Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6199
  • Symbol: RPS6KB2
  • Description: ribosomal protein S6 kinase B2
DataSource: http://genomecrispr.dkfz.de/#!/results/RPS6KB2

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
67429123 67429146 11 + 26472758 Jiyoye viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.13135154622499834 [320] [220] -1 hSpCas9 negative selection 140292
67428991 67429014 11 - 26472758 Jiyoye viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 5.53645839845084 [0] [34] 9 hSpCas9 negative selection 140293
67428573 67428596 11 + 26472758 Jiyoye viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 3.164605078231795 [20] [141] 9 hSpCas9 negative selection 140294
67428560 67428583 11 + 26472758 Jiyoye viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 2.7048559301465582 [11] [58] 9 hSpCas9 negative selection 140295
67428602 67428625 11 + 26472758 Jiyoye viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 3.3331748000620967 [4] [37] 9 hSpCas9 negative selection 140296
67429123 67429146 11 + 26472758 KBM7 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.4766656634885169 [1060,826] [297,332] -4 hSpCas9 negative selection 331410
67428991 67429014 11 - 26472758 KBM7 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.041995907140281674 [362,307] [186,121] 0 hSpCas9 negative selection 331411
67428573 67428596 11 + 26472758 KBM7 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.544523034331602 [662,718] [266,186] -5 hSpCas9 negative selection 331412
67428560 67428583 11 + 26472758 KBM7 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 1.5544767729600393 [265,165] [439,160] 9 hSpCas9 negative selection 331413
67428602 67428625 11 + 26472758 KBM7 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.10361906132469523 [220,176] [104,69] -1 hSpCas9 negative selection 331414
67429123 67429146 11 + 26472758 Raji viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.3000286133159953 [398] [113] 3 hSpCas9 negative selection 522528
67428991 67429014 11 - 26472758 Raji viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 1.0791866435429474 [154] [75] 8 hSpCas9 negative selection 522529
67428573 67428596 11 + 26472758 Raji viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.46677221039097383 [398] [66] -4 hSpCas9 negative selection 522530
67428560 67428583 11 + 26472758 Raji viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.3265008246771864 [188] [54] 3 hSpCas9 negative selection 522531
67428602 67428625 11 + 26472758 Raji viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -1.246253419241101 [91] [8] -7 hSpCas9 negative selection 522532
67429123 67429146 11 + 26472758 K562 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.7365229365178685 [751] [380] -4 hSpCas9 negative selection 713646
67428991 67429014 11 - 26472758 K562 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.9735648173733538 [221] [367] 7 hSpCas9 negative selection 713647
67428573 67428596 11 + 26472758 K562 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.9896083941534044 [580] [246] -5 hSpCas9 negative selection 713648
67428560 67428583 11 + 26472758 K562 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.03420102027610117 [176] [152] 0 hSpCas9 negative selection 713649
67428602 67428625 11 + 26472758 K562 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -1.3856316625832474 [129] [41] -6 hSpCas9 negative selection 713650
67428544 67428567 11 - 26627737 DLD1 viability CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.7519295426689114 [366] [46,93,64] -6 hSpCas9 negative selection 780540
67428991 67429014 11 - 26627737 DLD1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.26016504050015776 [355] [124,163,114] 2 hSpCas9 negative selection 780541
67429574 67429597 11 + 26627737 DLD1 viability TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.36849443565052953 [330] [71,147,174] 4 hSpCas9 negative selection 780542
67428544 67428567 11 - 26627737 GBM cells viability after 5 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.0830145521922962 [237] [102,137] -1 hSpCas9 negative selection 862855
67428991 67429014 11 - 26627737 GBM cells viability after 5 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.4370821641279005 [187] [123,148] 6 hSpCas9 negative selection 862856
67429574 67429597 11 + 26627737 GBM cells viability after 5 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.3204470854573007 [276] [152,217] 5 hSpCas9 negative selection 862857
67428544 67428567 11 - 26627737 GBM cells viability after 13 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.20574175522292587 [237] [138,156] 2 hSpCas9 negative selection 945170
67428991 67429014 11 - 26627737 GBM cells viability after 13 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.17871214041966182 [187] [131,101] 2 hSpCas9 negative selection 945171
67429574 67429597 11 + 26627737 GBM cells viability after 13 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.17843813378064474 [276] [195,148] 2 hSpCas9 negative selection 945172
67428544 67428567 11 - 26627737 GBM cells viability after 21 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.34365158369854315 [237] [173,154] 3 hSpCas9 negative selection 1027485
67428991 67429014 11 - 26627737 GBM cells viability after 21 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.43591023871261525 [187] [145,130] 4 hSpCas9 negative selection 1027486
67429574 67429597 11 + 26627737 GBM cells viability after 21 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.13553101957561783 [276] [157,171] 1 hSpCas9 negative selection 1027487
67428544 67428567 11 - 26627737 RPE1 viability after 9 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.20707566816537526 [640] [189,152] -1 hSpCas9 negative selection 1109800
67428991 67429014 11 - 26627737 RPE1 viability after 9 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.14375210961518514 [694] [180,316] 1 hSpCas9 negative selection 1109801
67429574 67429597 11 + 26627737 RPE1 viability after 9 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.6868906480330933 [1669] [336,308] -5 hSpCas9 negative selection 1109802
67428544 67428567 11 - 26627737 RPE1 viability after 12 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.1186048810511793 [640] [236,133] 0 hSpCas9 negative selection 1192115
67428991 67429014 11 - 26627737 RPE1 viability after 12 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.15825590586718666 [694] [203,212] 1 hSpCas9 negative selection 1192116
67429574 67429597 11 + 26627737 RPE1 viability after 12 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.10640840770014393 [1669] [425,406] 0 hSpCas9 negative selection 1192117
67428544 67428567 11 - 26627737 RPE1 viability after 15 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.5241230639294784 [640] [386,138] 3 hSpCas9 negative selection 1274430
67428991 67429014 11 - 26627737 RPE1 viability after 15 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.18919602689318224 [694] [271,177] 1 hSpCas9 negative selection 1274431
67429574 67429597 11 + 26627737 RPE1 viability after 15 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.1668662465733436 [1669] [515,328] -1 hSpCas9 negative selection 1274432
67428544 67428567 11 - 26627737 RPE1 viability after 18 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.3880477089383852 [640] [195,63] -2 hSpCas9 negative selection 1356745
67428991 67429014 11 - 26627737 RPE1 viability after 18 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.02619212208537966 [694] [219,159] 0 hSpCas9 negative selection 1356746
67429574 67429597 11 + 26627737 RPE1 viability after 18 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.9173018526694334 [1669] [227,249] -5 hSpCas9 negative selection 1356747
67428544 67428567 11 - 26627737 HeLa viability after 8 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.3646502271023836 [153] [176,47,55] 3 hSpCas9 negative selection 1439060
67428991 67429014 11 - 26627737 HeLa viability after 8 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 1.5009384521214222 [301] [233,576,280] 9 hSpCas9 negative selection 1439061
67429574 67429597 11 + 26627737 HeLa viability after 8 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.6702653250718018 [492] [210,131,81] -6 hSpCas9 negative selection 1439062
67428544 67428567 11 - 26627737 HeLa viability after 12 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.3482111935395042 [153] [248,82,164] 8 hSpCas9 negative selection 1521375
67428991 67429014 11 - 26627737 HeLa viability after 12 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.933278072809858 [301] [173,314,215] 7 hSpCas9 negative selection 1521376
67429574 67429597 11 + 26627737 HeLa viability after 12 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.6342529954605891 [492] [233,81,85] -5 hSpCas9 negative selection 1521377
67428544 67428567 11 - 26627737 HeLa viability after 15 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.6666569364925827 [153] [155,129,320] 9 hSpCas9 negative selection 1603690
67428991 67429014 11 - 26627737 HeLa viability after 15 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.42338005182761723 [301] [86,178,234] 3 hSpCas9 negative selection 1603691
67429574 67429597 11 + 26627737 HeLa viability after 15 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -1.4648112038023897 [492] [91,87,34] -8 hSpCas9 negative selection 1603692
67428544 67428567 11 - 26627737 HeLa viability after 18 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.6652192813082856 [153] [99,112,320] 9 hSpCas9 negative selection 1686005
67428991 67429014 11 - 26627737 HeLa viability after 18 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.42810713769862846 [301] [53,154,234] 3 hSpCas9 negative selection 1686006
67429574 67429597 11 + 26627737 HeLa viability after 18 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -1.446788032557294 [492] [60,75,34] -8 hSpCas9 negative selection 1686007
67428544 67428567 11 - 26627737 HCT116 viability after 6 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 2.6862789239110176 [263] [270,264] 9 hSpCas9 negative selection 1768320
67428991 67429014 11 - 26627737 HCT116 viability after 6 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.3932577897716179 [849] [171,62] -2 hSpCas9 negative selection 1768321
67429574 67429597 11 + 26627737 HCT116 viability after 6 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.5764635473381945 [566] [81,160] 3 hSpCas9 negative selection 1768322
67428544 67428567 11 - 26627737 HCT116 viability after 8 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.1629119951687448 [126] [131,210,126] 8 hSpCas9 negative selection 1850635
67428991 67429014 11 - 26627737 HCT116 viability after 8 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.635076909725139 [271] [215,166,313] 6 hSpCas9 negative selection 1850636
67429574 67429597 11 + 26627737 HCT116 viability after 8 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.5835628869072114 [382] [106,182,131] -6 hSpCas9 negative selection 1850637
67428544 67428567 11 - 26627737 HCT116 viability after 9 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.7643961330173419 [263] [520,16] 9 hSpCas9 negative selection 1932950
67428991 67429014 11 - 26627737 HCT116 viability after 9 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.09280253089099122 [849] [274,215] 0 hSpCas9 negative selection 1932951
67429574 67429597 11 + 26627737 HCT116 viability after 9 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.48870629962674267 [566] [398,64] 3 hSpCas9 negative selection 1932952
67428544 67428567 11 - 26627737 HCT116 viability after 12 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.94559222839488 [126] [173,60,144] 7 hSpCas9 negative selection 2015265
67428991 67429014 11 - 26627737 HCT116 viability after 12 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.9943552737074466 [271] [328,225,293] 8 hSpCas9 negative selection 2015266
67429574 67429597 11 + 26627737 HCT116 viability after 12 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.7499602923470545 [382] [76,127,157] -7 hSpCas9 negative selection 2015267
67428544 67428567 11 - 26627737 HCT116 viability after 15 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.244807984066818 [126] [165,119,230] 8 hSpCas9 negative selection 2097580
67428991 67429014 11 - 26627737 HCT116 viability after 15 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.6921099182413953 [271] [361,282,126] 6 hSpCas9 negative selection 2097581
67429574 67429597 11 + 26627737 HCT116 viability after 15 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.7217984639171633 [382] [139,134,125] -6 hSpCas9 negative selection 2097582
67428544 67428567 11 - 26627737 HCT116 viability after 18 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 1.1611167049792992 [126] [79,142,190] 8 hSpCas9 negative selection 2179895
67428991 67429014 11 - 26627737 HCT116 viability after 18 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.6133352761414841 [271] [195,198,208] 5 hSpCas9 negative selection 2179896
67429574 67429597 11 + 26627737 HCT116 viability after 18 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.4860652193871223 [382] [20,182,191] -4 hSpCas9 negative selection 2179897
67428544 67428567 11 - 24336569 HL60 viability CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 0.2765961437583343 [622] [1596] 2 hSpCas9 negative selection 2293028
67428551 67428574 11 + 24336569 HL60 viability GGCCGTGTTTGATTTGGATTTGG RPS6KB2 ENSG00000175634 0.4784743764097833 [251] [742] 4 hSpCas9 negative selection 2293029
67428557 67428580 11 + 24336569 HL60 viability GTTTGATTTGGATTTGGAGACGG RPS6KB2 ENSG00000175634 0.3666021990374181 [474] [1295] 3 hSpCas9 negative selection 2293030
67428564 67428587 11 + 24336569 HL60 viability TTGGATTTGGAGACGGAGGAAGG RPS6KB2 ENSG00000175634 0.2743787519815769 [823] [2108] 2 hSpCas9 negative selection 2293031
67428572 67428595 11 + 24336569 HL60 viability GGAGACGGAGGAAGGCAGCGAGG RPS6KB2 ENSG00000175634 -1.0547841941140517 [1767] [1800] -7 hSpCas9 negative selection 2293032
67428578 67428601 11 + 24336569 HL60 viability GGAGGAAGGCAGCGAGGGCGAGG RPS6KB2 ENSG00000175634 0.7204175796685411 [414] [1446] 6 hSpCas9 negative selection 2293033
67428992 67429015 11 - 24336569 HL60 viability AGCTGCCCTCAACTCGGCAAGGG RPS6KB2 ENSG00000175634 1.3263570598507124 [237] [1262] 8 hSpCas9 negative selection 2293034
67428998 67429021 11 - 24336569 HL60 viability TAGGCCAGCTGCCCTCAACTCGG RPS6KB2 ENSG00000175634 0.4864856682565948 [1506] [4467] 4 hSpCas9 negative selection 2293035
67429106 67429129 11 + 24336569 HL60 viability CCTTGTGTCCGTAGGCCTGTGGG RPS6KB2 ENSG00000175634 -0.30321632002855115 [750] [1287] -3 hSpCas9 negative selection 2293036
67429120 67429143 11 + 24336569 HL60 viability GCCTGTGGGACACTATGAAGAGG RPS6KB2 ENSG00000175634 -0.4734074290088566 [722] [1101] -4 hSpCas9 negative selection 2293037
67428544 67428567 11 - 24336569 KBM7 viability CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.13018294917957318 [828] [2065] -1 hSpCas9 negative selection 2360205
67428551 67428574 11 + 24336569 KBM7 viability GGCCGTGTTTGATTTGGATTTGG RPS6KB2 ENSG00000175634 -0.4795220890516372 [136] [267] -4 hSpCas9 negative selection 2360206
67428557 67428580 11 + 24336569 KBM7 viability GTTTGATTTGGATTTGGAGACGG RPS6KB2 ENSG00000175634 0.09260461995991318 [468] [1363] 0 hSpCas9 negative selection 2360207
67428564 67428587 11 + 24336569 KBM7 viability TTGGATTTGGAGACGGAGGAAGG RPS6KB2 ENSG00000175634 0.5350360398376088 [813] [3216] 5 hSpCas9 negative selection 2360208
67428572 67428595 11 + 24336569 KBM7 viability GGAGACGGAGGAAGGCAGCGAGG RPS6KB2 ENSG00000175634 -3.312997094737266 [1482] [406] -9 hSpCas9 negative selection 2360209
67428578 67428601 11 + 24336569 KBM7 viability GGAGGAAGGCAGCGAGGGCGAGG RPS6KB2 ENSG00000175634 -1.2458620364940858 [752] [865] -7 hSpCas9 negative selection 2360210
67428992 67429015 11 - 24336569 KBM7 viability AGCTGCCCTCAACTCGGCAAGGG RPS6KB2 ENSG00000175634 -0.06038968222315533 [254] [666] 0 hSpCas9 negative selection 2360211
67428998 67429021 11 - 24336569 KBM7 viability TAGGCCAGCTGCCCTCAACTCGG RPS6KB2 ENSG00000175634 0.36021824737944375 [1396] [4890] 3 hSpCas9 negative selection 2360212
67429106 67429129 11 + 24336569 KBM7 viability CCTTGTGTCCGTAGGCCTGTGGG RPS6KB2 ENSG00000175634 1.4143092744772272 [444] [3234] 9 hSpCas9 negative selection 2360213
67429120 67429143 11 + 24336569 KBM7 viability GCCTGTGGGACACTATGAAGAGG RPS6KB2 ENSG00000175634 -0.5546929410341918 [558] [1037] -4 hSpCas9 negative selection 2360214
67428603 67428626 11 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.5998487828251656 [3,3] [1,1] -7 hSpCas9 positive selection 3017996
67428553 67428576 11 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 -0.1466862008509976 [3,2] [2,2] -2 hSpCas9 positive selection 3017997
67428603 67428626 11 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.4828308947628258 [3,3] [2,0] -7 hSpCas9 positive selection 3085854
67428553 67428576 11 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 0.21340277314956746 [3,3] [3,2] 4 hSpCas9 positive selection 3085855
67429198 67429221 + 24336571 A375 resistance to PLX after 7 days CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 0.32642807569415444 [18,19] [21,26] 8 hSpCas9 positive selection 3141912
67429198 67429221 + 24336571 A375 resistance to PLX after 14 days CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 0.4928026436606918 [17,24] [15,11] 4 hSpCas9 positive selection 3199705
67429198 67429221 + 24336571 A375 viability after 7 days CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 0.6353613231570894 [12] [18,19] 8 hSpCas9 negative selection 3257498
67429198 67429221 + 24336571 A375 viability after 14 days CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 0.7848436839701575 [12] [17,24] 8 hSpCas9 negative selection 3315291
67429158 67429181 11 - 27383988 293T resistance to West Nile virus (flavivirus) CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 1.7337642553888224 [45,45] [0,0] 7 hSpCas9 positive selection 3390685
67428986 67429009 11 + 27383988 293T resistance to West Nile virus (flavivirus) CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.9025451253325543 [285,285] [0,0] -6 hSpCas9 positive selection 3390686
67428602 67428625 11 + 26780180 HT29 viability (Avana library 4 designs) CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 2.13108702869093 [] [] 7 hSpCas9 negative selection 3456377
67428553 67428576 11 - 26780180 HT29 viability (Avana library 4 designs) CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 -0.587692870201661 [] [] -8 hSpCas9 negative selection 3456378
67428602 67428625 11 + 26780180 A375 viability (Avana lentiCRISPRv2) CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 3.10137776217584 [] [] 5 hSpCas9 negative selection 3554826
67428553 67428576 11 - 26780180 A375 viability (Avana lentiCRISPRv2) CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 -6.01641575820211 [] [] -6 hSpCas9 negative selection 3554827
67428991 67429014 11 - 26780180 A375 viability (Avana lentiCRISPRv2) GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 4.91387853608527 [] [] 8 hSpCas9 negative selection 3554828
67428602 67428625 11 + 26780180 A375 viability (Avana lentiGuide) CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 7.86840787023558 [] [] 6 hSpCas9 negative selection 3663485
67428553 67428576 11 - 26780180 A375 viability (Avana lentiGuide) CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 -3.17727388367404 [] [] -5 hSpCas9 negative selection 3663486
67428991 67429014 11 - 26780180 A375 viability (Avana lentiGuide) GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 5.58280371592592 [] [] 5 hSpCas9 negative selection 3663487
67428602 67428625 11 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.21584902782507218 [4] [4,2] -3 hSpCas9 positive selection 3772092
67428553 67428576 11 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 -1.1675065856604157 [4] [1,1] -9 hSpCas9 positive selection 3772093
67428991 67429014 11 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.41832269459284654 [4] [6,6] 9 hSpCas9 positive selection 3772094
67428602 67428625 11 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.1825710667612762 [5] [4,2] -3 hSpCas9 positive selection 3880699
67428553 67428576 11 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTCCAAATCCAAATCAAACACGG RPS6KB2 ENSG00000175634 0.29542720140477374 [4] [4,4] 8 hSpCas9 positive selection 3880700
67428991 67429014 11 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.11359183227572203 [5] [4,3] -1 hSpCas9 positive selection 3880701
67428986 67429009 11 + 26780180 A375 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.833924222281272 [] [] 3 hSpCas9 negative selection 3990725
67429158 67429181 11 - 26780180 A375 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 1.00625233641625 [] [] 4 hSpCas9 negative selection 3990726
67428986 67429009 11 + 26780180 HT29 viability (GeCKOv2 library) CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.41247644642754 [] [] 1 hSpCas9 negative selection 4098691
67429158 67429181 11 - 26780180 HT29 viability (GeCKOv2 library) CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 1.42132506104721 [] [] 7 hSpCas9 negative selection 4098692
67429198 67429221 11 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 0.19093156223971047 [3] [2,3] 5 hSpCas9 positive selection 4167601
67429198 67429221 11 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CTTTGAGCTGCTGCGTGTGCTGG RPS6KB2 ENSG00000175634 1.1735437476843946 [4] [2,4,2,4] 8 hSpCas9 positive selection 4231623
67429158 67429181 11 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.5470767833147797 [1] [0,0] -8 hSpCas9 positive selection 4360063
67428986 67429009 11 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.06643468295507565 [3] [3,2] 1 hSpCas9 positive selection 4360065
67429167 67429189 11 + 27760321 OCIAML3 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.11627544773168774 [830,697] [522,583] -1 hSpCas9 negative selection 4435978
67429167 67429189 11 + 27760321 OCIAML2 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.22941395669552023 [830,697] [411,674] -3 hSpCas9 negative selection 4519441
67429167 67429189 11 + 27760321 MV411 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 0.4832328232647617 [830,697] [821,522] 3 hSpCas9 negative selection 4602904
67429167 67429189 11 + 27760321 HL60 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.33773958916173275 [830,697] [483,500] -4 hSpCas9 negative selection 4686367
67429167 67429189 11 + 27760321 HT1080 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.2979323716268451 [697,544] [135,272] -1 hSpCas9 negative selection 4769830
67429167 67429189 11 + 27760321 HT29 viability after 7 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.10762773663424496 [697,544] [896,733,618] -1 hSpCas9 negative selection 4853293
67429167 67429189 11 + 27760321 HT29 viability after 25 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.01690420720931407 [697,544] [880,688,502] 0 hSpCas9 negative selection 4936756
67429167 67429189 11 + 27760321 HT29 viability after 22 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 0.1388750525378324 [697,544] [703,842,828] 1 hSpCas9 negative selection 5020219
67429167 67429189 11 + 27760321 HT29 viability after 19 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.1325178969501969 [697,544] [553,652,724] -1 hSpCas9 negative selection 5103682
67429167 67429189 11 + 27760321 HT29 viability after 16 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.2527368164899769 [697,544] [727,406,633] -3 hSpCas9 negative selection 5187145
67429167 67429189 11 + 27760321 HT29 viability after 13 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 -0.27532592725639704 [697,544] [530,535,712] -3 hSpCas9 negative selection 5270608
67429167 67429189 11 + 27760321 HT29 viability after 10 days ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 0.47499025989990873 [697,544] [832,1177,1223] 6 hSpCas9 negative selection 5354071
67429167 67429189 11 + 27760321 MOLM13 viability ACGTTGGCCCAGAGCGCATCGG RPS6KB2 ENSG00000175634 0.6241056213362172 [830,697] [860,492] 4 hSpCas9 negative selection 5437534
67428495 67428518 11 + 27661255 K562 viability GTCAGTGCGCGGCCAGGTACGGG RPS6KB2 ENSG00000175634 0.14037063121768908 [651,796] [654,618] 5 dCas9-KRAB negative selection 5508647
67428964 67428987 11 - 27661255 K562 viability GCGTCCTGTGAGAAACCGAGGGG RPS6KB2 ENSG00000175634 -0.14428768370930922 [212,242] [158,168] -5 dCas9-KRAB negative selection 5508648
67429158 67429181 11 - 27260156 BXPC3 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.7275678653914375 [140] [43,69,67,191] -9 hSpCas9 negative selection 5632523
67428986 67429009 11 + 27260156 BXPC3 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.03211423425227877 [725] [551,768,963,851] 0 hSpCas9 negative selection 5632525
67429158 67429181 11 - 27260156 A673 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.7583613230273578 [140] [108,114,105,68] -9 hSpCas9 negative selection 5753774
67428986 67429009 11 + 27260156 A673 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.13103820729829052 [725] [1017,834,980,994] 3 hSpCas9 negative selection 5753776
67429158 67429181 11 - 27260156 A375 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.29033709101531024 [140] [133,155,133,118] -4 hSpCas9 negative selection 5875025
67428986 67429009 11 + 27260156 A375 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.14370340980793145 [725] [637,950,468,1004] -2 hSpCas9 negative selection 5875027
67429158 67429181 11 - 27260156 COLO741 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.3984133605383693 [140] [48,109,45] -9 hSpCas9 negative selection 5996276
67428986 67429009 11 + 27260156 COLO741 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.016303009392860335 [725] [1040,954,832] 0 hSpCas9 negative selection 5996278
67429158 67429181 11 - 27260156 CAL120 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.3012975976165573 [140] [59,87,63] -9 hSpCas9 negative selection 6117527
67428986 67429009 11 + 27260156 CAL120 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.16253400612391677 [725] [919,1068,1029] 2 hSpCas9 negative selection 6117529
67429158 67429181 11 - 27260156 CADOES1 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.35294989621279327 [140] [65,108,51,186] -6 hSpCas9 negative selection 6238778
67428986 67429009 11 + 27260156 CADOES1 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.12938635108947472 [725] [739,714,817,678] 2 hSpCas9 negative selection 6238780
67429158 67429181 11 - 27260156 EWS502 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.2538818545501302 [140] [53,24,87,87] -9 hSpCas9 negative selection 6360029
67428986 67429009 11 + 27260156 EWS502 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.21776812285685598 [725] [616,1031,881,1083] 4 hSpCas9 negative selection 6360031
67429158 67429181 11 - 27260156 EW8 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.5988235555571053 [140] [154,35,52,69] -8 hSpCas9 negative selection 6481280
67428986 67429009 11 + 27260156 EW8 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.1579660157549987 [725] [796,639,473,758] 3 hSpCas9 negative selection 6481282
67429158 67429181 11 - 27260156 CORL105 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.4871443817335324 [140] [26,85,90,34] -9 hSpCas9 negative selection 6602531
67428986 67429009 11 + 27260156 CORL105 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.04405863967185586 [725] [804,727,1043,755] -1 hSpCas9 negative selection 6602533
67429158 67429181 11 - 27260156 HS294T viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.3854971373264513 [140] [17,16,26,21] -9 hSpCas9 negative selection 6723782
67428986 67429009 11 + 27260156 HS294T viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.19841221414613364 [725] [292,252,336,426] 2 hSpCas9 negative selection 6723784
67429158 67429181 11 - 27260156 HCC44 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.0259869061012326 [140] [83,49,136,56] -8 hSpCas9 negative selection 6845033
67428986 67429009 11 + 27260156 HCC44 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.024728217333421676 [725] [809,526,1207,786] 0 hSpCas9 negative selection 6845035
67429158 67429181 11 - 27260156 G402 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.8356253432665468 [140] [176,143,31,48] -7 hSpCas9 negative selection 6966284
67428986 67429009 11 + 27260156 G402 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.05447124228056688 [725] [927,962,637,1139] 0 hSpCas9 negative selection 6966286
67429158 67429181 11 - 27260156 L33 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.1076939595279585 [140] [70,31,46,37] -9 hSpCas9 negative selection 7087535
67428986 67429009 11 + 27260156 L33 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.22353956528607066 [725] [973,348,495,772] 5 hSpCas9 negative selection 7087537
67429158 67429181 11 - 27260156 K562 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.8629240068116026 [140] [31,60,123,55] -7 hSpCas9 negative selection 7208786
67428986 67429009 11 + 27260156 K562 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.4687081527174961 [725] [982,1333,834,488] 6 hSpCas9 negative selection 7208788
67429158 67429181 11 - 27260156 HT29 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.9330004066045332 [140] [48,103,108,93] -8 hSpCas9 negative selection 7330037
67428986 67429009 11 + 27260156 HT29 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.19981453644318836 [725] [914,1013,1001,1097] 4 hSpCas9 negative selection 7330039
67429158 67429181 11 - 27260156 MHHES1 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.6341330926101814 [140] [99,152,63,95] -8 hSpCas9 negative selection 7451288
67428986 67429009 11 + 27260156 MHHES1 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.11572524184634492 [725] [748,665,585,943] -2 hSpCas9 negative selection 7451290
67429158 67429181 11 - 27260156 MEWO viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.4293365858014655 [140] [169,59,77] -7 hSpCas9 negative selection 7572539
67428986 67429009 11 + 27260156 MEWO viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.20432677948601563 [725] [876,741,746] 4 hSpCas9 negative selection 7572541
67429158 67429181 11 - 27260156 LNCAPCLONEFGC viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 0.5309484057315954 [140] [41,98,625,44] 8 hSpCas9 negative selection 7693790
67428986 67429009 11 + 27260156 LNCAPCLONEFGC viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.09565068009277922 [725] [652,556,705,561] -1 hSpCas9 negative selection 7693792
67429158 67429181 11 - 27260156 PANC0327 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 0.05840800521533729 [140] [148,224,103,32] 0 hSpCas9 negative selection 7815041
67428986 67429009 11 + 27260156 PANC0327 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.17461040370796982 [725] [601,413,511,779] -3 hSpCas9 negative selection 7815043
67429158 67429181 11 - 27260156 NCIH2009 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.5457954776620728 [140] [105,183,107] -6 hSpCas9 negative selection 7936292
67428986 67429009 11 + 27260156 NCIH2009 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.23146814105947577 [725] [1423,1170,1021] 3 hSpCas9 negative selection 7936294
67429158 67429181 11 - 27260156 NCIH1373 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.3343569823802637 [140] [88,53,245,28] -3 hSpCas9 negative selection 8057543
67428986 67429009 11 + 27260156 NCIH1373 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.3310439926664635 [725] [723,711,452,185] -3 hSpCas9 negative selection 8057545
67429158 67429181 11 - 27260156 PATU8902 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.3473171059269997 [140] [166,47,5,107] -8 hSpCas9 negative selection 8178794
67428986 67429009 11 + 27260156 PATU8902 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.8597930587402842 [725] [627,453,585,545] -7 hSpCas9 negative selection 8178796
67429158 67429181 11 - 27260156 PANC1 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.3443490403248 [140] [19,45,66,55] -9 hSpCas9 negative selection 8300045
67428986 67429009 11 + 27260156 PANC1 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.4078337441444648 [725] [694,921,860,837] 6 hSpCas9 negative selection 8300047
67429158 67429181 11 - 27260156 PANC0813 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.6369030675325325 [140] [102,168,42,109] -7 hSpCas9 negative selection 8421296
67428986 67429009 11 + 27260156 PANC0813 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.14703762666885478 [725] [1136,788,761,1095] 2 hSpCas9 negative selection 8421298
67429158 67429181 11 - 27260156 RDES viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.0830524435113296 [140] [61,47,115,86] -9 hSpCas9 negative selection 8542547
67428986 67429009 11 + 27260156 RDES viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.3375436800674038 [725] [572,573,781,736] -5 hSpCas9 negative selection 8542549
67429158 67429181 11 - 27260156 PC3 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.7106718763338942 [140] [54,118,131,56] -9 hSpCas9 negative selection 8663798
67428986 67429009 11 + 27260156 PC3 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.019371081401553192 [725] [518,709,976,759] 0 hSpCas9 negative selection 8663800
67429158 67429181 11 - 27260156 PATU8988T viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.40941464227011815 [140] [142,80,77,106] -6 hSpCas9 negative selection 8785049
67428986 67429009 11 + 27260156 PATU8988T viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.008402056524345336 [725] [774,675,644,691] 0 hSpCas9 negative selection 8785051
67429158 67429181 11 - 27260156 T47D viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.7010144022179217 [140] [120,75,93,115] -8 hSpCas9 negative selection 8906300
67428986 67429009 11 + 27260156 T47D viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.015669203186025493 [725] [901,645,914,900] 0 hSpCas9 negative selection 8906302
67429158 67429181 11 - 27260156 SU8686 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -2.073216486010577 [140] [38,11,39,45] -9 hSpCas9 negative selection 9027551
67428986 67429009 11 + 27260156 SU8686 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.11254328545774861 [725] [745,690,938,744] 2 hSpCas9 negative selection 9027553
67429158 67429181 11 - 27260156 SKES1 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.6462586973383904 [140] [83,160,62,61] -8 hSpCas9 negative selection 9148802
67428986 67429009 11 + 27260156 SKES1 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.14665426436489504 [725] [1137,774,599,738] 3 hSpCas9 negative selection 9148804
67429158 67429181 11 - 27260156 TOV112D viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -1.129853138727438 [140] [58,102,75,29] -9 hSpCas9 negative selection 9270053
67428986 67429009 11 + 27260156 TOV112D viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.028918148239768682 [725] [737,643,818,635] 0 hSpCas9 negative selection 9270055
67429158 67429181 11 - 27260156 TC71 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.9980316985903277 [140] [18,69,76,141] -9 hSpCas9 negative selection 9391304
67428986 67429009 11 + 27260156 TC71 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 0.09255664355493443 [725] [846,880,781,808] 2 hSpCas9 negative selection 9391306
67429158 67429181 11 - 27260156 TC32 viability CTCTGGGCCAACGTTCACGCTGG RPS6KB2 ENSG00000175634 -0.7615448486485497 [140] [90,30,98,108] -9 hSpCas9 negative selection 9512555
67428986 67429009 11 + 27260156 TC32 viability CATGTCCCCTTGCCGAGTTGAGG RPS6KB2 ENSG00000175634 -0.05809667268540375 [725] [552,445,1029,715] -1 hSpCas9 negative selection 9512557
67428544 67428567 11 - 27869803 HPAFII viability after 27 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.4404069030642272 [297] [175,64,NaN] -3 hSpCas9 negative selection 9543540
67428991 67429014 11 - 27869803 HPAFII viability after 27 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.1254573227244452 [268] [204,111,NaN] 1 hSpCas9 negative selection 9543541
67429574 67429597 11 + 27869803 HPAFII viability after 27 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.22155131971528605 [287] [25,301,NaN] 1 hSpCas9 negative selection 9543542
67428544 67428567 11 - 27869803 HPAFII viability after 15 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.5008788347194304 [297] [332,159,NaN] -5 hSpCas9 negative selection 9625989
67428991 67429014 11 - 27869803 HPAFII viability after 15 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.16866317665183211 [268] [385,286,NaN] 2 hSpCas9 negative selection 9625990
67429574 67429597 11 + 27869803 HPAFII viability after 15 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.133335946355789 [287] [259,295,NaN] -1 hSpCas9 negative selection 9625991
67428544 67428567 11 - 27869803 ASPC1 viability after 36 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.6638388255508554 [541] [68,41,214] -6 hSpCas9 negative selection 9708438
67428991 67429014 11 - 27869803 ASPC1 viability after 36 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.1323786436207514 [662] [81,417,240] 1 hSpCas9 negative selection 9708439
67429574 67429597 11 + 27869803 ASPC1 viability after 36 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.17938757557400203 [678] [304,270,90] -2 hSpCas9 negative selection 9708440
67428544 67428567 11 - 27869803 PATU8988S viability after 35 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.354545054477554 [626] [198,195,NaN] -4 hSpCas9 negative selection 9790887
67428991 67429014 11 - 27869803 PATU8988S viability after 35 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.547720551142048 [598] [417,286,NaN] 6 hSpCas9 negative selection 9790888
67429574 67429597 11 + 27869803 PATU8988S viability after 35 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.023217771625731756 [587] [248,216,NaN] 0 hSpCas9 negative selection 9790889
67428544 67428567 11 - 27869803 PATU8988S viability after 31 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -0.2026759561275868 [626] [240,186,NaN] -2 hSpCas9 negative selection 9873336
67428991 67429014 11 - 27869803 PATU8988S viability after 31 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.24611129707866775 [598] [255,317,NaN] 3 hSpCas9 negative selection 9873337
67429574 67429597 11 + 27869803 PATU8988S viability after 31 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 -0.2426264001785949 [587] [235,149,NaN] -3 hSpCas9 negative selection 9873338
67428544 67428567 11 - 27869803 HPAFII viability after 35 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -1.210419849925687 [297] [99,25,NaN] -6 hSpCas9 negative selection 9955785
67428991 67429014 11 - 27869803 HPAFII viability after 35 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.6278826642439446 [268] [264,148,NaN] 4 hSpCas9 negative selection 9955786
67429574 67429597 11 + 27869803 HPAFII viability after 35 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.6688904675157721 [287] [61,422,NaN] 4 hSpCas9 negative selection 9955787
67428544 67428567 11 - 27869803 HPAFII viability after 31 days CAAATCAAACACGGCCGCCATGG RPS6KB2 ENSG00000175634 -1.6563222377964495 [297] [98,2,NaN] -7 hSpCas9 negative selection 10038234
67428991 67429014 11 - 27869803 HPAFII viability after 31 days GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.20591797012591107 [268] [176,170,NaN] 1 hSpCas9 negative selection 10038235
67429574 67429597 11 + 27869803 HPAFII viability after 31 days TGCCATGAAAGTCCTAAGGAAGG RPS6KB2 ENSG00000175634 0.6503040461584071 [287] [78,443,NaN] 5 hSpCas9 negative selection 10038236
67429123 67429146 11 + 28162770 P31FUJ viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.6467919456796298 [280] [516] 7 hSpCas9 negative selection 10228139
67428991 67429014 11 - 28162770 P31FUJ viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.49266933116948947 [181] [151] -4 hSpCas9 negative selection 10228140
67428573 67428596 11 + 28162770 P31FUJ viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.4522473417004895 [162] [139] -4 hSpCas9 negative selection 10228141
67428560 67428583 11 + 28162770 P31FUJ viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.35673302609660174 [104] [157] 4 hSpCas9 negative selection 10228142
67428602 67428625 11 + 28162770 P31FUJ viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.47555233879381753 [225] [190] -4 hSpCas9 negative selection 10228143
67429123 67429146 11 + 28162770 TF1 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 NaN [NaN] [315] 1 hSpCas9 negative selection 10397505
67428991 67429014 11 - 28162770 TF1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 NaN [NaN] [314] 1 hSpCas9 negative selection 10397506
67428573 67428596 11 + 28162770 TF1 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 NaN [NaN] [128] 1 hSpCas9 negative selection 10397507
67428560 67428583 11 + 28162770 TF1 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 NaN [NaN] [100] 1 hSpCas9 negative selection 10397508
67428602 67428625 11 + 28162770 TF1 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 NaN [NaN] [149] 1 hSpCas9 negative selection 10397509
67429123 67429146 11 + 28162770 SKM1 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.808581182259684 [106] [107] -6 hSpCas9 negative selection 10566871
67428991 67429014 11 - 28162770 SKM1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.7502497509495967 [37] [112] 7 hSpCas9 negative selection 10566872
67428573 67428596 11 + 28162770 SKM1 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.7950346504217363 [52] [53] -5 hSpCas9 negative selection 10566873
67428560 67428583 11 + 28162770 SKM1 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.677569311468506 [28] [81] 6 hSpCas9 negative selection 10566874
67428602 67428625 11 + 28162770 SKM1 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.5224414161630976 [38] [47] -4 hSpCas9 negative selection 10566875
67429123 67429146 11 + 28162770 SKM1 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.808581182259684 [106] [107] -6 hSpCas9 negative selection 10736237
67428991 67429014 11 - 28162770 SKM1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.7502497509495967 [37] [112] 7 hSpCas9 negative selection 10736238
67428573 67428596 11 + 28162770 SKM1 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.7950346504217363 [52] [53] -5 hSpCas9 negative selection 10736239
67428560 67428583 11 + 28162770 SKM1 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.677569311468506 [28] [81] 6 hSpCas9 negative selection 10736240
67428602 67428625 11 + 28162770 SKM1 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.5224414161630976 [38] [47] -4 hSpCas9 negative selection 10736241
67429123 67429146 11 + 28162770 PL21 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.017337316433011285 [292] [125] 0 hSpCas9 negative selection 10905603
67428991 67429014 11 - 28162770 PL21 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.2309456612704947 [138] [70] 2 hSpCas9 negative selection 10905604
67428573 67428596 11 + 28162770 PL21 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.8482234070720788 [272] [65] -5 hSpCas9 negative selection 10905605
67428560 67428583 11 + 28162770 PL21 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -1.2420827141157538 [124] [22] -7 hSpCas9 negative selection 10905606
67428602 67428625 11 + 28162770 PL21 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 1.5189617985088608 [92] [115] 9 hSpCas9 negative selection 10905607
67429123 67429146 11 + 28162770 P31FUJ viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.6467919456796298 [280] [516] 7 hSpCas9 negative selection 11074969
67428991 67429014 11 - 28162770 P31FUJ viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.49266933116948947 [181] [151] -4 hSpCas9 negative selection 11074970
67428573 67428596 11 + 28162770 P31FUJ viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.4522473417004895 [162] [139] -4 hSpCas9 negative selection 11074971
67428560 67428583 11 + 28162770 P31FUJ viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.35673302609660174 [104] [157] 4 hSpCas9 negative selection 11074972
67428602 67428625 11 + 28162770 P31FUJ viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.47555233879381753 [225] [190] -4 hSpCas9 negative selection 11074973
67429123 67429146 11 + 28162770 OCIAML5 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.05548718037140793 [144] [271] 0 hSpCas9 negative selection 11244335
67428991 67429014 11 - 28162770 OCIAML5 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.3345319976631316 [145] [208] -2 hSpCas9 negative selection 11244336
67428573 67428596 11 + 28162770 OCIAML5 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.43323749242277904 [94] [126] -3 hSpCas9 negative selection 11244337
67428560 67428583 11 + 28162770 OCIAML5 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -0.524012373179793 [46] [58] -4 hSpCas9 negative selection 11244338
67428602 67428625 11 + 28162770 OCIAML5 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 0.6255123944835598 [78] [219] 5 hSpCas9 negative selection 11244339
67429123 67429146 11 + 28162770 EOL1 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.3188296748952494 [553] [233] -2 hSpCas9 negative selection 11413701
67428991 67429014 11 - 28162770 EOL1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.2341499744485237 [191] [85] -2 hSpCas9 negative selection 11413702
67428573 67428596 11 + 28162770 EOL1 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -1.1321666194237867 [440] [105] -6 hSpCas9 negative selection 11413703
67428560 67428583 11 + 28162770 EOL1 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.39552344244323584 [214] [148] 3 hSpCas9 negative selection 11413704
67428602 67428625 11 + 28162770 EOL1 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 0.2046556907632699 [195] [118] 1 hSpCas9 negative selection 11413705
67429123 67429146 11 + 28162770 MOLM13 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.15237998791253016 [454] [295] -1 hSpCas9 negative selection 11583067
67428991 67429014 11 - 28162770 MOLM13 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.33131632866913496 [154] [140] 2 hSpCas9 negative selection 11583068
67428573 67428596 11 + 28162770 MOLM13 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.9915422370927185 [362] [131] -5 hSpCas9 negative selection 11583069
67428560 67428583 11 + 28162770 MOLM13 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.07435295147665705 [221] [168] 0 hSpCas9 negative selection 11583070
67428602 67428625 11 + 28162770 MOLM13 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.5413291484848 [156] [77] -3 hSpCas9 negative selection 11583071
67429123 67429146 11 + 28162770 HEL viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.4715183472573231 [393] [181] -3 hSpCas9 negative selection 11752433
67428991 67429014 11 - 28162770 HEL viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 0.450093754057961 [175] [153] 4 hSpCas9 negative selection 11752434
67428573 67428596 11 + 28162770 HEL viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.5458018476093023 [350] [153] -4 hSpCas9 negative selection 11752435
67428560 67428583 11 + 28162770 HEL viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -0.06508041650633256 [146] [89] 0 hSpCas9 negative selection 11752436
67428602 67428625 11 + 28162770 HEL viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.06027943024251148 [139] [85] 0 hSpCas9 negative selection 11752437
67429123 67429146 11 + 28162770 MV411 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.4753894974611239 [221] [259] 4 hSpCas9 negative selection 11921799
67428991 67429014 11 - 28162770 MV411 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.2733946125186653 [131] [91] -2 hSpCas9 negative selection 11921800
67428573 67428596 11 + 28162770 MV411 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -1.4612603183606259 [218] [66] -7 hSpCas9 negative selection 11921801
67428560 67428583 11 + 28162770 MV411 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -0.26381526375537157 [123] [86] -2 hSpCas9 negative selection 11921802
67428602 67428625 11 + 28162770 MV411 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.1048641931481058 [119] [93] -1 hSpCas9 negative selection 11921803
67429123 67429146 11 + 28162770 MONOMAC1 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.7894588885906988 [160] [318] 7 hSpCas9 negative selection 12091165
67428991 67429014 11 - 28162770 MONOMAC1 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 2.1857368030483357 [64] [338] 9 hSpCas9 negative selection 12091166
67428573 67428596 11 + 28162770 MONOMAC1 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 0.3963378934778025 [113] [171] 4 hSpCas9 negative selection 12091167
67428560 67428583 11 + 28162770 MONOMAC1 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 0.8447833286350732 [84] [174] 7 hSpCas9 negative selection 12091168
67428602 67428625 11 + 28162770 MONOMAC1 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 0.5965122754730199 [74] [129] 6 hSpCas9 negative selection 12091169
67429123 67429146 11 + 28162770 OCIAML2 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 -0.45974150909942496 [65] [265] -4 hSpCas9 negative selection 12260531
67428991 67429014 11 - 28162770 OCIAML2 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 1.0566171776227076 [16] [195] 8 hSpCas9 negative selection 12260532
67428573 67428596 11 + 28162770 OCIAML2 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.7882015150853876 [61] [198] -5 hSpCas9 negative selection 12260533
67428560 67428583 11 + 28162770 OCIAML2 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -0.04916605680388447 [27] [149] 0 hSpCas9 negative selection 12260534
67428602 67428625 11 + 28162770 OCIAML2 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -0.07831240246340088 [23] [125] 0 hSpCas9 negative selection 12260535
67429123 67429146 11 + 28162770 OCIAML3 viability TGTGGGACACTATGAAGAGGTGG RPS6KB2 ENSG00000175634 0.23817256076801185 [106] [380] 2 hSpCas9 negative selection 12429897
67428991 67429014 11 - 28162770 OCIAML3 viability GCTGCCCTCAACTCGGCAAGGGG RPS6KB2 ENSG00000175634 -0.2633623283356916 [32] [82] -2 hSpCas9 negative selection 12429898
67428573 67428596 11 + 28162770 OCIAML3 viability GAGACGGAGGAAGGCAGCGAGGG RPS6KB2 ENSG00000175634 -0.6225767925209341 [50] [99] -5 hSpCas9 negative selection 12429899
67428560 67428583 11 + 28162770 OCIAML3 viability TGATTTGGATTTGGAGACGGAGG RPS6KB2 ENSG00000175634 -0.3309732344903695 [39] [95] -3 hSpCas9 negative selection 12429900
67428602 67428625 11 + 28162770 OCIAML3 viability CGAGCCAGAGCTCAGCCCCGCGG RPS6KB2 ENSG00000175634 -1.009045139603007 [29] [44] -6 hSpCas9 negative selection 12429901