Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6275
• Symbol: S100A4
• Description: S100 calcium binding protein A4

DataSource: http://genomecrispr.dkfz.de/#!/results/S100A4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
153544758	153544781	1	-	26472758	Jiyoye	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	-0.7448277119391766	[199]	[89]	-5	hSpCas9	negative selection	141632
153543866	153543889	1	-	26472758	Jiyoye	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	1.483124234739172	[36]	[77]	8	hSpCas9	negative selection	141633
153544750	153544773	1	+	26472758	Jiyoye	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.3729596661679604	[255]	[249]	3	hSpCas9	negative selection	141634
153544773	153544796	1	-	26472758	Jiyoye	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.29614406911712976	[458]	[424]	2	hSpCas9	negative selection	141635
153544689	153544712	1	-	26472758	Jiyoye	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	1.0647831840587956	[70]	[111]	7	hSpCas9	negative selection	141636
153544732	153544755	1	+	26472758	Jiyoye	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.29013596031565403	[153]	[141]	2	hSpCas9	negative selection	141637
153544674	153544697	1	-	26472758	Jiyoye	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.31271669930139145	[111]	[67]	-2	hSpCas9	negative selection	141638
153544654	153544677	1	-	26472758	Jiyoye	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.07014039422830264	[119]	[94]	0	hSpCas9	negative selection	141639
153543854	153543877	1	-	26472758	Jiyoye	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.03520660411891541	[87]	[67]	0	hSpCas9	negative selection	141640
153543768	153543791	1	-	26472758	Jiyoye	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.2663128456660238	[42]	[77]	7	hSpCas9	negative selection	141641
153544758	153544781	1	-	26472758	KBM7	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.11986121295831775	[721,517]	[369,261]	1	hSpCas9	negative selection	332750
153543866	153543889	1	-	26472758	KBM7	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.05279090585291013	[306,301]	[165,133]	0	hSpCas9	negative selection	332751
153544750	153544773	1	+	26472758	KBM7	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.6338575250482985	[1296,951]	[923,710]	7	hSpCas9	negative selection	332752
153544773	153544796	1	-	26472758	KBM7	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.23498385826497947	[1869,1266]	[805,898]	2	hSpCas9	negative selection	332753
153544689	153544712	1	-	26472758	KBM7	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.215681262129456	[652,503]	[185,426]	2	hSpCas9	negative selection	332754
153544732	153544755	1	+	26472758	KBM7	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.26870338630635915	[590,472]	[357,246]	3	hSpCas9	negative selection	332755
153544674	153544697	1	-	26472758	KBM7	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.46543763281336054	[518,392]	[249,331]	5	hSpCas9	negative selection	332756
153544654	153544677	1	-	26472758	KBM7	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.04497786022744807	[501,288]	[196,178]	0	hSpCas9	negative selection	332757
153543854	153543877	1	-	26472758	KBM7	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.5814649231912512	[233,274]	[135,221]	6	hSpCas9	negative selection	332758
153543768	153543791	1	-	26472758	KBM7	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.7109284048050878	[200,166]	[169,114]	7	hSpCas9	negative selection	332759
153544758	153544781	1	-	26472758	Raji	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.6563478378573586	[256]	[93]	6	hSpCas9	negative selection	523868
153543866	153543889	1	-	26472758	Raji	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.5928103625438412	[119]	[41]	5	hSpCas9	negative selection	523869
153544750	153544773	1	+	26472758	Raji	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.39716279643992225	[480]	[146]	4	hSpCas9	negative selection	523870
153544773	153544796	1	-	26472758	Raji	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.4934872564076165	[553]	[180]	5	hSpCas9	negative selection	523871
153544689	153544712	1	-	26472758	Raji	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.8215657338955179	[216]	[88]	7	hSpCas9	negative selection	523872
153544732	153544755	1	+	26472758	Raji	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	-0.9188957894252494	[276]	[33]	-6	hSpCas9	negative selection	523873
153544674	153544697	1	-	26472758	Raji	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.5643837928848293	[273]	[42]	-4	hSpCas9	negative selection	523874
153544654	153544677	1	-	26472758	Raji	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.6039509201490416	[257]	[90]	6	hSpCas9	negative selection	523875
153543854	153543877	1	-	26472758	Raji	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.8374749104339394	[153]	[19]	-6	hSpCas9	negative selection	523876
153543768	153543791	1	-	26472758	Raji	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	-0.4128732759597413	[108]	[18]	-3	hSpCas9	negative selection	523877
153544758	153544781	1	-	26472758	K562	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.02768394119192491	[508]	[437]	0	hSpCas9	negative selection	714986
153543866	153543889	1	-	26472758	K562	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	1.0839540554732008	[189]	[339]	8	hSpCas9	negative selection	714987
153544750	153544773	1	+	26472758	K562	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.5458725296346651	[808]	[996]	4	hSpCas9	negative selection	714988
153544773	153544796	1	-	26472758	K562	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.37975512264520805	[1392]	[1529]	3	hSpCas9	negative selection	714989
153544689	153544712	1	-	26472758	K562	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.9361511823628004	[472]	[763]	7	hSpCas9	negative selection	714990
153544732	153544755	1	+	26472758	K562	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.8555911077104518	[399]	[610]	7	hSpCas9	negative selection	714991
153544674	153544697	1	-	26472758	K562	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	1.3073329349956981	[257]	[538]	9	hSpCas9	negative selection	714992
153544654	153544677	1	-	26472758	K562	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.5325132738174041	[304]	[177]	-3	hSpCas9	negative selection	714993
153543854	153543877	1	-	26472758	K562	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.1330044798126192	[264]	[203]	-1	hSpCas9	negative selection	714994
153543768	153543791	1	-	26472758	K562	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.959689250733334	[133]	[439]	9	hSpCas9	negative selection	714995
153544773	153544796	1	-	26627737	DLD1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.11896363129794285	[417]	[127,195,50]	-1	hSpCas9	negative selection	766089
153544773	153544796	1	-	26627737	GBM cells	viability after 5 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.17174067867809995	[271]	[113,144]	-3	hSpCas9	negative selection	848404
153544773	153544796	1	-	26627737	GBM cells	viability after 13 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.2494534449645423	[271]	[143,107]	-3	hSpCas9	negative selection	930719
153544773	153544796	1	-	26627737	GBM cells	viability after 21 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.03075162023752971	[271]	[140,147]	0	hSpCas9	negative selection	1013034
153544773	153544796	1	-	26627737	RPE1	viability after 9 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.3780241574147588	[704]	[202,394]	2	hSpCas9	negative selection	1095349
153544773	153544796	1	-	26627737	RPE1	viability after 12 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.2619066100125375	[704]	[213,240]	1	hSpCas9	negative selection	1177664
153544773	153544796	1	-	26627737	RPE1	viability after 15 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.061352389061449006	[704]	[230,185]	0	hSpCas9	negative selection	1259979
153544773	153544796	1	-	26627737	RPE1	viability after 18 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.5697754064389072	[704]	[293,269]	3	hSpCas9	negative selection	1342294
153544773	153544796	1	-	26627737	HeLa	viability after 8 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.03399161574783782	[318]	[142,162,121]	0	hSpCas9	negative selection	1424609
153544773	153544796	1	-	26627737	HeLa	viability after 12 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.18051119070757865	[318]	[96,136,213]	1	hSpCas9	negative selection	1506924
153544773	153544796	1	-	26627737	HeLa	viability after 15 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.2929957797728115	[318]	[125,237,109]	2	hSpCas9	negative selection	1589239
153544773	153544796	1	-	26627737	HeLa	viability after 18 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.2827133271253499	[318]	[83,194,109]	2	hSpCas9	negative selection	1671554
153544773	153544796	1	-	26627737	HCT116	viability after 6 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.7404220889050199	[500]	[235,73]	4	hSpCas9	negative selection	1753869
153544773	153544796	1	-	26627737	HCT116	viability after 8 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.11050174165557936	[301]	[167,167,126]	-1	hSpCas9	negative selection	1836184
153544773	153544796	1	-	26627737	HCT116	viability after 9 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.9600898567567941	[500]	[295,231]	6	hSpCas9	negative selection	1918499
153544773	153544796	1	-	26627737	HCT116	viability after 12 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.12062932650406911	[301]	[183,145,185]	1	hSpCas9	negative selection	2000814
153544773	153544796	1	-	26627737	HCT116	viability after 15 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.20201142542749267	[301]	[138,169,141]	-2	hSpCas9	negative selection	2083129
153544773	153544796	1	-	26627737	HCT116	viability after 18 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.45380359300482487	[301]	[162,222,212]	4	hSpCas9	negative selection	2165444
153544674	153544697	1	-	24336569	HL60	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.9159144753458985	[953]	[1069]	-7	hSpCas9	negative selection	2293600
153544689	153544712	1	-	24336569	HL60	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.010783289750166958	[706]	[1484]	0	hSpCas9	negative selection	2293601
153544724	153544747	1	-	24336569	HL60	viability	CACAAGTACTCGGGCAAAGAGGG	S100A4	ENSG00000196154	-0.7678180040185226	[1152]	[1432]	-6	hSpCas9	negative selection	2293602
153544729	153544752	1	+	24336569	HL60	viability	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	0.0453573988431569	[418]	[914]	0	hSpCas9	negative selection	2293603
153544734	153544757	1	-	24336569	HL60	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	2.639165265362578	[130]	[1726]	9	hSpCas9	negative selection	2293604
153544749	153544772	1	+	24336569	HL60	viability	AGGTGGACACCATCACATCCAGG	S100A4	ENSG00000196154	-0.4119857809477926	[883]	[1405]	-4	hSpCas9	negative selection	2293605
153544758	153544781	1	-	24336569	HL60	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.47628610046574926	[998]	[2940]	4	hSpCas9	negative selection	2293606
153544763	153544786	1	+	24336569	HL60	viability	ACATCCAGGGCCTTCTCCAGAGG	S100A4	ENSG00000196154	0.9739222991562806	[312]	[1300]	7	hSpCas9	negative selection	2293607
153544773	153544796	1	-	24336569	HL60	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.43804984531646923	[652]	[1019]	-4	hSpCas9	negative selection	2293608
153544779	153544802	1	-	24336569	HL60	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	-0.008049419189472107	[861]	[1813]	0	hSpCas9	negative selection	2293609
153544674	153544697	1	-	24336569	KBM7	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.0288820231618383	[688]	[1841]	0	hSpCas9	negative selection	2360777
153544689	153544712	1	-	24336569	KBM7	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.15517987145604972	[769]	[1885]	-1	hSpCas9	negative selection	2360778
153544724	153544747	1	-	24336569	KBM7	viability	CACAAGTACTCGGGCAAAGAGGG	S100A4	ENSG00000196154	0.4093577543592819	[571]	[2071]	4	hSpCas9	negative selection	2360779
153544729	153544752	1	+	24336569	KBM7	viability	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	0.2673600912873248	[395]	[1299]	2	hSpCas9	negative selection	2360780
153544734	153544757	1	-	24336569	KBM7	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.30694569627720564	[292]	[645]	-3	hSpCas9	negative selection	2360781
153544749	153544772	1	+	24336569	KBM7	viability	AGGTGGACACCATCACATCCAGG	S100A4	ENSG00000196154	0.16431563195927168	[512]	[1567]	1	hSpCas9	negative selection	2360782
153544758	153544781	1	-	24336569	KBM7	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.16536856762903462	[952]	[2914]	1	hSpCas9	negative selection	2360783
153544763	153544786	1	+	24336569	KBM7	viability	ACATCCAGGGCCTTCTCCAGAGG	S100A4	ENSG00000196154	-0.8232000602019107	[348]	[537]	-6	hSpCas9	negative selection	2360784
153544773	153544796	1	-	24336569	KBM7	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.5185920313372634	[506]	[1980]	5	hSpCas9	negative selection	2360785
153544779	153544802	1	-	24336569	KBM7	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.6959889569558074	[668]	[2955]	6	hSpCas9	negative selection	2360786
153549392	153549415	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCATCATCCCAGAAGGGCGGTGG	S100A4	ENSG00000196154	-1.1303809108046607	[107,18]	[7,3]	-6	dCas9-VP64	positive selection	2431728
153549416	153549439	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCAGCCTGGGAAAACCCGAAGG	S100A4	ENSG00000196154	-1.3536235155777119	[36,63]	[1,5]	-7	dCas9-VP64	positive selection	2431729
153545941	153545964	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAACAGGAGGCTTGGTTCCACGG	S100A4	ENSG00000196154	0.5472798992894856	[135,65]	[25,38]	2	dCas9-VP64	positive selection	2451108
153545917	153545940	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGCTGGTGGAGGGTGCTGTGG	S100A4	ENSG00000196154	2.206507055892926	[8,108]	[7,117]	7	dCas9-VP64	positive selection	2451109
153545963	153545986	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTACCCACGGGTGCCCACCTGGG	S100A4	ENSG00000196154	-2.0074484970290434	[268,68]	[9,7]	-9	dCas9-VP64	positive selection	2451110
153549392	153549415	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCATCATCCCAGAAGGGCGGTGG	S100A4	ENSG00000196154	2.0582411818621846	[24,11]	[49,2]	8	dCas9-VP64	positive selection	2526983
153549416	153549439	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCAGCCTGGGAAAACCCGAAGG	S100A4	ENSG00000196154	-1.1183108272452065	[74,314]	[11,43]	-9	dCas9-VP64	positive selection	2526984
153545941	153545964	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAACAGGAGGCTTGGTTCCACGG	S100A4	ENSG00000196154	-0.12829756780871032	[114,187]	[28,59]	-1	dCas9-VP64	positive selection	2546363
153545917	153545940	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGCTGGTGGAGGGTGCTGTGG	S100A4	ENSG00000196154	0.8811129188278137	[52,67]	[14,54]	6	dCas9-VP64	positive selection	2546364
153545963	153545986	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTACCCACGGGTGCCCACCTGGG	S100A4	ENSG00000196154	-0.6334532662551668	[425,157]	[82,41]	-6	dCas9-VP64	positive selection	2546365
153544765	153544788	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	0.3110402400614227	[4,4]	[5,5]	6	hSpCas9	positive selection	3018455
153544725	153544748	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	-0.44765408376134885	[2,2]	[1,0]	-6	hSpCas9	positive selection	3018456
153544653	153544676	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	-0.09591487900277759	[3,3]	[3,2]	-1	hSpCas9	positive selection	3018457
153544751	153544774	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	-0.37932631481648216	[3,3]	[2,0]	-5	hSpCas9	positive selection	3018458
153544765	153544788	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	0.36149037781394816	[4,4]	[4,4]	6	hSpCas9	positive selection	3086313
153544725	153544748	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	0.4181970793791311	[2,2]	[3,1]	7	hSpCas9	positive selection	3086314
153544653	153544676	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	0.19486731074943878	[3,3]	[4,1]	3	hSpCas9	positive selection	3086315
153544751	153544774	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.024650398372074153	[3,3]	[2,1]	0	hSpCas9	positive selection	3086316
153543795	153543818		+	24336571	A375	resistance to PLX after 7 days	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.03816990064118886	[8,9]	[9,9]	1	hSpCas9	positive selection	3142372
153543790	153543813		-	24336571	A375	resistance to PLX after 7 days	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.4155277377560419	[8,8]	[11,12]	9	hSpCas9	positive selection	3142373
153543854	153543877		-	24336571	A375	resistance to PLX after 7 days	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.39995471327497434	[3,7]	[3,4]	-9	hSpCas9	positive selection	3142374
153544725	153544748		+	24336571	A375	resistance to PLX after 7 days	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	-0.15816505840551687	[7,6]	[7,4]	-5	hSpCas9	positive selection	3142375
153544734	153544757		-	24336571	A375	resistance to PLX after 7 days	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.11143890869246331	[20,20]	[20,16]	-3	hSpCas9	positive selection	3142376
153544779	153544802		-	24336571	A375	resistance to PLX after 7 days	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.09183906616521487	[52,55]	[57,56]	3	hSpCas9	positive selection	3142377
153543795	153543818		+	24336571	A375	resistance to PLX after 14 days	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.7977646809095498	[9,11]	[8,8]	6	hSpCas9	positive selection	3200165
153543790	153543813		-	24336571	A375	resistance to PLX after 14 days	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.5517449573037158	[9,6]	[5,4]	5	hSpCas9	positive selection	3200166
153543854	153543877		-	24336571	A375	resistance to PLX after 14 days	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.2507767987516536	[3,5]	[2,1]	2	hSpCas9	positive selection	3200167
153544725	153544748		+	24336571	A375	resistance to PLX after 14 days	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	-0.0027971497965557646	[6,7]	[2,3]	0	hSpCas9	positive selection	3200168
153544734	153544757		-	24336571	A375	resistance to PLX after 14 days	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.8633856973102599	[27,18]	[5,5]	-8	hSpCas9	positive selection	3200169
153544779	153544802		-	24336571	A375	resistance to PLX after 14 days	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.13073126548334812	[51,76]	[32,32]	1	hSpCas9	positive selection	3200170
153543795	153543818		+	24336571	A375	viability after 7 days	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	1.2552710125906743	[3]	[8,9]	9	hSpCas9	negative selection	3257958
153543790	153543813		-	24336571	A375	viability after 7 days	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.9688487042689107	[4]	[8,8]	9	hSpCas9	negative selection	3257959
153543854	153543877		-	24336571	A375	viability after 7 days	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.35327262436704954	[7]	[3,7]	-5	hSpCas9	negative selection	3257960
153544725	153544748		+	24336571	A375	viability after 7 days	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	-0.01974047220985875	[7]	[7,6]	0	hSpCas9	negative selection	3257961
153544734	153544757		-	24336571	A375	viability after 7 days	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.5346255579099881	[14]	[20,20]	7	hSpCas9	negative selection	3257962
153544779	153544802		-	24336571	A375	viability after 7 days	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.7053308183022593	[34]	[52,55]	9	hSpCas9	negative selection	3257963
153543795	153543818		+	24336571	A375	viability after 14 days	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	1.4395214661020892	[3]	[9,11]	9	hSpCas9	negative selection	3315751
153543790	153543813		-	24336571	A375	viability after 14 days	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.8728120673248014	[4]	[9,6]	9	hSpCas9	negative selection	3315752
153543854	153543877		-	24336571	A375	viability after 14 days	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5927992208024354	[7]	[3,5]	-6	hSpCas9	negative selection	3315753
153544725	153544748		+	24336571	A375	viability after 14 days	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.03893087186173394	[7]	[6,7]	0	hSpCas9	negative selection	3315754
153544734	153544757		-	24336571	A375	viability after 14 days	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.7039290442639987	[14]	[27,18]	8	hSpCas9	negative selection	3315755
153544779	153544802		-	24336571	A375	viability after 14 days	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.9737364108263633	[34]	[51,76]	9	hSpCas9	negative selection	3315756
153543795	153543818	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.8873320313860472	[282,282]	[0,0]	-6	hSpCas9	positive selection	3391034
153544734	153544757	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.4500329206350477	[208,208]	[0,0]	-3	hSpCas9	positive selection	3391035
153544689	153544712	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.10757909194115295	[141,141]	[0,0]	0	hSpCas9	positive selection	3391036
153544764	153544787	1	+	26780180	HT29	viability (Avana library 4 designs)	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	1.13829309364793	[]	[]	4	hSpCas9	negative selection	3456853
153544725	153544748	1	-	26780180	HT29	viability (Avana library 4 designs)	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	2.10814575234559	[]	[]	7	hSpCas9	negative selection	3456854
153544653	153544676	1	-	26780180	HT29	viability (Avana library 4 designs)	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	2.20267486686992	[]	[]	7	hSpCas9	negative selection	3456855
153544750	153544773	1	+	26780180	HT29	viability (Avana library 4 designs)	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	1.54791168641535	[]	[]	6	hSpCas9	negative selection	3456856
153544653	153544676	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	1.08141066224906	[]	[]	1	hSpCas9	negative selection	3555526
153544725	153544748	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	2.704118045188	[]	[]	4	hSpCas9	negative selection	3555527
153544764	153544787	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	3.66973106437426	[]	[]	6	hSpCas9	negative selection	3555528
153544750	153544773	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	2.69050115974039	[]	[]	4	hSpCas9	negative selection	3555529
153544646	153544669	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	-0.951464887393745	[]	[]	-1	hSpCas9	negative selection	3555530
153544729	153544752	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	4.04264460292312	[]	[]	6	hSpCas9	negative selection	3555531
153544653	153544676	1	-	26780180	A375	viability (Avana lentiGuide)	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	2.27970452329975	[]	[]	2	hSpCas9	negative selection	3664185
153544725	153544748	1	-	26780180	A375	viability (Avana lentiGuide)	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	-3.25917054144779	[]	[]	-6	hSpCas9	negative selection	3664186
153544764	153544787	1	+	26780180	A375	viability (Avana lentiGuide)	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	0.457630647447814	[]	[]	0	hSpCas9	negative selection	3664187
153544750	153544773	1	+	26780180	A375	viability (Avana lentiGuide)	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	-4.20488642428002	[]	[]	-7	hSpCas9	negative selection	3664188
153544646	153544669	1	+	26780180	A375	viability (Avana lentiGuide)	CCACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	-5.29371908926002	[]	[]	-8	hSpCas9	negative selection	3664189
153544729	153544752	1	+	26780180	A375	viability (Avana lentiGuide)	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	4.23729231627398	[]	[]	4	hSpCas9	negative selection	3664190
153544653	153544676	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	-0.014238798037684991	[5]	[5,4]	0	hSpCas9	positive selection	3772792
153544725	153544748	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	0.0424918971035356	[4]	[4,3]	1	hSpCas9	positive selection	3772793
153544764	153544787	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	0.1446078254125888	[5]	[7,5]	4	hSpCas9	positive selection	3772794
153544750	153544773	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.08373505871386361	[4]	[4,5]	2	hSpCas9	positive selection	3772795
153544646	153544669	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.3482139440241133	[4]	[5,4]	9	hSpCas9	positive selection	3772796
153544729	153544752	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	0.16873949055701865	[5]	[6,5]	4	hSpCas9	positive selection	3772797
153544653	153544676	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCTGCCCAGCTTCTTGGGGG	S100A4	ENSG00000196154	-0.1588894227114932	[5]	[3,4]	-2	hSpCas9	positive selection	3881399
153544725	153544748	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACAAGTACTCGGGCAAAGAGG	S100A4	ENSG00000196154	-0.8703485217165228	[4]	[1,1]	-8	hSpCas9	positive selection	3881400
153544764	153544787	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCCAGGGCCTTCTCCAGAGGG	S100A4	ENSG00000196154	0.020234065070095036	[6]	[5,4]	0	hSpCas9	positive selection	3881401
153544750	153544773	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.1210516879668176	[4]	[4,4]	2	hSpCas9	positive selection	3881402
153544646	153544669	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.23399014976234916	[5]	[6,5]	6	hSpCas9	positive selection	3881403
153544729	153544752	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGCCCGAGTACTTGTGGAAGG	S100A4	ENSG00000196154	0.1510584109331622	[6]	[6,6]	3	hSpCas9	positive selection	3881404
153543795	153543818	1	+	26780180	A375	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.624931346401244	[]	[]	2	hSpCas9	negative selection	3991429
153543854	153543877	1	-	26780180	A375	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	1.70568828652383	[]	[]	9	hSpCas9	negative selection	3991430
153544725	153544748	1	+	26780180	A375	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.178108509227004	[]	[]	0	hSpCas9	negative selection	3991431
153544689	153544712	1	-	26780180	A375	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.537207817276014	[]	[]	1	hSpCas9	negative selection	3991432
153544734	153544757	1	-	26780180	A375	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	1.55024752808308	[]	[]	8	hSpCas9	negative selection	3991433
153544779	153544802	1	-	26780180	A375	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	1.06191776219165	[]	[]	5	hSpCas9	negative selection	3991434
153543795	153543818	1	+	26780180	HT29	viability (GeCKOv2 library)	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.327123631210205	[]	[]	0	hSpCas9	negative selection	4099395
153543854	153543877	1	-	26780180	HT29	viability (GeCKOv2 library)	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	1.69910544675178	[]	[]	8	hSpCas9	negative selection	4099396
153544725	153544748	1	+	26780180	HT29	viability (GeCKOv2 library)	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	-0.156890078307604	[]	[]	-4	hSpCas9	negative selection	4099397
153544689	153544712	1	-	26780180	HT29	viability (GeCKOv2 library)	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.936730604329327	[]	[]	4	hSpCas9	negative selection	4099398
153544734	153544757	1	-	26780180	HT29	viability (GeCKOv2 library)	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.641178793457972	[]	[]	2	hSpCas9	negative selection	4099399
153544779	153544802	1	-	26780180	HT29	viability (GeCKOv2 library)	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.802219214201238	[]	[]	3	hSpCas9	negative selection	4099400
153543795	153543818	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.41008578171130317	[2]	[1,3]	8	hSpCas9	positive selection	4168108
153543790	153543813	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.04542912744339267	[3]	[1,2]	1	hSpCas9	positive selection	4168109
153543854	153543877	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.2299088836761025	[3]	[1,1]	-5	hSpCas9	positive selection	4168111
153544725	153544748	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.1488972438313602	[2]	[2,1]	4	hSpCas9	positive selection	4168112
153544734	153544757	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.16725023913375361	[4]	[2,2]	-4	hSpCas9	positive selection	4168113
153544779	153544802	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.469308821188266	[5]	[4,5]	8	hSpCas9	positive selection	4168114
153543795	153543818	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.12327943330819294	[4]	[4,2,2,0]	1	hSpCas9	positive selection	4232130
153543790	153543813	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTGTAACGAATTCTTTGAAGG	S100A4	ENSG00000196154	0.541091803175146	[1]	[1,2,1,0]	4	hSpCas9	positive selection	4232131
153543854	153543877	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.19583359292101568	[3]	[0,1,1,0]	-3	hSpCas9	positive selection	4232133
153544725	153544748	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	1.748237283251135	[0]	[3,1,1,0]	9	hSpCas9	positive selection	4232134
153544734	153544757	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.0584358452516589	[2]	[0,0,0,1]	-1	hSpCas9	positive selection	4232135
153544779	153544802	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.9102857123920745	[5]	[5,3,2,5]	6	hSpCas9	positive selection	4232136
153544779	153544802	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.0878140515589923	[3]	[3,2]	1	hSpCas9	positive selection	4296187
153544725	153544748	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5425429108206195	[3]	[4,4]	9	hSpCas9	positive selection	4296188
153543854	153543877	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.06561312885505843	[3]	[2,1]	-1	hSpCas9	positive selection	4296189
153543795	153543818	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.08506066850061883	[3]	[3,2]	1	hSpCas9	positive selection	4360441
153544734	153544757	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.17832467201527546	[3]	[3,1]	-4	hSpCas9	positive selection	4360442
153544689	153544712	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.03972951770319889	[3]	[2,1]	0	hSpCas9	positive selection	4360443
153543857	153543879	1	-	27760321	OCIAML3	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.4296075900237157	[581,506]	[477,694]	5	hSpCas9	negative selection	4436566
153543909	153543931	1	+	27760321	OCIAML3	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.3741363898679734	[682,575]	[544,753]	4	hSpCas9	negative selection	4436567
153544647	153544669	1	+	27760321	OCIAML3	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.6763726777286032	[466,329]	[371,649]	7	hSpCas9	negative selection	4436568
153543857	153543879	1	-	27760321	OCIAML2	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.28964595284893896	[581,506]	[474,618]	4	hSpCas9	negative selection	4520029
153543909	153543931	1	+	27760321	OCIAML2	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.5850782110172157	[682,575]	[745,780]	7	hSpCas9	negative selection	4520030
153544647	153544669	1	+	27760321	OCIAML2	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.40352683105634657	[466,329]	[388,464]	5	hSpCas9	negative selection	4520031
153543857	153543879	1	-	27760321	MV411	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.5375129957472973	[581,506]	[640,338]	4	hSpCas9	negative selection	4603492
153543909	153543931	1	+	27760321	MV411	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.39834218978001745	[682,575]	[644,395]	3	hSpCas9	negative selection	4603493
153544647	153544669	1	+	27760321	MV411	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	-0.08081100658373916	[466,329]	[189,329]	0	hSpCas9	negative selection	4603494
153543857	153543879	1	-	27760321	HL60	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.13764978408942352	[581,506]	[509,464]	1	hSpCas9	negative selection	4686955
153543909	153543931	1	+	27760321	HL60	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	-0.32061295995340944	[682,575]	[301,524]	-4	hSpCas9	negative selection	4686956
153544647	153544669	1	+	27760321	HL60	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.13666517043032334	[466,329]	[270,441]	1	hSpCas9	negative selection	4686957
153543857	153543879	1	-	27760321	HT1080	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.8054348055344092	[506,395]	[342,282]	4	hSpCas9	negative selection	4770418
153543909	153543931	1	+	27760321	HT1080	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.3252262404675781	[575,449]	[193,323]	1	hSpCas9	negative selection	4770419
153544647	153544669	1	+	27760321	HT1080	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	-0.6706631781172425	[329,257]	[106,36]	-3	hSpCas9	negative selection	4770420
153543857	153543879	1	-	27760321	HT29	viability after 7 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.3160199294559279	[506,395]	[677,452,1019]	5	hSpCas9	negative selection	4853881
153543909	153543931	1	+	27760321	HT29	viability after 7 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.12624148298413584	[575,449]	[1014,566,621]	2	hSpCas9	negative selection	4853882
153544647	153544669	1	+	27760321	HT29	viability after 7 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.42941501287621453	[329,257]	[492,449,578]	6	hSpCas9	negative selection	4853883
153543857	153543879	1	-	27760321	HT29	viability after 25 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.30022513951091884	[506,395]	[555,728,623]	3	hSpCas9	negative selection	4937344
153543909	153543931	1	+	27760321	HT29	viability after 25 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.5474455809424834	[575,449]	[915,823,821]	6	hSpCas9	negative selection	4937345
153544647	153544669	1	+	27760321	HT29	viability after 25 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.9232665667515756	[329,257]	[474,618,848]	9	hSpCas9	negative selection	4937346
153543857	153543879	1	-	27760321	HT29	viability after 22 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.4768756753464864	[506,395]	[454,970,760]	5	hSpCas9	negative selection	5020807
153543909	153543931	1	+	27760321	HT29	viability after 22 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	-0.04112425821654908	[575,449]	[631,596,497]	0	hSpCas9	negative selection	5020808
153544647	153544669	1	+	27760321	HT29	viability after 22 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	1.231277627159333	[329,257]	[466,930,1006]	9	hSpCas9	negative selection	5020809
153543857	153543879	1	-	27760321	HT29	viability after 19 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.331207997163148	[506,395]	[602,753,588]	3	hSpCas9	negative selection	5104270
153543909	153543931	1	+	27760321	HT29	viability after 19 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.38317222129024775	[575,449]	[740,929,626]	3	hSpCas9	negative selection	5104271
153544647	153544669	1	+	27760321	HT29	viability after 19 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.9167934641891546	[329,257]	[479,988,426]	8	hSpCas9	negative selection	5104272
153543857	153543879	1	-	27760321	HT29	viability after 16 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.08465573369694257	[506,395]	[522,412,672]	0	hSpCas9	negative selection	5187733
153543909	153543931	1	+	27760321	HT29	viability after 16 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.3603587870535869	[575,449]	[723,629,857]	4	hSpCas9	negative selection	5187734
153544647	153544669	1	+	27760321	HT29	viability after 16 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	1.174659651309872	[329,257]	[372,886,928]	9	hSpCas9	negative selection	5187735
153543857	153543879	1	-	27760321	HT29	viability after 13 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.3645377641619501	[506,395]	[423,760,828]	4	hSpCas9	negative selection	5271196
153543909	153543931	1	+	27760321	HT29	viability after 13 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.24214346646769624	[575,449]	[788,456,855]	3	hSpCas9	negative selection	5271197
153544647	153544669	1	+	27760321	HT29	viability after 13 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.9809528470609384	[329,257]	[591,807,622]	9	hSpCas9	negative selection	5271198
153543857	153543879	1	-	27760321	HT29	viability after 10 days	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.1253190278510018	[506,395]	[588,633,621]	1	hSpCas9	negative selection	5354659
153543909	153543931	1	+	27760321	HT29	viability after 10 days	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.17839114397008637	[575,449]	[835,665,671]	2	hSpCas9	negative selection	5354660
153544647	153544669	1	+	27760321	HT29	viability after 10 days	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.9820285183121905	[329,257]	[678,839,660]	9	hSpCas9	negative selection	5354661
153543857	153543879	1	-	27760321	MOLM13	viability	GACAGCAACAGGGACAACGAGG	S100A4	ENSG00000196154	0.03049010571779781	[581,506]	[305,318]	0	hSpCas9	negative selection	5438122
153543909	153543931	1	+	27760321	MOLM13	viability	TTCATCTGTCCTTTTCTGGAGG	S100A4	ENSG00000196154	0.11797971428127163	[682,575]	[309,446]	0	hSpCas9	negative selection	5438123
153544647	153544669	1	+	27760321	MOLM13	viability	CACTCACCCCCAAGAAGCTGGG	S100A4	ENSG00000196154	0.3149772591500911	[466,329]	[139,392]	2	hSpCas9	negative selection	5438124
153545333	153545356	1	+	27661255	K562	viability	GTGCAGGGCAGAGGCTCATGGGG	S100A4	ENSG00000196154	0.19789184566263185	[763,753]	[707,684]	6	dCas9-KRAB	negative selection	5509116
153545436	153545459	1	+	27661255	K562	viability	GAGCCAGTGCAGATACCCACAGG	S100A4	ENSG00000196154	0.29556261387793303	[969,1058]	[1113,889]	8	dCas9-KRAB	negative selection	5509117
153545100	153545123	1	-	27661255	K562	viability	GGAGTGGATAGACTGAGTGAGGG	S100A4	ENSG00000196154	0.11234364001072075	[555,663]	[537,513]	4	dCas9-KRAB	negative selection	5509118
153545374	153545397	1	-	27661255	K562	viability	GAAAGGCAGAAGGCAACTGTGGG	S100A4	ENSG00000196154	0.10950841850256388	[1578,1294]	[1346,1153]	4	dCas9-KRAB	negative selection	5509119
153545439	153545462	1	-	27661255	K562	viability	GTGCCTGTGGGTATCTGCACTGG	S100A4	ENSG00000196154	-0.060004017754014316	[715,759]	[606,528]	-2	dCas9-KRAB	negative selection	5509120
153544779	153544802	1	-	27260156	BXPC3	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.3701157245064254	[909]	[1136,1135,1207,1474]	7	hSpCas9	negative selection	5568647
153544725	153544748	1	+	27260156	BXPC3	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.4392152157915632	[971]	[1376,1338,1278,1525]	8	hSpCas9	negative selection	5568648
153543854	153543877	1	-	27260156	BXPC3	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.20791997650917543	[624]	[523,558,557,630]	-5	hSpCas9	negative selection	5568649
153543795	153543818	1	+	27260156	BXPC3	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.07415704675299406	[881]	[757,971,1061,1128]	1	hSpCas9	negative selection	5632901
153544734	153544757	1	-	27260156	BXPC3	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.09355617784247144	[603]	[591,537,774,822]	2	hSpCas9	negative selection	5632902
153544689	153544712	1	-	27260156	BXPC3	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.18150150298578815	[491]	[385,452,419,573]	-4	hSpCas9	negative selection	5632903
153544779	153544802	1	-	27260156	A673	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.2782266210685217	[909]	[1291,1176,1342,1494]	6	hSpCas9	negative selection	5689898
153544725	153544748	1	+	27260156	A673	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5231249119462613	[971]	[1728,1730,1631,1614]	9	hSpCas9	negative selection	5689899
153543854	153543877	1	-	27260156	A673	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.05000173562596211	[624]	[842,647,767,862]	1	hSpCas9	negative selection	5689900
153543795	153543818	1	+	27260156	A673	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.003940717498125412	[881]	[1219,903,1020,1126]	0	hSpCas9	negative selection	5754152
153544734	153544757	1	-	27260156	A673	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.1804599682822498	[603]	[729,735,841,977]	4	hSpCas9	negative selection	5754153
153544689	153544712	1	-	27260156	A673	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.28001009997785203	[491]	[418,456,331,745]	-6	hSpCas9	negative selection	5754154
153544779	153544802	1	-	27260156	A375	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.3595616642773135	[909]	[1337,1652,1434,1095]	5	hSpCas9	negative selection	5811149
153544725	153544748	1	+	27260156	A375	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.7380162258978469	[971]	[1732,2092,2046,1738]	9	hSpCas9	negative selection	5811150
153543854	153543877	1	-	27260156	A375	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.6708120562859847	[624]	[483,469,613,286]	-7	hSpCas9	negative selection	5811151
153543795	153543818	1	+	27260156	A375	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.004426684330156583	[881]	[1113,1121,870,1034]	0	hSpCas9	negative selection	5875403
153544734	153544757	1	-	27260156	A375	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.010565170379386701	[603]	[770,747,653,639]	0	hSpCas9	negative selection	5875404
153544689	153544712	1	-	27260156	A375	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.078840299921033	[491]	[488,421,582,649]	-1	hSpCas9	negative selection	5875405
153544779	153544802	1	-	27260156	COLO741	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.24288292822406488	[909]	[1349,1584,1200]	5	hSpCas9	negative selection	5932400
153544725	153544748	1	+	27260156	COLO741	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.49302173009983963	[971]	[1912,1656,1687]	8	hSpCas9	negative selection	5932401
153543854	153543877	1	-	27260156	COLO741	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.39754023272175243	[624]	[780,544,512]	-7	hSpCas9	negative selection	5932402
153543795	153543818	1	+	27260156	COLO741	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.23216348787506835	[881]	[1099,998,800]	-5	hSpCas9	negative selection	5996654
153544734	153544757	1	-	27260156	COLO741	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.4078383496225548	[603]	[1222,939,929]	8	hSpCas9	negative selection	5996655
153544689	153544712	1	-	27260156	COLO741	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.24053249311657046	[491]	[559,457,575]	-5	hSpCas9	negative selection	5996656
153544779	153544802	1	-	27260156	CAL120	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.6036714374235103	[909]	[1548,1657,1924]	8	hSpCas9	negative selection	6053651
153544725	153544748	1	+	27260156	CAL120	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.6570379372960979	[971]	[2289,1716,1773]	8	hSpCas9	negative selection	6053652
153543854	153543877	1	-	27260156	CAL120	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.20599457021587037	[624]	[782,589,665]	-3	hSpCas9	negative selection	6053653
153543795	153543818	1	+	27260156	CAL120	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.0037849742375725137	[881]	[1328,960,1029]	0	hSpCas9	negative selection	6117905
153544734	153544757	1	-	27260156	CAL120	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.25513360632072385	[603]	[790,835,1044]	4	hSpCas9	negative selection	6117906
153544689	153544712	1	-	27260156	CAL120	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.08793249820306201	[491]	[544,534,641]	-1	hSpCas9	negative selection	6117907
153544779	153544802	1	-	27260156	CADOES1	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.44762398803068837	[909]	[1282,1143,1179,1003]	7	hSpCas9	negative selection	6174902
153544725	153544748	1	+	27260156	CADOES1	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.6657640151977215	[971]	[1458,1359,1516,1398]	9	hSpCas9	negative selection	6174903
153543854	153543877	1	-	27260156	CADOES1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.349793106092103	[624]	[469,477,408,467]	-6	hSpCas9	negative selection	6174904
153543795	153543818	1	+	27260156	CADOES1	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.05190789972514398	[881]	[790,767,772,1077]	0	hSpCas9	negative selection	6239156
153544734	153544757	1	-	27260156	CADOES1	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.29008443587390614	[603]	[610,588,819,728]	5	hSpCas9	negative selection	6239157
153544689	153544712	1	-	27260156	CADOES1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.009472175731545816	[491]	[335,424,464,597]	0	hSpCas9	negative selection	6239158
153544779	153544802	1	-	27260156	EWS502	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.49172361281772126	[909]	[1219,1287,1351,1591]	8	hSpCas9	negative selection	6296153
153544725	153544748	1	+	27260156	EWS502	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.7325736983849647	[971]	[1670,1297,1801,2116]	9	hSpCas9	negative selection	6296154
153543854	153543877	1	-	27260156	EWS502	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5945927618500619	[624]	[253,462,519,544]	-7	hSpCas9	negative selection	6296155
153543795	153543818	1	+	27260156	EWS502	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.20789282024327893	[881]	[1077,1143,1155,920]	3	hSpCas9	negative selection	6360407
153544734	153544757	1	-	27260156	EWS502	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.3895492312732913	[603]	[641,707,889,1161]	6	hSpCas9	negative selection	6360408
153544689	153544712	1	-	27260156	EWS502	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.31410999565304987	[491]	[226,372,409,710]	-5	hSpCas9	negative selection	6360409
153544779	153544802	1	-	27260156	EW8	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.23006266930935093	[909]	[1085,735,590,1113]	4	hSpCas9	negative selection	6417404
153544725	153544748	1	+	27260156	EW8	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.6314724175327862	[971]	[1395,1110,1295,1080]	9	hSpCas9	negative selection	6417405
153543854	153543877	1	-	27260156	EW8	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5187897285293486	[624]	[367,360,309,382]	-7	hSpCas9	negative selection	6417406
153543795	153543818	1	+	27260156	EW8	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.008046255772166111	[881]	[859,799,486,748]	0	hSpCas9	negative selection	6481658
153544734	153544757	1	-	27260156	EW8	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.4330974200654116	[603]	[959,532,554,643]	7	hSpCas9	negative selection	6481659
153544689	153544712	1	-	27260156	EW8	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.36703954104385506	[491]	[364,429,182,285]	-6	hSpCas9	negative selection	6481660
153544779	153544802	1	-	27260156	CORL105	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.39935917079627103	[909]	[1596,1262,1533,1255]	7	hSpCas9	negative selection	6538655
153544725	153544748	1	+	27260156	CORL105	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.48375573098584246	[971]	[1801,1369,1535,1658]	8	hSpCas9	negative selection	6538656
153543854	153543877	1	-	27260156	CORL105	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5037077359162254	[624]	[367,503,887,357]	-7	hSpCas9	negative selection	6538657
153543795	153543818	1	+	27260156	CORL105	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.12792053064345343	[881]	[924,780,1368,773]	-2	hSpCas9	negative selection	6602909
153544734	153544757	1	-	27260156	CORL105	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.11166202204457809	[603]	[739,658,798,863]	2	hSpCas9	negative selection	6602910
153544689	153544712	1	-	27260156	CORL105	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.1696599471437757	[491]	[506,551,453,524]	-3	hSpCas9	negative selection	6602911
153544779	153544802	1	-	27260156	HS294T	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.3871920402169612	[909]	[432,360,581,470]	5	hSpCas9	negative selection	6659906
153544725	153544748	1	+	27260156	HS294T	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.45813415132702895	[971]	[569,452,507,531]	6	hSpCas9	negative selection	6659907
153543854	153543877	1	-	27260156	HS294T	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.34876735527038255	[624]	[159,170,220,213]	-5	hSpCas9	negative selection	6659908
153543795	153543818	1	+	27260156	HS294T	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.03205368212011084	[881]	[212,368,270,593]	0	hSpCas9	negative selection	6724160
153544734	153544757	1	-	27260156	HS294T	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.12031302227932811	[603]	[276,368,164,185]	1	hSpCas9	negative selection	6724161
153544689	153544712	1	-	27260156	HS294T	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.0833782922204926	[491]	[173,146,189,213]	-1	hSpCas9	negative selection	6724162
153544779	153544802	1	-	27260156	HCC44	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.19080624835750915	[909]	[974,1313,1361,1036]	3	hSpCas9	negative selection	6781157
153544725	153544748	1	+	27260156	HCC44	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5532811629149268	[971]	[1833,1210,1818,1685]	8	hSpCas9	negative selection	6781158
153543854	153543877	1	-	27260156	HCC44	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.6403642890291757	[624]	[473,347,568,455]	-7	hSpCas9	negative selection	6781159
153543795	153543818	1	+	27260156	HCC44	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.08499563354660022	[881]	[1228,900,1142,1004]	1	hSpCas9	negative selection	6845411
153544734	153544757	1	-	27260156	HCC44	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.25550934488122995	[603]	[1132,765,639,724]	4	hSpCas9	negative selection	6845412
153544689	153544712	1	-	27260156	HCC44	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.3677410151857635	[491]	[505,332,581,349]	-5	hSpCas9	negative selection	6845413
153544779	153544802	1	-	27260156	G402	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.4144649381618214	[909]	[1464,1798,1348,1324]	5	hSpCas9	negative selection	6902408
153544725	153544748	1	+	27260156	G402	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.8082612968955578	[971]	[2415,2490,1887,1600]	8	hSpCas9	negative selection	6902409
153543854	153543877	1	-	27260156	G402	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.4460945991210205	[624]	[523,548,530,623]	-5	hSpCas9	negative selection	6902410
153543795	153543818	1	+	27260156	G402	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.3042722931078382	[881]	[1675,1045,1607,1028]	4	hSpCas9	negative selection	6966662
153544734	153544757	1	-	27260156	G402	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.20560391502400738	[603]	[1082,841,750,757]	2	hSpCas9	negative selection	6966663
153544689	153544712	1	-	27260156	G402	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.18413530059018285	[491]	[649,287,581,591]	-2	hSpCas9	negative selection	6966664
153544779	153544802	1	-	27260156	L33	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.21332569863916218	[909]	[963,427,725,1058]	4	hSpCas9	negative selection	7023659
153544725	153544748	1	+	27260156	L33	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.3988817896685153	[971]	[1418,502,799,1203]	8	hSpCas9	negative selection	7023660
153543854	153543877	1	-	27260156	L33	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.19029467606272327	[624]	[742,297,338,839]	4	hSpCas9	negative selection	7023661
153543795	153543818	1	+	27260156	L33	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.09791192638756308	[881]	[997,372,697,757]	2	hSpCas9	negative selection	7087913
153544734	153544757	1	-	27260156	L33	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.2090010429610234	[603]	[534,174,306,637]	-5	hSpCas9	negative selection	7087914
153544689	153544712	1	-	27260156	L33	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.00621288953615208	[491]	[592,216,273,398]	0	hSpCas9	negative selection	7087915
153544779	153544802	1	-	27260156	K562	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.4024584786154425	[909]	[1012,952,1196,1088]	5	hSpCas9	negative selection	7144910
153544725	153544748	1	+	27260156	K562	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5429097948616539	[971]	[1342,924,1730,1037]	7	hSpCas9	negative selection	7144911
153543854	153543877	1	-	27260156	K562	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5214912750903021	[624]	[443,413,502,209]	-6	hSpCas9	negative selection	7144912
153543795	153543818	1	+	27260156	K562	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.02367600595266217	[881]	[1302,518,608,685]	0	hSpCas9	negative selection	7209164
153544734	153544757	1	-	27260156	K562	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.4510838382345557	[603]	[857,607,764,703]	6	hSpCas9	negative selection	7209165
153544689	153544712	1	-	27260156	K562	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.3611518065035021	[491]	[381,323,438,228]	-4	hSpCas9	negative selection	7209166
153544779	153544802	1	-	27260156	HT29	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.49670842324853537	[909]	[1738,1542,1713,1282]	8	hSpCas9	negative selection	7266161
153544725	153544748	1	+	27260156	HT29	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.7191268016857801	[971]	[2154,2366,1723,1613]	9	hSpCas9	negative selection	7266162
153543854	153543877	1	-	27260156	HT29	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.34070379146067686	[624]	[642,586,642,532]	-6	hSpCas9	negative selection	7266163
153543795	153543818	1	+	27260156	HT29	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.0866147900851375	[881]	[1247,1041,1306,969]	1	hSpCas9	negative selection	7330415
153544734	153544757	1	-	27260156	HT29	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.38054190166132146	[603]	[1120,967,864,884]	7	hSpCas9	negative selection	7330416
153544689	153544712	1	-	27260156	HT29	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.17751031297526004	[491]	[643,585,435,466]	-4	hSpCas9	negative selection	7330417
153544779	153544802	1	-	27260156	MHHES1	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.2871446473508482	[909]	[1335,1320,1397,996]	5	hSpCas9	negative selection	7387412
153544725	153544748	1	+	27260156	MHHES1	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.7061943964034203	[971]	[2345,1766,1681,1451]	9	hSpCas9	negative selection	7387413
153543854	153543877	1	-	27260156	MHHES1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.37521143502530335	[624]	[609,561,565,451]	-6	hSpCas9	negative selection	7387414
153543795	153543818	1	+	27260156	MHHES1	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.10277500850307941	[881]	[934,1270,795,752]	-2	hSpCas9	negative selection	7451666
153544734	153544757	1	-	27260156	MHHES1	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.0788786480066686	[603]	[629,553,942,706]	1	hSpCas9	negative selection	7451667
153544689	153544712	1	-	27260156	MHHES1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.23981735695745537	[491]	[623,626,492,216]	-4	hSpCas9	negative selection	7451668
153544779	153544802	1	-	27260156	MEWO	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.05236016468072335	[909]	[869,841,933]	1	hSpCas9	negative selection	7508663
153544725	153544748	1	+	27260156	MEWO	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5508140656699945	[971]	[1795,920,1370]	9	hSpCas9	negative selection	7508664
153543854	153543877	1	-	27260156	MEWO	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.22881047740776994	[624]	[489,510,493]	-5	hSpCas9	negative selection	7508665
153543795	153543818	1	+	27260156	MEWO	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.17715304941690857	[881]	[1127,829,878]	4	hSpCas9	negative selection	7572917
153544734	153544757	1	-	27260156	MEWO	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.11380917709379157	[603]	[685,547,614]	2	hSpCas9	negative selection	7572918
153544689	153544712	1	-	27260156	MEWO	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.17905584361236648	[491]	[509,336,392]	-4	hSpCas9	negative selection	7572919
153544779	153544802	1	-	27260156	LNCAPCLONEFGC	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.2703157490640117	[909]	[791,1223,974,970]	4	hSpCas9	negative selection	7629914
153544725	153544748	1	+	27260156	LNCAPCLONEFGC	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.7069502636743337	[971]	[1388,1215,2072,1179]	9	hSpCas9	negative selection	7629915
153543854	153543877	1	-	27260156	LNCAPCLONEFGC	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-1.1495285767990124	[624]	[255,217,240,305]	-9	hSpCas9	negative selection	7629916
153543795	153543818	1	+	27260156	LNCAPCLONEFGC	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.05398580440181411	[881]	[930,863,654,836]	0	hSpCas9	negative selection	7694168
153544734	153544757	1	-	27260156	LNCAPCLONEFGC	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.09319349861047516	[603]	[549,510,487,497]	-1	hSpCas9	negative selection	7694169
153544689	153544712	1	-	27260156	LNCAPCLONEFGC	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.28805269343812445	[491]	[367,265,335,491]	-4	hSpCas9	negative selection	7694170
153544779	153544802	1	-	27260156	PANC0327	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.3351981323708507	[909]	[1173,1059,841,1009]	5	hSpCas9	negative selection	7751165
153544725	153544748	1	+	27260156	PANC0327	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.31107842308261424	[971]	[1508,776,887,1183]	4	hSpCas9	negative selection	7751166
153543854	153543877	1	-	27260156	PANC0327	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.2641742591150505	[624]	[345,361,755,388]	-4	hSpCas9	negative selection	7751167
153543795	153543818	1	+	27260156	PANC0327	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.09958196233176653	[881]	[701,1060,893,660]	1	hSpCas9	negative selection	7815419
153544734	153544757	1	-	27260156	PANC0327	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.02118987118676524	[603]	[872,426,561,357]	0	hSpCas9	negative selection	7815420
153544689	153544712	1	-	27260156	PANC0327	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.20720390969227412	[491]	[325,515,578,580]	3	hSpCas9	negative selection	7815421
153544779	153544802	1	-	27260156	NCIH2009	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.4313497077134406	[909]	[1972,1695,1522]	6	hSpCas9	negative selection	7872416
153544725	153544748	1	+	27260156	NCIH2009	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.8446594945488808	[971]	[2983,2001,2441]	9	hSpCas9	negative selection	7872417
153543854	153543877	1	-	27260156	NCIH2009	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.2984527985885902	[624]	[1209,529,490]	-4	hSpCas9	negative selection	7872418
153543795	153543818	1	+	27260156	NCIH2009	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.07374466556731918	[881]	[1622,1021,1312]	1	hSpCas9	negative selection	7936670
153544734	153544757	1	-	27260156	NCIH2009	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.13249458942900355	[603]	[973,689,685]	-2	hSpCas9	negative selection	7936671
153544689	153544712	1	-	27260156	NCIH2009	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.2304183739587297	[491]	[821,697,902]	3	hSpCas9	negative selection	7936672
153544779	153544802	1	-	27260156	NCIH1373	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.8850067637217015	[909]	[2774,1162,2052,456]	8	hSpCas9	negative selection	7993667
153544725	153544748	1	+	27260156	NCIH1373	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	1.0540461847304725	[971]	[2253,2464,2401,489]	9	hSpCas9	negative selection	7993668
153543854	153543877	1	-	27260156	NCIH1373	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.8803133207534097	[624]	[539,158,273,160]	-7	hSpCas9	negative selection	7993669
153543795	153543818	1	+	27260156	NCIH1373	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.15145606411254142	[881]	[1106,1366,923,250]	1	hSpCas9	negative selection	8057921
153544734	153544757	1	-	27260156	NCIH1373	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.40067939120797813	[603]	[623,445,475,138]	-4	hSpCas9	negative selection	8057922
153544689	153544712	1	-	27260156	NCIH1373	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.23769443884753363	[491]	[976,476,756,115]	2	hSpCas9	negative selection	8057923
153544779	153544802	1	-	27260156	PATU8902	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.5384489984875237	[909]	[1492,2126,1600,2242]	5	hSpCas9	negative selection	8114918
153544725	153544748	1	+	27260156	PATU8902	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.8381505872946906	[971]	[1873,2303,2760,2669]	8	hSpCas9	negative selection	8114919
153543854	153543877	1	-	27260156	PATU8902	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-1.026498326010959	[624]	[544,244,444,468]	-7	hSpCas9	negative selection	8114920
153543795	153543818	1	+	27260156	PATU8902	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.1760594661271192	[881]	[1109,1487,735,1099]	-2	hSpCas9	negative selection	8179172
153544734	153544757	1	-	27260156	PATU8902	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.28978112026982566	[603]	[1068,690,486,527]	-3	hSpCas9	negative selection	8179173
153544689	153544712	1	-	27260156	PATU8902	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.6736101779985181	[491]	[301,402,371,684]	-6	hSpCas9	negative selection	8179174
153544779	153544802	1	-	27260156	PANC1	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.2326706393577761	[909]	[743,885,1135,894]	4	hSpCas9	negative selection	8236169
153544725	153544748	1	+	27260156	PANC1	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.6410191894143578	[971]	[1354,1295,1773,839]	9	hSpCas9	negative selection	8236170
153543854	153543877	1	-	27260156	PANC1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.04829520670103865	[624]	[586,553,368,555]	-1	hSpCas9	negative selection	8236171
153543795	153543818	1	+	27260156	PANC1	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.23137933076307216	[881]	[908,1011,953,720]	3	hSpCas9	negative selection	8300423
153544734	153544757	1	-	27260156	PANC1	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.30170482687321315	[603]	[568,816,582,618]	5	hSpCas9	negative selection	8300424
153544689	153544712	1	-	27260156	PANC1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.11861607649688408	[491]	[206,526,345,485]	-2	hSpCas9	negative selection	8300425
153544779	153544802	1	-	27260156	PANC0813	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.3567805685361555	[909]	[1179,1677,1318,1282]	6	hSpCas9	negative selection	8357420
153544725	153544748	1	+	27260156	PANC0813	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.8166903626294828	[971]	[2220,1948,2056,1842]	9	hSpCas9	negative selection	8357421
153543854	153543877	1	-	27260156	PANC0813	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.4267988825577979	[624]	[810,495,366,533]	-6	hSpCas9	negative selection	8357422
153543795	153543818	1	+	27260156	PANC0813	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.03753551927692045	[881]	[1271,1048,987,966]	0	hSpCas9	negative selection	8421674
153544734	153544757	1	-	27260156	PANC0813	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.2762860464074497	[603]	[537,576,599,620]	-4	hSpCas9	negative selection	8421675
153544689	153544712	1	-	27260156	PANC0813	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.21095558653999094	[491]	[625,768,893,397]	3	hSpCas9	negative selection	8421676
153544779	153544802	1	-	27260156	RDES	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.26818313437858243	[909]	[1045,1255,1381,1388]	4	hSpCas9	negative selection	8478671
153544725	153544748	1	+	27260156	RDES	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.8613399872126302	[971]	[1438,1964,2440,2431]	9	hSpCas9	negative selection	8478672
153543854	153543877	1	-	27260156	RDES	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.5578852682212841	[624]	[486,466,464,523]	-7	hSpCas9	negative selection	8478673
153543795	153543818	1	+	27260156	RDES	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.060207710476300025	[881]	[932,961,1079,1294]	1	hSpCas9	negative selection	8542925
153544734	153544757	1	-	27260156	RDES	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.1797569230560115	[603]	[535,792,865,1022]	3	hSpCas9	negative selection	8542926
153544689	153544712	1	-	27260156	RDES	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.3655692383659913	[491]	[331,472,371,609]	-6	hSpCas9	negative selection	8542927
153544779	153544802	1	-	27260156	PC3	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.1654996368997773	[909]	[694,944,1835,947]	3	hSpCas9	negative selection	8599922
153544725	153544748	1	+	27260156	PC3	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.37202993870139944	[971]	[856,1183,1956,1340]	7	hSpCas9	negative selection	8599923
153543854	153543877	1	-	27260156	PC3	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.03996051009988982	[624]	[384,743,799,743]	0	hSpCas9	negative selection	8599924
153543795	153543818	1	+	27260156	PC3	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.048829360133771815	[881]	[661,658,1382,898]	-1	hSpCas9	negative selection	8664176
153544734	153544757	1	-	27260156	PC3	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.13723567013580373	[603]	[436,585,1225,654]	3	hSpCas9	negative selection	8664177
153544689	153544712	1	-	27260156	PC3	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.24644466776426358	[491]	[311,372,721,363]	-5	hSpCas9	negative selection	8664178
153544779	153544802	1	-	27260156	PATU8988T	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.39441098782154616	[909]	[1269,1002,1016,1334]	6	hSpCas9	negative selection	8721173
153544725	153544748	1	+	27260156	PATU8988T	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.4963915697001555	[971]	[931,1094,1896,1347]	8	hSpCas9	negative selection	8721174
153543854	153543877	1	-	27260156	PATU8988T	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.5279306651976421	[624]	[940,819,1008,691]	8	hSpCas9	negative selection	8721175
153543795	153543818	1	+	27260156	PATU8988T	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.18992051790923659	[881]	[833,1052,1194,796]	3	hSpCas9	negative selection	8785427
153544734	153544757	1	-	27260156	PATU8988T	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.10610564366076597	[603]	[877,427,568,618]	1	hSpCas9	negative selection	8785428
153544689	153544712	1	-	27260156	PATU8988T	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.028223815966487376	[491]	[725,372,365,385]	0	hSpCas9	negative selection	8785429
153544779	153544802	1	-	27260156	T47D	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.13897252087858536	[909]	[1131,1109,1207,1224]	3	hSpCas9	negative selection	8842424
153544725	153544748	1	+	27260156	T47D	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.4812535761797281	[971]	[1489,1471,1607,1766]	8	hSpCas9	negative selection	8842425
153543854	153543877	1	-	27260156	T47D	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.610718714748471	[624]	[510,398,470,534]	-8	hSpCas9	negative selection	8842426
153543795	153543818	1	+	27260156	T47D	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.18269500583698972	[881]	[1229,1146,1065,1226]	4	hSpCas9	negative selection	8906678
153544734	153544757	1	-	27260156	T47D	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.08423750914018852	[603]	[770,683,775,757]	1	hSpCas9	negative selection	8906679
153544689	153544712	1	-	27260156	T47D	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.24614860356053095	[491]	[412,498,502,516]	-5	hSpCas9	negative selection	8906680
153544779	153544802	1	-	27260156	SU8686	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.4660590967428754	[909]	[1115,1228,1232,1446]	7	hSpCas9	negative selection	8963675
153544725	153544748	1	+	27260156	SU8686	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.6072120421902489	[971]	[1225,1282,1495,1993]	8	hSpCas9	negative selection	8963676
153543854	153543877	1	-	27260156	SU8686	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.3682057689679256	[624]	[496,419,500,509]	-6	hSpCas9	negative selection	8963677
153543795	153543818	1	+	27260156	SU8686	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.07564468169783523	[881]	[811,860,959,1095]	1	hSpCas9	negative selection	9027929
153544734	153544757	1	-	27260156	SU8686	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.028207741248999052	[603]	[618,537,520,682]	0	hSpCas9	negative selection	9027930
153544689	153544712	1	-	27260156	SU8686	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.11157699529584081	[491]	[416,400,674,666]	1	hSpCas9	negative selection	9027931
153544779	153544802	1	-	27260156	SKES1	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.2386792266394372	[909]	[934,1144,1003,1167]	5	hSpCas9	negative selection	9084926
153544725	153544748	1	+	27260156	SKES1	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5229876657524661	[971]	[1823,1308,1377,1128]	9	hSpCas9	negative selection	9084927
153543854	153543877	1	-	27260156	SKES1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.2632994817665041	[624]	[648,523,530,400]	-5	hSpCas9	negative selection	9084928
153543795	153543818	1	+	27260156	SKES1	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	0.06301300126308584	[881]	[822,1122,998,751]	1	hSpCas9	negative selection	9149180
153544734	153544757	1	-	27260156	SKES1	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.04989974962944166	[603]	[692,532,691,573]	1	hSpCas9	negative selection	9149181
153544689	153544712	1	-	27260156	SKES1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.4561903816932409	[491]	[300,394,394,334]	-7	hSpCas9	negative selection	9149182
153544779	153544802	1	-	27260156	TOV112D	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.25672312806213304	[909]	[1016,1551,811,1080]	5	hSpCas9	negative selection	9206177
153544725	153544748	1	+	27260156	TOV112D	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.5040662122993402	[971]	[1569,1891,1361,852]	8	hSpCas9	negative selection	9206178
153543854	153543877	1	-	27260156	TOV112D	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.15931739631313713	[624]	[526,848,541,395]	-3	hSpCas9	negative selection	9206179
153543795	153543818	1	+	27260156	TOV112D	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.028674972909502494	[881]	[916,968,879,729]	0	hSpCas9	negative selection	9270431
153544734	153544757	1	-	27260156	TOV112D	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.03509439348005067	[603]	[546,1078,586,378]	0	hSpCas9	negative selection	9270432
153544689	153544712	1	-	27260156	TOV112D	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.08450036430540794	[491]	[380,931,329,326]	-2	hSpCas9	negative selection	9270433
153544779	153544802	1	-	27260156	TC71	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.27364861506997007	[909]	[988,1094,1260,1385]	6	hSpCas9	negative selection	9327428
153544725	153544748	1	+	27260156	TC71	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.3907913203348006	[971]	[1311,1220,1460,1474]	8	hSpCas9	negative selection	9327429
153543854	153543877	1	-	27260156	TC71	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.22063270011105257	[624]	[514,536,590,662]	-5	hSpCas9	negative selection	9327430
153543795	153543818	1	+	27260156	TC71	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.03041565883455033	[881]	[796,890,1060,953]	0	hSpCas9	negative selection	9391682
153544734	153544757	1	-	27260156	TC71	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	0.38654337238709385	[603]	[1011,844,654,877]	8	hSpCas9	negative selection	9391683
153544689	153544712	1	-	27260156	TC71	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.2517281238724019	[491]	[431,393,372,583]	-6	hSpCas9	negative selection	9391684
153544779	153544802	1	-	27260156	TC32	viability	TGCTGTCATGGCGTGCCCTCTGG	S100A4	ENSG00000196154	0.06503669288329428	[909]	[896,550,1239,1036]	1	hSpCas9	negative selection	9448679
153544725	153544748	1	+	27260156	TC32	viability	CCTCTTTGCCCGAGTACTTGTGG	S100A4	ENSG00000196154	0.47262701853688993	[971]	[1118,967,1763,1367]	7	hSpCas9	negative selection	9448680
153543854	153543877	1	-	27260156	TC32	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.6822237908796867	[624]	[337,309,443,388]	-8	hSpCas9	negative selection	9448681
153543795	153543818	1	+	27260156	TC32	viability	AAAGAATTCGTTACACATCATGG	S100A4	ENSG00000196154	-0.3965698445179131	[881]	[637,433,737,770]	-6	hSpCas9	negative selection	9512933
153544734	153544757	1	-	27260156	TC32	viability	GTCCACCTTCCACAAGTACTCGG	S100A4	ENSG00000196154	-0.1280281594273094	[603]	[464,319,652,727]	-2	hSpCas9	negative selection	9512934
153544689	153544712	1	-	27260156	TC32	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.5142772674371404	[491]	[260,308,378,349]	-7	hSpCas9	negative selection	9512935
153544773	153544796	1	-	27869803	HPAFII	viability after 27 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.4707045406421626	[281]	[205,204,NaN]	4	hSpCas9	negative selection	9529066
153544773	153544796	1	-	27869803	HPAFII	viability after 15 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.28780760053529864	[281]	[414,341,NaN]	3	hSpCas9	negative selection	9611515
153544773	153544796	1	-	27869803	ASPC1	viability after 36 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.8597454281981378	[444]	[256,328,258]	8	hSpCas9	negative selection	9693964
153544773	153544796	1	-	27869803	PATU8988S	viability after 35 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.3229305075874762	[652]	[100,319,NaN]	-3	hSpCas9	negative selection	9776413
153544773	153544796	1	-	27869803	PATU8988S	viability after 31 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.2721766873893321	[652]	[80,386,NaN]	-3	hSpCas9	negative selection	9858862
153544773	153544796	1	-	27869803	HPAFII	viability after 35 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	1.1214732509094156	[281]	[224,406,NaN]	7	hSpCas9	negative selection	9941311
153544773	153544796	1	-	27869803	HPAFII	viability after 31 days	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.6183778848720802	[281]	[174,316,NaN]	4	hSpCas9	negative selection	10023760
153544758	153544781	1	-	28162770	P31FUJ	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.004236992886470781	[167]	[197]	0	hSpCas9	negative selection	10229318
153543866	153543889	1	-	28162770	P31FUJ	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.41616690875399875	[168]	[264]	4	hSpCas9	negative selection	10229319
153544750	153544773	1	+	28162770	P31FUJ	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.11224777592731172	[358]	[455]	1	hSpCas9	negative selection	10229320
153544773	153544796	1	-	28162770	P31FUJ	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.30315665097452915	[528]	[766]	3	hSpCas9	negative selection	10229321
153544689	153544712	1	-	28162770	P31FUJ	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.8932775439651967	[218]	[477]	8	hSpCas9	negative selection	10229322
153544732	153544755	1	+	28162770	P31FUJ	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.8886613080712884	[147]	[321]	8	hSpCas9	negative selection	10229323
153544674	153544697	1	-	28162770	P31FUJ	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.18281406858270216	[311]	[322]	-2	hSpCas9	negative selection	10229324
153544654	153544677	1	-	28162770	P31FUJ	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.19430812716504028	[237]	[319]	2	hSpCas9	negative selection	10229325
153543854	153543877	1	-	28162770	P31FUJ	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.294958680476948	[165]	[158]	-3	hSpCas9	negative selection	10229326
153543768	153543791	1	-	28162770	P31FUJ	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.0077147648579878	[112]	[266]	9	hSpCas9	negative selection	10229327
153544758	153544781	1	-	28162770	TF1	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10398684
153543866	153543889	1	-	28162770	TF1	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10398685
153544750	153544773	1	+	28162770	TF1	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	NaN	[NaN]	[589]	1	hSpCas9	negative selection	10398686
153544773	153544796	1	-	28162770	TF1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	NaN	[NaN]	[411]	1	hSpCas9	negative selection	10398687
153544689	153544712	1	-	28162770	TF1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10398688
153544732	153544755	1	+	28162770	TF1	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10398689
153544674	153544697	1	-	28162770	TF1	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10398690
153544654	153544677	1	-	28162770	TF1	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10398691
153543854	153543877	1	-	28162770	TF1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10398692
153543768	153543791	1	-	28162770	TF1	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10398693
153544758	153544781	1	-	28162770	SKM1	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.3624228731154219	[54]	[124]	3	hSpCas9	negative selection	10568050
153543866	153543889	1	-	28162770	SKM1	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	1.5894245477044593	[24]	[132]	9	hSpCas9	negative selection	10568051
153544750	153544773	1	+	28162770	SKM1	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.14389044765773018	[106]	[208]	1	hSpCas9	negative selection	10568052
153544773	153544796	1	-	28162770	SKM1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	1.0625210845580588	[142]	[527]	8	hSpCas9	negative selection	10568053
153544689	153544712	1	-	28162770	SKM1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.9238148137264662	[64]	[217]	8	hSpCas9	negative selection	10568054
153544732	153544755	1	+	28162770	SKM1	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	-0.30979553973616336	[60]	[86]	-3	hSpCas9	negative selection	10568055
153544674	153544697	1	-	28162770	SKM1	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.9811409727486842	[48]	[170]	8	hSpCas9	negative selection	10568056
153544654	153544677	1	-	28162770	SKM1	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.6293566200796095	[55]	[63]	-5	hSpCas9	negative selection	10568057
153543854	153543877	1	-	28162770	SKM1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.06864166560513074	[34]	[58]	0	hSpCas9	negative selection	10568058
153543768	153543791	1	-	28162770	SKM1	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10568059
153544758	153544781	1	-	28162770	SKM1	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.3624228731154219	[54]	[124]	3	hSpCas9	negative selection	10737416
153543866	153543889	1	-	28162770	SKM1	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	1.5894245477044593	[24]	[132]	9	hSpCas9	negative selection	10737417
153544750	153544773	1	+	28162770	SKM1	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.14389044765773018	[106]	[208]	1	hSpCas9	negative selection	10737418
153544773	153544796	1	-	28162770	SKM1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	1.0625210845580588	[142]	[527]	8	hSpCas9	negative selection	10737419
153544689	153544712	1	-	28162770	SKM1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.9238148137264662	[64]	[217]	8	hSpCas9	negative selection	10737420
153544732	153544755	1	+	28162770	SKM1	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	-0.30979553973616336	[60]	[86]	-3	hSpCas9	negative selection	10737421
153544674	153544697	1	-	28162770	SKM1	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.9811409727486842	[48]	[170]	8	hSpCas9	negative selection	10737422
153544654	153544677	1	-	28162770	SKM1	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.6293566200796095	[55]	[63]	-5	hSpCas9	negative selection	10737423
153543854	153543877	1	-	28162770	SKM1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.06864166560513074	[34]	[58]	0	hSpCas9	negative selection	10737424
153543768	153543791	1	-	28162770	SKM1	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10737425
153544758	153544781	1	-	28162770	PL21	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.668692623095166	[171]	[118]	6	hSpCas9	negative selection	10906782
153543866	153543889	1	-	28162770	PL21	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.5900861328053335	[144]	[94]	5	hSpCas9	negative selection	10906783
153544750	153544773	1	+	28162770	PL21	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.8940976295680356	[428]	[346]	7	hSpCas9	negative selection	10906784
153544773	153544796	1	-	28162770	PL21	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.056818764144071165	[496]	[224]	0	hSpCas9	negative selection	10906785
153544689	153544712	1	-	28162770	PL21	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.7628721678270108	[217]	[160]	6	hSpCas9	negative selection	10906786
153544732	153544755	1	+	28162770	PL21	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.10157578000573075	[211]	[98]	0	hSpCas9	negative selection	10906787
153544674	153544697	1	-	28162770	PL21	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.6073149959951936	[183]	[121]	5	hSpCas9	negative selection	10906788
153544654	153544677	1	-	28162770	PL21	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.43763892821597644	[189]	[111]	4	hSpCas9	negative selection	10906789
153543854	153543877	1	-	28162770	PL21	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	1.1684307547619819	[91]	[89]	8	hSpCas9	negative selection	10906790
153543768	153543791	1	-	28162770	PL21	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.8028041169439352	[107]	[81]	7	hSpCas9	negative selection	10906791
153544758	153544781	1	-	28162770	P31FUJ	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.004236992886470781	[167]	[197]	0	hSpCas9	negative selection	11076148
153543866	153543889	1	-	28162770	P31FUJ	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.41616690875399875	[168]	[264]	4	hSpCas9	negative selection	11076149
153544750	153544773	1	+	28162770	P31FUJ	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.11224777592731172	[358]	[455]	1	hSpCas9	negative selection	11076150
153544773	153544796	1	-	28162770	P31FUJ	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.30315665097452915	[528]	[766]	3	hSpCas9	negative selection	11076151
153544689	153544712	1	-	28162770	P31FUJ	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.8932775439651967	[218]	[477]	8	hSpCas9	negative selection	11076152
153544732	153544755	1	+	28162770	P31FUJ	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.8886613080712884	[147]	[321]	8	hSpCas9	negative selection	11076153
153544674	153544697	1	-	28162770	P31FUJ	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.18281406858270216	[311]	[322]	-2	hSpCas9	negative selection	11076154
153544654	153544677	1	-	28162770	P31FUJ	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.19430812716504028	[237]	[319]	2	hSpCas9	negative selection	11076155
153543854	153543877	1	-	28162770	P31FUJ	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.294958680476948	[165]	[158]	-3	hSpCas9	negative selection	11076156
153543768	153543791	1	-	28162770	P31FUJ	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.0077147648579878	[112]	[266]	9	hSpCas9	negative selection	11076157
153544758	153544781	1	-	28162770	OCIAML5	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.40549270490364586	[109]	[262]	3	hSpCas9	negative selection	11245514
153543866	153543889	1	-	28162770	OCIAML5	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.7543969990680813	[110]	[337]	6	hSpCas9	negative selection	11245515
153544750	153544773	1	+	28162770	OCIAML5	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.48713951545520096	[165]	[419]	4	hSpCas9	negative selection	11245516
153544773	153544796	1	-	28162770	OCIAML5	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	-0.5527990733878068	[307]	[378]	-4	hSpCas9	negative selection	11245517
153544689	153544712	1	-	28162770	OCIAML5	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.22950728348518923	[201]	[310]	-2	hSpCas9	negative selection	11245518
153544732	153544755	1	+	28162770	OCIAML5	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	1.8313444179452534	[58]	[378]	9	hSpCas9	negative selection	11245519
153544674	153544697	1	-	28162770	OCIAML5	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	-0.621768951442203	[155]	[182]	-4	hSpCas9	negative selection	11245520
153544654	153544677	1	-	28162770	OCIAML5	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.16175106999661232	[87]	[141]	-1	hSpCas9	negative selection	11245521
153543854	153543877	1	-	28162770	OCIAML5	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-1.4444086019507507	[97]	[64]	-7	hSpCas9	negative selection	11245522
153543768	153543791	1	-	28162770	OCIAML5	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.6310163158379457	[43]	[122]	5	hSpCas9	negative selection	11245523
153544758	153544781	1	-	28162770	EOL1	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	-0.21631476426931506	[429]	[194]	-2	hSpCas9	negative selection	11414880
153543866	153543889	1	-	28162770	EOL1	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	1.075555559670217	[144]	[160]	8	hSpCas9	negative selection	11414881
153544750	153544773	1	+	28162770	EOL1	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.511055741149594	[621]	[466]	4	hSpCas9	negative selection	11414882
153544773	153544796	1	-	28162770	EOL1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.23017405412879666	[889]	[549]	2	hSpCas9	negative selection	11414883
153544689	153544712	1	-	28162770	EOL1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.8797598498236967	[457]	[443]	7	hSpCas9	negative selection	11414884
153544732	153544755	1	+	28162770	EOL1	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	-0.3931925263533944	[343]	[137]	-3	hSpCas9	negative selection	11414885
153544674	153544697	1	-	28162770	EOL1	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.09769667388713327	[297]	[167]	0	hSpCas9	negative selection	11414886
153544654	153544677	1	-	28162770	EOL1	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.12054011795800332	[259]	[125]	-1	hSpCas9	negative selection	11414887
153543854	153543877	1	-	28162770	EOL1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.9613063215806524	[154]	[158]	8	hSpCas9	negative selection	11414888
153543768	153543791	1	-	28162770	EOL1	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.8606755884041497	[126]	[242]	9	hSpCas9	negative selection	11414889
153544758	153544781	1	-	28162770	MOLM13	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	-0.24302578025507576	[310]	[189]	-1	hSpCas9	negative selection	11584246
153543866	153543889	1	-	28162770	MOLM13	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	-0.7170283343732062	[265]	[116]	-4	hSpCas9	negative selection	11584247
153544750	153544773	1	+	28162770	MOLM13	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.7019310813181429	[510]	[600]	5	hSpCas9	negative selection	11584248
153544773	153544796	1	-	28162770	MOLM13	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	1.1361209640296632	[661]	[1051]	8	hSpCas9	negative selection	11584249
153544689	153544712	1	-	28162770	MOLM13	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.6136774771053809	[441]	[488]	4	hSpCas9	negative selection	11584250
153544732	153544755	1	+	28162770	MOLM13	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.47890237426699656	[260]	[262]	3	hSpCas9	negative selection	11584251
153544674	153544697	1	-	28162770	MOLM13	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.5602041315282584	[226]	[241]	4	hSpCas9	negative selection	11584252
153544654	153544677	1	-	28162770	MOLM13	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	1.2612033651244863	[235]	[408]	8	hSpCas9	negative selection	11584253
153543854	153543877	1	-	28162770	MOLM13	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.11105567170901495	[250]	[195]	0	hSpCas9	negative selection	11584254
153543768	153543791	1	-	28162770	MOLM13	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.634999367379837	[113]	[127]	5	hSpCas9	negative selection	11584255
153544758	153544781	1	-	28162770	HEL	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.8271634031377846	[263]	[299]	7	hSpCas9	negative selection	11753612
153543866	153543889	1	-	28162770	HEL	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.18021240694019391	[174]	[126]	1	hSpCas9	negative selection	11753613
153544750	153544773	1	+	28162770	HEL	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.8835040739931181	[456]	[539]	7	hSpCas9	negative selection	11753614
153544773	153544796	1	-	28162770	HEL	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.7623977771042603	[635]	[690]	6	hSpCas9	negative selection	11753615
153544689	153544712	1	-	28162770	HEL	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.5427100136690849	[417]	[389]	4	hSpCas9	negative selection	11753616
153544732	153544755	1	+	28162770	HEL	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.10272373733317533	[236]	[162]	0	hSpCas9	negative selection	11753617
153544674	153544697	1	-	28162770	HEL	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.3594912052770542	[229]	[188]	3	hSpCas9	negative selection	11753618
153544654	153544677	1	-	28162770	HEL	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-0.99599492516178	[245]	[78]	-6	hSpCas9	negative selection	11753619
153543854	153543877	1	-	28162770	HEL	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	-0.9422236687207992	[128]	[42]	-5	hSpCas9	negative selection	11753620
153543768	153543791	1	-	28162770	HEL	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.4076353589143551	[132]	[112]	3	hSpCas9	negative selection	11753621
153544758	153544781	1	-	28162770	MV411	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	0.43405884109740134	[209]	[238]	4	hSpCas9	negative selection	11922978
153543866	153543889	1	-	28162770	MV411	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.3385854388409706	[91]	[97]	3	hSpCas9	negative selection	11922979
153544750	153544773	1	+	28162770	MV411	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	-0.28381436319361353	[434]	[300]	-2	hSpCas9	negative selection	11922980
153544773	153544796	1	-	28162770	MV411	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.7186311765463571	[421]	[584]	6	hSpCas9	negative selection	11922981
153544689	153544712	1	-	28162770	MV411	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.37816693443572674	[269]	[174]	-3	hSpCas9	negative selection	11922982
153544732	153544755	1	+	28162770	MV411	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.32106041392595525	[190]	[200]	3	hSpCas9	negative selection	11922983
153544674	153544697	1	-	28162770	MV411	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	1.1873165583452043	[195]	[375]	9	hSpCas9	negative selection	11922984
153544654	153544677	1	-	28162770	MV411	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	-1.296882965441035	[174]	[59]	-7	hSpCas9	negative selection	11922985
153543854	153543877	1	-	28162770	MV411	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.05867590732760741	[105]	[92]	0	hSpCas9	negative selection	11922986
153543768	153543791	1	-	28162770	MV411	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.7213687391151875	[71]	[99]	6	hSpCas9	negative selection	11922987
153544758	153544781	1	-	28162770	MONOMAC1	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	1.180633799754805	[131]	[342]	8	hSpCas9	negative selection	12092344
153543866	153543889	1	-	28162770	MONOMAC1	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	-0.7346936330023531	[89]	[61]	-6	hSpCas9	negative selection	12092345
153544750	153544773	1	+	28162770	MONOMAC1	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	0.29206563825408627	[279]	[392]	3	hSpCas9	negative selection	12092346
153544773	153544796	1	-	28162770	MONOMAC1	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.03956943349659503	[302]	[356]	0	hSpCas9	negative selection	12092347
153544689	153544712	1	-	28162770	MONOMAC1	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	-0.8938922278516068	[200]	[123]	-6	hSpCas9	negative selection	12092348
153544732	153544755	1	+	28162770	MONOMAC1	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	-0.18831962995844487	[164]	[165]	-2	hSpCas9	negative selection	12092349
153544674	153544697	1	-	28162770	MONOMAC1	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.6708596169331011	[119]	[218]	6	hSpCas9	negative selection	12092350
153544654	153544677	1	-	28162770	MONOMAC1	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	0.6428059277469547	[137]	[246]	6	hSpCas9	negative selection	12092351
153543854	153543877	1	-	28162770	MONOMAC1	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	1.9270844647696337	[63]	[278]	9	hSpCas9	negative selection	12092352
153543768	153543791	1	-	28162770	MONOMAC1	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.34893152204573885	[49]	[72]	3	hSpCas9	negative selection	12092353
153544758	153544781	1	-	28162770	OCIAML2	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	-0.3675363322780578	[53]	[231]	-3	hSpCas9	negative selection	12261710
153543866	153543889	1	-	28162770	OCIAML2	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.10724325069267568	[33]	[202]	1	hSpCas9	negative selection	12261711
153544750	153544773	1	+	28162770	OCIAML2	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	-0.44739751900444447	[76]	[312]	-4	hSpCas9	negative selection	12261712
153544773	153544796	1	-	28162770	OCIAML2	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.4060235399358556	[89]	[660]	4	hSpCas9	negative selection	12261713
153544689	153544712	1	-	28162770	OCIAML2	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.6475516011061527	[40]	[355]	6	hSpCas9	negative selection	12261714
153544732	153544755	1	+	28162770	OCIAML2	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.2775630243472992	[31]	[214]	2	hSpCas9	negative selection	12261715
153544674	153544697	1	-	28162770	OCIAML2	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	0.45781691373280475	[30]	[235]	4	hSpCas9	negative selection	12261716
153544654	153544677	1	-	28162770	OCIAML2	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	1.4362607703663575	[19]	[299]	9	hSpCas9	negative selection	12261717
153543854	153543877	1	-	28162770	OCIAML2	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	1.000675893683428	[10]	[121]	8	hSpCas9	negative selection	12261718
153543768	153543791	1	-	28162770	OCIAML2	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	0.32078355294642136	[12]	[89]	3	hSpCas9	negative selection	12261719
153544758	153544781	1	-	28162770	OCIAML3	viability	GGAGAAGGCCCTGGATGTGATGG	S100A4	ENSG00000196154	-0.20794920801708527	[43]	[114]	-2	hSpCas9	negative selection	12431076
153543866	153543889	1	-	28162770	OCIAML3	viability	GAGCAACTTGGACAGCAACAGGG	S100A4	ENSG00000196154	0.23953121353709605	[38]	[138]	2	hSpCas9	negative selection	12431077
153544750	153544773	1	+	28162770	OCIAML3	viability	GGTGGACACCATCACATCCAGGG	S100A4	ENSG00000196154	-0.5214951405397954	[96]	[203]	-4	hSpCas9	negative selection	12431078
153544773	153544796	1	-	28162770	OCIAML3	viability	CATGGCGTGCCCTCTGGAGAAGG	S100A4	ENSG00000196154	0.33546536347564704	[130]	[498]	3	hSpCas9	negative selection	12431079
153544689	153544712	1	-	28162770	OCIAML3	viability	GCTCAACAAGTCAGAACTAAAGG	S100A4	ENSG00000196154	0.02442956494808124	[70]	[217]	0	hSpCas9	negative selection	12431080
153544732	153544755	1	+	28162770	OCIAML3	viability	GCCCGAGTACTTGTGGAAGGTGG	S100A4	ENSG00000196154	0.009691422978578786	[50]	[154]	0	hSpCas9	negative selection	12431081
153544674	153544697	1	-	28162770	OCIAML3	viability	ACTAAAGGAGCTGCTGACCCGGG	S100A4	ENSG00000196154	1.1355784234764454	[48]	[324]	8	hSpCas9	negative selection	12431082
153544654	153544677	1	-	28162770	OCIAML3	viability	GGGAGCTGCCCAGCTTCTTGGGG	S100A4	ENSG00000196154	1.1208351429439027	[45]	[301]	8	hSpCas9	negative selection	12431083
153543854	153543877	1	-	28162770	OCIAML3	viability	CAGCAACAGGGACAACGAGGTGG	S100A4	ENSG00000196154	0.2584351712619791	[35]	[129]	2	hSpCas9	negative selection	12431084
153543768	153543791	1	-	28162770	OCIAML3	viability	GCTTCCCAGATAAGCAGCCCAGG	S100A4	ENSG00000196154	1.2877294780560171	[26]	[198]	9	hSpCas9	negative selection	12431085