Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8243
• Symbol: SMC1A
• Description: structural maintenance of chromosomes 1A

DataSource: http://genomecrispr.dkfz.de/#!/results/SMC1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
53409440	53409463	X	-	26472758	Jiyoye	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-2.427401009286755	[213]	[29]	-8	hSpCas9	negative selection	151775
53405253	53405276	X	-	26472758	Jiyoye	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-2.94332186557826	[203]	[19]	-9	hSpCas9	negative selection	151776
53413327	53413350	X	-	26472758	Jiyoye	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	3.4071753815058727	[0]	[7]	9	hSpCas9	negative selection	151777
53413027	53413050	X	-	26472758	Jiyoye	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-2.5045162003664663	[300]	[39]	-9	hSpCas9	negative selection	151778
53413000	53413023	X	-	26472758	Jiyoye	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-4.762749619936439	[71]	[1]	-9	hSpCas9	negative selection	151779
53412973	53412996	X	-	26472758	Jiyoye	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-3.4001795405517306	[83]	[5]	-9	hSpCas9	negative selection	151780
53412907	53412930	X	-	26472758	Jiyoye	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-5.019089373196225	[42]	[0]	-9	hSpCas9	negative selection	151781
53409480	53409503	X	-	26472758	Jiyoye	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	2.8222128807847167	[2]	[15]	9	hSpCas9	negative selection	151782
53409163	53409186	X	-	26472758	Jiyoye	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-5.592824618494127	[255]	[3]	-9	hSpCas9	negative selection	151783
53405507	53405530	X	+	26472758	Jiyoye	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-5.742571737998809	[70]	[0]	-9	hSpCas9	negative selection	151784
53409440	53409463	X	-	26472758	KBM7	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-2.2828417347650154	[974,572]	[88,58]	-8	hSpCas9	negative selection	342893
53405253	53405276	X	-	26472758	KBM7	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-2.8124224152803596	[860,821]	[75,38]	-9	hSpCas9	negative selection	342894
53413327	53413350	X	-	26472758	KBM7	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-1.2251084613058194	[42,71]	[3,18]	-7	hSpCas9	negative selection	342895
53413027	53413050	X	-	26472758	KBM7	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.8033716914520599	[677,699]	[255,124]	-6	hSpCas9	negative selection	342896
53413000	53413023	X	-	26472758	KBM7	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-1.6484739217067697	[241,181]	[59,5]	-8	hSpCas9	negative selection	342897
53412973	53412996	X	-	26472758	KBM7	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.090898400335317	[379,347]	[110,52]	-7	hSpCas9	negative selection	342898
53412907	53412930	X	-	26472758	KBM7	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.51126871051206	[127,96]	[14,3]	-9	hSpCas9	negative selection	342899
53409480	53409503	X	-	26472758	KBM7	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.25100718463924077	[158,170]	[156,35]	2	hSpCas9	negative selection	342900
53409163	53409186	X	-	26472758	KBM7	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.735817938872918	[1162,953]	[105,45]	-9	hSpCas9	negative selection	342901
53405507	53405530	X	+	26472758	KBM7	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-2.6653976325975277	[562,531]	[65,17]	-9	hSpCas9	negative selection	342902
53409440	53409463	X	-	26472758	Raji	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-1.8808071623367675	[364]	[22]	-8	hSpCas9	negative selection	534011
53405253	53405276	X	-	26472758	Raji	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-3.122914084048195	[487]	[12]	-9	hSpCas9	negative selection	534012
53413327	53413350	X	-	26472758	Raji	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	0.0629894160151463	[32]	[7]	0	hSpCas9	negative selection	534013
53413027	53413050	X	-	26472758	Raji	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-4.625066577670114	[318]	[2]	-9	hSpCas9	negative selection	534014
53413000	53413023	X	-	26472758	Raji	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-3.00114092140457	[68]	[1]	-9	hSpCas9	negative selection	534015
53412973	53412996	X	-	26472758	Raji	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.214544559513763	[119]	[11]	-7	hSpCas9	negative selection	534016
53412907	53412930	X	-	26472758	Raji	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-0.9800793058767399	[50]	[5]	-6	hSpCas9	negative selection	534017
53409480	53409503	X	-	26472758	Raji	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-0.7752595139882419	[117]	[15]	-5	hSpCas9	negative selection	534018
53409163	53409186	X	-	26472758	Raji	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-4.489551607013633	[483]	[4]	-9	hSpCas9	negative selection	534019
53405507	53405530	X	+	26472758	Raji	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-0.9630057925177985	[251]	[29]	-6	hSpCas9	negative selection	534020
53409440	53409463	X	-	26472758	K562	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-4.436590460525744	[589]	[22]	-9	hSpCas9	negative selection	725129
53405253	53405276	X	-	26472758	K562	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-4.4185462850559825	[683]	[26]	-9	hSpCas9	negative selection	725130
53413327	53413350	X	-	26472758	K562	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.686318609896439	[60]	[1]	-9	hSpCas9	negative selection	725131
53413027	53413050	X	-	26472758	K562	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.9668132479327791	[557]	[240]	-5	hSpCas9	negative selection	725132
53413000	53413023	X	-	26472758	K562	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-1.649871831162438	[170]	[45]	-7	hSpCas9	negative selection	725133
53412973	53412996	X	-	26472758	K562	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.709121961240893	[274]	[70]	-7	hSpCas9	negative selection	725134
53412907	53412930	X	-	26472758	K562	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-1.941447817644887	[90]	[19]	-7	hSpCas9	negative selection	725135
53409480	53409503	X	-	26472758	K562	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.5329882256073785	[139]	[170]	4	hSpCas9	negative selection	725136
53409163	53409186	X	-	26472758	K562	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-4.727566896163957	[815]	[25]	-9	hSpCas9	negative selection	725137
53405507	53405530	X	+	26472758	K562	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-2.6844981742720706	[395]	[51]	-8	hSpCas9	negative selection	725138
53409106	53409129	X	-	26627737	DLD1	viability	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-6.2352308053018435	[240]	[0,0,0]	-9	hSpCas9	negative selection	846027
53411779	53411802	X	-	26627737	DLD1	viability	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-2.5504052489962894	[957]	[47,33,67]	-9	hSpCas9	negative selection	846028
53412045	53412068	X	-	26627737	DLD1	viability	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-1.0227772675756217	[115]	[1,26,23]	-7	hSpCas9	negative selection	846029
53412979	53413002	X	-	26627737	DLD1	viability	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.6756260130756986	[681]	[50,53,0]	-9	hSpCas9	negative selection	846030
53413255	53413278	X	-	26627737	DLD1	viability	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.5148315659037834	[201]	[0,17,13]	-9	hSpCas9	negative selection	846031
53415029	53415052	X	+	26627737	DLD1	viability	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-4.722776051472424	[500]	[1,15,0]	-9	hSpCas9	negative selection	846032
53409106	53409129	X	-	26627737	GBM cells	viability after 5 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-1.1941955295057958	[127]	[17,41]	-9	hSpCas9	negative selection	928342
53411779	53411802	X	-	26627737	GBM cells	viability after 5 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.23962606776003614	[556]	[239,265]	-4	hSpCas9	negative selection	928343
53412045	53412068	X	-	26627737	GBM cells	viability after 5 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.22307664949292505	[36]	[22,10]	-3	hSpCas9	negative selection	928344
53412979	53413002	X	-	26627737	GBM cells	viability after 5 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.6741745255471788	[362]	[135,107]	-8	hSpCas9	negative selection	928345
53413255	53413278	X	-	26627737	GBM cells	viability after 5 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	0.16425844140668033	[103]	[55,68]	2	hSpCas9	negative selection	928346
53415029	53415052	X	+	26627737	GBM cells	viability after 5 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-0.2575312125177098	[252]	[139,86]	-4	hSpCas9	negative selection	928347
53409106	53409129	X	-	26627737	GBM cells	viability after 13 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-2.6317125301785698	[127]	[8,12]	-9	hSpCas9	negative selection	1010657
53411779	53411802	X	-	26627737	GBM cells	viability after 13 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.6187793015171927	[556]	[230,168]	-6	hSpCas9	negative selection	1010658
53412045	53412068	X	-	26627737	GBM cells	viability after 13 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.5922422523506738	[36]	[25,2]	-6	hSpCas9	negative selection	1010659
53412979	53413002	X	-	26627737	GBM cells	viability after 13 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.4425452997367946	[362]	[209,91]	-5	hSpCas9	negative selection	1010660
53413255	53413278	X	-	26627737	GBM cells	viability after 13 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.3989959980173381	[103]	[44,40]	-5	hSpCas9	negative selection	1010661
53415029	53415052	X	+	26627737	GBM cells	viability after 13 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-1.3699708373250468	[252]	[67,40]	-8	hSpCas9	negative selection	1010662
53409106	53409129	X	-	26627737	GBM cells	viability after 21 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-2.6045925298200476	[127]	[12,9]	-9	hSpCas9	negative selection	1092972
53411779	53411802	X	-	26627737	GBM cells	viability after 21 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.9046201035984313	[556]	[169,153]	-7	hSpCas9	negative selection	1092973
53412045	53412068	X	-	26627737	GBM cells	viability after 21 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-1.5310543154103482	[36]	[7,5]	-8	hSpCas9	negative selection	1092974
53412979	53413002	X	-	26627737	GBM cells	viability after 21 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.8818258579500649	[362]	[64,42]	-8	hSpCas9	negative selection	1092975
53413255	53413278	X	-	26627737	GBM cells	viability after 21 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.3809526818257667	[103]	[45,40]	-3	hSpCas9	negative selection	1092976
53415029	53415052	X	+	26627737	GBM cells	viability after 21 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-2.4841300615921007	[252]	[22,25]	-9	hSpCas9	negative selection	1092977
53409106	53409129	X	-	26627737	RPE1	viability after 9 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-3.4944784711274934	[35]	[0,0]	-9	hSpCas9	negative selection	1175287
53411779	53411802	X	-	26627737	RPE1	viability after 9 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.2787460721117727	[1369]	[157,200]	-7	hSpCas9	negative selection	1175288
53412045	53412068	X	-	26627737	RPE1	viability after 9 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.795280962765234	[213]	[59,10]	-5	hSpCas9	negative selection	1175289
53412979	53413002	X	-	26627737	RPE1	viability after 9 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.811726356581119	[1748]	[70,86]	-9	hSpCas9	negative selection	1175290
53413255	53413278	X	-	26627737	RPE1	viability after 9 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.9386355325407595	[448]	[23,136]	-6	hSpCas9	negative selection	1175291
53415029	53415052	X	+	26627737	RPE1	viability after 9 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-2.5396515608592614	[953]	[77,16]	-9	hSpCas9	negative selection	1175292
53409106	53409129	X	-	26627737	RPE1	viability after 12 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-3.2738135897691754	[35]	[0,0]	-9	hSpCas9	negative selection	1257602
53411779	53411802	X	-	26627737	RPE1	viability after 12 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.8837071415669642	[1369]	[164,235]	-6	hSpCas9	negative selection	1257603
53412045	53412068	X	-	26627737	RPE1	viability after 12 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.9467325951030909	[213]	[40,17]	-6	hSpCas9	negative selection	1257604
53412979	53413002	X	-	26627737	RPE1	viability after 12 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.731399273559067	[1748]	[141,140]	-8	hSpCas9	negative selection	1257605
53413255	53413278	X	-	26627737	RPE1	viability after 12 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.9830473083254213	[448]	[78,41]	-6	hSpCas9	negative selection	1257606
53415029	53415052	X	+	26627737	RPE1	viability after 12 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-2.4030966067141413	[953]	[29,67]	-9	hSpCas9	negative selection	1257607
53409106	53409129	X	-	26627737	RPE1	viability after 15 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-3.3481761275704187	[35]	[0,0]	-9	hSpCas9	negative selection	1339917
53411779	53411802	X	-	26627737	RPE1	viability after 15 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.7533600062270494	[1369]	[319,142]	-5	hSpCas9	negative selection	1339918
53412045	53412068	X	-	26627737	RPE1	viability after 15 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.8864446156508305	[213]	[46,18]	-5	hSpCas9	negative selection	1339919
53412979	53413002	X	-	26627737	RPE1	viability after 15 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.748585965611766	[1748]	[66,79]	-9	hSpCas9	negative selection	1339920
53413255	53413278	X	-	26627737	RPE1	viability after 15 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.173910487633566	[448]	[47,8]	-8	hSpCas9	negative selection	1339921
53415029	53415052	X	+	26627737	RPE1	viability after 15 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-2.802965539843937	[953]	[0,74]	-9	hSpCas9	negative selection	1339922
53409106	53409129	X	-	26627737	RPE1	viability after 18 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-3.28025674134157	[35]	[0,0]	-9	hSpCas9	negative selection	1422232
53411779	53411802	X	-	26627737	RPE1	viability after 18 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.0680271086644455	[1369]	[200,149]	-6	hSpCas9	negative selection	1422233
53412045	53412068	X	-	26627737	RPE1	viability after 18 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.7693721780961627	[213]	[44,21]	-5	hSpCas9	negative selection	1422234
53412979	53413002	X	-	26627737	RPE1	viability after 18 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-3.888641493291928	[1748]	[27,35]	-9	hSpCas9	negative selection	1422235
53413255	53413278	X	-	26627737	RPE1	viability after 18 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.3902243063117217	[448]	[40,3]	-8	hSpCas9	negative selection	1422236
53415029	53415052	X	+	26627737	RPE1	viability after 18 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-4.978569398387006	[953]	[12,2]	-9	hSpCas9	negative selection	1422237
53409106	53409129	X	-	26627737	HeLa	viability after 8 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-0.8287916750245248	[164]	[2,83,26]	-7	hSpCas9	negative selection	1504547
53411779	53411802	X	-	26627737	HeLa	viability after 8 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.48334165709486143	[1035]	[543,265,213]	-5	hSpCas9	negative selection	1504548
53412045	53412068	X	-	26627737	HeLa	viability after 8 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.8709912151143113	[137]	[75,13,18]	-7	hSpCas9	negative selection	1504549
53412979	53413002	X	-	26627737	HeLa	viability after 8 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.2329923713421524	[655]	[93,34,221]	-8	hSpCas9	negative selection	1504550
53413255	53413278	X	-	26627737	HeLa	viability after 8 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	0.5961312666010858	[135]	[90,136,43]	5	hSpCas9	negative selection	1504551
53415029	53415052	X	+	26627737	HeLa	viability after 8 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-1.2737821784249028	[514]	[145,9,130]	-8	hSpCas9	negative selection	1504552
53409106	53409129	X	-	26627737	HeLa	viability after 12 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-1.011350644038511	[164]	[103,0,1]	-7	hSpCas9	negative selection	1586862
53411779	53411802	X	-	26627737	HeLa	viability after 12 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.5905070895981956	[1035]	[226,362,252]	-5	hSpCas9	negative selection	1586863
53412045	53412068	X	-	26627737	HeLa	viability after 12 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	0.06766820264806506	[137]	[121,41,18]	0	hSpCas9	negative selection	1586864
53412979	53413002	X	-	26627737	HeLa	viability after 12 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.509745347268013	[655]	[87,98,97]	-8	hSpCas9	negative selection	1586865
53413255	53413278	X	-	26627737	HeLa	viability after 12 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	0.11514540783847638	[135]	[77,61,42]	1	hSpCas9	negative selection	1586866
53415029	53415052	X	+	26627737	HeLa	viability after 12 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-1.7392540854929495	[514]	[14,80,91]	-9	hSpCas9	negative selection	1586867
53409106	53409129	X	-	26627737	HeLa	viability after 15 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.312862395977539	[164]	[2,0,0]	-9	hSpCas9	negative selection	1669177
53411779	53411802	X	-	26627737	HeLa	viability after 15 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.554706712770355	[1035]	[269,323,265]	-5	hSpCas9	negative selection	1669178
53412045	53412068	X	-	26627737	HeLa	viability after 15 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	0.38869346313733133	[137]	[79,85,52]	3	hSpCas9	negative selection	1669179
53412979	53413002	X	-	26627737	HeLa	viability after 15 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.6284744285060659	[655]	[272,118,120]	-5	hSpCas9	negative selection	1669180
53413255	53413278	X	-	26627737	HeLa	viability after 15 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.1566892967886209	[135]	[40,11,20]	-7	hSpCas9	negative selection	1669181
53415029	53415052	X	+	26627737	HeLa	viability after 15 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-3.0652340378699563	[514]	[10,6,59]	-9	hSpCas9	negative selection	1669182
53409106	53409129	X	-	26627737	HeLa	viability after 18 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.759583450283944	[164]	[0,0,0]	-9	hSpCas9	negative selection	1751492
53411779	53411802	X	-	26627737	HeLa	viability after 18 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.5510575339257816	[1035]	[177,273,265]	-5	hSpCas9	negative selection	1751493
53412045	53412068	X	-	26627737	HeLa	viability after 18 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	0.3922630590323266	[137]	[50,74,52]	3	hSpCas9	negative selection	1751494
53412979	53413002	X	-	26627737	HeLa	viability after 18 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.6492410517987016	[655]	[177,98,120]	-5	hSpCas9	negative selection	1751495
53413255	53413278	X	-	26627737	HeLa	viability after 18 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.9946690354159893	[135]	[33,8,20]	-7	hSpCas9	negative selection	1751496
53415029	53415052	X	+	26627737	HeLa	viability after 18 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-3.042250968321852	[514]	[7,5,59]	-9	hSpCas9	negative selection	1751497
53409106	53409129	X	-	26627737	HCT116	viability after 6 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	0.2464849594019124	[341]	[173,2]	1	hSpCas9	negative selection	1833807
53411779	53411802	X	-	26627737	HCT116	viability after 6 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.4500319550277454	[1333]	[59,85]	-7	hSpCas9	negative selection	1833808
53412045	53412068	X	-	26627737	HCT116	viability after 6 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-3.7919037643447107	[232]	[1,2]	-9	hSpCas9	negative selection	1833809
53412979	53413002	X	-	26627737	HCT116	viability after 6 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.1837241089612536	[1447]	[91,26]	-8	hSpCas9	negative selection	1833810
53413255	53413278	X	-	26627737	HCT116	viability after 6 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.4587827487521254	[236]	[9,4]	-8	hSpCas9	negative selection	1833811
53415029	53415052	X	+	26627737	HCT116	viability after 6 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-1.466477068846877	[601]	[21,40]	-7	hSpCas9	negative selection	1833812
53409106	53409129	X	-	26627737	HCT116	viability after 8 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-0.6924210402481501	[55]	[0,39,15]	-7	hSpCas9	negative selection	1916122
53411779	53411802	X	-	26627737	HCT116	viability after 8 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.0802655250011222	[608]	[149,169,155]	-8	hSpCas9	negative selection	1916123
53412045	53412068	X	-	26627737	HCT116	viability after 8 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-2.8790962284615835	[178]	[8,5,24]	-9	hSpCas9	negative selection	1916124
53412979	53413002	X	-	26627737	HCT116	viability after 8 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.2500917027275031	[537]	[99,192,80]	-9	hSpCas9	negative selection	1916125
53413255	53413278	X	-	26627737	HCT116	viability after 8 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	1.026499166566999	[43]	[70,64,12]	8	hSpCas9	negative selection	1916126
53415029	53415052	X	+	26627737	HCT116	viability after 8 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-0.17031676821777253	[182]	[81,39,145]	-2	hSpCas9	negative selection	1916127
53409106	53409129	X	-	26627737	HCT116	viability after 9 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-1.9480780847489036	[341]	[2,39]	-8	hSpCas9	negative selection	1998437
53411779	53411802	X	-	26627737	HCT116	viability after 9 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-2.6970851755247534	[1333]	[88,27]	-9	hSpCas9	negative selection	1998438
53412045	53412068	X	-	26627737	HCT116	viability after 9 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-3.6450877428727484	[232]	[9,0]	-9	hSpCas9	negative selection	1998439
53412979	53413002	X	-	26627737	HCT116	viability after 9 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-1.8855704083836728	[1447]	[88,116]	-8	hSpCas9	negative selection	1998440
53413255	53413278	X	-	26627737	HCT116	viability after 9 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	1.0039074803504027	[236]	[60,178]	7	hSpCas9	negative selection	1998441
53415029	53415052	X	+	26627737	HCT116	viability after 9 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-0.5092562672837592	[601]	[165,70]	-4	hSpCas9	negative selection	1998442
53409106	53409129	X	-	26627737	HCT116	viability after 12 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-1.9228197933023763	[55]	[2,19,0]	-9	hSpCas9	negative selection	2080752
53411779	53411802	X	-	26627737	HCT116	viability after 12 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.5644127821781177	[608]	[61,161,105]	-9	hSpCas9	negative selection	2080753
53412045	53412068	X	-	26627737	HCT116	viability after 12 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-1.9189310010092564	[178]	[3,46,25]	-9	hSpCas9	negative selection	2080754
53412979	53413002	X	-	26627737	HCT116	viability after 12 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.13539143019172	[537]	[97,18,71]	-9	hSpCas9	negative selection	2080755
53413255	53413278	X	-	26627737	HCT116	viability after 12 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	1.8399270147771203	[43]	[111,50,81]	9	hSpCas9	negative selection	2080756
53415029	53415052	X	+	26627737	HCT116	viability after 12 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	0.036045772699290435	[182]	[92,85,116]	0	hSpCas9	negative selection	2080757
53409106	53409129	X	-	26627737	HCT116	viability after 15 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-2.5133289202063533	[55]	[5,9,0]	-9	hSpCas9	negative selection	2163067
53411779	53411802	X	-	26627737	HCT116	viability after 15 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-2.098225377891455	[608]	[57,88,94]	-9	hSpCas9	negative selection	2163068
53412045	53412068	X	-	26627737	HCT116	viability after 15 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-3.012513947016031	[178]	[17,19,0]	-9	hSpCas9	negative selection	2163069
53412979	53413002	X	-	26627737	HCT116	viability after 15 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.3400197018225786	[537]	[93,24,67]	-9	hSpCas9	negative selection	2163070
53413255	53413278	X	-	26627737	HCT116	viability after 15 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	0.21944397256927717	[43]	[57,25,7]	2	hSpCas9	negative selection	2163071
53415029	53415052	X	+	26627737	HCT116	viability after 15 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-1.7206917303053797	[182]	[35,14,44]	-9	hSpCas9	negative selection	2163072
53409106	53409129	X	-	26627737	HCT116	viability after 18 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-4.758802546402182	[55]	[0,0,0]	-9	hSpCas9	negative selection	2245382
53411779	53411802	X	-	26627737	HCT116	viability after 18 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-2.589129374354572	[608]	[29,71,42]	-9	hSpCas9	negative selection	2245383
53412045	53412068	X	-	26627737	HCT116	viability after 18 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-3.211290311762635	[178]	[22,3,0]	-9	hSpCas9	negative selection	2245384
53412979	53413002	X	-	26627737	HCT116	viability after 18 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.6165416242193373	[537]	[15,20,93]	-9	hSpCas9	negative selection	2245385
53413255	53413278	X	-	26627737	HCT116	viability after 18 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	1.427710848208722	[43]	[112,22,36]	8	hSpCas9	negative selection	2245386
53415029	53415052	X	+	26627737	HCT116	viability after 18 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-0.6471441833685151	[182]	[74,52,40]	-5	hSpCas9	negative selection	2245387
53415152	53415175	X	-	24336569	HL60	viability	CTTAGGTAAGTCAAATCTCATGG	SMC1A	ENSG00000072501	2.1874027505070526	[143]	[1387]	9	hSpCas9	negative selection	2295843
53422481	53422504	X	+	24336569	HL60	viability	GTTTATCTCACCAGAGCCATTGG	SMC1A	ENSG00000072501	-1.6035059443625048	[414]	[288]	-8	hSpCas9	negative selection	2295844
53422491	53422514	X	-	24336569	HL60	viability	ATCATTGGACCCAATGGCTCTGG	SMC1A	ENSG00000072501	-3.1738146767888678	[886]	[207]	-9	hSpCas9	negative selection	2295845
53422496	53422519	X	+	24336569	HL60	viability	GCCATTGGGTCCAATGATGGCGG	SMC1A	ENSG00000072501	-2.3863186821573175	[125]	[50]	-9	hSpCas9	negative selection	2295846
53422506	53422529	X	-	24336569	HL60	viability	CAGAGGTTCACCGCCATCATTGG	SMC1A	ENSG00000072501	-0.9387756834603864	[403]	[445]	-7	hSpCas9	negative selection	2295847
53422512	53422535	X	+	24336569	HL60	viability	ATGGCGGTGAACCTCTGAAATGG	SMC1A	ENSG00000072501	-1.2979895149333478	[408]	[351]	-8	hSpCas9	negative selection	2295848
53422523	53422546	X	-	24336569	HL60	viability	AGATTATCGGACCATTTCAGAGG	SMC1A	ENSG00000072501	-1.0177385030185093	[309]	[323]	-7	hSpCas9	negative selection	2295849
53422536	53422559	X	-	24336569	HL60	viability	TACAAGGGTCGACAGATTATCGG	SMC1A	ENSG00000072501	-0.08535801673338761	[741]	[1479]	0	hSpCas9	negative selection	2295850
53422551	53422574	X	-	24336569	HL60	viability	GAGAACTTTAAGTCGTACAAGGG	SMC1A	ENSG00000072501	-0.9294610071838463	[170]	[189]	-7	hSpCas9	negative selection	2295851
53422570	53422593	X	+	24336569	HL60	viability	TCTCAATCTCAATCAGTTTCAGG	SMC1A	ENSG00000072501	0.7806337860231399	[180]	[657]	6	hSpCas9	negative selection	2295852
53415152	53415175	X	-	24336569	KBM7	viability	CTTAGGTAAGTCAAATCTCATGG	SMC1A	ENSG00000072501	1.8869078028128494	[182]	[1845]	9	hSpCas9	negative selection	2363020
53422481	53422504	X	+	24336569	KBM7	viability	GTTTATCTCACCAGAGCCATTGG	SMC1A	ENSG00000072501	-4.856511333178539	[392]	[36]	-9	hSpCas9	negative selection	2363021
53422491	53422514	X	-	24336569	KBM7	viability	ATCATTGGACCCAATGGCTCTGG	SMC1A	ENSG00000072501	-2.081451297750985	[359]	[231]	-8	hSpCas9	negative selection	2363022
53422496	53422519	X	+	24336569	KBM7	viability	GCCATTGGGTCCAATGATGGCGG	SMC1A	ENSG00000072501	-6.325323446497885	[146]	[4]	-9	hSpCas9	negative selection	2363023
53422506	53422529	X	-	24336569	KBM7	viability	CAGAGGTTCACCGCCATCATTGG	SMC1A	ENSG00000072501	0.3618701295168484	[294]	[1033]	3	hSpCas9	negative selection	2363024
53422512	53422535	X	+	24336569	KBM7	viability	ATGGCGGTGAACCTCTGAAATGG	SMC1A	ENSG00000072501	-2.5252704810565767	[514]	[243]	-8	hSpCas9	negative selection	2363025
53422523	53422546	X	-	24336569	KBM7	viability	AGATTATCGGACCATTTCAGAGG	SMC1A	ENSG00000072501	-3.9487101064665677	[350]	[61]	-9	hSpCas9	negative selection	2363026
53422536	53422559	X	-	24336569	KBM7	viability	TACAAGGGTCGACAGATTATCGG	SMC1A	ENSG00000072501	0.2817386210666205	[661]	[2194]	2	hSpCas9	negative selection	2363027
53422551	53422574	X	-	24336569	KBM7	viability	GAGAACTTTAAGTCGTACAAGGG	SMC1A	ENSG00000072501	-1.2611660723180016	[57]	[65]	-7	hSpCas9	negative selection	2363028
53422570	53422593	X	+	24336569	KBM7	viability	TCTCAATCTCAATCAGTTTCAGG	SMC1A	ENSG00000072501	0.4072713810471299	[174]	[632]	4	hSpCas9	negative selection	2363029
53417298	53417321	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGTGGCCGAGG	SMC1A	ENSG00000072501	1.9344952843638512	[112,48]	[123,6]	6	dCas9-VP64	positive selection	2393505
53389494	53389517	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCGGATCACAAAG	SMC1A	ENSG00000072501	0.6864243628519979	[21,12]	[10,0]	3	dCas9-VP64	positive selection	2442678
53417298	53417321	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGTGGCCGAGG	SMC1A	ENSG00000072501	2.4580893434569377	[23,25]	[9,77]	9	dCas9-VP64	positive selection	2488760
53389494	53389517	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCGGATCACAAAG	SMC1A	ENSG00000072501	1.29845831928492	[54,84]	[92,21]	7	dCas9-VP64	positive selection	2537933
53409053	53409076	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	0.9573445366011765	[3,2]	[5,6]	9	hSpCas9	positive selection	3022076
53405930	53405953	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-0.3576695159400034	[1,2]	[0,1]	-5	hSpCas9	positive selection	3022077
53409116	53409139	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	-0.35073695807987026	[2,2]	[2,0]	-5	hSpCas9	positive selection	3022078
53414835	53414858	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	-0.6117975852988409	[3,2]	[2,0]	-7	hSpCas9	positive selection	3022079
53409053	53409076	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	-0.16619715642363375	[3,3]	[4,0]	-2	hSpCas9	positive selection	3089934
53405930	53405953	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-0.39498097889923556	[1,1]	[1,0]	-6	hSpCas9	positive selection	3089935
53409116	53409139	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	-0.05376685844982573	[2,2]	[0,2]	0	hSpCas9	positive selection	3089936
53414835	53414858	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	-0.46231195159306027	[3,3]	[1,0]	-6	hSpCas9	positive selection	3089937
53405483	53405506		+	24336571	A375	resistance to PLX after 7 days	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	0.5317719377740603	[14,11]	[21,17]	9	hSpCas9	positive selection	3146136
53405818	53405841		-	24336571	A375	resistance to PLX after 7 days	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	0.005522482666474593	[2,2]	[2,2]	0	hSpCas9	positive selection	3146137
53405507	53405530		+	24336571	A375	resistance to PLX after 7 days	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	0.1635491562070439	[1,1]	[1,1]	5	hSpCas9	positive selection	3146138
53405893	53405916		-	24336571	A375	resistance to PLX after 7 days	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	0.5083002411314004	[3,5]	[6,7]	9	hSpCas9	positive selection	3146139
53405483	53405506		+	24336571	A375	resistance to PLX after 14 days	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	0.2611755799109845	[6,13]	[5,4]	2	hSpCas9	positive selection	3203929
53405818	53405841		-	24336571	A375	resistance to PLX after 14 days	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	1.0233956477404715	[1,1]	[1,1]	7	hSpCas9	positive selection	3203930
53405507	53405530		+	24336571	A375	resistance to PLX after 14 days	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	0.8623214632223537	[1,1]	[1,1]	7	hSpCas9	positive selection	3203931
53405893	53405916		-	24336571	A375	resistance to PLX after 14 days	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	2.6140652498684696	[2,1]	[8,6]	9	hSpCas9	positive selection	3203932
53405483	53405506		+	24336571	A375	viability after 7 days	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.4972030510069919	[19]	[14,11]	-6	hSpCas9	negative selection	3261722
53405818	53405841		-	24336571	A375	viability after 7 days	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	-1.3422898742324494	[8]	[2,2]	-9	hSpCas9	negative selection	3261723
53405507	53405530		+	24336571	A375	viability after 7 days	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.0466896387973672	[4]	[1,1]	-9	hSpCas9	negative selection	3261724
53405893	53405916		-	24336571	A375	viability after 7 days	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.862942201057587	[10]	[3,5]	-8	hSpCas9	negative selection	3261725
53405483	53405506		+	24336571	A375	viability after 14 days	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.8367465681322515	[19]	[6,13]	-8	hSpCas9	negative selection	3319515
53405818	53405841		-	24336571	A375	viability after 14 days	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	-1.8307749289165818	[8]	[1,1]	-9	hSpCas9	negative selection	3319516
53405507	53405530		+	24336571	A375	viability after 14 days	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.0319546132360258	[4]	[1,1]	-8	hSpCas9	negative selection	3319517
53405893	53405916		-	24336571	A375	viability after 14 days	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.7820723290001022	[10]	[2,1]	-9	hSpCas9	negative selection	3319518
53405893	53405916	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	0.5430806937797126	[104,104]	[0,0]	2	hSpCas9	positive selection	3393804
53405929	53405952	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	1.6426163673306269	[48,48]	[0,0]	6	hSpCas9	positive selection	3393805
53396483	53396506	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	3.4499712893882313	[13,13]	[0,0]	9	hSpCas9	positive selection	3393806
53409052	53409075	X	+	26780180	HT29	viability (Avana library 4 designs)	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	2.60196925853393	[]	[]	8	hSpCas9	negative selection	3460652
53405929	53405952	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	4.4606921544574	[]	[]	9	hSpCas9	negative selection	3460653
53409115	53409138	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	5.42972999753105	[]	[]	9	hSpCas9	negative selection	3460654
53414835	53414858	X	-	26780180	HT29	viability (Avana library 4 designs)	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	4.9744332689123	[]	[]	9	hSpCas9	negative selection	3460655
53409052	53409075	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	-1.8355799303012	[]	[]	-2	hSpCas9	negative selection	3561132
53405929	53405952	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-6.79763803902369	[]	[]	-6	hSpCas9	negative selection	3561133
53409115	53409138	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	-13.0946660132355	[]	[]	-8	hSpCas9	negative selection	3561134
53414835	53414858	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	-25.2132370018282	[]	[]	-9	hSpCas9	negative selection	3561135
53405770	53405793	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGCCTCTTGACTACCTGGAGG	SMC1A	ENSG00000072501	-8.1684757761729	[]	[]	-7	hSpCas9	negative selection	3561136
53412045	53412068	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	1.83412885578251	[]	[]	2	hSpCas9	negative selection	3561137
53409052	53409075	X	+	26780180	A375	viability (Avana lentiGuide)	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	5.8167307769499	[]	[]	5	hSpCas9	negative selection	3669791
53405929	53405952	X	+	26780180	A375	viability (Avana lentiGuide)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	17.8267846339814	[]	[]	8	hSpCas9	negative selection	3669792
53409115	53409138	X	+	26780180	A375	viability (Avana lentiGuide)	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	29.4547702963435	[]	[]	9	hSpCas9	negative selection	3669793
53414835	53414858	X	-	26780180	A375	viability (Avana lentiGuide)	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	12.0872386093872	[]	[]	7	hSpCas9	negative selection	3669794
53405770	53405793	X	-	26780180	A375	viability (Avana lentiGuide)	CTTGCCTCTTGACTACCTGGAGG	SMC1A	ENSG00000072501	31.542908914888	[]	[]	9	hSpCas9	negative selection	3669795
53412045	53412068	X	-	26780180	A375	viability (Avana lentiGuide)	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	1.63317159158722	[]	[]	1	hSpCas9	negative selection	3669796
53409052	53409075	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	-0.13246353667924582	[5]	[5,4]	-2	hSpCas9	positive selection	3778398
53405929	53405952	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.2591318632185968	[4]	[2,0]	-9	hSpCas9	positive selection	3778399
53409115	53409138	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	-1.125849742840784	[4]	[2,0]	-9	hSpCas9	positive selection	3778400
53414835	53414858	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	-1.0707664309857816	[7]	[3,2]	-9	hSpCas9	positive selection	3778401
53405770	53405793	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGCCTCTTGACTACCTGGAGG	SMC1A	ENSG00000072501	-1.2047730125405856	[4]	[1,1]	-9	hSpCas9	positive selection	3778402
53412045	53412068	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.5797373086239352	[4]	[2,2]	-7	hSpCas9	positive selection	3778403
53409052	53409075	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCTCTTACCACAGAGCCAGGG	SMC1A	ENSG00000072501	-0.25343847822796506	[5]	[2,4]	-3	hSpCas9	positive selection	3887005
53405929	53405952	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.4334895940839134	[5]	[0,0]	-9	hSpCas9	positive selection	3887006
53409115	53409138	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGCGGCTGCTCTCCTGGCGG	SMC1A	ENSG00000072501	-0.7891111867342709	[5]	[3,0]	-7	hSpCas9	positive selection	3887007
53414835	53414858	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACAAGATCAACAACAAAGTGG	SMC1A	ENSG00000072501	-0.8329666633165197	[5]	[3,1]	-8	hSpCas9	positive selection	3887008
53405770	53405793	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGCCTCTTGACTACCTGGAGG	SMC1A	ENSG00000072501	-1.253120141188124	[4]	[0,1]	-9	hSpCas9	positive selection	3887009
53412045	53412068	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.32300720151353135	[4]	[4,1]	-4	hSpCas9	positive selection	3887010
53396483	53396506	X	-	26780180	A375	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	0.84700668604843	[]	[]	3	hSpCas9	negative selection	3997119
53405483	53405506	X	+	26780180	A375	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	1.69884157313293	[]	[]	9	hSpCas9	negative selection	3997120
53405929	53405952	X	+	26780180	A375	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	2.13443436061596	[]	[]	9	hSpCas9	negative selection	3997121
53405893	53405916	X	-	26780180	A375	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	2.07677503577894	[]	[]	9	hSpCas9	negative selection	3997122
53396522	53396545	X	+	26780180	A375	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.214269999598465	[]	[]	0	hSpCas9	negative selection	3997123
53405537	53405560	X	-	26780180	A375	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	1.53204372917874	[]	[]	8	hSpCas9	negative selection	3997124
53396483	53396506	X	-	26780180	HT29	viability (GeCKOv2 library)	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	1.42263928696621	[]	[]	7	hSpCas9	negative selection	4105085
53405483	53405506	X	+	26780180	HT29	viability (GeCKOv2 library)	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	3.53148066570472	[]	[]	9	hSpCas9	negative selection	4105086
53405929	53405952	X	+	26780180	HT29	viability (GeCKOv2 library)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	2.84496791901027	[]	[]	9	hSpCas9	negative selection	4105087
53405893	53405916	X	-	26780180	HT29	viability (GeCKOv2 library)	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	2.18730204174975	[]	[]	9	hSpCas9	negative selection	4105088
53396522	53396545	X	+	26780180	HT29	viability (GeCKOv2 library)	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.108798580141736	[]	[]	0	hSpCas9	negative selection	4105089
53405537	53405560	X	-	26780180	HT29	viability (GeCKOv2 library)	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	1.50760480896474	[]	[]	7	hSpCas9	negative selection	4105090
53405483	53405506	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.0034283874046556057	[3]	[2,2]	0	hSpCas9	positive selection	4172215
53405818	53405841	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	-0.36075477814028445	[2]	[1,0]	-7	hSpCas9	positive selection	4172216
53405507	53405530	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-0.6573013665558595	[1]	[0,0]	-9	hSpCas9	positive selection	4172217
53405893	53405916	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.03027616275654137	[3]	[1,2]	0	hSpCas9	positive selection	4172218
53405483	53405506	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.3166503557875081	[3]	[0,2,1,0]	-5	hSpCas9	positive selection	4236237
53405818	53405841	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACTGTATTCAGTATATCAAGG	SMC1A	ENSG00000072501	-1.1669573444022907	[4]	[0,0,0,0]	-9	hSpCas9	positive selection	4236238
53405507	53405530	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-0.4165231445267782	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4236239
53405893	53405916	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.9757763325476889	[4]	[0,0,0,0]	-9	hSpCas9	positive selection	4236240
53405483	53405506	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.12091974555912102	[4]	[2,2]	-2	hSpCas9	positive selection	4299270
53396522	53396545	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5441270215298112	[3]	[5,4]	9	hSpCas9	positive selection	4299271
53405537	53405560	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.15629830806766504	[4]	[3,1]	-3	hSpCas9	positive selection	4299272
53405893	53405916	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.6921954165855432	[2]	[1,0]	-9	hSpCas9	positive selection	4363523
53405929	53405952	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-0.7762107725234988	[2]	[0,0]	-9	hSpCas9	positive selection	4363524
53396483	53396506	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.5218930520919874	[1]	[0,0]	-8	hSpCas9	positive selection	4363525
53405807	53405829	X	-	27760321	OCIAML3	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-1.5658551831084946	[424,368]	[134,64]	-8	hSpCas9	negative selection	4441307
53409125	53409147	X	+	27760321	OCIAML3	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-0.5301706125716081	[950,915]	[482,536]	-5	hSpCas9	negative selection	4441308
53409189	53409211	X	+	27760321	OCIAML3	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-0.3435859291317876	[705,680]	[366,507]	-4	hSpCas9	negative selection	4441309
53413255	53413277	X	-	27760321	OCIAML3	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.0270886036334481	[585,450]	[190,205]	-7	hSpCas9	negative selection	4441310
53414749	53414771	X	+	27760321	OCIAML3	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-0.6948507040609002	[642,476]	[232,313]	-6	hSpCas9	negative selection	4441311
53405807	53405829	X	-	27760321	OCIAML2	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-2.9797597224290113	[424,368]	[34,47]	-9	hSpCas9	negative selection	4524770
53409125	53409147	X	+	27760321	OCIAML2	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-1.5741996405708263	[950,915]	[225,290]	-8	hSpCas9	negative selection	4524771
53409189	53409211	X	+	27760321	OCIAML2	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-0.12658126349495713	[705,680]	[478,561]	-2	hSpCas9	negative selection	4524772
53413255	53413277	X	-	27760321	OCIAML2	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.546451390390993	[585,450]	[126,162]	-8	hSpCas9	negative selection	4524773
53414749	53414771	X	+	27760321	OCIAML2	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-1.760866074924142	[642,476]	[144,115]	-9	hSpCas9	negative selection	4524774
53405807	53405829	X	-	27760321	MV411	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-2.790421509079856	[424,368]	[4,86]	-9	hSpCas9	negative selection	4608233
53409125	53409147	X	+	27760321	MV411	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-0.38375809350536094	[950,915]	[187,900]	-3	hSpCas9	negative selection	4608234
53409189	53409211	X	+	27760321	MV411	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	0.550079187942016	[705,680]	[757,540]	4	hSpCas9	negative selection	4608235
53413255	53413277	X	-	27760321	MV411	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.3733024472238413	[585,450]	[7,315]	-7	hSpCas9	negative selection	4608236
53414749	53414771	X	+	27760321	MV411	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-0.8903636442745939	[642,476]	[185,214]	-5	hSpCas9	negative selection	4608237
53405807	53405829	X	-	27760321	HL60	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-2.2913454310559325	[424,368]	[101,27]	-9	hSpCas9	negative selection	4691696
53409125	53409147	X	+	27760321	HL60	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-0.6031348144609656	[950,915]	[498,506]	-6	hSpCas9	negative selection	4691697
53409189	53409211	X	+	27760321	HL60	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-0.49920570748581206	[705,680]	[335,470]	-5	hSpCas9	negative selection	4691698
53413255	53413277	X	-	27760321	HL60	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.018661597549569	[585,450]	[78,129]	-9	hSpCas9	negative selection	4691699
53414749	53414771	X	+	27760321	HL60	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-0.6862719983825587	[642,476]	[306,254]	-6	hSpCas9	negative selection	4691700
53405807	53405829	X	-	27760321	HT1080	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-7.031935282497242	[368,287]	[0,0]	-9	hSpCas9	negative selection	4775159
53409125	53409147	X	+	27760321	HT1080	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-3.598374898517202	[915,714]	[1,53]	-7	hSpCas9	negative selection	4775160
53409189	53409211	X	+	27760321	HT1080	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-4.3928509785867895	[680,531]	[0,22]	-8	hSpCas9	negative selection	4775161
53413255	53413277	X	-	27760321	HT1080	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-4.916493218036967	[450,351]	[0,9]	-8	hSpCas9	negative selection	4775162
53414749	53414771	X	+	27760321	HT1080	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-3.361460838911794	[476,371]	[25,5]	-7	hSpCas9	negative selection	4775163
53405807	53405829	X	-	27760321	HT29	viability after 7 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-1.7462341798643617	[368,287]	[113,141,119]	-9	hSpCas9	negative selection	4858622
53409125	53409147	X	+	27760321	HT29	viability after 7 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-0.6706231307830106	[915,714]	[842,707,456]	-7	hSpCas9	negative selection	4858623
53409189	53409211	X	+	27760321	HT29	viability after 7 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-0.2947698082013345	[680,531]	[752,471,695]	-4	hSpCas9	negative selection	4858624
53413255	53413277	X	-	27760321	HT29	viability after 7 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.9130950026478295	[450,351]	[487,169,196]	-8	hSpCas9	negative selection	4858625
53414749	53414771	X	+	27760321	HT29	viability after 7 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	0.4786839982710407	[476,371]	[771,652,853]	7	hSpCas9	negative selection	4858626
53405807	53405829	X	-	27760321	HT29	viability after 25 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-5.260791665107012	[368,287]	[0,26,0]	-9	hSpCas9	negative selection	4942085
53409125	53409147	X	+	27760321	HT29	viability after 25 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-3.5885335467648	[915,714]	[105,59,62]	-9	hSpCas9	negative selection	4942086
53409189	53409211	X	+	27760321	HT29	viability after 25 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-1.6419252672954705	[680,531]	[226,187,253]	-7	hSpCas9	negative selection	4942087
53413255	53413277	X	-	27760321	HT29	viability after 25 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-3.9625269470082234	[450,351]	[1,66,19]	-9	hSpCas9	negative selection	4942088
53414749	53414771	X	+	27760321	HT29	viability after 25 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-2.1592952677552897	[476,371]	[133,29,165]	-8	hSpCas9	negative selection	4942089
53405807	53405829	X	-	27760321	HT29	viability after 22 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-7.835330453632339	[368,287]	[0,2,0]	-9	hSpCas9	negative selection	5025548
53409125	53409147	X	+	27760321	HT29	viability after 22 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-3.304747055340683	[915,714]	[105,76,102]	-9	hSpCas9	negative selection	5025549
53409189	53409211	X	+	27760321	HT29	viability after 22 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-2.002173171316792	[680,531]	[123,171,230]	-8	hSpCas9	negative selection	5025550
53413255	53413277	X	-	27760321	HT29	viability after 22 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-4.820364648585843	[450,351]	[0,0,47]	-9	hSpCas9	negative selection	5025551
53414749	53414771	X	+	27760321	HT29	viability after 22 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-1.5774397850789892	[476,371]	[175,148,167]	-7	hSpCas9	negative selection	5025552
53405807	53405829	X	-	27760321	HT29	viability after 19 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-7.13710284938059	[368,287]	[1,4,0]	-9	hSpCas9	negative selection	5109011
53409125	53409147	X	+	27760321	HT29	viability after 19 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-3.2373979929887167	[915,714]	[15,120,148]	-9	hSpCas9	negative selection	5109012
53409189	53409211	X	+	27760321	HT29	viability after 19 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-1.1927595052545	[680,531]	[344,117,445]	-7	hSpCas9	negative selection	5109013
53413255	53413277	X	-	27760321	HT29	viability after 19 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-3.3453404917966543	[450,351]	[50,9,73]	-9	hSpCas9	negative selection	5109014
53414749	53414771	X	+	27760321	HT29	viability after 19 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-2.773979631290011	[476,371]	[55,75,78]	-8	hSpCas9	negative selection	5109015
53405807	53405829	X	-	27760321	HT29	viability after 16 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-6.384882755196046	[368,287]	[11,0,0]	-9	hSpCas9	negative selection	5192474
53409125	53409147	X	+	27760321	HT29	viability after 16 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-4.331769475805682	[915,714]	[18,61,51]	-9	hSpCas9	negative selection	5192475
53409189	53409211	X	+	27760321	HT29	viability after 16 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-1.125494345551517	[680,531]	[276,380,269]	-7	hSpCas9	negative selection	5192476
53413255	53413277	X	-	27760321	HT29	viability after 16 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.8972037120410454	[450,351]	[22,73,79]	-9	hSpCas9	negative selection	5192477
53414749	53414771	X	+	27760321	HT29	viability after 16 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-1.726579871766425	[476,371]	[162,155,112]	-8	hSpCas9	negative selection	5192478
53405807	53405829	X	-	27760321	HT29	viability after 13 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-7.3313384452334525	[368,287]	[0,1,3]	-9	hSpCas9	negative selection	5275937
53409125	53409147	X	+	27760321	HT29	viability after 13 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-2.8052081587453976	[915,714]	[53,229,122]	-9	hSpCas9	negative selection	5275938
53409189	53409211	X	+	27760321	HT29	viability after 13 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-1.0740156321424306	[680,531]	[230,456,315]	-7	hSpCas9	negative selection	5275939
53413255	53413277	X	-	27760321	HT29	viability after 13 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-3.1184857545026317	[450,351]	[0,20,133]	-9	hSpCas9	negative selection	5275940
53414749	53414771	X	+	27760321	HT29	viability after 13 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-1.0312276669529292	[476,371]	[284,235,203]	-7	hSpCas9	negative selection	5275941
53405807	53405829	X	-	27760321	HT29	viability after 10 days	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-3.582293021695829	[368,287]	[82,17,1]	-9	hSpCas9	negative selection	5359400
53409125	53409147	X	+	27760321	HT29	viability after 10 days	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-2.509405072660507	[915,714]	[131,270,136]	-9	hSpCas9	negative selection	5359401
53409189	53409211	X	+	27760321	HT29	viability after 10 days	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-0.2507456355714208	[680,531]	[504,768,638]	-3	hSpCas9	negative selection	5359402
53413255	53413277	X	-	27760321	HT29	viability after 10 days	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.6669784144436774	[450,351]	[101,92,42]	-9	hSpCas9	negative selection	5359403
53414749	53414771	X	+	27760321	HT29	viability after 10 days	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-0.6859447642990986	[476,371]	[233,426,329]	-7	hSpCas9	negative selection	5359404
53405807	53405829	X	-	27760321	MOLM13	viability	GTATATCAAGGAGCAGCGTGGG	SMC1A	ENSG00000072501	-0.46676218712547834	[424,368]	[71,237]	-3	hSpCas9	negative selection	5442863
53409125	53409147	X	+	27760321	MOLM13	viability	GCTCTCCTGGCGGTCGATGCGG	SMC1A	ENSG00000072501	-1.3974326482246173	[950,915]	[209,191]	-7	hSpCas9	negative selection	5442864
53409189	53409211	X	+	27760321	MOLM13	viability	ATTTCATCAATACGCCGCTTGG	SMC1A	ENSG00000072501	-1.3255431233652564	[705,680]	[29,263]	-6	hSpCas9	negative selection	5442865
53413255	53413277	X	-	27760321	MOLM13	viability	AATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	1.2515421772817148	[585,450]	[161,1141]	8	hSpCas9	negative selection	5442866
53414749	53414771	X	+	27760321	MOLM13	viability	AACGCCCACCTGGAAAACGAGG	SMC1A	ENSG00000072501	-1.324937808109229	[642,476]	[3,227]	-6	hSpCas9	negative selection	5442867
53422610	53422633	X	+	27661255	K562	viability	GGCGCCGGCGGCAGTAGGACAGG	SMC1A	ENSG00000072501	-2.2318644465083812	[448,371]	[82,58]	-9	dCas9-KRAB	negative selection	5512862
53405483	53405506	X	+	27260156	BXPC3	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.7302046198293206	[1005]	[719,478,672,663]	-9	hSpCas9	negative selection	5571730
53396522	53396545	X	+	27260156	BXPC3	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5418266616433612	[931]	[1223,1388,1593,1492]	9	hSpCas9	negative selection	5571731
53405537	53405560	X	-	27260156	BXPC3	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.1227782631232421	[1057]	[479,534,388,639]	-9	hSpCas9	negative selection	5571732
53405893	53405916	X	-	27260156	BXPC3	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.3300752150695556	[409]	[193,164,116,205]	-9	hSpCas9	negative selection	5635983
53405929	53405952	X	+	27260156	BXPC3	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.777952496449511	[422]	[114,151,109,138]	-9	hSpCas9	negative selection	5635984
53396483	53396506	X	-	27260156	BXPC3	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.0084906823713453	[83]	[40,18,44,74]	-9	hSpCas9	negative selection	5635985
53405483	53405506	X	+	27260156	A673	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.45566546911315464	[1005]	[1028,821,862,822]	-8	hSpCas9	negative selection	5692981
53396522	53396545	X	+	27260156	A673	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.4566393232669811	[931]	[1569,1362,1694,1517]	8	hSpCas9	negative selection	5692982
53405537	53405560	X	-	27260156	A673	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.4388109069965165	[1057]	[1118,898,975,764]	-8	hSpCas9	negative selection	5692983
53405893	53405916	X	-	27260156	A673	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.9081032214405589	[409]	[309,256,280,202]	-9	hSpCas9	negative selection	5757234
53405929	53405952	X	+	27260156	A673	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.001967106320249	[422]	[307,195,272,243]	-9	hSpCas9	negative selection	5757235
53396483	53396506	X	-	27260156	A673	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.5880479217317411	[83]	[81,63,29,95]	-8	hSpCas9	negative selection	5757236
53405483	53405506	X	+	27260156	A375	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6064499383899539	[1005]	[686,971,890,583]	-7	hSpCas9	negative selection	5814232
53396522	53396545	X	+	27260156	A375	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7212915598249644	[931]	[1859,2152,1700,1538]	9	hSpCas9	negative selection	5814233
53405537	53405560	X	-	27260156	A375	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.2982219678298992	[1057]	[546,625,511,357]	-9	hSpCas9	negative selection	5814234
53405893	53405916	X	-	27260156	A375	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.3031380454515433	[409]	[96,166,164,325]	-9	hSpCas9	negative selection	5878485
53405929	53405952	X	+	27260156	A375	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.841297918043778	[422]	[196,158,121,82]	-9	hSpCas9	negative selection	5878486
53396483	53396506	X	-	27260156	A375	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.4467127658626886	[83]	[18,31,63,28]	-9	hSpCas9	negative selection	5878487
53405483	53405506	X	+	27260156	COLO741	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.49073279719650775	[1005]	[1006,913,834]	-8	hSpCas9	negative selection	5935483
53396522	53396545	X	+	27260156	COLO741	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.4667182900286774	[931]	[1782,1826,1356]	8	hSpCas9	negative selection	5935484
53405537	53405560	X	-	27260156	COLO741	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.5917381978871494	[1057]	[1075,789,841]	-8	hSpCas9	negative selection	5935485
53405893	53405916	X	-	27260156	COLO741	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.518278190938697	[409]	[486,232,384]	-8	hSpCas9	negative selection	5999736
53405929	53405952	X	+	27260156	COLO741	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.5849582610177746	[422]	[208,146,185]	-9	hSpCas9	negative selection	5999737
53396483	53396506	X	-	27260156	COLO741	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.3854946229885083	[83]	[68,8,46]	-9	hSpCas9	negative selection	5999738
53405483	53405506	X	+	27260156	CAL120	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-1.1481648097445396	[1005]	[574,678,443]	-9	hSpCas9	negative selection	6056734
53396522	53396545	X	+	27260156	CAL120	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7143572465455469	[931]	[2063,1813,1854]	9	hSpCas9	negative selection	6056735
53405537	53405560	X	-	27260156	CAL120	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.815994680051378	[1057]	[1045,547,694]	-8	hSpCas9	negative selection	6056736
53405893	53405916	X	-	27260156	CAL120	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.0483378290345884	[409]	[185,138,402]	-8	hSpCas9	negative selection	6120987
53405929	53405952	X	+	27260156	CAL120	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.3508534828154772	[422]	[23,80,190]	-9	hSpCas9	negative selection	6120988
53396483	53396506	X	-	27260156	CAL120	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.285102570133832	[83]	[9,86,26]	-9	hSpCas9	negative selection	6120989
53405483	53405506	X	+	27260156	CADOES1	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.742797641247454	[1005]	[435,642,673,480]	-8	hSpCas9	negative selection	6177985
53396522	53396545	X	+	27260156	CADOES1	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5254825561144686	[931]	[1222,1023,1402,1343]	8	hSpCas9	negative selection	6177986
53405537	53405560	X	-	27260156	CADOES1	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.7792818152391345	[1057]	[508,570,626,586]	-8	hSpCas9	negative selection	6177987
53405893	53405916	X	-	27260156	CADOES1	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.8397867662015794	[409]	[129,279,243,197]	-9	hSpCas9	negative selection	6242238
53405929	53405952	X	+	27260156	CADOES1	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.8368034416779189	[422]	[157,51,101,128]	-9	hSpCas9	negative selection	6242239
53396483	53396506	X	-	27260156	CADOES1	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.2249895148351215	[83]	[58,29,26,16]	-9	hSpCas9	negative selection	6242240
53405483	53405506	X	+	27260156	EWS502	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.596236813768813	[1005]	[572,769,766,721]	-7	hSpCas9	negative selection	6299236
53396522	53396545	X	+	27260156	EWS502	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7690829375606706	[931]	[1316,1699,1536,2250]	9	hSpCas9	negative selection	6299237
53405537	53405560	X	-	27260156	EWS502	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.8416212048974466	[1057]	[568,607,680,650]	-8	hSpCas9	negative selection	6299238
53405893	53405916	X	-	27260156	EWS502	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.670238547832378	[409]	[137,125,154,125]	-9	hSpCas9	negative selection	6363489
53405929	53405952	X	+	27260156	EWS502	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.8986207911564175	[422]	[216,62,102,84]	-9	hSpCas9	negative selection	6363490
53396483	53396506	X	-	27260156	EWS502	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.4016464544984899	[83]	[49,56,50,116]	-6	hSpCas9	negative selection	6363491
53405483	53405506	X	+	27260156	EW8	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.8263617029440722	[1005]	[449,573,372,454]	-9	hSpCas9	negative selection	6420487
53396522	53396545	X	+	27260156	EW8	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7355037180666774	[931]	[1489,1135,1244,1182]	9	hSpCas9	negative selection	6420488
53405537	53405560	X	-	27260156	EW8	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.6953232418685911	[1057]	[617,516,483,514]	-8	hSpCas9	negative selection	6420489
53405893	53405916	X	-	27260156	EW8	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.8073894054673514	[409]	[134,165,258,180]	-8	hSpCas9	negative selection	6484740
53405929	53405952	X	+	27260156	EW8	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.2069310824010586	[422]	[188,119,93,203]	-9	hSpCas9	negative selection	6484741
53396483	53396506	X	-	27260156	EW8	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.4136229146030388	[83]	[24,46,20,9]	-9	hSpCas9	negative selection	6484742
53405483	53405506	X	+	27260156	CORL105	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.4991313010370183	[1005]	[774,752,1065,774]	-7	hSpCas9	negative selection	6541738
53396522	53396545	X	+	27260156	CORL105	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.6147364665213492	[931]	[1857,1582,1714,1541]	9	hSpCas9	negative selection	6541739
53405537	53405560	X	-	27260156	CORL105	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.1176139736500807	[1057]	[633,539,514,587]	-9	hSpCas9	negative selection	6541740
53405893	53405916	X	-	27260156	CORL105	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.302260570519809	[409]	[143,162,175,290]	-9	hSpCas9	negative selection	6605991
53405929	53405952	X	+	27260156	CORL105	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.1631278996677887	[422]	[196,197,171,308]	-9	hSpCas9	negative selection	6605992
53396483	53396506	X	-	27260156	CORL105	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.5943980704856346	[83]	[52,52,44,105]	-8	hSpCas9	negative selection	6605993
53405483	53405506	X	+	27260156	HS294T	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.4647088227441335	[1005]	[206,275,263,407]	-6	hSpCas9	negative selection	6662989
53396522	53396545	X	+	27260156	HS294T	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.32093204550057963	[931]	[403,377,463,581]	4	hSpCas9	negative selection	6662990
53405537	53405560	X	-	27260156	HS294T	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.8383497246447364	[1057]	[154,154,285,347]	-8	hSpCas9	negative selection	6662991
53405893	53405916	X	-	27260156	HS294T	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.13217401012268812	[409]	[67,288,111,104]	-2	hSpCas9	negative selection	6727242
53405929	53405952	X	+	27260156	HS294T	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.0749845942197784	[422]	[26,23,55,51]	-9	hSpCas9	negative selection	6727243
53396483	53396506	X	-	27260156	HS294T	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.9531772334513846	[83]	[18,7,18,21]	-8	hSpCas9	negative selection	6727244
53405483	53405506	X	+	27260156	HCC44	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.8018955734606756	[1005]	[595,619,888,543]	-8	hSpCas9	negative selection	6784240
53396522	53396545	X	+	27260156	HCC44	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7157078852199158	[931]	[1749,1168,2471,1728]	9	hSpCas9	negative selection	6784241
53405537	53405560	X	-	27260156	HCC44	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.416787597729387	[1057]	[532,475,435,348]	-9	hSpCas9	negative selection	6784242
53405893	53405916	X	-	27260156	HCC44	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.4714194292306317	[409]	[177,106,145,239]	-9	hSpCas9	negative selection	6848493
53405929	53405952	X	+	27260156	HCC44	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-3.195277036873762	[422]	[74,61,15,49]	-9	hSpCas9	negative selection	6848494
53396483	53396506	X	-	27260156	HCC44	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.5993658825788124	[83]	[4,16,68,39]	-9	hSpCas9	negative selection	6848495
53405483	53405506	X	+	27260156	G402	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.5739128769380205	[1005]	[788,1169,880,486]	-6	hSpCas9	negative selection	6905491
53396522	53396545	X	+	27260156	G402	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.9644440327139524	[931]	[3001,2110,1737,2127]	9	hSpCas9	negative selection	6905492
53405537	53405560	X	-	27260156	G402	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.19577960011744044	[1057]	[2028,751,605,1220]	-2	hSpCas9	negative selection	6905493
53405893	53405916	X	-	27260156	G402	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.7666560839322677	[409]	[524,419,87,187]	-7	hSpCas9	negative selection	6969744
53405929	53405952	X	+	27260156	G402	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-0.8480782739103735	[422]	[132,756,144,123]	-7	hSpCas9	negative selection	6969745
53396483	53396506	X	-	27260156	G402	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.4634641365005261	[83]	[100,26,134,36]	-5	hSpCas9	negative selection	6969746
53405483	53405506	X	+	27260156	L33	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.07587119890365268	[1005]	[1039,357,575,984]	-2	hSpCas9	negative selection	7026742
53396522	53396545	X	+	27260156	L33	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5270469519463338	[931]	[1482,566,733,1332]	9	hSpCas9	negative selection	7026743
53405537	53405560	X	-	27260156	L33	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.2977512620738102	[1057]	[830,277,558,1042]	-6	hSpCas9	negative selection	7026744
53405893	53405916	X	-	27260156	L33	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.5218680983013638	[409]	[232,102,163,396]	-8	hSpCas9	negative selection	7090995
53405929	53405952	X	+	27260156	L33	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.1235539307803515	[422]	[238,51,146,175]	-9	hSpCas9	negative selection	7090996
53396483	53396506	X	-	27260156	L33	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	0.12820981664743236	[83]	[46,35,53,146]	3	hSpCas9	negative selection	7090997
53405483	53405506	X	+	27260156	K562	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6323784912407644	[1005]	[765,613,477,472]	-6	hSpCas9	negative selection	7147993
53396522	53396545	X	+	27260156	K562	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.6969172377368583	[931]	[1093,1412,1645,1203]	8	hSpCas9	negative selection	7147994
53405537	53405560	X	-	27260156	K562	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.5035670410051457	[1057]	[503,628,821,674]	-6	hSpCas9	negative selection	7147995
53405893	53405916	X	-	27260156	K562	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.4494657731803093	[409]	[151,9,152,203]	-9	hSpCas9	negative selection	7212246
53405929	53405952	X	+	27260156	K562	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.6271817378991917	[422]	[132,22,60,32]	-9	hSpCas9	negative selection	7212247
53396483	53396506	X	-	27260156	K562	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-2.2325075051279546	[83]	[5,2,37,14]	-9	hSpCas9	negative selection	7212248
53405483	53405506	X	+	27260156	HT29	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-1.0823112145982883	[1005]	[676,533,692,424]	-9	hSpCas9	negative selection	7269244
53396522	53396545	X	+	27260156	HT29	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.6345075034797872	[931]	[1726,1921,1626,1757]	9	hSpCas9	negative selection	7269245
53405537	53405560	X	-	27260156	HT29	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.0077882438578978	[1057]	[733,675,441,703]	-8	hSpCas9	negative selection	7269246
53405893	53405916	X	-	27260156	HT29	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.7162970064691245	[409]	[164,122,162,152]	-9	hSpCas9	negative selection	7333497
53405929	53405952	X	+	27260156	HT29	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.6044835683415095	[422]	[95,137,59,52]	-9	hSpCas9	negative selection	7333498
53396483	53396506	X	-	27260156	HT29	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.4211641361737217	[83]	[54,35,38,24]	-9	hSpCas9	negative selection	7333499
53405483	53405506	X	+	27260156	MHHES1	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.7538859211547024	[1005]	[639,638,759,634]	-8	hSpCas9	negative selection	7390495
53396522	53396545	X	+	27260156	MHHES1	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.9351248644049795	[931]	[2402,2746,1652,1434]	9	hSpCas9	negative selection	7390496
53405537	53405560	X	-	27260156	MHHES1	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.7300738798304958	[1057]	[642,562,1059,596]	-8	hSpCas9	negative selection	7390497
53405893	53405916	X	-	27260156	MHHES1	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.8099750389361364	[409]	[252,291,321,197]	-9	hSpCas9	negative selection	7454748
53405929	53405952	X	+	27260156	MHHES1	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.5234043567382756	[422]	[153,190,234,96]	-9	hSpCas9	negative selection	7454749
53396483	53396506	X	-	27260156	MHHES1	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.6579382942472778	[83]	[117,49,65,19]	-8	hSpCas9	negative selection	7454750
53405483	53405506	X	+	27260156	MEWO	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.5868436275816403	[1005]	[667,579,639]	-8	hSpCas9	negative selection	7511746
53396522	53396545	X	+	27260156	MEWO	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.4706388996207532	[931]	[1386,1038,1233]	8	hSpCas9	negative selection	7511747
53405537	53405560	X	-	27260156	MEWO	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.6021228920815584	[1057]	[741,552,678]	-8	hSpCas9	negative selection	7511748
53405893	53405916	X	-	27260156	MEWO	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.140286411703137	[409]	[183,163,175]	-9	hSpCas9	negative selection	7575999
53405929	53405952	X	+	27260156	MEWO	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.3288845777036156	[422]	[66,79,86]	-9	hSpCas9	negative selection	7576000
53396483	53396506	X	-	27260156	MEWO	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.8372124330015889	[83]	[38,40,50]	-9	hSpCas9	negative selection	7576001
53405483	53405506	X	+	27260156	LNCAPCLONEFGC	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6962738458335612	[1005]	[598,555,548,542]	-8	hSpCas9	negative selection	7632997
53396522	53396545	X	+	27260156	LNCAPCLONEFGC	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7153035743124562	[931]	[1145,1423,1387,1587]	9	hSpCas9	negative selection	7632998
53405537	53405560	X	-	27260156	LNCAPCLONEFGC	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.9718566957197843	[1057]	[462,449,533,516]	-8	hSpCas9	negative selection	7632999
53405893	53405916	X	-	27260156	LNCAPCLONEFGC	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.3094728980551034	[409]	[150,104,154,191]	-9	hSpCas9	negative selection	7697250
53405929	53405952	X	+	27260156	LNCAPCLONEFGC	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.0516765864408146	[422]	[89,94,88,94]	-9	hSpCas9	negative selection	7697251
53396483	53396506	X	-	27260156	LNCAPCLONEFGC	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.1172645801104695	[83]	[54,35,15,29]	-9	hSpCas9	negative selection	7697252
53405483	53405506	X	+	27260156	PANC0327	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.2793776191572319	[1005]	[599,802,652,868]	-4	hSpCas9	negative selection	7754248
53396522	53396545	X	+	27260156	PANC0327	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5395467053055029	[931]	[1370,1039,1231,1204]	7	hSpCas9	negative selection	7754249
53405537	53405560	X	-	27260156	PANC0327	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.5560305675550922	[1057]	[608,462,677,826]	-7	hSpCas9	negative selection	7754250
53405893	53405916	X	-	27260156	PANC0327	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.2036949034753244	[409]	[260,39,111,242]	-9	hSpCas9	negative selection	7818501
53405929	53405952	X	+	27260156	PANC0327	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.7448868725902755	[422]	[139,30,62,226]	-9	hSpCas9	negative selection	7818502
53396483	53396506	X	-	27260156	PANC0327	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.03922246421508779	[83]	[10,167,24,68]	0	hSpCas9	negative selection	7818503
53405483	53405506	X	+	27260156	NCIH2009	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-1.0066300208082686	[1005]	[1088,447,641]	-8	hSpCas9	negative selection	7875499
53396522	53396545	X	+	27260156	NCIH2009	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7078417397952567	[931]	[2957,1812,1775]	8	hSpCas9	negative selection	7875500
53405537	53405560	X	-	27260156	NCIH2009	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-2.0069659030931595	[1057]	[472,283,367]	-9	hSpCas9	negative selection	7875501
53405893	53405916	X	-	27260156	NCIH2009	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-2.0883392651770873	[409]	[167,104,137]	-9	hSpCas9	negative selection	7939752
53405929	53405952	X	+	27260156	NCIH2009	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.2554232875765994	[422]	[106,222,35]	-9	hSpCas9	negative selection	7939753
53396483	53396506	X	-	27260156	NCIH2009	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.9894429484213862	[83]	[126,39,23]	-8	hSpCas9	negative selection	7939754
53405483	53405506	X	+	27260156	NCIH1373	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.3300147218928481	[1005]	[1341,631,1276,102]	-3	hSpCas9	negative selection	7996750
53396522	53396545	X	+	27260156	NCIH1373	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	1.2257949862719486	[931]	[2089,2570,2586,640]	9	hSpCas9	negative selection	7996751
53405537	53405560	X	-	27260156	NCIH1373	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.6937950127878456	[1057]	[351,451,340,79]	-9	hSpCas9	negative selection	7996752
53405893	53405916	X	-	27260156	NCIH1373	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.3054215775029683	[409]	[140,75,340,48]	-8	hSpCas9	negative selection	8061003
53405929	53405952	X	+	27260156	NCIH1373	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.870551171732033	[422]	[59,34,107,14]	-9	hSpCas9	negative selection	8061004
53396483	53396506	X	-	27260156	NCIH1373	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.3721610860061122	[83]	[138,3,5,3]	-8	hSpCas9	negative selection	8061005
53405483	53405506	X	+	27260156	PATU8902	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-1.2581417206877183	[1005]	[1039,581,440,268]	-8	hSpCas9	negative selection	8118001
53396522	53396545	X	+	27260156	PATU8902	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	1.1147225518218433	[931]	[3009,3270,2132,3004]	9	hSpCas9	negative selection	8118002
53405537	53405560	X	-	27260156	PATU8902	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.5232968827928985	[1057]	[191,323,593,973]	-8	hSpCas9	negative selection	8118003
53405893	53405916	X	-	27260156	PATU8902	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-3.316431475860204	[409]	[140,12,47,23]	-9	hSpCas9	negative selection	8182254
53405929	53405952	X	+	27260156	PATU8902	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-4.389753504233103	[422]	[18,48,8,41]	-9	hSpCas9	negative selection	8182255
53396483	53396506	X	-	27260156	PATU8902	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.2225121389311315	[83]	[8,46,118,1]	-8	hSpCas9	negative selection	8182256
53405483	53405506	X	+	27260156	PANC1	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.7569479835674192	[1005]	[497,763,662,214]	-8	hSpCas9	negative selection	8239252
53396522	53396545	X	+	27260156	PANC1	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7049072137863538	[931]	[1111,1771,1450,1012]	9	hSpCas9	negative selection	8239253
53405537	53405560	X	-	27260156	PANC1	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.2420700994308211	[1057]	[432,494,299,331]	-9	hSpCas9	negative selection	8239254
53405893	53405916	X	-	27260156	PANC1	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-2.7242059666566525	[409]	[66,39,40,59]	-9	hSpCas9	negative selection	8303505
53405929	53405952	X	+	27260156	PANC1	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.8642239874000164	[422]	[25,40,95,36]	-9	hSpCas9	negative selection	8303506
53396483	53396506	X	-	27260156	PANC1	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.4263015222027011	[83]	[12,35,18,38]	-9	hSpCas9	negative selection	8303507
53405483	53405506	X	+	27260156	PANC0813	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.8135479354795656	[1005]	[889,736,645,447]	-8	hSpCas9	negative selection	8360503
53396522	53396545	X	+	27260156	PANC0813	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5667931770292355	[931]	[1845,1599,1580,1484]	8	hSpCas9	negative selection	8360504
53405537	53405560	X	-	27260156	PANC0813	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.6437293011640042	[1057]	[715,367,266,274]	-9	hSpCas9	negative selection	8360505
53405893	53405916	X	-	27260156	PANC0813	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.9393255970296337	[409]	[205,102,86,113]	-9	hSpCas9	negative selection	8424756
53405929	53405952	X	+	27260156	PANC0813	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.0745522166980215	[422]	[112,88,144,123]	-9	hSpCas9	negative selection	8424757
53396483	53396506	X	-	27260156	PANC0813	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.8301997447484877	[83]	[38,28,86,64]	-8	hSpCas9	negative selection	8424758
53405483	53405506	X	+	27260156	RDES	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.805969530271835	[1005]	[551,629,646,852]	-8	hSpCas9	negative selection	8481754
53396522	53396545	X	+	27260156	RDES	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7108444866697335	[931]	[1293,1888,1826,2096]	9	hSpCas9	negative selection	8481755
53405537	53405560	X	-	27260156	RDES	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.4121804882541182	[1057]	[382,345,565,567]	-9	hSpCas9	negative selection	8481756
53405893	53405916	X	-	27260156	RDES	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.1533147157529036	[409]	[155,190,251,266]	-9	hSpCas9	negative selection	8546007
53405929	53405952	X	+	27260156	RDES	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.164667167798247	[422]	[119,87,103,118]	-9	hSpCas9	negative selection	8546008
53396483	53396506	X	-	27260156	RDES	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.03316269513589498	[83]	[16,72,211,97]	0	hSpCas9	negative selection	8546009
53405483	53405506	X	+	27260156	PC3	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.2688497155697108	[1005]	[571,816,1182,923]	-6	hSpCas9	negative selection	8603005
53396522	53396545	X	+	27260156	PC3	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.3697219954880332	[931]	[829,1036,2211,1159]	7	hSpCas9	negative selection	8603006
53405537	53405560	X	-	27260156	PC3	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.2152040096372564	[1057]	[596,893,1748,759]	-5	hSpCas9	negative selection	8603007
53405893	53405916	X	-	27260156	PC3	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.8932186439252401	[409]	[152,224,427,157]	-9	hSpCas9	negative selection	8667258
53405929	53405952	X	+	27260156	PC3	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.2091545606438237	[422]	[92,179,360,189]	-9	hSpCas9	negative selection	8667259
53396483	53396506	X	-	27260156	PC3	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.580601377396659	[83]	[37,31,4,135]	-8	hSpCas9	negative selection	8667260
53405483	53405506	X	+	27260156	PATU8988T	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6897759746395113	[1005]	[354,553,830,667]	-8	hSpCas9	negative selection	8724256
53396522	53396545	X	+	27260156	PATU8988T	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.6215837749576495	[931]	[1222,1285,1677,1337]	8	hSpCas9	negative selection	8724257
53405537	53405560	X	-	27260156	PATU8988T	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.7662513930337715	[1057]	[572,671,597,564]	-8	hSpCas9	negative selection	8724258
53405893	53405916	X	-	27260156	PATU8988T	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.48818268656222	[409]	[97,336,57,86]	-9	hSpCas9	negative selection	8788509
53405929	53405952	X	+	27260156	PATU8988T	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.0124361989853763	[422]	[55,182,94,76]	-9	hSpCas9	negative selection	8788510
53396483	53396506	X	-	27260156	PATU8988T	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.2969293051519375	[83]	[180,23,42,7]	-5	hSpCas9	negative selection	8788511
53405483	53405506	X	+	27260156	T47D	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6108316824192785	[1005]	[913,657,842,659]	-8	hSpCas9	negative selection	8845507
53396522	53396545	X	+	27260156	T47D	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5385530309274814	[931]	[1742,1495,1455,1623]	9	hSpCas9	negative selection	8845508
53405537	53405560	X	-	27260156	T47D	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.9639370846331838	[1057]	[665,658,549,651]	-9	hSpCas9	negative selection	8845509
53405893	53405916	X	-	27260156	T47D	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.2394668298968077	[409]	[252,176,217,161]	-9	hSpCas9	negative selection	8909760
53405929	53405952	X	+	27260156	T47D	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.6580572298822192	[422]	[152,194,152,118]	-9	hSpCas9	negative selection	8909761
53396483	53396506	X	-	27260156	T47D	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.4075573909454189	[83]	[92,31,66,107]	-7	hSpCas9	negative selection	8909762
53405483	53405506	X	+	27260156	SU8686	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-1.12239738261784	[1005]	[356,432,486,588]	-8	hSpCas9	negative selection	8966758
53396522	53396545	X	+	27260156	SU8686	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.7449483812512171	[931]	[1359,1229,1686,2054]	9	hSpCas9	negative selection	8966759
53405537	53405560	X	-	27260156	SU8686	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-1.8513509201467593	[1057]	[337,189,369,268]	-9	hSpCas9	negative selection	8966760
53405893	53405916	X	-	27260156	SU8686	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.62214851340749	[409]	[62,142,212,113]	-9	hSpCas9	negative selection	9031011
53405929	53405952	X	+	27260156	SU8686	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-2.700875839290356	[422]	[52,71,61,71]	-9	hSpCas9	negative selection	9031012
53396483	53396506	X	-	27260156	SU8686	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.9041467277982149	[83]	[43,47,22,64]	-8	hSpCas9	negative selection	9031013
53405483	53405506	X	+	27260156	SKES1	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6035477560834154	[1005]	[684,678,699,584]	-8	hSpCas9	negative selection	9088009
53396522	53396545	X	+	27260156	SKES1	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.3959832649468701	[931]	[1206,1598,995,1134]	7	hSpCas9	negative selection	9088010
53405537	53405560	X	-	27260156	SKES1	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.8317534378142187	[1057]	[686,597,622,483]	-9	hSpCas9	negative selection	9088011
53405893	53405916	X	-	27260156	SKES1	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-1.2330865844097083	[409]	[169,231,112,184]	-9	hSpCas9	negative selection	9152262
53405929	53405952	X	+	27260156	SKES1	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.3819633471082144	[422]	[96,188,152,196]	-9	hSpCas9	negative selection	9152263
53396483	53396506	X	-	27260156	SKES1	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-1.0512805456328405	[83]	[53,31,22,51]	-9	hSpCas9	negative selection	9152264
53405483	53405506	X	+	27260156	TOV112D	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.44160767088019637	[1005]	[703,996,695,631]	-7	hSpCas9	negative selection	9209260
53396522	53396545	X	+	27260156	TOV112D	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.5028813735212257	[931]	[1286,1815,1049,1255]	8	hSpCas9	negative selection	9209261
53405537	53405560	X	-	27260156	TOV112D	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.47490608655759425	[1057]	[812,1081,678,562]	-7	hSpCas9	negative selection	9209262
53405893	53405916	X	-	27260156	TOV112D	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.8898894678379667	[409]	[277,309,191,134]	-9	hSpCas9	negative selection	9273513
53405929	53405952	X	+	27260156	TOV112D	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-0.6320167932767544	[422]	[240,172,355,294]	-8	hSpCas9	negative selection	9273514
53396483	53396506	X	-	27260156	TOV112D	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	0.0589892964260601	[83]	[20,147,78,110]	1	hSpCas9	negative selection	9273515
53405483	53405506	X	+	27260156	TC71	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.2846503563450298	[1005]	[818,897,806,1029]	-6	hSpCas9	negative selection	9330511
53396522	53396545	X	+	27260156	TC71	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.4810232533014761	[931]	[1305,1411,1356,1512]	9	hSpCas9	negative selection	9330512
53405537	53405560	X	-	27260156	TC71	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.32866509568039526	[1057]	[950,821,745,1109]	-7	hSpCas9	negative selection	9330513
53405893	53405916	X	-	27260156	TC71	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.6027330344817774	[409]	[311,276,203,371]	-9	hSpCas9	negative selection	9394764
53405929	53405952	X	+	27260156	TC71	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.0235096931980197	[422]	[280,167,248,189]	-9	hSpCas9	negative selection	9394765
53396483	53396506	X	-	27260156	TC71	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.8211035124181083	[83]	[72,47,11,72]	-9	hSpCas9	negative selection	9394766
53405483	53405506	X	+	27260156	TC32	viability	GAATCCACACCTTGTGGCGCTGG	SMC1A	ENSG00000072501	-0.6348950436053543	[1005]	[507,314,973,804]	-8	hSpCas9	negative selection	9451762
53396522	53396545	X	+	27260156	TC32	viability	GTCATTCACTTCCGACTTCTTGG	SMC1A	ENSG00000072501	0.8874451957780632	[931]	[1721,1093,2156,1694]	9	hSpCas9	negative selection	9451763
53405537	53405560	X	-	27260156	TC32	viability	TGCCCTTGTCTGTGACAACGTGG	SMC1A	ENSG00000072501	-0.6414241334959556	[1057]	[680,518,726,636]	-8	hSpCas9	negative selection	9451764
53405893	53405916	X	-	27260156	TC32	viability	GTATCAGATTGCTGTAACCAAGG	SMC1A	ENSG00000072501	-0.7682143904973576	[409]	[193,144,328,279]	-9	hSpCas9	negative selection	9516015
53405929	53405952	X	+	27260156	TC32	viability	GCTGGCATAGGTCAATGAGGCGG	SMC1A	ENSG00000072501	-1.0146536428464112	[422]	[188,165,231,206]	-9	hSpCas9	negative selection	9516016
53396483	53396506	X	-	27260156	TC32	viability	AGGAGATTCGTAAGAAACTCGGG	SMC1A	ENSG00000072501	-0.3701823108257396	[83]	[56,75,40,56]	-6	hSpCas9	negative selection	9516017
53409106	53409129	X	-	27869803	HPAFII	viability after 27 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.320347059067882	[75]	[0,0,NaN]	-9	hSpCas9	negative selection	9609138
53411779	53411802	X	-	27869803	HPAFII	viability after 27 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.06232719917948337	[517]	[82,408,NaN]	0	hSpCas9	negative selection	9609139
53412045	53412068	X	-	27869803	HPAFII	viability after 27 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	1.4896735426509857	[78]	[240,12,NaN]	9	hSpCas9	negative selection	9609140
53412979	53413002	X	-	27869803	HPAFII	viability after 27 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.5802915193193466	[317]	[77,139,NaN]	-4	hSpCas9	negative selection	9609141
53413255	53413278	X	-	27869803	HPAFII	viability after 27 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.411292240140261	[108]	[14,26,NaN]	-7	hSpCas9	negative selection	9609142
53415029	53415052	X	+	27869803	HPAFII	viability after 27 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-6.744844887595792	[203]	[0,0,NaN]	-9	hSpCas9	negative selection	9609143
53409106	53409129	X	-	27869803	HPAFII	viability after 15 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-3.770767768535479	[75]	[13,0,NaN]	-9	hSpCas9	negative selection	9691587
53411779	53411802	X	-	27869803	HPAFII	viability after 15 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.5027343717668141	[517]	[477,339,NaN]	-5	hSpCas9	negative selection	9691588
53412045	53412068	X	-	27869803	HPAFII	viability after 15 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	1.3255178555752303	[78]	[435,73,NaN]	9	hSpCas9	negative selection	9691589
53412979	53413002	X	-	27869803	HPAFII	viability after 15 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.9182370493367984	[317]	[141,204,NaN]	-7	hSpCas9	negative selection	9691590
53413255	53413278	X	-	27869803	HPAFII	viability after 15 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.3939356749177516	[108]	[127,64,NaN]	-4	hSpCas9	negative selection	9691591
53415029	53415052	X	+	27869803	HPAFII	viability after 15 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-3.7583518500751296	[203]	[30,6,NaN]	-9	hSpCas9	negative selection	9691592
53409106	53409129	X	-	27869803	ASPC1	viability after 36 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-4.515460881186019	[223]	[0,0,6]	-9	hSpCas9	negative selection	9774036
53411779	53411802	X	-	27869803	ASPC1	viability after 36 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.623077872060365	[1013]	[286,335,102]	-6	hSpCas9	negative selection	9774037
53412045	53412068	X	-	27869803	ASPC1	viability after 36 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.8090340498222834	[246]	[13,21,94]	-7	hSpCas9	negative selection	9774038
53412979	53413002	X	-	27869803	ASPC1	viability after 36 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-2.8021427256801212	[874]	[5,30,79]	-9	hSpCas9	negative selection	9774039
53413255	53413278	X	-	27869803	ASPC1	viability after 36 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.0833657423342351	[285]	[162,97,41]	-1	hSpCas9	negative selection	9774040
53415029	53415052	X	+	27869803	ASPC1	viability after 36 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-0.8002488586659173	[613]	[179,103,96]	-7	hSpCas9	negative selection	9774041
53409106	53409129	X	-	27869803	PATU8988S	viability after 35 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.270949278120832	[239]	[3,0,NaN]	-9	hSpCas9	negative selection	9856485
53411779	53411802	X	-	27869803	PATU8988S	viability after 35 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-0.6535285853278361	[1020]	[223,298,NaN]	-6	hSpCas9	negative selection	9856486
53412045	53412068	X	-	27869803	PATU8988S	viability after 35 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	0.19603516841826907	[219]	[101,100,NaN]	2	hSpCas9	negative selection	9856487
53412979	53413002	X	-	27869803	PATU8988S	viability after 35 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.7207649188910374	[686]	[118,216,NaN]	-6	hSpCas9	negative selection	9856488
53413255	53413278	X	-	27869803	PATU8988S	viability after 35 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.1207705798718486	[242]	[46,42,NaN]	-8	hSpCas9	negative selection	9856489
53415029	53415052	X	+	27869803	PATU8988S	viability after 35 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-4.26171474213823	[524]	[20,0,NaN]	-9	hSpCas9	negative selection	9856490
53409106	53409129	X	-	27869803	PATU8988S	viability after 31 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.496235694941037	[239]	[2,0,NaN]	-9	hSpCas9	negative selection	9938934
53411779	53411802	X	-	27869803	PATU8988S	viability after 31 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	-1.2283696011358565	[1020]	[160,189,NaN]	-8	hSpCas9	negative selection	9938935
53412045	53412068	X	-	27869803	PATU8988S	viability after 31 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	-0.3076356708077721	[219]	[58,85,NaN]	-3	hSpCas9	negative selection	9938936
53412979	53413002	X	-	27869803	PATU8988S	viability after 31 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.2868141983216933	[686]	[169,293,NaN]	-3	hSpCas9	negative selection	9938937
53413255	53413278	X	-	27869803	PATU8988S	viability after 31 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-0.5742673102585483	[242]	[50,82,NaN]	-6	hSpCas9	negative selection	9938938
53415029	53415052	X	+	27869803	PATU8988S	viability after 31 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-4.477184880277889	[524]	[4,14,NaN]	-9	hSpCas9	negative selection	9938939
53409106	53409129	X	-	27869803	HPAFII	viability after 35 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.265838960446911	[75]	[0,0,NaN]	-9	hSpCas9	negative selection	10021383
53411779	53411802	X	-	27869803	HPAFII	viability after 35 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	0.10051807995762285	[517]	[124,456,NaN]	0	hSpCas9	negative selection	10021384
53412045	53412068	X	-	27869803	HPAFII	viability after 35 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	2.0847439113715858	[78]	[298,23,NaN]	9	hSpCas9	negative selection	10021385
53412979	53413002	X	-	27869803	HPAFII	viability after 35 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	-0.17807869087759104	[317]	[19,279,NaN]	-1	hSpCas9	negative selection	10021386
53413255	53413278	X	-	27869803	HPAFII	viability after 35 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-1.5031813372434604	[108]	[10,28,NaN]	-7	hSpCas9	negative selection	10021387
53415029	53415052	X	+	27869803	HPAFII	viability after 35 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-6.690336788974821	[203]	[0,0,NaN]	-9	hSpCas9	negative selection	10021388
53409106	53409129	X	-	27869803	HPAFII	viability after 31 days	GAGCAGCCGCCAGCAGCGAAAGG	SMC1A	ENSG00000072501	-5.414556313768328	[75]	[0,0,NaN]	-9	hSpCas9	negative selection	10103832
53411779	53411802	X	-	27869803	HPAFII	viability after 31 days	ACCGTCTGGATCTGGAAGAACGG	SMC1A	ENSG00000072501	0.10463798069799268	[517]	[157,480,NaN]	0	hSpCas9	negative selection	10103833
53412045	53412068	X	-	27869803	HPAFII	viability after 31 days	GCAGGAGTTTGAAGAACGGATGG	SMC1A	ENSG00000072501	1.8311519696584055	[78]	[263,41,NaN]	9	hSpCas9	negative selection	10103834
53412979	53413002	X	-	27869803	HPAFII	viability after 31 days	GGACAAGAAGCGTATGGACAAGG	SMC1A	ENSG00000072501	0.09115717325878442	[317]	[24,369,NaN]	0	hSpCas9	negative selection	10103835
53413255	53413278	X	-	27869803	HPAFII	viability after 31 days	AAATATTGCGGCTGAACGCAAGG	SMC1A	ENSG00000072501	-2.0875320186313053	[108]	[11,16,NaN]	-8	hSpCas9	negative selection	10103836
53415029	53415052	X	+	27869803	HPAFII	viability after 31 days	AGACCATGCTGACAAAGGCCCGG	SMC1A	ENSG00000072501	-6.839054142296238	[203]	[0,0,NaN]	-9	hSpCas9	negative selection	10103837
53409440	53409463	X	-	28162770	P31FUJ	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-7.362085221359345	[279]	[1]	-9	hSpCas9	negative selection	10238922
53405253	53405276	X	-	28162770	P31FUJ	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-4.182487739763683	[478]	[30]	-9	hSpCas9	negative selection	10238923
53413327	53413350	X	-	28162770	P31FUJ	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-5.139692800022897	[29]	[0]	-9	hSpCas9	negative selection	10238924
53413027	53413050	X	-	28162770	P31FUJ	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.868569075807026	[288]	[185]	-6	hSpCas9	negative selection	10238925
53413000	53413023	X	-	28162770	P31FUJ	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-2.2999164002729158	[87]	[20]	-8	hSpCas9	negative selection	10238926
53412973	53412996	X	-	28162770	P31FUJ	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-0.9790456121685955	[51]	[30]	-6	hSpCas9	negative selection	10238927
53412907	53412930	X	-	28162770	P31FUJ	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.9876897065778474	[80]	[11]	-9	hSpCas9	negative selection	10238928
53409480	53409503	X	-	28162770	P31FUJ	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.9354692781754201	[96]	[217]	9	hSpCas9	negative selection	10238929
53409163	53409186	X	-	28162770	P31FUJ	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-3.6746397630369376	[488]	[44]	-9	hSpCas9	negative selection	10238930
53405507	53405530	X	+	28162770	P31FUJ	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-3.2563377188751677	[308]	[37]	-9	hSpCas9	negative selection	10238931
53409440	53409463	X	-	28162770	TF1	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10408288
53405253	53405276	X	-	28162770	TF1	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10408289
53413327	53413350	X	-	28162770	TF1	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10408290
53413027	53413050	X	-	28162770	TF1	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10408291
53413000	53413023	X	-	28162770	TF1	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10408292
53412973	53412996	X	-	28162770	TF1	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10408293
53412907	53412930	X	-	28162770	TF1	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10408294
53409480	53409503	X	-	28162770	TF1	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10408295
53409163	53409186	X	-	28162770	TF1	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10408296
53405507	53405530	X	+	28162770	TF1	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10408297
53409440	53409463	X	-	28162770	SKM1	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-4.712772628267247	[88]	[5]	-9	hSpCas9	negative selection	10577654
53405253	53405276	X	-	28162770	SKM1	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-3.4189368404092377	[120]	[19]	-9	hSpCas9	negative selection	10577655
53413327	53413350	X	-	28162770	SKM1	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.6293566200796095	[13]	[0]	-9	hSpCas9	negative selection	10577656
53413027	53413050	X	-	28162770	SKM1	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.3231958410505638	[91]	[64]	-7	hSpCas9	negative selection	10577657
53413000	53413023	X	-	28162770	SKM1	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-0.92153737157292	[14]	[13]	-6	hSpCas9	negative selection	10577658
53412973	53412996	X	-	28162770	SKM1	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-0.9795429750084854	[28]	[25]	-6	hSpCas9	negative selection	10577659
53412907	53412930	X	-	28162770	SKM1	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-3.406964198743162	[17]	[2]	-9	hSpCas9	negative selection	10577660
53409480	53409503	X	-	28162770	SKM1	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-1.5382087320214144	[22]	[13]	-7	hSpCas9	negative selection	10577661
53409163	53409186	X	-	28162770	SKM1	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.7561137623655485	[106]	[27]	-9	hSpCas9	negative selection	10577662
53405507	53405530	X	+	28162770	SKM1	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.7065244806020698	[71]	[38]	-8	hSpCas9	negative selection	10577663
53409440	53409463	X	-	28162770	SKM1	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-4.712772628267247	[88]	[5]	-9	hSpCas9	negative selection	10747020
53405253	53405276	X	-	28162770	SKM1	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-3.4189368404092377	[120]	[19]	-9	hSpCas9	negative selection	10747021
53413327	53413350	X	-	28162770	SKM1	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.6293566200796095	[13]	[0]	-9	hSpCas9	negative selection	10747022
53413027	53413050	X	-	28162770	SKM1	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.3231958410505638	[91]	[64]	-7	hSpCas9	negative selection	10747023
53413000	53413023	X	-	28162770	SKM1	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-0.92153737157292	[14]	[13]	-6	hSpCas9	negative selection	10747024
53412973	53412996	X	-	28162770	SKM1	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-0.9795429750084854	[28]	[25]	-6	hSpCas9	negative selection	10747025
53412907	53412930	X	-	28162770	SKM1	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-3.406964198743162	[17]	[2]	-9	hSpCas9	negative selection	10747026
53409480	53409503	X	-	28162770	SKM1	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-1.5382087320214144	[22]	[13]	-7	hSpCas9	negative selection	10747027
53409163	53409186	X	-	28162770	SKM1	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.7561137623655485	[106]	[27]	-9	hSpCas9	negative selection	10747028
53405507	53405530	X	+	28162770	SKM1	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.7065244806020698	[71]	[38]	-8	hSpCas9	negative selection	10747029
53409440	53409463	X	-	28162770	PL21	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-1.4350960927130596	[291]	[46]	-7	hSpCas9	negative selection	10916386
53405253	53405276	X	-	28162770	PL21	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-2.2027084757816096	[274]	[25]	-8	hSpCas9	negative selection	10916387
53413327	53413350	X	-	28162770	PL21	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-3.3848228862318366	[23]	[0]	-9	hSpCas9	negative selection	10916388
53413027	53413050	X	-	28162770	PL21	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.694973813342845	[304]	[40]	-8	hSpCas9	negative selection	10916389
53413000	53413023	X	-	28162770	PL21	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-1.5841316944552428	[61]	[8]	-7	hSpCas9	negative selection	10916390
53412973	53412996	X	-	28162770	PL21	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-0.2762984294536668	[63]	[22]	-2	hSpCas9	negative selection	10916391
53412907	53412930	X	-	28162770	PL21	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.424351250418473	[73]	[5]	-9	hSpCas9	negative selection	10916392
53409480	53409503	X	-	28162770	PL21	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.6777185798368769	[78]	[54]	6	hSpCas9	negative selection	10916393
53409163	53409186	X	-	28162770	PL21	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-1.4099138671946663	[347]	[56]	-7	hSpCas9	negative selection	10916394
53405507	53405530	X	+	28162770	PL21	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.2730320607742796	[210]	[37]	-7	hSpCas9	negative selection	10916395
53409440	53409463	X	-	28162770	P31FUJ	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-7.362085221359345	[279]	[1]	-9	hSpCas9	negative selection	11085752
53405253	53405276	X	-	28162770	P31FUJ	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-4.182487739763683	[478]	[30]	-9	hSpCas9	negative selection	11085753
53413327	53413350	X	-	28162770	P31FUJ	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-5.139692800022897	[29]	[0]	-9	hSpCas9	negative selection	11085754
53413027	53413050	X	-	28162770	P31FUJ	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.868569075807026	[288]	[185]	-6	hSpCas9	negative selection	11085755
53413000	53413023	X	-	28162770	P31FUJ	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-2.2999164002729158	[87]	[20]	-8	hSpCas9	negative selection	11085756
53412973	53412996	X	-	28162770	P31FUJ	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-0.9790456121685955	[51]	[30]	-6	hSpCas9	negative selection	11085757
53412907	53412930	X	-	28162770	P31FUJ	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.9876897065778474	[80]	[11]	-9	hSpCas9	negative selection	11085758
53409480	53409503	X	-	28162770	P31FUJ	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.9354692781754201	[96]	[217]	9	hSpCas9	negative selection	11085759
53409163	53409186	X	-	28162770	P31FUJ	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-3.6746397630369376	[488]	[44]	-9	hSpCas9	negative selection	11085760
53405507	53405530	X	+	28162770	P31FUJ	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-3.2563377188751677	[308]	[37]	-9	hSpCas9	negative selection	11085761
53409440	53409463	X	-	28162770	OCIAML5	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-1.7913125397849008	[185]	[96]	-7	hSpCas9	negative selection	11255118
53405253	53405276	X	-	28162770	OCIAML5	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-5.647925854083772	[249]	[8]	-9	hSpCas9	negative selection	11255119
53413327	53413350	X	-	28162770	OCIAML5	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.659421492921601	[13]	[0]	-9	hSpCas9	negative selection	11255120
53413027	53413050	X	-	28162770	OCIAML5	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-5.357594604090748	[158]	[6]	-9	hSpCas9	negative selection	11255121
53413000	53413023	X	-	28162770	OCIAML5	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-6.91815576132177	[66]	[0]	-9	hSpCas9	negative selection	11255122
53412973	53412996	X	-	28162770	OCIAML5	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.8964606902224503	[65]	[31]	-7	hSpCas9	negative selection	11255123
53412907	53412930	X	-	28162770	OCIAML5	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-4.684956585028739	[56]	[3]	-9	hSpCas9	negative selection	11255124
53409480	53409503	X	-	28162770	OCIAML5	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-0.93223691954798	[36]	[34]	-5	hSpCas9	negative selection	11255125
53409163	53409186	X	-	28162770	OCIAML5	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.8735462982744484	[202]	[49]	-8	hSpCas9	negative selection	11255126
53405507	53405530	X	+	28162770	OCIAML5	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-4.142743731766919	[136]	[13]	-9	hSpCas9	negative selection	11255127
53409440	53409463	X	-	28162770	EOL1	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-1.7888052653737212	[504]	[76]	-8	hSpCas9	negative selection	11424484
53405253	53405276	X	-	28162770	EOL1	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-3.2560244740712863	[543]	[29]	-9	hSpCas9	negative selection	11424485
53413327	53413350	X	-	28162770	EOL1	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.006189565992352	[60]	[1]	-9	hSpCas9	negative selection	11424486
53413027	53413050	X	-	28162770	EOL1	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.691441624771246	[563]	[91]	-8	hSpCas9	negative selection	11424487
53413000	53413023	X	-	28162770	EOL1	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-0.6002937367130508	[140]	[48]	-4	hSpCas9	negative selection	11424488
53412973	53412996	X	-	28162770	EOL1	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-2.2222936167587366	[185]	[20]	-8	hSpCas9	negative selection	11424489
53412907	53412930	X	-	28162770	EOL1	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.047437852259869	[101]	[12]	-8	hSpCas9	negative selection	11424490
53409480	53409503	X	-	28162770	EOL1	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-0.39738032331682804	[59]	[23]	-3	hSpCas9	negative selection	11424491
53409163	53409186	X	-	28162770	EOL1	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.4277539723603465	[479]	[46]	-8	hSpCas9	negative selection	11424492
53405507	53405530	X	+	28162770	EOL1	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-2.02298480853533	[269]	[34]	-8	hSpCas9	negative selection	11424493
53409440	53409463	X	-	28162770	MOLM13	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-5.283176409666481	[376]	[6]	-9	hSpCas9	negative selection	11593850
53405253	53405276	X	-	28162770	MOLM13	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-4.246356136121544	[524]	[19]	-9	hSpCas9	negative selection	11593851
53413327	53413350	X	-	28162770	MOLM13	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-5.43900121406394	[59]	[0]	-9	hSpCas9	negative selection	11593852
53413027	53413050	X	-	28162770	MOLM13	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-3.874926079816607	[486]	[23]	-9	hSpCas9	negative selection	11593853
53413000	53413023	X	-	28162770	MOLM13	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-6.260031073018621	[105]	[0]	-9	hSpCas9	negative selection	11593854
53412973	53412996	X	-	28162770	MOLM13	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-6.462847956018308	[121]	[0]	-9	hSpCas9	negative selection	11593855
53412907	53412930	X	-	28162770	MOLM13	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-6.246356136121545	[104]	[0]	-9	hSpCas9	negative selection	11593856
53409480	53409503	X	-	28162770	MOLM13	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-1.8988929491270437	[97]	[18]	-7	hSpCas9	negative selection	11593857
53409163	53409186	X	-	28162770	MOLM13	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-3.5093905419553377	[503]	[31]	-8	hSpCas9	negative selection	11593858
53405507	53405530	X	+	28162770	MOLM13	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-1.2965569490437343	[264]	[77]	-6	hSpCas9	negative selection	11593859
53409440	53409463	X	-	28162770	HEL	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-4.0827048922706295	[290]	[10]	-9	hSpCas9	negative selection	11763216
53405253	53405276	X	-	28162770	HEL	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-4.115114128639672	[486]	[17]	-9	hSpCas9	negative selection	11763217
53413327	53413350	X	-	28162770	HEL	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-5.1646160900572475	[55]	[0]	-9	hSpCas9	negative selection	11763218
53413027	53413050	X	-	28162770	HEL	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.9237510086493204	[387]	[130]	-5	hSpCas9	negative selection	11763219
53413000	53413023	X	-	28162770	HEL	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-1.8845081708645117	[97]	[16]	-7	hSpCas9	negative selection	11763220
53412973	53412996	X	-	28162770	HEL	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.8865142361345115	[126]	[21]	-7	hSpCas9	negative selection	11763221
53412907	53412930	X	-	28162770	HEL	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-6.264151763608162	[119]	[0]	-9	hSpCas9	negative selection	11763222
53409480	53409503	X	-	28162770	HEL	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-2.566714533628593	[73]	[7]	-8	hSpCas9	negative selection	11763223
53409163	53409186	X	-	28162770	HEL	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-3.5850670855224553	[355]	[18]	-9	hSpCas9	negative selection	11763224
53405507	53405530	X	+	28162770	HEL	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-4.738082951940574	[249]	[5]	-9	hSpCas9	negative selection	11763225
53409440	53409463	X	-	28162770	MV411	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-3.260357089415921	[272]	[23]	-9	hSpCas9	negative selection	11932582
53405253	53405276	X	-	28162770	MV411	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-6.00048996266081	[303]	[3]	-9	hSpCas9	negative selection	11932583
53413327	53413350	X	-	28162770	MV411	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.39641863899195	[24]	[0]	-9	hSpCas9	negative selection	11932584
53413027	53413050	X	-	28162770	MV411	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-0.9164485341781968	[297]	[132]	-6	hSpCas9	negative selection	11932585
53413000	53413023	X	-	28162770	MV411	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	0.4345231033832704	[64]	[73]	4	hSpCas9	negative selection	11932586
53412973	53412996	X	-	28162770	MV411	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.2379892763874665	[69]	[24]	-7	hSpCas9	negative selection	11932587
53412907	53412930	X	-	28162770	MV411	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-5.861086905995394	[68]	[0]	-9	hSpCas9	negative selection	11932588
53409480	53409503	X	-	28162770	MV411	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	0.10304764144760048	[62]	[56]	0	hSpCas9	negative selection	11932589
53409163	53409186	X	-	28162770	MV411	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-1.6125864397877692	[264]	[72]	-7	hSpCas9	negative selection	11932590
53405507	53405530	X	+	28162770	MV411	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-2.9604553008585572	[230]	[24]	-9	hSpCas9	negative selection	11932591
53409440	53409463	X	-	28162770	MONOMAC1	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-1.6363218925850749	[159]	[58]	-8	hSpCas9	negative selection	12101948
53405253	53405276	X	-	28162770	MONOMAC1	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-3.758915734667669	[247]	[20]	-9	hSpCas9	negative selection	12101949
53413327	53413350	X	-	28162770	MONOMAC1	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-2.1039274426680725	[14]	[3]	-9	hSpCas9	negative selection	12101950
53413027	53413050	X	-	28162770	MONOMAC1	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-2.4986925469206547	[211]	[42]	-9	hSpCas9	negative selection	12101951
53413000	53413023	X	-	28162770	MONOMAC1	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-2.78199934778071	[41]	[6]	-9	hSpCas9	negative selection	12101952
53412973	53412996	X	-	28162770	MONOMAC1	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-2.263126037517326	[66]	[15]	-9	hSpCas9	negative selection	12101953
53412907	53412930	X	-	28162770	MONOMAC1	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-2.8600018597819834	[18]	[2]	-9	hSpCas9	negative selection	12101954
53409480	53409503	X	-	28162770	MONOMAC1	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-1.2811011118480282	[52]	[24]	-7	hSpCas9	negative selection	12101955
53409163	53409186	X	-	28162770	MONOMAC1	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.0669763064951807	[211]	[57]	-9	hSpCas9	negative selection	12101956
53405507	53405530	X	+	28162770	MONOMAC1	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-4.047893407753744	[100]	[6]	-9	hSpCas9	negative selection	12101957
53409440	53409463	X	-	28162770	OCIAML2	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-5.545917952546398	[58]	[6]	-9	hSpCas9	negative selection	12271314
53405253	53405276	X	-	28162770	OCIAML2	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-2.29005757960034	[59]	[67]	-8	hSpCas9	negative selection	12271315
53413327	53413350	X	-	28162770	OCIAML2	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-2.0555923259633175	[2]	[3]	-8	hSpCas9	negative selection	12271316
53413027	53413050	X	-	28162770	OCIAML2	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.6383572709802277	[81]	[145]	-7	hSpCas9	negative selection	12271317
53413000	53413023	X	-	28162770	OCIAML2	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-1.4200037521721933	[13]	[28]	-7	hSpCas9	negative selection	12271318
53412973	53412996	X	-	28162770	OCIAML2	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-1.16577524371374	[16]	[41]	-6	hSpCas9	negative selection	12271319
53412907	53412930	X	-	28162770	OCIAML2	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-6.171069543383254	[12]	[0]	-9	hSpCas9	negative selection	12271320
53409480	53409503	X	-	28162770	OCIAML2	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-0.2742326124386578	[11]	[54]	-2	hSpCas9	negative selection	12271321
53409163	53409186	X	-	28162770	OCIAML2	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.3551526078222254	[59]	[64]	-8	hSpCas9	negative selection	12271322
53405507	53405530	X	+	28162770	OCIAML2	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-3.3286108203697333	[28]	[15]	-9	hSpCas9	negative selection	12271323
53409440	53409463	X	-	28162770	OCIAML3	viability	GAAGCGGATTGAGAAACTGGAGG	SMC1A	ENSG00000072501	-3.2686073535299958	[82]	[25]	-9	hSpCas9	negative selection	12440680
53405253	53405276	X	-	28162770	OCIAML3	viability	GAAGAAGGAGCGCTTGACAGAGG	SMC1A	ENSG00000072501	-1.9223335064096763	[112]	[89]	-8	hSpCas9	negative selection	12440681
53413327	53413350	X	-	28162770	OCIAML3	viability	GGAGTATGACAAGCGAAAGAAGG	SMC1A	ENSG00000072501	-4.763932641766475	[8]	[0]	-9	hSpCas9	negative selection	12440682
53413027	53413050	X	-	28162770	OCIAML3	viability	TGAGAAGCTCAACAAGGAACTGG	SMC1A	ENSG00000072501	-1.3309732344903695	[84]	[101]	-7	hSpCas9	negative selection	12440683
53413000	53413023	X	-	28162770	OCIAML3	viability	AAAGAACAAGGAGATCGAGAAGG	SMC1A	ENSG00000072501	-2.382503535130451	[18]	[10]	-9	hSpCas9	negative selection	12440684
53412973	53412996	X	-	28162770	OCIAML3	viability	GAAGCGTATGGACAAGGTGGAGG	SMC1A	ENSG00000072501	-4.272079545436801	[31]	[4]	-9	hSpCas9	negative selection	12440685
53412907	53412930	X	-	28162770	OCIAML3	viability	GGAGCAGCAGCAGATTGAGAAGG	SMC1A	ENSG00000072501	-0.09150729979497996	[5]	[16]	0	hSpCas9	negative selection	12440686
53409480	53409503	X	-	28162770	OCIAML3	viability	CCAAGATCAAGCAAAAGCTGCGG	SMC1A	ENSG00000072501	-1.1300605405643729	[28]	[39]	-7	hSpCas9	negative selection	12440687
53409163	53409186	X	-	28162770	OCIAML3	viability	TAAGGAGCTGAACCAGGTGATGG	SMC1A	ENSG00000072501	-2.1633732859943007	[91]	[61]	-8	hSpCas9	negative selection	12440688
53405507	53405530	X	+	28162770	OCIAML3	viability	GGCCTCCAAAGGCAATGCGGCGG	SMC1A	ENSG00000072501	-2.487092436407651	[64]	[34]	-9	hSpCas9	negative selection	12440689