Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6197
• Symbol: RPS6KA3
• Description: ribosomal protein S6 kinase A3

DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KA3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
20266611	20266634	X	-	26472758	Jiyoye	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	1.0046288264102263	[114]	[173]	6	hSpCas9	negative selection	140242
20195098	20195121	X	-	26472758	Jiyoye	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.6310209420550768	[420]	[204]	-4	hSpCas9	negative selection	140243
20234775	20234798	X	-	26472758	Jiyoye	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	2.2816444994220144	[35]	[131]	9	hSpCas9	negative selection	140244
20161675	20161698	X	-	26472758	Jiyoye	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.18478296016942564	[237]	[203]	1	hSpCas9	negative selection	140245
20156108	20156131	X	-	26472758	Jiyoye	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.3476743697572118	[296]	[284]	2	hSpCas9	negative selection	140246
20266563	20266586	X	-	26472758	Jiyoye	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	-0.06781427719015132	[302]	[217]	0	hSpCas9	negative selection	140247
20172782	20172805	X	+	26472758	Jiyoye	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-1.2544084008181953	[173]	[54]	-7	hSpCas9	negative selection	140248
20156197	20156220	X	+	26472758	Jiyoye	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.085247286618511	[264]	[211]	0	hSpCas9	negative selection	140249
20266587	20266610	X	-	26472758	Jiyoye	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	-0.09532495902330984	[33]	[23]	0	hSpCas9	negative selection	140250
20204011	20204034	X	+	26472758	Jiyoye	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	1.227950819325799	[106]	[188]	7	hSpCas9	negative selection	140251
20266611	20266634	X	-	26472758	KBM7	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	1.3917824286435811	[240,186]	[291,234]	9	hSpCas9	negative selection	331360
20195098	20195121	X	-	26472758	KBM7	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.018554168057141274	[1181,1141]	[457,641]	0	hSpCas9	negative selection	331361
20234775	20234798	X	-	26472758	KBM7	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.4214362910494961	[360,301]	[285,137]	4	hSpCas9	negative selection	331362
20161675	20161698	X	-	26472758	KBM7	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.09258225253479196	[727,458]	[242,335]	0	hSpCas9	negative selection	331363
20156108	20156131	X	-	26472758	KBM7	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.3823160483727073	[1435,1311]	[855,829]	4	hSpCas9	negative selection	331364
20266563	20266586	X	-	26472758	KBM7	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.3266694420790508	[1369,836]	[603,667]	3	hSpCas9	negative selection	331365
20172782	20172805	X	+	26472758	KBM7	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-0.2417604873580469	[568,324]	[66,268]	-2	hSpCas9	negative selection	331366
20156197	20156220	X	+	26472758	KBM7	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.005960892605620272	[1302,1336]	[436,796]	0	hSpCas9	negative selection	331367
20266587	20266610	X	-	26472758	KBM7	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.83831918823539	[126,60]	[112,43]	8	hSpCas9	negative selection	331368
20204011	20204034	X	+	26472758	KBM7	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.3936173371691085	[1016,942]	[493,705]	4	hSpCas9	negative selection	331369
20266611	20266634	X	-	26472758	Raji	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	-0.37374315436301664	[133]	[23]	-3	hSpCas9	negative selection	522478
20195098	20195121	X	-	26472758	Raji	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.3613859478430339	[619]	[111]	-3	hSpCas9	negative selection	522479
20234775	20234798	X	-	26472758	Raji	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	1.6139749725418835	[144]	[102]	9	hSpCas9	negative selection	522480
20161675	20161698	X	-	26472758	Raji	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.658398704171418	[171]	[62]	6	hSpCas9	negative selection	522481
20156108	20156131	X	-	26472758	Raji	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.6862458365583379	[631]	[235]	6	hSpCas9	negative selection	522482
20266563	20266586	X	-	26472758	Raji	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.7925101980201874	[305]	[122]	7	hSpCas9	negative selection	522483
20172782	20172805	X	+	26472758	Raji	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	1.1498188016939963	[133]	[68]	8	hSpCas9	negative selection	522484
20156197	20156220	X	+	26472758	Raji	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.9323522168736105	[772]	[93]	-6	hSpCas9	negative selection	522485
20266587	20266610	X	-	26472758	Raji	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.18681800286800443	[52]	[13]	1	hSpCas9	negative selection	522486
20204011	20204034	X	+	26472758	Raji	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.3983119473430551	[460]	[140]	4	hSpCas9	negative selection	522487
20266611	20266634	X	-	26472758	K562	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	1.2556024661591225	[256]	[517]	9	hSpCas9	negative selection	713596
20195098	20195121	X	-	26472758	K562	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.3162560473212934	[900]	[946]	2	hSpCas9	negative selection	713597
20234775	20234798	X	-	26472758	K562	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.27179516659775194	[260]	[265]	2	hSpCas9	negative selection	713598
20161675	20161698	X	-	26472758	K562	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.9380382919070658	[472]	[764]	7	hSpCas9	negative selection	713599
20156108	20156131	X	-	26472758	K562	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.3584388244283385	[1142]	[1236]	3	hSpCas9	negative selection	713600
20266563	20266586	X	-	26472758	K562	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.48511680352214004	[715]	[845]	4	hSpCas9	negative selection	713601
20172782	20172805	X	+	26472758	K562	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-0.36370149404196184	[313]	[205]	-2	hSpCas9	negative selection	713602
20156197	20156220	X	+	26472758	K562	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.34437563464573606	[1130]	[751]	-2	hSpCas9	negative selection	713603
20266587	20266610	X	-	26472758	K562	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.5339253448614318	[62]	[76]	4	hSpCas9	negative selection	713604
20204011	20204034	X	+	26472758	K562	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	-0.10458890127720011	[846]	[664]	0	hSpCas9	negative selection	713605
20155433	20155456	X	+	26627737	DLD1	viability	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.7168233022089675	[677]	[349,381,318]	7	hSpCas9	negative selection	845316
20156163	20156186	X	-	26627737	DLD1	viability	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	0.14233993551649204	[158]	[7,52,96]	1	hSpCas9	negative selection	845317
20161721	20161744	X	-	26627737	DLD1	viability	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.1734480240348797	[677]	[149,142,257]	-2	hSpCas9	negative selection	845318
20167622	20167645	X	+	26627737	DLD1	viability	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.5054265246683357	[402]	[58,156,57]	-5	hSpCas9	negative selection	845319
20266559	20266582	X	+	26627737	DLD1	viability	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.7676420125481893	[201]	[175,97,55]	7	hSpCas9	negative selection	845320
20266593	20266616	X	-	26627737	DLD1	viability	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.49558838540637906	[360]	[84,208,181]	5	hSpCas9	negative selection	845321
20155433	20155456	X	+	26627737	GBM cells	viability after 5 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.31945148161438	[476]	[195,213]	-5	hSpCas9	negative selection	927631
20156163	20156186	X	-	26627737	GBM cells	viability after 5 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-0.7976939816643798	[46]	[16,11]	-8	hSpCas9	negative selection	927632
20161721	20161744	X	-	26627737	GBM cells	viability after 5 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.24528085146320922	[388]	[183,167]	-4	hSpCas9	negative selection	927633
20167622	20167645	X	+	26627737	GBM cells	viability after 5 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.22884167231268726	[235]	[110,104]	-4	hSpCas9	negative selection	927634
20266559	20266582	X	+	26627737	GBM cells	viability after 5 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.10327237339187201	[183]	[118,92]	1	hSpCas9	negative selection	927635
20266593	20266616	X	-	26627737	GBM cells	viability after 5 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.7245836943233721	[122]	[74,142]	8	hSpCas9	negative selection	927636
20155433	20155456	X	+	26627737	GBM cells	viability after 13 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.79500837206287	[476]	[125,167]	-7	hSpCas9	negative selection	1009946
20156163	20156186	X	-	26627737	GBM cells	viability after 13 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-0.3253203417128048	[46]	[37,5]	-4	hSpCas9	negative selection	1009947
20161721	20161744	X	-	26627737	GBM cells	viability after 13 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.09302407240293975	[388]	[241,161]	-1	hSpCas9	negative selection	1009948
20167622	20167645	X	+	26627737	GBM cells	viability after 13 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.2817552485021036	[235]	[149,68]	-3	hSpCas9	negative selection	1009949
20266559	20266582	X	+	26627737	GBM cells	viability after 13 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.07887968400788659	[183]	[104,85]	-1	hSpCas9	negative selection	1009950
20266593	20266616	X	-	26627737	GBM cells	viability after 13 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	1.0376981301567307	[122]	[152,123]	9	hSpCas9	negative selection	1009951
20155433	20155456	X	+	26627737	GBM cells	viability after 21 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-1.0413503663414294	[476]	[127,123]	-7	hSpCas9	negative selection	1092261
20156163	20156186	X	-	26627737	GBM cells	viability after 21 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-1.4298067170733635	[46]	[9,8]	-8	hSpCas9	negative selection	1092262
20161721	20161744	X	-	26627737	GBM cells	viability after 21 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.08338918109141547	[388]	[211,187]	0	hSpCas9	negative selection	1092263
20167622	20167645	X	+	26627737	GBM cells	viability after 21 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.9215626195885654	[235]	[74,60]	-7	hSpCas9	negative selection	1092264
20266559	20266582	X	+	26627737	GBM cells	viability after 21 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.2082815908968732	[183]	[103,125]	2	hSpCas9	negative selection	1092265
20266593	20266616	X	-	26627737	GBM cells	viability after 21 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.721408254033466	[122]	[105,113]	7	hSpCas9	negative selection	1092266
20155433	20155456	X	+	26627737	RPE1	viability after 9 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.16925555882491594	[1284]	[238,510]	-1	hSpCas9	negative selection	1174576
20156163	20156186	X	-	26627737	RPE1	viability after 9 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	3.345878373225325	[0]	[0,5]	9	hSpCas9	negative selection	1174577
20161721	20161744	X	-	26627737	RPE1	viability after 9 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.22267992468307277	[802]	[157,467]	1	hSpCas9	negative selection	1174578
20167622	20167645	X	+	26627737	RPE1	viability after 9 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.19441839088327784	[422]	[106,126]	-1	hSpCas9	negative selection	1174579
20266559	20266582	X	+	26627737	RPE1	viability after 9 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-4.410967159437602	[1180]	[19,13]	-9	hSpCas9	negative selection	1174580
20266593	20266616	X	-	26627737	RPE1	viability after 9 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	1.100225077893168	[473]	[232,427]	6	hSpCas9	negative selection	1174581
20155433	20155456	X	+	26627737	RPE1	viability after 12 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.11209168162251637	[1284]	[248,393]	0	hSpCas9	negative selection	1256891
20156163	20156186	X	-	26627737	RPE1	viability after 12 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	4.321417246405809	[0]	[0,9]	9	hSpCas9	negative selection	1256892
20161721	20161744	X	-	26627737	RPE1	viability after 12 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.45072756752147347	[802]	[170,425]	3	hSpCas9	negative selection	1256893
20167622	20167645	X	+	26627737	RPE1	viability after 12 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.9882989370494956	[422]	[49,64]	-6	hSpCas9	negative selection	1256894
20266559	20266582	X	+	26627737	RPE1	viability after 12 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-2.628393219927839	[1180]	[27,75]	-9	hSpCas9	negative selection	1256895
20266593	20266616	X	-	26627737	RPE1	viability after 12 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	1.0940730869912965	[473]	[232,312]	6	hSpCas9	negative selection	1256896
20155433	20155456	X	+	26627737	RPE1	viability after 15 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.1068860079233438	[1284]	[278,393]	0	hSpCas9	negative selection	1339206
20156163	20156186	X	-	26627737	RPE1	viability after 15 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	4.302388314780586	[0]	[0,9]	9	hSpCas9	negative selection	1339207
20161721	20161744	X	-	26627737	RPE1	viability after 15 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.3721095296479875	[802]	[153,428]	2	hSpCas9	negative selection	1339208
20167622	20167645	X	+	26627737	RPE1	viability after 15 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-1.3537426244574768	[422]	[56,36]	-7	hSpCas9	negative selection	1339209
20266559	20266582	X	+	26627737	RPE1	viability after 15 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-2.5861628204332496	[1180]	[19,89]	-8	hSpCas9	negative selection	1339210
20266593	20266616	X	-	26627737	RPE1	viability after 15 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.8279193855561855	[473]	[208,265]	5	hSpCas9	negative selection	1339211
20155433	20155456	X	+	26627737	RPE1	viability after 18 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.29507469463409497	[1284]	[322,534]	2	hSpCas9	negative selection	1421521
20156163	20156186	X	-	26627737	RPE1	viability after 18 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.49049716628092	[0]	[1,0]	9	hSpCas9	negative selection	1421522
20161721	20161744	X	-	26627737	RPE1	viability after 18 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.33093845160648483	[802]	[201,347]	2	hSpCas9	negative selection	1421523
20167622	20167645	X	+	26627737	RPE1	viability after 18 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-2.026514227580241	[422]	[13,42]	-8	hSpCas9	negative selection	1421524
20266559	20266582	X	+	26627737	RPE1	viability after 18 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-2.156110217328503	[1180]	[27,117]	-8	hSpCas9	negative selection	1421525
20266593	20266616	X	-	26627737	RPE1	viability after 18 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	1.0170995766579836	[473]	[138,386]	6	hSpCas9	negative selection	1421526
20155433	20155456	X	+	26627737	HeLa	viability after 8 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.8466064394420636	[473]	[393,370,353]	7	hSpCas9	negative selection	1503836
20156163	20156186	X	-	26627737	HeLa	viability after 8 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-2.7547541815226966	[58]	[1,4,3]	-9	hSpCas9	negative selection	1503837
20161721	20161744	X	-	26627737	HeLa	viability after 8 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.10501121470445962	[587]	[445,228,193]	1	hSpCas9	negative selection	1503838
20167622	20167645	X	+	26627737	HeLa	viability after 8 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.4686995469274955	[353]	[125,52,154]	-4	hSpCas9	negative selection	1503839
20266559	20266582	X	+	26627737	HeLa	viability after 8 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.7052630656939163	[198]	[74,118,209]	6	hSpCas9	negative selection	1503840
20266593	20266616	X	-	26627737	HeLa	viability after 8 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-1.0626371769053229	[377]	[41,119,66]	-8	hSpCas9	negative selection	1503841
20155433	20155456	X	+	26627737	HeLa	viability after 12 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.661470822787604	[473]	[357,223,357]	5	hSpCas9	negative selection	1586151
20156163	20156186	X	-	26627737	HeLa	viability after 12 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-0.0913188597854746	[58]	[0,41,22]	-1	hSpCas9	negative selection	1586152
20161721	20161744	X	-	26627737	HeLa	viability after 12 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.03188471667832604	[587]	[272,247,191]	0	hSpCas9	negative selection	1586153
20167622	20167645	X	+	26627737	HeLa	viability after 12 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.684663958459926	[353]	[58,44,172]	-6	hSpCas9	negative selection	1586154
20266559	20266582	X	+	26627737	HeLa	viability after 12 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.3854735820760109	[198]	[23,124,168]	3	hSpCas9	negative selection	1586155
20266593	20266616	X	-	26627737	HeLa	viability after 12 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.8720907594912245	[377]	[56,77,120]	-7	hSpCas9	negative selection	1586156
20155433	20155456	X	+	26627737	HeLa	viability after 15 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.7120646915494553	[473]	[527,168,242]	5	hSpCas9	negative selection	1668466
20156163	20156186	X	-	26627737	HeLa	viability after 15 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-3.8291832310935643	[58]	[2,0,0]	-9	hSpCas9	negative selection	1668467
20161721	20161744	X	-	26627737	HeLa	viability after 15 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.021526793703684488	[587]	[286,181,237]	0	hSpCas9	negative selection	1668468
20167622	20167645	X	+	26627737	HeLa	viability after 15 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.027806030741532012	[353]	[34,145,252]	0	hSpCas9	negative selection	1668469
20266559	20266582	X	+	26627737	HeLa	viability after 15 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.007125660615822649	[198]	[0,50,199]	0	hSpCas9	negative selection	1668470
20266593	20266616	X	-	26627737	HeLa	viability after 15 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.6189036253643292	[377]	[105,124,66]	-5	hSpCas9	negative selection	1668471
20155433	20155456	X	+	26627737	HeLa	viability after 18 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.7148306527194392	[473]	[348,147,242]	5	hSpCas9	negative selection	1750781
20156163	20156186	X	-	26627737	HeLa	viability after 18 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-3.775475294890481	[58]	[1,0,0]	-9	hSpCas9	negative selection	1750782
20161721	20161744	X	-	26627737	HeLa	viability after 18 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.0069085102647770125	[587]	[196,150,237]	0	hSpCas9	negative selection	1750783
20167622	20167645	X	+	26627737	HeLa	viability after 18 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	0.02070234107310004	[353]	[27,126,252]	0	hSpCas9	negative selection	1750784
20266559	20266582	X	+	26627737	HeLa	viability after 18 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.028017720913415478	[198]	[0,38,199]	0	hSpCas9	negative selection	1750785
20266593	20266616	X	-	26627737	HeLa	viability after 18 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.6080281267617682	[377]	[76,97,66]	-5	hSpCas9	negative selection	1750786
20155433	20155456	X	+	26627737	HCT116	viability after 6 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.057155198331048096	[1078]	[202,140]	0	hSpCas9	negative selection	1833096
20156163	20156186	X	-	26627737	HCT116	viability after 6 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-3.11137753351935	[302]	[0,7]	-9	hSpCas9	negative selection	1833097
20161721	20161744	X	-	26627737	HCT116	viability after 6 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.3295883010569095	[971]	[318,121]	1	hSpCas9	negative selection	1833098
20167622	20167645	X	+	26627737	HCT116	viability after 6 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-2.8081447272161846	[484]	[26,1]	-9	hSpCas9	negative selection	1833099
20266559	20266582	X	+	26627737	HCT116	viability after 6 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-1.4930852394192815	[1309]	[38,91]	-7	hSpCas9	negative selection	1833100
20266593	20266616	X	-	26627737	HCT116	viability after 6 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.2522471683298184	[298]	[142,7]	1	hSpCas9	negative selection	1833101
20155433	20155456	X	+	26627737	HCT116	viability after 8 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.3464323324171688	[406]	[214,340,297]	4	hSpCas9	negative selection	1915411
20156163	20156186	X	-	26627737	HCT116	viability after 8 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.614516689584216	[11]	[57,39,23]	9	hSpCas9	negative selection	1915412
20161721	20161744	X	-	26627737	HCT116	viability after 8 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.13247470859493737	[465]	[414,248,183]	1	hSpCas9	negative selection	1915413
20167622	20167645	X	+	26627737	HCT116	viability after 8 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	0.15170258612624105	[330]	[136,211,256]	1	hSpCas9	negative selection	1915414
20266559	20266582	X	+	26627737	HCT116	viability after 8 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.718666229603129	[245]	[97,34,113]	-7	hSpCas9	negative selection	1915415
20266593	20266616	X	-	26627737	HCT116	viability after 8 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.47232376290750827	[227]	[96,207,215]	5	hSpCas9	negative selection	1915416
20155433	20155456	X	+	26627737	HCT116	viability after 9 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.009150818140975958	[1078]	[237,330]	0	hSpCas9	negative selection	1997726
20156163	20156186	X	-	26627737	HCT116	viability after 9 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-2.016906086272577	[302]	[0,34]	-8	hSpCas9	negative selection	1997727
20161721	20161744	X	-	26627737	HCT116	viability after 9 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.7508434773139091	[971]	[275,57]	-5	hSpCas9	negative selection	1997728
20167622	20167645	X	+	26627737	HCT116	viability after 9 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.5193768517325678	[484]	[148,43]	-4	hSpCas9	negative selection	1997729
20266559	20266582	X	+	26627737	HCT116	viability after 9 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-2.959953051196827	[1309]	[11,70]	-9	hSpCas9	negative selection	1997730
20266593	20266616	X	-	26627737	HCT116	viability after 9 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.7461070571879103	[298]	[191,87]	5	hSpCas9	negative selection	1997731
20155433	20155456	X	+	26627737	HCT116	viability after 12 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.3827273617871629	[406]	[260,353,224]	4	hSpCas9	negative selection	2080041
20156163	20156186	X	-	26627737	HCT116	viability after 12 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.662765495792337	[11]	[57,30,28]	9	hSpCas9	negative selection	2080042
20161721	20161744	X	-	26627737	HCT116	viability after 12 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.12109047442469689	[465]	[128,266,288]	-1	hSpCas9	negative selection	2080043
20167622	20167645	X	+	26627737	HCT116	viability after 12 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.1407733070731947	[330]	[142,172,158]	-1	hSpCas9	negative selection	2080044
20266559	20266582	X	+	26627737	HCT116	viability after 12 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.4109190415041413	[245]	[67,126,99]	-4	hSpCas9	negative selection	2080045
20266593	20266616	X	-	26627737	HCT116	viability after 12 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.40680983009767263	[227]	[95,196,189]	4	hSpCas9	negative selection	2080046
20155433	20155456	X	+	26627737	HCT116	viability after 15 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.6326948290577465	[406]	[410,392,289]	6	hSpCas9	negative selection	2162356
20156163	20156186	X	-	26627737	HCT116	viability after 15 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.5923280506764526	[11]	[37,23,61]	9	hSpCas9	negative selection	2162357
20161721	20161744	X	-	26627737	HCT116	viability after 15 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.23046691509468487	[465]	[177,252,246]	-2	hSpCas9	negative selection	2162358
20167622	20167645	X	+	26627737	HCT116	viability after 15 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.3070439066299048	[330]	[111,199,143]	-3	hSpCas9	negative selection	2162359
20266559	20266582	X	+	26627737	HCT116	viability after 15 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.09096116193587661	[245]	[115,154,124]	-1	hSpCas9	negative selection	2162360
20266593	20266616	X	-	26627737	HCT116	viability after 15 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.6632154800042782	[227]	[181,230,205]	6	hSpCas9	negative selection	2162361
20155433	20155456	X	+	26627737	HCT116	viability after 18 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	0.5024416883025253	[406]	[192,409,221]	4	hSpCas9	negative selection	2244671
20156163	20156186	X	-	26627737	HCT116	viability after 18 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	1.6316726919082076	[11]	[3,5,45]	9	hSpCas9	negative selection	2244672
20161721	20161744	X	-	26627737	HCT116	viability after 18 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.19048488616477122	[465]	[153,208,229]	-2	hSpCas9	negative selection	2244673
20167622	20167645	X	+	26627737	HCT116	viability after 18 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	0.36018536831437636	[330]	[199,217,196]	3	hSpCas9	negative selection	2244674
20266559	20266582	X	+	26627737	HCT116	viability after 18 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.6731427397498426	[245]	[55,62,106]	-6	hSpCas9	negative selection	2244675
20266593	20266616	X	-	26627737	HCT116	viability after 18 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.6620758722829911	[227]	[139,224,153]	5	hSpCas9	negative selection	2244676
20234768	20234791	X	+	24336569	HL60	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.3923127496357688	[226]	[365]	-3	hSpCas9	negative selection	2292978
20234775	20234798	X	-	24336569	HL60	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.5774477121445748	[937]	[2961]	5	hSpCas9	negative selection	2292979
20234783	20234806	X	-	24336569	HL60	viability	CAAATTATGGATGAACCTATGGG	RPS6KA3	ENSG00000177189	0.6784079964956446	[930]	[3152]	6	hSpCas9	negative selection	2292980
20234796	20234819	X	-	24336569	HL60	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.250068813637055	[1017]	[2561]	2	hSpCas9	negative selection	2292981
20266555	20266578	X	+	24336569	HL60	viability	TGCACTCACCTCAGCGCTGTCGG	RPS6KA3	ENSG00000177189	0.8229582393888725	[155]	[583]	6	hSpCas9	negative selection	2292982
20266560	20266583	X	+	24336569	HL60	viability	TCACCTCAGCGCTGTCGGACGGG	RPS6KA3	ENSG00000177189	0.6451790221694484	[532]	[1763]	5	hSpCas9	negative selection	2292983
20266586	20266609	X	+	24336569	HL60	viability	TCCACAGCCATCTTCTGCCACGG	RPS6KA3	ENSG00000177189	0.6121864518495569	[425]	[1377]	5	hSpCas9	negative selection	2292984
20266593	20266616	X	-	24336569	HL60	viability	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.09340842111553871	[848]	[1683]	-1	hSpCas9	negative selection	2292985
20266603	20266626	X	-	24336569	HL60	viability	TGGCGCAGCTGGCGGACCCGTGG	RPS6KA3	ENSG00000177189	-0.046042046418065086	[522]	[1071]	0	hSpCas9	negative selection	2292986
20266611	20266634	X	-	24336569	HL60	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.6307989460912798	[429]	[1408]	5	hSpCas9	negative selection	2292987
20234768	20234791	X	+	24336569	KBM7	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.7710494562446504	[116]	[186]	-5	hSpCas9	negative selection	2360155
20234775	20234798	X	-	24336569	KBM7	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.49753781992713075	[796]	[3068]	4	hSpCas9	negative selection	2360156
20234783	20234806	X	-	24336569	KBM7	viability	CAAATTATGGATGAACCTATGGG	RPS6KA3	ENSG00000177189	-0.2735497967738336	[1091]	[2463]	-2	hSpCas9	negative selection	2360157
20234796	20234819	X	-	24336569	KBM7	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.5411283467896522	[993]	[3944]	5	hSpCas9	negative selection	2360158
20266555	20266578	X	+	24336569	KBM7	viability	TGCACTCACCTCAGCGCTGTCGG	RPS6KA3	ENSG00000177189	1.6499373093653797	[142]	[1223]	9	hSpCas9	negative selection	2360159
20266560	20266583	X	+	24336569	KBM7	viability	TCACCTCAGCGCTGTCGGACGGG	RPS6KA3	ENSG00000177189	0.7891542478545865	[571]	[2695]	7	hSpCas9	negative selection	2360160
20266586	20266609	X	+	24336569	KBM7	viability	TCCACAGCCATCTTCTGCCACGG	RPS6KA3	ENSG00000177189	0.79292801934717	[276]	[1308]	7	hSpCas9	negative selection	2360161
20266593	20266616	X	-	24336569	KBM7	viability	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.5978637742122845	[374]	[1547]	5	hSpCas9	negative selection	2360162
20266603	20266626	X	-	24336569	KBM7	viability	TGGCGCAGCTGGCGGACCCGTGG	RPS6KA3	ENSG00000177189	0.7334131087962668	[403]	[1831]	6	hSpCas9	negative selection	2360163
20266611	20266634	X	-	24336569	KBM7	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.857802589458597	[455]	[2253]	7	hSpCas9	negative selection	2360164
20202028	20202051	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTACAGTGGTGCGATCCCGG	RPS6KA3	ENSG00000177189	0.022145587563181746	[17,17]	[3,2]	0	dCas9-VP64	positive selection	2432069
20266762	20266785	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGGCAGCAGCAGCAGCAGCGG	RPS6KA3	ENSG00000177189	0.013632045572814722	[22,8]	[3,1]	0	dCas9-VP64	positive selection	2436096
20266705	20266728	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCCCGAGCCCCACGGCAGCGG	RPS6KA3	ENSG00000177189	0.18316853420543722	[40,46]	[10,10]	0	dCas9-VP64	positive selection	2436098
20266791	20266814	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCGGCGTCGAGCCCTCTCTGGGG	RPS6KA3	ENSG00000177189	-1.2463051630216486	[815,67]	[66,10]	-7	dCas9-VP64	positive selection	2436099
20202028	20202051	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTACAGTGGTGCGATCCCGG	RPS6KA3	ENSG00000177189	-0.8807468495272488	[128,53]	[16,14]	-8	dCas9-VP64	positive selection	2527324
20266762	20266785	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGGCAGCAGCAGCAGCAGCGG	RPS6KA3	ENSG00000177189	0.7002266023200909	[12,5]	[4,3]	5	dCas9-VP64	positive selection	2531351
20266705	20266728	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCCCGAGCCCCACGGCAGCGG	RPS6KA3	ENSG00000177189	-0.32473349243796246	[35,362]	[38,61]	-3	dCas9-VP64	positive selection	2531353
20266791	20266814	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCGGCGTCGAGCCCTCTCTGGGG	RPS6KA3	ENSG00000177189	-0.05992377888506273	[188,167]	[31,77]	0	dCas9-VP64	positive selection	2531354
20187871	20187894	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.11892520615503582	[3,2]	[2,2]	2	hSpCas9	positive selection	3017978
20177047	20177070	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	0.09572357465369741	[3,3]	[4,1]	2	hSpCas9	positive selection	3017979
20234769	20234792	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.31148381768859357	[4,4]	[5,4]	6	hSpCas9	positive selection	3017980
20195129	20195152	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.09037929394964866	[3,3]	[2,3]	1	hSpCas9	positive selection	3017981
20187871	20187894	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.33422097648546484	[3,3]	[3,0]	-5	hSpCas9	positive selection	3085836
20177047	20177070	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	0.2863080621418082	[3,3]	[5,1]	5	hSpCas9	positive selection	3085837
20234769	20234792	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.15280448860465162	[4,4]	[5,2]	2	hSpCas9	positive selection	3085838
20195129	20195152	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.02505628051875608	[3,3]	[4,1]	0	hSpCas9	positive selection	3085839
20234796	20234819		-	24336571	A375	resistance to PLX after 7 days	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	-0.019311488388112807	[15,14]	[13,15]	0	hSpCas9	positive selection	3141893
20209359	20209382		-	24336571	A375	resistance to PLX after 7 days	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	-0.15216841968129607	[14,14]	[13,11]	-5	hSpCas9	positive selection	3141894
20234768	20234791		+	24336571	A375	resistance to PLX after 7 days	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.04117762158929106	[19,20]	[20,18]	-1	hSpCas9	positive selection	3141895
20209307	20209330		-	24336571	A375	resistance to PLX after 7 days	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	-0.5556854452118414	[5,5]	[2,3]	-9	hSpCas9	positive selection	3141896
20234796	20234819		-	24336571	A375	resistance to PLX after 14 days	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.015453827556038496	[17,9]	[5,6]	0	hSpCas9	positive selection	3199686
20209359	20209382		-	24336571	A375	resistance to PLX after 14 days	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	-0.9113169200555036	[21,16]	[4,3]	-9	hSpCas9	positive selection	3199687
20234768	20234791		+	24336571	A375	resistance to PLX after 14 days	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.3264655085814854	[24,23]	[8,8]	-4	hSpCas9	positive selection	3199688
20209307	20209330		-	24336571	A375	resistance to PLX after 14 days	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	0.1605442715342228	[5,4]	[1,2]	1	hSpCas9	positive selection	3199689
20234796	20234819		-	24336571	A375	viability after 7 days	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.5719569344490925	[10]	[15,14]	8	hSpCas9	negative selection	3257479
20209359	20209382		-	24336571	A375	viability after 7 days	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	-0.1591312829932948	[16]	[14,14]	-2	hSpCas9	negative selection	3257480
20234768	20234791		+	24336571	A375	viability after 7 days	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.12626177485530599	[23]	[19,20]	-2	hSpCas9	negative selection	3257481
20209307	20209330		-	24336571	A375	viability after 7 days	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	-0.007490586422746359	[5]	[5,5]	0	hSpCas9	negative selection	3257482
20234796	20234819		-	24336571	A375	viability after 14 days	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.45657681846534415	[10]	[17,9]	6	hSpCas9	negative selection	3315272
20209359	20209382		-	24336571	A375	viability after 14 days	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.21961381927771867	[16]	[21,16]	3	hSpCas9	negative selection	3315273
20234768	20234791		+	24336571	A375	viability after 14 days	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.13846419361111661	[23]	[24,23]	1	hSpCas9	negative selection	3315274
20209307	20209330		-	24336571	A375	viability after 14 days	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	-0.008273460923308829	[5]	[5,4]	0	hSpCas9	negative selection	3315275
20195104	20195127	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3390670
20234768	20234791	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-1.8459615969661867	[549,549]	[0,0]	-9	hSpCas9	positive selection	3390671
20195067	20195090	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3390672
20187871	20187894	X	-	26780180	HT29	viability (Avana library 4 designs)	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.716448766972018	[]	[]	2	hSpCas9	negative selection	3456359
20177046	20177069	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	1.28448853536966	[]	[]	5	hSpCas9	negative selection	3456360
20234768	20234791	X	+	26780180	HT29	viability (Avana library 4 designs)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.00898132126945808	[]	[]	0	hSpCas9	negative selection	3456361
20195129	20195152	X	-	26780180	HT29	viability (Avana library 4 designs)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.0335765249150324	[]	[]	0	hSpCas9	negative selection	3456362
20234768	20234791	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.243911529006146	[]	[]	0	hSpCas9	negative selection	3554798
20187871	20187894	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	1.72670373260754	[]	[]	2	hSpCas9	negative selection	3554799
20177046	20177069	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	-1.45727751448805	[]	[]	-2	hSpCas9	negative selection	3554800
20195129	20195152	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	3.66657393340886	[]	[]	6	hSpCas9	negative selection	3554801
20194188	20194211	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTACACGCTTATCCAAAGAGG	RPS6KA3	ENSG00000177189	-0.292613627165776	[]	[]	0	hSpCas9	negative selection	3554802
20176306	20176329	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCGTTGCAGGTTTAAATGGCGG	RPS6KA3	ENSG00000177189	3.81468616807322	[]	[]	6	hSpCas9	negative selection	3554803
20234768	20234791	X	+	26780180	A375	viability (Avana lentiGuide)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.412564254916498	[]	[]	0	hSpCas9	negative selection	3663457
20187871	20187894	X	-	26780180	A375	viability (Avana lentiGuide)	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	3.76625427303873	[]	[]	3	hSpCas9	negative selection	3663458
20177046	20177069	X	+	26780180	A375	viability (Avana lentiGuide)	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	-1.84087691010928	[]	[]	-3	hSpCas9	negative selection	3663459
20195129	20195152	X	-	26780180	A375	viability (Avana lentiGuide)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.532734337040615	[]	[]	-1	hSpCas9	negative selection	3663460
20194188	20194211	X	-	26780180	A375	viability (Avana lentiGuide)	GTTTACACGCTTATCCAAAGAGG	RPS6KA3	ENSG00000177189	0.301997018999214	[]	[]	0	hSpCas9	negative selection	3663461
20176306	20176329	X	+	26780180	A375	viability (Avana lentiGuide)	CCCGTTGCAGGTTTAAATGGCGG	RPS6KA3	ENSG00000177189	-4.32333800107074	[]	[]	-7	hSpCas9	negative selection	3663462
20234768	20234791	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.22463425756677283	[6]	[5,4]	-4	hSpCas9	positive selection	3772064
20187871	20187894	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.36802218256078784	[5]	[4,2]	-5	hSpCas9	positive selection	3772065
20177046	20177069	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	-0.3451137720516957	[5]	[3,3]	-5	hSpCas9	positive selection	3772066
20195129	20195152	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.21310816202043115	[5]	[6,6]	6	hSpCas9	positive selection	3772067
20194188	20194211	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTACACGCTTATCCAAAGAGG	RPS6KA3	ENSG00000177189	-0.20250531934887217	[6]	[5,4]	-3	hSpCas9	positive selection	3772068
20176306	20176329	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCGTTGCAGGTTTAAATGGCGG	RPS6KA3	ENSG00000177189	0.24648923758516122	[4]	[5,5]	7	hSpCas9	positive selection	3772069
20234768	20234791	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.016588919920240974	[6]	[5,6]	0	hSpCas9	positive selection	3880671
20187871	20187894	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.3664805615295253	[5]	[4,2]	-5	hSpCas9	positive selection	3880672
20177046	20177069	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAGGACTCAAAAACTGTGG	RPS6KA3	ENSG00000177189	0.3399230282412864	[5]	[5,5]	8	hSpCas9	positive selection	3880673
20195129	20195152	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.2698293366240569	[5]	[6,6]	7	hSpCas9	positive selection	3880674
20194188	20194211	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTACACGCTTATCCAAAGAGG	RPS6KA3	ENSG00000177189	0.1426946407740529	[6]	[6,5]	3	hSpCas9	positive selection	3880675
20176306	20176329	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCGTTGCAGGTTTAAATGGCGG	RPS6KA3	ENSG00000177189	0.15520209058015133	[5]	[5,4]	3	hSpCas9	positive selection	3880676
20195104	20195127	X	-	26780180	A375	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.84309298645628	[]	[]	3	hSpCas9	negative selection	3990695
20234796	20234819	X	-	26780180	A375	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.391998948897992	[]	[]	0	hSpCas9	negative selection	3990696
20195067	20195090	X	+	26780180	A375	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.965815106833494	[]	[]	4	hSpCas9	negative selection	3990697
20209359	20209382	X	-	26780180	A375	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.95207466377104	[]	[]	4	hSpCas9	negative selection	3990698
20234768	20234791	X	+	26780180	A375	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.102496566607208	[]	[]	-3	hSpCas9	negative selection	3990699
20195129	20195152	X	-	26780180	A375	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.941240898035438	[]	[]	4	hSpCas9	negative selection	3990700
20195104	20195127	X	-	26780180	HT29	viability (GeCKOv2 library)	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.907173214301245	[]	[]	4	hSpCas9	negative selection	4098661
20234796	20234819	X	-	26780180	HT29	viability (GeCKOv2 library)	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	-0.164166468584651	[]	[]	-5	hSpCas9	negative selection	4098662
20195067	20195090	X	+	26780180	HT29	viability (GeCKOv2 library)	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.642465049758648	[]	[]	2	hSpCas9	negative selection	4098663
20209359	20209382	X	-	26780180	HT29	viability (GeCKOv2 library)	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	1.15217776650896	[]	[]	5	hSpCas9	negative selection	4098664
20234768	20234791	X	+	26780180	HT29	viability (GeCKOv2 library)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.299815063763334	[]	[]	-7	hSpCas9	negative selection	4098665
20195129	20195152	X	-	26780180	HT29	viability (GeCKOv2 library)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.84504107799987	[]	[]	3	hSpCas9	negative selection	4098666
20234796	20234819	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.10311579807728313	[3]	[2,2]	2	hSpCas9	positive selection	4167580
20209359	20209382	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	-0.051203847883408836	[3]	[2,1]	-1	hSpCas9	positive selection	4167581
20234768	20234791	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.38370270511055504	[4]	[4,3]	8	hSpCas9	positive selection	4167582
20209307	20209330	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	0.30250614964943784	[1]	[2,1]	7	hSpCas9	positive selection	4167583
20234796	20234819	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.04197916809096097	[2]	[0,3,0,0]	0	hSpCas9	positive selection	4231602
20209359	20209382	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.7238320463080847	[3]	[3,4,6,0]	5	hSpCas9	positive selection	4231603
20234768	20234791	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	1.087808730660061	[4]	[4,3,2,4]	7	hSpCas9	positive selection	4231604
20209307	20209330	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTGAACTTTTAAAAGTATTAGG	RPS6KA3	ENSG00000177189	1.884717679674536	[0]	[2,0,1,0]	9	hSpCas9	positive selection	4231605
20195129	20195152	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.533107071627124	[3]	[4,4]	9	hSpCas9	positive selection	4295795
20209359	20209382	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.09880844936529154	[3]	[3,2]	2	hSpCas9	positive selection	4295796
20234796	20234819	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	-0.11660286199635372	[2]	[2,0]	-2	hSpCas9	positive selection	4295797
20195104	20195127	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.05626798971388293	[2]	[2,1]	1	hSpCas9	positive selection	4360048
20234768	20234791	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.47446553924072354	[4]	[4,5]	8	hSpCas9	positive selection	4360049
20195067	20195090	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.2713143417950913	[2]	[2,2]	5	hSpCas9	positive selection	4360050
20176483	20176505	X	-	27760321	OCIAML3	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.6076685132222268	[403,331]	[353,543]	7	hSpCas9	negative selection	4435953
20187871	20187893	X	-	27760321	OCIAML3	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.3608085148526392	[431,356]	[213,271]	-4	hSpCas9	negative selection	4435954
20195098	20195120	X	-	27760321	OCIAML3	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.17223561525853426	[212,176]	[128,225]	2	hSpCas9	negative selection	4435955
20175279	20175301	X	-	27760321	OCIAML3	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	0.792240045512592	[255,241]	[258,439]	8	hSpCas9	negative selection	4435956
20176307	20176329	X	-	27760321	OCIAML3	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	-0.4277221818694138	[464,301]	[188,259]	-4	hSpCas9	negative selection	4435957
20176483	20176505	X	-	27760321	OCIAML2	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.01980965151381922	[403,331]	[223,400]	0	hSpCas9	negative selection	4519416
20187871	20187893	X	-	27760321	OCIAML2	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.08541407301197418	[431,356]	[305,377]	1	hSpCas9	negative selection	4519417
20195098	20195120	X	-	27760321	OCIAML2	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.39018548599478353	[212,176]	[185,231]	5	hSpCas9	negative selection	4519418
20175279	20175301	X	-	27760321	OCIAML2	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.13756732700593144	[255,241]	[140,238]	-2	hSpCas9	negative selection	4519419
20176307	20176329	X	-	27760321	OCIAML2	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.5134117032634093	[464,301]	[436,435]	7	hSpCas9	negative selection	4519420
20176483	20176505	X	-	27760321	MV411	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	-1.387773728746529	[403,331]	[47,158]	-7	hSpCas9	negative selection	4602879
20187871	20187893	X	-	27760321	MV411	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.1562474144458136	[431,356]	[176,315]	-1	hSpCas9	negative selection	4602880
20195098	20195120	X	-	27760321	MV411	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-1.5752354669578081	[212,176]	[40,45]	-7	hSpCas9	negative selection	4602881
20175279	20175301	X	-	27760321	MV411	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.2648871909255446	[255,241]	[0,340]	-2	hSpCas9	negative selection	4602882
20176307	20176329	X	-	27760321	MV411	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	1.2662772912380051	[464,301]	[743,383]	8	hSpCas9	negative selection	4602883
20176483	20176505	X	-	27760321	HL60	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.009812315183211628	[403,331]	[258,345]	0	hSpCas9	negative selection	4686342
20187871	20187893	X	-	27760321	HL60	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.6394779651150901	[431,356]	[236,172]	-6	hSpCas9	negative selection	4686343
20195098	20195120	X	-	27760321	HL60	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	1.0758707753878636	[212,176]	[295,374]	9	hSpCas9	negative selection	4686344
20175279	20175301	X	-	27760321	HL60	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	0.26747994608694825	[255,241]	[230,259]	3	hSpCas9	negative selection	4686345
20176307	20176329	X	-	27760321	HL60	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.62152978465199	[464,301]	[479,469]	7	hSpCas9	negative selection	4686346
20176483	20176505	X	-	27760321	HT1080	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	-1.6588765955218825	[331,258]	[0,76]	-5	hSpCas9	negative selection	4769805
20187871	20187893	X	-	27760321	HT1080	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-3.159279700834579	[356,278]	[17,9]	-7	hSpCas9	negative selection	4769806
20195098	20195120	X	-	27760321	HT1080	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-1.7492657815152783	[176,137]	[0,37]	-6	hSpCas9	negative selection	4769807
20175279	20175301	X	-	27760321	HT1080	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.5550992770598707	[241,188]	[56,59]	-2	hSpCas9	negative selection	4769808
20176307	20176329	X	-	27760321	HT1080	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	-2.1355266210546877	[301,235]	[0,49]	-6	hSpCas9	negative selection	4769809
20176483	20176505	X	-	27760321	HT29	viability after 7 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.06817580271111973	[331,258]	[375,284,525]	1	hSpCas9	negative selection	4853268
20187871	20187893	X	-	27760321	HT29	viability after 7 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.39517696805276215	[356,278]	[391,276,275]	-5	hSpCas9	negative selection	4853269
20195098	20195120	X	-	27760321	HT29	viability after 7 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.6258630448896667	[176,137]	[127,228,38]	-7	hSpCas9	negative selection	4853270
20175279	20175301	X	-	27760321	HT29	viability after 7 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.5578477022848821	[241,188]	[233,277,62]	-7	hSpCas9	negative selection	4853271
20176307	20176329	X	-	27760321	HT29	viability after 7 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.252747859593238	[301,235]	[578,473,212]	4	hSpCas9	negative selection	4853272
20176483	20176505	X	-	27760321	HT29	viability after 25 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.4015161707381708	[331,258]	[342,597,397]	4	hSpCas9	negative selection	4936731
20187871	20187893	X	-	27760321	HT29	viability after 25 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.35441911078084515	[356,278]	[476,411,507]	4	hSpCas9	negative selection	4936732
20195098	20195120	X	-	27760321	HT29	viability after 25 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.23003929990408722	[176,137]	[52,263,148]	-2	hSpCas9	negative selection	4936733
20175279	20175301	X	-	27760321	HT29	viability after 25 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.5614528687152335	[241,188]	[206,191,90]	-5	hSpCas9	negative selection	4936734
20176307	20176329	X	-	27760321	HT29	viability after 25 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.3086849082289027	[301,235]	[416,328,394]	3	hSpCas9	negative selection	4936735
20176483	20176505	X	-	27760321	HT29	viability after 22 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.708034401486064	[331,258]	[679,514,474]	7	hSpCas9	negative selection	5020194
20187871	20187893	X	-	27760321	HT29	viability after 22 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.14191282375848785	[356,278]	[430,407,376]	1	hSpCas9	negative selection	5020195
20195098	20195120	X	-	27760321	HT29	viability after 22 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.2205633053495908	[176,137]	[190,336,107]	2	hSpCas9	negative selection	5020196
20175279	20175301	X	-	27760321	HT29	viability after 22 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.36070912444108527	[241,188]	[209,243,126]	-4	hSpCas9	negative selection	5020197
20176307	20176329	X	-	27760321	HT29	viability after 22 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.5557372596473938	[301,235]	[644,404,314]	6	hSpCas9	negative selection	5020198
20176483	20176505	X	-	27760321	HT29	viability after 19 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	-0.04885729616208245	[331,258]	[474,236,284]	0	hSpCas9	negative selection	5103657
20187871	20187893	X	-	27760321	HT29	viability after 19 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.5931057193593134	[356,278]	[319,104,303]	-5	hSpCas9	negative selection	5103658
20195098	20195120	X	-	27760321	HT29	viability after 19 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.06591273768358574	[176,137]	[225,277,69]	0	hSpCas9	negative selection	5103659
20175279	20175301	X	-	27760321	HT29	viability after 19 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.7200043696729809	[241,188]	[233,83,139]	-5	hSpCas9	negative selection	5103660
20176307	20176329	X	-	27760321	HT29	viability after 19 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.7312840628127822	[301,235]	[587,412,537]	7	hSpCas9	negative selection	5103661
20176483	20176505	X	-	27760321	HT29	viability after 16 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.40974995945998016	[331,258]	[503,538,277]	4	hSpCas9	negative selection	5187120
20187871	20187893	X	-	27760321	HT29	viability after 16 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	0.45032951473850413	[356,278]	[309,591,536]	5	hSpCas9	negative selection	5187121
20195098	20195120	X	-	27760321	HT29	viability after 16 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.6308234719513858	[176,137]	[257,351,204]	7	hSpCas9	negative selection	5187122
20175279	20175301	X	-	27760321	HT29	viability after 16 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	0.11665530198315477	[241,188]	[425,213,160]	1	hSpCas9	negative selection	5187123
20176307	20176329	X	-	27760321	HT29	viability after 16 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.9165710157574138	[301,235]	[680,452,583]	9	hSpCas9	negative selection	5187124
20176483	20176505	X	-	27760321	HT29	viability after 13 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.49344166800880285	[331,258]	[304,419,708]	6	hSpCas9	negative selection	5270583
20187871	20187893	X	-	27760321	HT29	viability after 13 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.14351384842974588	[356,278]	[294,337,366]	-2	hSpCas9	negative selection	5270584
20195098	20195120	X	-	27760321	HT29	viability after 13 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.2940203865597316	[176,137]	[185,277,208]	3	hSpCas9	negative selection	5270585
20175279	20175301	X	-	27760321	HT29	viability after 13 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	-0.49672961441842445	[241,188]	[218,161,151]	-5	hSpCas9	negative selection	5270586
20176307	20176329	X	-	27760321	HT29	viability after 13 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.7415275638913292	[301,235]	[355,675,532]	8	hSpCas9	negative selection	5270587
20176483	20176505	X	-	27760321	HT29	viability after 10 days	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.520073031903565	[331,258]	[619,445,518]	7	hSpCas9	negative selection	5354046
20187871	20187893	X	-	27760321	HT29	viability after 10 days	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.9211624896037561	[356,278]	[158,331,142]	-7	hSpCas9	negative selection	5354047
20195098	20195120	X	-	27760321	HT29	viability after 10 days	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.48842154998855347	[176,137]	[157,397,274]	6	hSpCas9	negative selection	5354048
20175279	20175301	X	-	27760321	HT29	viability after 10 days	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	0.022229683930773403	[241,188]	[342,347,133]	0	hSpCas9	negative selection	5354049
20176307	20176329	X	-	27760321	HT29	viability after 10 days	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	0.6518518726428889	[301,235]	[490,340,740]	8	hSpCas9	negative selection	5354050
20176483	20176505	X	-	27760321	MOLM13	viability	TGATAGGTGCAGGACCAGATGG	RPS6KA3	ENSG00000177189	0.35132276685088637	[403,331]	[214,304]	2	hSpCas9	negative selection	5437509
20187871	20187893	X	-	27760321	MOLM13	viability	CAGAAGTAGTTAATCGTCGAGG	RPS6KA3	ENSG00000177189	-0.37426772481727366	[431,356]	[238,112]	-2	hSpCas9	negative selection	5437510
20195098	20195120	X	-	27760321	MOLM13	viability	GAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.030258995927889387	[212,176]	[153,75]	0	hSpCas9	negative selection	5437511
20175279	20175301	X	-	27760321	MOLM13	viability	TACTCTTTTCAGATTCACCTGG	RPS6KA3	ENSG00000177189	0.871290888877601	[255,241]	[327,196]	6	hSpCas9	negative selection	5437512
20176307	20176329	X	-	27760321	MOLM13	viability	CCGCCATTTAAACCTGCAACGG	RPS6KA3	ENSG00000177189	2.2157737122650136	[464,301]	[1106,891]	9	hSpCas9	negative selection	5437513
20266443	20266466	X	+	27661255	K562	viability	GCCCGGGGGAAAGACGCGAGCGG	RPS6KA3	ENSG00000177189	0.09827927277786452	[226,237]	[216,182]	3	dCas9-KRAB	negative selection	5508628
20266455	20266478	X	+	27661255	K562	viability	GACGCGAGCGGGATCAGAACGGG	RPS6KA3	ENSG00000177189	-0.0009218028927656385	[876,917]	[791,650]	0	dCas9-KRAB	negative selection	5508629
20266866	20266889	X	+	27661255	K562	viability	GAGAGCCTCGCGCCTCCGCTGGG	RPS6KA3	ENSG00000177189	0.0985826372549995	[1081,1353]	[1036,1037]	3	dCas9-KRAB	negative selection	5508630
20266593	20266616	X	-	27661255	K562	viability	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.2986913461975167	[606,686]	[670,602]	8	dCas9-KRAB	negative selection	5508631
20266838	20266861	X	-	27661255	K562	viability	GCGCGCGGGCGTCTCTGGCCAGG	RPS6KA3	ENSG00000177189	0.032546934659636984	[237,216]	[176,193]	1	dCas9-KRAB	negative selection	5508632
20195129	20195152	X	-	27260156	BXPC3	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.0741550694280555	[731]	[629,814,483,1009]	-2	hSpCas9	negative selection	5568255
20209359	20209382	X	-	27260156	BXPC3	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.21250512322493476	[521]	[597,611,672,649]	5	hSpCas9	negative selection	5568256
20234796	20234819	X	-	27260156	BXPC3	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.2695640945195395	[276]	[290,343,342,432]	6	hSpCas9	negative selection	5568257
20195104	20195127	X	-	27260156	BXPC3	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.304149559612672	[378]	[269,313,289,425]	-6	hSpCas9	negative selection	5632508
20234768	20234791	X	+	27260156	BXPC3	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.1128710698803006	[1435]	[1428,1494,1592,2046]	2	hSpCas9	negative selection	5632509
20195067	20195090	X	+	27260156	BXPC3	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.022935427164585048	[405]	[402,367,427,481]	0	hSpCas9	negative selection	5632510
20195129	20195152	X	-	27260156	A673	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.28023270556604035	[731]	[707,670,695,823]	-6	hSpCas9	negative selection	5689506
20209359	20209382	X	-	27260156	A673	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.21335049083087282	[521]	[735,723,740,703]	5	hSpCas9	negative selection	5689507
20234796	20234819	X	-	27260156	A673	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.27792635536017013	[276]	[429,455,334,392]	6	hSpCas9	negative selection	5689508
20195104	20195127	X	-	27260156	A673	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.1528551789506732	[378]	[373,369,461,427]	-4	hSpCas9	negative selection	5753759
20234768	20234791	X	+	27260156	A673	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.25302719325102885	[1435]	[2373,1855,1999,2025]	6	hSpCas9	negative selection	5753760
20195067	20195090	X	+	27260156	A673	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.1705958867932567	[405]	[590,489,582,534]	4	hSpCas9	negative selection	5753761
20195129	20195152	X	-	27260156	A375	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.0340677179060731	[731]	[938,1282,759,605]	0	hSpCas9	negative selection	5810757
20209359	20209382	X	-	27260156	A375	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.7477855985744224	[521]	[1155,1066,1089,810]	9	hSpCas9	negative selection	5810758
20234796	20234819	X	-	27260156	A375	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.4514518779279389	[276]	[548,624,324,310]	6	hSpCas9	negative selection	5810759
20195104	20195127	X	-	27260156	A375	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.4150447713813593	[378]	[331,392,294,316]	-5	hSpCas9	negative selection	5875010
20234768	20234791	X	+	27260156	A375	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.41815514693546185	[1435]	[2015,2762,2396,1892]	6	hSpCas9	negative selection	5875011
20195067	20195090	X	+	27260156	A375	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.3599774431341436	[405]	[506,677,564,681]	5	hSpCas9	negative selection	5875012
20195129	20195152	X	-	27260156	COLO741	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.09653191976946052	[731]	[1179,682,790]	-2	hSpCas9	negative selection	5932008
20209359	20209382	X	-	27260156	COLO741	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.28726356502495987	[521]	[1002,853,613]	6	hSpCas9	negative selection	5932009
20234796	20234819	X	-	27260156	COLO741	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	-0.28792338974147813	[276]	[348,277,249]	-6	hSpCas9	negative selection	5932010
20195104	20195127	X	-	27260156	COLO741	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.15874917968188773	[378]	[465,471,369]	-3	hSpCas9	negative selection	5996261
20234768	20234791	X	+	27260156	COLO741	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.20708511600608803	[1435]	[2520,2125,1762]	4	hSpCas9	negative selection	5996262
20195067	20195090	X	+	27260156	COLO741	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.019670023825944377	[405]	[605,533,448]	0	hSpCas9	negative selection	5996263
20195129	20195152	X	-	27260156	CAL120	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.021285477939599784	[731]	[769,1408,576]	0	hSpCas9	negative selection	6053259
20209359	20209382	X	-	27260156	CAL120	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.5750235704889191	[521]	[739,917,1205]	8	hSpCas9	negative selection	6053260
20234796	20234819	X	-	27260156	CAL120	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.2867551006555266	[276]	[521,357,396]	4	hSpCas9	negative selection	6053261
20195104	20195127	X	-	27260156	CAL120	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.1888589549890793	[378]	[786,489,375]	3	hSpCas9	negative selection	6117512
20234768	20234791	X	+	27260156	CAL120	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.16651542212177128	[1435]	[2447,1828,1808]	2	hSpCas9	negative selection	6117513
20195067	20195090	X	+	27260156	CAL120	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.32383369235883536	[405]	[897,585,455]	5	hSpCas9	negative selection	6117514
20195129	20195152	X	-	27260156	CADOES1	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.14519717387496162	[731]	[537,780,452,693]	-3	hSpCas9	negative selection	6174510
20209359	20209382	X	-	27260156	CADOES1	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.41903932841453073	[521]	[763,665,446,721]	7	hSpCas9	negative selection	6174511
20234796	20234819	X	-	27260156	CADOES1	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.4936899133461539	[276]	[426,433,201,388]	7	hSpCas9	negative selection	6174512
20195104	20195127	X	-	27260156	CADOES1	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.19921303217774033	[378]	[334,293,368,226]	-3	hSpCas9	negative selection	6238763
20234768	20234791	X	+	27260156	CADOES1	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.03214552147896854	[1435]	[1219,1160,1521,1321]	0	hSpCas9	negative selection	6238764
20195067	20195090	X	+	27260156	CADOES1	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.2637755979553403	[405]	[438,552,334,487]	4	hSpCas9	negative selection	6238765
20195129	20195152	X	-	27260156	EWS502	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.12426552275346447	[731]	[699,711,624,812]	-2	hSpCas9	negative selection	6295761
20209359	20209382	X	-	27260156	EWS502	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.6001781039563402	[521]	[828,675,862,1000]	9	hSpCas9	negative selection	6295762
20234796	20234819	X	-	27260156	EWS502	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.04673811758660118	[276]	[269,296,343,304]	0	hSpCas9	negative selection	6295763
20195104	20195127	X	-	27260156	EWS502	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.0714501979344494	[378]	[447,391,415,427]	1	hSpCas9	negative selection	6360014
20234768	20234791	X	+	27260156	EWS502	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.05366022399455361	[1435]	[1611,1533,1390,1780]	0	hSpCas9	negative selection	6360015
20195067	20195090	X	+	27260156	EWS502	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.2769502188465253	[405]	[462,428,587,620]	5	hSpCas9	negative selection	6360016
20195129	20195152	X	-	27260156	EW8	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.1247270437398168	[731]	[655,458,579,900]	2	hSpCas9	negative selection	6417012
20209359	20209382	X	-	27260156	EW8	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.35891311815500604	[521]	[695,571,476,451]	6	hSpCas9	negative selection	6417013
20234796	20234819	X	-	27260156	EW8	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.18337713239158615	[276]	[253,282,170,324]	3	hSpCas9	negative selection	6417014
20195104	20195127	X	-	27260156	EW8	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.17898372082832475	[378]	[483,365,319,239]	3	hSpCas9	negative selection	6481265
20234768	20234791	X	+	27260156	EW8	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.35618569204345074	[1435]	[1796,1438,1180,1622]	6	hSpCas9	negative selection	6481266
20195067	20195090	X	+	27260156	EW8	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.0584487519819851	[405]	[155,569,206,331]	-1	hSpCas9	negative selection	6481267
20195129	20195152	X	-	27260156	CORL105	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.06738451265547263	[731]	[1025,762,1026,802]	1	hSpCas9	negative selection	6538263
20209359	20209382	X	-	27260156	CORL105	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.389368296740613	[521]	[723,699,968,833]	7	hSpCas9	negative selection	6538264
20234796	20234819	X	-	27260156	CORL105	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.4850112392578876	[276]	[427,444,444,494]	8	hSpCas9	negative selection	6538265
20195104	20195127	X	-	27260156	CORL105	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.002469631455558452	[378]	[527,354,542,371]	0	hSpCas9	negative selection	6602516
20234768	20234791	X	+	27260156	CORL105	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.04810501231393571	[1435]	[1716,1635,1740,1858]	0	hSpCas9	negative selection	6602517
20195067	20195090	X	+	27260156	CORL105	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.29177876018328036	[405]	[559,508,572,683]	5	hSpCas9	negative selection	6602518
20195129	20195152	X	-	27260156	HS294T	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.17566993984414636	[731]	[434,167,386,273]	2	hSpCas9	negative selection	6659514
20209359	20209382	X	-	27260156	HS294T	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.5747058730756744	[521]	[343,316,242,290]	7	hSpCas9	negative selection	6659515
20234796	20234819	X	-	27260156	HS294T	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.2685708434905629	[276]	[165,90,98,162]	3	hSpCas9	negative selection	6659516
20195104	20195127	X	-	27260156	HS294T	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.7051972725426426	[378]	[51,63,121,132]	-7	hSpCas9	negative selection	6723767
20234768	20234791	X	+	27260156	HS294T	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.23857620339978625	[1435]	[448,431,483,528]	-3	hSpCas9	negative selection	6723768
20195067	20195090	X	+	27260156	HS294T	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.17301536784438923	[405]	[153,154,130,288]	2	hSpCas9	negative selection	6723769
20195129	20195152	X	-	27260156	HCC44	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.18105508829843697	[731]	[742,680,1417,1003]	3	hSpCas9	negative selection	6780765
20209359	20209382	X	-	27260156	HCC44	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.4778106248872346	[521]	[1432,600,955,415]	7	hSpCas9	negative selection	6780766
20234796	20234819	X	-	27260156	HCC44	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.3023735481331901	[276]	[319,423,349,428]	5	hSpCas9	negative selection	6780767
20195104	20195127	X	-	27260156	HCC44	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.3247011407427992	[378]	[368,328,457,237]	-5	hSpCas9	negative selection	6845018
20234768	20234791	X	+	27260156	HCC44	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.1834039292890517	[1435]	[1695,2096,2176,1413]	3	hSpCas9	negative selection	6845019
20195067	20195090	X	+	27260156	HCC44	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.14575559327795234	[405]	[694,366,555,456]	2	hSpCas9	negative selection	6845020
20195129	20195152	X	-	27260156	G402	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.3185502712389937	[731]	[1165,1665,591,1068]	4	hSpCas9	negative selection	6902016
20209359	20209382	X	-	27260156	G402	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.9440402286878937	[521]	[1874,890,1354,867]	9	hSpCas9	negative selection	6902017
20234796	20234819	X	-	27260156	G402	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.920985839832956	[276]	[659,436,398,1032]	9	hSpCas9	negative selection	6902018
20195104	20195127	X	-	27260156	G402	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.05134521706809708	[378]	[619,444,466,404]	0	hSpCas9	negative selection	6966269
20234768	20234791	X	+	27260156	G402	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.1309457737060684	[1435]	[1860,1662,1421,1494]	-2	hSpCas9	negative selection	6966270
20195067	20195090	X	+	27260156	G402	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.049167252533917044	[405]	[641,556,486,265]	0	hSpCas9	negative selection	6966271
20195129	20195152	X	-	27260156	L33	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.3260244528689403	[731]	[514,276,332,615]	-6	hSpCas9	negative selection	7023267
20209359	20209382	X	-	27260156	L33	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.4549429530895601	[521]	[629,259,486,823]	8	hSpCas9	negative selection	7023268
20234796	20234819	X	-	27260156	L33	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.435997964295798	[276]	[359,120,222,487]	8	hSpCas9	negative selection	7023269
20195104	20195127	X	-	27260156	L33	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.498930208677821	[378]	[258,92,192,279]	-8	hSpCas9	negative selection	7087520
20234768	20234791	X	+	27260156	L33	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.13999822928726235	[1435]	[1592,788,1039,1159]	3	hSpCas9	negative selection	7087521
20195067	20195090	X	+	27260156	L33	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.16050974104266996	[405]	[436,180,277,493]	3	hSpCas9	negative selection	7087522
20195129	20195152	X	-	27260156	K562	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.46764989107119354	[731]	[559,632,390,325]	-5	hSpCas9	negative selection	7144518
20209359	20209382	X	-	27260156	K562	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.8674836250412754	[521]	[692,1515,469,733]	9	hSpCas9	negative selection	7144519
20234796	20234819	X	-	27260156	K562	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.12743638506766963	[276]	[270,191,411,201]	1	hSpCas9	negative selection	7144520
20195104	20195127	X	-	27260156	K562	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.5463747842148616	[378]	[328,1100,263,308]	7	hSpCas9	negative selection	7208771
20234768	20234791	X	+	27260156	K562	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.38091386049417175	[1435]	[1757,2080,1126,1690]	5	hSpCas9	negative selection	7208772
20195067	20195090	X	+	27260156	K562	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.19216896330237423	[405]	[230,488,223,317]	-2	hSpCas9	negative selection	7208773
20195129	20195152	X	-	27260156	HT29	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.035630870114643054	[731]	[1007,948,924,785]	0	hSpCas9	negative selection	7265769
20209359	20209382	X	-	27260156	HT29	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.49207591202023515	[521]	[1240,960,626,780]	8	hSpCas9	negative selection	7265770
20234796	20234819	X	-	27260156	HT29	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.07141284671794168	[276]	[335,335,403,335]	1	hSpCas9	negative selection	7265771
20195104	20195127	X	-	27260156	HT29	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.021341556933628048	[378]	[402,531,396,479]	0	hSpCas9	negative selection	7330022
20234768	20234791	X	+	27260156	HT29	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.2060456890537572	[1435]	[2389,1880,1877,1919]	4	hSpCas9	negative selection	7330023
20195067	20195090	X	+	27260156	HT29	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.06384013791426163	[405]	[535,539,638,366]	1	hSpCas9	negative selection	7330024
20195129	20195152	X	-	27260156	MHHES1	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.25660381501264073	[731]	[1069,490,629,599]	-5	hSpCas9	negative selection	7387020
20209359	20209382	X	-	27260156	MHHES1	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.47268820263027567	[521]	[965,885,705,730]	8	hSpCas9	negative selection	7387021
20234796	20234819	X	-	27260156	MHHES1	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.7604814090276739	[276]	[488,761,575,338]	9	hSpCas9	negative selection	7387022
20195104	20195127	X	-	27260156	MHHES1	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.1373502280405739	[378]	[326,379,432,655]	2	hSpCas9	negative selection	7451273
20234768	20234791	X	+	27260156	MHHES1	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.23022260435770447	[1435]	[1967,2084,1953,1628]	4	hSpCas9	negative selection	7451274
20195067	20195090	X	+	27260156	MHHES1	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.0049030898363007225	[405]	[676,406,500,288]	0	hSpCas9	negative selection	7451275
20195129	20195152	X	-	27260156	MEWO	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.015087539777918213	[731]	[804,601,650]	0	hSpCas9	negative selection	7508271
20209359	20209382	X	-	27260156	MEWO	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.1655465073031573	[521]	[661,597,404]	3	hSpCas9	negative selection	7508272
20234796	20234819	X	-	27260156	MEWO	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.32524722089488345	[276]	[385,295,303]	7	hSpCas9	negative selection	7508273
20195104	20195127	X	-	27260156	MEWO	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.11450496568704291	[378]	[376,421,350]	2	hSpCas9	negative selection	7572524
20234768	20234791	X	+	27260156	MEWO	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.41176397877718185	[1435]	[2267,1465,1721]	8	hSpCas9	negative selection	7572525
20195067	20195090	X	+	27260156	MEWO	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.021227540839212494	[405]	[318,475,347]	0	hSpCas9	negative selection	7572526
20195129	20195152	X	-	27260156	LNCAPCLONEFGC	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.18865199129919297	[731]	[944,754,669,635]	3	hSpCas9	negative selection	7629522
20209359	20209382	X	-	27260156	LNCAPCLONEFGC	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.6782099767138424	[521]	[799,764,731,723]	9	hSpCas9	negative selection	7629523
20234796	20234819	X	-	27260156	LNCAPCLONEFGC	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.2905013734739639	[276]	[263,213,344,416]	4	hSpCas9	negative selection	7629524
20195104	20195127	X	-	27260156	LNCAPCLONEFGC	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.045194369316601646	[378]	[300,314,526,302]	0	hSpCas9	negative selection	7693775
20234768	20234791	X	+	27260156	LNCAPCLONEFGC	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.2836724178791803	[1435]	[1671,1524,1664,1484]	4	hSpCas9	negative selection	7693776
20195067	20195090	X	+	27260156	LNCAPCLONEFGC	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.000824125464692016	[405]	[490,352,365,259]	0	hSpCas9	negative selection	7693777
20195129	20195152	X	-	27260156	PANC0327	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.33279505594486114	[731]	[547,465,483,575]	-5	hSpCas9	negative selection	7750773
20209359	20209382	X	-	27260156	PANC0327	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.6848558120776971	[521]	[633,842,874,607]	8	hSpCas9	negative selection	7750774
20234796	20234819	X	-	27260156	PANC0327	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.18177643155732925	[276]	[293,235,241,350]	2	hSpCas9	negative selection	7750775
20195104	20195127	X	-	27260156	PANC0327	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.05301693257003981	[378]	[293,187,329,500]	-1	hSpCas9	negative selection	7815026
20234768	20234791	X	+	27260156	PANC0327	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.19003575927168614	[1435]	[1535,936,1054,1001]	-3	hSpCas9	negative selection	7815027
20195067	20195090	X	+	27260156	PANC0327	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.6180504873231615	[405]	[432,455,335,990]	8	hSpCas9	negative selection	7815028
20195129	20195152	X	-	27260156	NCIH2009	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.025961190833433845	[731]	[1043,910,1169]	0	hSpCas9	negative selection	7872024
20209359	20209382	X	-	27260156	NCIH2009	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.6823869464234502	[521]	[1213,1050,1254]	8	hSpCas9	negative selection	7872025
20234796	20234819	X	-	27260156	NCIH2009	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.5155363439147524	[276]	[584,501,578]	7	hSpCas9	negative selection	7872026
20195104	20195127	X	-	27260156	NCIH2009	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.6080843590772332	[378]	[562,249,272]	-6	hSpCas9	negative selection	7936277
20234768	20234791	X	+	27260156	NCIH2009	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.09482127703012289	[1435]	[1901,2015,1716]	-1	hSpCas9	negative selection	7936278
20195067	20195090	X	+	27260156	NCIH2009	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.5577542257895678	[405]	[1095,784,674]	7	hSpCas9	negative selection	7936279
20195129	20195152	X	-	27260156	NCIH1373	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.30614320488660907	[731]	[1138,747,871,358]	3	hSpCas9	negative selection	7993275
20209359	20209382	X	-	27260156	NCIH1373	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.67098421670405	[521]	[1254,579,994,257]	6	hSpCas9	negative selection	7993276
20234796	20234819	X	-	27260156	NCIH1373	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.4781414524808559	[276]	[875,292,206,115]	5	hSpCas9	negative selection	7993277
20195104	20195127	X	-	27260156	NCIH1373	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.7969719490504087	[378]	[311,276,250,35]	-7	hSpCas9	negative selection	8057528
20234768	20234791	X	+	27260156	NCIH1373	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	-0.12363223655407718	[1435]	[1669,966,1707,432]	-1	hSpCas9	negative selection	8057529
20195067	20195090	X	+	27260156	NCIH1373	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	1.086405562159323	[405]	[1673,461,888,263]	9	hSpCas9	negative selection	8057530
20195129	20195152	X	-	27260156	PATU8902	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.27939816774109383	[731]	[818,1078,791,2523]	3	hSpCas9	negative selection	8114526
20209359	20209382	X	-	27260156	PATU8902	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	1.013404127891561	[521]	[1140,1482,1666,1526]	9	hSpCas9	negative selection	8114527
20234796	20234819	X	-	27260156	PATU8902	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	1.0241051677680857	[276]	[907,497,833,888]	9	hSpCas9	negative selection	8114528
20195104	20195127	X	-	27260156	PATU8902	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.17854954170001924	[378]	[427,849,337,871]	1	hSpCas9	negative selection	8178779
20234768	20234791	X	+	27260156	PATU8902	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.7130927378020424	[1435]	[3663,3360,2746,3471]	7	hSpCas9	negative selection	8178780
20195067	20195090	X	+	27260156	PATU8902	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.3053240069902808	[405]	[1208,576,460,582]	3	hSpCas9	negative selection	8178781
20195129	20195152	X	-	27260156	PANC1	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.09368533580516725	[731]	[486,826,611,488]	-1	hSpCas9	negative selection	8235777
20209359	20209382	X	-	27260156	PANC1	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.21247179265227528	[521]	[529,869,314,437]	3	hSpCas9	negative selection	8235778
20234796	20234819	X	-	27260156	PANC1	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.4435612698958837	[276]	[362,344,307,282]	7	hSpCas9	negative selection	8235779
20195104	20195127	X	-	27260156	PANC1	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.1296010956615262	[378]	[259,386,387,386]	2	hSpCas9	negative selection	8300030
20234768	20234791	X	+	27260156	PANC1	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.04247768725055834	[1435]	[1304,1265,1404,1109]	0	hSpCas9	negative selection	8300031
20195067	20195090	X	+	27260156	PANC1	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.5455494793961714	[405]	[487,745,516,351]	8	hSpCas9	negative selection	8300032
20195129	20195152	X	-	27260156	PANC0813	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.22261874503765045	[731]	[744,648,1047,518]	-4	hSpCas9	negative selection	8357028
20209359	20209382	X	-	27260156	PANC0813	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.4867020806900484	[521]	[1031,647,814,950]	7	hSpCas9	negative selection	8357029
20234796	20234819	X	-	27260156	PANC0813	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.516975419614273	[276]	[381,603,444,424]	8	hSpCas9	negative selection	8357030
20195104	20195127	X	-	27260156	PANC0813	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.39538934062067965	[378]	[445,294,368,257]	-6	hSpCas9	negative selection	8421281
20234768	20234791	X	+	27260156	PANC0813	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.11065627477032103	[1435]	[1669,1940,1955,1707]	1	hSpCas9	negative selection	8421282
20195067	20195090	X	+	27260156	PANC0813	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.2407795431735615	[405]	[671,480,663,452]	4	hSpCas9	negative selection	8421283
20195129	20195152	X	-	27260156	RDES	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.13158305516881674	[731]	[877,747,1082,992]	2	hSpCas9	negative selection	8478279
20209359	20209382	X	-	27260156	RDES	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.4828646324782617	[521]	[625,861,777,1154]	7	hSpCas9	negative selection	8478280
20234796	20234819	X	-	27260156	RDES	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.3303856066683599	[276]	[366,323,497,421]	5	hSpCas9	negative selection	8478281
20195104	20195127	X	-	27260156	RDES	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.038796682500097546	[378]	[337,465,525,476]	0	hSpCas9	negative selection	8542532
20234768	20234791	X	+	27260156	RDES	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.24839260160319054	[1435]	[1627,1781,2039,2513]	4	hSpCas9	negative selection	8542533
20195067	20195090	X	+	27260156	RDES	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.148990626452153	[405]	[353,590,553,598]	2	hSpCas9	negative selection	8542534
20195129	20195152	X	-	27260156	PC3	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.015064451183777194	[731]	[547,605,1344,627]	0	hSpCas9	negative selection	8599530
20209359	20209382	X	-	27260156	PC3	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	-0.17152768784519595	[521]	[281,344,1131,389]	-4	hSpCas9	negative selection	8599531
20234796	20234819	X	-	27260156	PC3	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.09827718805985297	[276]	[287,231,455,229]	2	hSpCas9	negative selection	8599532
20195104	20195127	X	-	27260156	PC3	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.022902343883292597	[378]	[248,378,581,373]	0	hSpCas9	negative selection	8663783
20234768	20234791	X	+	27260156	PC3	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.07360391850025572	[1435]	[938,1469,2297,1740]	1	hSpCas9	negative selection	8663784
20195067	20195090	X	+	27260156	PC3	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.005440161474756816	[405]	[318,407,446,444]	0	hSpCas9	negative selection	8663785
20195129	20195152	X	-	27260156	PATU8988T	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.12538683235943027	[731]	[547,693,795,549]	-2	hSpCas9	negative selection	8720781
20209359	20209382	X	-	27260156	PATU8988T	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.5931055470973614	[521]	[548,1082,707,731]	8	hSpCas9	negative selection	8720782
20234796	20234819	X	-	27260156	PATU8988T	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	1.0771593768571919	[276]	[356,612,277,1058]	9	hSpCas9	negative selection	8720783
20195104	20195127	X	-	27260156	PATU8988T	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.47010468114291604	[378]	[301,266,256,228]	-6	hSpCas9	negative selection	8785034
20234768	20234791	X	+	27260156	PATU8988T	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.026573519409127888	[1435]	[1383,1438,1200,1653]	0	hSpCas9	negative selection	8785035
20195067	20195090	X	+	27260156	PATU8988T	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.10385294219010359	[405]	[561,515,298,310]	1	hSpCas9	negative selection	8785036
20195129	20195152	X	-	27260156	T47D	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.12880252158698047	[731]	[733,735,742,914]	-3	hSpCas9	negative selection	8842032
20209359	20209382	X	-	27260156	T47D	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.455007365264799	[521]	[870,777,851,837]	8	hSpCas9	negative selection	8842033
20234796	20234819	X	-	27260156	T47D	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.12617660506569484	[276]	[404,313,348,343]	2	hSpCas9	negative selection	8842034
20195104	20195127	X	-	27260156	T47D	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.20062832528895574	[378]	[565,508,457,496]	4	hSpCas9	negative selection	8906285
20234768	20234791	X	+	27260156	T47D	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.14073902108690306	[1435]	[1868,1872,1711,1924]	3	hSpCas9	negative selection	8906286
20195067	20195090	X	+	27260156	T47D	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.26980898972144396	[405]	[576,475,675,557]	6	hSpCas9	negative selection	8906287
20195129	20195152	X	-	27260156	SU8686	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.13009244950968102	[731]	[472,589,800,848]	-2	hSpCas9	negative selection	8963283
20209359	20209382	X	-	27260156	SU8686	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.6689121411759938	[521]	[649,743,757,1226]	9	hSpCas9	negative selection	8963284
20234796	20234819	X	-	27260156	SU8686	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.24932737881284228	[276]	[268,260,361,446]	4	hSpCas9	negative selection	8963285
20195104	20195127	X	-	27260156	SU8686	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.840144560377667	[378]	[198,170,202,282]	-8	hSpCas9	negative selection	9027536
20234768	20234791	X	+	27260156	SU8686	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.18287841109784453	[1435]	[1491,1598,1571,1840]	3	hSpCas9	negative selection	9027537
20195067	20195090	X	+	27260156	SU8686	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.18426280131119765	[405]	[368,473,492,506]	3	hSpCas9	negative selection	9027538
20195129	20195152	X	-	27260156	SKES1	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.09658637363117006	[731]	[870,699,563,625]	-2	hSpCas9	negative selection	9084534
20209359	20209382	X	-	27260156	SKES1	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.03030500519213794	[521]	[565,466,531,550]	0	hSpCas9	negative selection	9084535
20234796	20234819	X	-	27260156	SKES1	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.13003607939147077	[276]	[307,284,237,366]	3	hSpCas9	negative selection	9084536
20195104	20195127	X	-	27260156	SKES1	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.06164806549666735	[378]	[493,442,279,379]	1	hSpCas9	negative selection	9148787
20234768	20234791	X	+	27260156	SKES1	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.192313334812928	[1435]	[1787,1890,1530,1400]	4	hSpCas9	negative selection	9148788
20195067	20195090	X	+	27260156	SKES1	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.06369412763032403	[405]	[588,410,382,337]	1	hSpCas9	negative selection	9148789
20195129	20195152	X	-	27260156	TOV112D	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.17024800194074907	[731]	[1151,942,758,509]	3	hSpCas9	negative selection	9205785
20209359	20209382	X	-	27260156	TOV112D	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.22786886594950279	[521]	[557,898,660,401]	4	hSpCas9	negative selection	9205786
20234796	20234819	X	-	27260156	TOV112D	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.3714557208711512	[276]	[355,313,332,418]	7	hSpCas9	negative selection	9205787
20195104	20195127	X	-	27260156	TOV112D	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.12921444904247906	[378]	[289,594,369,437]	2	hSpCas9	negative selection	9270038
20234768	20234791	X	+	27260156	TOV112D	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.20181326336025784	[1435]	[2053,2022,1392,1278]	4	hSpCas9	negative selection	9270039
20195067	20195090	X	+	27260156	TOV112D	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	-0.020695192606747848	[405]	[385,472,460,301]	0	hSpCas9	negative selection	9270040
20195129	20195152	X	-	27260156	TC71	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	-0.20460822037226734	[731]	[767,597,692,660]	-5	hSpCas9	negative selection	9327036
20209359	20209382	X	-	27260156	TC71	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.2482263238620459	[521]	[605,746,596,714]	6	hSpCas9	negative selection	9327037
20234796	20234819	X	-	27260156	TC71	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.11039645650436314	[276]	[353,271,283,375]	3	hSpCas9	negative selection	9327038
20195104	20195127	X	-	27260156	TC71	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	-0.08671926585344941	[378]	[383,385,420,334]	-2	hSpCas9	negative selection	9391289
20234768	20234791	X	+	27260156	TC71	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.2840864557380989	[1435]	[1876,1823,1855,1944]	7	hSpCas9	negative selection	9391290
20195067	20195090	X	+	27260156	TC71	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.2503276449083809	[405]	[477,414,645,528]	6	hSpCas9	negative selection	9391291
20195129	20195152	X	-	27260156	TC32	viability	TTATAGTTCGAGACCGAGTTCGG	RPS6KA3	ENSG00000177189	0.16520647991664295	[731]	[614,538,998,1051]	3	hSpCas9	negative selection	9448287
20209359	20209382	X	-	27260156	TC32	viability	TGCAATCACACATCATGTAAAGG	RPS6KA3	ENSG00000177189	0.5514688522839158	[521]	[702,609,894,694]	8	hSpCas9	negative selection	9448288
20234796	20234819	X	-	27260156	TC32	viability	ACAGAATGGACAGCAAATTATGG	RPS6KA3	ENSG00000177189	0.33119168355566614	[276]	[304,172,361,530]	6	hSpCas9	negative selection	9448289
20195104	20195127	X	-	27260156	TC32	viability	AAAAATGGAACGTGATATCTTGG	RPS6KA3	ENSG00000177189	0.06609242047221386	[378]	[379,189,567,438]	1	hSpCas9	negative selection	9512540
20234768	20234791	X	+	27260156	TC32	viability	TTAATCTCCTCCTCTCCCATAGG	RPS6KA3	ENSG00000177189	0.03571530352281704	[1435]	[1329,1018,1754,1565]	0	hSpCas9	negative selection	9512541
20195067	20195090	X	+	27260156	TC32	viability	TAATGCAACTTGACAATAAAAGG	RPS6KA3	ENSG00000177189	0.36709748996037395	[405]	[445,338,710,548]	6	hSpCas9	negative selection	9512542
20155433	20155456	X	+	27869803	HPAFII	viability after 27 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.8570420461579568	[663]	[225,164,NaN]	-6	hSpCas9	negative selection	9608427
20156163	20156186	X	-	27869803	HPAFII	viability after 27 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	0.65401538104974	[39]	[1,58,NaN]	5	hSpCas9	negative selection	9608428
20161721	20161744	X	-	27869803	HPAFII	viability after 27 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.23383568931855958	[437]	[197,193,NaN]	-2	hSpCas9	negative selection	9608429
20167622	20167645	X	+	27869803	HPAFII	viability after 27 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	0.0788214555654573	[240]	[117,146,NaN]	0	hSpCas9	negative selection	9608430
20266559	20266582	X	+	27869803	HPAFII	viability after 27 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.4186063574083985	[198]	[140,25,NaN]	-3	hSpCas9	negative selection	9608431
20266593	20266616	X	-	27869803	HPAFII	viability after 27 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.16082851984606183	[155]	[92,56,NaN]	-1	hSpCas9	negative selection	9608432
20155433	20155456	X	+	27869803	HPAFII	viability after 15 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.6186505581722656	[663]	[465,463,NaN]	-6	hSpCas9	negative selection	9690876
20156163	20156186	X	-	27869803	HPAFII	viability after 15 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	0.5664304906068165	[39]	[1,101,NaN]	6	hSpCas9	negative selection	9690877
20161721	20161744	X	-	27869803	HPAFII	viability after 15 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.3024806583478713	[437]	[340,406,NaN]	-3	hSpCas9	negative selection	9690878
20167622	20167645	X	+	27869803	HPAFII	viability after 15 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.3389759267355359	[240]	[279,157,NaN]	-4	hSpCas9	negative selection	9690879
20266559	20266582	X	+	27869803	HPAFII	viability after 15 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-1.0054346168302366	[198]	[108,104,NaN]	-7	hSpCas9	negative selection	9690880
20266593	20266616	X	-	27869803	HPAFII	viability after 15 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.7114529697347624	[155]	[432,175,NaN]	7	hSpCas9	negative selection	9690881
20155433	20155456	X	+	27869803	ASPC1	viability after 36 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.648791139263531	[1294]	[450,120,303]	-6	hSpCas9	negative selection	9773325
20156163	20156186	X	-	27869803	ASPC1	viability after 36 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.898449418135227	[57]	[41,413,16]	9	hSpCas9	negative selection	9773326
20161721	20161744	X	-	27869803	ASPC1	viability after 36 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.3974816780918621	[993]	[201,315,261]	-4	hSpCas9	negative selection	9773327
20167622	20167645	X	+	27869803	ASPC1	viability after 36 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.8277182060715591	[630]	[112,47,190]	-7	hSpCas9	negative selection	9773328
20266559	20266582	X	+	27869803	ASPC1	viability after 36 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.3129396603894919	[505]	[266,208,191]	3	hSpCas9	negative selection	9773329
20266593	20266616	X	-	27869803	ASPC1	viability after 36 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.05167025584193702	[504]	[71,210,235]	0	hSpCas9	negative selection	9773330
20155433	20155456	X	+	27869803	PATU8988S	viability after 35 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.23467919808290466	[859]	[235,352,NaN]	-2	hSpCas9	negative selection	9855774
20156163	20156186	X	-	27869803	PATU8988S	viability after 35 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.0726681251926147	[84]	[147,139,NaN]	9	hSpCas9	negative selection	9855775
20161721	20161744	X	-	27869803	PATU8988S	viability after 35 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	0.08879189505389351	[1001]	[504,352,NaN]	1	hSpCas9	negative selection	9855776
20167622	20167645	X	+	27869803	PATU8988S	viability after 35 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.9921115529153808	[429]	[115,57,NaN]	-7	hSpCas9	negative selection	9855777
20266559	20266582	X	+	27869803	PATU8988S	viability after 35 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	0.3085578969271215	[371]	[207,162,NaN]	3	hSpCas9	negative selection	9855778
20266593	20266616	X	-	27869803	PATU8988S	viability after 35 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.37222483340904033	[446]	[241,223,NaN]	4	hSpCas9	negative selection	9855779
20155433	20155456	X	+	27869803	PATU8988S	viability after 31 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.08015010622932639	[859]	[264,399,NaN]	-1	hSpCas9	negative selection	9938223
20156163	20156186	X	-	27869803	PATU8988S	viability after 31 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	2.039754608024396	[84]	[141,135,NaN]	9	hSpCas9	negative selection	9938224
20161721	20161744	X	-	27869803	PATU8988S	viability after 31 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.22364897080989632	[1001]	[368,307,NaN]	-3	hSpCas9	negative selection	9938225
20167622	20167645	X	+	27869803	PATU8988S	viability after 31 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.3816751773993591	[429]	[146,111,NaN]	-4	hSpCas9	negative selection	9938226
20266559	20266582	X	+	27869803	PATU8988S	viability after 31 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.13004772550588617	[371]	[69,218,NaN]	-1	hSpCas9	negative selection	9938227
20266593	20266616	X	-	27869803	PATU8988S	viability after 31 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.20093830534849	[446]	[181,233,NaN]	2	hSpCas9	negative selection	9938228
20155433	20155456	X	+	27869803	HPAFII	viability after 35 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-0.7916571995542253	[663]	[212,172,NaN]	-4	hSpCas9	negative selection	10020672
20156163	20156186	X	-	27869803	HPAFII	viability after 35 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-0.17531017223425271	[39]	[0,36,NaN]	-1	hSpCas9	negative selection	10020673
20161721	20161744	X	-	27869803	HPAFII	viability after 35 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.7910511114247104	[437]	[66,196,NaN]	-4	hSpCas9	negative selection	10020674
20167622	20167645	X	+	27869803	HPAFII	viability after 35 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	0.18567674042549853	[240]	[134,142,NaN]	1	hSpCas9	negative selection	10020675
20266559	20266582	X	+	27869803	HPAFII	viability after 35 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.9455680780244962	[198]	[80,19,NaN]	-5	hSpCas9	negative selection	10020676
20266593	20266616	X	-	27869803	HPAFII	viability after 35 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	-0.049844519185988756	[155]	[72,79,NaN]	0	hSpCas9	negative selection	10020677
20155433	20155456	X	+	27869803	HPAFII	viability after 31 days	TCCGCTGAGCAAGAGTAGAGCGG	RPS6KA3	ENSG00000177189	-1.0132420290023412	[663]	[231,132,NaN]	-6	hSpCas9	negative selection	10103121
20156163	20156186	X	-	27869803	HPAFII	viability after 31 days	GACATCCTTGGATCGTCCACTGG	RPS6KA3	ENSG00000177189	-0.33880977570742266	[39]	[0,35,NaN]	-2	hSpCas9	negative selection	10103122
20161721	20161744	X	-	27869803	HPAFII	viability after 31 days	TGGTCCTGATGATACACCAGAGG	RPS6KA3	ENSG00000177189	-0.4298326127823159	[437]	[114,255,NaN]	-3	hSpCas9	negative selection	10103123
20167622	20167645	X	+	27869803	HPAFII	viability after 31 days	TATAGTGAACAGGACAGCACTGG	RPS6KA3	ENSG00000177189	-0.16851143247395348	[240]	[60,184,NaN]	-1	hSpCas9	negative selection	10103124
20266559	20266582	X	+	27869803	HPAFII	viability after 31 days	CTCACCTCAGCGCTGTCGGACGG	RPS6KA3	ENSG00000177189	-0.8876300887172706	[198]	[101,14,NaN]	-5	hSpCas9	negative selection	10103125
20266593	20266616	X	-	27869803	HPAFII	viability after 31 days	GGCGGACCCGTGGCAGAAGATGG	RPS6KA3	ENSG00000177189	0.4526251045944302	[155]	[137,99,NaN]	3	hSpCas9	negative selection	10103126
20266611	20266634	X	-	28162770	P31FUJ	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.33689353965346713	[94]	[140]	3	hSpCas9	negative selection	10228091
20195098	20195121	X	-	28162770	P31FUJ	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.35125093917557426	[528]	[792]	4	hSpCas9	negative selection	10228092
20234775	20234798	X	-	28162770	P31FUJ	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.8748385187735909	[70]	[152]	8	hSpCas9	negative selection	10228093
20161675	20161698	X	-	28162770	P31FUJ	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.19604109438949568	[181]	[244]	2	hSpCas9	negative selection	10228094
20156108	20156131	X	-	28162770	P31FUJ	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.06064351431550952	[398]	[488]	0	hSpCas9	negative selection	10228095
20266563	20266586	X	-	28162770	P31FUJ	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.5224438649289869	[297]	[502]	6	hSpCas9	negative selection	10228096
20172782	20172805	X	+	28162770	P31FUJ	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.45655550824477403	[190]	[307]	5	hSpCas9	negative selection	10228097
20156197	20156220	X	+	28162770	P31FUJ	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.15462306365660528	[632]	[827]	1	hSpCas9	negative selection	10228098
20266587	20266610	X	-	28162770	P31FUJ	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.8178238686555894	[27]	[57]	8	hSpCas9	negative selection	10228099
20204011	20204034	X	+	28162770	P31FUJ	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.12343513850507759	[481]	[616]	1	hSpCas9	negative selection	10228100
20266611	20266634	X	-	28162770	TF1	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10397457
20195098	20195121	X	-	28162770	TF1	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[417]	1	hSpCas9	negative selection	10397458
20234775	20234798	X	-	28162770	TF1	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10397459
20161675	20161698	X	-	28162770	TF1	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10397460
20156108	20156131	X	-	28162770	TF1	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[880]	1	hSpCas9	negative selection	10397461
20266563	20266586	X	-	28162770	TF1	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[395]	1	hSpCas9	negative selection	10397462
20172782	20172805	X	+	28162770	TF1	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10397463
20156197	20156220	X	+	28162770	TF1	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[378]	1	hSpCas9	negative selection	10397464
20266587	20266610	X	-	28162770	TF1	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10397465
20204011	20204034	X	+	28162770	TF1	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	NaN	[NaN]	[895]	1	hSpCas9	negative selection	10397466
20266611	20266634	X	-	28162770	SKM1	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.4734541855041656	[21]	[53]	4	hSpCas9	negative selection	10566823
20195098	20195121	X	-	28162770	SKM1	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-1.4773535266345597	[125]	[79]	-7	hSpCas9	negative selection	10566824
20234775	20234798	X	-	28162770	SKM1	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-1.2225396276057343	[32]	[24]	-7	hSpCas9	negative selection	10566825
20161675	20161698	X	-	28162770	SKM1	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	-1.2788593729954765	[69]	[50]	-7	hSpCas9	negative selection	10566826
20156108	20156131	X	-	28162770	SKM1	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	-0.6170199602343769	[130]	[150]	-5	hSpCas9	negative selection	10566827
20266563	20266586	X	-	28162770	SKM1	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	-0.07704331310226875	[107]	[180]	0	hSpCas9	negative selection	10566828
20172782	20172805	X	+	28162770	SKM1	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-1.4500329206350477	[50]	[32]	-7	hSpCas9	negative selection	10566829
20156197	20156220	X	+	28162770	SKM1	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.5917040786002113	[155]	[182]	-5	hSpCas9	negative selection	10566830
20266587	20266610	X	-	28162770	SKM1	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.9149638961442006	[8]	[29]	8	hSpCas9	negative selection	10566831
20204011	20204034	X	+	28162770	SKM1	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	-0.8220016980220055	[104]	[104]	-6	hSpCas9	negative selection	10566832
20266611	20266634	X	-	28162770	SKM1	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.4734541855041656	[21]	[53]	4	hSpCas9	negative selection	10736189
20195098	20195121	X	-	28162770	SKM1	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-1.4773535266345597	[125]	[79]	-7	hSpCas9	negative selection	10736190
20234775	20234798	X	-	28162770	SKM1	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-1.2225396276057343	[32]	[24]	-7	hSpCas9	negative selection	10736191
20161675	20161698	X	-	28162770	SKM1	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	-1.2788593729954765	[69]	[50]	-7	hSpCas9	negative selection	10736192
20156108	20156131	X	-	28162770	SKM1	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	-0.6170199602343769	[130]	[150]	-5	hSpCas9	negative selection	10736193
20266563	20266586	X	-	28162770	SKM1	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	-0.07704331310226875	[107]	[180]	0	hSpCas9	negative selection	10736194
20172782	20172805	X	+	28162770	SKM1	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-1.4500329206350477	[50]	[32]	-7	hSpCas9	negative selection	10736195
20156197	20156220	X	+	28162770	SKM1	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.5917040786002113	[155]	[182]	-5	hSpCas9	negative selection	10736196
20266587	20266610	X	-	28162770	SKM1	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.9149638961442006	[8]	[29]	8	hSpCas9	negative selection	10736197
20204011	20204034	X	+	28162770	SKM1	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	-0.8220016980220055	[104]	[104]	-6	hSpCas9	negative selection	10736198
20266611	20266634	X	-	28162770	PL21	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	-0.030158004932473892	[60]	[25]	0	hSpCas9	negative selection	10905555
20195098	20195121	X	-	28162770	PL21	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.058920196757511256	[310]	[140]	0	hSpCas9	negative selection	10905556
20234775	20234798	X	-	28162770	PL21	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.2810596098728876	[103]	[54]	2	hSpCas9	negative selection	10905557
20161675	20161698	X	-	28162770	PL21	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.30907398604248415	[203]	[109]	2	hSpCas9	negative selection	10905558
20156108	20156131	X	-	28162770	PL21	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.9669968077839219	[448]	[381]	7	hSpCas9	negative selection	10905559
20266563	20266586	X	-	28162770	PL21	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.010196719470050408	[380]	[166]	0	hSpCas9	negative selection	10905560
20172782	20172805	X	+	28162770	PL21	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.48459300395801963	[155]	[94]	4	hSpCas9	negative selection	10905561
20156197	20156220	X	+	28162770	PL21	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.6325117247734409	[454]	[306]	5	hSpCas9	negative selection	10905562
20266587	20266610	X	-	28162770	PL21	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	1.9106329972943352	[21]	[35]	9	hSpCas9	negative selection	10905563
20204011	20204034	X	+	28162770	PL21	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	1.2398658928049306	[393]	[404]	8	hSpCas9	negative selection	10905564
20266611	20266634	X	-	28162770	P31FUJ	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.33689353965346713	[94]	[140]	3	hSpCas9	negative selection	11074921
20195098	20195121	X	-	28162770	P31FUJ	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.35125093917557426	[528]	[792]	4	hSpCas9	negative selection	11074922
20234775	20234798	X	-	28162770	P31FUJ	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.8748385187735909	[70]	[152]	8	hSpCas9	negative selection	11074923
20161675	20161698	X	-	28162770	P31FUJ	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.19604109438949568	[181]	[244]	2	hSpCas9	negative selection	11074924
20156108	20156131	X	-	28162770	P31FUJ	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.06064351431550952	[398]	[488]	0	hSpCas9	negative selection	11074925
20266563	20266586	X	-	28162770	P31FUJ	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.5224438649289869	[297]	[502]	6	hSpCas9	negative selection	11074926
20172782	20172805	X	+	28162770	P31FUJ	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.45655550824477403	[190]	[307]	5	hSpCas9	negative selection	11074927
20156197	20156220	X	+	28162770	P31FUJ	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.15462306365660528	[632]	[827]	1	hSpCas9	negative selection	11074928
20266587	20266610	X	-	28162770	P31FUJ	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.8178238686555894	[27]	[57]	8	hSpCas9	negative selection	11074929
20204011	20204034	X	+	28162770	P31FUJ	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.12343513850507759	[481]	[616]	1	hSpCas9	negative selection	11074930
20266611	20266634	X	-	28162770	OCIAML5	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	-0.2443839936427572	[41]	[63]	-2	hSpCas9	negative selection	11244287
20195098	20195121	X	-	28162770	OCIAML5	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.9853054951538269	[264]	[946]	8	hSpCas9	negative selection	11244288
20234775	20234798	X	-	28162770	OCIAML5	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-0.7971001116460683	[102]	[106]	-5	hSpCas9	negative selection	11244289
20161675	20161698	X	-	28162770	OCIAML5	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	-0.573165759571182	[210]	[255]	-4	hSpCas9	negative selection	11244290
20156108	20156131	X	-	28162770	OCIAML5	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.5821432376896929	[298]	[807]	5	hSpCas9	negative selection	11244291
20266563	20266586	X	-	28162770	OCIAML5	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.6016513965789065	[183]	[503]	5	hSpCas9	negative selection	11244292
20172782	20172805	X	+	28162770	OCIAML5	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-0.1201719662452127	[170]	[283]	-1	hSpCas9	negative selection	11244293
20156197	20156220	X	+	28162770	OCIAML5	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.3482778264561692	[291]	[670]	3	hSpCas9	negative selection	11244294
20266587	20266610	X	-	28162770	OCIAML5	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.6813656292170773	[18]	[54]	6	hSpCas9	negative selection	11244295
20204011	20204034	X	+	28162770	OCIAML5	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	1.18021671102954	[231]	[948]	8	hSpCas9	negative selection	11244296
20266611	20266634	X	-	28162770	EOL1	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	-1.4164891462645324	[151]	[29]	-7	hSpCas9	negative selection	11413653
20195098	20195121	X	-	28162770	EOL1	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.3846190244638821	[614]	[422]	3	hSpCas9	negative selection	11413654
20234775	20234798	X	-	28162770	EOL1	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-0.9430019324058161	[207]	[56]	-6	hSpCas9	negative selection	11413655
20161675	20161698	X	-	28162770	EOL1	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	-0.17075918852519284	[437]	[204]	-1	hSpCas9	negative selection	11413656
20156108	20156131	X	-	28162770	EOL1	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.7303901702945372	[817]	[714]	6	hSpCas9	negative selection	11413657
20266563	20266586	X	-	28162770	EOL1	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.5224493279991889	[665]	[503]	5	hSpCas9	negative selection	11413658
20172782	20172805	X	+	28162770	EOL1	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.35493323518281433	[186]	[125]	3	hSpCas9	negative selection	11413659
20156197	20156220	X	+	28162770	EOL1	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	0.429882737544955	[657]	[466]	4	hSpCas9	negative selection	11413660
20266587	20266610	X	-	28162770	EOL1	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	-2.0754522284294654	[63]	[7]	-8	hSpCas9	negative selection	11413661
20204011	20204034	X	+	28162770	EOL1	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.021726840271062975	[530]	[283]	0	hSpCas9	negative selection	11413662
20266611	20266634	X	-	28162770	MOLM13	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	1.7850004601341654	[119]	[298]	9	hSpCas9	negative selection	11583019
20195098	20195121	X	-	28162770	MOLM13	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.31419284189415264	[662]	[595]	2	hSpCas9	negative selection	11583020
20234775	20234798	X	-	28162770	MOLM13	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.6447671436286581	[137]	[155]	5	hSpCas9	negative selection	11583021
20161675	20161698	X	-	28162770	MOLM13	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.37642033553435283	[292]	[274]	2	hSpCas9	negative selection	11583022
20156108	20156131	X	-	28162770	MOLM13	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.7683191933389335	[621]	[765]	6	hSpCas9	negative selection	11583023
20266563	20266586	X	-	28162770	MOLM13	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	1.2664643896715633	[517]	[900]	8	hSpCas9	negative selection	11583024
20172782	20172805	X	+	28162770	MOLM13	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.4328424344453782	[249]	[243]	3	hSpCas9	negative selection	11583025
20156197	20156220	X	+	28162770	MOLM13	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.8793815614572469	[803]	[315]	-5	hSpCas9	negative selection	11583026
20266587	20266610	X	-	28162770	MOLM13	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	1.2497092114950454	[56]	[97]	8	hSpCas9	negative selection	11583027
20204011	20204034	X	+	28162770	MOLM13	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.31641874613874843	[601]	[541]	2	hSpCas9	negative selection	11583028
20266611	20266634	X	-	28162770	HEL	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.572349504108959	[104]	[99]	5	hSpCas9	negative selection	11752385
20195098	20195121	X	-	28162770	HEL	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.053747692810778847	[409]	[252]	0	hSpCas9	negative selection	11752386
20234775	20234798	X	-	28162770	HEL	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.9936459938594853	[137]	[175]	8	hSpCas9	negative selection	11752387
20161675	20161698	X	-	28162770	HEL	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.18746740791883765	[302]	[220]	1	hSpCas9	negative selection	11752388
20156108	20156131	X	-	28162770	HEL	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.7956769190237512	[616]	[685]	7	hSpCas9	negative selection	11752389
20266563	20266586	X	-	28162770	HEL	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.9646669268877193	[487]	[609]	8	hSpCas9	negative selection	11752390
20172782	20172805	X	+	28162770	HEL	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.9940289865190624	[213]	[272]	8	hSpCas9	negative selection	11752391
20156197	20156220	X	+	28162770	HEL	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.3307447232205678	[592]	[301]	-2	hSpCas9	negative selection	11752392
20266587	20266610	X	-	28162770	HEL	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	-2.3114574783865183	[30]	[3]	-8	hSpCas9	negative selection	11752393
20204011	20204034	X	+	28162770	HEL	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.8357750432082335	[460]	[526]	7	hSpCas9	negative selection	11752394
20266611	20266634	X	-	28162770	MV411	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	-0.15310037880095329	[98]	[74]	-1	hSpCas9	negative selection	11921751
20195098	20195121	X	-	28162770	MV411	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.7920423138877907	[289]	[422]	7	hSpCas9	negative selection	11921752
20234775	20234798	X	-	28162770	MV411	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	0.8324000515039314	[89]	[134]	7	hSpCas9	negative selection	11921753
20161675	20161698	X	-	28162770	MV411	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.5786434592581484	[185]	[233]	5	hSpCas9	negative selection	11921754
20156108	20156131	X	-	28162770	MV411	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.2267286539506661	[420]	[414]	2	hSpCas9	negative selection	11921755
20266563	20266586	X	-	28162770	MV411	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.7039701113794589	[316]	[434]	6	hSpCas9	negative selection	11921756
20172782	20172805	X	+	28162770	MV411	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	1.2329379810876602	[149]	[296]	9	hSpCas9	negative selection	11921757
20156197	20156220	X	+	28162770	MV411	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.4701627185164998	[443]	[269]	-3	hSpCas9	negative selection	11921758
20266587	20266610	X	-	28162770	MV411	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	-1.4588312461605146	[61]	[18]	-7	hSpCas9	negative selection	11921759
20204011	20204034	X	+	28162770	MV411	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.2154651610444953	[364]	[356]	1	hSpCas9	negative selection	11921760
20266611	20266634	X	-	28162770	MONOMAC1	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.41594002983119904	[50]	[77]	4	hSpCas9	negative selection	12091117
20195098	20195121	X	-	28162770	MONOMAC1	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.3413830677245723	[209]	[304]	3	hSpCas9	negative selection	12091118
20234775	20234798	X	-	28162770	MONOMAC1	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-0.38344997129043523	[65]	[57]	-3	hSpCas9	negative selection	12091119
20161675	20161698	X	-	28162770	MONOMAC1	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.8593011370902583	[112]	[234]	7	hSpCas9	negative selection	12091120
20156108	20156131	X	-	28162770	MONOMAC1	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.52267506577484	[285]	[470]	5	hSpCas9	negative selection	12091121
20266563	20266586	X	-	28162770	MONOMAC1	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.2029567719948402	[240]	[317]	2	hSpCas9	negative selection	12091122
20172782	20172805	X	+	28162770	MONOMAC1	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-0.2145242737883949	[82]	[81]	-2	hSpCas9	negative selection	12091123
20156197	20156220	X	+	28162770	MONOMAC1	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.6529822899186034	[309]	[225]	-5	hSpCas9	negative selection	12091124
20266587	20266610	X	-	28162770	MONOMAC1	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	0.5228552337477108	[16]	[27]	5	hSpCas9	negative selection	12091125
20204011	20204034	X	+	28162770	MONOMAC1	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.25853213194534486	[271]	[372]	2	hSpCas9	negative selection	12091126
20266611	20266634	X	-	28162770	OCIAML2	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	0.47690275486370315	[13]	[107]	4	hSpCas9	negative selection	12260483
20195098	20195121	X	-	28162770	OCIAML2	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	0.4292743400502502	[68]	[514]	4	hSpCas9	negative selection	12260484
20234775	20234798	X	-	28162770	OCIAML2	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	1.205831029964491	[13]	[178]	9	hSpCas9	negative selection	12260485
20161675	20161698	X	-	28162770	OCIAML2	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	0.229809892898931	[45]	[298]	2	hSpCas9	negative selection	12260486
20156108	20156131	X	-	28162770	OCIAML2	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	0.16558437520269131	[105]	[658]	1	hSpCas9	negative selection	12260487
20266563	20266586	X	-	28162770	OCIAML2	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	0.13631104457448973	[75]	[462]	1	hSpCas9	negative selection	12260488
20172782	20172805	X	+	28162770	OCIAML2	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	0.229809892898931	[29]	[194]	2	hSpCas9	negative selection	12260489
20156197	20156220	X	+	28162770	OCIAML2	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.49919897743893227	[101]	[399]	-4	hSpCas9	negative selection	12260490
20266587	20266610	X	-	28162770	OCIAML2	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	1.5293701747578385	[3]	[63]	9	hSpCas9	negative selection	12260491
20204011	20204034	X	+	28162770	OCIAML2	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	0.16810393191997552	[78]	[491]	1	hSpCas9	negative selection	12260492
20266611	20266634	X	-	28162770	OCIAML3	viability	GATGCCGCTGGCGCAGCTGGCGG	RPS6KA3	ENSG00000177189	1.097870064313505	[12]	[83]	8	hSpCas9	negative selection	12429849
20195098	20195121	X	-	28162770	OCIAML3	viability	GGAACGTGATATCTTGGTAGAGG	RPS6KA3	ENSG00000177189	-0.734706503233905	[112]	[204]	-5	hSpCas9	negative selection	12429850
20234775	20234798	X	-	28162770	OCIAML3	viability	GGATGAACCTATGGGAGAGGAGG	RPS6KA3	ENSG00000177189	-0.2808497550645329	[32]	[81]	-2	hSpCas9	negative selection	12429851
20161675	20161698	X	-	28162770	OCIAML3	viability	GGAAAATTCTCACTCAGTGGTGG	RPS6KA3	ENSG00000177189	-1.2675068156469766	[62]	[78]	-7	hSpCas9	negative selection	12429852
20156108	20156131	X	-	28162770	OCIAML3	viability	GGATGCACCACATCTAGTAAAGG	RPS6KA3	ENSG00000177189	-0.3224112209869452	[139]	[337]	-3	hSpCas9	negative selection	12429853
20266563	20266586	X	-	28162770	OCIAML3	viability	GAGCCCGTCCGACAGCGCTGAGG	RPS6KA3	ENSG00000177189	-0.43301576365185834	[71]	[160]	-3	hSpCas9	negative selection	12429854
20172782	20172805	X	+	28162770	OCIAML3	viability	ACATCTCTTGCAAACAGAGTAGG	RPS6KA3	ENSG00000177189	-0.5505060016875767	[48]	[100]	-4	hSpCas9	negative selection	12429855
20156197	20156220	X	+	28162770	OCIAML3	viability	GCAGCAGTCAGTCTCTGATGAGG	RPS6KA3	ENSG00000177189	-0.349504517381967	[110]	[262]	-3	hSpCas9	negative selection	12429856
20266587	20266610	X	-	28162770	OCIAML3	viability	CCCGTGGCAGAAGATGGCTGTGG	RPS6KA3	ENSG00000177189	-2.786652718266559	[15]	[6]	-9	hSpCas9	negative selection	12429857
20204011	20204034	X	+	28162770	OCIAML3	viability	GCAACACTTACCTTTCAGTGTGG	RPS6KA3	ENSG00000177189	-0.38378993293381747	[101]	[235]	-3	hSpCas9	negative selection	12429858