Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5929
• Symbol: Rbbp5
• Description: RB binding protein 5, histone lysine methyltransferase complex subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/Rbbp5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
205096801	205096824	1	+	26472758	Jiyoye	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.020973033263909	[478]	[88]	-8	hSpCas9	negative selection	134152
205103937	205103960	1	-	26472758	Jiyoye	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.6385009276123295	[22]	[26]	4	hSpCas9	negative selection	134153
205096764	205096787	1	-	26472758	Jiyoye	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.27563444261342734	[121]	[75]	-2	hSpCas9	negative selection	134154
205100015	205100038	1	-	26472758	Jiyoye	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-2.042857539129174	[152]	[27]	-8	hSpCas9	negative selection	134155
205115857	205115880	1	-	26472758	Jiyoye	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.7221076354390927	[384]	[43]	-9	hSpCas9	negative selection	134156
205114902	205114925	1	-	26472758	Jiyoye	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.4843001617159576	[255]	[137]	-3	hSpCas9	negative selection	134157
205103891	205103914	1	-	26472758	Jiyoye	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.09009125884982516	[222]	[178]	0	hSpCas9	negative selection	134158
205101599	205101622	1	-	26472758	Jiyoye	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-1.3209817550430734	[380]	[114]	-7	hSpCas9	negative selection	134159
205105108	205105131	1	-	26472758	Jiyoye	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-4.792496963330491	[146]	[3]	-9	hSpCas9	negative selection	134160
205105078	205105101	1	-	26472758	Jiyoye	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-5.8022779841230765	[73]	[0]	-9	hSpCas9	negative selection	134161
205096801	205096824	1	+	26472758	KBM7	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.0020113877329564	[1530,803]	[173,96]	-8	hSpCas9	negative selection	325270
205103937	205103960	1	-	26472758	KBM7	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.8837781421773729	[383,208]	[70,75]	-6	hSpCas9	negative selection	325271
205096764	205096787	1	-	26472758	KBM7	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.5742527285050318	[572,595]	[216,157]	-5	hSpCas9	negative selection	325272
205100015	205100038	1	-	26472758	KBM7	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-2.197814811117362	[693,500]	[78,43]	-8	hSpCas9	negative selection	325273
205115857	205115880	1	-	26472758	KBM7	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.0712406504023795	[1238,701]	[76,131]	-8	hSpCas9	negative selection	325274
205114902	205114925	1	-	26472758	KBM7	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.148626263218677	[769,628]	[473,262]	1	hSpCas9	negative selection	325275
205103891	205103914	1	-	26472758	KBM7	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.6425940698616776	[787,594]	[279,701]	7	hSpCas9	negative selection	325276
205101599	205101622	1	-	26472758	KBM7	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-1.0795538735672612	[930,756]	[229,147]	-7	hSpCas9	negative selection	325277
205105108	205105131	1	-	26472758	KBM7	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-0.956855340630303	[292,249]	[73,57]	-6	hSpCas9	negative selection	325278
205105078	205105101	1	-	26472758	KBM7	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.4594252001422414	[114,160]	[21,25]	-7	hSpCas9	negative selection	325279
205096801	205096824	1	+	26472758	Raji	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.8842042248102002	[683]	[42]	-8	hSpCas9	negative selection	516388
205103937	205103960	1	-	26472758	Raji	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.07421667143840022	[175]	[42]	0	hSpCas9	negative selection	516389
205096764	205096787	1	-	26472758	Raji	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.20938285439798418	[278]	[55]	-2	hSpCas9	negative selection	516390
205100015	205100038	1	-	26472758	Raji	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-2.477578965347557	[335]	[13]	-9	hSpCas9	negative selection	516391
205115857	205115880	1	-	26472758	Raji	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.7995070602349195	[479]	[15]	-9	hSpCas9	negative selection	516392
205114902	205114925	1	-	26472758	Raji	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.1363193922082606	[340]	[35]	-7	hSpCas9	negative selection	516393
205103891	205103914	1	-	26472758	Raji	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	-0.6143153021392961	[375]	[56]	-5	hSpCas9	negative selection	516394
205101599	205101622	1	-	26472758	Raji	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-1.4254413420123813	[624]	[53]	-7	hSpCas9	negative selection	516395
205105108	205105131	1	-	26472758	Raji	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-3.140543978069986	[151]	[3]	-9	hSpCas9	negative selection	516396
205105078	205105101	1	-	26472758	Raji	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-5.327244692263125	[172]	[0]	-9	hSpCas9	negative selection	516397
205096801	205096824	1	+	26472758	K562	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.4109979717858803	[1111]	[352]	-6	hSpCas9	negative selection	707506
205103937	205103960	1	-	26472758	K562	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.0852867178126346	[185]	[36]	-7	hSpCas9	negative selection	707507
205096764	205096787	1	-	26472758	K562	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.28028919897975363	[550]	[382]	-2	hSpCas9	negative selection	707508
205100015	205100038	1	-	26472758	K562	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-1.827421274093676	[596]	[141]	-7	hSpCas9	negative selection	707509
205115857	205115880	1	-	26472758	K562	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-3.7804131253134887	[878]	[53]	-9	hSpCas9	negative selection	707510
205114902	205114925	1	-	26472758	K562	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.2340138529009061	[534]	[191]	-6	hSpCas9	negative selection	707511
205103891	205103914	1	-	26472758	K562	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	-0.6910092710374695	[567]	[296]	-4	hSpCas9	negative selection	707512
205101599	205101622	1	-	26472758	K562	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.18621562666341562	[774]	[574]	-1	hSpCas9	negative selection	707513
205105108	205105131	1	-	26472758	K562	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.876596673294919	[260]	[29]	-8	hSpCas9	negative selection	707514
205105078	205105101	1	-	26472758	K562	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.037981003034278	[179]	[36]	-7	hSpCas9	negative selection	707515
205099925	205099948	1	+	26627737	DLD1	viability	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.3466429612399091	[115]	[29,29,25]	-4	hSpCas9	negative selection	768641
205101603	205101626	1	-	26627737	DLD1	viability	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.6382334378432596	[824]	[337,565,319]	6	hSpCas9	negative selection	768642
205103937	205103960	1	-	26627737	DLD1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.7312556874462874	[405]	[10,5,36]	-9	hSpCas9	negative selection	768643
205105078	205105101	1	-	26627737	DLD1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.93221368079001	[656]	[17,17,41]	-9	hSpCas9	negative selection	768644
205114902	205114925	1	-	26627737	DLD1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-4.699167206502141	[657]	[11,11,0]	-9	hSpCas9	negative selection	768645
205115858	205115881	1	+	26627737	DLD1	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-0.07635519522491108	[518]	[204,162,101]	-1	hSpCas9	negative selection	768646
205099925	205099948	1	+	26627737	GBM cells	viability after 5 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.5427700646604103	[63]	[49,49]	7	hSpCas9	negative selection	850956
205101603	205101626	1	-	26627737	GBM cells	viability after 5 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.5399785127688845	[537]	[421,416]	7	hSpCas9	negative selection	850957
205103937	205103960	1	-	26627737	GBM cells	viability after 5 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.04761560524048447	[174]	[122,70]	0	hSpCas9	negative selection	850958
205105078	205105101	1	-	26627737	GBM cells	viability after 5 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.3480008655848317	[355]	[67,81]	-9	hSpCas9	negative selection	850959
205114902	205114925	1	-	26627737	GBM cells	viability after 5 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.11445262518107091	[421]	[288,200]	1	hSpCas9	negative selection	850960
205115858	205115881	1	+	26627737	GBM cells	viability after 5 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.09073148217684034	[217]	[134,113]	1	hSpCas9	negative selection	850961
205099925	205099948	1	+	26627737	GBM cells	viability after 13 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.6675075091146829	[63]	[90,25]	7	hSpCas9	negative selection	933271
205101603	205101626	1	-	26627737	GBM cells	viability after 13 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.6578593497034964	[537]	[459,460]	7	hSpCas9	negative selection	933272
205103937	205103960	1	-	26627737	GBM cells	viability after 13 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.24611947800022604	[174]	[57,97]	-3	hSpCas9	negative selection	933273
205105078	205105101	1	-	26627737	GBM cells	viability after 13 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.1740418463903737	[355]	[60,27]	-9	hSpCas9	negative selection	933274
205114902	205114925	1	-	26627737	GBM cells	viability after 13 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.3344238833603119	[421]	[307,272]	4	hSpCas9	negative selection	933275
205115858	205115881	1	+	26627737	GBM cells	viability after 13 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.6655705207305954	[217]	[180,192]	7	hSpCas9	negative selection	933276
205099925	205099948	1	+	26627737	GBM cells	viability after 21 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.724399181245631	[63]	[19,21]	-6	hSpCas9	negative selection	1015586
205101603	205101626	1	-	26627737	GBM cells	viability after 21 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.559496530180706	[537]	[459,403]	6	hSpCas9	negative selection	1015587
205103937	205103960	1	-	26627737	GBM cells	viability after 21 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.5572674321857645	[174]	[61,66]	-5	hSpCas9	negative selection	1015588
205105078	205105101	1	-	26627737	GBM cells	viability after 21 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.224328517443528	[355]	[43,38]	-9	hSpCas9	negative selection	1015589
205114902	205114925	1	-	26627737	GBM cells	viability after 21 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.32783408271604086	[421]	[316,260]	3	hSpCas9	negative selection	1015590
205115858	205115881	1	+	26627737	GBM cells	viability after 21 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-0.1729423786538189	[217]	[91,116]	-1	hSpCas9	negative selection	1015591
205099925	205099948	1	+	26627737	RPE1	viability after 9 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	1.8818144680575466	[97]	[85,147]	8	hSpCas9	negative selection	1097901
205101603	205101626	1	-	26627737	RPE1	viability after 9 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.22168441090455593	[2020]	[608,903]	1	hSpCas9	negative selection	1097902
205103937	205103960	1	-	26627737	RPE1	viability after 9 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.556255592814915	[961]	[180,0]	-8	hSpCas9	negative selection	1097903
205105078	205105101	1	-	26627737	RPE1	viability after 9 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.3404615506602786	[1092]	[36,106]	-9	hSpCas9	negative selection	1097904
205114902	205114925	1	-	26627737	RPE1	viability after 9 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-2.4583112937265996	[1659]	[94,93]	-9	hSpCas9	negative selection	1097905
205115858	205115881	1	+	26627737	RPE1	viability after 9 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-0.17789965953558573	[324]	[61,125]	-1	hSpCas9	negative selection	1097906
205099925	205099948	1	+	26627737	RPE1	viability after 12 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	1.2678125028099747	[97]	[76,48]	7	hSpCas9	negative selection	1180216
205101603	205101626	1	-	26627737	RPE1	viability after 12 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.11043664432575384	[2020]	[608,561]	0	hSpCas9	negative selection	1180217
205103937	205103960	1	-	26627737	RPE1	viability after 12 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-3.1332360716737626	[961]	[44,12]	-9	hSpCas9	negative selection	1180218
205105078	205105101	1	-	26627737	RPE1	viability after 12 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.869868411871198	[1092]	[28,51]	-9	hSpCas9	negative selection	1180219
205114902	205114925	1	-	26627737	RPE1	viability after 12 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-2.1051803909775932	[1659]	[57,151]	-8	hSpCas9	negative selection	1180220
205115858	205115881	1	+	26627737	RPE1	viability after 12 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-0.869245783149293	[324]	[23,72]	-5	hSpCas9	negative selection	1180221
205099925	205099948	1	+	26627737	RPE1	viability after 15 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	1.5101585599143597	[97]	[80,76]	7	hSpCas9	negative selection	1262531
205101603	205101626	1	-	26627737	RPE1	viability after 15 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.14956889768429638	[2020]	[653,614]	1	hSpCas9	negative selection	1262532
205103937	205103960	1	-	26627737	RPE1	viability after 15 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-6.520695672864766	[961]	[4,0]	-9	hSpCas9	negative selection	1262533
205105078	205105101	1	-	26627737	RPE1	viability after 15 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.7833073062534983	[1092]	[77,12]	-9	hSpCas9	negative selection	1262534
205114902	205114925	1	-	26627737	RPE1	viability after 15 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.7700330289390327	[1659]	[239,38]	-8	hSpCas9	negative selection	1262535
205115858	205115881	1	+	26627737	RPE1	viability after 15 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.094992431208621	[324]	[68,17]	-6	hSpCas9	negative selection	1262536
205099925	205099948	1	+	26627737	RPE1	viability after 18 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.7088355179040882	[97]	[78,4]	4	hSpCas9	negative selection	1344846
205101603	205101626	1	-	26627737	RPE1	viability after 18 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.1405931867340542	[2020]	[709,484]	0	hSpCas9	negative selection	1344847
205103937	205103960	1	-	26627737	RPE1	viability after 18 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-3.1376976673902925	[961]	[43,13]	-9	hSpCas9	negative selection	1344848
205105078	205105101	1	-	26627737	RPE1	viability after 18 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-4.4406857200162015	[1092]	[15,10]	-9	hSpCas9	negative selection	1344849
205114902	205114925	1	-	26627737	RPE1	viability after 18 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-2.6884073843008442	[1659]	[83,53]	-9	hSpCas9	negative selection	1344850
205115858	205115881	1	+	26627737	RPE1	viability after 18 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-2.3061329932814756	[324]	[9,25]	-8	hSpCas9	negative selection	1344851
205099925	205099948	1	+	26627737	HeLa	viability after 8 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.4669932273159523	[173]	[211,115,15]	4	hSpCas9	negative selection	1427161
205101603	205101626	1	-	26627737	HeLa	viability after 8 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.6698103697922861	[552]	[421,395,341]	6	hSpCas9	negative selection	1427162
205103937	205103960	1	-	26627737	HeLa	viability after 8 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.3458655954313832	[14]	[0,0,11]	-3	hSpCas9	negative selection	1427163
205105078	205105101	1	-	26627737	HeLa	viability after 8 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.9529703818460975	[567]	[107,25,66]	-9	hSpCas9	negative selection	1427164
205114902	205114925	1	-	26627737	HeLa	viability after 8 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.3853000413421652	[334]	[284,160,148]	3	hSpCas9	negative selection	1427165
205115858	205115881	1	+	26627737	HeLa	viability after 8 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.30438735661029	[309]	[95,277,113]	3	hSpCas9	negative selection	1427166
205099925	205099948	1	+	26627737	HeLa	viability after 12 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.18639628801771269	[173]	[158,31,61]	1	hSpCas9	negative selection	1509476
205101603	205101626	1	-	26627737	HeLa	viability after 12 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.6979865906063765	[552]	[372,363,375]	5	hSpCas9	negative selection	1509477
205103937	205103960	1	-	26627737	HeLa	viability after 12 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.632032468407205	[14]	[0,0,0]	-9	hSpCas9	negative selection	1509478
205105078	205105101	1	-	26627737	HeLa	viability after 12 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.690276904481002	[567]	[68,17,24]	-9	hSpCas9	negative selection	1509479
205114902	205114925	1	-	26627737	HeLa	viability after 12 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.4727230165322054	[334]	[199,159,219]	4	hSpCas9	negative selection	1509480
205115858	205115881	1	+	26627737	HeLa	viability after 12 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.13970815187343877	[309]	[164,94,168]	1	hSpCas9	negative selection	1509481
205099925	205099948	1	+	26627737	HeLa	viability after 15 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.16518036444304296	[173]	[27,25,141]	-1	hSpCas9	negative selection	1591791
205101603	205101626	1	-	26627737	HeLa	viability after 15 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.5787388936153279	[552]	[289,410,305]	5	hSpCas9	negative selection	1591792
205103937	205103960	1	-	26627737	HeLa	viability after 15 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	1.50687027231996	[14]	[0,0,52]	8	hSpCas9	negative selection	1591793
205105078	205105101	1	-	26627737	HeLa	viability after 15 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.8734501574774112	[567]	[1,65,126]	-9	hSpCas9	negative selection	1591794
205114902	205114925	1	-	26627737	HeLa	viability after 15 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.4411897984798089	[334]	[126,234,194]	3	hSpCas9	negative selection	1591795
205115858	205115881	1	+	26627737	HeLa	viability after 15 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.3638699159938202	[309]	[118,251,112]	3	hSpCas9	negative selection	1591796
205099925	205099948	1	+	26627737	HeLa	viability after 18 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.16529808907945998	[173]	[19,19,141]	-1	hSpCas9	negative selection	1674106
205101603	205101626	1	-	26627737	HeLa	viability after 18 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.5944568447643723	[552]	[193,349,305]	5	hSpCas9	negative selection	1674107
205103937	205103960	1	-	26627737	HeLa	viability after 18 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	1.526675649948214	[14]	[0,0,52]	8	hSpCas9	negative selection	1674108
205105078	205105101	1	-	26627737	HeLa	viability after 18 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.9002786112993615	[567]	[1,50,126]	-9	hSpCas9	negative selection	1674109
205114902	205114925	1	-	26627737	HeLa	viability after 18 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.44805616285744254	[334]	[84,196,194]	3	hSpCas9	negative selection	1674110
205115858	205115881	1	+	26627737	HeLa	viability after 18 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.39022921498485713	[309]	[82,211,112]	3	hSpCas9	negative selection	1674111
205099925	205099948	1	+	26627737	HCT116	viability after 6 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	1.3037422676726078	[133]	[22,67]	7	hSpCas9	negative selection	1756421
205101603	205101626	1	-	26627737	HCT116	viability after 6 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.41813506474934403	[1567]	[77,467]	2	hSpCas9	negative selection	1756422
205103937	205103960	1	-	26627737	HCT116	viability after 6 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.143555100611233	[137]	[11,0]	-8	hSpCas9	negative selection	1756423
205105078	205105101	1	-	26627737	HCT116	viability after 6 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	1.3436916846292282	[912]	[964,32]	7	hSpCas9	negative selection	1756424
205114902	205114925	1	-	26627737	HCT116	viability after 6 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.41191151089893707	[704]	[218,107]	2	hSpCas9	negative selection	1756425
205115858	205115881	1	+	26627737	HCT116	viability after 6 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.4051735573312712	[623]	[29,184]	2	hSpCas9	negative selection	1756426
205099925	205099948	1	+	26627737	HCT116	viability after 8 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.26313090745913514	[161]	[109,56,56]	-3	hSpCas9	negative selection	1838736
205101603	205101626	1	-	26627737	HCT116	viability after 8 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	-0.15044171408680418	[644]	[341,377,241]	-2	hSpCas9	negative selection	1838737
205103937	205103960	1	-	26627737	HCT116	viability after 8 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.1253668766623917	[114]	[16,46,22]	-8	hSpCas9	negative selection	1838738
205105078	205105101	1	-	26627737	HCT116	viability after 8 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-0.687366917910721	[280]	[111,101,74]	-7	hSpCas9	negative selection	1838739
205114902	205114925	1	-	26627737	HCT116	viability after 8 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.16378586434490575	[334]	[143,186,162]	-2	hSpCas9	negative selection	1838740
205115858	205115881	1	+	26627737	HCT116	viability after 8 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	1.4954835813169425	[89]	[83,153,179]	9	hSpCas9	negative selection	1838741
205099925	205099948	1	+	26627737	HCT116	viability after 9 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.3638746305457996	[133]	[78,19]	2	hSpCas9	negative selection	1921051
205101603	205101626	1	-	26627737	HCT116	viability after 9 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	-0.7211888650150862	[1567]	[258,249]	-5	hSpCas9	negative selection	1921052
205103937	205103960	1	-	26627737	HCT116	viability after 9 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-3.1619001567167366	[137]	[2,4]	-9	hSpCas9	negative selection	1921053
205105078	205105101	1	-	26627737	HCT116	viability after 9 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.46709871890147	[912]	[95,81]	-7	hSpCas9	negative selection	1921054
205114902	205114925	1	-	26627737	HCT116	viability after 9 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.7327400245816196	[704]	[509,156]	5	hSpCas9	negative selection	1921055
205115858	205115881	1	+	26627737	HCT116	viability after 9 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.3281899449867404	[623]	[92,300]	2	hSpCas9	negative selection	1921056
205099925	205099948	1	+	26627737	HCT116	viability after 12 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.08246182442377681	[161]	[79,69,90]	-1	hSpCas9	negative selection	2003366
205101603	205101626	1	-	26627737	HCT116	viability after 12 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.06551293890266252	[644]	[387,345,326]	0	hSpCas9	negative selection	2003367
205103937	205103960	1	-	26627737	HCT116	viability after 12 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.24793796348568753	[114]	[11,46,96]	-3	hSpCas9	negative selection	2003368
205105078	205105101	1	-	26627737	HCT116	viability after 12 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.469334922340228	[280]	[6,37,36]	-9	hSpCas9	negative selection	2003369
205114902	205114925	1	-	26627737	HCT116	viability after 12 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.1151904143693798	[334]	[199,180,189]	1	hSpCas9	negative selection	2003370
205115858	205115881	1	+	26627737	HCT116	viability after 12 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	1.2072684340942692	[89]	[112,96,116]	8	hSpCas9	negative selection	2003371
205099925	205099948	1	+	26627737	HCT116	viability after 15 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.044900239971827904	[161]	[80,61,125]	0	hSpCas9	negative selection	2085681
205101603	205101626	1	-	26627737	HCT116	viability after 15 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	-0.21499827635627533	[644]	[311,280,362]	-2	hSpCas9	negative selection	2085682
205103937	205103960	1	-	26627737	HCT116	viability after 15 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-3.0056755900175327	[114]	[1,20,0]	-9	hSpCas9	negative selection	2085683
205105078	205105101	1	-	26627737	HCT116	viability after 15 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.45999586541936	[280]	[25,86,58]	-8	hSpCas9	negative selection	2085684
205114902	205114925	1	-	26627737	HCT116	viability after 15 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.09423518222688637	[334]	[86,151,288]	-1	hSpCas9	negative selection	2085685
205115858	205115881	1	+	26627737	HCT116	viability after 15 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	2.0927372394480295	[89]	[169,158,324]	9	hSpCas9	negative selection	2085686
205099925	205099948	1	+	26627737	HCT116	viability after 18 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.13460986644330786	[161]	[62,74,75]	-1	hSpCas9	negative selection	2167996
205101603	205101626	1	-	26627737	HCT116	viability after 18 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.014733536012135895	[644]	[404,235,308]	0	hSpCas9	negative selection	2167997
205103937	205103960	1	-	26627737	HCT116	viability after 18 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-5.400797513693572	[114]	[0,0,1]	-9	hSpCas9	negative selection	2167998
205105078	205105101	1	-	26627737	HCT116	viability after 18 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.0595022244308256	[280]	[1,85,4]	-9	hSpCas9	negative selection	2167999
205114902	205114925	1	-	26627737	HCT116	viability after 18 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.7746968225232471	[334]	[43,123,114]	-6	hSpCas9	negative selection	2168000
205115858	205115881	1	+	26627737	HCT116	viability after 18 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.9903777437742567	[89]	[50,60,151]	7	hSpCas9	negative selection	2168001
205101608	205101631	1	-	24336569	HL60	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	1.5815009120935328	[95]	[607]	9	hSpCas9	negative selection	2288582
205101617	205101640	1	+	24336569	HL60	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	-0.5376402947012267	[663]	[967]	-5	hSpCas9	negative selection	2288583
205101647	205101670	1	+	24336569	HL60	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-2.1634277311359305	[850]	[401]	-9	hSpCas9	negative selection	2288584
205103905	205103928	1	+	24336569	HL60	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	0.11527973333694114	[680]	[1560]	1	hSpCas9	negative selection	2288585
205103910	205103933	1	-	24336569	HL60	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-0.024966915516575372	[963]	[2004]	0	hSpCas9	negative selection	2288586
205103921	205103944	1	+	24336569	HL60	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-0.9898751900098685	[1067]	[1137]	-7	hSpCas9	negative selection	2288587
205103937	205103960	1	-	24336569	HL60	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	1.189522428595291	[97]	[472]	8	hSpCas9	negative selection	2288588
205103949	205103972	1	+	24336569	HL60	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	0.7351016746286492	[512]	[1806]	6	hSpCas9	negative selection	2288589
205103963	205103986	1	+	24336569	HL60	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-0.4540119912091807	[1025]	[1584]	-4	hSpCas9	negative selection	2288590
205103977	205104000	1	+	24336569	HL60	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	0.007456155677084464	[1163]	[2475]	0	hSpCas9	negative selection	2288591
205101608	205101631	1	-	24336569	KBM7	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	-0.049228826202917686	[249]	[658]	0	hSpCas9	negative selection	2355759
205101617	205101640	1	+	24336569	KBM7	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	0.6386289453550397	[202]	[861]	6	hSpCas9	negative selection	2355760
205101647	205101670	1	+	24336569	KBM7	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-2.123337235823274	[622]	[389]	-8	hSpCas9	negative selection	2355761
205103905	205103928	1	+	24336569	KBM7	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.48438116003841	[535]	[1044]	-4	hSpCas9	negative selection	2355762
205103910	205103933	1	-	24336569	KBM7	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-0.18673456352237205	[988]	[2369]	-1	hSpCas9	negative selection	2355763
205103921	205103944	1	+	24336569	KBM7	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-2.5840617046575547	[1129]	[513]	-9	hSpCas9	negative selection	2355764
205103937	205103960	1	-	24336569	KBM7	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.9600291974856705	[193]	[67]	-9	hSpCas9	negative selection	2355765
205103949	205103972	1	+	24336569	KBM7	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	0.24092090828068458	[559]	[1804]	2	hSpCas9	negative selection	2355766
205103963	205103986	1	+	24336569	KBM7	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-0.46607554016627195	[627]	[1239]	-4	hSpCas9	negative selection	2355767
205103977	205104000	1	+	24336569	KBM7	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	0.31600892102708644	[697]	[2369]	3	hSpCas9	negative selection	2355768
205118398	205118421	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTTGAGACCAGCTGAG	RBBP5	ENSG00000117222	0.362963240197711	[121,64]	[24,26]	1	dCas9-VP64	positive selection	2472591
205118398	205118421	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTTGAGACCAGCTGAG	RBBP5	ENSG00000117222	-1.016658803330618	[35,140]	[14,11]	-8	dCas9-VP64	positive selection	2567846
205103921	205103944	1	+	27260157	DLD1	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-1.6021586040889	[]	[]	-8	hSpCas9	negative selection	2574146
205114900	205114923	1	-	27260157	DLD1	viability	ACTTGCACCTTTAACAGGTGGGG	RBBP5	ENSG00000117222	-1.24566859344067	[]	[]	-7	hSpCas9	negative selection	2576769
205101647	205101670	1	+	27260157	DLD1	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-2.83586872610166	[]	[]	-9	hSpCas9	negative selection	2581446
205101608	205101631	1	-	27260157	DLD1	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.395600773814719	[]	[]	4	hSpCas9	negative selection	2584616
205103905	205103928	1	+	27260157	DLD1	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.652362257461713	[]	[]	-5	hSpCas9	negative selection	2587682
205121859	205121882	1	+	27260157	DLD1	viability	CAACTCGAGGTTCATCCCTGCGG	RBBP5	ENSG00000117222	0.477099161742092	[]	[]	8	hSpCas9	negative selection	2604834
205103949	205103972	1	+	27260157	DLD1	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	-0.000835782867623482	[]	[]	0	hSpCas9	negative selection	2604904
205114853	205114876	1	-	27260157	DLD1	viability	TGATGGCCGAATTGTCATCTGGG	RBBP5	ENSG00000117222	-1.54641031086938	[]	[]	-8	hSpCas9	negative selection	2605565
205103910	205103933	1	-	27260157	DLD1	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-1.08027858773295	[]	[]	-7	hSpCas9	negative selection	2608057
205115858	205115881	1	+	27260157	DLD1	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.57413300461407	[]	[]	-8	hSpCas9	negative selection	2609182
205103937	205103960	1	-	27260157	DLD1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.6879845782384	[]	[]	-8	hSpCas9	negative selection	2612310
205103977	205104000	1	+	27260157	DLD1	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	-0.508599004358482	[]	[]	-4	hSpCas9	negative selection	2614076
205105154	205105177	1	-	27260157	DLD1	viability	TTCCTCAGCTGGAGCCGAGATGG	RBBP5	ENSG00000117222	-0.984187682894265	[]	[]	-7	hSpCas9	negative selection	2619168
205114870	205114893	1	-	27260157	DLD1	viability	CTTGCAGTTGGCTGTAATGATGG	RBBP5	ENSG00000117222	-2.04199044370022	[]	[]	-8	hSpCas9	negative selection	2619774
205101617	205101640	1	+	27260157	DLD1	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	0.407199669670814	[]	[]	4	hSpCas9	negative selection	2620084
205105078	205105101	1	-	27260157	DLD1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.8948520333469	[]	[]	-8	hSpCas9	negative selection	2622681
205105094	205105117	1	-	27260157	DLD1	viability	TCACAGTGGGATGTTCTTTCAGG	RBBP5	ENSG00000117222	-3.34067684625999	[]	[]	-9	hSpCas9	negative selection	2623881
205115873	205115896	1	-	27260157	DLD1	viability	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-2.1797369861757	[]	[]	-9	hSpCas9	negative selection	2643201
205103963	205103986	1	+	27260157	DLD1	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-3.69139142431525	[]	[]	-9	hSpCas9	negative selection	2649116
205105062	205105085	1	+	27260157	DLD1	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-2.87239151623039	[]	[]	-9	hSpCas9	negative selection	2649438
205103921	205103944	1	+	27260157	HT1080	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-1.34037779333834	[]	[]	-9	hSpCas9	negative selection	2650276
205114900	205114923	1	-	27260157	HT1080	viability	ACTTGCACCTTTAACAGGTGGGG	RBBP5	ENSG00000117222	-0.75547034805208	[]	[]	-8	hSpCas9	negative selection	2652899
205101647	205101670	1	+	27260157	HT1080	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-1.9763132735688	[]	[]	-9	hSpCas9	negative selection	2657576
205101608	205101631	1	-	27260157	HT1080	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.433401569681889	[]	[]	4	hSpCas9	negative selection	2660746
205103905	205103928	1	+	27260157	HT1080	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.402074587905265	[]	[]	-7	hSpCas9	negative selection	2663812
205121859	205121882	1	+	27260157	HT1080	viability	CAACTCGAGGTTCATCCCTGCGG	RBBP5	ENSG00000117222	0.127538429094551	[]	[]	1	hSpCas9	negative selection	2680964
205103949	205103972	1	+	27260157	HT1080	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	-0.0169656518242843	[]	[]	0	hSpCas9	negative selection	2681034
205114853	205114876	1	-	27260157	HT1080	viability	TGATGGCCGAATTGTCATCTGGG	RBBP5	ENSG00000117222	-0.0280649535980926	[]	[]	0	hSpCas9	negative selection	2681695
205103910	205103933	1	-	27260157	HT1080	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-0.941971856534159	[]	[]	-8	hSpCas9	negative selection	2684187
205115858	205115881	1	+	27260157	HT1080	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.50225973275461	[]	[]	-9	hSpCas9	negative selection	2685312
205103937	205103960	1	-	27260157	HT1080	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.280933908516	[]	[]	-9	hSpCas9	negative selection	2688440
205103977	205104000	1	+	27260157	HT1080	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	-1.04909994089619	[]	[]	-8	hSpCas9	negative selection	2690206
205105154	205105177	1	-	27260157	HT1080	viability	TTCCTCAGCTGGAGCCGAGATGG	RBBP5	ENSG00000117222	-2.11754594165362	[]	[]	-9	hSpCas9	negative selection	2695298
205114870	205114893	1	-	27260157	HT1080	viability	CTTGCAGTTGGCTGTAATGATGG	RBBP5	ENSG00000117222	-2.37353933058801	[]	[]	-9	hSpCas9	negative selection	2695904
205101617	205101640	1	+	27260157	HT1080	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	0.120415662459747	[]	[]	1	hSpCas9	negative selection	2696214
205105078	205105101	1	-	27260157	HT1080	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.47798262728174	[]	[]	-9	hSpCas9	negative selection	2698811
205105094	205105117	1	-	27260157	HT1080	viability	TCACAGTGGGATGTTCTTTCAGG	RBBP5	ENSG00000117222	-1.88196103317077	[]	[]	-9	hSpCas9	negative selection	2700011
205115873	205115896	1	-	27260157	HT1080	viability	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-3.54989324533976	[]	[]	-9	hSpCas9	negative selection	2719331
205103963	205103986	1	+	27260157	HT1080	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-4.14865424100649	[]	[]	-9	hSpCas9	negative selection	2725246
205105062	205105085	1	+	27260157	HT1080	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-2.08821676979398	[]	[]	-9	hSpCas9	negative selection	2725568
205103921	205103944	1	+	27260157	MKN45	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-1.66444299025118	[]	[]	-9	hSpCas9	negative selection	2726406
205114900	205114923	1	-	27260157	MKN45	viability	ACTTGCACCTTTAACAGGTGGGG	RBBP5	ENSG00000117222	-0.874174370716878	[]	[]	-7	hSpCas9	negative selection	2729029
205101647	205101670	1	+	27260157	MKN45	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-1.21436253797994	[]	[]	-8	hSpCas9	negative selection	2733706
205101608	205101631	1	-	27260157	MKN45	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	-0.0434271926221075	[]	[]	0	hSpCas9	negative selection	2736876
205103905	205103928	1	+	27260157	MKN45	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.0714766149784281	[]	[]	0	hSpCas9	negative selection	2739942
205121859	205121882	1	+	27260157	MKN45	viability	CAACTCGAGGTTCATCCCTGCGG	RBBP5	ENSG00000117222	-0.508832610004767	[]	[]	-6	hSpCas9	negative selection	2757094
205103949	205103972	1	+	27260157	MKN45	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	-0.222852854622104	[]	[]	-1	hSpCas9	negative selection	2757164
205114853	205114876	1	-	27260157	MKN45	viability	TGATGGCCGAATTGTCATCTGGG	RBBP5	ENSG00000117222	-0.18740345762126	[]	[]	0	hSpCas9	negative selection	2757825
205103910	205103933	1	-	27260157	MKN45	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-0.385670298778854	[]	[]	-1	hSpCas9	negative selection	2760317
205115858	205115881	1	+	27260157	MKN45	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.30739682445469	[]	[]	-8	hSpCas9	negative selection	2761442
205103937	205103960	1	-	27260157	MKN45	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.03425915039658	[]	[]	-9	hSpCas9	negative selection	2764570
205103977	205104000	1	+	27260157	MKN45	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	0.0777927517730539	[]	[]	0	hSpCas9	negative selection	2766336
205105154	205105177	1	-	27260157	MKN45	viability	TTCCTCAGCTGGAGCCGAGATGG	RBBP5	ENSG00000117222	-1.0686139326772	[]	[]	-8	hSpCas9	negative selection	2771428
205114870	205114893	1	-	27260157	MKN45	viability	CTTGCAGTTGGCTGTAATGATGG	RBBP5	ENSG00000117222	-2.03740171379046	[]	[]	-9	hSpCas9	negative selection	2772034
205101617	205101640	1	+	27260157	MKN45	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	-0.16767823954494	[]	[]	0	hSpCas9	negative selection	2772344
205105078	205105101	1	-	27260157	MKN45	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.95077371803	[]	[]	-9	hSpCas9	negative selection	2774941
205105094	205105117	1	-	27260157	MKN45	viability	TCACAGTGGGATGTTCTTTCAGG	RBBP5	ENSG00000117222	-3.29549615108969	[]	[]	-9	hSpCas9	negative selection	2776141
205115873	205115896	1	-	27260157	MKN45	viability	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-2.86227368654329	[]	[]	-9	hSpCas9	negative selection	2795461
205103963	205103986	1	+	27260157	MKN45	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-2.32516775631076	[]	[]	-9	hSpCas9	negative selection	2801376
205105062	205105085	1	+	27260157	MKN45	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.74950631847948	[]	[]	-9	hSpCas9	negative selection	2801698
205103921	205103944	1	+	27260157	RKO	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-1.47145352797974	[]	[]	-8	hSpCas9	negative selection	2802536
205114900	205114923	1	-	27260157	RKO	viability	ACTTGCACCTTTAACAGGTGGGG	RBBP5	ENSG00000117222	-0.204003867351328	[]	[]	-1	hSpCas9	negative selection	2805159
205101647	205101670	1	+	27260157	RKO	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-2.65761608568986	[]	[]	-9	hSpCas9	negative selection	2809836
205101608	205101631	1	-	27260157	RKO	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.615951406533082	[]	[]	3	hSpCas9	negative selection	2813006
205103905	205103928	1	+	27260157	RKO	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.02863376624793	[]	[]	-8	hSpCas9	negative selection	2816072
205121859	205121882	1	+	27260157	RKO	viability	CAACTCGAGGTTCATCCCTGCGG	RBBP5	ENSG00000117222	-0.0379606013591499	[]	[]	0	hSpCas9	negative selection	2833224
205103949	205103972	1	+	27260157	RKO	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	-0.41063543767064	[]	[]	-6	hSpCas9	negative selection	2833294
205114853	205114876	1	-	27260157	RKO	viability	TGATGGCCGAATTGTCATCTGGG	RBBP5	ENSG00000117222	-0.757516821883341	[]	[]	-7	hSpCas9	negative selection	2833955
205103910	205103933	1	-	27260157	RKO	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-0.755097702748678	[]	[]	-7	hSpCas9	negative selection	2836447
205115858	205115881	1	+	27260157	RKO	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.86627235274321	[]	[]	-9	hSpCas9	negative selection	2837572
205103937	205103960	1	-	27260157	RKO	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.58236351496878	[]	[]	-9	hSpCas9	negative selection	2840700
205103977	205104000	1	+	27260157	RKO	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	-0.936321647393839	[]	[]	-8	hSpCas9	negative selection	2842466
205105154	205105177	1	-	27260157	RKO	viability	TTCCTCAGCTGGAGCCGAGATGG	RBBP5	ENSG00000117222	-2.72909829136568	[]	[]	-9	hSpCas9	negative selection	2847558
205114870	205114893	1	-	27260157	RKO	viability	CTTGCAGTTGGCTGTAATGATGG	RBBP5	ENSG00000117222	-2.32924025575882	[]	[]	-9	hSpCas9	negative selection	2848164
205101617	205101640	1	+	27260157	RKO	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	0.267617642185892	[]	[]	1	hSpCas9	negative selection	2848474
205105078	205105101	1	-	27260157	RKO	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.80871863800296	[]	[]	-9	hSpCas9	negative selection	2851071
205105094	205105117	1	-	27260157	RKO	viability	TCACAGTGGGATGTTCTTTCAGG	RBBP5	ENSG00000117222	-2.05572815681922	[]	[]	-9	hSpCas9	negative selection	2852271
205115873	205115896	1	-	27260157	RKO	viability	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-2.59203531722731	[]	[]	-9	hSpCas9	negative selection	2871591
205103963	205103986	1	+	27260157	RKO	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-3.58285368638922	[]	[]	-9	hSpCas9	negative selection	2877506
205105062	205105085	1	+	27260157	RKO	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-2.70869025035202	[]	[]	-9	hSpCas9	negative selection	2877828
205103921	205103944	1	+	27260157	SF268	viability	AAATCGGAGTCATCGTCCACCGG	RBBP5	ENSG00000117222	-1.71630148041899	[]	[]	-8	hSpCas9	negative selection	2878666
205114900	205114923	1	-	27260157	SF268	viability	ACTTGCACCTTTAACAGGTGGGG	RBBP5	ENSG00000117222	-0.432600912078087	[]	[]	-3	hSpCas9	negative selection	2881289
205101647	205101670	1	+	27260157	SF268	viability	TGTTCCAGTTGTCACTCTGAAGG	RBBP5	ENSG00000117222	-2.59045139249555	[]	[]	-9	hSpCas9	negative selection	2885966
205101608	205101631	1	-	27260157	SF268	viability	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.199883592051334	[]	[]	3	hSpCas9	negative selection	2889136
205103905	205103928	1	+	27260157	SF268	viability	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.51844126334819	[]	[]	-8	hSpCas9	negative selection	2892202
205121859	205121882	1	+	27260157	SF268	viability	CAACTCGAGGTTCATCCCTGCGG	RBBP5	ENSG00000117222	0.566801330267757	[]	[]	8	hSpCas9	negative selection	2909354
205103949	205103972	1	+	27260157	SF268	viability	CAACATGTTTGGAATCTGAAAGG	RBBP5	ENSG00000117222	-0.587854378144263	[]	[]	-4	hSpCas9	negative selection	2909424
205114853	205114876	1	-	27260157	SF268	viability	TGATGGCCGAATTGTCATCTGGG	RBBP5	ENSG00000117222	-0.715314416052452	[]	[]	-5	hSpCas9	negative selection	2910085
205103910	205103933	1	-	27260157	SF268	viability	TGACTCCGATTTGAACGTTGTGG	RBBP5	ENSG00000117222	-1.08418939311109	[]	[]	-7	hSpCas9	negative selection	2912577
205115858	205115881	1	+	27260157	SF268	viability	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-1.26987320808279	[]	[]	-7	hSpCas9	negative selection	2913702
205103937	205103960	1	-	27260157	SF268	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-2.28004493864097	[]	[]	-9	hSpCas9	negative selection	2916830
205103977	205104000	1	+	27260157	SF268	viability	CATGACAGGAGCAGATTTCATGG	RBBP5	ENSG00000117222	-1.55592159761615	[]	[]	-8	hSpCas9	negative selection	2918596
205105154	205105177	1	-	27260157	SF268	viability	TTCCTCAGCTGGAGCCGAGATGG	RBBP5	ENSG00000117222	-2.17078309725452	[]	[]	-9	hSpCas9	negative selection	2923688
205114870	205114893	1	-	27260157	SF268	viability	CTTGCAGTTGGCTGTAATGATGG	RBBP5	ENSG00000117222	-2.11754215578167	[]	[]	-9	hSpCas9	negative selection	2924294
205101617	205101640	1	+	27260157	SF268	viability	CTCAATTGACTTAATGGCTGTGG	RBBP5	ENSG00000117222	0.0182977853512332	[]	[]	0	hSpCas9	negative selection	2924604
205105078	205105101	1	-	27260157	SF268	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.33226025134225	[]	[]	-9	hSpCas9	negative selection	2927201
205105094	205105117	1	-	27260157	SF268	viability	TCACAGTGGGATGTTCTTTCAGG	RBBP5	ENSG00000117222	-3.06674132393042	[]	[]	-9	hSpCas9	negative selection	2928401
205115873	205115896	1	-	27260157	SF268	viability	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-1.21803817974995	[]	[]	-7	hSpCas9	negative selection	2947721
205103963	205103986	1	+	27260157	SF268	viability	TCTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-3.79118183301686	[]	[]	-9	hSpCas9	negative selection	2953636
205105062	205105085	1	+	27260157	SF268	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.70708376519713	[]	[]	-8	hSpCas9	negative selection	2953958
205115857	205115880	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-0.7096680626156993	[3,3]	[1,0]	-8	hSpCas9	positive selection	3015877
205115873	205115896	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	0.026900135121663324	[3,3]	[4,2]	0	hSpCas9	positive selection	3015878
205114784	205114807	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	-1.0106655081896199	[3,3]	[1,0]	-9	hSpCas9	positive selection	3015879
205105078	205105101	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	0.14997452312285944	[2,3]	[3,2]	3	hSpCas9	positive selection	3015880
205115857	205115880	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-0.33394563145849737	[3,3]	[2,0]	-5	hSpCas9	positive selection	3083735
205115873	205115896	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	-0.31127109162321964	[3,3]	[3,0]	-5	hSpCas9	positive selection	3083736
205114784	205114807	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	-0.1113378833406129	[3,3]	[2,1]	-2	hSpCas9	positive selection	3083737
205105078	205105101	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	0.3635645817722787	[2,2]	[3,1]	6	hSpCas9	positive selection	3083738
205121855	205121878		-	24336571	A375	resistance to PLX after 7 days	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.04946318309223424	[17,16]	[17,17]	1	hSpCas9	positive selection	3140002
205121846	205121869		+	24336571	A375	resistance to PLX after 7 days	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.30617039514016287	[5,5]	[6,8]	8	hSpCas9	positive selection	3140004
205105111	205105134		+	24336571	A375	resistance to PLX after 7 days	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	0.41760603607423064	[5,5]	[7,6]	9	hSpCas9	positive selection	3140005
205105078	205105101		-	24336571	A375	resistance to PLX after 7 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	0.6163941853551427	[4,5]	[8,8]	9	hSpCas9	positive selection	3140006
205121855	205121878		-	24336571	A375	resistance to PLX after 14 days	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	1.1034997122171637	[13,11]	[12,12]	8	hSpCas9	positive selection	3197795
205121846	205121869		+	24336571	A375	resistance to PLX after 14 days	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.0934269820832998	[3,4]	[1,1]	1	hSpCas9	positive selection	3197797
205105111	205105134		+	24336571	A375	resistance to PLX after 14 days	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	0.4101744841663131	[6,3]	[2,2]	4	hSpCas9	positive selection	3197798
205105078	205105101		-	24336571	A375	resistance to PLX after 14 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	0.5078025542023206	[4,4]	[2,3]	5	hSpCas9	positive selection	3197799
205121855	205121878		-	24336571	A375	viability after 7 days	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.4810469713879533	[12]	[17,16]	7	hSpCas9	negative selection	3255588
205121846	205121869		+	24336571	A375	viability after 7 days	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.8336600437356956	[24]	[5,5]	-9	hSpCas9	negative selection	3255590
205105111	205105134		+	24336571	A375	viability after 7 days	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	-1.708626587549718	[20]	[5,5]	-9	hSpCas9	negative selection	3255591
205105078	205105101		-	24336571	A375	viability after 7 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.8382073193565267	[21]	[4,5]	-9	hSpCas9	negative selection	3255592
205121855	205121878		-	24336571	A375	viability after 14 days	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.08626550967749785	[12]	[13,11]	1	hSpCas9	negative selection	3313381
205121846	205121869		+	24336571	A375	viability after 14 days	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-2.2201807834579492	[24]	[3,4]	-9	hSpCas9	negative selection	3313383
205105111	205105134		+	24336571	A375	viability after 14 days	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	-1.8122606193653255	[20]	[6,3]	-9	hSpCas9	negative selection	3313384
205105078	205105101		-	24336571	A375	viability after 14 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.869210865726464	[21]	[4,4]	-9	hSpCas9	negative selection	3313385
205121846	205121869	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.8248228299080366	[270,270]	[0,0]	-5	hSpCas9	positive selection	3389142
205100224	205100247	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3389143
205100165	205100188	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-1.1689385432562627	[343,343]	[0,0]	-7	hSpCas9	positive selection	3389144
205115857	205115880	1	-	26780180	HT29	viability (Avana library 4 designs)	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	4.96228279894799	[]	[]	9	hSpCas9	negative selection	3454145
205115873	205115896	1	-	26780180	HT29	viability (Avana library 4 designs)	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	0.273455109599857	[]	[]	1	hSpCas9	negative selection	3454146
205114783	205114806	1	+	26780180	HT29	viability (Avana library 4 designs)	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	5.96652772768089	[]	[]	9	hSpCas9	negative selection	3454147
205105078	205105101	1	-	26780180	HT29	viability (Avana library 4 designs)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	4.04123814374029	[]	[]	9	hSpCas9	negative selection	3454148
205115857	205115880	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-10.0609606827805	[]	[]	-7	hSpCas9	negative selection	3551349
205105078	205105101	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-10.9418645719247	[]	[]	-8	hSpCas9	negative selection	3551350
205115873	205115896	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	5.4544451488507	[]	[]	8	hSpCas9	negative selection	3551351
205114783	205114806	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	-22.9274541858817	[]	[]	-9	hSpCas9	negative selection	3551352
205101608	205101631	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.496333473328284	[]	[]	0	hSpCas9	negative selection	3551353
205103905	205103928	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	0.0149184100658716	[]	[]	0	hSpCas9	negative selection	3551354
205115857	205115880	1	-	26780180	A375	viability (Avana lentiGuide)	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	12.4681953396382	[]	[]	7	hSpCas9	negative selection	3660008
205105078	205105101	1	-	26780180	A375	viability (Avana lentiGuide)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	17.4425191230932	[]	[]	8	hSpCas9	negative selection	3660009
205115873	205115896	1	-	26780180	A375	viability (Avana lentiGuide)	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	0.73653284343514	[]	[]	0	hSpCas9	negative selection	3660010
205114783	205114806	1	+	26780180	A375	viability (Avana lentiGuide)	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	24.9349023258547	[]	[]	9	hSpCas9	negative selection	3660011
205101608	205101631	1	-	26780180	A375	viability (Avana lentiGuide)	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	-4.64492739613335	[]	[]	-7	hSpCas9	negative selection	3660012
205103905	205103928	1	+	26780180	A375	viability (Avana lentiGuide)	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	2.53677789277386	[]	[]	2	hSpCas9	negative selection	3660013
205115857	205115880	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-0.8537208332318809	[5]	[2,1]	-8	hSpCas9	positive selection	3768615
205105078	205105101	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.1752227923445762	[4]	[2,0]	-9	hSpCas9	positive selection	3768616
205115873	205115896	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	0.23799387869925043	[4]	[6,5]	6	hSpCas9	positive selection	3768617
205114783	205114806	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	-2.519358250469681	[6]	[0,0]	-9	hSpCas9	positive selection	3768618
205101608	205101631	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.019407743768001084	[6]	[6,5]	0	hSpCas9	positive selection	3768619
205103905	205103928	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.19920310009198647	[5]	[3,4]	-3	hSpCas9	positive selection	3768620
205115857	205115880	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-0.9206003238007009	[5]	[0,3]	-8	hSpCas9	positive selection	3877222
205105078	205105101	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.0341758460592378	[5]	[3,0]	-8	hSpCas9	positive selection	3877223
205115873	205115896	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTTGTTGCAGAGTCCTTTGGG	RBBP5	ENSG00000117222	0.05198833346393564	[6]	[5,4]	1	hSpCas9	positive selection	3877224
205114783	205114806	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTACCATAAAGAACACACTGG	RBBP5	ENSG00000117222	-0.915033304662766	[6]	[2,2]	-8	hSpCas9	positive selection	3877225
205101608	205101631	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGTCAATTGAGTTTGCCCGG	RBBP5	ENSG00000117222	0.3258546455783987	[6]	[7,7]	8	hSpCas9	positive selection	3877226
205103905	205103928	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	0.12240771740836362	[5]	[5,4]	2	hSpCas9	positive selection	3877227
205105026	205105049	1	+	26780180	A375	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	1.31313966545018	[]	[]	7	hSpCas9	negative selection	3987645
205121855	205121878	1	-	26780180	A375	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.983427634632873	[]	[]	4	hSpCas9	negative selection	3987646
205121846	205121869	1	+	26780180	A375	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	2.07718626400182	[]	[]	9	hSpCas9	negative selection	3987647
205100224	205100247	1	-	26780180	A375	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	2.45219690908501	[]	[]	9	hSpCas9	negative selection	3987648
205105062	205105085	1	+	26780180	A375	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	1.14673487645612	[]	[]	6	hSpCas9	negative selection	3987649
205100165	205100188	1	-	26780180	A375	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	1.54855559420893	[]	[]	8	hSpCas9	negative selection	3987650
205105026	205105049	1	+	26780180	HT29	viability (GeCKOv2 library)	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	1.59741965432846	[]	[]	8	hSpCas9	negative selection	4095611
205121855	205121878	1	-	26780180	HT29	viability (GeCKOv2 library)	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	1.93967908089595	[]	[]	9	hSpCas9	negative selection	4095612
205121846	205121869	1	+	26780180	HT29	viability (GeCKOv2 library)	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.432739651322302	[]	[]	1	hSpCas9	negative selection	4095613
205100224	205100247	1	-	26780180	HT29	viability (GeCKOv2 library)	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	2.82618881329409	[]	[]	9	hSpCas9	negative selection	4095614
205105062	205105085	1	+	26780180	HT29	viability (GeCKOv2 library)	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	1.53508643840039	[]	[]	7	hSpCas9	negative selection	4095615
205100165	205100188	1	-	26780180	HT29	viability (GeCKOv2 library)	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	1.00371037734638	[]	[]	4	hSpCas9	negative selection	4095616
205121855	205121878	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.234959480526508	[4]	[2,3]	6	hSpCas9	positive selection	4165377
205121846	205121869	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.7910745660507338	[3]	[0,0]	-9	hSpCas9	positive selection	4165379
205105111	205105134	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	-0.3974226310118275	[3]	[1,1]	-7	hSpCas9	positive selection	4165380
205105078	205105101	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-0.5357270425689798	[3]	[0,1]	-8	hSpCas9	positive selection	4165381
205121855	205121878	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.21690143283104515	[3]	[1,4,2,0]	1	hSpCas9	positive selection	4229399
205121846	205121869	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.010013202466448767	[4]	[2,4,0,0]	0	hSpCas9	positive selection	4229401
205105111	205105134	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTGACACTATGTTATCAGTGG	RBBP5	ENSG00000117222	-0.700152775563038	[4]	[0,2,0,0]	-8	hSpCas9	positive selection	4229402
205105078	205105101	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-0.18072997906906224	[4]	[1,0,4,0]	-3	hSpCas9	positive selection	4229403
205105026	205105049	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.04877013872307589	[2]	[3,1]	-1	hSpCas9	positive selection	4294062
205121855	205121878	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	-0.1479488497008868	[3]	[3,1]	-3	hSpCas9	positive selection	4294063
205105062	205105085	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.6879784596450856	[1]	[0,0]	-9	hSpCas9	positive selection	4294064
205121846	205121869	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.1868278919512101	[3]	[2,1]	-4	hSpCas9	positive selection	4358318
205100224	205100247	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-0.9446322161318772	[3]	[1,0]	-9	hSpCas9	positive selection	4358319
205100165	205100188	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	0.01621815301193552	[4]	[4,2]	0	hSpCas9	positive selection	4358320
205101604	205101626	1	-	27760321	OCIAML3	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	0.19030454114066625	[622,600]	[481,631]	2	hSpCas9	negative selection	4433423
205103861	205103883	1	-	27760321	OCIAML3	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	0.46041659146437297	[33,17]	[9,49]	5	hSpCas9	negative selection	4433424
205103906	205103928	1	+	27760321	OCIAML3	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.7511564951429618	[226,216]	[101,104]	-6	hSpCas9	negative selection	4433425
205103937	205103959	1	-	27760321	OCIAML3	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.16674333379622985	[1300,964]	[741,834]	-2	hSpCas9	negative selection	4433426
205103964	205103986	1	+	27760321	OCIAML3	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-0.3227817822291327	[247,213]	[117,177]	-3	hSpCas9	negative selection	4433427
205101604	205101626	1	-	27760321	OCIAML2	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	0.19722914582434287	[622,600]	[433,745]	2	hSpCas9	negative selection	4516886
205103861	205103883	1	-	27760321	OCIAML2	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-0.8649685501274647	[33,17]	[9,12]	-7	hSpCas9	negative selection	4516887
205103906	205103928	1	+	27760321	OCIAML2	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.2593792559133755	[226,216]	[154,143]	-3	hSpCas9	negative selection	4516888
205103937	205103959	1	-	27760321	OCIAML2	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.533711936351023	[1300,964]	[532,751]	-5	hSpCas9	negative selection	4516889
205103964	205103986	1	+	27760321	OCIAML2	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.4237888153709815	[247,213]	[43,102]	-8	hSpCas9	negative selection	4516890
205101604	205101626	1	-	27760321	MV411	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-0.29191467922566966	[622,600]	[421,192]	-2	hSpCas9	negative selection	4600349
205103861	205103883	1	-	27760321	MV411	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-4.068706631221767	[33,17]	[0,0]	-9	hSpCas9	negative selection	4600350
205103906	205103928	1	+	27760321	MV411	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.4351118272042759	[226,216]	[0,269]	-3	hSpCas9	negative selection	4600351
205103937	205103959	1	-	27760321	MV411	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.9768583741577668	[1300,964]	[258,552]	-6	hSpCas9	negative selection	4600352
205103964	205103986	1	+	27760321	MV411	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-2.75098037064003	[247,213]	[0,54]	-9	hSpCas9	negative selection	4600353
205101604	205101626	1	-	27760321	HL60	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	0.6031617146631401	[622,600]	[703,820]	7	hSpCas9	negative selection	4683812
205103861	205103883	1	-	27760321	HL60	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-1.3818683186159681	[33,17]	[6,8]	-8	hSpCas9	negative selection	4683813
205103906	205103928	1	+	27760321	HL60	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.910187961303946	[226,216]	[67,126]	-7	hSpCas9	negative selection	4683814
205103937	205103959	1	-	27760321	HL60	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.5442415471765792	[1300,964]	[563,697]	-5	hSpCas9	negative selection	4683815
205103964	205103986	1	+	27760321	HL60	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.1280793811219683	[247,213]	[138,29]	-8	hSpCas9	negative selection	4683816
205101604	205101626	1	-	27760321	HT1080	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-7.735566873140251	[600,468]	[0,0]	-9	hSpCas9	negative selection	4767275
205103861	205103883	1	-	27760321	HT1080	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-2.671875160129228	[17,13]	[0,0]	-7	hSpCas9	negative selection	4767276
205103906	205103928	1	+	27760321	HT1080	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-3.624651989674148	[216,169]	[0,11]	-7	hSpCas9	negative selection	4767277
205103937	205103959	1	-	27760321	HT1080	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-3.312269608937731	[964,752]	[64,0]	-7	hSpCas9	negative selection	4767278
205103964	205103986	1	+	27760321	HT1080	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-3.4955943467623034	[213,166]	[0,12]	-7	hSpCas9	negative selection	4767279
205101604	205101626	1	-	27760321	HT29	viability after 7 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-0.05052015122559961	[600,468]	[757,615,631]	0	hSpCas9	negative selection	4850738
205103861	205103883	1	-	27760321	HT29	viability after 7 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-0.008055139368786435	[17,13]	[15,33,10]	0	hSpCas9	negative selection	4850739
205103906	205103928	1	+	27760321	HT29	viability after 7 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	0.851583659827519	[216,169]	[412,532,396]	9	hSpCas9	negative selection	4850740
205103937	205103959	1	-	27760321	HT29	viability after 7 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.14135846071869063	[964,752]	[1224,825,983]	-2	hSpCas9	negative selection	4850741
205103964	205103986	1	+	27760321	HT29	viability after 7 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	0.43097492921378183	[213,166]	[294,356,332]	6	hSpCas9	negative selection	4850742
205101604	205101626	1	-	27760321	HT29	viability after 25 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-1.7944189439087288	[600,468]	[182,160,184]	-8	hSpCas9	negative selection	4934201
205103861	205103883	1	-	27760321	HT29	viability after 25 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-3.5084269725813133	[17,13]	[0,0,2]	-9	hSpCas9	negative selection	4934202
205103906	205103928	1	+	27760321	HT29	viability after 25 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.5034481139923006	[216,169]	[47,90,98]	-7	hSpCas9	negative selection	4934203
205103937	205103959	1	-	27760321	HT29	viability after 25 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.7388070727225697	[964,752]	[238,260,395]	-7	hSpCas9	negative selection	4934204
205103964	205103986	1	+	27760321	HT29	viability after 25 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-2.718085956644341	[213,166]	[12,23,66]	-8	hSpCas9	negative selection	4934205
205101604	205101626	1	-	27760321	HT29	viability after 22 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-1.388027524365134	[600,468]	[172,263,273]	-7	hSpCas9	negative selection	5017664
205103861	205103883	1	-	27760321	HT29	viability after 22 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-3.7993453558710932	[17,13]	[0,0,1]	-9	hSpCas9	negative selection	5017665
205103906	205103928	1	+	27760321	HT29	viability after 22 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.0705825319830922	[216,169]	[31,141,147]	-7	hSpCas9	negative selection	5017666
205103937	205103959	1	-	27760321	HT29	viability after 22 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.9981984487792628	[964,752]	[341,274,124]	-8	hSpCas9	negative selection	5017667
205103964	205103986	1	+	27760321	HT29	viability after 22 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.3316859436356725	[213,166]	[51,65,145]	-7	hSpCas9	negative selection	5017668
205101604	205101626	1	-	27760321	HT29	viability after 19 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-2.0708923655499243	[600,468]	[172,22,239]	-8	hSpCas9	negative selection	5101127
205103861	205103883	1	-	27760321	HT29	viability after 19 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-4.193036004411798	[17,13]	[0,0,0]	-9	hSpCas9	negative selection	5101128
205103906	205103928	1	+	27760321	HT29	viability after 19 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.255514828760778	[216,169]	[94,108,74]	-7	hSpCas9	negative selection	5101129
205103937	205103959	1	-	27760321	HT29	viability after 19 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.639511463917573	[964,752]	[257,292,385]	-7	hSpCas9	negative selection	5101130
205103964	205103986	1	+	27760321	HT29	viability after 19 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-4.274650226325348	[213,166]	[0,1,28]	-9	hSpCas9	negative selection	5101131
205101604	205101626	1	-	27760321	HT29	viability after 16 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-1.3803828728982594	[600,468]	[312,212,171]	-7	hSpCas9	negative selection	5184590
205103861	205103883	1	-	27760321	HT29	viability after 16 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-3.7285990963320277	[17,13]	[0,1,0]	-9	hSpCas9	negative selection	5184591
205103906	205103928	1	+	27760321	HT29	viability after 16 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.4862294722111803	[216,169]	[163,139,160]	-5	hSpCas9	negative selection	5184592
205103937	205103959	1	-	27760321	HT29	viability after 16 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.2866573840470714	[964,752]	[454,412,318]	-7	hSpCas9	negative selection	5184593
205103964	205103986	1	+	27760321	HT29	viability after 16 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.5733375457266323	[213,166]	[65,6,142]	-8	hSpCas9	negative selection	5184594
205101604	205101626	1	-	27760321	HT29	viability after 13 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-0.791829223906992	[600,468]	[383,428,267]	-7	hSpCas9	negative selection	5268053
205103861	205103883	1	-	27760321	HT29	viability after 13 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-1.177354171796729	[17,13]	[8,13,1]	-8	hSpCas9	negative selection	5268054
205103906	205103928	1	+	27760321	HT29	viability after 13 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-1.1643092196015918	[216,169]	[37,133,126]	-8	hSpCas9	negative selection	5268055
205103937	205103959	1	-	27760321	HT29	viability after 13 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.0754494839813447	[964,752]	[477,492,448]	-7	hSpCas9	negative selection	5268056
205103964	205103986	1	+	27760321	HT29	viability after 13 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.6948952139361078	[213,166]	[31,89,81]	-8	hSpCas9	negative selection	5268057
205101604	205101626	1	-	27760321	HT29	viability after 10 days	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-0.020637294074720258	[600,468]	[712,546,710]	0	hSpCas9	negative selection	5351516
205103861	205103883	1	-	27760321	HT29	viability after 10 days	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-0.3174476013325327	[17,13]	[45,0,0]	-4	hSpCas9	negative selection	5351517
205103906	205103928	1	+	27760321	HT29	viability after 10 days	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-0.0004965084056787195	[216,169]	[288,206,227]	0	hSpCas9	negative selection	5351518
205103937	205103959	1	-	27760321	HT29	viability after 10 days	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.359189505606331	[964,752]	[698,892,915]	-5	hSpCas9	negative selection	5351519
205103964	205103986	1	+	27760321	HT29	viability after 10 days	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-0.42875332565160484	[213,166]	[117,361,57]	-5	hSpCas9	negative selection	5351520
205101604	205101626	1	-	27760321	MOLM13	viability	TCAATTGAGTTTGCCCGGAAGG	RBBP5	ENSG00000117222	-1.4070861154823728	[622,600]	[16,226]	-7	hSpCas9	negative selection	5434979
205103861	205103883	1	-	27760321	MOLM13	viability	TTTATACGGGAAACGCAAAAGG	RBBP5	ENSG00000117222	-3.8426498183941717	[33,17]	[0,0]	-9	hSpCas9	negative selection	5434980
205103906	205103928	1	+	27760321	MOLM13	viability	GATGCCACAACGTTCAAATCGG	RBBP5	ENSG00000117222	-2.0230158258298077	[226,216]	[25,34]	-8	hSpCas9	negative selection	5434981
205103937	205103959	1	-	27760321	MOLM13	viability	AAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.14184393074479318	[1300,964]	[1283,200]	1	hSpCas9	negative selection	5434982
205103964	205103986	1	+	27760321	MOLM13	viability	CTGAAAGGGTCAACATGACAGG	RBBP5	ENSG00000117222	-1.826898116781726	[247,213]	[54,20]	-7	hSpCas9	negative selection	5434983
205121955	205121978	1	+	27661255	K562	viability	GGTGGACGCCGCGAAGAGACTGG	RBBP5	ENSG00000117222	0.44988880739449905	[423,498]	[588,427]	9	dCas9-KRAB	negative selection	5506422
205121549	205121572	1	-	27661255	K562	viability	GCAGCCAGGACCAGAGTTGTTGG	RBBP5	ENSG00000117222	0.2062667063310516	[1345,1318]	[1350,1123]	7	dCas9-KRAB	negative selection	5506423
205121763	205121786	1	-	27661255	K562	viability	GGAGTCAGGCTGCAATCTTAGGG	RBBP5	ENSG00000117222	0.05415838490282576	[891,945]	[769,753]	1	dCas9-KRAB	negative selection	5506424
205121801	205121824	1	-	27661255	K562	viability	GCGTTGGGTACTGGAAAGGAGGG	RBBP5	ENSG00000117222	-0.4552193252164891	[500,405]	[295,238]	-7	dCas9-KRAB	negative selection	5506425
205105026	205105049	1	+	27260156	BXPC3	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3367632518712182	[413]	[242,343,322,486]	-6	hSpCas9	negative selection	5566522
205121855	205121878	1	-	27260156	BXPC3	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3746247900339117	[729]	[765,944,1107,1185]	7	hSpCas9	negative selection	5566523
205105062	205105085	1	+	27260156	BXPC3	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.874492478507501	[141]	[84,59,52,131]	-9	hSpCas9	negative selection	5566524
205121846	205121869	1	+	27260156	BXPC3	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.0058559377417972125	[641]	[677,486,761,790]	0	hSpCas9	negative selection	5630778
205100224	205100247	1	-	27260156	BXPC3	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.5775450555434927	[550]	[156,216,160,243]	-9	hSpCas9	negative selection	5630779
205100165	205100188	1	-	27260156	BXPC3	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.1987223991906828	[1304]	[1150,1115,1248,1247]	-4	hSpCas9	negative selection	5630780
205105026	205105049	1	+	27260156	A673	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.488219368433447	[413]	[337,321,274,488]	-8	hSpCas9	negative selection	5687773
205121855	205121878	1	-	27260156	A673	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.08329358730143255	[729]	[949,879,900,988]	2	hSpCas9	negative selection	5687774
205105062	205105085	1	+	27260156	A673	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.35878212751035776	[141]	[225,58,130,127]	-7	hSpCas9	negative selection	5687775
205121846	205121869	1	+	27260156	A673	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.2838531999096693	[641]	[735,554,613,640]	-6	hSpCas9	negative selection	5752029
205100224	205100247	1	-	27260156	A673	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.0433506954092524	[550]	[360,307,291,327]	-9	hSpCas9	negative selection	5752030
205100165	205100188	1	-	27260156	A673	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.2343600945997899	[1304]	[1505,1189,1105,1561]	-5	hSpCas9	negative selection	5752031
205105026	205105049	1	+	27260156	A375	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.5101811530734899	[413]	[204,342,484,324]	-6	hSpCas9	negative selection	5809024
205121855	205121878	1	-	27260156	A375	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.40260564607325744	[729]	[1058,1425,1015,1052]	6	hSpCas9	negative selection	5809025
205105062	205105085	1	+	27260156	A375	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.0229730396445975	[141]	[65,94,76,88]	-8	hSpCas9	negative selection	5809026
205121846	205121869	1	+	27260156	A375	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.1680766753885332	[641]	[371,556,297,158]	-8	hSpCas9	negative selection	5873280
205100224	205100247	1	-	27260156	A375	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.9705716280346584	[550]	[80,262,148,174]	-9	hSpCas9	negative selection	5873281
205100165	205100188	1	-	27260156	A375	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.3631503704814838	[1304]	[1148,1399,1029,1185]	-5	hSpCas9	negative selection	5873282
205105026	205105049	1	+	27260156	COLO741	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.7735489467495669	[413]	[376,243,311]	-9	hSpCas9	negative selection	5930275
205121855	205121878	1	-	27260156	COLO741	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.013498530438577294	[729]	[896,1095,833]	0	hSpCas9	negative selection	5930276
205105062	205105085	1	+	27260156	COLO741	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.393725549354192	[141]	[154,88,168]	-7	hSpCas9	negative selection	5930277
205121846	205121869	1	+	27260156	COLO741	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.3386390541832085	[641]	[825,564,573]	-6	hSpCas9	negative selection	5994531
205100224	205100247	1	-	27260156	COLO741	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.3735190643666448	[550]	[349,240,232]	-9	hSpCas9	negative selection	5994532
205100165	205100188	1	-	27260156	COLO741	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.2786391118631255	[1304]	[1335,1665,1133]	-5	hSpCas9	negative selection	5994533
205105026	205105049	1	+	27260156	CAL120	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.11801159997035515	[413]	[574,744,362]	1	hSpCas9	negative selection	6051526
205121855	205121878	1	-	27260156	CAL120	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.33589787194107146	[729]	[1173,1384,888]	5	hSpCas9	negative selection	6051527
205105062	205105085	1	+	27260156	CAL120	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.0665468288024045	[141]	[86,55,109]	-8	hSpCas9	negative selection	6051528
205121846	205121869	1	+	27260156	CAL120	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.1727125473245155	[641]	[398,220,447]	-9	hSpCas9	negative selection	6115782
205100224	205100247	1	-	27260156	CAL120	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.882793887798235	[550]	[125,310,112]	-9	hSpCas9	negative selection	6115783
205100165	205100188	1	-	27260156	CAL120	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.18286627061880334	[1304]	[1719,1477,1141]	-3	hSpCas9	negative selection	6115784
205105026	205105049	1	+	27260156	CADOES1	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.644887992407825	[413]	[164,254,298,266]	-8	hSpCas9	negative selection	6172777
205121855	205121878	1	-	27260156	CADOES1	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.2741511457988606	[729]	[781,862,749,891]	4	hSpCas9	negative selection	6172778
205105062	205105085	1	+	27260156	CADOES1	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.8242695477019815	[141]	[42,112,80,60]	-8	hSpCas9	negative selection	6172779
205121846	205121869	1	+	27260156	CADOES1	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.7422526371283047	[641]	[293,258,433,443]	-8	hSpCas9	negative selection	6237033
205100224	205100247	1	-	27260156	CADOES1	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.5554311554832245	[550]	[96,250,194,153]	-9	hSpCas9	negative selection	6237034
205100165	205100188	1	-	27260156	CADOES1	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.005001147911602555	[1304]	[1186,1290,1184,1173]	0	hSpCas9	negative selection	6237035
205105026	205105049	1	+	27260156	EWS502	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3523282194466851	[413]	[235,369,401,379]	-6	hSpCas9	negative selection	6294028
205121855	205121878	1	-	27260156	EWS502	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3317202828686898	[729]	[828,1149,808,1118]	6	hSpCas9	negative selection	6294029
205105062	205105085	1	+	27260156	EWS502	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.174940993661324	[141]	[19,48,146,56]	-9	hSpCas9	negative selection	6294030
205121846	205121869	1	+	27260156	EWS502	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.017922057941021	[641]	[204,312,379,470]	-8	hSpCas9	negative selection	6358284
205100224	205100247	1	-	27260156	EWS502	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-3.1193291483115075	[550]	[80,64,62,56]	-9	hSpCas9	negative selection	6358285
205100165	205100188	1	-	27260156	EWS502	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.31884001347737656	[1304]	[1024,1094,912,1425]	-5	hSpCas9	negative selection	6358286
205105026	205105049	1	+	27260156	EW8	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3622087295459912	[413]	[240,339,270,187]	-6	hSpCas9	negative selection	6415279
205121855	205121878	1	-	27260156	EW8	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.18078945014090542	[729]	[752,655,577,717]	3	hSpCas9	negative selection	6415280
205105062	205105085	1	+	27260156	EW8	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.131046539059213	[141]	[78,39,33,62]	-9	hSpCas9	negative selection	6415281
205121846	205121869	1	+	27260156	EW8	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.5975125598159219	[641]	[387,403,276,321]	-8	hSpCas9	negative selection	6479535
205100224	205100247	1	-	27260156	EW8	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.413519924651926	[550]	[208,128,127,214]	-9	hSpCas9	negative selection	6479536
205100165	205100188	1	-	27260156	EW8	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.15815480723979536	[1304]	[1356,922,727,862]	-3	hSpCas9	negative selection	6479537
205105026	205105049	1	+	27260156	CORL105	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.389437571250105	[413]	[351,371,443,322]	-6	hSpCas9	negative selection	6536530
205121855	205121878	1	-	27260156	CORL105	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.37582038206069135	[729]	[1203,1166,1108,957]	7	hSpCas9	negative selection	6536531
205105062	205105085	1	+	27260156	CORL105	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.035330458692694	[141]	[80,115,56,65]	-9	hSpCas9	negative selection	6536532
205121846	205121869	1	+	27260156	CORL105	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.48310662630839774	[641]	[532,535,665,435]	-7	hSpCas9	negative selection	6600786
205100224	205100247	1	-	27260156	CORL105	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.2732709002511298	[550]	[280,195,247,340]	-9	hSpCas9	negative selection	6600787
205100165	205100188	1	-	27260156	CORL105	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.5802862777120814	[1304]	[937,951,1329,913]	-8	hSpCas9	negative selection	6600788
205105026	205105049	1	+	27260156	HS294T	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.3083917761052194	[413]	[201,105,113,407]	4	hSpCas9	negative selection	6657781
205121855	205121878	1	-	27260156	HS294T	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.4425439375758109	[729]	[567,217,359,372]	6	hSpCas9	negative selection	6657782
205105062	205105085	1	+	27260156	HS294T	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.9418597834888269	[141]	[18,15,49,30]	-8	hSpCas9	negative selection	6657783
205121846	205121869	1	+	27260156	HS294T	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.004049276208571151	[641]	[142,302,221,345]	0	hSpCas9	negative selection	6722037
205100224	205100247	1	-	27260156	HS294T	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.8106050794759116	[550]	[54,21,69,104]	-9	hSpCas9	negative selection	6722038
205100165	205100188	1	-	27260156	HS294T	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.383373526481501	[1304]	[320,303,304,672]	-5	hSpCas9	negative selection	6722039
205105026	205105049	1	+	27260156	HCC44	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.046906968475529914	[413]	[785,215,484,393]	-1	hSpCas9	negative selection	6779032
205121855	205121878	1	-	27260156	HCC44	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.09511105750195048	[729]	[927,735,1054,856]	1	hSpCas9	negative selection	6779033
205105062	205105085	1	+	27260156	HCC44	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.8229738433930545	[141]	[66,95,130,72]	-8	hSpCas9	negative selection	6779034
205121846	205121869	1	+	27260156	HCC44	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.5448164306359438	[641]	[336,380,628,658]	-7	hSpCas9	negative selection	6843288
205100224	205100247	1	-	27260156	HCC44	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.9654172101745495	[550]	[185,211,85,135]	-9	hSpCas9	negative selection	6843289
205100165	205100188	1	-	27260156	HCC44	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.30414046052784904	[1304]	[1416,931,1176,1296]	-5	hSpCas9	negative selection	6843290
205105026	205105049	1	+	27260156	G402	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.11222086780143499	[413]	[634,736,246,584]	1	hSpCas9	negative selection	6900283
205121855	205121878	1	-	27260156	G402	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.5468376023707784	[729]	[1686,1554,1055,987]	6	hSpCas9	negative selection	6900284
205105062	205105085	1	+	27260156	G402	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.716065390381545	[141]	[76,58,200,78]	-7	hSpCas9	negative selection	6900285
205121846	205121869	1	+	27260156	G402	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.17145504965826	[641]	[451,252,359,334]	-8	hSpCas9	negative selection	6964539
205100224	205100247	1	-	27260156	G402	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.1791997489203094	[550]	[111,203,143,131]	-9	hSpCas9	negative selection	6964540
205100165	205100188	1	-	27260156	G402	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.16607686281701195	[1304]	[1937,1072,1610,1118]	-2	hSpCas9	negative selection	6964541
205105026	205105049	1	+	27260156	L33	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.2816879886330407	[413]	[277,179,196,332]	-6	hSpCas9	negative selection	7021534
205121855	205121878	1	-	27260156	L33	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.114273146058811	[729]	[904,281,517,740]	2	hSpCas9	negative selection	7021535
205105062	205105085	1	+	27260156	L33	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.1358806839035851	[141]	[160,60,71,91]	-3	hSpCas9	negative selection	7021536
205121846	205121869	1	+	27260156	L33	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.2601848731625302	[641]	[768,306,497,764]	5	hSpCas9	negative selection	7085790
205100224	205100247	1	-	27260156	L33	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.0276678107872488	[550]	[214,103,168,343]	-9	hSpCas9	negative selection	7085791
205100165	205100188	1	-	27260156	L33	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.3258275875817407	[1304]	[984,382,736,1073]	-6	hSpCas9	negative selection	7085792
205105026	205105049	1	+	27260156	K562	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.615147189014513	[413]	[286,159,411,113]	-6	hSpCas9	negative selection	7142785
205121855	205121878	1	-	27260156	K562	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.5690364914510451	[729]	[904,1375,960,651]	7	hSpCas9	negative selection	7142786
205105062	205105085	1	+	27260156	K562	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.4715101546968887	[141]	[13,69,66,30]	-9	hSpCas9	negative selection	7142787
205121846	205121869	1	+	27260156	K562	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.4804393559472158	[641]	[361,372,255,610]	-5	hSpCas9	negative selection	7207041
205100224	205100247	1	-	27260156	K562	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.091424167635777	[550]	[98,56,266,39]	-9	hSpCas9	negative selection	7207042
205100165	205100188	1	-	27260156	K562	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.1675919043983216	[1304]	[1328,1560,711,618]	-2	hSpCas9	negative selection	7207043
205105026	205105049	1	+	27260156	HT29	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.14361124032504546	[413]	[483,500,356,479]	-3	hSpCas9	negative selection	7264036
205121855	205121878	1	-	27260156	HT29	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.2717679508819034	[729]	[1179,1227,1139,786]	5	hSpCas9	negative selection	7264037
205105062	205105085	1	+	27260156	HT29	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.653848470185072	[141]	[44,35,65,67]	-9	hSpCas9	negative selection	7264038
205121846	205121869	1	+	27260156	HT29	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.26517879764474456	[641]	[678,567,654,681]	-5	hSpCas9	negative selection	7328292
205100224	205100247	1	-	27260156	HT29	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.46529963435495	[550]	[258,268,191,250]	-9	hSpCas9	negative selection	7328293
205100165	205100188	1	-	27260156	HT29	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.08755733077442018	[1304]	[1323,1848,1361,1448]	-2	hSpCas9	negative selection	7328294
205105026	205105049	1	+	27260156	MHHES1	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3358979366760541	[413]	[448,523,236,299]	-6	hSpCas9	negative selection	7385287
205121855	205121878	1	-	27260156	MHHES1	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.5251964287509407	[729]	[1290,1463,1143,911]	8	hSpCas9	negative selection	7385288
205105062	205105085	1	+	27260156	MHHES1	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.9632202184367225	[141]	[135,22,91,76]	-9	hSpCas9	negative selection	7385289
205121846	205121869	1	+	27260156	MHHES1	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.17015333360619356	[641]	[823,806,682,349]	-3	hSpCas9	negative selection	7449543
205100224	205100247	1	-	27260156	MHHES1	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.2665836853369825	[550]	[328,232,279,202]	-9	hSpCas9	negative selection	7449544
205100165	205100188	1	-	27260156	MHHES1	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.4341185387272606	[1304]	[1210,1217,1116,861]	-7	hSpCas9	negative selection	7449545
205105026	205105049	1	+	27260156	MEWO	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3298152743603862	[413]	[371,267,296]	-6	hSpCas9	negative selection	7506538
205121855	205121878	1	-	27260156	MEWO	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.1733098529971413	[729]	[972,674,701]	4	hSpCas9	negative selection	7506539
205105062	205105085	1	+	27260156	MEWO	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.5670643173616716	[141]	[110,115,45]	-8	hSpCas9	negative selection	7506540
205121846	205121869	1	+	27260156	MEWO	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.3023784211008546	[641]	[720,362,422]	-6	hSpCas9	negative selection	7570794
205100224	205100247	1	-	27260156	MEWO	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.5399747470123062	[550]	[218,149,170]	-9	hSpCas9	negative selection	7570795
205100165	205100188	1	-	27260156	MEWO	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.3751135409440969	[1304]	[1141,896,823]	-7	hSpCas9	negative selection	7570796
205105026	205105049	1	+	27260156	LNCAPCLONEFGC	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.3970511764540819	[413]	[251,308,351,234]	-6	hSpCas9	negative selection	7627789
205121855	205121878	1	-	27260156	LNCAPCLONEFGC	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.30701109782708713	[729]	[889,644,872,881]	5	hSpCas9	negative selection	7627790
205105062	205105085	1	+	27260156	LNCAPCLONEFGC	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.5839037018816635	[141]	[27,26,49,68]	-9	hSpCas9	negative selection	7627791
205121846	205121869	1	+	27260156	LNCAPCLONEFGC	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.6129552855594864	[641]	[460,357,395,307]	-7	hSpCas9	negative selection	7692045
205100224	205100247	1	-	27260156	LNCAPCLONEFGC	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.5707602507023792	[550]	[215,149,152,150]	-9	hSpCas9	negative selection	7692046
205100165	205100188	1	-	27260156	LNCAPCLONEFGC	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.2443191751295306	[1304]	[928,976,1287,842]	-4	hSpCas9	negative selection	7692047
205105026	205105049	1	+	27260156	PANC0327	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.13733891653965247	[413]	[376,236,378,643]	2	hSpCas9	negative selection	7749040
205121855	205121878	1	-	27260156	PANC0327	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3613640704391484	[729]	[875,805,856,799]	5	hSpCas9	negative selection	7749041
205105062	205105085	1	+	27260156	PANC0327	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.9618996611961614	[141]	[208,16,40,9]	-8	hSpCas9	negative selection	7749042
205121846	205121869	1	+	27260156	PANC0327	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.4535110868323505	[641]	[426,565,1253,875]	6	hSpCas9	negative selection	7813296
205100224	205100247	1	-	27260156	PANC0327	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.843777404294892	[550]	[91,234,106,94]	-9	hSpCas9	negative selection	7813297
205100165	205100188	1	-	27260156	PANC0327	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.08776208232622329	[1304]	[1460,721,1138,1118]	-1	hSpCas9	negative selection	7813298
205105026	205105049	1	+	27260156	NCIH2009	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.2225149435707861	[413]	[549,612,331]	-3	hSpCas9	negative selection	7870291
205121855	205121878	1	-	27260156	NCIH2009	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3310994512185339	[729]	[1165,1381,1273]	4	hSpCas9	negative selection	7870292
205105062	205105085	1	+	27260156	NCIH2009	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.5669734957142698	[141]	[100,190,101]	-6	hSpCas9	negative selection	7870293
205121846	205121869	1	+	27260156	NCIH2009	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.2230276094703996	[641]	[380,353,416]	-8	hSpCas9	negative selection	7934547
205100224	205100247	1	-	27260156	NCIH2009	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.49179690410988	[550]	[176,97,143]	-9	hSpCas9	negative selection	7934548
205100165	205100188	1	-	27260156	NCIH2009	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.6254525328281728	[1304]	[1302,938,1329]	-7	hSpCas9	negative selection	7934549
205105026	205105049	1	+	27260156	NCIH1373	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.09625640697716148	[413]	[298,617,636,97]	1	hSpCas9	negative selection	7991542
205121855	205121878	1	-	27260156	NCIH1373	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.5594716544734621	[729]	[1126,1019,1290,366]	5	hSpCas9	negative selection	7991543
205105062	205105085	1	+	27260156	NCIH1373	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.8108963545663326	[141]	[82,70,57,40]	-7	hSpCas9	negative selection	7991544
205121846	205121869	1	+	27260156	NCIH1373	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.09651963620899684	[641]	[981,361,908,131]	-1	hSpCas9	negative selection	8055798
205100224	205100247	1	-	27260156	NCIH1373	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.0131815050879465	[550]	[35,112,194,67]	-9	hSpCas9	negative selection	8055799
205100165	205100188	1	-	27260156	NCIH1373	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.48935499649363456	[1304]	[1337,1164,800,232]	-5	hSpCas9	negative selection	8055800
205105026	205105049	1	+	27260156	PATU8902	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.41060932091054997	[413]	[344,181,103,1288]	-4	hSpCas9	negative selection	8112793
205121855	205121878	1	-	27260156	PATU8902	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.4905862375773473	[729]	[1047,1981,1274,1445]	5	hSpCas9	negative selection	8112794
205105062	205105085	1	+	27260156	PATU8902	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.4639280390219913	[141]	[8,89,129,38]	-8	hSpCas9	negative selection	8112795
205121846	205121869	1	+	27260156	PATU8902	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-1.6810437291753504	[641]	[310,461,80,314]	-8	hSpCas9	negative selection	8177049
205100224	205100247	1	-	27260156	PATU8902	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-3.1161323576984286	[550]	[137,166,28,26]	-9	hSpCas9	negative selection	8177050
205100165	205100188	1	-	27260156	PATU8902	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.29276060595462505	[1304]	[1772,1114,1402,1669]	-3	hSpCas9	negative selection	8177051
205105026	205105049	1	+	27260156	PANC1	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.09206304125865422	[413]	[352,482,294,242]	-1	hSpCas9	negative selection	8234044
205121855	205121878	1	-	27260156	PANC1	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.2911858609289868	[729]	[895,953,583,671]	5	hSpCas9	negative selection	8234045
205105062	205105085	1	+	27260156	PANC1	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.8863494859926198	[141]	[27,19,67,15]	-9	hSpCas9	negative selection	8234046
205121846	205121869	1	+	27260156	PANC1	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.5074753241822348	[641]	[454,320,506,267]	-6	hSpCas9	negative selection	8298300
205100224	205100247	1	-	27260156	PANC1	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.280966817961464	[550]	[128,106,69,84]	-9	hSpCas9	negative selection	8298301
205100165	205100188	1	-	27260156	PANC1	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.21352629015186975	[1304]	[828,1242,1006,850]	-3	hSpCas9	negative selection	8298302
205105026	205105049	1	+	27260156	PANC0813	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.14290384247051138	[413]	[531,805,373,438]	2	hSpCas9	negative selection	8355295
205121855	205121878	1	-	27260156	PANC0813	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3895973452214434	[729]	[1158,1035,1226,1075]	6	hSpCas9	negative selection	8355296
205105062	205105085	1	+	27260156	PANC0813	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.9019949880946816	[141]	[144,48,43,121]	-8	hSpCas9	negative selection	8355297
205121846	205121869	1	+	27260156	PANC0813	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.07461768430453941	[641]	[631,621,948,656]	-1	hSpCas9	negative selection	8419551
205100224	205100247	1	-	27260156	PANC0813	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-2.1048776524668704	[550]	[189,131,163,120]	-9	hSpCas9	negative selection	8419552
205100165	205100188	1	-	27260156	PANC0813	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.7353716222096824	[1304]	[1029,860,1197,620]	-8	hSpCas9	negative selection	8419553
205105026	205105049	1	+	27260156	RDES	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.38598224640080575	[413]	[338,280,417,433]	-6	hSpCas9	negative selection	8476546
205121855	205121878	1	-	27260156	RDES	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.46143638127234987	[729]	[968,1092,1225,1383]	7	hSpCas9	negative selection	8476547
205105062	205105085	1	+	27260156	RDES	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.6652263486245957	[141]	[90,164,90,48]	-8	hSpCas9	negative selection	8476548
205121846	205121869	1	+	27260156	RDES	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.4591730415247948	[641]	[429,504,582,660]	-7	hSpCas9	negative selection	8540802
205100224	205100247	1	-	27260156	RDES	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.6069367705122197	[550]	[168,188,173,319]	-9	hSpCas9	negative selection	8540803
205100165	205100188	1	-	27260156	RDES	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.26121887216902606	[1304]	[1056,1023,1520,1477]	-4	hSpCas9	negative selection	8540804
205105026	205105049	1	+	27260156	PC3	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.17275221866177204	[413]	[107,391,614,546]	-4	hSpCas9	negative selection	8597797
205121855	205121878	1	-	27260156	PC3	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.1293043177623786	[729]	[516,708,1356,869]	3	hSpCas9	negative selection	8597798
205105062	205105085	1	+	27260156	PC3	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.2394267828687	[141]	[102,138,148,88]	-5	hSpCas9	negative selection	8597799
205121846	205121869	1	+	27260156	PC3	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.08097584242589034	[641]	[383,743,862,554]	-2	hSpCas9	negative selection	8662053
205100224	205100247	1	-	27260156	PC3	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-0.7192282310565999	[550]	[120,366,563,447]	-9	hSpCas9	negative selection	8662054
205100165	205100188	1	-	27260156	PC3	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.22565523775710639	[1304]	[743,964,2194,1019]	-5	hSpCas9	negative selection	8662055
205105026	205105049	1	+	27260156	PATU8988T	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.30243777428155316	[413]	[235,256,394,408]	-5	hSpCas9	negative selection	8719048
205121855	205121878	1	-	27260156	PATU8988T	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.24191365687722977	[729]	[798,739,943,843]	4	hSpCas9	negative selection	8719049
205105062	205105085	1	+	27260156	PATU8988T	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.2659099165116623	[141]	[139,92,112,107]	-4	hSpCas9	negative selection	8719050
205121846	205121869	1	+	27260156	PATU8988T	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.45876879959640254	[641]	[264,460,605,473]	-6	hSpCas9	negative selection	8783304
205100224	205100247	1	-	27260156	PATU8988T	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.5500091623659147	[550]	[253,103,199,159]	-9	hSpCas9	negative selection	8783305
205100165	205100188	1	-	27260156	PATU8988T	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.46137847406695554	[1304]	[915,859,812,1083]	-6	hSpCas9	negative selection	8783306
205105026	205105049	1	+	27260156	T47D	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.0874366849849692	[413]	[384,454,462,513]	-2	hSpCas9	negative selection	8840299
205121855	205121878	1	-	27260156	T47D	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.21574291408026636	[729]	[1134,872,946,1006]	4	hSpCas9	negative selection	8840300
205105062	205105085	1	+	27260156	T47D	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.7937844890987658	[141]	[123,56,106,96]	-9	hSpCas9	negative selection	8840301
205121846	205121869	1	+	27260156	T47D	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.4548844386851681	[641]	[491,515,598,577]	-7	hSpCas9	negative selection	8904555
205100224	205100247	1	-	27260156	T47D	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.261619968399314	[550]	[288,269,204,308]	-9	hSpCas9	negative selection	8904556
205100165	205100188	1	-	27260156	T47D	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.05698602351651538	[1304]	[1650,1306,1496,1401]	-1	hSpCas9	negative selection	8904557
205105026	205105049	1	+	27260156	SU8686	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	0.19641828221596652	[413]	[396,387,526,608]	3	hSpCas9	negative selection	8961550
205121855	205121878	1	-	27260156	SU8686	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.28626525926850055	[729]	[736,864,849,1129]	5	hSpCas9	negative selection	8961551
205105062	205105085	1	+	27260156	SU8686	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-1.0269637373213933	[141]	[59,53,62,107]	-8	hSpCas9	negative selection	8961552
205121846	205121869	1	+	27260156	SU8686	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	0.11379183573371349	[641]	[588,495,714,1044]	2	hSpCas9	negative selection	9025806
205100224	205100247	1	-	27260156	SU8686	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.7996123960555643	[550]	[198,129,142,151]	-9	hSpCas9	negative selection	9025807
205100165	205100188	1	-	27260156	SU8686	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.6712034926943932	[1304]	[724,799,799,952]	-7	hSpCas9	negative selection	9025808
205105026	205105049	1	+	27260156	SKES1	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.6361506194293027	[413]	[289,237,275,256]	-8	hSpCas9	negative selection	9082801
205121855	205121878	1	-	27260156	SKES1	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.25206749808668727	[729]	[1243,984,623,696]	5	hSpCas9	negative selection	9082802
205105062	205105085	1	+	27260156	SKES1	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	0.040739188168067875	[141]	[225,150,153,70]	0	hSpCas9	negative selection	9082803
205121846	205121869	1	+	27260156	SKES1	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.36854503697183744	[641]	[501,552,442,489]	-7	hSpCas9	negative selection	9147057
205100224	205100247	1	-	27260156	SKES1	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-0.9320880070100926	[550]	[307,421,183,258]	-9	hSpCas9	negative selection	9147058
205100165	205100188	1	-	27260156	SKES1	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.23927176463270716	[1304]	[1309,1274,1154,750]	-5	hSpCas9	negative selection	9147059
205105026	205105049	1	+	27260156	TOV112D	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.48211174738334245	[413]	[221,439,334,220]	-7	hSpCas9	negative selection	9204052
205121855	205121878	1	-	27260156	TOV112D	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.330091053931989	[729]	[1104,750,976,818]	6	hSpCas9	negative selection	9204053
205105062	205105085	1	+	27260156	TOV112D	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.23571903490668022	[141]	[113,180,74,126]	-4	hSpCas9	negative selection	9204054
205121846	205121869	1	+	27260156	TOV112D	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.12495905687667602	[641]	[555,848,510,504]	-2	hSpCas9	negative selection	9268308
205100224	205100247	1	-	27260156	TOV112D	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.0489834656231571	[550]	[186,221,274,361]	-9	hSpCas9	negative selection	9268309
205100165	205100188	1	-	27260156	TOV112D	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.36389442311719966	[1304]	[1304,1063,1105,632]	-6	hSpCas9	negative selection	9268310
205105026	205105049	1	+	27260156	TC71	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.00857998207104177	[413]	[400,481,425,457]	0	hSpCas9	negative selection	9325303
205121855	205121878	1	-	27260156	TC71	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.21369434820743038	[729]	[806,939,902,986]	5	hSpCas9	negative selection	9325304
205105062	205105085	1	+	27260156	TC71	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.12126238322522132	[141]	[116,84,163,196]	-3	hSpCas9	negative selection	9325305
205121846	205121869	1	+	27260156	TC71	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.014178047238522284	[641]	[553,693,644,846]	0	hSpCas9	negative selection	9389559
205100224	205100247	1	-	27260156	TC71	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-0.6202404634077531	[550]	[370,398,375,391]	-9	hSpCas9	negative selection	9389560
205100165	205100188	1	-	27260156	TC71	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.14567766993318565	[1304]	[1296,1161,1192,1416]	-4	hSpCas9	negative selection	9389561
205105026	205105049	1	+	27260156	TC32	viability	ACTGATCTCGTGGATGATATTGG	RBBP5	ENSG00000117222	-0.6073803029702476	[413]	[288,212,303,216]	-8	hSpCas9	negative selection	9446554
205121855	205121878	1	-	27260156	TC32	viability	AGGGATGAACCTCGAGTTGCTGG	RBBP5	ENSG00000117222	0.3402122038754153	[729]	[854,625,1003,1064]	6	hSpCas9	negative selection	9446555
205105062	205105085	1	+	27260156	TC32	viability	GTGAAGGGAATCGAAACCTCTGG	RBBP5	ENSG00000117222	-0.7611781682083547	[141]	[64,7,192,94]	-9	hSpCas9	negative selection	9446556
205121846	205121869	1	+	27260156	TC32	viability	CCTTCTCACCCAGCAACTCGAGG	RBBP5	ENSG00000117222	-0.6214591652203874	[641]	[463,163,575,455]	-8	hSpCas9	negative selection	9510810
205100224	205100247	1	-	27260156	TC32	viability	CGAATAATCAGAGTTTATGATGG	RBBP5	ENSG00000117222	-1.25301402114065	[550]	[216,191,265,196]	-9	hSpCas9	negative selection	9510811
205100165	205100188	1	-	27260156	TC32	viability	TGAACCTATGCAGAAATTGCAGG	RBBP5	ENSG00000117222	-0.2038861317313998	[1304]	[1258,712,1207,1151]	-4	hSpCas9	negative selection	9510812
205099925	205099948	1	+	27869803	HPAFII	viability after 27 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-1.632545163881067	[88]	[7,20,NaN]	-8	hSpCas9	negative selection	9531618
205101603	205101626	1	-	27869803	HPAFII	viability after 27 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.5367015051501869	[392]	[344,261,NaN]	4	hSpCas9	negative selection	9531619
205103937	205103960	1	-	27869803	HPAFII	viability after 27 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.806026127700588	[90]	[58,0,NaN]	-5	hSpCas9	negative selection	9531620
205105078	205105101	1	-	27869803	HPAFII	viability after 27 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-5.3295126901153544	[444]	[1,8,NaN]	-9	hSpCas9	negative selection	9531621
205114902	205114925	1	-	27869803	HPAFII	viability after 27 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-4.046424337091352	[279]	[15,2,NaN]	-9	hSpCas9	negative selection	9531622
205115858	205115881	1	+	27869803	HPAFII	viability after 27 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.6248014800876813	[181]	[218,87,NaN]	5	hSpCas9	negative selection	9531623
205099925	205099948	1	+	27869803	HPAFII	viability after 15 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.4586776648038733	[88]	[76,64,NaN]	-5	hSpCas9	negative selection	9614067
205101603	205101626	1	-	27869803	HPAFII	viability after 15 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.490280526589266	[392]	[863,424,NaN]	5	hSpCas9	negative selection	9614068
205103937	205103960	1	-	27869803	HPAFII	viability after 15 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.8328211239955716	[90]	[69,0,NaN]	-9	hSpCas9	negative selection	9614069
205105078	205105101	1	-	27869803	HPAFII	viability after 15 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-4.980373096492274	[444]	[16,13,NaN]	-9	hSpCas9	negative selection	9614070
205114902	205114925	1	-	27869803	HPAFII	viability after 15 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.1528587718313352	[279]	[159,119,NaN]	-8	hSpCas9	negative selection	9614071
205115858	205115881	1	+	27869803	HPAFII	viability after 15 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	-0.05624486348825575	[181]	[242,153,NaN]	0	hSpCas9	negative selection	9614072
205099925	205099948	1	+	27869803	ASPC1	viability after 36 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	0.43838669661140717	[321]	[265,150,71]	4	hSpCas9	negative selection	9696516
205101603	205101626	1	-	27869803	ASPC1	viability after 36 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.3739017422443134	[1343]	[852,832,250]	4	hSpCas9	negative selection	9696517
205103937	205103960	1	-	27869803	ASPC1	viability after 36 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.3637927324184655	[360]	[38,46,56]	-8	hSpCas9	negative selection	9696518
205105078	205105101	1	-	27869803	ASPC1	viability after 36 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.8517314302454633	[1051]	[163,102,55]	-9	hSpCas9	negative selection	9696519
205114902	205114925	1	-	27869803	ASPC1	viability after 36 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.03490619208470569	[876]	[620,150,186]	0	hSpCas9	negative selection	9696520
205115858	205115881	1	+	27869803	ASPC1	viability after 36 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.09705912980297643	[447]	[47,232,196]	0	hSpCas9	negative selection	9696521
205099925	205099948	1	+	27869803	PATU8988S	viability after 35 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-1.142750978962171	[265]	[56,39,NaN]	-8	hSpCas9	negative selection	9778965
205101603	205101626	1	-	27869803	PATU8988S	viability after 35 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	-0.149962378697447	[971]	[494,209,NaN]	-1	hSpCas9	negative selection	9778966
205103937	205103960	1	-	27869803	PATU8988S	viability after 35 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.002117787068607213	[322]	[84,174,NaN]	0	hSpCas9	negative selection	9778967
205105078	205105101	1	-	27869803	PATU8988S	viability after 35 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.176538178509336	[784]	[41,97,NaN]	-9	hSpCas9	negative selection	9778968
205114902	205114925	1	-	27869803	PATU8988S	viability after 35 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.443566414697155	[664]	[84,111,NaN]	-8	hSpCas9	negative selection	9778969
205115858	205115881	1	+	27869803	PATU8988S	viability after 35 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.7046151700670935	[393]	[305,210,NaN]	7	hSpCas9	negative selection	9778970
205099925	205099948	1	+	27869803	PATU8988S	viability after 31 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-0.8237250509055802	[265]	[84,27,NaN]	-7	hSpCas9	negative selection	9861414
205101603	205101626	1	-	27869803	PATU8988S	viability after 31 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.1013313978082877	[971]	[512,291,NaN]	1	hSpCas9	negative selection	9861415
205103937	205103960	1	-	27869803	PATU8988S	viability after 31 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.8870901396815329	[322]	[66,72,NaN]	-7	hSpCas9	negative selection	9861416
205105078	205105101	1	-	27869803	PATU8988S	viability after 31 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.215472919923524	[784]	[51,86,NaN]	-9	hSpCas9	negative selection	9861417
205114902	205114925	1	-	27869803	PATU8988S	viability after 31 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.4980873097284426	[664]	[130,259,NaN]	-5	hSpCas9	negative selection	9861418
205115858	205115881	1	+	27869803	PATU8988S	viability after 31 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.6896700120049829	[393]	[237,272,NaN]	7	hSpCas9	negative selection	9861419
205099925	205099948	1	+	27869803	HPAFII	viability after 35 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-2.4112223179874848	[88]	[7,8,NaN]	-8	hSpCas9	negative selection	9943863
205101603	205101626	1	-	27869803	HPAFII	viability after 35 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.5948767901372878	[392]	[339,255,NaN]	4	hSpCas9	negative selection	9943864
205103937	205103960	1	-	27869803	HPAFII	viability after 35 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.05221689884606162	[90]	[82,0,NaN]	0	hSpCas9	negative selection	9943865
205105078	205105101	1	-	27869803	HPAFII	viability after 35 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-7.2594077364433645	[444]	[0,1,NaN]	-9	hSpCas9	negative selection	9943866
205114902	205114925	1	-	27869803	HPAFII	viability after 35 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-6.5910292275345705	[279]	[0,1,NaN]	-9	hSpCas9	negative selection	9943867
205115858	205115881	1	+	27869803	HPAFII	viability after 35 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	1.0763508912549469	[181]	[301,72,NaN]	7	hSpCas9	negative selection	9943868
205099925	205099948	1	+	27869803	HPAFII	viability after 31 days	GGAGTTCTCCTCTCGTCCCATGG	RBBP5	ENSG00000117222	-1.3235289428266432	[88]	[18,20,NaN]	-7	hSpCas9	negative selection	10026312
205101603	205101626	1	-	27869803	HPAFII	viability after 31 days	TCAATTGAGTTTGCCCGGAAGGG	RBBP5	ENSG00000117222	0.7029692472846742	[392]	[370,345,NaN]	5	hSpCas9	negative selection	10026313
205103937	205103960	1	-	27869803	HPAFII	viability after 31 days	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.15321414725268268	[90]	[107,0,NaN]	1	hSpCas9	negative selection	10026314
205105078	205105101	1	-	27869803	HPAFII	viability after 31 days	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-6.679945414099297	[444]	[0,3,NaN]	-9	hSpCas9	negative selection	10026315
205114902	205114925	1	-	27869803	HPAFII	viability after 31 days	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-3.1719382544335213	[279]	[15,18,NaN]	-9	hSpCas9	negative selection	10026316
205115858	205115881	1	+	27869803	HPAFII	viability after 31 days	CTCTGGATAGTTCTGCCCAAAGG	RBBP5	ENSG00000117222	0.6177009545941193	[181]	[239,65,NaN]	4	hSpCas9	negative selection	10026317
205096801	205096824	1	+	28162770	P31FUJ	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.2776564401986388	[391]	[94]	-8	hSpCas9	negative selection	10222793
205103937	205103960	1	-	28162770	P31FUJ	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.9718421268184435	[231]	[138]	-6	hSpCas9	negative selection	10222794
205096764	205096787	1	-	28162770	P31FUJ	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.10247033606669845	[274]	[300]	-1	hSpCas9	negative selection	10222795
205100015	205100038	1	-	28162770	P31FUJ	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-4.31495124576825	[270]	[15]	-9	hSpCas9	negative selection	10222796
205115857	205115880	1	-	28162770	P31FUJ	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.7996173584252757	[473]	[79]	-9	hSpCas9	negative selection	10222797
205114902	205114925	1	-	28162770	P31FUJ	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	1.2195608305532855	[185]	[508]	9	hSpCas9	negative selection	10222798
205103891	205103914	1	-	28162770	P31FUJ	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.6504741892839386	[385]	[711]	7	hSpCas9	negative selection	10222799
205101599	205101622	1	-	28162770	P31FUJ	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.14888803767602798	[557]	[726]	1	hSpCas9	negative selection	10222800
205105108	205105131	1	-	28162770	P31FUJ	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-1.0296392545579833	[204]	[117]	-6	hSpCas9	negative selection	10222801
205105078	205105101	1	-	28162770	P31FUJ	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-3.284890715562833	[140]	[16]	-9	hSpCas9	negative selection	10222802
205096801	205096824	1	+	28162770	TF1	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	NaN	[NaN]	[202]	1	hSpCas9	negative selection	10392159
205103937	205103960	1	-	28162770	TF1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10392160
205096764	205096787	1	-	28162770	TF1	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10392161
205100015	205100038	1	-	28162770	TF1	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10392162
205115857	205115880	1	-	28162770	TF1	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10392163
205114902	205114925	1	-	28162770	TF1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10392164
205103891	205103914	1	-	28162770	TF1	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	NaN	[NaN]	[297]	1	hSpCas9	negative selection	10392165
205101599	205101622	1	-	28162770	TF1	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	NaN	[NaN]	[246]	1	hSpCas9	negative selection	10392166
205105108	205105131	1	-	28162770	TF1	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10392167
205105078	205105101	1	-	28162770	TF1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10392168
205096801	205096824	1	+	28162770	SKM1	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.5833907661274293	[138]	[81]	-8	hSpCas9	negative selection	10561525
205103937	205103960	1	-	28162770	SKM1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.3993106261997264	[46]	[62]	-3	hSpCas9	negative selection	10561526
205096764	205096787	1	-	28162770	SKM1	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.41261076188430373	[63]	[84]	-3	hSpCas9	negative selection	10561527
205100015	205100038	1	-	28162770	SKM1	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-1.2625742894079868	[56]	[41]	-7	hSpCas9	negative selection	10561528
205115857	205115880	1	-	28162770	SKM1	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.880895387075574	[124]	[29]	-9	hSpCas9	negative selection	10561529
205114902	205114925	1	-	28162770	SKM1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.28563902516596423	[70]	[152]	2	hSpCas9	negative selection	10561530
205103891	205103914	1	-	28162770	SKM1	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.5219527031953556	[103]	[263]	5	hSpCas9	negative selection	10561531
205101599	205101622	1	-	28162770	SKM1	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.024752041682312598	[128]	[231]	0	hSpCas9	negative selection	10561532
205105108	205105131	1	-	28162770	SKM1	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.6062730069665685	[30]	[8]	-9	hSpCas9	negative selection	10561533
205105078	205105101	1	-	28162770	SKM1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.5589672921882118	[24]	[14]	-8	hSpCas9	negative selection	10561534
205096801	205096824	1	+	28162770	SKM1	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.5833907661274293	[138]	[81]	-8	hSpCas9	negative selection	10730891
205103937	205103960	1	-	28162770	SKM1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.3993106261997264	[46]	[62]	-3	hSpCas9	negative selection	10730892
205096764	205096787	1	-	28162770	SKM1	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.41261076188430373	[63]	[84]	-3	hSpCas9	negative selection	10730893
205100015	205100038	1	-	28162770	SKM1	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-1.2625742894079868	[56]	[41]	-7	hSpCas9	negative selection	10730894
205115857	205115880	1	-	28162770	SKM1	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.880895387075574	[124]	[29]	-9	hSpCas9	negative selection	10730895
205114902	205114925	1	-	28162770	SKM1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.28563902516596423	[70]	[152]	2	hSpCas9	negative selection	10730896
205103891	205103914	1	-	28162770	SKM1	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.5219527031953556	[103]	[263]	5	hSpCas9	negative selection	10730897
205101599	205101622	1	-	28162770	SKM1	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.024752041682312598	[128]	[231]	0	hSpCas9	negative selection	10730898
205105108	205105131	1	-	28162770	SKM1	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.6062730069665685	[30]	[8]	-9	hSpCas9	negative selection	10730899
205105078	205105101	1	-	28162770	SKM1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.5589672921882118	[24]	[14]	-8	hSpCas9	negative selection	10730900
205096801	205096824	1	+	28162770	PL21	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.0429033161570076	[515]	[108]	-6	hSpCas9	negative selection	10900257
205103937	205103960	1	-	28162770	PL21	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	0.1925663947845193	[190]	[94]	1	hSpCas9	negative selection	10900258
205096764	205096787	1	-	28162770	PL21	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	0.0936886728586776	[238]	[110]	0	hSpCas9	negative selection	10900259
205100015	205100038	1	-	28162770	PL21	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-2.5743006850955488	[259]	[18]	-9	hSpCas9	negative selection	10900260
205115857	205115880	1	-	28162770	PL21	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-1.773318598058188	[376]	[47]	-8	hSpCas9	negative selection	10900261
205114902	205114925	1	-	28162770	PL21	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.6400517824071933	[229]	[155]	5	hSpCas9	negative selection	10900262
205103891	205103914	1	-	28162770	PL21	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.9309529816739308	[281]	[233]	7	hSpCas9	negative selection	10900263
205101599	205101622	1	-	28162770	PL21	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.041282850003207416	[421]	[188]	0	hSpCas9	negative selection	10900264
205105108	205105131	1	-	28162770	PL21	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-0.331874006282877	[106]	[36]	-2	hSpCas9	negative selection	10900265
205105078	205105101	1	-	28162770	PL21	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.429910775760374	[129]	[20]	-7	hSpCas9	negative selection	10900266
205096801	205096824	1	+	28162770	P31FUJ	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.2776564401986388	[391]	[94]	-8	hSpCas9	negative selection	11069623
205103937	205103960	1	-	28162770	P31FUJ	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.9718421268184435	[231]	[138]	-6	hSpCas9	negative selection	11069624
205096764	205096787	1	-	28162770	P31FUJ	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.10247033606669845	[274]	[300]	-1	hSpCas9	negative selection	11069625
205100015	205100038	1	-	28162770	P31FUJ	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-4.31495124576825	[270]	[15]	-9	hSpCas9	negative selection	11069626
205115857	205115880	1	-	28162770	P31FUJ	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.7996173584252757	[473]	[79]	-9	hSpCas9	negative selection	11069627
205114902	205114925	1	-	28162770	P31FUJ	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	1.2195608305532855	[185]	[508]	9	hSpCas9	negative selection	11069628
205103891	205103914	1	-	28162770	P31FUJ	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.6504741892839386	[385]	[711]	7	hSpCas9	negative selection	11069629
205101599	205101622	1	-	28162770	P31FUJ	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.14888803767602798	[557]	[726]	1	hSpCas9	negative selection	11069630
205105108	205105131	1	-	28162770	P31FUJ	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-1.0296392545579833	[204]	[117]	-6	hSpCas9	negative selection	11069631
205105078	205105101	1	-	28162770	P31FUJ	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-3.284890715562833	[140]	[16]	-9	hSpCas9	negative selection	11069632
205096801	205096824	1	+	28162770	OCIAML5	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.2502302515784445	[339]	[128]	-8	hSpCas9	negative selection	11238989
205103937	205103960	1	-	28162770	OCIAML5	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.999408286939184	[102]	[92]	-6	hSpCas9	negative selection	11238990
205096764	205096787	1	-	28162770	OCIAML5	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-1.0721150517321458	[204]	[175]	-6	hSpCas9	negative selection	11238991
205100015	205100038	1	-	28162770	OCIAML5	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-4.5525062890050885	[129]	[9]	-9	hSpCas9	negative selection	11238992
205115857	205115880	1	-	28162770	OCIAML5	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-3.5344948810207706	[198]	[30]	-9	hSpCas9	negative selection	11238993
205114902	205114925	1	-	28162770	OCIAML5	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.8636578757280389	[129]	[426]	7	hSpCas9	negative selection	11238994
205103891	205103914	1	-	28162770	OCIAML5	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	-0.03091465132792548	[222]	[393]	0	hSpCas9	negative selection	11238995
205101599	205101622	1	-	28162770	OCIAML5	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.6844666223679285	[275]	[309]	-4	hSpCas9	negative selection	11238996
205105108	205105131	1	-	28162770	OCIAML5	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.2554222650952056	[81]	[30]	-8	hSpCas9	negative selection	11238997
205105078	205105101	1	-	28162770	OCIAML5	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.6054266032808715	[58]	[34]	-7	hSpCas9	negative selection	11238998
205096801	205096824	1	+	28162770	EOL1	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.3097276412818353	[893]	[189]	-7	hSpCas9	negative selection	11408355
205103937	205103960	1	-	28162770	EOL1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.7740715109461888	[197]	[60]	-5	hSpCas9	negative selection	11408356
205096764	205096787	1	-	28162770	EOL1	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	0.5430754232170351	[438]	[336]	5	hSpCas9	negative selection	11408357
205100015	205100038	1	-	28162770	EOL1	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-1.798612023070641	[415]	[62]	-8	hSpCas9	negative selection	11408358
205115857	205115880	1	-	28162770	EOL1	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-1.763307610970567	[798]	[123]	-8	hSpCas9	negative selection	11408359
205114902	205114925	1	-	28162770	EOL1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.3405344629121178	[422]	[175]	-3	hSpCas9	negative selection	11408360
205103891	205103914	1	-	28162770	EOL1	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.8268279510483802	[396]	[370]	7	hSpCas9	negative selection	11408361
205101599	205101622	1	-	28162770	EOL1	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.4063691065440826	[482]	[191]	-3	hSpCas9	negative selection	11408362
205105108	205105131	1	-	28162770	EOL1	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-1.271003037547272	[141]	[30]	-7	hSpCas9	negative selection	11408363
205105078	205105101	1	-	28162770	EOL1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-3.093374136426728	[161]	[9]	-9	hSpCas9	negative selection	11408364
205096801	205096824	1	+	28162770	MOLM13	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.3117205500301212	[720]	[209]	-6	hSpCas9	negative selection	11577721
205103937	205103960	1	-	28162770	MOLM13	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.9726832098414024	[189]	[34]	-7	hSpCas9	negative selection	11577722
205096764	205096787	1	-	28162770	MOLM13	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-2.307756680785687	[314]	[45]	-8	hSpCas9	negative selection	11577723
205100015	205100038	1	-	28162770	MOLM13	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-3.4909532936986616	[310]	[19]	-8	hSpCas9	negative selection	11577724
205115857	205115880	1	-	28162770	MOLM13	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-4.671059969993867	[598]	[16]	-9	hSpCas9	negative selection	11577725
205114902	205114925	1	-	28162770	MOLM13	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.4441629191797185	[349]	[185]	-3	hSpCas9	negative selection	11577726
205103891	205103914	1	-	28162770	MOLM13	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	-0.32821133670895974	[414]	[238]	-2	hSpCas9	negative selection	11577727
205101599	205101622	1	-	28162770	MOLM13	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-1.1504317161230082	[524]	[170]	-6	hSpCas9	negative selection	11577728
205105108	205105131	1	-	28162770	MOLM13	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-3.7451043417896197	[203]	[10]	-9	hSpCas9	negative selection	11577729
205105078	205105101	1	-	28162770	MOLM13	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-6.6195734597057605	[135]	[0]	-9	hSpCas9	negative selection	11577730
205096801	205096824	1	+	28162770	HEL	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.10375525399275	[556]	[82]	-8	hSpCas9	negative selection	11747087
205103937	205103960	1	-	28162770	HEL	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.9422236687207993	[182]	[60]	-5	hSpCas9	negative selection	11747088
205096764	205096787	1	-	28162770	HEL	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-1.5652330735899198	[364]	[78]	-7	hSpCas9	negative selection	11747089
205100015	205100038	1	-	28162770	HEL	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-3.600117691895807	[283]	[14]	-9	hSpCas9	negative selection	11747090
205115857	205115880	1	-	28162770	HEL	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-3.0551764847251883	[570]	[43]	-8	hSpCas9	negative selection	11747091
205114902	205114925	1	-	28162770	HEL	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-1.328692015802872	[399]	[101]	-6	hSpCas9	negative selection	11747092
205103891	205103914	1	-	28162770	HEL	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.4783520140994744	[324]	[289]	4	hSpCas9	negative selection	11747093
205101599	205101622	1	-	28162770	HEL	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.9671520650166532	[466]	[152]	-5	hSpCas9	negative selection	11747094
205105108	205105131	1	-	28162770	HEL	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.723583382245459	[164]	[15]	-8	hSpCas9	negative selection	11747095
205105078	205105101	1	-	28162770	HEL	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-6.368488423422897	[128]	[0]	-9	hSpCas9	negative selection	11747096
205096801	205096824	1	+	28162770	MV411	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.0802883886426997	[373]	[148]	-6	hSpCas9	negative selection	11916453
205103937	205103960	1	-	28162770	MV411	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-0.9838879953236803	[161]	[68]	-6	hSpCas9	negative selection	11916454
205096764	205096787	1	-	28162770	MV411	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-1.6490578734633647	[241]	[64]	-7	hSpCas9	negative selection	11916455
205100015	205100038	1	-	28162770	MV411	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-1.3162301715751528	[268]	[90]	-7	hSpCas9	negative selection	11916456
205115857	205115880	1	-	28162770	MV411	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.034023952597657	[456]	[93]	-8	hSpCas9	negative selection	11916457
205114902	205114925	1	-	28162770	MV411	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.09557026222341514	[292]	[230]	0	hSpCas9	negative selection	11916458
205103891	205103914	1	-	28162770	MV411	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.3898818158029807	[211]	[233]	3	hSpCas9	negative selection	11916459
205101599	205101622	1	-	28162770	MV411	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.7525624492172247	[395]	[197]	-5	hSpCas9	negative selection	11916460
205105108	205105131	1	-	28162770	MV411	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-0.060684744579556305	[103]	[83]	0	hSpCas9	negative selection	11916461
205105078	205105101	1	-	28162770	MV411	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-1.6383914292979138	[84]	[22]	-7	hSpCas9	negative selection	11916462
205096801	205096824	1	+	28162770	MONOMAC1	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.7334694538530513	[379]	[130]	-8	hSpCas9	negative selection	12085819
205103937	205103960	1	-	28162770	MONOMAC1	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.9075302298645689	[107]	[32]	-8	hSpCas9	negative selection	12085820
205096764	205096787	1	-	28162770	MONOMAC1	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.6754002817072268	[162]	[116]	-5	hSpCas9	negative selection	12085821
205100015	205100038	1	-	28162770	MONOMAC1	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-2.1332217494621104	[198]	[51]	-9	hSpCas9	negative selection	12085822
205115857	205115880	1	-	28162770	MONOMAC1	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.151870531011419	[282]	[72]	-9	hSpCas9	negative selection	12085823
205114902	205114925	1	-	28162770	MONOMAC1	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	-0.3059712186127179	[164]	[152]	-3	hSpCas9	negative selection	12085824
205103891	205103914	1	-	28162770	MONOMAC1	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.044549139510205116	[191]	[226]	0	hSpCas9	negative selection	12085825
205101599	205101622	1	-	28162770	MONOMAC1	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-0.4375538163319198	[266]	[225]	-4	hSpCas9	negative selection	12085826
205105108	205105131	1	-	28162770	MONOMAC1	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-1.5368868499441786	[80]	[31]	-8	hSpCas9	negative selection	12085827
205105078	205105101	1	-	28162770	MONOMAC1	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.641821689732449	[48]	[8]	-9	hSpCas9	negative selection	12085828
205096801	205096824	1	+	28162770	OCIAML2	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-2.540170758495238	[84]	[80]	-8	hSpCas9	negative selection	12255185
205103937	205103960	1	-	28162770	OCIAML2	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.4933499017422445	[31]	[62]	-7	hSpCas9	negative selection	12255186
205096764	205096787	1	-	28162770	OCIAML2	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-0.733664231075955	[56]	[189]	-5	hSpCas9	negative selection	12255187
205100015	205100038	1	-	28162770	OCIAML2	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-3.4064994878224457	[43]	[22]	-9	hSpCas9	negative selection	12255188
205115857	205115880	1	-	28162770	OCIAML2	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.652468148227974	[75]	[66]	-9	hSpCas9	negative selection	12255189
205114902	205114925	1	-	28162770	OCIAML2	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.9747813230802014	[46]	[511]	8	hSpCas9	negative selection	12255190
205103891	205103914	1	-	28162770	OCIAML2	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.34699343226926993	[59]	[422]	3	hSpCas9	negative selection	12255191
205101599	205101622	1	-	28162770	OCIAML2	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	0.12693271225862846	[56]	[344]	1	hSpCas9	negative selection	12255192
205105108	205105131	1	-	28162770	OCIAML2	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-2.2168732329963783	[25]	[30]	-8	hSpCas9	negative selection	12255193
205105078	205105101	1	-	28162770	OCIAML2	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.129592907407094	[14]	[18]	-8	hSpCas9	negative selection	12255194
205096801	205096824	1	+	28162770	OCIAML3	viability	GAGGTTTGGACTGCATCCGGTGG	RBBP5	ENSG00000117222	-1.363227433494996	[97]	[114]	-7	hSpCas9	negative selection	12424551
205103937	205103960	1	-	28162770	OCIAML3	viability	CAAACATGTTGTTCTGCCGGTGG	RBBP5	ENSG00000117222	-1.2440651692672042	[50]	[64]	-7	hSpCas9	negative selection	12424552
205096764	205096787	1	-	28162770	OCIAML3	viability	GGGCTAGTTCAGAGAAGAAGAGG	RBBP5	ENSG00000117222	-2.1880152806483264	[79]	[52]	-8	hSpCas9	negative selection	12424553
205100015	205100038	1	-	28162770	OCIAML3	viability	TGGGGATGGGGAATACATCGTGG	RBBP5	ENSG00000117222	-3.664396968215561	[83]	[19]	-9	hSpCas9	negative selection	12424554
205115857	205115880	1	-	28162770	OCIAML3	viability	CTTTGGGCAGAACTATCCAGAGG	RBBP5	ENSG00000117222	-2.970383519233902	[134]	[51]	-9	hSpCas9	negative selection	12424555
205114902	205114925	1	-	28162770	OCIAML3	viability	TGACTTGCACCTTTAACAGGTGG	RBBP5	ENSG00000117222	0.03749744633402313	[60]	[188]	0	hSpCas9	negative selection	12424556
205103891	205103914	1	-	28162770	OCIAML3	viability	GTGGCATCTTTTGATAGGCGAGG	RBBP5	ENSG00000117222	0.4530606133326157	[97]	[404]	4	hSpCas9	negative selection	12424557
205101599	205101622	1	-	28162770	OCIAML3	viability	TTGAGTTTGCCCGGAAGGGGAGG	RBBP5	ENSG00000117222	-1.5570134328419614	[153]	[157]	-8	hSpCas9	negative selection	12424558
205105108	205105131	1	-	28162770	OCIAML3	viability	CTGATAACATAGTGTCACAGTGG	RBBP5	ENSG00000117222	-1.719538522408022	[47]	[43]	-8	hSpCas9	negative selection	12424559
205105078	205105101	1	-	28162770	OCIAML3	viability	TTTCAGGCGACTGTGACCAGAGG	RBBP5	ENSG00000117222	-2.5008982359326817	[29]	[15]	-9	hSpCas9	negative selection	12424560