Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 861
• Symbol: RUNX1
• Description: RUNX family transcription factor 1

DataSource: http://genomecrispr.dkfz.de/#!/results/RUNX1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
34887061	34887084	21	+	26472758	Jiyoye	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.0968352608937228	[123]	[99]	0	hSpCas9	negative selection	141271
34886934	34886957	21	-	26472758	Jiyoye	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-1.4360991148066735	[60]	[16]	-7	hSpCas9	negative selection	141272
34887031	34887054	21	-	26472758	Jiyoye	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-0.2808806121793863	[57]	[35]	-2	hSpCas9	negative selection	141273
34886881	34886904	21	+	26472758	Jiyoye	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-1.7385020736897618	[176]	[39]	-8	hSpCas9	negative selection	141274
34859495	34859518	21	-	26472758	Jiyoye	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-3.274648658467872	[76]	[5]	-9	hSpCas9	negative selection	141275
34834564	34834587	21	-	26472758	Jiyoye	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	0.20459621395257832	[228]	[198]	1	hSpCas9	negative selection	141276
34887019	34887042	21	-	26472758	Jiyoye	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.7291034763932358	[9]	[24]	8	hSpCas9	negative selection	141277
34886973	34886996	21	-	26472758	Jiyoye	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-0.3363330585271048	[220]	[131]	-2	hSpCas9	negative selection	141278
34886956	34886979	21	-	26472758	Jiyoye	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-2.0591426227166636	[104]	[18]	-8	hSpCas9	negative selection	141279
34886947	34886970	21	+	26472758	Jiyoye	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	141280
34887061	34887084	21	+	26472758	KBM7	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.6040015380356211	[304,207]	[64,89]	-5	hSpCas9	negative selection	332389
34886934	34886957	21	-	26472758	KBM7	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-5.791547207621428	[282,182]	[2,0]	-9	hSpCas9	negative selection	332390
34887031	34887054	21	-	26472758	KBM7	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-2.1200477711471417	[389,268]	[22,45]	-8	hSpCas9	negative selection	332391
34886881	34886904	21	+	26472758	KBM7	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-4.781291464165267	[588,490]	[14,3]	-9	hSpCas9	negative selection	332392
34859495	34859518	21	-	26472758	KBM7	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.564829162201308	[109,107]	[4,11]	-9	hSpCas9	negative selection	332393
34834564	34834587	21	-	26472758	KBM7	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.3817449741827175	[1106,808]	[237,110]	-7	hSpCas9	negative selection	332394
34887019	34887042	21	-	26472758	KBM7	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.7538058271522903	[101,156]	[144,69]	8	hSpCas9	negative selection	332395
34886973	34886996	21	-	26472758	KBM7	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.1354232514994094	[591,610]	[80,172]	-7	hSpCas9	negative selection	332396
34886956	34886979	21	-	26472758	KBM7	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-2.5229978857488096	[392,440]	[15,50]	-9	hSpCas9	negative selection	332397
34886947	34886970	21	+	26472758	KBM7	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.28075290439480005	[122,62]	[6,59]	-3	hSpCas9	negative selection	332398
34887061	34887084	21	+	26472758	Raji	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.2210403171691665	[121]	[32]	2	hSpCas9	negative selection	523507
34886934	34886957	21	-	26472758	Raji	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	1.043253197953884	[91]	[43]	8	hSpCas9	negative selection	523508
34887031	34887054	21	-	26472758	Raji	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-0.9640788271830246	[268]	[31]	-6	hSpCas9	negative selection	523509
34886881	34886904	21	+	26472758	Raji	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	0.2537730223551227	[205]	[56]	2	hSpCas9	negative selection	523510
34859495	34859518	21	-	26472758	Raji	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	0.10738353537359946	[71]	[17]	1	hSpCas9	negative selection	523511
34834564	34834587	21	-	26472758	Raji	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	0.5780499035061462	[406]	[140]	5	hSpCas9	negative selection	523512
34887019	34887042	21	-	26472758	Raji	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3082962292995959	[86]	[24]	3	hSpCas9	negative selection	523513
34886973	34886996	21	-	26472758	Raji	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-0.44319597132189303	[538]	[91]	-4	hSpCas9	negative selection	523514
34886956	34886979	21	-	26472758	Raji	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-1.2997918461322742	[243]	[22]	-7	hSpCas9	negative selection	523515
34886947	34886970	21	+	26472758	Raji	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	0.0030468755588639596	[42]	[9]	0	hSpCas9	negative selection	523516
34887061	34887084	21	+	26472758	K562	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.4850814162531937	[256]	[154]	-3	hSpCas9	negative selection	714625
34886934	34886957	21	-	26472758	K562	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-1.3522255781023447	[123]	[40]	-6	hSpCas9	negative selection	714626
34887031	34887054	21	-	26472758	K562	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	0.7985202646828424	[251]	[369]	6	hSpCas9	negative selection	714627
34886881	34886904	21	+	26472758	K562	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-0.5565099252317242	[391]	[224]	-3	hSpCas9	negative selection	714628
34859495	34859518	21	-	26472758	K562	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.8960624958833834	[96]	[10]	-8	hSpCas9	negative selection	714629
34834564	34834587	21	-	26472758	K562	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.1121023070454563	[611]	[238]	-6	hSpCas9	negative selection	714630
34887019	34887042	21	-	26472758	K562	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3784360756381344	[112]	[123]	3	hSpCas9	negative selection	714631
34886973	34886996	21	-	26472758	K562	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-0.4513617636863161	[540]	[333]	-3	hSpCas9	negative selection	714632
34886956	34886979	21	-	26472758	K562	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-1.0874248360859982	[364]	[144]	-5	hSpCas9	negative selection	714633
34886947	34886970	21	+	26472758	K562	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.7555812723335533	[65]	[32]	-4	hSpCas9	negative selection	714634
34799344	34799367	21	+	26627737	DLD1	viability	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.6204841065786055	[680]	[313,390,285]	6	hSpCas9	negative selection	816102
34834565	34834588	21	-	26627737	DLD1	viability	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.6687895519277348	[566]	[334,232,275]	6	hSpCas9	negative selection	816103
34859518	34859541	21	+	26627737	DLD1	viability	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.3882582144427973	[853]	[209,502,342]	4	hSpCas9	negative selection	816104
34880562	34880585	21	-	26627737	DLD1	viability	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	1.0240936973082815	[908]	[802,806,192]	8	hSpCas9	negative selection	816105
34887019	34887042	21	-	26627737	DLD1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.4136214853710585	[90]	[1,55,53]	4	hSpCas9	negative selection	816106
35048847	35048870	21	+	26627737	DLD1	viability	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.21393814222146723	[1142]	[463,554,254]	2	hSpCas9	negative selection	816107
34799344	34799367	21	+	26627737	GBM cells	viability after 5 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.24683717830599217	[285]	[115,247]	4	hSpCas9	negative selection	898417
34834565	34834588	21	-	26627737	GBM cells	viability after 5 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.26221240419290814	[439]	[223,341]	4	hSpCas9	negative selection	898418
34859518	34859541	21	+	26627737	GBM cells	viability after 5 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.22718349664687498	[453]	[291,277]	3	hSpCas9	negative selection	898419
34880562	34880585	21	-	26627737	GBM cells	viability after 5 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.3106567962520961	[547]	[366,361]	5	hSpCas9	negative selection	898420
34887019	34887042	21	-	26627737	GBM cells	viability after 5 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.8685402258421671	[23]	[9,36]	9	hSpCas9	negative selection	898421
35048847	35048870	21	+	26627737	GBM cells	viability after 5 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.17111572353348592	[400]	[153,227]	-3	hSpCas9	negative selection	898422
34799344	34799367	21	+	26627737	GBM cells	viability after 13 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.5468630089537212	[285]	[245,210]	6	hSpCas9	negative selection	980732
34834565	34834588	21	-	26627737	GBM cells	viability after 13 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.823048697513862	[439]	[439,407]	8	hSpCas9	negative selection	980733
34859518	34859541	21	+	26627737	GBM cells	viability after 13 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.12302854189544832	[453]	[302,239]	1	hSpCas9	negative selection	980734
34880562	34880585	21	-	26627737	GBM cells	viability after 13 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.27845605959236464	[547]	[385,339]	3	hSpCas9	negative selection	980735
34887019	34887042	21	-	26627737	GBM cells	viability after 13 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.0668812531151177	[23]	[34,20]	9	hSpCas9	negative selection	980736
35048847	35048870	21	+	26627737	GBM cells	viability after 13 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.2501417417833116	[400]	[271,247]	3	hSpCas9	negative selection	980737
34799344	34799367	21	+	26627737	GBM cells	viability after 21 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.7547024175317996	[285]	[269,254]	7	hSpCas9	negative selection	1063047
34834565	34834588	21	-	26627737	GBM cells	viability after 21 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	1.3361101082334865	[439]	[661,549]	9	hSpCas9	negative selection	1063048
34859518	34859541	21	+	26627737	GBM cells	viability after 21 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.5868414714166951	[453]	[394,347]	6	hSpCas9	negative selection	1063049
34880562	34880585	21	-	26627737	GBM cells	viability after 21 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.7258881682522267	[547]	[482,500]	7	hSpCas9	negative selection	1063050
34887019	34887042	21	-	26627737	GBM cells	viability after 21 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.7913922268609808	[23]	[20,23]	7	hSpCas9	negative selection	1063051
35048847	35048870	21	+	26627737	GBM cells	viability after 21 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.6240900763501215	[400]	[352,319]	6	hSpCas9	negative selection	1063052
34799344	34799367	21	+	26627737	RPE1	viability after 9 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.7493547467634698	[1253]	[607,726]	5	hSpCas9	negative selection	1145362
34834565	34834588	21	-	26627737	RPE1	viability after 9 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	1.8761003637417946	[660]	[577,993]	8	hSpCas9	negative selection	1145363
34859518	34859541	21	+	26627737	RPE1	viability after 9 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.48166444747774695	[1866]	[992,587]	3	hSpCas9	negative selection	1145364
34880562	34880585	21	-	26627737	RPE1	viability after 9 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.6125422326939514	[2121]	[851,1226]	4	hSpCas9	negative selection	1145365
34887019	34887042	21	-	26627737	RPE1	viability after 9 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.8173335833839008	[76]	[125,31]	8	hSpCas9	negative selection	1145366
35048847	35048870	21	+	26627737	RPE1	viability after 9 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.4885782407634192	[1009]	[423,468]	3	hSpCas9	negative selection	1145367
34799344	34799367	21	+	26627737	RPE1	viability after 12 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.763084498918835	[1253]	[563,579]	5	hSpCas9	negative selection	1227677
34834565	34834588	21	-	26627737	RPE1	viability after 12 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	2.3735877630791764	[660]	[845,998]	9	hSpCas9	negative selection	1227678
34859518	34859541	21	+	26627737	RPE1	viability after 12 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.6800415376453732	[1866]	[1063,527]	4	hSpCas9	negative selection	1227679
34880562	34880585	21	-	26627737	RPE1	viability after 12 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	1.08050645650247	[2121]	[1227,1181]	6	hSpCas9	negative selection	1227680
34887019	34887042	21	-	26627737	RPE1	viability after 12 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.8219699489206325	[76]	[77,67]	8	hSpCas9	negative selection	1227681
35048847	35048870	21	+	26627737	RPE1	viability after 12 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.2718967119680751	[1009]	[215,233]	-2	hSpCas9	negative selection	1227682
34799344	34799367	21	+	26627737	RPE1	viability after 15 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.7897241630389045	[1253]	[599,625]	5	hSpCas9	negative selection	1309992
34834565	34834588	21	-	26627737	RPE1	viability after 15 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	2.468301059571661	[660]	[795,1264]	9	hSpCas9	negative selection	1309993
34859518	34859541	21	+	26627737	RPE1	viability after 15 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	1.034329192632338	[1866]	[1435,739]	6	hSpCas9	negative selection	1309994
34880562	34880585	21	-	26627737	RPE1	viability after 15 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	1.0024533968471434	[2121]	[1141,1260]	6	hSpCas9	negative selection	1309995
34887019	34887042	21	-	26627737	RPE1	viability after 15 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.2029904254891561	[76]	[41,57]	7	hSpCas9	negative selection	1309996
35048847	35048870	21	+	26627737	RPE1	viability after 15 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.1512039625847283	[1009]	[357,277]	1	hSpCas9	negative selection	1309997
34799344	34799367	21	+	26627737	RPE1	viability after 18 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.8629116836763819	[1253]	[745,475]	5	hSpCas9	negative selection	1392307
34834565	34834588	21	-	26627737	RPE1	viability after 18 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	2.698433716395063	[660]	[1168,1145]	9	hSpCas9	negative selection	1392308
34859518	34859541	21	+	26627737	RPE1	viability after 18 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	1.1777762195423949	[1866]	[1513,739]	6	hSpCas9	negative selection	1392309
34880562	34880585	21	-	26627737	RPE1	viability after 18 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	1.0207300995166497	[2121]	[1056,1273]	6	hSpCas9	negative selection	1392310
34887019	34887042	21	-	26627737	RPE1	viability after 18 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.8952516922979028	[76]	[85,67]	8	hSpCas9	negative selection	1392311
35048847	35048870	21	+	26627737	RPE1	viability after 18 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.024356527841612796	[1009]	[326,223]	0	hSpCas9	negative selection	1392312
34799344	34799367	21	+	26627737	HeLa	viability after 8 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.08720191465302615	[455]	[291,69,282]	0	hSpCas9	negative selection	1474622
34834565	34834588	21	-	26627737	HeLa	viability after 8 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.8495133256581362	[527]	[368,551,317]	7	hSpCas9	negative selection	1474623
34859518	34859541	21	+	26627737	HeLa	viability after 8 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.3577144573397766	[1193]	[337,479,384]	-3	hSpCas9	negative selection	1474624
34880562	34880585	21	-	26627737	HeLa	viability after 8 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	-0.6261515474351289	[1196]	[379,307,333]	-6	hSpCas9	negative selection	1474625
34887019	34887042	21	-	26627737	HeLa	viability after 8 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	4.9237227008667945	[0]	[19,20,0]	9	hSpCas9	negative selection	1474626
35048847	35048870	21	+	26627737	HeLa	viability after 8 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.18167897992144083	[364]	[142,86,293]	1	hSpCas9	negative selection	1474627
34799344	34799367	21	+	26627737	HeLa	viability after 12 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.1769163902910902	[455]	[477,413,388]	8	hSpCas9	negative selection	1556937
34834565	34834588	21	-	26627737	HeLa	viability after 12 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.42013999013294645	[527]	[332,207,344]	3	hSpCas9	negative selection	1556938
34859518	34859541	21	+	26627737	HeLa	viability after 12 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.3606189654839762	[1193]	[265,284,608]	-3	hSpCas9	negative selection	1556939
34880562	34880585	21	-	26627737	HeLa	viability after 12 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	-0.13907822813276693	[1196]	[540,489,314]	-1	hSpCas9	negative selection	1556940
34887019	34887042	21	-	26627737	HeLa	viability after 12 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	6.917031488507601	[0]	[3,63,78]	9	hSpCas9	negative selection	1556941
35048847	35048870	21	+	26627737	HeLa	viability after 12 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	1.0868333204512963	[364]	[356,303,302]	7	hSpCas9	negative selection	1556942
34799344	34799367	21	+	26627737	HeLa	viability after 15 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.125890709707759	[455]	[279,531,404]	7	hSpCas9	negative selection	1639252
34834565	34834588	21	-	26627737	HeLa	viability after 15 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.8022176177610536	[527]	[479,305,333]	6	hSpCas9	negative selection	1639253
34859518	34859541	21	+	26627737	HeLa	viability after 15 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.4719643885577478	[1193]	[280,266,516]	-4	hSpCas9	negative selection	1639254
34880562	34880585	21	-	26627737	HeLa	viability after 15 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	-0.1581328012930716	[1196]	[264,469,588]	-1	hSpCas9	negative selection	1639255
34887019	34887042	21	-	26627737	HeLa	viability after 15 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	5.329397352516507	[0]	[10,35,0]	9	hSpCas9	negative selection	1639256
35048847	35048870	21	+	26627737	HeLa	viability after 15 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	1.0455017467499945	[364]	[33,481,415]	7	hSpCas9	negative selection	1639257
34799344	34799367	21	+	26627737	HeLa	viability after 18 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.1334162010230129	[455]	[173,462,404]	7	hSpCas9	negative selection	1721567
34834565	34834588	21	-	26627737	HeLa	viability after 18 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.7891679871267419	[527]	[306,263,333]	6	hSpCas9	negative selection	1721568
34859518	34859541	21	+	26627737	HeLa	viability after 18 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.5329330538163422	[1193]	[173,203,516]	-5	hSpCas9	negative selection	1721569
34880562	34880585	21	-	26627737	HeLa	viability after 18 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	-0.16484670687839298	[1196]	[177,383,588]	-1	hSpCas9	negative selection	1721570
34887019	34887042	21	-	26627737	HeLa	viability after 18 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	5.263207229658722	[0]	[4,30,0]	9	hSpCas9	negative selection	1721571
35048847	35048870	21	+	26627737	HeLa	viability after 18 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	1.090498205363245	[364]	[28,414,415]	7	hSpCas9	negative selection	1721572
34799344	34799367	21	+	26627737	HCT116	viability after 6 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.08514617934580176	[853]	[173,124]	0	hSpCas9	negative selection	1803882
34834565	34834588	21	-	26627737	HCT116	viability after 6 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	2.031617068029787	[911]	[1407,132]	8	hSpCas9	negative selection	1803883
34859518	34859541	21	+	26627737	HCT116	viability after 6 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.19888834249826617	[717]	[106,141]	1	hSpCas9	negative selection	1803884
34880562	34880585	21	-	26627737	HCT116	viability after 6 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.43365498370387534	[959]	[509,34]	2	hSpCas9	negative selection	1803885
34887019	34887042	21	-	26627737	HCT116	viability after 6 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	2.4278377092348173	[38]	[90,0]	9	hSpCas9	negative selection	1803886
35048847	35048870	21	+	26627737	HCT116	viability after 6 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.02375128924722434	[638]	[141,74]	0	hSpCas9	negative selection	1803887
34799344	34799367	21	+	26627737	HCT116	viability after 8 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	-0.012722653285343943	[557]	[273,353,285]	0	hSpCas9	negative selection	1886197
34834565	34834588	21	-	26627737	HCT116	viability after 8 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.04727374787750127	[508]	[307,239,266]	0	hSpCas9	negative selection	1886198
34859518	34859541	21	+	26627737	HCT116	viability after 8 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.13548979968446528	[472]	[257,283,170]	-1	hSpCas9	negative selection	1886199
34880562	34880585	21	-	26627737	HCT116	viability after 8 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.2760668751334321	[676]	[477,374,501]	3	hSpCas9	negative selection	1886200
34887019	34887042	21	-	26627737	HCT116	viability after 8 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.7927044597537072	[14]	[17,8,15]	7	hSpCas9	negative selection	1886201
35048847	35048870	21	+	26627737	HCT116	viability after 8 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.14081606319424494	[393]	[300,162,254]	1	hSpCas9	negative selection	1886202
34799344	34799367	21	+	26627737	HCT116	viability after 9 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.334971062298231	[853]	[314,265]	2	hSpCas9	negative selection	1968512
34834565	34834588	21	-	26627737	HCT116	viability after 9 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.11254996920063931	[911]	[231,287]	0	hSpCas9	negative selection	1968513
34859518	34859541	21	+	26627737	HCT116	viability after 9 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.17177826866912352	[717]	[91,231]	-1	hSpCas9	negative selection	1968514
34880562	34880585	21	-	26627737	HCT116	viability after 9 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.04799681059814043	[959]	[407,151]	0	hSpCas9	negative selection	1968515
34887019	34887042	21	-	26627737	HCT116	viability after 9 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.0497764076796132	[38]	[20,21]	7	hSpCas9	negative selection	1968516
35048847	35048870	21	+	26627737	HCT116	viability after 9 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.2929877280422719	[638]	[179,231]	2	hSpCas9	negative selection	1968517
34799344	34799367	21	+	26627737	HCT116	viability after 12 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.1619861779139663	[557]	[272,529,190]	1	hSpCas9	negative selection	2050827
34834565	34834588	21	-	26627737	HCT116	viability after 12 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.02731651617998898	[508]	[264,253,267]	0	hSpCas9	negative selection	2050828
34859518	34859541	21	+	26627737	HCT116	viability after 12 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.29159302724134867	[472]	[224,106,272]	-3	hSpCas9	negative selection	2050829
34880562	34880585	21	-	26627737	HCT116	viability after 12 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.48457388817554214	[676]	[405,519,575]	5	hSpCas9	negative selection	2050830
34887019	34887042	21	-	26627737	HCT116	viability after 12 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.8836303164285857	[14]	[25,6,53]	9	hSpCas9	negative selection	2050831
35048847	35048870	21	+	26627737	HCT116	viability after 12 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.18250507616098838	[393]	[205,214,285]	2	hSpCas9	negative selection	2050832
34799344	34799367	21	+	26627737	HCT116	viability after 15 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.2081313299204347	[557]	[447,464,208]	2	hSpCas9	negative selection	2133142
34834565	34834588	21	-	26627737	HCT116	viability after 15 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.24706788683689151	[508]	[382,162,209]	-3	hSpCas9	negative selection	2133143
34859518	34859541	21	+	26627737	HCT116	viability after 15 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.1726812994162415	[472]	[361,157,217]	-2	hSpCas9	negative selection	2133144
34880562	34880585	21	-	26627737	HCT116	viability after 15 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.20260716242468302	[676]	[365,489,475]	2	hSpCas9	negative selection	2133145
34887019	34887042	21	-	26627737	HCT116	viability after 15 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.4089891873868972	[14]	[0,44,19]	9	hSpCas9	negative selection	2133146
35048847	35048870	21	+	26627737	HCT116	viability after 15 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.6669416151237613	[393]	[357,475,244]	6	hSpCas9	negative selection	2133147
34799344	34799367	21	+	26627737	HCT116	viability after 18 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.2592768006134213	[557]	[273,433,249]	2	hSpCas9	negative selection	2215457
34834565	34834588	21	-	26627737	HCT116	viability after 18 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.31697695018796784	[508]	[227,78,297]	-3	hSpCas9	negative selection	2215458
34859518	34859541	21	+	26627737	HCT116	viability after 18 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.2983589588822872	[472]	[245,82,237]	-3	hSpCas9	negative selection	2215459
34880562	34880585	21	-	26627737	HCT116	viability after 18 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.4889356258761772	[676]	[344,471,564]	4	hSpCas9	negative selection	2215460
34887019	34887042	21	-	26627737	HCT116	viability after 18 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.8832755161825179	[14]	[0,10,28]	7	hSpCas9	negative selection	2215461
35048847	35048870	21	+	26627737	HCT116	viability after 18 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.8021762798792238	[393]	[404,168,437]	6	hSpCas9	negative selection	2215462
34886959	34886982	21	-	24336569	HL60	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	-0.48242641469601744	[1155]	[1750]	-4	hSpCas9	negative selection	2293456
34886969	34886992	21	+	24336569	HL60	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	0.9343608665327863	[407]	[1649]	7	hSpCas9	negative selection	2293457
34886974	34886997	21	+	24336569	HL60	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	-0.3135666469107992	[645]	[1099]	-3	hSpCas9	negative selection	2293458
34886984	34887007	21	+	24336569	HL60	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	-0.9763473948146824	[171]	[184]	-7	hSpCas9	negative selection	2293459
34887018	34887041	21	-	24336569	HL60	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.18713211063501944	[1013]	[2442]	1	hSpCas9	negative selection	2293460
34887027	34887050	21	+	24336569	HL60	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	-0.033316304962258056	[441]	[913]	0	hSpCas9	negative selection	2293461
34887038	34887061	21	+	24336569	HL60	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	-0.4160488957984718	[1702]	[2700]	-4	hSpCas9	negative selection	2293462
34887045	34887068	21	-	24336569	HL60	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	-1.252782337371075	[1035]	[919]	-8	hSpCas9	negative selection	2293463
34887058	34887081	21	+	24336569	HL60	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	-0.1598666168029954	[500]	[948]	-1	hSpCas9	negative selection	2293464
34887071	34887094	21	+	24336569	HL60	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	0.4507869725796333	[510]	[1477]	4	hSpCas9	negative selection	2293465
34886959	34886982	21	-	24336569	KBM7	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	-2.410527980944721	[960]	[492]	-8	hSpCas9	negative selection	2360633
34886969	34886992	21	+	24336569	KBM7	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-0.5910479034768632	[411]	[745]	-5	hSpCas9	negative selection	2360634
34886974	34886997	21	+	24336569	KBM7	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	0.6892190252848348	[371]	[1635]	6	hSpCas9	negative selection	2360635
34886984	34887007	21	+	24336569	KBM7	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	0.3008820364551532	[74]	[251]	2	hSpCas9	negative selection	2360636
34887018	34887041	21	-	24336569	KBM7	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	-0.9932665485365989	[923]	[1265]	-6	hSpCas9	negative selection	2360637
34887027	34887050	21	+	24336569	KBM7	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	0.5101356581373186	[250]	[974]	5	hSpCas9	negative selection	2360638
34887038	34887061	21	+	24336569	KBM7	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	-1.6705941400269806	[1158]	[992]	-8	hSpCas9	negative selection	2360639
34887045	34887068	21	-	24336569	KBM7	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	-3.886607642394228	[666]	[122]	-9	hSpCas9	negative selection	2360640
34887058	34887081	21	+	24336569	KBM7	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	-3.14913945458389	[321]	[98]	-9	hSpCas9	negative selection	2360641
34887071	34887094	21	+	24336569	KBM7	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	-1.1953515456716715	[334]	[398]	-7	hSpCas9	negative selection	2360642
35436882	35436905	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAGCCTCGACTTCTTGG	RUNX1	ENSG00000159216	-0.3334344553746127	[914,176]	[125,59]	-1	dCas9-VP64	positive selection	2383775
34888777	34888800	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGGCCTGTGATTGGCCGCCGG	RUNX1	ENSG00000159216	-1.3427678835252879	[161,491]	[31,24]	-7	dCas9-VP64	positive selection	2385671
34888800	34888823	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCGCGCCCTGGCTGATACCGG	RUNX1	ENSG00000159216	-1.457804367812127	[104,92]	[4,9]	-8	dCas9-VP64	positive selection	2385672
34888825	34888848	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCCGCCGGCTCCTGGAATTGG	RUNX1	ENSG00000159216	-1.6128202266096014	[408,199]	[14,28]	-8	dCas9-VP64	positive selection	2385673
34862118	34862141	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGAGAGAGAGAGAGACTGAG	RUNX1	ENSG00000159216	2.1104589956690165	[17,51]	[55,8]	7	dCas9-VP64	positive selection	2385724
35908542	35908565	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTCCCAGACGTCGCCTATTGG	RUNX1	ENSG00000159216	3.0318284886162896	[188,93]	[437,56]	8	dCas9-VP64	positive selection	2385893
35301577	35301600	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCTGCCACTACGCCCGG	RUNX1	ENSG00000159216	0.535464235425859	[718,90]	[215,31]	2	dCas9-VP64	positive selection	2386866
35961722	35961745	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACAGTCTCACTCTGTCGCCCAGG	RUNX1	ENSG00000159216	-0.03251129179922707	[128,164]	[23,38]	0	dCas9-VP64	positive selection	2391369
35313966	35313989	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTCGG	RUNX1	ENSG00000159216	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398803
35746133	35746156	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTCTAATCCCAGCTACTCCGG	RUNX1	ENSG00000159216	-0.6235089132009077	[202,440]	[53,36]	-3	dCas9-VP64	positive selection	2400813
34982400	34982423	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGACGG	RUNX1	ENSG00000159216	2.740144461675261	[44,53]	[104,38]	8	dCas9-VP64	positive selection	2402705
35650331	35650354	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTAGCCGGGCGTAGTGGCAG	RUNX1	ENSG00000159216	-0.8514681672512537	[13,97]	[5,6]	-5	dCas9-VP64	positive selection	2404262
35912414	35912437	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGAGGTTTAACTGGCTGACGG	RUNX1	ENSG00000159216	-0.31260746452684585	[7,135]	[11,12]	-1	dCas9-VP64	positive selection	2411043
35594259	35594282	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCTACCTCCGCCTCCTGG	RUNX1	ENSG00000159216	0.2334890985798408	[352,717]	[86,194]	1	dCas9-VP64	positive selection	2411916
34874524	34874547	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTTGAACCTGGGAGGTGGAGG	RUNX1	ENSG00000159216	-1.7942305092270365	[61,1]	[0,1]	-8	dCas9-VP64	positive selection	2412434
35742266	35742289	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCACCAGG	RUNX1	ENSG00000159216	0.9550246130222104	[38,14]	[18,2]	4	dCas9-VP64	positive selection	2414114
35651958	35651981	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAAAAATACAAAGTTAGCCAGG	RUNX1	ENSG00000159216	0.3906432334662431	[10,116]	[2,33]	1	dCas9-VP64	positive selection	2417253
35285285	35285308	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCCTAG	RUNX1	ENSG00000159216	-0.5760906316419423	[119,210]	[24,22]	-3	dCas9-VP64	positive selection	2418424
35540478	35540501	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGTAGGCCAAGGTGGG	RUNX1	ENSG00000159216	0.5553943551630764	[8,10]	[3,1]	2	dCas9-VP64	positive selection	2418541
34863740	34863763	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGATGGGGTTTCACTATGTCAG	RUNX1	ENSG00000159216	-1.179364879940898	[327,34]	[27,4]	-6	dCas9-VP64	positive selection	2425461
35429504	35429527	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAATCTCTGCCTCCTAG	RUNX1	ENSG00000159216	0.009160240507729789	[175,457]	[15,128]	0	dCas9-VP64	positive selection	2425894
35049435	35049458	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACAGCCTGGGGGAGGGCAGGTGG	RUNX1	ENSG00000159216	1.3894865240952037	[16,94]	[9,57]	5	dCas9-VP64	positive selection	2428602
35049468	35049491	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCGAGTAGACTTTGCAAGAGG	RUNX1	ENSG00000159216	3.0641980695490183	[18,48]	[94,30]	8	dCas9-VP64	positive selection	2428603
35049448	35049471	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTATTTTCTTGCACAGCCTGGG	RUNX1	ENSG00000159216	-1.4568170427941354	[68,206]	[7,13]	-8	dCas9-VP64	positive selection	2428604
35313944	35313967	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACCGCGCCCAGCCAAG	RUNX1	ENSG00000159216	-0.6476236116882323	[118,215]	[30,13]	-3	dCas9-VP64	positive selection	2437992
35733535	35733558	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAACCCTGG	RUNX1	ENSG00000159216	-1.1949452889942442	[147,110]	[6,17]	-7	dCas9-VP64	positive selection	2450150
34871917	34871940	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCTGG	RUNX1	ENSG00000159216	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450543
35158740	35158763	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCTCTTGAACCCAAG	RUNX1	ENSG00000159216	0.7055876385115556	[3,484]	[1,182]	3	dCas9-VP64	positive selection	2452070
35554443	35554466	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCTTGTTAGCCAGGAAGG	RUNX1	ENSG00000159216	0.4876120141992475	[417,65]	[134,6]	2	dCas9-VP64	positive selection	2453041
35406711	35406734	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAAGATAGAGAGAAAGAGAGAG	RUNX1	ENSG00000159216	1.7770240872667666	[205,23]	[29,145]	6	dCas9-VP64	positive selection	2461124
35166260	35166283	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGAGAAAGAGAGAGAGAGAAG	RUNX1	ENSG00000159216	2.6984533978887146	[1,2]	[5,0]	8	dCas9-VP64	positive selection	2467657
35018148	35018171	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCCAG	RUNX1	ENSG00000159216	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468678
35682383	35682406	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCACCACTACACTCCAACCTAG	RUNX1	ENSG00000159216	3.4470194688704208	[182,212]	[207,766]	9	dCas9-VP64	positive selection	2471442
34989159	34989182	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGCGG	RUNX1	ENSG00000159216	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473430
35991666	35991689	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACTCCAGCCCGG	RUNX1	ENSG00000159216	-0.533989545843368	[184,280]	[23,46]	-3	dCas9-VP64	positive selection	2477419
35436882	35436905	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAGCCTCGACTTCTTGG	RUNX1	ENSG00000159216	-0.34054073104189286	[370,392]	[107,88]	-3	dCas9-VP64	positive selection	2479030
34888777	34888800	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGGCCTGTGATTGGCCGCCGG	RUNX1	ENSG00000159216	1.8237009270615867	[120,236]	[377,44]	8	dCas9-VP64	positive selection	2480926
34888800	34888823	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCGCGCCCTGGCTGATACCGG	RUNX1	ENSG00000159216	-0.7946754131303022	[215,109]	[37,23]	-7	dCas9-VP64	positive selection	2480927
34888825	34888848	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCCGCCGGCTCCTGGAATTGG	RUNX1	ENSG00000159216	-0.7020358814249825	[106,223]	[27,36]	-6	dCas9-VP64	positive selection	2480928
34862118	34862141	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGAGAGAGAGAGAGACTGAG	RUNX1	ENSG00000159216	-0.225908261769854	[83,548]	[38,131]	-2	dCas9-VP64	positive selection	2480979
35908542	35908565	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTCCCAGACGTCGCCTATTGG	RUNX1	ENSG00000159216	-0.06399642464480684	[122,149]	[43,40]	0	dCas9-VP64	positive selection	2481148
35301577	35301600	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCTGCCACTACGCCCGG	RUNX1	ENSG00000159216	-0.3318057288001406	[240,185]	[44,64]	-3	dCas9-VP64	positive selection	2482121
35961722	35961745	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACAGTCTCACTCTGTCGCCCAGG	RUNX1	ENSG00000159216	0.9050128823211769	[320,185]	[276,41]	6	dCas9-VP64	positive selection	2486624
35313966	35313989	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTCGG	RUNX1	ENSG00000159216	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2494058
35746133	35746156	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTCTAATCCCAGCTACTCCGG	RUNX1	ENSG00000159216	-0.3343030432183025	[506,132]	[127,41]	-3	dCas9-VP64	positive selection	2496068
34982400	34982423	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGACGG	RUNX1	ENSG00000159216	-0.0021690128549880505	[109,77]	[41,19]	0	dCas9-VP64	positive selection	2497960
35650331	35650354	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTAGCCGGGCGTAGTGGCAG	RUNX1	ENSG00000159216	0.40157018881037165	[169,39]	[83,8]	3	dCas9-VP64	positive selection	2499517
35912414	35912437	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGAGGTTTAACTGGCTGACGG	RUNX1	ENSG00000159216	0.3033984133535954	[163,49]	[44,41]	2	dCas9-VP64	positive selection	2506298
35594259	35594282	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCTACCTCCGCCTCCTGG	RUNX1	ENSG00000159216	1.897179644919835	[262,271]	[154,486]	8	dCas9-VP64	positive selection	2507171
34874524	34874547	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTTGAACCTGGGAGGTGGAGG	RUNX1	ENSG00000159216	1.9777309334960365	[57,27]	[33,74]	8	dCas9-VP64	positive selection	2507689
35742266	35742289	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCACCAGG	RUNX1	ENSG00000159216	-0.28279012529460834	[51,110]	[30,11]	-3	dCas9-VP64	positive selection	2509369
35651958	35651981	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAAAAATACAAAGTTAGCCAGG	RUNX1	ENSG00000159216	-0.2979935386794893	[181,221]	[40,64]	-3	dCas9-VP64	positive selection	2512508
35285285	35285308	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCCTAG	RUNX1	ENSG00000159216	-0.5911896850137947	[183,271]	[71,26]	-6	dCas9-VP64	positive selection	2513679
35540478	35540501	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGTAGGCCAAGGTGGG	RUNX1	ENSG00000159216	-0.8671691922358802	[189,124]	[32,22]	-7	dCas9-VP64	positive selection	2513796
34863740	34863763	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGATGGGGTTTCACTATGTCAG	RUNX1	ENSG00000159216	-1.0595412234634036	[295,89]	[39,20]	-8	dCas9-VP64	positive selection	2520716
35429504	35429527	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAATCTCTGCCTCCTAG	RUNX1	ENSG00000159216	0.1118552473866502	[131,312]	[53,99]	0	dCas9-VP64	positive selection	2521149
35049435	35049458	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACAGCCTGGGGGAGGGCAGGTGG	RUNX1	ENSG00000159216	1.5850742923650007	[8,74]	[5,72]	8	dCas9-VP64	positive selection	2523857
35049468	35049491	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCGAGTAGACTTTGCAAGAGG	RUNX1	ENSG00000159216	0.04621591406572628	[52,141]	[35,28]	0	dCas9-VP64	positive selection	2523858
35049448	35049471	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTATTTTCTTGCACAGCCTGGG	RUNX1	ENSG00000159216	-0.15050202938372134	[48,183]	[19,45]	-1	dCas9-VP64	positive selection	2523859
35313944	35313967	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACCGCGCCCAGCCAAG	RUNX1	ENSG00000159216	-0.5349507089340686	[327,308]	[84,58]	-5	dCas9-VP64	positive selection	2533247
35733535	35733558	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAACCCTGG	RUNX1	ENSG00000159216	1.2597172262171965	[381,372]	[459,141]	7	dCas9-VP64	positive selection	2545405
34871917	34871940	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCTGG	RUNX1	ENSG00000159216	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545798
35158740	35158763	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCTCTTGAACCCAAG	RUNX1	ENSG00000159216	-0.4319067453035411	[83,67]	[14,20]	-4	dCas9-VP64	positive selection	2547325
35554443	35554466	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCTTGTTAGCCAGGAAGG	RUNX1	ENSG00000159216	0.979205210014245	[130,109]	[16,134]	6	dCas9-VP64	positive selection	2548296
35406711	35406734	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAAGATAGAGAGAAAGAGAGAG	RUNX1	ENSG00000159216	-0.47521166952265065	[69,109]	[14,25]	-5	dCas9-VP64	positive selection	2556379
35166260	35166283	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGAGAAAGAGAGAGAGAGAAG	RUNX1	ENSG00000159216	0.2675505249358519	[97,40]	[28,25]	2	dCas9-VP64	positive selection	2562912
35018148	35018171	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCCAG	RUNX1	ENSG00000159216	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563933
35682383	35682406	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCACCACTACACTCCAACCTAG	RUNX1	ENSG00000159216	0.6976192756297284	[195,233]	[93,131]	5	dCas9-VP64	positive selection	2566697
34989159	34989182	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGCGG	RUNX1	ENSG00000159216	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568685
35991666	35991689	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACTCCAGCCCGG	RUNX1	ENSG00000159216	0.47261086320192236	[687,417]	[369,140]	4	dCas9-VP64	positive selection	2572674
34888332	34888355	21	-	27260157	DLD1	viability	TGCGTGGCAGTGTGCGTGGCAGG	RUNX1	ENSG00000159216	-1.00593490513235	[]	[]	-7	hSpCas9	negative selection	2573946
34887071	34887094	21	+	27260157	DLD1	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	-0.391919610034622	[]	[]	-3	hSpCas9	negative selection	2578227
34888357	34888380	21	+	27260157	DLD1	viability	CGCAACTTCACGGCTCGCCTCGG	RUNX1	ENSG00000159216	0.519221320189249	[]	[]	8	hSpCas9	negative selection	2579608
34887018	34887041	21	-	27260157	DLD1	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.813357708646764	[]	[]	9	hSpCas9	negative selection	2580940
34886969	34886992	21	+	27260157	DLD1	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-0.645429842181641	[]	[]	-5	hSpCas9	negative selection	2611283
34888347	34888370	21	+	27260157	DLD1	viability	GCCACGCACACGCAACTTCACGG	RUNX1	ENSG00000159216	0.505238961960902	[]	[]	8	hSpCas9	negative selection	2613205
34887038	34887061	21	+	27260157	DLD1	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	0.18530287344651	[]	[]	3	hSpCas9	negative selection	2614259
34887027	34887050	21	+	27260157	DLD1	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	0.698209288927023	[]	[]	8	hSpCas9	negative selection	2619216
35048838	35048861	21	+	27260157	DLD1	viability	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.645319744997633	[]	[]	8	hSpCas9	negative selection	2622504
34886984	34887007	21	+	27260157	DLD1	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	-0.16545007102883	[]	[]	-1	hSpCas9	negative selection	2623815
34887058	34887081	21	+	27260157	DLD1	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	-0.51147615197019	[]	[]	-4	hSpCas9	negative selection	2643529
34888291	34888314	21	+	27260157	DLD1	viability	CGAAACAGATCGGGCGGCTCGGG	RUNX1	ENSG00000159216	0.595632970841276	[]	[]	8	hSpCas9	negative selection	2644276
34886959	34886982	21	-	27260157	DLD1	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	1.70404884096866	[]	[]	9	hSpCas9	negative selection	2644284
34886974	34886997	21	+	27260157	DLD1	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	1.43188820804852	[]	[]	9	hSpCas9	negative selection	2644769
34888596	34888619	21	+	27260157	DLD1	viability	AAAGAAGTGCCTGGCGGCGCAGG	RUNX1	ENSG00000159216	0.987813958295816	[]	[]	9	hSpCas9	negative selection	2646999
34887045	34887068	21	-	27260157	DLD1	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	0.547677966150829	[]	[]	8	hSpCas9	negative selection	2647640
34888590	34888613	21	-	27260157	DLD1	viability	CCGCCAGGCACTTCTTTCCGGGG	RUNX1	ENSG00000159216	0.35689677908938	[]	[]	4	hSpCas9	negative selection	2647832
34888348	34888371	21	-	27260157	DLD1	viability	GCCGTGAAGTTGCGTGTGCGTGG	RUNX1	ENSG00000159216	0.64336306641916	[]	[]	8	hSpCas9	negative selection	2648842
34888332	34888355	21	-	27260157	HT1080	viability	TGCGTGGCAGTGTGCGTGGCAGG	RUNX1	ENSG00000159216	-0.948262822031067	[]	[]	-8	hSpCas9	negative selection	2650076
34887071	34887094	21	+	27260157	HT1080	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	-0.199023469492145	[]	[]	0	hSpCas9	negative selection	2654357
34888357	34888380	21	+	27260157	HT1080	viability	CGCAACTTCACGGCTCGCCTCGG	RUNX1	ENSG00000159216	1.14996289169252	[]	[]	8	hSpCas9	negative selection	2655738
34887018	34887041	21	-	27260157	HT1080	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.271370605392414	[]	[]	2	hSpCas9	negative selection	2657070
34886969	34886992	21	+	27260157	HT1080	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-0.719536822457913	[]	[]	-8	hSpCas9	negative selection	2687413
34888347	34888370	21	+	27260157	HT1080	viability	GCCACGCACACGCAACTTCACGG	RUNX1	ENSG00000159216	0.589468850034213	[]	[]	5	hSpCas9	negative selection	2689335
34887038	34887061	21	+	27260157	HT1080	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	0.413752535197813	[]	[]	4	hSpCas9	negative selection	2690389
34887027	34887050	21	+	27260157	HT1080	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	0.854766713824122	[]	[]	7	hSpCas9	negative selection	2695346
35048838	35048861	21	+	27260157	HT1080	viability	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.910664583593785	[]	[]	7	hSpCas9	negative selection	2698634
34886984	34887007	21	+	27260157	HT1080	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	0.0247811801371788	[]	[]	0	hSpCas9	negative selection	2699945
34887058	34887081	21	+	27260157	HT1080	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.0571912446712513	[]	[]	0	hSpCas9	negative selection	2719659
34888291	34888314	21	+	27260157	HT1080	viability	CGAAACAGATCGGGCGGCTCGGG	RUNX1	ENSG00000159216	0.819998755278322	[]	[]	7	hSpCas9	negative selection	2720406
34886959	34886982	21	-	27260157	HT1080	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	2.02755085464435	[]	[]	9	hSpCas9	negative selection	2720414
34886974	34886997	21	+	27260157	HT1080	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	-0.0847112223175733	[]	[]	0	hSpCas9	negative selection	2720899
34888596	34888619	21	+	27260157	HT1080	viability	AAAGAAGTGCCTGGCGGCGCAGG	RUNX1	ENSG00000159216	0.466280856384482	[]	[]	4	hSpCas9	negative selection	2723129
34887045	34887068	21	-	27260157	HT1080	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	-0.607406921717426	[]	[]	-8	hSpCas9	negative selection	2723770
34888590	34888613	21	-	27260157	HT1080	viability	CCGCCAGGCACTTCTTTCCGGGG	RUNX1	ENSG00000159216	-0.152934144820123	[]	[]	0	hSpCas9	negative selection	2723962
34888348	34888371	21	-	27260157	HT1080	viability	GCCGTGAAGTTGCGTGTGCGTGG	RUNX1	ENSG00000159216	0.695995252538706	[]	[]	6	hSpCas9	negative selection	2724972
34888332	34888355	21	-	27260157	MKN45	viability	TGCGTGGCAGTGTGCGTGGCAGG	RUNX1	ENSG00000159216	-1.11989416802261	[]	[]	-8	hSpCas9	negative selection	2726206
34887071	34887094	21	+	27260157	MKN45	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	-0.291107252633518	[]	[]	-1	hSpCas9	negative selection	2730487
34888357	34888380	21	+	27260157	MKN45	viability	CGCAACTTCACGGCTCGCCTCGG	RUNX1	ENSG00000159216	1.30947425001936	[]	[]	9	hSpCas9	negative selection	2731868
34887018	34887041	21	-	27260157	MKN45	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.896686441158558	[]	[]	8	hSpCas9	negative selection	2733200
34886969	34886992	21	+	27260157	MKN45	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-1.28863736604647	[]	[]	-8	hSpCas9	negative selection	2763543
34888347	34888370	21	+	27260157	MKN45	viability	GCCACGCACACGCAACTTCACGG	RUNX1	ENSG00000159216	0.620520004220336	[]	[]	7	hSpCas9	negative selection	2765465
34887038	34887061	21	+	27260157	MKN45	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	0.707638898443379	[]	[]	7	hSpCas9	negative selection	2766519
34887027	34887050	21	+	27260157	MKN45	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	1.12990810887469	[]	[]	8	hSpCas9	negative selection	2771476
35048838	35048861	21	+	27260157	MKN45	viability	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.00952001573612058	[]	[]	0	hSpCas9	negative selection	2774764
34886984	34887007	21	+	27260157	MKN45	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	0.129505089352178	[]	[]	4	hSpCas9	negative selection	2776075
34887058	34887081	21	+	27260157	MKN45	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.550793964850649	[]	[]	7	hSpCas9	negative selection	2795789
34888291	34888314	21	+	27260157	MKN45	viability	CGAAACAGATCGGGCGGCTCGGG	RUNX1	ENSG00000159216	0.421017199179939	[]	[]	6	hSpCas9	negative selection	2796536
34886959	34886982	21	-	27260157	MKN45	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	2.1708191890564	[]	[]	9	hSpCas9	negative selection	2796544
34886974	34886997	21	+	27260157	MKN45	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	0.0223277199870426	[]	[]	0	hSpCas9	negative selection	2797029
34888596	34888619	21	+	27260157	MKN45	viability	AAAGAAGTGCCTGGCGGCGCAGG	RUNX1	ENSG00000159216	1.63940849947068	[]	[]	9	hSpCas9	negative selection	2799259
34887045	34887068	21	-	27260157	MKN45	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	0.212622248878576	[]	[]	5	hSpCas9	negative selection	2799900
34888590	34888613	21	-	27260157	MKN45	viability	CCGCCAGGCACTTCTTTCCGGGG	RUNX1	ENSG00000159216	-0.311878673939839	[]	[]	-1	hSpCas9	negative selection	2800092
34888348	34888371	21	-	27260157	MKN45	viability	GCCGTGAAGTTGCGTGTGCGTGG	RUNX1	ENSG00000159216	0.399874849241957	[]	[]	6	hSpCas9	negative selection	2801102
34888332	34888355	21	-	27260157	RKO	viability	TGCGTGGCAGTGTGCGTGGCAGG	RUNX1	ENSG00000159216	-0.756485809785417	[]	[]	-7	hSpCas9	negative selection	2802336
34887071	34887094	21	+	27260157	RKO	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	-0.182951677668619	[]	[]	-1	hSpCas9	negative selection	2806617
34888357	34888380	21	+	27260157	RKO	viability	CGCAACTTCACGGCTCGCCTCGG	RUNX1	ENSG00000159216	0.759093527116078	[]	[]	8	hSpCas9	negative selection	2807998
34887018	34887041	21	-	27260157	RKO	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.637960279830017	[]	[]	3	hSpCas9	negative selection	2809330
34886969	34886992	21	+	27260157	RKO	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-0.220410168127392	[]	[]	-1	hSpCas9	negative selection	2839673
34888347	34888370	21	+	27260157	RKO	viability	GCCACGCACACGCAACTTCACGG	RUNX1	ENSG00000159216	0.539290811450299	[]	[]	3	hSpCas9	negative selection	2841595
34887038	34887061	21	+	27260157	RKO	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	1.09077382859346	[]	[]	9	hSpCas9	negative selection	2842649
34887027	34887050	21	+	27260157	RKO	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	0.887648551790546	[]	[]	8	hSpCas9	negative selection	2847606
35048838	35048861	21	+	27260157	RKO	viability	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.90561650535886	[]	[]	8	hSpCas9	negative selection	2850894
34886984	34887007	21	+	27260157	RKO	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	-0.488173519472329	[]	[]	-6	hSpCas9	negative selection	2852205
34887058	34887081	21	+	27260157	RKO	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.203875530293056	[]	[]	1	hSpCas9	negative selection	2871919
34888291	34888314	21	+	27260157	RKO	viability	CGAAACAGATCGGGCGGCTCGGG	RUNX1	ENSG00000159216	0.229473702379755	[]	[]	1	hSpCas9	negative selection	2872666
34886959	34886982	21	-	27260157	RKO	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	2.30680338829423	[]	[]	9	hSpCas9	negative selection	2872674
34886974	34886997	21	+	27260157	RKO	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	1.08539772229396	[]	[]	9	hSpCas9	negative selection	2873159
34888596	34888619	21	+	27260157	RKO	viability	AAAGAAGTGCCTGGCGGCGCAGG	RUNX1	ENSG00000159216	1.06756131048515	[]	[]	9	hSpCas9	negative selection	2875389
34887045	34887068	21	-	27260157	RKO	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	-0.547497053008585	[]	[]	-7	hSpCas9	negative selection	2876030
34888590	34888613	21	-	27260157	RKO	viability	CCGCCAGGCACTTCTTTCCGGGG	RUNX1	ENSG00000159216	0.4298794453814	[]	[]	2	hSpCas9	negative selection	2876222
34888348	34888371	21	-	27260157	RKO	viability	GCCGTGAAGTTGCGTGTGCGTGG	RUNX1	ENSG00000159216	0.469452758154096	[]	[]	2	hSpCas9	negative selection	2877232
34888332	34888355	21	-	27260157	SF268	viability	TGCGTGGCAGTGTGCGTGGCAGG	RUNX1	ENSG00000159216	-0.516660076128493	[]	[]	-4	hSpCas9	negative selection	2878466
34887071	34887094	21	+	27260157	SF268	viability	CGTGAAGCGGCGGCTCGTGCTGG	RUNX1	ENSG00000159216	0.388613433478399	[]	[]	4	hSpCas9	negative selection	2882747
34888357	34888380	21	+	27260157	SF268	viability	CGCAACTTCACGGCTCGCCTCGG	RUNX1	ENSG00000159216	1.6200710312709	[]	[]	9	hSpCas9	negative selection	2884128
34887018	34887041	21	-	27260157	SF268	viability	ATGAGCGAGGCGTTGCCGCTGGG	RUNX1	ENSG00000159216	0.932808771965581	[]	[]	9	hSpCas9	negative selection	2885460
34886969	34886992	21	+	27260157	SF268	viability	GTCGCCGCTCCTCAGCTTGCCGG	RUNX1	ENSG00000159216	-0.683998386900701	[]	[]	-5	hSpCas9	negative selection	2915803
34888347	34888370	21	+	27260157	SF268	viability	GCCACGCACACGCAACTTCACGG	RUNX1	ENSG00000159216	0.486147156358948	[]	[]	7	hSpCas9	negative selection	2917725
34887038	34887061	21	+	27260157	SF268	viability	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	1.00945405993474	[]	[]	9	hSpCas9	negative selection	2918779
34887027	34887050	21	+	27260157	SF268	viability	AACGCCTCGCTCATCTTGCCTGG	RUNX1	ENSG00000159216	0.336586829882446	[]	[]	4	hSpCas9	negative selection	2923736
35048838	35048861	21	+	27260157	SF268	viability	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.880600602862423	[]	[]	9	hSpCas9	negative selection	2927024
34886984	34887007	21	+	27260157	SF268	viability	CTTGCCGGCCAGGGCAGCGCCGG	RUNX1	ENSG00000159216	0.811067106094385	[]	[]	8	hSpCas9	negative selection	2928335
34887058	34887081	21	+	27260157	SF268	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.0129163622226448	[]	[]	0	hSpCas9	negative selection	2948049
34888291	34888314	21	+	27260157	SF268	viability	CGAAACAGATCGGGCGGCTCGGG	RUNX1	ENSG00000159216	0.136104765328248	[]	[]	0	hSpCas9	negative selection	2948796
34886959	34886982	21	-	27260157	SF268	viability	GAGGAGCGGCGACCGCAGCATGG	RUNX1	ENSG00000159216	2.44845899429257	[]	[]	9	hSpCas9	negative selection	2948804
34886974	34886997	21	+	27260157	SF268	viability	CGCTCCTCAGCTTGCCGGCCAGG	RUNX1	ENSG00000159216	-0.7517224560463	[]	[]	-6	hSpCas9	negative selection	2949289
34888596	34888619	21	+	27260157	SF268	viability	AAAGAAGTGCCTGGCGGCGCAGG	RUNX1	ENSG00000159216	0.970308418459832	[]	[]	9	hSpCas9	negative selection	2951519
34887045	34887068	21	-	27260157	SF268	viability	CCTTCCACCGCGCTGAGCCCAGG	RUNX1	ENSG00000159216	0.827612493491678	[]	[]	8	hSpCas9	negative selection	2952160
34888590	34888613	21	-	27260157	SF268	viability	CCGCCAGGCACTTCTTTCCGGGG	RUNX1	ENSG00000159216	0.126343219677851	[]	[]	0	hSpCas9	negative selection	2952352
34888348	34888371	21	-	27260157	SF268	viability	GCCGTGAAGTTGCGTGTGCGTGG	RUNX1	ENSG00000159216	0.282129381962128	[]	[]	4	hSpCas9	negative selection	2953362
34887039	34887062	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	0.5495609032656326	[3,3]	[3,5]	9	hSpCas9	positive selection	3018342
34886948	34886971	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.03928412916101354	[2,2]	[3,0]	0	hSpCas9	positive selection	3018343
34886836	34886859	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	0.19195704731074786	[3,3]	[3,2]	4	hSpCas9	positive selection	3018344
34887083	34887106	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	-0.5645400420547502	[4,4]	[3,1]	-7	hSpCas9	positive selection	3018345
34887039	34887062	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	-0.0729120047323461	[3,3]	[3,1]	-1	hSpCas9	positive selection	3086200
34886948	34886971	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.5427806636176407	[2,2]	[0,0]	-7	hSpCas9	positive selection	3086201
34886836	34886859	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	0.05118888799020731	[3,3]	[1,2]	0	hSpCas9	positive selection	3086202
34887083	34887106	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	-0.10616772769491681	[4,4]	[2,2]	-1	hSpCas9	positive selection	3086203
34892924	34892947		-	24336571	A375	resistance to PLX after 7 days	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.08143680652631205	[10,10]	[9,9]	-2	hSpCas9	positive selection	3142231
34892921	34892944		+	24336571	A375	resistance to PLX after 7 days	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.14406803058040796	[8,10]	[10,10]	4	hSpCas9	positive selection	3142232
34880563	34880586		+	24336571	A375	resistance to PLX after 7 days	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.2025700624117024	[20,18]	[14,18]	-6	hSpCas9	positive selection	3142234
34859490	34859513		+	24336571	A375	resistance to PLX after 7 days	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	-0.12471884444275128	[21,20]	[19,18]	-4	hSpCas9	positive selection	3142235
35048841	35048864		-	24336571	A375	resistance to PLX after 7 days	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	-0.41472767283995815	[27,24]	[19,18]	-9	hSpCas9	positive selection	3142236
34880602	34880625		-	24336571	A375	resistance to PLX after 7 days	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.14965150244968617	[24,20]	[20,18]	-5	hSpCas9	positive selection	3142237
35048838	35048861		+	24336571	A375	resistance to PLX after 7 days	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.08521716800806192	[13,12]	[15,11]	3	hSpCas9	positive selection	3142238
34892924	34892947		-	24336571	A375	resistance to PLX after 14 days	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.04937241692750999	[13,6]	[3,4]	0	hSpCas9	positive selection	3200024
34892921	34892944		+	24336571	A375	resistance to PLX after 14 days	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.2714720239393896	[9,20]	[8,8]	2	hSpCas9	positive selection	3200025
34880563	34880586		+	24336571	A375	resistance to PLX after 14 days	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.9979037459910476	[33,21]	[25,25]	7	hSpCas9	positive selection	3200027
34859490	34859513		+	24336571	A375	resistance to PLX after 14 days	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	-0.3668445743152634	[16,22]	[4,7]	-4	hSpCas9	positive selection	3200028
35048841	35048864		-	24336571	A375	resistance to PLX after 14 days	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	-0.9355592475029426	[31,23]	[6,5]	-9	hSpCas9	positive selection	3200029
34880602	34880625		-	24336571	A375	resistance to PLX after 14 days	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.4689661623758845	[26,32]	[17,19]	4	hSpCas9	positive selection	3200030
35048838	35048861		+	24336571	A375	resistance to PLX after 14 days	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	-1.0050855967774708	[10,22]	[3,2]	-9	hSpCas9	positive selection	3200031
34892924	34892947		-	24336571	A375	viability after 7 days	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.03112844886834365	[11]	[10,10]	0	hSpCas9	negative selection	3257817
34892921	34892944		+	24336571	A375	viability after 7 days	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.1951765403468414	[8]	[8,10]	3	hSpCas9	negative selection	3257818
34880563	34880586		+	24336571	A375	viability after 7 days	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.10126013994269756	[22]	[20,18]	-1	hSpCas9	negative selection	3257820
34859490	34859513		+	24336571	A375	viability after 7 days	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	0.4851174279810188	[15]	[21,20]	7	hSpCas9	negative selection	3257821
35048841	35048864		-	24336571	A375	viability after 7 days	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	0.6765083459424313	[16]	[27,24]	8	hSpCas9	negative selection	3257822
34880602	34880625		-	24336571	A375	viability after 7 days	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.6347680388978906	[14]	[24,20]	8	hSpCas9	negative selection	3257823
35048838	35048861		+	24336571	A375	viability after 7 days	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	-0.360445875438131	[17]	[13,12]	-5	hSpCas9	negative selection	3257824
34892924	34892947		-	24336571	A375	viability after 14 days	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.03562904212425652	[11]	[13,6]	0	hSpCas9	negative selection	3315610
34892921	34892944		+	24336571	A375	viability after 14 days	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.8409597104040798	[8]	[9,20]	9	hSpCas9	negative selection	3315611
34880563	34880586		+	24336571	A375	viability after 14 days	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.39370014741168746	[22]	[33,21]	5	hSpCas9	negative selection	3315613
34859490	34859513		+	24336571	A375	viability after 14 days	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	0.41010416447965786	[15]	[16,22]	5	hSpCas9	negative selection	3315614
35048841	35048864		-	24336571	A375	viability after 14 days	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	0.7823433601572458	[16]	[31,23]	8	hSpCas9	negative selection	3315615
34880602	34880625		-	24336571	A375	viability after 14 days	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.0402368924496388	[14]	[26,32]	9	hSpCas9	negative selection	3315616
35048838	35048861		+	24336571	A375	viability after 14 days	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	-0.021275531261340686	[17]	[10,22]	0	hSpCas9	negative selection	3315617
34892924	34892947	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.9174762085612103	[80,80]	[0,0]	4	hSpCas9	positive selection	3390940
34880602	34880625	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.19123702098806272	[133,133]	[0,0]	1	hSpCas9	positive selection	3390941
34892921	34892944	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.3265888738829487	[121,121]	[0,0]	1	hSpCas9	positive selection	3390942
34887038	34887061	21	+	26780180	HT29	viability (Avana library 4 designs)	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	1.06358978290768	[]	[]	4	hSpCas9	negative selection	3456732
34886947	34886970	21	+	26780180	HT29	viability (Avana library 4 designs)	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	0.089262562751519	[]	[]	0	hSpCas9	negative selection	3456733
34886835	34886858	21	+	26780180	HT29	viability (Avana library 4 designs)	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	3.08016895490959	[]	[]	8	hSpCas9	negative selection	3456734
34887082	34887105	21	+	26780180	HT29	viability (Avana library 4 designs)	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	0.478203546951529	[]	[]	1	hSpCas9	negative selection	3456735
34887038	34887061	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	8.90379353969099	[]	[]	9	hSpCas9	negative selection	3555351
34886835	34886858	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	3.44255982065624	[]	[]	5	hSpCas9	negative selection	3555352
34887082	34887105	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	7.09460899889696	[]	[]	9	hSpCas9	negative selection	3555353
34886947	34886970	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	3.36213025902291	[]	[]	5	hSpCas9	negative selection	3555354
34886881	34886904	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	7.94068394958693	[]	[]	9	hSpCas9	negative selection	3555355
34886975	34886998	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCTCAGCTTGCCGGCCAGGG	RUNX1	ENSG00000159216	6.67588244227316	[]	[]	9	hSpCas9	negative selection	3555356
34887038	34887061	21	+	26780180	A375	viability (Avana lentiGuide)	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	-7.7944734296722	[]	[]	-9	hSpCas9	negative selection	3664010
34886835	34886858	21	+	26780180	A375	viability (Avana lentiGuide)	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	-8.15849552088393	[]	[]	-9	hSpCas9	negative selection	3664011
34887082	34887105	21	+	26780180	A375	viability (Avana lentiGuide)	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	-8.23287842305894	[]	[]	-9	hSpCas9	negative selection	3664012
34886947	34886970	21	+	26780180	A375	viability (Avana lentiGuide)	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-2.3945688394652	[]	[]	-4	hSpCas9	negative selection	3664013
34886881	34886904	21	+	26780180	A375	viability (Avana lentiGuide)	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-8.02265834356037	[]	[]	-9	hSpCas9	negative selection	3664014
34886975	34886998	21	+	26780180	A375	viability (Avana lentiGuide)	GCTCCTCAGCTTGCCGGCCAGGG	RUNX1	ENSG00000159216	-3.55168894206639	[]	[]	-6	hSpCas9	negative selection	3664015
34887038	34887061	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	-0.011050142916669156	[4]	[4,4]	0	hSpCas9	positive selection	3772617
34886835	34886858	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	-0.5674733380856587	[4]	[2,2]	-7	hSpCas9	positive selection	3772618
34887082	34887105	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	0.28396459197813995	[4]	[5,5]	8	hSpCas9	positive selection	3772619
34886947	34886970	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.011223461014859382	[4]	[4,3]	0	hSpCas9	positive selection	3772620
34886881	34886904	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-0.38861726112573547	[3]	[3,1]	-5	hSpCas9	positive selection	3772621
34886975	34886998	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCTCAGCTTGCCGGCCAGGG	RUNX1	ENSG00000159216	-0.017656982669944116	[4]	[3,4]	0	hSpCas9	positive selection	3772622
34887038	34887061	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCTTGCCTGGGCTCAGCGCGG	RUNX1	ENSG00000159216	0.1539202853651414	[5]	[5,4]	3	hSpCas9	positive selection	3881224
34886835	34886858	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGTACCTTGAAAGCGATGGG	RUNX1	ENSG00000159216	-1.0255901700187102	[5]	[2,0]	-8	hSpCas9	positive selection	3881225
34887082	34887105	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCGTGCTGGCATCTACGGGG	RUNX1	ENSG00000159216	0.07472604013443435	[5]	[5,5]	1	hSpCas9	positive selection	3881226
34886947	34886970	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.38496234057368856	[4]	[3,2]	-5	hSpCas9	positive selection	3881227
34886881	34886904	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-0.6398464243878057	[4]	[2,0]	-7	hSpCas9	positive selection	3881228
34886975	34886998	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCTCAGCTTGCCGGCCAGGG	RUNX1	ENSG00000159216	-0.017809388285900903	[5]	[4,3]	0	hSpCas9	positive selection	3881229
34892924	34892947	21	-	26780180	A375	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	1.31012177467536	[]	[]	7	hSpCas9	negative selection	3991242
34892921	34892944	21	+	26780180	A375	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	1.44249816936587	[]	[]	8	hSpCas9	negative selection	3991243
34880563	34880586	21	+	26780180	A375	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.237567184609357	[]	[]	-6	hSpCas9	negative selection	3991244
34887058	34887081	21	+	26780180	A375	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.258236208015882	[]	[]	0	hSpCas9	negative selection	3991245
34887019	34887042	21	-	26780180	A375	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.887064113109126	[]	[]	4	hSpCas9	negative selection	3991246
34880602	34880625	21	-	26780180	A375	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.00933261169531	[]	[]	5	hSpCas9	negative selection	3991247
34892924	34892947	21	-	26780180	HT29	viability (GeCKOv2 library)	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	1.27138332537689	[]	[]	6	hSpCas9	negative selection	4099208
34892921	34892944	21	+	26780180	HT29	viability (GeCKOv2 library)	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	1.73432483745124	[]	[]	8	hSpCas9	negative selection	4099209
34880563	34880586	21	+	26780180	HT29	viability (GeCKOv2 library)	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.247817263061293	[]	[]	0	hSpCas9	negative selection	4099210
34887058	34887081	21	+	26780180	HT29	viability (GeCKOv2 library)	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.01110431427949	[]	[]	4	hSpCas9	negative selection	4099211
34887019	34887042	21	-	26780180	HT29	viability (GeCKOv2 library)	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.924210721672775	[]	[]	4	hSpCas9	negative selection	4099212
34880602	34880625	21	-	26780180	HT29	viability (GeCKOv2 library)	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.84291794803572	[]	[]	8	hSpCas9	negative selection	4099213
34892924	34892947	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.0152530938010072	[3]	[2,1]	0	hSpCas9	positive selection	4167953
34892921	34892944	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.23276688683984129	[3]	[1,3]	6	hSpCas9	positive selection	4167954
34880563	34880586	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.00010737439240571245	[4]	[0,4]	0	hSpCas9	positive selection	4167956
34859490	34859513	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	-0.030839522217751714	[4]	[2,2]	0	hSpCas9	positive selection	4167957
35048841	35048864	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	-0.3174628538409265	[4]	[1,2]	-7	hSpCas9	positive selection	4167958
34880602	34880625	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.36867991996536614	[3]	[2,4]	8	hSpCas9	positive selection	4167959
35048838	35048861	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	-0.33394671950832533	[3]	[1,1]	-7	hSpCas9	positive selection	4167960
34892924	34892947	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.8931102986033488	[4]	[1,3,1,4]	6	hSpCas9	positive selection	4231975
34892921	34892944	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.3786185482775261	[3]	[0,0,2,0]	-5	hSpCas9	positive selection	4231976
34880563	34880586	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	1.3004493116059077	[4]	[4,4,1,6]	9	hSpCas9	positive selection	4231978
34859490	34859513	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCATCCACTGTGATTTTGATGG	RUNX1	ENSG00000159216	0.18299266678833795	[3]	[2,0,4,0]	1	hSpCas9	positive selection	4231979
35048841	35048864	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCCACAGTGCTTCATGAGAGG	RUNX1	ENSG00000159216	0.8610545401505623	[4]	[2,2,1,4]	5	hSpCas9	positive selection	4231980
34880602	34880625	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.2736864061016038	[3]	[4,3,1,4]	9	hSpCas9	positive selection	4231981
35048838	35048861	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACCTCTCATGAAGCACTGTGG	RUNX1	ENSG00000159216	0.18102367709652056	[4]	[1,1,5,0]	1	hSpCas9	positive selection	4231982
34887019	34887042	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.11363283420256837	[3]	[3,1]	-2	hSpCas9	positive selection	4296085
34887058	34887081	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.1918712184675322	[1]	[1,0]	4	hSpCas9	positive selection	4296086
34880563	34880586	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.03595878672279712	[4]	[3,2]	0	hSpCas9	positive selection	4296087
34892924	34892947	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.3467692119326292	[2]	[1,0]	-6	hSpCas9	positive selection	4360339
34880602	34880625	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.30723547712473853	[2]	[1,0]	-6	hSpCas9	positive selection	4360340
34892921	34892944	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.24292519126673182	[2]	[2,1]	-5	hSpCas9	positive selection	4360341
34880564	34880586	21	+	27760321	OCIAML3	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.3156581828355285	[465,379]	[283,238]	-3	hSpCas9	negative selection	4436414
34880585	34880607	21	+	27760321	OCIAML3	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.10835155186832346	[300,226]	[251,179]	1	hSpCas9	negative selection	4436415
34880677	34880699	21	-	27760321	OCIAML3	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-0.3222997444569002	[715,674]	[368,521]	-3	hSpCas9	negative selection	4436416
34880700	34880722	21	-	27760321	OCIAML3	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-0.7909151917118307	[555,569]	[186,344]	-6	hSpCas9	negative selection	4436417
34886840	34886862	21	+	27760321	OCIAML3	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.8152728075043626	[827,716]	[295,402]	-6	hSpCas9	negative selection	4436418
34880564	34880586	21	+	27760321	OCIAML2	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-2.193336969796021	[465,379]	[51,103]	-9	hSpCas9	negative selection	4519877
34880585	34880607	21	+	27760321	OCIAML2	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	-1.0261909517768033	[300,226]	[103,103]	-7	hSpCas9	negative selection	4519878
34880677	34880699	21	-	27760321	OCIAML2	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-1.5347346028548274	[715,674]	[183,207]	-8	hSpCas9	negative selection	4519879
34880700	34880722	21	-	27760321	OCIAML2	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-1.7577269242997389	[555,569]	[117,157]	-9	hSpCas9	negative selection	4519880
34886840	34886862	21	+	27760321	OCIAML2	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-1.9825210599390362	[827,716]	[114,213]	-9	hSpCas9	negative selection	4519881
34880564	34880586	21	+	27760321	MV411	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.819957079703234	[465,379]	[60,301]	-5	hSpCas9	negative selection	4603340
34880585	34880607	21	+	27760321	MV411	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	-2.201151700683664	[300,226]	[5,84]	-8	hSpCas9	negative selection	4603341
34880677	34880699	21	-	27760321	MV411	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-3.3916212541001505	[715,674]	[6,98]	-9	hSpCas9	negative selection	4603342
34880700	34880722	21	-	27760321	MV411	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	0.7284915667611478	[555,569]	[413,924]	5	hSpCas9	negative selection	4603343
34886840	34886862	21	+	27760321	MV411	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-1.915711351402451	[827,716]	[83,210]	-8	hSpCas9	negative selection	4603344
34880564	34880586	21	+	27760321	HL60	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.6807070807888981	[465,379]	[163,267]	-6	hSpCas9	negative selection	4686803
34880585	34880607	21	+	27760321	HL60	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.771290734606223	[300,226]	[399,327]	8	hSpCas9	negative selection	4686804
34880677	34880699	21	-	27760321	HL60	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-0.0237552685637078	[715,674]	[520,599]	0	hSpCas9	negative selection	4686805
34880700	34880722	21	-	27760321	HL60	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	1.8094628799811012	[555,569]	[1782,1444]	9	hSpCas9	negative selection	4686806
34886840	34886862	21	+	27760321	HL60	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.9771625178931728	[827,716]	[243,399]	-7	hSpCas9	negative selection	4686807
34880564	34880586	21	+	27760321	HT1080	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	2.444416474727222	[379,296]	[692,778]	9	hSpCas9	negative selection	4770266
34880585	34880607	21	+	27760321	HT1080	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	2.541642404781798	[226,176]	[647,271]	9	hSpCas9	negative selection	4770267
34880677	34880699	21	-	27760321	HT1080	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	2.3034508934319335	[674,526]	[1263,1091]	9	hSpCas9	negative selection	4770268
34880700	34880722	21	-	27760321	HT1080	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	3.1623747564129876	[569,444]	[968,2730]	9	hSpCas9	negative selection	4770269
34886840	34886862	21	+	27760321	HT1080	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	2.963276304993297	[716,559]	[2506,1410]	9	hSpCas9	negative selection	4770270
34880564	34880586	21	+	27760321	HT29	viability after 7 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.39524695595269205	[379,296]	[571,463,676]	6	hSpCas9	negative selection	4853729
34880585	34880607	21	+	27760321	HT29	viability after 7 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.3367075912915759	[226,176]	[292,279,402]	5	hSpCas9	negative selection	4853730
34880677	34880699	21	-	27760321	HT29	viability after 7 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	0.1346002470627693	[674,526]	[1068,653,851]	2	hSpCas9	negative selection	4853731
34880700	34880722	21	-	27760321	HT29	viability after 7 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-0.33055300510282937	[569,444]	[580,534,450]	-5	hSpCas9	negative selection	4853732
34886840	34886862	21	+	27760321	HT29	viability after 7 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.5723573441181756	[716,559]	[715,540,425]	-7	hSpCas9	negative selection	4853733
34880564	34880586	21	+	27760321	HT29	viability after 25 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.15021077143899658	[379,296]	[271,511,522]	1	hSpCas9	negative selection	4937192
34880585	34880607	21	+	27760321	HT29	viability after 25 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.3953590647194906	[226,176]	[324,228,360]	4	hSpCas9	negative selection	4937193
34880677	34880699	21	-	27760321	HT29	viability after 25 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	0.19980856156361082	[674,526]	[976,747,609]	2	hSpCas9	negative selection	4937194
34880700	34880722	21	-	27760321	HT29	viability after 25 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	0.3184706380697433	[569,444]	[962,635,534]	3	hSpCas9	negative selection	4937195
34886840	34886862	21	+	27760321	HT29	viability after 25 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.16542631433521982	[716,559]	[665,564,726]	-2	hSpCas9	negative selection	4937196
34880564	34880586	21	+	27760321	HT29	viability after 22 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.618114388329921	[379,296]	[552,472,778]	7	hSpCas9	negative selection	5020655
34880585	34880607	21	+	27760321	HT29	viability after 22 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.3362741794081163	[226,176]	[446,167,264]	3	hSpCas9	negative selection	5020656
34880677	34880699	21	-	27760321	HT29	viability after 22 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	0.3201673646188211	[674,526]	[1014,1060,518]	3	hSpCas9	negative selection	5020657
34880700	34880722	21	-	27760321	HT29	viability after 22 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	0.03458476274077171	[569,444]	[828,432,533]	0	hSpCas9	negative selection	5020658
34886840	34886862	21	+	27760321	HT29	viability after 22 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.29825012766479975	[716,559]	[843,382,566]	-3	hSpCas9	negative selection	5020659
34880564	34880586	21	+	27760321	HT29	viability after 19 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.04262518679476624	[379,296]	[521,315,371]	0	hSpCas9	negative selection	5104118
34880585	34880607	21	+	27760321	HT29	viability after 19 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.09903124699892207	[226,176]	[241,210,286]	0	hSpCas9	negative selection	5104119
34880677	34880699	21	-	27760321	HT29	viability after 19 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-0.3022637710552984	[674,526]	[751,481,461]	-3	hSpCas9	negative selection	5104120
34880700	34880722	21	-	27760321	HT29	viability after 19 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-0.3671359006569553	[569,444]	[537,532,293]	-3	hSpCas9	negative selection	5104121
34886840	34886862	21	+	27760321	HT29	viability after 19 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	0.0691327508858226	[716,559]	[571,362,1320]	0	hSpCas9	negative selection	5104122
34880564	34880586	21	+	27760321	HT29	viability after 16 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.20004347410866935	[379,296]	[645,323,357]	2	hSpCas9	negative selection	5187581
34880585	34880607	21	+	27760321	HT29	viability after 16 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.09761088494722125	[226,176]	[210,182,329]	1	hSpCas9	negative selection	5187582
34880677	34880699	21	-	27760321	HT29	viability after 16 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	0.06398864398166815	[674,526]	[1000,617,519]	0	hSpCas9	negative selection	5187583
34880700	34880722	21	-	27760321	HT29	viability after 16 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	0.2662305616816536	[569,444]	[836,570,657]	3	hSpCas9	negative selection	5187584
34886840	34886862	21	+	27760321	HT29	viability after 16 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.3966623144207056	[716,559]	[770,253,631]	-4	hSpCas9	negative selection	5187585
34880564	34880586	21	+	27760321	HT29	viability after 13 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.4167959363397783	[379,296]	[731,430,415]	5	hSpCas9	negative selection	5271044
34880585	34880607	21	+	27760321	HT29	viability after 13 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	0.2828419629046347	[226,176]	[277,441,143]	3	hSpCas9	negative selection	5271045
34880677	34880699	21	-	27760321	HT29	viability after 13 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-0.019242226562068088	[674,526]	[655,788,622]	0	hSpCas9	negative selection	5271046
34880700	34880722	21	-	27760321	HT29	viability after 13 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-0.1539188431053563	[569,444]	[490,523,569]	-2	hSpCas9	negative selection	5271047
34886840	34886862	21	+	27760321	HT29	viability after 13 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.6362567436897041	[716,559]	[515,443,469]	-6	hSpCas9	negative selection	5271048
34880564	34880586	21	+	27760321	HT29	viability after 10 days	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.5649347587592457	[379,296]	[766,667,445]	7	hSpCas9	negative selection	5354507
34880585	34880607	21	+	27760321	HT29	viability after 10 days	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	-0.18174433560686531	[226,176]	[276,177,210]	-2	hSpCas9	negative selection	5354508
34880677	34880699	21	-	27760321	HT29	viability after 10 days	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	0.3241611041389437	[674,526]	[1029,894,892]	4	hSpCas9	negative selection	5354509
34880700	34880722	21	-	27760321	HT29	viability after 10 days	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	0.15876212655387978	[569,444]	[968,730,428]	2	hSpCas9	negative selection	5354510
34886840	34886862	21	+	27760321	HT29	viability after 10 days	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-0.1598790479415605	[716,559]	[707,721,710]	-2	hSpCas9	negative selection	5354511
34880564	34880586	21	+	27760321	MOLM13	viability	ACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-1.3415933212039841	[465,379]	[117,72]	-6	hSpCas9	negative selection	5437970
34880585	34880607	21	+	27760321	MOLM13	viability	GTCATTAAATCTTGCAACCTGG	RUNX1	ENSG00000159216	-4.143690605243316	[300,226]	[16,0]	-9	hSpCas9	negative selection	5437971
34880677	34880699	21	-	27760321	MOLM13	viability	GATGTTCCAGATGGCACTCTGG	RUNX1	ENSG00000159216	-2.7941658512608316	[715,674]	[54,57]	-8	hSpCas9	negative selection	5437972
34880700	34880722	21	-	27760321	MOLM13	viability	GTGTTTAGGTGGTGGCCCTAGG	RUNX1	ENSG00000159216	-1.5503318517602505	[555,569]	[109,107]	-7	hSpCas9	negative selection	5437973
34886840	34886862	21	+	27760321	MOLM13	viability	TACCTTGAAAGCGATGGGCAGG	RUNX1	ENSG00000159216	-1.4323338181011556	[827,716]	[260,75]	-7	hSpCas9	negative selection	5437974
35049141	35049164	21	-	27661255	K562	viability	GCATCACCAACCCACAGCCAAGG	RUNX1	ENSG00000159216	0.17430079639449597	[602,753]	[701,529]	6	dCas9-KRAB	negative selection	5508989
34887019	34887042	21	-	27260156	BXPC3	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3363033285571585	[467]	[603,653,552,658]	7	hSpCas9	negative selection	5568545
34887058	34887081	21	+	27260156	BXPC3	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.8318788813034517	[114]	[226,166,170,300]	9	hSpCas9	negative selection	5568546
34880563	34880586	21	+	27260156	BXPC3	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.7466732479380154	[1034]	[1700,1656,1760,2199]	9	hSpCas9	negative selection	5568547
34892924	34892947	21	-	27260156	BXPC3	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.0213663573290519	[232]	[210,248,289,207]	0	hSpCas9	negative selection	5632799
34880602	34880625	21	-	27260156	BXPC3	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.23349158605624232	[323]	[445,282,400,470]	5	hSpCas9	negative selection	5632800
34892921	34892944	21	+	27260156	BXPC3	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.08965462399165708	[374]	[353,360,378,380]	-2	hSpCas9	negative selection	5632801
34887019	34887042	21	-	27260156	A673	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.09326089039455138	[467]	[570,546,618,660]	2	hSpCas9	negative selection	5689796
34887058	34887081	21	+	27260156	A673	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.3656348823433564	[114]	[239,147,174,154]	8	hSpCas9	negative selection	5689797
34880563	34880586	21	+	27260156	A673	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.2462376562662989	[1034]	[1574,1432,1327,1576]	6	hSpCas9	negative selection	5689798
34892924	34892947	21	-	27260156	A673	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.21897720935681875	[232]	[376,293,351,282]	5	hSpCas9	negative selection	5754050
34880602	34880625	21	-	27260156	A673	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.12126632266159643	[323]	[427,306,467,495]	3	hSpCas9	negative selection	5754051
34892921	34892944	21	+	27260156	A673	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.021975856954323136	[374]	[529,423,400,427]	0	hSpCas9	negative selection	5754052
34887019	34887042	21	-	27260156	A375	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.6086670409204586	[467]	[594,1203,862,730]	8	hSpCas9	negative selection	5811047
34887058	34887081	21	+	27260156	A375	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.1446829507060927	[114]	[346,425,263,181]	9	hSpCas9	negative selection	5811048
34880563	34880586	21	+	27260156	A375	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	1.2210196233466835	[1034]	[2854,3709,2562,2317]	9	hSpCas9	negative selection	5811049
34892924	34892947	21	-	27260156	A375	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.20230634839730444	[232]	[346,278,300,318]	3	hSpCas9	negative selection	5875301
34880602	34880625	21	-	27260156	A375	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.65052376393453	[323]	[866,599,512,417]	8	hSpCas9	negative selection	5875302
34892921	34892944	21	+	27260156	A375	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.15993520216385526	[374]	[641,343,512,442]	2	hSpCas9	negative selection	5875303
34887019	34887042	21	-	27260156	COLO741	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.2577746164649959	[467]	[876,708,580]	5	hSpCas9	negative selection	5932298
34887058	34887081	21	+	27260156	COLO741	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.6336069507535886	[114]	[228,233,220]	9	hSpCas9	negative selection	5932299
34880563	34880586	21	+	27260156	COLO741	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.3313569509246099	[1034]	[1900,1602,1514]	7	hSpCas9	negative selection	5932300
34892924	34892947	21	-	27260156	COLO741	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.23453299238147118	[232]	[426,357,276]	5	hSpCas9	negative selection	5996552
34880602	34880625	21	-	27260156	COLO741	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.042281973719583754	[323]	[477,380,355]	-1	hSpCas9	negative selection	5996553
34892921	34892944	21	+	27260156	COLO741	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.10744694596391777	[374]	[409,561,562]	2	hSpCas9	negative selection	5996554
34887019	34887042	21	-	27260156	CAL120	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.08550748312293659	[467]	[800,624,457]	1	hSpCas9	negative selection	6053549
34887058	34887081	21	+	27260156	CAL120	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.3105426161748559	[114]	[275,83,186]	4	hSpCas9	negative selection	6053550
34880563	34880586	21	+	27260156	CAL120	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.38271252924171795	[1034]	[2051,1584,1459]	6	hSpCas9	negative selection	6053551
34892924	34892947	21	-	27260156	CAL120	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.36827961783825536	[232]	[377,527,219]	5	hSpCas9	negative selection	6117803
34880602	34880625	21	-	27260156	CAL120	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.0286621303478648	[323]	[772,385,88]	0	hSpCas9	negative selection	6117804
34892921	34892944	21	+	27260156	CAL120	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.28373914183433957	[374]	[793,377,565]	4	hSpCas9	negative selection	6117805
34887019	34887042	21	-	27260156	CADOES1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.2523008093946727	[467]	[530,546,574,416]	4	hSpCas9	negative selection	6174800
34887058	34887081	21	+	27260156	CADOES1	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.8685140018282291	[114]	[170,212,130,268]	9	hSpCas9	negative selection	6174801
34880563	34880586	21	+	27260156	CADOES1	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.2289539322718641	[1034]	[1230,997,1157,1124]	4	hSpCas9	negative selection	6174802
34892924	34892947	21	-	27260156	CADOES1	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.1196816438747843	[232]	[216,199,231,294]	2	hSpCas9	negative selection	6239054
34880602	34880625	21	-	27260156	CADOES1	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.42143380477063375	[323]	[607,391,331,276]	7	hSpCas9	negative selection	6239055
34892921	34892944	21	+	27260156	CADOES1	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.1761071016812793	[374]	[315,292,258,368]	-3	hSpCas9	negative selection	6239056
34887019	34887042	21	-	27260156	EWS502	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.18770741869170715	[467]	[562,555,488,653]	3	hSpCas9	negative selection	6296051
34887058	34887081	21	+	27260156	EWS502	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.8667389363235547	[114]	[145,233,236,283]	9	hSpCas9	negative selection	6296052
34880563	34880586	21	+	27260156	EWS502	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.45264925494718833	[1034]	[1498,1558,1338,1600]	7	hSpCas9	negative selection	6296053
34892924	34892947	21	-	27260156	EWS502	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.30203220200454883	[232]	[283,270,448,210]	5	hSpCas9	negative selection	6360305
34880602	34880625	21	-	27260156	EWS502	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.05317313928834916	[323]	[470,265,351,320]	0	hSpCas9	negative selection	6360306
34892921	34892944	21	+	27260156	EWS502	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.19395161894486956	[374]	[384,308,350,338]	-3	hSpCas9	negative selection	6360307
34887019	34887042	21	-	27260156	EW8	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3431491328237776	[467]	[508,450,534,421]	6	hSpCas9	negative selection	6417302
34887058	34887081	21	+	27260156	EW8	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.2734074235378423	[114]	[192,121,66,84]	5	hSpCas9	negative selection	6417303
34880563	34880586	21	+	27260156	EW8	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.301139216678314	[1034]	[1346,1116,888,837]	5	hSpCas9	negative selection	6417304
34892924	34892947	21	-	27260156	EW8	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.3837286334770429	[232]	[161,158,129,131]	-6	hSpCas9	negative selection	6481556
34880602	34880625	21	-	27260156	EW8	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.30528442778866816	[323]	[337,392,299,271]	5	hSpCas9	negative selection	6481557
34892921	34892944	21	+	27260156	EW8	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.16130162986018073	[374]	[501,462,229,200]	3	hSpCas9	negative selection	6481558
34887019	34887042	21	-	27260156	CORL105	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.22192039774252398	[467]	[769,562,776,473]	4	hSpCas9	negative selection	6538553
34887058	34887081	21	+	27260156	CORL105	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.9630984985891147	[114]	[232,218,416,204]	9	hSpCas9	negative selection	6538554
34880563	34880586	21	+	27260156	CORL105	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.3999773724964166	[1034]	[1557,1623,1607,1603]	7	hSpCas9	negative selection	6538555
34892924	34892947	21	-	27260156	CORL105	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.6135657368662286	[232]	[494,334,507,349]	9	hSpCas9	negative selection	6602807
34880602	34880625	21	-	27260156	CORL105	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.6664880839365849	[323]	[721,339,760,618]	9	hSpCas9	negative selection	6602808
34892921	34892944	21	+	27260156	CORL105	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.12322210679880485	[374]	[356,442,510,315]	-2	hSpCas9	negative selection	6602809
34887019	34887042	21	-	27260156	HS294T	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.04676740579316513	[467]	[210,158,107,227]	0	hSpCas9	negative selection	6659804
34887058	34887081	21	+	27260156	HS294T	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	-0.003468910309611495	[114]	[40,40,39,57]	0	hSpCas9	negative selection	6659805
34880563	34880586	21	+	27260156	HS294T	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.4569655146050211	[1034]	[158,296,369,363]	-6	hSpCas9	negative selection	6659806
34892924	34892947	21	-	27260156	HS294T	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.12598006822440022	[232]	[119,85,107,72]	1	hSpCas9	negative selection	6724058
34880602	34880625	21	-	27260156	HS294T	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.396877387503931	[323]	[98,246,115,207]	5	hSpCas9	negative selection	6724059
34892921	34892944	21	+	27260156	HS294T	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.02617081593631837	[374]	[194,109,152,124]	0	hSpCas9	negative selection	6724060
34887019	34887042	21	-	27260156	HCC44	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.10543975597266327	[467]	[711,229,908,542]	1	hSpCas9	negative selection	6781055
34887058	34887081	21	+	27260156	HCC44	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.5817568781326468	[114]	[169,176,269,173]	8	hSpCas9	negative selection	6781056
34880563	34880586	21	+	27260156	HCC44	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.030206289366515593	[1034]	[1103,859,1465,1234]	0	hSpCas9	negative selection	6781057
34892924	34892947	21	-	27260156	HCC44	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.40472083929548464	[232]	[276,289,357,466]	6	hSpCas9	negative selection	6845309
34880602	34880625	21	-	27260156	HCC44	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.18996889483717772	[323]	[351,382,465,472]	3	hSpCas9	negative selection	6845310
34892921	34892944	21	+	27260156	HCC44	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.054829618533019264	[374]	[665,305,494,343]	0	hSpCas9	negative selection	6845311
34887019	34887042	21	-	27260156	G402	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.22823042200469146	[467]	[509,422,577,438]	-3	hSpCas9	negative selection	6902306
34887058	34887081	21	+	27260156	G402	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	-0.23795801432159092	[114]	[64,174,91,137]	-3	hSpCas9	negative selection	6902307
34880563	34880586	21	+	27260156	G402	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.03534115024626305	[1034]	[1317,1262,1045,1307]	0	hSpCas9	negative selection	6902308
34892924	34892947	21	-	27260156	G402	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.006729210952924003	[232]	[221,210,277,400]	0	hSpCas9	negative selection	6966560
34880602	34880625	21	-	27260156	G402	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.4490218223116757	[323]	[452,467,382,821]	5	hSpCas9	negative selection	6966561
34892921	34892944	21	+	27260156	G402	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.16312313536357154	[374]	[547,371,342,388]	-2	hSpCas9	negative selection	6966562
34887019	34887042	21	-	27260156	L33	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.12776450665796818	[467]	[304,196,259,515]	-3	hSpCas9	negative selection	7023557
34887058	34887081	21	+	27260156	L33	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.6611667736946347	[114]	[156,53,115,253]	9	hSpCas9	negative selection	7023558
34880563	34880586	21	+	27260156	L33	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.20533740828276126	[1034]	[1368,434,746,1149]	4	hSpCas9	negative selection	7023559
34892924	34892947	21	-	27260156	L33	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.10586787787712593	[232]	[300,102,156,199]	2	hSpCas9	negative selection	7087811
34880602	34880625	21	-	27260156	L33	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.057652667476653985	[323]	[306,149,257,266]	1	hSpCas9	negative selection	7087812
34892921	34892944	21	+	27260156	L33	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.3567228667051403	[374]	[272,149,147,296]	-7	hSpCas9	negative selection	7087813
34887019	34887042	21	-	27260156	K562	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.2866706163272231	[467]	[267,440,434,228]	-4	hSpCas9	negative selection	7144808
34887058	34887081	21	+	27260156	K562	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.0328628639620225	[114]	[350,43,418,42]	9	hSpCas9	negative selection	7144809
34880563	34880586	21	+	27260156	K562	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.7977299090649616	[1034]	[403,168,488,967]	-7	hSpCas9	negative selection	7144810
34892924	34892947	21	-	27260156	K562	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.2259114271043401	[232]	[294,250,106,309]	3	hSpCas9	negative selection	7209062
34880602	34880625	21	-	27260156	K562	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.4625735512881832	[323]	[298,170,243,133]	-5	hSpCas9	negative selection	7209063
34892921	34892944	21	+	27260156	K562	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.2387845146352543	[374]	[329,237,452,125]	-3	hSpCas9	negative selection	7209064
34887019	34887042	21	-	27260156	HT29	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.2531556929662751	[467]	[782,669,784,498]	5	hSpCas9	negative selection	7266059
34887058	34887081	21	+	27260156	HT29	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.7216537603522089	[114]	[281,188,157,284]	9	hSpCas9	negative selection	7266060
34880563	34880586	21	+	27260156	HT29	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.3564746015804299	[1034]	[1543,1696,1673,1528]	7	hSpCas9	negative selection	7266061
34892924	34892947	21	-	27260156	HT29	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.05813555491327438	[232]	[304,258,449,175]	1	hSpCas9	negative selection	7330313
34880602	34880625	21	-	27260156	HT29	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.03731214760307211	[323]	[552,497,306,217]	-1	hSpCas9	negative selection	7330314
34892921	34892944	21	+	27260156	HT29	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.24844014332142228	[374]	[360,481,465,246]	-5	hSpCas9	negative selection	7330315
34887019	34887042	21	-	27260156	MHHES1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.10641591731324307	[467]	[693,461,474,366]	-2	hSpCas9	negative selection	7387310
34887058	34887081	21	+	27260156	MHHES1	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.7224226756987508	[114]	[343,275,169,106]	9	hSpCas9	negative selection	7387311
34880563	34880586	21	+	27260156	MHHES1	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.01216225864350462	[1034]	[1389,1432,1000,890]	0	hSpCas9	negative selection	7387312
34892924	34892947	21	-	27260156	MHHES1	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.532533389970099	[232]	[399,318,351,423]	8	hSpCas9	negative selection	7451564
34880602	34880625	21	-	27260156	MHHES1	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.18879852032245498	[323]	[492,481,388,326]	3	hSpCas9	negative selection	7451565
34892921	34892944	21	+	27260156	MHHES1	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.18562967346783465	[374]	[213,434,440,373]	-4	hSpCas9	negative selection	7451566
34887019	34887042	21	-	27260156	MEWO	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.013620522263479498	[467]	[482,407,442]	0	hSpCas9	negative selection	7508561
34887058	34887081	21	+	27260156	MEWO	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.4420758449884534	[114]	[164,169,106]	8	hSpCas9	negative selection	7508562
34880563	34880586	21	+	27260156	MEWO	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.2669418841522839	[1034]	[1268,1210,1034]	6	hSpCas9	negative selection	7508563
34892924	34892947	21	-	27260156	MEWO	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.20239719064015038	[232]	[288,207,262]	4	hSpCas9	negative selection	7572815
34880602	34880625	21	-	27260156	MEWO	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.32447435402455505	[323]	[235,237,250]	-6	hSpCas9	negative selection	7572816
34892921	34892944	21	+	27260156	MEWO	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.10435053161689933	[374]	[550,387,225]	2	hSpCas9	negative selection	7572817
34887019	34887042	21	-	27260156	LNCAPCLONEFGC	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.5310362556556332	[467]	[679,586,576,600]	8	hSpCas9	negative selection	7629812
34887058	34887081	21	+	27260156	LNCAPCLONEFGC	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.5468731439161965	[114]	[175,153,144,131]	8	hSpCas9	negative selection	7629813
34880563	34880586	21	+	27260156	LNCAPCLONEFGC	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.4079352138629069	[1034]	[1035,1062,1668,1285]	6	hSpCas9	negative selection	7629814
34892924	34892947	21	-	27260156	LNCAPCLONEFGC	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.516149961032973	[232]	[355,279,398,186]	7	hSpCas9	negative selection	7694066
34880602	34880625	21	-	27260156	LNCAPCLONEFGC	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.08669686100310586	[323]	[283,320,254,377]	1	hSpCas9	negative selection	7694067
34892921	34892944	21	+	27260156	LNCAPCLONEFGC	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.10397004680847655	[374]	[341,274,340,311]	-2	hSpCas9	negative selection	7694068
34887019	34887042	21	-	27260156	PANC0327	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3486381936655992	[467]	[581,589,575,365]	5	hSpCas9	negative selection	7751063
34887058	34887081	21	+	27260156	PANC0327	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.27390895894076994	[114]	[171,131,150,41]	4	hSpCas9	negative selection	7751064
34880563	34880586	21	+	27260156	PANC0327	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.14682993272444433	[1034]	[1189,508,647,1044]	-2	hSpCas9	negative selection	7751065
34892924	34892947	21	-	27260156	PANC0327	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.17973226647584595	[232]	[172,400,140,195]	2	hSpCas9	negative selection	7815317
34880602	34880625	21	-	27260156	PANC0327	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.015352213442109686	[323]	[382,290,161,309]	0	hSpCas9	negative selection	7815318
34892921	34892944	21	+	27260156	PANC0327	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.18625603338890473	[374]	[116,350,293,386]	-3	hSpCas9	negative selection	7815319
34887019	34887042	21	-	27260156	NCIH2009	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.4508692238180566	[467]	[936,743,1009]	6	hSpCas9	negative selection	7872314
34887058	34887081	21	+	27260156	NCIH2009	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.8426208109082878	[114]	[358,283,234]	9	hSpCas9	negative selection	7872315
34880563	34880586	21	+	27260156	NCIH2009	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.01827393184666115	[1034]	[1596,1363,1457]	0	hSpCas9	negative selection	7872316
34892924	34892947	21	-	27260156	NCIH2009	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.4666656430943579	[232]	[371,473,486]	6	hSpCas9	negative selection	7936568
34880602	34880625	21	-	27260156	NCIH2009	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.010198661841055112	[323]	[471,402,477]	0	hSpCas9	negative selection	7936569
34892921	34892944	21	+	27260156	NCIH2009	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.07214572807898256	[374]	[590,475,445]	-1	hSpCas9	negative selection	7936570
34887019	34887042	21	-	27260156	NCIH1373	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.1764939472328981	[467]	[2045,670,1564,157]	9	hSpCas9	negative selection	7993565
34887058	34887081	21	+	27260156	NCIH1373	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.9281817852848506	[114]	[536,615,88,192]	9	hSpCas9	negative selection	7993566
34880563	34880586	21	+	27260156	NCIH1373	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	1.2860777099738658	[1034]	[2061,2744,3081,873]	9	hSpCas9	negative selection	7993567
34892924	34892947	21	-	27260156	NCIH1373	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.795593040714967	[232]	[182,232,696,180]	7	hSpCas9	negative selection	8057819
34880602	34880625	21	-	27260156	NCIH1373	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.1594546863131903	[323]	[732,506,638,373]	9	hSpCas9	negative selection	8057820
34892921	34892944	21	+	27260156	NCIH1373	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.0928908124767866	[374]	[239,587,370,144]	0	hSpCas9	negative selection	8057821
34887019	34887042	21	-	27260156	PATU8902	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.14030640797114072	[467]	[557,572,776,976]	1	hSpCas9	negative selection	8114816
34887058	34887081	21	+	27260156	PATU8902	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.1120761616806112	[114]	[112,881,127,316]	9	hSpCas9	negative selection	8114817
34880563	34880586	21	+	27260156	PATU8902	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-1.1547281320493639	[1034]	[901,502,455,785]	-7	hSpCas9	negative selection	8114818
34892924	34892947	21	-	27260156	PATU8902	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.042778032264816135	[232]	[336,225,239,494]	0	hSpCas9	negative selection	8179070
34880602	34880625	21	-	27260156	PATU8902	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.21821376278623095	[323]	[360,348,457,358]	-2	hSpCas9	negative selection	8179071
34892921	34892944	21	+	27260156	PATU8902	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.16658957980511535	[374]	[560,441,340,1123]	1	hSpCas9	negative selection	8179072
34887019	34887042	21	-	27260156	PANC1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.4105860630433017	[467]	[586,735,377,475]	6	hSpCas9	negative selection	8236067
34887058	34887081	21	+	27260156	PANC1	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.2854347941024562	[114]	[151,98,153,76]	4	hSpCas9	negative selection	8236068
34880563	34880586	21	+	27260156	PANC1	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.3092587305922916	[1034]	[1114,1334,1170,855]	5	hSpCas9	negative selection	8236069
34892924	34892947	21	-	27260156	PANC1	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.42376514334623094	[232]	[252,337,279,220]	7	hSpCas9	negative selection	8300321
34880602	34880625	21	-	27260156	PANC1	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.20758078459676982	[323]	[300,376,274,335]	3	hSpCas9	negative selection	8300322
34892921	34892944	21	+	27260156	PANC1	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.30635251814055864	[374]	[279,245,293,220]	-5	hSpCas9	negative selection	8300323
34887019	34887042	21	-	27260156	PANC0813	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.8202968228217015	[467]	[961,1163,1136,636]	9	hSpCas9	negative selection	8357318
34887058	34887081	21	+	27260156	PANC0813	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.3506174675551583	[114]	[293,265,307,495]	9	hSpCas9	negative selection	8357319
34880563	34880586	21	+	27260156	PANC0813	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	1.3627734147380919	[1034]	[3671,3369,2943,2594]	9	hSpCas9	negative selection	8357320
34892924	34892947	21	-	27260156	PANC0813	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.6786690124730526	[232]	[505,483,391,378]	9	hSpCas9	negative selection	8421572
34880602	34880625	21	-	27260156	PANC0813	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	1.1359479302296058	[323]	[781,921,937,704]	9	hSpCas9	negative selection	8421573
34892921	34892944	21	+	27260156	PANC0813	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.2806250152745895	[374]	[828,405,481,453]	4	hSpCas9	negative selection	8421574
34887019	34887042	21	-	27260156	RDES	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.3940956947682042	[467]	[661,601,792,783]	6	hSpCas9	negative selection	8478569
34887058	34887081	21	+	27260156	RDES	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.0100629463351192	[114]	[226,191,318,349]	9	hSpCas9	negative selection	8478570
34880563	34880586	21	+	27260156	RDES	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.07104986895669474	[1034]	[996,957,1489,1677]	1	hSpCas9	negative selection	8478571
34892924	34892947	21	-	27260156	RDES	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.1640473309237117	[232]	[237,345,324,290]	2	hSpCas9	negative selection	8542823
34880602	34880625	21	-	27260156	RDES	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.015432439859508817	[323]	[312,299,367,524]	0	hSpCas9	negative selection	8542824
34892921	34892944	21	+	27260156	RDES	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.040678939483490995	[374]	[327,332,500,554]	0	hSpCas9	negative selection	8542825
34887019	34887042	21	-	27260156	PC3	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.009292892536508425	[467]	[228,363,1074,498]	0	hSpCas9	negative selection	8599820
34887058	34887081	21	+	27260156	PC3	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.6163266999548476	[114]	[173,170,181,151]	9	hSpCas9	negative selection	8599821
34880563	34880586	21	+	27260156	PC3	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.28382617740985916	[1034]	[749,1287,2166,1276]	6	hSpCas9	negative selection	8599822
34892924	34892947	21	-	27260156	PC3	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.3209171593398962	[232]	[143,349,661,181]	7	hSpCas9	negative selection	8664074
34880602	34880625	21	-	27260156	PC3	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.2469554766539792	[323]	[145,253,635,225]	-5	hSpCas9	negative selection	8664075
34892921	34892944	21	+	27260156	PC3	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.05983936756238112	[374]	[207,333,700,359]	-1	hSpCas9	negative selection	8664076
34887019	34887042	21	-	27260156	PATU8988T	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.08065956474459908	[467]	[489,421,311,703]	1	hSpCas9	negative selection	8721071
34887058	34887081	21	+	27260156	PATU8988T	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.2728128267903127	[114]	[203,531,184,170]	9	hSpCas9	negative selection	8721072
34880563	34880586	21	+	27260156	PATU8988T	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.012721856455011338	[1034]	[747,1196,834,1298]	0	hSpCas9	negative selection	8721073
34892924	34892947	21	-	27260156	PATU8988T	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.5783636826143436	[232]	[474,310,210,347]	8	hSpCas9	negative selection	8785325
34880602	34880625	21	-	27260156	PATU8988T	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.10905290557203373	[323]	[300,386,410,247]	2	hSpCas9	negative selection	8785326
34892921	34892944	21	+	27260156	PATU8988T	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.08282694616846056	[374]	[326,369,576,245]	1	hSpCas9	negative selection	8785327
34887019	34887042	21	-	27260156	T47D	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.03392573274003446	[467]	[620,501,530,584]	0	hSpCas9	negative selection	8842322
34887058	34887081	21	+	27260156	T47D	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.5841485491345246	[114]	[193,187,222,198]	9	hSpCas9	negative selection	8842323
34880563	34880586	21	+	27260156	T47D	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.27983356546543026	[1034]	[1478,1411,1460,1508]	6	hSpCas9	negative selection	8842324
34892924	34892947	21	-	27260156	T47D	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.09869878269318377	[232]	[320,289,305,243]	2	hSpCas9	negative selection	8906576
34880602	34880625	21	-	27260156	T47D	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.11676709488111203	[323]	[466,384,333,455]	2	hSpCas9	negative selection	8906577
34892921	34892944	21	+	27260156	T47D	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.05024880863665532	[374]	[430,414,481,484]	1	hSpCas9	negative selection	8906578
34887019	34887042	21	-	27260156	SU8686	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.02366039622938768	[467]	[409,393,595,509]	0	hSpCas9	negative selection	8963573
34887058	34887081	21	+	27260156	SU8686	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	1.1542790274440053	[114]	[221,225,172,424]	9	hSpCas9	negative selection	8963574
34880563	34880586	21	+	27260156	SU8686	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	-0.12306773862574061	[1034]	[837,700,1099,1214]	-2	hSpCas9	negative selection	8963575
34892924	34892947	21	-	27260156	SU8686	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.5328812530796887	[232]	[341,253,348,411]	8	hSpCas9	negative selection	9027827
34880602	34880625	21	-	27260156	SU8686	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.14831418696333964	[323]	[351,314,414,344]	2	hSpCas9	negative selection	9027828
34892921	34892944	21	+	27260156	SU8686	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.1387322057986548	[374]	[307,293,336,433]	-2	hSpCas9	negative selection	9027829
34887019	34887042	21	-	27260156	SKES1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.35558374438427337	[467]	[529,571,549,705]	7	hSpCas9	negative selection	9084824
34887058	34887081	21	+	27260156	SKES1	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.37612905623437176	[114]	[137,192,126,140]	7	hSpCas9	negative selection	9084825
34880563	34880586	21	+	27260156	SKES1	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.2231125612786129	[1034]	[1286,1269,1038,1229]	5	hSpCas9	negative selection	9084826
34892924	34892947	21	-	27260156	SKES1	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.21238879493082685	[232]	[286,173,329,272]	4	hSpCas9	negative selection	9149078
34880602	34880625	21	-	27260156	SKES1	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.022657423846977442	[323]	[329,417,308,270]	0	hSpCas9	negative selection	9149079
34892921	34892944	21	+	27260156	SKES1	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	-0.055022635499212824	[374]	[369,427,309,340]	-1	hSpCas9	negative selection	9149080
34887019	34887042	21	-	27260156	TOV112D	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.2361911396519831	[467]	[711,860,353,374]	4	hSpCas9	negative selection	9206075
34887058	34887081	21	+	27260156	TOV112D	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.5848817574433918	[114]	[204,196,217,81]	9	hSpCas9	negative selection	9206076
34880563	34880586	21	+	27260156	TOV112D	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.36044043880006926	[1034]	[1107,1901,1288,1148]	6	hSpCas9	negative selection	9206077
34892924	34892947	21	-	27260156	TOV112D	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	-0.83465553001587	[232]	[101,172,156,99]	-9	hSpCas9	negative selection	9270329
34880602	34880625	21	-	27260156	TOV112D	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.171404821420856	[323]	[240,442,283,497]	3	hSpCas9	negative selection	9270330
34892921	34892944	21	+	27260156	TOV112D	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.034952261565401266	[374]	[450,614,339,199]	0	hSpCas9	negative selection	9270331
34887019	34887042	21	-	27260156	TC71	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.11893376487320773	[467]	[485,574,557,561]	3	hSpCas9	negative selection	9327326
34887058	34887081	21	+	27260156	TC71	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.697070067952158	[114]	[259,146,134,261]	9	hSpCas9	negative selection	9327327
34880563	34880586	21	+	27260156	TC71	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.2420230446546645	[1034]	[1045,1481,1370,1355]	6	hSpCas9	negative selection	9327328
34892924	34892947	21	-	27260156	TC71	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.12217522019280347	[232]	[304,284,216,281]	3	hSpCas9	negative selection	9391580
34880602	34880625	21	-	27260156	TC71	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	-0.04329541043964946	[323]	[428,223,379,309]	-1	hSpCas9	negative selection	9391581
34892921	34892944	21	+	27260156	TC71	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.12085846007084619	[374]	[376,513,453,401]	3	hSpCas9	negative selection	9391582
34887019	34887042	21	-	27260156	TC32	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.20474957569497143	[467]	[492,376,581,614]	3	hSpCas9	negative selection	9448577
34887058	34887081	21	+	27260156	TC32	viability	CGGTGGAAGGCGGCGTGAAGCGG	RUNX1	ENSG00000159216	0.4108428918344387	[114]	[121,59,240,198]	7	hSpCas9	negative selection	9448578
34880563	34880586	21	+	27260156	TC32	viability	CACTTCGACCGACAAACCTGAGG	RUNX1	ENSG00000159216	0.16143345191988323	[1034]	[1193,745,1165,1321]	3	hSpCas9	negative selection	9448579
34892924	34892947	21	-	27260156	TC32	viability	AATCCTTCTAGAGACGTCCACGG	RUNX1	ENSG00000159216	0.11024235860542664	[232]	[231,155,350,243]	2	hSpCas9	negative selection	9512831
34880602	34880625	21	-	27260156	TC32	viability	TACCGCAGCCATGAAGAACCAGG	RUNX1	ENSG00000159216	0.4872717040985832	[323]	[250,411,571,503]	8	hSpCas9	negative selection	9512832
34892921	34892944	21	+	27260156	TC32	viability	ATACCGTGGACGTCTCTAGAAGG	RUNX1	ENSG00000159216	0.03716332932601207	[374]	[304,386,456,282]	0	hSpCas9	negative selection	9512833
34799344	34799367	21	+	27869803	HPAFII	viability after 27 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.058379857375742	[409]	[587,332,NaN]	8	hSpCas9	negative selection	9579162
34834565	34834588	21	-	27869803	HPAFII	viability after 27 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.011364066495091585	[484]	[250,261,NaN]	0	hSpCas9	negative selection	9579163
34859518	34859541	21	+	27869803	HPAFII	viability after 27 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.8174533270006628	[450]	[181,94,NaN]	-5	hSpCas9	negative selection	9579164
34880562	34880585	21	-	27869803	HPAFII	viability after 27 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.9858058968505032	[478]	[741,295,NaN]	7	hSpCas9	negative selection	9579165
34887019	34887042	21	-	27869803	HPAFII	viability after 27 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-2.6521453979793055	[24]	[0,2,NaN]	-8	hSpCas9	negative selection	9579166
35048847	35048870	21	+	27869803	HPAFII	viability after 27 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.2699764146062432	[362]	[178,140,NaN]	-2	hSpCas9	negative selection	9579167
34799344	34799367	21	+	27869803	HPAFII	viability after 15 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.6956581490574927	[409]	[918,585,NaN]	7	hSpCas9	negative selection	9661611
34834565	34834588	21	-	27869803	HPAFII	viability after 15 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.24465827744129254	[484]	[664,299,NaN]	-3	hSpCas9	negative selection	9661612
34859518	34859541	21	+	27869803	HPAFII	viability after 15 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.19560068256629182	[450]	[569,331,NaN]	-2	hSpCas9	negative selection	9661613
34880562	34880585	21	-	27869803	HPAFII	viability after 15 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.709157176920451	[478]	[803,864,NaN]	7	hSpCas9	negative selection	9661614
34887019	34887042	21	-	27869803	HPAFII	viability after 15 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.34764499603790044	[24]	[1,32,NaN]	-4	hSpCas9	negative selection	9661615
35048847	35048870	21	+	27869803	HPAFII	viability after 15 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.2143451317970384	[362]	[318,346,NaN]	-2	hSpCas9	negative selection	9661616
34799344	34799367	21	+	27869803	ASPC1	viability after 36 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.27600090752244455	[1214]	[668,558,362]	2	hSpCas9	negative selection	9744060
34834565	34834588	21	-	27869803	ASPC1	viability after 36 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.35604892601236143	[1018]	[412,252,199]	-4	hSpCas9	negative selection	9744061
34859518	34859541	21	+	27869803	ASPC1	viability after 36 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.4862062041901486	[1402]	[177,174,604]	-5	hSpCas9	negative selection	9744062
34880562	34880585	21	-	27869803	ASPC1	viability after 36 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.6096861639534542	[1185]	[426,1133,369]	6	hSpCas9	negative selection	9744063
34887019	34887042	21	-	27869803	ASPC1	viability after 36 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.38632558775792747	[121]	[27,12,50]	-4	hSpCas9	negative selection	9744064
35048847	35048870	21	+	27869803	ASPC1	viability after 36 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.2590854232588205	[747]	[332,137,198]	-3	hSpCas9	negative selection	9744065
34799344	34799367	21	+	27869803	PATU8988S	viability after 35 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.3703848292372221	[735]	[245,520,NaN]	4	hSpCas9	negative selection	9826509
34834565	34834588	21	-	27869803	PATU8988S	viability after 35 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.4866466391773808	[748]	[501,342,NaN]	5	hSpCas9	negative selection	9826510
34859518	34859541	21	+	27869803	PATU8988S	viability after 35 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-0.22818267134405545	[1053]	[317,406,NaN]	-2	hSpCas9	negative selection	9826511
34880562	34880585	21	-	27869803	PATU8988S	viability after 35 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.4618686318235159	[1160]	[655,631,NaN]	5	hSpCas9	negative selection	9826512
34887019	34887042	21	-	27869803	PATU8988S	viability after 35 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.9516559058946443	[51]	[42,37,NaN]	8	hSpCas9	negative selection	9826513
35048847	35048870	21	+	27869803	PATU8988S	viability after 35 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.37050024785941527	[540]	[362,199,NaN]	4	hSpCas9	negative selection	9826514
34799344	34799367	21	+	27869803	PATU8988S	viability after 31 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	0.45154610859527294	[735]	[249,593,NaN]	5	hSpCas9	negative selection	9908958
34834565	34834588	21	-	27869803	PATU8988S	viability after 31 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	0.39403158860091514	[748]	[468,294,NaN]	5	hSpCas9	negative selection	9908959
34859518	34859541	21	+	27869803	PATU8988S	viability after 31 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	0.17644021679781485	[1053]	[426,535,NaN]	2	hSpCas9	negative selection	9908960
34880562	34880585	21	-	27869803	PATU8988S	viability after 31 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.4922557481129395	[1160]	[615,695,NaN]	6	hSpCas9	negative selection	9908961
34887019	34887042	21	-	27869803	PATU8988S	viability after 31 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.7926773427183633	[51]	[27,45,NaN]	8	hSpCas9	negative selection	9908962
35048847	35048870	21	+	27869803	PATU8988S	viability after 31 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	0.7019833813374332	[540]	[353,346,NaN]	7	hSpCas9	negative selection	9908963
34799344	34799367	21	+	27869803	HPAFII	viability after 35 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.5107319418950638	[409]	[796,359,NaN]	8	hSpCas9	negative selection	9991407
34834565	34834588	21	-	27869803	HPAFII	viability after 35 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.785314481917064	[484]	[125,160,NaN]	-4	hSpCas9	negative selection	9991408
34859518	34859541	21	+	27869803	HPAFII	viability after 35 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-1.63076858467873	[450]	[116,24,NaN]	-7	hSpCas9	negative selection	9991409
34880562	34880585	21	-	27869803	HPAFII	viability after 35 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.9061487086984219	[478]	[627,258,NaN]	6	hSpCas9	negative selection	9991410
34887019	34887042	21	-	27869803	HPAFII	viability after 35 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-2.392095779022111	[24]	[0,3,NaN]	-8	hSpCas9	negative selection	9991411
35048847	35048870	21	+	27869803	HPAFII	viability after 35 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.1351334134147087	[362]	[132,205,NaN]	-1	hSpCas9	negative selection	9991412
34799344	34799367	21	+	27869803	HPAFII	viability after 31 days	GCTGGCACGTCCAGGTGAAATGG	RUNX1	ENSG00000159216	1.3030212412945856	[409]	[740,378,NaN]	8	hSpCas9	negative selection	10073856
34834565	34834588	21	-	27869803	HPAFII	viability after 31 days	CTAGATGATCAGACCAAGCCCGG	RUNX1	ENSG00000159216	-0.5628370741375002	[484]	[178,189,NaN]	-4	hSpCas9	negative selection	10073857
34859518	34859541	21	+	27869803	HPAFII	viability after 31 days	TGGTAGGTGGCGACTTGCGGTGG	RUNX1	ENSG00000159216	-1.2169415477129215	[450]	[83,135,NaN]	-6	hSpCas9	negative selection	10073858
34880562	34880585	21	-	27869803	HPAFII	viability after 31 days	CTCAGGTTTGTCGGTCGAAGTGG	RUNX1	ENSG00000159216	0.5180969209813917	[478]	[495,263,NaN]	4	hSpCas9	negative selection	10073859
34887019	34887042	21	-	27869803	HPAFII	viability after 31 days	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-2.526140078020261	[24]	[0,3,NaN]	-8	hSpCas9	negative selection	10073860
35048847	35048870	21	+	27869803	HPAFII	viability after 31 days	ATGAAGCACTGTGGGTACGAAGG	RUNX1	ENSG00000159216	-0.39492860994488405	[362]	[119,192,NaN]	-3	hSpCas9	negative selection	10073861
34887061	34887084	21	+	28162770	P31FUJ	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.1791754951154072	[117]	[156]	1	hSpCas9	negative selection	10228997
34886934	34886957	21	-	28162770	P31FUJ	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-0.9568287428730866	[184]	[111]	-6	hSpCas9	negative selection	10228998
34887031	34887054	21	-	28162770	P31FUJ	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-0.6573000329422887	[101]	[75]	-5	hSpCas9	negative selection	10228999
34886881	34886904	21	+	28162770	P31FUJ	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-2.2994732440596666	[154]	[36]	-8	hSpCas9	negative selection	10229000
34859495	34859518	21	-	28162770	P31FUJ	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-0.3460128148623691	[52]	[48]	-3	hSpCas9	negative selection	10229001
34834564	34834587	21	-	28162770	P31FUJ	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-0.4624717914497524	[264]	[225]	-4	hSpCas9	negative selection	10229002
34887019	34887042	21	-	28162770	P31FUJ	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.1457094188393513	[44]	[116]	9	hSpCas9	negative selection	10229003
34886973	34886996	21	-	28162770	P31FUJ	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	0.5320424223272642	[368]	[626]	6	hSpCas9	negative selection	10229004
34886956	34886979	21	-	28162770	P31FUJ	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-0.6027518141646846	[251]	[194]	-5	hSpCas9	negative selection	10229005
34886947	34886970	21	+	28162770	P31FUJ	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-1.3424266955888768	[40]	[18]	-7	hSpCas9	negative selection	10229006
34887061	34887084	21	+	28162770	TF1	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10398363
34886934	34886957	21	-	28162770	TF1	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10398364
34887031	34887054	21	-	28162770	TF1	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10398365
34886881	34886904	21	+	28162770	TF1	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10398366
34859495	34859518	21	-	28162770	TF1	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10398367
34834564	34834587	21	-	28162770	TF1	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10398368
34887019	34887042	21	-	28162770	TF1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10398369
34886973	34886996	21	-	28162770	TF1	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10398370
34886956	34886979	21	-	28162770	TF1	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10398371
34886947	34886970	21	+	28162770	TF1	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10398372
34887061	34887084	21	+	28162770	SKM1	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.3439544012173614	[27]	[38]	-3	hSpCas9	negative selection	10567729
34886934	34886957	21	-	28162770	SKM1	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-2.6293566200796095	[20]	[5]	-9	hSpCas9	negative selection	10567730
34887031	34887054	21	-	28162770	SKM1	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.6964708159381465	[32]	[17]	-8	hSpCas9	negative selection	10567731
34886881	34886904	21	+	28162770	SKM1	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-5.46585788779673	[49]	[1]	-9	hSpCas9	negative selection	10567732
34859495	34859518	21	-	28162770	SKM1	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.6293566200796095	[13]	[3]	-9	hSpCas9	negative selection	10567733
34834564	34834587	21	-	28162770	SKM1	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.646430133438551	[84]	[47]	-8	hSpCas9	negative selection	10567734
34887019	34887042	21	-	28162770	SKM1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.6560455987826386	[13]	[38]	6	hSpCas9	negative selection	10567735
34886973	34886996	21	-	28162770	SKM1	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.1756386526367057	[91]	[71]	-7	hSpCas9	negative selection	10567736
34886956	34886979	21	-	28162770	SKM1	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-4.880895387075574	[49]	[2]	-9	hSpCas9	negative selection	10567737
34886947	34886970	21	+	28162770	SKM1	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.13012399338433722	[12]	[20]	-1	hSpCas9	negative selection	10567738
34887061	34887084	21	+	28162770	SKM1	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.3439544012173614	[27]	[38]	-3	hSpCas9	negative selection	10737095
34886934	34886957	21	-	28162770	SKM1	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-2.6293566200796095	[20]	[5]	-9	hSpCas9	negative selection	10737096
34887031	34887054	21	-	28162770	SKM1	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.6964708159381465	[32]	[17]	-8	hSpCas9	negative selection	10737097
34886881	34886904	21	+	28162770	SKM1	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-5.46585788779673	[49]	[1]	-9	hSpCas9	negative selection	10737098
34859495	34859518	21	-	28162770	SKM1	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.6293566200796095	[13]	[3]	-9	hSpCas9	negative selection	10737099
34834564	34834587	21	-	28162770	SKM1	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.646430133438551	[84]	[47]	-8	hSpCas9	negative selection	10737100
34887019	34887042	21	-	28162770	SKM1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.6560455987826386	[13]	[38]	6	hSpCas9	negative selection	10737101
34886973	34886996	21	-	28162770	SKM1	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.1756386526367057	[91]	[71]	-7	hSpCas9	negative selection	10737102
34886956	34886979	21	-	28162770	SKM1	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-4.880895387075574	[49]	[2]	-9	hSpCas9	negative selection	10737103
34886947	34886970	21	+	28162770	SKM1	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.13012399338433722	[12]	[20]	-1	hSpCas9	negative selection	10737104
34887061	34887084	21	+	28162770	PL21	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.3404287668733825	[95]	[32]	-2	hSpCas9	negative selection	10906461
34886934	34886957	21	-	28162770	PL21	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-3.8766759825615114	[134]	[3]	-9	hSpCas9	negative selection	10906462
34887031	34887054	21	-	28162770	PL21	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.085262604372928	[77]	[15]	-6	hSpCas9	negative selection	10906463
34886881	34886904	21	+	28162770	PL21	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-1.4055814463986334	[139]	[22]	-7	hSpCas9	negative selection	10906464
34859495	34859518	21	-	28162770	PL21	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-4.929143402455647	[69]	[0]	-9	hSpCas9	negative selection	10906465
34834564	34834587	21	-	28162770	PL21	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.6830467205279298	[331]	[44]	-8	hSpCas9	negative selection	10906466
34887019	34887042	21	-	28162770	PL21	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.4145702296258882	[48]	[15]	-3	hSpCas9	negative selection	10906467
34886973	34886996	21	-	28162770	PL21	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-0.9594062411729929	[276]	[61]	-6	hSpCas9	negative selection	10906468
34886956	34886979	21	-	28162770	PL21	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-1.832875442738643	[220]	[26]	-8	hSpCas9	negative selection	10906469
34886947	34886970	21	+	28162770	PL21	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	1.431465160595776	[22]	[26]	9	hSpCas9	negative selection	10906470
34887061	34887084	21	+	28162770	P31FUJ	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.1791754951154072	[117]	[156]	1	hSpCas9	negative selection	11075827
34886934	34886957	21	-	28162770	P31FUJ	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-0.9568287428730866	[184]	[111]	-6	hSpCas9	negative selection	11075828
34887031	34887054	21	-	28162770	P31FUJ	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-0.6573000329422887	[101]	[75]	-5	hSpCas9	negative selection	11075829
34886881	34886904	21	+	28162770	P31FUJ	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-2.2994732440596666	[154]	[36]	-8	hSpCas9	negative selection	11075830
34859495	34859518	21	-	28162770	P31FUJ	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-0.3460128148623691	[52]	[48]	-3	hSpCas9	negative selection	11075831
34834564	34834587	21	-	28162770	P31FUJ	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-0.4624717914497524	[264]	[225]	-4	hSpCas9	negative selection	11075832
34887019	34887042	21	-	28162770	P31FUJ	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.1457094188393513	[44]	[116]	9	hSpCas9	negative selection	11075833
34886973	34886996	21	-	28162770	P31FUJ	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	0.5320424223272642	[368]	[626]	6	hSpCas9	negative selection	11075834
34886956	34886979	21	-	28162770	P31FUJ	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-0.6027518141646846	[251]	[194]	-5	hSpCas9	negative selection	11075835
34886947	34886970	21	+	28162770	P31FUJ	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-1.3424266955888768	[40]	[18]	-7	hSpCas9	negative selection	11075836
34887061	34887084	21	+	28162770	OCIAML5	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-2.0296047564161848	[94]	[41]	-8	hSpCas9	negative selection	11245193
34886934	34886957	21	-	28162770	OCIAML5	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-2.6916018986707506	[67]	[18]	-8	hSpCas9	negative selection	11245194
34887031	34887054	21	-	28162770	OCIAML5	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.1739946657513594	[69]	[55]	-6	hSpCas9	negative selection	11245195
34886881	34886904	21	+	28162770	OCIAML5	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-1.8927085553613427	[71]	[34]	-7	hSpCas9	negative selection	11245196
34859495	34859518	21	-	28162770	OCIAML5	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.7906660261998537	[22]	[5]	-8	hSpCas9	negative selection	11245197
34834564	34834587	21	-	28162770	OCIAML5	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-0.8413401642709385	[133]	[134]	-5	hSpCas9	negative selection	11245198
34887019	34887042	21	-	28162770	OCIAML5	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.16423524146510338	[43]	[88]	1	hSpCas9	negative selection	11245199
34886973	34886996	21	-	28162770	OCIAML5	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.7897006899036234	[248]	[129]	-7	hSpCas9	negative selection	11245200
34886956	34886979	21	-	28162770	OCIAML5	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-1.2105205417764733	[149]	[116]	-6	hSpCas9	negative selection	11245201
34886947	34886970	21	+	28162770	OCIAML5	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.027153277422088395	[34]	[61]	0	hSpCas9	negative selection	11245202
34887061	34887084	21	+	28162770	EOL1	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.14948238746943576	[242]	[141]	1	hSpCas9	negative selection	11414559
34886934	34886957	21	-	28162770	EOL1	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-2.830339730592934	[161]	[11]	-9	hSpCas9	negative selection	11414560
34887031	34887054	21	-	28162770	EOL1	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-2.3897671392069526	[188]	[18]	-8	hSpCas9	negative selection	11414561
34886881	34886904	21	+	28162770	EOL1	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-6.10335822499935	[260]	[1]	-9	hSpCas9	negative selection	11414562
34859495	34859518	21	-	28162770	EOL1	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.4601160786647904	[93]	[8]	-8	hSpCas9	negative selection	11414563
34834564	34834587	21	-	28162770	EOL1	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-0.3903825971920081	[616]	[247]	-3	hSpCas9	negative selection	11414564
34887019	34887042	21	-	28162770	EOL1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.38665391672376925	[66]	[26]	-3	hSpCas9	negative selection	11414565
34886973	34886996	21	-	28162770	EOL1	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.1324831734658445	[386]	[92]	-6	hSpCas9	negative selection	11414566
34886956	34886979	21	-	28162770	EOL1	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-3.3750125102883732	[255]	[12]	-9	hSpCas9	negative selection	11414567
34886947	34886970	21	+	28162770	EOL1	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-3.3608544472917137	[38]	[1]	-9	hSpCas9	negative selection	11414568
34887061	34887084	21	+	28162770	MOLM13	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.009269829642062577	[173]	[124]	0	hSpCas9	negative selection	11583925
34886934	34886957	21	-	28162770	MOLM13	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-2.4602176999736356	[136]	[17]	-8	hSpCas9	negative selection	11583926
34887031	34887054	21	-	28162770	MOLM13	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.305339756608399	[187]	[54]	-6	hSpCas9	negative selection	11583927
34886881	34886904	21	+	28162770	MOLM13	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-1.8864601910351608	[224]	[43]	-7	hSpCas9	negative selection	11583928
34859495	34859518	21	-	28162770	MOLM13	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-3.086699470133059	[93]	[7]	-8	hSpCas9	negative selection	11583929
34834564	34834587	21	-	28162770	MOLM13	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-2.1962998103271527	[392]	[61]	-7	hSpCas9	negative selection	11583930
34887019	34887042	21	-	28162770	MOLM13	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.6925752906486673	[75]	[33]	-4	hSpCas9	negative selection	11583931
34886973	34886996	21	-	28162770	MOLM13	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-2.0514847775490006	[429]	[74]	-7	hSpCas9	negative selection	11583932
34886956	34886979	21	-	28162770	MOLM13	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-2.185552857059344	[301]	[47]	-7	hSpCas9	negative selection	11583933
34886947	34886970	21	+	28162770	MOLM13	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-1.117073119176577	[50]	[16]	-5	hSpCas9	negative selection	11583934
34887061	34887084	21	+	28162770	HEL	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-1.7686874137261077	[132]	[24]	-7	hSpCas9	negative selection	11753291
34886934	34886957	21	-	28162770	HEL	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-6.177440130414831	[112]	[0]	-9	hSpCas9	negative selection	11753292
34887031	34887054	21	-	28162770	HEL	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-6.434076765050474	[134]	[0]	-9	hSpCas9	negative selection	11753293
34886881	34886904	21	+	28162770	HEL	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-4.630279662406059	[231]	[5]	-9	hSpCas9	negative selection	11753294
34859495	34859518	21	-	28162770	HEL	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-4.177440130414831	[112]	[3]	-9	hSpCas9	negative selection	11753295
34834564	34834587	21	-	28162770	HEL	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-3.2919349201216996	[366]	[23]	-9	hSpCas9	negative selection	11753296
34887019	34887042	21	-	28162770	HEL	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.24137626961859	[34]	[52]	9	hSpCas9	negative selection	11753297
34886973	34886996	21	-	28162770	HEL	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-4.597575497333353	[377]	[9]	-9	hSpCas9	negative selection	11753298
34886956	34886979	21	-	28162770	HEL	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-3.521007594512831	[232]	[12]	-9	hSpCas9	negative selection	11753299
34886947	34886970	21	+	28162770	HEL	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-4.749578590778404	[41]	[0]	-9	hSpCas9	negative selection	11753300
34887061	34887084	21	+	28162770	MV411	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-1.256793677825524	[138]	[48]	-7	hSpCas9	negative selection	11922657
34886934	34886957	21	-	28162770	MV411	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-4.043239610120148	[136]	[6]	-9	hSpCas9	negative selection	11922658
34887031	34887054	21	-	28162770	MV411	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.582637447774912	[95]	[26]	-7	hSpCas9	negative selection	11922659
34886881	34886904	21	+	28162770	MV411	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-6.850594532177752	[136]	[0]	-9	hSpCas9	negative selection	11922660
34859495	34859518	21	-	28162770	MV411	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-1.8350246094091975	[71]	[16]	-8	hSpCas9	negative selection	11922661
34834564	34834587	21	-	28162770	MV411	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	0.26581608009762975	[233]	[236]	2	hSpCas9	negative selection	11922662
34887019	34887042	21	-	28162770	MV411	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.35295499050798673	[46]	[30]	-3	hSpCas9	negative selection	11922663
34886973	34886996	21	-	28162770	MV411	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.3650056863604876	[317]	[103]	-7	hSpCas9	negative selection	11922664
34886956	34886979	21	-	28162770	MV411	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-1.7238034562358011	[148]	[37]	-8	hSpCas9	negative selection	11922665
34886947	34886970	21	+	28162770	MV411	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	0.4467463590061822	[26]	[30]	4	hSpCas9	negative selection	11922666
34887061	34887084	21	+	28162770	MONOMAC1	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.1051143576185144	[75]	[80]	-1	hSpCas9	negative selection	12092023
34886934	34886957	21	-	28162770	MONOMAC1	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-0.39295705703481054	[62]	[54]	-3	hSpCas9	negative selection	12092024
34887031	34887054	21	-	28162770	MONOMAC1	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-0.2536203754259212	[51]	[49]	-2	hSpCas9	negative selection	12092025
34886881	34886904	21	+	28162770	MONOMAC1	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-1.363686716469005	[109]	[48]	-8	hSpCas9	negative selection	12092026
34859495	34859518	21	-	28162770	MONOMAC1	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-0.16728950366550177	[47]	[48]	-1	hSpCas9	negative selection	12092027
34834564	34834587	21	-	28162770	MONOMAC1	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-0.8858351587652498	[215]	[133]	-6	hSpCas9	negative selection	12092028
34887019	34887042	21	-	28162770	MONOMAC1	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	1.2623947715777435	[27]	[76]	9	hSpCas9	negative selection	12092029
34886973	34886996	21	-	28162770	MONOMAC1	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.339994800901597	[158]	[71]	-7	hSpCas9	negative selection	12092030
34886956	34886979	21	-	28162770	MONOMAC1	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	0.03742840657746918	[118]	[139]	0	hSpCas9	negative selection	12092031
34886947	34886970	21	+	28162770	MONOMAC1	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-1.419429268396002	[13]	[5]	-8	hSpCas9	negative selection	12092032
34887061	34887084	21	+	28162770	OCIAML2	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	0.07126395358710891	[16]	[98]	0	hSpCas9	negative selection	12261389
34886934	34886957	21	-	28162770	OCIAML2	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-1.108059745857453	[13]	[35]	-6	hSpCas9	negative selection	12261390
34887031	34887054	21	-	28162770	OCIAML2	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	-1.1169928706274606	[35]	[91]	-6	hSpCas9	negative selection	12261391
34886881	34886904	21	+	28162770	OCIAML2	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-3.1768986221854507	[30]	[18]	-9	hSpCas9	negative selection	12261392
34859495	34859518	21	-	28162770	OCIAML2	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	-2.608133348992096	[10]	[9]	-8	hSpCas9	negative selection	12261393
34834564	34834587	21	-	28162770	OCIAML2	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	-1.4814365801987441	[66]	[132]	-7	hSpCas9	negative selection	12261394
34887019	34887042	21	-	28162770	OCIAML2	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	-0.085965975006836	[8]	[46]	0	hSpCas9	negative selection	12261395
34886973	34886996	21	-	28162770	OCIAML2	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-0.30916640254804484	[37]	[169]	-3	hSpCas9	negative selection	12261396
34886956	34886979	21	-	28162770	OCIAML2	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-3.219091058246197	[41]	[24]	-9	hSpCas9	negative selection	12261397
34886947	34886970	21	+	28162770	OCIAML2	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	0.06542307499804867	[4]	[28]	0	hSpCas9	negative selection	12261398
34887061	34887084	21	+	28162770	OCIAML3	viability	TGGAAGGCGGCGTGAAGCGGCGG	RUNX1	ENSG00000159216	-0.4835836506305126	[43]	[94]	-4	hSpCas9	negative selection	12430755
34886934	34886957	21	-	28162770	OCIAML3	viability	GAGGTGCTGGCCGACCACCCGGG	RUNX1	ENSG00000159216	-1.594007640324163	[35]	[35]	-8	hSpCas9	negative selection	12430756
34887031	34887054	21	-	28162770	OCIAML3	viability	GAGCCCAGGCAAGATGAGCGAGG	RUNX1	ENSG00000159216	0.6790108540822527	[17]	[86]	6	hSpCas9	negative selection	12430757
34886881	34886904	21	+	28162770	OCIAML3	viability	GCGTAGGCAGCACGGAGCAGAGG	RUNX1	ENSG00000159216	-0.3579402820906388	[44]	[105]	-3	hSpCas9	negative selection	12430758
34859495	34859518	21	-	28162770	OCIAML3	viability	CAGAGCCATCAAAATCACAGTGG	RUNX1	ENSG00000159216	1.6283847810122847	[11]	[111]	9	hSpCas9	negative selection	12430759
34834564	34834587	21	-	28162770	OCIAML3	viability	TAGATGATCAGACCAAGCCCGGG	RUNX1	ENSG00000159216	0.11343886692198812	[78]	[257]	1	hSpCas9	negative selection	12430760
34887019	34887042	21	-	28162770	OCIAML3	viability	GATGAGCGAGGCGTTGCCGCTGG	RUNX1	ENSG00000159216	0.7752261693415561	[11]	[61]	7	hSpCas9	negative selection	12430761
34886973	34886996	21	-	28162770	OCIAML3	viability	CTGGCCGGCAAGCTGAGGAGCGG	RUNX1	ENSG00000159216	-1.0288083944244368	[97]	[144]	-6	hSpCas9	negative selection	12430762
34886956	34886979	21	-	28162770	OCIAML3	viability	GAGCGGCGACCGCAGCATGGTGG	RUNX1	ENSG00000159216	-0.912183600350418	[47]	[76]	-6	hSpCas9	negative selection	12430763
34886947	34886970	21	+	28162770	OCIAML3	viability	CCAGCACCTCCACCATGCTGCGG	RUNX1	ENSG00000159216	-0.9159357352115256	[9]	[15]	-6	hSpCas9	negative selection	12430764