Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9126
• Symbol: SMC3
• Description: structural maintenance of chromosomes 3

DataSource: http://genomecrispr.dkfz.de/#!/results/SMC3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
110583463	110583486	10	+	26472758	Jiyoye	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-2.363342772371359	[231]	[33]	-8	hSpCas9	negative selection	151805
110578641	110578664	10	+	26472758	Jiyoye	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.19854567938208012	[34]	[22]	-1	hSpCas9	negative selection	151806
110582621	110582644	10	+	26472758	Jiyoye	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.100619258692824	[181]	[0]	-9	hSpCas9	negative selection	151807
110601028	110601051	10	+	26472758	Jiyoye	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	151808
110601759	110601782	10	+	26472758	Jiyoye	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.4378499585177855	[96]	[26]	-7	hSpCas9	negative selection	151809
110582023	110582046	10	+	26472758	Jiyoye	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-6.615192431522582	[129]	[0]	-9	hSpCas9	negative selection	151810
110583488	110583511	10	+	26472758	Jiyoye	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-1.5928246184941273	[3]	[0]	-8	hSpCas9	negative selection	151811
110583931	110583954	10	+	26472758	Jiyoye	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	151812
110593188	110593211	10	-	26472758	Jiyoye	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-5.019089373196225	[42]	[0]	-9	hSpCas9	negative selection	151813
110599707	110599730	10	+	26472758	Jiyoye	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.985142041272887	[83]	[15]	-8	hSpCas9	negative selection	151814
110583463	110583486	10	+	26472758	KBM7	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-1.4073437029430884	[1135,816]	[273,78]	-7	hSpCas9	negative selection	342923
110578641	110578664	10	+	26472758	KBM7	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.4032001890630208	[208,236]	[38,116]	-4	hSpCas9	negative selection	342924
110582621	110582644	10	+	26472758	KBM7	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-3.0056461572594655	[697,389]	[38,23]	-9	hSpCas9	negative selection	342925
110601028	110601051	10	+	26472758	KBM7	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-1.381479972105807	[53,22]	[2,9]	-7	hSpCas9	negative selection	342926
110601759	110601782	10	+	26472758	KBM7	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.3614355586734652	[463,495]	[143,38]	-7	hSpCas9	negative selection	342927
110582023	110582046	10	+	26472758	KBM7	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-1.9188317273752142	[350,189]	[36,28]	-8	hSpCas9	negative selection	342928
110583488	110583511	10	+	26472758	KBM7	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-3.512645845723605	[87,116]	[7,0]	-9	hSpCas9	negative selection	342929
110583931	110583954	10	+	26472758	KBM7	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-0.7841405324260426	[143,66]	[1,50]	-6	hSpCas9	negative selection	342930
110593188	110593211	10	-	26472758	KBM7	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-1.7212391806229717	[171,209]	[5,46]	-8	hSpCas9	negative selection	342931
110599707	110599730	10	+	26472758	KBM7	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.53424920568683	[148,156]	[33,16]	-8	hSpCas9	negative selection	342932
110583463	110583486	10	+	26472758	Raji	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-3.907566806092372	[387]	[5]	-9	hSpCas9	negative selection	534041
110578641	110578664	10	+	26472758	Raji	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.029381023372326176	[75]	[17]	0	hSpCas9	negative selection	534042
110582621	110582644	10	+	26472758	Raji	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-2.0474345736785047	[284]	[15]	-8	hSpCas9	negative selection	534043
110601028	110601051	10	+	26472758	Raji	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-0.6999713866840054	[6]	[0]	-5	hSpCas9	negative selection	534044
110601759	110601782	10	+	26472758	Raji	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.2651706325837309	[144]	[13]	-7	hSpCas9	negative selection	534045
110582023	110582046	10	+	26472758	Raji	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-1.4574010834099265	[70]	[5]	-7	hSpCas9	negative selection	534046
110583488	110583511	10	+	26472758	Raji	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-1.5248846801259135	[61]	[4]	-8	hSpCas9	negative selection	534047
110583931	110583954	10	+	26472758	Raji	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-1.447205316304038	[46]	[3]	-7	hSpCas9	negative selection	534048
110593188	110593211	10	-	26472758	Raji	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-2.235008662073479	[141]	[6]	-9	hSpCas9	negative selection	534049
110599707	110599730	10	+	26472758	Raji	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-2.2000449898186476	[98]	[4]	-8	hSpCas9	negative selection	534050
110583463	110583486	10	+	26472758	K562	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-7.508798021512508	[862]	[3]	-9	hSpCas9	negative selection	725159
110578641	110578664	10	+	26472758	K562	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.9024226606628243	[123]	[55]	-5	hSpCas9	negative selection	725160
110582621	110582644	10	+	26472758	K562	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-4.777949085362008	[454]	[13]	-9	hSpCas9	negative selection	725161
110601028	110601051	10	+	26472758	K562	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-1.3405437730547085	[2]	[0]	-6	hSpCas9	negative selection	725162
110601759	110601782	10	+	26472758	K562	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.6523605519747826	[390]	[104]	-7	hSpCas9	negative selection	725163
110582023	110582046	10	+	26472758	K562	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-2.115477217419936	[153]	[29]	-7	hSpCas9	negative selection	725164
110583488	110583511	10	+	26472758	K562	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-6.85361335529408	[136]	[0]	-9	hSpCas9	negative selection	725165
110583931	110583954	10	+	26472758	K562	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-6.3405437730547085	[95]	[0]	-9	hSpCas9	negative selection	725166
110593188	110593211	10	-	26472758	K562	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-7.399437462108277	[199]	[0]	-9	hSpCas9	negative selection	725167
110599707	110599730	10	+	26472758	K562	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-6.85361335529408	[136]	[0]	-9	hSpCas9	negative selection	725168
110584180	110584203	10	+	26627737	DLD1	viability	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.590153901904098	[249]	[21,17,0]	-9	hSpCas9	negative selection	773663
110589631	110589654	10	+	26627737	DLD1	viability	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.3628013248701396	[434]	[75,42,40]	-8	hSpCas9	negative selection	773664
110590532	110590555	10	-	26627737	DLD1	viability	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.5256643662113558	[530]	[126,100,116]	-5	hSpCas9	negative selection	773665
110593165	110593188	10	+	26627737	DLD1	viability	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-1.1609947420193572	[431]	[43,106,35]	-7	hSpCas9	negative selection	773666
110598178	110598201	10	+	26627737	DLD1	viability	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.437472241124696	[663]	[23,8,74]	-9	hSpCas9	negative selection	773667
110599791	110599814	10	+	26627737	DLD1	viability	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.718925279410509	[404]	[62,94,73]	-6	hSpCas9	negative selection	773668
110584180	110584203	10	+	26627737	GBM cells	viability after 5 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.8985932612155718	[145]	[10,30]	-9	hSpCas9	negative selection	855978
110589631	110589654	10	+	26627737	GBM cells	viability after 5 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.24765847940254693	[382]	[191,153]	-4	hSpCas9	negative selection	855979
110590532	110590555	10	-	26627737	GBM cells	viability after 5 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	0.4017418400423445	[517]	[401,331]	6	hSpCas9	negative selection	855980
110593165	110593188	10	+	26627737	GBM cells	viability after 5 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.3073787202410433	[109]	[78,66]	5	hSpCas9	negative selection	855981
110598178	110598201	10	+	26627737	GBM cells	viability after 5 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.9375873928314351	[374]	[94,114]	-8	hSpCas9	negative selection	855982
110599791	110599814	10	+	26627737	GBM cells	viability after 5 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.30167304438609266	[176]	[115,117]	5	hSpCas9	negative selection	855983
110584180	110584203	10	+	26627737	GBM cells	viability after 13 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.6072817171604776	[145]	[25,25]	-9	hSpCas9	negative selection	938293
110589631	110589654	10	+	26627737	GBM cells	viability after 13 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.21676401382767652	[382]	[153,198]	-3	hSpCas9	negative selection	938294
110590532	110590555	10	-	26627737	GBM cells	viability after 13 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	0.2982358262939018	[517]	[365,328]	4	hSpCas9	negative selection	938295
110593165	110593188	10	+	26627737	GBM cells	viability after 13 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.13692340895094302	[109]	[61,47]	-2	hSpCas9	negative selection	938296
110598178	110598201	10	+	26627737	GBM cells	viability after 13 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-1.128914638033364	[374]	[97,88]	-8	hSpCas9	negative selection	938297
110599791	110599814	10	+	26627737	GBM cells	viability after 13 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.12197805323336963	[176]	[106,72]	-1	hSpCas9	negative selection	938298
110584180	110584203	10	+	26627737	GBM cells	viability after 21 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-0.684775499626921	[145]	[52,45]	-6	hSpCas9	negative selection	1020608
110589631	110589654	10	+	26627737	GBM cells	viability after 21 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	0.1407542988191638	[382]	[219,237]	1	hSpCas9	negative selection	1020609
110590532	110590555	10	-	26627737	GBM cells	viability after 21 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.28600612215048526	[517]	[246,215]	-3	hSpCas9	negative selection	1020610
110593165	110593188	10	+	26627737	GBM cells	viability after 21 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.024345607441243144	[109]	[65,55]	0	hSpCas9	negative selection	1020611
110598178	110598201	10	+	26627737	GBM cells	viability after 21 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-1.106067567546922	[374]	[102,86]	-7	hSpCas9	negative selection	1020612
110599791	110599814	10	+	26627737	GBM cells	viability after 21 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.17772042601600646	[176]	[125,92]	2	hSpCas9	negative selection	1020613
110584180	110584203	10	+	26627737	RPE1	viability after 9 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.2742555993712146	[710]	[21,76]	-9	hSpCas9	negative selection	1102923
110589631	110589654	10	+	26627737	RPE1	viability after 9 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.9426779627006447	[1939]	[277,364]	-6	hSpCas9	negative selection	1102924
110590532	110590555	10	-	26627737	RPE1	viability after 9 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-2.758229185071242	[1849]	[44,137]	-9	hSpCas9	negative selection	1102925
110593165	110593188	10	+	26627737	RPE1	viability after 9 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.6813865055102521	[98]	[26,78]	4	hSpCas9	negative selection	1102926
110598178	110598201	10	+	26627737	RPE1	viability after 9 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-1.7469278731946558	[844]	[80,75]	-8	hSpCas9	negative selection	1102927
110599791	110599814	10	+	26627737	RPE1	viability after 9 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	2.12204579266074	[237]	[250,418]	9	hSpCas9	negative selection	1102928
110584180	110584203	10	+	26627737	RPE1	viability after 12 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.6720783923139764	[710]	[28,30]	-9	hSpCas9	negative selection	1185238
110589631	110589654	10	+	26627737	RPE1	viability after 12 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.4845775824438796	[1939]	[126,248]	-7	hSpCas9	negative selection	1185239
110590532	110590555	10	-	26627737	RPE1	viability after 12 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-3.078753046043248	[1849]	[18,100]	-9	hSpCas9	negative selection	1185240
110593165	110593188	10	+	26627737	RPE1	viability after 12 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-1.5226782224668134	[98]	[0,17]	-8	hSpCas9	negative selection	1185241
110598178	110598201	10	+	26627737	RPE1	viability after 12 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.8376869034143852	[844]	[144,107]	-5	hSpCas9	negative selection	1185242
110599791	110599814	10	+	26627737	RPE1	viability after 12 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	1.6362602367873875	[237]	[275,116]	8	hSpCas9	negative selection	1185243
110584180	110584203	10	+	26627737	RPE1	viability after 15 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.931012388032462	[710]	[38,65]	-8	hSpCas9	negative selection	1267553
110589631	110589654	10	+	26627737	RPE1	viability after 15 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.586337676670484	[1939]	[55,304]	-7	hSpCas9	negative selection	1267554
110590532	110590555	10	-	26627737	RPE1	viability after 15 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-4.099646637905085	[1849]	[0,58]	-9	hSpCas9	negative selection	1267555
110593165	110593188	10	+	26627737	RPE1	viability after 15 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-1.107168028066623	[98]	[12,12]	-6	hSpCas9	negative selection	1267556
110598178	110598201	10	+	26627737	RPE1	viability after 15 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.9199757320526557	[844]	[191,62]	-5	hSpCas9	negative selection	1267557
110599791	110599814	10	+	26627737	RPE1	viability after 15 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	2.1313694751737593	[237]	[408,184]	9	hSpCas9	negative selection	1267558
110584180	110584203	10	+	26627737	RPE1	viability after 18 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.756314769767107	[710]	[39,15]	-9	hSpCas9	negative selection	1349868
110589631	110589654	10	+	26627737	RPE1	viability after 18 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.741520470364215	[1939]	[143,169]	-8	hSpCas9	negative selection	1349869
110590532	110590555	10	-	26627737	RPE1	viability after 18 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-4.0622310293267825	[1849]	[11,48]	-9	hSpCas9	negative selection	1349870
110593165	110593188	10	+	26627737	RPE1	viability after 18 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-1.0298123760979832	[98]	[0,25]	-6	hSpCas9	negative selection	1349871
110598178	110598201	10	+	26627737	RPE1	viability after 18 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.7709844039626232	[844]	[122,144]	-5	hSpCas9	negative selection	1349872
110599791	110599814	10	+	26627737	RPE1	viability after 18 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	2.1118965084168213	[237]	[266,288]	8	hSpCas9	negative selection	1349873
110584180	110584203	10	+	26627737	HeLa	viability after 8 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.21709265787778	[118]	[5,10,14]	-9	hSpCas9	negative selection	1432183
110589631	110589654	10	+	26627737	HeLa	viability after 8 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	0.16232188242514395	[366]	[249,184,120]	1	hSpCas9	negative selection	1432184
110590532	110590555	10	-	26627737	HeLa	viability after 8 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	0.2796100873279864	[690]	[560,195,379]	2	hSpCas9	negative selection	1432185
110593165	110593188	10	+	26627737	HeLa	viability after 8 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.01741702089139041	[276]	[283,85,29]	0	hSpCas9	negative selection	1432186
110598178	110598201	10	+	26627737	HeLa	viability after 8 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	0.027436094567229563	[345]	[65,160,209]	0	hSpCas9	negative selection	1432187
110599791	110599814	10	+	26627737	HeLa	viability after 8 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.17776006504920752	[342]	[266,105,155]	1	hSpCas9	negative selection	1432188
110584180	110584203	10	+	26627737	HeLa	viability after 12 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.0350024009470409	[118]	[0,45,21]	-7	hSpCas9	negative selection	1514498
110589631	110589654	10	+	26627737	HeLa	viability after 12 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.336526801097461	[366]	[120,132,104]	-3	hSpCas9	negative selection	1514499
110590532	110590555	10	-	26627737	HeLa	viability after 12 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.27970002958504936	[690]	[393,143,181]	-2	hSpCas9	negative selection	1514500
110593165	110593188	10	+	26627737	HeLa	viability after 12 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.13701413055922096	[276]	[134,39,144]	-1	hSpCas9	negative selection	1514501
110598178	110598201	10	+	26627737	HeLa	viability after 12 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.7787547978729583	[345]	[69,79,99]	-6	hSpCas9	negative selection	1514502
110599791	110599814	10	+	26627737	HeLa	viability after 12 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.13784037179347558	[342]	[170,158,137]	1	hSpCas9	negative selection	1514503
110584180	110584203	10	+	26627737	HeLa	viability after 15 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.0576179471443905	[118]	[0,22,10]	-9	hSpCas9	negative selection	1596813
110589631	110589654	10	+	26627737	HeLa	viability after 15 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.7896291317443078	[366]	[106,77,72]	-6	hSpCas9	negative selection	1596814
110590532	110590555	10	-	26627737	HeLa	viability after 15 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.6833637515637362	[690]	[225,109,189]	-5	hSpCas9	negative selection	1596815
110593165	110593188	10	+	26627737	HeLa	viability after 15 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.24403640112480118	[276]	[131,35,118]	-2	hSpCas9	negative selection	1596816
110598178	110598201	10	+	26627737	HeLa	viability after 15 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.8723089978772778	[345]	[21,102,108]	-6	hSpCas9	negative selection	1596817
110599791	110599814	10	+	26627737	HeLa	viability after 15 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.05323832557910094	[342]	[102,237,89]	0	hSpCas9	negative selection	1596818
110584180	110584203	10	+	26627737	HeLa	viability after 18 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.039040723593627	[118]	[0,18,10]	-9	hSpCas9	negative selection	1679128
110589631	110589654	10	+	26627737	HeLa	viability after 18 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.8605282522497457	[366]	[64,62,72]	-6	hSpCas9	negative selection	1679129
110590532	110590555	10	-	26627737	HeLa	viability after 18 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.7042822538576319	[690]	[149,86,189]	-6	hSpCas9	negative selection	1679130
110593165	110593188	10	+	26627737	HeLa	viability after 18 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.20117520433691127	[276]	[93,29,118]	-2	hSpCas9	negative selection	1679131
110598178	110598201	10	+	26627737	HeLa	viability after 18 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.8322946427948534	[345]	[15,88,108]	-6	hSpCas9	negative selection	1679132
110599791	110599814	10	+	26627737	HeLa	viability after 18 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.06970068262232276	[342]	[69,199,89]	0	hSpCas9	negative selection	1679133
110584180	110584203	10	+	26627737	HCT116	viability after 6 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.269586184824451	[322]	[12,0]	-9	hSpCas9	negative selection	1761443
110589631	110589654	10	+	26627737	HCT116	viability after 6 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.5255791237731489	[812]	[33,118]	-3	hSpCas9	negative selection	1761444
110590532	110590555	10	-	26627737	HCT116	viability after 6 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.49298134998095655	[796]	[50,109]	-3	hSpCas9	negative selection	1761445
110593165	110593188	10	+	26627737	HCT116	viability after 6 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	2.6142393036859946	[133]	[351,5]	9	hSpCas9	negative selection	1761446
110598178	110598201	10	+	26627737	HCT116	viability after 6 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	0.7582017406916493	[689]	[303,116]	4	hSpCas9	negative selection	1761447
110599791	110599814	10	+	26627737	HCT116	viability after 6 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	1.6588151407605367	[225]	[68,135]	8	hSpCas9	negative selection	1761448
110584180	110584203	10	+	26627737	HCT116	viability after 8 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-0.8929917470576589	[139]	[55,36,31]	-8	hSpCas9	negative selection	1843758
110589631	110589654	10	+	26627737	HCT116	viability after 8 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.7626851751739737	[392]	[98,122,159]	-7	hSpCas9	negative selection	1843759
110590532	110590555	10	-	26627737	HCT116	viability after 8 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.2723942152129505	[536]	[333,193,208]	-3	hSpCas9	negative selection	1843760
110593165	110593188	10	+	26627737	HCT116	viability after 8 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	1.169281817130957	[88]	[80,191,57]	8	hSpCas9	negative selection	1843761
110598178	110598201	10	+	26627737	HCT116	viability after 8 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.6615982826923417	[484]	[15,47,61]	-9	hSpCas9	negative selection	1843762
110599791	110599814	10	+	26627737	HCT116	viability after 8 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.2139891532824009	[285]	[137,162,106]	-2	hSpCas9	negative selection	1843763
110584180	110584203	10	+	26627737	HCT116	viability after 9 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-4.9627215643203835	[322]	[4,0]	-9	hSpCas9	negative selection	1926073
110589631	110589654	10	+	26627737	HCT116	viability after 9 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.5864317064594844	[812]	[121,32]	-8	hSpCas9	negative selection	1926074
110590532	110590555	10	-	26627737	HCT116	viability after 9 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.11000945410121138	[796]	[409,28]	0	hSpCas9	negative selection	1926075
110593165	110593188	10	+	26627737	HCT116	viability after 9 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.22159279624928319	[133]	[10,65]	1	hSpCas9	negative selection	1926076
110598178	110598201	10	+	26627737	HCT116	viability after 9 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.4569507248451244	[689]	[50,199]	-3	hSpCas9	negative selection	1926077
110599791	110599814	10	+	26627737	HCT116	viability after 9 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.24940512235224177	[225]	[52,48]	-2	hSpCas9	negative selection	1926078
110584180	110584203	10	+	26627737	HCT116	viability after 12 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.4314569140861533	[139]	[14,21,3]	-9	hSpCas9	negative selection	2008388
110589631	110589654	10	+	26627737	HCT116	viability after 12 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.606894524434252	[392]	[56,93,53]	-9	hSpCas9	negative selection	2008389
110590532	110590555	10	-	26627737	HCT116	viability after 12 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.8151492405025779	[536]	[164,210,105]	-7	hSpCas9	negative selection	2008390
110593165	110593188	10	+	26627737	HCT116	viability after 12 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.10669858524233722	[88]	[18,106,7]	-1	hSpCas9	negative selection	2008391
110598178	110598201	10	+	26627737	HCT116	viability after 12 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.7043341889088066	[484]	[52,34,27]	-9	hSpCas9	negative selection	2008392
110599791	110599814	10	+	26627737	HCT116	viability after 12 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.4055503688623706	[285]	[92,104,143]	-4	hSpCas9	negative selection	2008393
110584180	110584203	10	+	26627737	HCT116	viability after 15 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.4639482157908708	[139]	[0,4,14]	-9	hSpCas9	negative selection	2090703
110589631	110589654	10	+	26627737	HCT116	viability after 15 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.3703802789139725	[392]	[63,102,91]	-8	hSpCas9	negative selection	2090704
110590532	110590555	10	-	26627737	HCT116	viability after 15 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.819353070200546	[536]	[257,148,127]	-7	hSpCas9	negative selection	2090705
110593165	110593188	10	+	26627737	HCT116	viability after 15 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	1.4235781944940982	[88]	[76,188,137]	9	hSpCas9	negative selection	2090706
110598178	110598201	10	+	26627737	HCT116	viability after 15 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.4589410272867576	[484]	[112,31,14]	-9	hSpCas9	negative selection	2090707
110599791	110599814	10	+	26627737	HCT116	viability after 15 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.08603604748118826	[285]	[167,156,140]	-1	hSpCas9	negative selection	2090708
110584180	110584203	10	+	26627737	HCT116	viability after 18 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.372442392400134	[139]	[0,13,3]	-9	hSpCas9	negative selection	2173018
110589631	110589654	10	+	26627737	HCT116	viability after 18 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.7853688879416878	[392]	[74,49,39]	-8	hSpCas9	negative selection	2173019
110590532	110590555	10	-	26627737	HCT116	viability after 18 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-1.2524253124495537	[536]	[107,159,52]	-8	hSpCas9	negative selection	2173020
110593165	110593188	10	+	26627737	HCT116	viability after 18 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.9114531951909781	[88]	[35,148,51]	7	hSpCas9	negative selection	2173021
110598178	110598201	10	+	26627737	HCT116	viability after 18 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.5393676709543693	[484]	[21,64,31]	-9	hSpCas9	negative selection	2173022
110599791	110599814	10	+	26627737	HCT116	viability after 18 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.08266769315877631	[285]	[136,143,158]	0	hSpCas9	negative selection	2173023
110567810	110567833	10	+	24336569	HL60	viability	CGGAATCATGTACATAAAGCAGG	SMC3	ENSG00000108055	0.7160430354723605	[293]	[1021]	6	hSpCas9	negative selection	2295873
110568928	110568951	10	+	24336569	HL60	viability	TATTTACTAGGTGATTATCCAGG	SMC3	ENSG00000108055	-0.04954892055213411	[379]	[776]	0	hSpCas9	negative selection	2295874
110573703	110573726	10	+	24336569	HL60	viability	CCAGTGGGCAGAAATGGATCTGG	SMC3	ENSG00000108055	-0.366367686423281	[677]	[1112]	-3	hSpCas9	negative selection	2295875
110575332	110575355	10	-	24336569	HL60	viability	CTGAGAACAAACTGAATTGCTGG	SMC3	ENSG00000108055	-0.011944652197611094	[789]	[1657]	0	hSpCas9	negative selection	2295876
110575366	110575389	10	+	24336569	HL60	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.4225010184639633	[512]	[404]	-8	hSpCas9	negative selection	2295877
110575377	110575400	10	-	24336569	HL60	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-1.1596588310090945	[416]	[394]	-8	hSpCas9	negative selection	2295878
110577850	110577873	10	+	24336569	HL60	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.30534684584332017	[399]	[1045]	3	hSpCas9	negative selection	2295879
110577888	110577911	10	+	24336569	HL60	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	0.486747035802935	[230]	[684]	4	hSpCas9	negative selection	2295880
110578641	110578664	10	+	24336569	HL60	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.46801304294804436	[584]	[894]	-4	hSpCas9	negative selection	2295881
110578680	110578703	10	+	24336569	HL60	viability	CCTTATTATATTGTTAAACAAGG	SMC3	ENSG00000108055	0.49378324525904804	[148]	[443]	4	hSpCas9	negative selection	2295882
110567810	110567833	10	+	24336569	KBM7	viability	CGGAATCATGTACATAAAGCAGG	SMC3	ENSG00000108055	-0.7042958786261979	[318]	[533]	-5	hSpCas9	negative selection	2363050
110568928	110568951	10	+	24336569	KBM7	viability	TATTTACTAGGTGATTATCCAGG	SMC3	ENSG00000108055	-0.6795505946973477	[339]	[578]	-5	hSpCas9	negative selection	2363051
110573703	110573726	10	+	24336569	KBM7	viability	CCAGTGGGCAGAAATGGATCTGG	SMC3	ENSG00000108055	0.1714859566578423	[431]	[1326]	1	hSpCas9	negative selection	2363052
110575332	110575355	10	-	24336569	KBM7	viability	CTGAGAACAAACTGAATTGCTGG	SMC3	ENSG00000108055	0.9043021204401077	[428]	[2189]	7	hSpCas9	negative selection	2363053
110575366	110575389	10	+	24336569	KBM7	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.728315604116135	[327]	[134]	-9	hSpCas9	negative selection	2363054
110575377	110575400	10	-	24336569	KBM7	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	1.6579552176234746	[111]	[963]	9	hSpCas9	negative selection	2363055
110577850	110577873	10	+	24336569	KBM7	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	1.185388677083106	[265]	[1649]	8	hSpCas9	negative selection	2363056
110577888	110577911	10	+	24336569	KBM7	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-3.3450094629083345	[189]	[50]	-9	hSpCas9	negative selection	2363057
110578641	110578664	10	+	24336569	KBM7	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-1.0240602205149476	[635]	[852]	-6	hSpCas9	negative selection	2363058
110578680	110578703	10	+	24336569	KBM7	viability	CCTTATTATATTGTTAAACAAGG	SMC3	ENSG00000108055	1.329096107419295	[128]	[883]	9	hSpCas9	negative selection	2363059
110587445	110587468	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGTGGACGGATCACGAGG	SMC3	ENSG00000108055	0.16474050611641577	[16,25]	[4,4]	0	dCas9-VP64	positive selection	2448773
110586888	110586911	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCCACCTGAG	SMC3	ENSG00000108055	-1.8266088487663314	[149,166]	[13,3]	-8	dCas9-VP64	positive selection	2465139
110599248	110599271	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGAGG	SMC3	ENSG00000108055	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473443
110587445	110587468	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGTGGACGGATCACGAGG	SMC3	ENSG00000108055	0.6847734529827498	[13,14]	[8,5]	5	dCas9-VP64	positive selection	2544028
110586888	110586911	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCCACCTGAG	SMC3	ENSG00000108055	0.6108739619638027	[154,293]	[174,51]	4	dCas9-VP64	positive selection	2560394
110599248	110599271	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGAGG	SMC3	ENSG00000108055	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568698
110577433	110577456	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	-0.2036547356718405	[2,2]	[3,0]	-3	hSpCas9	positive selection	3022088
110583464	110583487	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-0.3173701031425891	[2,2]	[1,1]	-4	hSpCas9	positive selection	3022089
110575367	110575390	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.1795549758814986	[1,2]	[1,0]	-3	hSpCas9	positive selection	3022090
110584244	110584267	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	-0.6651285228522646	[2,3]	[1,1]	-7	hSpCas9	positive selection	3022091
110577433	110577456	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	-0.4343655245958919	[2,2]	[2,0]	-6	hSpCas9	positive selection	3089946
110583464	110583487	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	0.6553285534053639	[2,2]	[4,1]	9	hSpCas9	positive selection	3089947
110575367	110575390	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.3714443504894519	[1,1]	[1,0]	-5	hSpCas9	positive selection	3089948
110584244	110584267	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	0.026590089716585885	[2,2]	[1,1]	0	hSpCas9	positive selection	3089949
110575377	110575400		-	24336571	A375	resistance to PLX after 7 days	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.13215458388010487	[10,10]	[10,12]	4	hSpCas9	positive selection	3146147
110568987	110569010		-	24336571	A375	resistance to PLX after 7 days	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	-0.3173314131793187	[25,15]	[15,17]	-8	hSpCas9	positive selection	3146148
110568946	110568969		-	24336571	A375	resistance to PLX after 7 days	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.28221316908084837	[6,4]	[6,6]	7	hSpCas9	positive selection	3146149
110575377	110575400		-	24336571	A375	resistance to PLX after 14 days	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.19127347462929123	[10,10]	[5,4]	2	hSpCas9	positive selection	3203940
110568987	110569010		-	24336571	A375	resistance to PLX after 14 days	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	1.6400261230574853	[26,15]	[31,30]	9	hSpCas9	positive selection	3203941
110568946	110568969		-	24336571	A375	resistance to PLX after 14 days	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.2549426950566812	[7,4]	[2,3]	2	hSpCas9	positive selection	3203942
110575377	110575400		-	24336571	A375	viability after 7 days	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.03372936752524286	[10]	[10,10]	0	hSpCas9	negative selection	3261733
110568987	110569010		-	24336571	A375	viability after 7 days	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	0.28750585558117936	[17]	[25,15]	4	hSpCas9	negative selection	3261734
110568946	110568969		-	24336571	A375	viability after 7 days	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-1.7491829631203313	[21]	[6,4]	-9	hSpCas9	negative selection	3261735
110575377	110575400		-	24336571	A375	viability after 14 days	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.09208556761067643	[10]	[10,10]	1	hSpCas9	negative selection	3319526
110568987	110569010		-	24336571	A375	viability after 14 days	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	0.32556172545520323	[17]	[26,15]	4	hSpCas9	negative selection	3319527
110568946	110568969		-	24336571	A375	viability after 14 days	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-1.6058584945551708	[21]	[7,4]	-9	hSpCas9	negative selection	3319528
110577850	110577873	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	-1.2818325996621964	[371,371]	[0,0]	-8	hSpCas9	positive selection	3393813
110568992	110569015	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	0.4244361972810935	[113,113]	[0,0]	2	hSpCas9	positive selection	3393814
110577888	110577911	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3393815
110577433	110577456	10	-	26780180	HT29	viability (Avana library 4 designs)	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	3.93795743463499	[]	[]	9	hSpCas9	negative selection	3460664
110583463	110583486	10	+	26780180	HT29	viability (Avana library 4 designs)	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	5.71429624421	[]	[]	9	hSpCas9	negative selection	3460665
110575366	110575389	10	+	26780180	HT29	viability (Avana library 4 designs)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	5.08797116539597	[]	[]	9	hSpCas9	negative selection	3460666
110584243	110584266	10	+	26780180	HT29	viability (Avana library 4 designs)	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	4.56716288916205	[]	[]	9	hSpCas9	negative selection	3460667
110575366	110575389	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-9.77081058929426	[]	[]	-7	hSpCas9	negative selection	3561150
110577433	110577456	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	-8.45275749437233	[]	[]	-7	hSpCas9	negative selection	3561151
110583463	110583486	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-13.0382321493334	[]	[]	-8	hSpCas9	negative selection	3561152
110584243	110584266	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	-21.2883554102331	[]	[]	-9	hSpCas9	negative selection	3561153
110583931	110583954	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-4.17881672153807	[]	[]	-5	hSpCas9	negative selection	3561154
110582621	110582644	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-9.19835598159067	[]	[]	-7	hSpCas9	negative selection	3561155
110575366	110575389	10	+	26780180	A375	viability (Avana lentiGuide)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	12.295033799284	[]	[]	7	hSpCas9	negative selection	3669809
110577433	110577456	10	-	26780180	A375	viability (Avana lentiGuide)	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	8.54822777756396	[]	[]	6	hSpCas9	negative selection	3669810
110583463	110583486	10	+	26780180	A375	viability (Avana lentiGuide)	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	18.9133404121035	[]	[]	8	hSpCas9	negative selection	3669811
110584243	110584266	10	+	26780180	A375	viability (Avana lentiGuide)	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	2.25265834922072	[]	[]	2	hSpCas9	negative selection	3669812
110583931	110583954	10	+	26780180	A375	viability (Avana lentiGuide)	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	5.28644392570242	[]	[]	5	hSpCas9	negative selection	3669813
110582621	110582644	10	+	26780180	A375	viability (Avana lentiGuide)	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	16.9115789251149	[]	[]	8	hSpCas9	negative selection	3669814
110575366	110575389	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.6330001116930654	[5]	[2,3]	-7	hSpCas9	positive selection	3778416
110577433	110577456	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	-0.830881682726373	[5]	[3,1]	-8	hSpCas9	positive selection	3778417
110583463	110583486	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-1.2949716260633803	[5]	[1,1]	-9	hSpCas9	positive selection	3778418
110584243	110584266	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	-1.1250561740155751	[8]	[4,2]	-9	hSpCas9	positive selection	3778419
110583931	110583954	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-0.6675431831246812	[5]	[2,2]	-7	hSpCas9	positive selection	3778420
110582621	110582644	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-1.0144056727276272	[5]	[0,2]	-8	hSpCas9	positive selection	3778421
110575366	110575389	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.3856664279971525	[5]	[0,2]	-9	hSpCas9	positive selection	3887023
110577433	110577456	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAAAGCAGAAATAACACGAGG	SMC3	ENSG00000108055	-1.4175123730828374	[4]	[0,0]	-9	hSpCas9	positive selection	3887024
110583463	110583486	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-1.6433119503717268	[5]	[1,0]	-9	hSpCas9	positive selection	3887025
110584243	110584266	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTACATCAAAAGAAGAAAGGG	SMC3	ENSG00000108055	-0.8122341000141425	[5]	[2,1]	-7	hSpCas9	positive selection	3887026
110583931	110583954	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-1.0277074638004122	[4]	[1,1]	-8	hSpCas9	positive selection	3887027
110582621	110582644	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-2.37728325561506	[5]	[0,0]	-9	hSpCas9	positive selection	3887028
110575377	110575400	10	-	26780180	A375	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.520493199562397	[]	[]	1	hSpCas9	negative selection	3997137
110568992	110569015	10	+	26780180	A375	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	1.75877159736377	[]	[]	9	hSpCas9	negative selection	3997138
110568946	110568969	10	-	26780180	A375	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	1.92108595121352	[]	[]	9	hSpCas9	negative selection	3997139
110577888	110577911	10	+	26780180	A375	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	0.814142782090319	[]	[]	3	hSpCas9	negative selection	3997140
110575366	110575389	10	+	26780180	A375	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	1.43835039797448	[]	[]	8	hSpCas9	negative selection	3997141
110577850	110577873	10	+	26780180	A375	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.404924338696136	[]	[]	1	hSpCas9	negative selection	3997142
110575377	110575400	10	-	26780180	HT29	viability (GeCKOv2 library)	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.715935277286112	[]	[]	2	hSpCas9	negative selection	4105103
110568992	110569015	10	+	26780180	HT29	viability (GeCKOv2 library)	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	2.43199050931071	[]	[]	9	hSpCas9	negative selection	4105104
110568946	110568969	10	-	26780180	HT29	viability (GeCKOv2 library)	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	2.51540145961665	[]	[]	9	hSpCas9	negative selection	4105105
110577888	110577911	10	+	26780180	HT29	viability (GeCKOv2 library)	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	1.18688657307381	[]	[]	6	hSpCas9	negative selection	4105106
110575366	110575389	10	+	26780180	HT29	viability (GeCKOv2 library)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	2.01407662589657	[]	[]	9	hSpCas9	negative selection	4105107
110577850	110577873	10	+	26780180	HT29	viability (GeCKOv2 library)	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.54783310120982	[]	[]	1	hSpCas9	negative selection	4105108
110575377	110575400	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.03513182372899884	[3]	[2,2]	-1	hSpCas9	positive selection	4172226
110568987	110569010	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	0.28979194097614813	[4]	[1,4]	7	hSpCas9	positive selection	4172227
110568946	110568969	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.1264330325861055	[2]	[1,1]	-3	hSpCas9	positive selection	4172228
110575377	110575400	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.7504138753978775	[3]	[1,1,1,3]	5	hSpCas9	positive selection	4236248
110568987	110569010	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACATTATGTTTTGAACTGAAGG	SMC3	ENSG00000108055	1.1757224742924237	[4]	[3,0,5,4]	8	hSpCas9	positive selection	4236249
110568946	110568969	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.08459987104348787	[3]	[3,0,2,0]	-1	hSpCas9	positive selection	4236250
110575377	110575400	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.3742005432905817	[3]	[3,3]	7	hSpCas9	positive selection	4299279
110568946	110568969	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.6792634459237542	[2]	[1,0]	-9	hSpCas9	positive selection	4299280
110575366	110575389	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.6498102965908753	[2]	[1,0]	-9	hSpCas9	positive selection	4299281
110577850	110577873	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.07847968477497258	[3]	[3,2]	1	hSpCas9	positive selection	4363532
110568992	110569015	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.3215873502509948	[2]	[1,1]	-6	hSpCas9	positive selection	4363533
110577888	110577911	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.6936130244936319	[1]	[0,0]	-9	hSpCas9	positive selection	4363534
110584181	110584203	10	+	27760321	OCIAML3	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-0.9276227484692591	[634,601]	[264,240]	-7	hSpCas9	negative selection	4441322
110584208	110584230	10	+	27760321	OCIAML3	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-0.493533092507602	[464,308]	[100,356]	-5	hSpCas9	negative selection	4441323
110590449	110590471	10	+	27760321	OCIAML3	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.9808715405553511	[335,258]	[103,133]	-7	hSpCas9	negative selection	4441324
110580970	110580992	10	+	27760321	OCIAML3	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-0.9982666919719541	[59,51]	[20,22]	-7	hSpCas9	negative selection	4441325
110582566	110582588	10	+	27760321	OCIAML3	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-1.7766614226676702	[142,120]	[16,46]	-9	hSpCas9	negative selection	4441326
110584181	110584203	10	+	27760321	OCIAML2	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.7793074946257446	[634,601]	[94,212]	-9	hSpCas9	negative selection	4524785
110584208	110584230	10	+	27760321	OCIAML2	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-1.0830157061327774	[464,308]	[150,138]	-7	hSpCas9	negative selection	4524786
110590449	110590471	10	+	27760321	OCIAML2	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.3776135387863129	[335,258]	[179,188]	-4	hSpCas9	negative selection	4524787
110580970	110580992	10	+	27760321	OCIAML2	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	0.11962077705377716	[59,51]	[14,93]	1	hSpCas9	negative selection	4524788
110582566	110582588	10	+	27760321	OCIAML2	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-1.4995608802732254	[142,120]	[28,48]	-8	hSpCas9	negative selection	4524789
110584181	110584203	10	+	27760321	MV411	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.0832623917562112	[634,601]	[0,480]	-6	hSpCas9	negative selection	4608248
110584208	110584230	10	+	27760321	MV411	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-0.2515566748908181	[464,308]	[299,78]	-2	hSpCas9	negative selection	4608249
110590449	110590471	10	+	27760321	MV411	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-1.346693149634055	[335,258]	[106,30]	-7	hSpCas9	negative selection	4608250
110580970	110580992	10	+	27760321	MV411	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-0.8127726797314447	[59,51]	[0,50]	-5	hSpCas9	negative selection	4608251
110582566	110582588	10	+	27760321	MV411	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-3.3695278766841392	[142,120]	[5,11]	-9	hSpCas9	negative selection	4608252
110584181	110584203	10	+	27760321	HL60	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.1975588834001751	[634,601]	[204,236]	-8	hSpCas9	negative selection	4691711
110584208	110584230	10	+	27760321	HL60	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-1.0199830150932698	[464,308]	[147,159]	-7	hSpCas9	negative selection	4691712
110590449	110590471	10	+	27760321	HL60	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.4696680825678844	[335,258]	[180,166]	-5	hSpCas9	negative selection	4691713
110580970	110580992	10	+	27760321	HL60	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	0.8659799173184246	[59,51]	[104,59]	8	hSpCas9	negative selection	4691714
110582566	110582588	10	+	27760321	HL60	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-1.2460996712726395	[142,120]	[21,69]	-8	hSpCas9	negative selection	4691715
110584181	110584203	10	+	27760321	HT1080	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-4.988077198622982	[601,469]	[0,12]	-8	hSpCas9	negative selection	4775174
110584208	110584230	10	+	27760321	HT1080	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-6.775410294281782	[308,240]	[0,0]	-9	hSpCas9	negative selection	4775175
110590449	110590471	10	+	27760321	HT1080	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-5.553793961825635	[258,201]	[0,2]	-8	hSpCas9	negative selection	4775176
110580970	110580992	10	+	27760321	HT1080	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	1.8385252758754074	[51,40]	[82,47]	8	hSpCas9	negative selection	4775177
110582566	110582588	10	+	27760321	HT1080	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-5.4276021761212325	[120,94]	[0,0]	-8	hSpCas9	negative selection	4775178
110584181	110584203	10	+	27760321	HT29	viability after 7 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-0.7820852864430845	[601,469]	[581,290,355]	-8	hSpCas9	negative selection	4858637
110584208	110584230	10	+	27760321	HT29	viability after 7 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-0.19791682832460578	[308,240]	[522,222,211]	-3	hSpCas9	negative selection	4858638
110590449	110590471	10	+	27760321	HT29	viability after 7 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.2654561610096121	[258,201]	[410,177,175]	-4	hSpCas9	negative selection	4858639
110580970	110580992	10	+	27760321	HT29	viability after 7 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-0.21876716589471945	[51,40]	[130,30,4]	-3	hSpCas9	negative selection	4858640
110582566	110582588	10	+	27760321	HT29	viability after 7 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-0.7118119835120436	[120,94]	[4,59,174]	-7	hSpCas9	negative selection	4858641
110584181	110584203	10	+	27760321	HT29	viability after 25 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.6394157722197824	[601,469]	[28,58,61]	-9	hSpCas9	negative selection	4942100
110584208	110584230	10	+	27760321	HT29	viability after 25 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-1.7470591954421253	[308,240]	[74,120,84]	-7	hSpCas9	negative selection	4942101
110590449	110590471	10	+	27760321	HT29	viability after 25 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-2.488652944083121	[258,201]	[30,26,87]	-8	hSpCas9	negative selection	4942102
110580970	110580992	10	+	27760321	HT29	viability after 25 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-2.0540361506186318	[51,40]	[32,0,1]	-8	hSpCas9	negative selection	4942103
110582566	110582588	10	+	27760321	HT29	viability after 25 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-4.121226077390163	[120,94]	[0,1,19]	-9	hSpCas9	negative selection	4942104
110584181	110584203	10	+	27760321	HT29	viability after 22 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.6368343561724514	[601,469]	[31,59,57]	-9	hSpCas9	negative selection	5025563
110584208	110584230	10	+	27760321	HT29	viability after 22 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-2.3435886777958763	[308,240]	[77,96,11]	-8	hSpCas9	negative selection	5025564
110590449	110590471	10	+	27760321	HT29	viability after 22 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-2.2782570003930807	[258,201]	[52,39,71]	-8	hSpCas9	negative selection	5025565
110580970	110580992	10	+	27760321	HT29	viability after 22 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-4.31535523979761	[51,40]	[5,0,0]	-9	hSpCas9	negative selection	5025566
110582566	110582588	10	+	27760321	HT29	viability after 22 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-4.238511737477987	[120,94]	[3,0,14]	-9	hSpCas9	negative selection	5025567
110584181	110584203	10	+	27760321	HT29	viability after 19 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-4.279623661781252	[601,469]	[53,10,31]	-9	hSpCas9	negative selection	5109026
110584208	110584230	10	+	27760321	HT29	viability after 19 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-1.9019817171708424	[308,240]	[200,42,22]	-8	hSpCas9	negative selection	5109027
110590449	110590471	10	+	27760321	HT29	viability after 19 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.7251065857397287	[258,201]	[294,24,171]	-5	hSpCas9	negative selection	5109028
110580970	110580992	10	+	27760321	HT29	viability after 19 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-2.636459379437636	[51,40]	[12,0,11]	-8	hSpCas9	negative selection	5109029
110582566	110582588	10	+	27760321	HT29	viability after 19 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-6.511500986582476	[120,94]	[0,0,1]	-9	hSpCas9	negative selection	5109030
110584181	110584203	10	+	27760321	HT29	viability after 16 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.281611463340971	[601,469]	[148,100,122]	-8	hSpCas9	negative selection	5192489
110584208	110584230	10	+	27760321	HT29	viability after 16 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-2.137012447377782	[308,240]	[117,83,11]	-8	hSpCas9	negative selection	5192490
110590449	110590471	10	+	27760321	HT29	viability after 16 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-1.2425777688027926	[258,201]	[181,63,88]	-7	hSpCas9	negative selection	5192491
110580970	110580992	10	+	27760321	HT29	viability after 16 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-3.289344958081649	[51,40]	[14,0,0]	-9	hSpCas9	negative selection	5192492
110582566	110582588	10	+	27760321	HT29	viability after 16 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-3.7433039216906723	[120,94]	[5,0,19]	-9	hSpCas9	negative selection	5192493
110584181	110584203	10	+	27760321	HT29	viability after 13 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.800482177855205	[601,469]	[16,179,71]	-9	hSpCas9	negative selection	5275952
110584208	110584230	10	+	27760321	HT29	viability after 13 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-1.283796275371691	[308,240]	[121,189,83]	-8	hSpCas9	negative selection	5275953
110590449	110590471	10	+	27760321	HT29	viability after 13 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-1.2712494758340942	[258,201]	[83,113,132]	-8	hSpCas9	negative selection	5275954
110580970	110580992	10	+	27760321	HT29	viability after 13 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-0.23671468402801343	[51,40]	[137,0,0]	-3	hSpCas9	negative selection	5275955
110582566	110582588	10	+	27760321	HT29	viability after 13 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-2.671899473065749	[120,94]	[11,9,35]	-9	hSpCas9	negative selection	5275956
110584181	110584203	10	+	27760321	HT29	viability after 10 days	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.1448516945030556	[601,469]	[191,133,127]	-9	hSpCas9	negative selection	5359415
110584208	110584230	10	+	27760321	HT29	viability after 10 days	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	0.3160969778184055	[308,240]	[455,609,225]	4	hSpCas9	negative selection	5359416
110590449	110590471	10	+	27760321	HT29	viability after 10 days	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.7689536151601022	[258,201]	[209,77,214]	-7	hSpCas9	negative selection	5359417
110580970	110580992	10	+	27760321	HT29	viability after 10 days	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-1.9578488445189657	[51,40]	[0,23,19]	-9	hSpCas9	negative selection	5359418
110582566	110582588	10	+	27760321	HT29	viability after 10 days	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-2.9273871708243853	[120,94]	[3,19,28]	-9	hSpCas9	negative selection	5359419
110584181	110584203	10	+	27760321	MOLM13	viability	AGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.848678684575565	[634,601]	[61,36]	-8	hSpCas9	negative selection	5442878
110584208	110584230	10	+	27760321	MOLM13	viability	ACGGATCTTTATGCAAAGCAGG	SMC3	ENSG00000108055	-2.6186052997052385	[464,308]	[33,35]	-8	hSpCas9	negative selection	5442879
110590449	110590471	10	+	27760321	MOLM13	viability	TAGACCACTTCCGTCGAAAAGG	SMC3	ENSG00000108055	-0.23000408369494885	[335,258]	[268,33]	-1	hSpCas9	negative selection	5442880
110580970	110580992	10	+	27760321	MOLM13	viability	AGAGTGTATGACGAACGAAAGG	SMC3	ENSG00000108055	-4.977893540025537	[59,51]	[0,0]	-9	hSpCas9	negative selection	5442881
110582566	110582588	10	+	27760321	MOLM13	viability	CTGCTAAGCGAGAGACTAGTGG	SMC3	ENSG00000108055	-1.8236864019956351	[142,120]	[7,31]	-7	hSpCas9	negative selection	5442882
110567706	110567729	10	+	27661255	K562	viability	GGGAGCGAGCGGCGCTTTGGGGG	SMC3	ENSG00000108055	-0.4755701159102468	[181,263]	[116,135]	-7	dCas9-KRAB	negative selection	5512870
110567762	110567785	10	+	27661255	K562	viability	GCCGTGCGGTTGCTGCTCCGGGG	SMC3	ENSG00000108055	-3.6864765285201426	[616,719]	[49,33]	-9	dCas9-KRAB	negative selection	5512871
110568075	110568098	10	+	27661255	K562	viability	GATCTCCGAGAGGTGTGGAAGGG	SMC3	ENSG00000108055	-1.3379164548374933	[572,744]	[223,192]	-9	dCas9-KRAB	negative selection	5512872
110567755	110567778	10	-	27661255	K562	viability	GCAGCAACCGCACGGCCGCAGGG	SMC3	ENSG00000108055	-0.6507414599232499	[1248,1448]	[771,609]	-8	dCas9-KRAB	negative selection	5512873
110567854	110567877	10	-	27661255	K562	viability	GCCCTTACCGGCCCATGACGGGG	SMC3	ENSG00000108055	-0.9796220767179911	[139,204]	[90,50]	-8	dCas9-KRAB	negative selection	5512874
110567920	110567943	10	-	27661255	K562	viability	GGTCCAGCCTGTGGAGACAGGGG	SMC3	ENSG00000108055	0.10466538581354301	[762,919]	[877,585]	3	dCas9-KRAB	negative selection	5512875
110575377	110575400	10	-	27260156	BXPC3	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.11772518611176189	[576]	[470,478,633,664]	-3	hSpCas9	negative selection	5571739
110568946	110568969	10	-	27260156	BXPC3	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.5975630195336995	[299]	[139,239,236,217]	-8	hSpCas9	negative selection	5571740
110575366	110575389	10	+	27260156	BXPC3	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.8007844237882518	[206]	[78,107,160,158]	-9	hSpCas9	negative selection	5571741
110577850	110577873	10	+	27260156	BXPC3	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.10437060209075488	[792]	[785,766,1042,997]	2	hSpCas9	negative selection	5635992
110568992	110569015	10	+	27260156	BXPC3	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8648560519272239	[444]	[206,268,246,307]	-9	hSpCas9	negative selection	5635993
110577888	110577911	10	+	27260156	BXPC3	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.3398430562432022	[79]	[20,51,25,32]	-9	hSpCas9	negative selection	5635994
110575377	110575400	10	-	27260156	A673	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.35809179985500456	[576]	[687,392,512,590]	-7	hSpCas9	negative selection	5692990
110568946	110568969	10	-	27260156	A673	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.1895908892192013	[299]	[318,293,342,306]	-5	hSpCas9	negative selection	5692991
110575366	110575389	10	+	27260156	A673	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.47064087156344536	[206]	[185,174,162,194]	-8	hSpCas9	negative selection	5692992
110577850	110577873	10	+	27260156	A673	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.10779061192058725	[792]	[1083,981,930,1118]	2	hSpCas9	negative selection	5757243
110568992	110569015	10	+	27260156	A673	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.6573745187231343	[444]	[496,294,224,358]	-9	hSpCas9	negative selection	5757244
110577888	110577911	10	+	27260156	A673	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.8175504697978666	[79]	[70,52,40,54]	-9	hSpCas9	negative selection	5757245
110575377	110575400	10	-	27260156	A375	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.40326213204529926	[576]	[448,472,415,672]	-5	hSpCas9	negative selection	5814241
110568946	110568969	10	-	27260156	A375	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.6573412204361765	[299]	[274,281,241,110]	-7	hSpCas9	negative selection	5814242
110575366	110575389	10	+	27260156	A375	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.927639178192816	[206]	[69,106,55,30]	-9	hSpCas9	negative selection	5814243
110577850	110577873	10	+	27260156	A375	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.5352525862901977	[792]	[1085,1592,1404,1315]	7	hSpCas9	negative selection	5878494
110568992	110569015	10	+	27260156	A375	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.0171748953420363	[444]	[264,286,318,169]	-8	hSpCas9	negative selection	5878495
110577888	110577911	10	+	27260156	A375	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.7335986417530833	[79]	[52,74,96,7]	-7	hSpCas9	negative selection	5878496
110575377	110575400	10	-	27260156	COLO741	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.023392025938166694	[576]	[801,780,606]	0	hSpCas9	negative selection	5935492
110568946	110568969	10	-	27260156	COLO741	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.8581252887062302	[299]	[301,205,138]	-9	hSpCas9	negative selection	5935493
110575366	110575389	10	+	27260156	COLO741	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.8583664026134248	[206]	[37,107,69]	-9	hSpCas9	negative selection	5935494
110577850	110577873	10	+	27260156	COLO741	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.050952093034950074	[792]	[1220,1018,929]	1	hSpCas9	negative selection	5999745
110568992	110569015	10	+	27260156	COLO741	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.802694279859153	[444]	[276,368,326]	-9	hSpCas9	negative selection	5999746
110577888	110577911	10	+	27260156	COLO741	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.4927719314342367	[79]	[2,78,24]	-9	hSpCas9	negative selection	5999747
110575377	110575400	10	-	27260156	CAL120	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.4443884246683507	[576]	[404,613,544]	-6	hSpCas9	negative selection	6056743
110568946	110568969	10	-	27260156	CAL120	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.5540325275745285	[299]	[271,329,164]	-7	hSpCas9	negative selection	6056744
110575366	110575389	10	+	27260156	CAL120	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-3.404883169230069	[206]	[9,47,12]	-9	hSpCas9	negative selection	6056745
110577850	110577873	10	+	27260156	CAL120	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.31359207689663215	[792]	[1476,1103,1136]	5	hSpCas9	negative selection	6120996
110568992	110569015	10	+	27260156	CAL120	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.7952286248891225	[444]	[230,174,533]	-8	hSpCas9	negative selection	6120997
110577888	110577911	10	+	27260156	CAL120	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.2507593388727756	[79]	[41,23,176]	-4	hSpCas9	negative selection	6120998
110575377	110575400	10	-	27260156	CADOES1	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.5020627912769744	[576]	[385,331,432,363]	-7	hSpCas9	negative selection	6177994
110568946	110568969	10	-	27260156	CADOES1	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.5442561347982994	[299]	[205,102,139,320]	-7	hSpCas9	negative selection	6177995
110575366	110575389	10	+	27260156	CADOES1	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.0380348127695649	[206]	[110,96,123,40]	-9	hSpCas9	negative selection	6177996
110577850	110577873	10	+	27260156	CADOES1	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.22730066530528203	[792]	[876,709,879,990]	4	hSpCas9	negative selection	6242247
110568992	110569015	10	+	27260156	CADOES1	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.9882791879019203	[444]	[186,289,167,188]	-9	hSpCas9	negative selection	6242248
110577888	110577911	10	+	27260156	CADOES1	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.286136629892884	[79]	[15,72,73,81]	-5	hSpCas9	negative selection	6242249
110575377	110575400	10	-	27260156	EWS502	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.04440296059512777	[576]	[528,465,617,781]	-1	hSpCas9	negative selection	6299245
110568946	110568969	10	-	27260156	EWS502	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.7344651814641606	[299]	[142,245,165,212]	-8	hSpCas9	negative selection	6299246
110575366	110575389	10	+	27260156	EWS502	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.2990376680684017	[206]	[7,82,59,28]	-9	hSpCas9	negative selection	6299247
110577850	110577873	10	+	27260156	EWS502	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.30221927929792003	[792]	[819,1106,1252,980]	5	hSpCas9	negative selection	6363498
110568992	110569015	10	+	27260156	EWS502	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.2492481733984662	[444]	[149,170,175,309]	-9	hSpCas9	negative selection	6363499
110577888	110577911	10	+	27260156	EWS502	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.0499358930113156	[79]	[40,56,33,29]	-9	hSpCas9	negative selection	6363500
110575377	110575400	10	-	27260156	EW8	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.4952645007619606	[576]	[304,277,328,410]	-7	hSpCas9	negative selection	6420496
110568946	110568969	10	-	27260156	EW8	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.05912224720217785	[299]	[343,191,124,301]	-1	hSpCas9	negative selection	6420497
110575366	110575389	10	+	27260156	EW8	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.7558617680934494	[206]	[40,26,75,48]	-9	hSpCas9	negative selection	6420498
110577850	110577873	10	+	27260156	EW8	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.3449257222393215	[792]	[1159,829,734,589]	6	hSpCas9	negative selection	6484749
110568992	110569015	10	+	27260156	EW8	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.5955243816528127	[444]	[183,205,217,342]	-8	hSpCas9	negative selection	6484750
110577888	110577911	10	+	27260156	EW8	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.6572541446532565	[79]	[21,9,21,27]	-9	hSpCas9	negative selection	6484751
110575377	110575400	10	-	27260156	CORL105	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.06715055043772111	[576]	[740,711,622,501]	-1	hSpCas9	negative selection	6541747
110568946	110568969	10	-	27260156	CORL105	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.16442415458796078	[299]	[253,390,288,311]	-3	hSpCas9	negative selection	6541748
110575366	110575389	10	+	27260156	CORL105	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.2682019511424454	[206]	[100,92,40,157]	-9	hSpCas9	negative selection	6541749
110577850	110577873	10	+	27260156	CORL105	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.12654685516006114	[792]	[1191,978,1132,775]	2	hSpCas9	negative selection	6606000
110568992	110569015	10	+	27260156	CORL105	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.9155026683671025	[444]	[236,262,298,307]	-9	hSpCas9	negative selection	6606001
110577888	110577911	10	+	27260156	CORL105	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.6390770125149752	[79]	[20,10,59,32]	-9	hSpCas9	negative selection	6606002
110575377	110575400	10	-	27260156	HS294T	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.21466328033149518	[576]	[173,175,231,187]	-3	hSpCas9	negative selection	6662998
110568946	110568969	10	-	27260156	HS294T	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.33086607125506007	[299]	[54,135,70,111]	-5	hSpCas9	negative selection	6662999
110575366	110575389	10	+	27260156	HS294T	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.7161481411806292	[206]	[18,23,24,30]	-9	hSpCas9	negative selection	6663000
110577850	110577873	10	+	27260156	HS294T	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	-0.010439654311917845	[792]	[260,277,326,365]	0	hSpCas9	negative selection	6727251
110568992	110569015	10	+	27260156	HS294T	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.232061771978266	[444]	[84,40,76,92]	-9	hSpCas9	negative selection	6727252
110577888	110577911	10	+	27260156	HS294T	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.3168948757696732	[79]	[19,6,9,11]	-9	hSpCas9	negative selection	6727253
110575377	110575400	10	-	27260156	HCC44	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.279067563109912	[576]	[971,721,860,648]	4	hSpCas9	negative selection	6784249
110568946	110568969	10	-	27260156	HCC44	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-1.0069746763912355	[299]	[83,120,184,281]	-8	hSpCas9	negative selection	6784250
110575366	110575389	10	+	27260156	HCC44	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.731485709978389	[206]	[99,63,61,57]	-9	hSpCas9	negative selection	6784251
110577850	110577873	10	+	27260156	HCC44	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.2750793977876912	[792]	[1113,1160,1115,942]	4	hSpCas9	negative selection	6848502
110568992	110569015	10	+	27260156	HCC44	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.0351793750682046	[444]	[285,274,284,143]	-8	hSpCas9	negative selection	6848503
110577888	110577911	10	+	27260156	HCC44	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.5730760907793497	[79]	[79,2,33,13]	-9	hSpCas9	negative selection	6848504
110575377	110575400	10	-	27260156	G402	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.13644784650389205	[576]	[717,397,594,835]	-2	hSpCas9	negative selection	6905500
110568946	110568969	10	-	27260156	G402	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.30163099511795166	[299]	[518,338,143,222]	-4	hSpCas9	negative selection	6905501
110575366	110575389	10	+	27260156	G402	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-3.614647654554748	[206]	[14,10,54,0]	-9	hSpCas9	negative selection	6905502
110577850	110577873	10	+	27260156	G402	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.47058278235904816	[792]	[1288,2024,983,1103]	6	hSpCas9	negative selection	6969753
110568992	110569015	10	+	27260156	G402	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8351548529974596	[444]	[759,148,249,122]	-7	hSpCas9	negative selection	6969754
110577888	110577911	10	+	27260156	G402	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.3987453799811043	[79]	[19,113,0,15]	-9	hSpCas9	negative selection	6969755
110575377	110575400	10	-	27260156	L33	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.23539790305383934	[576]	[573,274,484,702]	5	hSpCas9	negative selection	7026751
110568946	110568969	10	-	27260156	L33	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.13614751770116285	[299]	[211,144,228,390]	3	hSpCas9	negative selection	7026752
110575366	110575389	10	+	27260156	L33	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.5669861082498702	[206]	[84,25,46,55]	-9	hSpCas9	negative selection	7026753
110577850	110577873	10	+	27260156	L33	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	-0.08705941624170321	[792]	[746,319,509,647]	-2	hSpCas9	negative selection	7091004
110568992	110569015	10	+	27260156	L33	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.4147326644294619	[444]	[292,121,226,383]	-7	hSpCas9	negative selection	7091005
110577888	110577911	10	+	27260156	L33	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.3552391033327913	[79]	[48,13,36,107]	-7	hSpCas9	negative selection	7091006
110575377	110575400	10	-	27260156	K562	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.17850091005907445	[576]	[371,430,561,436]	-2	hSpCas9	negative selection	7148002
110568946	110568969	10	-	27260156	K562	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-1.2470465986525565	[299]	[174,23,130,117]	-8	hSpCas9	negative selection	7148003
110575366	110575389	10	+	27260156	K562	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-4.3365926503466845	[206]	[17,0,11,5]	-9	hSpCas9	negative selection	7148004
110577850	110577873	10	+	27260156	K562	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.29937158962081545	[792]	[672,1376,579,843]	4	hSpCas9	negative selection	7212255
110568992	110569015	10	+	27260156	K562	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8432943012388716	[444]	[263,353,248,43]	-7	hSpCas9	negative selection	7212256
110577888	110577911	10	+	27260156	K562	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.4461585460203463	[79]	[2,12,160,27]	-5	hSpCas9	negative selection	7212257
110575377	110575400	10	-	27260156	HT29	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.3482336369903528	[576]	[691,519,515,487]	-6	hSpCas9	negative selection	7269253
110568946	110568969	10	-	27260156	HT29	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.6100750485718663	[299]	[181,227,257,275]	-7	hSpCas9	negative selection	7269254
110575366	110575389	10	+	27260156	HT29	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.3796839986402576	[206]	[62,68,33,31]	-9	hSpCas9	negative selection	7269255
110577850	110577873	10	+	27260156	HT29	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.2164228150648333	[792]	[1111,1375,1107,921]	4	hSpCas9	negative selection	7333506
110568992	110569015	10	+	27260156	HT29	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.0482170718779755	[444]	[290,333,247,188]	-8	hSpCas9	negative selection	7333507
110577888	110577911	10	+	27260156	HT29	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-2.172386907033572	[79]	[30,33,1,20]	-9	hSpCas9	negative selection	7333508
110575377	110575400	10	-	27260156	MHHES1	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-1.054546948102175	[576]	[409,295,372,201]	-9	hSpCas9	negative selection	7390504
110568946	110568969	10	-	27260156	MHHES1	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.26884258912645065	[299]	[377,363,175,228]	-5	hSpCas9	negative selection	7390505
110575366	110575389	10	+	27260156	MHHES1	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.636055795861175	[206]	[102,173,224,102]	-8	hSpCas9	negative selection	7390506
110577850	110577873	10	+	27260156	MHHES1	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.07295514251541024	[792]	[1230,846,1094,656]	1	hSpCas9	negative selection	7454757
110568992	110569015	10	+	27260156	MHHES1	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.3601423992544102	[444]	[630,481,327,195]	-6	hSpCas9	negative selection	7454758
110577888	110577911	10	+	27260156	MHHES1	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-2.799155382924863	[79]	[16,13,17,4]	-9	hSpCas9	negative selection	7454759
110575377	110575400	10	-	27260156	MEWO	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.07419135249398262	[576]	[769,540,432]	1	hSpCas9	negative selection	7511755
110568946	110568969	10	-	27260156	MEWO	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.03585325457482391	[299]	[359,269,207]	-1	hSpCas9	negative selection	7511756
110575366	110575389	10	+	27260156	MEWO	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.951221418974977	[206]	[63,34,53]	-9	hSpCas9	negative selection	7511757
110577850	110577873	10	+	27260156	MEWO	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.2139359318006937	[792]	[888,820,876]	5	hSpCas9	negative selection	7576008
110568992	110569015	10	+	27260156	MEWO	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.7282224036939103	[444]	[314,296,153]	-9	hSpCas9	negative selection	7576009
110577888	110577911	10	+	27260156	MEWO	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.11757574255471237	[79]	[38,96,64]	-3	hSpCas9	negative selection	7576010
110575377	110575400	10	-	27260156	LNCAPCLONEFGC	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.47145168302033147	[576]	[380,376,480,283]	-6	hSpCas9	negative selection	7633006
110568946	110568969	10	-	27260156	LNCAPCLONEFGC	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.387421909391909	[299]	[301,187,110,214]	-6	hSpCas9	negative selection	7633007
110575366	110575389	10	+	27260156	LNCAPCLONEFGC	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.4766326357859356	[206]	[29,106,76,54]	-9	hSpCas9	negative selection	7633008
110577850	110577873	10	+	27260156	LNCAPCLONEFGC	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.36332668998012674	[792]	[1039,701,1118,875]	6	hSpCas9	negative selection	7697259
110568992	110569015	10	+	27260156	LNCAPCLONEFGC	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.9213690273526888	[444]	[121,362,171,179]	-8	hSpCas9	negative selection	7697260
110577888	110577911	10	+	27260156	LNCAPCLONEFGC	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.967301847527958	[79]	[75,28,36,5]	-8	hSpCas9	negative selection	7697261
110575377	110575400	10	-	27260156	PANC0327	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.07704542406812476	[576]	[624,360,733,472]	1	hSpCas9	negative selection	7754257
110568946	110568969	10	-	27260156	PANC0327	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.4142237049404668	[299]	[370,106,229,117]	-6	hSpCas9	negative selection	7754258
110575366	110575389	10	+	27260156	PANC0327	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.813332075470383	[206]	[25,99,64,9]	-9	hSpCas9	negative selection	7754259
110577850	110577873	10	+	27260156	PANC0327	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.5715956055733801	[792]	[1060,1248,834,1016]	8	hSpCas9	negative selection	7818510
110568992	110569015	10	+	27260156	PANC0327	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.9793164441827663	[444]	[241,118,268,185]	-8	hSpCas9	negative selection	7818511
110577888	110577911	10	+	27260156	PANC0327	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.17785723605215376	[79]	[8,138,42,45]	-3	hSpCas9	negative selection	7818512
110575377	110575400	10	-	27260156	NCIH2009	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.6523368436925114	[576]	[554,523,466]	-7	hSpCas9	negative selection	7875508
110568946	110568969	10	-	27260156	NCIH2009	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.41940595715931284	[299]	[399,247,309]	-5	hSpCas9	negative selection	7875509
110575366	110575389	10	+	27260156	NCIH2009	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-3.0348349665648255	[206]	[46,41,18]	-9	hSpCas9	negative selection	7875510
110577850	110577873	10	+	27260156	NCIH2009	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.3897739700355026	[792]	[1480,1296,1582]	5	hSpCas9	negative selection	7939761
110568992	110569015	10	+	27260156	NCIH2009	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.4520295613885876	[444]	[151,253,259]	-9	hSpCas9	negative selection	7939762
110577888	110577911	10	+	27260156	NCIH2009	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.8261162399898758	[79]	[23,32,35]	-9	hSpCas9	negative selection	7939763
110575377	110575400	10	-	27260156	NCIH1373	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.17373514203634333	[576]	[857,640,501,81]	-2	hSpCas9	negative selection	7996759
110568946	110568969	10	-	27260156	NCIH1373	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.07464779571901048	[299]	[440,501,280,46]	0	hSpCas9	negative selection	7996760
110575366	110575389	10	+	27260156	NCIH1373	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.2064634095403022	[206]	[29,161,99,23]	-8	hSpCas9	negative selection	7996761
110577850	110577873	10	+	27260156	NCIH1373	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.5865324771028316	[792]	[1771,987,1334,352]	6	hSpCas9	negative selection	8061012
110568992	110569015	10	+	27260156	NCIH1373	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.40983057294167174	[444]	[437,386,258,112]	-4	hSpCas9	negative selection	8061013
110577888	110577911	10	+	27260156	NCIH1373	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-4.122956541948184	[79]	[8,2,1,1]	-9	hSpCas9	negative selection	8061014
110575377	110575400	10	-	27260156	PATU8902	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-1.836686711714146	[576]	[256,209,108,368]	-9	hSpCas9	negative selection	8118010
110568946	110568969	10	-	27260156	PATU8902	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.33722268502029346	[299]	[574,689,566,228]	3	hSpCas9	negative selection	8118011
110575366	110575389	10	+	27260156	PATU8902	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.9806996720808234	[206]	[10,16,29,96]	-9	hSpCas9	negative selection	8118012
110577850	110577873	10	+	27260156	PATU8902	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.441783626241386	[792]	[1859,1415,1419,1281]	4	hSpCas9	negative selection	8182263
110568992	110569015	10	+	27260156	PATU8902	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.5854955749037423	[444]	[179,209,112,364]	-8	hSpCas9	negative selection	8182264
110577888	110577911	10	+	27260156	PATU8902	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-3.001663645891047	[79]	[3,41,2,8]	-9	hSpCas9	negative selection	8182265
110575377	110575400	10	-	27260156	PANC1	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.0693918685011406	[576]	[330,627,613,362]	-1	hSpCas9	negative selection	8239261
110568946	110568969	10	-	27260156	PANC1	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.5483101926030084	[299]	[229,343,45,122]	-7	hSpCas9	negative selection	8239262
110575366	110575389	10	+	27260156	PANC1	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.806223546727167	[206]	[9,19,40,28]	-9	hSpCas9	negative selection	8239263
110577850	110577873	10	+	27260156	PANC1	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.44504333653658257	[792]	[831,1491,719,788]	7	hSpCas9	negative selection	8303514
110568992	110569015	10	+	27260156	PANC1	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8920414273663703	[444]	[124,390,179,169]	-8	hSpCas9	negative selection	8303515
110577888	110577911	10	+	27260156	PANC1	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.10570138538556595	[79]	[163,20,54,11]	-2	hSpCas9	negative selection	8303516
110575377	110575400	10	-	27260156	PANC0813	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.4333373136606039	[576]	[499,531,463,509]	-6	hSpCas9	negative selection	8360512
110568946	110568969	10	-	27260156	PANC0813	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.6399692315122559	[299]	[244,162,285,212]	-7	hSpCas9	negative selection	8360513
110575366	110575389	10	+	27260156	PANC0813	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.801526759984533	[206]	[18,51,49,17]	-9	hSpCas9	negative selection	8360514
110577850	110577873	10	+	27260156	PANC0813	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.06872077215080141	[792]	[1042,1265,755,852]	1	hSpCas9	negative selection	8424765
110568992	110569015	10	+	27260156	PANC0813	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.9373344741267781	[444]	[262,155,327,339]	-8	hSpCas9	negative selection	8424766
110577888	110577911	10	+	27260156	PANC0813	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.9702511128641773	[79]	[76,6,52,56]	-8	hSpCas9	negative selection	8424767
110575377	110575400	10	-	27260156	RDES	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.41447903546622195	[576]	[313,532,514,680]	-6	hSpCas9	negative selection	8481763
110568946	110568969	10	-	27260156	RDES	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.548498477754446	[299]	[191,246,277,227]	-7	hSpCas9	negative selection	8481764
110575366	110575389	10	+	27260156	RDES	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.8815772090733749	[206]	[155,89,150,110]	-9	hSpCas9	negative selection	8481765
110577850	110577873	10	+	27260156	RDES	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.4112788131088031	[792]	[926,1145,1282,1587]	6	hSpCas9	negative selection	8546016
110568992	110569015	10	+	27260156	RDES	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8117360493828741	[444]	[209,300,298,377]	-8	hSpCas9	negative selection	8546017
110577888	110577911	10	+	27260156	RDES	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.3705383263969324	[79]	[53,64,74,96]	-6	hSpCas9	negative selection	8546018
110575377	110575400	10	-	27260156	PC3	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.1685114587662655	[576]	[458,441,1257,691]	4	hSpCas9	negative selection	8603014
110568946	110568969	10	-	27260156	PC3	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	0.006459973177355249	[299]	[194,438,336,248]	0	hSpCas9	negative selection	8603015
110575366	110575389	10	+	27260156	PC3	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.3688614568160322	[206]	[63,64,123,81]	-9	hSpCas9	negative selection	8603016
110577850	110577873	10	+	27260156	PC3	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.18363331624221235	[792]	[519,907,1536,960]	4	hSpCas9	negative selection	8667267
110568992	110569015	10	+	27260156	PC3	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.5039372696194124	[444]	[174,333,400,410]	-8	hSpCas9	negative selection	8667268
110577888	110577911	10	+	27260156	PC3	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.6886238211426963	[79]	[20,96,92,7]	-9	hSpCas9	negative selection	8667269
110575377	110575400	10	-	27260156	PATU8988T	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	0.2260485757324724	[576]	[857,626,437,688]	4	hSpCas9	negative selection	8724265
110568946	110568969	10	-	27260156	PATU8988T	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-1.0371771869500903	[299]	[172,151,105,134]	-9	hSpCas9	negative selection	8724266
110575366	110575389	10	+	27260156	PATU8988T	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-2.260013307204634	[206]	[21,51,30,64]	-9	hSpCas9	negative selection	8724267
110577850	110577873	10	+	27260156	PATU8988T	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.0765015142937816	[792]	[737,811,817,868]	1	hSpCas9	negative selection	8788518
110568992	110569015	10	+	27260156	PATU8988T	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.2434717251409357	[444]	[158,197,177,193]	-9	hSpCas9	negative selection	8788519
110577888	110577911	10	+	27260156	PATU8988T	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-3.464291307131953	[79]	[4,0,7,13]	-9	hSpCas9	negative selection	8788520
110575377	110575400	10	-	27260156	T47D	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.3313059600941743	[576]	[538,532,552,510]	-6	hSpCas9	negative selection	8845516
110568946	110568969	10	-	27260156	T47D	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.3429325472944793	[299]	[249,238,302,313]	-6	hSpCas9	negative selection	8845517
110575366	110575389	10	+	27260156	T47D	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.936671826696254	[206]	[52,67,34,96]	-9	hSpCas9	negative selection	8845518
110577850	110577873	10	+	27260156	T47D	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.15551955402780104	[792]	[959,907,1179,1076]	3	hSpCas9	negative selection	8909769
110568992	110569015	10	+	27260156	T47D	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.6751165954153626	[444]	[331,307,373,283]	-8	hSpCas9	negative selection	8909770
110577888	110577911	10	+	27260156	T47D	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.0582686182284684	[79]	[74,26,30,47]	-9	hSpCas9	negative selection	8909771
110575377	110575400	10	-	27260156	SU8686	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.36288365775658715	[576]	[325,374,600,511]	-6	hSpCas9	negative selection	8966767
110568946	110568969	10	-	27260156	SU8686	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.529181456350399	[299]	[190,185,215,239]	-7	hSpCas9	negative selection	8966768
110575366	110575389	10	+	27260156	SU8686	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.8527407620846772	[206]	[108,13,34,69]	-9	hSpCas9	negative selection	8966769
110577850	110577873	10	+	27260156	SU8686	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.25531032644951346	[792]	[937,791,885,1188]	4	hSpCas9	negative selection	9031020
110568992	110569015	10	+	27260156	SU8686	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-1.241905741671143	[444]	[191,105,278,178]	-9	hSpCas9	negative selection	9031021
110577888	110577911	10	+	27260156	SU8686	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.1673172143866557	[79]	[44,6,57,33]	-9	hSpCas9	negative selection	9031022
110575377	110575400	10	-	27260156	SKES1	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.22885829339571018	[576]	[591,427,587,370]	-5	hSpCas9	negative selection	9088018
110568946	110568969	10	-	27260156	SKES1	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.42763805793644927	[299]	[209,276,183,221]	-7	hSpCas9	negative selection	9088019
110575366	110575389	10	+	27260156	SKES1	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-1.1611452966950206	[206]	[96,161,96,28]	-9	hSpCas9	negative selection	9088020
110577850	110577873	10	+	27260156	SKES1	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.03632815025196845	[792]	[887,842,750,773]	0	hSpCas9	negative selection	9152271
110568992	110569015	10	+	27260156	SKES1	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8029676736944418	[444]	[178,287,305,236]	-9	hSpCas9	negative selection	9152272
110577888	110577911	10	+	27260156	SKES1	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.191705011375677	[79]	[73,65,1,9]	-9	hSpCas9	negative selection	9152273
110575377	110575400	10	-	27260156	TOV112D	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.07807146211092034	[576]	[385,637,495,673]	-1	hSpCas9	negative selection	9209269
110568946	110568969	10	-	27260156	TOV112D	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.3398634338265254	[299]	[209,258,273,209]	-6	hSpCas9	negative selection	9209270
110575366	110575389	10	+	27260156	TOV112D	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.8856839261311331	[206]	[150,66,81,139]	-9	hSpCas9	negative selection	9209271
110577850	110577873	10	+	27260156	TOV112D	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.16201412801102288	[792]	[1111,1067,765,675]	3	hSpCas9	negative selection	9273522
110568992	110569015	10	+	27260156	TOV112D	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.5122982978517061	[444]	[221,251,480,272]	-7	hSpCas9	negative selection	9273523
110577888	110577911	10	+	27260156	TOV112D	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.3461312122161124	[79]	[7,26,22,63]	-9	hSpCas9	negative selection	9273524
110575377	110575400	10	-	27260156	TC71	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.1762734515322979	[576]	[520,625,503,539]	-5	hSpCas9	negative selection	9330520
110568946	110568969	10	-	27260156	TC71	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.5469223479096922	[299]	[228,194,232,222]	-9	hSpCas9	negative selection	9330521
110575366	110575389	10	+	27260156	TC71	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.39999184951553257	[206]	[179,147,196,144]	-8	hSpCas9	negative selection	9330522
110577850	110577873	10	+	27260156	TC71	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.11906182387772346	[792]	[878,913,904,1000]	3	hSpCas9	negative selection	9394773
110568992	110569015	10	+	27260156	TC71	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.2825346005198981	[444]	[355,416,364,434]	-6	hSpCas9	negative selection	9394774
110577888	110577911	10	+	27260156	TC71	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-0.5298357936773583	[79]	[48,30,82,74]	-9	hSpCas9	negative selection	9394775
110575377	110575400	10	-	27260156	TC32	viability	AATAAAGCCAACCGCTGTTCTGG	SMC3	ENSG00000108055	-0.5724641774458427	[576]	[316,207,604,418]	-8	hSpCas9	negative selection	9451771
110568946	110568969	10	-	27260156	TC32	viability	CTCTGTAACTTCGAAAACCCTGG	SMC3	ENSG00000108055	-0.14379423466955088	[299]	[298,156,332,261]	-3	hSpCas9	negative selection	9451772
110575366	110575389	10	+	27260156	TC32	viability	GTCATCTTCGTCCAGAACAGCGG	SMC3	ENSG00000108055	-0.479815541580743	[206]	[108,111,124,219]	-7	hSpCas9	negative selection	9451773
110577850	110577873	10	+	27260156	TC32	viability	GTTTCACTTCGAAGAGTTATTGG	SMC3	ENSG00000108055	0.39486744374296523	[792]	[1064,752,1136,1006]	7	hSpCas9	negative selection	9516024
110568992	110569015	10	+	27260156	TC32	viability	AGTTCAAAACATAATGTGATTGG	SMC3	ENSG00000108055	-0.8787140582406954	[444]	[330,38,284,315]	-9	hSpCas9	negative selection	9516025
110577888	110577911	10	+	27260156	TC32	viability	GTATTTCTTAGACAAGAAGATGG	SMC3	ENSG00000108055	-1.6600680127006875	[79]	[46,0,17,32]	-9	hSpCas9	negative selection	9516026
110584180	110584203	10	+	27869803	HPAFII	viability after 27 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.02165643194241	[131]	[13,3,NaN]	-9	hSpCas9	negative selection	9536651
110589631	110589654	10	+	27869803	HPAFII	viability after 27 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.5492402262178426	[312]	[94,126,NaN]	-4	hSpCas9	negative selection	9536652
110590532	110590555	10	-	27869803	HPAFII	viability after 27 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-2.458972284344498	[385]	[19,50,NaN]	-8	hSpCas9	negative selection	9536653
110593165	110593188	10	+	27869803	HPAFII	viability after 27 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.13240024626420177	[117]	[139,7,NaN]	1	hSpCas9	negative selection	9536654
110598178	110598201	10	+	27869803	HPAFII	viability after 27 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.8269554710732459	[372]	[175,55,NaN]	-5	hSpCas9	negative selection	9536655
110599791	110599814	10	+	27869803	HPAFII	viability after 27 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.8926456187564505	[173]	[69,31,NaN]	-6	hSpCas9	negative selection	9536656
110584180	110584203	10	+	27869803	HPAFII	viability after 15 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.8186235593698543	[131]	[46,35,NaN]	-9	hSpCas9	negative selection	9619100
110589631	110589654	10	+	27869803	HPAFII	viability after 15 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.5204185883574042	[312]	[281,204,NaN]	-5	hSpCas9	negative selection	9619101
110590532	110590555	10	-	27869803	HPAFII	viability after 15 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-0.7288027894794682	[385]	[282,229,NaN]	-6	hSpCas9	negative selection	9619102
110593165	110593188	10	+	27869803	HPAFII	viability after 15 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.46419176121189776	[117]	[205,20,NaN]	-5	hSpCas9	negative selection	9619103
110598178	110598201	10	+	27869803	HPAFII	viability after 15 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.8393553542019772	[372]	[355,141,NaN]	-7	hSpCas9	negative selection	9619104
110599791	110599814	10	+	27869803	HPAFII	viability after 15 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.4070626777236492	[173]	[382,163,NaN]	5	hSpCas9	negative selection	9619105
110584180	110584203	10	+	27869803	ASPC1	viability after 36 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.486041742639229	[372]	[36,0,30]	-9	hSpCas9	negative selection	9701549
110589631	110589654	10	+	27869803	ASPC1	viability after 36 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	0.9510969847394377	[724]	[325,891,278]	8	hSpCas9	negative selection	9701550
110590532	110590555	10	-	27869803	ASPC1	viability after 36 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	0.4404803947683268	[1146]	[611,713,353]	4	hSpCas9	negative selection	9701551
110593165	110593188	10	+	27869803	ASPC1	viability after 36 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	0.8685595501889856	[322]	[643,39,27]	8	hSpCas9	negative selection	9701552
110598178	110598201	10	+	27869803	ASPC1	viability after 36 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.11077942795783516	[665]	[183,111,316]	-1	hSpCas9	negative selection	9701553
110599791	110599814	10	+	27869803	ASPC1	viability after 36 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.2212663186986784	[387]	[85,167,94]	-2	hSpCas9	negative selection	9701554
110584180	110584203	10	+	27869803	PATU8988S	viability after 35 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-3.7786618747560903	[272]	[12,2,NaN]	-9	hSpCas9	negative selection	9783998
110589631	110589654	10	+	27869803	PATU8988S	viability after 35 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-2.0595860939427957	[790]	[41,110,NaN]	-9	hSpCas9	negative selection	9783999
110590532	110590555	10	-	27869803	PATU8988S	viability after 35 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-1.477416099818158	[1025]	[104,191,NaN]	-8	hSpCas9	negative selection	9784000
110593165	110593188	10	+	27869803	PATU8988S	viability after 35 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-1.6614983175707903	[246]	[7,54,NaN]	-8	hSpCas9	negative selection	9784001
110598178	110598201	10	+	27869803	PATU8988S	viability after 35 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.4910393120819823	[661]	[14,79,NaN]	-9	hSpCas9	negative selection	9784002
110599791	110599814	10	+	27869803	PATU8988S	viability after 35 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.12442794440698668	[374]	[223,104,NaN]	1	hSpCas9	negative selection	9784003
110584180	110584203	10	+	27869803	PATU8988S	viability after 31 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-2.028588474114064	[272]	[27,24,NaN]	-9	hSpCas9	negative selection	9866447
110589631	110589654	10	+	27869803	PATU8988S	viability after 31 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.8548554833401485	[790]	[73,103,NaN]	-9	hSpCas9	negative selection	9866448
110590532	110590555	10	-	27869803	PATU8988S	viability after 31 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-1.6470261616279225	[1025]	[72,203,NaN]	-8	hSpCas9	negative selection	9866449
110593165	110593188	10	+	27869803	PATU8988S	viability after 31 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.43288235769676797	[246]	[68,77,NaN]	-5	hSpCas9	negative selection	9866450
110598178	110598201	10	+	27869803	PATU8988S	viability after 31 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-2.7194324663306104	[661]	[36,43,NaN]	-9	hSpCas9	negative selection	9866451
110599791	110599814	10	+	27869803	PATU8988S	viability after 31 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	0.2501667506413505	[374]	[183,169,NaN]	3	hSpCas9	negative selection	9866452
110584180	110584203	10	+	27869803	HPAFII	viability after 35 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.5569568635235649	[131]	[33,9,NaN]	-7	hSpCas9	negative selection	9948896
110589631	110589654	10	+	27869803	HPAFII	viability after 35 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-1.0548349121334173	[312]	[32,124,NaN]	-5	hSpCas9	negative selection	9948897
110590532	110590555	10	-	27869803	HPAFII	viability after 35 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-2.1786768231585008	[385]	[13,75,NaN]	-8	hSpCas9	negative selection	9948898
110593165	110593188	10	+	27869803	HPAFII	viability after 35 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.32740129793364314	[117]	[88,0,NaN]	-2	hSpCas9	negative selection	9948899
110598178	110598201	10	+	27869803	HPAFII	viability after 35 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-0.402308634588078	[372]	[132,153,NaN]	-2	hSpCas9	negative selection	9948900
110599791	110599814	10	+	27869803	HPAFII	viability after 35 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.38070626712117395	[173]	[85,46,NaN]	-2	hSpCas9	negative selection	9948901
110584180	110584203	10	+	27869803	HPAFII	viability after 31 days	TAGATTGGCTCAAGCTACCCAGG	SMC3	ENSG00000108055	-1.5221232316795221	[131]	[9,42,NaN]	-7	hSpCas9	negative selection	10031345
110589631	110589654	10	+	27869803	HPAFII	viability after 31 days	CAAAGCTCGAGTAGAAGAACTGG	SMC3	ENSG00000108055	-0.9806826626365233	[312]	[66,112,NaN]	-6	hSpCas9	negative selection	10031346
110590532	110590555	10	-	27869803	HPAFII	viability after 31 days	TCCACGCATGTGTAGAAAGCTGG	SMC3	ENSG00000108055	-2.4276570023965776	[385]	[34,45,NaN]	-8	hSpCas9	negative selection	10031347
110593165	110593188	10	+	27869803	HPAFII	viability after 31 days	CATGGAAGTTTCAACCCAGCTGG	SMC3	ENSG00000108055	-0.396170875434551	[117]	[90,5,NaN]	-3	hSpCas9	negative selection	10031348
110598178	110598201	10	+	27869803	HPAFII	viability after 31 days	AACAGATCGAGACCCAGCAAAGG	SMC3	ENSG00000108055	-1.0767692555318449	[372]	[126,68,NaN]	-6	hSpCas9	negative selection	10031349
110599791	110599814	10	+	27869803	HPAFII	viability after 31 days	TGAGATTCGTCAACTTCAGCAGG	SMC3	ENSG00000108055	-0.39442069119444767	[173]	[91,54,NaN]	-3	hSpCas9	negative selection	10031350
110583463	110583486	10	+	28162770	P31FUJ	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-3.3811940443070494	[398]	[44]	-9	hSpCas9	negative selection	10238952
110578641	110578664	10	+	28162770	P31FUJ	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.6318459426907352	[66]	[121]	7	hSpCas9	negative selection	10238953
110582621	110582644	10	+	28162770	P31FUJ	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.392673541192768	[142]	[0]	-9	hSpCas9	negative selection	10238954
110601028	110601051	10	+	28162770	P31FUJ	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-0.8848789009940718	[10]	[6]	-6	hSpCas9	negative selection	10238955
110601759	110601782	10	+	28162770	P31FUJ	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.8019107539346977	[180]	[60]	-8	hSpCas9	negative selection	10238956
110582023	110582046	10	+	28162770	P31FUJ	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.083658765108569	[100]	[13]	-9	hSpCas9	negative selection	10238957
110583488	110583511	10	+	28162770	P31FUJ	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-6.320265045664717	[67]	[0]	-9	hSpCas9	negative selection	10238958
110583931	110583954	10	+	28162770	P31FUJ	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-5.625119627193138	[41]	[0]	-9	hSpCas9	negative selection	10238959
110593188	110593211	10	-	28162770	P31FUJ	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-2.0104097830779306	[143]	[41]	-8	hSpCas9	negative selection	10238960
110599707	110599730	10	+	28162770	P31FUJ	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.6086691064125447	[108]	[41]	-7	hSpCas9	negative selection	10238961
110583463	110583486	10	+	28162770	TF1	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10408318
110578641	110578664	10	+	28162770	TF1	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10408319
110582621	110582644	10	+	28162770	TF1	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408320
110601028	110601051	10	+	28162770	TF1	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408321
110601759	110601782	10	+	28162770	TF1	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10408322
110582023	110582046	10	+	28162770	TF1	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10408323
110583488	110583511	10	+	28162770	TF1	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408324
110583931	110583954	10	+	28162770	TF1	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10408325
110593188	110593211	10	-	28162770	TF1	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10408326
110599707	110599730	10	+	28162770	TF1	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10408327
110583463	110583486	10	+	28162770	SKM1	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-4.044394119358453	[111]	[11]	-9	hSpCas9	negative selection	10577684
110578641	110578664	10	+	28162770	SKM1	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.26560834949762	[16]	[24]	-2	hSpCas9	negative selection	10577685
110582621	110582644	10	+	28162770	SKM1	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-6.069929211465591	[37]	[0]	-9	hSpCas9	negative selection	10577686
110601028	110601051	10	+	28162770	SKM1	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10577687
110601759	110601782	10	+	28162770	SKM1	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-2.2667865406949015	[48]	[17]	-8	hSpCas9	negative selection	10577688
110582023	110582046	10	+	28162770	SKM1	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.184571777406714	[35]	[6]	-9	hSpCas9	negative selection	10577689
110583488	110583511	10	+	28162770	SKM1	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.406964198743162	[20]	[6]	-8	hSpCas9	negative selection	10577690
110583931	110583954	10	+	28162770	SKM1	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10577691
110593188	110593211	10	-	28162770	SKM1	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-2.484966710744435	[37]	[11]	-9	hSpCas9	negative selection	10577692
110599707	110599730	10	+	28162770	SKM1	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.46585788779673	[24]	[15]	-7	hSpCas9	negative selection	10577693
110583463	110583486	10	+	28162770	SKM1	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-4.044394119358453	[111]	[11]	-9	hSpCas9	negative selection	10747050
110578641	110578664	10	+	28162770	SKM1	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.26560834949762	[16]	[24]	-2	hSpCas9	negative selection	10747051
110582621	110582644	10	+	28162770	SKM1	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-6.069929211465591	[37]	[0]	-9	hSpCas9	negative selection	10747052
110601028	110601051	10	+	28162770	SKM1	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10747053
110601759	110601782	10	+	28162770	SKM1	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-2.2667865406949015	[48]	[17]	-8	hSpCas9	negative selection	10747054
110582023	110582046	10	+	28162770	SKM1	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.184571777406714	[35]	[6]	-9	hSpCas9	negative selection	10747055
110583488	110583511	10	+	28162770	SKM1	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.406964198743162	[20]	[6]	-8	hSpCas9	negative selection	10747056
110583931	110583954	10	+	28162770	SKM1	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-4.143929792909368	[9]	[0]	-9	hSpCas9	negative selection	10747057
110593188	110593211	10	-	28162770	SKM1	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-2.484966710744435	[37]	[11]	-9	hSpCas9	negative selection	10747058
110599707	110599730	10	+	28162770	SKM1	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.46585788779673	[24]	[15]	-7	hSpCas9	negative selection	10747059
110583463	110583486	10	+	28162770	PL21	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-4.081558635609509	[388]	[9]	-9	hSpCas9	negative selection	10916416
110578641	110578664	10	+	28162770	PL21	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.6578413806382519	[57]	[15]	-4	hSpCas9	negative selection	10916417
110582621	110582644	10	+	28162770	PL21	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-2.9874873886864513	[163]	[8]	-9	hSpCas9	negative selection	10916418
110601028	110601051	10	+	28162770	PL21	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-3.0477878989542657	[18]	[0]	-9	hSpCas9	negative selection	10916419
110601759	110601782	10	+	28162770	PL21	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.9345099122054614	[201]	[22]	-8	hSpCas9	negative selection	10916420
110582023	110582046	10	+	28162770	PL21	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.310822304788059	[113]	[4]	-9	hSpCas9	negative selection	10916421
110583488	110583511	10	+	28162770	PL21	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.360575339985159	[58]	[4]	-8	hSpCas9	negative selection	10916422
110583931	110583954	10	+	28162770	PL21	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-0.6072153075682842	[13]	[3]	-4	hSpCas9	negative selection	10916423
110593188	110593211	10	-	28162770	PL21	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-3.79986038551068	[95]	[2]	-9	hSpCas9	negative selection	10916424
110599707	110599730	10	+	28162770	PL21	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-2.5141059031768025	[104]	[7]	-9	hSpCas9	negative selection	10916425
110583463	110583486	10	+	28162770	P31FUJ	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-3.3811940443070494	[398]	[44]	-9	hSpCas9	negative selection	11085782
110578641	110578664	10	+	28162770	P31FUJ	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.6318459426907352	[66]	[121]	7	hSpCas9	negative selection	11085783
110582621	110582644	10	+	28162770	P31FUJ	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.392673541192768	[142]	[0]	-9	hSpCas9	negative selection	11085784
110601028	110601051	10	+	28162770	P31FUJ	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-0.8848789009940718	[10]	[6]	-6	hSpCas9	negative selection	11085785
110601759	110601782	10	+	28162770	P31FUJ	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.8019107539346977	[180]	[60]	-8	hSpCas9	negative selection	11085786
110582023	110582046	10	+	28162770	P31FUJ	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.083658765108569	[100]	[13]	-9	hSpCas9	negative selection	11085787
110583488	110583511	10	+	28162770	P31FUJ	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-6.320265045664717	[67]	[0]	-9	hSpCas9	negative selection	11085788
110583931	110583954	10	+	28162770	P31FUJ	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-5.625119627193138	[41]	[0]	-9	hSpCas9	negative selection	11085789
110593188	110593211	10	-	28162770	P31FUJ	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-2.0104097830779306	[143]	[41]	-8	hSpCas9	negative selection	11085790
110599707	110599730	10	+	28162770	P31FUJ	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.6086691064125447	[108]	[41]	-7	hSpCas9	negative selection	11085791
110583463	110583486	10	+	28162770	OCIAML5	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-5.606954073027465	[188]	[6]	-9	hSpCas9	negative selection	11255148
110578641	110578664	10	+	28162770	OCIAML5	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-1.0661913762168445	[57]	[49]	-6	hSpCas9	negative selection	11255149
110582621	110582644	10	+	28162770	OCIAML5	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.770929808138591	[120]	[0]	-9	hSpCas9	negative selection	11255150
110601028	110601051	10	+	28162770	OCIAML5	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-4.552506289005089	[12]	[0]	-9	hSpCas9	negative selection	11255151
110601759	110601782	10	+	28162770	OCIAML5	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-0.9555711466178569	[129]	[120]	-5	hSpCas9	negative selection	11255152
110582023	110582046	10	+	28162770	OCIAML5	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-2.437029071585153	[50]	[16]	-8	hSpCas9	negative selection	11255153
110583488	110583511	10	+	28162770	OCIAML5	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.6041390574204115	[63]	[18]	-8	hSpCas9	negative selection	11255154
110583931	110583954	10	+	28162770	OCIAML5	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-0.7696044106720241	[16]	[17]	-5	hSpCas9	negative selection	11255155
110593188	110593211	10	-	28162770	OCIAML5	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-5.466776414979205	[48]	[1]	-9	hSpCas9	negative selection	11255156
110599707	110599730	10	+	28162770	OCIAML5	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.4561378945328576	[75]	[49]	-7	hSpCas9	negative selection	11255157
110583463	110583486	10	+	28162770	EOL1	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-1.7841228756276628	[790]	[120]	-8	hSpCas9	negative selection	11424514
110578641	110578664	10	+	28162770	EOL1	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.31686519434929505	[95]	[62]	3	hSpCas9	negative selection	11424515
110582621	110582644	10	+	28162770	EOL1	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-3.5702169201790435	[247]	[10]	-9	hSpCas9	negative selection	11424516
110601028	110601051	10	+	28162770	EOL1	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-1.1909294458494015	[12]	[2]	-7	hSpCas9	negative selection	11424517
110601759	110601782	10	+	28162770	EOL1	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	0.2855806158168447	[312]	[200]	2	hSpCas9	negative selection	11424518
110582023	110582046	10	+	28162770	EOL1	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.6827825421790763	[194]	[7]	-9	hSpCas9	negative selection	11424519
110583488	110583511	10	+	28162770	EOL1	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.1839766852076345	[68]	[7]	-8	hSpCas9	negative selection	11424520
110583931	110583954	10	+	28162770	EOL1	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-0.9735726144102519	[40]	[10]	-6	hSpCas9	negative selection	11424521
110593188	110593211	10	-	28162770	EOL1	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-1.1909294458494013	[155]	[35]	-7	hSpCas9	negative selection	11424522
110599707	110599730	10	+	28162770	EOL1	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.4637228181455237	[88]	[16]	-7	hSpCas9	negative selection	11424523
110583463	110583486	10	+	28162770	MOLM13	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-3.7774174317398708	[549]	[28]	-9	hSpCas9	negative selection	11593880
110578641	110578664	10	+	28162770	MOLM13	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-1.4848049036770647	[119]	[30]	-6	hSpCas9	negative selection	11593881
110582621	110582644	10	+	28162770	MOLM13	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.444999954685383	[240]	[0]	-9	hSpCas9	negative selection	11593882
110601028	110601051	10	+	28162770	MOLM13	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-4.232550336596514	[25]	[0]	-9	hSpCas9	negative selection	11593883
110601759	110601782	10	+	28162770	MOLM13	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	0.15905128609766023	[191]	[154]	1	hSpCas9	negative selection	11593884
110582023	110582046	10	+	28162770	MOLM13	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-5.269076212621627	[159]	[2]	-9	hSpCas9	negative selection	11593885
110583488	110583511	10	+	28162770	MOLM13	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-5.532110618455421	[63]	[0]	-9	hSpCas9	negative selection	11593886
110583931	110583954	10	+	28162770	MOLM13	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-5.576504737813875	[65]	[0]	-9	hSpCas9	negative selection	11593887
110593188	110593211	10	-	28162770	MOLM13	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-7.260031073018621	[211]	[0]	-9	hSpCas9	negative selection	11593888
110599707	110599730	10	+	28162770	MOLM13	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-5.204535960426917	[152]	[2]	-9	hSpCas9	negative selection	11593889
110583463	110583486	10	+	28162770	HEL	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-6.360076183606697	[512]	[3]	-9	hSpCas9	negative selection	11763246
110578641	110578664	10	+	28162770	HEL	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.3572611679996429	[81]	[40]	-2	hSpCas9	negative selection	11763247
110582621	110582644	10	+	28162770	HEL	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-1.6556024425693896	[181]	[36]	-7	hSpCas9	negative selection	11763248
110601028	110601051	10	+	28162770	HEL	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-3.2641517636081616	[14]	[0]	-9	hSpCas9	negative selection	11763249
110601759	110601782	10	+	28162770	HEL	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-2.561133501365293	[257]	[27]	-8	hSpCas9	negative selection	11763250
110582023	110582046	10	+	28162770	HEL	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-3.079727192470734	[131]	[9]	-9	hSpCas9	negative selection	11763251
110583488	110583511	10	+	28162770	HEL	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.2152421631272152	[57]	[7]	-8	hSpCas9	negative selection	11763252
110583931	110583954	10	+	28162770	HEL	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-4.1646160900572475	[55]	[1]	-9	hSpCas9	negative selection	11763253
110593188	110593211	10	-	28162770	HEL	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-3.1457570628059313	[151]	[10]	-9	hSpCas9	negative selection	11763254
110599707	110599730	10	+	28162770	HEL	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-0.23657968557717968	[148]	[80]	-2	hSpCas9	negative selection	11763255
110583463	110583486	10	+	28162770	MV411	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-2.7525624492172245	[415]	[51]	-9	hSpCas9	negative selection	11932612
110578641	110578664	10	+	28162770	MV411	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.3563719223359394	[50]	[54]	3	hSpCas9	negative selection	11932613
110582621	110582644	10	+	28162770	MV411	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-6.659453044825743	[119]	[0]	-9	hSpCas9	negative selection	11932614
110601028	110601051	10	+	28162770	MV411	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-3.337524949938381	[23]	[1]	-9	hSpCas9	negative selection	11932615
110601759	110601782	10	+	28162770	MV411	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.3302201493151475	[196]	[65]	-7	hSpCas9	negative selection	11932616
110582023	110582046	10	+	28162770	MV411	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-1.0645064555319648	[71]	[28]	-6	hSpCas9	negative selection	11932617
110583488	110583511	10	+	28162770	MV411	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.5133747853377986	[60]	[8]	-8	hSpCas9	negative selection	11932618
110583931	110583954	10	+	28162770	MV411	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-1.2719366083108046	[42]	[14]	-7	hSpCas9	negative selection	11932619
110593188	110593211	10	-	28162770	MV411	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-1.916949267118107	[129]	[28]	-8	hSpCas9	negative selection	11932620
110599707	110599730	10	+	28162770	MV411	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-2.840025290467564	[67]	[7]	-9	hSpCas9	negative selection	11932621
110583463	110583486	10	+	28162770	MONOMAC1	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-2.1392161926712117	[268]	[69]	-9	hSpCas9	negative selection	12101978
110578641	110578664	10	+	28162770	MONOMAC1	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	-0.6918015388091316	[30]	[21]	-5	hSpCas9	negative selection	12101979
110582621	110582644	10	+	28162770	MONOMAC1	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-5.0918546103674975	[118]	[3]	-9	hSpCas9	negative selection	12101980
110601028	110601051	10	+	28162770	MONOMAC1	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-0.19703684705955382	[5]	[5]	-2	hSpCas9	negative selection	12101981
110601759	110601782	10	+	28162770	MONOMAC1	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-0.2937128664712274	[107]	[100]	-3	hSpCas9	negative selection	12101982
110582023	110582046	10	+	28162770	MONOMAC1	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-0.8541491335365452	[81]	[51]	-6	hSpCas9	negative selection	12101983
110583488	110583511	10	+	28162770	MONOMAC1	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-2.284499688309893	[33]	[7]	-9	hSpCas9	negative selection	12101984
110583931	110583954	10	+	28162770	MONOMAC1	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-1.0450337536145038	[26]	[14]	-7	hSpCas9	negative selection	12101985
110593188	110593211	10	-	28162770	MONOMAC1	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-1.4358237066466704	[58]	[24]	-8	hSpCas9	negative selection	12101986
110599707	110599730	10	+	28162770	MONOMAC1	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-0.9984911676774737	[60]	[34]	-7	hSpCas9	negative selection	12101987
110583463	110583486	10	+	28162770	OCIAML2	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-3.494476567196529	[60]	[29]	-9	hSpCas9	negative selection	12271344
110578641	110578664	10	+	28162770	OCIAML2	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	0.9444076740366827	[8]	[95]	8	hSpCas9	negative selection	12271345
110582621	110582644	10	+	28162770	OCIAML2	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-7.22551732740563	[26]	[0]	-9	hSpCas9	negative selection	12271346
110601028	110601051	10	+	28162770	OCIAML2	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-5.0555923259633175	[5]	[0]	-9	hSpCas9	negative selection	12271347
110601759	110601782	10	+	28162770	OCIAML2	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.3857409276556483	[32]	[69]	-7	hSpCas9	negative selection	12271348
110582023	110582046	10	+	28162770	OCIAML2	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-2.4706298252421615	[10]	[10]	-8	hSpCas9	negative selection	12271349
110583488	110583511	10	+	28162770	OCIAML2	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-4.277984747299765	[6]	[1]	-9	hSpCas9	negative selection	12271350
110583931	110583954	10	+	28162770	OCIAML2	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-4.930061443879459	[10]	[1]	-9	hSpCas9	negative selection	12271351
110593188	110593211	10	-	28162770	OCIAML2	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-3.6770807027095875	[29]	[12]	-9	hSpCas9	negative selection	12271352
110599707	110599730	10	+	28162770	OCIAML2	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-0.923142029939668	[12]	[37]	-6	hSpCas9	negative selection	12271353
110583463	110583486	10	+	28162770	OCIAML3	viability	GACAAGAGCAGATTAAGCAGAGG	SMC3	ENSG00000108055	-2.7474821209858815	[108]	[48]	-9	hSpCas9	negative selection	12440710
110578641	110578664	10	+	28162770	OCIAML3	viability	ATGAACCTCCTTGAAAGCGCTGG	SMC3	ENSG00000108055	1.5243870604780672	[18]	[164]	9	hSpCas9	negative selection	12440711
110582621	110582644	10	+	28162770	OCIAML3	viability	GGATGCAAGAGATAAAATGGAGG	SMC3	ENSG00000108055	-4.401362562381768	[27]	[3]	-9	hSpCas9	negative selection	12440712
110601028	110601051	10	+	28162770	OCIAML3	viability	AATGAGCTGAGAGAGACAGAAGG	SMC3	ENSG00000108055	-3.5940076403241634	[3]	[0]	-9	hSpCas9	negative selection	12440713
110601759	110601782	10	+	28162770	OCIAML3	viability	GAAAAGATGACAAATCGGCAAGG	SMC3	ENSG00000108055	-1.8503473935839487	[42]	[35]	-8	hSpCas9	negative selection	12440714
110582023	110582046	10	+	28162770	OCIAML3	viability	GGATAAAATGAGACGAGCCCTGG	SMC3	ENSG00000108055	-1.1085808131539212	[14]	[20]	-7	hSpCas9	negative selection	12440715
110583488	110583511	10	+	28162770	OCIAML3	viability	TAAGTTGGAGCTTAAAGCCAAGG	SMC3	ENSG00000108055	-3.3595423866871403	[16]	[4]	-9	hSpCas9	negative selection	12440716
110583931	110583954	10	+	28162770	OCIAML3	viability	GTGAAAGAGAAAGAAGAACGAGG	SMC3	ENSG00000108055	-2.1345760216868657	[15]	[10]	-8	hSpCas9	negative selection	12440717
110593188	110593211	10	-	28162770	OCIAML3	viability	ACAGTCCATAGTGAAAGCACGGG	SMC3	ENSG00000108055	-3.594007640324164	[23]	[5]	-9	hSpCas9	negative selection	12440718
110599707	110599730	10	+	28162770	OCIAML3	viability	AGAGTCATTGAAAGCAGAACTGG	SMC3	ENSG00000108055	-1.0704456842671504	[15]	[22]	-6	hSpCas9	negative selection	12440719