Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6606
• Symbol: SMN1
• Description: survival of motor neuron 1, telomeric

DataSource: http://genomecrispr.dkfz.de/#!/results/SMN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.4803498892357139	[36]	[9]	-7	hSpCas9	negative selection	152223
70925101	70925124	5	+	26472758	Jiyoye	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.4803498892357139	[36]	[9]	-7	hSpCas9	negative selection	152224
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	-0.3297902126603328	[234]	[140]	-2	hSpCas9	negative selection	152227
70941438	70941461	5	-	26472758	Jiyoye	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	-0.3297902126603328	[234]	[140]	-2	hSpCas9	negative selection	152228
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.293264336635219	[129]	[39]	-7	hSpCas9	negative selection	152233
70946078	70946101	5	-	26472758	Jiyoye	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.293264336635219	[129]	[39]	-7	hSpCas9	negative selection	152236
70942438	70942461	5	+	26472758	Jiyoye	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.5903855730427092	[590]	[147]	-8	hSpCas9	negative selection	152240
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-1.5903855730427092	[590]	[147]	-8	hSpCas9	negative selection	152241
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.146626187728822	[228]	[38]	-8	hSpCas9	negative selection	152244
70942808	70942831	5	-	26472758	Jiyoye	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.146626187728822	[228]	[38]	-8	hSpCas9	negative selection	152246
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-0.9605564029946136	[159]	[61]	-6	hSpCas9	negative selection	152250
70925166	70925189	5	-	26472758	Jiyoye	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.9605564029946136	[159]	[61]	-6	hSpCas9	negative selection	152251
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-3.038135128886771	[304]	[27]	-9	hSpCas9	negative selection	152253
70925152	70925175	5	+	26472758	Jiyoye	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-3.038135128886771	[304]	[27]	-9	hSpCas9	negative selection	152254
70942454	70942477	5	+	26472758	Jiyoye	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.8283126974422579	[331]	[140]	-5	hSpCas9	negative selection	152259
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-0.8283126974422579	[331]	[140]	-5	hSpCas9	negative selection	152260
70942849	70942872	5	+	26472758	Jiyoye	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.951278589406603	[199]	[77]	-6	hSpCas9	negative selection	152264
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.951278589406603	[199]	[77]	-6	hSpCas9	negative selection	152265
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.201198505825335	[496]	[162]	-7	hSpCas9	negative selection	152267
70925113	70925136	5	+	26472758	Jiyoye	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.201198505825335	[496]	[162]	-7	hSpCas9	negative selection	152268
70925101	70925124	5	+	26472758	Jiyoye	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.4803498892357139	[36]	[9]	-7	hSpCas9	negative selection	152272
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.4803498892357139	[36]	[9]	-7	hSpCas9	negative selection	152275
70941438	70941461	5	-	26472758	Jiyoye	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	-0.3297902126603328	[234]	[140]	-2	hSpCas9	negative selection	152278
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	-0.3297902126603328	[234]	[140]	-2	hSpCas9	negative selection	152281
70946078	70946101	5	-	26472758	Jiyoye	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.293264336635219	[129]	[39]	-7	hSpCas9	negative selection	152284
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.293264336635219	[129]	[39]	-7	hSpCas9	negative selection	152285
70942438	70942461	5	+	26472758	Jiyoye	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.5903855730427092	[590]	[147]	-8	hSpCas9	negative selection	152287
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-1.5903855730427092	[590]	[147]	-8	hSpCas9	negative selection	152288
70942808	70942831	5	-	26472758	Jiyoye	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.146626187728822	[228]	[38]	-8	hSpCas9	negative selection	152293
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.146626187728822	[228]	[38]	-8	hSpCas9	negative selection	152295
70925166	70925189	5	-	26472758	Jiyoye	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.9605564029946136	[159]	[61]	-6	hSpCas9	negative selection	152298
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	Jiyoye	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-0.9605564029946136	[159]	[61]	-6	hSpCas9	negative selection	152301
70925152	70925175	5	+	26472758	Jiyoye	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-3.038135128886771	[304]	[27]	-9	hSpCas9	negative selection	152302
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-3.038135128886771	[304]	[27]	-9	hSpCas9	negative selection	152305
70942454	70942477	5	+	26472758	Jiyoye	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.8283126974422579	[331]	[140]	-5	hSpCas9	negative selection	152307
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-0.8283126974422579	[331]	[140]	-5	hSpCas9	negative selection	152308
70942849	70942872	5	+	26472758	Jiyoye	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.951278589406603	[199]	[77]	-6	hSpCas9	negative selection	152313
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.951278589406603	[199]	[77]	-6	hSpCas9	negative selection	152314
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	Jiyoye	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.201198505825335	[496]	[162]	-7	hSpCas9	negative selection	152319
70925113	70925136	5	+	26472758	Jiyoye	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.201198505825335	[496]	[162]	-7	hSpCas9	negative selection	152320
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.7564493825045826	[352,353]	[59,39]	-8	hSpCas9	negative selection	343341
70925101	70925124	5	+	26472758	KBM7	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.7564493825045826	[352,353]	[59,39]	-8	hSpCas9	negative selection	343342
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.6995068272966695	[838,594]	[632,457]	7	hSpCas9	negative selection	343345
70941438	70941461	5	-	26472758	KBM7	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.6995068272966695	[838,594]	[632,457]	7	hSpCas9	negative selection	343346
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-0.8476123762739002	[692,501]	[100,201]	-6	hSpCas9	negative selection	343351
70946078	70946101	5	-	26472758	KBM7	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.8476123762739002	[692,501]	[100,201]	-6	hSpCas9	negative selection	343354
70942438	70942461	5	+	26472758	KBM7	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-2.101023317892249	[1995,1431]	[211,161]	-8	hSpCas9	negative selection	343358
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-2.101023317892249	[1995,1431]	[211,161]	-8	hSpCas9	negative selection	343359
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.856312399732054	[552,420]	[24,36]	-9	hSpCas9	negative selection	343362
70942808	70942831	5	-	26472758	KBM7	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.856312399732054	[552,420]	[24,36]	-9	hSpCas9	negative selection	343364
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-0.18157442678743302	[586,404]	[291,122]	-2	hSpCas9	negative selection	343368
70925166	70925189	5	-	26472758	KBM7	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.18157442678743302	[586,404]	[291,122]	-2	hSpCas9	negative selection	343369
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.1591820085396374	[1018,810]	[184,196]	-7	hSpCas9	negative selection	343371
70925152	70925175	5	+	26472758	KBM7	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.1591820085396374	[1018,810]	[184,196]	-7	hSpCas9	negative selection	343372
70942454	70942477	5	+	26472758	KBM7	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.0685934055564	[1850,1707]	[394,402]	-7	hSpCas9	negative selection	343377
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-1.0685934055564	[1850,1707]	[394,402]	-7	hSpCas9	negative selection	343378
70942849	70942872	5	+	26472758	KBM7	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.2826513672111365	[567,459]	[253,146]	-3	hSpCas9	negative selection	343382
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.2826513672111365	[567,459]	[253,146]	-3	hSpCas9	negative selection	343383
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.566712441633126	[2458,2409]	[370,402]	-8	hSpCas9	negative selection	343385
70925113	70925136	5	+	26472758	KBM7	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.566712441633126	[2458,2409]	[370,402]	-8	hSpCas9	negative selection	343386
70925101	70925124	5	+	26472758	KBM7	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.7564493825045826	[352,353]	[59,39]	-8	hSpCas9	negative selection	343390
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.7564493825045826	[352,353]	[59,39]	-8	hSpCas9	negative selection	343393
70941438	70941461	5	-	26472758	KBM7	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.6995068272966695	[838,594]	[632,457]	7	hSpCas9	negative selection	343396
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.6995068272966695	[838,594]	[632,457]	7	hSpCas9	negative selection	343399
70946078	70946101	5	-	26472758	KBM7	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.8476123762739002	[692,501]	[100,201]	-6	hSpCas9	negative selection	343402
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-0.8476123762739002	[692,501]	[100,201]	-6	hSpCas9	negative selection	343403
70942438	70942461	5	+	26472758	KBM7	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-2.101023317892249	[1995,1431]	[211,161]	-8	hSpCas9	negative selection	343405
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-2.101023317892249	[1995,1431]	[211,161]	-8	hSpCas9	negative selection	343406
70942808	70942831	5	-	26472758	KBM7	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.856312399732054	[552,420]	[24,36]	-9	hSpCas9	negative selection	343411
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.856312399732054	[552,420]	[24,36]	-9	hSpCas9	negative selection	343413
70925166	70925189	5	-	26472758	KBM7	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.18157442678743302	[586,404]	[291,122]	-2	hSpCas9	negative selection	343416
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	KBM7	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-0.18157442678743302	[586,404]	[291,122]	-2	hSpCas9	negative selection	343419
70925152	70925175	5	+	26472758	KBM7	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.1591820085396374	[1018,810]	[184,196]	-7	hSpCas9	negative selection	343420
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.1591820085396374	[1018,810]	[184,196]	-7	hSpCas9	negative selection	343423
70942454	70942477	5	+	26472758	KBM7	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.0685934055564	[1850,1707]	[394,402]	-7	hSpCas9	negative selection	343425
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-1.0685934055564	[1850,1707]	[394,402]	-7	hSpCas9	negative selection	343426
70942849	70942872	5	+	26472758	KBM7	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.2826513672111365	[567,459]	[253,146]	-3	hSpCas9	negative selection	343431
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.2826513672111365	[567,459]	[253,146]	-3	hSpCas9	negative selection	343432
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	KBM7	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.566712441633126	[2458,2409]	[370,402]	-8	hSpCas9	negative selection	343437
70925113	70925136	5	+	26472758	KBM7	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.566712441633126	[2458,2409]	[370,402]	-8	hSpCas9	negative selection	343438
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-5.593056182767493	[207]	[0]	-9	hSpCas9	negative selection	534459
70925101	70925124	5	+	26472758	Raji	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-5.593056182767493	[207]	[0]	-9	hSpCas9	negative selection	534460
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.6516200983231628	[490]	[178]	6	hSpCas9	negative selection	534463
70941438	70941461	5	-	26472758	Raji	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.6516200983231628	[490]	[178]	6	hSpCas9	negative selection	534464
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.873164101960228	[220]	[13]	-8	hSpCas9	negative selection	534469
70946078	70946101	5	-	26472758	Raji	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.873164101960228	[220]	[13]	-8	hSpCas9	negative selection	534472
70942438	70942461	5	+	26472758	Raji	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.890945711641887	[862]	[53]	-8	hSpCas9	negative selection	534476
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-1.890945711641887	[862]	[53]	-8	hSpCas9	negative selection	534477
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.799507060234919	[359]	[11]	-9	hSpCas9	negative selection	534480
70942808	70942831	5	-	26472758	Raji	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.799507060234919	[359]	[11]	-9	hSpCas9	negative selection	534482
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	0.045099257119256775	[141]	[33]	0	hSpCas9	negative selection	534486
70925166	70925189	5	-	26472758	Raji	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.045099257119256775	[141]	[33]	0	hSpCas9	negative selection	534487
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.9800793058767403	[526]	[30]	-8	hSpCas9	negative selection	534489
70925152	70925175	5	+	26472758	Raji	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.9800793058767403	[526]	[30]	-8	hSpCas9	negative selection	534490
70942454	70942477	5	+	26472758	Raji	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.507765685946433	[820]	[66]	-8	hSpCas9	negative selection	534495
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-1.507765685946433	[820]	[66]	-8	hSpCas9	negative selection	534496
70942849	70942872	5	+	26472758	Raji	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.819765899218719	[250]	[32]	-6	hSpCas9	negative selection	534500
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.819765899218719	[250]	[32]	-6	hSpCas9	negative selection	534501
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.7161513137394389	[1344]	[94]	-8	hSpCas9	negative selection	534503
70925113	70925136	5	+	26472758	Raji	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.7161513137394389	[1344]	[94]	-8	hSpCas9	negative selection	534504
70925101	70925124	5	+	26472758	Raji	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-5.593056182767493	[207]	[0]	-9	hSpCas9	negative selection	534508
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-5.593056182767493	[207]	[0]	-9	hSpCas9	negative selection	534511
70941438	70941461	5	-	26472758	Raji	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.6516200983231628	[490]	[178]	6	hSpCas9	negative selection	534514
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.6516200983231628	[490]	[178]	6	hSpCas9	negative selection	534517
70946078	70946101	5	-	26472758	Raji	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.873164101960228	[220]	[13]	-8	hSpCas9	negative selection	534520
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.873164101960228	[220]	[13]	-8	hSpCas9	negative selection	534521
70942438	70942461	5	+	26472758	Raji	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.890945711641887	[862]	[53]	-8	hSpCas9	negative selection	534523
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-1.890945711641887	[862]	[53]	-8	hSpCas9	negative selection	534524
70942808	70942831	5	-	26472758	Raji	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.799507060234919	[359]	[11]	-9	hSpCas9	negative selection	534529
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-2.799507060234919	[359]	[11]	-9	hSpCas9	negative selection	534531
70925166	70925189	5	-	26472758	Raji	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.045099257119256775	[141]	[33]	0	hSpCas9	negative selection	534534
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	Raji	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	0.045099257119256775	[141]	[33]	0	hSpCas9	negative selection	534537
70925152	70925175	5	+	26472758	Raji	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.9800793058767403	[526]	[30]	-8	hSpCas9	negative selection	534538
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.9800793058767403	[526]	[30]	-8	hSpCas9	negative selection	534541
70942454	70942477	5	+	26472758	Raji	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.507765685946433	[820]	[66]	-8	hSpCas9	negative selection	534543
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-1.507765685946433	[820]	[66]	-8	hSpCas9	negative selection	534544
70942849	70942872	5	+	26472758	Raji	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.819765899218719	[250]	[32]	-6	hSpCas9	negative selection	534549
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	-0.819765899218719	[250]	[32]	-6	hSpCas9	negative selection	534550
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	Raji	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.7161513137394389	[1344]	[94]	-8	hSpCas9	negative selection	534555
70925113	70925136	5	+	26472758	Raji	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.7161513137394389	[1344]	[94]	-8	hSpCas9	negative selection	534556
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.75941313392458	[376]	[93]	-7	hSpCas9	negative selection	725577
70925101	70925124	5	+	26472758	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.75941313392458	[376]	[93]	-7	hSpCas9	negative selection	725578
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.8754508770835879	[677]	[1049]	7	hSpCas9	negative selection	725581
70941438	70941461	5	-	26472758	K562	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.8754508770835879	[677]	[1049]	7	hSpCas9	negative selection	725582
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.282828275198422	[440]	[152]	-6	hSpCas9	negative selection	725587
70946078	70946101	5	-	26472758	K562	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.282828275198422	[440]	[152]	-6	hSpCas9	negative selection	725590
70942438	70942461	5	+	26472758	K562	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-2.526880598528882	[1303]	[190]	-8	hSpCas9	negative selection	725594
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-2.526880598528882	[1303]	[190]	-8	hSpCas9	negative selection	725595
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-3.050764511988387	[480]	[48]	-8	hSpCas9	negative selection	725598
70942808	70942831	5	-	26472758	K562	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-3.050764511988387	[480]	[48]	-8	hSpCas9	negative selection	725600
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-1.4875634589855038	[288]	[86]	-6	hSpCas9	negative selection	725604
70925166	70925189	5	-	26472758	K562	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-1.4875634589855038	[288]	[86]	-6	hSpCas9	negative selection	725605
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.8687918827815442	[635]	[146]	-7	hSpCas9	negative selection	725607
70925152	70925175	5	+	26472758	K562	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.8687918827815442	[635]	[146]	-7	hSpCas9	negative selection	725608
70942454	70942477	5	+	26472758	K562	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-2.394699543101615	[1519]	[243]	-8	hSpCas9	negative selection	725613
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-2.394699543101615	[1519]	[243]	-8	hSpCas9	negative selection	725614
70942849	70942872	5	+	26472758	K562	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	0.11772672275058446	[451]	[413]	0	hSpCas9	negative selection	725618
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	0.11772672275058446	[451]	[413]	0	hSpCas9	negative selection	725619
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.4739910474715154	[2059]	[625]	-6	hSpCas9	negative selection	725621
70925113	70925136	5	+	26472758	K562	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.4739910474715154	[2059]	[625]	-6	hSpCas9	negative selection	725622
70925101	70925124	5	+	26472758	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.75941313392458	[376]	[93]	-7	hSpCas9	negative selection	725626
70268872	70268895	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000275349	-1.75941313392458	[376]	[93]	-7	hSpCas9	negative selection	725629
70941438	70941461	5	-	26472758	K562	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.8754508770835879	[677]	[1049]	7	hSpCas9	negative selection	725632
70285207	70285230	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000275349	0.8754508770835879	[677]	[1049]	7	hSpCas9	negative selection	725635
70946078	70946101	5	-	26472758	K562	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.282828275198422	[440]	[152]	-6	hSpCas9	negative selection	725638
70289847	70289870	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000275349	-1.282828275198422	[440]	[152]	-6	hSpCas9	negative selection	725639
70942438	70942461	5	+	26472758	K562	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-2.526880598528882	[1303]	[190]	-8	hSpCas9	negative selection	725641
70286207	70286230	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000275349	-2.526880598528882	[1303]	[190]	-8	hSpCas9	negative selection	725642
70942808	70942831	5	-	26472758	K562	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-3.050764511988387	[480]	[48]	-8	hSpCas9	negative selection	725647
70286577	70286600	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000275349	-3.050764511988387	[480]	[48]	-8	hSpCas9	negative selection	725649
70925166	70925189	5	-	26472758	K562	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-1.4875634589855038	[288]	[86]	-6	hSpCas9	negative selection	725652
70268937	70268960	CHR_HSCHR5_1_CTG1_1	-	26472758	K562	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000275349	-1.4875634589855038	[288]	[86]	-6	hSpCas9	negative selection	725655
70925152	70925175	5	+	26472758	K562	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.8687918827815442	[635]	[146]	-7	hSpCas9	negative selection	725656
70268923	70268946	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000275349	-1.8687918827815442	[635]	[146]	-7	hSpCas9	negative selection	725659
70942454	70942477	5	+	26472758	K562	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-2.394699543101615	[1519]	[243]	-8	hSpCas9	negative selection	725661
70286223	70286246	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000275349	-2.394699543101615	[1519]	[243]	-8	hSpCas9	negative selection	725662
70942849	70942872	5	+	26472758	K562	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	0.11772672275058446	[451]	[413]	0	hSpCas9	negative selection	725667
70286618	70286641	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000275349	0.11772672275058446	[451]	[413]	0	hSpCas9	negative selection	725668
70268884	70268907	CHR_HSCHR5_1_CTG1_1	+	26472758	K562	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000275349	-1.4739910474715154	[2059]	[625]	-6	hSpCas9	negative selection	725673
70925113	70925136	5	+	26472758	K562	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.4739910474715154	[2059]	[625]	-6	hSpCas9	negative selection	725674
70287138	70287161	CHR_HSCHR5_1_CTG1_1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCGGG	SMN1	ENSG00000275349	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462068
70943369	70943392	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCGGG	SMN1	ENSG00000172062	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462069
70287138	70287161	CHR_HSCHR5_1_CTG1_1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCGGG	SMN1	ENSG00000275349	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557323
70943369	70943392	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCGGG	SMN1	ENSG00000172062	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557324
70925153	70925176	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.8339992681482977	[3,4]	[2,0]	-8	hSpCas9	positive selection	3022255
70942383	70942406	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	0.061882622266480836	[4,4]	[4,4]	1	hSpCas9	positive selection	3022256
70925102	70925125	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.033914749222511115	[2,3]	[3,1]	0	hSpCas9	positive selection	3022257
70925099	70925122	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.7548588824722968	[3,3]	[1,0]	-8	hSpCas9	positive selection	3022258
70925153	70925176	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.39354424813479616	[3,3]	[2,0]	-6	hSpCas9	positive selection	3090113
70942383	70942406	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	-0.21708710398060113	[4,4]	[4,1]	-3	hSpCas9	positive selection	3090114
70925102	70925125	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.38970660954718034	[2,2]	[2,0]	-6	hSpCas9	positive selection	3090115
70925099	70925122	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	0.42267069508877625	[3,3]	[5,1]	7	hSpCas9	positive selection	3090116
70942514	70942537	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTATTAGCTACTTCACAGATTGG	SMN1	ENSG00000172062	-0.7760967900916153	[261,261]	[0,0]	-5	hSpCas9	positive selection	3393932
70942449	70942472	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAGTGTAAACCACAACACAGG	SMN1	ENSG00000172062	0.06750165256581787	[145,145]	[0,0]	0	hSpCas9	positive selection	3393933
70925152	70925175	5	+	26780180	HT29	viability (Avana library 4 designs)	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	3.66492623842329	[]	[]	9	hSpCas9	negative selection	3460835
70942383	70942406	5	-	26780180	HT29	viability (Avana library 4 designs)	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	0.353419838326696	[]	[]	1	hSpCas9	negative selection	3460836
70925101	70925124	5	+	26780180	HT29	viability (Avana library 4 designs)	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	5.61558531088505	[]	[]	9	hSpCas9	negative selection	3460837
70925098	70925121	5	+	26780180	HT29	viability (Avana library 4 designs)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	3.6762244863062	[]	[]	9	hSpCas9	negative selection	3460838
70925101	70925124	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.38741835718362	[]	[]	-3	hSpCas9	negative selection	3561402
70925152	70925175	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-5.85374788326775	[]	[]	-6	hSpCas9	negative selection	3561403
70925098	70925121	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-5.80193231951565	[]	[]	-6	hSpCas9	negative selection	3561404
70942383	70942406	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	-1.58293743292781	[]	[]	-2	hSpCas9	negative selection	3561405
70942379	70942402	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGCCATTTGGTCAGAAGACGG	SMN1	ENSG00000172062	0.428083745416536	[]	[]	0	hSpCas9	negative selection	3561406
70925156	70925179	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCCGCGCCGGAACAGCACGG	SMN1	ENSG00000172062	-14.5486848856944	[]	[]	-9	hSpCas9	negative selection	3561407
70925101	70925124	5	+	26780180	A375	viability (Avana lentiGuide)	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	26.8692747306428	[]	[]	9	hSpCas9	negative selection	3670061
70925152	70925175	5	+	26780180	A375	viability (Avana lentiGuide)	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	21.0878338209796	[]	[]	8	hSpCas9	negative selection	3670062
70925098	70925121	5	+	26780180	A375	viability (Avana lentiGuide)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	17.6146918778212	[]	[]	8	hSpCas9	negative selection	3670063
70942383	70942406	5	-	26780180	A375	viability (Avana lentiGuide)	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	-2.10495788401379	[]	[]	-4	hSpCas9	negative selection	3670064
70942379	70942402	5	+	26780180	A375	viability (Avana lentiGuide)	TCTGCCATTTGGTCAGAAGACGG	SMN1	ENSG00000172062	4.39740441435071	[]	[]	4	hSpCas9	negative selection	3670065
70925156	70925179	5	-	26780180	A375	viability (Avana lentiGuide)	TGTGCCGCGCCGGAACAGCACGG	SMN1	ENSG00000172062	12.8438811574339	[]	[]	7	hSpCas9	negative selection	3670066
70925101	70925124	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.3287209981718078	[6]	[4,4]	-5	hSpCas9	positive selection	3778668
70925152	70925175	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.47554827373947745	[6]	[4,3]	-6	hSpCas9	positive selection	3778669
70925098	70925121	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.4406642114809727	[5]	[4,3]	-6	hSpCas9	positive selection	3778670
70942383	70942406	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	-0.12235029886794235	[5]	[4,5]	-2	hSpCas9	positive selection	3778671
70942379	70942402	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGCCATTTGGTCAGAAGACGG	SMN1	ENSG00000172062	-0.05589962765976625	[6]	[5,6]	-1	hSpCas9	positive selection	3778672
70925156	70925179	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCCGCGCCGGAACAGCACGG	SMN1	ENSG00000172062	-0.82261241662093	[5]	[2,2]	-8	hSpCas9	positive selection	3778673
70925101	70925124	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.7101004343319455	[6]	[2,3]	-7	hSpCas9	positive selection	3887275
70925152	70925175	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.1535252046128237	[7]	[2,1]	-8	hSpCas9	positive selection	3887276
70925098	70925121	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.3947990463225075	[6]	[1,0]	-9	hSpCas9	positive selection	3887277
70942383	70942406	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACCGTCTTCTGACCAAATGG	SMN1	ENSG00000172062	0.2302521755375445	[6]	[6,5]	6	hSpCas9	positive selection	3887278
70942379	70942402	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGCCATTTGGTCAGAAGACGG	SMN1	ENSG00000172062	-0.17306574792264426	[6]	[3,5]	-2	hSpCas9	positive selection	3887279
70925156	70925179	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCCGCGCCGGAACAGCACGG	SMN1	ENSG00000172062	-0.9724392460810886	[5]	[2,0]	-8	hSpCas9	positive selection	3887280
70941475	70941498	5	-	26780180	A375	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.0154422807834356	[]	[]	0	hSpCas9	negative selection	3997382
70941475	70941498	5	-	26780180	A375	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.0154422807834356	[]	[]	0	hSpCas9	negative selection	3997383
70941475	70941498	5	-	26780180	HT29	viability (GeCKOv2 library)	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	-0.228658709553701	[]	[]	-6	hSpCas9	negative selection	4105348
70941475	70941498	5	-	26780180	HT29	viability (GeCKOv2 library)	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	-0.228658709553701	[]	[]	-6	hSpCas9	negative selection	4105349
70941475	70941498	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5132751118692221	[4]	[5,5]	9	hSpCas9	positive selection	4299413
70925166	70925189	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.18518997243832303	[3]	[4,0]	-4	hSpCas9	positive selection	4299414
70925098	70925121	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.209644106308938	[2]	[0,0]	-9	hSpCas9	positive selection	4299415
70941475	70941498	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5132751118692221	[4]	[5,5]	9	hSpCas9	positive selection	4363668
70925101	70925124	5	+	27661255	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-3.724002133700741	[341,449]	[32,15]	-9	dCas9-KRAB	negative selection	5513010
70925482	70925505	5	+	27661255	K562	viability	GTGAAGCAGGGGAACCACTTAGG	SMN1	ENSG00000172062	-2.093947183468117	[1851,1949]	[363,347]	-9	dCas9-KRAB	negative selection	5513013
70925241	70925264	5	-	27661255	K562	viability	GAGGCTGCGGAAGGAGAGTTGGG	SMN1	ENSG00000172062	-2.32441602443508	[1593,1712]	[298,232]	-9	dCas9-KRAB	negative selection	5513015
70925047	70925070	5	+	27661255	K562	viability	GAAGTCGTCACTCTTAAGAAGGG	SMN1	ENSG00000172062	-0.459884145020534	[389,501]	[340,186]	-7	dCas9-KRAB	negative selection	5513016
70925101	70925124	5	+	27661255	K562	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-3.724002133700741	[341,449]	[32,15]	-9	dCas9-KRAB	negative selection	5513018
70925482	70925505	5	+	27661255	K562	viability	GTGAAGCAGGGGAACCACTTAGG	SMN1	ENSG00000172062	-2.093947183468117	[1851,1949]	[363,347]	-9	dCas9-KRAB	negative selection	5513020
70925241	70925264	5	-	27661255	K562	viability	GAGGCTGCGGAAGGAGAGTTGGG	SMN1	ENSG00000172062	-2.32441602443508	[1593,1712]	[298,232]	-9	dCas9-KRAB	negative selection	5513022
70941475	70941498	5	-	27260156	BXPC3	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.24794221935727268	[1715]	[1939,2036,2177,2414]	5	hSpCas9	negative selection	5571873
70925166	70925189	5	-	27260156	BXPC3	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.2635300648124413	[733]	[590,601,744,621]	-5	hSpCas9	negative selection	5571874
70925098	70925121	5	+	27260156	BXPC3	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.0848647018961204	[378]	[187,188,169,199]	-9	hSpCas9	negative selection	5571875
70941475	70941498	5	-	27260156	BXPC3	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.24794221935727268	[1715]	[1939,2036,2177,2414]	5	hSpCas9	negative selection	5636128
70941475	70941498	5	-	27260156	A673	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3256962967546222	[1715]	[2648,2331,2678,2682]	7	hSpCas9	negative selection	5693124
70925166	70925189	5	-	27260156	A673	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.18656578202126262	[733]	[842,764,616,886]	-5	hSpCas9	negative selection	5693125
70925098	70925121	5	+	27260156	A673	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.7093711273811548	[378]	[279,343,235,249]	-9	hSpCas9	negative selection	5693126
70941475	70941498	5	-	27260156	A673	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3256962967546222	[1715]	[2648,2331,2678,2682]	7	hSpCas9	negative selection	5757379
70941475	70941498	5	-	27260156	A375	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5646156070004096	[1715]	[2982,3304,3193,2470]	8	hSpCas9	negative selection	5814375
70925166	70925189	5	-	27260156	A375	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.344694690631991	[733]	[612,797,799,521]	-5	hSpCas9	negative selection	5814376
70925098	70925121	5	+	27260156	A375	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.353185924334454	[378]	[80,134,78,60]	-9	hSpCas9	negative selection	5814377
70941475	70941498	5	-	27260156	A375	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5646156070004096	[1715]	[2982,3304,3193,2470]	8	hSpCas9	negative selection	5878630
70941475	70941498	5	-	27260156	COLO741	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.2830387191978978	[1715]	[2759,2618,2628]	6	hSpCas9	negative selection	5935626
70925166	70925189	5	-	27260156	COLO741	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.076904254935943	[733]	[1109,966,626]	-2	hSpCas9	negative selection	5935627
70925098	70925121	5	+	27260156	COLO741	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.6821139788413619	[378]	[281,261,354]	-8	hSpCas9	negative selection	5935628
70941475	70941498	5	-	27260156	COLO741	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.2830387191978978	[1715]	[2759,2618,2628]	6	hSpCas9	negative selection	5999881
70941475	70941498	5	-	27260156	CAL120	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5056984489545917	[1715]	[3382,2953,2813]	7	hSpCas9	negative selection	6056877
70925166	70925189	5	-	27260156	CAL120	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.429208290630987	[733]	[558,623,830]	-6	hSpCas9	negative selection	6056878
70925098	70925121	5	+	27260156	CAL120	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.6547028084907667	[378]	[115,221,106]	-9	hSpCas9	negative selection	6056879
70941475	70941498	5	-	27260156	CAL120	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5056984489545917	[1715]	[3382,2953,2813]	7	hSpCas9	negative selection	6121132
70941475	70941498	5	-	27260156	CADOES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5909367339388949	[1715]	[2234,2575,2589,2207]	8	hSpCas9	negative selection	6178128
70925166	70925189	5	-	27260156	CADOES1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.23046364913843576	[733]	[707,481,579,555]	-4	hSpCas9	negative selection	6178129
70925098	70925121	5	+	27260156	CADOES1	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.4642148944889875	[378]	[131,118,80,180]	-9	hSpCas9	negative selection	6178130
70941475	70941498	5	-	27260156	CADOES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5909367339388949	[1715]	[2234,2575,2589,2207]	8	hSpCas9	negative selection	6242383
70941475	70941498	5	-	27260156	EWS502	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6015134136061058	[1715]	[2586,2400,3051,3039]	9	hSpCas9	negative selection	6299379
70925166	70925189	5	-	27260156	EWS502	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.4107204018739041	[733]	[558,618,553,607]	-6	hSpCas9	negative selection	6299380
70925098	70925121	5	+	27260156	EWS502	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.31663150772685	[378]	[126,64,51,71]	-9	hSpCas9	negative selection	6299381
70941475	70941498	5	-	27260156	EWS502	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6015134136061058	[1715]	[2586,2400,3051,3039]	9	hSpCas9	negative selection	6363634
70941475	70941498	5	-	27260156	EW8	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4897937698187087	[1715]	[1966,2417,1579,1907]	8	hSpCas9	negative selection	6420630
70925166	70925189	5	-	27260156	EW8	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.28476485396907864	[733]	[685,580,378,346]	-5	hSpCas9	negative selection	6420631
70925098	70925121	5	+	27260156	EW8	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.2243701532912596	[378]	[92,152,168,99]	-9	hSpCas9	negative selection	6420632
70941475	70941498	5	-	27260156	EW8	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4897937698187087	[1715]	[1966,2417,1579,1907]	8	hSpCas9	negative selection	6484885
70941475	70941498	5	-	27260156	CORL105	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.2907437525349119	[1715]	[2193,2326,3171,2241]	5	hSpCas9	negative selection	6541881
70925166	70925189	5	-	27260156	CORL105	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.3440321536829235	[733]	[691,639,771,619]	-6	hSpCas9	negative selection	6541882
70925098	70925121	5	+	27260156	CORL105	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.3187218727213845	[378]	[169,183,233,131]	-9	hSpCas9	negative selection	6541883
70941475	70941498	5	-	27260156	CORL105	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.2907437525349119	[1715]	[2193,2326,3171,2241]	5	hSpCas9	negative selection	6606136
70941475	70941498	5	-	27260156	HS294T	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.43250539496725593	[1715]	[867,783,728,1265]	6	hSpCas9	negative selection	6663132
70925166	70925189	5	-	27260156	HS294T	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.12146577916108847	[733]	[251,384,284,315]	1	hSpCas9	negative selection	6663133
70925098	70925121	5	+	27260156	HS294T	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.4351494538724334	[378]	[64,29,58,63]	-9	hSpCas9	negative selection	6663134
70941475	70941498	5	-	27260156	HS294T	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.43250539496725593	[1715]	[867,783,728,1265]	6	hSpCas9	negative selection	6727387
70941475	70941498	5	-	27260156	HCC44	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3624855153704998	[1715]	[2501,2118,3697,1921]	6	hSpCas9	negative selection	6784383
70925166	70925189	5	-	27260156	HCC44	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.7147599130660236	[733]	[377,454,775,453]	-7	hSpCas9	negative selection	6784384
70925098	70925121	5	+	27260156	HCC44	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.2167350248710833	[378]	[78,122,125,41]	-9	hSpCas9	negative selection	6784385
70941475	70941498	5	-	27260156	HCC44	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3624855153704998	[1715]	[2501,2118,3697,1921]	6	hSpCas9	negative selection	6848638
70941475	70941498	5	-	27260156	G402	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.8277442283844969	[1715]	[4312,4067,3690,2924]	8	hSpCas9	negative selection	6905634
70925166	70925189	5	-	27260156	G402	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.3482307428682287	[733]	[475,857,609,836]	-4	hSpCas9	negative selection	6905635
70925098	70925121	5	+	27260156	G402	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.3232239072591816	[378]	[399,131,143,94]	-9	hSpCas9	negative selection	6905636
70941475	70941498	5	-	27260156	G402	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.8277442283844969	[1715]	[4312,4067,3690,2924]	8	hSpCas9	negative selection	6969889
70941475	70941498	5	-	27260156	L33	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.21098551521735875	[1715]	[2001,944,1248,1651]	4	hSpCas9	negative selection	7026885
70925166	70925189	5	-	27260156	L33	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.40874658001052855	[733]	[1033,452,510,942]	8	hSpCas9	negative selection	7026886
70925098	70925121	5	+	27260156	L33	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.9226927099391024	[378]	[250,86,85,197]	-9	hSpCas9	negative selection	7026887
70941475	70941498	5	-	27260156	L33	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.21098551521735875	[1715]	[2001,944,1248,1651]	4	hSpCas9	negative selection	7091140
70941475	70941498	5	-	27260156	K562	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6813366439348443	[1715]	[2128,2316,2360,2867]	8	hSpCas9	negative selection	7148136
70925166	70925189	5	-	27260156	K562	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.47242914449401757	[733]	[741,503,306,359]	-5	hSpCas9	negative selection	7148137
70925098	70925121	5	+	27260156	K562	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.9993649895937704	[378]	[84,126,122,11]	-9	hSpCas9	negative selection	7148138
70941475	70941498	5	-	27260156	K562	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6813366439348443	[1715]	[2128,2316,2360,2867]	8	hSpCas9	negative selection	7212391
70941475	70941498	5	-	27260156	HT29	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4334401423661116	[1715]	[2902,3019,2768,2605]	8	hSpCas9	negative selection	7269387
70925166	70925189	5	-	27260156	HT29	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.627275628436529	[733]	[512,708,524,566]	-8	hSpCas9	negative selection	7269388
70925098	70925121	5	+	27260156	HT29	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.8136420911331825	[378]	[141,121,169,93]	-9	hSpCas9	negative selection	7269389
70941475	70941498	5	-	27260156	HT29	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4334401423661116	[1715]	[2902,3019,2768,2605]	8	hSpCas9	negative selection	7333642
70941475	70941498	5	-	27260156	MHHES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4525495676469322	[1715]	[3192,2990,2593,1994]	7	hSpCas9	negative selection	7390638
70925166	70925189	5	-	27260156	MHHES1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.24911585191828345	[733]	[712,678,671,700]	-5	hSpCas9	negative selection	7390639
70925098	70925121	5	+	27260156	MHHES1	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.7252469126807392	[378]	[328,241,156,295]	-8	hSpCas9	negative selection	7390640
70941475	70941498	5	-	27260156	MHHES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4525495676469322	[1715]	[3192,2990,2593,1994]	7	hSpCas9	negative selection	7454893
70941475	70941498	5	-	27260156	MEWO	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.20234521056493793	[1715]	[2072,1803,1707]	4	hSpCas9	negative selection	7511889
70925166	70925189	5	-	27260156	MEWO	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.012106642352940344	[733]	[819,695,585]	0	hSpCas9	negative selection	7511890
70925098	70925121	5	+	27260156	MEWO	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.4003094195785395	[378]	[153,87,164]	-9	hSpCas9	negative selection	7511891
70941475	70941498	5	-	27260156	MEWO	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.20234521056493793	[1715]	[2072,1803,1707]	4	hSpCas9	negative selection	7576144
70941475	70941498	5	-	27260156	LNCAPCLONEFGC	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6411294269785512	[1715]	[2048,2342,3030,2374]	8	hSpCas9	negative selection	7633140
70925166	70925189	5	-	27260156	LNCAPCLONEFGC	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.2517809363501177	[733]	[571,532,775,385]	-4	hSpCas9	negative selection	7633141
70925098	70925121	5	+	27260156	LNCAPCLONEFGC	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.0474899743537818	[378]	[101,49,116,69]	-9	hSpCas9	negative selection	7633142
70941475	70941498	5	-	27260156	LNCAPCLONEFGC	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.6411294269785512	[1715]	[2048,2342,3030,2374]	8	hSpCas9	negative selection	7697395
70941475	70941498	5	-	27260156	PANC0327	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.46053043063538524	[1715]	[2157,1878,2245,2139]	6	hSpCas9	negative selection	7754391
70925166	70925189	5	-	27260156	PANC0327	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.490237077284162	[733]	[462,326,431,651]	-6	hSpCas9	negative selection	7754392
70925098	70925121	5	+	27260156	PANC0327	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.90649298214958	[378]	[136,65,30,131]	-9	hSpCas9	negative selection	7754393
70941475	70941498	5	-	27260156	PANC0327	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.46053043063538524	[1715]	[2157,1878,2245,2139]	6	hSpCas9	negative selection	7818646
70941475	70941498	5	-	27260156	NCIH2009	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5591541862201648	[1715]	[3790,3292,3562]	7	hSpCas9	negative selection	7875642
70925166	70925189	5	-	27260156	NCIH2009	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.4970885266345606	[733]	[833,606,760]	-6	hSpCas9	negative selection	7875643
70925098	70925121	5	+	27260156	NCIH2009	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-3.2510227047485407	[378]	[100,40,33]	-9	hSpCas9	negative selection	7875644
70941475	70941498	5	-	27260156	NCIH2009	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5591541862201648	[1715]	[3790,3292,3562]	7	hSpCas9	negative selection	7939897
70941475	70941498	5	-	27260156	NCIH1373	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.9273517815390118	[1715]	[4120,3105,2980,1210]	8	hSpCas9	negative selection	7996893
70925166	70925189	5	-	27260156	NCIH1373	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.3137900517704141	[733]	[625,895,548,140]	-3	hSpCas9	negative selection	7996894
70925098	70925121	5	+	27260156	NCIH1373	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.129118808400594	[378]	[35,44,19,77]	-9	hSpCas9	negative selection	7996895
70941475	70941498	5	-	27260156	NCIH1373	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.9273517815390118	[1715]	[4120,3105,2980,1210]	8	hSpCas9	negative selection	8061148
70941475	70941498	5	-	27260156	PATU8902	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5567653547774036	[1715]	[3987,3479,2496,4436]	6	hSpCas9	negative selection	8118144
70925166	70925189	5	-	27260156	PATU8902	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.39876281179531436	[733]	[664,1103,516,892]	-4	hSpCas9	negative selection	8118145
70925098	70925121	5	+	27260156	PATU8902	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.473755940941677	[378]	[7,242,10,146]	-9	hSpCas9	negative selection	8118146
70941475	70941498	5	-	27260156	PATU8902	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5567653547774036	[1715]	[3987,3479,2496,4436]	6	hSpCas9	negative selection	8182399
70941475	70941498	5	-	27260156	PANC1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5220532817797887	[1715]	[1878,2609,1907,2134]	8	hSpCas9	negative selection	8239395
70925166	70925189	5	-	27260156	PANC1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.2201026556307054	[733]	[488,643,491,550]	-4	hSpCas9	negative selection	8239396
70925098	70925121	5	+	27260156	PANC1	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.644459819783258	[378]	[57,51,43,52]	-9	hSpCas9	negative selection	8239397
70941475	70941498	5	-	27260156	PANC1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5220532817797887	[1715]	[1878,2609,1907,2134]	8	hSpCas9	negative selection	8303650
70941475	70941498	5	-	27260156	PANC0813	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.49586327045683176	[1715]	[3358,2663,2777,2623]	7	hSpCas9	negative selection	8360646
70925166	70925189	5	-	27260156	PANC0813	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.5282927053314168	[733]	[531,744,565,543]	-7	hSpCas9	negative selection	8360647
70925098	70925121	5	+	27260156	PANC0813	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.8896712325332845	[378]	[134,101,76,164]	-9	hSpCas9	negative selection	8360648
70941475	70941498	5	-	27260156	PANC0813	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.49586327045683176	[1715]	[3358,2663,2777,2623]	7	hSpCas9	negative selection	8424901
70941475	70941498	5	-	27260156	RDES	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5746025550785407	[1715]	[2149,3150,3218,3376]	8	hSpCas9	negative selection	8481897
70925166	70925189	5	-	27260156	RDES	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.23973497559807022	[733]	[584,603,712,1021]	-4	hSpCas9	negative selection	8481898
70925098	70925121	5	+	27260156	RDES	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.8738523736382868	[378]	[68,58,177,197]	-9	hSpCas9	negative selection	8481899
70941475	70941498	5	-	27260156	RDES	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5746025550785407	[1715]	[2149,3150,3218,3376]	8	hSpCas9	negative selection	8546152
70941475	70941498	5	-	27260156	PC3	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.38202841495215156	[1715]	[1647,2031,3848,2023]	7	hSpCas9	negative selection	8603148
70925166	70925189	5	-	27260156	PC3	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.0919776820799858	[733]	[421,671,1068,786]	-2	hSpCas9	negative selection	8603149
70925098	70925121	5	+	27260156	PC3	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.2915874288113005	[378]	[87,213,161,167]	-9	hSpCas9	negative selection	8603150
70941475	70941498	5	-	27260156	PC3	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.38202841495215156	[1715]	[1647,2031,3848,2023]	7	hSpCas9	negative selection	8667403
70941475	70941498	5	-	27260156	PATU8988T	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4494461589761307	[1715]	[2277,2475,2219,2088]	7	hSpCas9	negative selection	8724399
70925166	70925189	5	-	27260156	PATU8988T	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.319130296584629	[733]	[493,522,663,588]	-5	hSpCas9	negative selection	8724400
70925098	70925121	5	+	27260156	PATU8988T	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.0530610596677024	[378]	[72,519,107,25]	-9	hSpCas9	negative selection	8724401
70941475	70941498	5	-	27260156	PATU8988T	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4494461589761307	[1715]	[2277,2475,2219,2088]	7	hSpCas9	negative selection	8788654
70941475	70941498	5	-	27260156	T47D	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4043745929737501	[1715]	[2406,2616,2480,3095]	8	hSpCas9	negative selection	8845650
70925166	70925189	5	-	27260156	T47D	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.3091046851964987	[733]	[692,685,627,756]	-6	hSpCas9	negative selection	8845651
70925098	70925121	5	+	27260156	T47D	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.8618363498516959	[378]	[91,130,111,150]	-9	hSpCas9	negative selection	8845652
70941475	70941498	5	-	27260156	T47D	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.4043745929737501	[1715]	[2406,2616,2480,3095]	8	hSpCas9	negative selection	8909905
70941475	70941498	5	-	27260156	SU8686	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5599796633425325	[1715]	[2252,1967,2678,3355]	8	hSpCas9	negative selection	8966901
70925166	70925189	5	-	27260156	SU8686	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.47452783983315294	[733]	[373,506,564,692]	-6	hSpCas9	negative selection	8966902
70925098	70925121	5	+	27260156	SU8686	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-2.4093244559609266	[378]	[50,36,111,93]	-9	hSpCas9	negative selection	8966903
70941475	70941498	5	-	27260156	SU8686	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.5599796633425325	[1715]	[2252,1967,2678,3355]	8	hSpCas9	negative selection	9031156
70941475	70941498	5	-	27260156	SKES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3559832926212454	[1715]	[2618,2431,1850,1958]	7	hSpCas9	negative selection	9088152
70925166	70925189	5	-	27260156	SKES1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.17044090532997458	[733]	[576,769,495,746]	-4	hSpCas9	negative selection	9088153
70925098	70925121	5	+	27260156	SKES1	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.4700087420327628	[378]	[191,150,98,114]	-9	hSpCas9	negative selection	9088154
70941475	70941498	5	-	27260156	SKES1	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.3559832926212454	[1715]	[2618,2431,1850,1958]	7	hSpCas9	negative selection	9152407
70941475	70941498	5	-	27260156	TOV112D	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.18396327765605514	[1715]	[1984,2033,2249,1570]	3	hSpCas9	negative selection	9209403
70925166	70925189	5	-	27260156	TOV112D	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.045418708366288585	[733]	[624,932,726,612]	-1	hSpCas9	negative selection	9209404
70925098	70925121	5	+	27260156	TOV112D	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-1.0676498913198547	[378]	[127,234,228,141]	-9	hSpCas9	negative selection	9209405
70941475	70941498	5	-	27260156	TOV112D	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.18396327765605514	[1715]	[1984,2033,2249,1570]	3	hSpCas9	negative selection	9273658
70941475	70941498	5	-	27260156	TC71	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.29219179301733944	[1715]	[1884,2320,2408,2406]	7	hSpCas9	negative selection	9330654
70925166	70925189	5	-	27260156	TC71	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.1170831132897826	[733]	[847,713,502,848]	-3	hSpCas9	negative selection	9330655
70925098	70925121	5	+	27260156	TC71	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.6550837870560535	[378]	[269,214,254,293]	-9	hSpCas9	negative selection	9330656
70941475	70941498	5	-	27260156	TC71	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.29219179301733944	[1715]	[1884,2320,2408,2406]	7	hSpCas9	negative selection	9394909
70941475	70941498	5	-	27260156	TC32	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.47669761951445744	[1715]	[2067,1711,2838,2567]	7	hSpCas9	negative selection	9451905
70925166	70925189	5	-	27260156	TC32	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.15464690920658836	[733]	[602,560,710,602]	-3	hSpCas9	negative selection	9451906
70925098	70925121	5	+	27260156	TC32	viability	TTTGCTATGGCGATGAGCAGCGG	SMN1	ENSG00000172062	-0.7811769324320289	[378]	[158,151,244,299]	-9	hSpCas9	negative selection	9451907
70941475	70941498	5	-	27260156	TC32	viability	AAGCTGCAGTATTCTTCTTTTGG	SMN1	ENSG00000172062	0.47669761951445744	[1715]	[2067,1711,2838,2567]	7	hSpCas9	negative selection	9516160
70925101	70925124	5	+	28162770	P31FUJ	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.8957672171368078	[132]	[41]	-8	hSpCas9	negative selection	10239347
70941438	70941461	5	-	28162770	P31FUJ	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.9363005142807439	[389]	[876]	9	hSpCas9	negative selection	10239348
70946078	70946101	5	-	28162770	P31FUJ	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.3355617788395794	[159]	[148]	-3	hSpCas9	negative selection	10239349
70942438	70942461	5	+	28162770	P31FUJ	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.3255963000862379	[609]	[285]	-7	hSpCas9	negative selection	10239350
70942808	70942831	5	-	28162770	P31FUJ	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.1117103874970167	[216]	[58]	-8	hSpCas9	negative selection	10239351
70925166	70925189	5	-	28162770	P31FUJ	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.6517205781656854	[181]	[335]	7	hSpCas9	negative selection	10239352
70925152	70925175	5	+	28162770	P31FUJ	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.4851893660486637	[566]	[237]	-7	hSpCas9	negative selection	10239353
70942454	70942477	5	+	28162770	P31FUJ	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.4082607715400983	[750]	[664]	-4	hSpCas9	negative selection	10239354
70942849	70942872	5	+	28162770	P31FUJ	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.21769531202417025	[379]	[383]	-2	hSpCas9	negative selection	10239355
70925113	70925136	5	+	28162770	P31FUJ	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.2484554687258642	[1111]	[549]	-7	hSpCas9	negative selection	10239356
70925101	70925124	5	+	28162770	TF1	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10408713
70941438	70941461	5	-	28162770	TF1	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	NaN	[NaN]	[663]	1	hSpCas9	negative selection	10408714
70946078	70946101	5	-	28162770	TF1	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10408715
70942438	70942461	5	+	28162770	TF1	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10408716
70942808	70942831	5	-	28162770	TF1	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10408717
70925166	70925189	5	-	28162770	TF1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	NaN	[NaN]	[83]	1	hSpCas9	negative selection	10408718
70925152	70925175	5	+	28162770	TF1	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10408719
70942454	70942477	5	+	28162770	TF1	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10408720
70942849	70942872	5	+	28162770	TF1	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10408721
70925113	70925136	5	+	28162770	TF1	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	NaN	[NaN]	[364]	1	hSpCas9	negative selection	10408722
70925101	70925124	5	+	28162770	SKM1	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.9182170132813088	[30]	[28]	-6	hSpCas9	negative selection	10578079
70941438	70941461	5	-	28162770	SKM1	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.5274071332874638	[103]	[264]	5	hSpCas9	negative selection	10578080
70946078	70946101	5	-	28162770	SKM1	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.1439297929093679	[54]	[87]	-1	hSpCas9	negative selection	10578081
70942438	70942461	5	+	28162770	SKM1	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.0539484260717022	[201]	[171]	-6	hSpCas9	negative selection	10578082
70942808	70942831	5	-	28162770	SKM1	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.1074039168842535	[77]	[31]	-8	hSpCas9	negative selection	10578083
70925166	70925189	5	-	28162770	SKM1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.42063913564023814	[52]	[69]	-3	hSpCas9	negative selection	10578084
70925152	70925175	5	+	28162770	SKM1	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.8475367901291431	[113]	[111]	-6	hSpCas9	negative selection	10578085
70942454	70942477	5	+	28162770	SKM1	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.1182431492457185	[166]	[135]	-7	hSpCas9	negative selection	10578086
70942849	70942872	5	+	28162770	SKM1	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.77196101552241	[84]	[87]	-5	hSpCas9	negative selection	10578087
70925113	70925136	5	+	28162770	SKM1	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-0.8394187510994149	[249]	[246]	-6	hSpCas9	negative selection	10578088
70925101	70925124	5	+	28162770	SKM1	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-0.9182170132813088	[30]	[28]	-6	hSpCas9	negative selection	10747445
70941438	70941461	5	-	28162770	SKM1	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.5274071332874638	[103]	[264]	5	hSpCas9	negative selection	10747446
70946078	70946101	5	-	28162770	SKM1	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.1439297929093679	[54]	[87]	-1	hSpCas9	negative selection	10747447
70942438	70942461	5	+	28162770	SKM1	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.0539484260717022	[201]	[171]	-6	hSpCas9	negative selection	10747448
70942808	70942831	5	-	28162770	SKM1	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.1074039168842535	[77]	[31]	-8	hSpCas9	negative selection	10747449
70925166	70925189	5	-	28162770	SKM1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.42063913564023814	[52]	[69]	-3	hSpCas9	negative selection	10747450
70925152	70925175	5	+	28162770	SKM1	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.8475367901291431	[113]	[111]	-6	hSpCas9	negative selection	10747451
70942454	70942477	5	+	28162770	SKM1	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.1182431492457185	[166]	[135]	-7	hSpCas9	negative selection	10747452
70942849	70942872	5	+	28162770	SKM1	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.77196101552241	[84]	[87]	-5	hSpCas9	negative selection	10747453
70925113	70925136	5	+	28162770	SKM1	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-0.8394187510994149	[249]	[246]	-6	hSpCas9	negative selection	10747454
70925101	70925124	5	+	28162770	PL21	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-3.14563522235241	[121]	[5]	-9	hSpCas9	negative selection	10916811
70941438	70941461	5	-	28162770	PL21	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.11211486669209603	[320]	[150]	1	hSpCas9	negative selection	10916812
70946078	70946101	5	-	28162770	PL21	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	0.33865947857074796	[128]	[70]	3	hSpCas9	negative selection	10916813
70942438	70942461	5	+	28162770	PL21	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-0.5347635132199935	[698]	[209]	-4	hSpCas9	negative selection	10916814
70942808	70942831	5	-	28162770	PL21	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-1.9373639092606145	[307]	[34]	-8	hSpCas9	negative selection	10916815
70925166	70925189	5	-	28162770	PL21	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.90811300531582	[190]	[155]	7	hSpCas9	negative selection	10916816
70925152	70925175	5	+	28162770	PL21	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-2.2852872126809216	[391]	[34]	-8	hSpCas9	negative selection	10916817
70942454	70942477	5	+	28162770	PL21	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.3596223321066936	[453]	[153]	-3	hSpCas9	negative selection	10916818
70942849	70942872	5	+	28162770	PL21	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-1.1783720087644098	[233]	[44]	-7	hSpCas9	negative selection	10916819
70925113	70925136	5	+	28162770	PL21	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-0.5681684034364702	[728]	[213]	-4	hSpCas9	negative selection	10916820
70925101	70925124	5	+	28162770	P31FUJ	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.8957672171368078	[132]	[41]	-8	hSpCas9	negative selection	11086177
70941438	70941461	5	-	28162770	P31FUJ	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.9363005142807439	[389]	[876]	9	hSpCas9	negative selection	11086178
70946078	70946101	5	-	28162770	P31FUJ	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.3355617788395794	[159]	[148]	-3	hSpCas9	negative selection	11086179
70942438	70942461	5	+	28162770	P31FUJ	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.3255963000862379	[609]	[285]	-7	hSpCas9	negative selection	11086180
70942808	70942831	5	-	28162770	P31FUJ	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.1117103874970167	[216]	[58]	-8	hSpCas9	negative selection	11086181
70925166	70925189	5	-	28162770	P31FUJ	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.6517205781656854	[181]	[335]	7	hSpCas9	negative selection	11086182
70925152	70925175	5	+	28162770	P31FUJ	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.4851893660486637	[566]	[237]	-7	hSpCas9	negative selection	11086183
70942454	70942477	5	+	28162770	P31FUJ	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.4082607715400983	[750]	[664]	-4	hSpCas9	negative selection	11086184
70942849	70942872	5	+	28162770	P31FUJ	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.21769531202417025	[379]	[383]	-2	hSpCas9	negative selection	11086185
70925113	70925136	5	+	28162770	P31FUJ	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.2484554687258642	[1111]	[549]	-7	hSpCas9	negative selection	11086186
70925101	70925124	5	+	28162770	OCIAML5	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-1.7227835539190304	[63]	[34]	-7	hSpCas9	negative selection	11255543
70941438	70941461	5	-	28162770	OCIAML5	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.8151805603570497	[300]	[955]	7	hSpCas9	negative selection	11255544
70946078	70946101	5	-	28162770	OCIAML5	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.29063958460363	[102]	[75]	-6	hSpCas9	negative selection	11255545
70942438	70942461	5	+	28162770	OCIAML5	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.689060983361475	[417]	[233]	-7	hSpCas9	negative selection	11255546
70942808	70942831	5	-	28162770	OCIAML5	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.1151009766977906	[143]	[59]	-8	hSpCas9	negative selection	11255547
70925166	70925189	5	-	28162770	OCIAML5	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.15498818666995345	[101]	[204]	1	hSpCas9	negative selection	11255548
70925152	70925175	5	+	28162770	OCIAML5	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.48433478636351	[309]	[199]	-7	hSpCas9	negative selection	11255549
70942454	70942477	5	+	28162770	OCIAML5	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.7439639635546212	[346]	[373]	-5	hSpCas9	negative selection	11255550
70942849	70942872	5	+	28162770	OCIAML5	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.8437513026519934	[172]	[173]	-5	hSpCas9	negative selection	11255551
70925113	70925136	5	+	28162770	OCIAML5	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.4698937054907795	[665]	[433]	-7	hSpCas9	negative selection	11255552
70925101	70925124	5	+	28162770	EOL1	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-4.113587357316237	[229]	[6]	-9	hSpCas9	negative selection	11424909
70941438	70941461	5	-	28162770	EOL1	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.8332326048245887	[374]	[351]	7	hSpCas9	negative selection	11424910
70946078	70946101	5	-	28162770	EOL1	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	0.004601023136569654	[332]	[175]	0	hSpCas9	negative selection	11424911
70942438	70942461	5	+	28162770	EOL1	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.4968361775066945	[1290]	[240]	-7	hSpCas9	negative selection	11424912
70942808	70942831	5	-	28162770	EOL1	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-1.7104554116502173	[527]	[84]	-8	hSpCas9	negative selection	11424913
70925166	70925189	5	-	28162770	EOL1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.3988244742240543	[333]	[231]	3	hSpCas9	negative selection	11424914
70925152	70925175	5	+	28162770	EOL1	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-0.6489190903127924	[624]	[209]	-5	hSpCas9	negative selection	11424915
70942454	70942477	5	+	28162770	EOL1	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.8736587682728842	[785]	[225]	-6	hSpCas9	negative selection	11424916
70942849	70942872	5	+	28162770	EOL1	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.6988888769652575	[341]	[110]	-5	hSpCas9	negative selection	11424917
70925113	70925136	5	+	28162770	EOL1	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-0.9569933950211085	[1226]	[332]	-6	hSpCas9	negative selection	11424918
70925101	70925124	5	+	28162770	MOLM13	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.965070025731528	[161]	[14]	-8	hSpCas9	negative selection	11594275
70941438	70941461	5	-	28162770	MOLM13	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	1.1919736844140525	[404]	[668]	8	hSpCas9	negative selection	11594276
70946078	70946101	5	-	28162770	MOLM13	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.9814180198190112	[212]	[38]	-7	hSpCas9	negative selection	11594277
70942438	70942461	5	+	28162770	MOLM13	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.9149352345802337	[870]	[166]	-7	hSpCas9	negative selection	11594278
70942808	70942831	5	-	28162770	MOLM13	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.7424704842969723	[397]	[42]	-8	hSpCas9	negative selection	11594279
70925166	70925189	5	-	28162770	MOLM13	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.5996739022680557	[305]	[145]	-3	hSpCas9	negative selection	11594280
70925152	70925175	5	+	28162770	MOLM13	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.6539413316966884	[530]	[121]	-7	hSpCas9	negative selection	11594281
70942454	70942477	5	+	28162770	MOLM13	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.8820934440540223	[700]	[274]	-5	hSpCas9	negative selection	11594282
70942849	70942872	5	+	28162770	MOLM13	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-1.292030197715273	[358]	[105]	-6	hSpCas9	negative selection	11594283
70925113	70925136	5	+	28162770	MOLM13	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.5692739082748675	[1218]	[296]	-6	hSpCas9	negative selection	11594284
70925101	70925124	5	+	28162770	HEL	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-4.138620881524303	[164]	[5]	-9	hSpCas9	negative selection	11763641
70941438	70941461	5	-	28162770	HEL	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.8353839099427528	[321]	[367]	7	hSpCas9	negative selection	11763642
70946078	70946101	5	-	28162770	HEL	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-3.2861780699381606	[197]	[12]	-9	hSpCas9	negative selection	11763643
70942438	70942461	5	+	28162770	HEL	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.699786167494119	[775]	[152]	-7	hSpCas9	negative selection	11763644
70942808	70942831	5	-	28162770	HEL	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-4.440861369617584	[372]	[10]	-9	hSpCas9	negative selection	11763645
70925166	70925189	5	-	28162770	HEL	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.7893886909512001	[242]	[268]	6	hSpCas9	negative selection	11763646
70925152	70925175	5	+	28162770	HEL	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-2.4835969008942724	[488]	[55]	-8	hSpCas9	negative selection	11763647
70942454	70942477	5	+	28162770	HEL	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-1.7783988668149049	[631]	[117]	-7	hSpCas9	negative selection	11763648
70942849	70942872	5	+	28162770	HEL	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-2.4879648596442365	[253]	[28]	-8	hSpCas9	negative selection	11763649
70925113	70925136	5	+	28162770	HEL	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.9130236922722246	[1075]	[182]	-7	hSpCas9	negative selection	11763650
70925101	70925124	5	+	28162770	MV411	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.2719366083108046	[85]	[14]	-8	hSpCas9	negative selection	11933007
70941438	70941461	5	-	28162770	MV411	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.9440454073328407	[289]	[469]	8	hSpCas9	negative selection	11933008
70946078	70946101	5	-	28162770	MV411	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.24507870117378594	[203]	[144]	-2	hSpCas9	negative selection	11933009
70942438	70942461	5	+	28162770	MV411	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-0.7315008336893949	[543]	[275]	-5	hSpCas9	negative selection	11933010
70942808	70942831	5	-	28162770	MV411	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.3761462439656884	[264]	[42]	-8	hSpCas9	negative selection	11933011
70925166	70925189	5	-	28162770	MV411	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.7670056335329261	[172]	[247]	7	hSpCas9	negative selection	11933012
70925152	70925175	5	+	28162770	MV411	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-2.6499927155766767	[379]	[50]	-9	hSpCas9	negative selection	11933013
70942454	70942477	5	+	28162770	MV411	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.4345014312330886	[522]	[325]	-3	hSpCas9	negative selection	11933014
70942849	70942872	5	+	28162770	MV411	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.49578703385511297	[230]	[137]	-4	hSpCas9	negative selection	11933015
70925113	70925136	5	+	28162770	MV411	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.989866579957601	[777]	[164]	-8	hSpCas9	negative selection	11933016
70925101	70925124	5	+	28162770	MONOMAC1	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.0595333233096187	[79]	[21]	-9	hSpCas9	negative selection	12102373
70941438	70941461	5	-	28162770	MONOMAC1	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	-0.560727466338177	[183]	[142]	-5	hSpCas9	negative selection	12102374
70946078	70946101	5	-	28162770	MONOMAC1	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.2164021719264848	[74]	[73]	-2	hSpCas9	negative selection	12102375
70942438	70942461	5	+	28162770	MONOMAC1	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-2.0060136861411477	[444]	[126]	-8	hSpCas9	negative selection	12102376
70942808	70942831	5	-	28162770	MONOMAC1	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.9499439850947815	[181]	[26]	-9	hSpCas9	negative selection	12102377
70925166	70925189	5	-	28162770	MONOMAC1	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.2574094650390354	[121]	[116]	-2	hSpCas9	negative selection	12102378
70925152	70925175	5	+	28162770	MONOMAC1	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.2756466817559204	[263]	[124]	-7	hSpCas9	negative selection	12102379
70942454	70942477	5	+	28162770	MONOMAC1	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.8438578181877516	[273]	[174]	-6	hSpCas9	negative selection	12102380
70942849	70942872	5	+	28162770	MONOMAC1	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.36092293202052567	[148]	[132]	-3	hSpCas9	negative selection	12102381
70925113	70925136	5	+	28162770	MONOMAC1	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.3920528294646966	[608]	[265]	-8	hSpCas9	negative selection	12102382
70925101	70925124	5	+	28162770	OCIAML2	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.634128557525041	[27]	[24]	-9	hSpCas9	negative selection	12271739
70941438	70941461	5	-	28162770	OCIAML2	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.6523516745898756	[58]	[513]	6	hSpCas9	negative selection	12271740
70946078	70946101	5	-	28162770	OCIAML2	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-0.040641984497345796	[17]	[96]	0	hSpCas9	negative selection	12271741
70942438	70942461	5	+	28162770	OCIAML2	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-1.4642603003664338	[112]	[226]	-7	hSpCas9	negative selection	12271742
70942808	70942831	5	-	28162770	OCIAML2	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-2.6281711022286416	[57]	[51]	-8	hSpCas9	negative selection	12271743
70925166	70925189	5	-	28162770	OCIAML2	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	0.09968589951459353	[32]	[195]	0	hSpCas9	negative selection	12271744
70925152	70925175	5	+	28162770	OCIAML2	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.6298284200914153	[66]	[119]	-7	hSpCas9	negative selection	12271745
70942454	70942477	5	+	28162770	OCIAML2	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.22346949875677136	[98]	[469]	-2	hSpCas9	negative selection	12271746
70942849	70942872	5	+	28162770	OCIAML2	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-1.2335906279413118	[41]	[98]	-7	hSpCas9	negative selection	12271747
70925113	70925136	5	+	28162770	OCIAML2	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.7668712764658738	[166]	[271]	-8	hSpCas9	negative selection	12271748
70925101	70925124	5	+	28162770	OCIAML3	viability	GCTATGGCGATGAGCAGCGGCGG	SMN1	ENSG00000172062	-2.4538299822759027	[48]	[26]	-9	hSpCas9	negative selection	12441105
70941438	70941461	5	-	28162770	OCIAML3	viability	AGCAGGTTTTCTTTTAGGTGTGG	SMN1	ENSG00000172062	0.017427071758184032	[89]	[274]	0	hSpCas9	negative selection	12441106
70946078	70946101	5	-	28162770	OCIAML3	viability	GAATCTGGACATATGGGAGGTGG	SMN1	ENSG00000172062	-1.206984517214916	[51]	[67]	-7	hSpCas9	negative selection	12441107
70942438	70942461	5	+	28162770	OCIAML3	viability	TAAGAGAGAAACCTGTGTTGTGG	SMN1	ENSG00000172062	-0.5973982295249374	[212]	[424]	-4	hSpCas9	negative selection	12441108
70942808	70942831	5	-	28162770	OCIAML3	viability	GGAGGGAGAAAAGAGTTCCATGG	SMN1	ENSG00000172062	-1.2720795454368008	[75]	[94]	-7	hSpCas9	negative selection	12441109
70925166	70925189	5	-	28162770	OCIAML3	viability	TCACCTGGCCTGTGCCGCGCCGG	SMN1	ENSG00000172062	-0.26010690377072493	[47]	[120]	-2	hSpCas9	negative selection	12441110
70925152	70925175	5	+	28162770	OCIAML3	viability	GATTCCGTGCTGTTCCGGCGCGG	SMN1	ENSG00000172062	-1.7639326417664756	[125]	[111]	-8	hSpCas9	negative selection	12441111
70942454	70942477	5	+	28162770	OCIAML3	viability	GTTGTGGTTTACACTGGATATGG	SMN1	ENSG00000172062	-0.10451114884487422	[176]	[496]	-1	hSpCas9	negative selection	12441112
70942849	70942872	5	+	28162770	OCIAML3	viability	GCCAAGACTGGGACCAGGAAAGG	SMN1	ENSG00000172062	-0.6216639832270284	[78]	[154]	-5	hSpCas9	negative selection	12441113
70925113	70925136	5	+	28162770	OCIAML3	viability	AGCAGCGGCGGCAGTGGTGGCGG	SMN1	ENSG00000172062	-1.4879660029138386	[235]	[253]	-7	hSpCas9	negative selection	12441114