Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 201305
• Symbol: SPNS3
• Description: SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)

DataSource: http://genomecrispr.dkfz.de/#!/results/SPNS3

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4448174	4448197	17	-	26472758	Jiyoye	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.8407521319377121	[75]	[31]	-5	hSpCas9	negative selection	155452
4434110	4434133	17	-	26472758	Jiyoye	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	1.1727101278688505	[139]	[237]	7	hSpCas9	negative selection	155453
4439659	4439682	17	+	26472758	Jiyoye	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.2223057859939273	[180]	[116]	-1	hSpCas9	negative selection	155454
4446118	4446141	17	-	26472758	Jiyoye	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.4665539285848051	[118]	[123]	3	hSpCas9	negative selection	155455
4448200	4448223	17	+	26472758	Jiyoye	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	1.1690156443111088	[91]	[155]	7	hSpCas9	negative selection	155456
4448219	4448242	17	+	26472758	Jiyoye	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	1.1816156810907423	[37]	[64]	7	hSpCas9	negative selection	155457
4453151	4453174	17	-	26472758	Jiyoye	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-2.3116428659500734	[157]	[23]	-8	hSpCas9	negative selection	155458
4434053	4434076	17	-	26472758	Jiyoye	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	0.05103157128059799	[31]	[24]	0	hSpCas9	negative selection	155459
4448174	4448197	17	-	26472758	KBM7	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.1712297455163826	[378,260]	[184,150]	1	hSpCas9	negative selection	346570
4434110	4434133	17	-	26472758	KBM7	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.5205493297252981	[1260,819]	[319,348]	-4	hSpCas9	negative selection	346571
4439659	4439682	17	+	26472758	KBM7	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.15896699254024121	[503,608]	[326,268]	1	hSpCas9	negative selection	346572
4446118	4446141	17	-	26472758	KBM7	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.4538833417826733	[409,242]	[152,252]	5	hSpCas9	negative selection	346573
4448200	4448223	17	+	26472758	KBM7	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.577323964921191	[468,305]	[364,179]	6	hSpCas9	negative selection	346574
4448219	4448242	17	+	26472758	KBM7	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.23396041426002423	[211,124]	[87,93]	2	hSpCas9	negative selection	346575
4453151	4453174	17	-	26472758	KBM7	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.39215398416203723	[310,401]	[215,230]	4	hSpCas9	negative selection	346576
4434053	4434076	17	-	26472758	KBM7	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.1684012458213648	[430,114]	[34,70]	-7	hSpCas9	negative selection	346577
4448174	4448197	17	-	26472758	Raji	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.05795419657306111	[156]	[34]	0	hSpCas9	negative selection	537688
4434110	4434133	17	-	26472758	Raji	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.01629083501295614	[352]	[80]	0	hSpCas9	negative selection	537689
4439659	4439682	17	+	26472758	Raji	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.5004784817717665	[264]	[86]	5	hSpCas9	negative selection	537690
4446118	4446141	17	-	26472758	Raji	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	1.5794519796888222	[123]	[85]	9	hSpCas9	negative selection	537691
4448200	4448223	17	+	26472758	Raji	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.30234619620939474	[310]	[88]	3	hSpCas9	negative selection	537692
4448219	4448242	17	+	26472758	Raji	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.742386718594351	[84]	[32]	7	hSpCas9	negative selection	537693
4453151	4453174	17	-	26472758	Raji	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-0.19796167531815861	[172]	[34]	-2	hSpCas9	negative selection	537694
4434053	4434076	17	-	26472758	Raji	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.4091919903673067	[102]	[8]	-7	hSpCas9	negative selection	537695
4448174	4448197	17	-	26472758	K562	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.11626237617576463	[199]	[182]	0	hSpCas9	negative selection	728806
4434110	4434133	17	-	26472758	K562	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.23863637507244084	[749]	[746]	1	hSpCas9	negative selection	728807
4439659	4439682	17	+	26472758	K562	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.4660151793049718	[517]	[603]	3	hSpCas9	negative selection	728808
4446118	4446141	17	-	26472758	K562	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	-0.871058489753489	[363]	[167]	-5	hSpCas9	negative selection	728809
4448200	4448223	17	+	26472758	K562	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.39247156509857023	[296]	[190]	-3	hSpCas9	negative selection	728810
4448219	4448242	17	+	26472758	K562	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.6059268305284954	[150]	[193]	5	hSpCas9	negative selection	728811
4453151	4453174	17	-	26472758	K562	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-1.5856562708912407	[351]	[98]	-7	hSpCas9	negative selection	728812
4434053	4434076	17	-	26472758	K562	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-2.121903486579369	[164]	[31]	-7	hSpCas9	negative selection	728813
4434087	4434110	17	-	26627737	DLD1	viability	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.24015903997756502	[482]	[226,99,200]	2	hSpCas9	negative selection	798265
4439659	4439682	17	+	26627737	DLD1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.18840438853368652	[635]	[114,287,131]	-2	hSpCas9	negative selection	798266
4445118	4445141	17	+	26627737	DLD1	viability	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.4867982508669655	[387]	[156,296,75]	5	hSpCas9	negative selection	798272
4446125	4446148	17	-	26627737	DLD1	viability	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.9836046408646658	[327]	[197,239,175]	8	hSpCas9	negative selection	798274
4446955	4446978	17	-	26627737	DLD1	viability	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.40415460355255894	[230]	[55,133,97]	4	hSpCas9	negative selection	798275
4448198	4448221	17	+	26627737	DLD1	viability	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.2028242897756456	[929]	[265,295,204]	-2	hSpCas9	negative selection	798276
4434087	4434110	17	-	26627737	GBM cells	viability after 5 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.0009857841455556682	[340]	[167,197]	0	hSpCas9	negative selection	880580
4439659	4439682	17	+	26627737	GBM cells	viability after 5 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.2942694216941367	[382]	[158,175]	-4	hSpCas9	negative selection	880581
4445118	4445141	17	+	26627737	GBM cells	viability after 5 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.0022536245783700837	[201]	[105,110]	0	hSpCas9	negative selection	880587
4446125	4446148	17	-	26627737	GBM cells	viability after 5 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.323562968948821	[186]	[134,115]	5	hSpCas9	negative selection	880589
4446955	4446978	17	-	26627737	GBM cells	viability after 5 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.4041491831361078	[154]	[118,100]	6	hSpCas9	negative selection	880590
4448198	4448221	17	+	26627737	GBM cells	viability after 5 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.31482441203739775	[412]	[286,263]	5	hSpCas9	negative selection	880591
4434087	4434110	17	-	26627737	GBM cells	viability after 13 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.12815635149068233	[340]	[199,203]	1	hSpCas9	negative selection	962895
4439659	4439682	17	+	26627737	GBM cells	viability after 13 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.7633257427508622	[382]	[149,99]	-7	hSpCas9	negative selection	962896
4445118	4445141	17	+	26627737	GBM cells	viability after 13 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	-0.05510972422406246	[201]	[126,87]	0	hSpCas9	negative selection	962902
4446125	4446148	17	-	26627737	GBM cells	viability after 13 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.33222205989436404	[186]	[151,107]	4	hSpCas9	negative selection	962904
4446955	4446978	17	-	26627737	GBM cells	viability after 13 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.32436049254835275	[154]	[160,59]	4	hSpCas9	negative selection	962905
4448198	4448221	17	+	26627737	GBM cells	viability after 13 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.209349670698458	[412]	[243,152]	-3	hSpCas9	negative selection	962906
4434087	4434110	17	-	26627737	GBM cells	viability after 21 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.7430916969630477	[340]	[319,300]	7	hSpCas9	negative selection	1045210
4439659	4439682	17	+	26627737	GBM cells	viability after 21 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.5539319963867123	[382]	[147,135]	-5	hSpCas9	negative selection	1045211
4445118	4445141	17	+	26627737	GBM cells	viability after 21 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	-0.6769071238381734	[201]	[76,60]	-5	hSpCas9	negative selection	1045217
4446125	4446148	17	-	26627737	GBM cells	viability after 21 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.019762491343478406	[186]	[106,93]	0	hSpCas9	negative selection	1045219
4446955	4446978	17	-	26627737	GBM cells	viability after 21 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.14522423032695475	[154]	[60,89]	-1	hSpCas9	negative selection	1045220
4448198	4448221	17	+	26627737	GBM cells	viability after 21 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.18156820380325267	[412]	[266,242]	2	hSpCas9	negative selection	1045221
4434087	4434110	17	-	26627737	RPE1	viability after 9 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	3.018770643511442	[170]	[315,585]	9	hSpCas9	negative selection	1127525
4439659	4439682	17	+	26627737	RPE1	viability after 9 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.02615966724784774	[894]	[290,277]	0	hSpCas9	negative selection	1127526
4445118	4445141	17	+	26627737	RPE1	viability after 9 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	3.4408159634333524	[93]	[257,398]	9	hSpCas9	negative selection	1127532
4446125	4446148	17	-	26627737	RPE1	viability after 9 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.36600952755776084	[591]	[292,168]	2	hSpCas9	negative selection	1127534
4446955	4446978	17	-	26627737	RPE1	viability after 9 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.7418310661694796	[465]	[81,93]	-5	hSpCas9	negative selection	1127535
4448198	4448221	17	+	26627737	RPE1	viability after 9 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.2307415746462536	[974]	[324,400]	1	hSpCas9	negative selection	1127536
4434087	4434110	17	-	26627737	RPE1	viability after 12 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	3.0444216903796555	[170]	[294,467]	9	hSpCas9	negative selection	1209840
4439659	4439682	17	+	26627737	RPE1	viability after 12 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.12958488441661214	[894]	[178,262]	-1	hSpCas9	negative selection	1209841
4445118	4445141	17	+	26627737	RPE1	viability after 12 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	2.632989301347333	[93]	[127,186]	9	hSpCas9	negative selection	1209847
4446125	4446148	17	-	26627737	RPE1	viability after 12 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.1157957423678857	[591]	[234,105]	0	hSpCas9	negative selection	1209849
4446955	4446978	17	-	26627737	RPE1	viability after 12 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.282775284019833	[465]	[82,123]	-2	hSpCas9	negative selection	1209850
4448198	4448221	17	+	26627737	RPE1	viability after 12 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.02970865824215524	[974]	[229,306]	0	hSpCas9	negative selection	1209851
4434087	4434110	17	-	26627737	RPE1	viability after 15 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	2.40033469880821	[170]	[93,410]	9	hSpCas9	negative selection	1292155
4439659	4439682	17	+	26627737	RPE1	viability after 15 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.2290017216998792	[894]	[186,243]	-1	hSpCas9	negative selection	1292156
4445118	4445141	17	+	26627737	RPE1	viability after 15 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	3.235592256255919	[93]	[308,193]	9	hSpCas9	negative selection	1292162
4446125	4446148	17	-	26627737	RPE1	viability after 15 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.4122583459729091	[591]	[230,214]	2	hSpCas9	negative selection	1292164
4446955	4446978	17	-	26627737	RPE1	viability after 15 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.21158154220177294	[465]	[150,77]	-1	hSpCas9	negative selection	1292165
4448198	4448221	17	+	26627737	RPE1	viability after 15 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.10883032146892496	[974]	[273,319]	0	hSpCas9	negative selection	1292166
4434087	4434110	17	-	26627737	RPE1	viability after 18 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	3.228190252124522	[170]	[357,511]	9	hSpCas9	negative selection	1374470
4439659	4439682	17	+	26627737	RPE1	viability after 18 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.3762552670951563	[894]	[173,198]	-2	hSpCas9	negative selection	1374471
4445118	4445141	17	+	26627737	RPE1	viability after 18 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	2.3837147739205164	[93]	[99,166]	9	hSpCas9	negative selection	1374477
4446125	4446148	17	-	26627737	RPE1	viability after 18 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.12437603686954718	[591]	[192,153]	0	hSpCas9	negative selection	1374479
4446955	4446978	17	-	26627737	RPE1	viability after 18 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.2677306070562417	[465]	[133,169]	1	hSpCas9	negative selection	1374480
4448198	4448221	17	+	26627737	RPE1	viability after 18 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.20640027881351447	[974]	[243,210]	-1	hSpCas9	negative selection	1374481
4434087	4434110	17	-	26627737	HeLa	viability after 8 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.5712079088692081	[366]	[214,344,152]	5	hSpCas9	negative selection	1456785
4439659	4439682	17	+	26627737	HeLa	viability after 8 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-1.025528099282874	[750]	[220,114,158]	-8	hSpCas9	negative selection	1456786
4445118	4445141	17	+	26627737	HeLa	viability after 8 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	1.3964874169833714	[171]	[151,184,240]	8	hSpCas9	negative selection	1456792
4446125	4446148	17	-	26627737	HeLa	viability after 8 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.3940746748033001	[240]	[142,80,186]	3	hSpCas9	negative selection	1456794
4446955	4446978	17	-	26627737	HeLa	viability after 8 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.5699094293252182	[276]	[249,235,73]	5	hSpCas9	negative selection	1456795
4448198	4448221	17	+	26627737	HeLa	viability after 8 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.2619600112076885	[1171]	[289,543,412]	-3	hSpCas9	negative selection	1456796
4434087	4434110	17	-	26627737	HeLa	viability after 12 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.9550612948477507	[366]	[314,262,307]	7	hSpCas9	negative selection	1539100
4439659	4439682	17	+	26627737	HeLa	viability after 12 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.37640621324408075	[750]	[373,221,126]	-3	hSpCas9	negative selection	1539101
4445118	4445141	17	+	26627737	HeLa	viability after 12 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.6280263312372437	[171]	[89,137,97]	5	hSpCas9	negative selection	1539107
4446125	4446148	17	-	26627737	HeLa	viability after 12 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.7486823609989217	[240]	[148,124,231]	6	hSpCas9	negative selection	1539109
4446955	4446978	17	-	26627737	HeLa	viability after 12 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.1322436770671621	[276]	[172,50,96]	-1	hSpCas9	negative selection	1539110
4448198	4448221	17	+	26627737	HeLa	viability after 12 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.3692889128682104	[1171]	[437,428,253]	-3	hSpCas9	negative selection	1539111
4434087	4434110	17	-	26627737	HeLa	viability after 15 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.23326355002353633	[366]	[59,260,209]	2	hSpCas9	negative selection	1621415
4439659	4439682	17	+	26627737	HeLa	viability after 15 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.5373618444568504	[750]	[212,255,158]	-5	hSpCas9	negative selection	1621416
4445118	4445141	17	+	26627737	HeLa	viability after 15 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	1.4722667374605902	[171]	[116,330,130]	8	hSpCas9	negative selection	1621422
4446125	4446148	17	-	26627737	HeLa	viability after 15 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.6251340678457289	[240]	[121,148,185]	5	hSpCas9	negative selection	1621424
4446955	4446978	17	-	26627737	HeLa	viability after 15 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.6855334078512441	[276]	[131,1,75]	-6	hSpCas9	negative selection	1621425
4448198	4448221	17	+	26627737	HeLa	viability after 15 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.3540424078928781	[1171]	[400,399,313]	-3	hSpCas9	negative selection	1621426
4434087	4434110	17	-	26627737	HeLa	viability after 18 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.2113499381663275	[366]	[35,214,209]	1	hSpCas9	negative selection	1703730
4439659	4439682	17	+	26627737	HeLa	viability after 18 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.521589909501045	[750]	[144,214,158]	-4	hSpCas9	negative selection	1703731
4445118	4445141	17	+	26627737	HeLa	viability after 18 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	1.5307556294224232	[171]	[82,287,130]	8	hSpCas9	negative selection	1703737
4446125	4446148	17	-	26627737	HeLa	viability after 18 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.6055994597223942	[240]	[78,121,185]	5	hSpCas9	negative selection	1703739
4446955	4446978	17	-	26627737	HeLa	viability after 18 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.7316701530802379	[276]	[83,1,75]	-6	hSpCas9	negative selection	1703740
4448198	4448221	17	+	26627737	HeLa	viability after 18 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.2922547547275687	[1171]	[292,340,313]	-3	hSpCas9	negative selection	1703741
4434087	4434110	17	-	26627737	HCT116	viability after 6 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.9136674396910258	[622]	[373,79]	5	hSpCas9	negative selection	1786045
4439659	4439682	17	+	26627737	HCT116	viability after 6 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.31893785248483875	[741]	[224,20]	-2	hSpCas9	negative selection	1786046
4445118	4445141	17	+	26627737	HCT116	viability after 6 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	-1.9202966795732295	[473]	[29,13]	-8	hSpCas9	negative selection	1786052
4446125	4446148	17	-	26627737	HCT116	viability after 6 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.8324032498585028	[702]	[248,167]	4	hSpCas9	negative selection	1786054
4446955	4446978	17	-	26627737	HCT116	viability after 6 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-1.9469835343441466	[193]	[14,3]	-8	hSpCas9	negative selection	1786055
4448198	4448221	17	+	26627737	HCT116	viability after 6 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	1.1935170477492827	[1026]	[162,482]	6	hSpCas9	negative selection	1786056
4434087	4434110	17	-	26627737	HCT116	viability after 8 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.8744554878176376	[229]	[225,326,144]	7	hSpCas9	negative selection	1868360
4439659	4439682	17	+	26627737	HCT116	viability after 8 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.26728006254147696	[548]	[190,311,249]	-3	hSpCas9	negative selection	1868361
4445118	4445141	17	+	26627737	HCT116	viability after 8 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.4691981527544403	[176]	[137,205,61]	5	hSpCas9	negative selection	1868367
4446125	4446148	17	-	26627737	HCT116	viability after 8 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.5157587749599349	[272]	[90,86,136]	-6	hSpCas9	negative selection	1868369
4446955	4446978	17	-	26627737	HCT116	viability after 8 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	1.1626346570060764	[106]	[126,63,203]	8	hSpCas9	negative selection	1868370
4448198	4448221	17	+	26627737	HCT116	viability after 8 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.5764738178672154	[731]	[202,232,372]	-6	hSpCas9	negative selection	1868371
4434087	4434110	17	-	26627737	HCT116	viability after 9 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.7817273494528498	[622]	[514,104]	5	hSpCas9	negative selection	1950675
4439659	4439682	17	+	26627737	HCT116	viability after 9 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.4284044949300666	[741]	[249,65]	-3	hSpCas9	negative selection	1950676
4445118	4445141	17	+	26627737	HCT116	viability after 9 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	-2.0777295857538043	[473]	[53,10]	-8	hSpCas9	negative selection	1950682
4446125	4446148	17	-	26627737	HCT116	viability after 9 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.9823986526893401	[702]	[175,30]	-6	hSpCas9	negative selection	1950684
4446955	4446978	17	-	26627737	HCT116	viability after 9 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	1.177550811256492	[193]	[229,27]	7	hSpCas9	negative selection	1950685
4448198	4448221	17	+	26627737	HCT116	viability after 9 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.2082954429587539	[1026]	[376,126]	-1	hSpCas9	negative selection	1950686
4434087	4434110	17	-	26627737	HCT116	viability after 12 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.116410678167735	[229]	[305,207,266]	8	hSpCas9	negative selection	2032990
4439659	4439682	17	+	26627737	HCT116	viability after 12 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.3294349117283283	[548]	[226,267,194]	-3	hSpCas9	negative selection	2032991
4445118	4445141	17	+	26627737	HCT116	viability after 12 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.761539686029976	[176]	[141,179,152]	6	hSpCas9	negative selection	2032997
4446125	4446148	17	-	26627737	HCT116	viability after 12 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.29407800612969415	[272]	[98,173,80]	-3	hSpCas9	negative selection	2032999
4446955	4446978	17	-	26627737	HCT116	viability after 12 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.9802384586992702	[106]	[116,99,114]	8	hSpCas9	negative selection	2033000
4448198	4448221	17	+	26627737	HCT116	viability after 12 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.45529954201156986	[731]	[216,267,361]	-5	hSpCas9	negative selection	2033001
4434087	4434110	17	-	26627737	HCT116	viability after 15 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.6648617914552322	[229]	[432,388,435]	9	hSpCas9	negative selection	2115305
4439659	4439682	17	+	26627737	HCT116	viability after 15 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.15872326537496173	[548]	[251,340,250]	-2	hSpCas9	negative selection	2115306
4445118	4445141	17	+	26627737	HCT116	viability after 15 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.576576239786502	[176]	[112,178,157]	5	hSpCas9	negative selection	2115312
4446125	4446148	17	-	26627737	HCT116	viability after 15 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.0856575970852326	[272]	[123,139,175]	-1	hSpCas9	negative selection	2115314
4446955	4446978	17	-	26627737	HCT116	viability after 15 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.9472058493904404	[106]	[45,129,169]	7	hSpCas9	negative selection	2115315
4448198	4448221	17	+	26627737	HCT116	viability after 15 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.7613702049663168	[731]	[193,259,282]	-7	hSpCas9	negative selection	2115316
4434087	4434110	17	-	26627737	HCT116	viability after 18 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.1968097503957247	[229]	[109,225,438]	8	hSpCas9	negative selection	2197620
4439659	4439682	17	+	26627737	HCT116	viability after 18 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.4811525296516029	[548]	[210,210,144]	-4	hSpCas9	negative selection	2197621
4445118	4445141	17	+	26627737	HCT116	viability after 18 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.5109597122047721	[176]	[164,76,126]	4	hSpCas9	negative selection	2197627
4446125	4446148	17	-	26627737	HCT116	viability after 18 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-1.3670039006744092	[272]	[40,33,80]	-8	hSpCas9	negative selection	2197629
4446955	4446978	17	-	26627737	HCT116	viability after 18 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.820414632789717	[106]	[63,102,106]	6	hSpCas9	negative selection	2197630
4448198	4448221	17	+	26627737	HCT116	viability after 18 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.22623547489782236	[731]	[385,178,352]	-2	hSpCas9	negative selection	2197631
4441329	4441352	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCACTATATTGCCCAAG	SPNS3	ENSG00000182557	2.346297348584061	[172,220]	[56,398]	7	dCas9-VP64	positive selection	2428378
4435295	4435318	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTGGG	SPNS3	ENSG00000182557	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454613
4471674	4471697	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTCGG	SPNS3	ENSG00000182557	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469946
4433815	4433838	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGTTCCTCCTGACCCCACGG	SPNS3	ENSG00000182557	1.065502375766111	[65,208]	[4,127]	4	dCas9-VP64	positive selection	2473299
4433760	4433783	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTCCGTAGCAGGTCTCAGAGG	SPNS3	ENSG00000182557	0.16367530200192754	[101,128]	[24,31]	0	dCas9-VP64	positive selection	2473300
4433784	4433807	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGACGATGGGGAAATCGCACTGG	SPNS3	ENSG00000182557	2.6699184329798498	[127,87]	[89,216]	8	dCas9-VP64	positive selection	2473301
4441329	4441352	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCACTATATTGCCCAAG	SPNS3	ENSG00000182557	-0.41126224133599143	[350,385]	[99,80]	-4	dCas9-VP64	positive selection	2523633
4435295	4435318	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTGGG	SPNS3	ENSG00000182557	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549868
4471674	4471697	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTCGG	SPNS3	ENSG00000182557	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565201
4433815	4433838	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGTTCCTCCTGACCCCACGG	SPNS3	ENSG00000182557	0.7694788046413007	[63,75]	[23,51]	5	dCas9-VP64	positive selection	2568554
4433760	4433783	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTCCGTAGCAGGTCTCAGAGG	SPNS3	ENSG00000182557	-0.5598258300760469	[120,209]	[29,41]	-5	dCas9-VP64	positive selection	2568555
4433784	4433807	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGACGATGGGGAAATCGCACTGG	SPNS3	ENSG00000182557	0.7457954254046206	[41,48]	[21,26]	5	dCas9-VP64	positive selection	2568556
4448201	4448224	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.8958348067971218	[2,2]	[0,0]	-8	hSpCas9	positive selection	3023442
4448249	4448272	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	0.597002520734065	[4,4]	[3,7]	9	hSpCas9	positive selection	3023443
4446055	4446078	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	-0.024293659196832074	[2,3]	[2,2]	0	hSpCas9	positive selection	3023444
4446158	4446181	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	0.2799305310082224	[4,3]	[3,4]	6	hSpCas9	positive selection	3023445
4448201	4448224	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.22597558759260222	[2,2]	[2,0]	-3	hSpCas9	positive selection	3091300
4448249	4448272	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	0.09083113794139264	[4,4]	[3,2]	1	hSpCas9	positive selection	3091301
4446055	4446078	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	0.2970096269766576	[2,2]	[3,1]	5	hSpCas9	positive selection	3091302
4446158	4446181	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	-0.24842349197986793	[4,4]	[2,1]	-4	hSpCas9	positive selection	3091303
4486489	4486512		+	24336571	A375	resistance to PLX after 7 days	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.00571653993671184	[6,7]	[7,5]	0	hSpCas9	positive selection	3147191
4486446	4486469		-	24336571	A375	resistance to PLX after 7 days	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	-0.23048142402038008	[4,7]	[4,4]	-7	hSpCas9	positive selection	3147192
4486489	4486512		+	24336571	A375	resistance to PLX after 14 days	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	-0.3249994582527308	[7,5]	[1,1]	-4	hSpCas9	positive selection	3204984
4486446	4486469		-	24336571	A375	resistance to PLX after 14 days	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	-0.28877665575091416	[4,4]	[1,1]	-3	hSpCas9	positive selection	3204985
4486489	4486512		+	24336571	A375	viability after 7 days	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	-0.5646743327133078	[11]	[6,7]	-7	hSpCas9	negative selection	3262777
4486446	4486469		-	24336571	A375	viability after 7 days	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	-0.15864991621683944	[6]	[4,7]	-2	hSpCas9	negative selection	3262778
4486489	4486512		+	24336571	A375	viability after 14 days	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	-0.6652711392041006	[11]	[7,5]	-7	hSpCas9	negative selection	3320570
4486446	4486469		-	24336571	A375	viability after 14 days	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	-0.3176902064330346	[6]	[4,4]	-4	hSpCas9	negative selection	3320571
4487864	4487887	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	1.148801754667666	[68,68]	[0,0]	5	hSpCas9	positive selection	3394740
4487811	4487834	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.7463642921684557	[455,455]	[4,4]	3	hSpCas9	positive selection	3394741
4448200	4448223	17	+	26780180	HT29	viability (Avana library 4 designs)	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	1.33387714407186	[]	[]	5	hSpCas9	negative selection	3462068
4448249	4448272	17	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	0.216699325654159	[]	[]	0	hSpCas9	negative selection	3462069
4446054	4446077	17	+	26780180	HT29	viability (Avana library 4 designs)	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	2.57082742347127	[]	[]	8	hSpCas9	negative selection	3462070
4446158	4446181	17	-	26780180	HT29	viability (Avana library 4 designs)	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	0.707190369125498	[]	[]	2	hSpCas9	negative selection	3462071
4446054	4446077	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	2.29900145038626	[]	[]	3	hSpCas9	negative selection	3563420
4448249	4448272	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	4.8015520318234	[]	[]	7	hSpCas9	negative selection	3563421
4446158	4446181	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	3.85668373291017	[]	[]	6	hSpCas9	negative selection	3563422
4448200	4448223	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	3.92465672212442	[]	[]	6	hSpCas9	negative selection	3563423
4439659	4439682	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	3.10000012958805	[]	[]	5	hSpCas9	negative selection	3563424
4434110	4434133	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	3.77753668307648	[]	[]	6	hSpCas9	negative selection	3563425
4446054	4446077	17	+	26780180	A375	viability (Avana lentiGuide)	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	1.31701786830928	[]	[]	1	hSpCas9	negative selection	3672079
4448249	4448272	17	-	26780180	A375	viability (Avana lentiGuide)	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	-0.221457988451889	[]	[]	0	hSpCas9	negative selection	3672080
4446158	4446181	17	-	26780180	A375	viability (Avana lentiGuide)	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	0.357604794203233	[]	[]	0	hSpCas9	negative selection	3672081
4448200	4448223	17	+	26780180	A375	viability (Avana lentiGuide)	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.606030508035767	[]	[]	-1	hSpCas9	negative selection	3672082
4439659	4439682	17	+	26780180	A375	viability (Avana lentiGuide)	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-2.41993243744124	[]	[]	-4	hSpCas9	negative selection	3672083
4434110	4434133	17	-	26780180	A375	viability (Avana lentiGuide)	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.882104842731562	[]	[]	-1	hSpCas9	negative selection	3672084
4446054	4446077	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	-0.08862943330374402	[4]	[4,3]	-1	hSpCas9	positive selection	3780686
4448249	4448272	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	0.15319960788772066	[5]	[6,5]	4	hSpCas9	positive selection	3780687
4446158	4446181	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	0.20884786265516464	[5]	[6,5]	6	hSpCas9	positive selection	3780688
4448200	4448223	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.14494872451289054	[4]	[4,4]	4	hSpCas9	positive selection	3780689
4439659	4439682	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.1618120593916612	[4]	[5,4]	4	hSpCas9	positive selection	3780690
4434110	4434133	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.28602815495237177	[4]	[4,6]	8	hSpCas9	positive selection	3780691
4446054	4446077	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCTCTTCTTCCTGTCCCGGGG	SPNS3	ENSG00000182557	0.12963087539758109	[5]	[4,4]	3	hSpCas9	positive selection	3889293
4448249	4448272	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTCCTGAAGCCTCCCACGG	SPNS3	ENSG00000182557	-0.08082352748368345	[6]	[5,4]	-1	hSpCas9	positive selection	3889294
4446158	4446181	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAGAAGACAGCCAGCACGCGG	SPNS3	ENSG00000182557	0.1295303477780671	[5]	[5,5]	3	hSpCas9	positive selection	3889295
4448200	4448223	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.18664393591652986	[4]	[3,3]	-3	hSpCas9	positive selection	3889296
4439659	4439682	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.410538239149177	[5]	[5,6]	9	hSpCas9	positive selection	3889297
4434110	4434133	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.44322418394171126	[4]	[2,2]	-5	hSpCas9	positive selection	3889298
4486407	4486430	17	+	26780180	A375	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.843409454299487	[]	[]	3	hSpCas9	negative selection	3999043
4486489	4486512	17	+	26780180	A375	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	1.34203683729933	[]	[]	7	hSpCas9	negative selection	3999044
4487811	4487834	17	-	26780180	A375	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.563387042760638	[]	[]	1	hSpCas9	negative selection	3999045
4487864	4487887	17	+	26780180	A375	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.903825459527389	[]	[]	4	hSpCas9	negative selection	3999046
4486407	4486430	17	+	26780180	HT29	viability (GeCKOv2 library)	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.905152573287363	[]	[]	4	hSpCas9	negative selection	4107009
4486489	4486512	17	+	26780180	HT29	viability (GeCKOv2 library)	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	1.22818291966493	[]	[]	6	hSpCas9	negative selection	4107010
4487811	4487834	17	-	26780180	HT29	viability (GeCKOv2 library)	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.935976846098675	[]	[]	4	hSpCas9	negative selection	4107011
4487864	4487887	17	+	26780180	HT29	viability (GeCKOv2 library)	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	1.61156569429529	[]	[]	8	hSpCas9	negative selection	4107012
4486489	4486512	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	-0.7395583626170038	[3]	[0,0]	-9	hSpCas9	positive selection	4173366
4486446	4486469	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	-0.4783858366359129	[2]	[1,0]	-8	hSpCas9	positive selection	4173368
4486489	4486512	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.1940072274875132	[2]	[0,3,1,0]	1	hSpCas9	positive selection	4237388
4486446	4486469	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGCGGAAGCGCTGCAGATAGG	SPNS3	ENSG00000182557	0.3958895761123473	[1]	[0,0,1,0]	3	hSpCas9	positive selection	4237390
4486489	4486512	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.0928315005999783	[3]	[3,2]	2	hSpCas9	positive selection	4300363
4486407	4486430	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.33421176661824	[3]	[2,3]	6	hSpCas9	positive selection	4300365
4487864	4487887	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.29635917442789556	[1]	[0,0]	-6	hSpCas9	positive selection	4364618
4487811	4487834	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.09457097599269321	[3]	[3,1]	-2	hSpCas9	positive selection	4364619
4434085	4434107	17	+	27760321	OCIAML3	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	-0.6475776096686052	[592,516]	[275,276]	-6	hSpCas9	negative selection	4442831
4445079	4445101	17	+	27760321	OCIAML3	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.3742780719844748	[756,616]	[599,813]	4	hSpCas9	negative selection	4442832
4445104	4445126	17	-	27760321	OCIAML3	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.10765536006484422	[320,201]	[196,242]	1	hSpCas9	negative selection	4442833
4446147	4446169	17	+	27760321	OCIAML3	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.12937866399267794	[796,607]	[538,670]	1	hSpCas9	negative selection	4442834
4446189	4446211	17	-	27760321	OCIAML3	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.047482611814544606	[219,199]	[153,189]	0	hSpCas9	negative selection	4442835
4434085	4434107	17	+	27760321	OCIAML2	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.327311576159424	[592,516]	[457,698]	4	hSpCas9	negative selection	4526294
4445079	4445101	17	+	27760321	OCIAML2	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.5030278452353846	[756,616]	[673,927]	7	hSpCas9	negative selection	4526295
4445104	4445126	17	-	27760321	OCIAML2	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.22095129488668075	[320,201]	[256,223]	3	hSpCas9	negative selection	4526296
4446147	4446169	17	+	27760321	OCIAML2	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	-0.12793164391240963	[796,607]	[468,577]	-2	hSpCas9	negative selection	4526297
4446189	4446211	17	-	27760321	OCIAML2	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.1633429051162839	[219,199]	[212,159]	2	hSpCas9	negative selection	4526298
4434085	4434107	17	+	27760321	MV411	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.43374393306097386	[592,516]	[425,594]	3	hSpCas9	negative selection	4609757
4445079	4445101	17	+	27760321	MV411	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.8828077580068848	[756,616]	[730,982]	6	hSpCas9	negative selection	4609758
4445104	4445126	17	-	27760321	MV411	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.013505851522512935	[320,201]	[57,341]	0	hSpCas9	negative selection	4609759
4446147	4446169	17	+	27760321	MV411	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.16549574138552092	[796,607]	[389,704]	1	hSpCas9	negative selection	4609760
4446189	4446211	17	-	27760321	MV411	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.7749971254843862	[219,199]	[0,200]	-5	hSpCas9	negative selection	4609761
4434085	4434107	17	+	27760321	HL60	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.48927118255454677	[592,516]	[681,584]	6	hSpCas9	negative selection	4693220
4445079	4445101	17	+	27760321	HL60	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.4660620797528062	[756,616]	[928,603]	5	hSpCas9	negative selection	4693221
4445104	4445126	17	-	27760321	HL60	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	-0.06822187090172194	[320,201]	[137,266]	-1	hSpCas9	negative selection	4693222
4446147	4446169	17	+	27760321	HL60	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.18055690338147412	[796,607]	[688,598]	2	hSpCas9	negative selection	4693223
4446189	4446211	17	-	27760321	HL60	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.0928697708012256	[219,199]	[168,151]	-1	hSpCas9	negative selection	4693224
4434085	4434107	17	+	27760321	HT1080	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	-0.38115498464606723	[516,403]	[116,166]	-2	hSpCas9	negative selection	4776683
4445079	4445101	17	+	27760321	HT1080	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.4867382179769685	[616,481]	[227,392]	2	hSpCas9	negative selection	4776684
4445104	4445126	17	-	27760321	HT1080	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.10177090527363508	[201,157]	[54,100]	0	hSpCas9	negative selection	4776685
4446147	4446169	17	+	27760321	HT1080	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.6897230731536522	[607,474]	[399,290]	3	hSpCas9	negative selection	4776686
4446189	4446211	17	-	27760321	HT1080	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.035700843371148094	[199,155]	[114,18]	0	hSpCas9	negative selection	4776687
4434085	4434107	17	+	27760321	HT29	viability after 7 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.7501134235452704	[516,403]	[1426,951,678]	9	hSpCas9	negative selection	4860146
4445079	4445101	17	+	27760321	HT29	viability after 7 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.5311234406387996	[616,481]	[1068,1094,907]	7	hSpCas9	negative selection	4860147
4445104	4445126	17	-	27760321	HT29	viability after 7 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.18891129530693973	[201,157]	[182,344,251]	3	hSpCas9	negative selection	4860148
4446147	4446169	17	+	27760321	HT29	viability after 7 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.11771740870133118	[607,474]	[948,465,873]	1	hSpCas9	negative selection	4860149
4446189	4446211	17	-	27760321	HT29	viability after 7 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.3932433296533715	[199,155]	[118,169,223]	-5	hSpCas9	negative selection	4860150
4434085	4434107	17	+	27760321	HT29	viability after 25 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.7241874039448748	[516,403]	[808,818,995]	8	hSpCas9	negative selection	4943609
4445079	4445101	17	+	27760321	HT29	viability after 25 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.5500325254124586	[616,481]	[624,1003,1172]	6	hSpCas9	negative selection	4943610
4445104	4445126	17	-	27760321	HT29	viability after 25 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.5358942653795047	[201,157]	[284,201,420]	6	hSpCas9	negative selection	4943611
4446147	4446169	17	+	27760321	HT29	viability after 25 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	-0.04405050497081742	[607,474]	[515,457,857]	0	hSpCas9	negative selection	4943612
4446189	4446211	17	-	27760321	HT29	viability after 25 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.0519863455783538	[199,155]	[181,238,164]	0	hSpCas9	negative selection	4943613
4434085	4434107	17	+	27760321	HT29	viability after 22 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.6217482641406646	[516,403]	[944,715,792]	7	hSpCas9	negative selection	5027072
4445079	4445101	17	+	27760321	HT29	viability after 22 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.9562565060555442	[616,481]	[1049,1290,1362]	9	hSpCas9	negative selection	5027073
4445104	4445126	17	-	27760321	HT29	viability after 22 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.820311860869684	[201,157]	[412,239,448]	8	hSpCas9	negative selection	5027074
4446147	4446169	17	+	27760321	HT29	viability after 22 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.05351015635188383	[607,474]	[589,676,683]	0	hSpCas9	negative selection	5027075
4446189	4446211	17	-	27760321	HT29	viability after 22 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-0.48843750428577515	[199,155]	[100,218,120]	-4	hSpCas9	negative selection	5027076
4434085	4434107	17	+	27760321	HT29	viability after 19 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	1.1646618488486973	[516,403]	[1011,1147,1356]	9	hSpCas9	negative selection	5110535
4445079	4445101	17	+	27760321	HT29	viability after 19 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.7604751383752723	[616,481]	[766,762,1610]	7	hSpCas9	negative selection	5110536
4445104	4445126	17	-	27760321	HT29	viability after 19 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.8715378657434836	[201,157]	[464,589,94]	8	hSpCas9	negative selection	5110537
4446147	4446169	17	+	27760321	HT29	viability after 19 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	-0.06655107043718544	[607,474]	[629,746,407]	0	hSpCas9	negative selection	5110538
4446189	4446211	17	-	27760321	HT29	viability after 19 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.215517120791327	[199,155]	[53,215,412]	2	hSpCas9	negative selection	5110539
4434085	4434107	17	+	27760321	HT29	viability after 16 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.3802630026414338	[516,403]	[1001,444,601]	4	hSpCas9	negative selection	5193998
4445079	4445101	17	+	27760321	HT29	viability after 16 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.5832649162261861	[616,481]	[930,1005,824]	6	hSpCas9	negative selection	5193999
4445104	4445126	17	-	27760321	HT29	viability after 16 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.5344436176918808	[201,157]	[395,213,276]	6	hSpCas9	negative selection	5194000
4446147	4446169	17	+	27760321	HT29	viability after 16 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.29468653679234547	[607,474]	[833,703,700]	3	hSpCas9	negative selection	5194001
4446189	4446211	17	-	27760321	HT29	viability after 16 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.15238249089347444	[199,155]	[335,135,204]	1	hSpCas9	negative selection	5194002
4434085	4434107	17	+	27760321	HT29	viability after 13 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.2699458568555028	[516,403]	[881,406,642]	3	hSpCas9	negative selection	5277461
4445079	4445101	17	+	27760321	HT29	viability after 13 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.4254707559265206	[616,481]	[714,1001,851]	5	hSpCas9	negative selection	5277462
4445104	4445126	17	-	27760321	HT29	viability after 13 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.06181389514657576	[201,157]	[265,189,198]	0	hSpCas9	negative selection	5277463
4446147	4446169	17	+	27760321	HT29	viability after 13 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.22836266328937405	[607,474]	[831,748,632]	3	hSpCas9	negative selection	5277464
4446189	4446211	17	-	27760321	HT29	viability after 13 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.14837890926860164	[199,155]	[169,122,383]	1	hSpCas9	negative selection	5277465
4434085	4434107	17	+	27760321	HT29	viability after 10 days	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	0.7486860538547493	[516,403]	[989,828,1072]	8	hSpCas9	negative selection	5360924
4445079	4445101	17	+	27760321	HT29	viability after 10 days	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	0.3790136851086233	[616,481]	[941,916,819]	5	hSpCas9	negative selection	5360925
4445104	4445126	17	-	27760321	HT29	viability after 10 days	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.5911022965548502	[201,157]	[284,327,400]	7	hSpCas9	negative selection	5360926
4446147	4446169	17	+	27760321	HT29	viability after 10 days	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.07574646580871358	[607,474]	[928,542,661]	1	hSpCas9	negative selection	5360927
4446189	4446211	17	-	27760321	HT29	viability after 10 days	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	0.17025444934017375	[199,155]	[184,395,174]	2	hSpCas9	negative selection	5360928
4434085	4434107	17	+	27760321	MOLM13	viability	CCCCCGTGGAGGGCCTACGTGG	SPNS3	ENSG00000182557	-0.21667655077150527	[592,516]	[297,243]	-1	hSpCas9	negative selection	5444387
4445079	4445101	17	+	27760321	MOLM13	viability	GGCGACCGACATAGCCGCAAGG	SPNS3	ENSG00000182557	1.2740598678076362	[756,616]	[1542,412]	8	hSpCas9	negative selection	5444388
4445104	4445126	17	-	27760321	MOLM13	viability	AGCAAGATACCGAAGCTCATGG	SPNS3	ENSG00000182557	0.09780992194073246	[320,201]	[303,28]	0	hSpCas9	negative selection	5444389
4446147	4446169	17	+	27760321	MOLM13	viability	GACCAGCGCACCCGCGTGCTGG	SPNS3	ENSG00000182557	0.23745542380303786	[796,607]	[555,384]	1	hSpCas9	negative selection	5444390
4446189	4446211	17	-	27760321	MOLM13	viability	GTGATACCAACCTTCCAACGGG	SPNS3	ENSG00000182557	-2.054515039093528	[219,199]	[14,39]	-8	hSpCas9	negative selection	5444391
4434085	4434108	17	-	27661255	K562	viability	GCCACGTAGGCCCTCCACGGGGG	SPNS3	ENSG00000182557	0.4403394052139815	[187,190]	[193,214]	9	dCas9-KRAB	negative selection	5514023
4434110	4434133	17	-	27661255	K562	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.1869931289605119	[1518,1481]	[1095,1016]	-5	dCas9-KRAB	negative selection	5514024
4434113	4434136	17	-	27661255	K562	viability	GAGGTTGATGTAGCAGAGGACGG	SPNS3	ENSG00000182557	-0.019818496471633806	[1185,1161]	[974,882]	-1	dCas9-KRAB	negative selection	5514025
4434255	4434278	17	-	27661255	K562	viability	GGGCCCAGGAGCAGAAAGATGGG	SPNS3	ENSG00000182557	0.07243743281747134	[957,1181]	[971,829]	2	dCas9-KRAB	negative selection	5514026
4434275	4434298	17	-	27661255	K562	viability	GAGGTGAGAACACCAGAGATGGG	SPNS3	ENSG00000182557	0.056237785795583695	[906,983]	[849,727]	2	dCas9-KRAB	negative selection	5514027
4486489	4486512	17	+	27260156	BXPC3	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.40127247843639635	[841]	[1021,1141,1262,1243]	8	hSpCas9	negative selection	5572823
4486407	4486430	17	+	27260156	BXPC3	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.18320105433768114	[572]	[582,627,748,783]	4	hSpCas9	negative selection	5572825
4487864	4487887	17	+	27260156	BXPC3	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.16203156426242193	[177]	[255,182,197,187]	3	hSpCas9	negative selection	5637078
4487811	4487834	17	-	27260156	BXPC3	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.0932226582208352	[965]	[758,953,1055,1045]	-2	hSpCas9	negative selection	5637079
4486489	4486512	17	+	27260156	A673	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.521405132486749	[841]	[1452,1350,1470,1533]	9	hSpCas9	negative selection	5694074
4486407	4486430	17	+	27260156	A673	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.13228807307545037	[572]	[946,663,633,797]	3	hSpCas9	negative selection	5694076
4487864	4487887	17	+	27260156	A673	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.01079959948925846	[177]	[238,198,226,197]	0	hSpCas9	negative selection	5758329
4487811	4487834	17	-	27260156	A673	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.021436559565268132	[965]	[1211,974,962,1449]	0	hSpCas9	negative selection	5758330
4486489	4486512	17	+	27260156	A375	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.24727297431844963	[841]	[1313,1023,1178,1132]	3	hSpCas9	negative selection	5815325
4486407	4486430	17	+	27260156	A375	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.04972790206534078	[572]	[706,833,877,403]	0	hSpCas9	negative selection	5815327
4487864	4487887	17	+	27260156	A375	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.2370704074112815	[177]	[252,347,123,265]	3	hSpCas9	negative selection	5879580
4487811	4487834	17	-	27260156	A375	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.17856570293267193	[965]	[1217,1437,1295,1183]	2	hSpCas9	negative selection	5879581
4486489	4486512	17	+	27260156	COLO741	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.5066054075116313	[841]	[1484,1560,1531]	8	hSpCas9	negative selection	5936576
4486407	4486430	17	+	27260156	COLO741	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.13269547869933718	[572]	[734,826,835]	3	hSpCas9	negative selection	5936578
4487864	4487887	17	+	27260156	COLO741	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.0016297666064415406	[177]	[300,212,176]	0	hSpCas9	negative selection	6000831
4487811	4487834	17	-	27260156	COLO741	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.042927719078427184	[965]	[1384,1259,1182]	0	hSpCas9	negative selection	6000832
4486489	4486512	17	+	27260156	CAL120	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4419832006782838	[841]	[1884,1087,1366]	6	hSpCas9	negative selection	6057827
4486407	4486430	17	+	27260156	CAL120	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.2882708625600671	[572]	[897,389,511]	-4	hSpCas9	negative selection	6057829
4487864	4487887	17	+	27260156	CAL120	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.449059714848569	[177]	[187,409,291]	6	hSpCas9	negative selection	6122082
4487811	4487834	17	-	27260156	CAL120	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.08182032693129782	[965]	[1703,1010,1167]	1	hSpCas9	negative selection	6122083
4486489	4486512	17	+	27260156	CADOES1	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.18891295105806072	[841]	[914,854,997,798]	3	hSpCas9	negative selection	6179078
4486407	4486430	17	+	27260156	CADOES1	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.08328540434591591	[572]	[584,488,597,586]	1	hSpCas9	negative selection	6179080
4487864	4487887	17	+	27260156	CADOES1	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.01044985265528342	[177]	[183,161,130,180]	0	hSpCas9	negative selection	6243333
4487811	4487834	17	-	27260156	CADOES1	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.027605544087029754	[965]	[962,977,938,777]	0	hSpCas9	negative selection	6243334
4486489	4486512	17	+	27260156	EWS502	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.5177862552903296	[841]	[1338,1270,1179,1305]	8	hSpCas9	negative selection	6300329
4486407	4486430	17	+	27260156	EWS502	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.2335480783325865	[572]	[682,593,762,828]	4	hSpCas9	negative selection	6300331
4487864	4487887	17	+	27260156	EWS502	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.07635594034904791	[177]	[189,144,224,240]	1	hSpCas9	negative selection	6364584
4487811	4487834	17	-	27260156	EWS502	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.1672620681845014	[965]	[883,1230,1262,1250]	3	hSpCas9	negative selection	6364585
4486489	4486512	17	+	27260156	EW8	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.525727649661889	[841]	[1161,1112,819,879]	8	hSpCas9	negative selection	6421580
4486407	4486430	17	+	27260156	EW8	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.2071075829313243	[572]	[468,404,356,391]	-4	hSpCas9	negative selection	6421582
4487864	4487887	17	+	27260156	EW8	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.5417151497259314	[177]	[82,125,59,131]	-7	hSpCas9	negative selection	6485835
4487811	4487834	17	-	27260156	EW8	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.14908318235917484	[965]	[730,735,699,658]	-3	hSpCas9	negative selection	6485836
4486489	4486512	17	+	27260156	CORL105	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.3410857365757274	[841]	[1401,1204,1369,1042]	6	hSpCas9	negative selection	6542831
4486407	4486430	17	+	27260156	CORL105	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.13575136693686046	[572]	[873,624,663,779]	2	hSpCas9	negative selection	6542833
4487864	4487887	17	+	27260156	CORL105	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.2576486869279464	[177]	[167,196,335,306]	5	hSpCas9	negative selection	6607086
4487811	4487834	17	-	27260156	CORL105	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.22236003874643062	[965]	[1279,850,957,799]	-4	hSpCas9	negative selection	6607087
4486489	4486512	17	+	27260156	HS294T	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.6264644047476868	[841]	[495,450,586,471]	7	hSpCas9	negative selection	6664082
4486407	4486430	17	+	27260156	HS294T	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.045454484395730715	[572]	[170,213,268,206]	0	hSpCas9	negative selection	6664084
4487864	4487887	17	+	27260156	HS294T	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.15478909316493294	[177]	[63,53,67,60]	-2	hSpCas9	negative selection	6728337
4487811	4487834	17	-	27260156	HS294T	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.34098223025137187	[965]	[486,493,347,576]	4	hSpCas9	negative selection	6728338
4486489	4486512	17	+	27260156	HCC44	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.40289401110793843	[841]	[1234,1219,1351,1238]	6	hSpCas9	negative selection	6785333
4486407	4486430	17	+	27260156	HCC44	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.097782758549323	[572]	[531,564,590,721]	-2	hSpCas9	negative selection	6785335
4487864	4487887	17	+	27260156	HCC44	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.16152554076763637	[177]	[279,274,203,136]	2	hSpCas9	negative selection	6849588
4487811	4487834	17	-	27260156	HCC44	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.12230515414040688	[965]	[970,1076,1087,875]	-2	hSpCas9	negative selection	6849589
4486489	4486512	17	+	27260156	G402	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.39957712292285574	[841]	[1799,1373,1202,1115]	5	hSpCas9	negative selection	6906584
4486407	4486430	17	+	27260156	G402	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.24936146814492255	[572]	[715,1187,986,452]	3	hSpCas9	negative selection	6906586
4487864	4487887	17	+	27260156	G402	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.8164174292002715	[177]	[52,73,232,119]	-7	hSpCas9	negative selection	6970839
4487811	4487834	17	-	27260156	G402	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.038714900138864694	[965]	[1083,1126,1388,1214]	0	hSpCas9	negative selection	6970840
4486489	4486512	17	+	27260156	L33	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.7559992086653684	[841]	[1353,606,857,1487]	9	hSpCas9	negative selection	7027835
4486407	4486430	17	+	27260156	L33	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.33793862607098857	[572]	[373,219,254,497]	-7	hSpCas9	negative selection	7027837
4487864	4487887	17	+	27260156	L33	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.2933609543652569	[177]	[218,66,158,236]	6	hSpCas9	negative selection	7092090
4487811	4487834	17	-	27260156	L33	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.38840827448845516	[965]	[783,314,390,774]	-7	hSpCas9	negative selection	7092091
4486489	4486512	17	+	27260156	K562	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.30346670580407764	[841]	[1019,824,971,875]	4	hSpCas9	negative selection	7149086
4486407	4486430	17	+	27260156	K562	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.17755651585032578	[572]	[561,838,544,386]	2	hSpCas9	negative selection	7149088
4487864	4487887	17	+	27260156	K562	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.2986108072203142	[177]	[233,229,55,19]	-4	hSpCas9	negative selection	7213341
4487811	4487834	17	-	27260156	K562	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.014296736193926574	[965]	[861,1129,722,708]	0	hSpCas9	negative selection	7213342
4486489	4486512	17	+	27260156	HT29	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.5502237539551615	[841]	[1759,1559,1499,1223]	9	hSpCas9	negative selection	7270337
4486407	4486430	17	+	27260156	HT29	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.08855206131563037	[572]	[813,749,868,553]	1	hSpCas9	negative selection	7270339
4487864	4487887	17	+	27260156	HT29	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.30934030543416235	[177]	[152,111,248,175]	-5	hSpCas9	negative selection	7334592
4487811	4487834	17	-	27260156	HT29	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.10347152030816431	[965]	[1179,1317,1022,893]	-2	hSpCas9	negative selection	7334593
4486489	4486512	17	+	27260156	MHHES1	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4684928003926758	[841]	[1282,1329,1664,1011]	8	hSpCas9	negative selection	7391588
4486407	4486430	17	+	27260156	MHHES1	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.22273620930825966	[572]	[614,662,902,781]	4	hSpCas9	negative selection	7391590
4487864	4487887	17	+	27260156	MHHES1	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.30019511095012374	[177]	[223,133,187,116]	-5	hSpCas9	negative selection	7455843
4487811	4487834	17	-	27260156	MHHES1	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.18101261374118016	[965]	[1360,1015,638,872]	-3	hSpCas9	negative selection	7455844
4486489	4486512	17	+	27260156	MEWO	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.6174175171964611	[841]	[1424,1037,1204]	9	hSpCas9	negative selection	7512839
4486407	4486430	17	+	27260156	MEWO	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.1003104857479653	[572]	[652,443,432]	-2	hSpCas9	negative selection	7512841
4487864	4487887	17	+	27260156	MEWO	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.2598506019009674	[177]	[158,153,107]	-5	hSpCas9	negative selection	7577094
4487811	4487834	17	-	27260156	MEWO	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.01587954683520265	[965]	[1127,840,757]	0	hSpCas9	negative selection	7577095
4486489	4486512	17	+	27260156	LNCAPCLONEFGC	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.20140063462376911	[841]	[790,840,1028,872]	3	hSpCas9	negative selection	7634090
4486407	4486430	17	+	27260156	LNCAPCLONEFGC	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.18323772012720663	[572]	[470,430,458,468]	-3	hSpCas9	negative selection	7634092
4487864	4487887	17	+	27260156	LNCAPCLONEFGC	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.13781318936877485	[177]	[152,68,165,205]	-2	hSpCas9	negative selection	7698345
4487811	4487834	17	-	27260156	LNCAPCLONEFGC	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.22715039347413435	[965]	[687,1155,1069,1186]	3	hSpCas9	negative selection	7698346
4486489	4486512	17	+	27260156	PANC0327	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.6465009995564086	[841]	[1481,810,818,1641]	8	hSpCas9	negative selection	7755341
4486407	4486430	17	+	27260156	PANC0327	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.04350130792978896	[572]	[621,360,434,708]	0	hSpCas9	negative selection	7755343
4487864	4487887	17	+	27260156	PANC0327	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.05978644197457017	[177]	[330,53,106,141]	-1	hSpCas9	negative selection	7819596
4487811	4487834	17	-	27260156	PANC0327	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.19925909613490966	[965]	[796,928,663,579]	-3	hSpCas9	negative selection	7819597
4486489	4486512	17	+	27260156	NCIH2009	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.6600184564257385	[841]	[2206,1758,1677]	8	hSpCas9	negative selection	7876592
4486407	4486430	17	+	27260156	NCIH2009	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.11583542282989301	[572]	[1240,583,854]	1	hSpCas9	negative selection	7876594
4487864	4487887	17	+	27260156	NCIH2009	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.15443190652737604	[177]	[500,233,139]	2	hSpCas9	negative selection	7940847
4487811	4487834	17	-	27260156	NCIH2009	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.14856072050956204	[965]	[1973,1008,820]	-2	hSpCas9	negative selection	7940848
4486489	4486512	17	+	27260156	NCIH1373	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.5530627034648714	[841]	[1759,809,1991,277]	5	hSpCas9	negative selection	7997843
4486407	4486430	17	+	27260156	NCIH1373	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.275590947362373	[572]	[920,616,927,175]	2	hSpCas9	negative selection	7997845
4487864	4487887	17	+	27260156	NCIH1373	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.07508569426142575	[177]	[264,206,209,42]	0	hSpCas9	negative selection	8062098
4487811	4487834	17	-	27260156	NCIH1373	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.10369949402363488	[965]	[1745,831,1342,217]	1	hSpCas9	negative selection	8062099
4486489	4486512	17	+	27260156	PATU8902	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.7200758809708383	[841]	[1250,2374,1372,2994]	7	hSpCas9	negative selection	8119094
4486407	4486430	17	+	27260156	PATU8902	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.2624710378201369	[572]	[1402,870,637,989]	2	hSpCas9	negative selection	8119096
4487864	4487887	17	+	27260156	PATU8902	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.22602941020859113	[177]	[238,246,202,151]	-2	hSpCas9	negative selection	8183349
4487811	4487834	17	-	27260156	PATU8902	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.3813562180552146	[965]	[1629,1763,1414,2346]	4	hSpCas9	negative selection	8183350
4486489	4486512	17	+	27260156	PANC1	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	-0.006621055161782685	[841]	[850,966,622,508]	0	hSpCas9	negative selection	8240345
4486407	4486430	17	+	27260156	PANC1	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.015398830042132328	[572]	[335,644,477,511]	0	hSpCas9	negative selection	8240347
4487864	4487887	17	+	27260156	PANC1	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.14303173702183924	[177]	[82,193,153,133]	-2	hSpCas9	negative selection	8304600
4487811	4487834	17	-	27260156	PANC1	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.07875478890001164	[965]	[761,986,939,526]	-1	hSpCas9	negative selection	8304601
4486489	4486512	17	+	27260156	PANC0813	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4785706397437206	[841]	[1338,1174,1447,1535]	7	hSpCas9	negative selection	8361596
4486407	4486430	17	+	27260156	PANC0813	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.059517682084233026	[572]	[721,771,731,586]	1	hSpCas9	negative selection	8361598
4487864	4487887	17	+	27260156	PANC0813	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.2895045663248159	[177]	[196,109,197,180]	-4	hSpCas9	negative selection	8425851
4487811	4487834	17	-	27260156	PANC0813	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.1320372650261401	[965]	[1303,1157,766,939]	-2	hSpCas9	negative selection	8425852
4486489	4486512	17	+	27260156	RDES	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.566528438689317	[841]	[1141,1248,1632,1816]	8	hSpCas9	negative selection	8482847
4486407	4486430	17	+	27260156	RDES	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.0709184433563646	[572]	[534,725,673,869]	1	hSpCas9	negative selection	8482849
4487864	4487887	17	+	27260156	RDES	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.334928159691662	[177]	[202,340,261,215]	5	hSpCas9	negative selection	8547102
4487811	4487834	17	-	27260156	RDES	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.2606694861526839	[965]	[1030,1201,1693,1469]	4	hSpCas9	negative selection	8547103
4486489	4486512	17	+	27260156	PC3	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4909346793592806	[841]	[899,1093,1748,1186]	8	hSpCas9	negative selection	8604098
4486407	4486430	17	+	27260156	PC3	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.09001600068806243	[572]	[354,573,1124,637]	2	hSpCas9	negative selection	8604100
4487864	4487887	17	+	27260156	PC3	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.1570141656825872	[177]	[117,247,276,191]	3	hSpCas9	negative selection	8668353
4487811	4487834	17	-	27260156	PC3	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.18250525549996288	[965]	[592,904,1380,733]	-4	hSpCas9	negative selection	8668354
4486489	4486512	17	+	27260156	PATU8988T	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4342608987195711	[841]	[1407,964,1015,987]	7	hSpCas9	negative selection	8725349
4486407	4486430	17	+	27260156	PATU8988T	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.1802742583108202	[572]	[368,500,479,615]	-3	hSpCas9	negative selection	8725351
4487864	4487887	17	+	27260156	PATU8988T	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.5654437317298514	[177]	[218,251,255,293]	8	hSpCas9	negative selection	8789604
4487811	4487834	17	-	27260156	PATU8988T	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.11679406647218216	[965]	[780,981,801,892]	-2	hSpCas9	negative selection	8789605
4486489	4486512	17	+	27260156	T47D	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.49172785733431734	[841]	[1242,1220,1400,1673]	8	hSpCas9	negative selection	8846600
4486407	4486430	17	+	27260156	T47D	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.01939314774305606	[572]	[706,660,657,681]	0	hSpCas9	negative selection	8846602
4487864	4487887	17	+	27260156	T47D	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.11594070701648795	[177]	[224,147,205,189]	-3	hSpCas9	negative selection	8910855
4487811	4487834	17	-	27260156	T47D	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.02101001693659943	[965]	[1203,983,1163,1093]	0	hSpCas9	negative selection	8910856
4486489	4486512	17	+	27260156	SU8686	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.7179236446004047	[841]	[1197,1388,1299,1656]	9	hSpCas9	negative selection	8967851
4486407	4486430	17	+	27260156	SU8686	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.04044132188458255	[572]	[504,542,629,686]	0	hSpCas9	negative selection	8967853
4487864	4487887	17	+	27260156	SU8686	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.2472712095432552	[177]	[178,126,141,143]	-4	hSpCas9	negative selection	9032106
4487811	4487834	17	-	27260156	SU8686	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.03890728339595473	[965]	[792,886,928,1173]	0	hSpCas9	negative selection	9032107
4486489	4486512	17	+	27260156	SKES1	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.3177219233142512	[841]	[1160,1198,914,948]	6	hSpCas9	negative selection	9089102
4486407	4486430	17	+	27260156	SKES1	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.03404944955415784	[572]	[788,405,657,497]	0	hSpCas9	negative selection	9089104
4487864	4487887	17	+	27260156	SKES1	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.44466364797761493	[177]	[306,206,334,131]	8	hSpCas9	negative selection	9153357
4487811	4487834	17	-	27260156	SKES1	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.03830039147049136	[965]	[955,1035,816,948]	-1	hSpCas9	negative selection	9153358
4486489	4486512	17	+	27260156	TOV112D	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.4963575714757287	[841]	[1245,1370,1149,1042]	8	hSpCas9	negative selection	9210353
4486407	4486430	17	+	27260156	TOV112D	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.024953348567388622	[572]	[631,1105,428,307]	0	hSpCas9	negative selection	9210355
4487864	4487887	17	+	27260156	TOV112D	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.19635850480870354	[177]	[213,164,154,96]	-4	hSpCas9	negative selection	9274608
4487811	4487834	17	-	27260156	TOV112D	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.16492395967460993	[965]	[907,1469,887,1148]	3	hSpCas9	negative selection	9274609
4486489	4486512	17	+	27260156	TC71	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.3443681210271716	[841]	[1282,967,985,1361]	7	hSpCas9	negative selection	9331604
4486407	4486430	17	+	27260156	TC71	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	0.04098534810784965	[572]	[685,585,619,634]	1	hSpCas9	negative selection	9331606
4487864	4487887	17	+	27260156	TC71	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	0.17002363227255013	[177]	[150,198,297,208]	4	hSpCas9	negative selection	9395859
4487811	4487834	17	-	27260156	TC71	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	-0.08324062851818037	[965]	[800,1066,992,1056]	-2	hSpCas9	negative selection	9395860
4486489	4486512	17	+	27260156	TC32	viability	CTGCGCCTTTGTCATCGCCCTGG	SPNS3	ENSG00000182557	0.5588687982628191	[841]	[1078,1006,1541,1093]	8	hSpCas9	negative selection	9452855
4486407	4486430	17	+	27260156	TC32	viability	CGCAGATCTCTAGTGTCCTGCGG	SPNS3	ENSG00000182557	-0.034131462868684015	[572]	[508,396,609,626]	0	hSpCas9	negative selection	9452857
4487864	4487887	17	+	27260156	TC32	viability	GGGCGCTGGCGCCTCTACAGAGG	SPNS3	ENSG00000182557	-0.47222525375049496	[177]	[85,115,134,147]	-7	hSpCas9	negative selection	9517110
4487811	4487834	17	-	27260156	TC32	viability	CTGTCCACATCATTGCTGTCTGG	SPNS3	ENSG00000182557	0.08389081139161458	[965]	[801,590,1156,1468]	1	hSpCas9	negative selection	9517111
4434087	4434110	17	-	27869803	HPAFII	viability after 27 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.909088198460007	[206]	[175,227,NaN]	7	hSpCas9	negative selection	9561283
4439659	4439682	17	+	27869803	HPAFII	viability after 27 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.013069740524915163	[367]	[218,168,NaN]	0	hSpCas9	negative selection	9561284
4445118	4445141	17	+	27869803	HPAFII	viability after 27 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.041949230172262375	[172]	[79,104,NaN]	0	hSpCas9	negative selection	9561290
4446125	4446148	17	-	27869803	HPAFII	viability after 27 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	1.2821674880770213	[107]	[220,68,NaN]	9	hSpCas9	negative selection	9561292
4446955	4446978	17	-	27869803	HPAFII	viability after 27 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.005040416326232533	[134]	[79,62,NaN]	0	hSpCas9	negative selection	9561293
4448198	4448221	17	+	27869803	HPAFII	viability after 27 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.6327154087148428	[484]	[164,163,NaN]	-4	hSpCas9	negative selection	9561294
4434087	4434110	17	-	27869803	HPAFII	viability after 15 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.5957889707819126	[206]	[342,331,NaN]	6	hSpCas9	negative selection	9643732
4439659	4439682	17	+	27869803	HPAFII	viability after 15 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.27237194738214787	[367]	[406,277,NaN]	-3	hSpCas9	negative selection	9643733
4445118	4445141	17	+	27869803	HPAFII	viability after 15 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.6071541457064977	[172]	[445,181,NaN]	7	hSpCas9	negative selection	9643739
4446125	4446148	17	-	27869803	HPAFII	viability after 15 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	1.2896103047449834	[107]	[448,180,NaN]	9	hSpCas9	negative selection	9643741
4446955	4446978	17	-	27869803	HPAFII	viability after 15 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.4074347471395486	[134]	[205,183,NaN]	5	hSpCas9	negative selection	9643742
4448198	4448221	17	+	27869803	HPAFII	viability after 15 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.2730711203124335	[484]	[521,374,NaN]	-3	hSpCas9	negative selection	9643743
4434087	4434110	17	-	27869803	ASPC1	viability after 36 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.3883240085463133	[624]	[419,404,802]	9	hSpCas9	negative selection	9726181
4439659	4439682	17	+	27869803	ASPC1	viability after 36 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.40042144389217826	[966]	[190,925,237]	4	hSpCas9	negative selection	9726182
4445118	4445141	17	+	27869803	ASPC1	viability after 36 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.5037477307805704	[337]	[219,70,204]	5	hSpCas9	negative selection	9726188
4446125	4446148	17	-	27869803	ASPC1	viability after 36 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.021332698205001832	[415]	[91,96,213]	0	hSpCas9	negative selection	9726190
4446955	4446978	17	-	27869803	ASPC1	viability after 36 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.4303770554172317	[386]	[93,71,125]	-4	hSpCas9	negative selection	9726191
4448198	4448221	17	+	27869803	ASPC1	viability after 36 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.048043962528671935	[1197]	[572,657,149]	0	hSpCas9	negative selection	9726192
4434087	4434110	17	-	27869803	PATU8988S	viability after 35 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.761585753436549	[577]	[464,323,NaN]	7	hSpCas9	negative selection	9808630
4439659	4439682	17	+	27869803	PATU8988S	viability after 35 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.11468807206749754	[716]	[165,459,NaN]	1	hSpCas9	negative selection	9808631
4445118	4445141	17	+	27869803	PATU8988S	viability after 35 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.48416875753213495	[371]	[239,178,NaN]	5	hSpCas9	negative selection	9808637
4446125	4446148	17	-	27869803	PATU8988S	viability after 35 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.12779851727209757	[390]	[198,144,NaN]	1	hSpCas9	negative selection	9808639
4446955	4446978	17	-	27869803	PATU8988S	viability after 35 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.6722758012882989	[355]	[77,101,NaN]	-6	hSpCas9	negative selection	9808640
4448198	4448221	17	+	27869803	PATU8988S	viability after 35 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.5823780865769652	[964]	[288,229,NaN]	-5	hSpCas9	negative selection	9808641
4434087	4434110	17	-	27869803	PATU8988S	viability after 31 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	0.978738369376356	[577]	[473,428,NaN]	9	hSpCas9	negative selection	9891079
4439659	4439682	17	+	27869803	PATU8988S	viability after 31 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.08937226360843292	[716]	[158,488,NaN]	1	hSpCas9	negative selection	9891080
4445118	4445141	17	+	27869803	PATU8988S	viability after 31 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.541665694325247	[371]	[218,211,NaN]	6	hSpCas9	negative selection	9891086
4446125	4446148	17	-	27869803	PATU8988S	viability after 31 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	-0.09607809186395166	[390]	[67,244,NaN]	-1	hSpCas9	negative selection	9891088
4446955	4446978	17	-	27869803	PATU8988S	viability after 31 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	-0.3246357601192802	[355]	[60,179,NaN]	-4	hSpCas9	negative selection	9891089
4448198	4448221	17	+	27869803	PATU8988S	viability after 31 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.4156208410707781	[964]	[258,325,NaN]	-5	hSpCas9	negative selection	9891090
4434087	4434110	17	-	27869803	HPAFII	viability after 35 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.196347290434007	[206]	[51,451,NaN]	7	hSpCas9	negative selection	9973528
4439659	4439682	17	+	27869803	HPAFII	viability after 35 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.2853011509557658	[367]	[298,145,NaN]	1	hSpCas9	negative selection	9973529
4445118	4445141	17	+	27869803	HPAFII	viability after 35 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	-0.3651606939437424	[172]	[59,76,NaN]	-2	hSpCas9	negative selection	9973535
4446125	4446148	17	-	27869803	HPAFII	viability after 35 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.15569309379975493	[107]	[106,8,NaN]	1	hSpCas9	negative selection	9973537
4446955	4446978	17	-	27869803	HPAFII	viability after 35 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.32841793824254384	[134]	[66,106,NaN]	2	hSpCas9	negative selection	9973538
4448198	4448221	17	+	27869803	HPAFII	viability after 35 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	0.1347381600267724	[484]	[222,321,NaN]	0	hSpCas9	negative selection	9973539
4434087	4434110	17	-	27869803	HPAFII	viability after 31 days	CAGCCACGTAGGCCCTCCACGGG	SPNS3	ENSG00000182557	1.2113849126424614	[206]	[56,499,NaN]	8	hSpCas9	negative selection	10055977
4439659	4439682	17	+	27869803	HPAFII	viability after 31 days	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.17368576383933976	[367]	[309,148,NaN]	1	hSpCas9	negative selection	10055978
4445118	4445141	17	+	27869803	HPAFII	viability after 31 days	ATCTTGCTGTGGTCAGGAGCTGG	SPNS3	ENSG00000182557	0.22946188716164745	[172]	[42,190,NaN]	1	hSpCas9	negative selection	10055984
4446125	4446148	17	-	27869803	HPAFII	viability after 31 days	CCCTCACGAAGAGGTCGCCCAGG	SPNS3	ENSG00000182557	0.044267982173876064	[107]	[95,25,NaN]	0	hSpCas9	negative selection	10055986
4446955	4446978	17	-	27869803	HPAFII	viability after 31 days	GGAAGCTGGACTCACTCGGAGGG	SPNS3	ENSG00000182557	0.5627139166106517	[134]	[53,174,NaN]	4	hSpCas9	negative selection	10055987
4448198	4448221	17	+	27869803	HPAFII	viability after 31 days	TGCTGGTTCCAGACCCACCCCGG	SPNS3	ENSG00000182557	-0.3140120978339438	[484]	[161,280,NaN]	-2	hSpCas9	negative selection	10055988
4448174	4448197	17	-	28162770	P31FUJ	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.1463900959177431	[162]	[211]	1	hSpCas9	negative selection	10242201
4434110	4434133	17	-	28162770	P31FUJ	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.6792186304260825	[261]	[492]	7	hSpCas9	negative selection	10242202
4439659	4439682	17	+	28162770	P31FUJ	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.36269096379894694	[181]	[274]	4	hSpCas9	negative selection	10242203
4446118	4446141	17	-	28162770	P31FUJ	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.054479747666092426	[176]	[215]	0	hSpCas9	negative selection	10242204
4448200	4448223	17	+	28162770	P31FUJ	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.029391224980044317	[285]	[342]	0	hSpCas9	negative selection	10242205
4448219	4448242	17	+	28162770	P31FUJ	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.6359532623073688	[91]	[167]	7	hSpCas9	negative selection	10242206
4453151	4453174	17	-	28162770	P31FUJ	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.5120469888276608	[218]	[366]	6	hSpCas9	negative selection	10242207
4434053	4434076	17	-	28162770	P31FUJ	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.4999062745572196	[141]	[58]	-7	hSpCas9	negative selection	10242208
4448174	4448197	17	-	28162770	TF1	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10411567
4434110	4434133	17	-	28162770	TF1	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10411568
4439659	4439682	17	+	28162770	TF1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	NaN	[NaN]	[202]	1	hSpCas9	negative selection	10411569
4446118	4446141	17	-	28162770	TF1	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10411570
4448200	4448223	17	+	28162770	TF1	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10411571
4448219	4448242	17	+	28162770	TF1	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10411572
4453151	4453174	17	-	28162770	TF1	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10411573
4434053	4434076	17	-	28162770	TF1	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10411574
4448174	4448197	17	-	28162770	SKM1	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.2895066171949848	[55]	[80]	-2	hSpCas9	negative selection	10580933
4434110	4434133	17	-	28162770	SKM1	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.47345418550416585	[98]	[242]	4	hSpCas9	negative selection	10580934
4439659	4439682	17	+	28162770	SKM1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.6090481192454693	[55]	[150]	6	hSpCas9	negative selection	10580935
4446118	4446141	17	-	28162770	SKM1	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.2731555350183346	[43]	[93]	2	hSpCas9	negative selection	10580936
4448200	4448223	17	+	28162770	SKM1	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.14533211305767246	[66]	[130]	1	hSpCas9	negative selection	10580937
4448219	4448242	17	+	28162770	SKM1	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.1779983019779947	[20]	[41]	1	hSpCas9	negative selection	10580938
4453151	4453174	17	-	28162770	SKM1	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.23046572187212996	[53]	[111]	2	hSpCas9	negative selection	10580939
4434053	4434076	17	-	28162770	SKM1	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-0.6776117886868307	[18]	[20]	-5	hSpCas9	negative selection	10580940
4448174	4448197	17	-	28162770	SKM1	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.2895066171949848	[55]	[80]	-2	hSpCas9	negative selection	10750299
4434110	4434133	17	-	28162770	SKM1	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.47345418550416585	[98]	[242]	4	hSpCas9	negative selection	10750300
4439659	4439682	17	+	28162770	SKM1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.6090481192454693	[55]	[150]	6	hSpCas9	negative selection	10750301
4446118	4446141	17	-	28162770	SKM1	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.2731555350183346	[43]	[93]	2	hSpCas9	negative selection	10750302
4448200	4448223	17	+	28162770	SKM1	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.14533211305767246	[66]	[130]	1	hSpCas9	negative selection	10750303
4448219	4448242	17	+	28162770	SKM1	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.1779983019779947	[20]	[41]	1	hSpCas9	negative selection	10750304
4453151	4453174	17	-	28162770	SKM1	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.23046572187212996	[53]	[111]	2	hSpCas9	negative selection	10750305
4434053	4434076	17	-	28162770	SKM1	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-0.6776117886868307	[18]	[20]	-5	hSpCas9	negative selection	10750306
4448174	4448197	17	-	28162770	PL21	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.5057658970475821	[88]	[54]	4	hSpCas9	negative selection	10919665
4434110	4434133	17	-	28162770	PL21	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.5827622638437451	[350]	[101]	-4	hSpCas9	negative selection	10919666
4439659	4439682	17	+	28162770	PL21	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.21769798587362477	[244]	[123]	2	hSpCas9	negative selection	10919667
4446118	4446141	17	-	28162770	PL21	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.3272515323926594	[151]	[82]	3	hSpCas9	negative selection	10919668
4448200	4448223	17	+	28162770	PL21	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.8512923949049429	[283]	[222]	7	hSpCas9	negative selection	10919669
4448219	4448242	17	+	28162770	PL21	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	-1.2079451241477566	[68]	[12]	-7	hSpCas9	negative selection	10919670
4453151	4453174	17	-	28162770	PL21	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-1.3117594240421124	[153]	[26]	-7	hSpCas9	negative selection	10919671
4434053	4434076	17	-	28162770	PL21	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-4.929143402455647	[69]	[0]	-9	hSpCas9	negative selection	10919672
4448174	4448197	17	-	28162770	P31FUJ	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.1463900959177431	[162]	[211]	1	hSpCas9	negative selection	11089031
4434110	4434133	17	-	28162770	P31FUJ	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.6792186304260825	[261]	[492]	7	hSpCas9	negative selection	11089032
4439659	4439682	17	+	28162770	P31FUJ	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.36269096379894694	[181]	[274]	4	hSpCas9	negative selection	11089033
4446118	4446141	17	-	28162770	P31FUJ	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.054479747666092426	[176]	[215]	0	hSpCas9	negative selection	11089034
4448200	4448223	17	+	28162770	P31FUJ	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.029391224980044317	[285]	[342]	0	hSpCas9	negative selection	11089035
4448219	4448242	17	+	28162770	P31FUJ	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.6359532623073688	[91]	[167]	7	hSpCas9	negative selection	11089036
4453151	4453174	17	-	28162770	P31FUJ	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.5120469888276608	[218]	[366]	6	hSpCas9	negative selection	11089037
4434053	4434076	17	-	28162770	P31FUJ	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.4999062745572196	[141]	[58]	-7	hSpCas9	negative selection	11089038
4448174	4448197	17	-	28162770	OCIAML5	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.54428636514992	[67]	[178]	5	hSpCas9	negative selection	11258397
4434110	4434133	17	-	28162770	OCIAML5	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.4288551401394529	[175]	[235]	-3	hSpCas9	negative selection	11258398
4439659	4439682	17	+	28162770	OCIAML5	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.15839781070034084	[114]	[185]	-1	hSpCas9	negative selection	11258399
4446118	4446141	17	-	28162770	OCIAML5	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	-0.7016497283108986	[90]	[100]	-4	hSpCas9	negative selection	11258400
4448200	4448223	17	+	28162770	OCIAML5	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.23539521041550265	[134]	[206]	-2	hSpCas9	negative selection	11258401
4448219	4448242	17	+	28162770	OCIAML5	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.45355971169426496	[88]	[219]	4	hSpCas9	negative selection	11258402
4453151	4453174	17	-	28162770	OCIAML5	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-0.17964122889250148	[127]	[203]	-1	hSpCas9	negative selection	11258403
4434053	4434076	17	-	28162770	OCIAML5	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.9875815415204783	[144]	[65]	-8	hSpCas9	negative selection	11258404
4448174	4448197	17	-	28162770	EOL1	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.5326591819522488	[161]	[58]	-4	hSpCas9	negative selection	11427763
4434110	4434133	17	-	28162770	EOL1	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.05498812586974977	[559]	[283]	0	hSpCas9	negative selection	11427764
4439659	4439682	17	+	28162770	EOL1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.8697509976616233	[384]	[110]	-6	hSpCas9	negative selection	11427765
4446118	4446141	17	-	28162770	EOL1	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	1.2734777235077075	[306]	[390]	9	hSpCas9	negative selection	11427766
4448200	4448223	17	+	28162770	EOL1	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	-0.6547459790639296	[507]	[169]	-5	hSpCas9	negative selection	11427767
4448219	4448242	17	+	28162770	EOL1	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.13971586613906983	[142]	[82]	1	hSpCas9	negative selection	11427768
4453151	4453174	17	-	28162770	EOL1	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.09701496757530018	[251]	[141]	0	hSpCas9	negative selection	11427769
4434053	4434076	17	-	28162770	EOL1	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-0.16291506967980496	[101]	[47]	-1	hSpCas9	negative selection	11427770
4448174	4448197	17	-	28162770	MOLM13	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.4304146761259161	[155]	[151]	3	hSpCas9	negative selection	11597129
4434110	4434133	17	-	28162770	MOLM13	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.9302325956017794	[449]	[619]	7	hSpCas9	negative selection	11597130
4439659	4439682	17	+	28162770	MOLM13	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	1.0156532643114855	[274]	[401]	7	hSpCas9	negative selection	11597131
4446118	4446141	17	-	28162770	MOLM13	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	-0.5663263337933343	[255]	[124]	-3	hSpCas9	negative selection	11597132
4448200	4448223	17	+	28162770	MOLM13	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.6633147552807572	[323]	[370]	5	hSpCas9	negative selection	11597133
4448219	4448242	17	+	28162770	MOLM13	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	-1.4463807444295376	[146]	[38]	-6	hSpCas9	negative selection	11597134
4453151	4453174	17	-	28162770	MOLM13	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.06011988272977432	[263]	[198]	0	hSpCas9	negative selection	11597135
4434053	4434076	17	-	28162770	MOLM13	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-0.8622592201477519	[87]	[34]	-5	hSpCas9	negative selection	11597136
4448174	4448197	17	-	28162770	HEL	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.8871575596668039	[129]	[153]	7	hSpCas9	negative selection	11766495
4434110	4434133	17	-	28162770	HEL	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.15736635097785912	[396]	[227]	-1	hSpCas9	negative selection	11766496
4439659	4439682	17	+	28162770	HEL	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.4728138305580446	[260]	[231]	4	hSpCas9	negative selection	11766497
4446118	4446141	17	-	28162770	HEL	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.9037427026067799	[236]	[283]	7	hSpCas9	negative selection	11766498
4448200	4448223	17	+	28162770	HEL	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.47102721108403034	[302]	[268]	4	hSpCas9	negative selection	11766499
4448219	4448242	17	+	28162770	HEL	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	-0.0460594797053393	[107]	[66]	0	hSpCas9	negative selection	11766500
4453151	4453174	17	-	28162770	HEL	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-0.3779206385657359	[210]	[103]	-3	hSpCas9	negative selection	11766501
4434053	4434076	17	-	28162770	HEL	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-2.420270965525443	[116]	[13]	-8	hSpCas9	negative selection	11766502
4448174	4448197	17	-	28162770	MV411	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-1.2186475540864612	[162]	[58]	-7	hSpCas9	negative selection	11935861
4434110	4434133	17	-	28162770	MV411	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.11040084309932696	[308]	[280]	0	hSpCas9	negative selection	11935862
4439659	4439682	17	+	28162770	MV411	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	-0.7855775064451875	[220]	[107]	-5	hSpCas9	negative selection	11935863
4446118	4446141	17	-	28162770	MV411	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.884867471398067	[188]	[293]	7	hSpCas9	negative selection	11935864
4448200	4448223	17	+	28162770	MV411	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.48748863861572994	[231]	[273]	4	hSpCas9	negative selection	11935865
4448219	4448242	17	+	28162770	MV411	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	1.161280907033061	[68]	[129]	8	hSpCas9	negative selection	11935866
4453151	4453174	17	-	28162770	MV411	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.08644567411047076	[160]	[143]	0	hSpCas9	negative selection	11935867
4434053	4434076	17	-	28162770	MV411	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	0.3883000866226247	[38]	[42]	3	hSpCas9	negative selection	11935868
4448174	4448197	17	-	28162770	MONOMAC1	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	1.0718981602139246	[60]	[146]	8	hSpCas9	negative selection	12105227
4434110	4434133	17	-	28162770	MONOMAC1	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	0.7183007558710623	[192]	[363]	7	hSpCas9	negative selection	12105228
4439659	4439682	17	+	28162770	MONOMAC1	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.5883691021644055	[122]	[211]	6	hSpCas9	negative selection	12105229
4446118	4446141	17	-	28162770	MONOMAC1	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.4285676381589486	[104]	[161]	4	hSpCas9	negative selection	12105230
4448200	4448223	17	+	28162770	MONOMAC1	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.3990662112668028	[171]	[259]	4	hSpCas9	negative selection	12105231
4448219	4448242	17	+	28162770	MONOMAC1	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	0.9848014759262596	[66]	[151]	8	hSpCas9	negative selection	12105232
4453151	4453174	17	-	28162770	MONOMAC1	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-0.3710662468346026	[87]	[77]	-3	hSpCas9	negative selection	12105233
4434053	4434076	17	-	28162770	MONOMAC1	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	0.22478981788192898	[52]	[70]	2	hSpCas9	negative selection	12105234
4448174	4448197	17	-	28162770	OCIAML2	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	-0.8383616097426485	[19]	[61]	-5	hSpCas9	negative selection	12274593
4434110	4434133	17	-	28162770	OCIAML2	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.22904383867240233	[47]	[226]	-2	hSpCas9	negative selection	12274594
4439659	4439682	17	+	28162770	OCIAML2	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.2645753110596076	[40]	[272]	2	hSpCas9	negative selection	12274595
4446118	4446141	17	-	28162770	OCIAML2	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	0.24421295802590487	[22]	[150]	2	hSpCas9	negative selection	12274596
4448200	4448223	17	+	28162770	OCIAML2	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.49175588295806094	[33]	[264]	5	hSpCas9	negative selection	12274597
4448219	4448242	17	+	28162770	OCIAML2	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	-0.511271809739507	[17]	[69]	-4	hSpCas9	negative selection	12274598
4453151	4453174	17	-	28162770	OCIAML2	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	-0.2900575796003404	[29]	[135]	-2	hSpCas9	negative selection	12274599
4434053	4434076	17	-	28162770	OCIAML2	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-2.392627313240888	[17]	[18]	-8	hSpCas9	negative selection	12274600
4448174	4448197	17	-	28162770	OCIAML3	viability	GATAAGCAGGATCAAGGCCACGG	SPNS3	ENSG00000182557	0.3930533039683387	[27]	[110]	3	hSpCas9	negative selection	12443959
4434110	4434133	17	-	28162770	OCIAML3	viability	GTTGATGTAGCAGAGGACGGCGG	SPNS3	ENSG00000182557	-0.9065978706321891	[76]	[123]	-6	hSpCas9	negative selection	12443960
4439659	4439682	17	+	28162770	OCIAML3	viability	AGTGCTGCTGGATATACAGGAGG	SPNS3	ENSG00000182557	0.14033248443521973	[54]	[182]	1	hSpCas9	negative selection	12443961
4446118	4446141	17	-	28162770	OCIAML3	viability	GAAGAGGTCGCCCAGGACGGTGG	SPNS3	ENSG00000182557	1.3586866448974804	[30]	[239]	9	hSpCas9	negative selection	12443962
4448200	4448223	17	+	28162770	OCIAML3	viability	CTGGTTCCAGACCCACCCCGGGG	SPNS3	ENSG00000182557	0.0226637201243311	[59]	[183]	0	hSpCas9	negative selection	12443963
4448219	4448242	17	+	28162770	OCIAML3	viability	GGGGAGCTGCCGAGACACAGGGG	SPNS3	ENSG00000182557	-0.14654866335294203	[21]	[59]	-1	hSpCas9	negative selection	12443964
4453151	4453174	17	-	28162770	OCIAML3	viability	CGAGAGCCAGGTAGAGGCAGGGG	SPNS3	ENSG00000182557	0.6690267655096306	[54]	[263]	6	hSpCas9	negative selection	12443965
4434053	4434076	17	-	28162770	OCIAML3	viability	GGAGGTGGGCGTGATGGGAGGGG	SPNS3	ENSG00000182557	-1.272079545436801	[23]	[29]	-7	hSpCas9	negative selection	12443966