Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 124976
• Symbol: SPNS2
• Description: SPNS lysolipid transporter 2, sphingosine-1-phosphate

DataSource: http://genomecrispr.dkfz.de/#!/results/SPNS2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4525159	4525182	17	-	26472758	Jiyoye	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.658913808951899	[133]	[0]	-9	hSpCas9	negative selection	155442
4536406	4536429	17	-	26472758	Jiyoye	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	3.930737337562886	[1]	[22]	9	hSpCas9	negative selection	155443
4499358	4499381	17	-	26472758	Jiyoye	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-1.1163865745511394	[22]	[7]	-6	hSpCas9	negative selection	155444
4499392	4499415	17	+	26472758	Jiyoye	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.21431299524039682	[39]	[25]	-1	hSpCas9	negative selection	155445
4532977	4533000	17	-	26472758	Jiyoye	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.38164028939873584	[170]	[167]	3	hSpCas9	negative selection	155446
4533033	4533056	17	-	26472758	Jiyoye	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.9229068804041902	[248]	[355]	6	hSpCas9	negative selection	155447
4533314	4533337	17	+	26472758	Jiyoye	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.41448737723561424	[75]	[42]	-3	hSpCas9	negative selection	155448
4533343	4533366	17	-	26472758	Jiyoye	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.2008707323283241	[188]	[123]	-1	hSpCas9	negative selection	155449
4533377	4533400	17	-	26472758	Jiyoye	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.9376900982046531	[62]	[90]	6	hSpCas9	negative selection	155450
4536381	4536404	17	-	26472758	Jiyoye	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	0.809273825077219	[55]	[73]	5	hSpCas9	negative selection	155451
4525159	4525182	17	-	26472758	KBM7	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-4.565479682671704	[538,510]	[1,17]	-9	hSpCas9	negative selection	346560
4536406	4536429	17	-	26472758	KBM7	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.10790061717001187	[44,152]	[20,81]	1	hSpCas9	negative selection	346561
4499358	4499381	17	-	26472758	KBM7	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.7605561251717252	[79,45]	[5,26]	-6	hSpCas9	negative selection	346562
4499392	4499415	17	+	26472758	KBM7	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	1.3254851308555156	[136,88]	[226,44]	9	hSpCas9	negative selection	346563
4532977	4533000	17	-	26472758	KBM7	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-0.12571854179711317	[801,566]	[399,193]	-1	hSpCas9	negative selection	346564
4533033	4533056	17	-	26472758	KBM7	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.008347945888446118	[1252,1042]	[474,598]	0	hSpCas9	negative selection	346565
4533314	4533337	17	+	26472758	KBM7	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.018773188278206204	[520,343]	[160,239]	0	hSpCas9	negative selection	346566
4533343	4533366	17	-	26472758	KBM7	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.5187507408426264	[469,549]	[234,448]	5	hSpCas9	negative selection	346567
4533377	4533400	17	-	26472758	KBM7	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	-0.053005627244550046	[729,783]	[392,303]	0	hSpCas9	negative selection	346568
4536381	4536404	17	-	26472758	KBM7	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.1209626559227876	[279,516]	[208,150]	-1	hSpCas9	negative selection	346569
4525159	4525182	17	-	26472758	Raji	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-4.208520771885993	[238]	[2]	-9	hSpCas9	negative selection	537678
4536406	4536429	17	-	26472758	Raji	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-0.21454455951376272	[104]	[20]	-2	hSpCas9	negative selection	537679
4499358	4499381	17	-	26472758	Raji	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.874469117916141	[78]	[9]	-6	hSpCas9	negative selection	537680
4499392	4499415	17	+	26472758	Raji	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	1.8025289538451787	[20]	[16]	9	hSpCas9	negative selection	537681
4532977	4533000	17	-	26472758	Raji	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	1.1625250895660606	[307]	[159]	8	hSpCas9	negative selection	537682
4533033	4533056	17	-	26472758	Raji	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.07535515179647634	[621]	[136]	0	hSpCas9	negative selection	537683
4533314	4533337	17	+	26472758	Raji	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.4218170937140374	[192]	[59]	4	hSpCas9	negative selection	537684
4533343	4533366	17	-	26472758	Raji	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.5362268341774736	[207]	[69]	5	hSpCas9	negative selection	537685
4533377	4533400	17	-	26472758	Raji	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	-0.6028151492298213	[444]	[67]	-5	hSpCas9	negative selection	537686
4536381	4536404	17	-	26472758	Raji	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.7651555554441422	[248]	[33]	-5	hSpCas9	negative selection	537687
4525159	4525182	17	-	26472758	K562	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.9682802974661575	[444]	[2]	-9	hSpCas9	negative selection	728796
4536406	4536429	17	-	26472758	K562	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.17932369944456217	[135]	[129]	1	hSpCas9	negative selection	728797
4499358	4499381	17	-	26472758	K562	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.33188156891678644	[79]	[84]	2	hSpCas9	negative selection	728798
4499392	4499415	17	+	26472758	K562	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.44363726601881304	[86]	[53]	-3	hSpCas9	negative selection	728799
4532977	4533000	17	-	26472758	K562	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.42347474086088766	[559]	[633]	3	hSpCas9	negative selection	728800
4533033	4533056	17	-	26472758	K562	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.14385476109916318	[801]	[747]	1	hSpCas9	negative selection	728801
4533314	4533337	17	+	26472758	K562	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.17434029193030653	[231]	[220]	1	hSpCas9	negative selection	728802
4533343	4533366	17	-	26472758	K562	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.5961986485229056	[350]	[195]	-4	hSpCas9	negative selection	728803
4533377	4533400	17	-	26472758	K562	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.48765419093120177	[696]	[824]	4	hSpCas9	negative selection	728804
4536381	4536404	17	-	26472758	K562	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.5304064103257785	[295]	[172]	-3	hSpCas9	negative selection	728805
4499280	4499303	17	-	26627737	DLD1	viability	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	2.2024653735865862	[91]	[87,235,84]	9	hSpCas9	negative selection	798289
4513243	4513266	17	-	26627737	DLD1	viability	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.452321825104404	[176]	[32,113,80]	4	hSpCas9	negative selection	798304
4525109	4525132	17	-	26627737	DLD1	viability	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.804722661486287	[317]	[207,193,126]	7	hSpCas9	negative selection	798306
4530757	4530780	17	+	26627737	DLD1	viability	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.6109132578097354	[337]	[146,235,111]	6	hSpCas9	negative selection	798307
4531076	4531099	17	-	26627737	DLD1	viability	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.1472779803287294	[939]	[379,228,195]	-1	hSpCas9	negative selection	798308
4532631	4532654	17	-	26627737	DLD1	viability	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.191572613818753	[222]	[55,40,81]	-2	hSpCas9	negative selection	798309
4499280	4499303	17	-	26627737	GBM cells	viability after 5 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	0.2925777233719621	[101]	[79,53]	4	hSpCas9	negative selection	880604
4513243	4513266	17	-	26627737	GBM cells	viability after 5 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.3002764372674527	[105]	[77,61]	4	hSpCas9	negative selection	880619
4525109	4525132	17	-	26627737	GBM cells	viability after 5 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.1831572580533477	[216]	[95,108]	-3	hSpCas9	negative selection	880621
4530757	4530780	17	+	26627737	GBM cells	viability after 5 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.08550990815527633	[238]	[122,148]	1	hSpCas9	negative selection	880622
4531076	4531099	17	-	26627737	GBM cells	viability after 5 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.04791546609297678	[292]	[137,165]	0	hSpCas9	negative selection	880623
4532631	4532654	17	-	26627737	GBM cells	viability after 5 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.40792752237354324	[129]	[126,57]	6	hSpCas9	negative selection	880624
4499280	4499303	17	-	26627737	GBM cells	viability after 13 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-0.006842452994019199	[101]	[80,33]	0	hSpCas9	negative selection	962919
4513243	4513266	17	-	26627737	GBM cells	viability after 13 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.2953882296996987	[105]	[58,79]	4	hSpCas9	negative selection	962934
4525109	4525132	17	-	26627737	GBM cells	viability after 13 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.7135066213422172	[216]	[89,56]	-7	hSpCas9	negative selection	962936
4530757	4530780	17	+	26627737	GBM cells	viability after 13 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.2946511372768412	[238]	[97,111]	-4	hSpCas9	negative selection	962937
4531076	4531099	17	-	26627737	GBM cells	viability after 13 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.25909891265974516	[292]	[208,174]	3	hSpCas9	negative selection	962938
4532631	4532654	17	-	26627737	GBM cells	viability after 13 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.9216226660734392	[129]	[110,151]	9	hSpCas9	negative selection	962939
4499280	4499303	17	-	26627737	GBM cells	viability after 21 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-1.1185099973075883	[101]	[24,25]	-7	hSpCas9	negative selection	1045234
4513243	4513266	17	-	26627737	GBM cells	viability after 21 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.5735361442775968	[105]	[80,89]	6	hSpCas9	negative selection	1045249
4525109	4525132	17	-	26627737	GBM cells	viability after 21 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.24453221630589805	[216]	[110,88]	-2	hSpCas9	negative selection	1045251
4530757	4530780	17	+	26627737	GBM cells	viability after 21 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.48561739943136945	[238]	[98,86]	-4	hSpCas9	negative selection	1045252
4531076	4531099	17	-	26627737	GBM cells	viability after 21 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.05432238147572363	[292]	[181,149]	0	hSpCas9	negative selection	1045253
4532631	4532654	17	-	26627737	GBM cells	viability after 21 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.6236948709662953	[129]	[112,104]	6	hSpCas9	negative selection	1045254
4499280	4499303	17	-	26627737	RPE1	viability after 9 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.829480158987241	[133]	[73,245]	8	hSpCas9	negative selection	1127549
4513243	4513266	17	-	26627737	RPE1	viability after 9 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-1.5372900052050085	[394]	[32,54]	-8	hSpCas9	negative selection	1127564
4525109	4525132	17	-	26627737	RPE1	viability after 9 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-1.5194901951523896	[984]	[138,66]	-8	hSpCas9	negative selection	1127566
4530757	4530780	17	+	26627737	RPE1	viability after 9 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.193786615856154	[639]	[188,280]	1	hSpCas9	negative selection	1127567
4531076	4531099	17	-	26627737	RPE1	viability after 9 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.0018097705940652853	[1504]	[414,544]	0	hSpCas9	negative selection	1127568
4532631	4532654	17	-	26627737	RPE1	viability after 9 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.7188977467669799	[621]	[85,159]	-5	hSpCas9	negative selection	1127569
4499280	4499303	17	-	26627737	RPE1	viability after 12 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.9373514044861504	[133]	[133,141]	8	hSpCas9	negative selection	1209864
4513243	4513266	17	-	26627737	RPE1	viability after 12 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.8659421121704801	[394]	[82,31]	-5	hSpCas9	negative selection	1209879
4525109	4525132	17	-	26627737	RPE1	viability after 12 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-2.0621078694538575	[984]	[75,49]	-8	hSpCas9	negative selection	1209881
4530757	4530780	17	+	26627737	RPE1	viability after 12 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.17843163830152337	[639]	[183,117]	-1	hSpCas9	negative selection	1209882
4531076	4531099	17	-	26627737	RPE1	viability after 12 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.21341650184550232	[1504]	[322,375]	-1	hSpCas9	negative selection	1209883
4532631	4532654	17	-	26627737	RPE1	viability after 12 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-1.1937059301607822	[621]	[57,88]	-7	hSpCas9	negative selection	1209884
4499280	4499303	17	-	26627737	RPE1	viability after 15 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.734363672702346	[133]	[90,159]	8	hSpCas9	negative selection	1292179
4513243	4513266	17	-	26627737	RPE1	viability after 15 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-1.633219194451231	[394]	[62,9]	-7	hSpCas9	negative selection	1292194
4525109	4525132	17	-	26627737	RPE1	viability after 15 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.9478927745268739	[984]	[203,86]	-5	hSpCas9	negative selection	1292196
4530757	4530780	17	+	26627737	RPE1	viability after 15 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.08509709720899228	[639]	[160,179]	0	hSpCas9	negative selection	1292197
4531076	4531099	17	-	26627737	RPE1	viability after 15 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.03508148264342892	[1504]	[339,528]	0	hSpCas9	negative selection	1292198
4532631	4532654	17	-	26627737	RPE1	viability after 15 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.4993346024429814	[621]	[125,122]	-3	hSpCas9	negative selection	1292199
4499280	4499303	17	-	26627737	RPE1	viability after 18 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	2.319415156191809	[133]	[194,164]	9	hSpCas9	negative selection	1374494
4513243	4513266	17	-	26627737	RPE1	viability after 18 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.9205282850451318	[394]	[50,61]	-5	hSpCas9	negative selection	1374509
4525109	4525132	17	-	26627737	RPE1	viability after 18 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.5461413806834439	[984]	[299,55]	-3	hSpCas9	negative selection	1374511
4530757	4530780	17	+	26627737	RPE1	viability after 18 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.11079031622952334	[639]	[69,310]	0	hSpCas9	negative selection	1374512
4531076	4531099	17	-	26627737	RPE1	viability after 18 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.25859530230640726	[1504]	[467,504]	1	hSpCas9	negative selection	1374513
4532631	4532654	17	-	26627737	RPE1	viability after 18 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-1.8333167099348744	[621]	[20,74]	-8	hSpCas9	negative selection	1374514
4499280	4499303	17	-	26627737	HeLa	viability after 8 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.2925897545364986	[128]	[215,108,106]	8	hSpCas9	negative selection	1456809
4513243	4513266	17	-	26627737	HeLa	viability after 8 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	3.543653325866536	[20]	[182,83,71]	9	hSpCas9	negative selection	1456824
4525109	4525132	17	-	26627737	HeLa	viability after 8 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.197425821703605	[311]	[175,104,88]	-2	hSpCas9	negative selection	1456826
4530757	4530780	17	+	26627737	HeLa	viability after 8 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.24732158639776908	[286]	[17,151,124]	-2	hSpCas9	negative selection	1456827
4531076	4531099	17	-	26627737	HeLa	viability after 8 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.5515367621420776	[1079]	[253,442,254]	-5	hSpCas9	negative selection	1456828
4532631	4532654	17	-	26627737	HeLa	viability after 8 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.9955228089540966	[190]	[118,248,121]	7	hSpCas9	negative selection	1456829
4499280	4499303	17	-	26627737	HeLa	viability after 12 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.5380219326903326	[128]	[109,174,175]	8	hSpCas9	negative selection	1539124
4513243	4513266	17	-	26627737	HeLa	viability after 12 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	3.52376014553124	[20]	[191,34,81]	9	hSpCas9	negative selection	1539139
4525109	4525132	17	-	26627737	HeLa	viability after 12 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.4744338810464904	[311]	[72,128,71]	-4	hSpCas9	negative selection	1539141
4530757	4530780	17	+	26627737	HeLa	viability after 12 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.1898598247431444	[286]	[212,60,141]	1	hSpCas9	negative selection	1539142
4531076	4531099	17	-	26627737	HeLa	viability after 12 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.7094121568871999	[1079]	[461,200,168]	-6	hSpCas9	negative selection	1539143
4532631	4532654	17	-	26627737	HeLa	viability after 12 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.8870017077822514	[190]	[178,125,135]	7	hSpCas9	negative selection	1539144
4499280	4499303	17	-	26627737	HeLa	viability after 15 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	0.5224289211540996	[128]	[23,114,88]	4	hSpCas9	negative selection	1621439
4513243	4513266	17	-	26627737	HeLa	viability after 15 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	3.7068140047988645	[20]	[116,91,126]	9	hSpCas9	negative selection	1621454
4525109	4525132	17	-	26627737	HeLa	viability after 15 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-2.1320169267400773	[311]	[16,17,53]	-9	hSpCas9	negative selection	1621456
4530757	4530780	17	+	26627737	HeLa	viability after 15 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.10828890008608943	[286]	[110,68,203]	0	hSpCas9	negative selection	1621457
4531076	4531099	17	-	26627737	HeLa	viability after 15 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.32174766458953696	[1079]	[412,223,422]	-3	hSpCas9	negative selection	1621458
4532631	4532654	17	-	26627737	HeLa	viability after 15 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.9992061196744927	[190]	[152,209,98]	7	hSpCas9	negative selection	1621459
4499280	4499303	17	-	26627737	HeLa	viability after 18 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	0.5794783271657775	[128]	[18,98,88]	5	hSpCas9	negative selection	1703754
4513243	4513266	17	-	26627737	HeLa	viability after 18 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	3.718421553011444	[20]	[77,78,126]	9	hSpCas9	negative selection	1703769
4525109	4525132	17	-	26627737	HeLa	viability after 18 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-2.0219159649224334	[311]	[14,15,53]	-9	hSpCas9	negative selection	1703771
4530757	4530780	17	+	26627737	HeLa	viability after 18 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.14673078591036698	[286]	[77,60,203]	1	hSpCas9	negative selection	1703772
4531076	4531099	17	-	26627737	HeLa	viability after 18 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.3018388941944605	[1079]	[282,189,422]	-3	hSpCas9	negative selection	1703773
4532631	4532654	17	-	26627737	HeLa	viability after 18 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	1.0249047568061225	[190]	[107,173,98]	7	hSpCas9	negative selection	1703774
4499280	4499303	17	-	26627737	HCT116	viability after 6 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	3.4073736631783706	[130]	[242,204]	9	hSpCas9	negative selection	1786069
4513243	4513266	17	-	26627737	HCT116	viability after 6 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	1.1538093764663584	[235]	[117,62]	6	hSpCas9	negative selection	1786084
4525109	4525132	17	-	26627737	HCT116	viability after 6 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-2.2767735474185193	[638]	[41,8]	-8	hSpCas9	negative selection	1786086
4530757	4530780	17	+	26627737	HCT116	viability after 6 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.6154899400441078	[644]	[48,213]	3	hSpCas9	negative selection	1786087
4531076	4531099	17	-	26627737	HCT116	viability after 6 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.7427444154776257	[775]	[178,217]	4	hSpCas9	negative selection	1786088
4532631	4532654	17	-	26627737	HCT116	viability after 6 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.3277674395095885	[493]	[217,30]	1	hSpCas9	negative selection	1786089
4499280	4499303	17	-	26627737	HCT116	viability after 8 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.32374541750014	[62]	[100,77,81]	9	hSpCas9	negative selection	1868384
4513243	4513266	17	-	26627737	HCT116	viability after 8 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.22117510671350304	[194]	[100,108,66]	-3	hSpCas9	negative selection	1868399
4525109	4525132	17	-	26627737	HCT116	viability after 8 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.09259382542760586	[204]	[148,97,71]	-1	hSpCas9	negative selection	1868401
4530757	4530780	17	+	26627737	HCT116	viability after 8 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.2588674639791817	[203]	[179,145,78]	3	hSpCas9	negative selection	1868402
4531076	4531099	17	-	26627737	HCT116	viability after 8 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.2734174407699649	[609]	[322,308,203]	-3	hSpCas9	negative selection	1868403
4532631	4532654	17	-	26627737	HCT116	viability after 8 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.0492008626370829	[204]	[105,90,152]	0	hSpCas9	negative selection	1868404
4499280	4499303	17	-	26627737	HCT116	viability after 9 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.463687091395053	[130]	[172,35]	8	hSpCas9	negative selection	1950699
4513243	4513266	17	-	26627737	HCT116	viability after 9 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	1.17410613636508	[235]	[125,154]	7	hSpCas9	negative selection	1950714
4525109	4525132	17	-	26627737	HCT116	viability after 9 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-3.4583911897186836	[638]	[0,26]	-9	hSpCas9	negative selection	1950716
4530757	4530780	17	+	26627737	HCT116	viability after 9 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.577260721943956	[644]	[158,80]	-4	hSpCas9	negative selection	1950717
4531076	4531099	17	-	26627737	HCT116	viability after 9 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.25191739990837086	[775]	[377,142]	2	hSpCas9	negative selection	1950718
4532631	4532654	17	-	26627737	HCT116	viability after 9 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.2774604523688738	[493]	[119,99]	-2	hSpCas9	negative selection	1950719
4499280	4499303	17	-	26627737	HCT116	viability after 12 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.6378628527732957	[62]	[143,40,118]	9	hSpCas9	negative selection	2033014
4513243	4513266	17	-	26627737	HCT116	viability after 12 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.32909218740605906	[194]	[129,61,47]	-3	hSpCas9	negative selection	2033029
4525109	4525132	17	-	26627737	HCT116	viability after 12 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.08796364448029331	[204]	[76,80,187]	0	hSpCas9	negative selection	2033031
4530757	4530780	17	+	26627737	HCT116	viability after 12 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.6119033466135547	[203]	[125,169,198]	6	hSpCas9	negative selection	2033032
4531076	4531099	17	-	26627737	HCT116	viability after 12 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.30467067757547606	[609]	[188,307,288]	-3	hSpCas9	negative selection	2033033
4532631	4532654	17	-	26627737	HCT116	viability after 12 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.2745702751939204	[204]	[81,96,88]	-3	hSpCas9	negative selection	2033034
4499280	4499303	17	-	26627737	HCT116	viability after 15 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.7211877881159277	[62]	[107,87,159]	9	hSpCas9	negative selection	2115329
4513243	4513266	17	-	26627737	HCT116	viability after 15 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.584012239867836	[194]	[277,152,86]	5	hSpCas9	negative selection	2115344
4525109	4525132	17	-	26627737	HCT116	viability after 15 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.16156677910565592	[204]	[109,116,164]	1	hSpCas9	negative selection	2115346
4530757	4530780	17	+	26627737	HCT116	viability after 15 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.5959688172752546	[203]	[174,96,257]	5	hSpCas9	negative selection	2115347
4531076	4531099	17	-	26627737	HCT116	viability after 15 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.06441134119403258	[609]	[405,213,392]	0	hSpCas9	negative selection	2115348
4532631	4532654	17	-	26627737	HCT116	viability after 15 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.36139522237663846	[204]	[153,76,51]	-4	hSpCas9	negative selection	2115349
4499280	4499303	17	-	26627737	HCT116	viability after 18 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	1.6056639909937178	[62]	[99,38,144]	9	hSpCas9	negative selection	2197644
4513243	4513266	17	-	26627737	HCT116	viability after 18 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.7736340211084576	[194]	[275,143,59]	6	hSpCas9	negative selection	2197659
4525109	4525132	17	-	26627737	HCT116	viability after 18 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.32133630593378926	[204]	[96,45,97]	-3	hSpCas9	negative selection	2197661
4530757	4530780	17	+	26627737	HCT116	viability after 18 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.643737959731367	[203]	[97,127,241]	5	hSpCas9	negative selection	2197662
4531076	4531099	17	-	26627737	HCT116	viability after 18 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.07482906309172832	[609]	[251,222,372]	0	hSpCas9	negative selection	2197663
4532631	4532654	17	-	26627737	HCT116	viability after 18 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.3400657095860564	[204]	[146,31,57]	-3	hSpCas9	negative selection	2197664
4524638	4524661	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACGGCACTCCAGCCTGG	SPNS2	ENSG00000183018	-0.056849389797668376	[44,102]	[10,20]	0	dCas9-VP64	positive selection	2473092
4524638	4524661	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACGGCACTCCAGCCTGG	SPNS2	ENSG00000183018	-0.4857295796910447	[163,101]	[25,34]	-5	dCas9-VP64	positive selection	2568347
4499393	4499416	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.4369192145278792	[2,1]	[1,0]	-6	hSpCas9	positive selection	3023440
4499358	4499381	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.5542473074156092	[2,2]	[1,0]	-7	hSpCas9	positive selection	3023441
4499393	4499416	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.568405547094761	[2,2]	[1,0]	-7	hSpCas9	positive selection	3091298
4499358	4499381	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-1.1344811514539819	[2,2]	[0,0]	-9	hSpCas9	positive selection	3091299
4531098	4531121		+	24336571	A375	resistance to PLX after 7 days	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	-0.4643989262798827	[14,13]	[9,10]	-9	hSpCas9	positive selection	3147188
4513236	4513259		+	24336571	A375	resistance to PLX after 7 days	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.13508774880678298	[18,20]	[24,18]	4	hSpCas9	positive selection	3147189
4513291	4513314		+	24336571	A375	resistance to PLX after 7 days	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	-0.2517227075700601	[6,5]	[4,4]	-7	hSpCas9	positive selection	3147190
4531098	4531121		+	24336571	A375	resistance to PLX after 14 days	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	-0.866484126121333	[11,13]	[1,3]	-8	hSpCas9	positive selection	3204981
4513236	4513259		+	24336571	A375	resistance to PLX after 14 days	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	1.6910513704677925	[17,14]	[25,24]	9	hSpCas9	positive selection	3204982
4513291	4513314		+	24336571	A375	resistance to PLX after 14 days	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	0.17043197834002122	[8,3]	[3,2]	1	hSpCas9	positive selection	3204983
4531098	4531121		+	24336571	A375	viability after 7 days	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	-0.1391196218549569	[16]	[14,13]	-2	hSpCas9	negative selection	3262774
4513236	4513259		+	24336571	A375	viability after 7 days	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	1.0469521562691333	[9]	[18,20]	9	hSpCas9	negative selection	3262775
4513291	4513314		+	24336571	A375	viability after 7 days	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	0.21963202883033373	[5]	[6,5]	3	hSpCas9	negative selection	3262776
4531098	4531121		+	24336571	A375	viability after 14 days	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	-0.26489027129378545	[16]	[11,13]	-3	hSpCas9	negative selection	3320567
4513236	4513259		+	24336571	A375	viability after 14 days	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.7850879844796768	[9]	[17,14]	8	hSpCas9	negative selection	3320568
4513291	4513314		+	24336571	A375	viability after 14 days	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	0.32494985089717543	[5]	[8,3]	4	hSpCas9	negative selection	3320569
4513236	4513259	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	-0.550028710611769	[223,223]	[0,0]	-4	hSpCas9	positive selection	3394737
4531056	4531079	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.7084580732162519	[249,249]	[0,0]	-5	hSpCas9	positive selection	3394738
4531051	4531074	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.10757909194115295	[141,141]	[0,0]	0	hSpCas9	positive selection	3394739
4499392	4499415	17	+	26780180	HT29	viability (Avana library 4 designs)	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	2.49572107742869	[]	[]	8	hSpCas9	negative selection	3462064
4499358	4499381	17	-	26780180	HT29	viability (Avana library 4 designs)	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.54632254095063	[]	[]	6	hSpCas9	negative selection	3462065
4499305	4499328	17	-	26780180	HT29	viability (Avana library 4 designs)	GTTTGGGCTGCTGAGCGCCGGGG	SPNS2	ENSG00000183018	0.0900404499115827	[]	[]	0	hSpCas9	negative selection	3462066
4530753	4530776	17	-	26780180	HT29	viability (Avana library 4 designs)	TGGGATGGCGAAGTAGAAGACGG	SPNS2	ENSG00000183018	1.24409577317042	[]	[]	5	hSpCas9	negative selection	3462067
4530753	4530776	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGGATGGCGAAGTAGAAGACGG	SPNS2	ENSG00000183018	0.0865066783935439	[]	[]	0	hSpCas9	negative selection	3563416
4499305	4499328	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGGGCTGCTGAGCGCCGGGG	SPNS2	ENSG00000183018	3.67128882481873	[]	[]	6	hSpCas9	negative selection	3563417
4499392	4499415	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	3.32734912160568	[]	[]	5	hSpCas9	negative selection	3563418
4499358	4499381	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.16444788721096	[]	[]	1	hSpCas9	negative selection	3563419
4530753	4530776	17	-	26780180	A375	viability (Avana lentiGuide)	TGGGATGGCGAAGTAGAAGACGG	SPNS2	ENSG00000183018	5.8812395887337	[]	[]	5	hSpCas9	negative selection	3672075
4499305	4499328	17	-	26780180	A375	viability (Avana lentiGuide)	GTTTGGGCTGCTGAGCGCCGGGG	SPNS2	ENSG00000183018	0.220636609237495	[]	[]	0	hSpCas9	negative selection	3672076
4499392	4499415	17	+	26780180	A375	viability (Avana lentiGuide)	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.207657835493874	[]	[]	0	hSpCas9	negative selection	3672077
4499358	4499381	17	-	26780180	A375	viability (Avana lentiGuide)	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.29748541313233	[]	[]	0	hSpCas9	negative selection	3672078
4530753	4530776	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGGATGGCGAAGTAGAAGACGG	SPNS2	ENSG00000183018	-0.07690820315016031	[5]	[5,3]	-1	hSpCas9	positive selection	3780682
4499305	4499328	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGGGCTGCTGAGCGCCGGGG	SPNS2	ENSG00000183018	0.10945128059104882	[4]	[4,4]	3	hSpCas9	positive selection	3780683
4499392	4499415	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.5840078742696727	[4]	[3,1]	-7	hSpCas9	positive selection	3780684
4499358	4499381	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.21202714105792697	[3]	[3,4]	6	hSpCas9	positive selection	3780685
4530753	4530776	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGGATGGCGAAGTAGAAGACGG	SPNS2	ENSG00000183018	-0.2125609198410735	[5]	[2,4]	-3	hSpCas9	positive selection	3889289
4499305	4499328	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGGGCTGCTGAGCGCCGGGG	SPNS2	ENSG00000183018	-0.2885834180431619	[5]	[2,4]	-4	hSpCas9	positive selection	3889290
4499392	4499415	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.7614937554460715	[3]	[0,1]	-7	hSpCas9	positive selection	3889291
4499358	4499381	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.17016069055636288	[4]	[3,4]	4	hSpCas9	positive selection	3889292
4531051	4531074	17	+	26780180	A375	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	1.76835435924024	[]	[]	9	hSpCas9	negative selection	3999037
4536922	4536945	17	+	26780180	A375	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	1.02186967789012	[]	[]	5	hSpCas9	negative selection	3999038
4513236	4513259	17	+	26780180	A375	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.75819027906871	[]	[]	3	hSpCas9	negative selection	3999039
4525086	4525109	17	-	26780180	A375	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	1.13843192714004	[]	[]	6	hSpCas9	negative selection	3999040
4525082	4525105	17	+	26780180	A375	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.821991668084828	[]	[]	3	hSpCas9	negative selection	3999041
4531056	4531079	17	-	26780180	A375	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	2.13139287751112	[]	[]	9	hSpCas9	negative selection	3999042
4531051	4531074	17	+	26780180	HT29	viability (GeCKOv2 library)	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	1.80997239578875	[]	[]	8	hSpCas9	negative selection	4107003
4536922	4536945	17	+	26780180	HT29	viability (GeCKOv2 library)	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.0923180375018495	[]	[]	0	hSpCas9	negative selection	4107004
4513236	4513259	17	+	26780180	HT29	viability (GeCKOv2 library)	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	1.09054940488048	[]	[]	5	hSpCas9	negative selection	4107005
4525086	4525109	17	-	26780180	HT29	viability (GeCKOv2 library)	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.691186356494012	[]	[]	2	hSpCas9	negative selection	4107006
4525082	4525105	17	+	26780180	HT29	viability (GeCKOv2 library)	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.629048939581636	[]	[]	2	hSpCas9	negative selection	4107007
4531056	4531079	17	-	26780180	HT29	viability (GeCKOv2 library)	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	1.96277785368185	[]	[]	9	hSpCas9	negative selection	4107008
4531098	4531121	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	-0.5134334746875595	[3]	[1,1]	-8	hSpCas9	positive selection	4173363
4513236	4513259	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.3622336122813136	[4]	[2,4]	8	hSpCas9	positive selection	4173364
4513291	4513314	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	-0.3135082990437965	[3]	[1,1]	-6	hSpCas9	positive selection	4173365
4531098	4531121	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACTGGCACTGGGCATTGCGGG	SPNS2	ENSG00000183018	0.7965858260653658	[3]	[4,0,0,3]	5	hSpCas9	positive selection	4237385
4513236	4513259	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.061075877591598035	[3]	[3,0,1,0]	0	hSpCas9	positive selection	4237386
4513291	4513314	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGCCGGCCTGCTGCAGTCAGG	SPNS2	ENSG00000183018	1.0373819815844154	[3]	[1,2,0,3]	7	hSpCas9	positive selection	4237387
4525086	4525109	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.1362526141448246	[3]	[2,2]	2	hSpCas9	positive selection	4300360
4525082	4525105	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.3887986143421229	[3]	[3,3]	7	hSpCas9	positive selection	4300361
4536922	4536945	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.057708506873624284	[3]	[3,1]	-1	hSpCas9	positive selection	4300362
4513236	4513259	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.396791866723927	[3]	[3,3]	7	hSpCas9	positive selection	4364615
4531056	4531079	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.5396164668916335	[3]	[1,0]	-8	hSpCas9	positive selection	4364616
4531051	4531074	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.48483118816842663	[2]	[1,0]	-8	hSpCas9	positive selection	4364617
4499221	4499243	17	+	27760321	OCIAML3	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.21788403703899947	[453,388]	[330,448]	2	hSpCas9	negative selection	4442826
4499393	4499415	17	+	27760321	OCIAML3	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.14806831881004007	[328,267]	[295,206]	1	hSpCas9	negative selection	4442827
4525104	4525126	17	+	27760321	OCIAML3	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.6373267208576947	[508,453]	[422,795]	7	hSpCas9	negative selection	4442828
4530699	4530721	17	-	27760321	OCIAML3	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.2395007074877368	[543,454]	[398,537]	3	hSpCas9	negative selection	4442829
4530718	4530740	17	-	27760321	OCIAML3	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.11076414191055384	[458,416]	[336,290]	-1	hSpCas9	negative selection	4442830
4499221	4499243	17	+	27760321	OCIAML2	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.18288875040122374	[453,388]	[381,390]	2	hSpCas9	negative selection	4526289
4499393	4499415	17	+	27760321	OCIAML2	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.058079705857214114	[328,267]	[212,298]	0	hSpCas9	negative selection	4526290
4525104	4525126	17	+	27760321	OCIAML2	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.686260139073179	[508,453]	[495,796]	8	hSpCas9	negative selection	4526291
4530699	4530721	17	-	27760321	OCIAML2	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	-0.36340820527920437	[543,454]	[336,280]	-4	hSpCas9	negative selection	4526292
4530718	4530740	17	-	27760321	OCIAML2	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.0175336204792255	[458,416]	[313,396]	0	hSpCas9	negative selection	4526293
4499221	4499243	17	+	27760321	MV411	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.18635676007095342	[453,388]	[239,428]	1	hSpCas9	negative selection	4609752
4499393	4499415	17	+	27760321	MV411	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.8257478259422625	[328,267]	[70,169]	-5	hSpCas9	negative selection	4609753
4525104	4525126	17	+	27760321	MV411	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	1.2856409544466876	[508,453]	[938,524]	8	hSpCas9	negative selection	4609754
4530699	4530721	17	-	27760321	MV411	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.4842315921290459	[543,454]	[493,406]	3	hSpCas9	negative selection	4609755
4530718	4530740	17	-	27760321	MV411	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.026528558877942143	[458,416]	[265,309]	0	hSpCas9	negative selection	4609756
4499221	4499243	17	+	27760321	HL60	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	-0.03395615404479207	[453,388]	[327,342]	0	hSpCas9	negative selection	4693215
4499393	4499415	17	+	27760321	HL60	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.3648611917359255	[328,267]	[275,350]	4	hSpCas9	negative selection	4693216
4525104	4525126	17	+	27760321	HL60	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.8370570582133676	[508,453]	[772,625]	8	hSpCas9	negative selection	4693217
4530699	4530721	17	-	27760321	HL60	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.08675348479384656	[543,454]	[433,428]	1	hSpCas9	negative selection	4693218
4530718	4530740	17	-	27760321	HL60	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.48078902332513157	[458,416]	[246,265]	-5	hSpCas9	negative selection	4693219
4499221	4499243	17	+	27760321	HT1080	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	-0.8577811297209876	[388,303]	[121,25]	-4	hSpCas9	negative selection	4776678
4499393	4499415	17	+	27760321	HT1080	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.7089470323849896	[267,208]	[7,112]	-3	hSpCas9	negative selection	4776679
4525104	4525126	17	+	27760321	HT1080	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	1.2182490262823427	[453,353]	[372,375]	6	hSpCas9	negative selection	4776680
4530699	4530721	17	-	27760321	HT1080	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	1.5644391291731004	[454,354]	[248,726]	8	hSpCas9	negative selection	4776681
4530718	4530740	17	-	27760321	HT1080	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-2.4293801612828076	[416,325]	[26,27]	-7	hSpCas9	negative selection	4776682
4499221	4499243	17	+	27760321	HT29	viability after 7 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.1161864821798029	[388,303]	[631,504,336]	1	hSpCas9	negative selection	4860141
4499393	4499415	17	+	27760321	HT29	viability after 7 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.008942769395003602	[267,208]	[345,184,385]	0	hSpCas9	negative selection	4860142
4525104	4525126	17	+	27760321	HT29	viability after 7 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.274961408616043	[453,353]	[790,690,431]	4	hSpCas9	negative selection	4860143
4530699	4530721	17	-	27760321	HT29	viability after 7 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.16540786807169813	[454,354]	[647,522,588]	2	hSpCas9	negative selection	4860144
4530718	4530740	17	-	27760321	HT29	viability after 7 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.2874863184744904	[416,325]	[704,393,663]	4	hSpCas9	negative selection	4860145
4499221	4499243	17	+	27760321	HT29	viability after 25 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.42733040581250664	[388,303]	[453,440,726]	4	hSpCas9	negative selection	4943604
4499393	4499415	17	+	27760321	HT29	viability after 25 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.04555326925958769	[267,208]	[339,260,176]	0	hSpCas9	negative selection	4943605
4525104	4525126	17	+	27760321	HT29	viability after 25 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.3144087913664326	[453,353]	[593,449,687]	3	hSpCas9	negative selection	4943606
4530699	4530721	17	-	27760321	HT29	viability after 25 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.4559115575494527	[454,354]	[560,722,622]	5	hSpCas9	negative selection	4943607
4530718	4530740	17	-	27760321	HT29	viability after 25 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.3275500060662071	[416,325]	[596,451,545]	3	hSpCas9	negative selection	4943608
4499221	4499243	17	+	27760321	HT29	viability after 22 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	-0.09130284445710093	[388,303]	[267,383,479]	-1	hSpCas9	negative selection	5027067
4499393	4499415	17	+	27760321	HT29	viability after 22 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.3562843133814414	[267,208]	[479,259,314]	4	hSpCas9	negative selection	5027068
4525104	4525126	17	+	27760321	HT29	viability after 22 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.45629605040363896	[453,353]	[744,472,701]	5	hSpCas9	negative selection	5027069
4530699	4530721	17	-	27760321	HT29	viability after 22 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.21685094458493617	[454,354]	[488,480,664]	2	hSpCas9	negative selection	5027070
4530718	4530740	17	-	27760321	HT29	viability after 22 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.2873877006739845	[416,325]	[538,525,506]	3	hSpCas9	negative selection	5027071
4499221	4499243	17	+	27760321	HT29	viability after 19 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.5704961155987398	[388,303]	[500,235,1002]	6	hSpCas9	negative selection	5110530
4499393	4499415	17	+	27760321	HT29	viability after 19 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.30676327787083135	[267,208]	[336,73,260]	-3	hSpCas9	negative selection	5110531
4525104	4525126	17	+	27760321	HT29	viability after 19 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.6180770484155086	[453,353]	[637,733,745]	6	hSpCas9	negative selection	5110532
4530699	4530721	17	-	27760321	HT29	viability after 19 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.060660536991247516	[454,354]	[428,551,462]	0	hSpCas9	negative selection	5110533
4530718	4530740	17	-	27760321	HT29	viability after 19 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.41446148317621684	[416,325]	[531,246,203]	-4	hSpCas9	negative selection	5110534
4499221	4499243	17	+	27760321	HT29	viability after 16 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.2851844524178707	[388,303]	[354,400,651]	3	hSpCas9	negative selection	5193993
4499393	4499415	17	+	27760321	HT29	viability after 16 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.03240299185458184	[267,208]	[462,102,274]	0	hSpCas9	negative selection	5193994
4525104	4525126	17	+	27760321	HT29	viability after 16 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.110267846809843	[453,353]	[385,560,504]	1	hSpCas9	negative selection	5193995
4530699	4530721	17	-	27760321	HT29	viability after 16 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.1630669468455576	[454,354]	[400,386,726]	1	hSpCas9	negative selection	5193996
4530718	4530740	17	-	27760321	HT29	viability after 16 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.6472905690620087	[416,325]	[950,626,403]	7	hSpCas9	negative selection	5193997
4499221	4499243	17	+	27760321	HT29	viability after 13 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.0359244824550818	[388,303]	[299,564,373]	0	hSpCas9	negative selection	5277456
4499393	4499415	17	+	27760321	HT29	viability after 13 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.01756389271813108	[267,208]	[329,331,183]	0	hSpCas9	negative selection	5277457
4525104	4525126	17	+	27760321	HT29	viability after 13 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.6117892952285044	[453,353]	[826,755,573]	7	hSpCas9	negative selection	5277458
4530699	4530721	17	-	27760321	HT29	viability after 13 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	0.23936783605691322	[454,354]	[688,411,561]	3	hSpCas9	negative selection	5277459
4530718	4530740	17	-	27760321	HT29	viability after 13 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	-0.17233428764676084	[416,325]	[329,425,390]	-2	hSpCas9	negative selection	5277460
4499221	4499243	17	+	27760321	HT29	viability after 10 days	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.13519495758958683	[388,303]	[619,381,421]	1	hSpCas9	negative selection	5360919
4499393	4499415	17	+	27760321	HT29	viability after 10 days	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.15242522554158144	[267,208]	[277,418,298]	2	hSpCas9	negative selection	5360920
4525104	4525126	17	+	27760321	HT29	viability after 10 days	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	0.4393301149552371	[453,353]	[853,633,564]	6	hSpCas9	negative selection	5360921
4530699	4530721	17	-	27760321	HT29	viability after 10 days	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	-0.052106730504865306	[454,354]	[387,590,486]	0	hSpCas9	negative selection	5360922
4530718	4530740	17	-	27760321	HT29	viability after 10 days	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.23967542859620117	[416,325]	[779,341,515]	3	hSpCas9	negative selection	5360923
4499221	4499243	17	+	27760321	MOLM13	viability	GACGCTGTCGGGCAGCGTAAGG	SPNS2	ENSG00000183018	0.16067183526994447	[453,388]	[284,247]	1	hSpCas9	negative selection	5444382
4499393	4499415	17	+	27760321	MOLM13	viability	TACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.3626167169415085	[328,267]	[175,248]	2	hSpCas9	negative selection	5444383
4525104	4525126	17	+	27760321	MOLM13	viability	GGCGACCGCTTCAACAGGAAGG	SPNS2	ENSG00000183018	-0.13290654033651494	[508,453]	[167,314]	-1	hSpCas9	negative selection	5444384
4530699	4530721	17	-	27760321	MOLM13	viability	AGGTCGCCAATGATAGTGGGGG	SPNS2	ENSG00000183018	-0.5022690594089737	[543,454]	[269,136]	-3	hSpCas9	negative selection	5444385
4530718	4530740	17	-	27760321	MOLM13	viability	ACGCGTGTTCTTGGTGAAGAGG	SPNS2	ENSG00000183018	0.3739617092902244	[458,416]	[480,182]	2	hSpCas9	negative selection	5444386
4498939	4498962	17	+	27661255	K562	viability	GCCCGACCAGGATGGTGCAGTGG	SPNS2	ENSG00000183018	0.15370485275993312	[770,833]	[791,643]	5	dCas9-KRAB	negative selection	5514019
4499053	4499076	17	+	27661255	K562	viability	GTGCCTGGAATGCGCCTCGGCGG	SPNS2	ENSG00000183018	0.21956658039205146	[597,694]	[630,572]	7	dCas9-KRAB	negative selection	5514020
4499210	4499233	17	+	27661255	K562	viability	GATGAGGTGCAGACGCTGTCGGG	SPNS2	ENSG00000183018	-0.010902098852910047	[1090,1009]	[928,752]	0	dCas9-KRAB	negative selection	5514021
4499358	4499381	17	-	27661255	K562	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.3040770155722604	[577,591]	[607,549]	8	dCas9-KRAB	negative selection	5514022
4525086	4525109	17	-	27260156	BXPC3	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.2823269113907394	[580]	[570,589,880,965]	6	hSpCas9	negative selection	5572820
4525082	4525105	17	+	27260156	BXPC3	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.33433009731548424	[748]	[1005,919,991,1031]	7	hSpCas9	negative selection	5572821
4536922	4536945	17	+	27260156	BXPC3	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.2689660466798289	[545]	[696,594,596,884]	6	hSpCas9	negative selection	5572822
4513236	4513259	17	+	27260156	BXPC3	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.2537069195167003	[533]	[593,657,624,805]	5	hSpCas9	negative selection	5637075
4531056	4531079	17	-	27260156	BXPC3	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.029733807915355376	[527]	[540,531,462,633]	0	hSpCas9	negative selection	5637076
4531051	4531074	17	+	27260156	BXPC3	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.22644670853358334	[420]	[284,437,320,475]	-5	hSpCas9	negative selection	5637077
4525086	4525109	17	-	27260156	A673	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.0015625508199659244	[580]	[750,577,709,765]	0	hSpCas9	negative selection	5694071
4525082	4525105	17	+	27260156	A673	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4142891015756959	[748]	[1244,1215,1167,1165]	8	hSpCas9	negative selection	5694072
4536922	4536945	17	+	27260156	A673	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.17765507971025918	[545]	[722,679,808,751]	4	hSpCas9	negative selection	5694073
4513236	4513259	17	+	27260156	A673	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.1424283355554197	[533]	[842,676,555,774]	3	hSpCas9	negative selection	5758326
4531056	4531079	17	-	27260156	A673	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.2796758759691265	[527]	[482,506,445,655]	-6	hSpCas9	negative selection	5758327
4531051	4531074	17	+	27260156	A673	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.06980283187493852	[420]	[497,469,474,484]	-2	hSpCas9	negative selection	5758328
4525086	4525109	17	-	27260156	A375	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.14484749570569377	[580]	[535,668,771,496]	-2	hSpCas9	negative selection	5815322
4525082	4525105	17	+	27260156	A375	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.644997321971157	[748]	[1194,1775,1209,1343]	8	hSpCas9	negative selection	5815323
4536922	4536945	17	+	27260156	A375	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.0409095490804805	[545]	[579,747,632,542]	0	hSpCas9	negative selection	5815324
4513236	4513259	17	+	27260156	A375	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.4175336825508489	[533]	[909,754,906,755]	6	hSpCas9	negative selection	5879577
4531056	4531079	17	-	27260156	A375	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.26142094068873567	[527]	[361,619,632,460]	-4	hSpCas9	negative selection	5879578
4531051	4531074	17	+	27260156	A375	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.04927922053973097	[420]	[457,478,492,588]	0	hSpCas9	negative selection	5879579
4525086	4525109	17	-	27260156	COLO741	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.045976523342029174	[580]	[783,749,764]	1	hSpCas9	negative selection	5936573
4525082	4525105	17	+	27260156	COLO741	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.3689604578645168	[748]	[1288,1235,1187]	7	hSpCas9	negative selection	5936574
4536922	4536945	17	+	27260156	COLO741	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.09243982885836899	[545]	[833,879,538]	2	hSpCas9	negative selection	5936575
4513236	4513259	17	+	27260156	COLO741	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.20587096912039046	[533]	[900,575,883]	4	hSpCas9	negative selection	6000828
4531056	4531079	17	-	27260156	COLO741	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.11432999664008783	[527]	[902,758,554]	2	hSpCas9	negative selection	6000829
4531051	4531074	17	+	27260156	COLO741	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.05595259298194638	[420]	[642,615,317]	-1	hSpCas9	negative selection	6000830
4525086	4525109	17	-	27260156	CAL120	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.13968538802967162	[580]	[760,1004,620]	2	hSpCas9	negative selection	6057824
4525082	4525105	17	+	27260156	CAL120	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.6206085049120685	[748]	[1975,1349,1060]	8	hSpCas9	negative selection	6057825
4536922	4536945	17	+	27260156	CAL120	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.13383089650183394	[545]	[718,591,917]	2	hSpCas9	negative selection	6057826
4513236	4513259	17	+	27260156	CAL120	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.416623192883975	[533]	[1121,746,827]	6	hSpCas9	negative selection	6122079
4531056	4531079	17	-	27260156	CAL120	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.0029361100143290852	[527]	[760,751,472]	0	hSpCas9	negative selection	6122080
4531051	4531074	17	+	27260156	CAL120	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.2949449077193826	[420]	[677,344,297]	-4	hSpCas9	negative selection	6122081
4525086	4525109	17	-	27260156	CADOES1	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.28678801054164127	[580]	[581,933,579,536]	5	hSpCas9	negative selection	6179075
4525082	4525105	17	+	27260156	CADOES1	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.6286615628016544	[748]	[1055,1083,1072,1095]	8	hSpCas9	negative selection	6179076
4536922	4536945	17	+	27260156	CADOES1	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.17852790667886642	[545]	[550,658,617,466]	3	hSpCas9	negative selection	6179077
4513236	4513259	17	+	27260156	CADOES1	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.48833218700512404	[533]	[637,621,748,780]	7	hSpCas9	negative selection	6243330
4531056	4531079	17	-	27260156	CADOES1	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.20898272869264703	[527]	[329,384,521,463]	-4	hSpCas9	negative selection	6243331
4531051	4531074	17	+	27260156	CADOES1	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.10178037555195585	[420]	[324,435,302,396]	-2	hSpCas9	negative selection	6243332
4525086	4525109	17	-	27260156	EWS502	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.3549120572635591	[580]	[955,771,729,656]	6	hSpCas9	negative selection	6300326
4525082	4525105	17	+	27260156	EWS502	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4824877485421529	[748]	[825,1096,1092,1473]	8	hSpCas9	negative selection	6300327
4536922	4536945	17	+	27260156	EWS502	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.03048472145333625	[545]	[456,559,697,669]	0	hSpCas9	negative selection	6300328
4513236	4513259	17	+	27260156	EWS502	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.17279910955825076	[533]	[568,397,667,953]	3	hSpCas9	negative selection	6364581
4531056	4531079	17	-	27260156	EWS502	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.008464156924824412	[527]	[422,741,659,423]	0	hSpCas9	negative selection	6364582
4531051	4531074	17	+	27260156	EWS502	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.11437778967748641	[420]	[410,506,478,543]	2	hSpCas9	negative selection	6364583
4525086	4525109	17	-	27260156	EW8	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.19913621028235529	[580]	[672,436,400,686]	3	hSpCas9	negative selection	6421577
4525082	4525105	17	+	27260156	EW8	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.5342293941613819	[748]	[883,1052,545,1087]	8	hSpCas9	negative selection	6421578
4536922	4536945	17	+	27260156	EW8	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.005342758858656815	[545]	[404,499,425,429]	0	hSpCas9	negative selection	6421579
4513236	4513259	17	+	27260156	EW8	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.799195595797156	[533]	[820,615,954,590]	9	hSpCas9	negative selection	6485832
4531056	4531079	17	-	27260156	EW8	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.1513902377696042	[527]	[348,309,404,467]	-3	hSpCas9	negative selection	6485833
4531051	4531074	17	+	27260156	EW8	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.02959721625526196	[420]	[574,298,249,252]	0	hSpCas9	negative selection	6485834
4525086	4525109	17	-	27260156	CORL105	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.0604921339228327	[580]	[747,620,791,691]	1	hSpCas9	negative selection	6542828
4525082	4525105	17	+	27260156	CORL105	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.6252050760882034	[748]	[1249,1385,1827,1016]	9	hSpCas9	negative selection	6542829
4536922	4536945	17	+	27260156	CORL105	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.32026299763053634	[545]	[1075,548,825,759]	6	hSpCas9	negative selection	6542830
4513236	4513259	17	+	27260156	CORL105	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.16339158694490294	[533]	[736,706,671,680]	3	hSpCas9	negative selection	6607083
4531056	4531079	17	-	27260156	CORL105	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.173727132379103	[527]	[719,587,945,576]	3	hSpCas9	negative selection	6607084
4531051	4531074	17	+	27260156	CORL105	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.04203615304369926	[420]	[549,441,453,467]	-1	hSpCas9	negative selection	6607085
4525086	4525109	17	-	27260156	HS294T	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.2578347263964982	[580]	[157,201,176,221]	-4	hSpCas9	negative selection	6664079
4525082	4525105	17	+	27260156	HS294T	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.7082069214367218	[748]	[494,467,532,376]	8	hSpCas9	negative selection	6664080
4536922	4536945	17	+	27260156	HS294T	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.34700515115736597	[545]	[352,137,296,283]	4	hSpCas9	negative selection	6664081
4513236	4513259	17	+	27260156	HS294T	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.5001711306331181	[533]	[237,293,194,475]	6	hSpCas9	negative selection	6728334
4531056	4531079	17	-	27260156	HS294T	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.12836809963421122	[527]	[250,201,212,223]	1	hSpCas9	negative selection	6728335
4531051	4531074	17	+	27260156	HS294T	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.20554714175357403	[420]	[150,112,179,115]	-3	hSpCas9	negative selection	6728336
4525086	4525109	17	-	27260156	HCC44	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.09281120168745499	[580]	[447,872,942,532]	1	hSpCas9	negative selection	6785330
4525082	4525105	17	+	27260156	HCC44	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.712904956382881	[748]	[1194,1278,1999,1178]	9	hSpCas9	negative selection	6785331
4536922	4536945	17	+	27260156	HCC44	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.19319429347792494	[545]	[669,632,616,883]	3	hSpCas9	negative selection	6785332
4513236	4513259	17	+	27260156	HCC44	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.34142625647092395	[533]	[752,746,949,641]	5	hSpCas9	negative selection	6849585
4531056	4531079	17	-	27260156	HCC44	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.18139419808666696	[527]	[601,552,553,404]	-3	hSpCas9	negative selection	6849586
4531051	4531074	17	+	27260156	HCC44	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.055997841676533266	[420]	[667,492,276,375]	-1	hSpCas9	negative selection	6849587
4525086	4525109	17	-	27260156	G402	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.14665698291937507	[580]	[1043,628,907,592]	1	hSpCas9	negative selection	6906581
4525082	4525105	17	+	27260156	G402	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.8362769168834051	[748]	[1485,1866,1584,1577]	9	hSpCas9	negative selection	6906582
4536922	4536945	17	+	27260156	G402	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.49615892960843677	[545]	[1067,676,1044,966]	6	hSpCas9	negative selection	6906583
4513236	4513259	17	+	27260156	G402	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.48081388997229657	[533]	[1769,746,606,637]	6	hSpCas9	negative selection	6970836
4531056	4531079	17	-	27260156	G402	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.39665594813662963	[527]	[740,780,598,1229]	5	hSpCas9	negative selection	6970837
4531051	4531074	17	+	27260156	G402	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.08919933285583986	[420]	[497,343,458,848]	1	hSpCas9	negative selection	6970838
4525086	4525109	17	-	27260156	L33	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.1814580182199783	[580]	[605,288,437,628]	4	hSpCas9	negative selection	7027832
4525082	4525105	17	+	27260156	L33	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4463435615095973	[748]	[996,424,627,1048]	8	hSpCas9	negative selection	7027833
4536922	4536945	17	+	27260156	L33	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.3302823350172447	[545]	[757,295,319,752]	7	hSpCas9	negative selection	7027834
4513236	4513259	17	+	27260156	L33	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.2426881187095978	[533]	[653,252,413,596]	5	hSpCas9	negative selection	7092087
4531056	4531079	17	-	27260156	L33	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.0052977483809072135	[527]	[537,216,371,460]	0	hSpCas9	negative selection	7092088
4531051	4531074	17	+	27260156	L33	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.4740141877847793	[420]	[323,127,181,285]	-8	hSpCas9	negative selection	7092089
4525086	4525109	17	-	27260156	K562	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.3522854579907496	[580]	[422,716,590,858]	4	hSpCas9	negative selection	7149083
4525082	4525105	17	+	27260156	K562	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.15100629732053295	[748]	[605,663,970,697]	1	hSpCas9	negative selection	7149084
4536922	4536945	17	+	27260156	K562	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.0059647229633970344	[545]	[539,627,490,316]	0	hSpCas9	negative selection	7149085
4513236	4513259	17	+	27260156	K562	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.7198196782414494	[533]	[601,548,1246,702]	8	hSpCas9	negative selection	7213338
4531056	4531079	17	-	27260156	K562	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.42040583977161083	[527]	[315,509,373,219]	-5	hSpCas9	negative selection	7213339
4531051	4531074	17	+	27260156	K562	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.23528378050396453	[420]	[336,512,262,182]	-3	hSpCas9	negative selection	7213340
4525086	4525109	17	-	27260156	HT29	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.1832058859413161	[580]	[859,875,839,654]	3	hSpCas9	negative selection	7270334
4525082	4525105	17	+	27260156	HT29	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.3595204494467791	[748]	[1273,1310,1195,932]	7	hSpCas9	negative selection	7270335
4536922	4536945	17	+	27260156	HT29	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.02439523614718525	[545]	[774,654,710,572]	0	hSpCas9	negative selection	7270336
4513236	4513259	17	+	27260156	HT29	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.23862226212593682	[533]	[654,975,746,697]	4	hSpCas9	negative selection	7334589
4531056	4531079	17	-	27260156	HT29	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.21866187129912112	[527]	[669,690,549,338]	-4	hSpCas9	negative selection	7334590
4531051	4531074	17	+	27260156	HT29	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.21242064001887268	[420]	[435,454,419,451]	-4	hSpCas9	negative selection	7334591
4525086	4525109	17	-	27260156	MHHES1	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.1121965170641816	[580]	[706,1011,700,477]	2	hSpCas9	negative selection	7391585
4525082	4525105	17	+	27260156	MHHES1	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.585172604678755	[748]	[1427,1382,1115,1160]	8	hSpCas9	negative selection	7391586
4536922	4536945	17	+	27260156	MHHES1	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.350771627632541	[545]	[943,975,728,560]	6	hSpCas9	negative selection	7391587
4513236	4513259	17	+	27260156	MHHES1	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.4692361862818488	[533]	[872,662,802,934]	8	hSpCas9	negative selection	7455840
4531056	4531079	17	-	27260156	MHHES1	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.6828506620000939	[527]	[626,2124,653,560]	9	hSpCas9	negative selection	7455841
4531051	4531074	17	+	27260156	MHHES1	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.11708249116850958	[420]	[707,535,405,437]	2	hSpCas9	negative selection	7455842
4525086	4525109	17	-	27260156	MEWO	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.05030382947282752	[580]	[544,437,595]	-1	hSpCas9	negative selection	7512836
4525082	4525105	17	+	27260156	MEWO	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.36985540410465945	[748]	[1013,974,747]	7	hSpCas9	negative selection	7512837
4536922	4536945	17	+	27260156	MEWO	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.12388749331853732	[545]	[689,469,535]	2	hSpCas9	negative selection	7512838
4513236	4513259	17	+	27260156	MEWO	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.30727724321224115	[533]	[558,808,473]	6	hSpCas9	negative selection	7577091
4531056	4531079	17	-	27260156	MEWO	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.010202304596679507	[527]	[490,382,597]	0	hSpCas9	negative selection	7577092
4531051	4531074	17	+	27260156	MEWO	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.2538761593695644	[420]	[390,254,356]	-5	hSpCas9	negative selection	7577093
4525086	4525109	17	-	27260156	LNCAPCLONEFGC	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.3531419173572017	[580]	[535,665,660,826]	5	hSpCas9	negative selection	7634087
4525082	4525105	17	+	27260156	LNCAPCLONEFGC	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.5816467894786962	[748]	[1066,906,1095,1008]	8	hSpCas9	negative selection	7634088
4536922	4536945	17	+	27260156	LNCAPCLONEFGC	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.1727396033172247	[545]	[471,501,779,513]	2	hSpCas9	negative selection	7634089
4513236	4513259	17	+	27260156	LNCAPCLONEFGC	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.5542220726159054	[533]	[563,692,853,754]	8	hSpCas9	negative selection	7698342
4531056	4531079	17	-	27260156	LNCAPCLONEFGC	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.06225581658593926	[527]	[690,264,536,358]	-1	hSpCas9	negative selection	7698343
4531051	4531074	17	+	27260156	LNCAPCLONEFGC	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.08076907360743366	[420]	[339,338,481,300]	-1	hSpCas9	negative selection	7698344
4525086	4525109	17	-	27260156	PANC0327	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.005043750740382658	[580]	[454,671,543,360]	0	hSpCas9	negative selection	7755338
4525082	4525105	17	+	27260156	PANC0327	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.6507997784190035	[748]	[1006,1161,1058,931]	8	hSpCas9	negative selection	7755339
4536922	4536945	17	+	27260156	PANC0327	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.42202054274364964	[545]	[693,659,458,787]	6	hSpCas9	negative selection	7755340
4513236	4513259	17	+	27260156	PANC0327	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.06054415507321087	[533]	[522,618,501,320]	0	hSpCas9	negative selection	7819593
4531056	4531079	17	-	27260156	PANC0327	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.6168418422935792	[527]	[851,541,915,600]	8	hSpCas9	negative selection	7819594
4531051	4531074	17	+	27260156	PANC0327	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.20027843966637454	[420]	[752,229,476,310]	3	hSpCas9	negative selection	7819595
4525086	4525109	17	-	27260156	NCIH2009	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.5058015185216757	[580]	[1284,1154,1041]	7	hSpCas9	negative selection	7876589
4525082	4525105	17	+	27260156	NCIH2009	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.9849011303061682	[748]	[2641,1782,1902]	9	hSpCas9	negative selection	7876590
4536922	4536945	17	+	27260156	NCIH2009	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.5216123336832242	[545]	[1444,1019,888]	7	hSpCas9	negative selection	7876591
4513236	4513259	17	+	27260156	NCIH2009	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.6793348738963996	[533]	[1547,1035,1070]	8	hSpCas9	negative selection	7940844
4531056	4531079	17	-	27260156	NCIH2009	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.23851963180338556	[527]	[842,654,1109]	3	hSpCas9	negative selection	7940845
4531051	4531074	17	+	27260156	NCIH2009	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.22109543000436788	[420]	[623,648,260]	-3	hSpCas9	negative selection	7940846
4525086	4525109	17	-	27260156	NCIH1373	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.6714893696520204	[580]	[1386,785,761,344]	6	hSpCas9	negative selection	7997840
4525082	4525105	17	+	27260156	NCIH1373	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	1.0139772035134897	[748]	[1981,1280,1351,601]	9	hSpCas9	negative selection	7997841
4536922	4536945	17	+	27260156	NCIH1373	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	1.666368692644273	[545]	[1120,1230,1211,1130]	9	hSpCas9	negative selection	7997842
4513236	4513259	17	+	27260156	NCIH1373	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.6757856685501398	[533]	[1097,925,961,223]	6	hSpCas9	negative selection	8062095
4531056	4531079	17	-	27260156	NCIH1373	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.09102201215588308	[527]	[763,545,299,171]	-1	hSpCas9	negative selection	8062096
4531051	4531074	17	+	27260156	NCIH1373	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.07438164389228649	[420]	[415,604,588,88]	0	hSpCas9	negative selection	8062097
4525086	4525109	17	-	27260156	PATU8902	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.3352939102447079	[580]	[668,1408,885,1169]	3	hSpCas9	negative selection	8119091
4525082	4525105	17	+	27260156	PATU8902	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	1.110808903651844	[748]	[2138,2241,2206,2440]	9	hSpCas9	negative selection	8119092
4536922	4536945	17	+	27260156	PATU8902	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.9019535913178919	[545]	[2114,1704,785,1195]	8	hSpCas9	negative selection	8119093
4513236	4513259	17	+	27260156	PATU8902	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.15468214589368887	[533]	[954,638,694,1077]	1	hSpCas9	negative selection	8183346
4531056	4531079	17	-	27260156	PATU8902	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.32846463437581286	[527]	[861,1203,526,1234]	3	hSpCas9	negative selection	8183347
4531051	4531074	17	+	27260156	PATU8902	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.5780820916833193	[420]	[806,1284,817,563]	6	hSpCas9	negative selection	8183348
4525086	4525109	17	-	27260156	PANC1	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.04311260094304581	[580]	[457,746,410,383]	0	hSpCas9	negative selection	8240342
4525082	4525105	17	+	27260156	PANC1	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4473142285424484	[748]	[904,1292,879,554]	7	hSpCas9	negative selection	8240343
4536922	4536945	17	+	27260156	PANC1	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.058259641042020305	[545]	[430,554,389,440]	-1	hSpCas9	negative selection	8240344
4513236	4513259	17	+	27260156	PANC1	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.3488514924707036	[533]	[556,688,595,517]	5	hSpCas9	negative selection	8304597
4531056	4531079	17	-	27260156	PANC1	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.022349806330629135	[527]	[489,563,421,342]	0	hSpCas9	negative selection	8304598
4531051	4531074	17	+	27260156	PANC1	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.42266827908522503	[420]	[302,322,187,269]	-6	hSpCas9	negative selection	8304599
4525086	4525109	17	-	27260156	PANC0813	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.3248214250981549	[580]	[828,993,981,623]	5	hSpCas9	negative selection	8361593
4525082	4525105	17	+	27260156	PANC0813	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.570950510458263	[748]	[1260,1292,1520,1155]	8	hSpCas9	negative selection	8361594
4536922	4536945	17	+	27260156	PANC0813	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.35206111262946416	[545]	[901,923,757,702]	5	hSpCas9	negative selection	8361595
4513236	4513259	17	+	27260156	PANC0813	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.1958966810159354	[533]	[912,619,734,627]	3	hSpCas9	negative selection	8425848
4531056	4531079	17	-	27260156	PANC0813	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.04547050525988336	[527]	[565,525,720,587]	0	hSpCas9	negative selection	8425849
4531051	4531074	17	+	27260156	PANC0813	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.04080967791432788	[420]	[520,509,610,294]	0	hSpCas9	negative selection	8425850
4525086	4525109	17	-	27260156	RDES	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.17811089782092715	[580]	[593,654,793,1049]	3	hSpCas9	negative selection	8482844
4525082	4525105	17	+	27260156	RDES	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.7436141719506905	[748]	[1172,1322,1274,2121]	9	hSpCas9	negative selection	8482845
4536922	4536945	17	+	27260156	RDES	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.4121753589932228	[545]	[626,755,969,1056]	6	hSpCas9	negative selection	8482846
4513236	4513259	17	+	27260156	RDES	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.6099690721164518	[533]	[835,854,1113,952]	8	hSpCas9	negative selection	8547099
4531056	4531079	17	-	27260156	RDES	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.06251672880358147	[527]	[521,362,724,765]	-1	hSpCas9	negative selection	8547100
4531051	4531074	17	+	27260156	RDES	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.04395194128107613	[420]	[365,577,448,483]	0	hSpCas9	negative selection	8547101
4525086	4525109	17	-	27260156	PC3	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	-0.166146674840028	[580]	[381,576,721,456]	-4	hSpCas9	negative selection	8604095
4525082	4525105	17	+	27260156	PC3	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4269216749345647	[748]	[736,953,1393,1091]	8	hSpCas9	negative selection	8604096
4536922	4536945	17	+	27260156	PC3	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.034645532456222705	[545]	[421,522,1033,427]	0	hSpCas9	negative selection	8604097
4513236	4513259	17	+	27260156	PC3	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.34656030964871476	[533]	[455,642,1224,622]	7	hSpCas9	negative selection	8668350
4531056	4531079	17	-	27260156	PC3	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.46633455409798974	[527]	[346,394,438,323]	-8	hSpCas9	negative selection	8668351
4531051	4531074	17	+	27260156	PC3	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.1536350429783946	[420]	[211,367,767,351]	-3	hSpCas9	negative selection	8668352
4525086	4525109	17	-	27260156	PATU8988T	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.17978704546462415	[580]	[735,686,553,566]	3	hSpCas9	negative selection	8725346
4525082	4525105	17	+	27260156	PATU8988T	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.4216298108070059	[748]	[989,1182,664,1071]	7	hSpCas9	negative selection	8725347
4536922	4536945	17	+	27260156	PATU8988T	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.28324670367202864	[545]	[461,319,491,449]	-5	hSpCas9	negative selection	8725348
4513236	4513259	17	+	27260156	PATU8988T	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.507893588554258	[533]	[847,689,823,552]	8	hSpCas9	negative selection	8789601
4531056	4531079	17	-	27260156	PATU8988T	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.38515178512943915	[527]	[299,458,365,448]	-6	hSpCas9	negative selection	8789602
4531051	4531074	17	+	27260156	PATU8988T	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.1288975119817261	[420]	[403,446,287,355]	-2	hSpCas9	negative selection	8789603
4525086	4525109	17	-	27260156	T47D	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.1643471950179261	[580]	[790,741,675,829]	3	hSpCas9	negative selection	8846597
4525082	4525105	17	+	27260156	T47D	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.36140288060185044	[748]	[1054,1125,1034,1272]	7	hSpCas9	negative selection	8846598
4536922	4536945	17	+	27260156	T47D	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.1520177570496286	[545]	[705,737,604,778]	3	hSpCas9	negative selection	8846599
4513236	4513259	17	+	27260156	T47D	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.3895558301641603	[533]	[850,631,915,876]	8	hSpCas9	negative selection	8910852
4531056	4531079	17	-	27260156	T47D	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.10853084434455049	[527]	[618,652,702,677]	2	hSpCas9	negative selection	8910853
4531051	4531074	17	+	27260156	T47D	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	0.049494516105354075	[420]	[618,525,439,442]	1	hSpCas9	negative selection	8910854
4525086	4525109	17	-	27260156	SU8686	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.17560192295199417	[580]	[715,513,641,751]	3	hSpCas9	negative selection	8967848
4525082	4525105	17	+	27260156	SU8686	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.46538233690819963	[748]	[933,899,918,1429]	7	hSpCas9	negative selection	8967849
4536922	4536945	17	+	27260156	SU8686	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.5605951922744005	[545]	[539,831,972,886]	8	hSpCas9	negative selection	8967850
4513236	4513259	17	+	27260156	SU8686	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.608682946983533	[533]	[693,641,1088,846]	8	hSpCas9	negative selection	9032103
4531056	4531079	17	-	27260156	SU8686	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.2605744216489705	[527]	[604,680,590,619]	4	hSpCas9	negative selection	9032104
4531051	4531074	17	+	27260156	SU8686	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.2887050085379612	[420]	[272,305,334,485]	-5	hSpCas9	negative selection	9032105
4525086	4525109	17	-	27260156	SKES1	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.0252408149418481	[580]	[597,683,560,529]	0	hSpCas9	negative selection	9089099
4525082	4525105	17	+	27260156	SKES1	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.44685288936850964	[748]	[1064,1370,864,834]	8	hSpCas9	negative selection	9089100
4536922	4536945	17	+	27260156	SKES1	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.18117840048230016	[545]	[701,737,577,487]	4	hSpCas9	negative selection	9089101
4513236	4513259	17	+	27260156	SKES1	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.46911093948912874	[533]	[920,750,695,615]	8	hSpCas9	negative selection	9153354
4531056	4531079	17	-	27260156	SKES1	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.10387011653752894	[527]	[507,533,454,468]	-2	hSpCas9	negative selection	9153355
4531051	4531074	17	+	27260156	SKES1	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.23267132703975346	[420]	[342,549,321,245]	-5	hSpCas9	negative selection	9153356
4525086	4525109	17	-	27260156	TOV112D	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.029993406427903102	[580]	[592,697,443,663]	0	hSpCas9	negative selection	9210350
4525082	4525105	17	+	27260156	TOV112D	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.5783882898456415	[748]	[1299,1151,833,1212]	9	hSpCas9	negative selection	9210351
4536922	4536945	17	+	27260156	TOV112D	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.11516120394016638	[545]	[731,509,536,580]	2	hSpCas9	negative selection	9210352
4513236	4513259	17	+	27260156	TOV112D	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.5388180866457688	[533]	[891,794,555,874]	8	hSpCas9	negative selection	9274605
4531056	4531079	17	-	27260156	TOV112D	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	-0.508775544406893	[527]	[445,355,479,210]	-7	hSpCas9	negative selection	9274606
4531051	4531074	17	+	27260156	TOV112D	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.48944943282741654	[420]	[271,414,358,183]	-7	hSpCas9	negative selection	9274607
4525086	4525109	17	-	27260156	TC71	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.08598889470976351	[580]	[550,765,631,700]	2	hSpCas9	negative selection	9331601
4525082	4525105	17	+	27260156	TC71	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.31483815392013526	[748]	[981,988,1055,963]	7	hSpCas9	negative selection	9331602
4536922	4536945	17	+	27260156	TC71	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	-0.1661325983095565	[545]	[508,556,503,516]	-4	hSpCas9	negative selection	9331603
4513236	4513259	17	+	27260156	TC71	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.14841087474759848	[533]	[640,709,605,577]	4	hSpCas9	negative selection	9395856
4531056	4531079	17	-	27260156	TC71	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.03849787269711677	[527]	[783,576,563,383]	1	hSpCas9	negative selection	9395857
4531051	4531074	17	+	27260156	TC71	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.2395250567617725	[420]	[377,320,365,469]	-6	hSpCas9	negative selection	9395858
4525086	4525109	17	-	27260156	TC32	viability	TCGCCCAGGTAGCCGAAGATGGG	SPNS2	ENSG00000183018	0.18101126862390815	[580]	[531,410,1014,642]	3	hSpCas9	negative selection	9452852
4525082	4525105	17	+	27260156	TC32	viability	TGCCCCCATCTTCGGCTACCTGG	SPNS2	ENSG00000183018	0.7228803685039177	[748]	[986,1065,1422,1203]	9	hSpCas9	negative selection	9452853
4536922	4536945	17	+	27260156	TC32	viability	CCCGCATCTGTGAAAGTCTGAGG	SPNS2	ENSG00000183018	0.39531744685751835	[545]	[585,668,628,782]	7	hSpCas9	negative selection	9452854
4513236	4513259	17	+	27260156	TC32	viability	CTTCCCTCCAGGCGTCCTTCTGG	SPNS2	ENSG00000183018	0.4964296356654617	[533]	[552,662,838,796]	8	hSpCas9	negative selection	9517107
4531056	4531079	17	-	27260156	TC32	viability	TGGAGCCAGTAATGTAGCCCAGG	SPNS2	ENSG00000183018	0.024819749117933387	[527]	[488,353,687,551]	0	hSpCas9	negative selection	9517108
4531051	4531074	17	+	27260156	TC32	viability	AGTGGCCTGGGCTACATTACTGG	SPNS2	ENSG00000183018	-0.18359371966984123	[420]	[323,278,455,361]	-3	hSpCas9	negative selection	9517109
4499280	4499303	17	-	27869803	HPAFII	viability after 27 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	0.10411423989366542	[87]	[82,21,NaN]	0	hSpCas9	negative selection	9561307
4513243	4513266	17	-	27869803	HPAFII	viability after 27 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.2451739165572837	[115]	[27,70,NaN]	-2	hSpCas9	negative selection	9561322
4525109	4525132	17	-	27869803	HPAFII	viability after 27 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-1.4013196011193683	[131]	[28,23,NaN]	-7	hSpCas9	negative selection	9561324
4530757	4530780	17	+	27869803	HPAFII	viability after 27 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-1.583076487616767	[214]	[34,39,NaN]	-7	hSpCas9	negative selection	9561325
4531076	4531099	17	-	27869803	HPAFII	viability after 27 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.6596327416622205	[368]	[366,255,NaN]	5	hSpCas9	negative selection	9561326
4532631	4532654	17	-	27869803	HPAFII	viability after 27 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.709458470417484	[137]	[146,94,NaN]	6	hSpCas9	negative selection	9561327
4499280	4499303	17	-	27869803	HPAFII	viability after 15 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-0.14266451193965546	[87]	[134,54,NaN]	-2	hSpCas9	negative selection	9643756
4513243	4513266	17	-	27869803	HPAFII	viability after 15 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.03890607643155719	[115]	[137,110,NaN]	0	hSpCas9	negative selection	9643771
4525109	4525132	17	-	27869803	HPAFII	viability after 15 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.2510925873991905	[131]	[174,164,NaN]	3	hSpCas9	negative selection	9643773
4530757	4530780	17	+	27869803	HPAFII	viability after 15 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-0.9340203025069573	[214]	[189,77,NaN]	-7	hSpCas9	negative selection	9643774
4531076	4531099	17	-	27869803	HPAFII	viability after 15 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.47349468778862414	[368]	[541,555,NaN]	5	hSpCas9	negative selection	9643775
4532631	4532654	17	-	27869803	HPAFII	viability after 15 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.9340047206742053	[137]	[410,203,NaN]	8	hSpCas9	negative selection	9643776
4499280	4499303	17	-	27869803	ASPC1	viability after 36 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-0.8309364639701511	[196]	[57,36,25]	-7	hSpCas9	negative selection	9726205
4513243	4513266	17	-	27869803	ASPC1	viability after 36 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.7354620504836089	[328]	[216,48,283]	7	hSpCas9	negative selection	9726220
4525109	4525132	17	-	27869803	ASPC1	viability after 36 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.5036269476920412	[513]	[214,279,258]	5	hSpCas9	negative selection	9726222
4530757	4530780	17	+	27869803	ASPC1	viability after 36 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.7001340519813393	[469]	[261,302,237]	7	hSpCas9	negative selection	9726223
4531076	4531099	17	-	27869803	ASPC1	viability after 36 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.21107419399599314	[1099]	[118,650,223]	-2	hSpCas9	negative selection	9726224
4532631	4532654	17	-	27869803	ASPC1	viability after 36 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.005119809591853985	[368]	[116,173,100]	0	hSpCas9	negative selection	9726225
4499280	4499303	17	-	27869803	PATU8988S	viability after 35 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-1.12782743941645	[140]	[19,31,NaN]	-8	hSpCas9	negative selection	9808654
4513243	4513266	17	-	27869803	PATU8988S	viability after 35 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.20189849767988077	[215]	[126,72,NaN]	2	hSpCas9	negative selection	9808669
4525109	4525132	17	-	27869803	PATU8988S	viability after 35 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.018135720715019954	[445]	[125,228,NaN]	0	hSpCas9	negative selection	9808671
4530757	4530780	17	+	27869803	PATU8988S	viability after 35 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.24720809713584535	[506]	[180,303,NaN]	3	hSpCas9	negative selection	9808672
4531076	4531099	17	-	27869803	PATU8988S	viability after 35 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.20002795573461019	[1044]	[315,416,NaN]	-2	hSpCas9	negative selection	9808673
4532631	4532654	17	-	27869803	PATU8988S	viability after 35 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.14480935588474775	[371]	[141,128,NaN]	-1	hSpCas9	negative selection	9808674
4499280	4499303	17	-	27869803	PATU8988S	viability after 31 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-1.309862364665766	[140]	[12,34,NaN]	-8	hSpCas9	negative selection	9891103
4513243	4513266	17	-	27869803	PATU8988S	viability after 31 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.31472726610422264	[215]	[129,77,NaN]	4	hSpCas9	negative selection	9891118
4525109	4525132	17	-	27869803	PATU8988S	viability after 31 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	0.30473944581659473	[445]	[154,301,NaN]	4	hSpCas9	negative selection	9891120
4530757	4530780	17	+	27869803	PATU8988S	viability after 31 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	0.32379984483015584	[506]	[212,303,NaN]	4	hSpCas9	negative selection	9891121
4531076	4531099	17	-	27869803	PATU8988S	viability after 31 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	-0.3741501959400524	[1044]	[218,451,NaN]	-4	hSpCas9	negative selection	9891122
4532631	4532654	17	-	27869803	PATU8988S	viability after 31 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	-0.44399716403089795	[371]	[101,117,NaN]	-5	hSpCas9	negative selection	9891123
4499280	4499303	17	-	27869803	HPAFII	viability after 35 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	0.41291520256719383	[87]	[95,17,NaN]	2	hSpCas9	negative selection	9973552
4513243	4513266	17	-	27869803	HPAFII	viability after 35 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	0.15679036968788818	[115]	[56,74,NaN]	1	hSpCas9	negative selection	9973567
4525109	4525132	17	-	27869803	HPAFII	viability after 35 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.7636588409900391	[131]	[52,23,NaN]	-4	hSpCas9	negative selection	9973569
4530757	4530780	17	+	27869803	HPAFII	viability after 35 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-1.5815229192989195	[214]	[65,2,NaN]	-7	hSpCas9	negative selection	9973570
4531076	4531099	17	-	27869803	HPAFII	viability after 35 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	1.1042440447992907	[368]	[434,363,NaN]	7	hSpCas9	negative selection	9973571
4532631	4532654	17	-	27869803	HPAFII	viability after 35 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.6832083244969167	[137]	[114,108,NaN]	4	hSpCas9	negative selection	9973572
4499280	4499303	17	-	27869803	HPAFII	viability after 31 days	CTTTGCAGTAGCTGCGCAGCCGG	SPNS2	ENSG00000183018	-0.19024135754669258	[87]	[71,11,NaN]	-1	hSpCas9	negative selection	10056001
4513243	4513266	17	-	27869803	HPAFII	viability after 31 days	TGGATGTCCAGAAGGACGCCTGG	SPNS2	ENSG00000183018	-0.7257944005647752	[115]	[13,66,NaN]	-5	hSpCas9	negative selection	10056016
4525109	4525132	17	-	27869803	HPAFII	viability after 31 days	GAATCACCTTCCTGTTGAAGCGG	SPNS2	ENSG00000183018	-0.3268087823364574	[131]	[93,20,NaN]	-2	hSpCas9	negative selection	10056018
4530757	4530780	17	+	27869803	HPAFII	viability after 31 days	CTTCTACTTCGCCATCCCACTGG	SPNS2	ENSG00000183018	-1.8346513012302192	[214]	[29,37,NaN]	-8	hSpCas9	negative selection	10056019
4531076	4531099	17	-	27869803	HPAFII	viability after 31 days	TCCGGCTGCCTGCTTCACGCTGG	SPNS2	ENSG00000183018	0.6182261493599241	[368]	[303,332,NaN]	4	hSpCas9	negative selection	10056020
4532631	4532654	17	-	27869803	HPAFII	viability after 31 days	ATGAGGTCCGGGCCTTGAGCTGG	SPNS2	ENSG00000183018	0.38458785474523155	[137]	[136,61,NaN]	2	hSpCas9	negative selection	10056021
4525159	4525182	17	-	28162770	P31FUJ	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-7.4807297178579635	[151]	[0]	-9	hSpCas9	negative selection	10242191
4536406	4536429	17	-	28162770	P31FUJ	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-0.5608564020985825	[58]	[46]	-5	hSpCas9	negative selection	10242192
4499358	4499381	17	-	28162770	P31FUJ	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.8984423288638741	[20]	[45]	8	hSpCas9	negative selection	10242193
4499392	4499415	17	+	28162770	P31FUJ	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.766234404495453	[54]	[37]	-5	hSpCas9	negative selection	10242194
4532977	4533000	17	-	28162770	P31FUJ	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-0.8375473173260726	[256]	[168]	-6	hSpCas9	negative selection	10242195
4533033	4533056	17	-	28162770	P31FUJ	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.2924570093077522	[394]	[378]	-3	hSpCas9	negative selection	10242196
4533314	4533337	17	+	28162770	P31FUJ	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.16871415521084637	[267]	[353]	1	hSpCas9	negative selection	10242197
4533343	4533366	17	-	28162770	P31FUJ	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.25188306784830583	[277]	[388]	2	hSpCas9	negative selection	10242198
4533377	4533400	17	-	28162770	P31FUJ	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.018905783746625104	[340]	[405]	0	hSpCas9	negative selection	10242199
4536381	4536404	17	-	28162770	P31FUJ	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-1.268935990468092	[282]	[137]	-7	hSpCas9	negative selection	10242200
4525159	4525182	17	-	28162770	TF1	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10411557
4536406	4536429	17	-	28162770	TF1	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10411558
4499358	4499381	17	-	28162770	TF1	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10411559
4499392	4499415	17	+	28162770	TF1	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10411560
4532977	4533000	17	-	28162770	TF1	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	NaN	[NaN]	[279]	1	hSpCas9	negative selection	10411561
4533033	4533056	17	-	28162770	TF1	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10411562
4533314	4533337	17	+	28162770	TF1	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10411563
4533343	4533366	17	-	28162770	TF1	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	NaN	[NaN]	[290]	1	hSpCas9	negative selection	10411564
4533377	4533400	17	-	28162770	TF1	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	NaN	[NaN]	[415]	1	hSpCas9	negative selection	10411565
4536381	4536404	17	-	28162770	TF1	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10411566
4525159	4525182	17	-	28162770	SKM1	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.3765905496996425	[46]	[0]	-9	hSpCas9	negative selection	10580923
4536406	4536429	17	-	28162770	SKM1	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.07846262842708018	[14]	[27]	0	hSpCas9	negative selection	10580924
4499358	4499381	17	-	28162770	SKM1	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.0259952085329442	[4]	[17]	8	hSpCas9	negative selection	10580925
4499392	4499415	17	+	28162770	SKM1	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.014499569695115122	[13]	[24]	0	hSpCas9	negative selection	10580926
4532977	4533000	17	-	28162770	SKM1	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.34559825047406306	[68]	[154]	3	hSpCas9	negative selection	10580927
4533033	4533056	17	-	28162770	SKM1	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.8162028239761303	[132]	[413]	7	hSpCas9	negative selection	10580928
4533314	4533337	17	+	28162770	SKM1	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.3428338613234462	[65]	[91]	-3	hSpCas9	negative selection	10580929
4533343	4533366	17	-	28162770	SKM1	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.3365748708517637	[54]	[76]	-3	hSpCas9	negative selection	10580930
4533377	4533400	17	-	28162770	SKM1	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.1779983019779946	[91]	[183]	1	hSpCas9	negative selection	10580931
4536381	4536404	17	-	28162770	SKM1	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.5108000097277017	[53]	[66]	-4	hSpCas9	negative selection	10580932
4525159	4525182	17	-	28162770	SKM1	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.3765905496996425	[46]	[0]	-9	hSpCas9	negative selection	10750289
4536406	4536429	17	-	28162770	SKM1	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.07846262842708018	[14]	[27]	0	hSpCas9	negative selection	10750290
4499358	4499381	17	-	28162770	SKM1	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.0259952085329442	[4]	[17]	8	hSpCas9	negative selection	10750291
4499392	4499415	17	+	28162770	SKM1	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.014499569695115122	[13]	[24]	0	hSpCas9	negative selection	10750292
4532977	4533000	17	-	28162770	SKM1	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.34559825047406306	[68]	[154]	3	hSpCas9	negative selection	10750293
4533033	4533056	17	-	28162770	SKM1	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.8162028239761303	[132]	[413]	7	hSpCas9	negative selection	10750294
4533314	4533337	17	+	28162770	SKM1	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.3428338613234462	[65]	[91]	-3	hSpCas9	negative selection	10750295
4533343	4533366	17	-	28162770	SKM1	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.3365748708517637	[54]	[76]	-3	hSpCas9	negative selection	10750296
4533377	4533400	17	-	28162770	SKM1	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.1779983019779946	[91]	[183]	1	hSpCas9	negative selection	10750297
4536381	4536404	17	-	28162770	SKM1	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.5108000097277017	[53]	[66]	-4	hSpCas9	negative selection	10750298
4525159	4525182	17	-	28162770	PL21	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.121788480398043	[159]	[0]	-9	hSpCas9	negative selection	10919655
4536406	4536429	17	-	28162770	PL21	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.9777471931528723	[27]	[23]	7	hSpCas9	negative selection	10919656
4499358	4499381	17	-	28162770	PL21	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.13866229896243798	[42]	[16]	-1	hSpCas9	negative selection	10919657
4499392	4499415	17	+	28162770	PL21	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	1.1697659654458012	[47]	[46]	8	hSpCas9	negative selection	10919658
4532977	4533000	17	-	28162770	PL21	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-1.429910775760374	[259]	[41]	-7	hSpCas9	negative selection	10919659
4533033	4533056	17	-	28162770	PL21	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.7630683541410442	[541]	[138]	-5	hSpCas9	negative selection	10919660
4533314	4533337	17	+	28162770	PL21	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.18534261256123938	[195]	[96]	1	hSpCas9	negative selection	10919661
4533343	4533366	17	-	28162770	PL21	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.8479546737117251	[243]	[58]	-5	hSpCas9	negative selection	10919662
4533377	4533400	17	-	28162770	PL21	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.4504067242492362	[226]	[134]	4	hSpCas9	negative selection	10919663
4536381	4536404	17	-	28162770	PL21	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	0.1718505700578964	[205]	[100]	1	hSpCas9	negative selection	10919664
4525159	4525182	17	-	28162770	P31FUJ	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-7.4807297178579635	[151]	[0]	-9	hSpCas9	negative selection	11089021
4536406	4536429	17	-	28162770	P31FUJ	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-0.5608564020985825	[58]	[46]	-5	hSpCas9	negative selection	11089022
4499358	4499381	17	-	28162770	P31FUJ	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.8984423288638741	[20]	[45]	8	hSpCas9	negative selection	11089023
4499392	4499415	17	+	28162770	P31FUJ	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.766234404495453	[54]	[37]	-5	hSpCas9	negative selection	11089024
4532977	4533000	17	-	28162770	P31FUJ	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-0.8375473173260726	[256]	[168]	-6	hSpCas9	negative selection	11089025
4533033	4533056	17	-	28162770	P31FUJ	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.2924570093077522	[394]	[378]	-3	hSpCas9	negative selection	11089026
4533314	4533337	17	+	28162770	P31FUJ	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.16871415521084637	[267]	[353]	1	hSpCas9	negative selection	11089027
4533343	4533366	17	-	28162770	P31FUJ	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.25188306784830583	[277]	[388]	2	hSpCas9	negative selection	11089028
4533377	4533400	17	-	28162770	P31FUJ	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.018905783746625104	[340]	[405]	0	hSpCas9	negative selection	11089029
4536381	4536404	17	-	28162770	P31FUJ	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-1.268935990468092	[282]	[137]	-7	hSpCas9	negative selection	11089030
4525159	4525182	17	-	28162770	OCIAML5	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.8293464943639135	[62]	[0]	-9	hSpCas9	negative selection	11258387
4536406	4536429	17	-	28162770	OCIAML5	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-1.4370290715851533	[11]	[7]	-7	hSpCas9	negative selection	11258388
4499358	4499381	17	-	28162770	OCIAML5	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.8520665708639967	[18]	[18]	-5	hSpCas9	negative selection	11258389
4499392	4499415	17	+	28162770	OCIAML5	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.4687379313124911	[22]	[29]	-3	hSpCas9	negative selection	11258390
4532977	4533000	17	-	28162770	OCIAML5	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.6675421918630595	[142]	[409]	6	hSpCas9	negative selection	11258391
4533033	4533056	17	-	28162770	OCIAML5	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.15353613536537902	[256]	[515]	1	hSpCas9	negative selection	11258392
4533314	4533337	17	+	28162770	OCIAML5	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.4759876268202069	[93]	[235]	4	hSpCas9	negative selection	11258393
4533343	4533366	17	-	28162770	OCIAML5	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.6004456338335098	[151]	[415]	5	hSpCas9	negative selection	11258394
4533377	4533400	17	-	28162770	OCIAML5	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	-0.03723652824424617	[219]	[386]	0	hSpCas9	negative selection	11258395
4536381	4536404	17	-	28162770	OCIAML5	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.8111942894484689	[173]	[178]	-5	hSpCas9	negative selection	11258396
4525159	4525182	17	-	28162770	EOL1	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-7.467769651208226	[335]	[0]	-9	hSpCas9	negative selection	11427753
4536406	4536429	17	-	28162770	EOL1	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	0.40517361247695494	[42]	[29]	3	hSpCas9	negative selection	11427754
4499358	4499381	17	-	28162770	EOL1	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.8719188343443331	[65]	[18]	-6	hSpCas9	negative selection	11427755
4499392	4499415	17	+	28162770	EOL1	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.2724710749908412	[76]	[48]	2	hSpCas9	negative selection	11427756
4532977	4533000	17	-	28162770	EOL1	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	1.1624575832487125	[501]	[591]	8	hSpCas9	negative selection	11427757
4533033	4533056	17	-	28162770	EOL1	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.007586198148322065	[871]	[456]	0	hSpCas9	negative selection	11427758
4533314	4533337	17	+	28162770	EOL1	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.6404878622736152	[234]	[192]	6	hSpCas9	negative selection	11427759
4533343	4533366	17	-	28162770	EOL1	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.4509156183808425	[267]	[192]	4	hSpCas9	negative selection	11427760
4533377	4533400	17	-	28162770	EOL1	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	1.577276828568709	[401]	[631]	9	hSpCas9	negative selection	11427761
4536381	4536404	17	-	28162770	EOL1	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	0.4020258456252854	[259]	[180]	3	hSpCas9	negative selection	11427762
4525159	4525182	17	-	28162770	MOLM13	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-7.420853867353681	[236]	[0]	-9	hSpCas9	negative selection	11597119
4536406	4536429	17	-	28162770	MOLM13	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-0.3097181971189731	[83]	[48]	-2	hSpCas9	negative selection	11597120
4499358	4499381	17	-	28162770	MOLM13	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.6764760033559964	[44]	[103]	9	hSpCas9	negative selection	11597121
4499392	4499415	17	+	28162770	MOLM13	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	-0.22544928022136967	[75]	[46]	-1	hSpCas9	negative selection	11597122
4532977	4533000	17	-	28162770	MOLM13	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.9250523564960992	[404]	[555]	7	hSpCas9	negative selection	11597123
4533033	4533056	17	-	28162770	MOLM13	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.25102188813181403	[694]	[597]	1	hSpCas9	negative selection	11597124
4533314	4533337	17	+	28162770	MOLM13	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-1.449015002691959	[252]	[66]	-6	hSpCas9	negative selection	11597125
4533343	4533366	17	-	28162770	MOLM13	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.8782198781458951	[306]	[407]	6	hSpCas9	negative selection	11597126
4533377	4533400	17	-	28162770	MOLM13	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.10958889699225438	[481]	[375]	0	hSpCas9	negative selection	11597127
4536381	4536404	17	-	28162770	MOLM13	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-1.8445472643654859	[302]	[60]	-7	hSpCas9	negative selection	11597128
4525159	4525182	17	-	28162770	HEL	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.942223668720799	[191]	[0]	-9	hSpCas9	negative selection	11766485
4536406	4536429	17	-	28162770	HEL	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	2.3706592865635563	[31]	[105]	9	hSpCas9	negative selection	11766486
4499358	4499381	17	-	28162770	HEL	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	1.642738832000357	[17]	[35]	9	hSpCas9	negative selection	11766487
4499392	4499415	17	+	28162770	HEL	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.2454033344549722	[53]	[40]	2	hSpCas9	negative selection	11766488
4532977	4533000	17	-	28162770	HEL	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-0.25034596408313126	[337]	[181]	-2	hSpCas9	negative selection	11766489
4533033	4533056	17	-	28162770	HEL	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.8654859417321721	[580]	[677]	7	hSpCas9	negative selection	11766490
4533314	4533337	17	+	28162770	HEL	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.1798649171261956	[213]	[120]	-1	hSpCas9	negative selection	11766491
4533343	4533366	17	-	28162770	HEL	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.15183748533594443	[280]	[161]	-1	hSpCas9	negative selection	11766492
4533377	4533400	17	-	28162770	HEL	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.28131012533411215	[360]	[280]	2	hSpCas9	negative selection	11766493
4536381	4536404	17	-	28162770	HEL	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.27256400342436177	[214]	[113]	-2	hSpCas9	negative selection	11766494
4525159	4525182	17	-	28162770	MV411	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-7.329991277252973	[190]	[0]	-9	hSpCas9	negative selection	11935851
4536406	4536429	17	-	28162770	MV411	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-0.6594530448257432	[44]	[23]	-5	hSpCas9	negative selection	11935852
4499358	4499381	17	-	28162770	MV411	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.2118136410520539	[40]	[39]	1	hSpCas9	negative selection	11935853
4499392	4499415	17	+	28162770	MV411	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.9941511215005437	[58]	[98]	8	hSpCas9	negative selection	11935854
4532977	4533000	17	-	28162770	MV411	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.5025667585312229	[304]	[363]	4	hSpCas9	negative selection	11935855
4533033	4533056	17	-	28162770	MV411	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.6186731946834083	[544]	[298]	-4	hSpCas9	negative selection	11935856
4533314	4533337	17	+	28162770	MV411	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.2204518307618034	[277]	[200]	-2	hSpCas9	negative selection	11935857
4533343	4533366	17	-	28162770	MV411	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.19780678305817473	[206]	[199]	1	hSpCas9	negative selection	11935858
4533377	4533400	17	-	28162770	MV411	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	-0.30861225802314196	[246]	[167]	-2	hSpCas9	negative selection	11935859
4536381	4536404	17	-	28162770	MV411	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.6828534774058204	[201]	[105]	-5	hSpCas9	negative selection	11935860
4525159	4525182	17	-	28162770	MONOMAC1	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-3.47005534146597	[115]	[11]	-9	hSpCas9	negative selection	12105217
4536406	4536429	17	-	28162770	MONOMAC1	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	-1.4380449465633487	[25]	[10]	-8	hSpCas9	negative selection	12105218
4499358	4499381	17	-	28162770	MONOMAC1	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.35935650146483145	[16]	[24]	3	hSpCas9	negative selection	12105219
4499392	4499415	17	+	28162770	MONOMAC1	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	1.2659351292829921	[36]	[101]	9	hSpCas9	negative selection	12105220
4532977	4533000	17	-	28162770	MONOMAC1	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.09442596710075779	[200]	[245]	1	hSpCas9	negative selection	12105221
4533033	4533056	17	-	28162770	MONOMAC1	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	0.2489815955524528	[333]	[454]	2	hSpCas9	negative selection	12105222
4533314	4533337	17	+	28162770	MONOMAC1	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	0.5166589677838054	[149]	[245]	5	hSpCas9	negative selection	12105223
4533343	4533366	17	-	28162770	MONOMAC1	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.5266319244931946	[108]	[179]	5	hSpCas9	negative selection	12105224
4533377	4533400	17	-	28162770	MONOMAC1	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.38113648799896327	[141]	[211]	4	hSpCas9	negative selection	12105225
4536381	4536404	17	-	28162770	MONOMAC1	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-0.06152187640307268	[131]	[144]	0	hSpCas9	negative selection	12105226
4525159	4525182	17	-	28162770	OCIAML2	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-6.0555923259633175	[35]	[2]	-9	hSpCas9	negative selection	12274583
4536406	4536429	17	-	28162770	OCIAML2	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	1.8392254373446262	[5]	[118]	9	hSpCas9	negative selection	12274584
4499358	4499381	17	-	28162770	OCIAML2	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	-0.8856673245210049	[7]	[23]	-6	hSpCas9	negative selection	12274585
4499392	4499415	17	+	28162770	OCIAML2	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.455369593314062	[9]	[75]	4	hSpCas9	negative selection	12274586
4532977	4533000	17	-	28162770	OCIAML2	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	0.2803426269179241	[40]	[275]	2	hSpCas9	negative selection	12274587
4533033	4533056	17	-	28162770	OCIAML2	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.17269721142377725	[96]	[476]	-1	hSpCas9	negative selection	12274588
4533314	4533337	17	+	28162770	OCIAML2	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.47062982524216146	[27]	[111]	-4	hSpCas9	negative selection	12274589
4533343	4533366	17	-	28162770	OCIAML2	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	-0.45940256981890715	[31]	[128]	-4	hSpCas9	negative selection	12274590
4533377	4533400	17	-	28162770	OCIAML2	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	-0.4780093556077587	[48]	[194]	-4	hSpCas9	negative selection	12274591
4536381	4536404	17	-	28162770	OCIAML2	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-1.037670417966055	[39]	[107]	-6	hSpCas9	negative selection	12274592
4525159	4525182	17	-	28162770	OCIAML3	viability	GAAGGAGCTGGAGAAGGTGACGG	SPNS2	ENSG00000183018	-5.594007640324163	[31]	[1]	-9	hSpCas9	negative selection	12443949
4536406	4536429	17	-	28162770	OCIAML3	viability	ACTGCTGCTCAGCCCTGGCGCGG	SPNS2	ENSG00000183018	1.505528033226751	[13]	[119]	9	hSpCas9	negative selection	12443950
4499358	4499381	17	-	28162770	OCIAML3	viability	GCCCAAGCTGAGGATGGCGGCGG	SPNS2	ENSG00000183018	0.1715271060388135	[4]	[16]	1	hSpCas9	negative selection	12443951
4499392	4499415	17	+	28162770	OCIAML3	viability	CTACCTGGACAGGTACACCGTGG	SPNS2	ENSG00000183018	0.11871040759536577	[17]	[58]	1	hSpCas9	negative selection	12443952
4532977	4533000	17	-	28162770	OCIAML3	viability	GGGAGGAGAAGACGTAGCTGCGG	SPNS2	ENSG00000183018	-0.49743438062911016	[64]	[138]	-4	hSpCas9	negative selection	12443953
4533033	4533056	17	-	28162770	OCIAML3	viability	GAGCGGGATCCACATGCCCAGGG	SPNS2	ENSG00000183018	-0.03419861683134551	[134]	[397]	0	hSpCas9	negative selection	12443954
4533314	4533337	17	+	28162770	OCIAML3	viability	GGTGCCGCCTGAAGACCCAGCGG	SPNS2	ENSG00000183018	-0.3716152189877152	[59]	[139]	-3	hSpCas9	negative selection	12443955
4533343	4533366	17	-	28162770	OCIAML3	viability	ATGCCCACGGCACACACCAGTGG	SPNS2	ENSG00000183018	0.33199177823205983	[39]	[151]	3	hSpCas9	negative selection	12443956
4533377	4533400	17	-	28162770	OCIAML3	viability	GAAGATCAGGCAGATGAAGATGG	SPNS2	ENSG00000183018	0.6066141583410656	[61]	[284]	5	hSpCas9	negative selection	12443957
4536381	4536404	17	-	28162770	OCIAML3	viability	GCTGACGAAGAAGAGCGCAGTGG	SPNS2	ENSG00000183018	-1.2196121255426653	[53]	[69]	-7	hSpCas9	negative selection	12443958