Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23013
• Symbol: SPEN
• Description: spen family transcriptional repressor

DataSource: http://genomecrispr.dkfz.de/#!/results/SPEN

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15920933	15920956	1	+	26472758	Jiyoye	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	1.0218852256210815	[31]	[48]	6	hSpCas9	negative selection	155085
15932070	15932093	1	+	26472758	Jiyoye	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.0098756492106187	[477]	[178]	-6	hSpCas9	negative selection	155086
15929997	15930020	1	+	26472758	Jiyoye	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-2.540357198599991	[53]	[6]	-9	hSpCas9	negative selection	155087
15936217	15936240	1	-	26472758	Jiyoye	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.6136262589732997	[77]	[89]	4	hSpCas9	negative selection	155088
15872852	15872875	1	+	26472758	Jiyoye	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.762749619936439	[98]	[10]	-9	hSpCas9	negative selection	155089
15872878	15872901	1	-	26472758	Jiyoye	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	1.8666070001431707	[23]	[65]	8	hSpCas9	negative selection	155090
15872939	15872962	1	+	26472758	Jiyoye	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.3890280347956142	[79]	[78]	3	hSpCas9	negative selection	155091
15873039	15873062	1	+	26472758	Jiyoye	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.7055166560756198	[73]	[90]	5	hSpCas9	negative selection	155092
15928378	15928401	1	+	26472758	Jiyoye	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.3800952945083983	[106]	[61]	-3	hSpCas9	negative selection	155093
15930869	15930892	1	+	26472758	Jiyoye	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-3.137145134717937	[34]	[2]	-9	hSpCas9	negative selection	155094
15920933	15920956	1	+	26472758	KBM7	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.25518632642812267	[168,173]	[86,50]	-2	hSpCas9	negative selection	346203
15932070	15932093	1	+	26472758	KBM7	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.2689521972678903	[1171,1420]	[158,343]	-7	hSpCas9	negative selection	346204
15929997	15930020	1	+	26472758	KBM7	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.6606448373611098	[157,102]	[34,40]	-5	hSpCas9	negative selection	346205
15936217	15936240	1	-	26472758	KBM7	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.1839742562771642	[388,348]	[225,170]	1	hSpCas9	negative selection	346206
15872852	15872875	1	+	26472758	KBM7	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.8675457444284795	[344,371]	[45,2]	-9	hSpCas9	negative selection	346207
15872878	15872901	1	-	26472758	KBM7	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.2869106794337739	[229,204]	[121,126]	3	hSpCas9	negative selection	346208
15872939	15872962	1	+	26472758	KBM7	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-1.2607230430264773	[492,327]	[54,100]	-7	hSpCas9	negative selection	346209
15873039	15873062	1	+	26472758	KBM7	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.48778804175900514	[539,219]	[149,97]	-4	hSpCas9	negative selection	346210
15928378	15928401	1	+	26472758	KBM7	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.7545272330143807	[389,356]	[129,80]	-6	hSpCas9	negative selection	346211
15930869	15930892	1	+	26472758	KBM7	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-1.4748452978790119	[120,140]	[32,12]	-8	hSpCas9	negative selection	346212
15920933	15920956	1	+	26472758	Raji	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.1867995690308586	[102]	[20]	-1	hSpCas9	negative selection	537321
15932070	15932093	1	+	26472758	Raji	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.8029379656351925	[841]	[55]	-8	hSpCas9	negative selection	537322
15929997	15930020	1	+	26472758	Raji	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.44281354718688015	[81]	[13]	-4	hSpCas9	negative selection	537323
15936217	15936240	1	-	26472758	Raji	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.14627254876719434	[182]	[46]	1	hSpCas9	negative selection	537324
15872852	15872875	1	+	26472758	Raji	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.6896294424625458	[138]	[4]	-9	hSpCas9	negative selection	537325
15872878	15872901	1	-	26472758	Raji	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.19665087347068688	[93]	[24]	1	hSpCas9	negative selection	537326
15872939	15872962	1	+	26472758	Raji	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.4627147885281757	[221]	[70]	4	hSpCas9	negative selection	537327
15873039	15873062	1	+	26472758	Raji	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-1.2217400609179667	[200]	[19]	-7	hSpCas9	negative selection	537328
15928378	15928401	1	+	26472758	Raji	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-1.0256418832571836	[192]	[21]	-6	hSpCas9	negative selection	537329
15930869	15930892	1	+	26472758	Raji	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-1.2145445595137625	[39]	[3]	-7	hSpCas9	negative selection	537330
15920933	15920956	1	+	26472758	K562	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-6.310170124011191	[187]	[1]	-9	hSpCas9	negative selection	728439
15932070	15932093	1	+	26472758	K562	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.4801276072456915	[1040]	[314]	-6	hSpCas9	negative selection	728440
15929997	15930020	1	+	26472758	K562	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.14604074889173058	[96]	[73]	-1	hSpCas9	negative selection	728441
15936217	15936240	1	-	26472758	K562	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	-0.1779607469535649	[393]	[293]	-1	hSpCas9	negative selection	728442
15872852	15872875	1	+	26472758	K562	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-5.154752366153375	[210]	[4]	-9	hSpCas9	negative selection	728443
15872878	15872901	1	-	26472758	K562	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	-0.7422844497200953	[215]	[108]	-4	hSpCas9	negative selection	728444
15872939	15872962	1	+	26472758	K562	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-1.1567864984328275	[345]	[130]	-6	hSpCas9	negative selection	728445
15873039	15873062	1	+	26472758	K562	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.5711567011961256	[263]	[149]	-4	hSpCas9	negative selection	728446
15928378	15928401	1	+	26472758	K562	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.8942348121195833	[250]	[113]	-5	hSpCas9	negative selection	728447
15930869	15930892	1	+	26472758	K562	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.938803096389323	[108]	[47]	-5	hSpCas9	negative selection	728448
15848063	15848086	1	+	26627737	DLD1	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.9951048113586913	[2142]	[1024,1693,1306]	8	hSpCas9	negative selection	767163
15873087	15873110	1	-	26627737	DLD1	viability	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	767175
15876239	15876262	1	+	26627737	DLD1	viability	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.20813874219691608	[1189]	[461,525,321]	2	hSpCas9	negative selection	767176
15909355	15909378	1	-	26627737	DLD1	viability	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.7028650821434927	[789]	[445,571,222]	7	hSpCas9	negative selection	767194
15911198	15911221	1	+	26627737	DLD1	viability	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.33485303195767246	[260]	[68,159,84]	3	hSpCas9	negative selection	767195
15916243	15916266	1	-	26627737	DLD1	viability	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.8331369588826051	[460]	[170,356,247]	7	hSpCas9	negative selection	767197
15848063	15848086	1	+	26627737	GBM cells	viability after 5 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.31125871656248183	[1253]	[673,409]	-5	hSpCas9	negative selection	849478
15873087	15873110	1	-	26627737	GBM cells	viability after 5 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	849490
15876239	15876262	1	+	26627737	GBM cells	viability after 5 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.14882671406051218	[552]	[283,250]	-2	hSpCas9	negative selection	849491
15909355	15909378	1	-	26627737	GBM cells	viability after 5 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.6654625805554037	[250]	[201,224]	8	hSpCas9	negative selection	849509
15911198	15911221	1	+	26627737	GBM cells	viability after 5 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.05576213460482404	[93]	[58,37]	-1	hSpCas9	negative selection	849510
15916243	15916266	1	-	26627737	GBM cells	viability after 5 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.13671003484503563	[245]	[80,158]	-2	hSpCas9	negative selection	849512
15848063	15848086	1	+	26627737	GBM cells	viability after 13 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.32883297986765614	[1253]	[592,499]	-4	hSpCas9	negative selection	931793
15873087	15873110	1	-	26627737	GBM cells	viability after 13 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	931805
15876239	15876262	1	+	26627737	GBM cells	viability after 13 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.14860687472595036	[552]	[316,232]	-2	hSpCas9	negative selection	931806
15909355	15909378	1	-	26627737	GBM cells	viability after 13 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.24338595059679377	[250]	[174,149]	3	hSpCas9	negative selection	931824
15911198	15911221	1	+	26627737	GBM cells	viability after 13 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.4469131734875943	[93]	[79,60]	5	hSpCas9	negative selection	931825
15916243	15916266	1	-	26627737	GBM cells	viability after 13 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.5673800942338367	[245]	[99,81]	-6	hSpCas9	negative selection	931827
15848063	15848086	1	+	26627737	GBM cells	viability after 21 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.24874615182773807	[1253]	[587,559]	-2	hSpCas9	negative selection	1014108
15873087	15873110	1	-	26627737	GBM cells	viability after 21 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1014120
15876239	15876262	1	+	26627737	GBM cells	viability after 21 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.13603293790035087	[552]	[263,281]	-1	hSpCas9	negative selection	1014121
15909355	15909378	1	-	26627737	GBM cells	viability after 21 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.46779061454324367	[250]	[209,168]	5	hSpCas9	negative selection	1014139
15911198	15911221	1	+	26627737	GBM cells	viability after 21 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.7970487082413942	[93]	[94,82]	7	hSpCas9	negative selection	1014140
15916243	15916266	1	-	26627737	GBM cells	viability after 21 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.34224600750725254	[245]	[118,92]	-3	hSpCas9	negative selection	1014142
15848063	15848086	1	+	26627737	RPE1	viability after 9 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.7823669940570446	[4762]	[666,1124]	-5	hSpCas9	negative selection	1096423
15873087	15873110	1	-	26627737	RPE1	viability after 9 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1096435
15876239	15876262	1	+	26627737	RPE1	viability after 9 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.5025007871500589	[1255]	[215,356]	-4	hSpCas9	negative selection	1096436
15909355	15909378	1	-	26627737	RPE1	viability after 9 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.36108484665048113	[662]	[89,253]	-3	hSpCas9	negative selection	1096454
15911198	15911221	1	+	26627737	RPE1	viability after 9 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.7231809007137957	[425]	[68,95]	-5	hSpCas9	negative selection	1096455
15916243	15916266	1	-	26627737	RPE1	viability after 9 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-1.3167593122033825	[1312]	[140,195]	-7	hSpCas9	negative selection	1096457
15848063	15848086	1	+	26627737	RPE1	viability after 12 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.7383531748583259	[4762]	[700,836]	-5	hSpCas9	negative selection	1178738
15873087	15873110	1	-	26627737	RPE1	viability after 12 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1178750
15876239	15876262	1	+	26627737	RPE1	viability after 12 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.4264731997401792	[1255]	[304,193]	-3	hSpCas9	negative selection	1178751
15909355	15909378	1	-	26627737	RPE1	viability after 12 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.593063017009876	[662]	[69,168]	-4	hSpCas9	negative selection	1178769
15911198	15911221	1	+	26627737	RPE1	viability after 12 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.4306628249590707	[425]	[47,123]	-3	hSpCas9	negative selection	1178770
15916243	15916266	1	-	26627737	RPE1	viability after 12 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-1.8084152639911975	[1312]	[107,92]	-8	hSpCas9	negative selection	1178772
15848063	15848086	1	+	26627737	RPE1	viability after 15 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.6850527864649856	[4762]	[948,730]	-4	hSpCas9	negative selection	1261053
15873087	15873110	1	-	26627737	RPE1	viability after 15 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1261065
15876239	15876262	1	+	26627737	RPE1	viability after 15 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.25666371963853224	[1255]	[387,209]	-2	hSpCas9	negative selection	1261066
15909355	15909378	1	-	26627737	RPE1	viability after 15 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.6514516925102442	[662]	[124,113]	-4	hSpCas9	negative selection	1261084
15911198	15911221	1	+	26627737	RPE1	viability after 15 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.8059981858407037	[425]	[44,91]	-5	hSpCas9	negative selection	1261085
15916243	15916266	1	-	26627737	RPE1	viability after 15 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-1.3329730642681863	[1312]	[122,170]	-7	hSpCas9	negative selection	1261087
15848063	15848086	1	+	26627737	RPE1	viability after 18 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.5931565809948789	[4762]	[722,989]	-4	hSpCas9	negative selection	1343368
15873087	15873110	1	-	26627737	RPE1	viability after 18 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1343380
15876239	15876262	1	+	26627737	RPE1	viability after 18 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.10009027623660138	[1255]	[395,230]	0	hSpCas9	negative selection	1343381
15909355	15909378	1	-	26627737	RPE1	viability after 18 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-1.6198031917431561	[662]	[49,66]	-7	hSpCas9	negative selection	1343399
15911198	15911221	1	+	26627737	RPE1	viability after 18 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.7934135995924312	[425]	[75,55]	-5	hSpCas9	negative selection	1343400
15916243	15916266	1	-	26627737	RPE1	viability after 18 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-1.4258843683524929	[1312]	[142,119]	-7	hSpCas9	negative selection	1343402
15848063	15848086	1	+	26627737	HeLa	viability after 8 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.1690523444695664	[2295]	[1234,1459,727]	1	hSpCas9	negative selection	1425683
15873087	15873110	1	-	26627737	HeLa	viability after 8 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1425695
15876239	15876262	1	+	26627737	HeLa	viability after 8 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.5862465661735405	[1424]	[380,378,467]	-5	hSpCas9	negative selection	1425696
15909355	15909378	1	-	26627737	HeLa	viability after 8 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.4409830261908072	[647]	[399,248,494]	4	hSpCas9	negative selection	1425714
15911198	15911221	1	+	26627737	HeLa	viability after 8 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.1724454053068203	[105]	[83,41,37]	1	hSpCas9	negative selection	1425715
15916243	15916266	1	-	26627737	HeLa	viability after 8 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.11600489875793601	[275]	[107,123,151]	1	hSpCas9	negative selection	1425717
15848063	15848086	1	+	26627737	HeLa	viability after 12 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.002746086370242651	[2295]	[1166,858,841]	0	hSpCas9	negative selection	1507998
15873087	15873110	1	-	26627737	HeLa	viability after 12 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1508010
15876239	15876262	1	+	26627737	HeLa	viability after 12 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.6994688456884295	[1424]	[463,219,421]	-6	hSpCas9	negative selection	1508011
15909355	15909378	1	-	26627737	HeLa	viability after 12 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.8652004084087721	[647]	[188,139,113]	-7	hSpCas9	negative selection	1508029
15911198	15911221	1	+	26627737	HeLa	viability after 12 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.44458944930497846	[105]	[64,87,22]	4	hSpCas9	negative selection	1508030
15916243	15916266	1	-	26627737	HeLa	viability after 12 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.13840696231318506	[275]	[142,84,85]	-1	hSpCas9	negative selection	1508032
15848063	15848086	1	+	26627737	HeLa	viability after 15 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.17644285662786663	[2295]	[1610,696,836]	1	hSpCas9	negative selection	1590313
15873087	15873110	1	-	26627737	HeLa	viability after 15 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1590325
15876239	15876262	1	+	26627737	HeLa	viability after 15 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.9379667580935178	[1424]	[461,157,284]	-7	hSpCas9	negative selection	1590326
15909355	15909378	1	-	26627737	HeLa	viability after 15 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.2973454587588573	[647]	[339,263,371]	2	hSpCas9	negative selection	1590344
15911198	15911221	1	+	26627737	HeLa	viability after 15 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	1.0557157726917086	[105]	[70,124,71]	7	hSpCas9	negative selection	1590345
15916243	15916266	1	-	26627737	HeLa	viability after 15 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.1101327072106108	[275]	[232,60,63]	1	hSpCas9	negative selection	1590347
15848063	15848086	1	+	26627737	HeLa	viability after 18 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.1933105813303544	[2295]	[1109,570,836]	1	hSpCas9	negative selection	1672628
15873087	15873110	1	-	26627737	HeLa	viability after 18 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1672640
15876239	15876262	1	+	26627737	HeLa	viability after 18 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.9113910698392711	[1424]	[319,131,284]	-7	hSpCas9	negative selection	1672641
15909355	15909378	1	-	26627737	HeLa	viability after 18 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.30417454588787773	[647]	[229,219,371]	2	hSpCas9	negative selection	1672659
15911198	15911221	1	+	26627737	HeLa	viability after 18 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	1.094534782456567	[105]	[47,108,71]	7	hSpCas9	negative selection	1672660
15916243	15916266	1	-	26627737	HeLa	viability after 18 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.10066423463370039	[275]	[151,53,63]	0	hSpCas9	negative selection	1672662
15848063	15848086	1	+	26627737	HCT116	viability after 6 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.1325556910818113	[4455]	[1066,602]	0	hSpCas9	negative selection	1754943
15873087	15873110	1	-	26627737	HCT116	viability after 6 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1754955
15876239	15876262	1	+	26627737	HCT116	viability after 6 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.8702575974158053	[1314]	[471,325]	5	hSpCas9	negative selection	1754956
15909355	15909378	1	-	26627737	HCT116	viability after 6 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.42977889286658666	[890]	[190,55]	-2	hSpCas9	negative selection	1754974
15911198	15911221	1	+	26627737	HCT116	viability after 6 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.06480752674002965	[219]	[34,31]	0	hSpCas9	negative selection	1754975
15916243	15916266	1	-	26627737	HCT116	viability after 6 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.699943805622839	[602]	[211,121]	4	hSpCas9	negative selection	1754977
15848063	15848086	1	+	26627737	HCT116	viability after 8 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.279959804982584	[1408]	[895,808,1119]	3	hSpCas9	negative selection	1837258
15873087	15873110	1	-	26627737	HCT116	viability after 8 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1837270
15876239	15876262	1	+	26627737	HCT116	viability after 8 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.4732529823719156	[497]	[361,357,421]	5	hSpCas9	negative selection	1837271
15909355	15909378	1	-	26627737	HCT116	viability after 8 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.20354289694166128	[373]	[106,198,228]	-2	hSpCas9	negative selection	1837289
15911198	15911221	1	+	26627737	HCT116	viability after 8 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.651943869369636	[94]	[74,119,51]	6	hSpCas9	negative selection	1837290
15916243	15916266	1	-	26627737	HCT116	viability after 8 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.6697827146937849	[376]	[83,182,123]	-7	hSpCas9	negative selection	1837292
15848063	15848086	1	+	26627737	HCT116	viability after 9 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.08146724344358613	[4455]	[1101,1382]	0	hSpCas9	negative selection	1919573
15873087	15873110	1	-	26627737	HCT116	viability after 9 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1919585
15876239	15876262	1	+	26627737	HCT116	viability after 9 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.30785027134088105	[1314]	[367,216]	-2	hSpCas9	negative selection	1919586
15909355	15909378	1	-	26627737	HCT116	viability after 9 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-1.025483156265366	[890]	[98,130]	-6	hSpCas9	negative selection	1919604
15911198	15911221	1	+	26627737	HCT116	viability after 9 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.9274994056253066	[219]	[99,120]	6	hSpCas9	negative selection	1919605
15916243	15916266	1	-	26627737	HCT116	viability after 9 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.3389778708418414	[602]	[39,332]	2	hSpCas9	negative selection	1919607
15848063	15848086	1	+	26627737	HCT116	viability after 12 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.23167311388169542	[1408]	[884,910,811]	2	hSpCas9	negative selection	2001888
15873087	15873110	1	-	26627737	HCT116	viability after 12 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2001900
15876239	15876262	1	+	26627737	HCT116	viability after 12 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.34346493801638656	[497]	[328,395,272]	3	hSpCas9	negative selection	2001901
15909355	15909378	1	-	26627737	HCT116	viability after 12 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.21975484096904957	[373]	[261,197,222]	2	hSpCas9	negative selection	2001919
15911198	15911221	1	+	26627737	HCT116	viability after 12 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.2218952194369701	[94]	[39,87,48]	2	hSpCas9	negative selection	2001920
15916243	15916266	1	-	26627737	HCT116	viability after 12 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.5685010427597381	[376]	[90,193,120]	-6	hSpCas9	negative selection	2001922
15848063	15848086	1	+	26627737	HCT116	viability after 15 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.28041756031225384	[1408]	[1019,875,1055]	3	hSpCas9	negative selection	2084203
15873087	15873110	1	-	26627737	HCT116	viability after 15 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2084215
15876239	15876262	1	+	26627737	HCT116	viability after 15 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.6013869762850041	[497]	[512,583,216]	5	hSpCas9	negative selection	2084216
15909355	15909378	1	-	26627737	HCT116	viability after 15 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.0704651192939077	[373]	[147,195,321]	0	hSpCas9	negative selection	2084234
15911198	15911221	1	+	26627737	HCT116	viability after 15 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.0993870287179126	[94]	[25,93,29]	-1	hSpCas9	negative selection	2084235
15916243	15916266	1	-	26627737	HCT116	viability after 15 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.4737425846342683	[376]	[105,145,208]	-5	hSpCas9	negative selection	2084237
15848063	15848086	1	+	26627737	HCT116	viability after 18 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.7130965098562698	[1408]	[1134,1177,1028]	6	hSpCas9	negative selection	2166518
15873087	15873110	1	-	26627737	HCT116	viability after 18 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2166530
15876239	15876262	1	+	26627737	HCT116	viability after 18 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.47270802893970054	[497]	[355,421,212]	4	hSpCas9	negative selection	2166531
15909355	15909378	1	-	26627737	HCT116	viability after 18 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.8467025075950074	[373]	[421,186,377]	6	hSpCas9	negative selection	2166549
15911198	15911221	1	+	26627737	HCT116	viability after 18 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.7072389001409133	[94]	[56,81,85]	6	hSpCas9	negative selection	2166550
15916243	15916266	1	-	26627737	HCT116	viability after 18 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.8231551835693317	[376]	[147,24,142]	-6	hSpCas9	negative selection	2166552
15848054	15848077	1	+	24336569	HL60	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	0.5995992248316322	[270]	[868]	5	hSpCas9	negative selection	2296991
15848063	15848086	1	+	24336569	HL60	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	1.623877746050986	[112]	[736]	9	hSpCas9	negative selection	2296992
15848072	15848095	1	+	24336569	HL60	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	0.042342100985501396	[278]	[607]	0	hSpCas9	negative selection	2296993
15848077	15848100	1	+	24336569	HL60	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-0.44663129149964387	[833]	[1294]	-4	hSpCas9	negative selection	2296994
15848099	15848122	1	+	24336569	HL60	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	-0.33965724339319114	[1070]	[1790]	-3	hSpCas9	negative selection	2296995
15848107	15848130	1	-	24336569	HL60	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	-0.5891208751826038	[326]	[459]	-5	hSpCas9	negative selection	2296996
15848129	15848152	1	+	24336569	HL60	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	0.07302425620574811	[521]	[1161]	0	hSpCas9	negative selection	2296997
15872812	15872835	1	-	24336569	HL60	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	-0.008671760562967368	[656]	[1381]	0	hSpCas9	negative selection	2296998
15872939	15872962	1	+	24336569	HL60	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.6035408603493214	[505]	[1626]	5	hSpCas9	negative selection	2296999
15872951	15872974	1	-	24336569	HL60	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.6705309996827891	[439]	[584]	-6	hSpCas9	negative selection	2297000
15848054	15848077	1	+	24336569	KBM7	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	0.17322850311899574	[158]	[488]	1	hSpCas9	negative selection	2364168
15848063	15848086	1	+	24336569	KBM7	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.7265551462516977	[90]	[149]	-5	hSpCas9	negative selection	2364169
15848072	15848095	1	+	24336569	KBM7	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	0.08491588427813823	[251]	[728]	0	hSpCas9	negative selection	2364170
15848077	15848100	1	+	24336569	KBM7	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-2.7854488353052664	[727]	[287]	-9	hSpCas9	negative selection	2364171
15848099	15848122	1	+	24336569	KBM7	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	-1.970702443452176	[821]	[571]	-8	hSpCas9	negative selection	2364172
15848107	15848130	1	-	24336569	KBM7	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	1.1913573122746952	[187]	[1170]	8	hSpCas9	negative selection	2364173
15848129	15848152	1	+	24336569	KBM7	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	-0.1687198235534063	[543]	[1319]	-1	hSpCas9	negative selection	2364174
15872812	15872835	1	-	24336569	KBM7	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	0.536000920619087	[485]	[1921]	5	hSpCas9	negative selection	2364175
15872939	15872962	1	+	24336569	KBM7	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-2.06663058784932	[363]	[236]	-8	hSpCas9	negative selection	2364176
15872951	15872974	1	-	24336569	KBM7	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-7.513668387006654	[133]	[1]	-9	hSpCas9	negative selection	2364177
15870062	15870085	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCATGTTGGTCAGGCTGG	SPEN	ENSG00000065526	-0.9950505910624323	[34,30]	[4,1]	-6	dCas9-VP64	positive selection	2385360
15865919	15865942	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTAGTGCAGTGGCATGATCTCAG	SPEN	ENSG00000065526	4.4920303546425915	[16,7]	[10,119]	9	dCas9-VP64	positive selection	2391282
15865075	15865098	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCACTCTGTCGCCCGGG	SPEN	ENSG00000065526	0.8460111869825209	[4,1]	[1,0]	3	dCas9-VP64	positive selection	2391653
15894606	15894629	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGAGGTTGCAGTGAGCCAGGG	SPEN	ENSG00000065526	0.7460875795897541	[229,125]	[97,29]	3	dCas9-VP64	positive selection	2438709
15867473	15867496	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAGGCCTGAGCCACCACGCCTGG	SPEN	ENSG00000065526	3.4338349531393177	[26,8]	[73,8]	9	dCas9-VP64	positive selection	2452784
15872505	15872528	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATGGCGTGAACCCCAG	SPEN	ENSG00000065526	1.2888057383448681	[173,387]	[82,225]	5	dCas9-VP64	positive selection	2465665
15915248	15915271	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTCATCCCAGCACTTTGG	SPEN	ENSG00000065526	0.325764302965428	[325,99]	[107,3]	1	dCas9-VP64	positive selection	2474081
15897637	15897660	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGGGCCACCACGCCTGG	SPEN	ENSG00000065526	2.170805682876019	[0,2]	[0,2]	7	dCas9-VP64	positive selection	2477272
15894613	15894636	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCGCCTCCTGG	SPEN	ENSG00000065526	-0.6462364801057108	[4480,3546]	[594,529]	-3	dCas9-VP64	positive selection	2477589
15870062	15870085	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCATGTTGGTCAGGCTGG	SPEN	ENSG00000065526	-0.9351084987288634	[176,47]	[27,9]	-8	dCas9-VP64	positive selection	2480615
15865919	15865942	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTAGTGCAGTGGCATGATCTCAG	SPEN	ENSG00000065526	0.570567911377349	[309,79]	[100,89]	4	dCas9-VP64	positive selection	2486537
15865075	15865098	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCACTCTGTCGCCCGGG	SPEN	ENSG00000065526	-0.7793844065766207	[74,18]	[14,2]	-7	dCas9-VP64	positive selection	2486908
15894606	15894629	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGAGGTTGCAGTGAGCCAGGG	SPEN	ENSG00000065526	4.721891124701559	[222,102]	[98,2655]	9	dCas9-VP64	positive selection	2533964
15867473	15867496	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAGGCCTGAGCCACCACGCCTGG	SPEN	ENSG00000065526	0.4025668265088169	[39,71]	[26,20]	3	dCas9-VP64	positive selection	2548039
15872505	15872528	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATGGCGTGAACCCCAG	SPEN	ENSG00000065526	0.12656923196241077	[264,270]	[122,69]	1	dCas9-VP64	positive selection	2560920
15915248	15915271	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTCATCCCAGCACTTTGG	SPEN	ENSG00000065526	-0.37865692505671	[209,516]	[60,117]	-4	dCas9-VP64	positive selection	2569336
15897637	15897660	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGGGCCACCACGCCTGG	SPEN	ENSG00000065526	-0.9433721542686317	[3,48]	[3,3]	-8	dCas9-VP64	positive selection	2572527
15894613	15894636	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCGCCTCCTGG	SPEN	ENSG00000065526	0.3752277474843728	[2340,2895]	[765,1428]	3	dCas9-VP64	positive selection	2572844
15873090	15873113	1	+	27260157	DLD1	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.966089463024956	[]	[]	-7	hSpCas9	negative selection	2573580
15876336	15876359	1	+	27260157	DLD1	viability	ATGGGCTCTATTACGCTTCTCGG	SPEN	ENSG00000065526	-0.195404521655641	[]	[]	-1	hSpCas9	negative selection	2574855
15873019	15873042	1	-	27260157	DLD1	viability	CTCTCTACTACGAGATGCTATGG	SPEN	ENSG00000065526	-0.247503457663175	[]	[]	-2	hSpCas9	negative selection	2576760
15876277	15876300	1	+	27260157	DLD1	viability	TCGGACAAGACATTACGATCAGG	SPEN	ENSG00000065526	-0.0282759661351458	[]	[]	0	hSpCas9	negative selection	2577747
15848077	15848100	1	+	27260157	DLD1	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-0.920800171566273	[]	[]	-6	hSpCas9	negative selection	2578859
15872951	15872974	1	-	27260157	DLD1	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.693500172549725	[]	[]	-5	hSpCas9	negative selection	2581036
15848099	15848122	1	+	27260157	DLD1	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	0.576292582542438	[]	[]	8	hSpCas9	negative selection	2581868
15848054	15848077	1	+	27260157	DLD1	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	0.485350260291541	[]	[]	8	hSpCas9	negative selection	2586505
15872955	15872978	1	+	27260157	DLD1	viability	CGCACGGATTATAATGAACCAGG	SPEN	ENSG00000065526	-0.230013886389325	[]	[]	-2	hSpCas9	negative selection	2587014
15873103	15873126	1	+	27260157	DLD1	viability	CACGAGAAGGACGTTATGAGCGG	SPEN	ENSG00000065526	0.951840783146049	[]	[]	9	hSpCas9	negative selection	2604953
15848107	15848130	1	-	27260157	DLD1	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	-0.193351330015654	[]	[]	-1	hSpCas9	negative selection	2605494
15848129	15848152	1	+	27260157	DLD1	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	0.802576485084554	[]	[]	9	hSpCas9	negative selection	2607508
15872812	15872835	1	-	27260157	DLD1	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	1.08783729636523	[]	[]	9	hSpCas9	negative selection	2614575
15873060	15873083	1	+	27260157	DLD1	viability	GGTGGTGGAGGGCCTGCTTATGG	SPEN	ENSG00000065526	0.415754249998966	[]	[]	4	hSpCas9	negative selection	2619195
15873084	15873107	1	-	27260157	DLD1	viability	CGTGCATGAAGTGACGGTGGGGG	SPEN	ENSG00000065526	0.701087776734703	[]	[]	8	hSpCas9	negative selection	2620522
15872939	15872962	1	+	27260157	DLD1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	1.1023153774873	[]	[]	9	hSpCas9	negative selection	2642600
15848063	15848086	1	+	27260157	DLD1	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.553455206452518	[]	[]	8	hSpCas9	negative selection	2645650
15848072	15848095	1	+	27260157	DLD1	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	-0.602133606442982	[]	[]	-5	hSpCas9	negative selection	2648856
15873090	15873113	1	+	27260157	HT1080	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.65185495771787	[]	[]	-8	hSpCas9	negative selection	2649710
15876336	15876359	1	+	27260157	HT1080	viability	ATGGGCTCTATTACGCTTCTCGG	SPEN	ENSG00000065526	-0.311059912611281	[]	[]	-7	hSpCas9	negative selection	2650985
15873019	15873042	1	-	27260157	HT1080	viability	CTCTCTACTACGAGATGCTATGG	SPEN	ENSG00000065526	0.358059275622473	[]	[]	3	hSpCas9	negative selection	2652890
15876277	15876300	1	+	27260157	HT1080	viability	TCGGACAAGACATTACGATCAGG	SPEN	ENSG00000065526	-1.31220546463392	[]	[]	-9	hSpCas9	negative selection	2653877
15848077	15848100	1	+	27260157	HT1080	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-1.29096355132669	[]	[]	-9	hSpCas9	negative selection	2654989
15872951	15872974	1	-	27260157	HT1080	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.38412511042555	[]	[]	-9	hSpCas9	negative selection	2657166
15848099	15848122	1	+	27260157	HT1080	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	0.00291516932382498	[]	[]	0	hSpCas9	negative selection	2657998
15848054	15848077	1	+	27260157	HT1080	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	-0.362431742977831	[]	[]	-7	hSpCas9	negative selection	2662635
15872955	15872978	1	+	27260157	HT1080	viability	CGCACGGATTATAATGAACCAGG	SPEN	ENSG00000065526	-0.176782729954896	[]	[]	0	hSpCas9	negative selection	2663144
15873103	15873126	1	+	27260157	HT1080	viability	CACGAGAAGGACGTTATGAGCGG	SPEN	ENSG00000065526	-0.690719127474203	[]	[]	-8	hSpCas9	negative selection	2681083
15848107	15848130	1	-	27260157	HT1080	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	-0.836951480478655	[]	[]	-8	hSpCas9	negative selection	2681624
15848129	15848152	1	+	27260157	HT1080	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	0.823530709474478	[]	[]	7	hSpCas9	negative selection	2683638
15872812	15872835	1	-	27260157	HT1080	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	1.11225087246539	[]	[]	8	hSpCas9	negative selection	2690705
15873060	15873083	1	+	27260157	HT1080	viability	GGTGGTGGAGGGCCTGCTTATGG	SPEN	ENSG00000065526	0.184599109162371	[]	[]	1	hSpCas9	negative selection	2695325
15873084	15873107	1	-	27260157	HT1080	viability	CGTGCATGAAGTGACGGTGGGGG	SPEN	ENSG00000065526	-0.741470809151994	[]	[]	-8	hSpCas9	negative selection	2696652
15872939	15872962	1	+	27260157	HT1080	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.276060380084877	[]	[]	2	hSpCas9	negative selection	2718730
15848063	15848086	1	+	27260157	HT1080	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.641625907785178	[]	[]	5	hSpCas9	negative selection	2721780
15848072	15848095	1	+	27260157	HT1080	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	0.439338452726884	[]	[]	4	hSpCas9	negative selection	2724986
15873090	15873113	1	+	27260157	MKN45	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-1.63567997110003	[]	[]	-9	hSpCas9	negative selection	2725840
15876336	15876359	1	+	27260157	MKN45	viability	ATGGGCTCTATTACGCTTCTCGG	SPEN	ENSG00000065526	-0.515351738267828	[]	[]	-6	hSpCas9	negative selection	2727115
15873019	15873042	1	-	27260157	MKN45	viability	CTCTCTACTACGAGATGCTATGG	SPEN	ENSG00000065526	0.172564335722787	[]	[]	5	hSpCas9	negative selection	2729020
15876277	15876300	1	+	27260157	MKN45	viability	TCGGACAAGACATTACGATCAGG	SPEN	ENSG00000065526	-0.0754002845360126	[]	[]	0	hSpCas9	negative selection	2730007
15848077	15848100	1	+	27260157	MKN45	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-1.64357335922068	[]	[]	-9	hSpCas9	negative selection	2731119
15872951	15872974	1	-	27260157	MKN45	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.41265063802514	[]	[]	-8	hSpCas9	negative selection	2733296
15848099	15848122	1	+	27260157	MKN45	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	-0.245531197925118	[]	[]	-1	hSpCas9	negative selection	2734128
15848054	15848077	1	+	27260157	MKN45	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	-0.597822651267573	[]	[]	-6	hSpCas9	negative selection	2738765
15872955	15872978	1	+	27260157	MKN45	viability	CGCACGGATTATAATGAACCAGG	SPEN	ENSG00000065526	-1.46066958111926	[]	[]	-8	hSpCas9	negative selection	2739274
15873103	15873126	1	+	27260157	MKN45	viability	CACGAGAAGGACGTTATGAGCGG	SPEN	ENSG00000065526	0.132911933208579	[]	[]	4	hSpCas9	negative selection	2757213
15848107	15848130	1	-	27260157	MKN45	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	0.251256237900262	[]	[]	5	hSpCas9	negative selection	2757754
15848129	15848152	1	+	27260157	MKN45	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	0.604399530257995	[]	[]	7	hSpCas9	negative selection	2759768
15872812	15872835	1	-	27260157	MKN45	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	0.229803979997433	[]	[]	5	hSpCas9	negative selection	2766835
15873060	15873083	1	+	27260157	MKN45	viability	GGTGGTGGAGGGCCTGCTTATGG	SPEN	ENSG00000065526	-0.272115935463601	[]	[]	-1	hSpCas9	negative selection	2771455
15873084	15873107	1	-	27260157	MKN45	viability	CGTGCATGAAGTGACGGTGGGGG	SPEN	ENSG00000065526	-0.954183580319205	[]	[]	-7	hSpCas9	negative selection	2772782
15872939	15872962	1	+	27260157	MKN45	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	1.35242679855384	[]	[]	9	hSpCas9	negative selection	2794860
15848063	15848086	1	+	27260157	MKN45	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.967852794146134	[]	[]	-7	hSpCas9	negative selection	2797910
15848072	15848095	1	+	27260157	MKN45	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	-0.425684245188837	[]	[]	-6	hSpCas9	negative selection	2801116
15873090	15873113	1	+	27260157	RKO	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.305588664422953	[]	[]	1	hSpCas9	negative selection	2801970
15876336	15876359	1	+	27260157	RKO	viability	ATGGGCTCTATTACGCTTCTCGG	SPEN	ENSG00000065526	-0.0940363646032817	[]	[]	0	hSpCas9	negative selection	2803245
15873019	15873042	1	-	27260157	RKO	viability	CTCTCTACTACGAGATGCTATGG	SPEN	ENSG00000065526	0.689390823820107	[]	[]	7	hSpCas9	negative selection	2805150
15876277	15876300	1	+	27260157	RKO	viability	TCGGACAAGACATTACGATCAGG	SPEN	ENSG00000065526	-0.00544912270444887	[]	[]	0	hSpCas9	negative selection	2806137
15848077	15848100	1	+	27260157	RKO	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-0.547471598569777	[]	[]	-7	hSpCas9	negative selection	2807249
15872951	15872974	1	-	27260157	RKO	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.279901988877856	[]	[]	-1	hSpCas9	negative selection	2809426
15848099	15848122	1	+	27260157	RKO	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	1.07625036446611	[]	[]	9	hSpCas9	negative selection	2810258
15848054	15848077	1	+	27260157	RKO	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	0.975849966536671	[]	[]	9	hSpCas9	negative selection	2814895
15872955	15872978	1	+	27260157	RKO	viability	CGCACGGATTATAATGAACCAGG	SPEN	ENSG00000065526	-0.886486295944431	[]	[]	-8	hSpCas9	negative selection	2815404
15873103	15873126	1	+	27260157	RKO	viability	CACGAGAAGGACGTTATGAGCGG	SPEN	ENSG00000065526	0.901331249651289	[]	[]	8	hSpCas9	negative selection	2833343
15848107	15848130	1	-	27260157	RKO	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	0.163962176095044	[]	[]	0	hSpCas9	negative selection	2833884
15848129	15848152	1	+	27260157	RKO	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	1.55007368154587	[]	[]	9	hSpCas9	negative selection	2835898
15872812	15872835	1	-	27260157	RKO	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	0.488265287908833	[]	[]	2	hSpCas9	negative selection	2842965
15873060	15873083	1	+	27260157	RKO	viability	GGTGGTGGAGGGCCTGCTTATGG	SPEN	ENSG00000065526	-0.00835295158550834	[]	[]	0	hSpCas9	negative selection	2847585
15873084	15873107	1	-	27260157	RKO	viability	CGTGCATGAAGTGACGGTGGGGG	SPEN	ENSG00000065526	-0.970927817132402	[]	[]	-8	hSpCas9	negative selection	2848912
15872939	15872962	1	+	27260157	RKO	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	1.517917914766	[]	[]	9	hSpCas9	negative selection	2870990
15848063	15848086	1	+	27260157	RKO	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	0.819868022349593	[]	[]	8	hSpCas9	negative selection	2874040
15848072	15848095	1	+	27260157	RKO	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	0.0110477920939685	[]	[]	0	hSpCas9	negative selection	2877246
15873090	15873113	1	+	27260157	SF268	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-1.05734602771057	[]	[]	-7	hSpCas9	negative selection	2878100
15876336	15876359	1	+	27260157	SF268	viability	ATGGGCTCTATTACGCTTCTCGG	SPEN	ENSG00000065526	-0.096042815141785	[]	[]	0	hSpCas9	negative selection	2879375
15873019	15873042	1	-	27260157	SF268	viability	CTCTCTACTACGAGATGCTATGG	SPEN	ENSG00000065526	-0.50341198282905	[]	[]	-4	hSpCas9	negative selection	2881280
15876277	15876300	1	+	27260157	SF268	viability	TCGGACAAGACATTACGATCAGG	SPEN	ENSG00000065526	-0.41536214553046	[]	[]	-3	hSpCas9	negative selection	2882267
15848077	15848100	1	+	27260157	SF268	viability	GAAACCAGGCATCTCTGGGTGGG	SPEN	ENSG00000065526	-1.27839327897542	[]	[]	-7	hSpCas9	negative selection	2883379
15872951	15872974	1	-	27260157	SF268	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.900809280336241	[]	[]	-6	hSpCas9	negative selection	2885556
15848099	15848122	1	+	27260157	SF268	viability	GCAACTTACCCGAGAACGTGCGG	SPEN	ENSG00000065526	0.342709345807534	[]	[]	4	hSpCas9	negative selection	2886388
15848054	15848077	1	+	27260157	SF268	viability	GCACGCCGCCCAGCATGGTCCGG	SPEN	ENSG00000065526	0.176631353530722	[]	[]	0	hSpCas9	negative selection	2891025
15872955	15872978	1	+	27260157	SF268	viability	CGCACGGATTATAATGAACCAGG	SPEN	ENSG00000065526	-0.820450147545912	[]	[]	-6	hSpCas9	negative selection	2891534
15873103	15873126	1	+	27260157	SF268	viability	CACGAGAAGGACGTTATGAGCGG	SPEN	ENSG00000065526	0.32663899572961	[]	[]	4	hSpCas9	negative selection	2909473
15848107	15848130	1	-	27260157	SF268	viability	TTCTCTTCCCGCACGTTCTCGGG	SPEN	ENSG00000065526	0.792442690124173	[]	[]	8	hSpCas9	negative selection	2910014
15848129	15848152	1	+	27260157	SF268	viability	AGATCATCGAGCATTTCAAACGG	SPEN	ENSG00000065526	0.00991910691833387	[]	[]	0	hSpCas9	negative selection	2912028
15872812	15872835	1	-	27260157	SF268	viability	ACTTTCCACGCGGCCATATCTGG	SPEN	ENSG00000065526	0.683313252892681	[]	[]	8	hSpCas9	negative selection	2919095
15873060	15873083	1	+	27260157	SF268	viability	GGTGGTGGAGGGCCTGCTTATGG	SPEN	ENSG00000065526	0.0664981727648315	[]	[]	0	hSpCas9	negative selection	2923715
15873084	15873107	1	-	27260157	SF268	viability	CGTGCATGAAGTGACGGTGGGGG	SPEN	ENSG00000065526	-0.885500187035175	[]	[]	-6	hSpCas9	negative selection	2925042
15872939	15872962	1	+	27260157	SF268	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	1.00709374811196	[]	[]	9	hSpCas9	negative selection	2947120
15848063	15848086	1	+	27260157	SF268	viability	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.470968552017629	[]	[]	-4	hSpCas9	negative selection	2950170
15848072	15848095	1	+	27260157	SF268	viability	TCCGGGAAACCAGGCATCTCTGG	SPEN	ENSG00000065526	-0.294476230642343	[]	[]	-2	hSpCas9	negative selection	2953376
15928850	15928873	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	0.3044488494238279	[3,3]	[2,4]	6	hSpCas9	positive selection	3023304
15930870	15930893	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.15731502285672422	[5,5]	[5,2]	-2	hSpCas9	positive selection	3023305
15928836	15928859	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	-0.24194515882024892	[3,3]	[4,0]	-3	hSpCas9	positive selection	3023306
15876440	15876463	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	-0.4897906136241837	[3,3]	[3,0]	-6	hSpCas9	positive selection	3023307
15928850	15928873	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	-0.6880886602591884	[3,3]	[2,0]	-8	hSpCas9	positive selection	3091162
15930870	15930893	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	0.011535046626528711	[5,5]	[4,2]	0	hSpCas9	positive selection	3091163
15928836	15928859	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	-0.1089389068721371	[3,3]	[2,1]	-1	hSpCas9	positive selection	3091164
15876440	15876463	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	-0.15282572470238553	[3,3]	[3,0]	-2	hSpCas9	positive selection	3091165
15911229	15911252		+	24336571	A375	resistance to PLX after 7 days	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.18053519985700506	[4,4]	[3,4]	-6	hSpCas9	positive selection	3147077
15873090	15873113		+	24336571	A375	resistance to PLX after 7 days	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.11744775655068351	[5,4]	[5,5]	4	hSpCas9	positive selection	3147078
15873114	15873137		+	24336571	A375	resistance to PLX after 7 days	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	-0.13983078836384966	[8,5]	[6,5]	-4	hSpCas9	positive selection	3147079
15911151	15911174		+	24336571	A375	resistance to PLX after 7 days	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.2500804733128825	[6,5]	[4,4]	-7	hSpCas9	positive selection	3147080
15872951	15872974		-	24336571	A375	resistance to PLX after 7 days	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.09239415925485694	[6,5]	[5,5]	-3	hSpCas9	positive selection	3147081
15911097	15911120		+	24336571	A375	resistance to PLX after 7 days	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	0.06277907272308458	[5,5]	[6,5]	2	hSpCas9	positive selection	3147082
15911229	15911252		+	24336571	A375	resistance to PLX after 14 days	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.20042415117463097	[4,4]	[1,2]	2	hSpCas9	positive selection	3204870
15873090	15873113		+	24336571	A375	resistance to PLX after 14 days	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.12065417206015483	[3,7]	[1,2]	1	hSpCas9	positive selection	3204871
15873114	15873137		+	24336571	A375	resistance to PLX after 14 days	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	0.3203025785615	[5,6]	[2,3]	3	hSpCas9	positive selection	3204872
15911151	15911174		+	24336571	A375	resistance to PLX after 14 days	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.03333948454859037	[3,4]	[1,1]	0	hSpCas9	positive selection	3204873
15872951	15872974		-	24336571	A375	resistance to PLX after 14 days	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.020765020782213428	[4,5]	[1,1]	0	hSpCas9	positive selection	3204874
15911097	15911120		+	24336571	A375	resistance to PLX after 14 days	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	1.0510240893087959	[3,4]	[2,4]	8	hSpCas9	positive selection	3204875
15911229	15911252		+	24336571	A375	viability after 7 days	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.2714278140727542	[6]	[4,4]	-4	hSpCas9	negative selection	3262663
15873090	15873113		+	24336571	A375	viability after 7 days	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.6887762365367003	[9]	[5,4]	-7	hSpCas9	negative selection	3262664
15873114	15873137		+	24336571	A375	viability after 7 days	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	-0.004607863229011522	[7]	[8,5]	0	hSpCas9	negative selection	3262665
15911151	15911174		+	24336571	A375	viability after 7 days	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.18130855685448266	[7]	[6,5]	-3	hSpCas9	negative selection	3262666
15872951	15872974		-	24336571	A375	viability after 7 days	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.010884634119171	[13]	[6,5]	-9	hSpCas9	negative selection	3262667
15911097	15911120		+	24336571	A375	viability after 7 days	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	-1.1426985138288697	[14]	[5,5]	-9	hSpCas9	negative selection	3262668
15911229	15911252		+	24336571	A375	viability after 14 days	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.28685926378084026	[6]	[4,4]	-3	hSpCas9	negative selection	3320456
15873090	15873113		+	24336571	A375	viability after 14 days	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.6018391414291788	[9]	[3,7]	-6	hSpCas9	negative selection	3320457
15873114	15873137		+	24336571	A375	viability after 14 days	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	-0.14513839565480036	[7]	[5,6]	-2	hSpCas9	negative selection	3320458
15911151	15911174		+	24336571	A375	viability after 14 days	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.520434320107264	[7]	[3,4]	-6	hSpCas9	negative selection	3320459
15872951	15872974		-	24336571	A375	viability after 14 days	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.2538643820590385	[13]	[4,5]	-9	hSpCas9	negative selection	3320460
15911097	15911120		+	24336571	A375	viability after 14 days	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	-1.6608074559029087	[14]	[3,4]	-9	hSpCas9	negative selection	3320461
15919030	15919053	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-1.1392785697360233	[336,336]	[0,0]	-7	hSpCas9	positive selection	3394647
15911229	15911252	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.9174762085612103	[80,80]	[0,0]	4	hSpCas9	positive selection	3394648
15911151	15911174	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.7654731151161606	[89,89]	[0,0]	4	hSpCas9	positive selection	3394649
15928850	15928873	1	-	26780180	HT29	viability (Avana library 4 designs)	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	-0.8371755677166	[]	[]	-9	hSpCas9	negative selection	3461926
15930869	15930892	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.661504204330071	[]	[]	-8	hSpCas9	negative selection	3461927
15928835	15928858	1	+	26780180	HT29	viability (Avana library 4 designs)	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	0.545331205902498	[]	[]	2	hSpCas9	negative selection	3461928
15876439	15876462	1	+	26780180	HT29	viability (Avana library 4 designs)	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	0.564866107024752	[]	[]	2	hSpCas9	negative selection	3461929
15928850	15928873	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	1.82055150171215	[]	[]	2	hSpCas9	negative selection	3563212
15928835	15928858	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	-2.03693154390686	[]	[]	-2	hSpCas9	negative selection	3563213
15876439	15876462	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	-7.53853283767231	[]	[]	-7	hSpCas9	negative selection	3563214
15930869	15930892	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-4.38877647416371	[]	[]	-5	hSpCas9	negative selection	3563215
15930994	15931017	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGATTTATGGAGCTCACACGG	SPEN	ENSG00000065526	-0.610434690730535	[]	[]	0	hSpCas9	negative selection	3563216
15931194	15931217	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCACTAGAGAAGACCACTGG	SPEN	ENSG00000065526	-12.2998505538135	[]	[]	-8	hSpCas9	negative selection	3563217
15928850	15928873	1	-	26780180	A375	viability (Avana lentiGuide)	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	-1.28828198093706	[]	[]	-2	hSpCas9	negative selection	3671871
15928835	15928858	1	+	26780180	A375	viability (Avana lentiGuide)	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	3.99622127346808	[]	[]	4	hSpCas9	negative selection	3671872
15876439	15876462	1	+	26780180	A375	viability (Avana lentiGuide)	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	-3.35602411965956	[]	[]	-6	hSpCas9	negative selection	3671873
15930869	15930892	1	+	26780180	A375	viability (Avana lentiGuide)	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	7.24982261983443	[]	[]	6	hSpCas9	negative selection	3671874
15930994	15931017	1	+	26780180	A375	viability (Avana lentiGuide)	GCAGATTTATGGAGCTCACACGG	SPEN	ENSG00000065526	3.88867578071515	[]	[]	4	hSpCas9	negative selection	3671875
15931194	15931217	1	+	26780180	A375	viability (Avana lentiGuide)	TCAGCACTAGAGAAGACCACTGG	SPEN	ENSG00000065526	27.5594947577207	[]	[]	9	hSpCas9	negative selection	3671876
15928850	15928873	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	-0.09362326804945502	[4]	[4,3]	-1	hSpCas9	positive selection	3780478
15928835	15928858	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	-0.18717222869935404	[4]	[3,3]	-3	hSpCas9	positive selection	3780479
15876439	15876462	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	-0.6080120219512133	[4]	[2,2]	-7	hSpCas9	positive selection	3780480
15930869	15930892	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.2413421284819655	[6]	[4,4]	-4	hSpCas9	positive selection	3780481
15930994	15931017	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGATTTATGGAGCTCACACGG	SPEN	ENSG00000065526	-0.135998928036701	[5]	[4,5]	-2	hSpCas9	positive selection	3780482
15931194	15931217	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCACTAGAGAAGACCACTGG	SPEN	ENSG00000065526	-1.1373919490468687	[4]	[1,1]	-9	hSpCas9	positive selection	3780483
15928850	15928873	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCAAGGCATGAGTTCCAGGCGG	SPEN	ENSG00000065526	0.4589854606875531	[5]	[5,6]	9	hSpCas9	positive selection	3889085
15928835	15928858	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAATAGCGAAAAACCGCCTGG	SPEN	ENSG00000065526	-0.2576562571171878	[5]	[3,4]	-3	hSpCas9	positive selection	3889086
15876439	15876462	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTACACAGGGATATCTACAGGG	SPEN	ENSG00000065526	0.2641747143197651	[4]	[4,4]	7	hSpCas9	positive selection	3889087
15930869	15930892	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.013810533313579287	[7]	[5,6]	0	hSpCas9	positive selection	3889088
15930994	15931017	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGATTTATGGAGCTCACACGG	SPEN	ENSG00000065526	-0.06235821629688704	[7]	[4,6]	-1	hSpCas9	positive selection	3889089
15931194	15931217	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCACTAGAGAAGACCACTGG	SPEN	ENSG00000065526	-0.1707554648597376	[5]	[2,5]	-2	hSpCas9	positive selection	3889090
15911229	15911252	1	+	26780180	A375	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	1.54471726551939	[]	[]	8	hSpCas9	negative selection	3998837
15873090	15873113	1	+	26780180	A375	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.90627200886549	[]	[]	4	hSpCas9	negative selection	3998838
15911151	15911174	1	+	26780180	A375	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	1.22242998964484	[]	[]	6	hSpCas9	negative selection	3998839
15872951	15872974	1	-	26780180	A375	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	1.80877575121912	[]	[]	9	hSpCas9	negative selection	3998840
15918956	15918979	1	-	26780180	A375	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	1.9379263912771	[]	[]	9	hSpCas9	negative selection	3998841
15919030	15919053	1	+	26780180	A375	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	1.14436419643025	[]	[]	6	hSpCas9	negative selection	3998842
15911229	15911252	1	+	26780180	HT29	viability (GeCKOv2 library)	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.735075744924888	[]	[]	3	hSpCas9	negative selection	4106803
15873090	15873113	1	+	26780180	HT29	viability (GeCKOv2 library)	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.0700336334110009	[]	[]	-2	hSpCas9	negative selection	4106804
15911151	15911174	1	+	26780180	HT29	viability (GeCKOv2 library)	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.870834586892612	[]	[]	3	hSpCas9	negative selection	4106805
15872951	15872974	1	-	26780180	HT29	viability (GeCKOv2 library)	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.985281700673195	[]	[]	4	hSpCas9	negative selection	4106806
15918956	15918979	1	-	26780180	HT29	viability (GeCKOv2 library)	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.0355765307102115	[]	[]	-1	hSpCas9	negative selection	4106807
15919030	15919053	1	+	26780180	HT29	viability (GeCKOv2 library)	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.184683062063208	[]	[]	0	hSpCas9	negative selection	4106808
15911229	15911252	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.12364806834708952	[1]	[0,0]	3	hSpCas9	positive selection	4173230
15873090	15873113	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.2985491959887202	[2]	[0,1]	-6	hSpCas9	positive selection	4173231
15873114	15873137	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	0.275010463686278	[2]	[1,1]	7	hSpCas9	positive selection	4173232
15911151	15911174	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.21921136321096762	[2]	[1,0]	-5	hSpCas9	positive selection	4173233
15872951	15872974	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.24802946519359131	[3]	[2,0]	-5	hSpCas9	positive selection	4173234
15911097	15911120	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	0.6023832880383694	[3]	[4,1]	9	hSpCas9	positive selection	4173235
15911229	15911252	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.3530584606552025	[2]	[3,0,0,0]	2	hSpCas9	positive selection	4237252
15873090	15873113	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.31428556621158976	[3]	[4,2,1,0]	2	hSpCas9	positive selection	4237253
15873114	15873137	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTTATGAGCGGAGACTTGATGG	SPEN	ENSG00000065526	0.5063240983274514	[2]	[0,3,3,0]	3	hSpCas9	positive selection	4237254
15911151	15911174	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.6803370061744052	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4237255
15872951	15872974	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.7636995150541652	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4237256
15911097	15911120	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTAGATACAAGCCTTAAAGATGG	SPEN	ENSG00000065526	-0.9442993493801396	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4237257
15872951	15872974	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.19008787967670282	[3]	[2,1]	-4	hSpCas9	positive selection	4300245
15873090	15873113	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.1264749184759283	[3]	[3,2]	2	hSpCas9	positive selection	4300246
15918956	15918979	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.10241517370867947	[4]	[3,2]	-2	hSpCas9	positive selection	4300247
15919030	15919053	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.2672602446089449	[4]	[4,3]	5	hSpCas9	positive selection	4364501
15911229	15911252	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.2958553587991599	[3]	[2,1]	-6	hSpCas9	positive selection	4364502
15911151	15911174	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.18290524573615868	[3]	[2,1]	-4	hSpCas9	positive selection	4364503
15873091	15873113	1	+	27760321	OCIAML3	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.443116366121052	[478,471]	[387,661]	5	hSpCas9	negative selection	4442663
15928180	15928202	1	+	27760321	OCIAML3	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	-0.005873611135439605	[680,532]	[420,532]	0	hSpCas9	negative selection	4442664
15929854	15929876	1	+	27760321	OCIAML3	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-0.00867552501765903	[505,435]	[332,406]	0	hSpCas9	negative selection	4442665
15876391	15876413	1	-	27760321	OCIAML3	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.24605602149291358	[410,325]	[218,496]	3	hSpCas9	negative selection	4442666
15876465	15876487	1	+	27760321	OCIAML3	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	1.0909618614476133	[423,354]	[565,750]	9	hSpCas9	negative selection	4442667
15873091	15873113	1	+	27760321	OCIAML2	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.21446645417443455	[478,471]	[271,411]	-3	hSpCas9	negative selection	4526126
15928180	15928202	1	+	27760321	OCIAML2	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.583680029925616	[680,532]	[632,859]	7	hSpCas9	negative selection	4526127
15929854	15929876	1	+	27760321	OCIAML2	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.30207227319818153	[505,435]	[382,580]	4	hSpCas9	negative selection	4526128
15876391	15876413	1	-	27760321	OCIAML2	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.34713104960709595	[410,325]	[252,539]	5	hSpCas9	negative selection	4526129
15876465	15876487	1	+	27760321	OCIAML2	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.16254894408547818	[423,354]	[222,355]	-2	hSpCas9	negative selection	4526130
15873091	15873113	1	+	27760321	MV411	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.32314017330716394	[478,471]	[405,374]	2	hSpCas9	negative selection	4609589
15928180	15928202	1	+	27760321	MV411	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.6978331454979152	[680,532]	[604,705]	5	hSpCas9	negative selection	4609590
15929854	15929876	1	+	27760321	MV411	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.4992290919428691	[505,435]	[539,284]	3	hSpCas9	negative selection	4609591
15876391	15876413	1	-	27760321	MV411	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.7192135678259942	[410,325]	[466,293]	5	hSpCas9	negative selection	4609592
15876465	15876487	1	+	27760321	MV411	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	2.3339872701757556	[423,354]	[1986,244]	9	hSpCas9	negative selection	4609593
15873091	15873113	1	+	27760321	HL60	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.0841725576534678	[478,471]	[396,335]	-1	hSpCas9	negative selection	4693052
15928180	15928202	1	+	27760321	HL60	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.4050032319552098	[680,532]	[672,629]	5	hSpCas9	negative selection	4693053
15929854	15929876	1	+	27760321	HL60	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-0.11354561080888738	[505,435]	[391,314]	-1	hSpCas9	negative selection	4693054
15876391	15876413	1	-	27760321	HL60	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.0341615648634884	[410,325]	[283,329]	0	hSpCas9	negative selection	4693055
15876465	15876487	1	+	27760321	HL60	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.8328867239418998	[423,354]	[174,180]	-7	hSpCas9	negative selection	4693056
15873091	15873113	1	+	27760321	HT1080	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.33607765904029085	[471,368]	[189,69]	-1	hSpCas9	negative selection	4776515
15928180	15928202	1	+	27760321	HT1080	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	-1.9932824344436657	[532,415]	[46,47]	-6	hSpCas9	negative selection	4776516
15929854	15929876	1	+	27760321	HT1080	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-0.6491791066367778	[435,339]	[46,154]	-3	hSpCas9	negative selection	4776517
15876391	15876413	1	-	27760321	HT1080	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	-0.6875771758838143	[325,254]	[68,74]	-3	hSpCas9	negative selection	4776518
15876465	15876487	1	+	27760321	HT1080	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-2.86909500673619	[354,276]	[0,34]	-7	hSpCas9	negative selection	4776519
15873091	15873113	1	+	27760321	HT29	viability after 7 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.10970381454227968	[471,368]	[640,608,509]	1	hSpCas9	negative selection	4859978
15928180	15928202	1	+	27760321	HT29	viability after 7 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.3059997984102808	[532,415]	[738,1039,488]	5	hSpCas9	negative selection	4859979
15929854	15929876	1	+	27760321	HT29	viability after 7 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-0.18916251003768297	[435,339]	[600,319,414]	-3	hSpCas9	negative selection	4859980
15876391	15876413	1	-	27760321	HT29	viability after 7 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.46092864043633924	[325,254]	[632,452,473]	7	hSpCas9	negative selection	4859981
15876465	15876487	1	+	27760321	HT29	viability after 7 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.23343480461639743	[354,276]	[341,419,275]	-3	hSpCas9	negative selection	4859982
15873091	15873113	1	+	27760321	HT29	viability after 25 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.2432601435727862	[471,368]	[318,501,938]	2	hSpCas9	negative selection	4943441
15928180	15928202	1	+	27760321	HT29	viability after 25 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.2839925532320473	[532,415]	[560,712,717]	3	hSpCas9	negative selection	4943442
15929854	15929876	1	+	27760321	HT29	viability after 25 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.18158443888012432	[435,339]	[409,554,553]	1	hSpCas9	negative selection	4943443
15876391	15876413	1	-	27760321	HT29	viability after 25 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.5378277238108897	[325,254]	[525,396,523]	6	hSpCas9	negative selection	4943444
15876465	15876487	1	+	27760321	HT29	viability after 25 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.0981999605534819	[354,276]	[195,430,399]	-1	hSpCas9	negative selection	4943445
15873091	15873113	1	+	27760321	HT29	viability after 22 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.15321570759080555	[471,368]	[372,426,513]	-1	hSpCas9	negative selection	5026904
15928180	15928202	1	+	27760321	HT29	viability after 22 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.4998220975691028	[532,415]	[893,838,588]	5	hSpCas9	negative selection	5026905
15929854	15929876	1	+	27760321	HT29	viability after 22 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.45019195637218995	[435,339]	[686,569,578]	5	hSpCas9	negative selection	5026906
15876391	15876413	1	-	27760321	HT29	viability after 22 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.41295797883874613	[325,254]	[556,500,278]	4	hSpCas9	negative selection	5026907
15876465	15876487	1	+	27760321	HT29	viability after 22 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.4477483348445007	[354,276]	[202,360,240]	-4	hSpCas9	negative selection	5026908
15873091	15873113	1	+	27760321	HT29	viability after 19 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.2163392083480898	[471,368]	[465,309,468]	-2	hSpCas9	negative selection	5110367
15928180	15928202	1	+	27760321	HT29	viability after 19 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.26108725221618045	[532,415]	[920,758,311]	2	hSpCas9	negative selection	5110368
15929854	15929876	1	+	27760321	HT29	viability after 19 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.4670756815806019	[435,339]	[511,594,717]	4	hSpCas9	negative selection	5110369
15876391	15876413	1	-	27760321	HT29	viability after 19 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.7704235270531259	[325,254]	[561,556,579]	7	hSpCas9	negative selection	5110370
15876465	15876487	1	+	27760321	HT29	viability after 19 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.7451867266454676	[354,276]	[263,339,53]	-5	hSpCas9	negative selection	5110371
15873091	15873113	1	+	27760321	HT29	viability after 16 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.15651115965451778	[471,368]	[756,376,464]	1	hSpCas9	negative selection	5193830
15928180	15928202	1	+	27760321	HT29	viability after 16 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.1904241204503666	[532,415]	[674,673,472]	2	hSpCas9	negative selection	5193831
15929854	15929876	1	+	27760321	HT29	viability after 16 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-0.1606607259059281	[435,339]	[229,501,414]	-2	hSpCas9	negative selection	5193832
15876391	15876413	1	-	27760321	HT29	viability after 16 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.6380351178799124	[325,254]	[500,621,390]	7	hSpCas9	negative selection	5193833
15876465	15876487	1	+	27760321	HT29	viability after 16 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.29919914662436087	[354,276]	[233,320,300]	-3	hSpCas9	negative selection	5193834
15873091	15873113	1	+	27760321	HT29	viability after 13 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.06688984102153883	[471,368]	[502,569,462]	0	hSpCas9	negative selection	5277293
15928180	15928202	1	+	27760321	HT29	viability after 13 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.4435223336507744	[532,415]	[876,681,689]	5	hSpCas9	negative selection	5277294
15929854	15929876	1	+	27760321	HT29	viability after 13 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.2005334633364938	[435,339]	[509,684,365]	2	hSpCas9	negative selection	5277295
15876391	15876413	1	-	27760321	HT29	viability after 13 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.30996618991006525	[325,254]	[437,509,311]	4	hSpCas9	negative selection	5277296
15876465	15876487	1	+	27760321	HT29	viability after 13 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	0.10535588142894488	[354,276]	[371,551,266]	1	hSpCas9	negative selection	5277297
15873091	15873113	1	+	27760321	HT29	viability after 10 days	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.1708488200602712	[471,368]	[425,419,549]	-2	hSpCas9	negative selection	5360756
15928180	15928202	1	+	27760321	HT29	viability after 10 days	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.556608930325406	[532,415]	[715,1041,860]	7	hSpCas9	negative selection	5360757
15929854	15929876	1	+	27760321	HT29	viability after 10 days	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	0.5531508437329355	[435,339]	[644,715,769]	7	hSpCas9	negative selection	5360758
15876391	15876413	1	-	27760321	HT29	viability after 10 days	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	0.3282324869852125	[325,254]	[310,635,424]	4	hSpCas9	negative selection	5360759
15876465	15876487	1	+	27760321	HT29	viability after 10 days	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.5944668863093073	[354,276]	[145,375,264]	-6	hSpCas9	negative selection	5360760
15873091	15873113	1	+	27760321	MOLM13	viability	CGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.22794643946923657	[478,471]	[327,303]	1	hSpCas9	negative selection	5444219
15928180	15928202	1	+	27760321	MOLM13	viability	GGCGGGACTATCCAGCTCGAGG	SPEN	ENSG00000065526	0.17218933274345505	[680,532]	[365,397]	1	hSpCas9	negative selection	5444220
15929854	15929876	1	+	27760321	MOLM13	viability	GTAGCCTCGTTCACGAGGTAGG	SPEN	ENSG00000065526	-1.013374357911665	[505,435]	[93,162]	-6	hSpCas9	negative selection	5444221
15876391	15876413	1	-	27760321	MOLM13	viability	AGCCCTAGGTTCATATCGGGGG	SPEN	ENSG00000065526	-0.5716876952390071	[410,325]	[205,81]	-4	hSpCas9	negative selection	5444222
15876465	15876487	1	+	27760321	MOLM13	viability	ATATTACCCGGGAGGTACGAGG	SPEN	ENSG00000065526	-0.19367308296050392	[423,354]	[118,252]	-1	hSpCas9	negative selection	5444223
15847899	15847922	1	+	27661255	K562	viability	GAGGGATGGTCTCTGCACGGGGG	SPEN	ENSG00000065526	0.08056596458721654	[1142,1217]	[1083,920]	3	dCas9-KRAB	negative selection	5513900
15848249	15848272	1	+	27661255	K562	viability	GGACTCCGGCCCGGACCCACGGG	SPEN	ENSG00000065526	-0.025816010026480818	[894,1222]	[808,840]	-1	dCas9-KRAB	negative selection	5513901
15872951	15872974	1	-	27260156	BXPC3	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.2694807685073479	[759]	[866,1016,910,1045]	6	hSpCas9	negative selection	5572705
15873090	15873113	1	+	27260156	BXPC3	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.23685720648009023	[556]	[660,610,703,783]	5	hSpCas9	negative selection	5572706
15918956	15918979	1	-	27260156	BXPC3	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.20322307809594142	[1628]	[1842,1798,1927,2326]	4	hSpCas9	negative selection	5572707
15919030	15919053	1	+	27260156	BXPC3	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.18446671964262285	[1059]	[1249,1192,1185,1423]	4	hSpCas9	negative selection	5636961
15911229	15911252	1	+	27260156	BXPC3	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.07437746225131803	[898]	[816,1004,1093,1064]	1	hSpCas9	negative selection	5636962
15911151	15911174	1	+	27260156	BXPC3	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.2836037837677448	[623]	[549,944,659,1064]	6	hSpCas9	negative selection	5636963
15872951	15872974	1	-	27260156	A673	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.37662894382942097	[759]	[746,640,763,661]	-7	hSpCas9	negative selection	5693956
15873090	15873113	1	+	27260156	A673	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.10896390640602877	[556]	[757,698,674,758]	2	hSpCas9	negative selection	5693957
15918956	15918979	1	-	27260156	A673	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.39163973816063624	[1628]	[1720,1572,1201,1491]	-7	hSpCas9	negative selection	5693958
15919030	15919053	1	+	27260156	A673	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.02775866339688693	[1059]	[1464,1242,1125,1179]	0	hSpCas9	negative selection	5758212
15911229	15911252	1	+	27260156	A673	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.17621350369330357	[898]	[1023,993,755,1059]	-4	hSpCas9	negative selection	5758213
15911151	15911174	1	+	27260156	A673	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.00793719594519926	[623]	[765,632,901,711]	0	hSpCas9	negative selection	5758214
15872951	15872974	1	-	27260156	A375	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.0332985716234169	[759]	[410,498,480,359]	-8	hSpCas9	negative selection	5815207
15873090	15873113	1	+	27260156	A375	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.4804763021520304	[556]	[289,580,512,490]	-6	hSpCas9	negative selection	5815208
15918956	15918979	1	-	27260156	A375	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-1.0251067927822324	[1628]	[1172,875,795,889]	-8	hSpCas9	negative selection	5815209
15919030	15919053	1	+	27260156	A375	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.03986207346734827	[1059]	[1669,1169,1075,1170]	0	hSpCas9	negative selection	5879463
15911229	15911252	1	+	27260156	A375	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-1.021435683315014	[898]	[506,476,648,437]	-8	hSpCas9	negative selection	5879464
15911151	15911174	1	+	27260156	A375	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.3122392543930176	[623]	[624,767,694,315]	-4	hSpCas9	negative selection	5879465
15872951	15872974	1	-	27260156	COLO741	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.3778481178568488	[759]	[724,843,674]	-7	hSpCas9	negative selection	5936458
15873090	15873113	1	+	27260156	COLO741	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.021010872835308225	[556]	[902,697,588]	0	hSpCas9	negative selection	5936459
15918956	15918979	1	-	27260156	COLO741	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.3312017941088219	[1628]	[1787,1769,1429]	-6	hSpCas9	negative selection	5936460
15919030	15919053	1	+	27260156	COLO741	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.0948087061071845	[1059]	[1697,1453,1221]	2	hSpCas9	negative selection	6000714
15911229	15911252	1	+	27260156	COLO741	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.14141433617108667	[898]	[1145,1074,918]	-3	hSpCas9	negative selection	6000715
15911151	15911174	1	+	27260156	COLO741	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.10578983725496632	[623]	[1085,830,686]	2	hSpCas9	negative selection	6000716
15872951	15872974	1	-	27260156	CAL120	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-1.1257044632682884	[759]	[451,481,369]	-9	hSpCas9	negative selection	6057709
15873090	15873113	1	+	27260156	CAL120	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.3123792890890805	[556]	[1185,770,676]	5	hSpCas9	negative selection	6057710
15918956	15918979	1	-	27260156	CAL120	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.8194584338897813	[1628]	[996,1404,1022]	-8	hSpCas9	negative selection	6057711
15919030	15919053	1	+	27260156	CAL120	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.1518242241399903	[1059]	[1960,1197,1313]	2	hSpCas9	negative selection	6121965
15911229	15911252	1	+	27260156	CAL120	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.5517383233444834	[898]	[1112,585,644]	-7	hSpCas9	negative selection	6121966
15911151	15911174	1	+	27260156	CAL120	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.6132929111976719	[623]	[453,411,645]	-7	hSpCas9	negative selection	6121967
15872951	15872974	1	-	27260156	CADOES1	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.004254362172800508	[759]	[754,652,781,642]	0	hSpCas9	negative selection	6178960
15873090	15873113	1	+	27260156	CADOES1	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.18397628726850668	[556]	[605,519,557,672]	3	hSpCas9	negative selection	6178961
15918956	15918979	1	-	27260156	CADOES1	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.12943594081045684	[1628]	[1297,1583,1499,1149]	-2	hSpCas9	negative selection	6178962
15919030	15919053	1	+	27260156	CADOES1	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.2608616622610265	[1059]	[1274,1073,1029,1351]	4	hSpCas9	negative selection	6243216
15911229	15911252	1	+	27260156	CADOES1	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.03375342834567474	[898]	[598,879,864,927]	0	hSpCas9	negative selection	6243217
15911151	15911174	1	+	27260156	CADOES1	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.2757245890208629	[623]	[589,744,713,763]	4	hSpCas9	negative selection	6243218
15872951	15872974	1	-	27260156	EWS502	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.5515746953842302	[759]	[593,518,627,442]	-7	hSpCas9	negative selection	6300211
15873090	15873113	1	+	27260156	EWS502	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.05539201929986476	[556]	[439,646,492,908]	1	hSpCas9	negative selection	6300212
15918956	15918979	1	-	27260156	EWS502	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.3638481264895024	[1628]	[1009,1622,1294,1466]	-6	hSpCas9	negative selection	6300213
15919030	15919053	1	+	27260156	EWS502	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.23956127916830083	[1059]	[1275,1463,1294,1256]	4	hSpCas9	negative selection	6364467
15911229	15911252	1	+	27260156	EWS502	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.27115054993912036	[898]	[792,661,924,778]	-5	hSpCas9	negative selection	6364468
15911151	15911174	1	+	27260156	EWS502	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.05969025039810072	[623]	[571,659,805,734]	1	hSpCas9	negative selection	6364469
15872951	15872974	1	-	27260156	EW8	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2742734930424224	[759]	[543,625,307,595]	-5	hSpCas9	negative selection	6421462
15873090	15873113	1	+	27260156	EW8	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.2398824439047022	[556]	[669,578,331,598]	4	hSpCas9	negative selection	6421463
15918956	15918979	1	-	27260156	EW8	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.0053769247629043004	[1628]	[1365,1472,1291,1136]	0	hSpCas9	negative selection	6421464
15919030	15919053	1	+	27260156	EW8	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3105151057381492	[1059]	[1428,889,866,1144]	5	hSpCas9	negative selection	6485718
15911229	15911252	1	+	27260156	EW8	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.28023171327410745	[898]	[1204,918,901,543]	5	hSpCas9	negative selection	6485719
15911151	15911174	1	+	27260156	EW8	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.2507622246079368	[623]	[488,610,633,652]	4	hSpCas9	negative selection	6485720
15872951	15872974	1	-	27260156	CORL105	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.06819604432016713	[759]	[784,965,1103,896]	1	hSpCas9	negative selection	6542713
15873090	15873113	1	+	27260156	CORL105	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.23881356936628212	[556]	[712,571,972,852]	4	hSpCas9	negative selection	6542714
15918956	15918979	1	-	27260156	CORL105	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.05136879019281637	[1628]	[2123,1870,2036,1888]	0	hSpCas9	negative selection	6542715
15919030	15919053	1	+	27260156	CORL105	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.23476091450121528	[1059]	[1103,1473,1688,1595]	4	hSpCas9	negative selection	6606969
15911229	15911252	1	+	27260156	CORL105	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.1228386478329988	[898]	[1304,1087,1148,1048]	2	hSpCas9	negative selection	6606970
15911151	15911174	1	+	27260156	CORL105	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.36645724455947254	[623]	[855,844,1204,900]	6	hSpCas9	negative selection	6606971
15872951	15872974	1	-	27260156	HS294T	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.4176114609987478	[759]	[184,277,170,251]	-5	hSpCas9	negative selection	6663964
15873090	15873113	1	+	27260156	HS294T	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.29675400481887737	[556]	[394,152,277,213]	4	hSpCas9	negative selection	6663965
15918956	15918979	1	-	27260156	HS294T	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.2336203226010305	[1628]	[487,549,516,600]	-3	hSpCas9	negative selection	6663966
15919030	15919053	1	+	27260156	HS294T	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3445932131340874	[1059]	[434,627,448,582]	4	hSpCas9	negative selection	6728220
15911229	15911252	1	+	27260156	HS294T	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.12113361925610522	[898]	[392,385,407,310]	1	hSpCas9	negative selection	6728221
15911151	15911174	1	+	27260156	HS294T	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.1726464596516608	[623]	[264,185,188,210]	-2	hSpCas9	negative selection	6728222
15872951	15872974	1	-	27260156	HCC44	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2803163252121299	[759]	[679,372,1146,744]	-4	hSpCas9	negative selection	6785215
15873090	15873113	1	+	27260156	HCC44	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.1866894290635483	[556]	[822,542,764,771]	3	hSpCas9	negative selection	6785216
15918956	15918979	1	-	27260156	HCC44	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.8218951414489726	[1628]	[1178,807,1413,874]	-8	hSpCas9	negative selection	6785217
15919030	15919053	1	+	27260156	HCC44	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.08064999817698082	[1059]	[1281,738,1016,1523]	-1	hSpCas9	negative selection	6849471
15911229	15911252	1	+	27260156	HCC44	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.5871258363085563	[898]	[792,571,736,636]	-7	hSpCas9	negative selection	6849472
15911151	15911174	1	+	27260156	HCC44	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.2638497762039458	[623]	[634,666,588,452]	-4	hSpCas9	negative selection	6849473
15872951	15872974	1	-	27260156	G402	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.14873966876769484	[759]	[879,651,771,1024]	-2	hSpCas9	negative selection	6906466
15873090	15873113	1	+	27260156	G402	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.2871197701734246	[556]	[1257,629,787,694]	3	hSpCas9	negative selection	6906467
15918956	15918979	1	-	27260156	G402	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.26625419670468164	[1628]	[1778,1379,2157,1306]	-3	hSpCas9	negative selection	6906468
15919030	15919053	1	+	27260156	G402	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3834127680629169	[1059]	[2304,1285,2059,1181]	5	hSpCas9	negative selection	6970722
15911229	15911252	1	+	27260156	G402	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.4556759213061449	[898]	[677,919,771,814]	-5	hSpCas9	negative selection	6970723
15911151	15911174	1	+	27260156	G402	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.026844084436272786	[623]	[1138,655,567,781]	0	hSpCas9	negative selection	6970724
15872951	15872974	1	-	27260156	L33	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.20320074661519266	[759]	[617,303,403,638]	-5	hSpCas9	negative selection	7027717
15873090	15873113	1	+	27260156	L33	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.08340063342644954	[556]	[595,257,361,558]	1	hSpCas9	negative selection	7027718
15918956	15918979	1	-	27260156	L33	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.11261016065555562	[1628]	[1413,652,901,1584]	-3	hSpCas9	negative selection	7027719
15919030	15919053	1	+	27260156	L33	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.09469445311589686	[1059]	[1063,523,562,1287]	2	hSpCas9	negative selection	7091973
15911229	15911252	1	+	27260156	L33	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.21529142106421806	[898]	[1106,395,688,1003]	5	hSpCas9	negative selection	7091974
15911151	15911174	1	+	27260156	L33	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.024885531578746678	[623]	[659,278,336,574]	0	hSpCas9	negative selection	7091975
15872951	15872974	1	-	27260156	K562	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.59227226100757	[759]	[390,352,737,311]	-6	hSpCas9	negative selection	7148968
15873090	15873113	1	+	27260156	K562	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.0742322156615143	[556]	[488,327,713,352]	-1	hSpCas9	negative selection	7148969
15918956	15918979	1	-	27260156	K562	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.7631817473160776	[1628]	[731,1036,892,752]	-7	hSpCas9	negative selection	7148970
15919030	15919053	1	+	27260156	K562	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3252151307670983	[1059]	[1315,878,1136,1351]	4	hSpCas9	negative selection	7213224
15911229	15911252	1	+	27260156	K562	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.1697874714343306	[898]	[334,420,1406,633]	-2	hSpCas9	negative selection	7213225
15911151	15911174	1	+	27260156	K562	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.5168342189592092	[623]	[348,734,725,1260]	6	hSpCas9	negative selection	7213226
15872951	15872974	1	-	27260156	HT29	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.44003579487450206	[759]	[759,669,602,689]	-7	hSpCas9	negative selection	7270219
15873090	15873113	1	+	27260156	HT29	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.06041034693775987	[556]	[872,634,559,751]	1	hSpCas9	negative selection	7270220
15918956	15918979	1	-	27260156	HT29	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.34691720150316274	[1628]	[1562,1568,1447,1628]	-6	hSpCas9	negative selection	7270221
15919030	15919053	1	+	27260156	HT29	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.06181618930550736	[1059]	[1302,1222,1607,1235]	1	hSpCas9	negative selection	7334475
15911229	15911252	1	+	27260156	HT29	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.358135086522121	[898]	[888,970,837,733]	-6	hSpCas9	negative selection	7334476
15911151	15911174	1	+	27260156	HT29	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.09445453522931718	[623]	[832,980,670,769]	1	hSpCas9	negative selection	7334477
15872951	15872974	1	-	27260156	MHHES1	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.6475789199369714	[759]	[552,569,628,447]	-8	hSpCas9	negative selection	7391470
15873090	15873113	1	+	27260156	MHHES1	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.4108491427939681	[556]	[592,591,402,344]	-6	hSpCas9	negative selection	7391471
15918956	15918979	1	-	27260156	MHHES1	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.780664230008465	[1628]	[1492,1190,1018,695]	-8	hSpCas9	negative selection	7391472
15919030	15919053	1	+	27260156	MHHES1	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.09907576842307853	[1059]	[1360,1393,1076,745]	-2	hSpCas9	negative selection	7455726
15911229	15911252	1	+	27260156	MHHES1	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.4494040280212163	[898]	[926,875,737,500]	-7	hSpCas9	negative selection	7455727
15911151	15911174	1	+	27260156	MHHES1	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.2946325899457453	[623]	[663,524,702,427]	-5	hSpCas9	negative selection	7455728
15872951	15872974	1	-	27260156	MEWO	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2106936846181366	[759]	[833,541,509]	-4	hSpCas9	negative selection	7512721
15873090	15873113	1	+	27260156	MEWO	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.07601837072185691	[556]	[739,493,450]	1	hSpCas9	negative selection	7512722
15918956	15918979	1	-	27260156	MEWO	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.32683478212768646	[1628]	[1074,1182,1359]	-6	hSpCas9	negative selection	7512723
15919030	15919053	1	+	27260156	MEWO	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.1654298575683042	[1059]	[1004,877,792]	-4	hSpCas9	negative selection	7576977
15911229	15911252	1	+	27260156	MEWO	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.12587976317111793	[898]	[1011,553,793]	-3	hSpCas9	negative selection	7576978
15911151	15911174	1	+	27260156	MEWO	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.2444580966322069	[623]	[934,642,543]	5	hSpCas9	negative selection	7576979
15872951	15872974	1	-	27260156	LNCAPCLONEFGC	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.44021673266025263	[759]	[473,546,592,425]	-6	hSpCas9	negative selection	7633972
15873090	15873113	1	+	27260156	LNCAPCLONEFGC	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.004521607506284692	[556]	[470,467,610,492]	0	hSpCas9	negative selection	7633973
15918956	15918979	1	-	27260156	LNCAPCLONEFGC	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.12647065818242376	[1628]	[1221,1095,1508,1621]	-2	hSpCas9	negative selection	7633974
15919030	15919053	1	+	27260156	LNCAPCLONEFGC	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.0479518702097248	[1059]	[905,960,1290,859]	0	hSpCas9	negative selection	7698228
15911229	15911252	1	+	27260156	LNCAPCLONEFGC	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.04147618875798287	[898]	[635,781,755,988]	0	hSpCas9	negative selection	7698229
15911151	15911174	1	+	27260156	LNCAPCLONEFGC	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.10511284367872803	[623]	[331,431,742,636]	-2	hSpCas9	negative selection	7698230
15872951	15872974	1	-	27260156	PANC0327	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.5696672792477468	[759]	[669,491,301,367]	-7	hSpCas9	negative selection	7755223
15873090	15873113	1	+	27260156	PANC0327	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.41552874938693574	[556]	[562,344,668,1094]	6	hSpCas9	negative selection	7755224
15918956	15918979	1	-	27260156	PANC0327	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.1817997660737174	[1628]	[1074,1248,1542,1222]	-3	hSpCas9	negative selection	7755225
15919030	15919053	1	+	27260156	PANC0327	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.2858841381695538	[1059]	[1079,1267,936,1284]	4	hSpCas9	negative selection	7819479
15911229	15911252	1	+	27260156	PANC0327	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.005766215107641082	[898]	[745,1245,599,526]	0	hSpCas9	negative selection	7819480
15911151	15911174	1	+	27260156	PANC0327	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.6484962372675012	[623]	[744,1663,437,514]	8	hSpCas9	negative selection	7819481
15872951	15872974	1	-	27260156	NCIH2009	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.0823445640149314	[759]	[1190,851,1003]	-1	hSpCas9	negative selection	7876474
15873090	15873113	1	+	27260156	NCIH2009	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.2692194746313685	[556]	[1165,833,858]	3	hSpCas9	negative selection	7876475
15918956	15918979	1	-	27260156	NCIH2009	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.09377753975432146	[1628]	[2247,1821,2352]	-1	hSpCas9	negative selection	7876476
15919030	15919053	1	+	27260156	NCIH2009	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.2380610600253803	[1059]	[1846,1686,1723]	3	hSpCas9	negative selection	7940730
15911229	15911252	1	+	27260156	NCIH2009	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.1044168188954433	[898]	[1520,1427,1131]	1	hSpCas9	negative selection	7940731
15911151	15911174	1	+	27260156	NCIH2009	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.4527292846414644	[623]	[1478,921,1237]	6	hSpCas9	negative selection	7940732
15872951	15872974	1	-	27260156	NCIH1373	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.20457683732028653	[759]	[859,985,889,309]	2	hSpCas9	negative selection	7997725
15873090	15873113	1	+	27260156	NCIH1373	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.29091355180163586	[556]	[575,654,348,118]	-3	hSpCas9	negative selection	7997726
15918956	15918979	1	-	27260156	NCIH1373	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.154488570579141	[1628]	[2342,1806,1718,616]	1	hSpCas9	negative selection	7997727
15919030	15919053	1	+	27260156	NCIH1373	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.7763727274291903	[1059]	[1671,1829,2587,522]	7	hSpCas9	negative selection	8061981
15911229	15911252	1	+	27260156	NCIH1373	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.06930363633060654	[898]	[1244,866,1217,244]	0	hSpCas9	negative selection	8061982
15911151	15911174	1	+	27260156	NCIH1373	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.23585381528658184	[623]	[1221,646,833,172]	2	hSpCas9	negative selection	8061983
15872951	15872974	1	-	27260156	PATU8902	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.16043147492939258	[759]	[988,1133,866,792]	-2	hSpCas9	negative selection	8118976
15873090	15873113	1	+	27260156	PATU8902	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.3529381783124068	[556]	[812,771,194,768]	-4	hSpCas9	negative selection	8118977
15918956	15918979	1	-	27260156	PATU8902	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.03556680754533992	[1628]	[2600,2037,2112,2615]	0	hSpCas9	negative selection	8118978
15919030	15919053	1	+	27260156	PATU8902	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.1533418904997339	[1059]	[1478,1719,1454,1992]	1	hSpCas9	negative selection	8183232
15911229	15911252	1	+	27260156	PATU8902	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.20485782992524604	[898]	[1068,1143,1051,1079]	-2	hSpCas9	negative selection	8183233
15911151	15911174	1	+	27260156	PATU8902	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.2905690165266093	[623]	[997,1209,933,1145]	3	hSpCas9	negative selection	8183234
15872951	15872974	1	-	27260156	PANC1	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.6394624994934817	[759]	[815,1359,921,1024]	9	hSpCas9	negative selection	8240227
15873090	15873113	1	+	27260156	PANC1	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.12211763663619196	[556]	[460,713,483,464]	2	hSpCas9	negative selection	8240228
15918956	15918979	1	-	27260156	PANC1	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.25600185545391474	[1628]	[1437,2003,1613,1671]	4	hSpCas9	negative selection	8240229
15919030	15919053	1	+	27260156	PANC1	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3474953086464241	[1059]	[1228,1538,1339,666]	5	hSpCas9	negative selection	8304483
15911229	15911252	1	+	27260156	PANC1	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.31616305158701197	[898]	[830,1290,989,812]	5	hSpCas9	negative selection	8304484
15911151	15911174	1	+	27260156	PANC1	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.8211069917128402	[623]	[952,932,898,977]	9	hSpCas9	negative selection	8304485
15872951	15872974	1	-	27260156	PANC0813	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.3696294251058003	[759]	[1429,946,1136,1124]	6	hSpCas9	negative selection	8361478
15873090	15873113	1	+	27260156	PANC0813	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.3610285058381564	[556]	[1014,780,746,832]	6	hSpCas9	negative selection	8361479
15918956	15918979	1	-	27260156	PANC0813	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.2686815800326956	[1628]	[2408,2107,2556,2161]	4	hSpCas9	negative selection	8361480
15919030	15919053	1	+	27260156	PANC0813	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.43704236713688793	[1059]	[1803,1560,1957,1442]	7	hSpCas9	negative selection	8425734
15911229	15911252	1	+	27260156	PANC0813	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.21056154583434283	[898]	[1328,1400,1213,965]	3	hSpCas9	negative selection	8425735
15911151	15911174	1	+	27260156	PANC0813	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.7081581659779692	[623]	[1638,1093,1319,798]	9	hSpCas9	negative selection	8425736
15872951	15872974	1	-	27260156	RDES	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.5216259595157846	[759]	[588,433,625,820]	-7	hSpCas9	negative selection	8482729
15873090	15873113	1	+	27260156	RDES	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	-0.3095807751204729	[556]	[423,480,581,603]	-5	hSpCas9	negative selection	8482730
15918956	15918979	1	-	27260156	RDES	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.3959349889134218	[1628]	[1068,1486,1483,1732]	-6	hSpCas9	negative selection	8482731
15919030	15919053	1	+	27260156	RDES	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.17233592926247288	[1059]	[1244,1264,1186,1858]	3	hSpCas9	negative selection	8546985
15911229	15911252	1	+	27260156	RDES	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.5699869361464376	[898]	[643,591,702,872]	-7	hSpCas9	negative selection	8546986
15911151	15911174	1	+	27260156	RDES	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.06215574730776707	[623]	[494,730,619,959]	-1	hSpCas9	negative selection	8546987
15872951	15872974	1	-	27260156	PC3	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2613529696632839	[759]	[345,707,1141,594]	-5	hSpCas9	negative selection	8603980
15873090	15873113	1	+	27260156	PC3	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.2406340507920095	[556]	[486,626,995,646]	5	hSpCas9	negative selection	8603981
15918956	15918979	1	-	27260156	PC3	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.30596100198947873	[1628]	[877,1429,2044,1228]	-6	hSpCas9	negative selection	8603982
15919030	15919053	1	+	27260156	PC3	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.14437037798113983	[1059]	[553,975,1387,1170]	-3	hSpCas9	negative selection	8668236
15911229	15911252	1	+	27260156	PC3	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.06131555967159219	[898]	[586,900,909,1091]	-1	hSpCas9	negative selection	8668237
15911151	15911174	1	+	27260156	PC3	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.006461529010719058	[623]	[505,504,1055,580]	0	hSpCas9	negative selection	8668238
15872951	15872974	1	-	27260156	PATU8988T	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.13695390360012072	[759]	[618,678,733,1219]	2	hSpCas9	negative selection	8725231
15873090	15873113	1	+	27260156	PATU8988T	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.005203598425747302	[556]	[478,514,613,549]	0	hSpCas9	negative selection	8725232
15918956	15918979	1	-	27260156	PATU8988T	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.028328872108142722	[1628]	[1670,1938,1439,1386]	0	hSpCas9	negative selection	8725233
15919030	15919053	1	+	27260156	PATU8988T	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.42747425666029404	[1059]	[1512,1198,1586,1174]	7	hSpCas9	negative selection	8789487
15911229	15911252	1	+	27260156	PATU8988T	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.15759855755871233	[898]	[839,836,549,906]	-3	hSpCas9	negative selection	8789488
15911151	15911174	1	+	27260156	PATU8988T	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.560547881221626	[623]	[914,904,956,770]	8	hSpCas9	negative selection	8789489
15872951	15872974	1	-	27260156	T47D	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2355369001888898	[759]	[808,711,733,756]	-5	hSpCas9	negative selection	8846482
15873090	15873113	1	+	27260156	T47D	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.11924493032361982	[556]	[754,646,697,724]	2	hSpCas9	negative selection	8846483
15918956	15918979	1	-	27260156	T47D	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.13936699287828236	[1628]	[1759,1672,1692,1771]	-3	hSpCas9	negative selection	8846484
15919030	15919053	1	+	27260156	T47D	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.2669005311056827	[1059]	[1639,1381,1448,1481]	5	hSpCas9	negative selection	8910738
15911229	15911252	1	+	27260156	T47D	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.08448099803757647	[898]	[1045,910,1016,982]	-2	hSpCas9	negative selection	8910739
15911151	15911174	1	+	27260156	T47D	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.25256258056118025	[623]	[960,840,889,770]	5	hSpCas9	negative selection	8910740
15872951	15872974	1	-	27260156	SU8686	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	0.5596308583214582	[759]	[1018,1239,943,1240]	8	hSpCas9	negative selection	8967733
15873090	15873113	1	+	27260156	SU8686	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.28179864798658716	[556]	[615,508,860,737]	5	hSpCas9	negative selection	8967734
15918956	15918979	1	-	27260156	SU8686	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	0.3256481646956457	[1628]	[1818,1941,1957,2465]	5	hSpCas9	negative selection	8967735
15919030	15919053	1	+	27260156	SU8686	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.3880908584008189	[1059]	[1062,1304,1323,1932]	6	hSpCas9	negative selection	9031989
15911229	15911252	1	+	27260156	SU8686	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	0.12321679801624685	[898]	[838,1115,964,947]	2	hSpCas9	negative selection	9031990
15911151	15911174	1	+	27260156	SU8686	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.5528111599372372	[623]	[715,839,869,1288]	8	hSpCas9	negative selection	9031991
15872951	15872974	1	-	27260156	SKES1	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.8234009147766224	[759]	[551,441,363,376]	-9	hSpCas9	negative selection	9088984
15873090	15873113	1	+	27260156	SKES1	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.06376297933443315	[556]	[662,724,449,516]	1	hSpCas9	negative selection	9088985
15918956	15918979	1	-	27260156	SKES1	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.9437256472184262	[1628]	[730,973,858,809]	-9	hSpCas9	negative selection	9088986
15919030	15919053	1	+	27260156	SKES1	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.08430377000227551	[1059]	[1167,1042,1086,739]	-2	hSpCas9	negative selection	9153240
15911229	15911252	1	+	27260156	SKES1	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.3583467746935355	[898]	[581,859,638,711]	-7	hSpCas9	negative selection	9153241
15911151	15911174	1	+	27260156	SKES1	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.3324880384827688	[623]	[512,392,596,461]	-6	hSpCas9	negative selection	9153242
15872951	15872974	1	-	27260156	TOV112D	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.05815706709623203	[759]	[498,1292,665,587]	-1	hSpCas9	negative selection	9210235
15873090	15873113	1	+	27260156	TOV112D	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.14127090347156823	[556]	[777,554,623,504]	2	hSpCas9	negative selection	9210236
15918956	15918979	1	-	27260156	TOV112D	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.32507064860388835	[1628]	[1334,1842,1255,919]	-6	hSpCas9	negative selection	9210237
15919030	15919053	1	+	27260156	TOV112D	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.14063485399776554	[1059]	[1226,1685,759,1138]	2	hSpCas9	negative selection	9274491
15911229	15911252	1	+	27260156	TOV112D	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.1305102657234677	[898]	[591,1345,741,720]	-3	hSpCas9	negative selection	9274492
15911151	15911174	1	+	27260156	TOV112D	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.04280288714367836	[623]	[782,532,542,697]	0	hSpCas9	negative selection	9274493
15872951	15872974	1	-	27260156	TC71	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2485808606964912	[759]	[551,715,693,789]	-6	hSpCas9	negative selection	9331486
15873090	15873113	1	+	27260156	TC71	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.22381267190480514	[556]	[873,638,617,653]	5	hSpCas9	negative selection	9331487
15918956	15918979	1	-	27260156	TC71	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.2506025535722154	[1628]	[1182,1528,1450,1730]	-6	hSpCas9	negative selection	9331488
15919030	15919053	1	+	27260156	TC71	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	0.0313368082113461	[1059]	[963,1346,973,1383]	0	hSpCas9	negative selection	9395742
15911229	15911252	1	+	27260156	TC71	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.10540192377980828	[898]	[877,800,923,984]	-3	hSpCas9	negative selection	9395743
15911151	15911174	1	+	27260156	TC71	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	-0.1259510341202173	[623]	[634,564,612,639]	-3	hSpCas9	negative selection	9395744
15872951	15872974	1	-	27260156	TC32	viability	GTTCATTATAATCCGTGCGTAGG	SPEN	ENSG00000065526	-0.2781567892361849	[759]	[526,518,700,627]	-5	hSpCas9	negative selection	9452737
15873090	15873113	1	+	27260156	TC32	viability	CCGTCACTTCATGCACGAGAAGG	SPEN	ENSG00000065526	0.1000539349166677	[556]	[338,594,704,612]	1	hSpCas9	negative selection	9452738
15918956	15918979	1	-	27260156	TC32	viability	TATTGCAGAAACGCATACTGAGG	SPEN	ENSG00000065526	-0.35132393596457945	[1628]	[1062,884,1617,1382]	-6	hSpCas9	negative selection	9452739
15919030	15919053	1	+	27260156	TC32	viability	TCTTGGAAATAATCGCCTCAAGG	SPEN	ENSG00000065526	-0.06657866460563855	[1059]	[966,665,1183,1084]	-1	hSpCas9	negative selection	9516993
15911229	15911252	1	+	27260156	TC32	viability	AAAGCCTTGACTGCATCAAAAGG	SPEN	ENSG00000065526	-0.10973392610538935	[898]	[721,688,897,839]	-2	hSpCas9	negative selection	9516994
15911151	15911174	1	+	27260156	TC32	viability	GTAACTTCAGTGCAGATACATGG	SPEN	ENSG00000065526	0.024462328879602313	[623]	[806,330,662,635]	0	hSpCas9	negative selection	9516995
15848063	15848086	1	+	27869803	HPAFII	viability after 27 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.5877951072627745	[1307]	[552,377,NaN]	-4	hSpCas9	negative selection	9530140
15873087	15873110	1	-	27869803	HPAFII	viability after 27 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9530152
15876239	15876262	1	+	27869803	HPAFII	viability after 27 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.3275646798838018	[566]	[290,192,NaN]	-2	hSpCas9	negative selection	9530153
15909355	15909378	1	-	27869803	HPAFII	viability after 27 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.4645133150219006	[297]	[177,247,NaN]	4	hSpCas9	negative selection	9530171
15911198	15911221	1	+	27869803	HPAFII	viability after 27 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	1.3450575883188196	[93]	[46,190,NaN]	9	hSpCas9	negative selection	9530172
15916243	15916266	1	-	27869803	HPAFII	viability after 27 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.5974318526833726	[271]	[169,254,NaN]	5	hSpCas9	negative selection	9530174
15848063	15848086	1	+	27869803	HPAFII	viability after 15 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.3250869611013094	[1307]	[1517,875,NaN]	-4	hSpCas9	negative selection	9612589
15873087	15873110	1	-	27869803	HPAFII	viability after 15 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9612601
15876239	15876262	1	+	27869803	HPAFII	viability after 15 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.22397165157961296	[566]	[493,538,NaN]	-3	hSpCas9	negative selection	9612602
15909355	15909378	1	-	27869803	HPAFII	viability after 15 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.22932166690562475	[297]	[287,263,NaN]	-3	hSpCas9	negative selection	9612620
15911198	15911221	1	+	27869803	HPAFII	viability after 15 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	0.544244280451284	[93]	[179,126,NaN]	6	hSpCas9	negative selection	9612621
15916243	15916266	1	-	27869803	HPAFII	viability after 15 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.3733250558301694	[271]	[316,416,NaN]	4	hSpCas9	negative selection	9612623
15848063	15848086	1	+	27869803	ASPC1	viability after 36 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.0826233949033286	[2739]	[1428,601,763]	-1	hSpCas9	negative selection	9695038
15873087	15873110	1	-	27869803	ASPC1	viability after 36 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	-0.6382060903295733	[371]	[24,34,161]	-6	hSpCas9	negative selection	9695050
15876239	15876262	1	+	27869803	ASPC1	viability after 36 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.0253351555805299	[1194]	[901,207,256]	0	hSpCas9	negative selection	9695051
15909355	15909378	1	-	27869803	ASPC1	viability after 36 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.5985360792222207	[777]	[832,317,184]	6	hSpCas9	negative selection	9695069
15911198	15911221	1	+	27869803	ASPC1	viability after 36 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.03515473785579637	[217]	[150,30,53]	0	hSpCas9	negative selection	9695070
15916243	15916266	1	-	27869803	ASPC1	viability after 36 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.6391590876768071	[657]	[311,98,68]	-6	hSpCas9	negative selection	9695072
15848063	15848086	1	+	27869803	PATU8988S	viability after 35 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-1.0308039703401315	[2519]	[384,608,NaN]	-7	hSpCas9	negative selection	9777487
15873087	15873110	1	-	27869803	PATU8988S	viability after 35 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	-1.3825012253413131	[345]	[30,75,NaN]	-8	hSpCas9	negative selection	9777499
15876239	15876262	1	+	27869803	PATU8988S	viability after 35 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.1324247060893653	[1171]	[692,340,NaN]	1	hSpCas9	negative selection	9777500
15909355	15909378	1	-	27869803	PATU8988S	viability after 35 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.2942202656672326	[635]	[161,255,NaN]	-3	hSpCas9	negative selection	9777518
15911198	15911221	1	+	27869803	PATU8988S	viability after 35 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-0.8074502898853426	[229]	[21,83,NaN]	-7	hSpCas9	negative selection	9777519
15916243	15916266	1	-	27869803	PATU8988S	viability after 35 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-0.9202960369851687	[493]	[161,47,NaN]	-7	hSpCas9	negative selection	9777521
15848063	15848086	1	+	27869803	PATU8988S	viability after 31 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.9329016563258454	[2519]	[407,676,NaN]	-7	hSpCas9	negative selection	9859936
15873087	15873110	1	-	27869803	PATU8988S	viability after 31 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	-1.0214681456102341	[345]	[85,44,NaN]	-7	hSpCas9	negative selection	9859948
15876239	15876262	1	+	27869803	PATU8988S	viability after 31 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	0.2718068226432713	[1171]	[627,482,NaN]	3	hSpCas9	negative selection	9859949
15909355	15909378	1	-	27869803	PATU8988S	viability after 31 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	-0.028083351615740326	[635]	[209,297,NaN]	0	hSpCas9	negative selection	9859967
15911198	15911221	1	+	27869803	PATU8988S	viability after 31 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	-1.443540678112111	[229]	[27,40,NaN]	-8	hSpCas9	negative selection	9859968
15916243	15916266	1	-	27869803	PATU8988S	viability after 31 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	-2.0085260867032675	[493]	[22,81,NaN]	-9	hSpCas9	negative selection	9859970
15848063	15848086	1	+	27869803	HPAFII	viability after 35 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.593474825086292	[1307]	[491,378,NaN]	-4	hSpCas9	negative selection	9942385
15873087	15873110	1	-	27869803	HPAFII	viability after 35 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	9942397
15876239	15876262	1	+	27869803	HPAFII	viability after 35 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.22494497786113798	[566]	[151,350,NaN]	-1	hSpCas9	negative selection	9942398
15909355	15909378	1	-	27869803	HPAFII	viability after 35 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.9646081270103102	[297]	[173,429,NaN]	6	hSpCas9	negative selection	9942416
15911198	15911221	1	+	27869803	HPAFII	viability after 35 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	1.9647257766043	[93]	[38,350,NaN]	9	hSpCas9	negative selection	9942417
15916243	15916266	1	-	27869803	HPAFII	viability after 35 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	1.1538014193300403	[271]	[240,379,NaN]	7	hSpCas9	negative selection	9942419
15848063	15848086	1	+	27869803	HPAFII	viability after 31 days	CCAGCATGGTCCGGGAAACCAGG	SPEN	ENSG00000065526	-0.6218221553643082	[1307]	[488,463,NaN]	-4	hSpCas9	negative selection	10024834
15873087	15873110	1	-	27869803	HPAFII	viability after 31 days	TCTCGTGCATGAAGTGACGGTGG	SPEN	ENSG00000065526	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10024846
15876239	15876262	1	+	27869803	HPAFII	viability after 31 days	GCCTATGGACACCATGAACGGGG	SPEN	ENSG00000065526	-0.05217531248139817	[566]	[248,369,NaN]	0	hSpCas9	negative selection	10024847
15909355	15909378	1	-	27869803	HPAFII	viability after 31 days	GCAGACTGAACTGATCGAGCTGG	SPEN	ENSG00000065526	0.7913374232339028	[297]	[209,375,NaN]	6	hSpCas9	negative selection	10024865
15911198	15911221	1	+	27869803	HPAFII	viability after 31 days	GGTATTCTTTCGGCAGCAAGAGG	SPEN	ENSG00000065526	1.830188500412857	[93]	[21,367,NaN]	9	hSpCas9	negative selection	10024866
15916243	15916266	1	-	27869803	HPAFII	viability after 31 days	AGCGCTGGAAGATGTTGCGAAGG	SPEN	ENSG00000065526	0.6863687872885742	[271]	[181,314,NaN]	5	hSpCas9	negative selection	10024868
15920933	15920956	1	+	28162770	P31FUJ	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.44111944053910357	[118]	[102]	-4	hSpCas9	negative selection	10241862
15932070	15932093	1	+	28162770	P31FUJ	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.329493403618256	[940]	[439]	-7	hSpCas9	negative selection	10241863
15929997	15930020	1	+	28162770	P31FUJ	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-1.9697677985805846	[69]	[20]	-8	hSpCas9	negative selection	10241864
15936217	15936240	1	-	28162770	P31FUJ	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.7940644014383034	[132]	[270]	8	hSpCas9	negative selection	10241865
15872852	15872875	1	+	28162770	P31FUJ	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.3125293968851124	[92]	[21]	-8	hSpCas9	negative selection	10241866
15872878	15872901	1	-	28162770	P31FUJ	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.24401149245115494	[119]	[166]	2	hSpCas9	negative selection	10241867
15872939	15872962	1	+	28162770	P31FUJ	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.20777038697160288	[265]	[360]	2	hSpCas9	negative selection	10241868
15873039	15873062	1	+	28162770	P31FUJ	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.2637223316391937	[184]	[260]	3	hSpCas9	negative selection	10241869
15928378	15928401	1	+	28162770	P31FUJ	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.17309595829011082	[212]	[221]	-2	hSpCas9	negative selection	10241870
15930869	15930892	1	+	28162770	P31FUJ	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.6113138276681085	[64]	[49]	-5	hSpCas9	negative selection	10241871
15920933	15920956	1	+	28162770	TF1	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10411228
15932070	15932093	1	+	28162770	TF1	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10411229
15929997	15930020	1	+	28162770	TF1	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10411230
15936217	15936240	1	-	28162770	TF1	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10411231
15872852	15872875	1	+	28162770	TF1	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10411232
15872878	15872901	1	-	28162770	TF1	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10411233
15872939	15872962	1	+	28162770	TF1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10411234
15873039	15873062	1	+	28162770	TF1	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10411235
15928378	15928401	1	+	28162770	TF1	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10411236
15930869	15930892	1	+	28162770	TF1	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10411237
15920933	15920956	1	+	28162770	SKM1	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	0.31044859800164415	[25]	[56]	3	hSpCas9	negative selection	10580594
15932070	15932093	1	+	28162770	SKM1	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.1781455082472807	[191]	[299]	-1	hSpCas9	negative selection	10580595
15929997	15930020	1	+	28162770	SKM1	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.0630097975258006	[12]	[21]	0	hSpCas9	negative selection	10580596
15936217	15936240	1	-	28162770	SKM1	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	1.9922068950766612	[29]	[210]	9	hSpCas9	negative selection	10580597
15872852	15872875	1	+	28162770	SKM1	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-1.620367836852355	[39]	[22]	-8	hSpCas9	negative selection	10580598
15872878	15872901	1	-	28162770	SKM1	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.7264349266740366	[39]	[116]	7	hSpCas9	negative selection	10580599
15872939	15872962	1	+	28162770	SKM1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.7818198299504666	[75]	[230]	7	hSpCas9	negative selection	10580600
15873039	15873062	1	+	28162770	SKM1	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.5347197459415344	[58]	[71]	-4	hSpCas9	negative selection	10580601
15928378	15928401	1	+	28162770	SKM1	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	0.39030190569085865	[40]	[94]	4	hSpCas9	negative selection	10580602
15930869	15930892	1	+	28162770	SKM1	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	1.4609322652494932	[14]	[72]	9	hSpCas9	negative selection	10580603
15920933	15920956	1	+	28162770	SKM1	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	0.31044859800164415	[25]	[56]	3	hSpCas9	negative selection	10749960
15932070	15932093	1	+	28162770	SKM1	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.1781455082472807	[191]	[299]	-1	hSpCas9	negative selection	10749961
15929997	15930020	1	+	28162770	SKM1	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.0630097975258006	[12]	[21]	0	hSpCas9	negative selection	10749962
15936217	15936240	1	-	28162770	SKM1	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	1.9922068950766612	[29]	[210]	9	hSpCas9	negative selection	10749963
15872852	15872875	1	+	28162770	SKM1	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-1.620367836852355	[39]	[22]	-8	hSpCas9	negative selection	10749964
15872878	15872901	1	-	28162770	SKM1	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.7264349266740366	[39]	[116]	7	hSpCas9	negative selection	10749965
15872939	15872962	1	+	28162770	SKM1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.7818198299504666	[75]	[230]	7	hSpCas9	negative selection	10749966
15873039	15873062	1	+	28162770	SKM1	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.5347197459415344	[58]	[71]	-4	hSpCas9	negative selection	10749967
15928378	15928401	1	+	28162770	SKM1	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	0.39030190569085865	[40]	[94]	4	hSpCas9	negative selection	10749968
15930869	15930892	1	+	28162770	SKM1	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	1.4609322652494932	[14]	[72]	9	hSpCas9	negative selection	10749969
15920933	15920956	1	+	28162770	PL21	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	0.1382118653461184	[118]	[56]	1	hSpCas9	negative selection	10919326
15932070	15932093	1	+	28162770	PL21	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	0.17386028969047107	[553]	[271]	1	hSpCas9	negative selection	10919327
15929997	15930020	1	+	28162770	PL21	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-3.9697853869529927	[35]	[0]	-9	hSpCas9	negative selection	10919328
15936217	15936240	1	-	28162770	PL21	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.5364230023537526	[159]	[100]	5	hSpCas9	negative selection	10919329
15872852	15872875	1	+	28162770	PL21	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-1.7236247996835945	[128]	[16]	-8	hSpCas9	negative selection	10919330
15872878	15872901	1	-	28162770	PL21	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	1.3628691145274285	[133]	[149]	9	hSpCas9	negative selection	10919331
15872939	15872962	1	+	28162770	PL21	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.23781003245537496	[188]	[96]	2	hSpCas9	negative selection	10919332
15873039	15873062	1	+	28162770	PL21	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.7248016049426621	[113]	[81]	6	hSpCas9	negative selection	10919333
15928378	15928401	1	+	28162770	PL21	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	1.1184558168956122	[108]	[102]	8	hSpCas9	negative selection	10919334
15930869	15930892	1	+	28162770	PL21	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	1.3700646159316325	[47]	[53]	9	hSpCas9	negative selection	10919335
15920933	15920956	1	+	28162770	P31FUJ	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.44111944053910357	[118]	[102]	-4	hSpCas9	negative selection	11088692
15932070	15932093	1	+	28162770	P31FUJ	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.329493403618256	[940]	[439]	-7	hSpCas9	negative selection	11088693
15929997	15930020	1	+	28162770	P31FUJ	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-1.9697677985805846	[69]	[20]	-8	hSpCas9	negative selection	11088694
15936217	15936240	1	-	28162770	P31FUJ	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.7940644014383034	[132]	[270]	8	hSpCas9	negative selection	11088695
15872852	15872875	1	+	28162770	P31FUJ	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.3125293968851124	[92]	[21]	-8	hSpCas9	negative selection	11088696
15872878	15872901	1	-	28162770	P31FUJ	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.24401149245115494	[119]	[166]	2	hSpCas9	negative selection	11088697
15872939	15872962	1	+	28162770	P31FUJ	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.20777038697160288	[265]	[360]	2	hSpCas9	negative selection	11088698
15873039	15873062	1	+	28162770	P31FUJ	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.2637223316391937	[184]	[260]	3	hSpCas9	negative selection	11088699
15928378	15928401	1	+	28162770	P31FUJ	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.17309595829011082	[212]	[221]	-2	hSpCas9	negative selection	11088700
15930869	15930892	1	+	28162770	P31FUJ	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.6113138276681085	[64]	[49]	-5	hSpCas9	negative selection	11088701
15920933	15920956	1	+	28162770	OCIAML5	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.8135924230493614	[73]	[75]	-5	hSpCas9	negative selection	11258058
15932070	15932093	1	+	28162770	OCIAML5	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.043884178155152	[497]	[435]	-6	hSpCas9	negative selection	11258059
15929997	15930020	1	+	28162770	OCIAML5	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-1.4800977934770394	[16]	[10]	-7	hSpCas9	negative selection	11258060
15936217	15936240	1	-	28162770	OCIAML5	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	-0.20607463674528118	[107]	[168]	-1	hSpCas9	negative selection	11258061
15872852	15872875	1	+	28162770	OCIAML5	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-3.3013739722275863	[70]	[12]	-9	hSpCas9	negative selection	11258062
15872878	15872901	1	-	28162770	OCIAML5	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.3028190311141744	[74]	[166]	2	hSpCas9	negative selection	11258063
15872939	15872962	1	+	28162770	OCIAML5	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.18051763820759414	[196]	[402]	1	hSpCas9	negative selection	11258064
15873039	15873062	1	+	28162770	OCIAML5	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.42035033043852277	[85]	[115]	-3	hSpCas9	negative selection	11258065
15928378	15928401	1	+	28162770	OCIAML5	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.77806598942022	[75]	[79]	-5	hSpCas9	negative selection	11258066
15930869	15930892	1	+	28162770	OCIAML5	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-3.552506289005089	[64]	[9]	-9	hSpCas9	negative selection	11258067
15920933	15920956	1	+	28162770	EOL1	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	1.4613737512474207	[192]	[279]	9	hSpCas9	negative selection	11427424
15932070	15932093	1	+	28162770	EOL1	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.09446034319654961	[763]	[376]	0	hSpCas9	negative selection	11427425
15929997	15930020	1	+	28162770	EOL1	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	0.09857717134558341	[77]	[43]	0	hSpCas9	negative selection	11427426
15936217	15936240	1	-	28162770	EOL1	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	1.2622002187509134	[291]	[368]	9	hSpCas9	negative selection	11427427
15872852	15872875	1	+	28162770	EOL1	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-5.231956714109456	[213]	[2]	-9	hSpCas9	negative selection	11427428
15872878	15872901	1	-	28162770	EOL1	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.3871747293676385	[163]	[112]	3	hSpCas9	negative selection	11427429
15872939	15872962	1	+	28162770	EOL1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.26605623542741297	[321]	[203]	2	hSpCas9	negative selection	11427430
15873039	15873062	1	+	28162770	EOL1	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.7111441334613413	[159]	[137]	6	hSpCas9	negative selection	11427431
15928378	15928401	1	+	28162770	EOL1	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-1.6950608719575129	[294]	[47]	-8	hSpCas9	negative selection	11427432
15930869	15930892	1	+	28162770	EOL1	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-1.2129557521794	[65]	[14]	-7	hSpCas9	negative selection	11427433
15920933	15920956	1	+	28162770	MOLM13	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.27554570795118505	[148]	[88]	-2	hSpCas9	negative selection	11596790
15932070	15932093	1	+	28162770	MOLM13	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.1977609647421383	[716]	[225]	-6	hSpCas9	negative selection	11596791
15929997	15930020	1	+	28162770	MOLM13	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.6195734597057607	[84]	[39]	-4	hSpCas9	negative selection	11596792
15936217	15936240	1	-	28162770	MOLM13	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	1.0845607419930734	[194]	[298]	8	hSpCas9	negative selection	11596793
15872852	15872875	1	+	28162770	MOLM13	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-6.7512791389175835	[148]	[0]	-9	hSpCas9	negative selection	11596794
15872878	15872901	1	-	28162770	MOLM13	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.6387300891686263	[174]	[196]	5	hSpCas9	negative selection	11596795
15872939	15872962	1	+	28162770	MOLM13	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.5455687453664543	[234]	[247]	4	hSpCas9	negative selection	11596796
15873039	15873062	1	+	28162770	MOLM13	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.9773483555099641	[176]	[64]	-5	hSpCas9	negative selection	11596797
15928378	15928401	1	+	28162770	MOLM13	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.2341125403667968	[230]	[141]	-1	hSpCas9	negative selection	11596798
15930869	15930892	1	+	28162770	MOLM13	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-0.63746361860165	[70]	[32]	-4	hSpCas9	negative selection	11596799
15920933	15920956	1	+	28162770	HEL	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	0.3906755439875664	[130]	[109]	3	hSpCas9	negative selection	11766156
15932070	15932093	1	+	28162770	HEL	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.846646008738568	[729]	[129]	-7	hSpCas9	negative selection	11766157
15929997	15930020	1	+	28162770	HEL	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	0.6427388320003571	[38]	[38]	5	hSpCas9	negative selection	11766158
15936217	15936240	1	-	28162770	HEL	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.49351282322588064	[172]	[155]	4	hSpCas9	negative selection	11766159
15872852	15872875	1	+	28162770	HEL	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.679189262887005	[169]	[16]	-8	hSpCas9	negative selection	11766160
15872878	15872901	1	-	28162770	HEL	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	1.508288632227976	[117]	[214]	9	hSpCas9	negative selection	11766161
15872939	15872962	1	+	28162770	HEL	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.997403713299719	[243]	[311]	8	hSpCas9	negative selection	11766162
15873039	15873062	1	+	28162770	HEL	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.8475867945827242	[176]	[62]	-5	hSpCas9	negative selection	11766163
15928378	15928401	1	+	28162770	HEL	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.1686516032924038	[178]	[101]	-1	hSpCas9	negative selection	11766164
15930869	15930892	1	+	28162770	HEL	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	0.3083197929297976	[57]	[45]	2	hSpCas9	negative selection	11766165
15920933	15920956	1	+	28162770	MV411	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	0.00642945127898048	[129]	[109]	0	hSpCas9	negative selection	11935522
15932070	15932093	1	+	28162770	MV411	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-1.1675999484960684	[631]	[236]	-6	hSpCas9	negative selection	11935523
15929997	15930020	1	+	28162770	MV411	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.296882965441035	[69]	[47]	-2	hSpCas9	negative selection	11935524
15936217	15936240	1	-	28162770	MV411	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.3673470145179719	[149]	[162]	3	hSpCas9	negative selection	11935525
15872852	15872875	1	+	28162770	MV411	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-3.3508217725518388	[108]	[8]	-9	hSpCas9	negative selection	11935526
15872878	15872901	1	-	28162770	MV411	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	0.39658099008858466	[100]	[111]	3	hSpCas9	negative selection	11935527
15872939	15872962	1	+	28162770	MV411	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	0.6049895554008591	[191]	[245]	5	hSpCas9	negative selection	11935528
15873039	15873062	1	+	28162770	MV411	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	0.8694893702391517	[127]	[196]	7	hSpCas9	negative selection	11935529
15928378	15928401	1	+	28162770	MV411	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-1.404639145796918	[175]	[55]	-7	hSpCas9	negative selection	11935530
15930869	15930892	1	+	28162770	MV411	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	2.192989766760399	[26]	[103]	9	hSpCas9	negative selection	11935531
15920933	15920956	1	+	28162770	MONOMAC1	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.598399409441321	[69]	[52]	-5	hSpCas9	negative selection	12104888
15932070	15932093	1	+	28162770	MONOMAC1	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.06331248733281258	[277]	[304]	0	hSpCas9	negative selection	12104889
15929997	15930020	1	+	28162770	MONOMAC1	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	0.1655332323251546	[20]	[26]	1	hSpCas9	negative selection	12104890
15936217	15936240	1	-	28162770	MONOMAC1	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.040002350241295614	[83]	[98]	0	hSpCas9	negative selection	12104891
15872852	15872875	1	+	28162770	MONOMAC1	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-1.9132438810589627	[68]	[20]	-8	hSpCas9	negative selection	12104892
15872878	15872901	1	-	28162770	MONOMAC1	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	-1.3896819250019499	[47]	[20]	-8	hSpCas9	negative selection	12104893
15872939	15872962	1	+	28162770	MONOMAC1	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-0.598242073158828	[172]	[130]	-5	hSpCas9	negative selection	12104894
15873039	15873062	1	+	28162770	MONOMAC1	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.8909337193338738	[109]	[67]	-6	hSpCas9	negative selection	12104895
15928378	15928401	1	+	28162770	MONOMAC1	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-0.29189603340099474	[109]	[102]	-3	hSpCas9	negative selection	12104896
15930869	15930892	1	+	28162770	MONOMAC1	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-1.3345403708094885	[21]	[9]	-7	hSpCas9	negative selection	12104897
15920933	15920956	1	+	28162770	OCIAML2	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-1.0474183945176172	[21]	[58]	-6	hSpCas9	negative selection	12274254
15932070	15932093	1	+	28162770	OCIAML2	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.32176643932767846	[91]	[407]	-3	hSpCas9	negative selection	12274255
15929997	15930020	1	+	28162770	OCIAML2	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-1.400240497350763	[9]	[20]	-7	hSpCas9	negative selection	12274256
15936217	15936240	1	-	28162770	OCIAML2	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.5882638638114074	[26]	[224]	6	hSpCas9	negative selection	12274257
15872852	15872875	1	+	28162770	OCIAML2	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-4.586107042662097	[25]	[5]	-9	hSpCas9	negative selection	12274258
15872878	15872901	1	-	28162770	OCIAML2	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	-1.553091985434134	[17]	[33]	-7	hSpCas9	negative selection	12274259
15872939	15872962	1	+	28162770	OCIAML2	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-0.24412129543348154	[24]	[116]	-2	hSpCas9	negative selection	12274260
15873039	15873062	1	+	28162770	OCIAML2	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-0.055592325963317424	[23]	[127]	0	hSpCas9	negative selection	12274261
15928378	15928401	1	+	28162770	OCIAML2	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-2.18683685924157	[22]	[27]	-8	hSpCas9	negative selection	12274262
15930869	15930892	1	+	28162770	OCIAML2	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	-2.4706298252421615	[5]	[5]	-8	hSpCas9	negative selection	12274263
15920933	15920956	1	+	28162770	OCIAML3	viability	GCAGCTGTAAAAGAGACCAAAGG	SPEN	ENSG00000065526	-0.6814704815745023	[33]	[63]	-5	hSpCas9	negative selection	12443620
15932070	15932093	1	+	28162770	OCIAML3	viability	GTTCCCACCACCCCTCGGAGGGG	SPEN	ENSG00000065526	-0.025439577853675566	[176]	[524]	0	hSpCas9	negative selection	12443621
15929997	15930020	1	+	28162770	OCIAML3	viability	GAAGATTCTGAAAGGACTGGTGG	SPEN	ENSG00000065526	-0.3209891459177472	[11]	[28]	-3	hSpCas9	negative selection	12443622
15936217	15936240	1	-	28162770	OCIAML3	viability	CAGGCCAACAGAGGAAGCGGCGG	SPEN	ENSG00000065526	0.5641401933417955	[40]	[182]	5	hSpCas9	negative selection	12443623
15872852	15872875	1	+	28162770	OCIAML3	viability	GAGGGGATCTGAAGGAGGAGTGG	SPEN	ENSG00000065526	-2.594007640324163	[35]	[17]	-9	hSpCas9	negative selection	12443624
15872878	15872901	1	-	28162770	OCIAML3	viability	GATGTCCACAAAATCCACAAAGG	SPEN	ENSG00000065526	-0.47371340660645145	[22]	[49]	-4	hSpCas9	negative selection	12443625
15872939	15872962	1	+	28162770	OCIAML3	viability	GGGTGACAGAGACCTACGCACGG	SPEN	ENSG00000065526	-2.009045139603007	[59]	[44]	-8	hSpCas9	negative selection	12443626
15873039	15873062	1	+	28162770	OCIAML3	viability	GAGGTTTCTGGGTTCAGAGGAGG	SPEN	ENSG00000065526	-1.1085808131539214	[49]	[69]	-7	hSpCas9	negative selection	12443627
15928378	15928401	1	+	28162770	OCIAML3	viability	GGGACAGAGACCATGAGAGGAGG	SPEN	ENSG00000065526	-2.0503859349839066	[58]	[42]	-8	hSpCas9	negative selection	12443628
15930869	15930892	1	+	28162770	OCIAML3	viability	GCAGCATCTAGAGAGAAAAGAGG	SPEN	ENSG00000065526	1.1608798618393055	[7]	[53]	8	hSpCas9	negative selection	12443629