Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 283652
• Symbol: SLC24A5
• Description: solute carrier family 24 member 5

DataSource: http://genomecrispr.dkfz.de/#!/results/SLC24A5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48121106	48121129	15	-	26472758	Jiyoye	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.6813503449448675	[171]	[207]	5	hSpCas9	negative selection	148435
48121058	48121081	15	+	26472758	Jiyoye	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	1.3331748000620967	[29]	[56]	7	hSpCas9	negative selection	148437
48134258	48134281	15	-	26472758	Jiyoye	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.4071753815058735	[106]	[106]	3	hSpCas9	negative selection	148438
48121883	48121906	15	+	26472758	Jiyoye	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.7697454608905817	[69]	[89]	5	hSpCas9	negative selection	148439
48134283	48134306	15	+	26472758	Jiyoye	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	-0.7341804677396682	[74]	[33]	-5	hSpCas9	negative selection	148440
48134499	48134522	15	-	26472758	Jiyoye	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.6136262589732997	[77]	[89]	4	hSpCas9	negative selection	148441
48121106	48121129	15	-	26472758	KBM7	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.47096487305158163	[893,517]	[377,513]	5	hSpCas9	negative selection	339553
48121058	48121081	15	+	26472758	KBM7	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.4307317166876552	[201,156]	[124,101]	4	hSpCas9	negative selection	339555
48134258	48134281	15	-	26472758	KBM7	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.20676243028468638	[518,453]	[414,127]	2	hSpCas9	negative selection	339556
48121883	48121906	15	+	26472758	KBM7	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.4220763685865282	[518,271]	[177,299]	4	hSpCas9	negative selection	339557
48134283	48134306	15	+	26472758	KBM7	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.4069703214748199	[325,193]	[230,93]	4	hSpCas9	negative selection	339558
48134499	48134522	15	-	26472758	KBM7	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.25431253153609124	[532,357]	[282,212]	2	hSpCas9	negative selection	339559
48121106	48121129	15	-	26472758	Raji	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	1.076087404884061	[232]	[113]	8	hSpCas9	negative selection	530671
48121058	48121081	15	+	26472758	Raji	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.06473919796510574	[102]	[24]	0	hSpCas9	negative selection	530673
48134258	48134281	15	-	26472758	Raji	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.3000286133159954	[286]	[81]	3	hSpCas9	negative selection	530674
48121883	48121906	15	+	26472758	Raji	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.3273492193155074	[169]	[98]	9	hSpCas9	negative selection	530675
48134283	48134306	15	+	26472758	Raji	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.36487975766596326	[86]	[25]	3	hSpCas9	negative selection	530676
48134499	48134522	15	-	26472758	Raji	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	1.0535166633948636	[190]	[91]	8	hSpCas9	negative selection	530677
48121106	48121129	15	-	26472758	K562	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.8727272583131901	[611]	[945]	7	hSpCas9	negative selection	721789
48121058	48121081	15	+	26472758	K562	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	2.177991365927471	[99]	[381]	9	hSpCas9	negative selection	721791
48134258	48134281	15	-	26472758	K562	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.49531257062802864	[357]	[425]	4	hSpCas9	negative selection	721792
48121883	48121906	15	+	26472758	K562	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.3101701240111905	[281]	[191]	-2	hSpCas9	negative selection	721793
48134283	48134306	15	+	26472758	K562	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.5031529960666152	[167]	[200]	4	hSpCas9	negative selection	721794
48134499	48134522	15	-	26472758	K562	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.9416224929572806	[308]	[500]	7	hSpCas9	negative selection	721795
48121059	48121082	15	+	26627737	DLD1	viability	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.7253703760238506	[489]	[262,351,162]	7	hSpCas9	negative selection	790851
48121098	48121121	15	-	26627737	DLD1	viability	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.3053772260586458	[426]	[258,156,89]	3	hSpCas9	negative selection	790852
48121883	48121906	15	+	26627737	DLD1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.2796187348654398	[627]	[224,196,283]	3	hSpCas9	negative selection	790853
48121913	48121936	15	+	26627737	DLD1	viability	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.2024969444780279	[728]	[291,141,162]	-2	hSpCas9	negative selection	790854
48121059	48121082	15	+	26627737	GBM cells	viability after 5 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.22601601611098515	[333]	[195,222]	3	hSpCas9	negative selection	873166
48121098	48121121	15	-	26627737	GBM cells	viability after 5 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-0.2779638871983937	[181]	[79,80]	-4	hSpCas9	negative selection	873167
48121883	48121906	15	+	26627737	GBM cells	viability after 5 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.03825928765887565	[336]	[188,162]	0	hSpCas9	negative selection	873168
48121913	48121936	15	+	26627737	GBM cells	viability after 5 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.27676081485611276	[333]	[225,207]	4	hSpCas9	negative selection	873169
48121059	48121082	15	+	26627737	GBM cells	viability after 13 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.2559849320872099	[333]	[270,171]	3	hSpCas9	negative selection	955481
48121098	48121121	15	-	26627737	GBM cells	viability after 13 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.45966377570373895	[181]	[78,181]	6	hSpCas9	negative selection	955482
48121883	48121906	15	+	26627737	GBM cells	viability after 13 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.2263141155923664	[336]	[136,171]	-3	hSpCas9	negative selection	955483
48121913	48121936	15	+	26627737	GBM cells	viability after 13 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.2800478261273787	[333]	[165,263]	3	hSpCas9	negative selection	955484
48121059	48121082	15	+	26627737	GBM cells	viability after 21 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.2097694507776586	[333]	[170,143]	-2	hSpCas9	negative selection	1037796
48121098	48121121	15	-	26627737	GBM cells	viability after 21 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.7819238862668236	[181]	[204,137]	7	hSpCas9	negative selection	1037797
48121883	48121906	15	+	26627737	GBM cells	viability after 21 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.8361096453627381	[336]	[112,92]	-6	hSpCas9	negative selection	1037798
48121913	48121936	15	+	26627737	GBM cells	viability after 21 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.6419234200101305	[333]	[314,253]	6	hSpCas9	negative selection	1037799
48121059	48121082	15	+	26627737	RPE1	viability after 9 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	1.9719676078601218	[552]	[552,841]	8	hSpCas9	negative selection	1120111
48121098	48121121	15	-	26627737	RPE1	viability after 9 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	1.192206315079072	[363]	[269,247]	7	hSpCas9	negative selection	1120112
48121883	48121906	15	+	26627737	RPE1	viability after 9 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-1.9686013669933593	[1324]	[98,114]	-8	hSpCas9	negative selection	1120113
48121913	48121936	15	+	26627737	RPE1	viability after 9 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	1.4319130867177035	[603]	[538,472]	7	hSpCas9	negative selection	1120114
48121059	48121082	15	+	26627737	RPE1	viability after 12 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	2.1506732771549415	[552]	[751,561]	9	hSpCas9	negative selection	1202426
48121098	48121121	15	-	26627737	RPE1	viability after 12 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	1.2667618691617295	[363]	[228,241]	7	hSpCas9	negative selection	1202427
48121883	48121906	15	+	26627737	RPE1	viability after 12 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.42846340231786145	[1324]	[162,371]	-3	hSpCas9	negative selection	1202428
48121913	48121936	15	+	26627737	RPE1	viability after 12 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	1.9232212607656363	[603]	[613,616]	8	hSpCas9	negative selection	1202429
48121059	48121082	15	+	26627737	RPE1	viability after 15 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	1.977924222974506	[552]	[687,546]	8	hSpCas9	negative selection	1284741
48121098	48121121	15	-	26627737	RPE1	viability after 15 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.9300789009290489	[363]	[100,287]	5	hSpCas9	negative selection	1284742
48121883	48121906	15	+	26627737	RPE1	viability after 15 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.9981672976112578	[1324]	[66,303]	-6	hSpCas9	negative selection	1284743
48121913	48121936	15	+	26627737	RPE1	viability after 15 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	1.5799997448317837	[603]	[689,337]	8	hSpCas9	negative selection	1284744
48121059	48121082	15	+	26627737	RPE1	viability after 18 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	2.072521719303197	[552]	[575,682]	8	hSpCas9	negative selection	1367056
48121098	48121121	15	-	26627737	RPE1	viability after 18 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	1.308289071292793	[363]	[221,265]	7	hSpCas9	negative selection	1367057
48121883	48121906	15	+	26627737	RPE1	viability after 18 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-1.0600236840409916	[1324]	[156,186]	-6	hSpCas9	negative selection	1367058
48121913	48121936	15	+	26627737	RPE1	viability after 18 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	2.2091128247632956	[603]	[1152,326]	9	hSpCas9	negative selection	1367059
48121059	48121082	15	+	26627737	HeLa	viability after 8 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.6895454831965266	[531]	[336,341,428]	6	hSpCas9	negative selection	1449371
48121098	48121121	15	-	26627737	HeLa	viability after 8 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.17973422168292658	[418]	[273,162,197]	1	hSpCas9	negative selection	1449372
48121883	48121906	15	+	26627737	HeLa	viability after 8 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.10444302883086509	[470]	[303,133,160]	-1	hSpCas9	negative selection	1449373
48121913	48121936	15	+	26627737	HeLa	viability after 8 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.71831009039784	[1002]	[208,450,132]	-6	hSpCas9	negative selection	1449374
48121059	48121082	15	+	26627737	HeLa	viability after 12 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.6939042645924276	[531]	[51,166,182]	-6	hSpCas9	negative selection	1531686
48121098	48121121	15	-	26627737	HeLa	viability after 12 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-0.2960151960796124	[418]	[134,130,157]	-3	hSpCas9	negative selection	1531687
48121883	48121906	15	+	26627737	HeLa	viability after 12 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.6868558462059104	[470]	[326,354,253]	5	hSpCas9	negative selection	1531688
48121913	48121936	15	+	26627737	HeLa	viability after 12 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.4018643699608462	[1002]	[249,382,298]	-4	hSpCas9	negative selection	1531689
48121059	48121082	15	+	26627737	HeLa	viability after 15 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.3415304580592796	[531]	[183,164,162]	-3	hSpCas9	negative selection	1614001
48121098	48121121	15	-	26627737	HeLa	viability after 15 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-1.0609933606702298	[418]	[24,90,133]	-7	hSpCas9	negative selection	1614002
48121883	48121906	15	+	26627737	HeLa	viability after 15 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.1672462642062552	[470]	[128,246,133]	-1	hSpCas9	negative selection	1614003
48121913	48121936	15	+	26627737	HeLa	viability after 15 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.7702342454202005	[1002]	[334,214,160]	-6	hSpCas9	negative selection	1614004
48121059	48121082	15	+	26627737	HeLa	viability after 18 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.38271709963890804	[531]	[116,132,162]	-3	hSpCas9	negative selection	1696316
48121098	48121121	15	-	26627737	HeLa	viability after 18 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-1.0362988515956848	[418]	[14,80,133]	-7	hSpCas9	negative selection	1696317
48121883	48121906	15	+	26627737	HeLa	viability after 18 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.13704136877408785	[470]	[89,208,133]	-1	hSpCas9	negative selection	1696318
48121913	48121936	15	+	26627737	HeLa	viability after 18 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.7517484906718381	[1002]	[233,173,160]	-6	hSpCas9	negative selection	1696319
48121059	48121082	15	+	26627737	HCT116	viability after 6 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.6832682914533881	[1038]	[289,246]	4	hSpCas9	negative selection	1778631
48121098	48121121	15	-	26627737	HCT116	viability after 6 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-1.8499501096634527	[614]	[40,18]	-8	hSpCas9	negative selection	1778632
48121883	48121906	15	+	26627737	HCT116	viability after 6 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.9611148511009637	[614]	[48,264]	5	hSpCas9	negative selection	1778633
48121913	48121936	15	+	26627737	HCT116	viability after 6 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	1.5030335857915427	[1081]	[271,597]	7	hSpCas9	negative selection	1778634
48121059	48121082	15	+	26627737	HCT116	viability after 8 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.16572070436159236	[634]	[328,286,319]	-2	hSpCas9	negative selection	1860946
48121098	48121121	15	-	26627737	HCT116	viability after 8 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.4148546906400927	[197]	[120,175,138]	4	hSpCas9	negative selection	1860947
48121883	48121906	15	+	26627737	HCT116	viability after 8 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.2063482368311479	[542]	[300,239,237]	-2	hSpCas9	negative selection	1860948
48121913	48121936	15	+	26627737	HCT116	viability after 8 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.2815782704044474	[660]	[252,253,389]	-3	hSpCas9	negative selection	1860949
48121059	48121082	15	+	26627737	HCT116	viability after 9 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.4091285837622304	[1038]	[242,181]	-3	hSpCas9	negative selection	1943261
48121098	48121121	15	-	26627737	HCT116	viability after 9 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.15354563876875812	[614]	[204,164]	1	hSpCas9	negative selection	1943262
48121883	48121906	15	+	26627737	HCT116	viability after 9 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.18207990997905724	[614]	[149,214]	1	hSpCas9	negative selection	1943263
48121913	48121936	15	+	26627737	HCT116	viability after 9 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-1.1025012216252996	[1081]	[114,149]	-7	hSpCas9	negative selection	1943264
48121059	48121082	15	+	26627737	HCT116	viability after 12 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.45036417811941254	[634]	[296,200,228]	-5	hSpCas9	negative selection	2025576
48121098	48121121	15	-	26627737	HCT116	viability after 12 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-0.0349360625426266	[197]	[180,71,43]	0	hSpCas9	negative selection	2025577
48121883	48121906	15	+	26627737	HCT116	viability after 12 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.10417282707170294	[542]	[239,195,360]	-1	hSpCas9	negative selection	2025578
48121913	48121936	15	+	26627737	HCT116	viability after 12 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.06725061879356842	[660]	[414,348,322]	0	hSpCas9	negative selection	2025579
48121059	48121082	15	+	26627737	HCT116	viability after 15 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.2270096130340702	[634]	[445,184,319]	-2	hSpCas9	negative selection	2107891
48121098	48121121	15	-	26627737	HCT116	viability after 15 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-0.4533975595313895	[197]	[114,52,84]	-5	hSpCas9	negative selection	2107892
48121883	48121906	15	+	26627737	HCT116	viability after 15 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.12609700611228758	[542]	[244,309,452]	1	hSpCas9	negative selection	2107893
48121913	48121936	15	+	26627737	HCT116	viability after 15 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.24801712974573198	[660]	[329,375,254]	-3	hSpCas9	negative selection	2107894
48121059	48121082	15	+	26627737	HCT116	viability after 18 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	-0.1263261816628758	[634]	[353,197,297]	-1	hSpCas9	negative selection	2190206
48121098	48121121	15	-	26627737	HCT116	viability after 18 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.22845023919833668	[197]	[118,95,122]	2	hSpCas9	negative selection	2190207
48121883	48121906	15	+	26627737	HCT116	viability after 18 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.07140555026419393	[542]	[247,117,398]	0	hSpCas9	negative selection	2190208
48121913	48121936	15	+	26627737	HCT116	viability after 18 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.03315440195315045	[660]	[327,227,389]	0	hSpCas9	negative selection	2190209
48134258	48134281	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.02468517209862514	[3,4]	[3,2]	0	hSpCas9	positive selection	3020885
48122016	48122039	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	0.3314293395206423	[2,3]	[2,4]	7	hSpCas9	positive selection	3020886
48134432	48134455	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	0.29129609288378333	[3,2]	[4,3]	6	hSpCas9	positive selection	3020887
48121040	48121063	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	0.04840664610796758	[4,4]	[5,2]	1	hSpCas9	positive selection	3020888
48134258	48134281	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.09246437661602276	[3,3]	[3,1]	1	hSpCas9	positive selection	3088743
48122016	48122039	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	-0.010659570653080958	[2,2]	[2,1]	0	hSpCas9	positive selection	3088744
48134432	48134455	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.3825228399372582	[3,3]	[3,0]	-5	hSpCas9	positive selection	3088745
48121040	48121063	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	0.2480704466779563	[4,4]	[4,3]	4	hSpCas9	positive selection	3088746
48134258	48134281	15	-	26780180	HT29	viability (Avana library 4 designs)	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.364531569430122	[]	[]	1	hSpCas9	negative selection	3459409
48122016	48122039	15	-	26780180	HT29	viability (Avana library 4 designs)	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	1.03444894273521	[]	[]	4	hSpCas9	negative selection	3459410
48134431	48134454	15	+	26780180	HT29	viability (Avana library 4 designs)	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	1.52617683868036	[]	[]	6	hSpCas9	negative selection	3459411
48121039	48121062	15	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	0.72968600372569	[]	[]	3	hSpCas9	negative selection	3459412
48121039	48121062	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	-0.652561464558301	[]	[]	-1	hSpCas9	negative selection	3559319
48134258	48134281	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-4.42523733950327	[]	[]	-5	hSpCas9	negative selection	3559320
48122016	48122039	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	-4.24835614286099	[]	[]	-5	hSpCas9	negative selection	3559321
48134431	48134454	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-13.9866960924589	[]	[]	-8	hSpCas9	negative selection	3559322
48121883	48121906	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.00001076386503	[]	[]	1	hSpCas9	negative selection	3559323
48121899	48121922	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	1.09061410929043	[]	[]	1	hSpCas9	negative selection	3559324
48121039	48121062	15	+	26780180	A375	viability (Avana lentiGuide)	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	-2.99709076063036	[]	[]	-5	hSpCas9	negative selection	3667978
48134258	48134281	15	-	26780180	A375	viability (Avana lentiGuide)	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	2.04617208624492	[]	[]	2	hSpCas9	negative selection	3667979
48122016	48122039	15	-	26780180	A375	viability (Avana lentiGuide)	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	1.1544985139122	[]	[]	1	hSpCas9	negative selection	3667980
48134431	48134454	15	+	26780180	A375	viability (Avana lentiGuide)	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-2.21696743164553	[]	[]	-4	hSpCas9	negative selection	3667981
48121883	48121906	15	+	26780180	A375	viability (Avana lentiGuide)	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-1.90789921650516	[]	[]	-3	hSpCas9	negative selection	3667982
48121899	48121922	15	-	26780180	A375	viability (Avana lentiGuide)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	-4.10361122040971	[]	[]	-7	hSpCas9	negative selection	3667983
48121039	48121062	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	-0.27117182380053256	[5]	[4,4]	-4	hSpCas9	positive selection	3776585
48134258	48134281	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.45033459618041716	[6]	[5,3]	-6	hSpCas9	positive selection	3776586
48122016	48122039	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	-0.5580970706598117	[5]	[3,3]	-7	hSpCas9	positive selection	3776587
48134431	48134454	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.6384607136824181	[9]	[5,5]	-7	hSpCas9	positive selection	3776588
48121883	48121906	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.11245087731281973	[4]	[5,4]	3	hSpCas9	positive selection	3776589
48121899	48121922	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.08556314657067593	[6]	[6,6]	2	hSpCas9	positive selection	3776590
48121039	48121062	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAAATGCAGACAAAAGGGGG	SLC24A5	ENSG00000188467	0.3917599873707363	[6]	[7,6]	9	hSpCas9	positive selection	3885192
48134258	48134281	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.0935165367293486	[6]	[6,3]	-1	hSpCas9	positive selection	3885193
48122016	48122039	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATTCACTGATGATTTCCAGGG	SLC24A5	ENSG00000188467	0.2807624751651778	[4]	[5,4]	7	hSpCas9	positive selection	3885194
48134431	48134454	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	0.24979516518932904	[4]	[4,4]	6	hSpCas9	positive selection	3885195
48121883	48121906	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.3196322387872335	[5]	[5,5]	8	hSpCas9	positive selection	3885196
48121899	48121922	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.3103663671446959	[7]	[8,7]	8	hSpCas9	positive selection	3885197
48121899	48121922	15	-	26780180	A375	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.233675834966933	[]	[]	0	hSpCas9	negative selection	3995262
48134253	48134276	15	+	26780180	A375	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.553831853520325	[]	[]	1	hSpCas9	negative selection	3995263
48121899	48121922	15	-	26780180	HT29	viability (GeCKOv2 library)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	-0.0619177274436442	[]	[]	-2	hSpCas9	negative selection	4103228
48134253	48134276	15	+	26780180	HT29	viability (GeCKOv2 library)	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.0340427087546338	[]	[]	0	hSpCas9	negative selection	4103229
48121899	48121922	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.363118996051459	[3]	[5,2]	7	hSpCas9	positive selection	4298257
48134253	48134276	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.28185328638741736	[4]	[5,4]	5	hSpCas9	positive selection	4298259
48121884	48121906	15	+	27760321	OCIAML3	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.8701752217876421	[511,406]	[549,786]	8	hSpCas9	negative selection	4439761
48134258	48134280	15	-	27760321	OCIAML3	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.4234398074437541	[198,172]	[168,227]	5	hSpCas9	negative selection	4439762
48134432	48134454	15	+	27760321	OCIAML3	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.19519984139032864	[1,0]	[0,0]	-2	hSpCas9	negative selection	4439763
48121884	48121906	15	+	27760321	OCIAML2	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.6542292203622385	[511,406]	[517,664]	8	hSpCas9	negative selection	4523224
48134258	48134280	15	-	27760321	OCIAML2	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.15716628365258156	[198,172]	[112,238]	2	hSpCas9	negative selection	4523225
48134432	48134454	15	+	27760321	OCIAML2	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.24394520665537733	[1,0]	[0,0]	-3	hSpCas9	negative selection	4523226
48121884	48121906	15	+	27760321	MV411	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.9621689709617602	[511,406]	[529,672]	7	hSpCas9	negative selection	4606687
48134258	48134280	15	-	27760321	MV411	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.5106872270499886	[198,172]	[227,93]	3	hSpCas9	negative selection	4606688
48134432	48134454	15	+	27760321	MV411	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	0.049878727524353295	[1,0]	[0,0]	0	hSpCas9	negative selection	4606689
48121884	48121906	15	+	27760321	HL60	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.10999450893559899	[511,406]	[356,450]	1	hSpCas9	negative selection	4690150
48134258	48134280	15	-	27760321	HL60	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.25893766114326133	[198,172]	[209,150]	3	hSpCas9	negative selection	4690151
48134432	48134454	15	+	27760321	HL60	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.2579914342697833	[1,0]	[0,0]	-3	hSpCas9	negative selection	4690152
48121884	48121906	15	+	27760321	HT1080	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.2623823230648208	[406,317]	[513,162]	6	hSpCas9	negative selection	4773613
48134258	48134280	15	-	27760321	HT1080	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	2.641614320807543	[172,134]	[431,328]	9	hSpCas9	negative selection	4773614
48134432	48134454	15	+	27760321	HT1080	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4773615
48121884	48121906	15	+	27760321	HT29	viability after 7 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.4235450192810776	[406,317]	[561,756,548]	6	hSpCas9	negative selection	4857076
48134258	48134280	15	-	27760321	HT29	viability after 7 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.04272580660896108	[172,134]	[284,92,210]	0	hSpCas9	negative selection	4857077
48134432	48134454	15	+	27760321	HT29	viability after 7 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4857078
48121884	48121906	15	+	27760321	HT29	viability after 25 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.8516401853817371	[406,317]	[935,484,815]	8	hSpCas9	negative selection	4940539
48134258	48134280	15	-	27760321	HT29	viability after 25 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.6210457116654466	[172,134]	[279,251,279]	7	hSpCas9	negative selection	4940540
48134432	48134454	15	+	27760321	HT29	viability after 25 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4940541
48121884	48121906	15	+	27760321	HT29	viability after 22 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.8232391338365533	[406,317]	[990,677,546]	8	hSpCas9	negative selection	5024002
48134258	48134280	15	-	27760321	HT29	viability after 22 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	1.1543679744240667	[172,134]	[468,303,413]	9	hSpCas9	negative selection	5024003
48134432	48134454	15	+	27760321	HT29	viability after 22 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5024004
48121884	48121906	15	+	27760321	HT29	viability after 19 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.9697562090308862	[406,317]	[783,847,800]	8	hSpCas9	negative selection	5107465
48134258	48134280	15	-	27760321	HT29	viability after 19 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.4166198782522754	[172,134]	[366,252,103]	4	hSpCas9	negative selection	5107466
48134432	48134454	15	+	27760321	HT29	viability after 19 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5107467
48121884	48121906	15	+	27760321	HT29	viability after 16 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.5513780325895874	[406,317]	[751,554,491]	6	hSpCas9	negative selection	5190928
48134258	48134280	15	-	27760321	HT29	viability after 16 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.2655480127204831	[172,134]	[261,225,137]	3	hSpCas9	negative selection	5190929
48134432	48134454	15	+	27760321	HT29	viability after 16 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5190930
48121884	48121906	15	+	27760321	HT29	viability after 13 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.8103097685229051	[406,317]	[578,593,1021]	9	hSpCas9	negative selection	5274391
48134258	48134280	15	-	27760321	HT29	viability after 13 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.1601228262812333	[172,134]	[207,74,308]	2	hSpCas9	negative selection	5274392
48134432	48134454	15	+	27760321	HT29	viability after 13 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5274393
48121884	48121906	15	+	27760321	HT29	viability after 10 days	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.525855777301095	[406,317]	[732,695,529]	7	hSpCas9	negative selection	5357854
48134258	48134280	15	-	27760321	HT29	viability after 10 days	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.20270377653699811	[172,134]	[225,202,233]	2	hSpCas9	negative selection	5357855
48134432	48134454	15	+	27760321	HT29	viability after 10 days	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5357856
48121884	48121906	15	+	27760321	MOLM13	viability	CATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.1678235943263267	[511,406]	[257,204]	-1	hSpCas9	negative selection	5441317
48134258	48134280	15	-	27760321	MOLM13	viability	ACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.486246353053956	[198,172]	[37,105]	-3	hSpCas9	negative selection	5441318
48134432	48134454	15	+	27760321	MOLM13	viability	TAGGTGTATTTATCACAAAGGG	SLC24A5	ENSG00000188467	0.27593554035194856	[1,0]	[0,0]	2	hSpCas9	negative selection	5441319
48121059	48121082	15	+	27661255	K562	viability	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.09998478459920424	[1242,1299]	[1179,1008]	3	dCas9-KRAB	negative selection	5511649
48121098	48121121	15	-	27661255	K562	viability	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.06714222991357066	[1098,1109]	[1016,844]	2	dCas9-KRAB	negative selection	5511650
48121477	48121500	15	-	27661255	K562	viability	GCAGAGCCTAAATTGTTCACAGG	SLC24A5	ENSG00000188467	0.10224155240358546	[386,328]	[356,265]	3	dCas9-KRAB	negative selection	5511651
48121899	48121922	15	-	27260156	BXPC3	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5761534739293854	[793]	[1175,1173,1340,1266]	9	hSpCas9	negative selection	5570717
48134253	48134276	15	+	27260156	BXPC3	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.48690745064364194	[1853]	[2360,2470,2775,3375]	8	hSpCas9	negative selection	5570719
48121899	48121922	15	-	27260156	A673	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.4331221775806855	[793]	[1384,1108,1253,1421]	8	hSpCas9	negative selection	5691968
48134253	48134276	15	+	27260156	A673	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4919540006262557	[1853]	[3443,3082,3105,2908]	9	hSpCas9	negative selection	5691970
48121899	48121922	15	-	27260156	A375	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.8439148714373785	[793]	[1509,1719,1704,1716]	9	hSpCas9	negative selection	5813219
48134253	48134276	15	+	27260156	A375	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.7331874234338889	[1853]	[3555,4140,3601,3207]	9	hSpCas9	negative selection	5813221
48121899	48121922	15	-	27260156	COLO741	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6679153523986716	[793]	[1673,1704,1468]	9	hSpCas9	negative selection	5934470
48134253	48134276	15	+	27260156	COLO741	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5056002010680323	[1853]	[3733,3398,3006]	8	hSpCas9	negative selection	5934472
48121899	48121922	15	-	27260156	CAL120	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.7112884252645206	[793]	[1792,1368,1714]	9	hSpCas9	negative selection	6055721
48134253	48134276	15	+	27260156	CAL120	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6610454854751335	[1853]	[4817,3231,3078]	8	hSpCas9	negative selection	6055723
48121899	48121922	15	-	27260156	CADOES1	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.3572884120839357	[793]	[829,857,1022,1077]	6	hSpCas9	negative selection	6176972
48134253	48134276	15	+	27260156	CADOES1	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5025697385812036	[1853]	[2257,2500,2524,2489]	8	hSpCas9	negative selection	6176974
48121899	48121922	15	-	27260156	EWS502	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5250860711159797	[793]	[1126,1269,1302,1139]	8	hSpCas9	negative selection	6298223
48134253	48134276	15	+	27260156	EWS502	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6814076562644931	[1853]	[2768,3122,3099,3676]	9	hSpCas9	negative selection	6298225
48121899	48121922	15	-	27260156	EW8	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.17475619945771814	[793]	[757,790,619,755]	3	hSpCas9	negative selection	6419474
48134253	48134276	15	+	27260156	EW8	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5283502832112714	[1853]	[2660,2348,1926,1821]	8	hSpCas9	negative selection	6419476
48121899	48121922	15	-	27260156	CORL105	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.45263679176555205	[793]	[1519,1039,1421,1142]	8	hSpCas9	negative selection	6540725
48134253	48134276	15	+	27260156	CORL105	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5367969181362735	[1853]	[3146,3033,3475,2990]	8	hSpCas9	negative selection	6540727
48121899	48121922	15	-	27260156	HS294T	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	1.00083046026932	[793]	[565,778,541,557]	9	hSpCas9	negative selection	6661976
48134253	48134276	15	+	27260156	HS294T	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6074631946603848	[1853]	[1010,973,1099,1331]	7	hSpCas9	negative selection	6661978
48121899	48121922	15	-	27260156	HCC44	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6262205305903321	[793]	[1443,1002,1918,1320]	8	hSpCas9	negative selection	6783227
48134253	48134276	15	+	27260156	HCC44	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4601373774527735	[1853]	[3395,2296,2998,2969]	7	hSpCas9	negative selection	6783229
48121899	48121922	15	-	27260156	G402	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.36555350496582695	[793]	[1319,1467,1224,1009]	4	hSpCas9	negative selection	6904478
48134253	48134276	15	+	27260156	G402	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.8091945982578537	[1853]	[5145,3657,4041,3185]	8	hSpCas9	negative selection	6904480
48121899	48121922	15	-	27260156	L33	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5513953053025666	[793]	[1456,396,702,1102]	9	hSpCas9	negative selection	7025729
48134253	48134276	15	+	27260156	L33	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4108398186055773	[1853]	[2452,949,1676,2420]	8	hSpCas9	negative selection	7025731
48121899	48121922	15	-	27260156	K562	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.7297331840339332	[793]	[1166,943,1876,721]	8	hSpCas9	negative selection	7146980
48134253	48134276	15	+	27260156	K562	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6005135603356893	[1853]	[2119,2292,3105,2416]	7	hSpCas9	negative selection	7146982
48121899	48121922	15	-	27260156	HT29	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5491904326915356	[793]	[1611,1560,1313,1205]	9	hSpCas9	negative selection	7268231
48134253	48134276	15	+	27260156	HT29	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5947525424137554	[1853]	[3615,4193,3125,2811]	9	hSpCas9	negative selection	7268233
48121899	48121922	15	-	27260156	MHHES1	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6119010892912826	[793]	[1413,1295,1466,1277]	9	hSpCas9	negative selection	7389482
48134253	48134276	15	+	27260156	MHHES1	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4937467620019036	[1853]	[3114,3348,3520,1997]	8	hSpCas9	negative selection	7389484
48121899	48121922	15	-	27260156	MEWO	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6219008612450341	[793]	[1280,1123,1050]	9	hSpCas9	negative selection	7510733
48134253	48134276	15	+	27260156	MEWO	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.31279212960388225	[1853]	[2347,1835,2317]	6	hSpCas9	negative selection	7510735
48121899	48121922	15	-	27260156	LNCAPCLONEFGC	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6694543647153719	[793]	[1159,1016,1230,1187]	9	hSpCas9	negative selection	7631984
48134253	48134276	15	+	27260156	LNCAPCLONEFGC	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5912399639191483	[1853]	[2504,2312,3191,2221]	8	hSpCas9	negative selection	7631986
48121899	48121922	15	-	27260156	PANC0327	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6172597193045015	[793]	[1419,645,973,1370]	8	hSpCas9	negative selection	7753235
48134253	48134276	15	+	27260156	PANC0327	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.7038958901896777	[1853]	[3218,2069,2342,3219]	8	hSpCas9	negative selection	7753237
48121899	48121922	15	-	27260156	NCIH2009	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6496463140777635	[793]	[2106,1380,1808]	8	hSpCas9	negative selection	7874486
48134253	48134276	15	+	27260156	NCIH2009	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6568007603097441	[1853]	[4626,4029,3695]	8	hSpCas9	negative selection	7874488
48121899	48121922	15	-	27260156	NCIH1373	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	1.0264779955526653	[793]	[1498,1764,2339,411]	9	hSpCas9	negative selection	7995737
48134253	48134276	15	+	27260156	NCIH1373	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.8588812419121412	[1853]	[4219,3539,3226,1103]	8	hSpCas9	negative selection	7995739
48121899	48121922	15	-	27260156	PATU8902	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.8864976789155494	[793]	[2440,1902,1515,2484]	8	hSpCas9	negative selection	8116988
48134253	48134276	15	+	27260156	PATU8902	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.921489939956746	[1853]	[4031,4893,4219,6789]	8	hSpCas9	negative selection	8116990
48121899	48121922	15	-	27260156	PANC1	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6484964691629254	[793]	[1112,1409,888,935]	9	hSpCas9	negative selection	8238239
48134253	48134276	15	+	27260156	PANC1	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6761909663715344	[1853]	[2670,3207,2335,2122]	9	hSpCas9	negative selection	8238241
48121899	48121922	15	-	27260156	PANC0813	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5924394812072129	[793]	[1625,1344,1326,1347]	8	hSpCas9	negative selection	8359490
48134253	48134276	15	+	27260156	PANC0813	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6601821364868377	[1853]	[3873,3600,3249,3093]	9	hSpCas9	negative selection	8359492
48121899	48121922	15	-	27260156	RDES	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6020026969338717	[793]	[1047,1366,1529,1683]	8	hSpCas9	negative selection	8480741
48134253	48134276	15	+	27260156	RDES	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.6347301573950737	[1853]	[2878,3262,3602,3533]	8	hSpCas9	negative selection	8480743
48121899	48121922	15	-	27260156	PC3	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.335244598443333	[793]	[569,1194,1533,987]	7	hSpCas9	negative selection	8601992
48134253	48134276	15	+	27260156	PC3	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.3999596318670444	[1853]	[1632,2387,3698,2635]	8	hSpCas9	negative selection	8601994
48121899	48121922	15	-	27260156	PATU8988T	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.8083779721365372	[793]	[1025,1860,1220,1313]	9	hSpCas9	negative selection	8723243
48134253	48134276	15	+	27260156	PATU8988T	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4291489125993344	[1853]	[2083,2901,2352,2350]	7	hSpCas9	negative selection	8723245
48121899	48121922	15	-	27260156	T47D	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6006146761566549	[793]	[1390,1359,1414,1448]	9	hSpCas9	negative selection	8844494
48134253	48134276	15	+	27260156	T47D	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4747637819774604	[1853]	[2915,2653,3070,3405]	8	hSpCas9	negative selection	8844496
48121899	48121922	15	-	27260156	SU8686	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.6706531258285082	[793]	[1194,1117,1435,1288]	9	hSpCas9	negative selection	8965745
48134253	48134276	15	+	27260156	SU8686	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.4223267556341148	[1853]	[2355,2494,2382,2633]	7	hSpCas9	negative selection	8965747
48121899	48121922	15	-	27260156	SKES1	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.579595573704335	[793]	[1304,1276,1031,1142]	9	hSpCas9	negative selection	9086996
48134253	48134276	15	+	27260156	SKES1	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.47618451058696243	[1853]	[2889,2973,2486,2066]	8	hSpCas9	negative selection	9086998
48121899	48121922	15	-	27260156	TOV112D	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.452937113881972	[793]	[888,1665,1064,863]	8	hSpCas9	negative selection	9208247
48134253	48134276	15	+	27260156	TOV112D	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.5804113946763279	[1853]	[3314,3331,2309,2338]	9	hSpCas9	negative selection	9208249
48121899	48121922	15	-	27260156	TC71	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.5255671171811067	[793]	[1148,1290,1136,1334]	9	hSpCas9	negative selection	9329498
48134253	48134276	15	+	27260156	TC71	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.33594417001168075	[1853]	[2090,2523,2696,2738]	7	hSpCas9	negative selection	9329500
48121899	48121922	15	-	27260156	TC32	viability	CTGTCTCGTGAAAAACCCTTCGG	SLC24A5	ENSG00000188467	0.33135424643875666	[793]	[932,679,1259,982]	6	hSpCas9	negative selection	9450749
48134253	48134276	15	+	27260156	TC32	viability	TTCAGCCCTTGGATTGTCTCAGG	SLC24A5	ENSG00000188467	0.684468399297598	[1853]	[2725,2225,3309,3097]	9	hSpCas9	negative selection	9450751
48121059	48121082	15	+	27869803	HPAFII	viability after 27 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.8119837838370166	[365]	[255,405,NaN]	6	hSpCas9	negative selection	9553857
48121098	48121121	15	-	27869803	HPAFII	viability after 27 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.14358041976640312	[187]	[124,95,NaN]	1	hSpCas9	negative selection	9553858
48121883	48121906	15	+	27869803	HPAFII	viability after 27 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.7177332863583693	[228]	[257,147,NaN]	6	hSpCas9	negative selection	9553859
48121913	48121936	15	+	27869803	HPAFII	viability after 27 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.27938719228323816	[423]	[83,425,NaN]	2	hSpCas9	negative selection	9553860
48121059	48121082	15	+	27869803	HPAFII	viability after 15 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.44573487608918516	[365]	[507,552,NaN]	5	hSpCas9	negative selection	9636306
48121098	48121121	15	-	27869803	HPAFII	viability after 15 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.4250054604601778	[187]	[446,161,NaN]	5	hSpCas9	negative selection	9636307
48121883	48121906	15	+	27869803	HPAFII	viability after 15 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.32949704506113736	[228]	[410,245,NaN]	4	hSpCas9	negative selection	9636308
48121913	48121936	15	+	27869803	HPAFII	viability after 15 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.3030575621508121	[423]	[348,381,NaN]	-3	hSpCas9	negative selection	9636309
48121059	48121082	15	+	27869803	ASPC1	viability after 36 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	1.1758527498711635	[800]	[441,1490,75]	9	hSpCas9	negative selection	9718755
48121098	48121121	15	-	27869803	ASPC1	viability after 36 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	-0.4673403101377914	[371]	[58,227,10]	-5	hSpCas9	negative selection	9718756
48121883	48121906	15	+	27869803	ASPC1	viability after 36 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.2048308843890989	[669]	[304,349,177]	2	hSpCas9	negative selection	9718757
48121913	48121936	15	+	27869803	ASPC1	viability after 36 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	-0.025997119689562642	[867]	[436,310,185]	0	hSpCas9	negative selection	9718758
48121059	48121082	15	+	27869803	PATU8988S	viability after 35 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.35425423078994783	[756]	[493,284,NaN]	4	hSpCas9	negative selection	9801204
48121098	48121121	15	-	27869803	PATU8988S	viability after 35 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.09308108046013713	[390]	[154,180,NaN]	1	hSpCas9	negative selection	9801205
48121883	48121906	15	+	27869803	PATU8988S	viability after 35 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.09484514080531475	[677]	[343,238,NaN]	1	hSpCas9	negative selection	9801206
48121913	48121936	15	+	27869803	PATU8988S	viability after 35 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.14673087191611678	[677]	[213,390,NaN]	1	hSpCas9	negative selection	9801207
48121059	48121082	15	+	27869803	PATU8988S	viability after 31 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.5859809996749823	[756]	[515,372,NaN]	7	hSpCas9	negative selection	9883653
48121098	48121121	15	-	27869803	PATU8988S	viability after 31 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.2402306104017445	[390]	[166,205,NaN]	3	hSpCas9	negative selection	9883654
48121883	48121906	15	+	27869803	PATU8988S	viability after 31 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.26919061238464875	[677]	[349,294,NaN]	3	hSpCas9	negative selection	9883655
48121913	48121936	15	+	27869803	PATU8988S	viability after 31 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.07870130977849793	[677]	[215,373,NaN]	1	hSpCas9	negative selection	9883656
48121059	48121082	15	+	27869803	HPAFII	viability after 35 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.8542698180618536	[365]	[270,406,NaN]	5	hSpCas9	negative selection	9966102
48121098	48121121	15	-	27869803	HPAFII	viability after 35 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.4658765400931756	[187]	[90,176,NaN]	3	hSpCas9	negative selection	9966103
48121883	48121906	15	+	27869803	HPAFII	viability after 35 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.7761528447646129	[228]	[214,179,NaN]	5	hSpCas9	negative selection	9966104
48121913	48121936	15	+	27869803	HPAFII	viability after 35 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.8601526144727262	[423]	[129,681,NaN]	5	hSpCas9	negative selection	9966105
48121059	48121082	15	+	27869803	HPAFII	viability after 31 days	GGGCCAAACATGGGCGAGAAGGG	SLC24A5	ENSG00000188467	0.6859907312297372	[365]	[228,440,NaN]	5	hSpCas9	negative selection	10048551
48121098	48121121	15	-	27869803	HPAFII	viability after 31 days	GCAGATGTGCAGTGGCCCACAGG	SLC24A5	ENSG00000188467	0.5698543531417221	[187]	[80,238,NaN]	4	hSpCas9	negative selection	10048552
48121883	48121906	15	+	27869803	HPAFII	viability after 31 days	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.0143933736041775	[228]	[250,268,NaN]	7	hSpCas9	negative selection	10048553
48121913	48121936	15	+	27869803	HPAFII	viability after 31 days	ACGAGACAGGAGCGCAGAGATGG	SLC24A5	ENSG00000188467	0.31469521120049004	[423]	[93,515,NaN]	2	hSpCas9	negative selection	10048554
48121106	48121129	15	-	28162770	P31FUJ	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.03892690297182111	[192]	[232]	0	hSpCas9	negative selection	10235805
48121058	48121081	15	+	28162770	P31FUJ	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.5272470028648688	[61]	[104]	6	hSpCas9	negative selection	10235806
48134258	48134281	15	-	28162770	P31FUJ	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.4420301665523786	[199]	[172]	-4	hSpCas9	negative selection	10235807
48121883	48121906	15	+	28162770	P31FUJ	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.0981548562741095	[222]	[560]	9	hSpCas9	negative selection	10235808
48134283	48134306	15	+	28162770	P31FUJ	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.43377406186042955	[62]	[99]	5	hSpCas9	negative selection	10235809
48134499	48134522	15	-	28162770	P31FUJ	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.020316732554332584	[291]	[347]	0	hSpCas9	negative selection	10235810
48121106	48121129	15	-	28162770	TF1	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10405171
48121058	48121081	15	+	28162770	TF1	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10405172
48134258	48134281	15	-	28162770	TF1	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10405173
48121883	48121906	15	+	28162770	TF1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[275]	1	hSpCas9	negative selection	10405174
48134283	48134306	15	+	28162770	TF1	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10405175
48134499	48134522	15	-	28162770	TF1	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10405176
48121106	48121129	15	-	28162770	SKM1	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.6269857156168628	[75]	[86]	-5	hSpCas9	negative selection	10574537
48121058	48121081	15	+	28162770	SKM1	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.3796321631476449	[19]	[45]	3	hSpCas9	negative selection	10574538
48134258	48134281	15	-	28162770	SKM1	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.1881295968199031	[57]	[89]	-2	hSpCas9	negative selection	10574539
48121883	48121906	15	+	28162770	SKM1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.20774564537204668	[47]	[97]	2	hSpCas9	negative selection	10574540
48134283	48134306	15	+	28162770	SKM1	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	-0.7189082050579021	[26]	[28]	-5	hSpCas9	negative selection	10574541
48134499	48134522	15	-	28162770	SKM1	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.14483143804279525	[43]	[85]	1	hSpCas9	negative selection	10574542
48121106	48121129	15	-	28162770	SKM1	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.6269857156168628	[75]	[86]	-5	hSpCas9	negative selection	10743903
48121058	48121081	15	+	28162770	SKM1	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.3796321631476449	[19]	[45]	3	hSpCas9	negative selection	10743904
48134258	48134281	15	-	28162770	SKM1	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.1881295968199031	[57]	[89]	-2	hSpCas9	negative selection	10743905
48121883	48121906	15	+	28162770	SKM1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.20774564537204668	[47]	[97]	2	hSpCas9	negative selection	10743906
48134283	48134306	15	+	28162770	SKM1	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	-0.7189082050579021	[26]	[28]	-5	hSpCas9	negative selection	10743907
48134499	48134522	15	-	28162770	SKM1	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.14483143804279525	[43]	[85]	1	hSpCas9	negative selection	10743908
48121106	48121129	15	-	28162770	PL21	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.4352278396690792	[232]	[74]	-3	hSpCas9	negative selection	10913269
48121058	48121081	15	+	28162770	PL21	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	1.1412459254357514	[74]	[71]	8	hSpCas9	negative selection	10913270
48134258	48134281	15	-	28162770	PL21	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.6307739688191827	[183]	[123]	5	hSpCas9	negative selection	10913271
48121883	48121906	15	+	28162770	PL21	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.8421832104177437	[222]	[173]	7	hSpCas9	negative selection	10913272
48134283	48134306	15	+	28162770	PL21	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	-2.4519370820903728	[87]	[6]	-9	hSpCas9	negative selection	10913273
48134499	48134522	15	-	28162770	PL21	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.38799962986633907	[150]	[85]	3	hSpCas9	negative selection	10913274
48121106	48121129	15	-	28162770	P31FUJ	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.03892690297182111	[192]	[232]	0	hSpCas9	negative selection	11082635
48121058	48121081	15	+	28162770	P31FUJ	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.5272470028648688	[61]	[104]	6	hSpCas9	negative selection	11082636
48134258	48134281	15	-	28162770	P31FUJ	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.4420301665523786	[199]	[172]	-4	hSpCas9	negative selection	11082637
48121883	48121906	15	+	28162770	P31FUJ	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.0981548562741095	[222]	[560]	9	hSpCas9	negative selection	11082638
48134283	48134306	15	+	28162770	P31FUJ	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.43377406186042955	[62]	[99]	5	hSpCas9	negative selection	11082639
48134499	48134522	15	-	28162770	P31FUJ	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.020316732554332584	[291]	[347]	0	hSpCas9	negative selection	11082640
48121106	48121129	15	-	28162770	OCIAML5	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.9423492954861089	[127]	[443]	7	hSpCas9	negative selection	11252001
48121058	48121081	15	+	28162770	OCIAML5	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.3860931663307676	[38]	[91]	3	hSpCas9	negative selection	11252002
48134258	48134281	15	-	28162770	OCIAML5	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-0.42215579510362294	[192]	[259]	-3	hSpCas9	negative selection	11252003
48121883	48121906	15	+	28162770	OCIAML5	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.9193090540880404	[115]	[395]	7	hSpCas9	negative selection	11252004
48134283	48134306	15	+	28162770	OCIAML5	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.7545910009564781	[43]	[133]	6	hSpCas9	negative selection	11252005
48134499	48134522	15	-	28162770	OCIAML5	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.2294633146326015	[171]	[363]	2	hSpCas9	negative selection	11252006
48121106	48121129	15	-	28162770	EOL1	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.3574875961933151	[427]	[175]	-3	hSpCas9	negative selection	11421367
48121058	48121081	15	+	28162770	EOL1	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.2661642013800092	[130]	[82]	2	hSpCas9	negative selection	11421368
48134258	48134281	15	-	28162770	EOL1	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	1.2586849241531144	[352]	[444]	9	hSpCas9	negative selection	11421369
48121883	48121906	15	+	28162770	EOL1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	-0.49048972770830923	[415]	[155]	-4	hSpCas9	negative selection	11421370
48134283	48134306	15	+	28162770	EOL1	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.2856464637385747	[108]	[69]	2	hSpCas9	negative selection	11421371
48134499	48134522	15	-	28162770	EOL1	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	-0.5084116357055716	[188]	[69]	-4	hSpCas9	negative selection	11421372
48121106	48121129	15	-	28162770	MOLM13	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	1.228162349202854	[306]	[519]	8	hSpCas9	negative selection	11590733
48121058	48121081	15	+	28162770	MOLM13	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	1.1407246382910692	[137]	[219]	8	hSpCas9	negative selection	11590734
48134258	48134281	15	-	28162770	MOLM13	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.22961921570412608	[334]	[283]	1	hSpCas9	negative selection	11590735
48121883	48121906	15	+	28162770	MOLM13	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.6707062645442659	[317]	[365]	5	hSpCas9	negative selection	11590736
48134283	48134306	15	+	28162770	MOLM13	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.6714227756297108	[98]	[113]	5	hSpCas9	negative selection	11590737
48134499	48134522	15	-	28162770	MOLM13	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.062070412295113675	[207]	[156]	0	hSpCas9	negative selection	11590738
48121106	48121129	15	-	28162770	HEL	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	1.3106906973925445	[303]	[482]	9	hSpCas9	negative selection	11760099
48121058	48121081	15	+	28162770	HEL	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	-1.3700852083572266	[112]	[27]	-7	hSpCas9	negative selection	11760100
48134258	48134281	15	-	28162770	HEL	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	-1.12279591436262	[254]	[74]	-6	hSpCas9	negative selection	11760101
48121883	48121906	15	+	28162770	HEL	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.1732535486991367	[224]	[324]	8	hSpCas9	negative selection	11760102
48134283	48134306	15	+	28162770	HEL	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.5800030766523945	[93]	[89]	5	hSpCas9	negative selection	11760103
48134499	48134522	15	-	28162770	HEL	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	-0.510884357112855	[197]	[88]	-3	hSpCas9	negative selection	11760104
48121106	48121129	15	-	28162770	MV411	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.1214078977204347	[262]	[240]	1	hSpCas9	negative selection	11929465
48121058	48121081	15	+	28162770	MV411	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	2.240742898208767	[53]	[214]	9	hSpCas9	negative selection	11929466
48134258	48134281	15	-	28162770	MV411	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.6467934278293496	[184]	[243]	6	hSpCas9	negative selection	11929467
48121883	48121906	15	+	28162770	MV411	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.1765540646262655	[218]	[416]	9	hSpCas9	negative selection	11929468
48134283	48134306	15	+	28162770	MV411	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	-0.3290633711901847	[84]	[56]	-2	hSpCas9	negative selection	11929469
48134499	48134522	15	-	28162770	MV411	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	-0.11164354252205311	[117]	[91]	-1	hSpCas9	negative selection	11929470
48121106	48121129	15	-	28162770	MONOMAC1	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.544202233445939	[172]	[135]	-4	hSpCas9	negative selection	12098831
48121058	48121081	15	+	28162770	MONOMAC1	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	-0.8204734955953457	[56]	[36]	-6	hSpCas9	negative selection	12098832
48134258	48134281	15	-	28162770	MONOMAC1	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.7909905112743704	[120]	[239]	7	hSpCas9	negative selection	12098833
48121883	48121906	15	+	28162770	MONOMAC1	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.08863536245397194	[136]	[166]	0	hSpCas9	negative selection	12098834
48134283	48134306	15	+	28162770	MONOMAC1	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	0.8659729504662468	[55]	[116]	7	hSpCas9	negative selection	12098835
48134499	48134522	15	-	28162770	MONOMAC1	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.16175654157967095	[84]	[108]	1	hSpCas9	negative selection	12098836
48121106	48121129	15	-	28162770	OCIAML2	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	0.6610758539696611	[33]	[297]	6	hSpCas9	negative selection	12268197
48121058	48121081	15	+	28162770	OCIAML2	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	1.336725096815443	[11]	[167]	9	hSpCas9	negative selection	12268198
48134258	48134281	15	-	28162770	OCIAML2	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.7517625960942866	[32]	[307]	7	hSpCas9	negative selection	12268199
48121883	48121906	15	+	28162770	OCIAML2	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	0.5335579717212721	[42]	[344]	5	hSpCas9	negative selection	12268200
48134283	48134306	15	+	28162770	OCIAML2	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	1.0187550154967637	[12]	[145]	8	hSpCas9	negative selection	12268201
48134499	48134522	15	-	28162770	OCIAML2	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	0.09008512923231773	[29]	[176]	0	hSpCas9	negative selection	12268202
48121106	48121129	15	-	28162770	OCIAML3	viability	TGAGAGAGGCAGATGTGCAGTGG	SLC24A5	ENSG00000188467	-0.33585545587011545	[73]	[176]	-3	hSpCas9	negative selection	12437563
48121058	48121081	15	+	28162770	OCIAML3	viability	GGGGCCAAACATGGGCGAGAAGG	SLC24A5	ENSG00000188467	0.6470004591796318	[32]	[155]	6	hSpCas9	negative selection	12437564
48134258	48134281	15	-	28162770	OCIAML3	viability	AACATCCTGAGACAATCCAAGGG	SLC24A5	ENSG00000188467	0.8714645804704336	[64]	[358]	7	hSpCas9	negative selection	12437565
48121883	48121906	15	+	28162770	OCIAML3	viability	CCATCATCGGAGTTTCCCGAAGG	SLC24A5	ENSG00000188467	1.139346700289664	[59]	[398]	8	hSpCas9	negative selection	12437566
48134283	48134306	15	+	28162770	OCIAML3	viability	AGGCACAACTTTCATGGCAGCGG	SLC24A5	ENSG00000188467	1.3288244991533769	[11]	[90]	9	hSpCas9	negative selection	12437567
48134499	48134522	15	-	28162770	OCIAML3	viability	CACAGGCAGCACAGATGCCAAGG	SLC24A5	ENSG00000188467	1.062745543465003	[48]	[308]	8	hSpCas9	negative selection	12437568