Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6262
• Symbol: RYR2
• Description: ryanodine receptor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/RYR2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
237388162	237388185	1	+	26472758	Jiyoye	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.29669252448410194	[157]	[96]	-2	hSpCas9	negative selection	141533
237548546	237548569	1	+	26472758	Jiyoye	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.5116878557687212	[241]	[127]	-4	hSpCas9	negative selection	141534
237550565	237550588	1	-	26472758	Jiyoye	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.1562815385442916	[212]	[178]	1	hSpCas9	negative selection	141535
237639155	237639178	1	-	26472758	Jiyoye	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-1.5257104226355898	[83]	[21]	-7	hSpCas9	negative selection	141536
237707004	237707027	1	+	26472758	Jiyoye	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	-0.191462056112359	[52]	[34]	-1	hSpCas9	negative selection	141537
237783847	237783870	1	+	26472758	Jiyoye	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.4859094145776145	[116]	[62]	-3	hSpCas9	negative selection	141538
237784131	237784154	1	+	26472758	Jiyoye	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.17271012786885048	[79]	[67]	1	hSpCas9	negative selection	141539
237330946	237330969	1	+	26472758	Jiyoye	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.293518599710306	[65]	[60]	2	hSpCas9	negative selection	141540
237492986	237493009	1	-	26472758	Jiyoye	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.2714573716483131	[322]	[293]	2	hSpCas9	negative selection	141541
237496683	237496706	1	+	26472758	Jiyoye	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.1366484244217963	[120]	[82]	-1	hSpCas9	negative selection	141542
237388162	237388185	1	+	26472758	KBM7	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.8609093670934519	[518,487]	[577,298]	8	hSpCas9	negative selection	332651
237548546	237548569	1	+	26472758	KBM7	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.2829269343135653	[867,778]	[474,466]	3	hSpCas9	negative selection	332652
237550565	237550588	1	-	26472758	KBM7	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.5255040872129192	[809,947]	[770,451]	6	hSpCas9	negative selection	332653
237639155	237639178	1	-	26472758	KBM7	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-0.3242955453588814	[96,55]	[35,20]	-3	hSpCas9	negative selection	332654
237707004	237707027	1	+	26472758	KBM7	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.36783384035697964	[184,110]	[107,69]	4	hSpCas9	negative selection	332655
237783847	237783870	1	+	26472758	KBM7	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.4720094972301563	[729,297]	[502,160]	5	hSpCas9	negative selection	332656
237784131	237784154	1	+	26472758	KBM7	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.4594753740869717	[315,475]	[251,271]	5	hSpCas9	negative selection	332657
237330946	237330969	1	+	26472758	KBM7	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.31993757273324885	[349,245]	[76,140]	-3	hSpCas9	negative selection	332658
237492986	237493009	1	-	26472758	KBM7	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.9045026760654591	[1140,1007]	[890,991]	8	hSpCas9	negative selection	332659
237496683	237496706	1	+	26472758	KBM7	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.400464509450306	[702,845]	[263,293]	-4	hSpCas9	negative selection	332660
237388162	237388185	1	+	26472758	Raji	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.328715579433074	[275]	[50]	-3	hSpCas9	negative selection	523769
237548546	237548569	1	+	26472758	Raji	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.4213349095381287	[398]	[123]	4	hSpCas9	negative selection	523770
237550565	237550588	1	-	26472758	Raji	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.7308201839093913	[295]	[113]	6	hSpCas9	negative selection	523771
237639155	237639178	1	-	26472758	Raji	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	0.10738353537359946	[83]	[20]	1	hSpCas9	negative selection	523772
237707004	237707027	1	+	26472758	Raji	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	1.8381969025582103	[46]	[38]	9	hSpCas9	negative selection	523773
237783847	237783870	1	+	26472758	Raji	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.6895310204877017	[170]	[63]	6	hSpCas9	negative selection	523774
237784131	237784154	1	+	26472758	Raji	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.5694185141896126	[150]	[51]	5	hSpCas9	negative selection	523775
237330946	237330969	1	+	26472758	Raji	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.4786996572231255	[200]	[64]	4	hSpCas9	negative selection	523776
237492986	237493009	1	-	26472758	Raji	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.6038851352813397	[722]	[254]	6	hSpCas9	negative selection	523777
237496683	237496706	1	+	26472758	Raji	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.7133504164852045	[324]	[45]	-5	hSpCas9	negative selection	523778
237388162	237388185	1	+	26472758	K562	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.3314415659474569	[394]	[264]	-2	hSpCas9	negative selection	714887
237548546	237548569	1	+	26472758	K562	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.7565306629799216	[527]	[752]	6	hSpCas9	negative selection	714888
237550565	237550588	1	-	26472758	K562	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.6398418456320963	[684]	[900]	5	hSpCas9	negative selection	714889
237639155	237639178	1	-	26472758	K562	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-0.407657968913246	[109]	[69]	-3	hSpCas9	negative selection	714890
237707004	237707027	1	+	26472758	K562	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	1.3854310371935206	[111]	[246]	9	hSpCas9	negative selection	714891
237783847	237783870	1	+	26472758	K562	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.502309830224281	[280]	[335]	4	hSpCas9	negative selection	714892
237784131	237784154	1	+	26472758	K562	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-1.217259496731186	[481]	[174]	-6	hSpCas9	negative selection	714893
237330946	237330969	1	+	26472758	K562	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.1096219496277363	[212]	[193]	0	hSpCas9	negative selection	714894
237492986	237493009	1	-	26472758	K562	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.3679185700628549	[1006]	[1096]	3	hSpCas9	negative selection	714895
237496683	237496706	1	+	26472758	K562	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-1.3237924087653847	[684]	[230]	-6	hSpCas9	negative selection	714896
237042510	237042533	1	+	26627737	DLD1	viability	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.010243319168487613	[418]	[196,117,81]	0	hSpCas9	negative selection	769871
237270548	237270571	1	+	26627737	DLD1	viability	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.01934836579598466	[497]	[168,107,177]	0	hSpCas9	negative selection	769874
237330924	237330947	1	-	26627737	DLD1	viability	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.8489933245641109	[872]	[136,153,161]	-7	hSpCas9	negative selection	769877
237369590	237369613	1	-	26627737	DLD1	viability	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.6380381134220302	[561]	[124,276,398]	6	hSpCas9	negative selection	769879
237374728	237374751	1	-	26627737	DLD1	viability	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.11093447599548395	[546]	[112,222,214]	1	hSpCas9	negative selection	769880
237377352	237377375	1	+	26627737	DLD1	viability	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	769881
237042510	237042533	1	+	26627737	GBM cells	viability after 5 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.03306770168566353	[144]	[74,76]	0	hSpCas9	negative selection	852186
237270548	237270571	1	+	26627737	GBM cells	viability after 5 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.6931652096691093	[157]	[133,139]	8	hSpCas9	negative selection	852189
237330924	237330947	1	-	26627737	GBM cells	viability after 5 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.02768804735057817	[478]	[298,204]	0	hSpCas9	negative selection	852192
237369590	237369613	1	-	26627737	GBM cells	viability after 5 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.26913752681382896	[563]	[317,410]	4	hSpCas9	negative selection	852194
237374728	237374751	1	-	26627737	GBM cells	viability after 5 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.1583609304660633	[333]	[149,170]	-2	hSpCas9	negative selection	852195
237377352	237377375	1	+	26627737	GBM cells	viability after 5 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	852196
237042510	237042533	1	+	26627737	GBM cells	viability after 13 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.39537347853031096	[144]	[92,111]	5	hSpCas9	negative selection	934501
237270548	237270571	1	+	26627737	GBM cells	viability after 13 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.25230688216405234	[157]	[116,89]	3	hSpCas9	negative selection	934504
237330924	237330947	1	-	26627737	GBM cells	viability after 13 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.30597203535721396	[478]	[360,288]	4	hSpCas9	negative selection	934507
237369590	237369613	1	-	26627737	GBM cells	viability after 13 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.17343473030192103	[563]	[418,284]	2	hSpCas9	negative selection	934509
237374728	237374751	1	-	26627737	GBM cells	viability after 13 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.06752844272845704	[333]	[206,175]	0	hSpCas9	negative selection	934510
237377352	237377375	1	+	26627737	GBM cells	viability after 13 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	934511
237042510	237042533	1	+	26627737	GBM cells	viability after 21 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.7260174832814961	[144]	[134,125]	7	hSpCas9	negative selection	1016816
237270548	237270571	1	+	26627737	GBM cells	viability after 21 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.4790621497191978	[157]	[127,111]	5	hSpCas9	negative selection	1016819
237330924	237330947	1	-	26627737	GBM cells	viability after 21 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.0800918192868757	[478]	[241,249]	0	hSpCas9	negative selection	1016822
237369590	237369613	1	-	26627737	GBM cells	viability after 21 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.7524682784234722	[563]	[534,498]	7	hSpCas9	negative selection	1016824
237374728	237374751	1	-	26627737	GBM cells	viability after 21 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.7364636577783119	[333]	[110,106]	-6	hSpCas9	negative selection	1016825
237377352	237377375	1	+	26627737	GBM cells	viability after 21 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1016826
237042510	237042533	1	+	26627737	RPE1	viability after 9 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.1736750996607916	[787]	[78,398]	-1	hSpCas9	negative selection	1099131
237270548	237270571	1	+	26627737	RPE1	viability after 9 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.8179766991592429	[466]	[162,379]	5	hSpCas9	negative selection	1099134
237330924	237330947	1	-	26627737	RPE1	viability after 9 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.3123769797023718	[1345]	[358,313]	-2	hSpCas9	negative selection	1099137
237369590	237369613	1	-	26627737	RPE1	viability after 9 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	-0.06149707305744845	[1847]	[353,812]	0	hSpCas9	negative selection	1099139
237374728	237374751	1	-	26627737	RPE1	viability after 9 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.7060312273136822	[352]	[360,359]	8	hSpCas9	negative selection	1099140
237377352	237377375	1	+	26627737	RPE1	viability after 9 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1099141
237042510	237042533	1	+	26627737	RPE1	viability after 12 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.45808361849260143	[787]	[123,185]	-3	hSpCas9	negative selection	1181446
237270548	237270571	1	+	26627737	RPE1	viability after 12 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.7530541560397886	[466]	[192,230]	5	hSpCas9	negative selection	1181449
237330924	237330947	1	-	26627737	RPE1	viability after 12 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.23571947095025347	[1345]	[344,266]	-2	hSpCas9	negative selection	1181452
237369590	237369613	1	-	26627737	RPE1	viability after 12 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.44108946037385066	[1847]	[454,905]	3	hSpCas9	negative selection	1181454
237374728	237374751	1	-	26627737	RPE1	viability after 12 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.543648168088409	[352]	[156,402]	8	hSpCas9	negative selection	1181455
237377352	237377375	1	+	26627737	RPE1	viability after 12 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1181456
237042510	237042533	1	+	26627737	RPE1	viability after 15 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.6022524178657445	[787]	[127,164]	-4	hSpCas9	negative selection	1263761
237270548	237270571	1	+	26627737	RPE1	viability after 15 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.6373694149610107	[466]	[149,258]	4	hSpCas9	negative selection	1263764
237330924	237330947	1	-	26627737	RPE1	viability after 15 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.05572759555719875	[1345]	[437,354]	0	hSpCas9	negative selection	1263767
237369590	237369613	1	-	26627737	RPE1	viability after 15 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.1801697803480109	[1847]	[406,770]	1	hSpCas9	negative selection	1263769
237374728	237374751	1	-	26627737	RPE1	viability after 15 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.5528810916640572	[352]	[265,318]	8	hSpCas9	negative selection	1263770
237377352	237377375	1	+	26627737	RPE1	viability after 15 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1263771
237042510	237042533	1	+	26627737	RPE1	viability after 18 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.14397086729900085	[787]	[132,255]	-1	hSpCas9	negative selection	1346076
237270548	237270571	1	+	26627737	RPE1	viability after 18 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.8475819354176389	[466]	[103,357]	5	hSpCas9	negative selection	1346079
237330924	237330947	1	-	26627737	RPE1	viability after 18 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.25643964576569755	[1345]	[262,347]	-2	hSpCas9	negative selection	1346082
237369590	237369613	1	-	26627737	RPE1	viability after 18 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.3240663483653208	[1847]	[487,769]	2	hSpCas9	negative selection	1346084
237374728	237374751	1	-	26627737	RPE1	viability after 18 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.4974283130575656	[352]	[165,378]	7	hSpCas9	negative selection	1346085
237377352	237377375	1	+	26627737	RPE1	viability after 18 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1346086
237042510	237042533	1	+	26627737	HeLa	viability after 8 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.9162505257968343	[703]	[244,50,205]	-7	hSpCas9	negative selection	1428391
237270548	237270571	1	+	26627737	HeLa	viability after 8 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.22452588182552657	[181]	[96,124,58]	2	hSpCas9	negative selection	1428394
237330924	237330947	1	-	26627737	HeLa	viability after 8 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.20191690774348126	[737]	[603,278,282]	2	hSpCas9	negative selection	1428397
237369590	237369613	1	-	26627737	HeLa	viability after 8 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.1412637893861568	[674]	[417,346,233]	1	hSpCas9	negative selection	1428399
237374728	237374751	1	-	26627737	HeLa	viability after 8 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.22652638960705568	[523]	[292,318,198]	2	hSpCas9	negative selection	1428400
237377352	237377375	1	+	26627737	HeLa	viability after 8 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1428401
237042510	237042533	1	+	26627737	HeLa	viability after 12 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.993312801085286	[703]	[313,16,125]	-7	hSpCas9	negative selection	1510706
237270548	237270571	1	+	26627737	HeLa	viability after 12 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.9525272729682853	[181]	[152,153,128]	7	hSpCas9	negative selection	1510709
237330924	237330947	1	-	26627737	HeLa	viability after 12 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.3637967321584745	[737]	[531,273,387]	3	hSpCas9	negative selection	1510712
237369590	237369613	1	-	26627737	HeLa	viability after 12 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.05402251503880018	[674]	[332,308,225]	0	hSpCas9	negative selection	1510714
237374728	237374751	1	-	26627737	HeLa	viability after 12 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.5401312559271414	[523]	[360,380,196]	4	hSpCas9	negative selection	1510715
237377352	237377375	1	+	26627737	HeLa	viability after 12 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1510716
237042510	237042533	1	+	26627737	HeLa	viability after 15 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.5941713915861333	[703]	[121,299,144]	-5	hSpCas9	negative selection	1593021
237270548	237270571	1	+	26627737	HeLa	viability after 15 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.6129922325517699	[181]	[89,127,122]	5	hSpCas9	negative selection	1593024
237330924	237330947	1	-	26627737	HeLa	viability after 15 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.4599181480788166	[737]	[549,515,151]	4	hSpCas9	negative selection	1593027
237369590	237369613	1	-	26627737	HeLa	viability after 15 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.07531957116404409	[674]	[307,310,245]	0	hSpCas9	negative selection	1593029
237374728	237374751	1	-	26627737	HeLa	viability after 15 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.01635483872081367	[523]	[139,234,277]	0	hSpCas9	negative selection	1593030
237377352	237377375	1	+	26627737	HeLa	viability after 15 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1593031
237042510	237042533	1	+	26627737	HeLa	viability after 18 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.6050894747297838	[703]	[80,245,144]	-5	hSpCas9	negative selection	1675336
237270548	237270571	1	+	26627737	HeLa	viability after 18 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.5986733618745855	[181]	[54,109,122]	5	hSpCas9	negative selection	1675339
237330924	237330947	1	-	26627737	HeLa	viability after 18 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.4558901189301674	[737]	[366,426,151]	4	hSpCas9	negative selection	1675342
237369590	237369613	1	-	26627737	HeLa	viability after 18 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.09245599992712317	[674]	[216,252,245]	0	hSpCas9	negative selection	1675344
237374728	237374751	1	-	26627737	HeLa	viability after 18 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.022514746955846376	[523]	[92,197,277]	0	hSpCas9	negative selection	1675345
237377352	237377375	1	+	26627737	HeLa	viability after 18 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1675346
237042510	237042533	1	+	26627737	HCT116	viability after 6 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.2224997048494838	[677]	[231,64]	1	hSpCas9	negative selection	1757651
237270548	237270571	1	+	26627737	HCT116	viability after 6 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.5667213687086565	[251]	[126,20]	3	hSpCas9	negative selection	1757654
237330924	237330947	1	-	26627737	HCT116	viability after 6 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.19607476767407783	[1077]	[281,73]	-1	hSpCas9	negative selection	1757657
237369590	237369613	1	-	26627737	HCT116	viability after 6 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	1.029765699110158	[801]	[288,239]	5	hSpCas9	negative selection	1757659
237374728	237374751	1	-	26627737	HCT116	viability after 6 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.5142236601888782	[723]	[196,14]	-3	hSpCas9	negative selection	1757660
237377352	237377375	1	+	26627737	HCT116	viability after 6 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1757661
237042510	237042533	1	+	26627737	HCT116	viability after 8 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.9507805948551624	[117]	[47,147,178]	8	hSpCas9	negative selection	1839966
237270548	237270571	1	+	26627737	HCT116	viability after 8 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.7140919232102418	[261]	[129,65,68]	-7	hSpCas9	negative selection	1839969
237330924	237330947	1	-	26627737	HCT116	viability after 8 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	1.1227919431593587	[318]	[348,435,362]	8	hSpCas9	negative selection	1839972
237369590	237369613	1	-	26627737	HCT116	viability after 8 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.9024551465035089	[383]	[263,506,412]	7	hSpCas9	negative selection	1839974
237374728	237374751	1	-	26627737	HCT116	viability after 8 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.6642120333798158	[139]	[241,291,199]	9	hSpCas9	negative selection	1839975
237377352	237377375	1	+	26627737	HCT116	viability after 8 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1839976
237042510	237042533	1	+	26627737	HCT116	viability after 9 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.49660208572874043	[677]	[110,141]	-4	hSpCas9	negative selection	1922281
237270548	237270571	1	+	26627737	HCT116	viability after 9 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.08780750248817748	[251]	[107,27]	0	hSpCas9	negative selection	1922284
237330924	237330947	1	-	26627737	HCT116	viability after 9 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.5528712168588049	[1077]	[495,363]	4	hSpCas9	negative selection	1922287
237369590	237369613	1	-	26627737	HCT116	viability after 9 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.5892553200049486	[801]	[391,266]	4	hSpCas9	negative selection	1922289
237374728	237374751	1	-	26627737	HCT116	viability after 9 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.11956082093706093	[723]	[187,169]	-1	hSpCas9	negative selection	1922290
237377352	237377375	1	+	26627737	HCT116	viability after 9 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1922291
237042510	237042533	1	+	26627737	HCT116	viability after 12 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.5938173713485999	[117]	[142,116,16]	5	hSpCas9	negative selection	2004596
237270548	237270571	1	+	26627737	HCT116	viability after 12 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.3323623597217057	[261]	[149,129,44]	-4	hSpCas9	negative selection	2004599
237330924	237330947	1	-	26627737	HCT116	viability after 12 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.7985650815509076	[318]	[247,348,282]	7	hSpCas9	negative selection	2004602
237369590	237369613	1	-	26627737	HCT116	viability after 12 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.6427799006379449	[383]	[275,410,263]	6	hSpCas9	negative selection	2004604
237374728	237374751	1	-	26627737	HCT116	viability after 12 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.5771095627933265	[139]	[172,274,215]	9	hSpCas9	negative selection	2004605
237377352	237377375	1	+	26627737	HCT116	viability after 12 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2004606
237042510	237042533	1	+	26627737	HCT116	viability after 15 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	1.0951729937825214	[117]	[93,176,156]	8	hSpCas9	negative selection	2086911
237270548	237270571	1	+	26627737	HCT116	viability after 15 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.35023734036598697	[261]	[158,74,124]	-4	hSpCas9	negative selection	2086914
237330924	237330947	1	-	26627737	HCT116	viability after 15 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.6659792044697518	[318]	[270,338,259]	6	hSpCas9	negative selection	2086917
237369590	237369613	1	-	26627737	HCT116	viability after 15 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.7597737662199997	[383]	[472,423,236]	6	hSpCas9	negative selection	2086919
237374728	237374751	1	-	26627737	HCT116	viability after 15 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	1.3736606801713844	[139]	[205,231,186]	9	hSpCas9	negative selection	2086920
237377352	237377375	1	+	26627737	HCT116	viability after 15 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2086921
237042510	237042533	1	+	26627737	HCT116	viability after 18 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	1.5714787804915538	[117]	[162,134,214]	9	hSpCas9	negative selection	2169226
237270548	237270571	1	+	26627737	HCT116	viability after 18 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	-0.5893180648265165	[261]	[116,66,68]	-5	hSpCas9	negative selection	2169229
237330924	237330947	1	-	26627737	HCT116	viability after 18 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.7815354503283076	[318]	[163,351,273]	6	hSpCas9	negative selection	2169232
237369590	237369613	1	-	26627737	HCT116	viability after 18 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.6131860360873382	[383]	[146,484,202]	5	hSpCas9	negative selection	2169234
237374728	237374751	1	-	26627737	HCT116	viability after 18 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.8798696829294356	[139]	[111,160,96]	7	hSpCas9	negative selection	2169235
237377352	237377375	1	+	26627737	HCT116	viability after 18 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2169236
237126192	237126215	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTTGG	RYR2	ENSG00000198626	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385650
237189921	237189944	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGTGATCTTAG	RYR2	ENSG00000198626	1.5299201678265226	[5,69]	[1,47]	6	dCas9-VP64	positive selection	2386407
237314137	237314160	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCACCTCCAGG	RYR2	ENSG00000198626	-1.3954490623194618	[659,580]	[75,24]	-7	dCas9-VP64	positive selection	2391132
237042292	237042315	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCCTGCTCCGCACTGTGCGG	RYR2	ENSG00000198626	1.3288787740691181	[332,399]	[80,333]	5	dCas9-VP64	positive selection	2391209
237042205	237042228	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGCAGCCGGCGGTCCGCTCGG	RYR2	ENSG00000198626	0.5419199123794767	[95,36]	[13,27]	2	dCas9-VP64	positive selection	2391210
237042252	237042275	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGCTTCCCCGCGTCCTCCGGG	RYR2	ENSG00000198626	-0.669945655162897	[279,136]	[35,19]	-3	dCas9-VP64	positive selection	2391211
237805454	237805477	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTGTAGTCCCAGCTACTCGGG	RYR2	ENSG00000198626	-0.8391819250206091	[111,80]	[9,12]	-5	dCas9-VP64	positive selection	2393378
237305646	237305669	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTTGAACTCCTGGGCTCAGG	RYR2	ENSG00000198626	4.2770735618878515	[141,50]	[775,15]	9	dCas9-VP64	positive selection	2397441
237665164	237665187	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGTGGATCACAAGG	RYR2	ENSG00000198626	2.1502832554388824	[230,177]	[276,116]	7	dCas9-VP64	positive selection	2400438
237308913	237308936	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATTTTGACAGGGTGCTGATTGG	RYR2	ENSG00000198626	-2.1572944504780103	[14,128]	[0,5]	-9	dCas9-VP64	positive selection	2402835
237683927	237683950	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTTCTTCTTCTTCTTTTGAGG	RYR2	ENSG00000198626	-1.035619929527766	[415,395]	[36,49]	-6	dCas9-VP64	positive selection	2404171
237381117	237381140	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCTACTAAG	RYR2	ENSG00000198626	-0.8190110364213175	[438,580]	[39,87]	-4	dCas9-VP64	positive selection	2406313
237216609	237216632	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCTACTTAG	RYR2	ENSG00000198626	-0.8190110364213175	[438,580]	[39,87]	-4	dCas9-VP64	positive selection	2406347
237246144	237246167	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCGGTGGCACAATCTTGG	RYR2	ENSG00000198626	0.34388664028494687	[9,101]	[1,29]	1	dCas9-VP64	positive selection	2425874
237539767	237539790	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATAGGTGCAGCAAACCACCATGG	RYR2	ENSG00000198626	9.45620005017045	[53,84]	[18082,3082]	9	dCas9-VP64	positive selection	2426915
237246055	237246078	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCACACCTGG	RYR2	ENSG00000198626	0.08350517940301261	[638,11]	[141,1]	0	dCas9-VP64	positive selection	2447580
237559444	237559467	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACCAGCCTGATCAACACAG	RYR2	ENSG00000198626	-0.08492757567810244	[180,53]	[21,25]	0	dCas9-VP64	positive selection	2451945
237540477	237540500	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTCAGATCACCTGAGGTCAGG	RYR2	ENSG00000198626	1.9587821222707034	[130,16]	[18,108]	7	dCas9-VP64	positive selection	2463610
237819569	237819592	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCTGAAGGGG	RYR2	ENSG00000198626	6.35516198632701	[126,1064]	[8429,13566]	9	dCas9-VP64	positive selection	2467075
237634191	237634214	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTAGGTTGATTCCATATCTCAG	RYR2	ENSG00000198626	-0.8883757219304182	[55,162]	[4,20]	-5	dCas9-VP64	positive selection	2471655
237126192	237126215	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTTGG	RYR2	ENSG00000198626	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480905
237189921	237189944	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGTGATCTTAG	RYR2	ENSG00000198626	0.46408056547853904	[52,55]	[23,24]	3	dCas9-VP64	positive selection	2481662
237314137	237314160	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCACCTCCAGG	RYR2	ENSG00000198626	0.22022123063307442	[237,267]	[67,121]	1	dCas9-VP64	positive selection	2486387
237042292	237042315	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCCTGCTCCGCACTGTGCGG	RYR2	ENSG00000198626	1.0329847901428804	[308,266]	[115,264]	6	dCas9-VP64	positive selection	2486464
237042205	237042228	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGCAGCCGGCGGTCCGCTCGG	RYR2	ENSG00000198626	0.28919794033195223	[227,212]	[67,106]	2	dCas9-VP64	positive selection	2486465
237042252	237042275	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGCTTCCCCGCGTCCTCCGGG	RYR2	ENSG00000198626	2.338751993274279	[310,298]	[870,162]	9	dCas9-VP64	positive selection	2486466
237805454	237805477	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTGTAGTCCCAGCTACTCGGG	RYR2	ENSG00000198626	1.1377968629765447	[99,72]	[76,47]	7	dCas9-VP64	positive selection	2488633
237305646	237305669	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTTGAACTCCTGGGCTCAGG	RYR2	ENSG00000198626	0.8672449668792414	[148,204]	[104,104]	6	dCas9-VP64	positive selection	2492696
237665164	237665187	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGTGGATCACAAGG	RYR2	ENSG00000198626	0.9222606626235144	[35,66]	[18,42]	6	dCas9-VP64	positive selection	2495693
237308913	237308936	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATTTTGACAGGGTGCTGATTGG	RYR2	ENSG00000198626	-1.2210369506279386	[162,359]	[26,44]	-9	dCas9-VP64	positive selection	2498090
237683927	237683950	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTTCTTCTTCTTCTTTTGAGG	RYR2	ENSG00000198626	-0.4893663509645687	[355,242]	[55,81]	-5	dCas9-VP64	positive selection	2499426
237381117	237381140	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCTACTAAG	RYR2	ENSG00000198626	0.2665454673496357	[718,321]	[136,269]	2	dCas9-VP64	positive selection	2501568
237216609	237216632	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCTACTTAG	RYR2	ENSG00000198626	0.2665454673496357	[718,321]	[136,269]	2	dCas9-VP64	positive selection	2501602
237246144	237246167	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCGGTGGCACAATCTTGG	RYR2	ENSG00000198626	-0.06548600402502203	[51,72]	[16,20]	0	dCas9-VP64	positive selection	2521129
237539767	237539790	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATAGGTGCAGCAAACCACCATGG	RYR2	ENSG00000198626	1.9932270680514117	[357,195]	[283,435]	8	dCas9-VP64	positive selection	2522170
237246055	237246078	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCACACCTGG	RYR2	ENSG00000198626	-0.14914508695783546	[201,22]	[49,17]	-1	dCas9-VP64	positive selection	2542835
237559444	237559467	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACCAGCCTGATCAACACAG	RYR2	ENSG00000198626	-0.6769120761823355	[84,46]	[15,9]	-6	dCas9-VP64	positive selection	2547200
237540477	237540500	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTCAGATCACCTGAGGTCAGG	RYR2	ENSG00000198626	1.9179472110814313	[69,68]	[20,145]	8	dCas9-VP64	positive selection	2558865
237819569	237819592	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCTGAAGGGG	RYR2	ENSG00000198626	6.970706058095935	[220,255]	[14367,5508]	9	dCas9-VP64	positive selection	2562330
237634191	237634214	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTAGGTTGATTCCATATCTCAG	RYR2	ENSG00000198626	-0.1306876359303103	[167,77]	[46,26]	-1	dCas9-VP64	positive selection	2566910
237550613	237550636	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	0.23166831238505048	[1,1]	[1,1]	5	hSpCas9	positive selection	3018415
237566570	237566593	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	0.008669422142838779	[2,2]	[0,3]	0	hSpCas9	positive selection	3018416
237330947	237330970	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.466626533361975	[2,3]	[3,4]	8	hSpCas9	positive selection	3018417
237503487	237503510	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	0.23228736917175774	[3,4]	[4,3]	5	hSpCas9	positive selection	3018418
237550613	237550636	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	-0.018386684299209866	[1,1]	[0,0]	0	hSpCas9	positive selection	3086273
237566570	237566593	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	-0.1821621773299694	[2,2]	[1,1]	-3	hSpCas9	positive selection	3086274
237330947	237330970	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.011012581895065543	[2,2]	[1,1]	0	hSpCas9	positive selection	3086275
237503487	237503510	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	0.7593347326499658	[3,3]	[4,5]	9	hSpCas9	positive selection	3086276
237270606	237270629		-	24336571	A375	resistance to PLX after 7 days	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	-0.22054013499186742	[4,5]	[4,4]	-6	hSpCas9	positive selection	3142330
237270487	237270510		+	24336571	A375	resistance to PLX after 7 days	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.17151474014351398	[5,5]	[4,4]	-5	hSpCas9	positive selection	3142331
237042511	237042534		+	24336571	A375	resistance to PLX after 7 days	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.2683112240165958	[9,11]	[7,9]	-7	hSpCas9	positive selection	3142332
237270574	237270597		+	24336571	A375	resistance to PLX after 7 days	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	0.12851071759716048	[23,22]	[24,25]	4	hSpCas9	positive selection	3142333
237270606	237270629		-	24336571	A375	resistance to PLX after 14 days	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	0.5416739451592163	[1,4]	[2,1]	5	hSpCas9	positive selection	3200123
237270487	237270510		+	24336571	A375	resistance to PLX after 14 days	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.4778373890363179	[2,4]	[1,1]	4	hSpCas9	positive selection	3200124
237042511	237042534		+	24336571	A375	resistance to PLX after 14 days	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.44624205972335257	[6,15]	[7,5]	4	hSpCas9	positive selection	3200125
237270574	237270597		+	24336571	A375	resistance to PLX after 14 days	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	-0.2823417623152906	[35,25]	[11,11]	-3	hSpCas9	positive selection	3200126
237270606	237270629		-	24336571	A375	viability after 7 days	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	-0.663872903355774	[9]	[4,5]	-7	hSpCas9	negative selection	3257916
237270487	237270510		+	24336571	A375	viability after 7 days	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.15270171089959894	[5]	[5,5]	2	hSpCas9	negative selection	3257917
237042511	237042534		+	24336571	A375	viability after 7 days	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.212001041327662	[9]	[9,11]	3	hSpCas9	negative selection	3257918
237270574	237270597		+	24336571	A375	viability after 7 days	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	0.7275788435669691	[14]	[23,22]	9	hSpCas9	negative selection	3257919
237270606	237270629		-	24336571	A375	viability after 14 days	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	-1.2305777819589379	[9]	[1,4]	-9	hSpCas9	negative selection	3315709
237270487	237270510		+	24336571	A375	viability after 14 days	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.347718438048646	[5]	[2,4]	-4	hSpCas9	negative selection	3315710
237042511	237042534		+	24336571	A375	viability after 14 days	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.3065155773421933	[9]	[6,15]	4	hSpCas9	negative selection	3315711
237270574	237270597		+	24336571	A375	viability after 14 days	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	1.1238466294744396	[14]	[35,25]	9	hSpCas9	negative selection	3315712
237270600	237270623	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3391005
237270487	237270510	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.748298337748043	[256,256]	[0,0]	-5	hSpCas9	positive selection	3391006
237374721	237374744	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.537089654904271	[221,221]	[0,0]	-4	hSpCas9	positive selection	3391007
237550612	237550635	1	+	26780180	HT29	viability (Avana library 4 designs)	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	1.70275291732736	[]	[]	6	hSpCas9	negative selection	3456813
237566569	237566592	1	+	26780180	HT29	viability (Avana library 4 designs)	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	1.33531939728847	[]	[]	5	hSpCas9	negative selection	3456814
237330946	237330969	1	+	26780180	HT29	viability (Avana library 4 designs)	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	1.22792706149219	[]	[]	5	hSpCas9	negative selection	3456815
237503487	237503510	1	-	26780180	HT29	viability (Avana library 4 designs)	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	0.427275204761132	[]	[]	1	hSpCas9	negative selection	3456816
237503487	237503510	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	3.64790762121508	[]	[]	6	hSpCas9	negative selection	3555466
237330946	237330969	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.604075319933571	[]	[]	0	hSpCas9	negative selection	3555467
237566569	237566592	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	3.47420242125388	[]	[]	5	hSpCas9	negative selection	3555468
237550612	237550635	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	5.89940752957164	[]	[]	9	hSpCas9	negative selection	3555469
237639130	237639153	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGCCATCAAAATCGCCGAGG	RYR2	ENSG00000198626	-0.762338698634334	[]	[]	-1	hSpCas9	negative selection	3555470
237614576	237614599	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGATGAGAGGTACAAAGAGG	RYR2	ENSG00000198626	-4.44181804767838	[]	[]	-5	hSpCas9	negative selection	3555471
237503487	237503510	1	-	26780180	A375	viability (Avana lentiGuide)	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	2.03637384620722	[]	[]	2	hSpCas9	negative selection	3664125
237330946	237330969	1	+	26780180	A375	viability (Avana lentiGuide)	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	4.44282240817665	[]	[]	4	hSpCas9	negative selection	3664126
237566569	237566592	1	+	26780180	A375	viability (Avana lentiGuide)	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	1.65590444292969	[]	[]	2	hSpCas9	negative selection	3664127
237550612	237550635	1	+	26780180	A375	viability (Avana lentiGuide)	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	14.57308035023	[]	[]	8	hSpCas9	negative selection	3664128
237639130	237639153	1	+	26780180	A375	viability (Avana lentiGuide)	AGAAGCCATCAAAATCGCCGAGG	RYR2	ENSG00000198626	0.542227608906466	[]	[]	0	hSpCas9	negative selection	3664129
237614576	237614599	1	-	26780180	A375	viability (Avana lentiGuide)	GCTTGATGAGAGGTACAAAGAGG	RYR2	ENSG00000198626	-10.028281114184	[]	[]	-9	hSpCas9	negative selection	3664130
237503487	237503510	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	0.20001687486323227	[5]	[6,5]	5	hSpCas9	positive selection	3772732
237330946	237330969	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.14327224245862938	[4]	[4,3]	-2	hSpCas9	positive selection	3772733
237566569	237566592	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	-0.3319143555902583	[3]	[3,1]	-5	hSpCas9	positive selection	3772734
237550612	237550635	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	0.49632045583510126	[3]	[5,4]	9	hSpCas9	positive selection	3772735
237639130	237639153	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGCCATCAAAATCGCCGAGG	RYR2	ENSG00000198626	-0.11398247105133896	[4]	[4,3]	-2	hSpCas9	positive selection	3772736
237614576	237614599	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGATGAGAGGTACAAAGAGG	RYR2	ENSG00000198626	-0.5497732362367791	[4]	[2,2]	-7	hSpCas9	positive selection	3772737
237503487	237503510	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCTGGCTGGTATCCACAGGG	RYR2	ENSG00000198626	-0.1927136983095516	[5]	[4,3]	-3	hSpCas9	positive selection	3881339
237330946	237330969	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.4161926479212852	[4]	[2,2]	-5	hSpCas9	positive selection	3881340
237566569	237566592	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGAGCCGAAGTGTGCAGCGG	RYR2	ENSG00000198626	0.3080347973490339	[4]	[5,3]	8	hSpCas9	positive selection	3881341
237550612	237550635	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAACAAGGACAGCCTCCGCGAGG	RYR2	ENSG00000198626	-1.0260894541245833	[3]	[0,0]	-8	hSpCas9	positive selection	3881342
237639130	237639153	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGCCATCAAAATCGCCGAGG	RYR2	ENSG00000198626	-0.3509120881036945	[5]	[2,3]	-4	hSpCas9	positive selection	3881343
237614576	237614599	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGATGAGAGGTACAAAGAGG	RYR2	ENSG00000198626	0.2116796582485302	[4]	[4,3]	5	hSpCas9	positive selection	3881344
237374740	237374763	1	-	26780180	A375	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.909487480667968	[]	[]	4	hSpCas9	negative selection	3991371
237270487	237270510	1	+	26780180	A375	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	1.11822120330109	[]	[]	5	hSpCas9	negative selection	3991372
237042554	237042577	1	-	26780180	A375	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.658662244728874	[]	[]	2	hSpCas9	negative selection	3991373
237042511	237042534	1	+	26780180	A375	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.890599982412879	[]	[]	4	hSpCas9	negative selection	3991374
237270600	237270623	1	-	26780180	A375	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	1.28822217843605	[]	[]	7	hSpCas9	negative selection	3991375
237374721	237374744	1	+	26780180	A375	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	1.92994420103476	[]	[]	9	hSpCas9	negative selection	3991376
237374740	237374763	1	-	26780180	HT29	viability (GeCKOv2 library)	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	1.14304556445481	[]	[]	5	hSpCas9	negative selection	4099337
237270487	237270510	1	+	26780180	HT29	viability (GeCKOv2 library)	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.629906631371004	[]	[]	2	hSpCas9	negative selection	4099338
237042554	237042577	1	-	26780180	HT29	viability (GeCKOv2 library)	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	1.77451360405844	[]	[]	8	hSpCas9	negative selection	4099339
237042511	237042534	1	+	26780180	HT29	viability (GeCKOv2 library)	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.704058115120685	[]	[]	2	hSpCas9	negative selection	4099340
237270600	237270623	1	-	26780180	HT29	viability (GeCKOv2 library)	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.0838853067678551	[]	[]	0	hSpCas9	negative selection	4099341
237374721	237374744	1	+	26780180	HT29	viability (GeCKOv2 library)	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	1.63474908732316	[]	[]	8	hSpCas9	negative selection	4099342
237270606	237270629	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	-0.5391510349603514	[3]	[1,0]	-8	hSpCas9	positive selection	4168057
237270487	237270510	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.33703246341705567	[2]	[0,0]	-7	hSpCas9	positive selection	4168058
237042511	237042534	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.012235683639214207	[3]	[1,2]	0	hSpCas9	positive selection	4168059
237270574	237270597	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	0.1863298162062065	[4]	[3,3]	5	hSpCas9	positive selection	4168060
237270606	237270629	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTCATCCCACCTTGGAATTGG	RYR2	ENSG00000198626	0.9402707553178448	[3]	[2,1,1,3]	6	hSpCas9	positive selection	4232079
237270487	237270510	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.07483024435218633	[1]	[0,0,0,0]	-1	hSpCas9	positive selection	4232080
237042511	237042534	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	1.0340289242424523	[1]	[3,2,0,0]	7	hSpCas9	positive selection	4232081
237270574	237270597	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGCAACAGACTTTGTTTCTTGG	RYR2	ENSG00000198626	-0.01703120567999236	[4]	[4,1,0,0]	0	hSpCas9	positive selection	4232082
237042511	237042534	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.10469179949363294	[1]	[2,0]	-2	hSpCas9	positive selection	4296154
237042554	237042577	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.19014989505577237	[3]	[3,2]	4	hSpCas9	positive selection	4296155
237374740	237374763	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.11947578701598487	[2]	[2,1]	2	hSpCas9	positive selection	4296156
237270600	237270623	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.0266651502606446	[3]	[3,1]	0	hSpCas9	positive selection	4360408
237270487	237270510	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.027445538487441967	[3]	[3,1]	0	hSpCas9	positive selection	4360409
237374721	237374744	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.28025456807635735	[2]	[1,1]	-5	hSpCas9	positive selection	4360410
237423123	237423145	1	-	27760321	OCIAML3	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	1.361880434247341	[258,221]	[461,507]	9	hSpCas9	negative selection	4436517
237566710	237566732	1	-	27760321	OCIAML3	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.43306579401233386	[422,389]	[390,478]	5	hSpCas9	negative selection	4436518
237590745	237590767	1	+	27760321	OCIAML3	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.6260821408406319	[844,716]	[678,1278]	7	hSpCas9	negative selection	4436519
237617318	237617340	1	-	27760321	OCIAML3	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.18381413657923257	[548,594]	[461,575]	2	hSpCas9	negative selection	4436520
237627959	237627981	1	+	27760321	OCIAML3	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	0.25508684437798135	[553,512]	[418,600]	3	hSpCas9	negative selection	4436521
237423123	237423145	1	-	27760321	OCIAML2	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	-0.5519589998877497	[258,221]	[108,162]	-6	hSpCas9	negative selection	4519980
237566710	237566732	1	-	27760321	OCIAML2	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.18986229528600024	[422,389]	[321,444]	2	hSpCas9	negative selection	4519981
237590745	237590767	1	+	27760321	OCIAML2	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.35875096446197574	[844,716]	[689,961]	5	hSpCas9	negative selection	4519982
237617318	237617340	1	-	27760321	OCIAML2	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.12489297923316417	[548,594]	[481,541]	1	hSpCas9	negative selection	4519983
237627959	237627981	1	+	27760321	OCIAML2	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.11007530428894016	[553,512]	[326,495]	-1	hSpCas9	negative selection	4519984
237423123	237423145	1	-	27760321	MV411	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.960492168513827	[258,221]	[430,122]	7	hSpCas9	negative selection	4603443
237566710	237566732	1	-	27760321	MV411	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	-0.14657401454745933	[422,389]	[149,380]	-1	hSpCas9	negative selection	4603444
237590745	237590767	1	+	27760321	MV411	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	1.2507034194302578	[844,716]	[1184,1277]	8	hSpCas9	negative selection	4603445
237617318	237617340	1	-	27760321	MV411	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	-0.12486964710940107	[548,594]	[162,626]	-1	hSpCas9	negative selection	4603446
237627959	237627981	1	+	27760321	MV411	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.07627060837134386	[553,512]	[299,384]	0	hSpCas9	negative selection	4603447
237423123	237423145	1	-	27760321	HL60	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.2547225316300624	[258,221]	[272,191]	3	hSpCas9	negative selection	4686906
237566710	237566732	1	-	27760321	HL60	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.23158546160333382	[422,389]	[318,464]	3	hSpCas9	negative selection	4686907
237590745	237590767	1	+	27760321	HL60	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.30507630557092513	[844,716]	[768,802]	4	hSpCas9	negative selection	4686908
237617318	237617340	1	-	27760321	HL60	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.171303018885741	[548,594]	[566,489]	2	hSpCas9	negative selection	4686909
237627959	237627981	1	+	27760321	HL60	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	0.4651240927810645	[553,512]	[590,612]	5	hSpCas9	negative selection	4686910
237423123	237423145	1	-	27760321	HT1080	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	-1.340158638845954	[221,172]	[0,63]	-5	hSpCas9	negative selection	4770369
237566710	237566732	1	-	27760321	HT1080	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	1.3662931888324423	[389,304]	[460,242]	7	hSpCas9	negative selection	4770370
237590745	237590767	1	+	27760321	HT1080	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	1.4082433185720462	[716,559]	[540,821]	7	hSpCas9	negative selection	4770371
237617318	237617340	1	-	27760321	HT1080	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.9821483295678165	[594,463]	[514,308]	5	hSpCas9	negative selection	4770372
237627959	237627981	1	+	27760321	HT1080	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.696983289453046	[512,400]	[139,81]	-3	hSpCas9	negative selection	4770373
237423123	237423145	1	-	27760321	HT29	viability after 7 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.5119216783775389	[221,172]	[294,352,425]	7	hSpCas9	negative selection	4853832
237566710	237566732	1	-	27760321	HT29	viability after 7 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.8980169001893641	[389,304]	[490,960,990]	9	hSpCas9	negative selection	4853833
237590745	237590767	1	+	27760321	HT29	viability after 7 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.29822848811936764	[716,559]	[1401,799,884]	4	hSpCas9	negative selection	4853834
237617318	237617340	1	-	27760321	HT29	viability after 7 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	-0.30973142742101	[594,463]	[602,643,411]	-4	hSpCas9	negative selection	4853835
237627959	237627981	1	+	27760321	HT29	viability after 7 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.2359592106538826	[512,400]	[499,359,631]	-3	hSpCas9	negative selection	4853836
237423123	237423145	1	-	27760321	HT29	viability after 25 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.6844098646392037	[221,172]	[144,336,648]	7	hSpCas9	negative selection	4937295
237566710	237566732	1	-	27760321	HT29	viability after 25 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.7806087186863845	[389,304]	[657,744,639]	8	hSpCas9	negative selection	4937296
237590745	237590767	1	+	27760321	HT29	viability after 25 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.7688547203902237	[716,559]	[1092,1002,1687]	8	hSpCas9	negative selection	4937297
237617318	237617340	1	-	27760321	HT29	viability after 25 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.21840386755288166	[594,463]	[559,898,655]	2	hSpCas9	negative selection	4937298
237627959	237627981	1	+	27760321	HT29	viability after 25 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.07267449293989242	[512,400]	[390,477,641]	-1	hSpCas9	negative selection	4937299
237423123	237423145	1	-	27760321	HT29	viability after 22 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.5800883002274821	[221,172]	[339,331,351]	6	hSpCas9	negative selection	5020758
237566710	237566732	1	-	27760321	HT29	viability after 22 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.5518409786161173	[389,304]	[600,640,523]	6	hSpCas9	negative selection	5020759
237590745	237590767	1	+	27760321	HT29	viability after 22 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.6251670241941355	[716,559]	[846,1173,1404]	7	hSpCas9	negative selection	5020760
237617318	237617340	1	-	27760321	HT29	viability after 22 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	-0.3321631952909021	[594,463]	[335,607,518]	-3	hSpCas9	negative selection	5020761
237627959	237627981	1	+	27760321	HT29	viability after 22 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.050990730898143155	[512,400]	[420,437,674]	0	hSpCas9	negative selection	5020762
237423123	237423145	1	-	27760321	HT29	viability after 19 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.08585692173411008	[221,172]	[142,169,389]	0	hSpCas9	negative selection	5104221
237566710	237566732	1	-	27760321	HT29	viability after 19 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.3069715964561873	[389,304]	[396,899,179]	3	hSpCas9	negative selection	5104222
237590745	237590767	1	+	27760321	HT29	viability after 19 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.9063785371722969	[716,559]	[931,1365,1746]	8	hSpCas9	negative selection	5104223
237617318	237617340	1	-	27760321	HT29	viability after 19 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	-0.22237215114775838	[594,463]	[621,330,610]	-2	hSpCas9	negative selection	5104224
237627959	237627981	1	+	27760321	HT29	viability after 19 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.1033794497165933	[512,400]	[322,786,337]	-1	hSpCas9	negative selection	5104225
237423123	237423145	1	-	27760321	HT29	viability after 16 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.26337466190163383	[221,172]	[215,375,195]	3	hSpCas9	negative selection	5187684
237566710	237566732	1	-	27760321	HT29	viability after 16 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.8335671127436326	[389,304]	[745,719,616]	8	hSpCas9	negative selection	5187685
237590745	237590767	1	+	27760321	HT29	viability after 16 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.7297860042424894	[716,559]	[1520,831,1241]	8	hSpCas9	negative selection	5187686
237617318	237617340	1	-	27760321	HT29	viability after 16 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.03767792861729047	[594,463]	[706,546,580]	0	hSpCas9	negative selection	5187687
237627959	237627981	1	+	27760321	HT29	viability after 16 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	0.24185398461505397	[512,400]	[390,708,690]	2	hSpCas9	negative selection	5187688
237423123	237423145	1	-	27760321	HT29	viability after 13 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.28731157508494487	[221,172]	[329,184,320]	3	hSpCas9	negative selection	5271147
237566710	237566732	1	-	27760321	HT29	viability after 13 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.49335757239323547	[389,304]	[530,506,658]	6	hSpCas9	negative selection	5271148
237590745	237590767	1	+	27760321	HT29	viability after 13 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.5975024033857953	[716,559]	[984,1228,1146]	7	hSpCas9	negative selection	5271149
237617318	237617340	1	-	27760321	HT29	viability after 13 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	-0.13837095660139598	[594,463]	[622,595,460]	-2	hSpCas9	negative selection	5271150
237627959	237627981	1	+	27760321	HT29	viability after 13 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	-0.2578274189194747	[512,400]	[362,345,610]	-3	hSpCas9	negative selection	5271151
237423123	237423145	1	-	27760321	HT29	viability after 10 days	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.12774678174530318	[221,172]	[245,256,303]	1	hSpCas9	negative selection	5354610
237566710	237566732	1	-	27760321	HT29	viability after 10 days	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	0.3523332630570884	[389,304]	[513,595,552]	5	hSpCas9	negative selection	5354611
237590745	237590767	1	+	27760321	HT29	viability after 10 days	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.5870061301095538	[716,559]	[1152,1548,906]	7	hSpCas9	negative selection	5354612
237617318	237617340	1	-	27760321	HT29	viability after 10 days	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.12906131413972222	[594,463]	[656,597,905]	1	hSpCas9	negative selection	5354613
237627959	237627981	1	+	27760321	HT29	viability after 10 days	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	0.0282926239395761	[512,400]	[641,439,657]	0	hSpCas9	negative selection	5354614
237423123	237423145	1	-	27760321	MOLM13	viability	TGACATGGCGTAGTCGGAATGG	RYR2	ENSG00000198626	0.7295660435209419	[258,221]	[125,307]	5	hSpCas9	negative selection	5438073
237566710	237566732	1	-	27760321	MOLM13	viability	CCTGATCCGGTTGACAACCAGG	RYR2	ENSG00000198626	1.3840407852536927	[422,389]	[200,936]	8	hSpCas9	negative selection	5438074
237590745	237590767	1	+	27760321	MOLM13	viability	AGCATGCCGATCGAGTGCGCGG	RYR2	ENSG00000198626	0.44497158164867345	[844,716]	[573,617]	3	hSpCas9	negative selection	5438075
237617318	237617340	1	-	27760321	MOLM13	viability	TTCTATCCGGTGCCGGACCTGG	RYR2	ENSG00000198626	0.6533197996469831	[548,594]	[612,423]	4	hSpCas9	negative selection	5438076
237627959	237627981	1	+	27760321	MOLM13	viability	ACGATAAATGGTGTGTCCGTGG	RYR2	ENSG00000198626	0.6727200466365044	[553,512]	[763,237]	4	hSpCas9	negative selection	5438077
237042198	237042221	1	+	27661255	K562	viability	GCCGGGGCCGAGCGGACCGCCGG	RYR2	ENSG00000198626	0.27241533932755135	[463,538]	[535,436]	8	dCas9-KRAB	negative selection	5509073
237042608	237042631	1	+	27661255	K562	viability	GGCGTCAGGGCATCCACTAGCGG	RYR2	ENSG00000198626	0.20696996734727724	[1210,1434]	[1207,1222]	7	dCas9-KRAB	negative selection	5509074
237042616	237042639	1	+	27661255	K562	viability	GGCATCCACTAGCGGGGTCCGGG	RYR2	ENSG00000198626	0.19590373662261507	[945,1448]	[1115,1062]	6	dCas9-KRAB	negative selection	5509075
237042773	237042796	1	+	27661255	K562	viability	GCGCGCGTGTGGAAAGCTAGAGG	RYR2	ENSG00000198626	0.16466464753921828	[351,409]	[323,353]	6	dCas9-KRAB	negative selection	5509076
237042820	237042843	1	+	27661255	K562	viability	GGCGCCCGGGCTCGGACCCGGGG	RYR2	ENSG00000198626	0.03174829235244392	[273,322]	[289,202]	1	dCas9-KRAB	negative selection	5509077
237042862	237042885	1	+	27661255	K562	viability	GGAGCTGCGGGAACCGGGAGAGG	RYR2	ENSG00000198626	-0.6134382365431532	[878,1120]	[548,494]	-8	dCas9-KRAB	negative selection	5509078
237042259	237042282	1	-	27661255	K562	viability	GCCCGGGCCCGGAGGACGCGGGG	RYR2	ENSG00000198626	-0.5725186935248157	[543,491]	[288,269]	-8	dCas9-KRAB	negative selection	5509079
237042511	237042534	1	+	27260156	BXPC3	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.05342985575812009	[170]	[125,161,215,192]	-1	hSpCas9	negative selection	5568614
237042554	237042577	1	-	27260156	BXPC3	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.0633228189067081	[776]	[950,728,851,853]	1	hSpCas9	negative selection	5568615
237374740	237374763	1	-	27260156	BXPC3	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.20375218940962445	[368]	[251,499,513,538]	4	hSpCas9	negative selection	5568616
237270600	237270623	1	-	27260156	BXPC3	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.15083995646244155	[557]	[585,608,583,838]	3	hSpCas9	negative selection	5632868
237270487	237270510	1	+	27260156	BXPC3	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.04255313266449856	[840]	[885,762,849,919]	-1	hSpCas9	negative selection	5632869
237374721	237374744	1	+	27260156	BXPC3	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.23172878906333916	[388]	[324,272,385,414]	-5	hSpCas9	negative selection	5632870
237042511	237042534	1	+	27260156	A673	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.002625628504283828	[170]	[230,179,192,219]	0	hSpCas9	negative selection	5689865
237042554	237042577	1	-	27260156	A673	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.031772399669835805	[776]	[907,864,831,1052]	-1	hSpCas9	negative selection	5689866
237374740	237374763	1	-	27260156	A673	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.13881209621463056	[368]	[539,364,650,396]	3	hSpCas9	negative selection	5689867
237270600	237270623	1	-	27260156	A673	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.29569233130190586	[557]	[891,727,712,974]	7	hSpCas9	negative selection	5754119
237270487	237270510	1	+	27260156	A673	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.06570397288225749	[840]	[1106,983,1037,1106]	1	hSpCas9	negative selection	5754120
237374721	237374744	1	+	27260156	A673	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.018973583561131435	[388]	[466,456,426,494]	0	hSpCas9	negative selection	5754121
237042511	237042534	1	+	27260156	A375	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.2991103869068461	[170]	[199,220,410,156]	4	hSpCas9	negative selection	5811116
237042554	237042577	1	-	27260156	A375	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.2258572063653863	[776]	[996,1356,932,1001]	3	hSpCas9	negative selection	5811117
237374740	237374763	1	-	27260156	A375	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.010906811712296571	[368]	[380,602,437,346]	0	hSpCas9	negative selection	5811118
237270600	237270623	1	-	27260156	A375	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.1378283757055841	[557]	[859,539,352,606]	-2	hSpCas9	negative selection	5875370
237270487	237270510	1	+	27260156	A375	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.49654425656803225	[840]	[550,765,750,719]	-6	hSpCas9	negative selection	5875371
237374721	237374744	1	+	27260156	A375	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.27630167351963153	[388]	[697,537,612,370]	4	hSpCas9	negative selection	5875372
237042511	237042534	1	+	27260156	COLO741	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.2272249084619582	[170]	[307,206,255]	5	hSpCas9	negative selection	5932367
237042554	237042577	1	-	27260156	COLO741	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.09166696950055542	[776]	[967,841,981]	-2	hSpCas9	negative selection	5932368
237374740	237374763	1	-	27260156	COLO741	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.2815389848352118	[368]	[478,655,574]	6	hSpCas9	negative selection	5932369
237270600	237270623	1	-	27260156	COLO741	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.009235130241854322	[557]	[658,836,654]	0	hSpCas9	negative selection	5996621
237270487	237270510	1	+	27260156	COLO741	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.1535791637412497	[840]	[1112,952,850]	-3	hSpCas9	negative selection	5996622
237374721	237374744	1	+	27260156	COLO741	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.06792122366366132	[388]	[582,380,466]	-1	hSpCas9	negative selection	5996623
237042511	237042534	1	+	27260156	CAL120	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.271661956143443	[170]	[284,301,188]	4	hSpCas9	negative selection	6053618
237042554	237042577	1	-	27260156	CAL120	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.20692216761430082	[776]	[1585,924,910]	3	hSpCas9	negative selection	6053619
237374740	237374763	1	-	27260156	CAL120	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.5844433281423416	[368]	[440,672,909]	8	hSpCas9	negative selection	6053620
237270600	237270623	1	-	27260156	CAL120	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.7091327491110864	[557]	[1138,1376,893]	9	hSpCas9	negative selection	6117872
237270487	237270510	1	+	27260156	CAL120	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.567983487590277	[840]	[827,662,645]	-7	hSpCas9	negative selection	6117873
237374721	237374744	1	+	27260156	CAL120	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.026737838900614874	[388]	[418,640,358]	0	hSpCas9	negative selection	6117874
237042511	237042534	1	+	27260156	CADOES1	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.6067143746924708	[170]	[84,121,76,134]	-8	hSpCas9	negative selection	6174869
237042554	237042577	1	-	27260156	CADOES1	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.4384708591335498	[776]	[860,1339,925,783]	7	hSpCas9	negative selection	6174870
237374740	237374763	1	-	27260156	CADOES1	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.34760061762438244	[368]	[423,402,322,602]	6	hSpCas9	negative selection	6174871
237270600	237270623	1	-	27260156	CADOES1	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.08844169498210477	[557]	[495,515,545,652]	1	hSpCas9	negative selection	6239123
237270487	237270510	1	+	27260156	CADOES1	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.20061924133261266	[840]	[553,798,742,624]	-3	hSpCas9	negative selection	6239124
237374721	237374744	1	+	27260156	CADOES1	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.07128299672357893	[388]	[381,391,327,419]	1	hSpCas9	negative selection	6239125
237042511	237042534	1	+	27260156	EWS502	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.039472867715534266	[170]	[86,263,177,182]	0	hSpCas9	negative selection	6296120
237042554	237042577	1	-	27260156	EWS502	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.13480103142463173	[776]	[651,809,702,845]	-2	hSpCas9	negative selection	6296121
237374740	237374763	1	-	27260156	EWS502	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.023582833331644515	[368]	[318,371,408,449]	0	hSpCas9	negative selection	6296122
237270600	237270623	1	-	27260156	EWS502	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.3305067950205809	[557]	[785,618,658,916]	6	hSpCas9	negative selection	6360374
237270487	237270510	1	+	27260156	EWS502	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.13244812076162893	[840]	[838,811,775,816]	-2	hSpCas9	negative selection	6360375
237374721	237374744	1	+	27260156	EWS502	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.05041156869896246	[388]	[419,312,523,456]	0	hSpCas9	negative selection	6360376
237042511	237042534	1	+	27260156	EW8	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.2446052376578558	[170]	[130,123,117,95]	-4	hSpCas9	negative selection	6417371
237042554	237042577	1	-	27260156	EW8	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.04854771519982137	[776]	[722,537,688,653]	0	hSpCas9	negative selection	6417372
237374740	237374763	1	-	27260156	EW8	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.004239854998420056	[368]	[320,289,317,261]	0	hSpCas9	negative selection	6417373
237270600	237270623	1	-	27260156	EW8	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.23427483881538416	[557]	[637,421,473,612]	4	hSpCas9	negative selection	6481625
237270487	237270510	1	+	27260156	EW8	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.25009766173159664	[840]	[846,474,469,545]	-5	hSpCas9	negative selection	6481626
237374721	237374744	1	+	27260156	EW8	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.24928313770983285	[388]	[318,298,331,547]	4	hSpCas9	negative selection	6481627
237042511	237042534	1	+	27260156	CORL105	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.4579984228128886	[170]	[299,292,302,208]	8	hSpCas9	negative selection	6538622
237042554	237042577	1	-	27260156	CORL105	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.13199792878447292	[776]	[952,1055,1245,768]	2	hSpCas9	negative selection	6538623
237374740	237374763	1	-	27260156	CORL105	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.470507064265801	[368]	[524,574,538,742]	8	hSpCas9	negative selection	6538624
237270600	237270623	1	-	27260156	CORL105	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.2229885137960235	[557]	[824,698,1000,565]	4	hSpCas9	negative selection	6602876
237270487	237270510	1	+	27260156	CORL105	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.18830313078062433	[840]	[748,854,915,939]	-3	hSpCas9	negative selection	6602877
237374721	237374744	1	+	27260156	CORL105	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.0844824662667531	[388]	[513,513,382,504]	1	hSpCas9	negative selection	6602878
237042511	237042534	1	+	27260156	HS294T	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.5826551712338229	[170]	[137,67,72,116]	7	hSpCas9	negative selection	6659873
237042554	237042577	1	-	27260156	HS294T	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.2467244682743016	[776]	[274,467,287,405]	3	hSpCas9	negative selection	6659874
237374740	237374763	1	-	27260156	HS294T	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.1950747125098175	[368]	[132,211,125,186]	2	hSpCas9	negative selection	6659875
237270600	237270623	1	-	27260156	HS294T	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.07841259882491217	[557]	[144,296,226,250]	1	hSpCas9	negative selection	6724127
237270487	237270510	1	+	27260156	HS294T	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.33587071683454994	[840]	[238,268,245,280]	-5	hSpCas9	negative selection	6724128
237374721	237374744	1	+	27260156	HS294T	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.1317740257554778	[388]	[81,170,136,167]	-2	hSpCas9	negative selection	6724129
237042511	237042534	1	+	27260156	HCC44	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.6688539135539848	[170]	[452,173,331,304]	9	hSpCas9	negative selection	6781124
237042554	237042577	1	-	27260156	HCC44	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.07247562322372603	[776]	[823,663,835,1028]	-1	hSpCas9	negative selection	6781125
237374740	237374763	1	-	27260156	HCC44	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.3234931063592277	[368]	[588,600,609,301]	5	hSpCas9	negative selection	6781126
237270600	237270623	1	-	27260156	HCC44	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.49478310894263333	[557]	[1314,527,860,929]	7	hSpCas9	negative selection	6845378
237270487	237270510	1	+	27260156	HCC44	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.1354783597461543	[840]	[940,792,1028,742]	-2	hSpCas9	negative selection	6845379
237374721	237374744	1	+	27260156	HCC44	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.38384434351098595	[388]	[538,407,814,590]	6	hSpCas9	negative selection	6845380
237042511	237042534	1	+	27260156	G402	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.09833696865429431	[170]	[188,277,203,219]	1	hSpCas9	negative selection	6902375
237042554	237042577	1	-	27260156	G402	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.172872247571625	[776]	[1332,791,1118,1049]	2	hSpCas9	negative selection	6902376
237374740	237374763	1	-	27260156	G402	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.46370194767342804	[368]	[553,700,508,707]	6	hSpCas9	negative selection	6902377
237270600	237270623	1	-	27260156	G402	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.5767426508983774	[557]	[1224,1305,638,938]	7	hSpCas9	negative selection	6966629
237270487	237270510	1	+	27260156	G402	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.07251910893839075	[840]	[1454,1027,1320,583]	0	hSpCas9	negative selection	6966630
237374721	237374744	1	+	27260156	G402	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.1529468503546738	[388]	[437,325,452,481]	-2	hSpCas9	negative selection	6966631
237042511	237042534	1	+	27260156	L33	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.13667436647500986	[170]	[191,117,82,139]	3	hSpCas9	negative selection	7023626
237042554	237042577	1	-	27260156	L33	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.025933691837549455	[776]	[842,326,529,679]	0	hSpCas9	negative selection	7023627
237374740	237374763	1	-	27260156	L33	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.47099920801332934	[368]	[573,170,311,555]	8	hSpCas9	negative selection	7023628
237270600	237270623	1	-	27260156	L33	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.25196861159982575	[557]	[779,231,489,530]	5	hSpCas9	negative selection	7087880
237270487	237270510	1	+	27260156	L33	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.19645952703164649	[840]	[729,244,453,883]	-4	hSpCas9	negative selection	7087881
237374721	237374744	1	+	27260156	L33	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.11413570912141285	[388]	[325,164,308,465]	2	hSpCas9	negative selection	7087882
237042511	237042534	1	+	27260156	K562	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.36827258034795896	[170]	[134,166,219,247]	4	hSpCas9	negative selection	7144877
237042554	237042577	1	-	27260156	K562	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.47376135934948205	[776]	[1091,668,1404,687]	6	hSpCas9	negative selection	7144878
237374740	237374763	1	-	27260156	K562	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.7320802564772518	[368]	[454,669,515,532]	8	hSpCas9	negative selection	7144879
237270600	237270623	1	-	27260156	K562	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.1484322566379334	[557]	[465,651,274,408]	-2	hSpCas9	negative selection	7209131
237270487	237270510	1	+	27260156	K562	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.3132835177989092	[840]	[559,727,661,468]	-4	hSpCas9	negative selection	7209132
237374721	237374744	1	+	27260156	K562	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.009101475409336979	[388]	[346,387,338,303]	0	hSpCas9	negative selection	7209133
237042511	237042534	1	+	27260156	HT29	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.42583822468658394	[170]	[240,255,270,334]	8	hSpCas9	negative selection	7266128
237042554	237042577	1	-	27260156	HT29	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.10108425794206	[776]	[1052,834,914,739]	-2	hSpCas9	negative selection	7266129
237374740	237374763	1	-	27260156	HT29	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.34564271151913845	[368]	[599,521,590,561]	6	hSpCas9	negative selection	7266130
237270600	237270623	1	-	27260156	HT29	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.19730486590264742	[557]	[642,732,694,992]	4	hSpCas9	negative selection	7330382
237270487	237270510	1	+	27260156	HT29	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.011900164738663399	[840]	[1091,1136,1295,651]	0	hSpCas9	negative selection	7330383
237374721	237374744	1	+	27260156	HT29	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.06361037252354176	[388]	[551,499,475,454]	1	hSpCas9	negative selection	7330384
237042511	237042534	1	+	27260156	MHHES1	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.6712366455634704	[170]	[156,143,63,121]	-8	hSpCas9	negative selection	7387379
237042554	237042577	1	-	27260156	MHHES1	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.21386533378285033	[776]	[1484,931,1084,665]	4	hSpCas9	negative selection	7387380
237374740	237374763	1	-	27260156	MHHES1	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.21672784456001515	[368]	[504,250,401,287]	-4	hSpCas9	negative selection	7387381
237270600	237270623	1	-	27260156	MHHES1	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.16774727229783795	[557]	[685,619,922,594]	3	hSpCas9	negative selection	7451633
237270487	237270510	1	+	27260156	MHHES1	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.14235573552110292	[840]	[941,928,866,723]	-3	hSpCas9	negative selection	7451634
237374721	237374744	1	+	27260156	MHHES1	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.011537102342144723	[388]	[583,453,325,415]	0	hSpCas9	negative selection	7451635
237042511	237042534	1	+	27260156	MEWO	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.35514552351218076	[170]	[154,253,194]	7	hSpCas9	negative selection	7508630
237042554	237042577	1	-	27260156	MEWO	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.39342967130062045	[776]	[644,531,500]	-7	hSpCas9	negative selection	7508631
237374740	237374763	1	-	27260156	MEWO	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.10994162474308755	[368]	[420,367,337]	2	hSpCas9	negative selection	7508632
237270600	237270623	1	-	27260156	MEWO	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.23412414951854701	[557]	[749,465,652]	5	hSpCas9	negative selection	7572884
237270487	237270510	1	+	27260156	MEWO	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.06326781813003113	[840]	[733,811,708]	-1	hSpCas9	negative selection	7572885
237374721	237374744	1	+	27260156	MEWO	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.08698656968922014	[388]	[385,391,257]	-2	hSpCas9	negative selection	7572886
237042511	237042534	1	+	27260156	LNCAPCLONEFGC	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.35425628175135304	[170]	[191,149,236,221]	5	hSpCas9	negative selection	7629881
237042554	237042577	1	-	27260156	LNCAPCLONEFGC	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.5053722848444819	[776]	[1081,1084,1049,778]	7	hSpCas9	negative selection	7629882
237374740	237374763	1	-	27260156	LNCAPCLONEFGC	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.020523712642737002	[368]	[350,220,398,363]	0	hSpCas9	negative selection	7629883
237270600	237270623	1	-	27260156	LNCAPCLONEFGC	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.1506537976208862	[557]	[330,430,548,527]	-2	hSpCas9	negative selection	7694135
237270487	237270510	1	+	27260156	LNCAPCLONEFGC	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.691885728070061	[840]	[426,429,513,524]	-8	hSpCas9	negative selection	7694136
237374721	237374744	1	+	27260156	LNCAPCLONEFGC	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.20193858901548967	[388]	[328,357,663,312]	3	hSpCas9	negative selection	7694137
237042511	237042534	1	+	27260156	PANC0327	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.24943915712255849	[170]	[116,111,273,222]	3	hSpCas9	negative selection	7751132
237042554	237042577	1	-	27260156	PANC0327	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.2593363966074914	[776]	[676,506,712,426]	-4	hSpCas9	negative selection	7751133
237374740	237374763	1	-	27260156	PANC0327	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.10750760369765822	[368]	[461,256,306,209]	-2	hSpCas9	negative selection	7751134
237270600	237270623	1	-	27260156	PANC0327	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.22011977717051442	[557]	[625,311,824,584]	3	hSpCas9	negative selection	7815386
237270487	237270510	1	+	27260156	PANC0327	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.3726036274374492	[840]	[635,690,504,465]	-5	hSpCas9	negative selection	7815387
237374721	237374744	1	+	27260156	PANC0327	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.4337486100242147	[388]	[601,364,427,495]	6	hSpCas9	negative selection	7815388
237042511	237042534	1	+	27260156	NCIH2009	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.7807024739628864	[170]	[794,225,288]	9	hSpCas9	negative selection	7872383
237042554	237042577	1	-	27260156	NCIH2009	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.24949470280561903	[776]	[1616,1177,1140]	3	hSpCas9	negative selection	7872384
237374740	237374763	1	-	27260156	NCIH2009	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.3666987967884438	[368]	[1053,557,459]	5	hSpCas9	negative selection	7872385
237270600	237270623	1	-	27260156	NCIH2009	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.31586852643463803	[557]	[1236,933,791]	4	hSpCas9	negative selection	7936637
237270487	237270510	1	+	27260156	NCIH2009	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.13569369988460345	[840]	[1089,1224,892]	-2	hSpCas9	negative selection	7936638
237374721	237374744	1	+	27260156	NCIH2009	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.19547577391513082	[388]	[711,473,283]	-3	hSpCas9	negative selection	7936639
237042511	237042534	1	+	27260156	NCIH1373	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.6315119966198489	[170]	[528,164,148,105]	6	hSpCas9	negative selection	7993634
237042554	237042577	1	-	27260156	NCIH1373	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.6261573490853996	[776]	[1545,1028,1369,393]	6	hSpCas9	negative selection	7993635
237374740	237374763	1	-	27260156	NCIH1373	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.35728845074821186	[368]	[489,622,399,155]	3	hSpCas9	negative selection	7993636
237270600	237270623	1	-	27260156	NCIH1373	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.010851357101154202	[557]	[537,353,555,282]	0	hSpCas9	negative selection	8057888
237270487	237270510	1	+	27260156	NCIH1373	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.05129992335154465	[840]	[1294,683,846,307]	0	hSpCas9	negative selection	8057889
237374721	237374744	1	+	27260156	NCIH1373	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.5145981531220786	[388]	[372,324,269,414]	5	hSpCas9	negative selection	8057890
237042511	237042534	1	+	27260156	PATU8902	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	1.0090506742221717	[170]	[498,295,671,383]	9	hSpCas9	negative selection	8114885
237042554	237042577	1	-	27260156	PATU8902	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.2236882589557292	[776]	[931,1234,452,1240]	-2	hSpCas9	negative selection	8114886
237374740	237374763	1	-	27260156	PATU8902	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.005136201850538924	[368]	[440,559,289,869]	0	hSpCas9	negative selection	8114887
237270600	237270623	1	-	27260156	PATU8902	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.476475520715387	[557]	[747,1090,1266,1177]	5	hSpCas9	negative selection	8179139
237270487	237270510	1	+	27260156	PATU8902	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.15887375072872512	[840]	[1563,1349,1409,805]	1	hSpCas9	negative selection	8179140
237374721	237374744	1	+	27260156	PATU8902	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.35719654112464566	[388]	[695,755,563,800]	3	hSpCas9	negative selection	8179141
237042511	237042534	1	+	27260156	PANC1	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.44700000187993383	[170]	[133,352,202,148]	7	hSpCas9	negative selection	8236136
237042554	237042577	1	-	27260156	PANC1	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.03239715590832459	[776]	[592,883,665,627]	0	hSpCas9	negative selection	8236137
237374740	237374763	1	-	27260156	PANC1	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.5414796054610028	[368]	[288,580,373,597]	8	hSpCas9	negative selection	8236138
237270600	237270623	1	-	27260156	PANC1	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.1474392483364834	[557]	[285,593,532,359]	-2	hSpCas9	negative selection	8300390
237270487	237270510	1	+	27260156	PANC1	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.08038809490479681	[840]	[989,865,644,585]	1	hSpCas9	negative selection	8300391
237374721	237374744	1	+	27260156	PANC1	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.07590247343527853	[388]	[154,389,543,330]	1	hSpCas9	negative selection	8300392
237042511	237042534	1	+	27260156	PANC0813	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.5285706219096692	[170]	[258,253,301,337]	8	hSpCas9	negative selection	8357387
237042554	237042577	1	-	27260156	PANC0813	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.11114686358374826	[776]	[1025,882,902,1124]	1	hSpCas9	negative selection	8357388
237374740	237374763	1	-	27260156	PANC0813	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.6026550303978688	[368]	[729,969,410,532]	8	hSpCas9	negative selection	8357389
237270600	237270623	1	-	27260156	PANC0813	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.31996045606142787	[557]	[960,852,637,830]	5	hSpCas9	negative selection	8421641
237270487	237270510	1	+	27260156	PANC0813	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.03635694595733918	[840]	[1037,1086,915,824]	0	hSpCas9	negative selection	8421642
237374721	237374744	1	+	27260156	PANC0813	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.16918105532954109	[388]	[378,490,717,457]	2	hSpCas9	negative selection	8421643
237042511	237042534	1	+	27260156	RDES	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.36135697686438384	[170]	[130,90,233,167]	-6	hSpCas9	negative selection	8478638
237042554	237042577	1	-	27260156	RDES	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.168062110985726	[776]	[866,871,1155,1161]	2	hSpCas9	negative selection	8478639
237374740	237374763	1	-	27260156	RDES	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.06460216425136944	[368]	[356,372,578,490]	1	hSpCas9	negative selection	8478640
237270600	237270623	1	-	27260156	RDES	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.14553404647233714	[557]	[541,544,578,658]	-2	hSpCas9	negative selection	8542892
237270487	237270510	1	+	27260156	RDES	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.5141606076119628	[840]	[583,604,712,838]	-7	hSpCas9	negative selection	8542893
237374721	237374744	1	+	27260156	RDES	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.2592908929373622	[388]	[274,357,381,513]	-4	hSpCas9	negative selection	8542894
237042511	237042534	1	+	27260156	PC3	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.2584453795220325	[170]	[171,178,338,165]	5	hSpCas9	negative selection	8599889
237042554	237042577	1	-	27260156	PC3	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.26397102184744603	[776]	[399,635,995,733]	-5	hSpCas9	negative selection	8599890
237374740	237374763	1	-	27260156	PC3	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.39705225024939994	[368]	[286,481,1090,349]	8	hSpCas9	negative selection	8599891
237270600	237270623	1	-	27260156	PC3	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.3763684490334601	[557]	[487,556,1354,774]	7	hSpCas9	negative selection	8664143
237270487	237270510	1	+	27260156	PC3	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.05475815739219059	[840]	[634,620,1648,904]	1	hSpCas9	negative selection	8664144
237374721	237374744	1	+	27260156	PC3	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.017986578650819263	[388]	[245,313,860,320]	0	hSpCas9	negative selection	8664145
237042511	237042534	1	+	27260156	PATU8988T	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.27318694620839556	[170]	[123,203,77,148]	-4	hSpCas9	negative selection	8721140
237042554	237042577	1	-	27260156	PATU8988T	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.1058257781429891	[776]	[623,1075,725,833]	1	hSpCas9	negative selection	8721141
237374740	237374763	1	-	27260156	PATU8988T	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.601061424987008	[368]	[672,619,285,599]	8	hSpCas9	negative selection	8721142
237270600	237270623	1	-	27260156	PATU8988T	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.03298564285387284	[557]	[635,452,461,552]	0	hSpCas9	negative selection	8785394
237270487	237270510	1	+	27260156	PATU8988T	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.1497150886750238	[840]	[1228,809,725,828]	2	hSpCas9	negative selection	8785395
237374721	237374744	1	+	27260156	PATU8988T	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.2327158281265036	[388]	[520,478,297,476]	4	hSpCas9	negative selection	8785396
237042511	237042534	1	+	27260156	T47D	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.1430753398408937	[170]	[253,176,202,250]	3	hSpCas9	negative selection	8842391
237042554	237042577	1	-	27260156	T47D	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.11708796976953784	[776]	[986,949,946,1047]	2	hSpCas9	negative selection	8842392
237374740	237374763	1	-	27260156	T47D	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.23047902710796025	[368]	[470,514,419,614]	5	hSpCas9	negative selection	8842393
237270600	237270623	1	-	27260156	T47D	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.21128129424771128	[557]	[749,633,787,850]	4	hSpCas9	negative selection	8906645
237270487	237270510	1	+	27260156	T47D	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.2076460825380292	[840]	[864,646,861,1042]	-4	hSpCas9	negative selection	8906646
237374721	237374744	1	+	27260156	T47D	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.21927267922321753	[388]	[387,313,394,468]	-5	hSpCas9	negative selection	8906647
237042511	237042534	1	+	27260156	SU8686	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.20139572497204594	[170]	[156,148,291,192]	3	hSpCas9	negative selection	8963642
237042554	237042577	1	-	27260156	SU8686	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	0.2673463666574565	[776]	[820,904,791,1246]	4	hSpCas9	negative selection	8963643
237374740	237374763	1	-	27260156	SU8686	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.5009428471521873	[368]	[476,492,444,684]	8	hSpCas9	negative selection	8963644
237270600	237270623	1	-	27260156	SU8686	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.3763974999982216	[557]	[710,605,684,910]	6	hSpCas9	negative selection	9027896
237270487	237270510	1	+	27260156	SU8686	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.11344674195647575	[840]	[768,840,1139,876]	2	hSpCas9	negative selection	9027897
237374721	237374744	1	+	27260156	SU8686	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.0410812823976755	[388]	[328,340,493,445]	0	hSpCas9	negative selection	9027898
237042511	237042534	1	+	27260156	SKES1	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.3019619500161548	[170]	[164,173,127,97]	-6	hSpCas9	negative selection	9084893
237042554	237042577	1	-	27260156	SKES1	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.2760874256331479	[776]	[636,895,580,488]	-6	hSpCas9	negative selection	9084894
237374740	237374763	1	-	27260156	SKES1	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.07427763642038909	[368]	[376,349,457,226]	-2	hSpCas9	negative selection	9084895
237270600	237270623	1	-	27260156	SKES1	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.09521456840044054	[557]	[622,701,516,552]	2	hSpCas9	negative selection	9149147
237270487	237270510	1	+	27260156	SKES1	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.13544169174261	[840]	[784,801,847,633]	-3	hSpCas9	negative selection	9149148
237374721	237374744	1	+	27260156	SKES1	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.0006516607144358977	[388]	[453,424,342,345]	0	hSpCas9	negative selection	9149149
237042511	237042534	1	+	27260156	TOV112D	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.21220845298735158	[170]	[322,158,146,165]	4	hSpCas9	negative selection	9206144
237042554	237042577	1	-	27260156	TOV112D	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.09102633959054596	[776]	[916,786,521,724]	-2	hSpCas9	negative selection	9206145
237374740	237374763	1	-	27260156	TOV112D	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.030268961724097543	[368]	[420,562,292,283]	0	hSpCas9	negative selection	9206146
237270600	237270623	1	-	27260156	TOV112D	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.48431037545756284	[557]	[713,1379,665,514]	8	hSpCas9	negative selection	9270398
237270487	237270510	1	+	27260156	TOV112D	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.04069966637661704	[840]	[770,698,1007,934]	0	hSpCas9	negative selection	9270399
237374721	237374744	1	+	27260156	TOV112D	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	0.11876991253801239	[388]	[402,390,360,523]	2	hSpCas9	negative selection	9270400
237042511	237042534	1	+	27260156	TC71	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	0.07682560448191711	[170]	[126,132,214,305]	2	hSpCas9	negative selection	9327395
237042554	237042577	1	-	27260156	TC71	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.35338293908530244	[776]	[598,670,663,675]	-7	hSpCas9	negative selection	9327396
237374740	237374763	1	-	27260156	TC71	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	0.3713729403982775	[368]	[581,519,459,482]	8	hSpCas9	negative selection	9327397
237270600	237270623	1	-	27260156	TC71	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	0.28474340295870004	[557]	[677,632,751,859]	7	hSpCas9	negative selection	9391649
237270487	237270510	1	+	27260156	TC71	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	0.10293031043940404	[840]	[921,960,810,1198]	2	hSpCas9	negative selection	9391650
237374721	237374744	1	+	27260156	TC71	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.21625206508786599	[388]	[397,296,341,400]	-5	hSpCas9	negative selection	9391651
237042511	237042534	1	+	27260156	TC32	viability	GGCGCGGAACCATGGCCGATGGG	RYR2	ENSG00000198626	-0.7721009649327348	[170]	[94,59,132,102]	-9	hSpCas9	negative selection	9448646
237042554	237042577	1	-	27260156	TC32	viability	CGCTTACAGTTCGCAGGAACTGG	RYR2	ENSG00000198626	-0.4618649783082812	[776]	[520,298,717,682]	-7	hSpCas9	negative selection	9448647
237374740	237374763	1	-	27260156	TC32	viability	CCAGCTTATCAGTTGAAGACCGG	RYR2	ENSG00000198626	-0.552901279316236	[368]	[184,118,334,369]	-8	hSpCas9	negative selection	9448648
237270600	237270623	1	-	27260156	TC32	viability	TCCCACCTTGGAATTGGAAGTGG	RYR2	ENSG00000198626	-0.2537252044514997	[557]	[344,321,597,559]	-4	hSpCas9	negative selection	9512900
237270487	237270510	1	+	27260156	TC32	viability	CCCTTTGCAGGATGATGAAGTGG	RYR2	ENSG00000198626	-0.5519940225675647	[840]	[537,417,641,591]	-8	hSpCas9	negative selection	9512901
237374721	237374744	1	+	27260156	TC32	viability	TGTGCTGCCTGTCCACCTCCCGG	RYR2	ENSG00000198626	-0.021487540022436857	[388]	[302,330,414,398]	0	hSpCas9	negative selection	9512902
237042510	237042533	1	+	27869803	HPAFII	viability after 27 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.18298399751623085	[190]	[64,107,NaN]	-1	hSpCas9	negative selection	9532859
237270548	237270571	1	+	27869803	HPAFII	viability after 27 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.3401412233623348	[158]	[77,128,NaN]	2	hSpCas9	negative selection	9532862
237330924	237330947	1	-	27869803	HPAFII	viability after 27 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.17552297228120906	[488]	[297,168,NaN]	-1	hSpCas9	negative selection	9532865
237369590	237369613	1	-	27869803	HPAFII	viability after 27 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.509115775528063	[446]	[328,338,NaN]	4	hSpCas9	negative selection	9532867
237374728	237374751	1	-	27869803	HPAFII	viability after 27 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.01048799882604734	[228]	[69,163,NaN]	0	hSpCas9	negative selection	9532868
237377352	237377375	1	+	27869803	HPAFII	viability after 27 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9532869
237042510	237042533	1	+	27869803	HPAFII	viability after 15 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	0.262923519036764	[190]	[167,294,NaN]	3	hSpCas9	negative selection	9615308
237270548	237270571	1	+	27869803	HPAFII	viability after 15 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.18789569978968546	[158]	[214,181,NaN]	2	hSpCas9	negative selection	9615311
237330924	237330947	1	-	27869803	HPAFII	viability after 15 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.11208166802288677	[488]	[587,422,NaN]	-1	hSpCas9	negative selection	9615314
237369590	237369613	1	-	27869803	HPAFII	viability after 15 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.20483146855847256	[446]	[631,504,NaN]	2	hSpCas9	negative selection	9615316
237374728	237374751	1	-	27869803	HPAFII	viability after 15 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.33736484273567047	[228]	[142,226,NaN]	-4	hSpCas9	negative selection	9615317
237377352	237377375	1	+	27869803	HPAFII	viability after 15 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9615318
237042510	237042533	1	+	27869803	ASPC1	viability after 36 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	1.1023697616012786	[403]	[430,188,299]	9	hSpCas9	negative selection	9697757
237270548	237270571	1	+	27869803	ASPC1	viability after 36 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.7078572565162874	[338]	[190,308,100]	7	hSpCas9	negative selection	9697760
237330924	237330947	1	-	27869803	ASPC1	viability after 36 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.42710694428294504	[974]	[204,391,173]	-4	hSpCas9	negative selection	9697763
237369590	237369613	1	-	27869803	ASPC1	viability after 36 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.2740909614654874	[909]	[337,589,248]	2	hSpCas9	negative selection	9697765
237374728	237374751	1	-	27869803	ASPC1	viability after 36 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.8522101794509239	[739]	[428,519,444]	7	hSpCas9	negative selection	9697766
237377352	237377375	1	+	27869803	ASPC1	viability after 36 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.5960704242760739	[69]	[56,0,50]	6	hSpCas9	negative selection	9697767
237042510	237042533	1	+	27869803	PATU8988S	viability after 35 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	1.3304729122519543	[398]	[460,346,NaN]	9	hSpCas9	negative selection	9780206
237270548	237270571	1	+	27869803	PATU8988S	viability after 35 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.6100891375357688	[277]	[125,215,NaN]	6	hSpCas9	negative selection	9780209
237330924	237330947	1	-	27869803	PATU8988S	viability after 35 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.3691529726410576	[954]	[619,372,NaN]	4	hSpCas9	negative selection	9780212
237369590	237369613	1	-	27869803	PATU8988S	viability after 35 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.2802431655312918	[914]	[458,435,NaN]	3	hSpCas9	negative selection	9780214
237374728	237374751	1	-	27869803	PATU8988S	viability after 35 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.5165785262065481	[778]	[372,524,NaN]	6	hSpCas9	negative selection	9780215
237377352	237377375	1	+	27869803	PATU8988S	viability after 35 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	1.2637987853868191	[47]	[11,80,NaN]	9	hSpCas9	negative selection	9780216
237042510	237042533	1	+	27869803	PATU8988S	viability after 31 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	1.0271219607125497	[398]	[303,349,NaN]	9	hSpCas9	negative selection	9862655
237270548	237270571	1	+	27869803	PATU8988S	viability after 31 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.3782460372867704	[277]	[140,147,NaN]	4	hSpCas9	negative selection	9862658
237330924	237330947	1	-	27869803	PATU8988S	viability after 31 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	0.5262761563784792	[954]	[503,604,NaN]	6	hSpCas9	negative selection	9862661
237369590	237369613	1	-	27869803	PATU8988S	viability after 31 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.28736800038852817	[914]	[384,521,NaN]	3	hSpCas9	negative selection	9862663
237374728	237374751	1	-	27869803	PATU8988S	viability after 31 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.5307357542766766	[778]	[369,548,NaN]	6	hSpCas9	negative selection	9862664
237377352	237377375	1	+	27869803	PATU8988S	viability after 31 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	-0.40673210594483633	[47]	[2,28,NaN]	-4	hSpCas9	negative selection	9862665
237042510	237042533	1	+	27869803	HPAFII	viability after 35 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-1.009308979325791	[190]	[0,100,NaN]	-5	hSpCas9	negative selection	9945104
237270548	237270571	1	+	27869803	HPAFII	viability after 35 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.057580299648091415	[158]	[95,69,NaN]	0	hSpCas9	negative selection	9945107
237330924	237330947	1	-	27869803	HPAFII	viability after 35 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.03295095120924896	[488]	[288,188,NaN]	0	hSpCas9	negative selection	9945110
237369590	237369613	1	-	27869803	HPAFII	viability after 35 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.9932712078879086	[446]	[465,432,NaN]	6	hSpCas9	negative selection	9945112
237374728	237374751	1	-	27869803	HPAFII	viability after 35 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	0.6133547537691285	[228]	[55,313,NaN]	4	hSpCas9	negative selection	9945113
237377352	237377375	1	+	27869803	HPAFII	viability after 35 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	9945114
237042510	237042533	1	+	27869803	HPAFII	viability after 31 days	AGGCGCGGAACCATGGCCGATGG	RYR2	ENSG00000198626	-0.15909512763933475	[190]	[28,168,NaN]	-1	hSpCas9	negative selection	10027553
237270548	237270571	1	+	27869803	HPAFII	viability after 31 days	AAGCTATGCTTGGCAGCAGAAGG	RYR2	ENSG00000198626	0.40975316931758643	[158]	[85,153,NaN]	3	hSpCas9	negative selection	10027556
237330924	237330947	1	-	27869803	HPAFII	viability after 31 days	CTGCAGCGCCCGGACAGAGAGGG	RYR2	ENSG00000198626	-0.4326503107126266	[488]	[232,170,NaN]	-3	hSpCas9	negative selection	10027559
237369590	237369613	1	-	27869803	HPAFII	viability after 31 days	TCACCATGCCACTATAGGAATGG	RYR2	ENSG00000198626	0.7481888626407914	[446]	[384,460,NaN]	5	hSpCas9	negative selection	10027561
237374728	237374751	1	-	27869803	HPAFII	viability after 31 days	TTGAAGACCGGGAGGTGGACAGG	RYR2	ENSG00000198626	-0.031254111868182305	[228]	[86,167,NaN]	0	hSpCas9	negative selection	10027562
237377352	237377375	1	+	27869803	HPAFII	viability after 31 days	GCCTCTAAGCAGCGATCAGAAGG	RYR2	ENSG00000198626	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10027563
237388162	237388185	1	+	28162770	P31FUJ	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-1.0708347247509857	[201]	[112]	-6	hSpCas9	negative selection	10229219
237548546	237548569	1	+	28162770	P31FUJ	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.7361263496526156	[351]	[688]	8	hSpCas9	negative selection	10229220
237550565	237550588	1	-	28162770	P31FUJ	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	1.3041131218996687	[172]	[501]	9	hSpCas9	negative selection	10229221
237639155	237639178	1	-	28162770	P31FUJ	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-0.9208581980996384	[28]	[17]	-6	hSpCas9	negative selection	10229222
237707004	237707027	1	+	28162770	P31FUJ	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.2526246227558633	[44]	[62]	2	hSpCas9	negative selection	10229223
237783847	237783870	1	+	28162770	P31FUJ	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.4864613880183687	[163]	[269]	5	hSpCas9	negative selection	10229224
237784131	237784154	1	+	28162770	P31FUJ	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.7464392354188242	[174]	[344]	8	hSpCas9	negative selection	10229225
237330946	237330969	1	+	28162770	P31FUJ	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.22662941422291868	[183]	[252]	2	hSpCas9	negative selection	10229226
237492986	237493009	1	-	28162770	P31FUJ	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.788542697983976	[737]	[1497]	8	hSpCas9	negative selection	10229227
237496683	237496706	1	+	28162770	P31FUJ	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.03157486791082531	[357]	[429]	0	hSpCas9	negative selection	10229228
237388162	237388185	1	+	28162770	TF1	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10398585
237548546	237548569	1	+	28162770	TF1	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10398586
237550565	237550588	1	-	28162770	TF1	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10398587
237639155	237639178	1	-	28162770	TF1	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10398588
237707004	237707027	1	+	28162770	TF1	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10398589
237783847	237783870	1	+	28162770	TF1	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10398590
237784131	237784154	1	+	28162770	TF1	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10398591
237330946	237330969	1	+	28162770	TF1	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10398592
237492986	237493009	1	-	28162770	TF1	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	NaN	[NaN]	[647]	1	hSpCas9	negative selection	10398593
237496683	237496706	1	+	28162770	TF1	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10398594
237388162	237388185	1	+	28162770	SKM1	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.4510167963844105	[47]	[115]	4	hSpCas9	negative selection	10567951
237548546	237548569	1	+	28162770	SKM1	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.2422194364065296	[92]	[138]	-2	hSpCas9	negative selection	10567952
237550565	237550588	1	-	28162770	SKM1	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.00807330053568206	[62]	[111]	0	hSpCas9	negative selection	10567953
237639155	237639178	1	-	28162770	SKM1	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-2.558967292188212	[9]	[2]	-9	hSpCas9	negative selection	10567954
237707004	237707027	1	+	28162770	SKM1	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.2849135058945065	[12]	[27]	2	hSpCas9	negative selection	10567955
237783847	237783870	1	+	28162770	SKM1	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.5952308361749832	[46]	[54]	-5	hSpCas9	negative selection	10567956
237784131	237784154	1	+	28162770	SKM1	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10567957
237330946	237330969	1	+	28162770	SKM1	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.05246741989413556	[47]	[87]	0	hSpCas9	negative selection	10567958
237492986	237493009	1	-	28162770	SKM1	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.32025088493575193	[192]	[425]	3	hSpCas9	negative selection	10567959
237496683	237496706	1	+	28162770	SKM1	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-1.1092836501024768	[71]	[58]	-7	hSpCas9	negative selection	10567960
237388162	237388185	1	+	28162770	SKM1	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.4510167963844105	[47]	[115]	4	hSpCas9	negative selection	10737317
237548546	237548569	1	+	28162770	SKM1	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.2422194364065296	[92]	[138]	-2	hSpCas9	negative selection	10737318
237550565	237550588	1	-	28162770	SKM1	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.00807330053568206	[62]	[111]	0	hSpCas9	negative selection	10737319
237639155	237639178	1	-	28162770	SKM1	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-2.558967292188212	[9]	[2]	-9	hSpCas9	negative selection	10737320
237707004	237707027	1	+	28162770	SKM1	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.2849135058945065	[12]	[27]	2	hSpCas9	negative selection	10737321
237783847	237783870	1	+	28162770	SKM1	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.5952308361749832	[46]	[54]	-5	hSpCas9	negative selection	10737322
237784131	237784154	1	+	28162770	SKM1	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10737323
237330946	237330969	1	+	28162770	SKM1	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.05246741989413556	[47]	[87]	0	hSpCas9	negative selection	10737324
237492986	237493009	1	-	28162770	SKM1	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.32025088493575193	[192]	[425]	3	hSpCas9	negative selection	10737325
237496683	237496706	1	+	28162770	SKM1	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-1.1092836501024768	[71]	[58]	-7	hSpCas9	negative selection	10737326
237388162	237388185	1	+	28162770	PL21	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.23281979278678608	[188]	[69]	-2	hSpCas9	negative selection	10906683
237548546	237548569	1	+	28162770	PL21	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.3648129255003417	[357]	[120]	-3	hSpCas9	negative selection	10906684
237550565	237550588	1	-	28162770	PL21	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	1.4349691390639907	[197]	[232]	9	hSpCas9	negative selection	10906685
237639155	237639178	1	-	28162770	PL21	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-3.3848228862318366	[23]	[0]	-9	hSpCas9	negative selection	10906686
237707004	237707027	1	+	28162770	PL21	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	1.2781421264905934	[53]	[56]	9	hSpCas9	negative selection	10906687
237783847	237783870	1	+	28162770	PL21	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.8587540745642483	[174]	[41]	-5	hSpCas9	negative selection	10906688
237784131	237784154	1	+	28162770	PL21	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-0.3303751022094596	[155]	[53]	-2	hSpCas9	negative selection	10906689
237330946	237330969	1	+	28162770	PL21	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	-0.5559348026245907	[151]	[44]	-4	hSpCas9	negative selection	10906690
237492986	237493009	1	-	28162770	PL21	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.5030300091372273	[594]	[366]	4	hSpCas9	negative selection	10906691
237496683	237496706	1	+	28162770	PL21	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.05649702014632302	[269]	[112]	0	hSpCas9	negative selection	10906692
237388162	237388185	1	+	28162770	P31FUJ	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-1.0708347247509857	[201]	[112]	-6	hSpCas9	negative selection	11076049
237548546	237548569	1	+	28162770	P31FUJ	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.7361263496526156	[351]	[688]	8	hSpCas9	negative selection	11076050
237550565	237550588	1	-	28162770	P31FUJ	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	1.3041131218996687	[172]	[501]	9	hSpCas9	negative selection	11076051
237639155	237639178	1	-	28162770	P31FUJ	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-0.9208581980996384	[28]	[17]	-6	hSpCas9	negative selection	11076052
237707004	237707027	1	+	28162770	P31FUJ	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.2526246227558633	[44]	[62]	2	hSpCas9	negative selection	11076053
237783847	237783870	1	+	28162770	P31FUJ	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.4864613880183687	[163]	[269]	5	hSpCas9	negative selection	11076054
237784131	237784154	1	+	28162770	P31FUJ	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.7464392354188242	[174]	[344]	8	hSpCas9	negative selection	11076055
237330946	237330969	1	+	28162770	P31FUJ	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.22662941422291868	[183]	[252]	2	hSpCas9	negative selection	11076056
237492986	237493009	1	-	28162770	P31FUJ	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.788542697983976	[737]	[1497]	8	hSpCas9	negative selection	11076057
237496683	237496706	1	+	28162770	P31FUJ	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.03157486791082531	[357]	[429]	0	hSpCas9	negative selection	11076058
237388162	237388185	1	+	28162770	OCIAML5	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.18648560993455626	[115]	[183]	-1	hSpCas9	negative selection	11245415
237548546	237548569	1	+	28162770	OCIAML5	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.4083115626561947	[285]	[388]	-3	hSpCas9	negative selection	11245416
237550565	237550588	1	-	28162770	OCIAML5	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	-0.1454255135545886	[124]	[203]	-1	hSpCas9	negative selection	11245417
237639155	237639178	1	-	28162770	OCIAML5	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-2.640562465670285	[37]	[10]	-8	hSpCas9	negative selection	11245418
237707004	237707027	1	+	28162770	OCIAML5	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.8772858391923342	[18]	[62]	7	hSpCas9	negative selection	11245419
237783847	237783870	1	+	28162770	OCIAML5	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	1.8667516765919496	[35]	[236]	9	hSpCas9	negative selection	11245420
237784131	237784154	1	+	28162770	OCIAML5	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-0.41425776392649494	[109]	[148]	-3	hSpCas9	negative selection	11245421
237330946	237330969	1	+	28162770	OCIAML5	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.35383772768388194	[87]	[202]	3	hSpCas9	negative selection	11245422
237492986	237493009	1	-	28162770	OCIAML5	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.6674860402108713	[375]	[1077]	6	hSpCas9	negative selection	11245423
237496683	237496706	1	+	28162770	OCIAML5	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.3273812046968222	[150]	[341]	2	hSpCas9	negative selection	11245424
237388162	237388185	1	+	28162770	EOL1	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	1.1215846186300882	[245]	[281]	8	hSpCas9	negative selection	11414781
237548546	237548569	1	+	28162770	EOL1	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.5562809620163025	[434]	[336]	5	hSpCas9	negative selection	11414782
237550565	237550588	1	-	28162770	EOL1	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.07381330244675377	[421]	[233]	0	hSpCas9	negative selection	11414783
237639155	237639178	1	-	28162770	EOL1	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-0.21841018227150855	[52]	[23]	-2	hSpCas9	negative selection	11414784
237707004	237707027	1	+	28162770	EOL1	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	-0.22892670909118373	[108]	[48]	-2	hSpCas9	negative selection	11414785
237783847	237783870	1	+	28162770	EOL1	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.7513281922157888	[273]	[242]	6	hSpCas9	negative selection	11414786
237784131	237784154	1	+	28162770	EOL1	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-0.5150753659865823	[216]	[79]	-4	hSpCas9	negative selection	11414787
237330946	237330969	1	+	28162770	EOL1	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	1.12771072142693	[204]	[235]	8	hSpCas9	negative selection	11414788
237492986	237493009	1	-	28162770	EOL1	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.9473447815483533	[878]	[892]	7	hSpCas9	negative selection	11414789
237496683	237496706	1	+	28162770	EOL1	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.7130436663768228	[329]	[284]	6	hSpCas9	negative selection	11414790
237388162	237388185	1	+	28162770	MOLM13	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	1.0797275882571298	[194]	[297]	7	hSpCas9	negative selection	11584147
237548546	237548569	1	+	28162770	MOLM13	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.34213038735005563	[574]	[526]	2	hSpCas9	negative selection	11584148
237550565	237550588	1	-	28162770	MOLM13	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.08297187064207046	[315]	[241]	0	hSpCas9	negative selection	11584149
237639155	237639178	1	-	28162770	MOLM13	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-1.741563984084371	[73]	[15]	-7	hSpCas9	negative selection	11584150
237707004	237707027	1	+	28162770	MOLM13	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	-0.4853164069764804	[90]	[46]	-3	hSpCas9	negative selection	11584151
237783847	237783870	1	+	28162770	MOLM13	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.1873253152736713	[262]	[166]	-1	hSpCas9	negative selection	11584152
237784131	237784154	1	+	28162770	MOLM13	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.30816569295308077	[228]	[204]	2	hSpCas9	negative selection	11584153
237330946	237330969	1	+	28162770	MOLM13	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.7388507031500016	[241]	[291]	5	hSpCas9	negative selection	11584154
237492986	237493009	1	-	28162770	MOLM13	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.4033605866304395	[822]	[786]	3	hSpCas9	negative selection	11584155
237496683	237496706	1	+	28162770	MOLM13	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.1630348000161579	[377]	[305]	1	hSpCas9	negative selection	11584156
237388162	237388185	1	+	28162770	HEL	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.527261614580421	[181]	[167]	4	hSpCas9	negative selection	11753513
237548546	237548569	1	+	28162770	HEL	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.2634513576707149	[371]	[285]	2	hSpCas9	negative selection	11753514
237550565	237550588	1	-	28162770	HEL	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.10508204605755733	[314]	[216]	0	hSpCas9	negative selection	11753515
237639155	237639178	1	-	28162770	HEL	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-3.654941716640328	[58]	[2]	-9	hSpCas9	negative selection	11753516
237707004	237707027	1	+	28162770	HEL	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.7148886177561923	[77]	[81]	6	hSpCas9	negative selection	11753517
237783847	237783870	1	+	28162770	HEL	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.4441931526182768	[209]	[182]	4	hSpCas9	negative selection	11753518
237784131	237784154	1	+	28162770	HEL	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	1.0346186102919486	[156]	[205]	8	hSpCas9	negative selection	11753519
237330946	237330969	1	+	28162770	HEL	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.04905911417809178	[165]	[109]	0	hSpCas9	negative selection	11753520
237492986	237493009	1	-	28162770	HEL	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.4670010897629464	[714]	[632]	4	hSpCas9	negative selection	11753521
237496683	237496706	1	+	28162770	HEL	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.399352501488676	[312]	[151]	-3	hSpCas9	negative selection	11753522
237388162	237388185	1	+	28162770	MV411	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.32621466416689227	[195]	[206]	3	hSpCas9	negative selection	11922879
237548546	237548569	1	+	28162770	MV411	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.22457344243103838	[317]	[312]	2	hSpCas9	negative selection	11922880
237550565	237550588	1	-	28162770	MV411	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	1.1847017954348127	[187]	[359]	9	hSpCas9	negative selection	11922881
237639155	237639178	1	-	28162770	MV411	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-1.0420690664122092	[43]	[17]	-6	hSpCas9	negative selection	11922882
237707004	237707027	1	+	28162770	MV411	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	1.1702696902603154	[47]	[90]	9	hSpCas9	negative selection	11922883
237783847	237783870	1	+	28162770	MV411	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.1175572682358656	[150]	[137]	1	hSpCas9	negative selection	11922884
237784131	237784154	1	+	28162770	MV411	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	0.6269309332039521	[112]	[146]	5	hSpCas9	negative selection	11922885
237330946	237330969	1	+	28162770	MV411	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.10899078081363084	[152]	[138]	0	hSpCas9	negative selection	11922886
237492986	237493009	1	-	28162770	MV411	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.684424022895264	[635]	[860]	6	hSpCas9	negative selection	11922887
237496683	237496706	1	+	28162770	MV411	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.42668716981319943	[291]	[182]	-3	hSpCas9	negative selection	11922888
237388162	237388185	1	+	28162770	MONOMAC1	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.48654346425453854	[153]	[125]	-4	hSpCas9	negative selection	12092245
237548546	237548569	1	+	28162770	MONOMAC1	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.4793486814251974	[213]	[341]	5	hSpCas9	negative selection	12092246
237550565	237550588	1	-	28162770	MONOMAC1	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.63064760407314	[150]	[267]	6	hSpCas9	negative selection	12092247
237639155	237639178	1	-	28162770	MONOMAC1	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-1.2443425618379103	[30]	[14]	-7	hSpCas9	negative selection	12092248
237707004	237707027	1	+	28162770	MONOMAC1	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	-0.600392541290762	[40]	[30]	-5	hSpCas9	negative selection	12092249
237783847	237783870	1	+	28162770	MONOMAC1	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	0.640233652902338	[149]	[267]	6	hSpCas9	negative selection	12092250
237784131	237784154	1	+	28162770	MONOMAC1	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-0.8470943760025947	[101]	[64]	-6	hSpCas9	negative selection	12092251
237330946	237330969	1	+	28162770	MONOMAC1	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	1.1209332342591254	[72]	[181]	8	hSpCas9	negative selection	12092252
237492986	237493009	1	-	28162770	MONOMAC1	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.6658442965813756	[374]	[681]	6	hSpCas9	negative selection	12092253
237496683	237496706	1	+	28162770	MONOMAC1	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.1785405034421644	[154]	[156]	-1	hSpCas9	negative selection	12092254
237388162	237388185	1	+	28162770	OCIAML2	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	-0.44893475414284223	[32]	[133]	-4	hSpCas9	negative selection	12261611
237548546	237548569	1	+	28162770	OCIAML2	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	-0.008628846992730699	[50]	[280]	0	hSpCas9	negative selection	12261612
237550565	237550588	1	-	28162770	OCIAML2	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	0.04462370366759061	[52]	[302]	0	hSpCas9	negative selection	12261613
237639155	237639178	1	-	28162770	OCIAML2	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-1.0921182019884315	[4]	[12]	-6	hSpCas9	negative selection	12261614
237707004	237707027	1	+	28162770	OCIAML2	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.26633576892404487	[11]	[79]	2	hSpCas9	negative selection	12261615
237783847	237783870	1	+	28162770	OCIAML2	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-0.733664231075955	[32]	[109]	-5	hSpCas9	negative selection	12261616
237784131	237784154	1	+	28162770	OCIAML2	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-1.392627313240888	[26]	[56]	-7	hSpCas9	negative selection	12261617
237330946	237330969	1	+	28162770	OCIAML2	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.5790009424824393	[24]	[206]	5	hSpCas9	negative selection	12261618
237492986	237493009	1	-	28162770	OCIAML2	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.44919982607385567	[110]	[839]	4	hSpCas9	negative selection	12261619
237496683	237496706	1	+	28162770	OCIAML2	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	-0.9064258846878025	[69]	[206]	-6	hSpCas9	negative selection	12261620
237388162	237388185	1	+	28162770	OCIAML3	viability	AACATGGTGAAGAGCAGCGGAGG	RYR2	ENSG00000198626	0.720307270453324	[37]	[188]	6	hSpCas9	negative selection	12430977
237548546	237548569	1	+	28162770	OCIAML3	viability	GCGCGGGATCGAATCCGGCAGGG	RYR2	ENSG00000198626	0.17404563162613995	[100]	[343]	1	hSpCas9	negative selection	12430978
237550565	237550588	1	-	28162770	OCIAML3	viability	AGAGTGTAGGGAACAAGGCGAGG	RYR2	ENSG00000198626	-0.1997287012121168	[69]	[183]	-1	hSpCas9	negative selection	12430979
237639155	237639178	1	-	28162770	OCIAML3	viability	GGTGAGGGACCATCTCGGGAAGG	RYR2	ENSG00000198626	-4.17897014104532	[17]	[2]	-9	hSpCas9	negative selection	12430980
237707004	237707027	1	+	28162770	OCIAML3	viability	GAAACTCATGGAAGAAATCGTGG	RYR2	ENSG00000198626	0.3570827591948904	[14]	[57]	3	hSpCas9	negative selection	12430981
237783847	237783870	1	+	28162770	OCIAML3	viability	GAGGGACTTCCACAAAGCGATGG	RYR2	ENSG00000198626	-1.112880950587547	[47]	[66]	-7	hSpCas9	negative selection	12430982
237784131	237784154	1	+	28162770	OCIAML3	viability	GAAGCGCCAAACGCATCGAGAGG	RYR2	ENSG00000198626	-1.1376293456644198	[42]	[58]	-7	hSpCas9	negative selection	12430983
237330946	237330969	1	+	28162770	OCIAML3	viability	GGAGATGCTGGCTAACACCGTGG	RYR2	ENSG00000198626	0.07112520908097641	[34]	[110]	0	hSpCas9	negative selection	12430984
237492986	237493009	1	-	28162770	OCIAML3	viability	TAGAACGGACTGCAACCCCGTGG	RYR2	ENSG00000198626	0.5667805665460262	[175]	[786]	5	hSpCas9	negative selection	12430985
237496683	237496706	1	+	28162770	OCIAML3	viability	GAGTGGGGTGGAAATGGTGTTGG	RYR2	ENSG00000198626	0.1409803044016007	[72]	[242]	1	hSpCas9	negative selection	12430986