Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6658
• Symbol: SOX3
• Description: SRY-box transcription factor 3

DataSource: http://genomecrispr.dkfz.de/#!/results/SOX3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
140504775	140504798	X	-	26472758	Jiyoye	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.0034531954548638	[126]	[191]	6	hSpCas9	negative selection	153817
140503766	140503789	X	-	26472758	Jiyoye	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-1.3127166993013915	[111]	[33]	-7	hSpCas9	negative selection	153818
140504999	140505022	X	+	26472758	Jiyoye	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	1.0209927448992147	[65]	[100]	6	hSpCas9	negative selection	153819
140504964	140504987	X	-	26472758	Jiyoye	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.36931857684697	[369]	[215]	-3	hSpCas9	negative selection	153820
140504848	140504871	X	+	26472758	Jiyoye	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.048721410593397	[149]	[233]	7	hSpCas9	negative selection	153821
140504821	140504844	X	+	26472758	Jiyoye	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.010753560394376638	[153]	[116]	0	hSpCas9	negative selection	153822
140504666	140504689	X	-	26472758	Jiyoye	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.1922866889103978	[99]	[32]	-7	hSpCas9	negative selection	153823
140504583	140504606	X	-	26472758	Jiyoye	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.1046126114854421	[73]	[59]	0	hSpCas9	negative selection	153824
140504487	140504510	X	-	26472758	Jiyoye	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.43978004693780115	[174]	[178]	3	hSpCas9	negative selection	153825
140503835	140503858	X	-	26472758	Jiyoye	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.10339463332877036	[157]	[127]	0	hSpCas9	negative selection	153826
140504775	140504798	X	-	26472758	KBM7	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.41815773376010346	[635,371]	[352,270]	4	hSpCas9	negative selection	344935
140503766	140503789	X	-	26472758	KBM7	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.3461680451078645	[436,428]	[234,281]	3	hSpCas9	negative selection	344936
140504999	140505022	X	+	26472758	KBM7	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.9598694695243764	[268,151]	[159,212]	9	hSpCas9	negative selection	344937
140504964	140504987	X	-	26472758	KBM7	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.155698271794932	[1127,874]	[532,508]	1	hSpCas9	negative selection	344938
140504848	140504871	X	+	26472758	KBM7	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.6166753794967677	[645,563]	[363,498]	6	hSpCas9	negative selection	344939
140504821	140504844	X	+	26472758	KBM7	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.24171970330344916	[455,192]	[252,102]	2	hSpCas9	negative selection	344940
140504666	140504689	X	-	26472758	KBM7	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	0.18425851805726867	[183,168]	[68,116]	1	hSpCas9	negative selection	344941
140504583	140504606	X	-	26472758	KBM7	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.5399271628373443	[239,248]	[115,214]	6	hSpCas9	negative selection	344942
140504487	140504510	X	-	26472758	KBM7	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.9027536696517134	[767,896]	[680,794]	8	hSpCas9	negative selection	344943
140503835	140503858	X	-	26472758	KBM7	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.6969993821801104	[609,477]	[495,335]	7	hSpCas9	negative selection	344944
140504775	140504798	X	-	26472758	Raji	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.9123675529684565	[260]	[113]	8	hSpCas9	negative selection	536053
140503766	140503789	X	-	26472758	Raji	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.9544316125350008	[168]	[75]	8	hSpCas9	negative selection	536054
140504999	140505022	X	+	26472758	Raji	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	1.877901689250832	[67]	[57]	9	hSpCas9	negative selection	536055
140504964	140504987	X	-	26472758	Raji	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.2319503712866786	[498]	[135]	2	hSpCas9	negative selection	536056
140504848	140504871	X	+	26472758	Raji	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.207785432331437	[221]	[118]	9	hSpCas9	negative selection	536057
140504821	140504844	X	+	26472758	Raji	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.19665087347068683	[187]	[49]	1	hSpCas9	negative selection	536058
140504666	140504689	X	-	26472758	Raji	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.9457278010859629	[82]	[4]	-8	hSpCas9	negative selection	536059
140504583	140504606	X	-	26472758	Raji	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.093577735848569	[104]	[51]	8	hSpCas9	negative selection	536060
140504487	140504510	X	-	26472758	Raji	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.4484204532086663	[359]	[113]	4	hSpCas9	negative selection	536061
140503835	140503858	X	-	26472758	Raji	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.3000286133159954	[377]	[107]	3	hSpCas9	negative selection	536062
140504775	140504798	X	-	26472758	K562	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.3122187128809066	[477]	[1001]	9	hSpCas9	negative selection	727171
140503766	140503789	X	-	26472758	K562	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.4916364280374659	[320]	[380]	4	hSpCas9	negative selection	727172
140504999	140505022	X	+	26472758	K562	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.6580629916454244	[258]	[344]	5	hSpCas9	negative selection	727173
140504964	140504987	X	-	26472758	K562	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.9572675314695915	[747]	[1225]	7	hSpCas9	negative selection	727174
140504848	140504871	X	+	26472758	K562	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.9874608043396539	[615]	[1030]	8	hSpCas9	negative selection	727175
140504821	140504844	X	+	26472758	K562	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.561670335344336	[308]	[384]	4	hSpCas9	negative selection	727176
140504666	140504689	X	-	26472758	K562	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-2.562936194391158	[132]	[18]	-8	hSpCas9	negative selection	727177
140504583	140504606	X	-	26472758	K562	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.436330542548133	[122]	[280]	9	hSpCas9	negative selection	727178
140504487	140504510	X	-	26472758	K562	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	1.1143581871020738	[637]	[1165]	8	hSpCas9	negative selection	727179
140503835	140503858	X	-	26472758	K562	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	1.134940250867954	[389]	[722]	8	hSpCas9	negative selection	727180
140504260	140504283	X	-	26627737	DLD1	viability	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.5684714906970832	[250]	[176,68,102]	6	hSpCas9	negative selection	844681
140504274	140504297	X	+	26627737	DLD1	viability	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.6677954605451548	[75]	[74,24,15]	6	hSpCas9	negative selection	844682
140504378	140504401	X	-	26627737	DLD1	viability	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-0.15979137815759903	[124]	[68,8,26]	-2	hSpCas9	negative selection	844683
140504714	140504737	X	-	26627737	DLD1	viability	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.010223810719951487	[225]	[122,39,51]	0	hSpCas9	negative selection	844684
140504845	140504868	X	+	26627737	DLD1	viability	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.48469389955630715	[370]	[101,52,304]	5	hSpCas9	negative selection	844685
140504990	140505013	X	+	26627737	DLD1	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.7233521799831678	[218]	[112,100,122]	7	hSpCas9	negative selection	844686
140504260	140504283	X	-	26627737	GBM cells	viability after 5 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	-0.006137721059051859	[146]	[53,102]	0	hSpCas9	negative selection	926996
140504274	140504297	X	+	26627737	GBM cells	viability after 5 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.6563435716116073	[20]	[37,32]	9	hSpCas9	negative selection	926997
140504378	140504401	X	-	26627737	GBM cells	viability after 5 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.03641739863562021	[29]	[25,6]	0	hSpCas9	negative selection	926998
140504714	140504737	X	-	26627737	GBM cells	viability after 5 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.2633253010945611	[86]	[29,81]	4	hSpCas9	negative selection	926999
140504845	140504868	X	+	26627737	GBM cells	viability after 5 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.07189867607705602	[156]	[73,102]	1	hSpCas9	negative selection	927000
140504990	140505013	X	+	26627737	GBM cells	viability after 5 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.17592122327208382	[136]	[82,82]	2	hSpCas9	negative selection	927001
140504260	140504283	X	-	26627737	GBM cells	viability after 13 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.07209374807486524	[146]	[122,51]	0	hSpCas9	negative selection	1009311
140504274	140504297	X	+	26627737	GBM cells	viability after 13 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.673494050689121	[20]	[37,34]	9	hSpCas9	negative selection	1009312
140504378	140504401	X	-	26627737	GBM cells	viability after 13 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.38908930478098647	[29]	[33,10]	5	hSpCas9	negative selection	1009313
140504714	140504737	X	-	26627737	GBM cells	viability after 13 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.3545118020864335	[86]	[77,45]	4	hSpCas9	negative selection	1009314
140504845	140504868	X	+	26627737	GBM cells	viability after 13 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.18059882921673032	[156]	[79,109]	2	hSpCas9	negative selection	1009315
140504990	140505013	X	+	26627737	GBM cells	viability after 13 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.5627279926706512	[136]	[111,107]	7	hSpCas9	negative selection	1009316
140504260	140504283	X	-	26627737	GBM cells	viability after 21 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	-0.9138247998284879	[146]	[44,39]	-7	hSpCas9	negative selection	1091626
140504274	140504297	X	+	26627737	GBM cells	viability after 21 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.9964149579875248	[20]	[44,45]	9	hSpCas9	negative selection	1091627
140504378	140504401	X	-	26627737	GBM cells	viability after 21 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.6369403389896027	[29]	[28,21]	6	hSpCas9	negative selection	1091628
140504714	140504737	X	-	26627737	GBM cells	viability after 21 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.4729137134976513	[86]	[74,56]	5	hSpCas9	negative selection	1091629
140504845	140504868	X	+	26627737	GBM cells	viability after 21 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.585988203646578	[156]	[138,117]	6	hSpCas9	negative selection	1091630
140504990	140505013	X	+	26627737	GBM cells	viability after 21 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.7879505071089457	[136]	[139,117]	7	hSpCas9	negative selection	1091631
140504260	140504283	X	-	26627737	RPE1	viability after 9 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	8.109487365312475	[1]	[106,257]	9	hSpCas9	negative selection	1173941
140504274	140504297	X	+	26627737	RPE1	viability after 9 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.7228931341781812	[106]	[86,140]	8	hSpCas9	negative selection	1173942
140504378	140504401	X	-	26627737	RPE1	viability after 9 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-2.2237571275392654	[463]	[17,47]	-9	hSpCas9	negative selection	1173943
140504714	140504737	X	-	26627737	RPE1	viability after 9 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.8904517087794146	[215]	[25,49]	-6	hSpCas9	negative selection	1173944
140504845	140504868	X	+	26627737	RPE1	viability after 9 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.8190974407678985	[608]	[369,292]	5	hSpCas9	negative selection	1173945
140504990	140505013	X	+	26627737	RPE1	viability after 9 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.79111554528384	[382]	[369,472]	8	hSpCas9	negative selection	1173946
140504260	140504283	X	-	26627737	RPE1	viability after 12 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	7.562462239234949	[1]	[120,80]	9	hSpCas9	negative selection	1256256
140504274	140504297	X	+	26627737	RPE1	viability after 12 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.0792872898581287	[106]	[34,87]	6	hSpCas9	negative selection	1256257
140504378	140504401	X	-	26627737	RPE1	viability after 12 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-1.5308197661869594	[463]	[81,1]	-8	hSpCas9	negative selection	1256258
140504714	140504737	X	-	26627737	RPE1	viability after 12 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.08568399294927187	[215]	[60,47]	0	hSpCas9	negative selection	1256259
140504845	140504868	X	+	26627737	RPE1	viability after 12 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.7157422052323963	[608]	[360,170]	4	hSpCas9	negative selection	1256260
140504990	140505013	X	+	26627737	RPE1	viability after 12 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.3066756014901344	[382]	[221,288]	7	hSpCas9	negative selection	1256261
140504260	140504283	X	-	26627737	RPE1	viability after 15 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	7.5259811596716695	[1]	[116,91]	9	hSpCas9	negative selection	1338571
140504274	140504297	X	+	26627737	RPE1	viability after 15 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.4233922195189588	[106]	[98,63]	7	hSpCas9	negative selection	1338572
140504378	140504401	X	-	26627737	RPE1	viability after 15 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-1.4837977390521928	[463]	[78,15]	-7	hSpCas9	negative selection	1338573
140504714	140504737	X	-	26627737	RPE1	viability after 15 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.4503702008862547	[215]	[55,109]	3	hSpCas9	negative selection	1338574
140504845	140504868	X	+	26627737	RPE1	viability after 15 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.9902379706130932	[608]	[385,299]	6	hSpCas9	negative selection	1338575
140504990	140505013	X	+	26627737	RPE1	viability after 15 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.5196913838819817	[382]	[245,372]	7	hSpCas9	negative selection	1338576
140504260	140504283	X	-	26627737	RPE1	viability after 18 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	7.921785820572513	[1]	[141,118]	9	hSpCas9	negative selection	1420886
140504274	140504297	X	+	26627737	RPE1	viability after 18 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.711709330987967	[106]	[96,91]	8	hSpCas9	negative selection	1420887
140504378	140504401	X	-	26627737	RPE1	viability after 18 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-0.9796818871903853	[463]	[77,47]	-6	hSpCas9	negative selection	1420888
140504714	140504737	X	-	26627737	RPE1	viability after 18 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.06582251709800868	[215]	[104,2]	0	hSpCas9	negative selection	1420889
140504845	140504868	X	+	26627737	RPE1	viability after 18 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.5775418956486376	[608]	[179,314]	3	hSpCas9	negative selection	1420890
140504990	140505013	X	+	26627737	RPE1	viability after 18 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.5827823416937514	[382]	[239,383]	8	hSpCas9	negative selection	1420891
140504260	140504283	X	-	26627737	HeLa	viability after 8 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.0026252098921773	[190]	[152,108,229]	7	hSpCas9	negative selection	1503201
140504274	140504297	X	+	26627737	HeLa	viability after 8 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.1532548343842963	[457]	[553,591,223]	8	hSpCas9	negative selection	1503202
140504378	140504401	X	-	26627737	HeLa	viability after 8 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	6.981150617781825	[0]	[70,20,74]	9	hSpCas9	negative selection	1503203
140504714	140504737	X	-	26627737	HeLa	viability after 8 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.8580112526871512	[216]	[75,54,31]	-7	hSpCas9	negative selection	1503204
140504845	140504868	X	+	26627737	HeLa	viability after 8 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.8361010861566699	[465]	[417,298,379]	7	hSpCas9	negative selection	1503205
140504990	140505013	X	+	26627737	HeLa	viability after 8 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.3447855957761077	[197]	[119,62,144]	3	hSpCas9	negative selection	1503206
140504260	140504283	X	-	26627737	HeLa	viability after 12 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.9140885291610071	[190]	[100,250,81]	7	hSpCas9	negative selection	1585516
140504274	140504297	X	+	26627737	HeLa	viability after 12 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.5643914299536772	[457]	[460,705,493]	9	hSpCas9	negative selection	1585517
140504378	140504401	X	-	26627737	HeLa	viability after 12 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	7.060485236605536	[0]	[6,55,100]	9	hSpCas9	negative selection	1585518
140504714	140504737	X	-	26627737	HeLa	viability after 12 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.6014132729964647	[216]	[268,60,89]	5	hSpCas9	negative selection	1585519
140504845	140504868	X	+	26627737	HeLa	viability after 12 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.44317155754441206	[465]	[348,129,322]	4	hSpCas9	negative selection	1585520
140504990	140505013	X	+	26627737	HeLa	viability after 12 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.3155467608620557	[197]	[2,116,69]	-3	hSpCas9	negative selection	1585521
140504260	140504283	X	-	26627737	HeLa	viability after 15 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.3233385168069918	[190]	[299,176,97]	8	hSpCas9	negative selection	1667831
140504274	140504297	X	+	26627737	HeLa	viability after 15 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.5332817911246752	[457]	[202,848,573]	8	hSpCas9	negative selection	1667832
140504378	140504401	X	-	26627737	HeLa	viability after 15 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	6.1388475048130235	[0]	[21,0,65]	9	hSpCas9	negative selection	1667833
140504714	140504737	X	-	26627737	HeLa	viability after 15 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-1.9893967759836007	[216]	[0,43,21]	-9	hSpCas9	negative selection	1667834
140504845	140504868	X	+	26627737	HeLa	viability after 15 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.9805990678559805	[465]	[532,249,334]	7	hSpCas9	negative selection	1667835
140504990	140505013	X	+	26627737	HeLa	viability after 15 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.5198857536937862	[197]	[26,61,81]	-4	hSpCas9	negative selection	1667836
140504260	140504283	X	-	26627737	HeLa	viability after 18 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.3759641967761203	[190]	[210,151,97]	8	hSpCas9	negative selection	1750146
140504274	140504297	X	+	26627737	HeLa	viability after 18 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.5412290359176275	[457]	[137,707,573]	8	hSpCas9	negative selection	1750147
140504378	140504401	X	-	26627737	HeLa	viability after 18 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	6.173999262949569	[0]	[15,0,65]	9	hSpCas9	negative selection	1750148
140504714	140504737	X	-	26627737	HeLa	viability after 18 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-2.0723258726059615	[216]	[0,32,21]	-9	hSpCas9	negative selection	1750149
140504845	140504868	X	+	26627737	HeLa	viability after 18 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.9650000203525463	[465]	[348,207,334]	7	hSpCas9	negative selection	1750150
140504990	140505013	X	+	26627737	HeLa	viability after 18 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.47809628142507843	[197]	[19,52,81]	-4	hSpCas9	negative selection	1750151
140504260	140504283	X	-	26627737	HCT116	viability after 6 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	2.5855803959599726	[455]	[1021,103]	9	hSpCas9	negative selection	1832461
140504274	140504297	X	+	26627737	HCT116	viability after 6 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	-1.7276406630074284	[507]	[7,32]	-7	hSpCas9	negative selection	1832462
140504378	140504401	X	-	26627737	HCT116	viability after 6 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-1.8179258352054881	[146]	[12,2]	-8	hSpCas9	negative selection	1832463
140504714	140504737	X	-	26627737	HCT116	viability after 6 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-1.4962079629085105	[529]	[15,36]	-7	hSpCas9	negative selection	1832464
140504845	140504868	X	+	26627737	HCT116	viability after 6 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	-0.48874157687892605	[240]	[26,26]	-3	hSpCas9	negative selection	1832465
140504990	140505013	X	+	26627737	HCT116	viability after 6 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.9748346809998008	[349]	[53,137]	5	hSpCas9	negative selection	1832466
140504260	140504283	X	-	26627737	HCT116	viability after 8 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.7119463063293905	[66]	[82,52,45]	6	hSpCas9	negative selection	1914776
140504274	140504297	X	+	26627737	HCT116	viability after 8 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.5330001404847193	[468]	[434,322,364]	5	hSpCas9	negative selection	1914777
140504378	140504401	X	-	26627737	HCT116	viability after 8 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.35010743562180435	[56]	[40,28,49]	4	hSpCas9	negative selection	1914778
140504714	140504737	X	-	26627737	HCT116	viability after 8 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.6199556063860217	[71]	[41,31,107]	6	hSpCas9	negative selection	1914779
140504845	140504868	X	+	26627737	HCT116	viability after 8 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	-0.2750026334528184	[295]	[99,187,115]	-3	hSpCas9	negative selection	1914780
140504990	140505013	X	+	26627737	HCT116	viability after 8 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	3.205065265150658	[12]	[100,47,49]	9	hSpCas9	negative selection	1914781
140504260	140504283	X	-	26627737	HCT116	viability after 9 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.0365837707750558	[455]	[84,379]	7	hSpCas9	negative selection	1997091
140504274	140504297	X	+	26627737	HCT116	viability after 9 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	-1.2872898108382793	[507]	[30,74]	-7	hSpCas9	negative selection	1997092
140504378	140504401	X	-	26627737	HCT116	viability after 9 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.7690769107424889	[146]	[24,99]	5	hSpCas9	negative selection	1997093
140504714	140504737	X	-	26627737	HCT116	viability after 9 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.6689792779751589	[529]	[45,122]	-5	hSpCas9	negative selection	1997094
140504845	140504868	X	+	26627737	HCT116	viability after 9 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.8485119829121689	[240]	[97,129]	6	hSpCas9	negative selection	1997095
140504990	140505013	X	+	26627737	HCT116	viability after 9 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.8141379276924001	[349]	[3,91]	-5	hSpCas9	negative selection	1997096
140504260	140504283	X	-	26627737	HCT116	viability after 12 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.1393271762580446	[66]	[97,40,90]	8	hSpCas9	negative selection	2079406
140504274	140504297	X	+	26627737	HCT116	viability after 12 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.7901854246402671	[468]	[396,498,386]	7	hSpCas9	negative selection	2079407
140504378	140504401	X	-	26627737	HCT116	viability after 12 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-0.7792215568094472	[56]	[1,28,22]	-7	hSpCas9	negative selection	2079408
140504714	140504737	X	-	26627737	HCT116	viability after 12 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.8064546898683351	[71]	[70,61,64]	7	hSpCas9	negative selection	2079409
140504845	140504868	X	+	26627737	HCT116	viability after 12 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.16313822408123063	[295]	[105,234,188]	1	hSpCas9	negative selection	2079410
140504990	140505013	X	+	26627737	HCT116	viability after 12 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	3.573899985925086	[12]	[96,93,51]	9	hSpCas9	negative selection	2079411
140504260	140504283	X	-	26627737	HCT116	viability after 15 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.0086638461235053	[66]	[91,61,79]	8	hSpCas9	negative selection	2161721
140504274	140504297	X	+	26627737	HCT116	viability after 15 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.591621966389229	[468]	[352,516,341]	5	hSpCas9	negative selection	2161722
140504378	140504401	X	-	26627737	HCT116	viability after 15 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.5574559163238646	[56]	[21,42,75]	5	hSpCas9	negative selection	2161723
140504714	140504737	X	-	26627737	HCT116	viability after 15 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.5407220340794621	[71]	[46,0,129]	5	hSpCas9	negative selection	2161724
140504845	140504868	X	+	26627737	HCT116	viability after 15 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	-0.3075724741772111	[295]	[167,127,119]	-3	hSpCas9	negative selection	2161725
140504990	140505013	X	+	26627737	HCT116	viability after 15 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	3.300354334920427	[12]	[44,83,87]	9	hSpCas9	negative selection	2161726
140504260	140504283	X	-	26627737	HCT116	viability after 18 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.5271986826827284	[66]	[36,159,77]	9	hSpCas9	negative selection	2244036
140504274	140504297	X	+	26627737	HCT116	viability after 18 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.8124001973055872	[468]	[307,379,512]	6	hSpCas9	negative selection	2244037
140504378	140504401	X	-	26627737	HCT116	viability after 18 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.7749718929267428	[56]	[21,69,47]	6	hSpCas9	negative selection	2244038
140504714	140504737	X	-	26627737	HCT116	viability after 18 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.34436842337691687	[71]	[31,1,50]	-3	hSpCas9	negative selection	2244039
140504845	140504868	X	+	26627737	HCT116	viability after 18 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	-0.053136103837046755	[295]	[159,126,126]	0	hSpCas9	negative selection	2244040
140504990	140505013	X	+	26627737	HCT116	viability after 18 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	3.3292265047454013	[12]	[72,71,42]	9	hSpCas9	negative selection	2244041
140504921	140504944	X	+	24336569	HL60	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	-0.19694131804883208	[259]	[479]	-2	hSpCas9	negative selection	2296651
140504945	140504968	X	+	24336569	HL60	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.8722113926475343	[582]	[673]	-7	hSpCas9	negative selection	2296652
140504953	140504976	X	+	24336569	HL60	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	1.2735358158641148	[137]	[705]	8	hSpCas9	negative selection	2296653
140504958	140504981	X	+	24336569	HL60	viability	GCGAGTCCGGCGGGAAGGGTAGG	SOX3	ENSG00000134595	-0.19631290433585402	[1051]	[1942]	-2	hSpCas9	negative selection	2296654
140504964	140504987	X	-	24336569	HL60	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.35423286921604036	[623]	[1687]	3	hSpCas9	negative selection	2296655
140504990	140505013	X	+	24336569	HL60	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.28375494904951726	[1450]	[3737]	2	hSpCas9	negative selection	2296656
140504995	140505018	X	-	24336569	HL60	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	2.420466567616127	[148]	[1687]	9	hSpCas9	negative selection	2296657
140505000	140505023	X	-	24336569	HL60	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	1.0686394599006723	[113]	[505]	7	hSpCas9	negative selection	2296658
140505015	140505038	X	-	24336569	HL60	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	-1.5934471559929468	[317]	[222]	-8	hSpCas9	negative selection	2296659
140505032	140505055	X	+	24336569	HL60	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	0.5273451420466277	[119]	[365]	5	hSpCas9	negative selection	2296660
140504921	140504944	X	+	24336569	KBM7	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	0.8961899468780619	[117]	[598]	7	hSpCas9	negative selection	2363828
140504945	140504968	X	+	24336569	KBM7	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.3824561790159959	[378]	[792]	-3	hSpCas9	negative selection	2363829
140504953	140504976	X	+	24336569	KBM7	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	0.8876792287509634	[236]	[1195]	7	hSpCas9	negative selection	2363830
140504958	140504981	X	+	24336569	KBM7	viability	GCGAGTCCGGCGGGAAGGGTAGG	SOX3	ENSG00000134595	0.8188220603833101	[534]	[2573]	7	hSpCas9	negative selection	2363831
140504964	140504987	X	-	24336569	KBM7	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.4724131555594675	[379]	[1437]	4	hSpCas9	negative selection	2363832
140504990	140505013	X	+	24336569	KBM7	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.40395181532867297	[973]	[3514]	4	hSpCas9	negative selection	2363833
140504995	140505018	X	-	24336569	KBM7	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	-0.30483902443280053	[124]	[275]	-3	hSpCas9	negative selection	2363834
140505000	140505023	X	-	24336569	KBM7	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	1.5017947303811496	[28]	[223]	9	hSpCas9	negative selection	2363835
140505015	140505038	X	-	24336569	KBM7	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	1.015667395772581	[102]	[567]	8	hSpCas9	negative selection	2363836
140505032	140505055	X	+	24336569	KBM7	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	-1.182931939746788	[148]	[178]	-7	hSpCas9	negative selection	2363837
140505153	140505176	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGCGAACCTGTCAATCACGGG	SOX3	ENSG00000134595	1.575406074276225	[92,25]	[11,66]	6	dCas9-VP64	positive selection	2438377
140505182	140505205	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTCGGTAATGATTGGCCAGGG	SOX3	ENSG00000134595	2.024985297198577	[3,13]	[12,2]	7	dCas9-VP64	positive selection	2438378
140505203	140505226	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCCAGCCAGGCCGAACGGGGG	SOX3	ENSG00000134595	-1.845146863613955	[123,11]	[5,1]	-8	dCas9-VP64	positive selection	2438379
140505153	140505176	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGCGAACCTGTCAATCACGGG	SOX3	ENSG00000134595	1.8870304821237813	[79,104]	[136,88]	8	dCas9-VP64	positive selection	2533632
140505182	140505205	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTCGGTAATGATTGGCCAGGG	SOX3	ENSG00000134595	0.5357410797543087	[36,19]	[16,9]	4	dCas9-VP64	positive selection	2533633
140505203	140505226	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCCAGCCAGGCCGAACGGGGG	SOX3	ENSG00000134595	0.24481639690658274	[106,26]	[39,12]	2	dCas9-VP64	positive selection	2533634
140504990	140505013	X	+	27260157	DLD1	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.746142316667208	[]	[]	8	hSpCas9	negative selection	2576131
140504921	140504944	X	+	27260157	DLD1	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	0.520377067001852	[]	[]	8	hSpCas9	negative selection	2578299
140504953	140504976	X	+	27260157	DLD1	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	0.859703605156482	[]	[]	9	hSpCas9	negative selection	2579619
140505000	140505023	X	-	27260157	DLD1	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	0.127011745079639	[]	[]	3	hSpCas9	negative selection	2582137
140504464	140504487	X	+	27260157	DLD1	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.264068836229436	[]	[]	-2	hSpCas9	negative selection	2586189
140504775	140504798	X	-	27260157	DLD1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.06692426924287	[]	[]	9	hSpCas9	negative selection	2586435
140504779	140504802	X	+	27260157	DLD1	viability	CGCTTGTGTGGGTGTCCCTACGG	SOX3	ENSG00000134595	-0.481261390451758	[]	[]	-4	hSpCas9	negative selection	2605249
140505015	140505038	X	-	27260157	DLD1	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	0.869203026036001	[]	[]	9	hSpCas9	negative selection	2608008
140504859	140504882	X	-	27260157	DLD1	viability	GCCTTCTCCTCCCGCCACGCTGG	SOX3	ENSG00000134595	0.382144998808526	[]	[]	4	hSpCas9	negative selection	2610291
140505032	140505055	X	+	27260157	DLD1	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	-0.204377175366008	[]	[]	-1	hSpCas9	negative selection	2611704
140504995	140505018	X	-	27260157	DLD1	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.772291352990534	[]	[]	8	hSpCas9	negative selection	2613926
140504820	140504843	X	-	27260157	DLD1	viability	CCCGGCAATGTACAGCCTTCTGG	SOX3	ENSG00000134595	0.119361285278489	[]	[]	3	hSpCas9	negative selection	2619619
140504945	140504968	X	+	27260157	DLD1	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.640288327511928	[]	[]	-5	hSpCas9	negative selection	2642530
140504915	140504938	X	-	27260157	DLD1	viability	TCCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.236136583738353	[]	[]	4	hSpCas9	negative selection	2643971
140504892	140504915	X	+	27260157	DLD1	viability	CTGGAGCGGCCACGGTGAAAAGG	SOX3	ENSG00000134595	0.221398973493032	[]	[]	3	hSpCas9	negative selection	2644736
140504914	140504937	X	+	27260157	DLD1	viability	GCCCTGGGACTCCGTCGGAGCGG	SOX3	ENSG00000134595	0.609993349967673	[]	[]	8	hSpCas9	negative selection	2647811
140504638	140504661	X	-	27260157	DLD1	viability	CAGACCAGGACCGTGTGAAACGG	SOX3	ENSG00000134595	0.473598227801298	[]	[]	8	hSpCas9	negative selection	2648961
140504964	140504987	X	-	27260157	DLD1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.771183506601725	[]	[]	-6	hSpCas9	negative selection	2649276
140504990	140505013	X	+	27260157	HT1080	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.879642121920257	[]	[]	7	hSpCas9	negative selection	2652261
140504921	140504944	X	+	27260157	HT1080	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	0.746699913129864	[]	[]	6	hSpCas9	negative selection	2654429
140504953	140504976	X	+	27260157	HT1080	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	0.647775199392531	[]	[]	5	hSpCas9	negative selection	2655749
140505000	140505023	X	-	27260157	HT1080	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	0.533854071091812	[]	[]	5	hSpCas9	negative selection	2658267
140504464	140504487	X	+	27260157	HT1080	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.963536115255739	[]	[]	7	hSpCas9	negative selection	2662319
140504775	140504798	X	-	27260157	HT1080	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.72206963777082	[]	[]	6	hSpCas9	negative selection	2662565
140504779	140504802	X	+	27260157	HT1080	viability	CGCTTGTGTGGGTGTCCCTACGG	SOX3	ENSG00000134595	0.330275110949253	[]	[]	3	hSpCas9	negative selection	2681379
140505015	140505038	X	-	27260157	HT1080	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	0.0935651996405026	[]	[]	1	hSpCas9	negative selection	2684138
140504859	140504882	X	-	27260157	HT1080	viability	GCCTTCTCCTCCCGCCACGCTGG	SOX3	ENSG00000134595	1.08860705856857	[]	[]	8	hSpCas9	negative selection	2686421
140505032	140505055	X	+	27260157	HT1080	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	0.17415982256468	[]	[]	1	hSpCas9	negative selection	2687834
140504995	140505018	X	-	27260157	HT1080	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.698903195202825	[]	[]	6	hSpCas9	negative selection	2690056
140504820	140504843	X	-	27260157	HT1080	viability	CCCGGCAATGTACAGCCTTCTGG	SOX3	ENSG00000134595	0.0997423775992088	[]	[]	1	hSpCas9	negative selection	2695749
140504945	140504968	X	+	27260157	HT1080	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-1.16685992884285	[]	[]	-8	hSpCas9	negative selection	2718660
140504915	140504938	X	-	27260157	HT1080	viability	TCCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.340021537633647	[]	[]	3	hSpCas9	negative selection	2720101
140504892	140504915	X	+	27260157	HT1080	viability	CTGGAGCGGCCACGGTGAAAAGG	SOX3	ENSG00000134595	0.236434364457958	[]	[]	2	hSpCas9	negative selection	2720866
140504914	140504937	X	+	27260157	HT1080	viability	GCCCTGGGACTCCGTCGGAGCGG	SOX3	ENSG00000134595	1.06103151185415	[]	[]	8	hSpCas9	negative selection	2723941
140504638	140504661	X	-	27260157	HT1080	viability	CAGACCAGGACCGTGTGAAACGG	SOX3	ENSG00000134595	1.20472539160481	[]	[]	8	hSpCas9	negative selection	2725091
140504964	140504987	X	-	27260157	HT1080	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	1.05857437211956	[]	[]	8	hSpCas9	negative selection	2725406
140504990	140505013	X	+	27260157	MKN45	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.654117744696825	[]	[]	7	hSpCas9	negative selection	2728391
140504921	140504944	X	+	27260157	MKN45	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	1.51902837418885	[]	[]	9	hSpCas9	negative selection	2730559
140504953	140504976	X	+	27260157	MKN45	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	0.357718117366173	[]	[]	6	hSpCas9	negative selection	2731879
140505000	140505023	X	-	27260157	MKN45	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	1.31188559220464	[]	[]	9	hSpCas9	negative selection	2734397
140504464	140504487	X	+	27260157	MKN45	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.408238800778875	[]	[]	6	hSpCas9	negative selection	2738449
140504775	140504798	X	-	27260157	MKN45	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.27443118239855	[]	[]	9	hSpCas9	negative selection	2738695
140504779	140504802	X	+	27260157	MKN45	viability	CGCTTGTGTGGGTGTCCCTACGG	SOX3	ENSG00000134595	-0.110880723888351	[]	[]	0	hSpCas9	negative selection	2757509
140505015	140505038	X	-	27260157	MKN45	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	-0.67984113400033	[]	[]	-7	hSpCas9	negative selection	2760268
140504859	140504882	X	-	27260157	MKN45	viability	GCCTTCTCCTCCCGCCACGCTGG	SOX3	ENSG00000134595	0.613808625755219	[]	[]	7	hSpCas9	negative selection	2762551
140505032	140505055	X	+	27260157	MKN45	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	0.481776466279213	[]	[]	6	hSpCas9	negative selection	2763964
140504995	140505018	X	-	27260157	MKN45	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	1.91395972726021	[]	[]	9	hSpCas9	negative selection	2766186
140504820	140504843	X	-	27260157	MKN45	viability	CCCGGCAATGTACAGCCTTCTGG	SOX3	ENSG00000134595	0.981237536661165	[]	[]	8	hSpCas9	negative selection	2771879
140504945	140504968	X	+	27260157	MKN45	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.000733891299861893	[]	[]	0	hSpCas9	negative selection	2794790
140504915	140504938	X	-	27260157	MKN45	viability	TCCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.25589379400465	[]	[]	5	hSpCas9	negative selection	2796231
140504892	140504915	X	+	27260157	MKN45	viability	CTGGAGCGGCCACGGTGAAAAGG	SOX3	ENSG00000134595	-0.0109680344210428	[]	[]	0	hSpCas9	negative selection	2796996
140504914	140504937	X	+	27260157	MKN45	viability	GCCCTGGGACTCCGTCGGAGCGG	SOX3	ENSG00000134595	1.53081910768197	[]	[]	9	hSpCas9	negative selection	2800071
140504638	140504661	X	-	27260157	MKN45	viability	CAGACCAGGACCGTGTGAAACGG	SOX3	ENSG00000134595	0.702877464439283	[]	[]	7	hSpCas9	negative selection	2801221
140504964	140504987	X	-	27260157	MKN45	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.239323541894051	[]	[]	-1	hSpCas9	negative selection	2801536
140504990	140505013	X	+	27260157	RKO	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.942975768813178	[]	[]	8	hSpCas9	negative selection	2804521
140504921	140504944	X	+	27260157	RKO	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	0.668459803345908	[]	[]	7	hSpCas9	negative selection	2806689
140504953	140504976	X	+	27260157	RKO	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	-0.242912192528209	[]	[]	-1	hSpCas9	negative selection	2808009
140505000	140505023	X	-	27260157	RKO	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	0.652544425748598	[]	[]	3	hSpCas9	negative selection	2810527
140504464	140504487	X	+	27260157	RKO	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.788130769476957	[]	[]	8	hSpCas9	negative selection	2814579
140504775	140504798	X	-	27260157	RKO	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.02006690948463	[]	[]	9	hSpCas9	negative selection	2814825
140504779	140504802	X	+	27260157	RKO	viability	CGCTTGTGTGGGTGTCCCTACGG	SOX3	ENSG00000134595	-0.115830409230925	[]	[]	0	hSpCas9	negative selection	2833639
140505015	140505038	X	-	27260157	RKO	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	-0.375979030076901	[]	[]	-6	hSpCas9	negative selection	2836398
140504859	140504882	X	-	27260157	RKO	viability	GCCTTCTCCTCCCGCCACGCTGG	SOX3	ENSG00000134595	-0.308725027721112	[]	[]	-6	hSpCas9	negative selection	2838681
140505032	140505055	X	+	27260157	RKO	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	-0.0510540056092502	[]	[]	0	hSpCas9	negative selection	2840094
140504995	140505018	X	-	27260157	RKO	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	-0.293533697930435	[]	[]	-6	hSpCas9	negative selection	2842316
140504820	140504843	X	-	27260157	RKO	viability	CCCGGCAATGTACAGCCTTCTGG	SOX3	ENSG00000134595	0.854436333267493	[]	[]	8	hSpCas9	negative selection	2848009
140504945	140504968	X	+	27260157	RKO	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.995323971389209	[]	[]	-8	hSpCas9	negative selection	2870920
140504915	140504938	X	-	27260157	RKO	viability	TCCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.469295547546143	[]	[]	2	hSpCas9	negative selection	2872361
140504892	140504915	X	+	27260157	RKO	viability	CTGGAGCGGCCACGGTGAAAAGG	SOX3	ENSG00000134595	0.469780674765196	[]	[]	2	hSpCas9	negative selection	2873126
140504914	140504937	X	+	27260157	RKO	viability	GCCCTGGGACTCCGTCGGAGCGG	SOX3	ENSG00000134595	0.88480211246372	[]	[]	8	hSpCas9	negative selection	2876201
140504638	140504661	X	-	27260157	RKO	viability	CAGACCAGGACCGTGTGAAACGG	SOX3	ENSG00000134595	1.07181324908093	[]	[]	9	hSpCas9	negative selection	2877351
140504964	140504987	X	-	27260157	RKO	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.217042911832273	[]	[]	1	hSpCas9	negative selection	2877666
140504990	140505013	X	+	27260157	SF268	viability	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.37827877351868	[]	[]	4	hSpCas9	negative selection	2880651
140504921	140504944	X	+	27260157	SF268	viability	GACTCCGTCGGAGCGGAGCTTGG	SOX3	ENSG00000134595	0.999675177013732	[]	[]	9	hSpCas9	negative selection	2882819
140504953	140504976	X	+	27260157	SF268	viability	GGCCAGCGAGTCCGGCGGGAAGG	SOX3	ENSG00000134595	-0.649457289900895	[]	[]	-5	hSpCas9	negative selection	2884139
140505000	140505023	X	-	27260157	SF268	viability	CCCGCGGGTTCCTGCTGATTTGG	SOX3	ENSG00000134595	0.681485744351223	[]	[]	8	hSpCas9	negative selection	2886657
140504464	140504487	X	+	27260157	SF268	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.076346143282583	[]	[]	0	hSpCas9	negative selection	2890709
140504775	140504798	X	-	27260157	SF268	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.752681665301752	[]	[]	8	hSpCas9	negative selection	2890955
140504779	140504802	X	+	27260157	SF268	viability	CGCTTGTGTGGGTGTCCCTACGG	SOX3	ENSG00000134595	-0.61276584718907	[]	[]	-5	hSpCas9	negative selection	2909769
140505015	140505038	X	-	27260157	SF268	viability	ATCAGGTGCGAGAAGCCCGCGGG	SOX3	ENSG00000134595	0.3289628537254	[]	[]	4	hSpCas9	negative selection	2912528
140504859	140504882	X	-	27260157	SF268	viability	GCCTTCTCCTCCCGCCACGCTGG	SOX3	ENSG00000134595	0.382300666927756	[]	[]	4	hSpCas9	negative selection	2914811
140505032	140505055	X	+	27260157	SF268	viability	CCTGATGAGTTCTCTCGAACAGG	SOX3	ENSG00000134595	0.461585321446753	[]	[]	7	hSpCas9	negative selection	2916224
140504995	140505018	X	-	27260157	SF268	viability	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.411162066739295	[]	[]	4	hSpCas9	negative selection	2918446
140504820	140504843	X	-	27260157	SF268	viability	CCCGGCAATGTACAGCCTTCTGG	SOX3	ENSG00000134595	1.23848887068042	[]	[]	9	hSpCas9	negative selection	2924139
140504945	140504968	X	+	27260157	SF268	viability	GGCCTGTGGGCCAGCGAGTCCGG	SOX3	ENSG00000134595	-0.709043467182068	[]	[]	-5	hSpCas9	negative selection	2947050
140504915	140504938	X	-	27260157	SF268	viability	TCCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.708074502940654	[]	[]	8	hSpCas9	negative selection	2948491
140504892	140504915	X	+	27260157	SF268	viability	CTGGAGCGGCCACGGTGAAAAGG	SOX3	ENSG00000134595	1.00665247253359	[]	[]	9	hSpCas9	negative selection	2949256
140504914	140504937	X	+	27260157	SF268	viability	GCCCTGGGACTCCGTCGGAGCGG	SOX3	ENSG00000134595	1.25245675820816	[]	[]	9	hSpCas9	negative selection	2952331
140504638	140504661	X	-	27260157	SF268	viability	CAGACCAGGACCGTGTGAAACGG	SOX3	ENSG00000134595	0.801947253961992	[]	[]	8	hSpCas9	negative selection	2953481
140504964	140504987	X	-	27260157	SF268	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.0229892631144703	[]	[]	0	hSpCas9	negative selection	2953796
140504822	140504845	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.10619394173326857	[4,4]	[3,4]	2	hSpCas9	positive selection	3022818
140505016	140505039	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	-0.753815660663765	[2,2]	[1,0]	-8	hSpCas9	positive selection	3022819
140504964	140504987	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.6918126547435133	[3,2]	[2,0]	-8	hSpCas9	positive selection	3022820
140504995	140505018	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.16512231291372556	[4,4]	[5,2]	3	hSpCas9	positive selection	3022821
140504822	140504845	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.24818347795436563	[4,4]	[4,3]	4	hSpCas9	positive selection	3090676
140505016	140505039	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	0.30987961526046676	[2,2]	[3,0]	5	hSpCas9	positive selection	3090677
140504964	140504987	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.22095454659454863	[3,3]	[2,1]	-3	hSpCas9	positive selection	3090678
140504995	140505018	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.09985039942494947	[4,4]	[3,2]	1	hSpCas9	positive selection	3090679
140504082	140504105	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.15929412848530838	[136,136]	[0,0]	0	hSpCas9	positive selection	3394368
140503877	140503900	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3394369
140504795	140504818	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	4.087401210003523	[8,8]	[0,0]	9	hSpCas9	positive selection	3394370
140504821	140504844	X	+	26780180	HT29	viability (Avana library 4 designs)	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.285252550341755	[]	[]	1	hSpCas9	negative selection	3461426
140505016	140505039	X	-	26780180	HT29	viability (Avana library 4 designs)	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	1.78258141799715	[]	[]	6	hSpCas9	negative selection	3461427
140504964	140504987	X	-	26780180	HT29	viability (Avana library 4 designs)	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	1.79010145174634	[]	[]	6	hSpCas9	negative selection	3461428
140504995	140505018	X	-	26780180	HT29	viability (Avana library 4 designs)	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	-0.658942287033884	[]	[]	-8	hSpCas9	negative selection	3461429
140504964	140504987	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-1.07511277486378	[]	[]	-1	hSpCas9	negative selection	3562262
140505016	140505039	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	3.8565991547573	[]	[]	6	hSpCas9	negative selection	3562263
140504995	140505018	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	6.65565559649887	[]	[]	9	hSpCas9	negative selection	3562264
140504821	140504844	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	2.91293702595467	[]	[]	4	hSpCas9	negative selection	3562265
140504734	140504757	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCTTGCCTGCGCCTCCCGGGG	SOX3	ENSG00000134595	4.92946809930216	[]	[]	8	hSpCas9	negative selection	3562266
140504515	140504538	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCGGTCAGCAGTTTCCAGTCGG	SOX3	ENSG00000134595	3.37957582678832	[]	[]	5	hSpCas9	negative selection	3562267
140504964	140504987	X	-	26780180	A375	viability (Avana lentiGuide)	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	4.17878198944967	[]	[]	4	hSpCas9	negative selection	3670921
140505016	140505039	X	-	26780180	A375	viability (Avana lentiGuide)	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	4.10393825219792	[]	[]	4	hSpCas9	negative selection	3670922
140504995	140505018	X	-	26780180	A375	viability (Avana lentiGuide)	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	-1.0082609787228	[]	[]	-1	hSpCas9	negative selection	3670923
140504821	140504844	X	+	26780180	A375	viability (Avana lentiGuide)	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	1.34423944239104	[]	[]	1	hSpCas9	negative selection	3670924
140504734	140504757	X	+	26780180	A375	viability (Avana lentiGuide)	ACTCTTGCCTGCGCCTCCCGGGG	SOX3	ENSG00000134595	-0.76924094169805	[]	[]	-1	hSpCas9	negative selection	3670925
140504515	140504538	X	+	26780180	A375	viability (Avana lentiGuide)	GTCGGTCAGCAGTTTCCAGTCGG	SOX3	ENSG00000134595	0.834108477790954	[]	[]	1	hSpCas9	negative selection	3670926
140504964	140504987	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.08885552013010284	[4]	[5,4]	2	hSpCas9	positive selection	3779528
140505016	140505039	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	0.1401727959649472	[4]	[5,4]	4	hSpCas9	positive selection	3779529
140504995	140505018	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.3693578388325203	[4]	[6,6]	9	hSpCas9	positive selection	3779530
140504821	140504844	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.22850477686347986	[5]	[6,6]	6	hSpCas9	positive selection	3779531
140504734	140504757	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCTTGCCTGCGCCTCCCGGGG	SOX3	ENSG00000134595	0.41022739657012186	[4]	[6,5]	9	hSpCas9	positive selection	3779532
140504515	140504538	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCGGTCAGCAGTTTCCAGTCGG	SOX3	ENSG00000134595	0.04981833127584227	[4]	[5,4]	1	hSpCas9	positive selection	3779533
140504964	140504987	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.01303875542318048	[5]	[3,5]	0	hSpCas9	positive selection	3888135
140505016	140505039	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCAGGTGCGAGAAGCCCGCGG	SOX3	ENSG00000134595	-1.2543100850877613	[4]	[2,0]	-9	hSpCas9	positive selection	3888136
140504995	140505018	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTTCCTGCTGATTTGGCGCGG	SOX3	ENSG00000134595	0.09650338616671165	[5]	[4,5]	2	hSpCas9	positive selection	3888137
140504821	140504844	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.11919608044863961	[6]	[5,5]	2	hSpCas9	positive selection	3888138
140504734	140504757	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCTTGCCTGCGCCTCCCGGGG	SOX3	ENSG00000134595	0.04634020713552318	[5]	[5,3]	1	hSpCas9	positive selection	3888139
140504515	140504538	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCGGTCAGCAGTTTCCAGTCGG	SOX3	ENSG00000134595	0.22442471541848827	[6]	[5,6]	6	hSpCas9	positive selection	3888140
140504795	140504818	X	-	26780180	A375	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.750210763004778	[]	[]	2	hSpCas9	negative selection	3998244
140504236	140504259	X	+	26780180	A375	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	1.74977649085679	[]	[]	9	hSpCas9	negative selection	3998245
140503877	140503900	X	-	26780180	A375	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.507381394692167	[]	[]	1	hSpCas9	negative selection	3998246
140504082	140504105	X	-	26780180	A375	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.820397108366495	[]	[]	3	hSpCas9	negative selection	3998247
140504238	140504261	X	-	26780180	A375	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	1.22944014320229	[]	[]	6	hSpCas9	negative selection	3998248
140504464	140504487	X	+	26780180	A375	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	1.57184228754299	[]	[]	8	hSpCas9	negative selection	3998249
140504795	140504818	X	-	26780180	HT29	viability (GeCKOv2 library)	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.670357881825099	[]	[]	2	hSpCas9	negative selection	4106210
140504236	140504259	X	+	26780180	HT29	viability (GeCKOv2 library)	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	1.24709859979744	[]	[]	6	hSpCas9	negative selection	4106211
140503877	140503900	X	-	26780180	HT29	viability (GeCKOv2 library)	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	1.10819439604777	[]	[]	5	hSpCas9	negative selection	4106212
140504082	140504105	X	-	26780180	HT29	viability (GeCKOv2 library)	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	1.4306795518526	[]	[]	7	hSpCas9	negative selection	4106213
140504238	140504261	X	-	26780180	HT29	viability (GeCKOv2 library)	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	2.1285660993585	[]	[]	9	hSpCas9	negative selection	4106214
140504464	140504487	X	+	26780180	HT29	viability (GeCKOv2 library)	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	1.1587532459761	[]	[]	5	hSpCas9	negative selection	4106215
140504238	140504261	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.655080973318009	[2]	[1,0]	-9	hSpCas9	positive selection	4299887
140504464	140504487	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.5392324607268691	[3]	[3,3]	9	hSpCas9	positive selection	4299888
140504236	140504259	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.06953298206218891	[3]	[3,1]	1	hSpCas9	positive selection	4299889
140504082	140504105	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.40198260373224437	[3]	[2,0]	-7	hSpCas9	positive selection	4364139
140503877	140503900	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.08890567573683145	[1]	[1,1]	-2	hSpCas9	positive selection	4364140
140504795	140504818	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.47396633329948246	[1]	[0,0]	-8	hSpCas9	positive selection	4364141
140504300	140504322	X	+	27760321	OCIAML3	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.7439483358438348	[924,693]	[1023,1086]	8	hSpCas9	negative selection	4442230
140504714	140504736	X	-	27760321	OCIAML3	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.15456713220890428	[519,416]	[365,456]	1	hSpCas9	negative selection	4442231
140504775	140504797	X	-	27760321	OCIAML3	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.5955546222391542	[723,487]	[634,800]	7	hSpCas9	negative selection	4442232
140504794	140504816	X	-	27760321	OCIAML3	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	1.1540568500540949	[684,606]	[1075,1182]	9	hSpCas9	negative selection	4442233
140504915	140504937	X	-	27760321	OCIAML3	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.5115280128581995	[372,286]	[349,384]	6	hSpCas9	negative selection	4442234
140504300	140504322	X	+	27760321	OCIAML2	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.4875915066958574	[924,693]	[742,1130]	6	hSpCas9	negative selection	4525693
140504714	140504736	X	-	27760321	OCIAML2	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.5315748224105509	[519,416]	[504,596]	7	hSpCas9	negative selection	4525694
140504775	140504797	X	-	27760321	OCIAML2	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.3163696426552055	[723,487]	[565,650]	4	hSpCas9	negative selection	4525695
140504794	140504816	X	-	27760321	OCIAML2	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.629681173923286	[684,606]	[713,929]	8	hSpCas9	negative selection	4525696
140504915	140504937	X	-	27760321	OCIAML2	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.2400550495324071	[372,286]	[340,275]	3	hSpCas9	negative selection	4525697
140504300	140504322	X	+	27760321	MV411	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.6443359501173462	[924,693]	[480,1348]	5	hSpCas9	negative selection	4609156
140504714	140504736	X	-	27760321	MV411	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.589674032953207	[519,416]	[452,476]	4	hSpCas9	negative selection	4609157
140504775	140504797	X	-	27760321	MV411	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.6055838557438856	[723,487]	[549,676]	4	hSpCas9	negative selection	4609158
140504794	140504816	X	-	27760321	MV411	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.43112531693173195	[684,606]	[341,921]	3	hSpCas9	negative selection	4609159
140504915	140504937	X	-	27760321	MV411	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.8778500236709815	[372,286]	[409,377]	6	hSpCas9	negative selection	4609160
140504300	140504322	X	+	27760321	HL60	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.29077103890579026	[924,693]	[821,780]	3	hSpCas9	negative selection	4692619
140504714	140504736	X	-	27760321	HL60	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.4514918280722001	[519,416]	[464,578]	5	hSpCas9	negative selection	4692620
140504775	140504797	X	-	27760321	HL60	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.531922876446262	[723,487]	[578,841]	6	hSpCas9	negative selection	4692621
140504794	140504816	X	-	27760321	HL60	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.1730696375731634	[684,606]	[625,559]	2	hSpCas9	negative selection	4692622
140504915	140504937	X	-	27760321	HL60	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.435198021391492	[372,286]	[337,386]	5	hSpCas9	negative selection	4692623
140504300	140504322	X	+	27760321	HT1080	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	1.2967123625834076	[693,541]	[590,619]	7	hSpCas9	negative selection	4776082
140504714	140504736	X	-	27760321	HT1080	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	1.573190195242644	[416,325]	[364,522]	8	hSpCas9	negative selection	4776083
140504775	140504797	X	-	27760321	HT1080	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.28545808307000464	[487,380]	[262,153]	1	hSpCas9	negative selection	4776084
140504794	140504816	X	-	27760321	HT1080	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	1.0256320575481241	[606,473]	[382,498]	5	hSpCas9	negative selection	4776085
140504915	140504937	X	-	27760321	HT1080	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.3803126143193932	[286,223]	[89,178]	2	hSpCas9	negative selection	4776086
140504300	140504322	X	+	27760321	HT29	viability after 7 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.7024530513196403	[693,541]	[1343,1517,1030]	9	hSpCas9	negative selection	4859545
140504714	140504736	X	-	27760321	HT29	viability after 7 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.21304177970544352	[416,325]	[738,465,483]	3	hSpCas9	negative selection	4859546
140504775	140504797	X	-	27760321	HT29	viability after 7 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.31273362416095174	[487,380]	[772,722,598]	5	hSpCas9	negative selection	4859547
140504794	140504816	X	-	27760321	HT29	viability after 7 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.4006838697557955	[606,473]	[977,908,873]	6	hSpCas9	negative selection	4859548
140504915	140504937	X	-	27760321	HT29	viability after 7 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.47602658635476697	[286,223]	[652,286,457]	7	hSpCas9	negative selection	4859549
140504300	140504322	X	+	27760321	HT29	viability after 25 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.9024857089081209	[693,541]	[1233,1342,1394]	9	hSpCas9	negative selection	4943008
140504714	140504736	X	-	27760321	HT29	viability after 25 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.21057454137471343	[416,325]	[611,341,513]	2	hSpCas9	negative selection	4943009
140504775	140504797	X	-	27760321	HT29	viability after 25 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	-0.015160384934936932	[487,380]	[376,556,552]	0	hSpCas9	negative selection	4943010
140504794	140504816	X	-	27760321	HT29	viability after 25 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.576183674959768	[606,473]	[883,801,1095]	6	hSpCas9	negative selection	4943011
140504915	140504937	X	-	27760321	HT29	viability after 25 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	1.4308953159575073	[286,223]	[663,669,1062]	9	hSpCas9	negative selection	4943012
140504300	140504322	X	+	27760321	HT29	viability after 22 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.5389176082654399	[693,541]	[825,1443,847]	6	hSpCas9	negative selection	5026471
140504714	140504736	X	-	27760321	HT29	viability after 22 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.3874305160124628	[416,325]	[551,440,693]	4	hSpCas9	negative selection	5026472
140504775	140504797	X	-	27760321	HT29	viability after 22 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.08256198559759559	[487,380]	[584,606,400]	0	hSpCas9	negative selection	5026473
140504794	140504816	X	-	27760321	HT29	viability after 22 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.48801901809897164	[606,473]	[781,729,1121]	5	hSpCas9	negative selection	5026474
140504915	140504937	X	-	27760321	HT29	viability after 22 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	1.0986588755054798	[286,223]	[812,421,657]	9	hSpCas9	negative selection	5026475
140504300	140504322	X	+	27760321	HT29	viability after 19 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.4931479242149943	[693,541]	[1190,1208,618]	5	hSpCas9	negative selection	5109934
140504714	140504736	X	-	27760321	HT29	viability after 19 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.9383947384292607	[416,325]	[850,211,1361]	8	hSpCas9	negative selection	5109935
140504775	140504797	X	-	27760321	HT29	viability after 19 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.3462677440290768	[487,380]	[602,367,909]	3	hSpCas9	negative selection	5109936
140504794	140504816	X	-	27760321	HT29	viability after 19 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.6986098673158727	[606,473]	[1017,810,1174]	7	hSpCas9	negative selection	5109937
140504915	140504937	X	-	27760321	HT29	viability after 19 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	1.1660061825958314	[286,223]	[938,554,507]	9	hSpCas9	negative selection	5109938
140504300	140504322	X	+	27760321	HT29	viability after 16 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.8448392763944965	[693,541]	[1064,1423,1214]	8	hSpCas9	negative selection	5193397
140504714	140504736	X	-	27760321	HT29	viability after 16 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.7229855938306834	[416,325]	[537,733,770]	8	hSpCas9	negative selection	5193398
140504775	140504797	X	-	27760321	HT29	viability after 16 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.7442935901231769	[487,380]	[918,767,766]	8	hSpCas9	negative selection	5193399
140504794	140504816	X	-	27760321	HT29	viability after 16 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.8212943312150043	[606,473]	[1072,1218,909]	8	hSpCas9	negative selection	5193400
140504915	140504937	X	-	27760321	HT29	viability after 16 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.6168694473099406	[286,223]	[288,588,418]	7	hSpCas9	negative selection	5193401
140504300	140504322	X	+	27760321	HT29	viability after 13 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.902502121047875	[693,541]	[1087,1761,1180]	9	hSpCas9	negative selection	5276860
140504714	140504736	X	-	27760321	HT29	viability after 13 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.45927172436722924	[416,325]	[612,339,810]	6	hSpCas9	negative selection	5276861
140504775	140504797	X	-	27760321	HT29	viability after 13 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.4645329833188433	[487,380]	[672,809,608]	6	hSpCas9	negative selection	5276862
140504794	140504816	X	-	27760321	HT29	viability after 13 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.6482155992712539	[606,473]	[1193,982,782]	8	hSpCas9	negative selection	5276863
140504915	140504937	X	-	27760321	HT29	viability after 13 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.8511506733559191	[286,223]	[533,432,630]	9	hSpCas9	negative selection	5276864
140504300	140504322	X	+	27760321	HT29	viability after 10 days	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	0.8943539724082192	[693,541]	[1748,1299,1253]	9	hSpCas9	negative selection	5360323
140504714	140504736	X	-	27760321	HT29	viability after 10 days	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.051180645677117866	[416,325]	[297,472,569]	0	hSpCas9	negative selection	5360324
140504775	140504797	X	-	27760321	HT29	viability after 10 days	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.6747785562523363	[487,380]	[1146,700,747]	8	hSpCas9	negative selection	5360325
140504794	140504816	X	-	27760321	HT29	viability after 10 days	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	0.6823069770751835	[606,473]	[1305,948,991]	8	hSpCas9	negative selection	5360326
140504915	140504937	X	-	27760321	HT29	viability after 10 days	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	0.9395264106124979	[286,223]	[583,636,614]	9	hSpCas9	negative selection	5360327
140504300	140504322	X	+	27760321	MOLM13	viability	ACGCCCACCGGACTGCTGGCGG	SOX3	ENSG00000134595	1.4181495342638781	[924,693]	[1374,1069]	8	hSpCas9	negative selection	5443786
140504714	140504736	X	-	27760321	MOLM13	viability	GTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	1.1304136402061553	[519,416]	[832,355]	7	hSpCas9	negative selection	5443787
140504775	140504797	X	-	27760321	MOLM13	viability	GGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.1932702153145938	[723,487]	[705,827]	8	hSpCas9	negative selection	5443788
140504794	140504816	X	-	27760321	MOLM13	viability	TGAACTCAAGAACCCCGTAGGG	SOX3	ENSG00000134595	1.4481052577852829	[684,606]	[618,1310]	8	hSpCas9	negative selection	5443789
140504915	140504937	X	-	27760321	MOLM13	viability	CCGCTCCGACGGAGTCCCAGGG	SOX3	ENSG00000134595	1.9504378789364831	[372,286]	[1342,178]	9	hSpCas9	negative selection	5443790
140504954	140504977	X	+	27661255	K562	viability	GCCAGCGAGTCCGGCGGGAAGGG	SOX3	ENSG00000134595	-0.13637818259505696	[303,310]	[224,221]	-5	dCas9-KRAB	negative selection	5513567
140504699	140504722	X	-	27661255	K562	viability	GCCGGCGGCGCGAACTCGGGCGG	SOX3	ENSG00000134595	-0.07588781388247745	[300,316]	[220,244]	-3	dCas9-KRAB	negative selection	5513568
140504238	140504261	X	-	27260156	BXPC3	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.11653197638399215	[298]	[310,352,325,368]	2	hSpCas9	negative selection	5572347
140504464	140504487	X	+	27260156	BXPC3	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.0661050192771282	[487]	[409,561,563,619]	1	hSpCas9	negative selection	5572348
140504236	140504259	X	+	27260156	BXPC3	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.3238848766451281	[561]	[697,634,769,859]	7	hSpCas9	negative selection	5572349
140504082	140504105	X	-	27260156	BXPC3	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.1762108226717191	[547]	[508,413,525,591]	-4	hSpCas9	negative selection	5636599
140503877	140503900	X	-	27260156	BXPC3	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.08297857652408447	[180]	[138,189,272,207]	1	hSpCas9	negative selection	5636600
140504795	140504818	X	-	27260156	BXPC3	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.23941479895132645	[81]	[66,44,57,128]	-5	hSpCas9	negative selection	5636601
140504238	140504261	X	-	27260156	A673	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.11906570905207736	[298]	[303,314,392,304]	-3	hSpCas9	negative selection	5693598
140504464	140504487	X	+	27260156	A673	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.23879308172107808	[487]	[594,742,715,697]	5	hSpCas9	negative selection	5693599
140504236	140504259	X	+	27260156	A673	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.014503940256139242	[561]	[815,535,720,614]	0	hSpCas9	negative selection	5693600
140504082	140504105	X	-	27260156	A673	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.11688995891721442	[547]	[588,644,437,760]	-3	hSpCas9	negative selection	5757850
140503877	140503900	X	-	27260156	A673	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.313650090270849	[180]	[261,267,204,348]	7	hSpCas9	negative selection	5757851
140504795	140504818	X	-	27260156	A673	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.1544359320031501	[81]	[103,87,83,78]	-4	hSpCas9	negative selection	5757852
140504238	140504261	X	-	27260156	A375	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.28147206443611394	[298]	[458,299,364,540]	4	hSpCas9	negative selection	5814849
140504464	140504487	X	+	27260156	A375	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.3159278472592191	[487]	[758,1034,599,510]	4	hSpCas9	negative selection	5814850
140504236	140504259	X	+	27260156	A375	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.1558385018481454	[561]	[872,701,933,444]	2	hSpCas9	negative selection	5814851
140504082	140504105	X	-	27260156	A375	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.15126865773556486	[547]	[460,797,725,848]	2	hSpCas9	negative selection	5879101
140503877	140503900	X	-	27260156	A375	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.36322220617073353	[180]	[183,222,425,248]	5	hSpCas9	negative selection	5879102
140504795	140504818	X	-	27260156	A375	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.6659511738868571	[81]	[47,123,63,18]	-7	hSpCas9	negative selection	5879103
140504238	140504261	X	-	27260156	COLO741	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.14372214983557507	[298]	[516,360,396]	3	hSpCas9	negative selection	5936100
140504464	140504487	X	+	27260156	COLO741	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.07936164301194482	[487]	[739,518,717]	1	hSpCas9	negative selection	5936101
140504236	140504259	X	+	27260156	COLO741	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.08202800823186698	[561]	[595,768,662]	-2	hSpCas9	negative selection	5936102
140504082	140504105	X	-	27260156	COLO741	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.029632311288311813	[547]	[745,736,585]	0	hSpCas9	negative selection	6000352
140503877	140503900	X	-	27260156	COLO741	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.19097828875267542	[180]	[363,231,207]	4	hSpCas9	negative selection	6000353
140504795	140504818	X	-	27260156	COLO741	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.09965540694032038	[81]	[108,152,76]	2	hSpCas9	negative selection	6000354
140504238	140504261	X	-	27260156	CAL120	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.022174549111096287	[298]	[351,317,457]	0	hSpCas9	negative selection	6057351
140504464	140504487	X	+	27260156	CAL120	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.09319674811962103	[487]	[638,835,469]	1	hSpCas9	negative selection	6057352
140504236	140504259	X	+	27260156	CAL120	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.13536461491708796	[561]	[704,675,910]	2	hSpCas9	negative selection	6057353
140504082	140504105	X	-	27260156	CAL120	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.06598448155009978	[547]	[401,849,839]	1	hSpCas9	negative selection	6121603
140503877	140503900	X	-	27260156	CAL120	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.020714211639845104	[180]	[328,114,255]	0	hSpCas9	negative selection	6121604
140504795	140504818	X	-	27260156	CAL120	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.1817010730985711	[81]	[51,169,42]	-3	hSpCas9	negative selection	6121605
140504238	140504261	X	-	27260156	CADOES1	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.4583290054650483	[298]	[300,316,689,213]	7	hSpCas9	negative selection	6178602
140504464	140504487	X	+	27260156	CADOES1	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.021032784531586766	[487]	[489,443,511,338]	0	hSpCas9	negative selection	6178603
140504236	140504259	X	+	27260156	CADOES1	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.33953556771712384	[561]	[410,500,391,345]	-5	hSpCas9	negative selection	6178604
140504082	140504105	X	-	27260156	CADOES1	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.01622800993929069	[547]	[671,445,478,414]	0	hSpCas9	negative selection	6242854
140503877	140503900	X	-	27260156	CADOES1	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.35405278793024797	[180]	[167,140,130,84]	-6	hSpCas9	negative selection	6242855
140504795	140504818	X	-	27260156	CADOES1	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.2614406150141426	[81]	[113,39,44,54]	-4	hSpCas9	negative selection	6242856
140504238	140504261	X	-	27260156	EWS502	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.07683845752111285	[298]	[245,312,244,408]	-1	hSpCas9	negative selection	6299853
140504464	140504487	X	+	27260156	EWS502	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.016805788307614943	[487]	[512,496,502,582]	0	hSpCas9	negative selection	6299854
140504236	140504259	X	+	27260156	EWS502	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.2503077112219977	[561]	[442,407,593,571]	-4	hSpCas9	negative selection	6299855
140504082	140504105	X	-	27260156	EWS502	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.016428142345131708	[547]	[440,552,624,700]	0	hSpCas9	negative selection	6364105
140503877	140503900	X	-	27260156	EWS502	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.41751992074480193	[180]	[212,306,270,233]	7	hSpCas9	negative selection	6364106
140504795	140504818	X	-	27260156	EWS502	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.31880707935097297	[81]	[41,105,94,34]	-5	hSpCas9	negative selection	6364107
140504238	140504261	X	-	27260156	EW8	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.07128600654306938	[298]	[258,335,150,289]	1	hSpCas9	negative selection	6421104
140504464	140504487	X	+	27260156	EW8	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.34506010845296786	[487]	[610,450,374,603]	6	hSpCas9	negative selection	6421105
140504236	140504259	X	+	27260156	EW8	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.10581655810683632	[561]	[690,309,443,542]	2	hSpCas9	negative selection	6421106
140504082	140504105	X	-	27260156	EW8	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.17728586193156695	[547]	[294,484,407,368]	-3	hSpCas9	negative selection	6485356
140503877	140503900	X	-	27260156	EW8	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.0291121701476722	[180]	[159,208,52,193]	0	hSpCas9	negative selection	6485357
140504795	140504818	X	-	27260156	EW8	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.4333728361653475	[81]	[56,138,49,115]	7	hSpCas9	negative selection	6485358
140504238	140504261	X	-	27260156	CORL105	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.4755797437811995	[298]	[513,510,471,447]	8	hSpCas9	negative selection	6542355
140504464	140504487	X	+	27260156	CORL105	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.3328136815099289	[487]	[607,715,871,701]	6	hSpCas9	negative selection	6542356
140504236	140504259	X	+	27260156	CORL105	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.14513836260354285	[561]	[691,710,690,808]	2	hSpCas9	negative selection	6542357
140504082	140504105	X	-	27260156	CORL105	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.08024712039281706	[547]	[594,501,1001,664]	1	hSpCas9	negative selection	6606607
140503877	140503900	X	-	27260156	CORL105	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.3431909326620375	[180]	[216,220,325,318]	6	hSpCas9	negative selection	6606608
140504795	140504818	X	-	27260156	CORL105	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.030788616288818904	[81]	[153,41,112,72]	0	hSpCas9	negative selection	6606609
140504238	140504261	X	-	27260156	HS294T	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.5381533656016197	[298]	[142,183,171,174]	7	hSpCas9	negative selection	6663606
140504464	140504487	X	+	27260156	HS294T	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.5369170549132646	[487]	[243,429,171,239]	7	hSpCas9	negative selection	6663607
140504236	140504259	X	+	27260156	HS294T	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.42555467014332615	[561]	[262,192,242,509]	6	hSpCas9	negative selection	6663608
140504082	140504105	X	-	27260156	HS294T	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.20025934939833756	[547]	[144,150,231,219]	-3	hSpCas9	negative selection	6727858
140503877	140503900	X	-	27260156	HS294T	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.15169839239513383	[180]	[102,90,49,60]	2	hSpCas9	negative selection	6727859
140504795	140504818	X	-	27260156	HS294T	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.54735190114462	[81]	[25,63,27,72]	7	hSpCas9	negative selection	6727860
140504238	140504261	X	-	27260156	HCC44	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.3119532566271855	[298]	[490,315,482,417]	5	hSpCas9	negative selection	6784857
140504464	140504487	X	+	27260156	HCC44	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.0902968021588409	[487]	[584,527,990,327]	1	hSpCas9	negative selection	6784858
140504236	140504259	X	+	27260156	HCC44	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.0697653785620484	[561]	[581,421,659,780]	-1	hSpCas9	negative selection	6784859
140504082	140504105	X	-	27260156	HCC44	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.2653589548827926	[547]	[882,786,809,518]	4	hSpCas9	negative selection	6849109
140503877	140503900	X	-	27260156	HCC44	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.3947000298810637	[180]	[329,141,453,205]	6	hSpCas9	negative selection	6849110
140504795	140504818	X	-	27260156	HCC44	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.8705365306440807	[81]	[22,10,43,123]	-8	hSpCas9	negative selection	6849111
140504238	140504261	X	-	27260156	G402	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.14371435022816803	[298]	[526,182,244,381]	-2	hSpCas9	negative selection	6906108
140504464	140504487	X	+	27260156	G402	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.4100479000958439	[487]	[701,282,471,364]	-5	hSpCas9	negative selection	6906109
140504236	140504259	X	+	27260156	G402	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.369058396751051	[561]	[1370,979,679,597]	4	hSpCas9	negative selection	6906110
140504082	140504105	X	-	27260156	G402	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.09427769015515636	[547]	[1004,628,845,423]	1	hSpCas9	negative selection	6970360
140503877	140503900	X	-	27260156	G402	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.5433311759636889	[180]	[630,321,249,136]	6	hSpCas9	negative selection	6970361
140504795	140504818	X	-	27260156	G402	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-1.2586881377143464	[81]	[83,62,18,9]	-8	hSpCas9	negative selection	6970362
140504238	140504261	X	-	27260156	L33	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.4053087774539573	[298]	[367,149,267,423]	8	hSpCas9	negative selection	7027359
140504464	140504487	X	+	27260156	L33	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.21040914548118136	[487]	[588,255,340,501]	4	hSpCas9	negative selection	7027360
140504236	140504259	X	+	27260156	L33	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.3264911515070297	[561]	[638,259,614,570]	7	hSpCas9	negative selection	7027361
140504082	140504105	X	-	27260156	L33	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.4399006232909242	[547]	[396,170,277,359]	-8	hSpCas9	negative selection	7091611
140503877	140503900	X	-	27260156	L33	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.3927733176464958	[180]	[154,68,59,131]	-7	hSpCas9	negative selection	7091612
140504795	140504818	X	-	27260156	L33	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.24570134929557996	[81]	[88,47,60,85]	5	hSpCas9	negative selection	7091613
140504238	140504261	X	-	27260156	K562	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.5247081134951312	[298]	[328,238,662,292]	6	hSpCas9	negative selection	7148610
140504464	140504487	X	+	27260156	K562	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.0950582571894634	[487]	[535,377,455,477]	1	hSpCas9	negative selection	7148611
140504236	140504259	X	+	27260156	K562	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.4275115957508291	[561]	[580,900,768,458]	5	hSpCas9	negative selection	7148612
140504082	140504105	X	-	27260156	K562	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.22354741194933828	[547]	[199,435,589,420]	-3	hSpCas9	negative selection	7212862
140503877	140503900	X	-	27260156	K562	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.04019678422363082	[180]	[174,127,267,95]	0	hSpCas9	negative selection	7212863
140504795	140504818	X	-	27260156	K562	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-1.2873293571932187	[81]	[23,11,63,18]	-8	hSpCas9	negative selection	7212864
140504238	140504261	X	-	27260156	HT29	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.2823655202591774	[298]	[266,315,298,308]	-5	hSpCas9	negative selection	7269861
140504464	140504487	X	+	27260156	HT29	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.21950344035924066	[487]	[816,734,579,644]	4	hSpCas9	negative selection	7269862
140504236	140504259	X	+	27260156	HT29	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.10403205258290449	[561]	[960,620,583,768]	2	hSpCas9	negative selection	7269863
140504082	140504105	X	-	27260156	HT29	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.09787120204067014	[547]	[664,680,761,411]	-2	hSpCas9	negative selection	7334113
140503877	140503900	X	-	27260156	HT29	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.3579431374646702	[180]	[313,399,245,189]	7	hSpCas9	negative selection	7334114
140504795	140504818	X	-	27260156	HT29	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.05522611568832003	[81]	[147,29,94,106]	-1	hSpCas9	negative selection	7334115
140504238	140504261	X	-	27260156	MHHES1	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.37218066843250264	[298]	[355,543,406,428]	6	hSpCas9	negative selection	7391112
140504464	140504487	X	+	27260156	MHHES1	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.016033325665142727	[487]	[753,587,515,412]	0	hSpCas9	negative selection	7391113
140504236	140504259	X	+	27260156	MHHES1	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.08670188634446616	[561]	[751,641,561,467]	-2	hSpCas9	negative selection	7391114
140504082	140504105	X	-	27260156	MHHES1	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.14846651083580814	[547]	[817,594,404,454]	-3	hSpCas9	negative selection	7455364
140503877	140503900	X	-	27260156	MHHES1	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.17879193669146187	[180]	[125,229,275,264]	3	hSpCas9	negative selection	7455365
140504795	140504818	X	-	27260156	MHHES1	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.5135511178700165	[81]	[125,81,103,191]	8	hSpCas9	negative selection	7455366
140504238	140504261	X	-	27260156	MEWO	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.0029111840043369863	[298]	[358,260,232]	0	hSpCas9	negative selection	7512363
140504464	140504487	X	+	27260156	MEWO	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.022554549511420253	[487]	[560,459,388]	0	hSpCas9	negative selection	7512364
140504236	140504259	X	+	27260156	MEWO	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.10411808942321377	[561]	[622,459,623]	2	hSpCas9	negative selection	7512365
140504082	140504105	X	-	27260156	MEWO	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.0350727698463682	[547]	[381,531,633]	0	hSpCas9	negative selection	7576615
140503877	140503900	X	-	27260156	MEWO	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.0827922205456808	[180]	[178,160,197]	1	hSpCas9	negative selection	7576616
140504795	140504818	X	-	27260156	MEWO	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.18513135488141463	[81]	[69,47,84]	-4	hSpCas9	negative selection	7576617
140504238	140504261	X	-	27260156	LNCAPCLONEFGC	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.5937038487330072	[298]	[368,446,489,338]	8	hSpCas9	negative selection	7633614
140504464	140504487	X	+	27260156	LNCAPCLONEFGC	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.232628096172546	[487]	[510,519,691,379]	3	hSpCas9	negative selection	7633615
140504236	140504259	X	+	27260156	LNCAPCLONEFGC	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.22953063781843885	[561]	[726,566,592,498]	3	hSpCas9	negative selection	7633616
140504082	140504105	X	-	27260156	LNCAPCLONEFGC	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.2215362408069423	[547]	[451,441,825,642]	3	hSpCas9	negative selection	7697866
140503877	140503900	X	-	27260156	LNCAPCLONEFGC	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.31375276640361727	[180]	[113,237,260,209]	5	hSpCas9	negative selection	7697867
140504795	140504818	X	-	27260156	LNCAPCLONEFGC	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.059832017832804674	[81]	[84,6,136,93]	0	hSpCas9	negative selection	7697868
140504238	140504261	X	-	27260156	PANC0327	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.3070022206551246	[298]	[416,485,178,218]	4	hSpCas9	negative selection	7754865
140504464	140504487	X	+	27260156	PANC0327	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.20977066560018634	[487]	[435,331,474,266]	-3	hSpCas9	negative selection	7754866
140504236	140504259	X	+	27260156	PANC0327	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.04638556347257444	[561]	[757,327,469,549]	0	hSpCas9	negative selection	7754867
140504082	140504105	X	-	27260156	PANC0327	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.33531902418168	[547]	[595,721,556,565]	5	hSpCas9	negative selection	7819117
140503877	140503900	X	-	27260156	PANC0327	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.2919380020195148	[180]	[209,123,299,163]	4	hSpCas9	negative selection	7819118
140504795	140504818	X	-	27260156	PANC0327	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.4950947176966145	[81]	[82,86,98,141]	7	hSpCas9	negative selection	7819119
140504238	140504261	X	-	27260156	NCIH2009	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	1.1092074255651814	[298]	[1106,721,916]	9	hSpCas9	negative selection	7876116
140504464	140504487	X	+	27260156	NCIH2009	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.3903312692085584	[487]	[1101,816,802]	5	hSpCas9	negative selection	7876117
140504236	140504259	X	+	27260156	NCIH2009	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.25836537874716803	[561]	[1117,957,774]	3	hSpCas9	negative selection	7876118
140504082	140504105	X	-	27260156	NCIH2009	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.01928884473703313	[547]	[768,618,939]	0	hSpCas9	negative selection	7940368
140503877	140503900	X	-	27260156	NCIH2009	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.22750928435605977	[180]	[289,228,142]	-3	hSpCas9	negative selection	7940369
140504795	140504818	X	-	27260156	NCIH2009	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.3411921377702338	[81]	[245,39,170]	5	hSpCas9	negative selection	7940370
140504238	140504261	X	-	27260156	NCIH1373	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	1.1597479279147245	[298]	[860,666,627,228]	9	hSpCas9	negative selection	7997367
140504464	140504487	X	+	27260156	NCIH1373	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.27775012468203414	[487]	[419,783,848,139]	2	hSpCas9	negative selection	7997368
140504236	140504259	X	+	27260156	NCIH1373	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.42976360560464777	[561]	[1397,806,560,186]	4	hSpCas9	negative selection	7997369
140504082	140504105	X	-	27260156	NCIH1373	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.010281377959890037	[547]	[366,575,818,176]	0	hSpCas9	negative selection	8061619
140503877	140503900	X	-	27260156	NCIH1373	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.7927486075297965	[180]	[225,141,534,133]	7	hSpCas9	negative selection	8061620
140504795	140504818	X	-	27260156	NCIH1373	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.398246024612233	[81]	[94,104,53,61]	4	hSpCas9	negative selection	8061621
140504238	140504261	X	-	27260156	PATU8902	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.3325622303067565	[298]	[478,331,797,397]	3	hSpCas9	negative selection	8118618
140504464	140504487	X	+	27260156	PATU8902	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.1650860354048285	[487]	[1027,876,466,740]	1	hSpCas9	negative selection	8118619
140504236	140504259	X	+	27260156	PATU8902	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.45430121635997023	[561]	[668,1458,1360,675]	5	hSpCas9	negative selection	8118620
140504082	140504105	X	-	27260156	PATU8902	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.15978985929388412	[547]	[913,982,789,715]	1	hSpCas9	negative selection	8182870
140503877	140503900	X	-	27260156	PATU8902	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.5648567264184586	[180]	[438,494,453,38]	6	hSpCas9	negative selection	8182871
140504795	140504818	X	-	27260156	PATU8902	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.19405289897200095	[81]	[269,53,38,186]	2	hSpCas9	negative selection	8182872
140504238	140504261	X	-	27260156	PANC1	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.07697205046070688	[298]	[243,302,339,209]	1	hSpCas9	negative selection	8239869
140504464	140504487	X	+	27260156	PANC1	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.02064868546168505	[487]	[407,491,390,376]	0	hSpCas9	negative selection	8239870
140504236	140504259	X	+	27260156	PANC1	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.19712100621707046	[561]	[246,393,594,437]	-3	hSpCas9	negative selection	8239871
140504082	140504105	X	-	27260156	PANC1	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.09506657005355143	[547]	[344,634,476,354]	-1	hSpCas9	negative selection	8304121
140503877	140503900	X	-	27260156	PANC1	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.16680912246799484	[180]	[86,132,165,283]	2	hSpCas9	negative selection	8304122
140504795	140504818	X	-	27260156	PANC1	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.031558244956367165	[81]	[31,115,74,62]	0	hSpCas9	negative selection	8304123
140504238	140504261	X	-	27260156	PANC0813	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.7465519545255104	[298]	[483,699,620,543]	9	hSpCas9	negative selection	8361120
140504464	140504487	X	+	27260156	PANC0813	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.1992553279669699	[487]	[802,668,563,610]	3	hSpCas9	negative selection	8361121
140504236	140504259	X	+	27260156	PANC0813	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.305340251485938	[561]	[826,748,1059,637]	5	hSpCas9	negative selection	8361122
140504082	140504105	X	-	27260156	PANC0813	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.048981400204911346	[547]	[787,738,527,456]	-1	hSpCas9	negative selection	8425372
140503877	140503900	X	-	27260156	PANC0813	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.6669599087104185	[180]	[229,287,218,587]	9	hSpCas9	negative selection	8425373
140504795	140504818	X	-	27260156	PANC0813	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	1.1049896964968646	[81]	[209,215,253,151]	9	hSpCas9	negative selection	8425374
140504238	140504261	X	-	27260156	RDES	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.255410157916473	[298]	[421,325,476,410]	4	hSpCas9	negative selection	8482371
140504464	140504487	X	+	27260156	RDES	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.05442635339877281	[487]	[593,452,576,717]	0	hSpCas9	negative selection	8482372
140504236	140504259	X	+	27260156	RDES	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.24606008461530404	[561]	[485,704,1006,951]	4	hSpCas9	negative selection	8482373
140504082	140504105	X	-	27260156	RDES	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.11158504263658392	[547]	[547,616,748,852]	1	hSpCas9	negative selection	8546623
140503877	140503900	X	-	27260156	RDES	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.8088928199010422	[180]	[322,341,420,375]	9	hSpCas9	negative selection	8546624
140504795	140504818	X	-	27260156	RDES	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.20870030375805104	[81]	[43,76,116,98]	-4	hSpCas9	negative selection	8546625
140504238	140504261	X	-	27260156	PC3	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.14250466744420331	[298]	[295,305,386,319]	3	hSpCas9	negative selection	8603622
140504464	140504487	X	+	27260156	PC3	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.12619928875866201	[487]	[302,386,1123,605]	3	hSpCas9	negative selection	8603623
140504236	140504259	X	+	27260156	PC3	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.2674891341001153	[561]	[362,566,1533,653]	6	hSpCas9	negative selection	8603624
140504082	140504105	X	-	27260156	PC3	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.14698909173042457	[547]	[276,380,787,709]	-3	hSpCas9	negative selection	8667874
140503877	140503900	X	-	27260156	PC3	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.1775586197899004	[180]	[104,182,220,158]	-4	hSpCas9	negative selection	8667875
140504795	140504818	X	-	27260156	PC3	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.6347828484033089	[81]	[40,63,53,49]	-9	hSpCas9	negative selection	8667876
140504238	140504261	X	-	27260156	PATU8988T	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.13342651510541093	[298]	[388,224,214,217]	-2	hSpCas9	negative selection	8724873
140504464	140504487	X	+	27260156	PATU8988T	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.3426449835129377	[487]	[585,736,390,701]	6	hSpCas9	negative selection	8724874
140504236	140504259	X	+	27260156	PATU8988T	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.34801678673741593	[561]	[327,563,525,288]	-5	hSpCas9	negative selection	8724875
140504082	140504105	X	-	27260156	PATU8988T	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.15206260634758395	[547]	[479,664,656,554]	2	hSpCas9	negative selection	8789125
140503877	140503900	X	-	27260156	PATU8988T	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.5565040275498867	[180]	[269,478,80,218]	8	hSpCas9	negative selection	8789126
140504795	140504818	X	-	27260156	PATU8988T	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.0031110070938646928	[81]	[118,47,56,91]	0	hSpCas9	negative selection	8789127
140504238	140504261	X	-	27260156	T47D	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.05590374785253249	[298]	[410,338,375,322]	1	hSpCas9	negative selection	8846124
140504464	140504487	X	+	27260156	T47D	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.1642069048905579	[487]	[686,567,596,704]	3	hSpCas9	negative selection	8846125
140504236	140504259	X	+	27260156	T47D	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.1291302176813992	[561]	[623,722,748,767]	2	hSpCas9	negative selection	8846126
140504082	140504105	X	-	27260156	T47D	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.24493126949935495	[547]	[597,446,544,573]	-5	hSpCas9	negative selection	8910376
140503877	140503900	X	-	27260156	T47D	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.24050072970389702	[180]	[244,164,265,329]	5	hSpCas9	negative selection	8910377
140504795	140504818	X	-	27260156	T47D	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.012971383266251468	[81]	[80,80,68,150]	0	hSpCas9	negative selection	8910378
140504238	140504261	X	-	27260156	SU8686	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.9143260471196535	[298]	[370,547,549,827]	9	hSpCas9	negative selection	8967375
140504464	140504487	X	+	27260156	SU8686	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.35794857486119025	[487]	[410,573,563,1019]	6	hSpCas9	negative selection	8967376
140504236	140504259	X	+	27260156	SU8686	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.3492291794727238	[561]	[600,634,783,862]	6	hSpCas9	negative selection	8967377
140504082	140504105	X	-	27260156	SU8686	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.2102813432067506	[547]	[463,371,520,544]	-4	hSpCas9	negative selection	9031627
140503877	140503900	X	-	27260156	SU8686	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.050267900777869245	[180]	[61,185,241,222]	-1	hSpCas9	negative selection	9031628
140504795	140504818	X	-	27260156	SU8686	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.35523219375649573	[81]	[71,87,92,179]	6	hSpCas9	negative selection	9031629
140504238	140504261	X	-	27260156	SKES1	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.012116221325363052	[298]	[359,345,313,204]	0	hSpCas9	negative selection	9088626
140504464	140504487	X	+	27260156	SKES1	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.1176916886230174	[487]	[762,405,415,539]	2	hSpCas9	negative selection	9088627
140504236	140504259	X	+	27260156	SKES1	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	-0.24738139728914962	[561]	[564,418,496,415]	-5	hSpCas9	negative selection	9088628
140504082	140504105	X	-	27260156	SKES1	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	0.0016720717435588783	[547]	[533,532,632,485]	0	hSpCas9	negative selection	9152878
140503877	140503900	X	-	27260156	SKES1	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.2759456240835225	[180]	[249,200,188,232]	6	hSpCas9	negative selection	9152879
140504795	140504818	X	-	27260156	SKES1	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.03949162937770456	[81]	[59,53,162,53]	0	hSpCas9	negative selection	9152880
140504238	140504261	X	-	27260156	TOV112D	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.3824271995802261	[298]	[519,273,210,533]	7	hSpCas9	negative selection	9209877
140504464	140504487	X	+	27260156	TOV112D	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	-0.2958178509848557	[487]	[352,536,395,337]	-5	hSpCas9	negative selection	9209878
140504236	140504259	X	+	27260156	TOV112D	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.23233188774964236	[561]	[868,784,602,440]	4	hSpCas9	negative selection	9209879
140504082	140504105	X	-	27260156	TOV112D	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.45344771135195194	[547]	[311,546,366,404]	-7	hSpCas9	negative selection	9274129
140503877	140503900	X	-	27260156	TOV112D	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.5692998742395414	[180]	[135,137,149,70]	-8	hSpCas9	negative selection	9274130
140504795	140504818	X	-	27260156	TOV112D	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	-0.2062572314656932	[81]	[52,86,39,105]	-4	hSpCas9	negative selection	9274131
140504238	140504261	X	-	27260156	TC71	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	-0.03475471540419073	[298]	[254,348,295,355]	-1	hSpCas9	negative selection	9331128
140504464	140504487	X	+	27260156	TC71	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.03265996342542495	[487]	[564,566,410,604]	0	hSpCas9	negative selection	9331129
140504236	140504259	X	+	27260156	TC71	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.03268519377839435	[561]	[665,583,561,655]	0	hSpCas9	negative selection	9331130
140504082	140504105	X	-	27260156	TC71	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.21657878425860008	[547]	[498,525,508,486]	-5	hSpCas9	negative selection	9395380
140503877	140503900	X	-	27260156	TC71	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	-0.25375569833910383	[180]	[147,163,163,175]	-6	hSpCas9	negative selection	9395381
140504795	140504818	X	-	27260156	TC71	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.08024481487231316	[81]	[132,60,94,80]	2	hSpCas9	negative selection	9395382
140504238	140504261	X	-	27260156	TC32	viability	GGCCAACGGCGCGTACTCGCTGG	SOX3	ENSG00000134595	0.5052870195894239	[298]	[384,327,427,466]	8	hSpCas9	negative selection	9452379
140504464	140504487	X	+	27260156	TC32	viability	GTGCACGGCGCGAAGTCGCTTGG	SOX3	ENSG00000134595	0.12599879934003055	[487]	[487,268,702,646]	2	hSpCas9	negative selection	9452380
140504236	140504259	X	+	27260156	TC32	viability	CACCAGCGAGTACGCGCCGTTGG	SOX3	ENSG00000134595	0.11384936215557195	[561]	[576,398,840,544]	2	hSpCas9	negative selection	9452381
140504082	140504105	X	-	27260156	TC32	viability	CTACATGAACGTCGCTGCCGCGG	SOX3	ENSG00000134595	-0.313069080314334	[547]	[363,252,694,440]	-5	hSpCas9	negative selection	9516631
140503877	140503900	X	-	27260156	TC32	viability	CACTCTCAGCGCGCGTGCCTCGG	SOX3	ENSG00000134595	0.488234110199965	[180]	[208,182,304,281]	8	hSpCas9	negative selection	9516632
140504795	140504818	X	-	27260156	TC32	viability	ACTGAACTCAAGAACCCCGTAGG	SOX3	ENSG00000134595	0.012227020053370286	[81]	[67,77,115,49]	0	hSpCas9	negative selection	9516633
140504260	140504283	X	-	27869803	HPAFII	viability after 27 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.0051963551430634	[124]	[282,5,NaN]	8	hSpCas9	negative selection	9607792
140504274	140504297	X	+	27869803	HPAFII	viability after 27 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	-0.3979954175268031	[305]	[60,172,NaN]	-3	hSpCas9	negative selection	9607793
140504378	140504401	X	-	27869803	HPAFII	viability after 27 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	1.7065535750634853	[31]	[103,13,NaN]	9	hSpCas9	negative selection	9607794
140504714	140504737	X	-	27869803	HPAFII	viability after 27 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.3142361522847248	[104]	[60,74,NaN]	2	hSpCas9	negative selection	9607795
140504845	140504868	X	+	27869803	HPAFII	viability after 27 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.6824923661771957	[198]	[150,181,NaN]	5	hSpCas9	negative selection	9607796
140504990	140505013	X	+	27869803	HPAFII	viability after 27 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.0169377239060775	[174]	[159,207,NaN]	8	hSpCas9	negative selection	9607797
140504260	140504283	X	-	27869803	HPAFII	viability after 15 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.336840838168587	[124]	[786,60,NaN]	9	hSpCas9	negative selection	9690241
140504274	140504297	X	+	27869803	HPAFII	viability after 15 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.6819743782148192	[305]	[489,550,NaN]	7	hSpCas9	negative selection	9690242
140504378	140504401	X	-	27869803	HPAFII	viability after 15 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.7965298691946892	[31]	[76,48,NaN]	8	hSpCas9	negative selection	9690243
140504714	140504737	X	-	27869803	HPAFII	viability after 15 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.6534697730758776	[104]	[195,165,NaN]	7	hSpCas9	negative selection	9690244
140504845	140504868	X	+	27869803	HPAFII	viability after 15 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.6943092365998698	[198]	[350,342,NaN]	7	hSpCas9	negative selection	9690245
140504990	140505013	X	+	27869803	HPAFII	viability after 15 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.18837638647685562	[174]	[328,142,NaN]	2	hSpCas9	negative selection	9690246
140504260	140504283	X	-	27869803	ASPC1	viability after 36 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.9418849865834986	[323]	[533,119,69]	8	hSpCas9	negative selection	9772690
140504274	140504297	X	+	27869803	ASPC1	viability after 36 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.5036350318911835	[1100]	[850,489,367]	5	hSpCas9	negative selection	9772691
140504378	140504401	X	-	27869803	ASPC1	viability after 36 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	0.7871556928121726	[115]	[104,101,18]	7	hSpCas9	negative selection	9772692
140504714	140504737	X	-	27869803	ASPC1	viability after 36 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.6993759796772048	[259]	[52,112,11]	-6	hSpCas9	negative selection	9772693
140504845	140504868	X	+	27869803	ASPC1	viability after 36 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.4542010401566119	[463]	[201,277,188]	4	hSpCas9	negative selection	9772694
140504990	140505013	X	+	27869803	ASPC1	viability after 36 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.14454183068976612	[299]	[47,204,38]	-1	hSpCas9	negative selection	9772695
140504260	140504283	X	-	27869803	PATU8988S	viability after 35 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.9345336260924413	[232]	[115,242,NaN]	8	hSpCas9	negative selection	9855139
140504274	140504297	X	+	27869803	PATU8988S	viability after 35 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.8188133067651001	[858]	[505,714,NaN]	8	hSpCas9	negative selection	9855140
140504378	140504401	X	-	27869803	PATU8988S	viability after 35 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-0.4485201503360008	[70]	[0,40,NaN]	-4	hSpCas9	negative selection	9855141
140504714	140504737	X	-	27869803	PATU8988S	viability after 35 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.12352618952747463	[185]	[128,33,NaN]	1	hSpCas9	negative selection	9855142
140504845	140504868	X	+	27869803	PATU8988S	viability after 35 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.24662900646802566	[516]	[264,228,NaN]	3	hSpCas9	negative selection	9855143
140504990	140505013	X	+	27869803	PATU8988S	viability after 35 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	-0.2869072312624369	[279]	[62,121,NaN]	-3	hSpCas9	negative selection	9855144
140504260	140504283	X	-	27869803	PATU8988S	viability after 31 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.6437235035718708	[232]	[116,180,NaN]	7	hSpCas9	negative selection	9937588
140504274	140504297	X	+	27869803	PATU8988S	viability after 31 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	1.0723738092724662	[858]	[542,945,NaN]	9	hSpCas9	negative selection	9937589
140504378	140504401	X	-	27869803	PATU8988S	viability after 31 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	-1.0836179359495741	[70]	[4,23,NaN]	-8	hSpCas9	negative selection	9937590
140504714	140504737	X	-	27869803	PATU8988S	viability after 31 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	0.17001327114629938	[185]	[93,69,NaN]	2	hSpCas9	negative selection	9937591
140504845	140504868	X	+	27869803	PATU8988S	viability after 31 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.3686389632422253	[516]	[303,217,NaN]	4	hSpCas9	negative selection	9937592
140504990	140505013	X	+	27869803	PATU8988S	viability after 31 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	0.37184947849836536	[279]	[114,181,NaN]	4	hSpCas9	negative selection	9937593
140504260	140504283	X	-	27869803	HPAFII	viability after 35 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	1.212558915295702	[124]	[275,0,NaN]	7	hSpCas9	negative selection	10020037
140504274	140504297	X	+	27869803	HPAFII	viability after 35 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	-0.49508049757588657	[305]	[52,173,NaN]	-3	hSpCas9	negative selection	10020038
140504378	140504401	X	-	27869803	HPAFII	viability after 35 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	1.2058041276610147	[31]	[66,3,NaN]	7	hSpCas9	negative selection	10020039
140504714	140504737	X	-	27869803	HPAFII	viability after 35 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.22580429864465779	[104]	[12,81,NaN]	-1	hSpCas9	negative selection	10020040
140504845	140504868	X	+	27869803	HPAFII	viability after 35 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	1.0795041072496072	[198]	[250,169,NaN]	7	hSpCas9	negative selection	10020041
140504990	140505013	X	+	27869803	HPAFII	viability after 35 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.4715827497651088	[174]	[97,411,NaN]	8	hSpCas9	negative selection	10020042
140504260	140504283	X	-	27869803	HPAFII	viability after 31 days	CGTACACGCACGTGAACGGCTGG	SOX3	ENSG00000134595	0.8224479086833487	[124]	[236,0,NaN]	6	hSpCas9	negative selection	10102486
140504274	140504297	X	+	27869803	HPAFII	viability after 31 days	GCGTGTACGTGTCCAGGCGCTGG	SOX3	ENSG00000134595	0.06433998176655709	[305]	[46,323,NaN]	0	hSpCas9	negative selection	10102487
140504378	140504401	X	-	27869803	HPAFII	viability after 31 days	GATAAGTACTCCCTGCCCAGCGG	SOX3	ENSG00000134595	2.2712124253904347	[31]	[157,8,NaN]	9	hSpCas9	negative selection	10102488
140504714	140504737	X	-	27869803	HPAFII	viability after 31 days	AGTAGTGCGAACGCAGCCGGCGG	SOX3	ENSG00000134595	-0.2969856506210269	[104]	[35,60,NaN]	-2	hSpCas9	negative selection	10102489
140504845	140504868	X	+	27869803	HPAFII	viability after 31 days	GGGAAGAAGGTGCGCCAGCGTGG	SOX3	ENSG00000134595	0.8179612042857224	[198]	[171,223,NaN]	6	hSpCas9	negative selection	10102490
140504990	140505013	X	+	27869803	HPAFII	viability after 31 days	ATGCTCCGCGCCAAATCAGCAGG	SOX3	ENSG00000134595	1.4250310791489518	[174]	[156,379,NaN]	9	hSpCas9	negative selection	10102491
140504775	140504798	X	-	28162770	P31FUJ	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	-0.1843036867231887	[233]	[241]	-2	hSpCas9	negative selection	10240815
140503766	140503789	X	-	28162770	P31FUJ	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-0.17204817333528252	[278]	[290]	-2	hSpCas9	negative selection	10240816
140504999	140505022	X	+	28162770	P31FUJ	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.01833011236312343	[141]	[168]	0	hSpCas9	negative selection	10240817
140504964	140504987	X	-	28162770	P31FUJ	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.12166641854691884	[376]	[481]	1	hSpCas9	negative selection	10240818
140504848	140504871	X	+	28162770	P31FUJ	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.4999755927883942	[206]	[343]	5	hSpCas9	negative selection	10240819
140504821	140504844	X	+	28162770	P31FUJ	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.033843454971794085	[132]	[159]	0	hSpCas9	negative selection	10240820
140504666	140504689	X	-	28162770	P31FUJ	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.7473753772441372	[79]	[27]	-8	hSpCas9	negative selection	10240821
140504583	140504606	X	-	28162770	P31FUJ	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.7853451422958808	[157]	[319]	8	hSpCas9	negative selection	10240822
140504487	140504510	X	-	28162770	P31FUJ	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.5611192745639035	[446]	[774]	6	hSpCas9	negative selection	10240823
140503835	140503858	X	-	28162770	P31FUJ	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.38753462640866276	[375]	[577]	4	hSpCas9	negative selection	10240824
140504775	140504798	X	-	28162770	TF1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10410181
140503766	140503789	X	-	28162770	TF1	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10410182
140504999	140505022	X	+	28162770	TF1	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10410183
140504964	140504987	X	-	28162770	TF1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	NaN	[NaN]	[371]	1	hSpCas9	negative selection	10410184
140504848	140504871	X	+	28162770	TF1	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	NaN	[NaN]	[461]	1	hSpCas9	negative selection	10410185
140504821	140504844	X	+	28162770	TF1	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	NaN	[NaN]	[206]	1	hSpCas9	negative selection	10410186
140504666	140504689	X	-	28162770	TF1	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10410187
140504583	140504606	X	-	28162770	TF1	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10410188
140504487	140504510	X	-	28162770	TF1	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	NaN	[NaN]	[389]	1	hSpCas9	negative selection	10410189
140503835	140503858	X	-	28162770	TF1	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	NaN	[NaN]	[525]	1	hSpCas9	negative selection	10410190
140504775	140504798	X	-	28162770	SKM1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.3833172099555011	[84]	[195]	4	hSpCas9	negative selection	10579547
140503766	140503789	X	-	28162770	SKM1	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.7205255363787542	[45]	[133]	7	hSpCas9	negative selection	10579548
140504999	140505022	X	+	28162770	SKM1	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.712775045530934	[38]	[112]	7	hSpCas9	negative selection	10579549
140504964	140504987	X	-	28162770	SKM1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.13301084720468426	[113]	[220]	1	hSpCas9	negative selection	10579550
140504848	140504871	X	+	28162770	SKM1	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.1426652288657138	[61]	[241]	9	hSpCas9	negative selection	10579551
140504821	140504844	X	+	28162770	SKM1	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	-0.49015813426956056	[57]	[72]	-4	hSpCas9	negative selection	10579552
140504666	140504689	X	-	28162770	SKM1	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	0.6973724610715741	[14]	[42]	6	hSpCas9	negative selection	10579553
140504583	140504606	X	-	28162770	SKM1	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.7766357395962273	[34]	[105]	7	hSpCas9	negative selection	10579554
140504487	140504510	X	-	28162770	SKM1	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.7789023465681723	[89]	[272]	7	hSpCas9	negative selection	10579555
140503835	140503858	X	-	28162770	SKM1	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.7978945928085379	[67]	[208]	7	hSpCas9	negative selection	10579556
140504775	140504798	X	-	28162770	SKM1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.3833172099555011	[84]	[195]	4	hSpCas9	negative selection	10748913
140503766	140503789	X	-	28162770	SKM1	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.7205255363787542	[45]	[133]	7	hSpCas9	negative selection	10748914
140504999	140505022	X	+	28162770	SKM1	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.712775045530934	[38]	[112]	7	hSpCas9	negative selection	10748915
140504964	140504987	X	-	28162770	SKM1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.13301084720468426	[113]	[220]	1	hSpCas9	negative selection	10748916
140504848	140504871	X	+	28162770	SKM1	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.1426652288657138	[61]	[241]	9	hSpCas9	negative selection	10748917
140504821	140504844	X	+	28162770	SKM1	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	-0.49015813426956056	[57]	[72]	-4	hSpCas9	negative selection	10748918
140504666	140504689	X	-	28162770	SKM1	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	0.6973724610715741	[14]	[42]	6	hSpCas9	negative selection	10748919
140504583	140504606	X	-	28162770	SKM1	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.7766357395962273	[34]	[105]	7	hSpCas9	negative selection	10748920
140504487	140504510	X	-	28162770	SKM1	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.7789023465681723	[89]	[272]	7	hSpCas9	negative selection	10748921
140503835	140503858	X	-	28162770	SKM1	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.7978945928085379	[67]	[208]	7	hSpCas9	negative selection	10748922
140504775	140504798	X	-	28162770	PL21	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	-0.12178848039804224	[314]	[125]	-1	hSpCas9	negative selection	10918279
140503766	140503789	X	-	28162770	PL21	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-0.06763271035113688	[182]	[75]	0	hSpCas9	negative selection	10918280
140504999	140505022	X	+	28162770	PL21	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	-0.8587540745642486	[149]	[35]	-5	hSpCas9	negative selection	10918281
140504964	140504987	X	-	28162770	PL21	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.15344637904127878	[470]	[227]	1	hSpCas9	negative selection	10918282
140504848	140504871	X	+	28162770	PL21	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.898312725658467	[195]	[317]	9	hSpCas9	negative selection	10918283
140504821	140504844	X	+	28162770	PL21	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.49104081375605796	[187]	[114]	4	hSpCas9	negative selection	10918284
140504666	140504689	X	-	28162770	PL21	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.0222528068471282	[41]	[8]	-6	hSpCas9	negative selection	10918285
140504583	140504606	X	-	28162770	PL21	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.477673590018229	[131]	[79]	4	hSpCas9	negative selection	10918286
140504487	140504510	X	-	28162770	PL21	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.4211664938015386	[301]	[175]	3	hSpCas9	negative selection	10918287
140503835	140503858	X	-	28162770	PL21	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.8171957449203296	[325]	[249]	7	hSpCas9	negative selection	10918288
140504775	140504798	X	-	28162770	P31FUJ	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	-0.1843036867231887	[233]	[241]	-2	hSpCas9	negative selection	11087645
140503766	140503789	X	-	28162770	P31FUJ	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-0.17204817333528252	[278]	[290]	-2	hSpCas9	negative selection	11087646
140504999	140505022	X	+	28162770	P31FUJ	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.01833011236312343	[141]	[168]	0	hSpCas9	negative selection	11087647
140504964	140504987	X	-	28162770	P31FUJ	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.12166641854691884	[376]	[481]	1	hSpCas9	negative selection	11087648
140504848	140504871	X	+	28162770	P31FUJ	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.4999755927883942	[206]	[343]	5	hSpCas9	negative selection	11087649
140504821	140504844	X	+	28162770	P31FUJ	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.033843454971794085	[132]	[159]	0	hSpCas9	negative selection	11087650
140504666	140504689	X	-	28162770	P31FUJ	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.7473753772441372	[79]	[27]	-8	hSpCas9	negative selection	11087651
140504583	140504606	X	-	28162770	P31FUJ	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.7853451422958808	[157]	[319]	8	hSpCas9	negative selection	11087652
140504487	140504510	X	-	28162770	P31FUJ	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.5611192745639035	[446]	[774]	6	hSpCas9	negative selection	11087653
140503835	140503858	X	-	28162770	P31FUJ	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.38753462640866276	[375]	[577]	4	hSpCas9	negative selection	11087654
140504775	140504798	X	-	28162770	OCIAML5	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.44875249742926704	[178]	[440]	4	hSpCas9	negative selection	11257011
140503766	140503789	X	-	28162770	OCIAML5	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.017146821600648843	[149]	[273]	0	hSpCas9	negative selection	11257012
140504999	140505022	X	+	28162770	OCIAML5	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	1.0824803676473869	[61]	[236]	8	hSpCas9	negative selection	11257013
140504964	140504987	X	-	28162770	OCIAML5	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.7657605637627857	[216]	[665]	6	hSpCas9	negative selection	11257014
140504848	140504871	X	+	28162770	OCIAML5	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.7935026945613113	[100]	[315]	7	hSpCas9	negative selection	11257015
140504821	140504844	X	+	28162770	OCIAML5	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.46182420495794696	[71]	[178]	4	hSpCas9	negative selection	11257016
140504666	140504689	X	-	28162770	OCIAML5	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-2.597493743778399	[56]	[16]	-8	hSpCas9	negative selection	11257017
140504583	140504606	X	-	28162770	OCIAML5	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.0778549933998625	[57]	[220]	8	hSpCas9	negative selection	11257018
140504487	140504510	X	-	28162770	OCIAML5	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.4349058896265523	[258]	[631]	4	hSpCas9	negative selection	11257019
140503835	140503858	X	-	28162770	OCIAML5	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.6430992595065133	[231]	[653]	5	hSpCas9	negative selection	11257020
140504775	140504798	X	-	28162770	EOL1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.113631517067873	[506]	[288]	1	hSpCas9	negative selection	11426377
140503766	140503789	X	-	28162770	EOL1	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.6913485952775037	[267]	[227]	6	hSpCas9	negative selection	11426378
140504999	140505022	X	+	28162770	EOL1	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.6082151395766916	[192]	[154]	5	hSpCas9	negative selection	11426379
140504964	140504987	X	-	28162770	EOL1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.3503486123265518	[867]	[582]	3	hSpCas9	negative selection	11426380
140504848	140504871	X	+	28162770	EOL1	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.8090705541505985	[415]	[383]	7	hSpCas9	negative selection	11426381
140504821	140504844	X	+	28162770	EOL1	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.3508125262726325	[255]	[171]	3	hSpCas9	negative selection	11426382
140504666	140504689	X	-	28162770	EOL1	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.284905594058415	[73]	[15]	-7	hSpCas9	negative selection	11426383
140504583	140504606	X	-	28162770	EOL1	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.0445475476811645	[195]	[212]	8	hSpCas9	negative selection	11426384
140504487	140504510	X	-	28162770	EOL1	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	-0.1846156719171992	[493]	[228]	-1	hSpCas9	negative selection	11426385
140503835	140503858	X	-	28162770	EOL1	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.7787766318369993	[384]	[347]	7	hSpCas9	negative selection	11426386
140504775	140504798	X	-	28162770	MOLM13	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.2355441797819253	[399]	[680]	8	hSpCas9	negative selection	11595743
140503766	140503789	X	-	28162770	MOLM13	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-0.272142515669411	[313]	[187]	-2	hSpCas9	negative selection	11595744
140504999	140505022	X	+	28162770	MOLM13	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	1.826149689118166	[148]	[381]	9	hSpCas9	negative selection	11595745
140504964	140504987	X	-	28162770	MOLM13	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	1.0304592702232465	[605]	[894]	7	hSpCas9	negative selection	11595746
140504848	140504871	X	+	28162770	MOLM13	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	1.3658547473736136	[226]	[422]	9	hSpCas9	negative selection	11595747
140504821	140504844	X	+	28162770	MOLM13	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	1.823048005998575	[205]	[526]	9	hSpCas9	negative selection	11595748
140504666	140504689	X	-	28162770	MOLM13	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.8920065635418042	[76]	[14]	-7	hSpCas9	negative selection	11595749
140504583	140504606	X	-	28162770	MOLM13	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.8540141889081839	[188]	[246]	6	hSpCas9	negative selection	11595750
140504487	140504510	X	-	28162770	MOLM13	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	-0.011051169601578259	[576]	[413]	0	hSpCas9	negative selection	11595751
140503835	140503858	X	-	28162770	MOLM13	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.7217500831204369	[446]	[532]	5	hSpCas9	negative selection	11595752
140504775	140504798	X	-	28162770	HEL	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.09925296725536	[359]	[493]	8	hSpCas9	negative selection	11765109
140503766	140503789	X	-	28162770	HEL	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.5933508050381935	[207]	[200]	5	hSpCas9	negative selection	11765110
140504999	140505022	X	+	28162770	HEL	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	-0.07663270215111095	[162]	[98]	0	hSpCas9	negative selection	11765111
140504964	140504987	X	-	28162770	HEL	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.6878267215288951	[566]	[584]	6	hSpCas9	negative selection	11765112
140504848	140504871	X	+	28162770	HEL	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.9457035229151243	[290]	[358]	7	hSpCas9	negative selection	11765113
140504821	140504844	X	+	28162770	HEL	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.2445751512859094	[169]	[128]	2	hSpCas9	negative selection	11765114
140504666	140504689	X	-	28162770	HEL	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-2.1646160900572475	[62]	[8]	-8	hSpCas9	negative selection	11765115
140504583	140504606	X	-	28162770	HEL	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.672486175394409	[143]	[293]	9	hSpCas9	negative selection	11765116
140504487	140504510	X	-	28162770	HEL	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.4220507168761579	[422]	[362]	3	hSpCas9	negative selection	11765117
140503835	140503858	X	-	28162770	HEL	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.22633060098809865	[350]	[262]	1	hSpCas9	negative selection	11765118
140504775	140504798	X	-	28162770	MV411	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.0760480328804305	[307]	[546]	8	hSpCas9	negative selection	11934475
140503766	140503789	X	-	28162770	MV411	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.2990996706052681	[191]	[198]	2	hSpCas9	negative selection	11934476
140504999	140505022	X	+	28162770	MV411	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	-0.385353475028996	[137]	[88]	-3	hSpCas9	negative selection	11934477
140504964	140504987	X	-	28162770	MV411	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.8828898219576247	[364]	[566]	7	hSpCas9	negative selection	11934478
140504848	140504871	X	+	28162770	MV411	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.12304668854558526	[229]	[210]	1	hSpCas9	negative selection	11934479
140504821	140504844	X	+	28162770	MV411	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	-0.08407659293378505	[150]	[119]	0	hSpCas9	negative selection	11934480
140504666	140504689	X	-	28162770	MV411	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	0.5418849092480307	[52]	[64]	5	hSpCas9	negative selection	11934481
140504583	140504606	X	-	28162770	MV411	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	-0.18552185649333103	[134]	[99]	-1	hSpCas9	negative selection	11934482
140504487	140504510	X	-	28162770	MV411	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.7591791328293708	[356]	[508]	7	hSpCas9	negative selection	11934483
140503835	140503858	X	-	28162770	MV411	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.84259581860982	[328]	[496]	7	hSpCas9	negative selection	11934484
140504775	140504798	X	-	28162770	MONOMAC1	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	1.2682554229989862	[133]	[369]	9	hSpCas9	negative selection	12103841
140503766	140503789	X	-	28162770	MONOMAC1	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.39143159716313813	[136]	[205]	4	hSpCas9	negative selection	12103842
140504999	140505022	X	+	28162770	MONOMAC1	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	-0.008591757646443487	[85]	[97]	0	hSpCas9	negative selection	12103843
140504964	140504987	X	-	28162770	MONOMAC1	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.026927994095647723	[261]	[305]	0	hSpCas9	negative selection	12103844
140504848	140504871	X	+	28162770	MONOMAC1	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.07859759555387369	[132]	[160]	0	hSpCas9	negative selection	12103845
140504821	140504844	X	+	28162770	MONOMAC1	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	0.19528057571920646	[95]	[125]	2	hSpCas9	negative selection	12103846
140504666	140504689	X	-	28162770	MONOMAC1	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	1.9107664424749609	[28]	[124]	9	hSpCas9	negative selection	12103847
140504583	140504606	X	-	28162770	MONOMAC1	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	1.1338800310550632	[63]	[160]	8	hSpCas9	negative selection	12103848
140504487	140504510	X	-	28162770	MONOMAC1	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	1.1501285393268317	[203]	[518]	8	hSpCas9	negative selection	12103849
140503835	140503858	X	-	28162770	MONOMAC1	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.2810104497450906	[223]	[311]	3	hSpCas9	negative selection	12103850
140504775	140504798	X	-	28162770	OCIAML2	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.8595187764501696	[34]	[351]	8	hSpCas9	negative selection	12273207
140503766	140503789	X	-	28162770	OCIAML2	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	-0.4331551198234982	[37]	[155]	-3	hSpCas9	negative selection	12273208
140504999	140505022	X	+	28162770	OCIAML2	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.7694212625907935	[28]	[273]	7	hSpCas9	negative selection	12273209
140504964	140504987	X	-	28162770	OCIAML2	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	0.6937569926587213	[86]	[779]	6	hSpCas9	negative selection	12273210
140504848	140504871	X	+	28162770	OCIAML2	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	0.09571699731164793	[38]	[230]	0	hSpCas9	negative selection	12273211
140504821	140504844	X	+	28162770	OCIAML2	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	1.2677223091950076	[25]	[346]	9	hSpCas9	negative selection	12273212
140504666	140504689	X	-	28162770	OCIAML2	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-0.5164335148552861	[7]	[30]	-4	hSpCas9	negative selection	12273213
140504583	140504606	X	-	28162770	OCIAML2	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	0.229809892898931	[23]	[155]	2	hSpCas9	negative selection	12273214
140504487	140504510	X	-	28162770	OCIAML2	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.5166141673333864	[70]	[562]	5	hSpCas9	negative selection	12273215
140503835	140503858	X	-	28162770	OCIAML2	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.5649940844885601	[49]	[409]	5	hSpCas9	negative selection	12273216
140504775	140504798	X	-	28162770	OCIAML3	viability	AGGGACACCCACACAAGCGGCGG	SOX3	ENSG00000134595	0.8045417361661116	[65]	[347]	7	hSpCas9	negative selection	12442573
140503766	140503789	X	-	28162770	OCIAML3	viability	GGCGTGCACCAGCACTACCAGGG	SOX3	ENSG00000134595	0.6999060783936026	[51]	[254]	6	hSpCas9	negative selection	12442574
140504999	140505022	X	+	28162770	OCIAML3	viability	GCCAAATCAGCAGGAACCCGCGG	SOX3	ENSG00000134595	0.03217752312350575	[22]	[70]	0	hSpCas9	negative selection	12442575
140504964	140504987	X	-	28162770	OCIAML3	viability	GATAAGCCTACCCTTCCCGCCGG	SOX3	ENSG00000134595	-0.46091940706222234	[118]	[260]	-4	hSpCas9	negative selection	12442576
140504848	140504871	X	+	28162770	OCIAML3	viability	AAGAAGGTGCGCCAGCGTGGCGG	SOX3	ENSG00000134595	-0.09650798085334639	[67]	[191]	0	hSpCas9	negative selection	12442577
140504821	140504844	X	+	28162770	OCIAML3	viability	CAGAAGGCTGTACATTGCCGGGG	SOX3	ENSG00000134595	1.305828197750405	[40]	[305]	9	hSpCas9	negative selection	12442578
140504666	140504689	X	-	28162770	OCIAML3	viability	GGTGGTGCGAGCGGAGGTGGCGG	SOX3	ENSG00000134595	-1.7544723125174093	[18]	[16]	-8	hSpCas9	negative selection	12442579
140504583	140504606	X	-	28162770	OCIAML3	viability	GCAGCGGCGCAAAATGGCCCTGG	SOX3	ENSG00000134595	-0.5555334925095274	[36]	[75]	-4	hSpCas9	negative selection	12442580
140504487	140504510	X	-	28162770	OCIAML3	viability	GAAGCGACCATTCATCGACGAGG	SOX3	ENSG00000134595	0.8779149224963307	[114]	[637]	7	hSpCas9	negative selection	12442581
140503835	140503858	X	-	28162770	OCIAML3	viability	AGCATGTACCTGCCACCCGGCGG	SOX3	ENSG00000134595	0.147074062314275	[104]	[350]	1	hSpCas9	negative selection	12442582