]	[1621,710,1089,2100]	0	hSpCas9	negative selection	7086826
19411629	19411652	17	+	27260156	L33	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	-0.010424563469585424	[269]	[209,133,164,273]	0	hSpCas9	negative selection	7086827
19413340	19413363	17	+	27260156	K562	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.2664214787365677	[467]	[316,274,316,451]	-3	hSpCas9	negative selection	7143824
19413356	19413379	17	-	27260156	K562	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.08826216555043631	[1821]	[1851,1956,1143,1210]	-1	hSpCas9	negative selection	7208077
19411629	19411652	17	+	27260156	K562	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.9027021391308285	[269]	[127,686,472,483]	9	hSpCas9	negative selection	7208078
19413340	19413363	17	+	27260156	HT29	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.1037634574551279	[467]	[720,637,520,575]	2	hSpCas9	negative selection	7265075
19413356	19413379	17	-	27260156	HT29	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.024733896611766282	[1821]	[2204,2273,2142,2091]	0	hSpCas9	negative selection	7329328
19411629	19411652	17	+	27260156	HT29	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.1011289794677781	[269]	[422,462,266,276]	2	hSpCas9	negative selection	7329329
19413340	19413363	17	+	27260156	MHHES1	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.0344187106407082	[467]	[407,591,533,589]	0	hSpCas9	negative selection	7386326
19413356	19413379	17	-	27260156	MHHES1	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.17668690900871864	[1821]	[2130,2171,1774,1330]	-3	hSpCas9	negative selection	7450579
19411629	19411652	17	+	27260156	MHHES1	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.5141508340823149	[269]	[413,289,623,392]	8	hSpCas9	negative selection	7450580
19413340	19413363	17	+	27260156	MEWO	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.13834154149627306	[467]	[475,291,440]	-3	hSpCas9	negative selection	7507577
19413356	19413379	17	-	27260156	MEWO	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.023118359394461496	[1821]	[1862,1599,1758]	0	hSpCas9	negative selection	7571830
19411629	19411652	17	+	27260156	MEWO	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.09724368794410143	[269]	[331,178,311]	2	hSpCas9	negative selection	7571831
19413340	19413363	17	+	27260156	LNCAPCLONEFGC	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.01835794697200795	[467]	[501,351,510,367]	0	hSpCas9	negative selection	7628828
19413356	19413379	17	-	27260156	LNCAPCLONEFGC	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.08066902209939864	[1821]	[1690,1440,1754,1388]	-1	hSpCas9	negative selection	7693081
19411629	19411652	17	+	27260156	LNCAPCLONEFGC	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.5196113674999437	[269]	[266,407,376,351]	7	hSpCas9	negative selection	7693082
19413340	19413363	17	+	27260156	PANC0327	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.5486863046979069	[467]	[347,159,299,349]	-7	hSpCas9	negative selection	7750079
19413356	19413379	17	-	27260156	PANC0327	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.08157708489023818	[1821]	[2026,1922,1017,1138]	-1	hSpCas9	negative selection	7814332
19411629	19411652	17	+	27260156	PANC0327	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.3408777469669051	[269]	[250,338,261,353]	5	hSpCas9	negative selection	7814333
19413340	19413363	17	+	27260156	NCIH2009	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.007969296254389299	[467]	[864,602,524]	0	hSpCas9	negative selection	7871330
19413356	19413379	17	-	27260156	NCIH2009	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.0454417973526815	[1821]	[2841,2640,2435]	0	hSpCas9	negative selection	7935583
19411629	19411652	17	+	27260156	NCIH2009	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.5758817615575422	[269]	[597,506,588]	7	hSpCas9	negative selection	7935584
19413340	19413363	17	+	27260156	NCIH1373	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.9898395492088249	[467]	[194,326,378,32]	-7	hSpCas9	negative selection	7992581
19413356	19413379	17	-	27260156	NCIH1373	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.33403516277150924	[1821]	[1808,1400,1555,464]	-3	hSpCas9	negative selection	8056834
19411629	19411652	17	+	27260156	NCIH1373	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.6896513545801348	[269]	[681,300,609,104]	7	hSpCas9	negative selection	8056835
19413340	19413363	17	+	27260156	PATU8902	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.6144469192099382	[467]	[388,686,325,310]	-5	hSpCas9	negative selection	8113832
19413356	19413379	17	-	27260156	PATU8902	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.26088432435808606	[1821]	[1686,2116,1571,3375]	-3	hSpCas9	negative selection	8178085
19411629	19411652	17	+	27260156	PATU8902	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.49978718549091977	[269]	[743,728,136,623]	5	hSpCas9	negative selection	8178086
19413340	19413363	17	+	27260156	PANC1	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.5839849185762472	[467]	[207,236,358,260]	-7	hSpCas9	negative selection	8235083
19413356	19413379	17	-	27260156	PANC1	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.23099437779617804	[1821]	[1404,1498,1291,1173]	-4	hSpCas9	negative selection	8299336
19411629	19411652	17	+	27260156	PANC1	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.22410635792685107	[269]	[325,307,307,161]	3	hSpCas9	negative selection	8299337
19413340	19413363	17	+	27260156	PANC0813	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.38567221020166204	[467]	[761,983,580,556]	6	hSpCas9	negative selection	8356334
19413356	19413379	17	-	27260156	PANC0813	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.15155053638282467	[1821]	[2450,2607,2086,2364]	2	hSpCas9	negative selection	8420587
19411629	19411652	17	+	27260156	PANC0813	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.4617516317068339	[269]	[317,306,405,689]	7	hSpCas9	negative selection	8420588
19413340	19413363	17	+	27260156	RDES	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.09179509693661571	[467]	[588,369,455,592]	-1	hSpCas9	negative selection	8477585
19413356	19413379	17	-	27260156	RDES	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.035590765513474176	[1821]	[1717,1805,2189,2581]	0	hSpCas9	negative selection	8541838
19411629	19411652	17	+	27260156	RDES	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.2999311103217043	[269]	[368,399,359,387]	5	hSpCas9	negative selection	8541839
19413340	19413363	17	+	27260156	PC3	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.17656421434244998	[467]	[367,347,656,337]	-4	hSpCas9	negative selection	8598836
19413356	19413379	17	-	27260156	PC3	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.15170356558794174	[1821]	[1113,1630,2412,1744]	-3	hSpCas9	negative selection	8663089
19411629	19411652	17	+	27260156	PC3	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.3077689655297328	[269]	[286,286,607,232]	6	hSpCas9	negative selection	8663090
19413340	19413363	17	+	27260156	PATU8988T	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.010311411645840629	[467]	[337,315,435,741]	0	hSpCas9	negative selection	8720087
19413356	19413379	17	-	27260156	PATU8988T	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.006745151965253271	[1821]	[1718,1942,1601,1834]	0	hSpCas9	negative selection	8784340
19411629	19411652	17	+	27260156	PATU8988T	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.8855869052259508	[269]	[222,437,617,656]	9	hSpCas9	negative selection	8784341
19413340	19413363	17	+	27260156	T47D	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.46110648802883963	[467]	[422,290,461,416]	-7	hSpCas9	negative selection	8841338
19413356	19413379	17	-	27260156	T47D	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.2542171551383696	[1821]	[1998,1617,1732,1783]	-5	hSpCas9	negative selection	8905591
19411629	19411652	17	+	27260156	T47D	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.36225006035994145	[269]	[420,471,370,345]	7	hSpCas9	negative selection	8905592
19413340	19413363	17	+	27260156	SU8686	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.2764189635860722	[467]	[557,506,520,683]	5	hSpCas9	negative selection	8962589
19413356	19413379	17	-	27260156	SU8686	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.037150338817110606	[1821]	[1525,1600,2129,1842]	0	hSpCas9	negative selection	9026842
19411629	19411652	17	+	27260156	SU8686	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.5637834479746644	[269]	[455,283,384,474]	8	hSpCas9	negative selection	9026843
19413340	19413363	17	+	27260156	SKES1	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	0.21305576148646102	[467]	[672,438,634,429]	4	hSpCas9	negative selection	9083840
19413356	19413379	17	-	27260156	SKES1	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.34776775184603204	[1821]	[1425,1553,1336,1399]	-6	hSpCas9	negative selection	9148093
19411629	19411652	17	+	27260156	SKES1	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.22665555003178195	[269]	[300,325,432,207]	5	hSpCas9	negative selection	9148094
19413340	19413363	17	+	27260156	TOV112D	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.14818640294544957	[467]	[331,599,368,425]	-3	hSpCas9	negative selection	9205091
19413356	19413379	17	-	27260156	TOV112D	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.1952480959312799	[1821]	[1988,1747,1368,1344]	-4	hSpCas9	negative selection	9269344
19411629	19411652	17	+	27260156	TOV112D	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.3935860718755357	[269]	[257,579,292,336]	7	hSpCas9	negative selection	9269345
19413340	19413363	17	+	27260156	TC71	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.06162787279055647	[467]	[414,436,514,560]	-1	hSpCas9	negative selection	9326342
19413356	19413379	17	-	27260156	TC71	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	-0.1321042456078192	[1821]	[1766,1769,1818,1770]	-3	hSpCas9	negative selection	9390595
19411629	19411652	17	+	27260156	TC71	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.2003799230720439	[269]	[306,302,395,321]	5	hSpCas9	negative selection	9390596
19413340	19413363	17	+	27260156	TC32	viability	GGCGCCAATGGCCTCGCCAGGGG	RNF112	ENSG00000128482	-0.09944288965795722	[467]	[299,340,491,546]	-2	hSpCas9	negative selection	9447593
19413356	19413379	17	-	27260156	TC32	viability	GCTCCACATCCATATGCCCCTGG	RNF112	ENSG00000128482	0.05896008814888054	[1821]	[1550,1670,2198,1741]	1	hSpCas9	negative selection	9511846
19411629	19411652	17	+	27260156	TC32	viability	GGAGAGAAAACAGAGCTTCATGG	RNF112	ENSG00000128482	0.31225787152908857	[269]	[276,224,413,385]	5	hSpCas9	negative selection	9511847
19413580	19413603	17	+	27869803	HPAFII	viability after 27 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.5755216359185703	[326]	[146,88,NaN]	-4	hSpCas9	negative selection	9559501
19414112	19414135	17	+	27869803	HPAFII	viability after 27 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.9452865589439362	[299]	[100,65,NaN]	-6	hSpCas9	negative selection	9559502
19414472	19414495	17	+	27869803	HPAFII	viability after 27 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-1.0687470064135371	[106]	[34,19,NaN]	-6	hSpCas9	negative selection	9559503
19414848	19414871	17	+	27869803	HPAFII	viability after 27 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.22247377402619928	[94]	[66,50,NaN]	1	hSpCas9	negative selection	9559504
19413580	19413603	17	+	27869803	HPAFII	viability after 15 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.30823088966267387	[326]	[555,359,NaN]	3	hSpCas9	negative selection	9641950
19414112	19414135	17	+	27869803	HPAFII	viability after 15 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.40837912400782267	[299]	[237,245,NaN]	-4	hSpCas9	negative selection	9641951
19414472	19414495	17	+	27869803	HPAFII	viability after 15 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.11161746598128364	[106]	[119,97,NaN]	-1	hSpCas9	negative selection	9641952
19414848	19414871	17	+	27869803	HPAFII	viability after 15 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.04922496978274715	[94]	[207,41,NaN]	0	hSpCas9	negative selection	9641953
19413580	19413603	17	+	27869803	ASPC1	viability after 36 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.35416744049710147	[942]	[290,550,403]	3	hSpCas9	negative selection	9724399
19414112	19414135	17	+	27869803	ASPC1	viability after 36 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.02756928450104787	[712]	[409,207,153]	0	hSpCas9	negative selection	9724400
19414472	19414495	17	+	27869803	ASPC1	viability after 36 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	0.3066085927082338	[206]	[75,39,136]	3	hSpCas9	negative selection	9724401
19414848	19414871	17	+	27869803	ASPC1	viability after 36 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.06185691412672223	[399]	[180,197,77]	0	hSpCas9	negative selection	9724402
19413580	19413603	17	+	27869803	PATU8988S	viability after 35 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.43394156592744415	[914]	[425,569,NaN]	5	hSpCas9	negative selection	9806848
19414112	19414135	17	+	27869803	PATU8988S	viability after 35 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.35375269077898025	[504]	[218,300,NaN]	4	hSpCas9	negative selection	9806849
19414472	19414495	17	+	27869803	PATU8988S	viability after 35 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.232009354961348	[200]	[36,100,NaN]	-2	hSpCas9	negative selection	9806850
19414848	19414871	17	+	27869803	PATU8988S	viability after 35 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.08274813248258572	[371]	[128,153,NaN]	-1	hSpCas9	negative selection	9806851
19413580	19413603	17	+	27869803	PATU8988S	viability after 31 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	0.1960966441276153	[914]	[274,599,NaN]	2	hSpCas9	negative selection	9889297
19414112	19414135	17	+	27869803	PATU8988S	viability after 31 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	0.17003423251103472	[504]	[193,267,NaN]	2	hSpCas9	negative selection	9889298
19414472	19414495	17	+	27869803	PATU8988S	viability after 31 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.7421459229836209	[200]	[28,71,NaN]	-7	hSpCas9	negative selection	9889299
19414848	19414871	17	+	27869803	PATU8988S	viability after 31 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.3607584842510789	[371]	[89,147,NaN]	-4	hSpCas9	negative selection	9889300
19413580	19413603	17	+	27869803	HPAFII	viability after 35 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.27861448164922514	[326]	[135,136,NaN]	-2	hSpCas9	negative selection	9971746
19414112	19414135	17	+	27869803	HPAFII	viability after 35 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.29216598033805613	[299]	[68,185,NaN]	-2	hSpCas9	negative selection	9971747
19414472	19414495	17	+	27869803	HPAFII	viability after 35 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-3.339359984523785	[106]	[2,7,NaN]	-8	hSpCas9	negative selection	9971748
19414848	19414871	17	+	27869803	HPAFII	viability after 35 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-1.1437097368777043	[94]	[25,16,NaN]	-6	hSpCas9	negative selection	9971749
19413580	19413603	17	+	27869803	HPAFII	viability after 31 days	GCGGTGTTCCTGGTGGACACAGG	RNF112	ENSG00000128482	-0.08753201863130533	[326]	[143,203,NaN]	0	hSpCas9	negative selection	10054195
19414112	19414135	17	+	27869803	HPAFII	viability after 31 days	GGAGCTGAAGGATACAGACCTGG	RNF112	ENSG00000128482	-0.41343179350732795	[299]	[90,164,NaN]	-3	hSpCas9	negative selection	10054196
19414472	19414495	17	+	27869803	HPAFII	viability after 31 days	GATGGGCAAGCATTATGGGATGG	RNF112	ENSG00000128482	-0.9642414205604732	[106]	[36,23,NaN]	-6	hSpCas9	negative selection	10054197
19414848	19414871	17	+	27869803	HPAFII	viability after 31 days	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-1.3649255460437277	[94]	[13,27,NaN]	-7	hSpCas9	negative selection	10054198
19411419	19411442	17	-	28162770	P31FUJ	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.371408180900056	[272]	[414]	4	hSpCas9	negative selection	10225987
19413582	19413605	17	+	28162770	P31FUJ	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-2.238340387955809	[260]	[64]	-8	hSpCas9	negative selection	10225988
19414848	19414871	17	+	28162770	P31FUJ	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6821096057779688	[141]	[103]	-5	hSpCas9	negative selection	10225989
19415186	19415209	17	+	28162770	P31FUJ	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	1.8826750130055574	[77]	[337]	9	hSpCas9	negative selection	10225990
19411406	19411429	17	-	28162770	P31FUJ	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.2477527057886727	[338]	[472]	2	hSpCas9	negative selection	10225991
19411419	19411442	17	-	28162770	TF1	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10395353
19413582	19413605	17	+	28162770	TF1	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10395354
19414848	19414871	17	+	28162770	TF1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10395355
19415186	19415209	17	+	28162770	TF1	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10395356
19411406	19411429	17	-	28162770	TF1	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10395357
19411419	19411442	17	-	28162770	SKM1	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	-0.4036890667103007	[109]	[146]	-3	hSpCas9	negative selection	10564719
19413582	19413605	17	+	28162770	SKM1	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.2225396276057343	[98]	[74]	-7	hSpCas9	negative selection	10564720
19414848	19414871	17	+	28162770	SKM1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-2.069929211465591	[37]	[15]	-8	hSpCas9	negative selection	10564721
19415186	19415209	17	+	28162770	SKM1	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-0.5589672921882118	[9]	[11]	-4	hSpCas9	negative selection	10564722
19411406	19411429	17	-	28162770	SKM1	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.43383720640758444	[66]	[159]	4	hSpCas9	negative selection	10564723
19411419	19411442	17	-	28162770	SKM1	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	-0.4036890667103007	[109]	[146]	-3	hSpCas9	negative selection	10734085
19413582	19413605	17	+	28162770	SKM1	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.2225396276057343	[98]	[74]	-7	hSpCas9	negative selection	10734086
19414848	19414871	17	+	28162770	SKM1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-2.069929211465591	[37]	[15]	-8	hSpCas9	negative selection	10734087
19415186	19415209	17	+	28162770	SKM1	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-0.5589672921882118	[9]	[11]	-4	hSpCas9	negative selection	10734088
19411406	19411429	17	-	28162770	SKM1	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.43383720640758444	[66]	[159]	4	hSpCas9	negative selection	10734089
19411419	19411442	17	-	28162770	PL21	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.7916036811524316	[368]	[277]	6	hSpCas9	negative selection	10903451
19413582	19413605	17	+	28162770	PL21	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	0.5532493646249621	[237]	[151]	5	hSpCas9	negative selection	10903452
19414848	19414871	17	+	28162770	PL21	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.3770173765733995	[91]	[51]	3	hSpCas9	negative selection	10903453
19415186	19415209	17	+	28162770	PL21	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-0.3023607260398631	[33]	[11]	-2	hSpCas9	negative selection	10903454
19411406	19411429	17	-	28162770	PL21	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.48338724121262266	[188]	[114]	4	hSpCas9	negative selection	10903455
19411419	19411442	17	-	28162770	P31FUJ	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.371408180900056	[272]	[414]	4	hSpCas9	negative selection	11072817
19413582	19413605	17	+	28162770	P31FUJ	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-2.238340387955809	[260]	[64]	-8	hSpCas9	negative selection	11072818
19414848	19414871	17	+	28162770	P31FUJ	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.6821096057779688	[141]	[103]	-5	hSpCas9	negative selection	11072819
19415186	19415209	17	+	28162770	P31FUJ	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	1.8826750130055574	[77]	[337]	9	hSpCas9	negative selection	11072820
19411406	19411429	17	-	28162770	P31FUJ	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.2477527057886727	[338]	[472]	2	hSpCas9	negative selection	11072821
19411419	19411442	17	-	28162770	OCIAML5	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.9687401506622151	[121]	[430]	8	hSpCas9	negative selection	11242183
19413582	19413605	17	+	28162770	OCIAML5	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.1562199640233832	[120]	[97]	-6	hSpCas9	negative selection	11242184
19414848	19414871	17	+	28162770	OCIAML5	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.25645788591417207	[63]	[137]	2	hSpCas9	negative selection	11242185
19415186	19415209	17	+	28162770	OCIAML5	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	0.12284244817317247	[28]	[56]	1	hSpCas9	negative selection	11242186
19411406	19411429	17	-	28162770	OCIAML5	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.011431429231140822	[143]	[261]	0	hSpCas9	negative selection	11242187
19411419	19411442	17	-	28162770	EOL1	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.18834169047314098	[632]	[379]	1	hSpCas9	negative selection	11411549
19413582	19413605	17	+	28162770	EOL1	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.0348102439321194	[524]	[134]	-6	hSpCas9	negative selection	11411550
19414848	19414871	17	+	28162770	EOL1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.43802230781417384	[143]	[55]	-3	hSpCas9	negative selection	11411551
19415186	19415209	17	+	28162770	EOL1	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	0.5588982992538543	[66]	[51]	5	hSpCas9	negative selection	11411552
19411406	19411429	17	-	28162770	EOL1	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	-0.43644988799542017	[261]	[101]	-3	hSpCas9	negative selection	11411553
19411419	19411442	17	-	28162770	MOLM13	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.8718595769205857	[457]	[605]	6	hSpCas9	negative selection	11580915
19413582	19413605	17	+	28162770	MOLM13	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.224486061597557	[445]	[137]	-6	hSpCas9	negative selection	11580916
19414848	19414871	17	+	28162770	MOLM13	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.8079648231422005	[157]	[199]	6	hSpCas9	negative selection	11580917
19415186	19415209	17	+	28162770	MOLM13	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-1.2101825235680592	[47]	[14]	-6	hSpCas9	negative selection	11580918
19411406	19411429	17	-	28162770	MOLM13	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	-0.673771767679012	[277]	[125]	-4	hSpCas9	negative selection	11580919
19411419	19411442	17	-	28162770	HEL	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.42538200056120756	[428]	[368]	3	hSpCas9	negative selection	11750281
19413582	19413605	17	+	28162770	HEL	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.0105296821117078	[345]	[109]	-6	hSpCas9	negative selection	11750282
19414848	19414871	17	+	28162770	HEL	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.9958485821359988	[118]	[151]	8	hSpCas9	negative selection	11750283
19415186	19415209	17	+	28162770	HEL	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-2.209703979585785	[64]	[8]	-8	hSpCas9	negative selection	11750284
19411406	19411429	17	-	28162770	HEL	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.8252833199737828	[214]	[243]	7	hSpCas9	negative selection	11750285
19411419	19411442	17	-	28162770	MV411	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.465268086765966	[361]	[420]	4	hSpCas9	negative selection	11919647
19413582	19413605	17	+	28162770	MV411	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-0.2204518307618034	[277]	[200]	-2	hSpCas9	negative selection	11919648
19414848	19414871	17	+	28162770	MV411	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.7460397667007505	[108]	[153]	6	hSpCas9	negative selection	11919649
19415186	19415209	17	+	28162770	MV411	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-0.5756846871331454	[45]	[25]	-4	hSpCas9	negative selection	11919650
19411406	19411429	17	-	28162770	MV411	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	-0.1975372326501724	[210]	[154]	-1	hSpCas9	negative selection	11919651
19411419	19411442	17	-	28162770	MONOMAC1	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.4826300776084639	[225]	[361]	5	hSpCas9	negative selection	12089013
19413582	19413605	17	+	28162770	MONOMAC1	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-0.16497563782725522	[177]	[181]	-1	hSpCas9	negative selection	12089014
19414848	19414871	17	+	28162770	MONOMAC1	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	0.21260739344907187	[66]	[88]	2	hSpCas9	negative selection	12089015
19415186	19415209	17	+	28162770	MONOMAC1	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-0.4194292683960019	[27]	[23]	-4	hSpCas9	negative selection	12089016
19411406	19411429	17	-	28162770	MONOMAC1	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.7583730019163759	[114]	[222]	7	hSpCas9	negative selection	12089017
19411419	19411442	17	-	28162770	OCIAML2	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	0.9099741769728087	[52]	[551]	8	hSpCas9	negative selection	12258379
19413582	19413605	17	+	28162770	OCIAML2	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-0.7722855251032624	[52]	[171]	-5	hSpCas9	negative selection	12258380
19414848	19414871	17	+	28162770	OCIAML2	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	-0.3775204208506797	[14]	[63]	-3	hSpCas9	negative selection	12258381
19415186	19415209	17	+	28162770	OCIAML2	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	-1.5377440211006979	[10]	[20]	-7	hSpCas9	negative selection	12258382
19411406	19411429	17	-	28162770	OCIAML2	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.4314437540685816	[39]	[298]	4	hSpCas9	negative selection	12258383
19411419	19411442	17	-	28162770	OCIAML3	viability	AAAGGAAGTGACTGACAAGGCGG	RNF112	ENSG00000128482	-0.06992738175002966	[120]	[347]	0	hSpCas9	negative selection	12427745
19413582	19413605	17	+	28162770	OCIAML3	viability	GGTGTTCCTGGTGGACACAGGGG	RNF112	ENSG00000128482	-1.5940076403241632	[84]	[84]	-8	hSpCas9	negative selection	12427746
19414848	19414871	17	+	28162770	OCIAML3	viability	GGGAGGCGGCGGATGAACCAAGG	RNF112	ENSG00000128482	1.1129453847756035	[33]	[221]	8	hSpCas9	negative selection	12427747
19415186	19415209	17	+	28162770	OCIAML3	viability	GCAGCTAGCTCAGGAAATCAAGG	RNF112	ENSG00000128482	0.16087986183930547	[15]	[53]	1	hSpCas9	negative selection	12427748
19411406	19411429	17	-	28162770	OCIAML3	viability	GACAAGGCGGGCCTTGGCATGGG	RNF112	ENSG00000128482	0.4952596977729241	[46]	[199]	4	hSpCas9	negative selection	12427749