Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 171546
• Symbol: SPTSSA
• Description: serine palmitoyltransferase small subunit A

DataSource: http://genomecrispr.dkfz.de/#!/results/SPTSSA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
34462199	34462222	14	-	26472758	Jiyoye	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.08265017513247191	[138]	[110]	0	hSpCas9	negative selection	156076
34462163	34462186	14	-	26472758	Jiyoye	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-0.980895070172701	[211]	[80]	-6	hSpCas9	negative selection	156077
34462102	34462125	14	-	26472758	Jiyoye	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	0.05570301100449582	[36]	[28]	0	hSpCas9	negative selection	156078
34462141	34462164	14	-	26472758	Jiyoye	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.17778711921528279	[65]	[43]	-1	hSpCas9	negative selection	156079
34462120	34462143	14	-	26472758	Jiyoye	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	0.4858873575199141	[106]	[112]	3	hSpCas9	negative selection	156080
34462094	34462117	14	+	26472758	Jiyoye	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.4871436862092886	[192]	[203]	3	hSpCas9	negative selection	156081
34435226	34435249	14	+	26472758	Jiyoye	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-1.0667558068265388	[74]	[26]	-6	hSpCas9	negative selection	156082
34435267	34435290	14	+	26472758	Jiyoye	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.21037467407216648	[148]	[129]	1	hSpCas9	negative selection	156083
34435275	34435298	14	-	26472758	Jiyoye	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.7006279080286414	[124]	[57]	-5	hSpCas9	negative selection	156084
34435293	34435316	14	-	26472758	Jiyoye	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	1.1988581453811484	[118]	[205]	7	hSpCas9	negative selection	156085
34462199	34462222	14	-	26472758	KBM7	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.2856342293656354	[611,371]	[195,176]	-3	hSpCas9	negative selection	347194
34462163	34462186	14	-	26472758	KBM7	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.2273085099433572	[598,531]	[76,145]	-7	hSpCas9	negative selection	347195
34462102	34462125	14	-	26472758	KBM7	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.7243785479676972	[271,130]	[91,22]	-6	hSpCas9	negative selection	347196
34462141	34462164	14	-	26472758	KBM7	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-1.396098654773663	[441,314]	[117,20]	-7	hSpCas9	negative selection	347197
34462120	34462143	14	-	26472758	KBM7	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.018516355156905	[455,498]	[75,37]	-8	hSpCas9	negative selection	347198
34462094	34462117	14	+	26472758	KBM7	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.6726657734499725	[1400,1140]	[366,377]	-5	hSpCas9	negative selection	347199
34435226	34435249	14	+	26472758	KBM7	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.29814758190052326	[233,214]	[68,100]	-3	hSpCas9	negative selection	347200
34435267	34435290	14	+	26472758	KBM7	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.23310782217923148	[777,772]	[327,296]	-2	hSpCas9	negative selection	347201
34435275	34435298	14	-	26472758	KBM7	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.30026234285309716	[466,362]	[209,109]	-3	hSpCas9	negative selection	347202
34435293	34435316	14	-	26472758	KBM7	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.26635855377947804	[840,762]	[360,270]	-3	hSpCas9	negative selection	347203
34462199	34462222	14	-	26472758	Raji	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	1.0957955610983876	[124]	[61]	8	hSpCas9	negative selection	538312
34462163	34462186	14	-	26472758	Raji	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.8257983580538468	[442]	[28]	-8	hSpCas9	negative selection	538313
34462102	34462125	14	-	26472758	Raji	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	0.41932754168833974	[86]	[26]	4	hSpCas9	negative selection	538314
34462141	34462164	14	-	26472758	Raji	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.7670855825425416	[175]	[23]	-5	hSpCas9	negative selection	538315
34462120	34462143	14	-	26472758	Raji	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.5141048413726708	[239]	[38]	-4	hSpCas9	negative selection	538316
34462094	34462117	14	+	26472758	Raji	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.13725406495573744	[477]	[121]	1	hSpCas9	negative selection	538317
34435226	34435249	14	+	26472758	Raji	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.023320156270994374	[126]	[28]	0	hSpCas9	negative selection	538318
34435267	34435290	14	+	26472758	Raji	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.1631454070071185	[385]	[39]	-7	hSpCas9	negative selection	538319
34435275	34435298	14	-	26472758	Raji	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.4931758203985753	[278]	[45]	-4	hSpCas9	negative selection	538320
34435293	34435316	14	-	26472758	Raji	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	1.0308419805006066	[328]	[155]	8	hSpCas9	negative selection	538321
34462199	34462222	14	-	26472758	K562	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.628231818210043	[396]	[517]	5	hSpCas9	negative selection	729430
34462163	34462186	14	-	26472758	K562	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.6480281311787497	[645]	[86]	-8	hSpCas9	negative selection	729431
34462102	34462125	14	-	26472758	K562	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.3003866465827265	[247]	[169]	-2	hSpCas9	negative selection	729432
34462141	34462164	14	-	26472758	K562	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	0.9571367755859759	[251]	[412]	7	hSpCas9	negative selection	729433
34462120	34462143	14	-	26472758	K562	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	0.3026136058364617	[412]	[429]	2	hSpCas9	negative selection	729434
34462094	34462117	14	+	26472758	K562	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.01444811403523083	[1017]	[867]	0	hSpCas9	negative selection	729435
34435226	34435249	14	+	26472758	K562	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.790907080572967	[75]	[110]	6	hSpCas9	negative selection	729436
34435267	34435290	14	+	26472758	K562	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.12311243144431316	[557]	[512]	0	hSpCas9	negative selection	729437
34435275	34435298	14	-	26472758	K562	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.6869369633673977	[467]	[635]	5	hSpCas9	negative selection	729438
34435293	34435316	14	-	26472758	K562	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.4090218578911302	[512]	[574]	3	hSpCas9	negative selection	729439
34462095	34462118	14	+	26627737	DLD1	viability	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	0.06801249426716205	[1152]	[409,390,338]	0	hSpCas9	negative selection	788441
34462126	34462149	14	+	26627737	DLD1	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.4536390365361388	[389]	[177,164,158]	4	hSpCas9	negative selection	788442
34462095	34462118	14	+	26627737	GBM cells	viability after 5 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.6223539505180808	[431]	[140,159]	-7	hSpCas9	negative selection	870756
34462126	34462149	14	+	26627737	GBM cells	viability after 5 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.2635165900097025	[215]	[94,97]	-4	hSpCas9	negative selection	870757
34462095	34462118	14	+	26627737	GBM cells	viability after 13 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.9430908334522476	[431]	[39,77]	-9	hSpCas9	negative selection	953071
34462126	34462149	14	+	26627737	GBM cells	viability after 13 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.6822334237172049	[215]	[77,68]	-7	hSpCas9	negative selection	953072
34462095	34462118	14	+	26627737	GBM cells	viability after 21 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-2.4747235956591744	[431]	[36,46]	-9	hSpCas9	negative selection	1035386
34462126	34462149	14	+	26627737	GBM cells	viability after 21 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-1.544733316906917	[215]	[34,44]	-8	hSpCas9	negative selection	1035387
34462095	34462118	14	+	26627737	RPE1	viability after 9 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-2.010424119179879	[2297]	[240,97]	-8	hSpCas9	negative selection	1117701
34462126	34462149	14	+	26627737	RPE1	viability after 9 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.8708497917931766	[321]	[79,318]	5	hSpCas9	negative selection	1117702
34462095	34462118	14	+	26627737	RPE1	viability after 12 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.6482091045506726	[2297]	[195,197]	-8	hSpCas9	negative selection	1200016
34462126	34462149	14	+	26627737	RPE1	viability after 12 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.6960376296412878	[321]	[15,92]	-5	hSpCas9	negative selection	1200017
34462095	34462118	14	+	26627737	RPE1	viability after 15 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.9376368513239284	[2297]	[186,152]	-8	hSpCas9	negative selection	1282331
34462126	34462149	14	+	26627737	RPE1	viability after 15 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-2.2407715490838167	[321]	[3,33]	-8	hSpCas9	negative selection	1282332
34462095	34462118	14	+	26627737	RPE1	viability after 18 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.2875409712281438	[2297]	[371,127]	-7	hSpCas9	negative selection	1364646
34462126	34462149	14	+	26627737	RPE1	viability after 18 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-1.683578187245296	[321]	[13,40]	-7	hSpCas9	negative selection	1364647
34462095	34462118	14	+	26627737	HeLa	viability after 8 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.7210108251714198	[865]	[240,269,180]	-6	hSpCas9	negative selection	1446961
34462126	34462149	14	+	26627737	HeLa	viability after 8 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.02011764984277503	[536]	[295,133,289]	0	hSpCas9	negative selection	1446962
34462095	34462118	14	+	26627737	HeLa	viability after 12 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.4042680183241871	[865]	[64,272,50]	-8	hSpCas9	negative selection	1529276
34462126	34462149	14	+	26627737	HeLa	viability after 12 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.9785167580173519	[536]	[26,238,55]	-7	hSpCas9	negative selection	1529277
34462095	34462118	14	+	26627737	HeLa	viability after 15 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.8822736289173356	[865]	[44,68,179]	-9	hSpCas9	negative selection	1611591
34462126	34462149	14	+	26627737	HeLa	viability after 15 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.5586397096829953	[536]	[126,200,114]	-5	hSpCas9	negative selection	1611592
34462095	34462118	14	+	26627737	HeLa	viability after 18 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.9017986250489085	[865]	[26,57,179]	-9	hSpCas9	negative selection	1693906
34462126	34462149	14	+	26627737	HeLa	viability after 18 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.60205784888235	[536]	[80,160,114]	-5	hSpCas9	negative selection	1693907
34462095	34462118	14	+	26627737	HCT116	viability after 6 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	1.0889576479074814	[1231]	[576,320]	6	hSpCas9	negative selection	1776221
34462126	34462149	14	+	26627737	HCT116	viability after 6 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	1.2665262806037285	[298]	[134,100]	6	hSpCas9	negative selection	1776222
34462095	34462118	14	+	26627737	HCT116	viability after 8 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.378979820575736	[615]	[131,165,93]	-9	hSpCas9	negative selection	1858536
34462126	34462149	14	+	26627737	HCT116	viability after 8 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.4106797226821131	[431]	[138,176,219]	-5	hSpCas9	negative selection	1858537
34462095	34462118	14	+	26627737	HCT116	viability after 9 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.3195704466656897	[1231]	[233,286]	-2	hSpCas9	negative selection	1940851
34462126	34462149	14	+	26627737	HCT116	viability after 9 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	1.4590948728849353	[298]	[166,260]	8	hSpCas9	negative selection	1940852
34462095	34462118	14	+	26627737	HCT116	viability after 12 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.5058522149882874	[615]	[87,185,71]	-9	hSpCas9	negative selection	2023166
34462126	34462149	14	+	26627737	HCT116	viability after 12 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-1.3574705927364783	[431]	[113,64,83]	-8	hSpCas9	negative selection	2023167
34462095	34462118	14	+	26627737	HCT116	viability after 15 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.6439629217502425	[615]	[93,108,133]	-9	hSpCas9	negative selection	2105481
34462126	34462149	14	+	26627737	HCT116	viability after 15 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.6018578672409048	[431]	[289,67,147]	-6	hSpCas9	negative selection	2105482
34462095	34462118	14	+	26627737	HCT116	viability after 18 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.1856837496868409	[615]	[52,177,159]	-8	hSpCas9	negative selection	2187796
34462126	34462149	14	+	26627737	HCT116	viability after 18 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.4689072606802484	[431]	[160,126,166]	-4	hSpCas9	negative selection	2187797
34452975	34452998	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTGTTTCAGGGGTGGCAGAGG	SPTSSA	ENSG00000165389	-0.03259604700857377	[52,10]	[8,2]	0	dCas9-VP64	positive selection	2416157
34438078	34438101	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCGAG	SPTSSA	ENSG00000165389	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430213
34447049	34447072	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGACGCGG	SPTSSA	ENSG00000165389	4.010018042841921	[201,101]	[623,445]	9	dCas9-VP64	positive selection	2473570
34452975	34452998	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTGTTTCAGGGGTGGCAGAGG	SPTSSA	ENSG00000165389	1.3752856989511004	[38,62]	[73,13]	7	dCas9-VP64	positive selection	2511412
34438078	34438101	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCGAG	SPTSSA	ENSG00000165389	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525468
34447049	34447072	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGACGCGG	SPTSSA	ENSG00000165389	1.087060795387326	[282,711]	[216,460]	7	dCas9-VP64	positive selection	2568825
34462199	34462222	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.055924436629777086	[3,2]	[3,1]	-1	hSpCas9	positive selection	3023621
34462135	34462158	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	-0.9111833096417633	[2,2]	[1,0]	-9	hSpCas9	positive selection	3023622
34462102	34462125	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	0.34614069201931186	[4,3]	[2,5]	7	hSpCas9	positive selection	3023623
34462141	34462164	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.41359453192478646	[4,4]	[3,1]	-5	hSpCas9	positive selection	3023624
34462199	34462222	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.30064372121490374	[3,3]	[2,0]	-4	hSpCas9	positive selection	3091479
34462135	34462158	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	-0.30755121716193995	[2,2]	[2,0]	-5	hSpCas9	positive selection	3091480
34462102	34462125	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.49655024471971654	[4,4]	[2,1]	-7	hSpCas9	positive selection	3091481
34462141	34462164	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	0.5786772694584277	[4,4]	[3,5]	8	hSpCas9	positive selection	3091482
34435267	34435290		+	24336571	A375	resistance to PLX after 7 days	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.32404823428329876	[9,8]	[6,7]	-8	hSpCas9	positive selection	3147360
34462126	34462149		+	24336571	A375	resistance to PLX after 7 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.6374784183006088	[11,11]	[8,5]	-9	hSpCas9	positive selection	3147361
34435267	34435290		+	24336571	A375	resistance to PLX after 14 days	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.6186124558140308	[6,4]	[3,3]	5	hSpCas9	positive selection	3205153
34462126	34462149		+	24336571	A375	resistance to PLX after 14 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.9402601765128724	[13,13]	[2,2]	-9	hSpCas9	positive selection	3205154
34435267	34435290		+	24336571	A375	viability after 7 days	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.04327071290398232	[9]	[9,8]	0	hSpCas9	negative selection	3262946
34462126	34462149		+	24336571	A375	viability after 7 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.5551041760617031	[18]	[11,11]	-7	hSpCas9	negative selection	3262947
34435267	34435290		+	24336571	A375	viability after 14 days	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.6750022346059095	[9]	[6,4]	-7	hSpCas9	negative selection	3320739
34462126	34462149		+	24336571	A375	viability after 14 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.3372834625774865	[18]	[13,13]	-4	hSpCas9	negative selection	3320740
34435262	34435285	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	3.556886493304743	[12,12]	[0,0]	9	hSpCas9	positive selection	3394879
34435293	34435316	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.8407058715146917	[273,273]	[0,0]	-6	hSpCas9	positive selection	3394880
34462112	34462135	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.6253168379160062	[235,235]	[0,0]	-4	hSpCas9	positive selection	3394881
34462199	34462222	14	-	26780180	HT29	viability (Avana library 4 designs)	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.525403416287508	[]	[]	2	hSpCas9	negative selection	3462290
34462135	34462158	14	-	26780180	HT29	viability (Avana library 4 designs)	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	1.95162549148875	[]	[]	7	hSpCas9	negative selection	3462291
34462102	34462125	14	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	2.25007612298662	[]	[]	7	hSpCas9	negative selection	3462292
34462141	34462164	14	-	26780180	HT29	viability (Avana library 4 designs)	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	1.54570416565189	[]	[]	6	hSpCas9	negative selection	3462293
34462141	34462164	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-7.10979529688852	[]	[]	-6	hSpCas9	negative selection	3563770
34462102	34462125	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	1.33091810793382	[]	[]	1	hSpCas9	negative selection	3563771
34462135	34462158	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	2.80600286832043	[]	[]	4	hSpCas9	negative selection	3563772
34462199	34462222	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	2.58456298877122	[]	[]	4	hSpCas9	negative selection	3563773
34462132	34462155	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCGTGACCAGCAGGTACTGG	SPTSSA	ENSG00000165389	0.518252107467232	[]	[]	0	hSpCas9	negative selection	3563774
34462095	34462118	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-2.04636568804147	[]	[]	-2	hSpCas9	negative selection	3563775
34462141	34462164	14	-	26780180	A375	viability (Avana lentiGuide)	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	2.79028803620854	[]	[]	3	hSpCas9	negative selection	3672429
34462102	34462125	14	-	26780180	A375	viability (Avana lentiGuide)	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	4.87222649605051	[]	[]	4	hSpCas9	negative selection	3672430
34462135	34462158	14	-	26780180	A375	viability (Avana lentiGuide)	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	4.69211670617777	[]	[]	4	hSpCas9	negative selection	3672431
34462199	34462222	14	-	26780180	A375	viability (Avana lentiGuide)	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	11.633036601702	[]	[]	7	hSpCas9	negative selection	3672432
34462132	34462155	14	+	26780180	A375	viability (Avana lentiGuide)	GCGCCGTGACCAGCAGGTACTGG	SPTSSA	ENSG00000165389	-2.10214498640444	[]	[]	-4	hSpCas9	negative selection	3672433
34462095	34462118	14	+	26780180	A375	viability (Avana lentiGuide)	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.272961600886806	[]	[]	0	hSpCas9	negative selection	3672434
34462141	34462164	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.8592721840086679	[6]	[3,2]	-8	hSpCas9	positive selection	3781036
34462102	34462125	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.0633678647226672	[4]	[3,0]	-9	hSpCas9	positive selection	3781037
34462135	34462158	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	-0.5560961180193243	[4]	[4,1]	-7	hSpCas9	positive selection	3781038
34462199	34462222	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.1578475393743387	[4]	[5,5]	4	hSpCas9	positive selection	3781039
34462132	34462155	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCGTGACCAGCAGGTACTGG	SPTSSA	ENSG00000165389	-0.3290075843838621	[3]	[3,1]	-5	hSpCas9	positive selection	3781040
34462095	34462118	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.4026290725436787	[4]	[2,0]	-9	hSpCas9	positive selection	3781041
34462141	34462164	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.46448840753524284	[6]	[3,4]	-6	hSpCas9	positive selection	3889643
34462102	34462125	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.9282571434066772	[6]	[2,1]	-8	hSpCas9	positive selection	3889644
34462135	34462158	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCAGTACCTGCTGGTCACGG	SPTSSA	ENSG00000165389	-0.5978479169851303	[4]	[2,1]	-6	hSpCas9	positive selection	3889645
34462199	34462222	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.3198712997826782	[5]	[3,2]	-4	hSpCas9	positive selection	3889646
34462132	34462155	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCGTGACCAGCAGGTACTGG	SPTSSA	ENSG00000165389	-0.23213234967415391	[5]	[3,3]	-3	hSpCas9	positive selection	3889647
34462095	34462118	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.703186370173603	[4]	[0,0]	-9	hSpCas9	positive selection	3889648
34462094	34462117	14	+	26780180	A375	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	1.64645919085419	[]	[]	8	hSpCas9	negative selection	3999339
34462112	34462135	14	-	26780180	A375	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	1.68702176150945	[]	[]	9	hSpCas9	negative selection	3999340
34435293	34435316	14	-	26780180	A375	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	2.15311353122755	[]	[]	9	hSpCas9	negative selection	3999341
34435267	34435290	14	+	26780180	A375	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.54583273884562	[]	[]	1	hSpCas9	negative selection	3999342
34435262	34435285	14	-	26780180	A375	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.327360189559045	[]	[]	0	hSpCas9	negative selection	3999343
34462126	34462149	14	+	26780180	A375	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	1.61988602731931	[]	[]	8	hSpCas9	negative selection	3999344
34462094	34462117	14	+	26780180	HT29	viability (GeCKOv2 library)	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	2.3374706006169	[]	[]	9	hSpCas9	negative selection	4107305
34462112	34462135	14	-	26780180	HT29	viability (GeCKOv2 library)	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	1.05412667220382	[]	[]	5	hSpCas9	negative selection	4107306
34435293	34435316	14	-	26780180	HT29	viability (GeCKOv2 library)	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	1.24833639083609	[]	[]	6	hSpCas9	negative selection	4107307
34435267	34435290	14	+	26780180	HT29	viability (GeCKOv2 library)	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	1.6323317529201	[]	[]	8	hSpCas9	negative selection	4107308
34435262	34435285	14	-	26780180	HT29	viability (GeCKOv2 library)	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.204461453699483	[]	[]	0	hSpCas9	negative selection	4107309
34462126	34462149	14	+	26780180	HT29	viability (GeCKOv2 library)	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	1.85526812312342	[]	[]	8	hSpCas9	negative selection	4107310
34435267	34435290	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.2777132328860134	[3]	[1,1]	-6	hSpCas9	positive selection	4173546
34462126	34462149	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.4597620497878715	[3]	[1,1]	-8	hSpCas9	positive selection	4173547
34435267	34435290	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	1.1056472241948596	[3]	[4,3,1,3]	8	hSpCas9	positive selection	4237568
34462126	34462149	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.3275650019781112	[3]	[0,0,0,3]	2	hSpCas9	positive selection	4237569
34435267	34435290	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.16436865899801806	[2]	[2,1]	-3	hSpCas9	positive selection	4300525
34462126	34462149	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.19436268043719893	[3]	[2,1]	-4	hSpCas9	positive selection	4300526
34462094	34462117	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.6417428062241328	[3]	[2,0]	-9	hSpCas9	positive selection	4300527
34435262	34435285	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.05177523976239451	[0]	[0,0]	1	hSpCas9	positive selection	4364780
34435293	34435316	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.08751072693952666	[3]	[4,2]	1	hSpCas9	positive selection	4364781
34462112	34462135	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.6026762953600447	[3]	[2,0]	-8	hSpCas9	positive selection	4364782
34435268	34435290	14	+	27760321	OCIAML3	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.3097025253094683	[334,287]	[64,140]	-8	hSpCas9	negative selection	4443059
34435280	34435302	14	-	27760321	OCIAML3	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.8564477046045804	[638,527]	[190,328]	-7	hSpCas9	negative selection	4443060
34435293	34435315	14	-	27760321	OCIAML3	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-1.518550270134362	[535,429]	[134,125]	-8	hSpCas9	negative selection	4443061
34462102	34462124	14	-	27760321	OCIAML3	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.5549729349939967	[604,562]	[138,176]	-8	hSpCas9	negative selection	4443062
34462120	34462142	14	-	27760321	OCIAML3	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.821243490187842	[632,504]	[99,157]	-9	hSpCas9	negative selection	4443063
34435268	34435290	14	+	27760321	OCIAML2	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.38311978797820245	[334,287]	[158,236]	-4	hSpCas9	negative selection	4526522
34435280	34435302	14	-	27760321	OCIAML2	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	0.15719569428624997	[638,527]	[504,548]	2	hSpCas9	negative selection	4526523
34435293	34435315	14	-	27760321	OCIAML2	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.3338186172078428	[535,429]	[417,583]	4	hSpCas9	negative selection	4526524
34462102	34462124	14	-	27760321	OCIAML2	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.4187049896441128	[604,562]	[105,269]	-8	hSpCas9	negative selection	4526525
34462120	34462142	14	-	27760321	OCIAML2	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.5620066450948282	[632,504]	[138,175]	-8	hSpCas9	negative selection	4526526
34435268	34435290	14	+	27760321	MV411	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.486534135043271	[334,287]	[5,173]	-7	hSpCas9	negative selection	4609985
34435280	34435302	14	-	27760321	MV411	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-1.2825308069129768	[638,527]	[119,213]	-7	hSpCas9	negative selection	4609986
34435293	34435315	14	-	27760321	MV411	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	1.2679266127684046	[535,429]	[1199,106]	8	hSpCas9	negative selection	4609987
34462102	34462124	14	-	27760321	MV411	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-2.5255362788906037	[604,562]	[10,150]	-9	hSpCas9	negative selection	4609988
34462120	34462142	14	-	27760321	MV411	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.847382303060578	[632,504]	[25,479]	-5	hSpCas9	negative selection	4609989
34435268	34435290	14	+	27760321	HL60	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.3400254823784057	[334,287]	[181,219]	-4	hSpCas9	negative selection	4693448
34435280	34435302	14	-	27760321	HL60	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	0.04135132804772007	[638,527]	[530,442]	0	hSpCas9	negative selection	4693449
34435293	34435315	14	-	27760321	HL60	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.13770165106142493	[535,429]	[292,423]	-1	hSpCas9	negative selection	4693450
34462102	34462124	14	-	27760321	HL60	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.9792331399531484	[604,562]	[88,154]	-9	hSpCas9	negative selection	4693451
34462120	34462142	14	-	27760321	HL60	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.38381944328336	[632,504]	[105,69]	-9	hSpCas9	negative selection	4693452
34435268	34435290	14	+	27760321	HT1080	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.7416176921436838	[287,224]	[167,173]	4	hSpCas9	negative selection	4776911
34435280	34435302	14	-	27760321	HT1080	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.7897503200337315	[527,411]	[198,8]	-3	hSpCas9	negative selection	4776912
34435293	34435315	14	-	27760321	HT1080	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-3.142854450756722	[429,335]	[1,33]	-7	hSpCas9	negative selection	4776913
34462102	34462124	14	-	27760321	HT1080	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.9900339337729025	[562,439]	[45,54]	-6	hSpCas9	negative selection	4776914
34462120	34462142	14	-	27760321	HT1080	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.5868533022103346	[504,393]	[82,33]	-5	hSpCas9	negative selection	4776915
34435268	34435290	14	+	27760321	HT29	viability after 7 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.5165397756051014	[287,224]	[758,394,306]	7	hSpCas9	negative selection	4860374
34435280	34435302	14	-	27760321	HT29	viability after 7 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.1230063462577044	[527,411]	[563,540,559]	-2	hSpCas9	negative selection	4860375
34435293	34435315	14	-	27760321	HT29	viability after 7 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.04194588475889338	[429,335]	[785,456,322]	0	hSpCas9	negative selection	4860376
34462102	34462124	14	-	27760321	HT29	viability after 7 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	0.1765389954615823	[562,439]	[673,600,896]	2	hSpCas9	negative selection	4860377
34462120	34462142	14	-	27760321	HT29	viability after 7 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	0.2340148781562077	[504,393]	[790,711,554]	3	hSpCas9	negative selection	4860378
34435268	34435290	14	+	27760321	HT29	viability after 25 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.20671747941893487	[287,224]	[209,174,393]	-2	hSpCas9	negative selection	4943837
34435280	34435302	14	-	27760321	HT29	viability after 25 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.20935777306906733	[527,411]	[315,486,614]	-2	hSpCas9	negative selection	4943838
34435293	34435315	14	-	27760321	HT29	viability after 25 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.6798758285698282	[429,335]	[180,302,348]	-5	hSpCas9	negative selection	4943839
34462102	34462124	14	-	27760321	HT29	viability after 25 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.0430812654534385	[562,439]	[199,282,364]	-6	hSpCas9	negative selection	4943840
34462120	34462142	14	-	27760321	HT29	viability after 25 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.1770391453732465	[504,393]	[159,189,347]	-7	hSpCas9	negative selection	4943841
34435268	34435290	14	+	27760321	HT29	viability after 22 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.4531778209108274	[287,224]	[356,73,214]	-4	hSpCas9	negative selection	5027300
34435280	34435302	14	-	27760321	HT29	viability after 22 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.4261566951279259	[527,411]	[341,341,531]	-4	hSpCas9	negative selection	5027301
34435293	34435315	14	-	27760321	HT29	viability after 22 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.788105541779301	[429,335]	[266,243,257]	-6	hSpCas9	negative selection	5027302
34462102	34462124	14	-	27760321	HT29	viability after 22 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.2853786411713877	[562,439]	[336,128,244]	-7	hSpCas9	negative selection	5027303
34462120	34462142	14	-	27760321	HT29	viability after 22 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.1517249412953139	[504,393]	[214,267,218]	-7	hSpCas9	negative selection	5027304
34435268	34435290	14	+	27760321	HT29	viability after 19 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.459987872825605	[287,224]	[292,113,239]	-4	hSpCas9	negative selection	5110763
34435280	34435302	14	-	27760321	HT29	viability after 19 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-0.12647491944700368	[527,411]	[602,487,400]	-1	hSpCas9	negative selection	5110764
34435293	34435315	14	-	27760321	HT29	viability after 19 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.0024660530943173276	[429,335]	[512,380,425]	0	hSpCas9	negative selection	5110765
34462102	34462124	14	-	27760321	HT29	viability after 19 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.5402859255162439	[562,439]	[672,407,140]	-5	hSpCas9	negative selection	5110766
34462120	34462142	14	-	27760321	HT29	viability after 19 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-1.1129489176776768	[504,393]	[237,185,286]	-7	hSpCas9	negative selection	5110767
34435268	34435290	14	+	27760321	HT29	viability after 16 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.4736856600370933	[287,224]	[181,192,242]	-5	hSpCas9	negative selection	5194226
34435280	34435302	14	-	27760321	HT29	viability after 16 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	0.08844104858257223	[527,411]	[581,493,604]	0	hSpCas9	negative selection	5194227
34435293	34435315	14	-	27760321	HT29	viability after 16 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-1.0404371379462443	[429,335]	[195,201,225]	-7	hSpCas9	negative selection	5194228
34462102	34462124	14	-	27760321	HT29	viability after 16 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.6755432759824646	[562,439]	[411,413,231]	-6	hSpCas9	negative selection	5194229
34462120	34462142	14	-	27760321	HT29	viability after 16 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.44416591750423773	[504,393]	[258,613,218]	-4	hSpCas9	negative selection	5194230
34435268	34435290	14	+	27760321	HT29	viability after 13 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.46892052896616154	[287,224]	[382,429,421]	6	hSpCas9	negative selection	5277689
34435280	34435302	14	-	27760321	HT29	viability after 13 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	0.30022718003510357	[527,411]	[729,733,556]	4	hSpCas9	negative selection	5277690
34435293	34435315	14	-	27760321	HT29	viability after 13 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.1928694658167895	[429,335]	[344,495,328]	-2	hSpCas9	negative selection	5277691
34462102	34462124	14	-	27760321	HT29	viability after 13 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.12361084573487524	[562,439]	[501,477,616]	-1	hSpCas9	negative selection	5277692
34462120	34462142	14	-	27760321	HT29	viability after 13 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.049194181389975444	[504,393]	[554,593,370]	0	hSpCas9	negative selection	5277693
34435268	34435290	14	+	27760321	HT29	viability after 10 days	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.1981770800087871	[287,224]	[432,212,449]	2	hSpCas9	negative selection	5361152
34435280	34435302	14	-	27760321	HT29	viability after 10 days	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	0.18404335318144377	[527,411]	[595,680,721]	2	hSpCas9	negative selection	5361153
34435293	34435315	14	-	27760321	HT29	viability after 10 days	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.8207309288970723	[429,335]	[244,297,269]	-7	hSpCas9	negative selection	5361154
34462102	34462124	14	-	27760321	HT29	viability after 10 days	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	0.10149921263286782	[562,439]	[562,711,739]	1	hSpCas9	negative selection	5361155
34462120	34462142	14	-	27760321	HT29	viability after 10 days	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.09195059131215005	[504,393]	[561,598,422]	-1	hSpCas9	negative selection	5361156
34435268	34435290	14	+	27760321	MOLM13	viability	TATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	1.0487426881258508	[334,287]	[516,230]	7	hSpCas9	negative selection	5444615
34435280	34435302	14	-	27760321	MOLM13	viability	CCATGCTGGTTTCCATTGTGGG	SPTSSA	ENSG00000165389	-1.6033573975748079	[638,527]	[55,151]	-7	hSpCas9	negative selection	5444616
34435293	34435315	14	-	27760321	MOLM13	viability	TACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-1.3724262797229279	[535,429]	[68,134]	-7	hSpCas9	negative selection	5444617
34462102	34462124	14	-	27760321	MOLM13	viability	CTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.96636562564065	[604,562]	[72,93]	-8	hSpCas9	negative selection	5444618
34462120	34462142	14	-	27760321	MOLM13	viability	GTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-8.317941300647723	[632,504]	[0,0]	-9	hSpCas9	negative selection	5444619
34462132	34462155	14	+	27661255	K562	viability	GCGCCGTGACCAGCAGGTACTGG	SPTSSA	ENSG00000165389	0.17719677963986005	[731,663]	[691,579]	6	dCas9-KRAB	negative selection	5514201
34462201	34462224	14	-	27661255	K562	viability	GCATCGCGGGAGGCGCATGGCGG	SPTSSA	ENSG00000165389	-0.05328502824144299	[493,543]	[481,327]	-2	dCas9-KRAB	negative selection	5514202
34462254	34462277	14	-	27661255	K562	viability	GGGGGCTTTAGGACGTGAGCGGG	SPTSSA	ENSG00000165389	0.0894334802822408	[857,977]	[874,695]	3	dCas9-KRAB	negative selection	5514203
34435267	34435290	14	+	27260156	BXPC3	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.15652806183558865	[392]	[308,349,413,412]	-4	hSpCas9	negative selection	5572985
34462126	34462149	14	+	27260156	BXPC3	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.7977344411176667	[487]	[328,321,261,246]	-9	hSpCas9	negative selection	5572986
34462094	34462117	14	+	27260156	BXPC3	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.2335239376583503	[629]	[497,506,661,584]	-5	hSpCas9	negative selection	5572987
34435262	34435285	14	-	27260156	BXPC3	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.1307166935524684	[22]	[16,22,36,29]	3	hSpCas9	negative selection	5637240
34435293	34435316	14	-	27260156	BXPC3	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.24792642822399114	[965]	[824,714,953,923]	-5	hSpCas9	negative selection	5637241
34462112	34462135	14	-	27260156	BXPC3	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.24187508398095908	[589]	[487,576,428,596]	-5	hSpCas9	negative selection	5637242
34435267	34435290	14	+	27260156	A673	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.006247300898692076	[392]	[470,594,430,389]	0	hSpCas9	negative selection	5694236
34462126	34462149	14	+	27260156	A673	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.2560365418413622	[487]	[515,463,454,532]	-6	hSpCas9	negative selection	5694237
34462094	34462117	14	+	27260156	A673	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.11320832466196695	[629]	[906,750,796,828]	2	hSpCas9	negative selection	5694238
34435262	34435285	14	-	27260156	A673	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.1556885652025226	[22]	[12,19,56,30]	4	hSpCas9	negative selection	5758491
34435293	34435316	14	-	27260156	A673	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.11166342950204844	[965]	[996,1088,1125,1069]	-3	hSpCas9	negative selection	5758492
34462112	34462135	14	-	27260156	A673	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.337706071110718	[589]	[619,555,520,550]	-7	hSpCas9	negative selection	5758493
34435267	34435290	14	+	27260156	A375	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.05007100531307607	[392]	[425,370,543,422]	0	hSpCas9	negative selection	5815487
34462126	34462149	14	+	27260156	A375	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.12755068352353272	[487]	[567,577,645,324]	-2	hSpCas9	negative selection	5815488
34462094	34462117	14	+	27260156	A375	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.2425894158233679	[629]	[976,811,686,981]	3	hSpCas9	negative selection	5815489
34435262	34435285	14	-	27260156	A375	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	1.2614086819884296	[22]	[30,176,57,12]	9	hSpCas9	negative selection	5879742
34435293	34435316	14	-	27260156	A375	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.30306331383749585	[965]	[929,1053,775,913]	-4	hSpCas9	negative selection	5879743
34462112	34462135	14	-	27260156	A375	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	0.08142271146404079	[589]	[757,643,548,926]	1	hSpCas9	negative selection	5879744
34435267	34435290	14	+	27260156	COLO741	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.1334084605353067	[392]	[596,372,416]	-3	hSpCas9	negative selection	5936738
34462126	34462149	14	+	27260156	COLO741	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.37575274739036757	[487]	[460,511,466]	-7	hSpCas9	negative selection	5936739
34462094	34462117	14	+	27260156	COLO741	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.26319674224735334	[629]	[1179,771,961]	5	hSpCas9	negative selection	5936740
34435262	34435285	14	-	27260156	COLO741	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.11065766024529022	[22]	[23,45,24]	2	hSpCas9	negative selection	6000993
34435293	34435316	14	-	27260156	COLO741	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.2983687837066422	[965]	[1158,975,894]	-6	hSpCas9	negative selection	6000994
34462112	34462135	14	-	27260156	COLO741	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.30146727966713327	[589]	[762,579,510]	-6	hSpCas9	negative selection	6000995
34435267	34435290	14	+	27260156	CAL120	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.03830742745539492	[392]	[513,537,456]	0	hSpCas9	negative selection	6057989
34462126	34462149	14	+	27260156	CAL120	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-1.1763910039139487	[487]	[267,165,369]	-9	hSpCas9	negative selection	6057990
34462094	34462117	14	+	27260156	CAL120	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.5712468735978172	[629]	[642,426,529]	-7	hSpCas9	negative selection	6057991
34435262	34435285	14	-	27260156	CAL120	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.4942484994741898	[22]	[5,43,8]	-6	hSpCas9	negative selection	6122244
34435293	34435316	14	-	27260156	CAL120	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.18728579855591843	[965]	[1381,1121,717]	-3	hSpCas9	negative selection	6122245
34462112	34462135	14	-	27260156	CAL120	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.9340123510209806	[589]	[440,212,504]	-8	hSpCas9	negative selection	6122246
34435267	34435290	14	+	27260156	CADOES1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.21797564178443005	[392]	[554,317,349,478]	3	hSpCas9	negative selection	6179240
34462126	34462149	14	+	27260156	CADOES1	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.09703976169438083	[487]	[520,446,360,365]	-2	hSpCas9	negative selection	6179241
34462094	34462117	14	+	27260156	CADOES1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.061942066143154006	[629]	[525,597,525,803]	1	hSpCas9	negative selection	6179242
34435262	34435285	14	-	27260156	CADOES1	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.3917155460461159	[22]	[3,31,30,45]	6	hSpCas9	negative selection	6243495
34435293	34435316	14	-	27260156	CADOES1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.33453178010816775	[965]	[763,710,607,768]	-5	hSpCas9	negative selection	6243496
34462112	34462135	14	-	27260156	CADOES1	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.21189141193509395	[589]	[639,415,481,351]	-4	hSpCas9	negative selection	6243497
34435267	34435290	14	+	27260156	EWS502	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.2768677630934511	[392]	[353,300,372,345]	-5	hSpCas9	negative selection	6300491
34462126	34462149	14	+	27260156	EWS502	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.5008011592846691	[487]	[450,283,457,1858]	8	hSpCas9	negative selection	6300492
34462094	34462117	14	+	27260156	EWS502	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.18891740957162073	[629]	[624,872,711,846]	3	hSpCas9	negative selection	6300493
34435262	34435285	14	-	27260156	EWS502	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.4446498072088234	[22]	[24,9,64,34]	7	hSpCas9	negative selection	6364746
34435293	34435316	14	-	27260156	EWS502	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.3562899700334775	[965]	[806,732,913,738]	-6	hSpCas9	negative selection	6364747
34462112	34462135	14	-	27260156	EWS502	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.5272127506918488	[589]	[409,408,458,460]	-7	hSpCas9	negative selection	6364748
34435267	34435290	14	+	27260156	EW8	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.0909201439931453	[392]	[519,202,277,221]	-2	hSpCas9	negative selection	6421742
34462126	34462149	14	+	27260156	EW8	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.3381355825225295	[487]	[430,380,194,276]	-6	hSpCas9	negative selection	6421743
34462094	34462117	14	+	27260156	EW8	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.040072245593567535	[629]	[608,324,543,624]	0	hSpCas9	negative selection	6421744
34435262	34435285	14	-	27260156	EW8	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.32005013583616915	[22]	[8,14,26,5]	-5	hSpCas9	negative selection	6485997
34435293	34435316	14	-	27260156	EW8	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.19416112999667445	[965]	[751,878,577,552]	-4	hSpCas9	negative selection	6485998
34462112	34462135	14	-	27260156	EW8	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.12429466240575276	[589]	[496,358,470,426]	-2	hSpCas9	negative selection	6485999
34435267	34435290	14	+	27260156	CORL105	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.2391255710029514	[392]	[360,389,439,374]	-4	hSpCas9	negative selection	6542993
34462126	34462149	14	+	27260156	CORL105	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.41506326093583196	[487]	[514,300,465,442]	-6	hSpCas9	negative selection	6542994
34462094	34462117	14	+	27260156	CORL105	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.08791629096598286	[629]	[977,706,765,689]	1	hSpCas9	negative selection	6542995
34435262	34435285	14	-	27260156	CORL105	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.9089318831322792	[22]	[13,19,18,4]	-9	hSpCas9	negative selection	6607248
34435293	34435316	14	-	27260156	CORL105	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.2542614446843968	[965]	[968,941,965,918]	-5	hSpCas9	negative selection	6607249
34462112	34462135	14	-	27260156	CORL105	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.6838503950090867	[589]	[406,451,501,368]	-8	hSpCas9	negative selection	6607250
34435267	34435290	14	+	27260156	HS294T	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.0344662048642555	[392]	[145,161,159,119]	0	hSpCas9	negative selection	6664244
34462126	34462149	14	+	27260156	HS294T	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.36989998864696144	[487]	[121,113,169,187]	-5	hSpCas9	negative selection	6664245
34462094	34462117	14	+	27260156	HS294T	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.6180694008181384	[629]	[654,227,283,290]	7	hSpCas9	negative selection	6664246
34435262	34435285	14	-	27260156	HS294T	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.9094701634080051	[22]	[4,2,5,4]	-8	hSpCas9	negative selection	6728499
34435293	34435316	14	-	27260156	HS294T	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.1756257919184241	[965]	[216,329,508,265]	-2	hSpCas9	negative selection	6728500
34462112	34462135	14	-	27260156	HS294T	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.15778195501741377	[589]	[207,175,213,222]	-2	hSpCas9	negative selection	6728501
34435267	34435290	14	+	27260156	HCC44	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.45510039485623016	[392]	[311,243,452,317]	-6	hSpCas9	negative selection	6785495
34462126	34462149	14	+	27260156	HCC44	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.8649608082839036	[487]	[387,123,493,270]	-8	hSpCas9	negative selection	6785496
34462094	34462117	14	+	27260156	HCC44	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.137357839358961	[629]	[768,533,628,676]	-2	hSpCas9	negative selection	6785497
34435262	34435285	14	-	27260156	HCC44	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.6813494376075635	[22]	[1,0,17,43]	-7	hSpCas9	negative selection	6849750
34435293	34435316	14	-	27260156	HCC44	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.29488631762491224	[965]	[1122,858,656,900]	-5	hSpCas9	negative selection	6849751
34462112	34462135	14	-	27260156	HCC44	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.2676408679302247	[589]	[776,543,389,496]	-4	hSpCas9	negative selection	6849752
34435267	34435290	14	+	27260156	G402	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.36852929384462896	[392]	[779,757,489,483]	4	hSpCas9	negative selection	6906746
34462126	34462149	14	+	27260156	G402	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.09940722029318635	[487]	[510,694,657,367]	-1	hSpCas9	negative selection	6906747
34462094	34462117	14	+	27260156	G402	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.45910637241734786	[629]	[1847,774,771,931]	6	hSpCas9	negative selection	6906748
34435262	34435285	14	-	27260156	G402	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.26580930477620424	[22]	[24,6,3,54]	-3	hSpCas9	negative selection	6971001
34435293	34435316	14	-	27260156	G402	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.17671006232260789	[965]	[980,1769,1347,1205]	2	hSpCas9	negative selection	6971002
34462112	34462135	14	-	27260156	G402	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	0.24902784698125063	[589]	[1306,649,1143,393]	3	hSpCas9	negative selection	6971003
34435267	34435290	14	+	27260156	L33	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.28781154397005476	[392]	[393,235,327,429]	6	hSpCas9	negative selection	7027997
34462126	34462149	14	+	27260156	L33	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	0.02511080798803566	[487]	[456,214,274,566]	0	hSpCas9	negative selection	7027998
34462094	34462117	14	+	27260156	L33	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.07742012843447404	[629]	[758,215,350,539]	-2	hSpCas9	negative selection	7027999
34435262	34435285	14	-	27260156	L33	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.8621280151793638	[22]	[17,2,6,13]	-9	hSpCas9	negative selection	7092252
34435293	34435316	14	-	27260156	L33	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.17913812330709677	[965]	[809,335,604,821]	-4	hSpCas9	negative selection	7092253
34462112	34462135	14	-	27260156	L33	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.44776712298142146	[589]	[381,190,270,451]	-8	hSpCas9	negative selection	7092254
34435267	34435290	14	+	27260156	K562	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.2313468706935513	[392]	[311,226,304,335]	-3	hSpCas9	negative selection	7149248
34462126	34462149	14	+	27260156	K562	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.25885983522595263	[487]	[206,760,289,213]	-3	hSpCas9	negative selection	7149249
34462094	34462117	14	+	27260156	K562	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.3663813304238516	[629]	[483,365,416,462]	-4	hSpCas9	negative selection	7149250
34435262	34435285	14	-	27260156	K562	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	1.252800667281437	[22]	[149,51,0,4]	9	hSpCas9	negative selection	7213503
34435293	34435316	14	-	27260156	K562	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.02081440283164948	[965]	[487,829,1274,762]	0	hSpCas9	negative selection	7213504
34462112	34462135	14	-	27260156	K562	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.44596236907287323	[589]	[443,333,431,333]	-5	hSpCas9	negative selection	7213505
34435267	34435290	14	+	27260156	HT29	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.05284034405083332	[392]	[544,463,486,361]	-1	hSpCas9	negative selection	7270499
34462126	34462149	14	+	27260156	HT29	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.22516701957010743	[487]	[525,562,395,542]	-4	hSpCas9	negative selection	7270500
34462094	34462117	14	+	27260156	HT29	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.06997443082063715	[629]	[1042,956,578,677]	1	hSpCas9	negative selection	7270501
34435262	34435285	14	-	27260156	HT29	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.4669215929468624	[22]	[20,18,22,17]	-7	hSpCas9	negative selection	7334754
34435293	34435316	14	-	27260156	HT29	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.3434765586261025	[965]	[992,1113,938,698]	-6	hSpCas9	negative selection	7334755
34462112	34462135	14	-	27260156	HT29	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.3668058253716016	[589]	[581,478,651,508]	-6	hSpCas9	negative selection	7334756
34435267	34435290	14	+	27260156	MHHES1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.1793349191151381	[392]	[514,406,382,289]	-3	hSpCas9	negative selection	7391750
34462126	34462149	14	+	27260156	MHHES1	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.44443872299274495	[487]	[486,546,280,331]	-7	hSpCas9	negative selection	7391751
34462094	34462117	14	+	27260156	MHHES1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.06126811161832152	[629]	[833,851,759,562]	1	hSpCas9	negative selection	7391752
34435262	34435285	14	-	27260156	MHHES1	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.2820460338573536	[22]	[65,6,22,30]	5	hSpCas9	negative selection	7456005
34435293	34435316	14	-	27260156	MHHES1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.15546443338460403	[965]	[889,1485,954,667]	-3	hSpCas9	negative selection	7456006
34462112	34462135	14	-	27260156	MHHES1	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.4780146468711828	[589]	[687,504,354,395]	-7	hSpCas9	negative selection	7456007
34435267	34435290	14	+	27260156	MEWO	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.19464216168657544	[392]	[340,231,394]	-4	hSpCas9	negative selection	7513001
34462126	34462149	14	+	27260156	MEWO	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.0778263532190564	[487]	[379,524,381]	-2	hSpCas9	negative selection	7513002
34462094	34462117	14	+	27260156	MEWO	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.05105294838395513	[629]	[503,632,673]	1	hSpCas9	negative selection	7513003
34435262	34435285	14	-	27260156	MEWO	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.6272772326838765	[22]	[44,29,26]	9	hSpCas9	negative selection	7577256
34435293	34435316	14	-	27260156	MEWO	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.025858762472601438	[965]	[874,786,1089]	0	hSpCas9	negative selection	7577257
34462112	34462135	14	-	27260156	MEWO	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.13281080804887868	[589]	[655,452,430]	-3	hSpCas9	negative selection	7577258
34435267	34435290	14	+	27260156	LNCAPCLONEFGC	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.26335586028807906	[392]	[242,293,313,338]	-4	hSpCas9	negative selection	7634252
34462126	34462149	14	+	27260156	LNCAPCLONEFGC	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.023945625554627273	[487]	[341,444,488,471]	0	hSpCas9	negative selection	7634253
34462094	34462117	14	+	27260156	LNCAPCLONEFGC	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.06851861907477108	[629]	[726,387,801,517]	1	hSpCas9	negative selection	7634254
34435262	34435285	14	-	27260156	LNCAPCLONEFGC	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.38878997266736093	[22]	[8,24,7,19]	-6	hSpCas9	negative selection	7698507
34435293	34435316	14	-	27260156	LNCAPCLONEFGC	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.2563497233814035	[965]	[690,701,666,862]	-4	hSpCas9	negative selection	7698508
34462112	34462135	14	-	27260156	LNCAPCLONEFGC	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.3156673120762865	[589]	[460,413,423,417]	-5	hSpCas9	negative selection	7698509
34435267	34435290	14	+	27260156	PANC0327	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.3422244274550368	[392]	[175,58,142,185]	-9	hSpCas9	negative selection	7755503
34462126	34462149	14	+	27260156	PANC0327	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-1.606369768298214	[487]	[267,69,98,151]	-9	hSpCas9	negative selection	7755504
34462094	34462117	14	+	27260156	PANC0327	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.9601317215702535	[629]	[332,304,260,252]	-8	hSpCas9	negative selection	7755505
34435262	34435285	14	-	27260156	PANC0327	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-2.7714521358858484	[22]	[4,3,0,1]	-9	hSpCas9	negative selection	7819758
34435293	34435316	14	-	27260156	PANC0327	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.5713426041973075	[965]	[509,484,531,788]	-7	hSpCas9	negative selection	7819759
34462112	34462135	14	-	27260156	PANC0327	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.8965292032608616	[589]	[490,205,257,197]	-8	hSpCas9	negative selection	7819760
34435267	34435290	14	+	27260156	NCIH2009	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.1737485359014591	[392]	[467,420,567]	-2	hSpCas9	negative selection	7876754
34462126	34462149	14	+	27260156	NCIH2009	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.7064619058138147	[487]	[582,275,428]	-7	hSpCas9	negative selection	7876755
34462094	34462117	14	+	27260156	NCIH2009	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.49036531017858354	[629]	[703,513,677]	-6	hSpCas9	negative selection	7876756
34435262	34435285	14	-	27260156	NCIH2009	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.0663737588494131	[22]	[42,18,40]	0	hSpCas9	negative selection	7941009
34435293	34435316	14	-	27260156	NCIH2009	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.22923167266524447	[965]	[1377,928,1193]	-3	hSpCas9	negative selection	7941010
34462112	34462135	14	-	27260156	NCIH2009	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.8707810563814806	[589]	[603,277,502]	-8	hSpCas9	negative selection	7941011
34435267	34435290	14	+	27260156	NCIH1373	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.5868200055331425	[392]	[237,164,224,148]	-5	hSpCas9	negative selection	7998005
34462126	34462149	14	+	27260156	NCIH1373	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.5380736261676197	[487]	[264,331,364,141]	-5	hSpCas9	negative selection	7998006
34462094	34462117	14	+	27260156	NCIH1373	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.258169529432151	[629]	[1082,388,433,422]	2	hSpCas9	negative selection	7998007
34435262	34435285	14	-	27260156	NCIH1373	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.6311966155595656	[22]	[5,3,118,6]	6	hSpCas9	negative selection	8062260
34435293	34435316	14	-	27260156	NCIH1373	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.7076023736234653	[965]	[946,565,579,159]	-6	hSpCas9	negative selection	8062261
34462112	34462135	14	-	27260156	NCIH1373	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.11590234007581482	[589]	[1065,412,375,179]	-1	hSpCas9	negative selection	8062262
34435267	34435290	14	+	27260156	PATU8902	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.6176129044378393	[392]	[393,556,278,194]	-5	hSpCas9	negative selection	8119256
34462126	34462149	14	+	27260156	PATU8902	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.5370878601488741	[487]	[397,431,564,447]	-5	hSpCas9	negative selection	8119257
34462094	34462117	14	+	27260156	PATU8902	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.12993694179363102	[629]	[853,760,843,1464]	1	hSpCas9	negative selection	8119258
34435262	34435285	14	-	27260156	PATU8902	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.10318318750506883	[22]	[37,12,1,78]	-1	hSpCas9	negative selection	8183511
34435293	34435316	14	-	27260156	PATU8902	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.7307415282509446	[965]	[619,953,671,1058]	-6	hSpCas9	negative selection	8183512
34462112	34462135	14	-	27260156	PATU8902	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.35469349244589227	[589]	[677,847,558,482]	-4	hSpCas9	negative selection	8183513
34435267	34435290	14	+	27260156	PANC1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.38916721054346354	[392]	[203,431,202,228]	-6	hSpCas9	negative selection	8240507
34462126	34462149	14	+	27260156	PANC1	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.7056811303396427	[487]	[194,236,209,360]	-7	hSpCas9	negative selection	8240508
34462094	34462117	14	+	27260156	PANC1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.06755756212039243	[629]	[533,826,374,573]	1	hSpCas9	negative selection	8240509
34435262	34435285	14	-	27260156	PANC1	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-2.2689614130201914	[22]	[2,3,2,5]	-9	hSpCas9	negative selection	8304762
34435293	34435316	14	-	27260156	PANC1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.4600967653423237	[965]	[482,798,632,540]	-6	hSpCas9	negative selection	8304763
34462112	34462135	14	-	27260156	PANC1	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.4537265993571347	[589]	[355,602,293,282]	-6	hSpCas9	negative selection	8304764
34435267	34435290	14	+	27260156	PANC0813	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.3160600058934821	[392]	[485,375,332,301]	-5	hSpCas9	negative selection	8361758
34462126	34462149	14	+	27260156	PANC0813	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.8479883538002235	[487]	[274,288,358,344]	-8	hSpCas9	negative selection	8361759
34462094	34462117	14	+	27260156	PANC0813	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.5700450605264192	[629]	[614,466,482,441]	-7	hSpCas9	negative selection	8361760
34435262	34435285	14	-	27260156	PANC0813	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-3.1688845892930484	[22]	[2,4,0,2]	-9	hSpCas9	negative selection	8426013
34435293	34435316	14	-	27260156	PANC0813	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.7070019503237055	[965]	[627,640,780,721]	-7	hSpCas9	negative selection	8426014
34462112	34462135	14	-	27260156	PANC0813	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-1.4058343877843593	[589]	[320,234,230,263]	-9	hSpCas9	negative selection	8426015
34435267	34435290	14	+	27260156	RDES	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.10765082407629883	[392]	[378,388,495,413]	-2	hSpCas9	negative selection	8483009
34462126	34462149	14	+	27260156	RDES	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.35983724459860544	[487]	[380,410,409,566]	-6	hSpCas9	negative selection	8483010
34462094	34462117	14	+	27260156	RDES	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.21908177028871156	[629]	[599,785,846,1234]	3	hSpCas9	negative selection	8483011
34435262	34435285	14	-	27260156	RDES	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.930355272276981	[22]	[26,48,70,60]	9	hSpCas9	negative selection	8547264
34435293	34435316	14	-	27260156	RDES	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.024123450545683545	[965]	[986,1018,1208,1164]	0	hSpCas9	negative selection	8547265
34462112	34462135	14	-	27260156	RDES	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.14101732475625678	[589]	[487,436,731,875]	-2	hSpCas9	negative selection	8547266
34435267	34435290	14	+	27260156	PC3	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.19395538113435806	[392]	[231,386,664,663]	4	hSpCas9	negative selection	8604260
34462126	34462149	14	+	27260156	PC3	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.12311302094701407	[487]	[197,356,927,579]	-3	hSpCas9	negative selection	8604261
34462094	34462117	14	+	27260156	PC3	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.131925488953215	[629]	[275,644,1579,739]	3	hSpCas9	negative selection	8604262
34435262	34435285	14	-	27260156	PC3	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.11401105998336813	[22]	[27,9,68,3]	2	hSpCas9	negative selection	8668515
34435293	34435316	14	-	27260156	PC3	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.19895644061812812	[965]	[538,775,1399,913]	-4	hSpCas9	negative selection	8668516
34462112	34462135	14	-	27260156	PC3	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.1321959853062441	[589]	[412,412,970,516]	-3	hSpCas9	negative selection	8668517
34435267	34435290	14	+	27260156	PATU8988T	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.24537293050954018	[392]	[197,360,179,567]	-4	hSpCas9	negative selection	8725511
34462126	34462149	14	+	27260156	PATU8988T	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.7762203996553443	[487]	[246,302,276,276]	-8	hSpCas9	negative selection	8725512
34462094	34462117	14	+	27260156	PATU8988T	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.20329804610674346	[629]	[492,688,414,534]	-3	hSpCas9	negative selection	8725513
34435262	34435285	14	-	27260156	PATU8988T	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-1.5331676325972188	[22]	[2,20,0,6]	-9	hSpCas9	negative selection	8789766
34435293	34435316	14	-	27260156	PATU8988T	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.2881388316781368	[965]	[758,882,723,697]	-5	hSpCas9	negative selection	8789767
34462112	34462135	14	-	27260156	PATU8988T	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.24868533725074116	[589]	[293,641,536,458]	-4	hSpCas9	negative selection	8789768
34435267	34435290	14	+	27260156	T47D	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.033282503894244336	[392]	[478,501,417,472]	0	hSpCas9	negative selection	8846762
34462126	34462149	14	+	27260156	T47D	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.1543291801605414	[487]	[572,461,457,556]	-3	hSpCas9	negative selection	8846763
34462094	34462117	14	+	27260156	T47D	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.07463818107959463	[629]	[900,671,754,772]	1	hSpCas9	negative selection	8846764
34435262	34435285	14	-	27260156	T47D	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.2985047601107462	[22]	[30,34,24,40]	6	hSpCas9	negative selection	8911017
34435293	34435316	14	-	27260156	T47D	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.09241697549613426	[965]	[1118,1020,958,1129]	-2	hSpCas9	negative selection	8911018
34462112	34462135	14	-	27260156	T47D	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.08501044563062737	[589]	[642,570,676,708]	-2	hSpCas9	negative selection	8911019
34435267	34435290	14	+	27260156	SU8686	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.11130016311512198	[392]	[349,308,361,439]	-2	hSpCas9	negative selection	8968013
34462126	34462149	14	+	27260156	SU8686	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.23238179727964553	[487]	[329,329,463,566]	-4	hSpCas9	negative selection	8968014
34462094	34462117	14	+	27260156	SU8686	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.010395141170624733	[629]	[472,637,705,729]	0	hSpCas9	negative selection	8968015
34435262	34435285	14	-	27260156	SU8686	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	-0.5815297650771516	[22]	[17,3,7,34]	-7	hSpCas9	negative selection	9032268
34435293	34435316	14	-	27260156	SU8686	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.16034551848731982	[965]	[856,751,837,1012]	-3	hSpCas9	negative selection	9032269
34462112	34462135	14	-	27260156	SU8686	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.24385152739147914	[589]	[558,507,431,455]	-4	hSpCas9	negative selection	9032270
34435267	34435290	14	+	27260156	SKES1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.010021331957755064	[392]	[456,373,368,363]	0	hSpCas9	negative selection	9089264
34462126	34462149	14	+	27260156	SKES1	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.0025462909329491412	[487]	[759,449,392,382]	0	hSpCas9	negative selection	9089265
34462094	34462117	14	+	27260156	SKES1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.17206537293523216	[629]	[642,878,736,590]	3	hSpCas9	negative selection	9089266
34435262	34435285	14	-	27260156	SKES1	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.6317490393303968	[22]	[41,75,13,17]	9	hSpCas9	negative selection	9153519
34435293	34435316	14	-	27260156	SKES1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.28984263126655274	[965]	[1017,793,767,617]	-6	hSpCas9	negative selection	9153520
34462112	34462135	14	-	27260156	SKES1	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.021478690069714923	[589]	[805,573,703,292]	0	hSpCas9	negative selection	9153521
34435267	34435290	14	+	27260156	TOV112D	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	0.2047814812094651	[392]	[333,636,501,377]	4	hSpCas9	negative selection	9210515
34462126	34462149	14	+	27260156	TOV112D	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.23263848893229874	[487]	[478,364,433,378]	-4	hSpCas9	negative selection	9210516
34462094	34462117	14	+	27260156	TOV112D	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.21634364025064545	[629]	[809,921,808,450]	4	hSpCas9	negative selection	9210517
34435262	34435285	14	-	27260156	TOV112D	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	1.201893687692074	[22]	[82,60,41,30]	9	hSpCas9	negative selection	9274770
34435293	34435316	14	-	27260156	TOV112D	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.037458326456556446	[965]	[1080,1198,803,764]	0	hSpCas9	negative selection	9274771
34462112	34462135	14	-	27260156	TOV112D	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	0.16267485875237853	[589]	[586,998,564,572]	3	hSpCas9	negative selection	9274772
34435267	34435290	14	+	27260156	TC71	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.017972133100089493	[392]	[352,443,415,454]	0	hSpCas9	negative selection	9331766
34462126	34462149	14	+	27260156	TC71	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.07284094116861156	[487]	[530,508,363,594]	-2	hSpCas9	negative selection	9331767
34462094	34462117	14	+	27260156	TC71	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.020420153377438244	[629]	[536,831,697,674]	0	hSpCas9	negative selection	9331768
34435262	34435285	14	-	27260156	TC71	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.8103072702805831	[22]	[35,47,25,64]	9	hSpCas9	negative selection	9396021
34435293	34435316	14	-	27260156	TC71	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.10657103355628916	[965]	[998,994,816,1044]	-3	hSpCas9	negative selection	9396022
34462112	34462135	14	-	27260156	TC71	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.21213934154312608	[589]	[531,447,490,725]	-5	hSpCas9	negative selection	9396023
34435267	34435290	14	+	27260156	TC32	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.24082133348159457	[392]	[223,291,444,311]	-4	hSpCas9	negative selection	9453017
34462126	34462149	14	+	27260156	TC32	viability	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.48217780452760467	[487]	[299,349,310,321]	-7	hSpCas9	negative selection	9453018
34462094	34462117	14	+	27260156	TC32	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	0.18182150098962213	[629]	[903,383,790,665]	3	hSpCas9	negative selection	9453019
34435262	34435285	14	-	27260156	TC32	viability	GTGGGGATGGCACTATACACAGG	SPTSSA	ENSG00000165389	0.18852811882433063	[22]	[12,39,10,25]	3	hSpCas9	negative selection	9517272
34435293	34435316	14	-	27260156	TC32	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.35086606204284765	[965]	[743,453,874,862]	-6	hSpCas9	negative selection	9517273
34462112	34462135	14	-	27260156	TC32	viability	CGCTCTACATGCTGGAGCCCTGG	SPTSSA	ENSG00000165389	-0.09006028378379691	[589]	[499,506,603,456]	-1	hSpCas9	negative selection	9517274
34462095	34462118	14	+	27869803	HPAFII	viability after 27 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-3.8227523635283314	[459]	[27,7,NaN]	-9	hSpCas9	negative selection	9551447
34462126	34462149	14	+	27869803	HPAFII	viability after 27 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-4.173568443279984	[336]	[11,7,NaN]	-9	hSpCas9	negative selection	9551448
34462095	34462118	14	+	27869803	HPAFII	viability after 15 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.7827467608936298	[459]	[570,110,NaN]	-7	hSpCas9	negative selection	9633896
34462126	34462149	14	+	27869803	HPAFII	viability after 15 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-2.1800854567566956	[336]	[119,54,NaN]	-9	hSpCas9	negative selection	9633897
34462095	34462118	14	+	27869803	ASPC1	viability after 36 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-0.8842943018525787	[960]	[218,169,162]	-7	hSpCas9	negative selection	9716345
34462126	34462149	14	+	27869803	ASPC1	viability after 36 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-2.100297070164053	[758]	[94,82,20]	-9	hSpCas9	negative selection	9716346
34462095	34462118	14	+	27869803	PATU8988S	viability after 35 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.6963007298259185	[1109]	[115,159,NaN]	-8	hSpCas9	negative selection	9798794
34462126	34462149	14	+	27869803	PATU8988S	viability after 35 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.5660017603001753	[607]	[124,205,NaN]	-5	hSpCas9	negative selection	9798795
34462095	34462118	14	+	27869803	PATU8988S	viability after 31 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-1.1956749021343707	[1109]	[161,232,NaN]	-8	hSpCas9	negative selection	9881243
34462126	34462149	14	+	27869803	PATU8988S	viability after 31 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-0.2015554622689819	[607]	[139,300,NaN]	-2	hSpCas9	negative selection	9881244
34462095	34462118	14	+	27869803	HPAFII	viability after 35 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-3.1788399656008783	[459]	[44,3,NaN]	-8	hSpCas9	negative selection	9963692
34462126	34462149	14	+	27869803	HPAFII	viability after 35 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-2.9396159655647938	[336]	[25,17,NaN]	-8	hSpCas9	negative selection	9963693
34462095	34462118	14	+	27869803	HPAFII	viability after 31 days	CTGAACACCGTCCGCTCCCAGGG	SPTSSA	ENSG00000165389	-2.4407454152959165	[459]	[70,21,NaN]	-8	hSpCas9	negative selection	10046141
34462126	34462149	14	+	27869803	HPAFII	viability after 31 days	TGTAGAGCGCCGTGACCAGCAGG	SPTSSA	ENSG00000165389	-7.5632335815066005	[336]	[0,0,NaN]	-9	hSpCas9	negative selection	10046142
34462199	34462222	14	-	28162770	P31FUJ	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.0688534954467227	[128]	[158]	0	hSpCas9	negative selection	10242723
34462163	34462186	14	-	28162770	P31FUJ	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.36900658801269	[443]	[100]	-8	hSpCas9	negative selection	10242724
34462102	34462125	14	-	28162770	P31FUJ	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-4.8533886148662555	[122]	[4]	-9	hSpCas9	negative selection	10242725
34462141	34462164	14	-	28162770	P31FUJ	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.9697677985805846	[74]	[44]	-6	hSpCas9	negative selection	10242726
34462120	34462143	14	-	28162770	P31FUJ	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.127092763243264	[170]	[45]	-8	hSpCas9	negative selection	10242727
34462094	34462117	14	+	28162770	P31FUJ	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-2.969767798580585	[439]	[65]	-9	hSpCas9	negative selection	10242728
34435226	34435249	14	+	28162770	P31FUJ	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.3816655903288615	[101]	[91]	-3	hSpCas9	negative selection	10242729
34435267	34435290	14	+	28162770	P31FUJ	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.6647031413268728	[544]	[403]	-5	hSpCas9	negative selection	10242730
34435275	34435298	14	-	28162770	P31FUJ	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.2865734608553593	[245]	[236]	-3	hSpCas9	negative selection	10242731
34435293	34435316	14	-	28162770	P31FUJ	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.4754354181884512	[322]	[272]	-4	hSpCas9	negative selection	10242732
34462199	34462222	14	-	28162770	TF1	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10412089
34462163	34462186	14	-	28162770	TF1	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10412090
34462102	34462125	14	-	28162770	TF1	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10412091
34462141	34462164	14	-	28162770	TF1	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10412092
34462120	34462143	14	-	28162770	TF1	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10412093
34462094	34462117	14	+	28162770	TF1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[459]	1	hSpCas9	negative selection	10412094
34435226	34435249	14	+	28162770	TF1	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10412095
34435267	34435290	14	+	28162770	TF1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10412096
34435275	34435298	14	-	28162770	TF1	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10412097
34435293	34435316	14	-	28162770	TF1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	NaN	[NaN]	[322]	1	hSpCas9	negative selection	10412098
34462199	34462222	14	-	28162770	SKM1	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.0038400210078186614	[37]	[66]	0	hSpCas9	negative selection	10581455
34462163	34462186	14	-	28162770	SKM1	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-0.7761980084088808	[92]	[95]	-5	hSpCas9	negative selection	10581456
34462102	34462125	14	-	28162770	SKM1	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.143929792909368	[24]	[19]	-7	hSpCas9	negative selection	10581457
34462141	34462164	14	-	28162770	SKM1	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-4.281433316659303	[32]	[2]	-9	hSpCas9	negative selection	10581458
34462120	34462143	14	-	28162770	SKM1	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.6964708159381465	[43]	[11]	-9	hSpCas9	negative selection	10581459
34462094	34462117	14	+	28162770	SKM1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-2.9374789154419414	[168]	[38]	-9	hSpCas9	negative selection	10581460
34435226	34435249	14	+	28162770	SKM1	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	1.4617912679785858	[22]	[111]	9	hSpCas9	negative selection	10581461
34435267	34435290	14	+	28162770	SKM1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.3203418439954109	[100]	[142]	-3	hSpCas9	negative selection	10581462
34435275	34435298	14	-	28162770	SKM1	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.28335130212422294	[65]	[141]	2	hSpCas9	negative selection	10581463
34435293	34435316	14	-	28162770	SKM1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.3379941861765752	[80]	[180]	3	hSpCas9	negative selection	10581464
34462199	34462222	14	-	28162770	SKM1	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.0038400210078186614	[37]	[66]	0	hSpCas9	negative selection	10750821
34462163	34462186	14	-	28162770	SKM1	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-0.7761980084088808	[92]	[95]	-5	hSpCas9	negative selection	10750822
34462102	34462125	14	-	28162770	SKM1	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.143929792909368	[24]	[19]	-7	hSpCas9	negative selection	10750823
34462141	34462164	14	-	28162770	SKM1	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-4.281433316659303	[32]	[2]	-9	hSpCas9	negative selection	10750824
34462120	34462143	14	-	28162770	SKM1	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.6964708159381465	[43]	[11]	-9	hSpCas9	negative selection	10750825
34462094	34462117	14	+	28162770	SKM1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-2.9374789154419414	[168]	[38]	-9	hSpCas9	negative selection	10750826
34435226	34435249	14	+	28162770	SKM1	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	1.4617912679785858	[22]	[111]	9	hSpCas9	negative selection	10750827
34435267	34435290	14	+	28162770	SKM1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.3203418439954109	[100]	[142]	-3	hSpCas9	negative selection	10750828
34435275	34435298	14	-	28162770	SKM1	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.28335130212422294	[65]	[141]	2	hSpCas9	negative selection	10750829
34435293	34435316	14	-	28162770	SKM1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.3379941861765752	[80]	[180]	3	hSpCas9	negative selection	10750830
34462199	34462222	14	-	28162770	PL21	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.58185973329139	[140]	[40]	-4	hSpCas9	negative selection	10920187
34462163	34462186	14	-	28162770	PL21	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.7442830376157998	[330]	[42]	-8	hSpCas9	negative selection	10920188
34462102	34462125	14	-	28162770	PL21	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.4580718682624745	[100]	[15]	-7	hSpCas9	negative selection	10920189
34462141	34462164	14	-	28162770	PL21	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-1.9804326311525005	[135]	[14]	-8	hSpCas9	negative selection	10920190
34462120	34462143	14	-	28162770	PL21	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-4.315560223794723	[182]	[3]	-9	hSpCas9	negative selection	10920191
34462094	34462117	14	+	28162770	PL21	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.690168096923594	[518]	[139]	-5	hSpCas9	negative selection	10920192
34435226	34435249	14	+	28162770	PL21	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.500300103651772	[64]	[19]	-4	hSpCas9	negative selection	10920193
34435267	34435290	14	+	28162770	PL21	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.9697853869529922	[395]	[87]	-6	hSpCas9	negative selection	10920194
34435275	34435298	14	-	28162770	PL21	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-1.0014942466803305	[183]	[39]	-6	hSpCas9	negative selection	10920195
34435293	34435316	14	-	28162770	PL21	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.14636835804833936	[327]	[157]	1	hSpCas9	negative selection	10920196
34462199	34462222	14	-	28162770	P31FUJ	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.0688534954467227	[128]	[158]	0	hSpCas9	negative selection	11089553
34462163	34462186	14	-	28162770	P31FUJ	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.36900658801269	[443]	[100]	-8	hSpCas9	negative selection	11089554
34462102	34462125	14	-	28162770	P31FUJ	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-4.8533886148662555	[122]	[4]	-9	hSpCas9	negative selection	11089555
34462141	34462164	14	-	28162770	P31FUJ	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.9697677985805846	[74]	[44]	-6	hSpCas9	negative selection	11089556
34462120	34462143	14	-	28162770	P31FUJ	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.127092763243264	[170]	[45]	-8	hSpCas9	negative selection	11089557
34462094	34462117	14	+	28162770	P31FUJ	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-2.969767798580585	[439]	[65]	-9	hSpCas9	negative selection	11089558
34435226	34435249	14	+	28162770	P31FUJ	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.3816655903288615	[101]	[91]	-3	hSpCas9	negative selection	11089559
34435267	34435290	14	+	28162770	P31FUJ	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.6647031413268728	[544]	[403]	-5	hSpCas9	negative selection	11089560
34435275	34435298	14	-	28162770	P31FUJ	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.2865734608553593	[245]	[236]	-3	hSpCas9	negative selection	11089561
34435293	34435316	14	-	28162770	P31FUJ	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.4754354181884512	[322]	[272]	-4	hSpCas9	negative selection	11089562
34462199	34462222	14	-	28162770	OCIAML5	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.7627992327669095	[93]	[99]	-5	hSpCas9	negative selection	11258919
34462163	34462186	14	-	28162770	OCIAML5	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.3127961608357097	[277]	[100]	-8	hSpCas9	negative selection	11258920
34462102	34462125	14	-	28162770	OCIAML5	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.9824632081196718	[80]	[73]	-6	hSpCas9	negative selection	11258921
34462141	34462164	14	-	28162770	OCIAML5	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	0.48897034697107	[29]	[75]	4	hSpCas9	negative selection	11258922
34462120	34462143	14	-	28162770	OCIAML5	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	0.34523486950962046	[57]	[132]	3	hSpCas9	negative selection	11258923
34462094	34462117	14	+	28162770	OCIAML5	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.20841576154956476	[280]	[438]	-1	hSpCas9	negative selection	11258924
34435226	34435249	14	+	28162770	OCIAML5	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	-0.6159992126304725	[44]	[52]	-4	hSpCas9	negative selection	11258925
34435267	34435290	14	+	28162770	OCIAML5	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.1589053296284193	[320]	[518]	-1	hSpCas9	negative selection	11258926
34435275	34435298	14	-	28162770	OCIAML5	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.017584470783528594	[142]	[254]	0	hSpCas9	negative selection	11258927
34435293	34435316	14	-	28162770	OCIAML5	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.30421724315994025	[209]	[306]	-2	hSpCas9	negative selection	11258928
34462199	34462222	14	-	28162770	EOL1	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.6489133289571072	[229]	[189]	6	hSpCas9	negative selection	11428285
34462163	34462186	14	-	28162770	EOL1	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.78100486996421	[423]	[64]	-8	hSpCas9	negative selection	11428286
34462102	34462125	14	-	28162770	EOL1	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-0.9884689268348255	[176]	[46]	-6	hSpCas9	negative selection	11428287
34462141	34462164	14	-	28162770	EOL1	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-3.162915069679805	[169]	[9]	-9	hSpCas9	negative selection	11428288
34462120	34462143	14	-	28162770	EOL1	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.7014419974106767	[320]	[25]	-9	hSpCas9	negative selection	11428289
34462094	34462117	14	+	28162770	EOL1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-1.158441593100497	[965]	[227]	-6	hSpCas9	negative selection	11428290
34435226	34435249	14	+	28162770	EOL1	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.24361621231865627	[100]	[62]	2	hSpCas9	negative selection	11428291
34435267	34435290	14	+	28162770	EOL1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.21617725342320326	[537]	[243]	-2	hSpCas9	negative selection	11428292
34435275	34435298	14	-	28162770	EOL1	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.7828113605103483	[208]	[63]	-5	hSpCas9	negative selection	11428293
34435293	34435316	14	-	28162770	EOL1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.01717874948079884	[376]	[200]	0	hSpCas9	negative selection	11428294
34462199	34462222	14	-	28162770	MOLM13	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.48391949136352774	[178]	[180]	3	hSpCas9	negative selection	11597651
34462163	34462186	14	-	28162770	MOLM13	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.0394522220541034	[397]	[69]	-7	hSpCas9	negative selection	11597652
34462102	34462125	14	-	28162770	MOLM13	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.0430725377328007	[113]	[39]	-5	hSpCas9	negative selection	11597653
34462141	34462164	14	-	28162770	MOLM13	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.6289721577080104	[153]	[71]	-4	hSpCas9	negative selection	11597654
34462120	34462143	14	-	28162770	MOLM13	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-3.1435453305377683	[219]	[17]	-8	hSpCas9	negative selection	11597655
34462094	34462117	14	+	28162770	MOLM13	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-1.9558693884369467	[718]	[133]	-7	hSpCas9	negative selection	11597656
34435226	34435249	14	+	28162770	MOLM13	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.5833665989645147	[107]	[116]	4	hSpCas9	negative selection	11597657
34435267	34435290	14	+	28162770	MOLM13	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.4079969221838409	[678]	[184]	-6	hSpCas9	negative selection	11597658
34435275	34435298	14	-	28162770	MOLM13	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.9491959463831234	[234]	[87]	-5	hSpCas9	negative selection	11597659
34435293	34435316	14	-	28162770	MOLM13	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.31095285277061224	[500]	[291]	-2	hSpCas9	negative selection	11597660
34462199	34462222	14	-	28162770	HEL	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.7523633231748552	[151]	[163]	6	hSpCas9	negative selection	11767017
34462163	34462186	14	-	28162770	HEL	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.1288993398206286	[378]	[110]	-6	hSpCas9	negative selection	11767018
34462102	34462125	14	-	28162770	HEL	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.1465821672269856	[158]	[45]	-6	hSpCas9	negative selection	11767019
34462141	34462164	14	-	28162770	HEL	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.21639863215979338	[155]	[85]	-1	hSpCas9	negative selection	11767020
34462120	34462143	14	-	28162770	HEL	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.4202709655254435	[233]	[111]	-3	hSpCas9	negative selection	11767021
34462094	34462117	14	+	28162770	HEL	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.010992900944035489	[622]	[395]	0	hSpCas9	negative selection	11767022
34435226	34435249	14	+	28162770	HEL	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.15293356431954108	[65]	[46]	1	hSpCas9	negative selection	11767023
34435267	34435290	14	+	28162770	HEL	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.29117197754187074	[511]	[267]	-2	hSpCas9	negative selection	11767024
34435275	34435298	14	-	28162770	HEL	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.33829816384183586	[204]	[165]	3	hSpCas9	negative selection	11767025
34435293	34435316	14	-	28162770	HEL	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.5096987427131141	[368]	[165]	-3	hSpCas9	negative selection	11767026
34462199	34462222	14	-	28162770	MV411	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.5115543497134296	[175]	[103]	-4	hSpCas9	negative selection	11936383
34462163	34462186	14	-	28162770	MV411	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.980831436890342	[327]	[69]	-8	hSpCas9	negative selection	11936384
34462102	34462125	14	-	28162770	MV411	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-4.590505691108252	[142]	[4]	-9	hSpCas9	negative selection	11936385
34462141	34462164	14	-	28162770	MV411	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-3.9852232060074995	[93]	[4]	-9	hSpCas9	negative selection	11936386
34462120	34462143	14	-	28162770	MV411	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-0.4306343543298624	[159]	[99]	-3	hSpCas9	negative selection	11936387
34462094	34462117	14	+	28162770	MV411	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-2.8467448882739324	[537]	[62]	-9	hSpCas9	negative selection	11936388
34435226	34435249	14	+	28162770	MV411	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	1.9789487148568734	[52]	[175]	9	hSpCas9	negative selection	11936389
34435267	34435290	14	+	28162770	MV411	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.7856207377965202	[308]	[150]	-5	hSpCas9	negative selection	11936390
34435275	34435298	14	-	28162770	MV411	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.9844031449489814	[203]	[339]	8	hSpCas9	negative selection	11936391
34435293	34435316	14	-	28162770	MV411	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.31085699947630097	[267]	[181]	-2	hSpCas9	negative selection	11936392
34462199	34462222	14	-	28162770	MONOMAC1	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.5150069283782328	[90]	[72]	-4	hSpCas9	negative selection	12105749
34462163	34462186	14	-	28162770	MONOMAC1	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-0.43632779296936997	[228]	[193]	-4	hSpCas9	negative selection	12105750
34462102	34462125	14	-	28162770	MONOMAC1	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-1.0901216431430418	[51]	[27]	-7	hSpCas9	negative selection	12105751
34462141	34462164	14	-	28162770	MONOMAC1	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-1.5826905395573032	[80]	[30]	-8	hSpCas9	negative selection	12105752
34462120	34462143	14	-	28162770	MONOMAC1	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.090121643143042	[103]	[27]	-9	hSpCas9	negative selection	12105753
34462094	34462117	14	+	28162770	MONOMAC1	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-0.4467568996124667	[301]	[253]	-4	hSpCas9	negative selection	12105754
34435226	34435249	14	+	28162770	MONOMAC1	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	2.170938615347245	[36]	[190]	9	hSpCas9	negative selection	12105755
34435267	34435290	14	+	28162770	MONOMAC1	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-1.2582007097379493	[264]	[126]	-7	hSpCas9	negative selection	12105756
34435275	34435298	14	-	28162770	MONOMAC1	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.8027579079475071	[139]	[91]	-6	hSpCas9	negative selection	12105757
34435293	34435316	14	-	28162770	MONOMAC1	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	0.522855233747711	[152]	[251]	5	hSpCas9	negative selection	12105758
34462199	34462222	14	-	28162770	OCIAML2	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	-0.20528525872116626	[25]	[124]	-2	hSpCas9	negative selection	12275115
34462163	34462186	14	-	28162770	OCIAML2	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-2.311932079223103	[42]	[47]	-8	hSpCas9	negative selection	12275116
34462102	34462125	14	-	28162770	OCIAML2	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-2.9112024166281425	[18]	[13]	-9	hSpCas9	negative selection	12275117
34462141	34462164	14	-	28162770	OCIAML2	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-0.8539584647936667	[14]	[45]	-5	hSpCas9	negative selection	12275118
34462120	34462143	14	-	28162770	OCIAML2	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.0763508861301148	[34]	[45]	-8	hSpCas9	negative selection	12275119
34462094	34462117	14	+	28162770	OCIAML2	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-1.216873232996378	[90]	[216]	-7	hSpCas9	negative selection	12275120
34435226	34435249	14	+	28162770	OCIAML2	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.11433267547899506	[11]	[71]	1	hSpCas9	negative selection	12275121
34435267	34435290	14	+	28162770	OCIAML2	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.30317307939059857	[64]	[291]	-2	hSpCas9	negative selection	12275122
34435275	34435298	14	-	28162770	OCIAML2	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	-0.5300083723210928	[30]	[118]	-4	hSpCas9	negative selection	12275123
34435293	34435316	14	-	28162770	OCIAML2	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-0.5961607073260202	[62]	[230]	-4	hSpCas9	negative selection	12275124
34462199	34462222	14	-	28162770	OCIAML3	viability	ATCGCGGGAGGCGCATGGCGGGG	SPTSSA	ENSG00000165389	0.9019498543382483	[38]	[219]	7	hSpCas9	negative selection	12444481
34462163	34462186	14	-	28162770	OCIAML3	viability	GGGCCTGGAAGCAGATGTCCTGG	SPTSSA	ENSG00000165389	-1.805511745517875	[87]	[75]	-8	hSpCas9	negative selection	12444482
34462102	34462125	14	-	28162770	OCIAML3	viability	GCTGGAGCCCTGGGAGCGGACGG	SPTSSA	ENSG00000165389	-6.500898235932682	[29]	[0]	-9	hSpCas9	negative selection	12444483
34462141	34462164	14	-	28162770	OCIAML3	viability	GTTCTACTACCAGTACCTGCTGG	SPTSSA	ENSG00000165389	-1.1789701410453195	[26]	[35]	-7	hSpCas9	negative selection	12444484
34462120	34462143	14	-	28162770	OCIAML3	viability	GGTCACGGCGCTCTACATGCTGG	SPTSSA	ENSG00000165389	-2.285885344961831	[62]	[38]	-9	hSpCas9	negative selection	12444485
34462094	34462117	14	+	28162770	OCIAML3	viability	ACTGAACACCGTCCGCTCCCAGG	SPTSSA	ENSG00000165389	-1.7018109298586783	[124]	[115]	-8	hSpCas9	negative selection	12444486
34435226	34435249	14	+	28162770	OCIAML3	viability	AATATCGCCATGATGTGCTGGGG	SPTSSA	ENSG00000165389	0.11381160818252667	[14]	[48]	1	hSpCas9	negative selection	12444487
34435267	34435290	14	+	28162770	OCIAML3	viability	GTATAGTGCCATCCCCACAATGG	SPTSSA	ENSG00000165389	-0.28385671321315464	[122]	[304]	-2	hSpCas9	negative selection	12444488
34435275	34435298	14	-	28162770	OCIAML3	viability	GCTGGTTTCCATTGTGGGGATGG	SPTSSA	ENSG00000165389	0.7340465573600408	[46]	[235]	6	hSpCas9	negative selection	12444489
34435293	34435316	14	-	28162770	OCIAML3	viability	CTACAACTCAGATTCCATGCTGG	SPTSSA	ENSG00000165389	-1.3416204786898778	[67]	[80]	-7	hSpCas9	negative selection	12444490