Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 22872
• Symbol: SEC31A
• Description: SEC31 homolog A, COPII coat complex component

DataSource: http://genomecrispr.dkfz.de/#!/results/SEC31A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
82864460	82864483	4	+	26472758	Jiyoye	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.9059812384773152	[91]	[129]	6	hSpCas9	negative selection	143860
82857715	82857738	4	-	26472758	Jiyoye	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.335328396201763	[347]	[207]	-2	hSpCas9	negative selection	143861
82853656	82853679	4	+	26472758	Jiyoye	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	1.4809533076454213	[161]	[340]	8	hSpCas9	negative selection	143862
82851547	82851570	4	-	26472758	Jiyoye	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	-0.05695666730114013	[268]	[194]	0	hSpCas9	negative selection	143863
82851440	82851463	4	+	26472758	Jiyoye	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.06428766798286473	[155]	[122]	0	hSpCas9	negative selection	143864
82848871	82848894	4	-	26472758	Jiyoye	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.2347770978001124	[141]	[90]	-2	hSpCas9	negative selection	143865
82848827	82848850	4	+	26472758	Jiyoye	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.2737561777460049	[302]	[188]	-2	hSpCas9	negative selection	143866
82874729	82874752	4	+	26472758	Jiyoye	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	4.2145303035634765	[0]	[13]	9	hSpCas9	negative selection	143867
82867284	82867307	4	-	26472758	Jiyoye	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.7024491096686247	[40]	[18]	-5	hSpCas9	negative selection	143868
82866893	82866916	4	+	26472758	Jiyoye	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	5.451569500864326	[0]	[32]	9	hSpCas9	negative selection	143869
82864460	82864483	4	+	26472758	KBM7	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.6716540635077849	[545,382]	[402,289]	7	hSpCas9	negative selection	334978
82857715	82857738	4	-	26472758	KBM7	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.5687718212958817	[1020,888]	[281,319]	-5	hSpCas9	negative selection	334979
82853656	82853679	4	+	26472758	KBM7	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	-0.08816998518639507	[1379,935]	[567,447]	-1	hSpCas9	negative selection	334980
82851547	82851570	4	-	26472758	KBM7	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.13640692672533172	[677,795]	[463,315]	1	hSpCas9	negative selection	334981
82851440	82851463	4	+	26472758	KBM7	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.44036625022341286	[538,428]	[330,284]	5	hSpCas9	negative selection	334982
82848871	82848894	4	-	26472758	KBM7	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.005370626522275983	[689,311]	[315,146]	0	hSpCas9	negative selection	334983
82848827	82848850	4	+	26472758	KBM7	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.5901651390434011	[888,644]	[409,649]	6	hSpCas9	negative selection	334984
82874729	82874752	4	+	26472758	KBM7	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-1.2326543362017075	[91,79]	[13,19]	-7	hSpCas9	negative selection	334985
82867284	82867307	4	-	26472758	KBM7	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.18005737967547475	[212,243]	[77,111]	-2	hSpCas9	negative selection	334986
82866893	82866916	4	+	26472758	KBM7	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.9752267651226783	[276,151]	[120,257]	9	hSpCas9	negative selection	334987
82864460	82864483	4	+	26472758	Raji	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.9328858041414632	[157]	[69]	8	hSpCas9	negative selection	526096
82857715	82857738	4	-	26472758	Raji	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.21023156664268017	[667]	[133]	-2	hSpCas9	negative selection	526097
82853656	82853679	4	+	26472758	Raji	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.11250856755146699	[561]	[140]	1	hSpCas9	negative selection	526098
82851547	82851570	4	-	26472758	Raji	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.39987754168105744	[306]	[93]	4	hSpCas9	negative selection	526099
82851440	82851463	4	+	26472758	Raji	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.7736461381966041	[183]	[72]	7	hSpCas9	negative selection	526100
82848871	82848894	4	-	26472758	Raji	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	0.2641090390610526	[182]	[50]	2	hSpCas9	negative selection	526101
82848827	82848850	4	+	26472758	Raji	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.795437395925872	[530]	[70]	-6	hSpCas9	negative selection	526102
82874729	82874752	4	+	26472758	Raji	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-1.3076539639052442	[63]	[5]	-7	hSpCas9	negative selection	526103
82867284	82867307	4	-	26472758	Raji	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.3931380177074768	[104]	[31]	4	hSpCas9	negative selection	526104
82866893	82866916	4	+	26472758	Raji	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-3.121435155122281	[149]	[3]	-9	hSpCas9	negative selection	526105
82864460	82864483	4	+	26472758	K562	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.10114502344760162	[475]	[430]	0	hSpCas9	negative selection	717214
82857715	82857738	4	-	26472758	K562	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.42212753530397196	[800]	[905]	3	hSpCas9	negative selection	717215
82853656	82853679	4	+	26472758	K562	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.38109016735550627	[945]	[1039]	3	hSpCas9	negative selection	717216
82851547	82851570	4	-	26472758	K562	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.2822620788111193	[601]	[617]	2	hSpCas9	negative selection	717217
82851440	82851463	4	+	26472758	K562	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.6842168210249109	[492]	[258]	-4	hSpCas9	negative selection	717218
82848871	82848894	4	-	26472758	K562	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.46844400210055714	[276]	[168]	-3	hSpCas9	negative selection	717219
82848827	82848850	4	+	26472758	K562	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.7921034779236336	[770]	[1126]	6	hSpCas9	negative selection	717220
82874729	82874752	4	+	26472758	K562	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.30379727474537854	[118]	[123]	2	hSpCas9	negative selection	717221
82867284	82867307	4	-	26472758	K562	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.0642979591182461	[212]	[187]	0	hSpCas9	negative selection	717222
82866893	82866916	4	+	26472758	K562	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.7490934394299671	[233]	[331]	6	hSpCas9	negative selection	717223
82867284	82867307	4	-	26627737	DLD1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5031537478460824	[571]	[240,342,189]	5	hSpCas9	negative selection	825990
82874662	82874685	4	+	26627737	DLD1	viability	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.17320150187838823	[309]	[85,81,151]	1	hSpCas9	negative selection	825991
82878854	82878877	4	-	26627737	DLD1	viability	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.1415080121397542	[403]	[86,167,93]	-1	hSpCas9	negative selection	825992
82880789	82880812	4	+	26627737	DLD1	viability	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.3381694275429193	[569]	[77,306,57]	-4	hSpCas9	negative selection	825993
82881895	82881918	4	-	26627737	DLD1	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.6550806035281753	[613]	[264,390,260]	6	hSpCas9	negative selection	825994
82891114	82891137	4	-	26627737	DLD1	viability	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.3722667564739005	[773]	[455,245,244]	4	hSpCas9	negative selection	825995
82867284	82867307	4	-	26627737	GBM cells	viability after 5 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.3630035264010276	[505]	[372,324]	5	hSpCas9	negative selection	908305
82874662	82874685	4	+	26627737	GBM cells	viability after 5 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.5873809513607017	[120]	[87,106]	8	hSpCas9	negative selection	908306
82878854	82878877	4	-	26627737	GBM cells	viability after 5 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.3557715498591566	[203]	[145,133]	5	hSpCas9	negative selection	908307
82880789	82880812	4	+	26627737	GBM cells	viability after 5 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.012570656681252568	[365]	[183,211]	0	hSpCas9	negative selection	908308
82881895	82881918	4	-	26627737	GBM cells	viability after 5 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.040881490908398876	[351]	[182,183]	0	hSpCas9	negative selection	908309
82891114	82891137	4	-	26627737	GBM cells	viability after 5 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.051947096929224834	[419]	[258,207]	0	hSpCas9	negative selection	908310
82867284	82867307	4	-	26627737	GBM cells	viability after 13 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5880540361893336	[505]	[431,396]	7	hSpCas9	negative selection	990620
82874662	82874685	4	+	26627737	GBM cells	viability after 13 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.0016747768138416	[120]	[147,117]	9	hSpCas9	negative selection	990621
82878854	82878877	4	-	26627737	GBM cells	viability after 13 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.48969794770265984	[203]	[166,145]	6	hSpCas9	negative selection	990622
82880789	82880812	4	+	26627737	GBM cells	viability after 13 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.49856650370946826	[365]	[155,127]	-5	hSpCas9	negative selection	990623
82881895	82881918	4	-	26627737	GBM cells	viability after 13 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.0394905922426847	[351]	[219,176]	0	hSpCas9	negative selection	990624
82891114	82891137	4	-	26627737	GBM cells	viability after 13 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.1851163582827008	[419]	[284,237]	2	hSpCas9	negative selection	990625
82867284	82867307	4	-	26627737	GBM cells	viability after 21 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.7445059151127718	[505]	[505,418]	7	hSpCas9	negative selection	1072935
82874662	82874685	4	+	26627737	GBM cells	viability after 21 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.9561006250786577	[120]	[114,138]	8	hSpCas9	negative selection	1072936
82878854	82878877	4	-	26627737	GBM cells	viability after 21 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.04582125878206	[203]	[244,213]	9	hSpCas9	negative selection	1072937
82880789	82880812	4	+	26627737	GBM cells	viability after 21 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.4986462709297464	[365]	[146,134]	-4	hSpCas9	negative selection	1072938
82881895	82881918	4	-	26627737	GBM cells	viability after 21 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.0855847355237428	[351]	[239,168]	0	hSpCas9	negative selection	1072939
82891114	82891137	4	-	26627737	GBM cells	viability after 21 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.10058255071473565	[419]	[228,197]	-1	hSpCas9	negative selection	1072940
82867284	82867307	4	-	26627737	RPE1	viability after 9 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.8421379127613693	[1592]	[890,897]	5	hSpCas9	negative selection	1155250
82874662	82874685	4	+	26627737	RPE1	viability after 9 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.886864313263959	[213]	[98,155]	5	hSpCas9	negative selection	1155251
82878854	82878877	4	-	26627737	RPE1	viability after 9 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.2364408772683149	[423]	[348,265]	7	hSpCas9	negative selection	1155252
82880789	82880812	4	+	26627737	RPE1	viability after 9 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.7775298697398927	[883]	[304,692]	5	hSpCas9	negative selection	1155253
82881895	82881918	4	-	26627737	RPE1	viability after 9 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.10504528261722573	[1007]	[231,477]	0	hSpCas9	negative selection	1155254
82891114	82891137	4	-	26627737	RPE1	viability after 9 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.1599125029682964	[1668]	[437,505]	-1	hSpCas9	negative selection	1155255
82867284	82867307	4	-	26627737	RPE1	viability after 12 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	1.4101048542126977	[1592]	[1150,1122]	7	hSpCas9	negative selection	1237565
82874662	82874685	4	+	26627737	RPE1	viability after 12 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.4144549302314986	[213]	[195,107]	7	hSpCas9	negative selection	1237566
82878854	82878877	4	-	26627737	RPE1	viability after 12 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.9013515823772663	[423]	[340,76]	5	hSpCas9	negative selection	1237567
82880789	82880812	4	+	26627737	RPE1	viability after 12 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.7118351972678982	[883]	[303,478]	4	hSpCas9	negative selection	1237568
82881895	82881918	4	-	26627737	RPE1	viability after 12 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.8206465585913709	[1007]	[420,538]	5	hSpCas9	negative selection	1237569
82891114	82891137	4	-	26627737	RPE1	viability after 12 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.13613046019074437	[1668]	[442,370]	-1	hSpCas9	negative selection	1237570
82867284	82867307	4	-	26627737	RPE1	viability after 15 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	1.5496550242045444	[1592]	[1420,1220]	8	hSpCas9	negative selection	1319880
82874662	82874685	4	+	26627737	RPE1	viability after 15 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.3639045390160922	[213]	[250,63]	7	hSpCas9	negative selection	1319881
82878854	82878877	4	-	26627737	RPE1	viability after 15 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.5118908848541306	[423]	[253,90]	3	hSpCas9	negative selection	1319882
82880789	82880812	4	+	26627737	RPE1	viability after 15 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	1.4215371613038092	[883]	[593,742]	7	hSpCas9	negative selection	1319883
82881895	82881918	4	-	26627737	RPE1	viability after 15 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.6393919732890041	[1007]	[350,533]	4	hSpCas9	negative selection	1319884
82891114	82891137	4	-	26627737	RPE1	viability after 15 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.09814769467893802	[1668]	[436,444]	0	hSpCas9	negative selection	1319885
82867284	82867307	4	-	26627737	RPE1	viability after 18 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	1.7883526936538499	[1592]	[1381,1594]	8	hSpCas9	negative selection	1402195
82874662	82874685	4	+	26627737	RPE1	viability after 18 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	2.0078022983412853	[213]	[370,83]	8	hSpCas9	negative selection	1402196
82878854	82878877	4	-	26627737	RPE1	viability after 18 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.1001428670752056	[423]	[355,126]	6	hSpCas9	negative selection	1402197
82880789	82880812	4	+	26627737	RPE1	viability after 18 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.9987078188539014	[883]	[365,594]	6	hSpCas9	negative selection	1402198
82881895	82881918	4	-	26627737	RPE1	viability after 18 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.21109702859789686	[1007]	[267,364]	1	hSpCas9	negative selection	1402199
82891114	82891137	4	-	26627737	RPE1	viability after 18 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.08134004000347739	[1668]	[462,490]	0	hSpCas9	negative selection	1402200
82867284	82867307	4	-	26627737	HeLa	viability after 8 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.00561945797817287	[749]	[434,306,261]	0	hSpCas9	negative selection	1484510
82874662	82874685	4	+	26627737	HeLa	viability after 8 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.9782063409685618	[198]	[206,189,125]	7	hSpCas9	negative selection	1484511
82878854	82878877	4	-	26627737	HeLa	viability after 8 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.015818322719290526	[427]	[211,121,221]	0	hSpCas9	negative selection	1484512
82880789	82880812	4	+	26627737	HeLa	viability after 8 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.3898067169641599	[346]	[214,56,96]	-4	hSpCas9	negative selection	1484513
82881895	82881918	4	-	26627737	HeLa	viability after 8 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	1.3892313905296212	[348]	[141,551,439]	8	hSpCas9	negative selection	1484514
82891114	82891137	4	-	26627737	HeLa	viability after 8 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.6995416577918521	[443]	[265,413,254]	6	hSpCas9	negative selection	1484515
82867284	82867307	4	-	26627737	HeLa	viability after 12 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.19321303561266778	[749]	[496,165,167]	-2	hSpCas9	negative selection	1566825
82874662	82874685	4	+	26627737	HeLa	viability after 12 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.13385042009735015	[198]	[73,82,113]	1	hSpCas9	negative selection	1566826
82878854	82878877	4	-	26627737	HeLa	viability after 12 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.3539086830739585	[427]	[172,212,291]	3	hSpCas9	negative selection	1566827
82880789	82880812	4	+	26627737	HeLa	viability after 12 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.1361084522362866	[346]	[178,119,94]	-1	hSpCas9	negative selection	1566828
82881895	82881918	4	-	26627737	HeLa	viability after 12 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	1.2257506008701404	[348]	[475,223,327]	8	hSpCas9	negative selection	1566829
82891114	82891137	4	-	26627737	HeLa	viability after 12 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.53283510560623	[443]	[276,262,256]	4	hSpCas9	negative selection	1566830
82867284	82867307	4	-	26627737	HeLa	viability after 15 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.463484157399203	[749]	[222,186,256]	-4	hSpCas9	negative selection	1649140
82874662	82874685	4	+	26627737	HeLa	viability after 15 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.00360848139934	[198]	[115,171,202]	7	hSpCas9	negative selection	1649141
82878854	82878877	4	-	26627737	HeLa	viability after 15 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.029790769440391718	[427]	[133,213,163]	0	hSpCas9	negative selection	1649142
82880789	82880812	4	+	26627737	HeLa	viability after 15 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.5046089819004699	[346]	[82,42,178]	-4	hSpCas9	negative selection	1649143
82881895	82881918	4	-	26627737	HeLa	viability after 15 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	1.6758722849184746	[348]	[640,402,303]	9	hSpCas9	negative selection	1649144
82891114	82891137	4	-	26627737	HeLa	viability after 15 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	1.088755895885461	[443]	[377,226,561]	7	hSpCas9	negative selection	1649145
82867284	82867307	4	-	26627737	HeLa	viability after 18 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.45579557550491373	[749]	[150,155,256]	-4	hSpCas9	negative selection	1731455
82874662	82874685	4	+	26627737	HeLa	viability after 18 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.022801469576162	[198]	[79,144,202]	7	hSpCas9	negative selection	1731456
82878854	82878877	4	-	26627737	HeLa	viability after 18 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.013662265346601948	[427]	[88,182,163]	0	hSpCas9	negative selection	1731457
82880789	82880812	4	+	26627737	HeLa	viability after 18 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.5652665479214874	[346]	[44,38,178]	-5	hSpCas9	negative selection	1731458
82881895	82881918	4	-	26627737	HeLa	viability after 18 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	1.713851281961324	[348]	[450,336,303]	9	hSpCas9	negative selection	1731459
82891114	82891137	4	-	26627737	HeLa	viability after 18 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	1.052032020801247	[443]	[237,183,561]	7	hSpCas9	negative selection	1731460
82867284	82867307	4	-	26627737	HCT116	viability after 6 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.4962746554366294	[1087]	[248,236]	2	hSpCas9	negative selection	1813770
82874662	82874685	4	+	26627737	HCT116	viability after 6 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	2.9115290247655072	[97]	[200,68]	9	hSpCas9	negative selection	1813771
82878854	82878877	4	-	26627737	HCT116	viability after 6 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-2.7022400001811273	[629]	[40,0]	-9	hSpCas9	negative selection	1813772
82880789	82880812	4	+	26627737	HCT116	viability after 6 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-1.4832097535850197	[606]	[37,31]	-7	hSpCas9	negative selection	1813773
82881895	82881918	4	-	26627737	HCT116	viability after 6 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	1.429353086719067	[823]	[529,248]	7	hSpCas9	negative selection	1813774
82891114	82891137	4	-	26627737	HCT116	viability after 6 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.6779705458406342	[1573]	[173,143]	-4	hSpCas9	negative selection	1813775
82867284	82867307	4	-	26627737	HCT116	viability after 8 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5512731036918203	[402]	[332,370,272]	5	hSpCas9	negative selection	1896085
82874662	82874685	4	+	26627737	HCT116	viability after 8 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.1596436501025251	[85]	[58,88,167]	8	hSpCas9	negative selection	1896086
82878854	82878877	4	-	26627737	HCT116	viability after 8 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.34598027494994377	[345]	[184,145,119]	-4	hSpCas9	negative selection	1896087
82880789	82880812	4	+	26627737	HCT116	viability after 8 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.30615017415623647	[315]	[147,164,109]	-4	hSpCas9	negative selection	1896088
82881895	82881918	4	-	26627737	HCT116	viability after 8 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.19535486141729586	[341]	[208,204,232]	2	hSpCas9	negative selection	1896089
82891114	82891137	4	-	26627737	HCT116	viability after 8 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.15795209284195888	[362]	[149,181,204]	-2	hSpCas9	negative selection	1896090
82867284	82867307	4	-	26627737	HCT116	viability after 9 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.05714101271410743	[1087]	[338,231]	0	hSpCas9	negative selection	1978400
82874662	82874685	4	+	26627737	HCT116	viability after 9 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	2.1850977305462034	[97]	[56,167]	9	hSpCas9	negative selection	1978401
82878854	82878877	4	-	26627737	HCT116	viability after 9 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.4821380553227284	[629]	[101,134]	-3	hSpCas9	negative selection	1978402
82880789	82880812	4	+	26627737	HCT116	viability after 9 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.9173770130126156	[606]	[614,61]	6	hSpCas9	negative selection	1978403
82881895	82881918	4	-	26627737	HCT116	viability after 9 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.05843071895812041	[823]	[165,278]	0	hSpCas9	negative selection	1978404
82891114	82891137	4	-	26627737	HCT116	viability after 9 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-1.1466062502476095	[1573]	[219,165]	-7	hSpCas9	negative selection	1978405
82867284	82867307	4	-	26627737	HCT116	viability after 12 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.388299115456449	[402]	[306,401,122]	4	hSpCas9	negative selection	2060715
82874662	82874685	4	+	26627737	HCT116	viability after 12 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.362769880835042	[85]	[112,116,118]	9	hSpCas9	negative selection	2060716
82878854	82878877	4	-	26627737	HCT116	viability after 12 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.39551679727506817	[345]	[127,225,372]	4	hSpCas9	negative selection	2060717
82880789	82880812	4	+	26627737	HCT116	viability after 12 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.0064138797843498185	[315]	[143,170,182]	0	hSpCas9	negative selection	2060718
82881895	82881918	4	-	26627737	HCT116	viability after 12 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.5810178648107602	[341]	[170,302,341]	5	hSpCas9	negative selection	2060719
82891114	82891137	4	-	26627737	HCT116	viability after 12 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.5929820717516392	[362]	[337,253,265]	5	hSpCas9	negative selection	2060720
82867284	82867307	4	-	26627737	HCT116	viability after 15 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5688048864620591	[402]	[572,320,165]	5	hSpCas9	negative selection	2143030
82874662	82874685	4	+	26627737	HCT116	viability after 15 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.4784466958636258	[85]	[164,96,153]	9	hSpCas9	negative selection	2143031
82878854	82878877	4	-	26627737	HCT116	viability after 15 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.27814294646446913	[345]	[141,258,308]	2	hSpCas9	negative selection	2143032
82880789	82880812	4	+	26627737	HCT116	viability after 15 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.4517465102659195	[315]	[185,122,95]	-5	hSpCas9	negative selection	2143033
82881895	82881918	4	-	26627737	HCT116	viability after 15 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.3629021709986802	[341]	[315,240,208]	3	hSpCas9	negative selection	2143034
82891114	82891137	4	-	26627737	HCT116	viability after 15 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.3523501497242543	[362]	[363,235,210]	3	hSpCas9	negative selection	2143035
82867284	82867307	4	-	26627737	HCT116	viability after 18 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.3751761315058221	[402]	[263,342,139]	3	hSpCas9	negative selection	2225345
82874662	82874685	4	+	26627737	HCT116	viability after 18 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.8635920556004842	[85]	[98,39,90]	7	hSpCas9	negative selection	2225346
82878854	82878877	4	-	26627737	HCT116	viability after 18 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	-0.26116327941062956	[345]	[101,126,192]	-2	hSpCas9	negative selection	2225347
82880789	82880812	4	+	26627737	HCT116	viability after 18 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.7815842657834983	[315]	[83,78,104]	-6	hSpCas9	negative selection	2225348
82881895	82881918	4	-	26627737	HCT116	viability after 18 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.7373281960369817	[341]	[236,324,260]	6	hSpCas9	negative selection	2225349
82891114	82891137	4	-	26627737	HCT116	viability after 18 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.4269046170974636	[362]	[228,193,289]	3	hSpCas9	negative selection	2225350
82835718	82835741	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGTCTCCTAG	SEC31A	ENSG00000138674	-0.17877550951857135	[78,119]	[17,20]	0	dCas9-VP64	positive selection	2386080
82891367	82891390	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGGTTTCTACGATCGCCGGGG	SEC31A	ENSG00000138674	1.2720292806913802	[97,197]	[90,64]	5	dCas9-VP64	positive selection	2392830
82891416	82891439	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GATGGGGTAGCCAGGACTAGTGG	SEC31A	ENSG00000138674	-0.950742306919035	[514,537]	[52,66]	-5	dCas9-VP64	positive selection	2392831
82891437	82891460	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTAAAGGACTAGTGCAGAGGG	SEC31A	ENSG00000138674	1.5050103543273787	[294,145]	[71,206]	5	dCas9-VP64	positive selection	2392832
82891304	82891327	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGCCTCCCAGGCTACCGCCGG	SEC31A	ENSG00000138674	1.270630306547657	[92,115]	[13,99]	5	dCas9-VP64	positive selection	2408828
82891336	82891359	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTGGTTGGTGGCGCTCTGCGG	SEC31A	ENSG00000138674	-0.13144866172630656	[146,55]	[26,11]	0	dCas9-VP64	positive selection	2408829
82891262	82891285	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGTGCGTCGGGTGGGCGGGG	SEC31A	ENSG00000138674	-1.92889063490892	[5,83]	[0,2]	-9	dCas9-VP64	positive selection	2408830
82869168	82869191	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGTGCGATCTGGG	SEC31A	ENSG00000138674	4.070372888524917	[22,16]	[45,107]	9	dCas9-VP64	positive selection	2443442
82835718	82835741	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGTCTCCTAG	SEC31A	ENSG00000138674	1.3499530185057784	[84,70]	[54,73]	7	dCas9-VP64	positive selection	2481335
82891367	82891390	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGGTTTCTACGATCGCCGGGG	SEC31A	ENSG00000138674	1.307131233424394	[357,271]	[362,153]	7	dCas9-VP64	positive selection	2488085
82891416	82891439	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GATGGGGTAGCCAGGACTAGTGG	SEC31A	ENSG00000138674	-0.2519248995769181	[201,194]	[68,39]	-2	dCas9-VP64	positive selection	2488086
82891437	82891460	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTAAAGGACTAGTGCAGAGGG	SEC31A	ENSG00000138674	-0.18229685101443804	[389,201]	[112,58]	-2	dCas9-VP64	positive selection	2488087
82891304	82891327	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGCCTCCCAGGCTACCGCCGG	SEC31A	ENSG00000138674	-0.2992648318560268	[172,236]	[53,53]	-3	dCas9-VP64	positive selection	2504083
82891336	82891359	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTGGTTGGTGGCGCTCTGCGG	SEC31A	ENSG00000138674	-0.9457374191407727	[107,225]	[17,36]	-8	dCas9-VP64	positive selection	2504084
82891262	82891285	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGTGCGTCGGGTGGGCGGGG	SEC31A	ENSG00000138674	-0.6034304110918649	[84,25]	[11,10]	-6	dCas9-VP64	positive selection	2504085
82869168	82869191	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGTGCGATCTGGG	SEC31A	ENSG00000138674	1.6841538162097147	[121,126]	[189,75]	8	dCas9-VP64	positive selection	2538697
82891116	82891139	4	+	27260157	DLD1	viability	TGCGTTAGTGCAGCGCTCGTCGG	SEC31A	ENSG00000138674	-1.3153933714628	[]	[]	-7	hSpCas9	negative selection	2574607
82872006	82872029	4	+	27260157	DLD1	viability	CACTGGTAACCGGTCATCCTCGG	SEC31A	ENSG00000138674	0.446511871123965	[]	[]	7	hSpCas9	negative selection	2580712
82866823	82866846	4	+	27260157	DLD1	viability	AACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.110144072292837	[]	[]	3	hSpCas9	negative selection	2582115
82867266	82867289	4	-	27260157	DLD1	viability	AGTGGTGCTTCGATATTCAGTGG	SEC31A	ENSG00000138674	-0.703894173324059	[]	[]	-5	hSpCas9	negative selection	2583739
82872037	82872060	4	+	27260157	DLD1	viability	ACCATCTGAGTAGCAACATCAGG	SEC31A	ENSG00000138674	0.160556754253038	[]	[]	3	hSpCas9	negative selection	2585048
82875803	82875826	4	-	27260157	DLD1	viability	CAGACTAATCTGGTAGCTTCTGG	SEC31A	ENSG00000138674	-0.060096019962609	[]	[]	0	hSpCas9	negative selection	2606260
82864460	82864483	4	+	27260157	DLD1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.584524730408758	[]	[]	-5	hSpCas9	negative selection	2606402
82862544	82862567	4	-	27260157	DLD1	viability	TTGGCCTTGAACAAAGTGGATGG	SEC31A	ENSG00000138674	0.854510452330474	[]	[]	9	hSpCas9	negative selection	2606554
82864454	82864477	4	-	27260157	DLD1	viability	CCGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.327889105082511	[]	[]	4	hSpCas9	negative selection	2609145
82871996	82872019	4	+	27260157	DLD1	viability	ACATCTGGATCACTGGTAACCGG	SEC31A	ENSG00000138674	1.08970349402006	[]	[]	9	hSpCas9	negative selection	2613781
82881895	82881918	4	-	27260157	DLD1	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.509210439528017	[]	[]	-4	hSpCas9	negative selection	2616121
82891108	82891131	4	-	27260157	DLD1	viability	CGCTGCACTAACGCAGGATCCGG	SEC31A	ENSG00000138674	0.155092308612685	[]	[]	3	hSpCas9	negative selection	2619637
82872015	82872038	4	-	27260157	DLD1	viability	TCCTTGCCTCCGAGGATGACCGG	SEC31A	ENSG00000138674	-1.02301503827188	[]	[]	-7	hSpCas9	negative selection	2620849
82864502	82864525	4	-	27260157	DLD1	viability	GCACCATGTGTTCATTAGTCAGG	SEC31A	ENSG00000138674	0.879421158405482	[]	[]	9	hSpCas9	negative selection	2641513
82878762	82878785	4	+	27260157	DLD1	viability	GGCCAGTATGCTTGTCATTCTGG	SEC31A	ENSG00000138674	-0.119772854059762	[]	[]	-1	hSpCas9	negative selection	2641629
82874668	82874691	4	+	27260157	DLD1	viability	AGTGGCCCGGCCACTGGGACTGG	SEC31A	ENSG00000138674	0.46378128934185	[]	[]	8	hSpCas9	negative selection	2642709
82871981	82872004	4	+	27260157	DLD1	viability	CAAATCGAAGATCCCACATCTGG	SEC31A	ENSG00000138674	0.186568442712042	[]	[]	3	hSpCas9	negative selection	2643584
82891098	82891121	4	-	27260157	DLD1	viability	ACGCAGGATCCGGCTGCCGAAGG	SEC31A	ENSG00000138674	0.828339209890997	[]	[]	9	hSpCas9	negative selection	2643859
82878907	82878930	4	-	27260157	DLD1	viability	GGTACCACAAGTTGATTTGGGGG	SEC31A	ENSG00000138674	-0.436189951923313	[]	[]	-4	hSpCas9	negative selection	2645150
82878764	82878787	4	-	27260157	DLD1	viability	GCCCAGAATGACAAGCATACTGG	SEC31A	ENSG00000138674	1.07234850133102	[]	[]	9	hSpCas9	negative selection	2649475
82891116	82891139	4	+	27260157	HT1080	viability	TGCGTTAGTGCAGCGCTCGTCGG	SEC31A	ENSG00000138674	-1.8128409901478	[]	[]	-9	hSpCas9	negative selection	2650737
82872006	82872029	4	+	27260157	HT1080	viability	CACTGGTAACCGGTCATCCTCGG	SEC31A	ENSG00000138674	-0.487591162670236	[]	[]	-7	hSpCas9	negative selection	2656842
82866823	82866846	4	+	27260157	HT1080	viability	AACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	-0.473259598522181	[]	[]	-7	hSpCas9	negative selection	2658245
82867266	82867289	4	-	27260157	HT1080	viability	AGTGGTGCTTCGATATTCAGTGG	SEC31A	ENSG00000138674	-0.123094168190354	[]	[]	0	hSpCas9	negative selection	2659869
82872037	82872060	4	+	27260157	HT1080	viability	ACCATCTGAGTAGCAACATCAGG	SEC31A	ENSG00000138674	0.493115895826026	[]	[]	4	hSpCas9	negative selection	2661178
82875803	82875826	4	-	27260157	HT1080	viability	CAGACTAATCTGGTAGCTTCTGG	SEC31A	ENSG00000138674	0.215845087423235	[]	[]	2	hSpCas9	negative selection	2682390
82864460	82864483	4	+	27260157	HT1080	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.205580723484751	[]	[]	0	hSpCas9	negative selection	2682532
82862544	82862567	4	-	27260157	HT1080	viability	TTGGCCTTGAACAAAGTGGATGG	SEC31A	ENSG00000138674	0.314076907997386	[]	[]	3	hSpCas9	negative selection	2682684
82864454	82864477	4	-	27260157	HT1080	viability	CCGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.0548745440472382	[]	[]	0	hSpCas9	negative selection	2685275
82871996	82872019	4	+	27260157	HT1080	viability	ACATCTGGATCACTGGTAACCGG	SEC31A	ENSG00000138674	-0.305128145982514	[]	[]	-7	hSpCas9	negative selection	2689911
82881895	82881918	4	-	27260157	HT1080	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.116313165310001	[]	[]	1	hSpCas9	negative selection	2692251
82891108	82891131	4	-	27260157	HT1080	viability	CGCTGCACTAACGCAGGATCCGG	SEC31A	ENSG00000138674	-1.68183213581569	[]	[]	-9	hSpCas9	negative selection	2695767
82872015	82872038	4	-	27260157	HT1080	viability	TCCTTGCCTCCGAGGATGACCGG	SEC31A	ENSG00000138674	-0.843716981727277	[]	[]	-8	hSpCas9	negative selection	2696979
82864502	82864525	4	-	27260157	HT1080	viability	GCACCATGTGTTCATTAGTCAGG	SEC31A	ENSG00000138674	0.279218251438203	[]	[]	2	hSpCas9	negative selection	2717643
82878762	82878785	4	+	27260157	HT1080	viability	GGCCAGTATGCTTGTCATTCTGG	SEC31A	ENSG00000138674	0.930989684801276	[]	[]	7	hSpCas9	negative selection	2717759
82874668	82874691	4	+	27260157	HT1080	viability	AGTGGCCCGGCCACTGGGACTGG	SEC31A	ENSG00000138674	0.457777908236583	[]	[]	4	hSpCas9	negative selection	2718839
82871981	82872004	4	+	27260157	HT1080	viability	CAAATCGAAGATCCCACATCTGG	SEC31A	ENSG00000138674	0.27267711077268	[]	[]	2	hSpCas9	negative selection	2719714
82891098	82891121	4	-	27260157	HT1080	viability	ACGCAGGATCCGGCTGCCGAAGG	SEC31A	ENSG00000138674	0.647578079280285	[]	[]	5	hSpCas9	negative selection	2719989
82878907	82878930	4	-	27260157	HT1080	viability	GGTACCACAAGTTGATTTGGGGG	SEC31A	ENSG00000138674	-0.59755702129115	[]	[]	-7	hSpCas9	negative selection	2721280
82878764	82878787	4	-	27260157	HT1080	viability	GCCCAGAATGACAAGCATACTGG	SEC31A	ENSG00000138674	-0.277587145601083	[]	[]	-4	hSpCas9	negative selection	2725605
82891116	82891139	4	+	27260157	MKN45	viability	TGCGTTAGTGCAGCGCTCGTCGG	SEC31A	ENSG00000138674	-0.255086932404495	[]	[]	-1	hSpCas9	negative selection	2726867
82872006	82872029	4	+	27260157	MKN45	viability	CACTGGTAACCGGTCATCCTCGG	SEC31A	ENSG00000138674	0.508249777611382	[]	[]	6	hSpCas9	negative selection	2732972
82866823	82866846	4	+	27260157	MKN45	viability	AACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.132298053596163	[]	[]	4	hSpCas9	negative selection	2734375
82867266	82867289	4	-	27260157	MKN45	viability	AGTGGTGCTTCGATATTCAGTGG	SEC31A	ENSG00000138674	0.164366618179756	[]	[]	5	hSpCas9	negative selection	2735999
82872037	82872060	4	+	27260157	MKN45	viability	ACCATCTGAGTAGCAACATCAGG	SEC31A	ENSG00000138674	0.335402071955666	[]	[]	6	hSpCas9	negative selection	2737308
82875803	82875826	4	-	27260157	MKN45	viability	CAGACTAATCTGGTAGCTTCTGG	SEC31A	ENSG00000138674	0.0910723327060177	[]	[]	0	hSpCas9	negative selection	2758520
82864460	82864483	4	+	27260157	MKN45	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.240408517239891	[]	[]	-1	hSpCas9	negative selection	2758662
82862544	82862567	4	-	27260157	MKN45	viability	TTGGCCTTGAACAAAGTGGATGG	SEC31A	ENSG00000138674	-0.00537005382569445	[]	[]	0	hSpCas9	negative selection	2758814
82864454	82864477	4	-	27260157	MKN45	viability	CCGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.387915057896078	[]	[]	6	hSpCas9	negative selection	2761405
82871996	82872019	4	+	27260157	MKN45	viability	ACATCTGGATCACTGGTAACCGG	SEC31A	ENSG00000138674	0.880776675731795	[]	[]	8	hSpCas9	negative selection	2766041
82881895	82881918	4	-	27260157	MKN45	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.0824828339004395	[]	[]	0	hSpCas9	negative selection	2768381
82891108	82891131	4	-	27260157	MKN45	viability	CGCTGCACTAACGCAGGATCCGG	SEC31A	ENSG00000138674	-0.589235132291937	[]	[]	-6	hSpCas9	negative selection	2771897
82872015	82872038	4	-	27260157	MKN45	viability	TCCTTGCCTCCGAGGATGACCGG	SEC31A	ENSG00000138674	-0.667681698665583	[]	[]	-7	hSpCas9	negative selection	2773109
82864502	82864525	4	-	27260157	MKN45	viability	GCACCATGTGTTCATTAGTCAGG	SEC31A	ENSG00000138674	0.779408896398619	[]	[]	7	hSpCas9	negative selection	2793773
82878762	82878785	4	+	27260157	MKN45	viability	GGCCAGTATGCTTGTCATTCTGG	SEC31A	ENSG00000138674	-0.225016759748321	[]	[]	-1	hSpCas9	negative selection	2793889
82874668	82874691	4	+	27260157	MKN45	viability	AGTGGCCCGGCCACTGGGACTGG	SEC31A	ENSG00000138674	-0.334638726987058	[]	[]	-1	hSpCas9	negative selection	2794969
82871981	82872004	4	+	27260157	MKN45	viability	CAAATCGAAGATCCCACATCTGG	SEC31A	ENSG00000138674	0.879358117175318	[]	[]	8	hSpCas9	negative selection	2795844
82891098	82891121	4	-	27260157	MKN45	viability	ACGCAGGATCCGGCTGCCGAAGG	SEC31A	ENSG00000138674	1.07999817521469	[]	[]	8	hSpCas9	negative selection	2796119
82878907	82878930	4	-	27260157	MKN45	viability	GGTACCACAAGTTGATTTGGGGG	SEC31A	ENSG00000138674	-1.05260837870362	[]	[]	-8	hSpCas9	negative selection	2797410
82878764	82878787	4	-	27260157	MKN45	viability	GCCCAGAATGACAAGCATACTGG	SEC31A	ENSG00000138674	0.314796774178143	[]	[]	5	hSpCas9	negative selection	2801735
82891116	82891139	4	+	27260157	RKO	viability	TGCGTTAGTGCAGCGCTCGTCGG	SEC31A	ENSG00000138674	-0.287827257786337	[]	[]	-6	hSpCas9	negative selection	2802997
82872006	82872029	4	+	27260157	RKO	viability	CACTGGTAACCGGTCATCCTCGG	SEC31A	ENSG00000138674	-0.0889225345932688	[]	[]	0	hSpCas9	negative selection	2809102
82866823	82866846	4	+	27260157	RKO	viability	AACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.728037886164459	[]	[]	8	hSpCas9	negative selection	2810505
82867266	82867289	4	-	27260157	RKO	viability	AGTGGTGCTTCGATATTCAGTGG	SEC31A	ENSG00000138674	1.10691606184322	[]	[]	9	hSpCas9	negative selection	2812129
82872037	82872060	4	+	27260157	RKO	viability	ACCATCTGAGTAGCAACATCAGG	SEC31A	ENSG00000138674	0.587147005667363	[]	[]	3	hSpCas9	negative selection	2813438
82875803	82875826	4	-	27260157	RKO	viability	CAGACTAATCTGGTAGCTTCTGG	SEC31A	ENSG00000138674	0.323546748350675	[]	[]	1	hSpCas9	negative selection	2834650
82864460	82864483	4	+	27260157	RKO	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.061382531542789	[]	[]	0	hSpCas9	negative selection	2834792
82862544	82862567	4	-	27260157	RKO	viability	TTGGCCTTGAACAAAGTGGATGG	SEC31A	ENSG00000138674	0.846190915620595	[]	[]	8	hSpCas9	negative selection	2834944
82864454	82864477	4	-	27260157	RKO	viability	CCGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.520366484412518	[]	[]	2	hSpCas9	negative selection	2837535
82871996	82872019	4	+	27260157	RKO	viability	ACATCTGGATCACTGGTAACCGG	SEC31A	ENSG00000138674	1.32023649971585	[]	[]	9	hSpCas9	negative selection	2842171
82881895	82881918	4	-	27260157	RKO	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.382337380031041	[]	[]	2	hSpCas9	negative selection	2844511
82891108	82891131	4	-	27260157	RKO	viability	CGCTGCACTAACGCAGGATCCGG	SEC31A	ENSG00000138674	-0.307700313095734	[]	[]	-6	hSpCas9	negative selection	2848027
82872015	82872038	4	-	27260157	RKO	viability	TCCTTGCCTCCGAGGATGACCGG	SEC31A	ENSG00000138674	-1.02687684320432	[]	[]	-8	hSpCas9	negative selection	2849239
82864502	82864525	4	-	27260157	RKO	viability	GCACCATGTGTTCATTAGTCAGG	SEC31A	ENSG00000138674	-0.31321330425022	[]	[]	-6	hSpCas9	negative selection	2869903
82878762	82878785	4	+	27260157	RKO	viability	GGCCAGTATGCTTGTCATTCTGG	SEC31A	ENSG00000138674	-0.604700697822218	[]	[]	-7	hSpCas9	negative selection	2870019
82874668	82874691	4	+	27260157	RKO	viability	AGTGGCCCGGCCACTGGGACTGG	SEC31A	ENSG00000138674	0.47831294164314	[]	[]	2	hSpCas9	negative selection	2871099
82871981	82872004	4	+	27260157	RKO	viability	CAAATCGAAGATCCCACATCTGG	SEC31A	ENSG00000138674	0.46257564947194	[]	[]	2	hSpCas9	negative selection	2871974
82891098	82891121	4	-	27260157	RKO	viability	ACGCAGGATCCGGCTGCCGAAGG	SEC31A	ENSG00000138674	1.33909063484184	[]	[]	9	hSpCas9	negative selection	2872249
82878907	82878930	4	-	27260157	RKO	viability	GGTACCACAAGTTGATTTGGGGG	SEC31A	ENSG00000138674	-0.314893841802778	[]	[]	-6	hSpCas9	negative selection	2873540
82878764	82878787	4	-	27260157	RKO	viability	GCCCAGAATGACAAGCATACTGG	SEC31A	ENSG00000138674	0.902684605289525	[]	[]	8	hSpCas9	negative selection	2877865
82891116	82891139	4	+	27260157	SF268	viability	TGCGTTAGTGCAGCGCTCGTCGG	SEC31A	ENSG00000138674	-0.793537907059261	[]	[]	-6	hSpCas9	negative selection	2879127
82872006	82872029	4	+	27260157	SF268	viability	CACTGGTAACCGGTCATCCTCGG	SEC31A	ENSG00000138674	-0.700033511890821	[]	[]	-5	hSpCas9	negative selection	2885232
82866823	82866846	4	+	27260157	SF268	viability	AACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	-0.772714174278116	[]	[]	-6	hSpCas9	negative selection	2886635
82867266	82867289	4	-	27260157	SF268	viability	AGTGGTGCTTCGATATTCAGTGG	SEC31A	ENSG00000138674	-0.569660677814486	[]	[]	-4	hSpCas9	negative selection	2888259
82872037	82872060	4	+	27260157	SF268	viability	ACCATCTGAGTAGCAACATCAGG	SEC31A	ENSG00000138674	0.357678112337918	[]	[]	4	hSpCas9	negative selection	2889568
82875803	82875826	4	-	27260157	SF268	viability	CAGACTAATCTGGTAGCTTCTGG	SEC31A	ENSG00000138674	-0.282717486244724	[]	[]	-2	hSpCas9	negative selection	2910780
82864460	82864483	4	+	27260157	SF268	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.468356773401266	[]	[]	-4	hSpCas9	negative selection	2910922
82862544	82862567	4	-	27260157	SF268	viability	TTGGCCTTGAACAAAGTGGATGG	SEC31A	ENSG00000138674	-0.0144435291946877	[]	[]	0	hSpCas9	negative selection	2911074
82864454	82864477	4	-	27260157	SF268	viability	CCGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.245768932852734	[]	[]	-2	hSpCas9	negative selection	2913665
82871996	82872019	4	+	27260157	SF268	viability	ACATCTGGATCACTGGTAACCGG	SEC31A	ENSG00000138674	-1.02867798658904	[]	[]	-7	hSpCas9	negative selection	2918301
82881895	82881918	4	-	27260157	SF268	viability	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.0249261852045414	[]	[]	0	hSpCas9	negative selection	2920641
82891108	82891131	4	-	27260157	SF268	viability	CGCTGCACTAACGCAGGATCCGG	SEC31A	ENSG00000138674	-0.758169119391103	[]	[]	-6	hSpCas9	negative selection	2924157
82872015	82872038	4	-	27260157	SF268	viability	TCCTTGCCTCCGAGGATGACCGG	SEC31A	ENSG00000138674	-1.39743897204144	[]	[]	-8	hSpCas9	negative selection	2925369
82864502	82864525	4	-	27260157	SF268	viability	GCACCATGTGTTCATTAGTCAGG	SEC31A	ENSG00000138674	-0.920239446262683	[]	[]	-6	hSpCas9	negative selection	2946033
82878762	82878785	4	+	27260157	SF268	viability	GGCCAGTATGCTTGTCATTCTGG	SEC31A	ENSG00000138674	-0.392927068620852	[]	[]	-3	hSpCas9	negative selection	2946149
82874668	82874691	4	+	27260157	SF268	viability	AGTGGCCCGGCCACTGGGACTGG	SEC31A	ENSG00000138674	-0.714570846112612	[]	[]	-5	hSpCas9	negative selection	2947229
82871981	82872004	4	+	27260157	SF268	viability	CAAATCGAAGATCCCACATCTGG	SEC31A	ENSG00000138674	-0.855841068547426	[]	[]	-6	hSpCas9	negative selection	2948104
82891098	82891121	4	-	27260157	SF268	viability	ACGCAGGATCCGGCTGCCGAAGG	SEC31A	ENSG00000138674	0.691934698160832	[]	[]	8	hSpCas9	negative selection	2948379
82878907	82878930	4	-	27260157	SF268	viability	GGTACCACAAGTTGATTTGGGGG	SEC31A	ENSG00000138674	-0.930609120852798	[]	[]	-6	hSpCas9	negative selection	2949670
82878764	82878787	4	-	27260157	SF268	viability	GCCCAGAATGACAAGCATACTGG	SEC31A	ENSG00000138674	-1.35637676620628	[]	[]	-7	hSpCas9	negative selection	2953995
82867284	82867307	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.06145421685695862	[4,4]	[4,2]	-1	hSpCas9	positive selection	3019265
82861640	82861663	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	-0.17376630296866166	[3,3]	[2,2]	-2	hSpCas9	positive selection	3019266
82880856	82880879	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	0.2801132679458048	[3,4]	[3,4]	6	hSpCas9	positive selection	3019267
82874678	82874701	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	-0.21845055566558796	[3,3]	[1,3]	-3	hSpCas9	positive selection	3019268
82867284	82867307	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.3413320131266349	[4,4]	[2,1]	-5	hSpCas9	positive selection	3087123
82861640	82861663	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	0.2923760967484411	[3,3]	[2,3]	5	hSpCas9	positive selection	3087124
82880856	82880879	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	0.04559241471029679	[3,3]	[2,2]	0	hSpCas9	positive selection	3087125
82874678	82874701	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	-0.2677149834164196	[3,3]	[2,1]	-4	hSpCas9	positive selection	3087126
82867284	82867307		-	24336571	A375	resistance to PLX after 7 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.26454720689039146	[16,20]	[22,22]	7	hSpCas9	positive selection	3143211
82870368	82870391		+	24336571	A375	resistance to PLX after 7 days	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.14420372440228402	[93,84]	[99,95]	4	hSpCas9	positive selection	3143212
82870368	82870391		-	24336571	A375	resistance to PLX after 7 days	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.10557759746076689	[76,79]	[86,80]	3	hSpCas9	positive selection	3143213
82870317	82870340		+	24336571	A375	resistance to PLX after 7 days	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	-0.139007143847659	[49,47]	[44,43]	-4	hSpCas9	positive selection	3143214
82867222	82867245		-	24336571	A375	resistance to PLX after 7 days	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.08722147585199291	[120,109]	[115,127]	3	hSpCas9	positive selection	3143215
82867284	82867307		-	24336571	A375	resistance to PLX after 14 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.882563147036513	[19,20]	[15,19]	7	hSpCas9	positive selection	3201004
82870368	82870391		+	24336571	A375	resistance to PLX after 14 days	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	3.0366010806841452	[95,96]	[356,385]	9	hSpCas9	positive selection	3201005
82870368	82870391		-	24336571	A375	resistance to PLX after 14 days	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.4111173077205712	[70,90]	[49,50]	4	hSpCas9	positive selection	3201006
82870317	82870340		+	24336571	A375	resistance to PLX after 14 days	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	-0.5833285248960807	[42,40]	[12,12]	-7	hSpCas9	positive selection	3201007
82867222	82867245		-	24336571	A375	resistance to PLX after 14 days	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.22207737761878832	[125,119]	[74,57]	2	hSpCas9	positive selection	3201008
82867284	82867307		-	24336571	A375	viability after 7 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-1.5675610329889973	[60]	[16,20]	-9	hSpCas9	negative selection	3258797
82870368	82870391		+	24336571	A375	viability after 7 days	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.3894860230573518	[71]	[93,84]	6	hSpCas9	negative selection	3258798
82870368	82870391		-	24336571	A375	viability after 7 days	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.25839986599554754	[68]	[76,79]	4	hSpCas9	negative selection	3258799
82870317	82870340		+	24336571	A375	viability after 7 days	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	0.41657679156099126	[38]	[49,47]	6	hSpCas9	negative selection	3258800
82867222	82867245		-	24336571	A375	viability after 7 days	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.47229523628189707	[86]	[120,109]	7	hSpCas9	negative selection	3258801
82867284	82867307		-	24336571	A375	viability after 14 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-1.4579704878134303	[60]	[19,20]	-9	hSpCas9	negative selection	3316590
82870368	82870391		+	24336571	A375	viability after 14 days	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.5188510731043952	[71]	[95,96]	6	hSpCas9	negative selection	3316591
82870368	82870391		-	24336571	A375	viability after 14 days	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.31478072598938533	[68]	[70,90]	4	hSpCas9	negative selection	3316592
82870317	82870340		+	24336571	A375	viability after 14 days	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	0.2173739477871428	[38]	[42,40]	3	hSpCas9	negative selection	3316593
82867222	82867245		-	24336571	A375	viability after 14 days	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5786837166236976	[86]	[125,119]	7	hSpCas9	negative selection	3316594
82870368	82870391	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3391656
82870368	82870391	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.43616074605349014	[206,206]	[0,0]	-3	hSpCas9	positive selection	3391657
82866920	82866943	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.976293465313867	[300,300]	[0,0]	-6	hSpCas9	positive selection	3391658
82867284	82867307	4	-	26780180	HT29	viability (Avana library 4 designs)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.943563609605145	[]	[]	3	hSpCas9	negative selection	3457711
82861639	82861662	4	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	0.065062532252476	[]	[]	0	hSpCas9	negative selection	3457712
82880855	82880878	4	+	26780180	HT29	viability (Avana library 4 designs)	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	1.12799246848843	[]	[]	4	hSpCas9	negative selection	3457713
82874678	82874701	4	-	26780180	HT29	viability (Avana library 4 designs)	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	1.61134660433564	[]	[]	6	hSpCas9	negative selection	3457714
82861639	82861662	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	2.15334302839975	[]	[]	3	hSpCas9	negative selection	3556794
82874678	82874701	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	1.03217219434723	[]	[]	1	hSpCas9	negative selection	3556795
82880855	82880878	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	-18.1820381675682	[]	[]	-9	hSpCas9	negative selection	3556796
82867284	82867307	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-5.66790439285789	[]	[]	-6	hSpCas9	negative selection	3556797
82874729	82874752	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	1.06966074558481	[]	[]	1	hSpCas9	negative selection	3556798
82866806	82866829	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGAAAAAGAAGCACCAACAGG	SEC31A	ENSG00000138674	-4.36202195770528	[]	[]	-5	hSpCas9	negative selection	3556799
82861639	82861662	4	+	26780180	A375	viability (Avana lentiGuide)	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	-4.76461000232819	[]	[]	-7	hSpCas9	negative selection	3665453
82874678	82874701	4	-	26780180	A375	viability (Avana lentiGuide)	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	2.31197832478672	[]	[]	2	hSpCas9	negative selection	3665454
82880855	82880878	4	+	26780180	A375	viability (Avana lentiGuide)	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	-3.45504241179179	[]	[]	-6	hSpCas9	negative selection	3665455
82867284	82867307	4	-	26780180	A375	viability (Avana lentiGuide)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-5.36827588698507	[]	[]	-8	hSpCas9	negative selection	3665456
82874729	82874752	4	+	26780180	A375	viability (Avana lentiGuide)	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.570948658212863	[]	[]	0	hSpCas9	negative selection	3665457
82866806	82866829	4	+	26780180	A375	viability (Avana lentiGuide)	ACTGAAAAAGAAGCACCAACAGG	SEC31A	ENSG00000138674	-6.08964854860918	[]	[]	-9	hSpCas9	negative selection	3665458
82861639	82861662	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	0.04734246315674133	[5]	[5,4]	1	hSpCas9	positive selection	3774060
82874678	82874701	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	-0.10043294189476344	[4]	[5,2]	-2	hSpCas9	positive selection	3774061
82880855	82880878	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	-1.01925733163332	[9]	[4,3]	-9	hSpCas9	positive selection	3774062
82867284	82867307	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.28676129647176296	[5]	[4,3]	-4	hSpCas9	positive selection	3774063
82874729	82874752	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.005739203835712331	[5]	[5,5]	0	hSpCas9	positive selection	3774064
82866806	82866829	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGAAAAAGAAGCACCAACAGG	SEC31A	ENSG00000138674	-0.8577617506906295	[4]	[3,0]	-8	hSpCas9	positive selection	3774065
82861639	82861662	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCTGCTCTTCAGCAGCAGGG	SEC31A	ENSG00000138674	0.33946050853472487	[5]	[6,6]	8	hSpCas9	positive selection	3882667
82874678	82874701	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGCATCAGCCAGTCCCAGTGG	SEC31A	ENSG00000138674	-0.3609650124768714	[5]	[2,4]	-5	hSpCas9	positive selection	3882668
82880855	82880878	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCTAATTCAAATATCTCAAGGG	SEC31A	ENSG00000138674	0.1679351496097728	[5]	[5,4]	4	hSpCas9	positive selection	3882669
82867284	82867307	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.3007646241325687	[5]	[6,5]	8	hSpCas9	positive selection	3882670
82874729	82874752	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.07281846310137656	[5]	[4,5]	1	hSpCas9	positive selection	3882671
82866806	82866829	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGAAAAAGAAGCACCAACAGG	SEC31A	ENSG00000138674	0.30139626408131265	[5]	[5,5]	8	hSpCas9	positive selection	3882672
82866920	82866943	4	-	26780180	A375	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	1.08006189653	[]	[]	5	hSpCas9	negative selection	3992705
82867275	82867298	4	+	26780180	A375	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	1.66732641073241	[]	[]	9	hSpCas9	negative selection	3992706
82870368	82870391	4	+	26780180	A375	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	1.03125806575276	[]	[]	5	hSpCas9	negative selection	3992707
82870368	82870391	4	-	26780180	A375	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	1.11136507407844	[]	[]	5	hSpCas9	negative selection	3992708
82866838	82866861	4	-	26780180	A375	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.580787718019759	[]	[]	1	hSpCas9	negative selection	3992709
82867222	82867245	4	-	26780180	A375	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.538050846221977	[]	[]	1	hSpCas9	negative selection	3992710
82866920	82866943	4	-	26780180	HT29	viability (GeCKOv2 library)	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	1.85107363398387	[]	[]	8	hSpCas9	negative selection	4100671
82867275	82867298	4	+	26780180	HT29	viability (GeCKOv2 library)	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	1.17046174395607	[]	[]	5	hSpCas9	negative selection	4100672
82870368	82870391	4	+	26780180	HT29	viability (GeCKOv2 library)	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	1.68785729732847	[]	[]	8	hSpCas9	negative selection	4100673
82870368	82870391	4	-	26780180	HT29	viability (GeCKOv2 library)	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	1.81791059691323	[]	[]	8	hSpCas9	negative selection	4100674
82866838	82866861	4	-	26780180	HT29	viability (GeCKOv2 library)	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.305131000200547	[]	[]	0	hSpCas9	negative selection	4100675
82867222	82867245	4	-	26780180	HT29	viability (GeCKOv2 library)	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.119796684514061	[]	[]	0	hSpCas9	negative selection	4100676
82867284	82867307	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.19473639804804388	[4]	[3,4]	5	hSpCas9	positive selection	4169018
82870368	82870391	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.4985178068340542	[6]	[4,8]	9	hSpCas9	positive selection	4169019
82870368	82870391	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.2806098090672019	[6]	[4,5]	7	hSpCas9	positive selection	4169020
82870317	82870340	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	0.14281386424557502	[5]	[4,3]	3	hSpCas9	positive selection	4169021
82867222	82867245	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.4162251665099209	[6]	[6,6]	8	hSpCas9	positive selection	4169022
82867284	82867307	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.7971477070560701	[6]	[5,4,5,3]	5	hSpCas9	positive selection	4233040
82870368	82870391	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.8463921320533512	[6]	[5,6,4,4]	5	hSpCas9	positive selection	4233041
82870368	82870391	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.36763911075362177	[5]	[5,4,5,0]	2	hSpCas9	positive selection	4233042
82870317	82870340	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCCATACCTCTCCTGTGTTTGG	SEC31A	ENSG00000138674	1.1547211988020691	[4]	[4,5,3,4]	8	hSpCas9	positive selection	4233043
82867222	82867245	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	1.106777788924548	[5]	[6,4,4,5]	8	hSpCas9	positive selection	4233044
82867222	82867245	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.35740827452564944	[4]	[4,4]	7	hSpCas9	positive selection	4296871
82866838	82866861	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.17883236439787825	[2]	[3,0]	3	hSpCas9	positive selection	4296872
82867275	82867298	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.1495112073230191	[2]	[2,0]	-3	hSpCas9	positive selection	4296873
82870368	82870391	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.5442811636791004	[2]	[2,3]	9	hSpCas9	positive selection	4361125
82870368	82870391	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.25213384471004074	[3]	[2,1]	-5	hSpCas9	positive selection	4361126
82866920	82866943	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.10296840352849274	[4]	[3,2]	-2	hSpCas9	positive selection	4361127
82864454	82864476	4	-	27760321	OCIAML3	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.2602703065589491	[739,617]	[487,822]	3	hSpCas9	negative selection	4437607
82866824	82866846	4	+	27760321	OCIAML3	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.5826513191090332	[613,459]	[495,789]	7	hSpCas9	negative selection	4437608
82866888	82866910	4	+	27760321	OCIAML3	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.32309334183747823	[395,331]	[352,356]	4	hSpCas9	negative selection	4437609
82872010	82872032	4	+	27760321	OCIAML3	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.22206748802036594	[386,401]	[247,288]	-2	hSpCas9	negative selection	4437610
82875740	82875762	4	-	27760321	OCIAML3	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.23524022809378659	[381,311]	[250,404]	2	hSpCas9	negative selection	4437611
82864454	82864476	4	-	27760321	OCIAML2	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.3511403513238881	[739,617]	[386,483]	-4	hSpCas9	negative selection	4521070
82866824	82866846	4	+	27760321	OCIAML2	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.516274980370341	[613,459]	[587,652]	7	hSpCas9	negative selection	4521071
82866888	82866910	4	+	27760321	OCIAML2	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.16359423777645232	[395,331]	[293,373]	2	hSpCas9	negative selection	4521072
82872010	82872032	4	+	27760321	OCIAML2	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	0.16183993214979803	[386,401]	[290,447]	2	hSpCas9	negative selection	4521073
82875740	82875762	4	-	27760321	OCIAML2	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	-0.3068845253908118	[381,311]	[214,239]	-4	hSpCas9	negative selection	4521074
82864454	82864476	4	-	27760321	MV411	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.11634690231315581	[739,617]	[384,631]	0	hSpCas9	negative selection	4604533
82866824	82866846	4	+	27760321	MV411	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	1.4957897325653389	[613,459]	[1350,449]	9	hSpCas9	negative selection	4604534
82866888	82866910	4	+	27760321	MV411	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	-0.15798263810486468	[395,331]	[24,498]	-1	hSpCas9	negative selection	4604535
82872010	82872032	4	+	27760321	MV411	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.359618124231607	[386,401]	[55,425]	-3	hSpCas9	negative selection	4604536
82875740	82875762	4	-	27760321	MV411	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	-2.9160136077627725	[381,311]	[14,52]	-9	hSpCas9	negative selection	4604537
82864454	82864476	4	-	27760321	HL60	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.08929236957470577	[739,617]	[377,668]	-1	hSpCas9	negative selection	4687996
82866824	82866846	4	+	27760321	HL60	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	-0.14222429486439342	[613,459]	[347,442]	-2	hSpCas9	negative selection	4687997
82866888	82866910	4	+	27760321	HL60	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	-0.437473042831085	[395,331]	[241,193]	-5	hSpCas9	negative selection	4687998
82872010	82872032	4	+	27760321	HL60	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.6436934166069938	[386,401]	[182,232]	-6	hSpCas9	negative selection	4687999
82875740	82875762	4	-	27760321	HL60	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	-0.897600593884844	[381,311]	[180,119]	-7	hSpCas9	negative selection	4688000
82864454	82864476	4	-	27760321	HT1080	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	1.186447739284985	[617,481]	[469,529]	6	hSpCas9	negative selection	4771459
82866824	82866846	4	+	27760321	HT1080	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	1.7103070490243735	[459,358]	[529,537]	8	hSpCas9	negative selection	4771460
82866888	82866910	4	+	27760321	HT1080	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.7506555232179495	[331,258]	[93,311]	4	hSpCas9	negative selection	4771461
82872010	82872032	4	+	27760321	HT1080	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	0.2951402221912166	[401,313]	[174,174]	1	hSpCas9	negative selection	4771462
82875740	82875762	4	-	27760321	HT1080	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.5184441480894918	[311,243]	[45,281]	2	hSpCas9	negative selection	4771463
82864454	82864476	4	-	27760321	HT29	viability after 7 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.07412007446865676	[617,481]	[731,838,661]	1	hSpCas9	negative selection	4854922
82866824	82866846	4	+	27760321	HT29	viability after 7 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.6733814835777904	[459,358]	[964,805,766]	8	hSpCas9	negative selection	4854923
82866888	82866910	4	+	27760321	HT29	viability after 7 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.18020837615822483	[331,258]	[474,514,310]	2	hSpCas9	negative selection	4854924
82872010	82872032	4	+	27760321	HT29	viability after 7 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.01101848475259335	[401,313]	[561,341,479]	0	hSpCas9	negative selection	4854925
82875740	82875762	4	-	27760321	HT29	viability after 7 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	-0.0380083723394018	[311,243]	[446,131,474]	0	hSpCas9	negative selection	4854926
82864454	82864476	4	-	27760321	HT29	viability after 25 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.3141387376182646	[617,481]	[524,942,903]	3	hSpCas9	negative selection	4938385
82866824	82866846	4	+	27760321	HT29	viability after 25 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	1.16927260229618	[459,358]	[805,1100,1288]	9	hSpCas9	negative selection	4938386
82866888	82866910	4	+	27760321	HT29	viability after 25 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.5429770636486593	[331,258]	[506,486,478]	6	hSpCas9	negative selection	4938387
82872010	82872032	4	+	27760321	HT29	viability after 25 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.2938864047956242	[401,313]	[446,217,327]	-3	hSpCas9	negative selection	4938388
82875740	82875762	4	-	27760321	HT29	viability after 25 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.4937637310630678	[311,243]	[385,334,644]	5	hSpCas9	negative selection	4938389
82864454	82864476	4	-	27760321	HT29	viability after 22 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.09471262019713933	[617,481]	[517,754,768]	0	hSpCas9	negative selection	5021848
82866824	82866846	4	+	27760321	HT29	viability after 22 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.9517508561846832	[459,358]	[802,925,1021]	9	hSpCas9	negative selection	5021849
82866888	82866910	4	+	27760321	HT29	viability after 22 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.7026243234457235	[331,258]	[470,654,543]	7	hSpCas9	negative selection	5021850
82872010	82872032	4	+	27760321	HT29	viability after 22 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	0.05741730645861205	[401,313]	[580,379,325]	0	hSpCas9	negative selection	5021851
82875740	82875762	4	-	27760321	HT29	viability after 22 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.48849158784770996	[311,243]	[433,497,420]	5	hSpCas9	negative selection	5021852
82864454	82864476	4	-	27760321	HT29	viability after 19 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.2450121511305111	[617,481]	[537,827,237]	-2	hSpCas9	negative selection	5105311
82866824	82866846	4	+	27760321	HT29	viability after 19 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	1.3262399803234428	[459,358]	[1114,877,1509]	9	hSpCas9	negative selection	5105312
82866888	82866910	4	+	27760321	HT29	viability after 19 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.17346304245280836	[331,258]	[540,214,402]	1	hSpCas9	negative selection	5105313
82872010	82872032	4	+	27760321	HT29	viability after 19 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.28592664818275665	[401,313]	[397,177,433]	-3	hSpCas9	negative selection	5105314
82875740	82875762	4	-	27760321	HT29	viability after 19 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.8888715130311151	[311,243]	[414,747,584]	8	hSpCas9	negative selection	5105315
82864454	82864476	4	-	27760321	HT29	viability after 16 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.3752372069180834	[617,481]	[767,618,1008]	4	hSpCas9	negative selection	5188774
82866824	82866846	4	+	27760321	HT29	viability after 16 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.6997295051760324	[459,358]	[818,641,780]	7	hSpCas9	negative selection	5188775
82866888	82866910	4	+	27760321	HT29	viability after 16 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.27448535973040034	[331,258]	[469,483,249]	3	hSpCas9	negative selection	5188776
82872010	82872032	4	+	27760321	HT29	viability after 16 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.26313598325200577	[401,313]	[321,300,377]	-3	hSpCas9	negative selection	5188777
82875740	82875762	4	-	27760321	HT29	viability after 16 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.5943370172405273	[311,243]	[517,523,369]	7	hSpCas9	negative selection	5188778
82864454	82864476	4	-	27760321	HT29	viability after 13 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.008061430686582827	[617,481]	[543,501,864]	0	hSpCas9	negative selection	5272237
82866824	82866846	4	+	27760321	HT29	viability after 13 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.6757696088489543	[459,358]	[654,900,722]	8	hSpCas9	negative selection	5272238
82866888	82866910	4	+	27760321	HT29	viability after 13 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.5038041023111687	[331,258]	[357,623,476]	6	hSpCas9	negative selection	5272239
82872010	82872032	4	+	27760321	HT29	viability after 13 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.11232371900383302	[401,313]	[393,227,521]	-1	hSpCas9	negative selection	5272240
82875740	82875762	4	-	27760321	HT29	viability after 13 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.5526966572094791	[311,243]	[690,445,292]	7	hSpCas9	negative selection	5272241
82864454	82864476	4	-	27760321	HT29	viability after 10 days	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	0.07958808254873984	[617,481]	[591,1030,565]	1	hSpCas9	negative selection	5355700
82866824	82866846	4	+	27760321	HT29	viability after 10 days	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	0.358998296529908	[459,358]	[712,607,644]	5	hSpCas9	negative selection	5355701
82866888	82866910	4	+	27760321	HT29	viability after 10 days	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	0.046213241992677706	[331,258]	[401,395,345]	0	hSpCas9	negative selection	5355702
82872010	82872032	4	+	27760321	HT29	viability after 10 days	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-0.31952653850369733	[401,313]	[483,250,336]	-4	hSpCas9	negative selection	5355703
82875740	82875762	4	-	27760321	HT29	viability after 10 days	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	0.3432427242704834	[311,243]	[472,383,461]	4	hSpCas9	negative selection	5355704
82864454	82864476	4	-	27760321	MOLM13	viability	CGATCAGACCAACTTCAGCAGG	SEC31A	ENSG00000138674	-0.05602214222723112	[739,617]	[467,280]	0	hSpCas9	negative selection	5439163
82866824	82866846	4	+	27760321	MOLM13	viability	ACAGGCCTTCGAATCCACTTGG	SEC31A	ENSG00000138674	-1.405450157430026	[613,459]	[107,117]	-7	hSpCas9	negative selection	5439164
82866888	82866910	4	+	27760321	MOLM13	viability	GCTGTGGAATTTGTAACGGAGG	SEC31A	ENSG00000138674	-0.8535832324105868	[395,331]	[96,126]	-5	hSpCas9	negative selection	5439165
82872010	82872032	4	+	27760321	MOLM13	viability	GGTAACCGGTCATCCTCGGAGG	SEC31A	ENSG00000138674	-1.4114222370481477	[386,401]	[82,84]	-7	hSpCas9	negative selection	5439166
82875740	82875762	4	-	27760321	MOLM13	viability	TTGCAACCCCAATGACACCAGG	SEC31A	ENSG00000138674	-0.7553870359350544	[381,311]	[62,159]	-5	hSpCas9	negative selection	5439167
82890929	82890952	4	+	27661255	K562	viability	GGGCCCGAAACCAAGACTAGGGG	SEC31A	ENSG00000138674	0.09408882338437485	[1071,1089]	[996,856]	3	dCas9-KRAB	negative selection	5509901
82891145	82891168	4	-	27661255	K562	viability	GGAGGGGCGGCGGCGAATGCTGG	SEC31A	ENSG00000138674	0.16675813040356519	[678,713]	[664,588]	6	dCas9-KRAB	negative selection	5509902
82867222	82867245	4	-	27260156	BXPC3	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.3505772626877701	[1106]	[1411,1405,1557,1536]	7	hSpCas9	negative selection	5569331
82866838	82866861	4	-	27260156	BXPC3	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.5151563405708017	[223]	[370,300,305,358]	9	hSpCas9	negative selection	5569332
82867275	82867298	4	+	27260156	BXPC3	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.31955997280117343	[365]	[332,242,342,306]	-6	hSpCas9	negative selection	5569333
82870368	82870391	4	+	27260156	BXPC3	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.18999543071704877	[360]	[309,294,321,407]	-4	hSpCas9	negative selection	5633585
82870368	82870391	4	-	27260156	BXPC3	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.05619628361314816	[654]	[591,607,813,624]	-1	hSpCas9	negative selection	5633586
82866920	82866943	4	-	27260156	BXPC3	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-3.3841934172551547e-05	[1367]	[1219,1313,1464,1786]	0	hSpCas9	negative selection	5633587
82867222	82867245	4	-	27260156	A673	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.3646085287744385	[1106]	[1927,1647,1596,1695]	8	hSpCas9	negative selection	5690582
82866838	82866861	4	-	27260156	A673	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.5131071879222716	[223]	[359,379,403,387]	9	hSpCas9	negative selection	5690583
82867275	82867298	4	+	27260156	A673	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.1494896643310436	[365]	[420,330,340,501]	-4	hSpCas9	negative selection	5690584
82870368	82870391	4	+	27260156	A673	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.005596298038728353	[360]	[409,432,365,533]	0	hSpCas9	negative selection	5754836
82870368	82870391	4	-	27260156	A673	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.010075097149216006	[654]	[997,642,737,771]	0	hSpCas9	negative selection	5754837
82866920	82866943	4	-	27260156	A673	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.1366423073398484	[1367]	[1800,1768,1851,1796]	3	hSpCas9	negative selection	5754838
82867222	82867245	4	-	27260156	A375	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.7777200150226304	[1106]	[2343,2832,1941,1867]	9	hSpCas9	negative selection	5811833
82866838	82866861	4	-	27260156	A375	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.4733121015754336	[223]	[332,485,310,340]	7	hSpCas9	negative selection	5811834
82867275	82867298	4	+	27260156	A375	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.6783403339236096	[365]	[162,266,316,313]	-7	hSpCas9	negative selection	5811835
82870368	82870391	4	+	27260156	A375	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.11952591133444945	[360]	[473,398,570,386]	1	hSpCas9	negative selection	5876087
82870368	82870391	4	-	27260156	A375	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.0136265134490699	[654]	[824,805,705,704]	0	hSpCas9	negative selection	5876088
82866920	82866943	4	-	27260156	A375	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.09780018387918088	[1367]	[1557,2101,1430,1785]	1	hSpCas9	negative selection	5876089
82867222	82867245	4	-	27260156	COLO741	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5056831819784711	[1106]	[1956,2275,1798]	8	hSpCas9	negative selection	5933084
82866838	82866861	4	-	27260156	COLO741	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.07486753382677891	[223]	[259,404,239]	1	hSpCas9	negative selection	5933085
82867275	82867298	4	+	27260156	COLO741	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.20956708325932083	[365]	[460,434,326]	-4	hSpCas9	negative selection	5933086
82870368	82870391	4	+	27260156	COLO741	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.17631242772232703	[360]	[446,499,602]	4	hSpCas9	negative selection	5997338
82870368	82870391	4	-	27260156	COLO741	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.5218183196566436	[654]	[680,651,433]	-8	hSpCas9	negative selection	5997339
82866920	82866943	4	-	27260156	COLO741	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.07442764575325422	[1367]	[2083,1858,1611]	1	hSpCas9	negative selection	5997340
82867222	82867245	4	-	27260156	CAL120	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.493265209720277	[1106]	[2362,1345,2166]	7	hSpCas9	negative selection	6054335
82866838	82866861	4	-	27260156	CAL120	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.057384653500785365	[223]	[267,349,186]	-1	hSpCas9	negative selection	6054336
82867275	82867298	4	+	27260156	CAL120	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.34008758798905614	[365]	[573,206,330]	-5	hSpCas9	negative selection	6054337
82870368	82870391	4	+	27260156	CAL120	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.5053818650728312	[360]	[825,751,367]	7	hSpCas9	negative selection	6118589
82870368	82870391	4	-	27260156	CAL120	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.15857209000619787	[654]	[1011,804,926]	2	hSpCas9	negative selection	6118590
82866920	82866943	4	-	27260156	CAL120	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.5174816692779765	[1367]	[2564,2177,2582]	7	hSpCas9	negative selection	6118591
82867222	82867245	4	-	27260156	CADOES1	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.6644886373579975	[1106]	[1601,1651,1759,1508]	9	hSpCas9	negative selection	6175586
82866838	82866861	4	-	27260156	CADOES1	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.10210472000045534	[223]	[220,199,208,265]	1	hSpCas9	negative selection	6175587
82867275	82867298	4	+	27260156	CADOES1	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.9031267603304227	[365]	[187,175,208,153]	-9	hSpCas9	negative selection	6175588
82870368	82870391	4	+	27260156	CADOES1	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.1999185960940903	[360]	[281,274,375,233]	-3	hSpCas9	negative selection	6239840
82870368	82870391	4	-	27260156	CADOES1	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.6178964513559366	[654]	[324,385,453,423]	-8	hSpCas9	negative selection	6239841
82866920	82866943	4	-	27260156	CADOES1	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.012416348484910245	[1367]	[1248,1093,1325,1470]	0	hSpCas9	negative selection	6239842
82867222	82867245	4	-	27260156	EWS502	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5435072517426394	[1106]	[1353,1542,1765,2255]	8	hSpCas9	negative selection	6296837
82866838	82866861	4	-	27260156	EWS502	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.2816469663139418	[223]	[237,191,136,207]	-5	hSpCas9	negative selection	6296838
82867275	82867298	4	+	27260156	EWS502	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-1.4742268072871987	[365]	[123,88,233,113]	-9	hSpCas9	negative selection	6296839
82870368	82870391	4	+	27260156	EWS502	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.06710049518887895	[360]	[390,503,304,395]	1	hSpCas9	negative selection	6361091
82870368	82870391	4	-	27260156	EWS502	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.6975237386480375	[654]	[388,431,458,434]	-8	hSpCas9	negative selection	6361092
82866920	82866943	4	-	27260156	EWS502	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.18797437414158447	[1367]	[1532,1349,1864,1894]	3	hSpCas9	negative selection	6361093
82867222	82867245	4	-	27260156	EW8	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5281486346975435	[1106]	[1553,1123,1150,1393]	8	hSpCas9	negative selection	6418088
82866838	82866861	4	-	27260156	EW8	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.14121792433463987	[223]	[134,224,116,185]	-3	hSpCas9	negative selection	6418089
82867275	82867298	4	+	27260156	EW8	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.7563896257799565	[365]	[218,196,132,164]	-8	hSpCas9	negative selection	6418090
82870368	82870391	4	+	27260156	EW8	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.05629207242937295	[360]	[333,306,269,313]	1	hSpCas9	negative selection	6482342
82870368	82870391	4	-	27260156	EW8	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.35735196093756516	[654]	[400,400,375,482]	-6	hSpCas9	negative selection	6482343
82866920	82866943	4	-	27260156	EW8	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.2548068986977905	[1367]	[1419,1625,912,1409]	5	hSpCas9	negative selection	6482344
82867222	82867245	4	-	27260156	CORL105	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.43124180885424845	[1106]	[1724,1742,1838,1695]	7	hSpCas9	negative selection	6539339
82866838	82866861	4	-	27260156	CORL105	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.5512205984031653	[223]	[414,323,477,336]	8	hSpCas9	negative selection	6539340
82867275	82867298	4	+	27260156	CORL105	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.15228108589817113	[365]	[373,333,532,324]	-3	hSpCas9	negative selection	6539341
82870368	82870391	4	+	27260156	CORL105	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.1387387099368909	[360]	[437,380,455,273]	-3	hSpCas9	negative selection	6603593
82870368	82870391	4	-	27260156	CORL105	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	0.18640598171104938	[654]	[825,636,1023,1028]	3	hSpCas9	negative selection	6603594
82866920	82866943	4	-	27260156	CORL105	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.20559500296582311	[1367]	[1951,1697,2347,1474]	4	hSpCas9	negative selection	6603595
82867222	82867245	4	-	27260156	HS294T	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.39391850879769486	[1106]	[607,548,502,587]	5	hSpCas9	negative selection	6660590
82866838	82866861	4	-	27260156	HS294T	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.11594195923556305	[223]	[105,77,83,108]	1	hSpCas9	negative selection	6660591
82867275	82867298	4	+	27260156	HS294T	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.5469395361381895	[365]	[44,68,122,167]	-7	hSpCas9	negative selection	6660592
82870368	82870391	4	+	27260156	HS294T	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.3011661889206268	[360]	[223,242,89,112]	4	hSpCas9	negative selection	6724844
82870368	82870391	4	-	27260156	HS294T	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.0890501179378726	[654]	[306,194,252,181]	-1	hSpCas9	negative selection	6724845
82866920	82866943	4	-	27260156	HS294T	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.0058946736438962866	[1367]	[585,465,498,575]	0	hSpCas9	negative selection	6724846
82867222	82867245	4	-	27260156	HCC44	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.7095061947743664	[1106]	[2025,1716,2110,2363]	9	hSpCas9	negative selection	6781841
82866838	82866861	4	-	27260156	HCC44	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.16342572259043464	[223]	[327,79,576,232]	2	hSpCas9	negative selection	6781842
82867275	82867298	4	+	27260156	HCC44	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.14092896393968535	[365]	[225,313,414,539]	-2	hSpCas9	negative selection	6781843
82870368	82870391	4	+	27260156	HCC44	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.045351174804464156	[360]	[372,381,710,271]	0	hSpCas9	negative selection	6846095
82870368	82870391	4	-	27260156	HCC44	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.044623492145412724	[654]	[530,617,907,835]	0	hSpCas9	negative selection	6846096
82866920	82866943	4	-	27260156	HCC44	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.24323255890302775	[1367]	[1636,1494,2228,2040]	4	hSpCas9	negative selection	6846097
82867222	82867245	4	-	27260156	G402	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.9665211981524073	[1106]	[2767,3167,2461,2219]	9	hSpCas9	negative selection	6903092
82866838	82866861	4	-	27260156	G402	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.11569163518555581	[223]	[438,244,324,196]	1	hSpCas9	negative selection	6903093
82867275	82867298	4	+	27260156	G402	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-1.0442224047163067	[365]	[370,82,210,214]	-8	hSpCas9	negative selection	6903094
82870368	82870391	4	+	27260156	G402	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.4375266687651282	[360]	[615,641,336,784]	5	hSpCas9	negative selection	6967346
82870368	82870391	4	-	27260156	G402	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.014266867039501752	[654]	[963,576,908,727]	0	hSpCas9	negative selection	6967347
82866920	82866943	4	-	27260156	G402	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.4858685667598184	[1367]	[2720,2921,2428,1404]	6	hSpCas9	negative selection	6967348
82867222	82867245	4	-	27260156	L33	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.16411076792693136	[1106]	[1249,527,816,1123]	3	hSpCas9	negative selection	7024343
82866838	82866861	4	-	27260156	L33	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.37696102320637803	[223]	[286,120,177,297]	7	hSpCas9	negative selection	7024344
82867275	82867298	4	+	27260156	L33	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	0.03934558095087154	[365]	[383,183,227,308]	0	hSpCas9	negative selection	7024345
82870368	82870391	4	+	27260156	L33	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.3937591504654466	[360]	[270,90,220,254]	-7	hSpCas9	negative selection	7088597
82870368	82870391	4	-	27260156	L33	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.10847507895842784	[654]	[685,272,410,423]	-2	hSpCas9	negative selection	7088598
82866920	82866943	4	-	27260156	L33	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.18645451846163308	[1367]	[1251,486,678,1284]	-4	hSpCas9	negative selection	7088599
82867222	82867245	4	-	27260156	K562	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.475098490468143	[1106]	[1387,1749,641,1662]	6	hSpCas9	negative selection	7145594
82866838	82866861	4	-	27260156	K562	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.28781761480555557	[223]	[105,171,172,191]	-4	hSpCas9	negative selection	7145595
82867275	82867298	4	+	27260156	K562	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.7862114476069393	[365]	[236,180,204,138]	-7	hSpCas9	negative selection	7145596
82870368	82870391	4	+	27260156	K562	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.11675430637494794	[360]	[238,311,284,335]	-1	hSpCas9	negative selection	7209848
82870368	82870391	4	-	27260156	K562	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.36665669153373276	[654]	[648,503,382,301]	-4	hSpCas9	negative selection	7209849
82866920	82866943	4	-	27260156	K562	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.34972556248870545	[1367]	[1398,1121,2172,1462]	4	hSpCas9	negative selection	7209850
82867222	82867245	4	-	27260156	HT29	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5313282016707277	[1106]	[2206,1780,2328,1508]	8	hSpCas9	negative selection	7266845
82866838	82866861	4	-	27260156	HT29	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.509097604720867	[223]	[500,333,450,278]	8	hSpCas9	negative selection	7266846
82867275	82867298	4	+	27260156	HT29	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.7365638008109563	[365]	[250,257,259,291]	-8	hSpCas9	negative selection	7266847
82870368	82870391	4	+	27260156	HT29	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.016265151727140326	[360]	[552,534,406,309]	0	hSpCas9	negative selection	7331099
82870368	82870391	4	-	27260156	HT29	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.2520945452937169	[654]	[562,695,810,601]	-5	hSpCas9	negative selection	7331100
82866920	82866943	4	-	27260156	HT29	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.15393943055332193	[1367]	[2134,2009,1885,1442]	3	hSpCas9	negative selection	7331101
82867222	82867245	4	-	27260156	MHHES1	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.31727736475885604	[1106]	[1625,1962,1250,1417]	6	hSpCas9	negative selection	7388096
82866838	82866861	4	-	27260156	MHHES1	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.22086659855603608	[223]	[244,302,262,91]	-4	hSpCas9	negative selection	7388097
82867275	82867298	4	+	27260156	MHHES1	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.9350641976464775	[365]	[221,194,212,223]	-9	hSpCas9	negative selection	7388098
82870368	82870391	4	+	27260156	MHHES1	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.10155263637303896	[360]	[513,497,404,352]	2	hSpCas9	negative selection	7452350
82870368	82870391	4	-	27260156	MHHES1	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.7434189044242199	[654]	[597,567,390,267]	-8	hSpCas9	negative selection	7452351
82866920	82866943	4	-	27260156	MHHES1	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.29441410361689613	[1367]	[2135,1882,2055,1549]	5	hSpCas9	negative selection	7452352
82867222	82867245	4	-	27260156	MEWO	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.46505106093367865	[1106]	[1704,1190,1446]	8	hSpCas9	negative selection	7509347
82866838	82866861	4	-	27260156	MEWO	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.09562627647947486	[223]	[233,158,280]	2	hSpCas9	negative selection	7509348
82867275	82867298	4	+	27260156	MEWO	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.12105538226928575	[365]	[285,295,356]	-3	hSpCas9	negative selection	7509349
82870368	82870391	4	+	27260156	MEWO	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.14236827594971452	[360]	[342,326,254]	-3	hSpCas9	negative selection	7573601
82870368	82870391	4	-	27260156	MEWO	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.43745077527612497	[654]	[455,473,427]	-7	hSpCas9	negative selection	7573602
82866920	82866943	4	-	27260156	MEWO	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.04974987137818965	[1367]	[1441,1224,1081]	-1	hSpCas9	negative selection	7573603
82867222	82867245	4	-	27260156	LNCAPCLONEFGC	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5508188825857148	[1106]	[1377,1478,1636,1406]	8	hSpCas9	negative selection	7630598
82866838	82866861	4	-	27260156	LNCAPCLONEFGC	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.18500663634184744	[223]	[320,113,260,236]	3	hSpCas9	negative selection	7630599
82867275	82867298	4	+	27260156	LNCAPCLONEFGC	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.5623644015321043	[365]	[187,128,298,299]	-7	hSpCas9	negative selection	7630600
82870368	82870391	4	+	27260156	LNCAPCLONEFGC	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.329668896275522	[360]	[344,591,377,312]	5	hSpCas9	negative selection	7694852
82870368	82870391	4	-	27260156	LNCAPCLONEFGC	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.26617056749854945	[654]	[468,512,598,406]	-4	hSpCas9	negative selection	7694853
82866920	82866943	4	-	27260156	LNCAPCLONEFGC	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.08300678366669012	[1367]	[1418,1098,1510,1261]	1	hSpCas9	negative selection	7694854
82867222	82867245	4	-	27260156	PANC0327	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.525665977579068	[1106]	[1963,959,1455,1385]	7	hSpCas9	negative selection	7751849
82866838	82866861	4	-	27260156	PANC0327	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.35318932833618977	[223]	[135,398,138,313]	5	hSpCas9	negative selection	7751850
82867275	82867298	4	+	27260156	PANC0327	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-1.1410086053572215	[365]	[97,168,232,82]	-8	hSpCas9	negative selection	7751851
82870368	82870391	4	+	27260156	PANC0327	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.18170974293019063	[360]	[445,274,377,373]	2	hSpCas9	negative selection	7816103
82870368	82870391	4	-	27260156	PANC0327	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.9278963447734272	[654]	[414,285,393,139]	-8	hSpCas9	negative selection	7816104
82866920	82866943	4	-	27260156	PANC0327	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.22692936487166726	[1367]	[1427,1029,1334,1945]	3	hSpCas9	negative selection	7816105
82867222	82867245	4	-	27260156	NCIH2009	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.583390728839692	[1106]	[3273,1958,1910]	7	hSpCas9	negative selection	7873100
82866838	82866861	4	-	27260156	NCIH2009	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.647543635757736	[223]	[428,590,435]	8	hSpCas9	negative selection	7873101
82867275	82867298	4	+	27260156	NCIH2009	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.5985437093318832	[365]	[435,226,370]	-6	hSpCas9	negative selection	7873102
82870368	82870391	4	+	27260156	NCIH2009	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.21191483982525666	[360]	[628,440,692]	3	hSpCas9	negative selection	7937354
82870368	82870391	4	-	27260156	NCIH2009	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.2670453274230121	[654]	[845,710,740]	-4	hSpCas9	negative selection	7937355
82866920	82866943	4	-	27260156	NCIH2009	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.05432129930748553	[1367]	[1970,1767,1806]	0	hSpCas9	negative selection	7937356
82867222	82867245	4	-	27260156	NCIH1373	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.8191448631687701	[1106]	[2025,1586,2424,729]	7	hSpCas9	negative selection	7994351
82866838	82866861	4	-	27260156	NCIH1373	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.10746245876299954	[223]	[242,409,185,57]	1	hSpCas9	negative selection	7994352
82867275	82867298	4	+	27260156	NCIH1373	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-1.488624177281448	[365]	[196,146,110,35]	-9	hSpCas9	negative selection	7994353
82870368	82870391	4	+	27260156	NCIH1373	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.547438398595583	[360]	[695,492,350,228]	5	hSpCas9	negative selection	8058605
82870368	82870391	4	-	27260156	NCIH1373	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.3698817045284195	[654]	[642,305,592,204]	-4	hSpCas9	negative selection	8058606
82866920	82866943	4	-	27260156	NCIH1373	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.5933890946011104	[1367]	[2513,2008,1954,753]	6	hSpCas9	negative selection	8058607
82867222	82867245	4	-	27260156	PATU8902	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	1.1539068016885838	[1106]	[3466,3184,3777,3137]	9	hSpCas9	negative selection	8115602
82866838	82866861	4	-	27260156	PATU8902	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.3250182030586304	[223]	[641,351,118,530]	3	hSpCas9	negative selection	8115603
82867275	82867298	4	+	27260156	PATU8902	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.8446082216941173	[365]	[164,327,271,384]	-7	hSpCas9	negative selection	8115604
82870368	82870391	4	+	27260156	PATU8902	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.09984971322343617	[360]	[334,702,495,315]	-1	hSpCas9	negative selection	8179856
82870368	82870391	4	-	27260156	PATU8902	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.7621428299374343	[654]	[627,597,604,264]	-6	hSpCas9	negative selection	8179857
82866920	82866943	4	-	27260156	PATU8902	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.39796191370665013	[1367]	[2622,2639,2086,2816]	4	hSpCas9	negative selection	8179858
82867222	82867245	4	-	27260156	PANC1	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.6447696939857832	[1106]	[1412,1806,1762,1076]	9	hSpCas9	negative selection	8236853
82866838	82866861	4	-	27260156	PANC1	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.3488938537584565	[223]	[273,262,165,270]	5	hSpCas9	negative selection	8236854
82867275	82867298	4	+	27260156	PANC1	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.6365553627959603	[365]	[209,288,243,97]	-7	hSpCas9	negative selection	8236855
82870368	82870391	4	+	27260156	PANC1	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.25236915749431665	[360]	[380,430,400,284]	4	hSpCas9	negative selection	8301107
82870368	82870391	4	-	27260156	PANC1	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.39868948441764185	[654]	[424,482,435,375]	-6	hSpCas9	negative selection	8301108
82866920	82866943	4	-	27260156	PANC1	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.04995012537173693	[1367]	[1076,1568,1134,1149]	0	hSpCas9	negative selection	8301109
82867222	82867245	4	-	27260156	PANC0813	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.504008078562155	[1106]	[2051,1807,1727,1805]	7	hSpCas9	negative selection	8358104
82866838	82866861	4	-	27260156	PANC0813	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.402000180435669	[223]	[471,214,370,343]	6	hSpCas9	negative selection	8358105
82867275	82867298	4	+	27260156	PANC0813	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.5152626989802318	[365]	[235,307,129,509]	-7	hSpCas9	negative selection	8358106
82870368	82870391	4	+	27260156	PANC0813	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.07773793204001733	[360]	[461,417,402,332]	-1	hSpCas9	negative selection	8422358
82870368	82870391	4	-	27260156	PANC0813	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.4833394601871889	[654]	[511,441,817,432]	-6	hSpCas9	negative selection	8422359
82866920	82866943	4	-	27260156	PANC0813	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.03285969363354102	[1367]	[1784,1603,1425,1488]	0	hSpCas9	negative selection	8422360
82867222	82867245	4	-	27260156	RDES	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.6981749643883355	[1106]	[1761,1744,2440,2414]	9	hSpCas9	negative selection	8479355
82866838	82866861	4	-	27260156	RDES	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.20247622028663215	[223]	[212,238,257,171]	-3	hSpCas9	negative selection	8479356
82867275	82867298	4	+	27260156	RDES	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.6522571038468068	[365]	[224,211,325,325]	-8	hSpCas9	negative selection	8479357
82870368	82870391	4	+	27260156	RDES	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.44833547036499444	[360]	[413,594,517,783]	7	hSpCas9	negative selection	8543609
82870368	82870391	4	-	27260156	RDES	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.376095457685919	[654]	[426,675,562,675]	-6	hSpCas9	negative selection	8543610
82866920	82866943	4	-	27260156	RDES	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.08058482272655243	[1367]	[1367,1728,1645,1961]	1	hSpCas9	negative selection	8543611
82867222	82867245	4	-	27260156	PC3	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.3495444231953526	[1106]	[1081,1344,2043,1379]	7	hSpCas9	negative selection	8600606
82866838	82866861	4	-	27260156	PC3	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.19586597151214358	[223]	[256,173,417,200]	4	hSpCas9	negative selection	8600607
82867275	82867298	4	+	27260156	PC3	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.0344808635573145	[365]	[271,339,553,330]	-1	hSpCas9	negative selection	8600608
82870368	82870391	4	+	27260156	PC3	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.21664268570226547	[360]	[285,212,523,270]	-5	hSpCas9	negative selection	8664860
82870368	82870391	4	-	27260156	PC3	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.6885110001201366	[654]	[206,539,531,436]	-9	hSpCas9	negative selection	8664861
82866920	82866943	4	-	27260156	PC3	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.1338043843154053	[1367]	[751,1415,2625,1857]	3	hSpCas9	negative selection	8664862
82867222	82867245	4	-	27260156	PATU8988T	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5218818385896589	[1106]	[1450,2258,1273,1203]	8	hSpCas9	negative selection	8721857
82866838	82866861	4	-	27260156	PATU8988T	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.12722487955283546	[223]	[245,194,192,154]	-2	hSpCas9	negative selection	8721858
82867275	82867298	4	+	27260156	PATU8988T	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.6136015991215173	[365]	[195,375,149,215]	-7	hSpCas9	negative selection	8721859
82870368	82870391	4	+	27260156	PATU8988T	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.09696788622724911	[360]	[122,453,219,537]	-2	hSpCas9	negative selection	8786111
82870368	82870391	4	-	27260156	PATU8988T	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-1.118486846467893	[654]	[201,374,271,327]	-9	hSpCas9	negative selection	8786112
82866920	82866943	4	-	27260156	PATU8988T	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.031599822818748624	[1367]	[1195,1289,1265,1431]	0	hSpCas9	negative selection	8786113
82867222	82867245	4	-	27260156	T47D	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.45341932164434784	[1106]	[1612,1603,1870,1993]	8	hSpCas9	negative selection	8843108
82866838	82866861	4	-	27260156	T47D	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.22818953050264634	[223]	[298,276,311,337]	5	hSpCas9	negative selection	8843109
82867275	82867298	4	+	27260156	T47D	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.5870825470570793	[365]	[305,222,285,326]	-8	hSpCas9	negative selection	8843110
82870368	82870391	4	+	27260156	T47D	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.11227303314987025	[360]	[441,419,430,530]	2	hSpCas9	negative selection	8907362
82870368	82870391	4	-	27260156	T47D	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.2070572767004889	[654]	[652,692,665,627]	-4	hSpCas9	negative selection	8907363
82866920	82866943	4	-	27260156	T47D	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.14021750020413792	[1367]	[1750,1703,1724,1852]	3	hSpCas9	negative selection	8907364
82867222	82867245	4	-	27260156	SU8686	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.5031951647882376	[1106]	[1320,1493,1725,1738]	8	hSpCas9	negative selection	8964359
82866838	82866861	4	-	27260156	SU8686	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.16806269239095972	[223]	[186,332,213,258]	3	hSpCas9	negative selection	8964360
82867275	82867298	4	+	27260156	SU8686	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.9489489515054768	[365]	[197,194,121,239]	-8	hSpCas9	negative selection	8964361
82870368	82870391	4	+	27260156	SU8686	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.2781486162833029	[360]	[404,401,414,533]	5	hSpCas9	negative selection	9028613
82870368	82870391	4	-	27260156	SU8686	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.11323959808759293	[654]	[711,512,585,580]	-2	hSpCas9	negative selection	9028614
82866920	82866943	4	-	27260156	SU8686	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	-0.08052197440459574	[1367]	[1176,1154,1255,1614]	-1	hSpCas9	negative selection	9028615
82867222	82867245	4	-	27260156	SKES1	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.29370096156764447	[1106]	[1483,1476,1183,1296]	6	hSpCas9	negative selection	9085610
82866838	82866861	4	-	27260156	SKES1	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	-0.04026956291566686	[223]	[237,289,179,175]	-1	hSpCas9	negative selection	9085611
82867275	82867298	4	+	27260156	SKES1	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.41732861806930766	[365]	[366,330,230,191]	-7	hSpCas9	negative selection	9085612
82870368	82870391	4	+	27260156	SKES1	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.28402196116261763	[360]	[338,397,553,437]	6	hSpCas9	negative selection	9149864
82870368	82870391	4	-	27260156	SKES1	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.15003025643763152	[654]	[451,751,648,505]	-3	hSpCas9	negative selection	9149865
82866920	82866943	4	-	27260156	SKES1	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.11132850654196647	[1367]	[1445,1869,1513,1134]	2	hSpCas9	negative selection	9149866
82867222	82867245	4	-	27260156	TOV112D	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.44310294302805775	[1106]	[1546,1779,1434,1339]	7	hSpCas9	negative selection	9206861
82866838	82866861	4	-	27260156	TOV112D	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.2897565869828158	[223]	[260,602,170,144]	5	hSpCas9	negative selection	9206862
82867275	82867298	4	+	27260156	TOV112D	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	0.08689403585274358	[365]	[338,509,375,357]	1	hSpCas9	negative selection	9206863
82870368	82870391	4	+	27260156	TOV112D	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.4892086186431504	[360]	[227,260,308,230]	-7	hSpCas9	negative selection	9271115
82870368	82870391	4	-	27260156	TOV112D	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.5021938777184636	[654]	[391,616,419,454]	-7	hSpCas9	negative selection	9271116
82866920	82866943	4	-	27260156	TOV112D	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.15541390243022146	[1367]	[1821,1633,1285,1413]	3	hSpCas9	negative selection	9271117
82867222	82867245	4	-	27260156	TC71	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.3128561350935515	[1106]	[1492,1423,1368,1621]	7	hSpCas9	negative selection	9328112
82866838	82866861	4	-	27260156	TC71	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.6071495890900938	[223]	[315,383,377,386]	9	hSpCas9	negative selection	9328113
82867275	82867298	4	+	27260156	TC71	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.22080764725386393	[365]	[397,309,344,288]	-5	hSpCas9	negative selection	9328114
82870368	82870391	4	+	27260156	TC71	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	-0.2002740663403076	[360]	[375,262,401,300]	-5	hSpCas9	negative selection	9392366
82870368	82870391	4	-	27260156	TC71	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.11853897260126278	[654]	[605,661,651,668]	-3	hSpCas9	negative selection	9392367
82866920	82866943	4	-	27260156	TC71	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.04591707633785802	[1367]	[1489,1597,1342,1637]	1	hSpCas9	negative selection	9392368
82867222	82867245	4	-	27260156	TC32	viability	TTATCAGCTGCTTCGTTTGATGG	SEC31A	ENSG00000138674	0.7553929411195663	[1106]	[1495,1586,1945,2030]	9	hSpCas9	negative selection	9449363
82866838	82866861	4	-	27260156	TC32	viability	CTCTGAAGAAGCCGCCCAAGTGG	SEC31A	ENSG00000138674	0.1890041830798611	[223]	[183,252,190,313]	3	hSpCas9	negative selection	9449364
82867275	82867298	4	+	27260156	TC32	viability	ATCGAAGCACCACTGTGTGTTGG	SEC31A	ENSG00000138674	-0.8400145032815665	[365]	[200,133,260,193]	-9	hSpCas9	negative selection	9449365
82870368	82870391	4	+	27260156	TC32	viability	CCACAGCTCAGTAACAATTCAGG	SEC31A	ENSG00000138674	0.2960715252312469	[360]	[297,276,565,606]	5	hSpCas9	negative selection	9513617
82870368	82870391	4	-	27260156	TC32	viability	CCTGAATTGTTACTGAGCTGTGG	SEC31A	ENSG00000138674	-0.07524703763457219	[654]	[532,422,633,800]	-1	hSpCas9	negative selection	9513618
82866920	82866943	4	-	27260156	TC32	viability	AATCTTGATCCCTTTGGCACAGG	SEC31A	ENSG00000138674	0.3347372067523484	[1367]	[1680,1308,1720,1810]	6	hSpCas9	negative selection	9513619
82867284	82867307	4	-	27869803	HPAFII	viability after 27 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.6607939136808021	[440]	[377,356,NaN]	5	hSpCas9	negative selection	9589072
82874662	82874685	4	+	27869803	HPAFII	viability after 27 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.9593731697827357	[101]	[172,46,NaN]	7	hSpCas9	negative selection	9589073
82878854	82878877	4	-	27869803	HPAFII	viability after 27 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.6993933219984045	[205]	[432,283,NaN]	9	hSpCas9	negative selection	9589074
82880789	82880812	4	+	27869803	HPAFII	viability after 27 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.7581863434788075	[246]	[103,315,NaN]	6	hSpCas9	negative selection	9589075
82881895	82881918	4	-	27869803	HPAFII	viability after 27 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.519810955560899	[407]	[222,377,NaN]	4	hSpCas9	negative selection	9589076
82891114	82891137	4	-	27869803	HPAFII	viability after 27 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.7900769306257683	[389]	[473,254,NaN]	6	hSpCas9	negative selection	9589077
82867284	82867307	4	-	27869803	HPAFII	viability after 15 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.330422529294244	[440]	[701,529,NaN]	4	hSpCas9	negative selection	9671521
82874662	82874685	4	+	27869803	HPAFII	viability after 15 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.5960886200919286	[101]	[235,121,NaN]	6	hSpCas9	negative selection	9671522
82878854	82878877	4	-	27869803	HPAFII	viability after 15 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.9531999560082187	[205]	[834,175,NaN]	9	hSpCas9	negative selection	9671523
82880789	82880812	4	+	27869803	HPAFII	viability after 15 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.05771518028473546	[246]	[205,319,NaN]	0	hSpCas9	negative selection	9671524
82881895	82881918	4	-	27869803	HPAFII	viability after 15 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.09473283358163265	[407]	[639,267,NaN]	-1	hSpCas9	negative selection	9671525
82891114	82891137	4	-	27869803	HPAFII	viability after 15 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	0.3741279790923254	[389]	[734,423,NaN]	4	hSpCas9	negative selection	9671526
82867284	82867307	4	-	27869803	ASPC1	viability after 36 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.3022804165786013	[1148]	[666,775,144]	3	hSpCas9	negative selection	9753970
82874662	82874685	4	+	27869803	ASPC1	viability after 36 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	-0.1330584215925874	[265]	[129,129,15]	-1	hSpCas9	negative selection	9753971
82878854	82878877	4	-	27869803	ASPC1	viability after 36 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.1464700640522638	[540]	[508,204,518]	9	hSpCas9	negative selection	9753972
82880789	82880812	4	+	27869803	ASPC1	viability after 36 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	1.2841697961932617	[601]	[775,434,381]	9	hSpCas9	negative selection	9753973
82881895	82881918	4	-	27869803	ASPC1	viability after 36 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.9735457450374536	[735]	[517,483,505]	8	hSpCas9	negative selection	9753974
82891114	82891137	4	-	27869803	ASPC1	viability after 36 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.1859392174778276	[1184]	[491,288,328]	-2	hSpCas9	negative selection	9753975
82867284	82867307	4	-	27869803	PATU8988S	viability after 35 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.05910448416611502	[848]	[200,455,NaN]	0	hSpCas9	negative selection	9836419
82874662	82874685	4	+	27869803	PATU8988S	viability after 35 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.2564264365614082	[260]	[307,193,NaN]	9	hSpCas9	negative selection	9836420
82878854	82878877	4	-	27869803	PATU8988S	viability after 35 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.5440599324004779	[552]	[211,437,NaN]	6	hSpCas9	negative selection	9836421
82880789	82880812	4	+	27869803	PATU8988S	viability after 35 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.5073038491959818	[578]	[189,137,NaN]	-5	hSpCas9	negative selection	9836422
82881895	82881918	4	-	27869803	PATU8988S	viability after 35 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.4642838330315112	[739]	[226,204,NaN]	-5	hSpCas9	negative selection	9836423
82891114	82891137	4	-	27869803	PATU8988S	viability after 35 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.11672720447447182	[1023]	[538,220,NaN]	-1	hSpCas9	negative selection	9836424
82867284	82867307	4	-	27869803	PATU8988S	viability after 31 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.34645747485652534	[848]	[172,384,NaN]	-4	hSpCas9	negative selection	9918868
82874662	82874685	4	+	27869803	PATU8988S	viability after 31 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	1.015421475456634	[260]	[117,327,NaN]	9	hSpCas9	negative selection	9918869
82878854	82878877	4	-	27869803	PATU8988S	viability after 31 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	0.37267272728948464	[552]	[182,415,NaN]	4	hSpCas9	negative selection	9918870
82880789	82880812	4	+	27869803	PATU8988S	viability after 31 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.6910123802605145	[578]	[175,100,NaN]	-6	hSpCas9	negative selection	9918871
82881895	82881918	4	-	27869803	PATU8988S	viability after 31 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	-0.027443880926708242	[739]	[241,349,NaN]	0	hSpCas9	negative selection	9918872
82891114	82891137	4	-	27869803	PATU8988S	viability after 31 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	-0.1407108754426133	[1023]	[416,310,NaN]	-1	hSpCas9	negative selection	9918873
82867284	82867307	4	-	27869803	HPAFII	viability after 35 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.2533148370212406	[440]	[243,290,NaN]	1	hSpCas9	negative selection	10001317
82874662	82874685	4	+	27869803	HPAFII	viability after 35 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.41122891854177956	[101]	[110,20,NaN]	2	hSpCas9	negative selection	10001318
82878854	82878877	4	-	27869803	HPAFII	viability after 35 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	1.9560842850941635	[205]	[509,285,NaN]	9	hSpCas9	negative selection	10001319
82880789	82880812	4	+	27869803	HPAFII	viability after 35 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	-0.17253080988242592	[246]	[6,227,NaN]	-1	hSpCas9	negative selection	10001320
82881895	82881918	4	-	27869803	HPAFII	viability after 35 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.3984043220968103	[407]	[164,392,NaN]	2	hSpCas9	negative selection	10001321
82891114	82891137	4	-	27869803	HPAFII	viability after 35 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	1.130279196982022	[389]	[577,267,NaN]	7	hSpCas9	negative selection	10001322
82867284	82867307	4	-	27869803	HPAFII	viability after 31 days	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5187269573306394	[440]	[389,315,NaN]	4	hSpCas9	negative selection	10083766
82874662	82874685	4	+	27869803	HPAFII	viability after 31 days	CCATACAGTGGCCCGGCCACTGG	SEC31A	ENSG00000138674	0.1635198013675887	[101]	[88,36,NaN]	1	hSpCas9	negative selection	10083767
82878854	82878877	4	-	27869803	HPAFII	viability after 31 days	TCTGGAGTTCTGATTGCAGGTGG	SEC31A	ENSG00000138674	2.142920400011796	[205]	[657,349,NaN]	9	hSpCas9	negative selection	10083768
82880789	82880812	4	+	27869803	HPAFII	viability after 31 days	AACCTCATACCTGTGAGAAGAGG	SEC31A	ENSG00000138674	0.2680293307161798	[246]	[86,253,NaN]	2	hSpCas9	negative selection	10083769
82881895	82881918	4	-	27869803	HPAFII	viability after 31 days	ATCGTACAGCCATGCAGGCATGG	SEC31A	ENSG00000138674	0.32936726855568654	[407]	[213,367,NaN]	2	hSpCas9	negative selection	10083770
82891114	82891137	4	-	27869803	HPAFII	viability after 31 days	GACGAGCGCTGCACTAACGCAGG	SEC31A	ENSG00000138674	1.3040010249174188	[389]	[750,310,NaN]	8	hSpCas9	negative selection	10083771
82864460	82864483	4	+	28162770	P31FUJ	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.4541600098091728	[181]	[292]	5	hSpCas9	negative selection	10231421
82857715	82857738	4	-	28162770	P31FUJ	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.016733746377158187	[518]	[616]	0	hSpCas9	negative selection	10231422
82853656	82853679	4	+	28162770	P31FUJ	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.9970653374842158	[274]	[644]	9	hSpCas9	negative selection	10231423
82851547	82851570	4	-	28162770	P31FUJ	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.44121148412390576	[177]	[283]	5	hSpCas9	negative selection	10231424
82851440	82851463	4	+	28162770	P31FUJ	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.7062687969432897	[132]	[254]	7	hSpCas9	negative selection	10231425
82848871	82848894	4	-	28162770	P31FUJ	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.5394635426484305	[187]	[151]	-4	hSpCas9	negative selection	10231426
82848827	82848850	4	+	28162770	P31FUJ	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.321041085927938	[452]	[664]	3	hSpCas9	negative selection	10231427
82874729	82874752	4	+	28162770	P31FUJ	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.5483040301423077	[55]	[44]	-4	hSpCas9	negative selection	10231428
82867284	82867307	4	-	28162770	P31FUJ	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.409679966498458	[155]	[137]	-4	hSpCas9	negative selection	10231429
82866893	82866916	4	+	28162770	P31FUJ	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.1467864588601756	[102]	[133]	1	hSpCas9	negative selection	10231430
82864460	82864483	4	+	28162770	TF1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10400787
82857715	82857738	4	-	28162770	TF1	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10400788
82853656	82853679	4	+	28162770	TF1	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10400789
82851547	82851570	4	-	28162770	TF1	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10400790
82851440	82851463	4	+	28162770	TF1	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10400791
82848871	82848894	4	-	28162770	TF1	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10400792
82848827	82848850	4	+	28162770	TF1	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	NaN	[NaN]	[361]	1	hSpCas9	negative selection	10400793
82874729	82874752	4	+	28162770	TF1	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10400794
82867284	82867307	4	-	28162770	TF1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10400795
82866893	82866916	4	+	28162770	TF1	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10400796
82864460	82864483	4	+	28162770	SKM1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.30460248111348387	[50]	[72]	-3	hSpCas9	negative selection	10570153
82857715	82857738	4	-	28162770	SKM1	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.21628063713405188	[114]	[174]	-2	hSpCas9	negative selection	10570154
82853656	82853679	4	+	28162770	SKM1	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.222392421336448	[95]	[197]	2	hSpCas9	negative selection	10570155
82851547	82851570	4	-	28162770	SKM1	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.49188907779993857	[71]	[178]	5	hSpCas9	negative selection	10570156
82851440	82851463	4	+	28162770	SKM1	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.5714582363714086	[57]	[68]	-4	hSpCas9	negative selection	10570157
82848871	82848894	4	-	28162770	SKM1	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	0.22429195425192944	[45]	[94]	2	hSpCas9	negative selection	10570158
82848827	82848850	4	+	28162770	SKM1	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.6421064078247649	[111]	[308]	6	hSpCas9	negative selection	10570159
82874729	82874752	4	+	28162770	SKM1	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10570160
82867284	82867307	4	-	28162770	SKM1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-1.4069641987431618	[32]	[21]	-7	hSpCas9	negative selection	10570161
82866893	82866916	4	+	28162770	SKM1	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.07725875326407994	[36]	[61]	0	hSpCas9	negative selection	10570162
82864460	82864483	4	+	28162770	SKM1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.30460248111348387	[50]	[72]	-3	hSpCas9	negative selection	10739519
82857715	82857738	4	-	28162770	SKM1	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.21628063713405188	[114]	[174]	-2	hSpCas9	negative selection	10739520
82853656	82853679	4	+	28162770	SKM1	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.222392421336448	[95]	[197]	2	hSpCas9	negative selection	10739521
82851547	82851570	4	-	28162770	SKM1	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.49188907779993857	[71]	[178]	5	hSpCas9	negative selection	10739522
82851440	82851463	4	+	28162770	SKM1	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.5714582363714086	[57]	[68]	-4	hSpCas9	negative selection	10739523
82848871	82848894	4	-	28162770	SKM1	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	0.22429195425192944	[45]	[94]	2	hSpCas9	negative selection	10739524
82848827	82848850	4	+	28162770	SKM1	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.6421064078247649	[111]	[308]	6	hSpCas9	negative selection	10739525
82874729	82874752	4	+	28162770	SKM1	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10739526
82867284	82867307	4	-	28162770	SKM1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-1.4069641987431618	[32]	[21]	-7	hSpCas9	negative selection	10739527
82866893	82866916	4	+	28162770	SKM1	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.07725875326407994	[36]	[61]	0	hSpCas9	negative selection	10739528
82864460	82864483	4	+	28162770	PL21	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-1.0827943487821785	[145]	[29]	-6	hSpCas9	negative selection	10908885
82857715	82857738	4	-	28162770	PL21	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.5795942652826196	[387]	[112]	-4	hSpCas9	negative selection	10908886
82853656	82853679	4	+	28162770	PL21	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.012988198936411344	[336]	[147]	0	hSpCas9	negative selection	10908887
82851547	82851570	4	-	28162770	PL21	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.32872382055073324	[235]	[128]	3	hSpCas9	negative selection	10908888
82851440	82851463	4	+	28162770	PL21	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-2.4243512504184737	[258]	[20]	-9	hSpCas9	negative selection	10908889
82848871	82848894	4	-	28162770	PL21	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.9487237714251624	[203]	[45]	-6	hSpCas9	negative selection	10908890
82848827	82848850	4	+	28162770	PL21	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.7572679070137507	[313]	[230]	6	hSpCas9	negative selection	10908891
82874729	82874752	4	+	28162770	PL21	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.022252806847127715	[27]	[11]	0	hSpCas9	negative selection	10908892
82867284	82867307	4	-	28162770	PL21	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.25929200414797715	[131]	[47]	-2	hSpCas9	negative selection	10908893
82866893	82866916	4	+	28162770	PL21	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.028129373183797046	[81]	[34]	0	hSpCas9	negative selection	10908894
82864460	82864483	4	+	28162770	P31FUJ	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.4541600098091728	[181]	[292]	5	hSpCas9	negative selection	11078251
82857715	82857738	4	-	28162770	P31FUJ	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.016733746377158187	[518]	[616]	0	hSpCas9	negative selection	11078252
82853656	82853679	4	+	28162770	P31FUJ	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.9970653374842158	[274]	[644]	9	hSpCas9	negative selection	11078253
82851547	82851570	4	-	28162770	P31FUJ	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.44121148412390576	[177]	[283]	5	hSpCas9	negative selection	11078254
82851440	82851463	4	+	28162770	P31FUJ	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.7062687969432897	[132]	[254]	7	hSpCas9	negative selection	11078255
82848871	82848894	4	-	28162770	P31FUJ	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.5394635426484305	[187]	[151]	-4	hSpCas9	negative selection	11078256
82848827	82848850	4	+	28162770	P31FUJ	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.321041085927938	[452]	[664]	3	hSpCas9	negative selection	11078257
82874729	82874752	4	+	28162770	P31FUJ	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.5483040301423077	[55]	[44]	-4	hSpCas9	negative selection	11078258
82867284	82867307	4	-	28162770	P31FUJ	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.409679966498458	[155]	[137]	-4	hSpCas9	negative selection	11078259
82866893	82866916	4	+	28162770	P31FUJ	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.1467864588601756	[102]	[133]	1	hSpCas9	negative selection	11078260
82864460	82864483	4	+	28162770	OCIAML5	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	1.1607574694935867	[55]	[225]	8	hSpCas9	negative selection	11247617
82857715	82857738	4	-	28162770	OCIAML5	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.31282603433892864	[350]	[786]	2	hSpCas9	negative selection	11247618
82853656	82853679	4	+	28162770	OCIAML5	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.503649837479649	[210]	[539]	4	hSpCas9	negative selection	11247619
82851547	82851570	4	-	28162770	OCIAML5	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	-0.31149818950129415	[175]	[255]	-2	hSpCas9	negative selection	11247620
82851440	82851463	4	+	28162770	OCIAML5	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-2.0464446160308483	[118]	[51]	-8	hSpCas9	negative selection	11247621
82848871	82848894	4	-	28162770	OCIAML5	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.1332483234080502	[95]	[157]	-1	hSpCas9	negative selection	11247622
82848827	82848850	4	+	28162770	OCIAML5	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.18344614109593138	[267]	[425]	-1	hSpCas9	negative selection	11247623
82874729	82874752	4	+	28162770	OCIAML5	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.2452306304909182	[42]	[91]	2	hSpCas9	negative selection	11247624
82867284	82867307	4	-	28162770	OCIAML5	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.5198701405228077	[111]	[140]	-4	hSpCas9	negative selection	11247625
82866893	82866916	4	+	28162770	OCIAML5	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.018298148719407603	[63]	[116]	0	hSpCas9	negative selection	11247626
82864460	82864483	4	+	28162770	EOL1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	1.470432750309	[236]	[345]	9	hSpCas9	negative selection	11416983
82857715	82857738	4	-	28162770	EOL1	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.25284794887049666	[496]	[311]	2	hSpCas9	negative selection	11416984
82853656	82853679	4	+	28162770	EOL1	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	-0.2148832007505148	[748]	[339]	-2	hSpCas9	negative selection	11416985
82851547	82851570	4	-	28162770	EOL1	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	-0.05817423699762991	[414]	[209]	0	hSpCas9	negative selection	11416986
82851440	82851463	4	+	28162770	EOL1	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.3712765693809288	[355]	[144]	-3	hSpCas9	negative selection	11416987
82848871	82848894	4	-	28162770	EOL1	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.20522010339979507	[371]	[169]	-1	hSpCas9	negative selection	11416988
82848827	82848850	4	+	28162770	EOL1	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.00825847795976642	[384]	[203]	0	hSpCas9	negative selection	11416989
82874729	82874752	4	+	28162770	EOL1	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-1.3317919816892516	[42]	[8]	-7	hSpCas9	negative selection	11416990
82867284	82867307	4	-	28162770	EOL1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.5493362527848792	[130]	[100]	5	hSpCas9	negative selection	11416991
82866893	82866916	4	+	28162770	EOL1	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.2680320098243445	[92]	[58]	2	hSpCas9	negative selection	11416992
82864460	82864483	4	+	28162770	MOLM13	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-1.2101825235680588	[255]	[79]	-6	hSpCas9	negative selection	11586349
82857715	82857738	4	-	28162770	MOLM13	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-1.2342743300789678	[627]	[192]	-6	hSpCas9	negative selection	11586350
82853656	82853679	4	+	28162770	MOLM13	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	-0.6351143106015387	[594]	[276]	-4	hSpCas9	negative selection	11586351
82851547	82851570	4	-	28162770	MOLM13	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	-0.07608470772573864	[346]	[237]	0	hSpCas9	negative selection	11586352
82851440	82851463	4	+	28162770	MOLM13	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-2.0849609340228246	[310]	[52]	-7	hSpCas9	negative selection	11586353
82848871	82848894	4	-	28162770	MOLM13	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.3526628428946021	[301]	[170]	-2	hSpCas9	negative selection	11586354
82848827	82848850	4	+	28162770	MOLM13	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.022097528571590752	[506]	[360]	0	hSpCas9	negative selection	11586355
82874729	82874752	4	+	28162770	MOLM13	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.7104478597139336	[42]	[18]	-4	hSpCas9	negative selection	11586356
82867284	82867307	4	-	28162770	MOLM13	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-2.2810488542877034	[241]	[35]	-8	hSpCas9	negative selection	11586357
82866893	82866916	4	+	28162770	MOLM13	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-1.8665296575259802	[115]	[22]	-7	hSpCas9	negative selection	11586358
82864460	82864483	4	+	28162770	HEL	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.0946759140907299	[192]	[131]	0	hSpCas9	negative selection	11755715
82857715	82857738	4	-	28162770	HEL	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.758571684166975	[522]	[197]	-5	hSpCas9	negative selection	11755716
82853656	82853679	4	+	28162770	HEL	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.31223484293318093	[463]	[368]	2	hSpCas9	negative selection	11755717
82851547	82851570	4	-	28162770	HEL	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	-0.579653589336091	[349]	[149]	-4	hSpCas9	negative selection	11755718
82851440	82851463	4	+	28162770	HEL	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.3001800727923757	[222]	[115]	-2	hSpCas9	negative selection	11755719
82848871	82848894	4	-	28162770	HEL	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	0.18458111635169308	[282]	[205]	1	hSpCas9	negative selection	11755720
82848827	82848850	4	+	28162770	HEL	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.5047704191789967	[462]	[208]	-3	hSpCas9	negative selection	11755721
82874729	82874752	4	+	28162770	HEL	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	1.3927605789920094	[21]	[36]	9	hSpCas9	negative selection	11755722
82867284	82867307	4	-	28162770	HEL	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.7198312473843513	[179]	[69]	-5	hSpCas9	negative selection	11755723
82866893	82866916	4	+	28162770	HEL	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	1.1929359145608365	[83]	[122]	9	hSpCas9	negative selection	11755724
82864460	82864483	4	+	28162770	MV411	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.9711521214511253	[174]	[288]	8	hSpCas9	negative selection	11925081
82857715	82857738	4	-	28162770	MV411	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.7702211157137315	[410]	[202]	-5	hSpCas9	negative selection	11925082
82853656	82853679	4	+	28162770	MV411	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.33785284600499366	[401]	[427]	3	hSpCas9	negative selection	11925083
82851547	82851570	4	-	28162770	MV411	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.271284292737143	[239]	[243]	2	hSpCas9	negative selection	11925084
82851440	82851463	4	+	28162770	MV411	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.5257915873702025	[187]	[109]	-4	hSpCas9	negative selection	11925085
82848871	82848894	4	-	28162770	MV411	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.15671163235333244	[175]	[132]	-1	hSpCas9	negative selection	11925086
82848827	82848850	4	+	28162770	MV411	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.20959419963810277	[308]	[300]	1	hSpCas9	negative selection	11925087
82874729	82874752	4	+	28162770	MV411	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	0.4467463590061822	[26]	[30]	4	hSpCas9	negative selection	11925088
82867284	82867307	4	-	28162770	MV411	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.3375249499383808	[98]	[65]	-3	hSpCas9	negative selection	11925089
82866893	82866916	4	+	28162770	MV411	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.14684138832927118	[45]	[34]	-1	hSpCas9	negative selection	11925090
82864460	82864483	4	+	28162770	MONOMAC1	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.7567929715075205	[126]	[245]	7	hSpCas9	negative selection	12094447
82857715	82857738	4	-	28162770	MONOMAC1	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.08574149407265508	[253]	[308]	0	hSpCas9	negative selection	12094448
82853656	82853679	4	+	28162770	MONOMAC1	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.3262535428713135	[230]	[331]	3	hSpCas9	negative selection	12094449
82851547	82851570	4	-	28162770	MONOMAC1	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.7879609896011996	[144]	[286]	7	hSpCas9	negative selection	12094450
82851440	82851463	4	+	28162770	MONOMAC1	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	0.035623909730721375	[119]	[140]	0	hSpCas9	negative selection	12094451
82848871	82848894	4	-	28162770	MONOMAC1	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.8159466797040476	[171]	[111]	-6	hSpCas9	negative selection	12094452
82848827	82848850	4	+	28162770	MONOMAC1	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.7352185463046119	[217]	[415]	7	hSpCas9	negative selection	12094453
82874729	82874752	4	+	28162770	MONOMAC1	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.6995371875887373	[16]	[11]	-5	hSpCas9	negative selection	12094454
82867284	82867307	4	-	28162770	MONOMAC1	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	0.7463796245740788	[51]	[99]	7	hSpCas9	negative selection	12094455
82866893	82866916	4	+	28162770	MONOMAC1	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	0.5399287471066525	[59]	[99]	5	hSpCas9	negative selection	12094456
82864460	82864483	4	+	28162770	OCIAML2	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	-0.7584321362248971	[46]	[153]	-5	hSpCas9	negative selection	12263813
82857715	82857738	4	-	28162770	OCIAML2	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	-0.6333593252802696	[74]	[267]	-5	hSpCas9	negative selection	12263814
82853656	82853679	4	+	28162770	OCIAML2	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.048243485021222554	[66]	[383]	0	hSpCas9	negative selection	12263815
82851547	82851570	4	-	28162770	OCIAML2	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.43402229817035787	[42]	[321]	4	hSpCas9	negative selection	12263816
82851440	82851463	4	+	28162770	OCIAML2	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.7954695155494268	[30]	[98]	-5	hSpCas9	negative selection	12263817
82848871	82848894	4	-	28162770	OCIAML2	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-0.8974444922973588	[40]	[121]	-6	hSpCas9	negative selection	12263818
82848827	82848850	4	+	28162770	OCIAML2	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	-0.14870173035479883	[73]	[369]	-1	hSpCas9	negative selection	12263819
82874729	82874752	4	+	28162770	OCIAML2	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	-0.5320303699063045	[5]	[22]	-4	hSpCas9	negative selection	12263820
82867284	82867307	4	-	28162770	OCIAML2	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	-0.6341285575250405	[20]	[74]	-5	hSpCas9	negative selection	12263821
82866893	82866916	4	+	28162770	OCIAML2	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.06623957016282578	[16]	[89]	0	hSpCas9	negative selection	12263822
82864460	82864483	4	+	28162770	OCIAML3	viability	GAAGTTGGTCTGATCGGCTGAGG	SEC31A	ENSG00000138674	0.7629269043911124	[56]	[291]	6	hSpCas9	negative selection	12433179
82857715	82857738	4	-	28162770	OCIAML3	viability	GAATTTCTACCCTCATCTGGAGG	SEC31A	ENSG00000138674	0.19148784776970162	[75]	[261]	1	hSpCas9	negative selection	12433180
82853656	82853679	4	+	28162770	OCIAML3	viability	GACATGCTTGAGTCTGCAGGAGG	SEC31A	ENSG00000138674	0.8640712402478848	[96]	[532]	7	hSpCas9	negative selection	12433181
82851547	82851570	4	-	28162770	OCIAML3	viability	TGTGCAACTCACTCAAGCCATGG	SEC31A	ENSG00000138674	0.5372368929540895	[62]	[275]	5	hSpCas9	negative selection	12433182
82851440	82851463	4	+	28162770	OCIAML3	viability	GTTGTCAGGAAGAAAAGCCAAGG	SEC31A	ENSG00000138674	-0.2638590386318322	[69]	[175]	-2	hSpCas9	negative selection	12433183
82848871	82848894	4	-	28162770	OCIAML3	viability	GAGAAACAGCAGCTCCCCAAGGG	SEC31A	ENSG00000138674	-1.3940700698154112	[73]	[84]	-7	hSpCas9	negative selection	12433184
82848827	82848850	4	+	28162770	OCIAML3	viability	GAACTCTTGGCATCTGGTGGTGG	SEC31A	ENSG00000138674	0.4020666564620369	[91]	[366]	4	hSpCas9	negative selection	12433185
82874729	82874752	4	+	28162770	OCIAML3	viability	ATGCAGCTGATATCTTCTGGCGG	SEC31A	ENSG00000138674	1.7279204545631992	[6]	[69]	9	hSpCas9	negative selection	12433186
82867284	82867307	4	-	28162770	OCIAML3	viability	AACTTCCCACCAACACACAGTGG	SEC31A	ENSG00000138674	1.9954007654281853	[26]	[324]	9	hSpCas9	negative selection	12433187
82866893	82866916	4	+	28162770	OCIAML3	viability	GGAATTTGTAACGGAGGAAGGGG	SEC31A	ENSG00000138674	-0.34246887332819886	[20]	[49]	-3	hSpCas9	negative selection	12433188