Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6609
• Symbol: SMPD1
• Description: sphingomyelin phosphodiesterase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/SMPD1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
6391387	6391410	11	+	26472758	Jiyoye	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	1.4515695008643266	[63]	[131]	8	hSpCas9	negative selection	152369
6392122	6392145	11	-	26472758	Jiyoye	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	-0.4715183222719932	[56]	[30]	-3	hSpCas9	negative selection	152370
6391658	6391681	11	-	26472758	Jiyoye	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	1.618679486699585	[18]	[43]	8	hSpCas9	negative selection	152371
6391741	6391764	11	-	26472758	Jiyoye	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	1.5998204594482692	[13]	[31]	8	hSpCas9	negative selection	152372
6391871	6391894	11	-	26472758	Jiyoye	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.48117596294965015	[18]	[19]	3	hSpCas9	negative selection	152373
6391932	6391955	11	+	26472758	Jiyoye	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.7761753101561029	[198]	[256]	5	hSpCas9	negative selection	152374
6392060	6392083	11	-	26472758	Jiyoye	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	0.5871540476121087	[142]	[161]	4	hSpCas9	negative selection	152375
6393246	6393269	11	-	26472758	Jiyoye	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.07345045940054717	[59]	[42]	0	hSpCas9	negative selection	152376
6390688	6390711	11	-	26472758	Jiyoye	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	1.0021219707996516	[95]	[144]	6	hSpCas9	negative selection	152377
6391828	6391851	11	-	26472758	Jiyoye	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	0.9985356534251801	[74]	[112]	6	hSpCas9	negative selection	152378
6391387	6391410	11	+	26472758	KBM7	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.4311643858181727	[728,599]	[274,547]	4	hSpCas9	negative selection	343487
6392122	6392145	11	-	26472758	KBM7	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.3132471417868665	[293,215]	[130,161]	3	hSpCas9	negative selection	343488
6391658	6391681	11	-	26472758	KBM7	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.33589935115808145	[164,170]	[83,114]	3	hSpCas9	negative selection	343489
6391741	6391764	11	-	26472758	KBM7	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.5584858321196173	[83,99]	[33,25]	-5	hSpCas9	negative selection	343490
6391871	6391894	11	-	26472758	KBM7	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	1.0862680718573743	[82,157]	[233,26]	9	hSpCas9	negative selection	343491
6391932	6391955	11	+	26472758	KBM7	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.4483787525347247	[1035,1054]	[803,558]	5	hSpCas9	negative selection	343492
6392060	6392083	11	-	26472758	KBM7	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	0.06140659470557708	[1073,1059]	[436,604]	0	hSpCas9	negative selection	343493
6393246	6393269	11	-	26472758	KBM7	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.9547732241741346	[410,302]	[119,54]	-6	hSpCas9	negative selection	343494
6390688	6390711	11	-	26472758	KBM7	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.2474114082574505	[387,446]	[285,190]	2	hSpCas9	negative selection	343495
6391828	6391851	11	-	26472758	KBM7	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	0.5337709001717903	[465,444]	[313,307]	6	hSpCas9	negative selection	343496
6391387	6391410	11	+	26472758	Raji	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.3611694732322459	[237]	[42]	-3	hSpCas9	negative selection	534605
6392122	6392145	11	-	26472758	Raji	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.5678640054136105	[124]	[42]	5	hSpCas9	negative selection	534606
6391658	6391681	11	-	26472758	Raji	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	1.3207871734827927	[68]	[39]	9	hSpCas9	negative selection	534607
6391741	6391764	11	-	26472758	Raji	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	0.48847370272910573	[42]	[13]	4	hSpCas9	negative selection	534608
6391871	6391894	11	-	26472758	Raji	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.7685816219218411	[42]	[16]	7	hSpCas9	negative selection	534609
6391932	6391955	11	+	26472758	Raji	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.1893991098814961	[358]	[94]	1	hSpCas9	negative selection	534610
6392060	6392083	11	-	26472758	Raji	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.40892260468061437	[594]	[103]	-3	hSpCas9	negative selection	534611
6393246	6393269	11	-	26472758	Raji	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.1252772214166754	[187]	[39]	-1	hSpCas9	negative selection	534612
6390688	6390711	11	-	26472758	Raji	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.9393456434755525	[190]	[84]	8	hSpCas9	negative selection	534613
6391828	6391851	11	-	26472758	Raji	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.8885120662936637	[350]	[43]	-6	hSpCas9	negative selection	534614
6391387	6391410	11	+	26472758	K562	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.4622909519655125	[410]	[477]	3	hSpCas9	negative selection	725723
6392122	6392145	11	-	26472758	K562	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.5003637087139212	[169]	[202]	4	hSpCas9	negative selection	725724
6391658	6391681	11	-	26472758	K562	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.5944761957376066	[192]	[245]	5	hSpCas9	negative selection	725725
6391741	6391764	11	-	26472758	K562	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.15997152741288856	[44]	[33]	-1	hSpCas9	negative selection	725726
6391871	6391894	11	-	26472758	K562	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.8110763849252567	[105]	[50]	-5	hSpCas9	negative selection	725727
6391932	6391955	11	+	26472758	K562	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.7147386624464803	[671]	[930]	6	hSpCas9	negative selection	725728
6392060	6392083	11	-	26472758	K562	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.36694677215169813	[1157]	[757]	-2	hSpCas9	negative selection	725729
6393246	6393269	11	-	26472758	K562	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.2871943484617758	[291]	[100]	-6	hSpCas9	negative selection	725730
6390688	6390711	11	-	26472758	K562	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.24029229941920813	[402]	[287]	-2	hSpCas9	negative selection	725731
6391828	6391851	11	-	26472758	K562	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.2731158455344186	[417]	[291]	-2	hSpCas9	negative selection	725732
6390678	6390701	11	-	26627737	DLD1	viability	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.760471607368935	[103]	[20,1,5]	-8	hSpCas9	negative selection	779908
6390831	6390854	11	-	26627737	DLD1	viability	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.3269548774945032	[419]	[362,325,302]	9	hSpCas9	negative selection	779909
6391737	6391760	11	+	26627737	DLD1	viability	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	-0.5315398386672532	[230]	[2,28,107]	-5	hSpCas9	negative selection	779916
6393310	6393333	11	+	26627737	DLD1	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.13267171785135878	[252]	[165,105,1]	1	hSpCas9	negative selection	779917
6394009	6394032	11	-	26627737	DLD1	viability	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.11508224907484588	[762]	[277,252,142]	-1	hSpCas9	negative selection	779918
6394369	6394392	11	-	26627737	DLD1	viability	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.4405466114672567	[252]	[147,40,126]	4	hSpCas9	negative selection	779919
6390678	6390701	11	-	26627737	GBM cells	viability after 5 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	0.4359418985431398	[50]	[47,25]	6	hSpCas9	negative selection	862223
6390831	6390854	11	-	26627737	GBM cells	viability after 5 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.5990682780765965	[388]	[331,299]	8	hSpCas9	negative selection	862224
6391737	6391760	11	+	26627737	GBM cells	viability after 5 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.306571843798932	[48]	[35,28]	5	hSpCas9	negative selection	862231
6393310	6393333	11	+	26627737	GBM cells	viability after 5 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.0910324604503917	[142]	[59,83]	-1	hSpCas9	negative selection	862232
6394009	6394032	11	-	26627737	GBM cells	viability after 5 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-1.117266052169749	[268]	[59,72]	-9	hSpCas9	negative selection	862233
6394369	6394392	11	-	26627737	GBM cells	viability after 5 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.5608383574217259	[145]	[143,86]	7	hSpCas9	negative selection	862234
6390678	6390701	11	-	26627737	GBM cells	viability after 13 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	0.3907569406567355	[50]	[43,29]	5	hSpCas9	negative selection	944538
6390831	6390854	11	-	26627737	GBM cells	viability after 13 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.1660558053514447	[388]	[541,417]	9	hSpCas9	negative selection	944539
6391737	6391760	11	+	26627737	GBM cells	viability after 13 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.0076700870198567195	[48]	[34,19]	0	hSpCas9	negative selection	944546
6393310	6393333	11	+	26627737	GBM cells	viability after 13 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.3349087718062462	[142]	[27,32]	-8	hSpCas9	negative selection	944547
6394009	6394032	11	-	26627737	GBM cells	viability after 13 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-1.1707499358560276	[268]	[71,58]	-8	hSpCas9	negative selection	944548
6394369	6394392	11	-	26627737	GBM cells	viability after 13 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.5206951022838638	[145]	[95,127]	6	hSpCas9	negative selection	944549
6390678	6390701	11	-	26627737	GBM cells	viability after 21 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.17356182886928595	[50]	[22,25]	-1	hSpCas9	negative selection	1026853
6390831	6390854	11	-	26627737	GBM cells	viability after 21 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.1516224444668848	[388]	[480,458]	9	hSpCas9	negative selection	1026854
6391737	6391760	11	+	26627737	GBM cells	viability after 21 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	-0.6033626960387144	[48]	[16,17]	-5	hSpCas9	negative selection	1026861
6393310	6393333	11	+	26627737	GBM cells	viability after 21 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.8503940453856134	[142]	[40,44]	-6	hSpCas9	negative selection	1026862
6394009	6394032	11	-	26627737	GBM cells	viability after 21 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.30018799037850596	[268]	[125,111]	-3	hSpCas9	negative selection	1026863
6394369	6394392	11	-	26627737	GBM cells	viability after 21 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.780579984686533	[145]	[141,130]	7	hSpCas9	negative selection	1026864
6390678	6390701	11	-	26627737	RPE1	viability after 9 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	1.7763688225276781	[82]	[64,119]	8	hSpCas9	negative selection	1109168
6390831	6390854	11	-	26627737	RPE1	viability after 9 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.8340434366472151	[910]	[977,1066]	8	hSpCas9	negative selection	1109169
6391737	6391760	11	+	26627737	RPE1	viability after 9 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.3670505721945416	[342]	[103,182]	2	hSpCas9	negative selection	1109176
6393310	6393333	11	+	26627737	RPE1	viability after 9 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-3.0892596919250046	[406]	[0,32]	-9	hSpCas9	negative selection	1109177
6394009	6394032	11	-	26627737	RPE1	viability after 9 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.9438722754344205	[394]	[243,229]	6	hSpCas9	negative selection	1109178
6394369	6394392	11	-	26627737	RPE1	viability after 9 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	1.406879887312761	[183]	[88,234]	7	hSpCas9	negative selection	1109179
6390678	6390701	11	-	26627737	RPE1	viability after 12 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	1.7867874778829185	[82]	[74,78]	8	hSpCas9	negative selection	1191483
6390831	6390854	11	-	26627737	RPE1	viability after 12 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.6749853455120418	[910]	[799,761]	8	hSpCas9	negative selection	1191484
6391737	6391760	11	+	26627737	RPE1	viability after 12 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.5404434140513404	[342]	[134,132]	3	hSpCas9	negative selection	1191491
6393310	6393333	11	+	26627737	RPE1	viability after 12 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.7258834404305856	[406]	[0,66]	-8	hSpCas9	negative selection	1191492
6394009	6394032	11	-	26627737	RPE1	viability after 12 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.9688592004706629	[394]	[214,199]	6	hSpCas9	negative selection	1191493
6394369	6394392	11	-	26627737	RPE1	viability after 12 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	1.9043764674148198	[183]	[135,236]	8	hSpCas9	negative selection	1191494
6390678	6390701	11	-	26627737	RPE1	viability after 15 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	1.7274592220467317	[82]	[119,36]	8	hSpCas9	negative selection	1273798
6390831	6390854	11	-	26627737	RPE1	viability after 15 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.7445847143555004	[910]	[1197,540]	8	hSpCas9	negative selection	1273799
6391737	6391760	11	+	26627737	RPE1	viability after 15 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.8530013032397836	[342]	[188,161]	5	hSpCas9	negative selection	1273806
6393310	6393333	11	+	26627737	RPE1	viability after 15 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.3624088848094147	[406]	[0,86]	-7	hSpCas9	negative selection	1273807
6394009	6394032	11	-	26627737	RPE1	viability after 15 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.6663170173701758	[394]	[186,167]	4	hSpCas9	negative selection	1273808
6394369	6394392	11	-	26627737	RPE1	viability after 15 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	2.283655408216393	[183]	[228,276]	9	hSpCas9	negative selection	1273809
6390678	6390701	11	-	26627737	RPE1	viability after 18 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	1.2269846798736874	[82]	[64,38]	7	hSpCas9	negative selection	1356113
6390831	6390854	11	-	26627737	RPE1	viability after 18 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.8425384110876917	[910]	[1164,578]	8	hSpCas9	negative selection	1356114
6391737	6391760	11	+	26627737	RPE1	viability after 18 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.3546435960641867	[342]	[55,184]	2	hSpCas9	negative selection	1356121
6393310	6393333	11	+	26627737	RPE1	viability after 18 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.1677198550834753	[406]	[1,98]	-6	hSpCas9	negative selection	1356122
6394009	6394032	11	-	26627737	RPE1	viability after 18 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.6675470019805876	[394]	[163,174]	4	hSpCas9	negative selection	1356123
6394369	6394392	11	-	26627737	RPE1	viability after 18 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	2.6433551364379544	[183]	[156,473]	9	hSpCas9	negative selection	1356124
6390678	6390701	11	-	26627737	HeLa	viability after 8 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.9797984953680068	[87]	[28,3,0]	-9	hSpCas9	negative selection	1438428
6390831	6390854	11	-	26627737	HeLa	viability after 8 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	-0.11735018111678497	[792]	[361,224,372]	-1	hSpCas9	negative selection	1438429
6391737	6391760	11	+	26627737	HeLa	viability after 8 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	2.418456211414166	[54]	[110,198,73]	9	hSpCas9	negative selection	1438436
6393310	6393333	11	+	26627737	HeLa	viability after 8 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.609969443287135	[109]	[130,43,57]	5	hSpCas9	negative selection	1438437
6394009	6394032	11	-	26627737	HeLa	viability after 8 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.5042661868183502	[287]	[227,207,112]	4	hSpCas9	negative selection	1438438
6394369	6394392	11	-	26627737	HeLa	viability after 8 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.24200830212808822	[182]	[67,132,76]	2	hSpCas9	negative selection	1438439
6390678	6390701	11	-	26627737	HeLa	viability after 12 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.9108479781411294	[87]	[25,11,20]	-7	hSpCas9	negative selection	1520743
6390831	6390854	11	-	26627737	HeLa	viability after 12 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.029142600341415026	[792]	[307,366,323]	0	hSpCas9	negative selection	1520744
6391737	6391760	11	+	26627737	HeLa	viability after 12 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	1.4239388767463816	[54]	[57,106,12]	8	hSpCas9	negative selection	1520751
6393310	6393333	11	+	26627737	HeLa	viability after 12 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-3.221265560167411	[109]	[10,2,0]	-9	hSpCas9	negative selection	1520752
6394009	6394032	11	-	26627737	HeLa	viability after 12 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.6849654253071215	[287]	[179,197,194]	5	hSpCas9	negative selection	1520753
6394369	6394392	11	-	26627737	HeLa	viability after 12 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.5320148251530988	[182]	[115,73,141]	4	hSpCas9	negative selection	1520754
6390678	6390701	11	-	26627737	HeLa	viability after 15 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.3241698901579797	[87]	[6,33,0]	-8	hSpCas9	negative selection	1603058
6390831	6390854	11	-	26627737	HeLa	viability after 15 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.13280832626951367	[792]	[287,320,461]	1	hSpCas9	negative selection	1603059
6391737	6391760	11	+	26627737	HeLa	viability after 15 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.7709767233856999	[54]	[0,52,62]	6	hSpCas9	negative selection	1603066
6393310	6393333	11	+	26627737	HeLa	viability after 15 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.9430438073771374	[109]	[115,114,21]	7	hSpCas9	negative selection	1603067
6394009	6394032	11	-	26627737	HeLa	viability after 15 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.09540756532368455	[287]	[128,89,109]	-1	hSpCas9	negative selection	1603068
6394369	6394392	11	-	26627737	HeLa	viability after 15 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.6023679351466947	[182]	[76,134,128]	5	hSpCas9	negative selection	1603069
6390678	6390701	11	-	26627737	HeLa	viability after 18 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.1495489276059545	[87]	[5,30,0]	-7	hSpCas9	negative selection	1685373
6390831	6390854	11	-	26627737	HeLa	viability after 18 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.11408950968016818	[792]	[176,274,461]	1	hSpCas9	negative selection	1685374
6391737	6391760	11	+	26627737	HeLa	viability after 18 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.8247191304557941	[54]	[0,46,62]	6	hSpCas9	negative selection	1685381
6393310	6393333	11	+	26627737	HeLa	viability after 18 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.8467721060720298	[109]	[67,93,21]	6	hSpCas9	negative selection	1685382
6394009	6394032	11	-	26627737	HeLa	viability after 18 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.0591860256521074	[287]	[89,76,109]	0	hSpCas9	negative selection	1685383
6394369	6394392	11	-	26627737	HeLa	viability after 18 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.6070079342462789	[182]	[52,110,128]	5	hSpCas9	negative selection	1685384
6390678	6390701	11	-	26627737	HCT116	viability after 6 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	1.0206580593337709	[170]	[147,2]	5	hSpCas9	negative selection	1767688
6390831	6390854	11	-	26627737	HCT116	viability after 6 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.4858933611490829	[1087]	[361,171]	2	hSpCas9	negative selection	1767689
6391737	6391760	11	+	26627737	HCT116	viability after 6 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.1510163450249964	[153]	[71,1]	0	hSpCas9	negative selection	1767696
6393310	6393333	11	+	26627737	HCT116	viability after 6 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.6943844030031148	[360]	[3,24]	-7	hSpCas9	negative selection	1767697
6394009	6394032	11	-	26627737	HCT116	viability after 6 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.6212550987794404	[718]	[441,25]	3	hSpCas9	negative selection	1767698
6394369	6394392	11	-	26627737	HCT116	viability after 6 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	1.3267504043060225	[356]	[7,213]	7	hSpCas9	negative selection	1767699
6390678	6390701	11	-	26627737	HCT116	viability after 8 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.7670425320916197	[119]	[20,35,58]	-7	hSpCas9	negative selection	1850003
6390831	6390854	11	-	26627737	HCT116	viability after 8 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.31583060657996154	[405]	[385,228,222]	3	hSpCas9	negative selection	1850004
6391737	6391760	11	+	26627737	HCT116	viability after 8 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	-0.4181314923463775	[116]	[8,82,51]	-5	hSpCas9	negative selection	1850011
6393310	6393333	11	+	26627737	HCT116	viability after 8 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.11733441731990524	[191]	[96,134,111]	1	hSpCas9	negative selection	1850012
6394009	6394032	11	-	26627737	HCT116	viability after 8 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-1.2267884596161462	[451]	[88,45,182]	-9	hSpCas9	negative selection	1850013
6394369	6394392	11	-	26627737	HCT116	viability after 8 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.1713142920957602	[148]	[57,146,71]	2	hSpCas9	negative selection	1850014
6390678	6390701	11	-	26627737	HCT116	viability after 9 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.5079969483606135	[170]	[11,47]	-4	hSpCas9	negative selection	1932318
6390831	6390854	11	-	26627737	HCT116	viability after 9 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.3146415684294549	[1087]	[281,423]	2	hSpCas9	negative selection	1932319
6391737	6391760	11	+	26627737	HCT116	viability after 9 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.22451901699145527	[153]	[18,70]	1	hSpCas9	negative selection	1932326
6393310	6393333	11	+	26627737	HCT116	viability after 9 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.08994569585845735	[360]	[115,91]	0	hSpCas9	negative selection	1932327
6394009	6394032	11	-	26627737	HCT116	viability after 9 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.2408312331711305	[718]	[313,157]	1	hSpCas9	negative selection	1932328
6394369	6394392	11	-	26627737	HCT116	viability after 9 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	-3.2232741732052217	[356]	[12,7]	-9	hSpCas9	negative selection	1932329
6390678	6390701	11	-	26627737	HCT116	viability after 12 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	0.24943969989608927	[119]	[25,107,95]	2	hSpCas9	negative selection	2014633
6390831	6390854	11	-	26627737	HCT116	viability after 12 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.06878653773838361	[405]	[169,261,244]	0	hSpCas9	negative selection	2014634
6391737	6391760	11	+	26627737	HCT116	viability after 12 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.5642510784752343	[116]	[139,72,54]	5	hSpCas9	negative selection	2014641
6393310	6393333	11	+	26627737	HCT116	viability after 12 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.34418966764439063	[191]	[66,97,74]	-4	hSpCas9	negative selection	2014642
6394009	6394032	11	-	26627737	HCT116	viability after 12 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.2669634181283877	[451]	[241,101,241]	-3	hSpCas9	negative selection	2014643
6394369	6394392	11	-	26627737	HCT116	viability after 12 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.42960444029525713	[148]	[91,122,102]	4	hSpCas9	negative selection	2014644
6390678	6390701	11	-	26627737	HCT116	viability after 15 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.41792852418226856	[119]	[12,80,55]	-4	hSpCas9	negative selection	2096948
6390831	6390854	11	-	26627737	HCT116	viability after 15 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.3230488724379291	[405]	[263,259,346]	3	hSpCas9	negative selection	2096949
6391737	6391760	11	+	26627737	HCT116	viability after 15 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	1.085717862786926	[116]	[90,224,105]	8	hSpCas9	negative selection	2096956
6393310	6393333	11	+	26627737	HCT116	viability after 15 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.2594333830072514	[191]	[76,145,51]	-3	hSpCas9	negative selection	2096957
6394009	6394032	11	-	26627737	HCT116	viability after 15 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.2424845615509787	[451]	[113,192,336]	-3	hSpCas9	negative selection	2096958
6394369	6394392	11	-	26627737	HCT116	viability after 15 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	-0.17158606465270387	[148]	[27,110,82]	-2	hSpCas9	negative selection	2096959
6390678	6390701	11	-	26627737	HCT116	viability after 18 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.15345321712853	[119]	[0,46,28]	-8	hSpCas9	negative selection	2179263
6390831	6390854	11	-	26627737	HCT116	viability after 18 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.0818825363005139	[405]	[188,225,206]	0	hSpCas9	negative selection	2179264
6391737	6391760	11	+	26627737	HCT116	viability after 18 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.5824452422596836	[116]	[49,133,65]	5	hSpCas9	negative selection	2179271
6393310	6393333	11	+	26627737	HCT116	viability after 18 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.002367526444375878	[191]	[52,168,48]	0	hSpCas9	negative selection	2179272
6394009	6394032	11	-	26627737	HCT116	viability after 18 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.5927719278599254	[451]	[72,145,218]	-5	hSpCas9	negative selection	2179273
6394369	6394392	11	-	26627737	HCT116	viability after 18 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	-0.03196232694292056	[148]	[0,84,126]	0	hSpCas9	negative selection	2179274
6391771	6391794	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	0.01883472128534293	[3,3]	[3,1]	0	hSpCas9	positive selection	3022277
6391752	6391775	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	-0.23456730713397006	[2,2]	[2,1]	-3	hSpCas9	positive selection	3022278
6391908	6391931	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	0.39884666191529017	[3,2]	[2,4]	8	hSpCas9	positive selection	3022279
6391871	6391894	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-1.5186804506589953	[2,2]	[0,0]	-9	hSpCas9	positive selection	3022280
6391771	6391794	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	0.529443048267236	[3,3]	[3,3]	8	hSpCas9	positive selection	3090135
6391752	6391775	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	0.2632623124204627	[2,2]	[2,1]	4	hSpCas9	positive selection	3090136
6391908	6391931	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	0.008324785047728225	[3,3]	[3,1]	0	hSpCas9	positive selection	3090137
6391871	6391894	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.37939021820413577	[2,2]	[2,0]	-5	hSpCas9	positive selection	3090138
6391904	6391927		+	24336571	A375	resistance to PLX after 7 days	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.14727378309669237	[27,30]	[31,32]	5	hSpCas9	positive selection	3146226
6393310	6393333		+	24336571	A375	resistance to PLX after 7 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.04731639202520577	[14,15]	[15,13]	-1	hSpCas9	positive selection	3146227
6393358	6393381		+	24336571	A375	resistance to PLX after 7 days	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	0.43117750062166604	[8,9]	[11,12]	9	hSpCas9	positive selection	3146228
6391876	6391899		-	24336571	A375	resistance to PLX after 7 days	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	0.2776502012020913	[5,6]	[6,9]	7	hSpCas9	positive selection	3146229
6391904	6391927		+	24336571	A375	resistance to PLX after 14 days	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.14745636258000716	[23,25]	[13,10]	1	hSpCas9	positive selection	3204019
6393310	6393333		+	24336571	A375	resistance to PLX after 14 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.25458419067386645	[13,9]	[4,7]	2	hSpCas9	positive selection	3204020
6393358	6393381		+	24336571	A375	resistance to PLX after 14 days	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	0.07789035204250105	[7,10]	[3,4]	0	hSpCas9	positive selection	3204021
6391876	6391899		-	24336571	A375	resistance to PLX after 14 days	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	0.15526041627687392	[5,10]	[3,3]	1	hSpCas9	positive selection	3204022
6391904	6391927		+	24336571	A375	viability after 7 days	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.3696977959331724	[23]	[27,30]	5	hSpCas9	negative selection	3261812
6393310	6393333		+	24336571	A375	viability after 7 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.7426407747757848	[27]	[14,15]	-8	hSpCas9	negative selection	3261813
6393358	6393381		+	24336571	A375	viability after 7 days	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	0.6260576970435836	[5]	[8,9]	8	hSpCas9	negative selection	3261814
6391876	6391899		-	24336571	A375	viability after 7 days	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	-1.01766848385135	[14]	[5,6]	-9	hSpCas9	negative selection	3261815
6391904	6391927		+	24336571	A375	viability after 14 days	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.1412182803747284	[23]	[23,25]	1	hSpCas9	negative selection	3319605
6393310	6393333		+	24336571	A375	viability after 14 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.0678372069339415	[27]	[13,9]	-8	hSpCas9	negative selection	3319606
6393358	6393381		+	24336571	A375	viability after 14 days	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	0.6687059986173411	[5]	[7,10]	8	hSpCas9	negative selection	3319607
6391876	6391899		-	24336571	A375	viability after 14 days	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	-0.7224438741301797	[14]	[5,10]	-7	hSpCas9	negative selection	3319608
6391904	6391927	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	-0.04645453673126785	[157,157]	[0,0]	0	hSpCas9	positive selection	3393947
6393608	6393631	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	-0.714217342504937	[250,250]	[0,0]	-5	hSpCas9	positive selection	3393948
6393679	6393702	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-1.3901322150090851	[400,400]	[0,0]	-8	hSpCas9	positive selection	3393949
6391771	6391794	11	-	26780180	HT29	viability (Avana library 4 designs)	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	1.28067807950089	[]	[]	5	hSpCas9	negative selection	3460863
6391752	6391775	11	-	26780180	HT29	viability (Avana library 4 designs)	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	2.76390125245338	[]	[]	8	hSpCas9	negative selection	3460864
6391908	6391931	11	-	26780180	HT29	viability (Avana library 4 designs)	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	0.505510926560072	[]	[]	2	hSpCas9	negative selection	3460865
6391871	6391894	11	-	26780180	HT29	viability (Avana library 4 designs)	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	2.22858960897915	[]	[]	7	hSpCas9	negative selection	3460866
6391908	6391931	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	5.62109227875665	[]	[]	8	hSpCas9	negative selection	3561442
6391771	6391794	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	2.94364819127762	[]	[]	4	hSpCas9	negative selection	3561443
6391752	6391775	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	2.31173663080817	[]	[]	3	hSpCas9	negative selection	3561444
6391871	6391894	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-11.6168659236301	[]	[]	-8	hSpCas9	negative selection	3561445
6390813	6390836	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTACATCGCATAGTGCCCCGG	SMPD1	ENSG00000166311	-2.11930580419386	[]	[]	-3	hSpCas9	negative selection	3561446
6391482	6391505	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGAGGATGACATGGTGGAGG	SMPD1	ENSG00000166311	1.95402416781722	[]	[]	3	hSpCas9	negative selection	3561447
6391908	6391931	11	-	26780180	A375	viability (Avana lentiGuide)	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	-1.2192105261989	[]	[]	-2	hSpCas9	negative selection	3670101
6391771	6391794	11	-	26780180	A375	viability (Avana lentiGuide)	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	0.413871153261915	[]	[]	0	hSpCas9	negative selection	3670102
6391752	6391775	11	-	26780180	A375	viability (Avana lentiGuide)	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	-1.45938853706228	[]	[]	-2	hSpCas9	negative selection	3670103
6391871	6391894	11	-	26780180	A375	viability (Avana lentiGuide)	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.8050463135174	[]	[]	1	hSpCas9	negative selection	3670104
6390813	6390836	11	+	26780180	A375	viability (Avana lentiGuide)	GGTTACATCGCATAGTGCCCCGG	SMPD1	ENSG00000166311	3.15451852784902	[]	[]	3	hSpCas9	negative selection	3670105
6391482	6391505	11	+	26780180	A375	viability (Avana lentiGuide)	CTTTGAGGATGACATGGTGGAGG	SMPD1	ENSG00000166311	-4.30272678743753	[]	[]	-7	hSpCas9	negative selection	3670106
6391908	6391931	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	0.2162820751186657	[4]	[5,4]	6	hSpCas9	positive selection	3778708
6391771	6391794	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	0.40653006080650306	[3]	[5,4]	9	hSpCas9	positive selection	3778709
6391752	6391775	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	0.09275676099335758	[3]	[5,2]	2	hSpCas9	positive selection	3778710
6391871	6391894	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.6678623682922712	[5]	[4,1]	-7	hSpCas9	positive selection	3778711
6390813	6390836	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTACATCGCATAGTGCCCCGG	SMPD1	ENSG00000166311	0.012301404008776773	[4]	[4,4]	0	hSpCas9	positive selection	3778712
6391482	6391505	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGAGGATGACATGGTGGAGG	SMPD1	ENSG00000166311	0.20151129019023242	[6]	[6,6]	5	hSpCas9	positive selection	3778713
6391908	6391931	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCCAGACATCATGTGCGGGG	SMPD1	ENSG00000166311	-0.0028777459596305496	[5]	[3,4]	0	hSpCas9	positive selection	3887315
6391771	6391794	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCTGGCCGGGATGCGGGCGG	SMPD1	ENSG00000166311	-0.2644637213011847	[4]	[3,2]	-4	hSpCas9	positive selection	3887316
6391752	6391775	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGCAGGCCAGAACCCCGGCGG	SMPD1	ENSG00000166311	-0.437001206955285	[4]	[2,2]	-5	hSpCas9	positive selection	3887317
6391871	6391894	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.5254418899535082	[4]	[2,0]	-6	hSpCas9	positive selection	3887318
6390813	6390836	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTACATCGCATAGTGCCCCGG	SMPD1	ENSG00000166311	0.017983483785155713	[6]	[5,4]	0	hSpCas9	positive selection	3887319
6391482	6391505	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGAGGATGACATGGTGGAGG	SMPD1	ENSG00000166311	0.16746886477666478	[6]	[7,5]	4	hSpCas9	positive selection	3887320
6391904	6391927	11	+	26780180	A375	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.55135104358551	[]	[]	1	hSpCas9	negative selection	3997412
6394021	6394044	11	-	26780180	A375	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	1.14703059634745	[]	[]	6	hSpCas9	negative selection	3997413
6392142	6392165	11	-	26780180	A375	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	2.25207550152899	[]	[]	9	hSpCas9	negative selection	3997414
6393310	6393333	11	+	26780180	A375	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	1.86214323140913	[]	[]	9	hSpCas9	negative selection	3997415
6393608	6393631	11	+	26780180	A375	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.736448238747699	[]	[]	2	hSpCas9	negative selection	3997416
6393679	6393702	11	-	26780180	A375	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.750628874887112	[]	[]	2	hSpCas9	negative selection	3997417
6391904	6391927	11	+	26780180	HT29	viability (GeCKOv2 library)	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.257081444755135	[]	[]	0	hSpCas9	negative selection	4105378
6394021	6394044	11	-	26780180	HT29	viability (GeCKOv2 library)	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.793064976483074	[]	[]	3	hSpCas9	negative selection	4105379
6392142	6392165	11	-	26780180	HT29	viability (GeCKOv2 library)	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	2.72921004031855	[]	[]	9	hSpCas9	negative selection	4105380
6393310	6393333	11	+	26780180	HT29	viability (GeCKOv2 library)	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.847720534255302	[]	[]	3	hSpCas9	negative selection	4105381
6393608	6393631	11	+	26780180	HT29	viability (GeCKOv2 library)	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.147081493565096	[]	[]	0	hSpCas9	negative selection	4105382
6393679	6393702	11	-	26780180	HT29	viability (GeCKOv2 library)	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.544345702998887	[]	[]	1	hSpCas9	negative selection	4105383
6391904	6391927	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.15927125138533477	[4]	[3,3]	4	hSpCas9	positive selection	4172313
6393310	6393333	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.1135388106994916	[3]	[2,2]	3	hSpCas9	positive selection	4172314
6393358	6393381	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	-0.06587252636989482	[5]	[4,1]	-1	hSpCas9	positive selection	4172315
6391876	6391899	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	0.5101797878591139	[2]	[2,1]	9	hSpCas9	positive selection	4172316
6391904	6391927	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	-0.000767642028293769	[4]	[3,4,0,0]	0	hSpCas9	positive selection	4236335
6393310	6393333	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.7247555961028613	[5]	[5,2,1,3]	5	hSpCas9	positive selection	4236336
6393358	6393381	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCAGGCTGCTGAGGATCGAGG	SMPD1	ENSG00000166311	-0.042829915681189185	[4]	[3,2,2,0]	0	hSpCas9	positive selection	4236337
6391876	6391899	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCAGTACACCATATCAAAAGG	SMPD1	ENSG00000166311	-0.2241784365997043	[3]	[0,2,1,0]	-3	hSpCas9	positive selection	4236338
6393310	6393333	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.8286107953931346	[2]	[3,4]	9	hSpCas9	positive selection	4299432
6392142	6392165	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.5774754320611535	[3]	[2,0]	-8	hSpCas9	positive selection	4299433
6394021	6394044	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.1651432148808025	[3]	[3,1]	-3	hSpCas9	positive selection	4299434
6391904	6391927	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.2573675306834578	[3]	[3,3]	5	hSpCas9	positive selection	4363685
6393608	6393631	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.2559751430928186	[2]	[3,1]	5	hSpCas9	positive selection	4363686
6393679	6393702	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.31582266058297775	[3]	[3,3]	6	hSpCas9	positive selection	4363687
6390806	6390828	11	-	27760321	OCIAML3	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.7687350276071914	[680,636]	[283,326]	-6	hSpCas9	negative selection	4441527
6390888	6390910	11	+	27760321	OCIAML3	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.04660721497788789	[643,573]	[466,451]	0	hSpCas9	negative selection	4441528
6391388	6391410	11	+	27760321	OCIAML3	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.2201034718204935	[1015,925]	[897,865]	2	hSpCas9	negative selection	4441529
6391453	6391475	11	-	27760321	OCIAML3	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.7991255466545237	[823,691]	[770,1361]	8	hSpCas9	negative selection	4441530
6391786	6391808	11	-	27760321	OCIAML3	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.38141867441959	[999,764]	[843,954]	4	hSpCas9	negative selection	4441531
6390806	6390828	11	-	27760321	OCIAML2	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.8426100430171298	[680,636]	[274,326]	-7	hSpCas9	negative selection	4524990
6390888	6390910	11	+	27760321	OCIAML2	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.03006852578023611	[643,573]	[426,553]	0	hSpCas9	negative selection	4524991
6391388	6391410	11	+	27760321	OCIAML2	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.11072526487475987	[1015,925]	[700,1040]	1	hSpCas9	negative selection	4524992
6391453	6391475	11	-	27760321	OCIAML2	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.19344568577916332	[823,691]	[587,843]	2	hSpCas9	negative selection	4524993
6391786	6391808	11	-	27760321	OCIAML2	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.23255446380635703	[999,764]	[736,957]	3	hSpCas9	negative selection	4524994
6390806	6390828	11	-	27760321	MV411	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.15946276722903308	[680,636]	[365,424]	-1	hSpCas9	negative selection	4608453
6390888	6390910	11	+	27760321	MV411	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.04999622309970381	[643,573]	[239,678]	0	hSpCas9	negative selection	4608454
6391388	6391410	11	+	27760321	MV411	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.2947992051247539	[1015,925]	[815,739]	2	hSpCas9	negative selection	4608455
6391453	6391475	11	-	27760321	MV411	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.6979267555554525	[823,691]	[908,656]	5	hSpCas9	negative selection	4608456
6391786	6391808	11	-	27760321	MV411	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.3315443574109158	[999,764]	[749,692]	2	hSpCas9	negative selection	4608457
6390806	6390828	11	-	27760321	HL60	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.24328146538247175	[680,636]	[422,488]	-3	hSpCas9	negative selection	4691916
6390888	6390910	11	+	27760321	HL60	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.0717324160434708	[643,573]	[411,536]	-1	hSpCas9	negative selection	4691917
6391388	6391410	11	+	27760321	HL60	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.0846552014230817	[1015,925]	[879,798]	1	hSpCas9	negative selection	4691918
6391453	6391475	11	-	27760321	HL60	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.24415782268889874	[823,691]	[764,693]	3	hSpCas9	negative selection	4691919
6391786	6391808	11	-	27760321	HL60	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	-0.3357926847451086	[999,764]	[610,519]	-4	hSpCas9	negative selection	4691920
6390806	6390828	11	-	27760321	HT1080	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.5423601994311122	[636,496]	[135,175]	-2	hSpCas9	negative selection	4775379
6390888	6390910	11	+	27760321	HT1080	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	1.1501574553816676	[573,447]	[457,444]	6	hSpCas9	negative selection	4775380
6391388	6391410	11	+	27760321	HT1080	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.9147044562898583	[925,722]	[549,694]	5	hSpCas9	negative selection	4775381
6391453	6391475	11	-	27760321	HT1080	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	1.271863675963897	[691,539]	[909,244]	7	hSpCas9	negative selection	4775382
6391786	6391808	11	-	27760321	HT1080	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	-0.15377273182522	[764,596]	[124,373]	0	hSpCas9	negative selection	4775383
6390806	6390828	11	-	27760321	HT29	viability after 7 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.7511380926794577	[636,496]	[464,364,471]	-8	hSpCas9	negative selection	4858842
6390888	6390910	11	+	27760321	HT29	viability after 7 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.07069034286741949	[573,447]	[556,420,1059]	1	hSpCas9	negative selection	4858843
6391388	6391410	11	+	27760321	HT29	viability after 7 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.3061657499265259	[925,722]	[1044,895,662]	-4	hSpCas9	negative selection	4858844
6391453	6391475	11	-	27760321	HT29	viability after 7 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.2894810779178053	[691,539]	[1183,1120,638]	4	hSpCas9	negative selection	4858845
6391786	6391808	11	-	27760321	HT29	viability after 7 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.6957904093033881	[764,596]	[1489,1391,1381]	9	hSpCas9	negative selection	4858846
6390806	6390828	11	-	27760321	HT29	viability after 25 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.13205616200618975	[636,496]	[716,620,407]	-1	hSpCas9	negative selection	4942305
6390888	6390910	11	+	27760321	HT29	viability after 25 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.10949211613609372	[573,447]	[435,425,793]	-1	hSpCas9	negative selection	4942306
6391388	6391410	11	+	27760321	HT29	viability after 25 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.17091729959713797	[925,722]	[855,782,1611]	1	hSpCas9	negative selection	4942307
6391453	6391475	11	-	27760321	HT29	viability after 25 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.2220363972881666	[691,539]	[653,855,978]	2	hSpCas9	negative selection	4942308
6391786	6391808	11	-	27760321	HT29	viability after 25 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.8039869293134	[764,596]	[1111,1470,1523]	8	hSpCas9	negative selection	4942309
6390806	6390828	11	-	27760321	HT29	viability after 22 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.33162783421158837	[636,496]	[498,558,504]	-3	hSpCas9	negative selection	5025768
6390888	6390910	11	+	27760321	HT29	viability after 22 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.21583149597871265	[573,447]	[728,644,682]	2	hSpCas9	negative selection	5025769
6391388	6391410	11	+	27760321	HT29	viability after 22 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.28229009658403625	[925,722]	[1192,1188,1093]	3	hSpCas9	negative selection	5025770
6391453	6391475	11	-	27760321	HT29	viability after 22 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.7113230887480334	[691,539]	[1377,957,1155]	7	hSpCas9	negative selection	5025771
6391786	6391808	11	-	27760321	HT29	viability after 22 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.8296051164523387	[764,596]	[1681,1283,1221]	8	hSpCas9	negative selection	5025772
6390806	6390828	11	-	27760321	HT29	viability after 19 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.18452929899171494	[636,496]	[705,379,636]	-2	hSpCas9	negative selection	5109231
6390888	6390910	11	+	27760321	HT29	viability after 19 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.20003442931978688	[573,447]	[366,793,355]	-2	hSpCas9	negative selection	5109232
6391388	6391410	11	+	27760321	HT29	viability after 19 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.3405426264447855	[925,722]	[1059,1573,942]	3	hSpCas9	negative selection	5109233
6391453	6391475	11	-	27760321	HT29	viability after 19 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.16604248688941137	[691,539]	[816,1126,442]	1	hSpCas9	negative selection	5109234
6391786	6391808	11	-	27760321	HT29	viability after 19 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	1.080060221779255	[764,596]	[1847,1393,1714]	9	hSpCas9	negative selection	5109235
6390806	6390828	11	-	27760321	HT29	viability after 16 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.7955818209269117	[636,496]	[466,399,237]	-6	hSpCas9	negative selection	5192694
6390888	6390910	11	+	27760321	HT29	viability after 16 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.24103564444697756	[573,447]	[485,789,729]	2	hSpCas9	negative selection	5192695
6391388	6391410	11	+	27760321	HT29	viability after 16 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.20829896496319933	[925,722]	[846,676,878]	-2	hSpCas9	negative selection	5192696
6391453	6391475	11	-	27760321	HT29	viability after 16 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.24628561586699538	[691,539]	[1138,688,657]	2	hSpCas9	negative selection	5192697
6391786	6391808	11	-	27760321	HT29	viability after 16 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.8179356573524711	[764,596]	[1586,1390,1072]	8	hSpCas9	negative selection	5192698
6390806	6390828	11	-	27760321	HT29	viability after 13 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.6484301626337045	[636,496]	[566,467,234]	-6	hSpCas9	negative selection	5276157
6390888	6390910	11	+	27760321	HT29	viability after 13 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	-0.09900719564903548	[573,447]	[474,468,706]	-1	hSpCas9	negative selection	5276158
6391388	6391410	11	+	27760321	HT29	viability after 13 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.11901867792396703	[925,722]	[1071,1105,943]	1	hSpCas9	negative selection	5276159
6391453	6391475	11	-	27760321	HT29	viability after 13 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.25915127247092473	[691,539]	[1027,900,648]	3	hSpCas9	negative selection	5276160
6391786	6391808	11	-	27760321	HT29	viability after 13 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.6513677055788444	[764,596]	[1743,954,1034]	8	hSpCas9	negative selection	5276161
6390806	6390828	11	-	27760321	HT29	viability after 10 days	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-0.12150433390792559	[636,496]	[518,907,534]	-2	hSpCas9	negative selection	5359620
6390888	6390910	11	+	27760321	HT29	viability after 10 days	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.19823998298538092	[573,447]	[866,413,901]	2	hSpCas9	negative selection	5359621
6391388	6391410	11	+	27760321	HT29	viability after 10 days	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.009173823522824698	[925,722]	[1133,973,998]	0	hSpCas9	negative selection	5359622
6391453	6391475	11	-	27760321	HT29	viability after 10 days	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.35727958889038625	[691,539]	[1028,834,1084]	5	hSpCas9	negative selection	5359623
6391786	6391808	11	-	27760321	HT29	viability after 10 days	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.6708306240079279	[764,596]	[1370,1393,1297]	8	hSpCas9	negative selection	5359624
6390806	6390828	11	-	27760321	MOLM13	viability	CTATGCGATGTAACCTGGCAGG	SMPD1	ENSG00000166311	-1.0505849814339103	[680,636]	[332,48]	-6	hSpCas9	negative selection	5443083
6390888	6390910	11	+	27760321	MOLM13	viability	TATTCACCGCCATCAACCTCGG	SMPD1	ENSG00000166311	0.18181805696212777	[643,573]	[305,459]	1	hSpCas9	negative selection	5443084
6391388	6391410	11	+	27760321	MOLM13	viability	AACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.25288251344859713	[1015,925]	[418,493]	-2	hSpCas9	negative selection	5443085
6391453	6391475	11	-	27760321	MOLM13	viability	CAATGGATTGGCACACGGCAGG	SMPD1	ENSG00000166311	0.6639236877686503	[823,691]	[1078,330]	4	hSpCas9	negative selection	5443086
6391786	6391808	11	-	27760321	MOLM13	viability	CGCCCCAGTATCCGGCACCTGG	SMPD1	ENSG00000166311	0.1219450492718046	[999,764]	[689,407]	0	hSpCas9	negative selection	5443087
6390491	6390514	11	+	27661255	K562	viability	GAAGGGTAATCGGGTGTCCCCGG	SMPD1	ENSG00000166311	-0.03482171726524719	[1237,1219]	[1146,797]	-1	dCas9-KRAB	negative selection	5513047
6390909	6390932	11	+	27661255	K562	viability	GGCTGAAGGTGAGCACTGAAGGG	SMPD1	ENSG00000166311	0.31996289578973225	[396,338]	[428,315]	8	dCas9-KRAB	negative selection	5513048
6390943	6390966	11	+	27661255	K562	viability	GGAGGCCGAAAGGAGTGCTGGGG	SMPD1	ENSG00000166311	0.1335516909941309	[752,836]	[751,646]	4	dCas9-KRAB	negative selection	5513049
6390465	6390488	11	-	27661255	K562	viability	GTAGTCGGCTGACTGCTCCGCGG	SMPD1	ENSG00000166311	0.008227678203557742	[2115,2263]	[1902,1632]	0	dCas9-KRAB	negative selection	5513050
6390678	6390701	11	-	27661255	K562	viability	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.2887119803831534	[384,404]	[263,252]	-6	dCas9-KRAB	negative selection	5513051
6393310	6393333	11	+	27260156	BXPC3	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.057254925842604235	[416]	[429,378,518,496]	1	hSpCas9	negative selection	5571892
6392142	6392165	11	-	27260156	BXPC3	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.28722135461081505	[571]	[457,516,533,444]	-6	hSpCas9	negative selection	5571893
6394021	6394044	11	-	27260156	BXPC3	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.11298536469460863	[893]	[767,658,873,1216]	-3	hSpCas9	negative selection	5571894
6391904	6391927	11	+	27260156	BXPC3	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.06797941446908062	[982]	[1086,1026,967,1239]	1	hSpCas9	negative selection	5636145
6393608	6393631	11	+	27260156	BXPC3	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3903076314994184	[427]	[569,564,596,616]	8	hSpCas9	negative selection	5636146
6393679	6393702	11	-	27260156	BXPC3	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.035590965560969856	[808]	[725,932,781,1053]	0	hSpCas9	negative selection	5636147
6393310	6393333	11	+	27260156	A673	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.18082281840032458	[416]	[743,465,596,479]	4	hSpCas9	negative selection	5693143
6392142	6392165	11	-	27260156	A673	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.3092713358643016	[571]	[536,549,572,553]	-6	hSpCas9	negative selection	5693144
6394021	6394044	11	-	27260156	A673	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.019208017200583516	[893]	[1255,986,934,1083]	0	hSpCas9	negative selection	5693145
6391904	6391927	11	+	27260156	A673	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.20674197694234597	[982]	[1535,1317,1254,1358]	5	hSpCas9	negative selection	5757396
6393608	6393631	11	+	27260156	A673	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.2679229071889506	[427]	[731,550,616,586]	6	hSpCas9	negative selection	5757397
6393679	6393702	11	-	27260156	A673	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.1137832205225372	[808]	[1205,870,1015,1136]	2	hSpCas9	negative selection	5757398
6393310	6393333	11	+	27260156	A375	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.27723821888843697	[416]	[424,750,642,563]	4	hSpCas9	negative selection	5814394
6392142	6392165	11	-	27260156	A375	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.043850541407453425	[571]	[814,659,610,521]	0	hSpCas9	negative selection	5814395
6394021	6394044	11	-	27260156	A375	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.415763661772069	[893]	[770,848,890,642]	-5	hSpCas9	negative selection	5814396
6391904	6391927	11	+	27260156	A375	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.29028299603424657	[982]	[935,1521,1487,1647]	4	hSpCas9	negative selection	5878647
6393608	6393631	11	+	27260156	A375	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.7213532017227233	[427]	[778,1038,836,684]	9	hSpCas9	negative selection	5878648
6393679	6393702	11	-	27260156	A375	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.24381340778242222	[808]	[1044,1303,1126,1030]	3	hSpCas9	negative selection	5878649
6393310	6393333	11	+	27260156	COLO741	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.20469612762238604	[416]	[407,490,480]	-4	hSpCas9	negative selection	5935645
6392142	6392165	11	-	27260156	COLO741	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.7488450965063924	[571]	[469,294,533]	-9	hSpCas9	negative selection	5935646
6394021	6394044	11	-	27260156	COLO741	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.030082797998003397	[893]	[1004,1217,1120]	0	hSpCas9	negative selection	5935647
6391904	6391927	11	+	27260156	COLO741	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.23220177592158087	[982]	[1625,1443,1372]	5	hSpCas9	negative selection	5999898
6393608	6393631	11	+	27260156	COLO741	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3677563182980782	[427]	[755,664,698]	7	hSpCas9	negative selection	5999899
6393679	6393702	11	-	27260156	COLO741	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.2231483914563338	[808]	[1612,1100,955]	5	hSpCas9	negative selection	5999900
6393310	6393333	11	+	27260156	CAL120	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.4426674738255273	[416]	[284,481,363]	-6	hSpCas9	negative selection	6056896
6392142	6392165	11	-	27260156	CAL120	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	0.14131934732590484	[571]	[1477,583,403]	2	hSpCas9	negative selection	6056897
6394021	6394044	11	-	27260156	CAL120	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.28050975361292985	[893]	[1270,626,902]	-4	hSpCas9	negative selection	6056898
6391904	6391927	11	+	27260156	CAL120	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.4090827575891647	[982]	[2110,1414,1422]	6	hSpCas9	negative selection	6121149
6393608	6393631	11	+	27260156	CAL120	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.41782808397435955	[427]	[795,754,597]	6	hSpCas9	negative selection	6121150
6393679	6393702	11	-	27260156	CAL120	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.20172446380659437	[808]	[1726,867,966]	3	hSpCas9	negative selection	6121151
6393310	6393333	11	+	27260156	CADOES1	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.1460333281124757	[416]	[467,585,382,273]	2	hSpCas9	negative selection	6178147
6392142	6392165	11	-	27260156	CADOES1	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	0.143620510214568	[571]	[641,578,479,651]	2	hSpCas9	negative selection	6178148
6394021	6394044	11	-	27260156	CADOES1	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.46024858122587	[893]	[582,692,529,611]	-7	hSpCas9	negative selection	6178149
6391904	6391927	11	+	27260156	CADOES1	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.4325412715987802	[982]	[1066,1165,1512,1187]	7	hSpCas9	negative selection	6242400
6393608	6393631	11	+	27260156	CADOES1	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.40142431189043226	[427]	[477,546,481,598]	6	hSpCas9	negative selection	6242401
6393679	6393702	11	-	27260156	CADOES1	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.16163686221110862	[808]	[946,807,849,757]	2	hSpCas9	negative selection	6242402
6393310	6393333	11	+	27260156	EWS502	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.01018888583881597	[416]	[629,403,296,421]	0	hSpCas9	negative selection	6299398
6392142	6392165	11	-	27260156	EWS502	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.309941568509245	[571]	[490,526,355,581]	-5	hSpCas9	negative selection	6299399
6394021	6394044	11	-	27260156	EWS502	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.10160740936626556	[893]	[760,909,870,1006]	-2	hSpCas9	negative selection	6299400
6391904	6391927	11	+	27260156	EWS502	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.31865992682973765	[982]	[1028,1184,1642,1379]	5	hSpCas9	negative selection	6363651
6393608	6393631	11	+	27260156	EWS502	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3806244700305818	[427]	[591,543,501,730]	6	hSpCas9	negative selection	6363652
6393679	6393702	11	-	27260156	EWS502	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.233948205793309	[808]	[854,902,1025,1285]	4	hSpCas9	negative selection	6363653
6393310	6393333	11	+	27260156	EW8	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.04567586086613615	[416]	[367,300,348,377]	0	hSpCas9	negative selection	6420649
6392142	6392165	11	-	27260156	EW8	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.592205100261515	[571]	[335,324,303,267]	-8	hSpCas9	negative selection	6420650
6394021	6394044	11	-	27260156	EW8	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.118214465498104	[893]	[893,677,509,637]	-2	hSpCas9	negative selection	6420651
6391904	6391927	11	+	27260156	EW8	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.22777442147665994	[982]	[1043,1190,772,761]	4	hSpCas9	negative selection	6484902
6393608	6393631	11	+	27260156	EW8	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.35997441873680924	[427]	[565,444,306,497]	6	hSpCas9	negative selection	6484903
6393679	6393702	11	-	27260156	EW8	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.0684676813918298	[808]	[696,888,468,731]	1	hSpCas9	negative selection	6484904
6393310	6393333	11	+	27260156	CORL105	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.1815624165332559	[416]	[499,437,702,596]	3	hSpCas9	negative selection	6541900
6392142	6392165	11	-	27260156	CORL105	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.14725943114640058	[571]	[746,477,486,694]	-3	hSpCas9	negative selection	6541901
6394021	6394044	11	-	27260156	CORL105	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.35256897928603725	[893]	[810,659,1034,808]	-6	hSpCas9	negative selection	6541902
6391904	6391927	11	+	27260156	CORL105	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.17628792387361014	[982]	[1247,1306,1288,1352]	3	hSpCas9	negative selection	6606153
6393608	6393631	11	+	27260156	CORL105	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.133451720352917	[427]	[547,562,580,510]	2	hSpCas9	negative selection	6606154
6393679	6393702	11	-	27260156	CORL105	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.14211628531880205	[808]	[696,867,1018,867]	-3	hSpCas9	negative selection	6606155
6393310	6393333	11	+	27260156	HS294T	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.6957223453521196	[416]	[267,227,167,403]	8	hSpCas9	negative selection	6663151
6392142	6392165	11	-	27260156	HS294T	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.3598370603264921	[571]	[146,216,161,161]	-5	hSpCas9	negative selection	6663152
6394021	6394044	11	-	27260156	HS294T	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.3247228232654311	[893]	[249,215,243,421]	-4	hSpCas9	negative selection	6663153
6391904	6391927	11	+	27260156	HS294T	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.18514299973691273	[982]	[436,379,415,507]	2	hSpCas9	negative selection	6727404
6393608	6393631	11	+	27260156	HS294T	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.6969281138795971	[427]	[202,276,215,404]	8	hSpCas9	negative selection	6727405
6393679	6393702	11	-	27260156	HS294T	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.09834978197030209	[808]	[259,305,348,450]	1	hSpCas9	negative selection	6727406
6393310	6393333	11	+	27260156	HCC44	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.3598644183680514	[416]	[675,619,674,465]	6	hSpCas9	negative selection	6784402
6392142	6392165	11	-	27260156	HCC44	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.25256333318275137	[571]	[704,255,694,591]	-4	hSpCas9	negative selection	6784403
6394021	6394044	11	-	27260156	HCC44	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.007977177485885445	[893]	[988,839,1176,1099]	0	hSpCas9	negative selection	6784404
6391904	6391927	11	+	27260156	HCC44	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.437142813723445	[982]	[1297,1422,1998,1370]	7	hSpCas9	negative selection	6848655
6393608	6393631	11	+	27260156	HCC44	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3432131657287307	[427]	[959,334,725,523]	5	hSpCas9	negative selection	6848656
6393679	6393702	11	-	27260156	HCC44	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.18898562317355094	[808]	[1190,800,1427,863]	3	hSpCas9	negative selection	6848657
6393310	6393333	11	+	27260156	G402	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.5061391190166895	[416]	[777,714,650,749]	6	hSpCas9	negative selection	6905653
6392142	6392165	11	-	27260156	G402	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	0.029172764820240338	[571]	[726,749,376,982]	0	hSpCas9	negative selection	6905654
6394021	6394044	11	-	27260156	G402	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.13925851157093005	[893]	[1089,821,1151,902]	-2	hSpCas9	negative selection	6905655
6391904	6391927	11	+	27260156	G402	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.39438218293077676	[982]	[1488,1844,1455,1515]	5	hSpCas9	negative selection	6969906
6393608	6393631	11	+	27260156	G402	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	1.0983802445241195	[427]	[1151,1389,719,1221]	9	hSpCas9	negative selection	6969907
6393679	6393702	11	-	27260156	G402	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.24501153653718166	[808]	[966,807,748,822]	-3	hSpCas9	negative selection	6969908
6393310	6393333	11	+	27260156	L33	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.4597175012110351	[416]	[684,188,324,626]	8	hSpCas9	negative selection	7026904
6392142	6392165	11	-	27260156	L33	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.28926108998092626	[571]	[538,191,247,467]	-6	hSpCas9	negative selection	7026905
6394021	6394044	11	-	27260156	L33	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.18270425017523495	[893]	[726,300,513,871]	-4	hSpCas9	negative selection	7026906
6391904	6391927	11	+	27260156	L33	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.17569793862947702	[982]	[1066,441,671,1225]	4	hSpCas9	negative selection	7091157
6393608	6393631	11	+	27260156	L33	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.22674130697026562	[427]	[523,204,299,500]	5	hSpCas9	negative selection	7091158
6393679	6393702	11	-	27260156	L33	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.13971124656899758	[808]	[711,278,470,794]	-3	hSpCas9	negative selection	7091159
6393310	6393333	11	+	27260156	K562	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.11602306289538017	[416]	[292,641,144,300]	-1	hSpCas9	negative selection	7148155
6392142	6392165	11	-	27260156	K562	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.6281171377634843	[571]	[264,308,279,438]	-6	hSpCas9	negative selection	7148156
6394021	6394044	11	-	27260156	K562	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.4010233335114326	[893]	[511,517,709,643]	-5	hSpCas9	negative selection	7148157
6391904	6391927	11	+	27260156	K562	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.20320059372443855	[982]	[1172,1161,884,834]	2	hSpCas9	negative selection	7212408
6393608	6393631	11	+	27260156	K562	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3881609335606921	[427]	[558,772,329,359]	5	hSpCas9	negative selection	7212409
6393679	6393702	11	-	27260156	K562	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.36607868823713996	[808]	[1005,689,942,1038]	4	hSpCas9	negative selection	7212410
6393310	6393333	11	+	27260156	HT29	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.14551656692873688	[416]	[591,517,436,675]	3	hSpCas9	negative selection	7269406
6392142	6392165	11	-	27260156	HT29	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.2361805473750041	[571]	[466,422,644,774]	-5	hSpCas9	negative selection	7269407
6394021	6394044	11	-	27260156	HT29	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.02260759555402081	[893]	[1170,1516,920,748]	0	hSpCas9	negative selection	7269408
6391904	6391927	11	+	27260156	HT29	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.23478037719365275	[982]	[1502,1558,1634,989]	4	hSpCas9	negative selection	7333659
6393608	6393631	11	+	27260156	HT29	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.5335931616950917	[427]	[788,791,749,689]	8	hSpCas9	negative selection	7333660
6393679	6393702	11	-	27260156	HT29	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.10984094057971028	[808]	[1304,1200,943,844]	2	hSpCas9	negative selection	7333661
6393310	6393333	11	+	27260156	MHHES1	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.3144291963587031	[416]	[697,697,652,353]	6	hSpCas9	negative selection	7390657
6392142	6392165	11	-	27260156	MHHES1	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.14810360104151038	[571]	[499,540,910,392]	-3	hSpCas9	negative selection	7390658
6394021	6394044	11	-	27260156	MHHES1	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.015032010957375164	[893]	[1016,984,1267,820]	0	hSpCas9	negative selection	7390659
6391904	6391927	11	+	27260156	MHHES1	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.024155127824275313	[982]	[1139,1371,1051,974]	0	hSpCas9	negative selection	7454910
6393608	6393631	11	+	27260156	MHHES1	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.46997909448207154	[427]	[725,748,554,644]	8	hSpCas9	negative selection	7454911
6393679	6393702	11	-	27260156	MHHES1	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.13728968744500514	[808]	[1182,1117,881,866]	2	hSpCas9	negative selection	7454912
6393310	6393333	11	+	27260156	MEWO	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.0650465516518933	[416]	[417,257,451]	-1	hSpCas9	negative selection	7511908
6392142	6392165	11	-	27260156	MEWO	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.42431558224660826	[571]	[556,380,288]	-7	hSpCas9	negative selection	7511909
6394021	6394044	11	-	27260156	MEWO	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.2007793172283755	[893]	[912,1017,942]	4	hSpCas9	negative selection	7511910
6391904	6391927	11	+	27260156	MEWO	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.12844434784703584	[982]	[1369,862,853]	3	hSpCas9	negative selection	7576161
6393608	6393631	11	+	27260156	MEWO	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.2242075708854892	[427]	[449,404,544]	5	hSpCas9	negative selection	7576162
6393679	6393702	11	-	27260156	MEWO	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.024866658338043468	[808]	[965,674,633]	0	hSpCas9	negative selection	7576163
6393310	6393333	11	+	27260156	LNCAPCLONEFGC	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.28667163323831746	[416]	[328,636,482,387]	4	hSpCas9	negative selection	7633159
6392142	6392165	11	-	27260156	LNCAPCLONEFGC	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.3108821822820642	[571]	[404,306,571,416]	-5	hSpCas9	negative selection	7633160
6394021	6394044	11	-	27260156	LNCAPCLONEFGC	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.3254901006075298	[893]	[651,527,744,681]	-5	hSpCas9	negative selection	7633161
6391904	6391927	11	+	27260156	LNCAPCLONEFGC	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.3229629117294488	[982]	[1170,913,1323,1088]	5	hSpCas9	negative selection	7697412
6393608	6393631	11	+	27260156	LNCAPCLONEFGC	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.6112390028545085	[427]	[530,669,560,597]	8	hSpCas9	negative selection	7697413
6393679	6393702	11	-	27260156	LNCAPCLONEFGC	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.03986283583241834	[808]	[582,702,937,822]	0	hSpCas9	negative selection	7697414
6393310	6393333	11	+	27260156	PANC0327	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.13587498788694458	[416]	[288,387,373,286]	-2	hSpCas9	negative selection	7754410
6392142	6392165	11	-	27260156	PANC0327	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.07364102288357574	[571]	[265,612,675,341]	-1	hSpCas9	negative selection	7754411
6394021	6394044	11	-	27260156	PANC0327	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.2757925933123887	[893]	[612,801,502,682]	-4	hSpCas9	negative selection	7754412
6391904	6391927	11	+	27260156	PANC0327	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.39944747113152634	[982]	[1489,780,1055,1354]	6	hSpCas9	negative selection	7818663
6393608	6393631	11	+	27260156	PANC0327	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.743390189886004	[427]	[711,371,660,840]	9	hSpCas9	negative selection	7818664
6393679	6393702	11	-	27260156	PANC0327	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.2766454403419175	[808]	[404,601,540,807]	-4	hSpCas9	negative selection	7818665
6393310	6393333	11	+	27260156	NCIH2009	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.28328377101226326	[416]	[706,678,739]	4	hSpCas9	negative selection	7875661
6392142	6392165	11	-	27260156	NCIH2009	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.1010217339975795	[571]	[1070,608,620]	-1	hSpCas9	negative selection	7875662
6394021	6394044	11	-	27260156	NCIH2009	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.3701402044672847	[893]	[1178,833,928]	-5	hSpCas9	negative selection	7875663
6391904	6391927	11	+	27260156	NCIH2009	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.2841218599972275	[982]	[2371,1424,1359]	4	hSpCas9	negative selection	7939914
6393608	6393631	11	+	27260156	NCIH2009	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.9693479716099422	[427]	[1101,998,1398]	9	hSpCas9	negative selection	7939915
6393679	6393702	11	-	27260156	NCIH2009	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.02276516029446063	[808]	[1270,904,1194]	0	hSpCas9	negative selection	7939916
6393310	6393333	11	+	27260156	NCIH1373	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.10563472222719683	[416]	[687,265,356,127]	-1	hSpCas9	negative selection	7996912
6392142	6392165	11	-	27260156	NCIH1373	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.025517802314631743	[571]	[533,623,503,224]	0	hSpCas9	negative selection	7996913
6394021	6394044	11	-	27260156	NCIH1373	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.4078207745973843	[893]	[806,407,1104,192]	-4	hSpCas9	negative selection	7996914
6391904	6391927	11	+	27260156	NCIH1373	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.3687671688138785	[982]	[1452,1321,1526,365]	3	hSpCas9	negative selection	8061165
6393608	6393631	11	+	27260156	NCIH1373	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.5504669645534737	[427]	[774,566,770,188]	5	hSpCas9	negative selection	8061166
6393679	6393702	11	-	27260156	NCIH1373	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.15734686437945422	[808]	[1459,610,977,291]	1	hSpCas9	negative selection	8061167
6393310	6393333	11	+	27260156	PATU8902	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.32569995909092536	[416]	[797,660,743,692]	3	hSpCas9	negative selection	8118163
6392142	6392165	11	-	27260156	PATU8902	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.08107677741215258	[571]	[762,1148,387,808]	-1	hSpCas9	negative selection	8118164
6394021	6394044	11	-	27260156	PATU8902	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.04610371019624604	[893]	[1591,1422,848,1389]	0	hSpCas9	negative selection	8118165
6391904	6391927	11	+	27260156	PATU8902	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.5783507650514512	[982]	[860,2125,2469,2684]	6	hSpCas9	negative selection	8182416
6393608	6393631	11	+	27260156	PATU8902	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.6603965986610247	[427]	[1010,1103,839,816]	7	hSpCas9	negative selection	8182417
6393679	6393702	11	-	27260156	PATU8902	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.35092719073017065	[808]	[991,1766,1390,1627]	3	hSpCas9	negative selection	8182418
6393310	6393333	11	+	27260156	PANC1	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.10501824326669718	[416]	[296,459,270,325]	-2	hSpCas9	negative selection	8239414
6392142	6392165	11	-	27260156	PANC1	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.42453913882529837	[571]	[376,526,406,206]	-6	hSpCas9	negative selection	8239415
6394021	6394044	11	-	27260156	PANC1	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.22196546652197924	[893]	[662,810,503,671]	-4	hSpCas9	negative selection	8239416
6391904	6391927	11	+	27260156	PANC1	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.2696491312981104	[982]	[964,1073,1123,920]	4	hSpCas9	negative selection	8303667
6393608	6393631	11	+	27260156	PANC1	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.6424027563127388	[427]	[580,636,526,555]	9	hSpCas9	negative selection	8303668
6393679	6393702	11	-	27260156	PANC1	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.07229343953999812	[808]	[576,962,876,571]	1	hSpCas9	negative selection	8303669
6393310	6393333	11	+	27260156	PANC0813	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.4014460416085335	[416]	[505,793,804,478]	6	hSpCas9	negative selection	8360665
6392142	6392165	11	-	27260156	PANC0813	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	0.199925915051603	[571]	[648,765,733,916]	3	hSpCas9	negative selection	8360666
6394021	6394044	11	-	27260156	PANC0813	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.1399795538709806	[893]	[1316,1211,1016,1097]	2	hSpCas9	negative selection	8360667
6391904	6391927	11	+	27260156	PANC0813	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.11080313628394367	[982]	[1464,1048,1182,1304]	1	hSpCas9	negative selection	8424918
6393608	6393631	11	+	27260156	PANC0813	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.7286052290255562	[427]	[981,735,955,679]	9	hSpCas9	negative selection	8424919
6393679	6393702	11	-	27260156	PANC0813	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.34527794218877156	[808]	[810,690,871,629]	-5	hSpCas9	negative selection	8424920
6393310	6393333	11	+	27260156	RDES	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.004536030291480586	[416]	[432,453,474,558]	0	hSpCas9	negative selection	8481916
6392142	6392165	11	-	27260156	RDES	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.5375106574916182	[571]	[374,436,439,584]	-7	hSpCas9	negative selection	8481917
6394021	6394044	11	-	27260156	RDES	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.5070417513455435	[893]	[595,691,806,825]	-7	hSpCas9	negative selection	8481918
6391904	6391927	11	+	27260156	RDES	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.272883697594934	[982]	[1201,1256,1400,1650]	4	hSpCas9	negative selection	8546169
6393608	6393631	11	+	27260156	RDES	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.5026053795308201	[427]	[631,677,584,916]	7	hSpCas9	negative selection	8546170
6393679	6393702	11	-	27260156	RDES	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.019063736759307837	[808]	[747,709,1141,1145]	0	hSpCas9	negative selection	8546171
6393310	6393333	11	+	27260156	PC3	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.25286871657072585	[416]	[396,392,804,495]	5	hSpCas9	negative selection	8603167
6392142	6392165	11	-	27260156	PC3	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.2356269865746107	[571]	[233,470,968,526]	-5	hSpCas9	negative selection	8603168
6394021	6394044	11	-	27260156	PC3	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.09552949595200089	[893]	[515,940,1268,830]	-2	hSpCas9	negative selection	8603169
6391904	6391927	11	+	27260156	PC3	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.07075049405839828	[982]	[737,943,1714,1004]	1	hSpCas9	negative selection	8667420
6393608	6393631	11	+	27260156	PC3	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.23566627923758116	[427]	[365,410,826,542]	5	hSpCas9	negative selection	8667421
6393679	6393702	11	-	27260156	PC3	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.10704551900119563	[808]	[450,932,1316,1062]	2	hSpCas9	negative selection	8667422
6393310	6393333	11	+	27260156	PATU8988T	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.45399429156362076	[416]	[373,851,567,431]	7	hSpCas9	negative selection	8724418
6392142	6392165	11	-	27260156	PATU8988T	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.15061199578095513	[571]	[509,581,407,500]	-3	hSpCas9	negative selection	8724419
6394021	6394044	11	-	27260156	PATU8988T	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.23511346242261533	[893]	[1145,1021,671,1250]	4	hSpCas9	negative selection	8724420
6391904	6391927	11	+	27260156	PATU8988T	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.06701701395217174	[982]	[1078,934,894,1072]	1	hSpCas9	negative selection	8788671
6393608	6393631	11	+	27260156	PATU8988T	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.39983241856410595	[427]	[591,582,535,468]	6	hSpCas9	negative selection	8788672
6393679	6393702	11	-	27260156	PATU8988T	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.4339971541830253	[808]	[956,1361,843,1095]	7	hSpCas9	negative selection	8788673
6393310	6393333	11	+	27260156	T47D	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.10129499493643936	[416]	[409,507,584,582]	2	hSpCas9	negative selection	8845669
6392142	6392165	11	-	27260156	T47D	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.1971007453624617	[571]	[691,562,519,551]	-4	hSpCas9	negative selection	8845670
6394021	6394044	11	-	27260156	T47D	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.1401858883505539	[893]	[1029,856,950,949]	-3	hSpCas9	negative selection	8845671
6391904	6391927	11	+	27260156	T47D	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.3046669893086409	[982]	[1368,1439,1443,1400]	6	hSpCas9	negative selection	8909922
6393608	6393631	11	+	27260156	T47D	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.3576994475491072	[427]	[594,546,719,701]	7	hSpCas9	negative selection	8909923
6393679	6393702	11	-	27260156	T47D	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.09350956453637116	[808]	[1068,999,900,1055]	2	hSpCas9	negative selection	8909924
6393310	6393333	11	+	27260156	SU8686	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.42687325735810716	[416]	[447,402,631,811]	7	hSpCas9	negative selection	8966920
6392142	6392165	11	-	27260156	SU8686	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.15699452779831283	[571]	[412,511,566,558]	-3	hSpCas9	negative selection	8966921
6394021	6394044	11	-	27260156	SU8686	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.0205742205313747	[893]	[627,915,1016,1091]	0	hSpCas9	negative selection	8966922
6391904	6391927	11	+	27260156	SU8686	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.18476970295788542	[982]	[997,791,1199,1562]	3	hSpCas9	negative selection	9031173
6393608	6393631	11	+	27260156	SU8686	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.46040114864975296	[427]	[505,499,771,576]	7	hSpCas9	negative selection	9031174
6393679	6393702	11	-	27260156	SU8686	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.04825127043951216	[808]	[630,821,910,1000]	0	hSpCas9	negative selection	9031175
6393310	6393333	11	+	27260156	SKES1	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.398567622154288	[416]	[575,607,429,581]	7	hSpCas9	negative selection	9088171
6392142	6392165	11	-	27260156	SKES1	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.3512355439926676	[571]	[339,565,440,437]	-6	hSpCas9	negative selection	9088172
6394021	6394044	11	-	27260156	SKES1	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.007701246672484396	[893]	[1007,1006,817,753]	0	hSpCas9	negative selection	9088173
6391904	6391927	11	+	27260156	SKES1	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.3945873989282329	[982]	[1335,1269,1375,1176]	7	hSpCas9	negative selection	9152424
6393608	6393631	11	+	27260156	SKES1	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.4994416654520419	[427]	[803,689,482,484]	8	hSpCas9	negative selection	9152425
6393679	6393702	11	-	27260156	SKES1	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.05606329099196439	[808]	[954,987,828,633]	1	hSpCas9	negative selection	9152426
6393310	6393333	11	+	27260156	TOV112D	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.05159123971013373	[416]	[642,425,436,245]	1	hSpCas9	negative selection	9209422
6392142	6392165	11	-	27260156	TOV112D	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.6556097799895291	[571]	[300,410,331,414]	-8	hSpCas9	negative selection	9209423
6394021	6394044	11	-	27260156	TOV112D	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.22798931162218805	[893]	[1009,702,610,738]	-4	hSpCas9	negative selection	9209424
6391904	6391927	11	+	27260156	TOV112D	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.1340765440730598	[982]	[983,1567,845,1034]	2	hSpCas9	negative selection	9273675
6393608	6393631	11	+	27260156	TOV112D	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.4435997997233645	[427]	[570,630,637,503]	7	hSpCas9	negative selection	9273676
6393679	6393702	11	-	27260156	TOV112D	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.008159370774543984	[808]	[797,728,945,730]	0	hSpCas9	negative selection	9273677
6393310	6393333	11	+	27260156	TC71	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	0.1007216837829362	[416]	[404,407,474,640]	2	hSpCas9	negative selection	9330673
6392142	6392165	11	-	27260156	TC71	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.5574976786839171	[571]	[431,388,335,517]	-9	hSpCas9	negative selection	9330674
6394021	6394044	11	-	27260156	TC71	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	0.07942391580503061	[893]	[1200,981,1034,814]	2	hSpCas9	negative selection	9330675
6391904	6391927	11	+	27260156	TC71	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.23510727811092358	[982]	[1267,1074,1131,1504]	6	hSpCas9	negative selection	9394926
6393608	6393631	11	+	27260156	TC71	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.4420053595471899	[427]	[542,612,571,777]	8	hSpCas9	negative selection	9394927
6393679	6393702	11	-	27260156	TC71	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	0.1089305058900063	[808]	[824,859,890,1183]	2	hSpCas9	negative selection	9394928
6393310	6393333	11	+	27260156	TC32	viability	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.05916455975445578	[416]	[332,279,458,471]	-1	hSpCas9	negative selection	9451924
6392142	6392165	11	-	27260156	TC32	viability	ATAAGTACCTGAGGGTGCGCAGG	SMPD1	ENSG00000166311	-0.2592935403326711	[571]	[475,347,519,472]	-5	hSpCas9	negative selection	9451925
6394021	6394044	11	-	27260156	TC32	viability	ACCAGGATTAAGGCCGATGTAGG	SMPD1	ENSG00000166311	-0.24077004665963564	[893]	[541,549,1028,825]	-4	hSpCas9	negative selection	9451926
6391904	6391927	11	+	27260156	TC32	viability	ACATCCCCGCACATGATGTCTGG	SMPD1	ENSG00000166311	0.1326161670853494	[982]	[1083,531,1401,1228]	2	hSpCas9	negative selection	9516177
6393608	6393631	11	+	27260156	TC32	viability	CCCTACTAGGTGCATATAATTGG	SMPD1	ENSG00000166311	0.8552574149540679	[427]	[609,746,792,731]	9	hSpCas9	negative selection	9516178
6393679	6393702	11	-	27260156	TC32	viability	CGTCCTACCTGGCTACAATTCGG	SMPD1	ENSG00000166311	-0.03124219517627036	[808]	[565,612,1031,848]	0	hSpCas9	negative selection	9516179
6390678	6390701	11	-	27869803	HPAFII	viability after 27 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.4378750160525797	[51]	[20,0,NaN]	-7	hSpCas9	negative selection	9542908
6390831	6390854	11	-	27869803	HPAFII	viability after 27 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.3621334471499875	[523]	[580,164,NaN]	3	hSpCas9	negative selection	9542909
6391737	6391760	11	+	27869803	HPAFII	viability after 27 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.7294141487191446	[50]	[92,3,NaN]	6	hSpCas9	negative selection	9542916
6393310	6393333	11	+	27869803	HPAFII	viability after 27 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.2501869395879588	[108]	[9,79,NaN]	-2	hSpCas9	negative selection	9542917
6394009	6394032	11	-	27869803	HPAFII	viability after 27 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.40159764282980004	[243]	[109,218,NaN]	3	hSpCas9	negative selection	9542918
6394369	6394392	11	-	27869803	HPAFII	viability after 27 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.22363658548319387	[88]	[28,75,NaN]	1	hSpCas9	negative selection	9542919
6390678	6390701	11	-	27869803	HPAFII	viability after 15 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.29544341131963225	[51]	[84,20,NaN]	-3	hSpCas9	negative selection	9625357
6390831	6390854	11	-	27869803	HPAFII	viability after 15 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.18062246956879102	[523]	[1006,408,NaN]	2	hSpCas9	negative selection	9625358
6391737	6391760	11	+	27869803	HPAFII	viability after 15 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.39122242018992526	[50]	[90,59,NaN]	4	hSpCas9	negative selection	9625365
6393310	6393333	11	+	27869803	HPAFII	viability after 15 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.6421169495746759	[108]	[42,94,NaN]	-6	hSpCas9	negative selection	9625366
6394009	6394032	11	-	27869803	HPAFII	viability after 15 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.04436205864643287	[243]	[183,297,NaN]	0	hSpCas9	negative selection	9625367
6394369	6394392	11	-	27869803	HPAFII	viability after 15 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.29917183665067526	[88]	[39,165,NaN]	3	hSpCas9	negative selection	9625368
6390678	6390701	11	-	27869803	ASPC1	viability after 36 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.16242415693013723	[169]	[149,11,16]	-2	hSpCas9	negative selection	9707806
6390831	6390854	11	-	27869803	ASPC1	viability after 36 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	-0.29526642307871864	[995]	[356,326,193]	-3	hSpCas9	negative selection	9707807
6391737	6391760	11	+	27869803	ASPC1	viability after 36 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	-1.198405282848387	[305]	[0,38,83]	-8	hSpCas9	negative selection	9707814
6393310	6393333	11	+	27869803	ASPC1	viability after 36 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.49956070163428734	[318]	[21,148,61]	-5	hSpCas9	negative selection	9707815
6394009	6394032	11	-	27869803	ASPC1	viability after 36 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.6844305246078617	[571]	[524,154,305]	6	hSpCas9	negative selection	9707816
6394369	6394392	11	-	27869803	ASPC1	viability after 36 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	1.159175223379052	[376]	[493,39,351]	9	hSpCas9	negative selection	9707817
6390678	6390701	11	-	27869803	PATU8988S	viability after 35 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.5723630468849996	[200]	[28,79,NaN]	-5	hSpCas9	negative selection	9790255
6390831	6390854	11	-	27869803	PATU8988S	viability after 35 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.014522106470218	[837]	[829,532,NaN]	9	hSpCas9	negative selection	9790256
6391737	6391760	11	+	27869803	PATU8988S	viability after 35 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.2458660114124649	[128]	[108,13,NaN]	3	hSpCas9	negative selection	9790263
6393310	6393333	11	+	27869803	PATU8988S	viability after 35 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-2.24697302351699	[270]	[19,25,NaN]	-9	hSpCas9	negative selection	9790264
6394009	6394032	11	-	27869803	PATU8988S	viability after 35 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.2279727167555097	[556]	[209,172,NaN]	-2	hSpCas9	negative selection	9790265
6394369	6394392	11	-	27869803	PATU8988S	viability after 35 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.27670659513410834	[200]	[127,67,NaN]	3	hSpCas9	negative selection	9790266
6390678	6390701	11	-	27869803	PATU8988S	viability after 31 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-0.7748762177968342	[200]	[52,38,NaN]	-7	hSpCas9	negative selection	9872704
6390831	6390854	11	-	27869803	PATU8988S	viability after 31 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.9760027362432436	[837]	[801,472,NaN]	9	hSpCas9	negative selection	9872705
6391737	6391760	11	+	27869803	PATU8988S	viability after 31 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	-0.5003682073800002	[128]	[49,18,NaN]	-5	hSpCas9	negative selection	9872712
6393310	6393333	11	+	27869803	PATU8988S	viability after 31 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-1.0453361427999106	[270]	[43,62,NaN]	-8	hSpCas9	negative selection	9872713
6394009	6394032	11	-	27869803	PATU8988S	viability after 31 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	-0.35973860056869966	[556]	[191,148,NaN]	-4	hSpCas9	negative selection	9872714
6394369	6394392	11	-	27869803	PATU8988S	viability after 31 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.3483859754592926	[200]	[94,110,NaN]	4	hSpCas9	negative selection	9872715
6390678	6390701	11	-	27869803	HPAFII	viability after 35 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-2.851157902192953	[51]	[5,0,NaN]	-8	hSpCas9	negative selection	9955153
6390831	6390854	11	-	27869803	HPAFII	viability after 35 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	1.1798203138968348	[523]	[901,261,NaN]	7	hSpCas9	negative selection	9955154
6391737	6391760	11	+	27869803	HPAFII	viability after 35 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	1.4683776630567118	[50]	[133,0,NaN]	8	hSpCas9	negative selection	9955161
6393310	6393333	11	+	27869803	HPAFII	viability after 35 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.8714329352234169	[108]	[0,62,NaN]	-5	hSpCas9	negative selection	9955162
6394009	6394032	11	-	27869803	HPAFII	viability after 35 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.3482946192837847	[243]	[73,250,NaN]	2	hSpCas9	negative selection	9955163
6394369	6394392	11	-	27869803	HPAFII	viability after 35 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	-0.34542454757776064	[88]	[18,53,NaN]	-2	hSpCas9	negative selection	9955164
6390678	6390701	11	-	27869803	HPAFII	viability after 31 days	GCCCATCCAAAGGAGTCCGGGGG	SMPD1	ENSG00000166311	-1.7260562089387608	[51]	[15,0,NaN]	-7	hSpCas9	negative selection	10037602
6390831	6390854	11	-	27869803	HPAFII	viability after 31 days	CCCAAAGACATCTCGGAGCCGGG	SMPD1	ENSG00000166311	0.6350511776287995	[523]	[717,171,NaN]	4	hSpCas9	negative selection	10037603
6391737	6391760	11	+	27869803	HPAFII	viability after 31 days	AGACCCACTGTGCTGCCGCCGGG	SMPD1	ENSG00000166311	0.2858056876145434	[50]	[65,0,NaN]	2	hSpCas9	negative selection	10037610
6393310	6393333	11	+	27869803	HPAFII	viability after 31 days	ATCAACTCCACGGATCCCGCAGG	SMPD1	ENSG00000166311	-0.8373829174276723	[108]	[5,64,NaN]	-5	hSpCas9	negative selection	10037611
6394009	6394032	11	-	27869803	HPAFII	viability after 31 days	GCCGATGTAGGTAGTTGCACTGG	SMPD1	ENSG00000166311	0.3189186888320115	[243]	[54,296,NaN]	2	hSpCas9	negative selection	10037612
6394369	6394392	11	-	27869803	HPAFII	viability after 31 days	ATATACCAGGTTGTGCCAGGCGG	SMPD1	ENSG00000166311	0.2888818188125364	[88]	[27,96,NaN]	2	hSpCas9	negative selection	10037613
6391387	6391410	11	+	28162770	P31FUJ	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.03237511457472216	[207]	[238]	0	hSpCas9	negative selection	10239414
6392122	6392145	11	-	28162770	P31FUJ	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7548140711297889	[116]	[231]	8	hSpCas9	negative selection	10239415
6391658	6391681	11	-	28162770	P31FUJ	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.9346545414371842	[64]	[145]	9	hSpCas9	negative selection	10239416
6391741	6391764	11	-	28162770	P31FUJ	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.6672050285601534	[49]	[36]	-5	hSpCas9	negative selection	10239417
6391871	6391894	11	-	28162770	P31FUJ	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-1.3259116088058596	[31]	[14]	-7	hSpCas9	negative selection	10239418
6391932	6391955	11	+	28162770	P31FUJ	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.15849557379519452	[336]	[441]	1	hSpCas9	negative selection	10239419
6392060	6392083	11	-	28162770	P31FUJ	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.39179172817553565	[689]	[617]	-4	hSpCas9	negative selection	10239420
6393246	6393269	11	-	28162770	P31FUJ	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.625119627193139	[188]	[71]	-7	hSpCas9	negative selection	10239421
6390688	6390711	11	-	28162770	P31FUJ	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.556553034232004	[264]	[457]	6	hSpCas9	negative selection	10239422
6391828	6391851	11	-	28162770	P31FUJ	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.6910517705145213	[304]	[221]	-5	hSpCas9	negative selection	10239423
6391387	6391410	11	+	28162770	TF1	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10408780
6392122	6392145	11	-	28162770	TF1	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10408781
6391658	6391681	11	-	28162770	TF1	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10408782
6391741	6391764	11	-	28162770	TF1	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10408783
6391871	6391894	11	-	28162770	TF1	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10408784
6391932	6391955	11	+	28162770	TF1	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10408785
6392060	6392083	11	-	28162770	TF1	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	NaN	[NaN]	[433]	1	hSpCas9	negative selection	10408786
6393246	6393269	11	-	28162770	TF1	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10408787
6390688	6390711	11	-	28162770	TF1	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10408788
6391828	6391851	11	-	28162770	TF1	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	NaN	[NaN]	[341]	1	hSpCas9	negative selection	10408789
6391387	6391410	11	+	28162770	SKM1	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.1578689838672417	[64]	[102]	-1	hSpCas9	negative selection	10578146
6392122	6392145	11	-	28162770	SKM1	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7352158122162465	[34]	[102]	7	hSpCas9	negative selection	10578147
6391658	6391681	11	-	28162770	SKM1	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	-0.8220016980220057	[18]	[18]	-6	hSpCas9	negative selection	10578148
6391741	6391764	11	-	28162770	SKM1	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.1699250014423126	[13]	[21]	-1	hSpCas9	negative selection	10578149
6391871	6391894	11	-	28162770	SKM1	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.2286243750479624	[13]	[28]	2	hSpCas9	negative selection	10578150
6391932	6391955	11	+	28162770	SKM1	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	-0.2537179384474797	[115]	[171]	-2	hSpCas9	negative selection	10578151
6392060	6392083	11	-	28162770	SKM1	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.6170199602343769	[130]	[150]	-5	hSpCas9	negative selection	10578152
6393246	6393269	11	-	28162770	SKM1	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.8220016980220054	[36]	[36]	-6	hSpCas9	negative selection	10578153
6390688	6390711	11	-	28162770	SKM1	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.3181759600262547	[48]	[107]	3	hSpCas9	negative selection	10578154
6391828	6391851	11	-	28162770	SKM1	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.5265458144958342	[65]	[80]	-4	hSpCas9	negative selection	10578155
6391387	6391410	11	+	28162770	SKM1	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.1578689838672417	[64]	[102]	-1	hSpCas9	negative selection	10747512
6392122	6392145	11	-	28162770	SKM1	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7352158122162465	[34]	[102]	7	hSpCas9	negative selection	10747513
6391658	6391681	11	-	28162770	SKM1	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	-0.8220016980220057	[18]	[18]	-6	hSpCas9	negative selection	10747514
6391741	6391764	11	-	28162770	SKM1	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.1699250014423126	[13]	[21]	-1	hSpCas9	negative selection	10747515
6391871	6391894	11	-	28162770	SKM1	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.2286243750479624	[13]	[28]	2	hSpCas9	negative selection	10747516
6391932	6391955	11	+	28162770	SKM1	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	-0.2537179384474797	[115]	[171]	-2	hSpCas9	negative selection	10747517
6392060	6392083	11	-	28162770	SKM1	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.6170199602343769	[130]	[150]	-5	hSpCas9	negative selection	10747518
6393246	6393269	11	-	28162770	SKM1	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.8220016980220054	[36]	[36]	-6	hSpCas9	negative selection	10747519
6390688	6390711	11	-	28162770	SKM1	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.3181759600262547	[48]	[107]	3	hSpCas9	negative selection	10747520
6391828	6391851	11	-	28162770	SKM1	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.5265458144958342	[65]	[80]	-4	hSpCas9	negative selection	10747521
6391387	6391410	11	+	28162770	PL21	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.3451899472926031	[207]	[114]	3	hSpCas9	negative selection	10916878
6392122	6392145	11	-	28162770	PL21	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7147127873190783	[69]	[49]	6	hSpCas9	negative selection	10916879
6391658	6391681	11	-	28162770	PL21	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.4879419254720563	[76]	[46]	4	hSpCas9	negative selection	10916880
6391741	6391764	11	-	28162770	PL21	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-1.214897884789524	[31]	[5]	-7	hSpCas9	negative selection	10916881
6391871	6391894	11	-	28162770	PL21	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-2.4437165752854044	[74]	[5]	-9	hSpCas9	negative selection	10916882
6391932	6391955	11	+	28162770	PL21	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	-0.3173392895158491	[354]	[123]	-2	hSpCas9	negative selection	10916883
6392060	6392083	11	-	28162770	PL21	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.6072153075682839	[433]	[123]	-4	hSpCas9	negative selection	10916884
6393246	6393269	11	-	28162770	PL21	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.975302391920558	[130]	[28]	-6	hSpCas9	negative selection	10916885
6390688	6390711	11	-	28162770	PL21	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	1.9748473026470774	[165]	[283]	9	hSpCas9	negative selection	10916886
6391828	6391851	11	-	28162770	PL21	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	1.0568825635090877	[200]	[181]	8	hSpCas9	negative selection	10916887
6391387	6391410	11	+	28162770	P31FUJ	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.03237511457472216	[207]	[238]	0	hSpCas9	negative selection	11086244
6392122	6392145	11	-	28162770	P31FUJ	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7548140711297889	[116]	[231]	8	hSpCas9	negative selection	11086245
6391658	6391681	11	-	28162770	P31FUJ	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.9346545414371842	[64]	[145]	9	hSpCas9	negative selection	11086246
6391741	6391764	11	-	28162770	P31FUJ	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.6672050285601534	[49]	[36]	-5	hSpCas9	negative selection	11086247
6391871	6391894	11	-	28162770	P31FUJ	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-1.3259116088058596	[31]	[14]	-7	hSpCas9	negative selection	11086248
6391932	6391955	11	+	28162770	P31FUJ	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.15849557379519452	[336]	[441]	1	hSpCas9	negative selection	11086249
6392060	6392083	11	-	28162770	P31FUJ	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.39179172817553565	[689]	[617]	-4	hSpCas9	negative selection	11086250
6393246	6393269	11	-	28162770	P31FUJ	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.625119627193139	[188]	[71]	-7	hSpCas9	negative selection	11086251
6390688	6390711	11	-	28162770	P31FUJ	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.556553034232004	[264]	[457]	6	hSpCas9	negative selection	11086252
6391828	6391851	11	-	28162770	P31FUJ	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.6910517705145213	[304]	[221]	-5	hSpCas9	negative selection	11086253
6391387	6391410	11	+	28162770	OCIAML5	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.5504799842316499	[86]	[229]	5	hSpCas9	negative selection	11255610
6392122	6392145	11	-	28162770	OCIAML5	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.0020825626725481383	[77]	[140]	0	hSpCas9	negative selection	11255611
6391658	6391681	11	-	28162770	OCIAML5	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	-0.6737293296054845	[37]	[42]	-4	hSpCas9	negative selection	11255612
6391741	6391764	11	-	28162770	OCIAML5	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-3.7589571664725154	[14]	[1]	-9	hSpCas9	negative selection	11255613
6391871	6391894	11	-	28162770	OCIAML5	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.2080544215735738	[46]	[97]	1	hSpCas9	negative selection	11255614
6391932	6391955	11	+	28162770	OCIAML5	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.42095192354241917	[119]	[289]	3	hSpCas9	negative selection	11255615
6392060	6392083	11	-	28162770	OCIAML5	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	0.21725448963990956	[385]	[809]	1	hSpCas9	negative selection	11255616
6393246	6393269	11	-	28162770	OCIAML5	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.1965121023127872	[112]	[88]	-6	hSpCas9	negative selection	11255617
6390688	6390711	11	-	28162770	OCIAML5	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.046053815116789534	[109]	[204]	0	hSpCas9	negative selection	11255618
6391828	6391851	11	-	28162770	OCIAML5	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.29188717107272893	[136]	[201]	-2	hSpCas9	negative selection	11255619
6391387	6391410	11	+	28162770	EOL1	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.35298620395837427	[319]	[131]	-3	hSpCas9	negative selection	11424976
6392122	6392145	11	-	28162770	EOL1	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	-0.35966065736766895	[150]	[61]	-3	hSpCas9	negative selection	11424977
6391658	6391681	11	-	28162770	EOL1	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	-0.6791512917322073	[154]	[50]	-5	hSpCas9	negative selection	11424978
6391741	6391764	11	-	28162770	EOL1	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.2222936167587366	[61]	[27]	-2	hSpCas9	negative selection	11424979
6391871	6391894	11	-	28162770	EOL1	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	0.8505471901267576	[79]	[75]	7	hSpCas9	negative selection	11424980
6391932	6391955	11	+	28162770	EOL1	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.20167700729011484	[712]	[431]	1	hSpCas9	negative selection	11424981
6392060	6392083	11	-	28162770	EOL1	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.04011915531718491	[604]	[309]	0	hSpCas9	negative selection	11424982
6393246	6393269	11	-	28162770	EOL1	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.1407436886811848	[225]	[53]	-6	hSpCas9	negative selection	11424983
6390688	6390711	11	-	28162770	EOL1	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.3460985778080528	[220]	[147]	3	hSpCas9	negative selection	11424984
6391828	6391851	11	-	28162770	EOL1	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.4330042330475492	[286]	[111]	-3	hSpCas9	negative selection	11424985
6391387	6391410	11	+	28162770	MOLM13	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.36529152788093044	[309]	[173]	-2	hSpCas9	negative selection	11594342
6392122	6392145	11	-	28162770	MOLM13	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.9454683468921352	[157]	[219]	7	hSpCas9	negative selection	11594343
6391658	6391681	11	-	28162770	MOLM13	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.6503674333299758	[88]	[100]	5	hSpCas9	negative selection	11594344
6391741	6391764	11	-	28162770	MOLM13	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.8216172356504061	[43]	[17]	-4	hSpCas9	negative selection	11594345
6391871	6391894	11	-	28162770	MOLM13	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.14354533053776874	[54]	[35]	-1	hSpCas9	negative selection	11594346
6391932	6391955	11	+	28162770	MOLM13	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	1.3923060297381111	[479]	[910]	9	hSpCas9	negative selection	11594347
6392060	6392083	11	-	28162770	MOLM13	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.9121416679063518	[759]	[291]	-5	hSpCas9	negative selection	11594348
6393246	6393269	11	-	28162770	MOLM13	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.5321106184554212	[203]	[50]	-6	hSpCas9	negative selection	11594349
6390688	6390711	11	-	28162770	MOLM13	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.14733094026925808	[264]	[172]	-1	hSpCas9	negative selection	11594350
6391828	6391851	11	-	28162770	MOLM13	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	0.6391608086944076	[237]	[267]	5	hSpCas9	negative selection	11594351
6391387	6391410	11	+	28162770	HEL	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.8112931017092547	[233]	[262]	7	hSpCas9	negative selection	11763708
6392122	6392145	11	-	28162770	HEL	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.7653581186643127	[123]	[134]	6	hSpCas9	negative selection	11763709
6391658	6391681	11	-	28162770	HEL	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.11480727631557985	[61]	[42]	0	hSpCas9	negative selection	11763710
6391741	6391764	11	-	28162770	HEL	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	0.7895802203296283	[55]	[61]	6	hSpCas9	negative selection	11763711
6391871	6391894	11	-	28162770	HEL	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-1.9422236687207994	[71]	[11]	-8	hSpCas9	negative selection	11763712
6391932	6391955	11	+	28162770	HEL	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	1.032255810598162	[441]	[578]	8	hSpCas9	negative selection	11763713
6392060	6392083	11	-	28162770	HEL	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.29446604126374676	[516]	[269]	-2	hSpCas9	negative selection	11763714
6393246	6393269	11	-	28162770	HEL	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-1.538326727047156	[194]	[42]	-7	hSpCas9	negative selection	11763715
6390688	6390711	11	-	28162770	HEL	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.07907453693330213	[220]	[133]	0	hSpCas9	negative selection	11763716
6391828	6391851	11	-	28162770	HEL	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.6150589254672899	[274]	[114]	-4	hSpCas9	negative selection	11763717
6391387	6391410	11	+	28162770	MV411	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	-0.27863126088481244	[215]	[149]	-2	hSpCas9	negative selection	11933074
6392122	6392145	11	-	28162770	MV411	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.5792811145352204	[115]	[145]	5	hSpCas9	negative selection	11933075
6391658	6391681	11	-	28162770	MV411	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.4049788277692553	[77]	[86]	3	hSpCas9	negative selection	11933076
6391741	6391764	11	-	28162770	MV411	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	0.5444192885399066	[34]	[42]	5	hSpCas9	negative selection	11933077
6391871	6391894	11	-	28162770	MV411	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.5046349357736393	[31]	[18]	-4	hSpCas9	negative selection	11933078
6391932	6391955	11	+	28162770	MV411	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	-0.24388987782715077	[342]	[243]	-2	hSpCas9	negative selection	11933079
6392060	6392083	11	-	28162770	MV411	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.13386909118351875	[464]	[356]	-1	hSpCas9	negative selection	11933080
6393246	6393269	11	-	28162770	MV411	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.8939182984627662	[149]	[67]	-6	hSpCas9	negative selection	11933081
6390688	6390711	11	-	28162770	MV411	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.10382403806275364	[235]	[184]	-1	hSpCas9	negative selection	11933082
6391828	6391851	11	-	28162770	MV411	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.3198229482049218	[242]	[163]	-2	hSpCas9	negative selection	11933083
6391387	6391410	11	+	28162770	MONOMAC1	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.46479441704587304	[133]	[211]	4	hSpCas9	negative selection	12102440
6392122	6392145	11	-	28162770	MONOMAC1	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.21800065221929021	[71]	[95]	2	hSpCas9	negative selection	12102441
6391658	6391681	11	-	28162770	MONOMAC1	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	-0.16141293732883244	[39]	[40]	-1	hSpCas9	negative selection	12102442
6391741	6391764	11	-	28162770	MONOMAC1	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-0.6120743463383973	[11]	[8]	-5	hSpCas9	negative selection	12102443
6391871	6391894	11	-	28162770	MONOMAC1	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	1.3575520046180836	[15]	[46]	9	hSpCas9	negative selection	12102444
6391932	6391955	11	+	28162770	MONOMAC1	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.6172708356398175	[206]	[363]	6	hSpCas9	negative selection	12102445
6392060	6392083	11	-	28162770	MONOMAC1	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.07618245218516817	[308]	[335]	0	hSpCas9	negative selection	12102446
6393246	6393269	11	-	28162770	MONOMAC1	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.33619959473117894	[86]	[78]	-3	hSpCas9	negative selection	12102447
6390688	6390711	11	-	28162770	MONOMAC1	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.7509724521600856	[137]	[93]	-6	hSpCas9	negative selection	12102448
6391828	6391851	11	-	28162770	MONOMAC1	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.18738667702583445	[148]	[149]	-2	hSpCas9	negative selection	12102449
6391387	6391410	11	+	28162770	OCIAML2	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.534824604849947	[32]	[264]	5	hSpCas9	negative selection	12271806
6392122	6392145	11	-	28162770	OCIAML2	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	0.239863557562854	[21]	[143]	2	hSpCas9	negative selection	12271807
6391658	6391681	11	-	28162770	OCIAML2	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.3504000337125195	[14]	[105]	3	hSpCas9	negative selection	12271808
6391741	6391764	11	-	28162770	OCIAML2	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	0.3367250968154427	[7]	[55]	3	hSpCas9	negative selection	12271809
6391871	6391894	11	-	28162770	OCIAML2	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.37547259220182094	[10]	[46]	-3	hSpCas9	negative selection	12271810
6391932	6391955	11	+	28162770	OCIAML2	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.8266744826763787	[64]	[638]	7	hSpCas9	negative selection	12271811
6392060	6392083	11	-	28162770	OCIAML2	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	0.1053995507089871	[80]	[482]	1	hSpCas9	negative selection	12271812
6393246	6393269	11	-	28162770	OCIAML2	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.03767041796605475	[14]	[80]	0	hSpCas9	negative selection	12271813
6390688	6390711	11	-	28162770	OCIAML2	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	-0.06853138167081557	[41]	[221]	0	hSpCas9	negative selection	12271814
6391828	6391851	11	-	28162770	OCIAML2	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	0.009060632378936007	[44]	[250]	0	hSpCas9	negative selection	12271815
6391387	6391410	11	+	28162770	OCIAML3	viability	GAACCCAATGTGGCTCGCGTGGG	SMPD1	ENSG00000166311	0.9173319972538133	[66]	[381]	7	hSpCas9	negative selection	12441172
6392122	6392145	11	-	28162770	OCIAML3	viability	AGGGCTTCGGCAGGCAGCCAGGG	SMPD1	ENSG00000166311	-0.20698451721491595	[38]	[101]	-2	hSpCas9	negative selection	12441173
6391658	6391681	11	-	28162770	OCIAML3	viability	GAAGAGGATGCGGCTGACAGGGG	SMPD1	ENSG00000166311	0.018969236566589665	[16]	[51]	0	hSpCas9	negative selection	12441174
6391741	6391764	11	-	28162770	OCIAML3	viability	GAACCCCGGCGGCAGCACAGTGG	SMPD1	ENSG00000166311	-3.2944473584652556	[12]	[3]	-9	hSpCas9	negative selection	12441175
6391871	6391894	11	-	28162770	OCIAML3	viability	GTACACCATATCAAAAGGGCCGG	SMPD1	ENSG00000166311	-0.39606826271225404	[16]	[38]	-3	hSpCas9	negative selection	12441176
6391932	6391955	11	+	28162770	OCIAML3	viability	GACTCGTCAGGACCAACTGCGGG	SMPD1	ENSG00000166311	0.15806484623225125	[94]	[319]	1	hSpCas9	negative selection	12441177
6392060	6392083	11	-	28162770	OCIAML3	viability	GGAGTGGTTGCCCTCAATGAAGG	SMPD1	ENSG00000166311	-0.25741149564796517	[136]	[345]	-2	hSpCas9	negative selection	12441178
6393246	6393269	11	-	28162770	OCIAML3	viability	GAGAGATGAGGCGGAGACCGGGG	SMPD1	ENSG00000166311	-0.09650798085334633	[33]	[95]	0	hSpCas9	negative selection	12441179
6390688	6390711	11	-	28162770	OCIAML3	viability	CCAGCACCAGGCCCATCCAAAGG	SMPD1	ENSG00000166311	0.4110633492232588	[70]	[284]	4	hSpCas9	negative selection	12441180
6391828	6391851	11	-	28162770	OCIAML3	viability	AGGCTCTCCAGGGTCCTCAGGGG	SMPD1	ENSG00000166311	-0.02696704760026936	[53]	[159]	0	hSpCas9	negative selection	12441181