Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 22941
• Symbol: SHANK2
• Description: SH3 and multiple ankyrin repeat domains 2

DataSource: http://genomecrispr.dkfz.de/#!/results/SHANK2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
71092515	71092538	11	+	26627737	DLD1	viability	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.21669079434560684	[298]	[118,211,13]	2	hSpCas9	negative selection	780819
71094663	71094686	11	+	26627737	DLD1	viability	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.8443730402348757	[135]	[45,11,13]	-7	hSpCas9	negative selection	780820
71109940	71109963	11	-	26627737	DLD1	viability	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.21678905232043233	[233]	[33,106,110]	2	hSpCas9	negative selection	780821
71113347	71113370	11	-	26627737	DLD1	viability	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.953943873654327	[389]	[240,217,246]	8	hSpCas9	negative selection	780822
71118921	71118944	11	-	26627737	DLD1	viability	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	-0.7283328076023994	[422]	[112,68,59]	-6	hSpCas9	negative selection	780823
71147299	71147322	11	-	26627737	DLD1	viability	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.3777860556869137	[1816]	[640,946,648]	4	hSpCas9	negative selection	780825
71092515	71092538	11	+	26627737	GBM cells	viability after 5 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.9490830316692644	[107]	[34,24]	-9	hSpCas9	negative selection	863134
71094663	71094686	11	+	26627737	GBM cells	viability after 5 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.592072477626457	[103]	[38,34]	-7	hSpCas9	negative selection	863135
71109940	71109963	11	-	26627737	GBM cells	viability after 5 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.0003231481793977975	[234]	[111,139]	0	hSpCas9	negative selection	863136
71113347	71113370	11	-	26627737	GBM cells	viability after 5 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.3945454840619836	[321]	[245,207]	6	hSpCas9	negative selection	863137
71118921	71118944	11	-	26627737	GBM cells	viability after 5 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.4975513125039184	[69]	[66,144]	9	hSpCas9	negative selection	863138
71147299	71147322	11	-	26627737	GBM cells	viability after 5 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.05059704482551308	[901]	[520,480]	0	hSpCas9	negative selection	863140
71092515	71092538	11	+	26627737	GBM cells	viability after 13 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-1.1780680260041523	[107]	[26,24]	-8	hSpCas9	negative selection	945449
71094663	71094686	11	+	26627737	GBM cells	viability after 13 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.1187131112613673	[103]	[62,42]	-1	hSpCas9	negative selection	945450
71109940	71109963	11	-	26627737	GBM cells	viability after 13 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.16758497390543253	[234]	[123,104]	-2	hSpCas9	negative selection	945451
71113347	71113370	11	-	26627737	GBM cells	viability after 13 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.44569197350703676	[321]	[275,206]	5	hSpCas9	negative selection	945452
71118921	71118944	11	-	26627737	GBM cells	viability after 13 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.5874770469724102	[69]	[117,110]	9	hSpCas9	negative selection	945453
71147299	71147322	11	-	26627737	GBM cells	viability after 13 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.08252155287428398	[901]	[606,445]	1	hSpCas9	negative selection	945455
71092515	71092538	11	+	26627737	GBM cells	viability after 21 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-1.1197667003843415	[107]	[26,26]	-7	hSpCas9	negative selection	1027764
71094663	71094686	11	+	26627737	GBM cells	viability after 21 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.2955994098759016	[103]	[56,35]	-3	hSpCas9	negative selection	1027765
71109940	71109963	11	-	26627737	GBM cells	viability after 21 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.38304669223300863	[234]	[111,84]	-3	hSpCas9	negative selection	1027766
71113347	71113370	11	-	26627737	GBM cells	viability after 21 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.404461753467007	[321]	[253,210]	4	hSpCas9	negative selection	1027767
71118921	71118944	11	-	26627737	GBM cells	viability after 21 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.2435156451421552	[69]	[88,90]	9	hSpCas9	negative selection	1027768
71147299	71147322	11	-	26627737	GBM cells	viability after 21 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	-0.2324239598881932	[901]	[425,408]	-2	hSpCas9	negative selection	1027770
71092515	71092538	11	+	26627737	RPE1	viability after 9 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.846629248821194	[252]	[79,222]	5	hSpCas9	negative selection	1110079
71094663	71094686	11	+	26627737	RPE1	viability after 9 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.6051955423332367	[234]	[69,165]	4	hSpCas9	negative selection	1110080
71109940	71109963	11	-	26627737	RPE1	viability after 9 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	1.495974115477279	[212]	[198,173]	8	hSpCas9	negative selection	1110081
71113347	71113370	11	-	26627737	RPE1	viability after 9 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.188502720863584	[1173]	[372,477]	1	hSpCas9	negative selection	1110082
71118921	71118944	11	-	26627737	RPE1	viability after 9 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.6582290832680392	[557]	[214,353]	4	hSpCas9	negative selection	1110083
71147299	71147322	11	-	26627737	RPE1	viability after 9 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.9307978860577135	[2771]	[1587,1739]	6	hSpCas9	negative selection	1110085
71092515	71092538	11	+	26627737	RPE1	viability after 12 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.1309024771997318	[252]	[71,76]	0	hSpCas9	negative selection	1192394
71094663	71094686	11	+	26627737	RPE1	viability after 12 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.4563654863342632	[234]	[73,99]	3	hSpCas9	negative selection	1192395
71109940	71109963	11	-	26627737	RPE1	viability after 12 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	1.2552154648500278	[212]	[122,150]	7	hSpCas9	negative selection	1192396
71113347	71113370	11	-	26627737	RPE1	viability after 12 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.27740219714694236	[1173]	[408,353]	1	hSpCas9	negative selection	1192397
71118921	71118944	11	-	26627737	RPE1	viability after 12 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.943202647146723	[557]	[245,332]	6	hSpCas9	negative selection	1192398
71147299	71147322	11	-	26627737	RPE1	viability after 12 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	1.1439481365161432	[2771]	[1569,1725]	6	hSpCas9	negative selection	1192400
71092515	71092538	11	+	26627737	RPE1	viability after 15 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.42779206140599757	[252]	[80,110]	2	hSpCas9	negative selection	1274709
71094663	71094686	11	+	26627737	RPE1	viability after 15 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.024437987019898078	[234]	[16,111]	0	hSpCas9	negative selection	1274710
71109940	71109963	11	-	26627737	RPE1	viability after 15 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	1.2547639005872613	[212]	[127,158]	7	hSpCas9	negative selection	1274711
71113347	71113370	11	-	26627737	RPE1	viability after 15 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.03995850453729155	[1173]	[429,255]	0	hSpCas9	negative selection	1274712
71118921	71118944	11	-	26627737	RPE1	viability after 15 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.8152647876035785	[557]	[94,453]	5	hSpCas9	negative selection	1274713
71147299	71147322	11	-	26627737	RPE1	viability after 15 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	1.0608886194537672	[2771]	[1951,1330]	6	hSpCas9	negative selection	1274715
71092515	71092538	11	+	26627737	RPE1	viability after 18 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.16516832578343843	[252]	[13,110]	-1	hSpCas9	negative selection	1357024
71094663	71094686	11	+	26627737	RPE1	viability after 18 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.10071470153601925	[234]	[38,98]	0	hSpCas9	negative selection	1357025
71109940	71109963	11	-	26627737	RPE1	viability after 18 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	1.4837505322743882	[212]	[182,136]	7	hSpCas9	negative selection	1357026
71113347	71113370	11	-	26627737	RPE1	viability after 18 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.08639602844521499	[1173]	[361,308]	0	hSpCas9	negative selection	1357027
71118921	71118944	11	-	26627737	RPE1	viability after 18 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.24446509544479708	[557]	[116,243]	1	hSpCas9	negative selection	1357028
71147299	71147322	11	-	26627737	RPE1	viability after 18 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	1.2460938519406932	[2771]	[1917,1620]	7	hSpCas9	negative selection	1357030
71092515	71092538	11	+	26627737	HeLa	viability after 8 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.21049216606266952	[144]	[133,92,9]	2	hSpCas9	negative selection	1439339
71094663	71094686	11	+	26627737	HeLa	viability after 8 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.40586814907021185	[101]	[105,24,55]	4	hSpCas9	negative selection	1439340
71109940	71109963	11	-	26627737	HeLa	viability after 8 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.8236645868508461	[189]	[179,54,206]	6	hSpCas9	negative selection	1439341
71113347	71113370	11	-	26627737	HeLa	viability after 8 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.2658265943899242	[699]	[371,232,185]	-3	hSpCas9	negative selection	1439342
71118921	71118944	11	-	26627737	HeLa	viability after 8 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	-0.19742516468677418	[209]	[92,9,134]	-2	hSpCas9	negative selection	1439343
71147299	71147322	11	-	26627737	HeLa	viability after 8 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.26989506125673035	[1582]	[709,849,899]	2	hSpCas9	negative selection	1439345
71092515	71092538	11	+	26627737	HeLa	viability after 12 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.37296756427377864	[144]	[77,56,99]	3	hSpCas9	negative selection	1521654
71094663	71094686	11	+	26627737	HeLa	viability after 12 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.9558779841527927	[101]	[110,35,103]	7	hSpCas9	negative selection	1521655
71109940	71109963	11	-	26627737	HeLa	viability after 12 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.3396181939008325	[189]	[134,24,146]	3	hSpCas9	negative selection	1521656
71113347	71113370	11	-	26627737	HeLa	viability after 12 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.7236129995059996	[699]	[194,166,164]	-6	hSpCas9	negative selection	1521657
71118921	71118944	11	-	26627737	HeLa	viability after 12 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.0541716383670974	[209]	[174,231,127]	7	hSpCas9	negative selection	1521658
71147299	71147322	11	-	26627737	HeLa	viability after 12 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.1284680249303607	[1582]	[958,728,462]	1	hSpCas9	negative selection	1521660
71092515	71092538	11	+	26627737	HeLa	viability after 15 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.13181050457916288	[144]	[53,12,97]	-1	hSpCas9	negative selection	1603969
71094663	71094686	11	+	26627737	HeLa	viability after 15 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.8020332885447836	[101]	[29,63,127]	6	hSpCas9	negative selection	1603970
71109940	71109963	11	-	26627737	HeLa	viability after 15 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.32661917911306115	[189]	[101,54,136]	2	hSpCas9	negative selection	1603971
71113347	71113370	11	-	26627737	HeLa	viability after 15 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.18741513936016263	[699]	[254,253,240]	-1	hSpCas9	negative selection	1603972
71118921	71118944	11	-	26627737	HeLa	viability after 15 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.376886544758718	[209]	[118,427,111]	8	hSpCas9	negative selection	1603973
71147299	71147322	11	-	26627737	HeLa	viability after 15 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.2742245590466452	[1582]	[893,778,653]	2	hSpCas9	negative selection	1603975
71092515	71092538	11	+	26627737	HeLa	viability after 18 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.10512748120776405	[144]	[37,10,97]	-1	hSpCas9	negative selection	1686284
71094663	71094686	11	+	26627737	HeLa	viability after 18 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.7904732154779652	[101]	[18,52,127]	6	hSpCas9	negative selection	1686285
71109940	71109963	11	-	26627737	HeLa	viability after 18 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.406400709036547	[189]	[73,51,136]	3	hSpCas9	negative selection	1686286
71113347	71113370	11	-	26627737	HeLa	viability after 18 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.1748785966821237	[699]	[181,201,240]	-1	hSpCas9	negative selection	1686287
71118921	71118944	11	-	26627737	HeLa	viability after 18 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.391639098031599	[209]	[82,355,111]	8	hSpCas9	negative selection	1686288
71147299	71147322	11	-	26627737	HeLa	viability after 18 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.25788681957175585	[1582]	[573,655,653]	2	hSpCas9	negative selection	1686290
71092515	71092538	11	+	26627737	HCT116	viability after 6 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.1756810440925557	[325]	[73,48]	1	hSpCas9	negative selection	1768599
71094663	71094686	11	+	26627737	HCT116	viability after 6 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.9278437459344141	[327]	[68,3]	-5	hSpCas9	negative selection	1768600
71109940	71109963	11	-	26627737	HCT116	viability after 6 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.8900278023318752	[325]	[103,89]	5	hSpCas9	negative selection	1768601
71113347	71113370	11	-	26627737	HCT116	viability after 6 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-1.9137620598796523	[971]	[46,36]	-8	hSpCas9	negative selection	1768602
71118921	71118944	11	-	26627737	HCT116	viability after 6 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	-2.2852902258498995	[752]	[51,8]	-8	hSpCas9	negative selection	1768603
71147299	71147322	11	-	26627737	HCT116	viability after 6 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.3555447785463839	[2766]	[1077,268]	2	hSpCas9	negative selection	1768605
71092515	71092538	11	+	26627737	HCT116	viability after 8 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	3.0959985284165716	[7]	[34,37,39]	9	hSpCas9	negative selection	1850914
71094663	71094686	11	+	26627737	HCT116	viability after 8 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	2.2646490265630987	[27]	[115,18,87]	9	hSpCas9	negative selection	1850915
71109940	71109963	11	-	26627737	HCT116	viability after 8 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.22951223462998838	[254]	[149,83,125]	-3	hSpCas9	negative selection	1850916
71113347	71113370	11	-	26627737	HCT116	viability after 8 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.31253771154248255	[435]	[299,204,388]	3	hSpCas9	negative selection	1850917
71118921	71118944	11	-	26627737	HCT116	viability after 8 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	3.6072824536178114	[13]	[123,98,59]	9	hSpCas9	negative selection	1850918
71147299	71147322	11	-	26627737	HCT116	viability after 8 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.2705947715462149	[1339]	[849,650,1166]	3	hSpCas9	negative selection	1850920
71092515	71092538	11	+	26627737	HCT116	viability after 9 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	1.1337585319963899	[325]	[209,175]	7	hSpCas9	negative selection	1933229
71094663	71094686	11	+	26627737	HCT116	viability after 9 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.1486169322826255	[327]	[35,112]	-1	hSpCas9	negative selection	1933230
71109940	71109963	11	-	26627737	HCT116	viability after 9 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.4035588891262323	[325]	[170,70]	3	hSpCas9	negative selection	1933231
71113347	71113370	11	-	26627737	HCT116	viability after 9 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-1.2120036572613544	[971]	[63,149]	-7	hSpCas9	negative selection	1933232
71118921	71118944	11	-	26627737	HCT116	viability after 9 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	-2.2685125716793286	[752]	[91,1]	-9	hSpCas9	negative selection	1933233
71147299	71147322	11	-	26627737	HCT116	viability after 9 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.00140345756709781	[2766]	[800,690]	0	hSpCas9	negative selection	1933235
71092515	71092538	11	+	26627737	HCT116	viability after 12 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	4.269261830533965	[7]	[95,43,100]	9	hSpCas9	negative selection	2015544
71094663	71094686	11	+	26627737	HCT116	viability after 12 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	1.0533379161569165	[27]	[45,19,23]	8	hSpCas9	negative selection	2015545
71109940	71109963	11	-	26627737	HCT116	viability after 12 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.38246401185888557	[254]	[116,54,133]	-4	hSpCas9	negative selection	2015546
71113347	71113370	11	-	26627737	HCT116	viability after 12 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.1825027112995139	[435]	[227,225,149]	-2	hSpCas9	negative selection	2015547
71118921	71118944	11	-	26627737	HCT116	viability after 12 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	3.9339766306433517	[13]	[108,43,182]	9	hSpCas9	negative selection	2015548
71147299	71147322	11	-	26627737	HCT116	viability after 12 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.11996307942972662	[1339]	[636,803,866]	1	hSpCas9	negative selection	2015550
71092515	71092538	11	+	26627737	HCT116	viability after 15 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	3.2717606050636316	[7]	[67,23,43]	9	hSpCas9	negative selection	2097859
71094663	71094686	11	+	26627737	HCT116	viability after 15 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	2.148557830202529	[27]	[45,25,137]	9	hSpCas9	negative selection	2097860
71109940	71109963	11	-	26627737	HCT116	viability after 15 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.5259580590092555	[254]	[114,111,79]	-5	hSpCas9	negative selection	2097861
71113347	71113370	11	-	26627737	HCT116	viability after 15 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.06219684731363462	[435]	[371,186,238]	0	hSpCas9	negative selection	2097862
71118921	71118944	11	-	26627737	HCT116	viability after 15 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	3.152262449880557	[13]	[19,101,85]	9	hSpCas9	negative selection	2097863
71147299	71147322	11	-	26627737	HCT116	viability after 15 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.49329396046968776	[1339]	[1295,672,1303]	4	hSpCas9	negative selection	2097865
71092515	71092538	11	+	26627737	HCT116	viability after 18 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	4.040889229786533	[7]	[63,11,120]	9	hSpCas9	negative selection	2180174
71094663	71094686	11	+	26627737	HCT116	viability after 18 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	2.3422144007058714	[27]	[64,0,147]	9	hSpCas9	negative selection	2180175
71109940	71109963	11	-	26627737	HCT116	viability after 18 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-1.059185870760463	[254]	[73,22,83]	-7	hSpCas9	negative selection	2180176
71113347	71113370	11	-	26627737	HCT116	viability after 18 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.12200930772219304	[435]	[238,209,127]	-1	hSpCas9	negative selection	2180177
71118921	71118944	11	-	26627737	HCT116	viability after 18 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	3.1887352038819605	[13]	[35,4,151]	9	hSpCas9	negative selection	2180178
71147299	71147322	11	-	26627737	HCT116	viability after 18 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.6867410841837835	[1339]	[918,1061,1150]	5	hSpCas9	negative selection	2180180
71234002	71234025	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTGAG	SHANK2	ENSG00000162105	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385585
71063032	71063055	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAAAGAGAAAGAGAGAGAAAG	SHANK2	ENSG00000162105	0.039126650339510544	[163,24]	[27,12]	0	dCas9-VP64	positive selection	2385796
70774590	70774613	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTGAGCCACCGTGCCTGG	SHANK2	ENSG00000162105	-0.21542961903399005	[276,86]	[54,10]	-1	dCas9-VP64	positive selection	2388514
70599746	70599769	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCATTGCACTCCAGCCCGG	SHANK2	ENSG00000162105	-1.8772669929253083	[207,39]	[9,2]	-9	dCas9-VP64	positive selection	2411651
70891376	70891399	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCGGAGTAGCTGGGACTACGGG	SHANK2	ENSG00000162105	-1.0701889682907664	[130,53]	[5,12]	-6	dCas9-VP64	positive selection	2415418
70950445	70950468	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGGGGGG	SHANK2	ENSG00000162105	-1.8840232515636643	[4,58]	[0,1]	-9	dCas9-VP64	positive selection	2423293
70613398	70613421	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCTAGGATGG	SHANK2	ENSG00000162105	-0.43622771658323056	[174,104]	[36,6]	-2	dCas9-VP64	positive selection	2433025
70600261	70600284	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACAAAAATTAGCCGGGCGCGG	SHANK2	ENSG00000162105	-0.8999059485131444	[15,116]	[8,5]	-5	dCas9-VP64	positive selection	2433128
70575473	70575496	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCACTCCAGCCAGG	SHANK2	ENSG00000162105	-0.41902599900673143	[34,218]	[4,37]	-2	dCas9-VP64	positive selection	2439585
70904783	70904806	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCATCGTGCCCAG	SHANK2	ENSG00000162105	-2.3680687732448105	[443,16]	[15,1]	-9	dCas9-VP64	positive selection	2440267
71224916	71224939	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGTGTCTACTCCAATTGCCCGG	SHANK2	ENSG00000162105	1.7358426843436823	[107,41]	[63,44]	6	dCas9-VP64	positive selection	2442021
71224895	71224918	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGCAGAAGTTCGATCCCTGG	SHANK2	ENSG00000162105	0.2159840468698037	[76,110]	[9,38]	1	dCas9-VP64	positive selection	2442022
71224943	71224966	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCTTTGTGTGAGGAATAGGG	SHANK2	ENSG00000162105	-1.0564513258775627	[327,36]	[29,5]	-6	dCas9-VP64	positive selection	2442023
71103873	71103896	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGAGAGAGAGAGAAAGAGGGG	SHANK2	ENSG00000162105	-0.15360744684382865	[2,15]	[0,1]	0	dCas9-VP64	positive selection	2442967
71207252	71207275	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCGGG	SHANK2	ENSG00000162105	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444023
71166758	71166781	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCACACCGGG	SHANK2	ENSG00000162105	0.08350517940301261	[638,11]	[141,1]	0	dCas9-VP64	positive selection	2447532
71195156	71195179	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGCGGGAGGATCACAAGG	SHANK2	ENSG00000162105	3.278703021819371	[41,15]	[74,47]	8	dCas9-VP64	positive selection	2449184
71159749	71159772	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGTGGATCACTTGAAG	SHANK2	ENSG00000162105	0.9269503688862448	[9,0]	[1,1]	4	dCas9-VP64	positive selection	2463085
70661981	70662004	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTCAAGGGGGGCTGGCCAGG	SHANK2	ENSG00000162105	0.6548885999307028	[88,36]	[18,23]	3	dCas9-VP64	positive selection	2463319
70661931	70661954	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGGAGTCATACATGGTGGGG	SHANK2	ENSG00000162105	3.2976670721638452	[9,10]	[37,8]	8	dCas9-VP64	positive selection	2463320
70661958	70661981	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGAGGGATGGCTGAGCTGG	SHANK2	ENSG00000162105	-0.025306925266064373	[6,97]	[6,14]	0	dCas9-VP64	positive selection	2463321
70653253	70653276	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACTGCACCCGGCCTGG	SHANK2	ENSG00000162105	1.1797326428655701	[26,26]	[14,10]	4	dCas9-VP64	positive selection	2469518
71207276	71207299	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGTGATTCTCTGGCCTCAG	SHANK2	ENSG00000162105	-1.0637446925394851	[166,163]	[9,24]	-6	dCas9-VP64	positive selection	2471135
71138537	71138560	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAACCACCGCGCCCGG	SHANK2	ENSG00000162105	0.09960352240682058	[3,22]	[3,0]	0	dCas9-VP64	positive selection	2472541
71234002	71234025	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTGAG	SHANK2	ENSG00000162105	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480840
71063032	71063055	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAAAGAGAAAGAGAGAGAAAG	SHANK2	ENSG00000162105	1.133413249914112	[120,136]	[88,94]	7	dCas9-VP64	positive selection	2481051
70774590	70774613	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTGAGCCACCGTGCCTGG	SHANK2	ENSG00000162105	-0.36417141382431395	[64,32]	[9,14]	-4	dCas9-VP64	positive selection	2483769
70599746	70599769	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCATTGCACTCCAGCCCGG	SHANK2	ENSG00000162105	1.3157553862059514	[45,21]	[16,37]	7	dCas9-VP64	positive selection	2506906
70891376	70891399	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCGGAGTAGCTGGGACTACGGG	SHANK2	ENSG00000162105	-0.20642758050950127	[20,72]	[9,15]	-2	dCas9-VP64	positive selection	2510673
70950445	70950468	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGGGGGG	SHANK2	ENSG00000162105	-0.3040415459965904	[20,19]	[5,3]	-3	dCas9-VP64	positive selection	2518548
70613398	70613421	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCTAGGATGG	SHANK2	ENSG00000162105	1.4735482921306557	[116,143]	[227,15]	8	dCas9-VP64	positive selection	2528280
70600261	70600284	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACAAAAATTAGCCGGGCGCGG	SHANK2	ENSG00000162105	-0.9472939245344096	[73,17]	[10,3]	-8	dCas9-VP64	positive selection	2528383
70575473	70575496	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCACTCCAGCCAGG	SHANK2	ENSG00000162105	0.0771162345407751	[282,156]	[110,43]	0	dCas9-VP64	positive selection	2534840
70904783	70904806	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCATCGTGCCCAG	SHANK2	ENSG00000162105	0.42142368151358683	[69,54]	[32,21]	3	dCas9-VP64	positive selection	2535522
71224916	71224939	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGTGTCTACTCCAATTGCCCGG	SHANK2	ENSG00000162105	-0.15293252033767424	[183,257]	[37,89]	-1	dCas9-VP64	positive selection	2537276
71224895	71224918	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGCAGAAGTTCGATCCCTGG	SHANK2	ENSG00000162105	0.9547084618562587	[103,170]	[97,75]	6	dCas9-VP64	positive selection	2537277
71224943	71224966	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCTTTGTGTGAGGAATAGGG	SHANK2	ENSG00000162105	0.9369870049941914	[185,105]	[133,51]	6	dCas9-VP64	positive selection	2537278
71103873	71103896	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGAGAGAGAGAGAAAGAGGGG	SHANK2	ENSG00000162105	6.931899571430513	[13,25]	[4,1590]	9	dCas9-VP64	positive selection	2538222
71207252	71207275	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCGGG	SHANK2	ENSG00000162105	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539278
71166758	71166781	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCACACCGGG	SHANK2	ENSG00000162105	-0.14914508695783546	[201,22]	[49,17]	-1	dCas9-VP64	positive selection	2542787
71195156	71195179	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGCGGGAGGATCACAAGG	SHANK2	ENSG00000162105	0.5394300049106193	[35,34]	[25,7]	4	dCas9-VP64	positive selection	2544439
71159749	71159772	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGTGGATCACTTGAAG	SHANK2	ENSG00000162105	-0.7008385215102662	[31,39]	[9,2]	-6	dCas9-VP64	positive selection	2558340
70661981	70662004	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTCAAGGGGGGCTGGCCAGG	SHANK2	ENSG00000162105	0.4410353034503558	[9,4]	[4,0]	3	dCas9-VP64	positive selection	2558574
70661931	70661954	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGGAGTCATACATGGTGGGG	SHANK2	ENSG00000162105	-0.3973596845501002	[36,56]	[13,7]	-4	dCas9-VP64	positive selection	2558575
70661958	70661981	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGAGGGATGGCTGAGCTGG	SHANK2	ENSG00000162105	1.7920735470459275	[59,36]	[100,11]	8	dCas9-VP64	positive selection	2558576
70653253	70653276	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACTGCACCCGGCCTGG	SHANK2	ENSG00000162105	0.8568341606696415	[42,16]	[22,11]	6	dCas9-VP64	positive selection	2564773
71207276	71207299	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGTGATTCTCTGGCCTCAG	SHANK2	ENSG00000162105	0.3716256793614804	[44,130]	[31,40]	3	dCas9-VP64	positive selection	2566390
71138537	71138560	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAACCACCGCGCCCGG	SHANK2	ENSG00000162105	-0.3804364072538059	[231,140]	[55,37]	-4	dCas9-VP64	positive selection	2567796
71146898	71146921	11	+	27661255	K562	viability	GACAGCAACAGCATGATGTGAGG	SHANK2	ENSG00000162105	-0.04754813148423942	[138,217]	[158,117]	-2	dCas9-KRAB	negative selection	5510855
71147092	71147115	11	+	27661255	K562	viability	GAACCAAAGGGCAGACCACGGGG	SHANK2	ENSG00000162105	0.17423874771070869	[972,1146]	[991,918]	6	dCas9-KRAB	negative selection	5510856
71147210	71147233	11	+	27661255	K562	viability	GGCCCGGATCGTGTCATAGATGG	SHANK2	ENSG00000162105	0.07511847642400937	[1014,1153]	[903,915]	2	dCas9-KRAB	negative selection	5510857
71147267	71147290	11	+	27661255	K562	viability	GGAGTAGTCGGAGAAGCTCTGGG	SHANK2	ENSG00000162105	0.38424400913095846	[199,267]	[273,215]	9	dCas9-KRAB	negative selection	5510858
71147190	71147213	11	-	27661255	K562	viability	GCCACTGCGGAGAAGCCGGGCGG	SHANK2	ENSG00000162105	-0.30118900037423146	[517,462]	[397,250]	-7	dCas9-KRAB	negative selection	5510859
71092515	71092538	11	+	27869803	HPAFII	viability after 27 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.1788174691333706	[155]	[108,41,NaN]	-1	hSpCas9	negative selection	9543819
71094663	71094686	11	+	27869803	HPAFII	viability after 27 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.7215123837651682	[68]	[39,6,NaN]	-5	hSpCas9	negative selection	9543820
71109940	71109963	11	-	27869803	HPAFII	viability after 27 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.08339390339560515	[164]	[104,80,NaN]	0	hSpCas9	negative selection	9543821
71113347	71113370	11	-	27869803	HPAFII	viability after 27 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.09188342959235762	[360]	[204,199,NaN]	0	hSpCas9	negative selection	9543822
71118921	71118944	11	-	27869803	HPAFII	viability after 27 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.8355199013869357	[49]	[41,50,NaN]	6	hSpCas9	negative selection	9543823
71147299	71147322	11	-	27869803	HPAFII	viability after 27 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.11534738144264267	[982]	[675,462,NaN]	0	hSpCas9	negative selection	9543825
71092515	71092538	11	+	27869803	HPAFII	viability after 15 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.8760185664725111	[155]	[107,80,NaN]	-7	hSpCas9	negative selection	9626268
71094663	71094686	11	+	27869803	HPAFII	viability after 15 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.2657241930810057	[68]	[127,64,NaN]	3	hSpCas9	negative selection	9626269
71109940	71109963	11	-	27869803	HPAFII	viability after 15 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	-0.24273582854732034	[164]	[176,132,NaN]	-3	hSpCas9	negative selection	9626270
71113347	71113370	11	-	27869803	HPAFII	viability after 15 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.11015152532317513	[360]	[438,309,NaN]	-1	hSpCas9	negative selection	9626271
71118921	71118944	11	-	27869803	HPAFII	viability after 15 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	1.0823963576650992	[49]	[180,71,NaN]	9	hSpCas9	negative selection	9626272
71147299	71147322	11	-	27869803	HPAFII	viability after 15 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.12198171781442291	[982]	[1005,1238,NaN]	1	hSpCas9	negative selection	9626274
71092515	71092538	11	+	27869803	ASPC1	viability after 36 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.508625290463407	[289]	[146,83,6]	-5	hSpCas9	negative selection	9708717
71094663	71094686	11	+	27869803	ASPC1	viability after 36 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	0.049059232493761984	[153]	[62,96,16]	0	hSpCas9	negative selection	9708718
71109940	71109963	11	-	27869803	ASPC1	viability after 36 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.5421300475904499	[316]	[156,187,140]	5	hSpCas9	negative selection	9708719
71113347	71113370	11	-	27869803	ASPC1	viability after 36 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.9874146582516186	[876]	[373,1164,320]	8	hSpCas9	negative selection	9708720
71118921	71118944	11	-	27869803	ASPC1	viability after 36 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.5750195938779956	[195]	[106,129,74]	6	hSpCas9	negative selection	9708721
71147299	71147322	11	-	27869803	ASPC1	viability after 36 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.30790776497853556	[2417]	[1101,1157,903]	3	hSpCas9	negative selection	9708723
71092515	71092538	11	+	27869803	PATU8988S	viability after 35 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.21798182740389438	[315]	[159,135,NaN]	2	hSpCas9	negative selection	9791166
71094663	71094686	11	+	27869803	PATU8988S	viability after 35 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	1.0831727358941388	[154]	[27,236,NaN]	9	hSpCas9	negative selection	9791167
71109940	71109963	11	-	27869803	PATU8988S	viability after 35 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.42595024353630817	[256]	[163,113,NaN]	5	hSpCas9	negative selection	9791168
71113347	71113370	11	-	27869803	PATU8988S	viability after 35 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.2691688092009534	[678]	[192,260,NaN]	-3	hSpCas9	negative selection	9791169
71118921	71118944	11	-	27869803	PATU8988S	viability after 35 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.44637872228701303	[175]	[134,57,NaN]	5	hSpCas9	negative selection	9791170
71147299	71147322	11	-	27869803	PATU8988S	viability after 35 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.11489559763740731	[2087]	[977,842,NaN]	1	hSpCas9	negative selection	9791172
71092515	71092538	11	+	27869803	PATU8988S	viability after 31 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	0.17769967630303474	[315]	[138,146,NaN]	2	hSpCas9	negative selection	9873615
71094663	71094686	11	+	27869803	PATU8988S	viability after 31 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	1.1270372145337202	[154]	[79,204,NaN]	9	hSpCas9	negative selection	9873616
71109940	71109963	11	-	27869803	PATU8988S	viability after 31 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.2000160382806746	[256]	[100,138,NaN]	2	hSpCas9	negative selection	9873617
71113347	71113370	11	-	27869803	PATU8988S	viability after 31 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.3943318072943966	[678]	[183,233,NaN]	-4	hSpCas9	negative selection	9873618
71118921	71118944	11	-	27869803	PATU8988S	viability after 31 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.9209891518727947	[175]	[120,147,NaN]	8	hSpCas9	negative selection	9873619
71147299	71147322	11	-	27869803	PATU8988S	viability after 31 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.035833451825860285	[2087]	[633,1132,NaN]	0	hSpCas9	negative selection	9873621
71092515	71092538	11	+	27869803	HPAFII	viability after 35 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.3918683859976213	[155]	[86,29,NaN]	-2	hSpCas9	negative selection	9956064
71094663	71094686	11	+	27869803	HPAFII	viability after 35 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.6061006218491425	[68]	[37,5,NaN]	-4	hSpCas9	negative selection	9956065
71109940	71109963	11	-	27869803	HPAFII	viability after 35 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.09162790676689181	[164]	[104,70,NaN]	0	hSpCas9	negative selection	9956066
71113347	71113370	11	-	27869803	HPAFII	viability after 35 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	-0.02080501277094704	[360]	[221,132,NaN]	0	hSpCas9	negative selection	9956067
71118921	71118944	11	-	27869803	HPAFII	viability after 35 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	-0.5103348912514338	[49]	[29,3,NaN]	-3	hSpCas9	negative selection	9956068
71147299	71147322	11	-	27869803	HPAFII	viability after 35 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.5260747289603263	[982]	[749,678,NaN]	3	hSpCas9	negative selection	9956070
71092515	71092538	11	+	27869803	HPAFII	viability after 31 days	GATGGCTGTGTGATACAGCGGGG	SHANK2	ENSG00000162105	-0.6785620912817965	[155]	[47,61,NaN]	-4	hSpCas9	negative selection	10038513
71094663	71094686	11	+	27869803	HPAFII	viability after 31 days	CTGAGCGGCTAAGGTCAGGGGGG	SHANK2	ENSG00000162105	-0.8393341956875644	[68]	[35,5,NaN]	-5	hSpCas9	negative selection	10038514
71109940	71109963	11	-	27869803	HPAFII	viability after 31 days	TTCCACGACCCGGAGACCGGAGG	SHANK2	ENSG00000162105	0.3554443454808528	[164]	[128,106,NaN]	2	hSpCas9	negative selection	10038515
71113347	71113370	11	-	27869803	HPAFII	viability after 31 days	GCCAGTTTCGATACAAGAAGCGG	SHANK2	ENSG00000162105	0.07695927056053542	[360]	[273,147,NaN]	0	hSpCas9	negative selection	10038516
71118921	71118944	11	-	27869803	HPAFII	viability after 31 days	GAACTACGGCCTGTTCCAGCCGG	SHANK2	ENSG00000162105	0.5781473858714374	[49]	[72,7,NaN]	4	hSpCas9	negative selection	10038517
71147299	71147322	11	-	27869803	HPAFII	viability after 31 days	GCGCAGCCCAACATCCAGCGAGG	SHANK2	ENSG00000162105	0.20968775033949072	[982]	[670,601,NaN]	1	hSpCas9	negative selection	10038519
70492349	70492372	11	-	28162770	P31FUJ	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.21998153233466278	[1225]	[1677]	2	hSpCas9	negative selection	10233754
70487316	70487339	11	-	28162770	P31FUJ	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.35122134733716237	[1536]	[2303]	4	hSpCas9	negative selection	10233755
70487159	70487182	11	-	28162770	P31FUJ	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.5241684539249047	[486]	[822]	6	hSpCas9	negative selection	10233756
70486712	70486735	11	-	28162770	P31FUJ	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.2766999788679576	[1595]	[2271]	3	hSpCas9	negative selection	10233757
70486581	70486604	11	-	28162770	P31FUJ	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.9235398247550087	[82]	[184]	9	hSpCas9	negative selection	10233758
70486223	70486246	11	-	28162770	P31FUJ	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.6841697616696298	[1349]	[2548]	7	hSpCas9	negative selection	10233759
70659872	70659895	11	-	28162770	P31FUJ	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.40994069608926553	[1202]	[1063]	-4	hSpCas9	negative selection	10233760
70502844	70502867	11	-	28162770	P31FUJ	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.16490194610319442	[941]	[1240]	1	hSpCas9	negative selection	10233761
70492374	70492397	11	-	28162770	P31FUJ	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.35258845925424076	[1122]	[1684]	4	hSpCas9	negative selection	10233762
70487576	70487599	11	+	28162770	P31FUJ	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-1.2585982052917162	[789]	[387]	-7	hSpCas9	negative selection	10233763
70492349	70492372	11	-	28162770	TF1	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10403120
70487316	70487339	11	-	28162770	TF1	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	NaN	[NaN]	[410]	1	hSpCas9	negative selection	10403121
70487159	70487182	11	-	28162770	TF1	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10403122
70486712	70486735	11	-	28162770	TF1	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10403123
70486581	70486604	11	-	28162770	TF1	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10403124
70486223	70486246	11	-	28162770	TF1	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	NaN	[NaN]	[489]	1	hSpCas9	negative selection	10403125
70659872	70659895	11	-	28162770	TF1	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10403126
70502844	70502867	11	-	28162770	TF1	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10403127
70492374	70492397	11	-	28162770	TF1	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	NaN	[NaN]	[300]	1	hSpCas9	negative selection	10403128
70487576	70487599	11	+	28162770	TF1	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10403129
70492349	70492372	11	-	28162770	SKM1	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.23414138001552837	[62]	[130]	2	hSpCas9	negative selection	10572486
70487316	70487339	11	-	28162770	SKM1	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.18519380338219826	[99]	[200]	1	hSpCas9	negative selection	10572487
70487159	70487182	11	-	28162770	SKM1	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.3563355432365069	[37]	[85]	3	hSpCas9	negative selection	10572488
70486712	70486735	11	-	28162770	SKM1	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.4410327078117884	[114]	[275]	4	hSpCas9	negative selection	10572489
70486581	70486604	11	-	28162770	SKM1	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.7629608026991508	[3]	[11]	7	hSpCas9	negative selection	10572490
70486223	70486246	11	-	28162770	SKM1	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.5981067908042603	[70]	[189]	6	hSpCas9	negative selection	10572491
70659872	70659895	11	-	28162770	SKM1	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.1187192301120879	[77]	[126]	-1	hSpCas9	negative selection	10572492
70502844	70502867	11	-	28162770	SKM1	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.45697425168081	[74]	[181]	4	hSpCas9	negative selection	10572493
70492374	70492397	11	-	28162770	SKM1	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.7884958948062882	[55]	[170]	7	hSpCas9	negative selection	10572494
70487576	70487599	11	+	28162770	SKM1	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.8220016980220054	[47]	[47]	-6	hSpCas9	negative selection	10572495
70492349	70492372	11	-	28162770	SKM1	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.23414138001552837	[62]	[130]	2	hSpCas9	negative selection	10741852
70487316	70487339	11	-	28162770	SKM1	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.18519380338219826	[99]	[200]	1	hSpCas9	negative selection	10741853
70487159	70487182	11	-	28162770	SKM1	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.3563355432365069	[37]	[85]	3	hSpCas9	negative selection	10741854
70486712	70486735	11	-	28162770	SKM1	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.4410327078117884	[114]	[275]	4	hSpCas9	negative selection	10741855
70486581	70486604	11	-	28162770	SKM1	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.7629608026991508	[3]	[11]	7	hSpCas9	negative selection	10741856
70486223	70486246	11	-	28162770	SKM1	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.5981067908042603	[70]	[189]	6	hSpCas9	negative selection	10741857
70659872	70659895	11	-	28162770	SKM1	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.1187192301120879	[77]	[126]	-1	hSpCas9	negative selection	10741858
70502844	70502867	11	-	28162770	SKM1	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.45697425168081	[74]	[181]	4	hSpCas9	negative selection	10741859
70492374	70492397	11	-	28162770	SKM1	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.7884958948062882	[55]	[170]	7	hSpCas9	negative selection	10741860
70487576	70487599	11	+	28162770	SKM1	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.8220016980220054	[47]	[47]	-6	hSpCas9	negative selection	10741861
70492349	70492372	11	-	28162770	PL21	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.2831953542168786	[269]	[142]	2	hSpCas9	negative selection	10911218
70487316	70487339	11	-	28162770	PL21	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.8021291267711287	[364]	[276]	7	hSpCas9	negative selection	10911219
70487159	70487182	11	-	28162770	PL21	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.18024005705161514	[145]	[71]	1	hSpCas9	negative selection	10911220
70486712	70486735	11	-	28162770	PL21	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	-0.27075111952304115	[315]	[113]	-2	hSpCas9	negative selection	10911221
70486581	70486604	11	-	28162770	PL21	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-1.2592920041479774	[10]	[1]	-7	hSpCas9	negative selection	10911222
70486223	70486246	11	-	28162770	PL21	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	-0.19413932462272626	[275]	[104]	-1	hSpCas9	negative selection	10911223
70659872	70659895	11	-	28162770	PL21	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.4329901686923459	[334]	[107]	-3	hSpCas9	negative selection	10911224
70502844	70502867	11	-	28162770	PL21	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	-2.024491279043127	[214]	[22]	-8	hSpCas9	negative selection	10911225
70492374	70492397	11	-	28162770	PL21	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.8240962468263399	[291]	[224]	7	hSpCas9	negative selection	10911226
70487576	70487599	11	+	28162770	PL21	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	0.9552877426205985	[204]	[172]	7	hSpCas9	negative selection	10911227
70492349	70492372	11	-	28162770	P31FUJ	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.21998153233466278	[1225]	[1677]	2	hSpCas9	negative selection	11080584
70487316	70487339	11	-	28162770	P31FUJ	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.35122134733716237	[1536]	[2303]	4	hSpCas9	negative selection	11080585
70487159	70487182	11	-	28162770	P31FUJ	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.5241684539249047	[486]	[822]	6	hSpCas9	negative selection	11080586
70486712	70486735	11	-	28162770	P31FUJ	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.2766999788679576	[1595]	[2271]	3	hSpCas9	negative selection	11080587
70486581	70486604	11	-	28162770	P31FUJ	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.9235398247550087	[82]	[184]	9	hSpCas9	negative selection	11080588
70486223	70486246	11	-	28162770	P31FUJ	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.6841697616696298	[1349]	[2548]	7	hSpCas9	negative selection	11080589
70659872	70659895	11	-	28162770	P31FUJ	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.40994069608926553	[1202]	[1063]	-4	hSpCas9	negative selection	11080590
70502844	70502867	11	-	28162770	P31FUJ	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.16490194610319442	[941]	[1240]	1	hSpCas9	negative selection	11080591
70492374	70492397	11	-	28162770	P31FUJ	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.35258845925424076	[1122]	[1684]	4	hSpCas9	negative selection	11080592
70487576	70487599	11	+	28162770	P31FUJ	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-1.2585982052917162	[789]	[387]	-7	hSpCas9	negative selection	11080593
70492349	70492372	11	-	28162770	OCIAML5	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	-0.2889871880412907	[154]	[228]	-2	hSpCas9	negative selection	11249950
70487316	70487339	11	-	28162770	OCIAML5	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.6504337696651862	[167]	[475]	5	hSpCas9	negative selection	11249951
70487159	70487182	11	-	28162770	OCIAML5	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	2.589368618479454	[21]	[238]	9	hSpCas9	negative selection	11249952
70486712	70486735	11	-	28162770	OCIAML5	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.15260991634547622	[153]	[308]	1	hSpCas9	negative selection	11249953
70486581	70486604	11	-	28162770	OCIAML5	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-1.5301384759766345	[7]	[4]	-7	hSpCas9	negative selection	11249954
70486223	70486246	11	-	28162770	OCIAML5	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.3357686284360826	[168]	[384]	3	hSpCas9	negative selection	11249955
70659872	70659895	11	-	28162770	OCIAML5	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-1.0711838601675838	[219]	[188]	-6	hSpCas9	negative selection	11249956
70502844	70502867	11	-	28162770	OCIAML5	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	-0.20275365873278317	[189]	[297]	-1	hSpCas9	negative selection	11249957
70492374	70492397	11	-	28162770	OCIAML5	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.07393284769222633	[129]	[246]	0	hSpCas9	negative selection	11249958
70487576	70487599	11	+	28162770	OCIAML5	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-2.3610802183518547	[73]	[25]	-8	hSpCas9	negative selection	11249959
70492349	70492372	11	-	28162770	EOL1	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.5434576042150283	[391]	[300]	5	hSpCas9	negative selection	11419316
70487316	70487339	11	-	28162770	EOL1	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	-0.2066967617077181	[597]	[272]	-1	hSpCas9	negative selection	11419317
70487159	70487182	11	-	28162770	EOL1	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.4720355668730277	[155]	[113]	4	hSpCas9	negative selection	11419318
70486712	70486735	11	-	28162770	EOL1	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.14156085624820847	[498]	[289]	1	hSpCas9	negative selection	11419319
70486581	70486604	11	-	28162770	EOL1	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-0.49048972770830934	[23]	[8]	-4	hSpCas9	negative selection	11419320
70486223	70486246	11	-	28162770	EOL1	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.6573255687733071	[413]	[343]	6	hSpCas9	negative selection	11419321
70659872	70659895	11	-	28162770	EOL1	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	0.551993603613204	[434]	[335]	5	hSpCas9	negative selection	11419322
70502844	70502867	11	-	28162770	EOL1	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.33743038614570425	[334]	[222]	3	hSpCas9	negative selection	11419323
70492374	70492397	11	-	28162770	EOL1	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.47484510045985207	[350]	[256]	4	hSpCas9	negative selection	11419324
70487576	70487599	11	+	28162770	EOL1	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.12840110837842456	[221]	[106]	-1	hSpCas9	negative selection	11419325
70492349	70492372	11	-	28162770	MOLM13	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.4487805585968744	[379]	[374]	3	hSpCas9	negative selection	11588682
70487316	70487339	11	-	28162770	MOLM13	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	-0.4358129364328921	[564]	[301]	-3	hSpCas9	negative selection	11588683
70487159	70487182	11	-	28162770	MOLM13	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	-0.6145727786473941	[179]	[84]	-4	hSpCas9	negative selection	11588684
70486712	70486735	11	-	28162770	MOLM13	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.33882680849046665	[408]	[373]	2	hSpCas9	negative selection	11588685
70486581	70486604	11	-	28162770	MOLM13	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-2.854038713342784	[9]	[0]	-8	hSpCas9	negative selection	11588686
70486223	70486246	11	-	28162770	MOLM13	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	-0.056637265314603336	[373]	[259]	0	hSpCas9	negative selection	11588687
70659872	70659895	11	-	28162770	MOLM13	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-1.674489293012071	[414]	[93]	-7	hSpCas9	negative selection	11588688
70502844	70502867	11	-	28162770	MOLM13	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	-0.052017235588220086	[270]	[188]	0	hSpCas9	negative selection	11588689
70492374	70492397	11	-	28162770	MOLM13	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.296367595167937	[338]	[300]	2	hSpCas9	negative selection	11588690
70487576	70487599	11	+	28162770	MOLM13	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-1.1307480560736538	[211]	[69]	-5	hSpCas9	negative selection	11588691
70492349	70492372	11	-	28162770	HEL	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	1.0505736451208472	[250]	[332]	8	hSpCas9	negative selection	11758048
70487316	70487339	11	-	28162770	HEL	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	-0.14688571143841256	[464]	[268]	-1	hSpCas9	negative selection	11758049
70487159	70487182	11	-	28162770	HEL	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.611932785219182	[141]	[138]	5	hSpCas9	negative selection	11758050
70486712	70486735	11	-	28162770	HEL	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.356117605848947	[443]	[363]	3	hSpCas9	negative selection	11758051
70486581	70486604	11	-	28162770	HEL	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-0.942223668720799	[11]	[3]	-5	hSpCas9	negative selection	11758052
70486223	70486246	11	-	28162770	HEL	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	1.3916770678326391	[215]	[362]	9	hSpCas9	negative selection	11758053
70659872	70659895	11	-	28162770	HEL	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	0.08381419218072395	[301]	[204]	0	hSpCas9	negative selection	11758054
70502844	70502867	11	-	28162770	HEL	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.07190666011408893	[253]	[170]	0	hSpCas9	negative selection	11758055
70492374	70492397	11	-	28162770	HEL	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.16052334737118357	[358]	[256]	1	hSpCas9	negative selection	11758056
70487576	70487599	11	+	28162770	HEL	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.9225948619718667	[218]	[73]	-5	hSpCas9	negative selection	11758057
70492349	70492372	11	-	28162770	MV411	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.26270430743608575	[281]	[284]	2	hSpCas9	negative selection	11927414
70487316	70487339	11	-	28162770	MV411	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	-0.2463119245101093	[451]	[320]	-2	hSpCas9	negative selection	11927415
70487159	70487182	11	-	28162770	MV411	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	-0.18042398885365185	[112]	[83]	-1	hSpCas9	negative selection	11927416
70486712	70486735	11	-	28162770	MV411	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	-0.2946391370852044	[347]	[238]	-2	hSpCas9	negative selection	11927417
70486581	70486604	11	-	28162770	MV411	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	-0.3899923698325165	[13]	[8]	-3	hSpCas9	negative selection	11927418
70486223	70486246	11	-	28162770	MV411	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.2144224935548124	[220]	[215]	1	hSpCas9	negative selection	11927419
70659872	70659895	11	-	28162770	MV411	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-1.4335716374094156	[294]	[91]	-7	hSpCas9	negative selection	11927420
70502844	70502867	11	-	28162770	MV411	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	-0.21711390353764604	[246]	[178]	-2	hSpCas9	negative selection	11927421
70492374	70492397	11	-	28162770	MV411	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.12764303824806084	[250]	[230]	1	hSpCas9	negative selection	11927422
70487576	70487599	11	+	28162770	MV411	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.9749548705536726	[188]	[80]	-6	hSpCas9	negative selection	11927423
70492349	70492372	11	-	28162770	MONOMAC1	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	-0.05423624666052951	[172]	[190]	0	hSpCas9	negative selection	12096780
70487316	70487339	11	-	28162770	MONOMAC1	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	1.141352494526978	[243]	[616]	8	hSpCas9	negative selection	12096781
70487159	70487182	11	-	28162770	MONOMAC1	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	0.4948408575781144	[64]	[104]	5	hSpCas9	negative selection	12096782
70486712	70486735	11	-	28162770	MONOMAC1	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.040826983039334075	[211]	[249]	0	hSpCas9	negative selection	12096783
70486581	70486604	11	-	28162770	MONOMAC1	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.8029631529404462	[7]	[15]	7	hSpCas9	negative selection	12096784
70486223	70486246	11	-	28162770	MONOMAC1	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.6631054893574857	[183]	[333]	6	hSpCas9	negative selection	12096785
70659872	70659895	11	-	28162770	MONOMAC1	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.33317353504558256	[210]	[191]	-3	hSpCas9	negative selection	12096786
70502844	70502867	11	-	28162770	MONOMAC1	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.5958052452991587	[156]	[271]	6	hSpCas9	negative selection	12096787
70492374	70492397	11	-	28162770	MONOMAC1	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.2796727630095791	[165]	[230]	3	hSpCas9	negative selection	12096788
70487576	70487599	11	+	28162770	MONOMAC1	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.8554204172500792	[130]	[82]	-6	hSpCas9	negative selection	12096789
70492349	70492372	11	-	28162770	OCIAML2	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	-0.09125145817089919	[63]	[332]	0	hSpCas9	negative selection	12266146
70487316	70487339	11	-	28162770	OCIAML2	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	0.03616106132188279	[78]	[448]	0	hSpCas9	negative selection	12266147
70487159	70487182	11	-	28162770	OCIAML2	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	1.0912490623659536	[20]	[247]	9	hSpCas9	negative selection	12266148
70486712	70486735	11	-	28162770	OCIAML2	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	-0.08865434668485994	[79]	[416]	0	hSpCas9	negative selection	12266149
70486581	70486604	11	-	28162770	OCIAML2	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	0.22980989289893072	[3]	[25]	2	hSpCas9	negative selection	12266150
70486223	70486246	11	-	28162770	OCIAML2	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.7528584526155597	[46]	[438]	7	hSpCas9	negative selection	12266151
70659872	70659895	11	-	28162770	OCIAML2	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	0.28301451007067524	[42]	[289]	2	hSpCas9	negative selection	12266152
70502844	70502867	11	-	28162770	OCIAML2	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	-0.6718880334892651	[47]	[166]	-5	hSpCas9	negative selection	12266153
70492374	70492397	11	-	28162770	OCIAML2	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	0.3136414837024015	[53]	[371]	3	hSpCas9	negative selection	12266154
70487576	70487599	11	+	28162770	OCIAML2	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.7837877105017915	[40]	[131]	-5	hSpCas9	negative selection	12266155
70492349	70492372	11	-	28162770	OCIAML3	viability	CAGCAGCCGGTGCTTCCCGGCGG	SHANK2	ENSG00000162105	0.465773588001254	[64]	[270]	4	hSpCas9	negative selection	12435512
70487316	70487339	11	-	28162770	OCIAML3	viability	AGAAAACCCATACTCAGAGGTGG	SHANK2	ENSG00000162105	1.2379672485064446	[82]	[590]	8	hSpCas9	negative selection	12435513
70487159	70487182	11	-	28162770	OCIAML3	viability	GAGCCGTCCACCAGCAGCAGCGG	SHANK2	ENSG00000162105	-1.797541034409295	[37]	[32]	-8	hSpCas9	negative selection	12435514
70486712	70486735	11	-	28162770	OCIAML3	viability	GCAGTGCCCTCCGCGAGCAGCGG	SHANK2	ENSG00000162105	0.11310196968278363	[82]	[270]	1	hSpCas9	negative selection	12435515
70486581	70486604	11	-	28162770	OCIAML3	viability	TCAACAGGGACCCAAAGGGGAGG	SHANK2	ENSG00000162105	2.7458423625604613	[3]	[80]	9	hSpCas9	negative selection	12435516
70486223	70486246	11	-	28162770	OCIAML3	viability	GAAGGTGTTTCCGAAACCGAAGG	SHANK2	ENSG00000162105	0.5380958956831821	[72]	[319]	5	hSpCas9	negative selection	12435517
70659872	70659895	11	-	28162770	OCIAML3	viability	GGAGTCCGTGGATGAAGGTGGGG	SHANK2	ENSG00000162105	-0.8074112784333565	[79]	[137]	-6	hSpCas9	negative selection	12435518
70502844	70502867	11	-	28162770	OCIAML3	viability	GAATCACCTGGTCCTTAAGGTGG	SHANK2	ENSG00000162105	0.2500420817141239	[60]	[218]	2	hSpCas9	negative selection	12435519
70492374	70492397	11	-	28162770	OCIAML3	viability	GGGTGGCGACCATCAAGCAGCGG	SHANK2	ENSG00000162105	-0.2638590386318322	[69]	[175]	-2	hSpCas9	negative selection	12435520
70487576	70487599	11	+	28162770	OCIAML3	viability	TAAGTGGTTGGGGAAGGTGGTGG	SHANK2	ENSG00000162105	-0.8965704103445944	[73]	[119]	-6	hSpCas9	negative selection	12435521