Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6721
• Symbol: SREBF2
• Description: sterol regulatory element binding transcription factor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/SREBF2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41866973	41866996	22	+	26472758	Jiyoye	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-2.4646682670034443	[182]	[24]	-9	hSpCas9	negative selection	156230
41833270	41833293	22	+	26472758	Jiyoye	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	-0.6135831786609239	[139]	[68]	-4	hSpCas9	negative selection	156231
41875568	41875591	22	+	26472758	Jiyoye	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-0.5777177261039184	[94]	[47]	-4	hSpCas9	negative selection	156232
41878009	41878032	22	-	26472758	Jiyoye	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.573715795546422	[74]	[37]	-4	hSpCas9	negative selection	156233
41884897	41884920	22	+	26472758	Jiyoye	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.22031173586183994	[240]	[155]	-1	hSpCas9	negative selection	156234
41884970	41884993	22	+	26472758	Jiyoye	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.9217485543356316	[34]	[49]	6	hSpCas9	negative selection	156235
41893178	41893201	22	-	26472758	Jiyoye	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.35181651899033184	[65]	[38]	-3	hSpCas9	negative selection	156236
41894842	41894865	22	-	26472758	Jiyoye	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	-0.8791288036507677	[99]	[40]	-6	hSpCas9	negative selection	156237
41900450	41900473	22	+	26472758	Jiyoye	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	1.441122713429211	[41]	[85]	8	hSpCas9	negative selection	156238
41900473	41900496	22	-	26472758	Jiyoye	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.893994153214692	[206]	[20]	-9	hSpCas9	negative selection	156239
41866973	41866996	22	+	26472758	KBM7	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-1.8002886591857596	[321,204]	[54,16]	-8	hSpCas9	negative selection	347348
41833270	41833293	22	+	26472758	KBM7	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.622837592123773	[387,354]	[314,227]	6	hSpCas9	negative selection	347349
41875568	41875591	22	+	26472758	KBM7	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.290567905548756	[288,174]	[220,49]	3	hSpCas9	negative selection	347350
41878009	41878032	22	-	26472758	KBM7	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.09636220428109843	[370,253]	[201,75]	-1	hSpCas9	negative selection	347351
41884897	41884920	22	+	26472758	KBM7	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.1810893651836849	[1064,859]	[438,358]	-2	hSpCas9	negative selection	347352
41884970	41884993	22	+	26472758	KBM7	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.42810130961668724	[105,132]	[60,90]	4	hSpCas9	negative selection	347353
41893178	41893201	22	-	26472758	KBM7	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.5964075232970171	[421,172]	[69,105]	-5	hSpCas9	negative selection	347354
41894842	41894865	22	-	26472758	KBM7	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.531274279716031	[320,196]	[133,206]	6	hSpCas9	negative selection	347355
41900450	41900473	22	+	26472758	KBM7	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	0.5527068324956288	[527,596]	[339,438]	6	hSpCas9	negative selection	347356
41900473	41900496	22	-	26472758	KBM7	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.472722893931399	[1056,1098]	[111,73]	-9	hSpCas9	negative selection	347357
41866973	41866996	22	+	26472758	Raji	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	0.38040202978001525	[95]	[28]	3	hSpCas9	negative selection	538466
41833270	41833293	22	+	26472758	Raji	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	-0.27304020882390745	[150]	[28]	-2	hSpCas9	negative selection	538467
41875568	41875591	22	+	26472758	Raji	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	1.043253197953884	[68]	[32]	8	hSpCas9	negative selection	538468
41878009	41878032	22	-	26472758	Raji	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.7170449000429461	[169]	[23]	-5	hSpCas9	negative selection	538469
41884897	41884920	22	+	26472758	Raji	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.027666424790253163	[469]	[106]	0	hSpCas9	negative selection	538470
41884970	41884993	22	+	26472758	Raji	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-0.40718963745615877	[119]	[20]	-3	hSpCas9	negative selection	538471
41893178	41893201	22	-	26472758	Raji	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.9906485475869274	[136]	[15]	-6	hSpCas9	negative selection	538472
41894842	41894865	22	-	26472758	Raji	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.1971802057242451	[108]	[28]	1	hSpCas9	negative selection	538473
41900450	41900473	22	+	26472758	Raji	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	0.01992069412326014	[152]	[35]	0	hSpCas9	negative selection	538474
41900473	41900496	22	-	26472758	Raji	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.6739761781510603	[494]	[17]	-9	hSpCas9	negative selection	538475
41866973	41866996	22	+	26472758	K562	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-4.0934509110899375	[181]	[8]	-9	hSpCas9	negative selection	729584
41833270	41833293	22	+	26472758	K562	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.1137688749575746	[230]	[210]	0	hSpCas9	negative selection	729585
41875568	41875591	22	+	26472758	K562	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.6406463771705324	[192]	[253]	5	hSpCas9	negative selection	729586
41878009	41878032	22	-	26472758	K562	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.12515473945602396	[176]	[136]	-1	hSpCas9	negative selection	729587
41884897	41884920	22	+	26472758	K562	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.07768852107906588	[732]	[652]	0	hSpCas9	negative selection	729588
41884970	41884993	22	+	26472758	K562	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	1.2613585900881592	[126]	[256]	9	hSpCas9	negative selection	729589
41893178	41893201	22	-	26472758	K562	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-2.9255062737758655	[161]	[17]	-8	hSpCas9	negative selection	729590
41894842	41894865	22	-	26472758	K562	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.803479364944846	[280]	[413]	6	hSpCas9	negative selection	729591
41900450	41900473	22	+	26472758	K562	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	1.5565476830284104	[324]	[806]	9	hSpCas9	negative selection	729592
41900473	41900496	22	-	26472758	K562	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-7.274431101041245	[916]	[4]	-9	hSpCas9	negative selection	729593
41833252	41833275	22	+	26627737	DLD1	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-1.065640487720252	[774]	[165,121,66]	-7	hSpCas9	negative selection	818068
41867209	41867232	22	+	26627737	DLD1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.9756683460888389	[602]	[155,109,31]	-7	hSpCas9	negative selection	818069
41868726	41868749	22	+	26627737	DLD1	viability	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.1113031546136774	[505]	[97,130,266]	1	hSpCas9	negative selection	818070
41870885	41870908	22	-	26627737	DLD1	viability	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.5144704253526258	[474]	[74,138,99]	-5	hSpCas9	negative selection	818071
41873782	41873805	22	+	26627737	DLD1	viability	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-2.0478821779001537	[721]	[32,66,62]	-9	hSpCas9	negative selection	818072
41875393	41875416	22	+	26627737	DLD1	viability	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-0.405608597586256	[157]	[43,61,10]	-4	hSpCas9	negative selection	818073
41833252	41833275	22	+	26627737	GBM cells	viability after 5 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.6472790556708954	[256]	[97,77]	-8	hSpCas9	negative selection	900383
41867209	41867232	22	+	26627737	GBM cells	viability after 5 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.13250450282699755	[164]	[104,88]	2	hSpCas9	negative selection	900384
41868726	41868749	22	+	26627737	GBM cells	viability after 5 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.27604338558834235	[240]	[127,184]	4	hSpCas9	negative selection	900385
41870885	41870908	22	-	26627737	GBM cells	viability after 5 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.9299742087215598	[269]	[74,76]	-8	hSpCas9	negative selection	900386
41873782	41873805	22	+	26627737	GBM cells	viability after 5 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.3432418012721923	[342]	[135,153]	-5	hSpCas9	negative selection	900387
41875393	41875416	22	+	26627737	GBM cells	viability after 5 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.9124604067236333	[52]	[63,42]	9	hSpCas9	negative selection	900388
41833252	41833275	22	+	26627737	GBM cells	viability after 13 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.36157916591801187	[256]	[134,86]	-4	hSpCas9	negative selection	982698
41867209	41867232	22	+	26627737	GBM cells	viability after 13 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.2511634072850166	[164]	[29,111]	-3	hSpCas9	negative selection	982699
41868726	41868749	22	+	26627737	GBM cells	viability after 13 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.6782469034201847	[240]	[211,206]	8	hSpCas9	negative selection	982700
41870885	41870908	22	-	26627737	GBM cells	viability after 13 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.7875696990515019	[269]	[96,74]	-7	hSpCas9	negative selection	982701
41873782	41873805	22	+	26627737	GBM cells	viability after 13 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.4403044235704183	[342]	[97,168]	-5	hSpCas9	negative selection	982702
41875393	41875416	22	+	26627737	GBM cells	viability after 13 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-0.06870709046144974	[52]	[38,17]	-1	hSpCas9	negative selection	982703
41833252	41833275	22	+	26627737	GBM cells	viability after 21 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.337042857220601	[256]	[202,151]	3	hSpCas9	negative selection	1065013
41867209	41867232	22	+	26627737	GBM cells	viability after 21 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.5996048337671261	[164]	[127,142]	6	hSpCas9	negative selection	1065014
41868726	41868749	22	+	26627737	GBM cells	viability after 21 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.6443979837022873	[240]	[200,207]	6	hSpCas9	negative selection	1065015
41870885	41870908	22	-	26627737	GBM cells	viability after 21 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-1.4027442024347545	[269]	[55,54]	-8	hSpCas9	negative selection	1065016
41873782	41873805	22	+	26627737	GBM cells	viability after 21 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.6549832949226069	[342]	[121,114]	-5	hSpCas9	negative selection	1065017
41875393	41875416	22	+	26627737	GBM cells	viability after 21 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-2.3824382097149295	[52]	[4,5]	-9	hSpCas9	negative selection	1065018
41833252	41833275	22	+	26627737	RPE1	viability after 9 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.018490471601896694	[833]	[176,361]	0	hSpCas9	negative selection	1147328
41867209	41867232	22	+	26627737	RPE1	viability after 9 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.005135705107408524	[751]	[213,264]	0	hSpCas9	negative selection	1147329
41868726	41868749	22	+	26627737	RPE1	viability after 9 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.3700652330893336	[546]	[133,333]	2	hSpCas9	negative selection	1147330
41870885	41870908	22	-	26627737	RPE1	viability after 9 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-1.0328225023456328	[984]	[165,130]	-6	hSpCas9	negative selection	1147331
41873782	41873805	22	+	26627737	RPE1	viability after 9 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	0.1310370850987549	[456]	[119,203]	0	hSpCas9	negative selection	1147332
41875393	41875416	22	+	26627737	RPE1	viability after 9 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	8.17966405405915	[0]	[40,154]	9	hSpCas9	negative selection	1147333
41833252	41833275	22	+	26627737	RPE1	viability after 12 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.3310281568944287	[833]	[293,268]	2	hSpCas9	negative selection	1229643
41867209	41867232	22	+	26627737	RPE1	viability after 12 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.1722414751186149	[751]	[147,311]	1	hSpCas9	negative selection	1229644
41868726	41868749	22	+	26627737	RPE1	viability after 12 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.3098672859260866	[546]	[153,211]	2	hSpCas9	negative selection	1229645
41870885	41870908	22	-	26627737	RPE1	viability after 12 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-1.9555643983507625	[984]	[109,23]	-8	hSpCas9	negative selection	1229646
41873782	41873805	22	+	26627737	RPE1	viability after 12 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	0.16409812240092347	[456]	[88,188]	1	hSpCas9	negative selection	1229647
41875393	41875416	22	+	26627737	RPE1	viability after 12 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	8.608392742458747	[0]	[99,109]	9	hSpCas9	negative selection	1229648
41833252	41833275	22	+	26627737	RPE1	viability after 15 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.770373973861117	[833]	[322,478]	5	hSpCas9	negative selection	1311958
41867209	41867232	22	+	26627737	RPE1	viability after 15 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.01263828585475086	[751]	[161,257]	0	hSpCas9	negative selection	1311959
41868726	41868749	22	+	26627737	RPE1	viability after 15 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.13241734133402494	[546]	[50,283]	0	hSpCas9	negative selection	1311960
41870885	41870908	22	-	26627737	RPE1	viability after 15 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-1.9110584749879425	[984]	[40,105]	-8	hSpCas9	negative selection	1311961
41873782	41873805	22	+	26627737	RPE1	viability after 15 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	0.5666775056164834	[456]	[164,216]	3	hSpCas9	negative selection	1311962
41875393	41875416	22	+	26627737	RPE1	viability after 15 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	7.9876789966257435	[0]	[82,60]	9	hSpCas9	negative selection	1311963
41833252	41833275	22	+	26627737	RPE1	viability after 18 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.08376781033467898	[833]	[180,299]	0	hSpCas9	negative selection	1394273
41867209	41867232	22	+	26627737	RPE1	viability after 18 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.10053245539164293	[751]	[190,245]	0	hSpCas9	negative selection	1394274
41868726	41868749	22	+	26627737	RPE1	viability after 18 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.14396385802406164	[546]	[107,221]	0	hSpCas9	negative selection	1394275
41870885	41870908	22	-	26627737	RPE1	viability after 18 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-2.4905867427255584	[984]	[55,37]	-8	hSpCas9	negative selection	1394276
41873782	41873805	22	+	26627737	RPE1	viability after 18 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.6073764647064794	[456]	[64,97]	-4	hSpCas9	negative selection	1394277
41875393	41875416	22	+	26627737	RPE1	viability after 18 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	7.611771648690569	[0]	[31,74]	9	hSpCas9	negative selection	1394278
41833252	41833275	22	+	26627737	HeLa	viability after 8 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.27415693158759075	[244]	[126,80,174]	2	hSpCas9	negative selection	1476588
41867209	41867232	22	+	26627737	HeLa	viability after 8 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.36244515118083453	[259]	[86,183,151]	3	hSpCas9	negative selection	1476589
41868726	41868749	22	+	26627737	HeLa	viability after 8 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-0.7408389361395022	[735]	[150,119,287]	-6	hSpCas9	negative selection	1476590
41870885	41870908	22	-	26627737	HeLa	viability after 8 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.03748095579945504	[439]	[212,158,192]	0	hSpCas9	negative selection	1476591
41873782	41873805	22	+	26627737	HeLa	viability after 8 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	0.03863130029434275	[477]	[270,234,151]	0	hSpCas9	negative selection	1476592
41875393	41875416	22	+	26627737	HeLa	viability after 8 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.8371958452996695	[88]	[38,4,150]	7	hSpCas9	negative selection	1476593
41833252	41833275	22	+	26627737	HeLa	viability after 12 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.15469696543369316	[244]	[123,60,91]	-1	hSpCas9	negative selection	1558903
41867209	41867232	22	+	26627737	HeLa	viability after 12 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	1.0859688415682727	[259]	[229,268,180]	7	hSpCas9	negative selection	1558904
41868726	41868749	22	+	26627737	HeLa	viability after 12 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-2.342838123168285	[735]	[2,61,112]	-9	hSpCas9	negative selection	1558905
41870885	41870908	22	-	26627737	HeLa	viability after 12 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.1908754529105063	[439]	[366,134,132]	1	hSpCas9	negative selection	1558906
41873782	41873805	22	+	26627737	HeLa	viability after 12 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.1119791986999065	[477]	[260,84,214]	-1	hSpCas9	negative selection	1558907
41875393	41875416	22	+	26627737	HeLa	viability after 12 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	1.6196066989441342	[88]	[153,39,153]	9	hSpCas9	negative selection	1558908
41833252	41833275	22	+	26627737	HeLa	viability after 15 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.11094994437017047	[244]	[124,42,109]	-1	hSpCas9	negative selection	1641218
41867209	41867232	22	+	26627737	HeLa	viability after 15 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.6421793059697728	[259]	[188,240,56]	5	hSpCas9	negative selection	1641219
41868726	41868749	22	+	26627737	HeLa	viability after 15 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-0.8346498255663629	[735]	[46,200,264]	-6	hSpCas9	negative selection	1641220
41870885	41870908	22	-	26627737	HeLa	viability after 15 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.22799518396113855	[439]	[222,80,153]	-2	hSpCas9	negative selection	1641221
41873782	41873805	22	+	26627737	HeLa	viability after 15 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.2002131456705294	[477]	[115,160,236]	-2	hSpCas9	negative selection	1641222
41875393	41875416	22	+	26627737	HeLa	viability after 15 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.13714665362897538	[88]	[23,88,3]	1	hSpCas9	negative selection	1641223
41833252	41833275	22	+	26627737	HeLa	viability after 18 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.15792301751280446	[244]	[80,31,109]	-1	hSpCas9	negative selection	1723533
41867209	41867232	22	+	26627737	HeLa	viability after 18 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.6721442383437377	[259]	[133,198,56]	5	hSpCas9	negative selection	1723534
41868726	41868749	22	+	26627737	HeLa	viability after 18 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-0.8253297520990099	[735]	[29,170,264]	-6	hSpCas9	negative selection	1723535
41870885	41870908	22	-	26627737	HeLa	viability after 18 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.22548463760995524	[439]	[154,60,153]	-2	hSpCas9	negative selection	1723536
41873782	41873805	22	+	26627737	HeLa	viability after 18 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.18056373282204333	[477]	[80,134,236]	-1	hSpCas9	negative selection	1723537
41875393	41875416	22	+	26627737	HeLa	viability after 18 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.16920165655642427	[88]	[15,75,3]	1	hSpCas9	negative selection	1723538
41833252	41833275	22	+	26627737	HCT116	viability after 6 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.42302272768728527	[371]	[31,103]	2	hSpCas9	negative selection	1805848
41867209	41867232	22	+	26627737	HCT116	viability after 6 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.3509182345034156	[576]	[261,34]	2	hSpCas9	negative selection	1805849
41868726	41868749	22	+	26627737	HCT116	viability after 6 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	4.142803409663622	[171]	[583,418]	9	hSpCas9	negative selection	1805850
41870885	41870908	22	-	26627737	HCT116	viability after 6 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.1313457000584847	[752]	[187,63]	0	hSpCas9	negative selection	1805851
41873782	41873805	22	+	26627737	HCT116	viability after 6 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.008887560105748316	[1242]	[141,222]	0	hSpCas9	negative selection	1805852
41875393	41875416	22	+	26627737	HCT116	viability after 6 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	3.0952320695384676	[37]	[139,1]	9	hSpCas9	negative selection	1805853
41833252	41833275	22	+	26627737	HCT116	viability after 8 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.09689638535843861	[349]	[166,238,211]	1	hSpCas9	negative selection	1888163
41867209	41867232	22	+	26627737	HCT116	viability after 8 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.2921573678648515	[302]	[193,203,214]	3	hSpCas9	negative selection	1888164
41868726	41868749	22	+	26627737	HCT116	viability after 8 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.9343211732590554	[167]	[217,181,131]	8	hSpCas9	negative selection	1888165
41870885	41870908	22	-	26627737	HCT116	viability after 8 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.4076239132076885	[302]	[142,116,117]	-5	hSpCas9	negative selection	1888166
41873782	41873805	22	+	26627737	HCT116	viability after 8 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.023185179256234423	[444]	[276,244,202]	0	hSpCas9	negative selection	1888167
41875393	41875416	22	+	26627737	HCT116	viability after 8 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.57478064908779	[98]	[102,47,92]	6	hSpCas9	negative selection	1888168
41833252	41833275	22	+	26627737	HCT116	viability after 9 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	1.7428265224645916	[371]	[475,218]	9	hSpCas9	negative selection	1970478
41867209	41867232	22	+	26627737	HCT116	viability after 9 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.21797462394300138	[576]	[38,289]	1	hSpCas9	negative selection	1970479
41868726	41868749	22	+	26627737	HCT116	viability after 9 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	1.6779552503178612	[171]	[51,221]	8	hSpCas9	negative selection	1970480
41870885	41870908	22	-	26627737	HCT116	viability after 9 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.1623372812871101	[752]	[220,146]	-1	hSpCas9	negative selection	1970481
41873782	41873805	22	+	26627737	HCT116	viability after 9 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	0.09445264950474797	[1242]	[183,488]	0	hSpCas9	negative selection	1970482
41875393	41875416	22	+	26627737	HCT116	viability after 9 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	1.142837223776683	[37]	[8,32]	7	hSpCas9	negative selection	1970483
41833252	41833275	22	+	26627737	HCT116	viability after 12 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.23847562321821394	[349]	[179,165,306]	2	hSpCas9	negative selection	2052793
41867209	41867232	22	+	26627737	HCT116	viability after 12 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.43143029307279324	[302]	[218,179,243]	4	hSpCas9	negative selection	2052794
41868726	41868749	22	+	26627737	HCT116	viability after 12 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.33718878908998834	[167]	[112,91,128]	3	hSpCas9	negative selection	2052795
41870885	41870908	22	-	26627737	HCT116	viability after 12 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.1603014125831545	[302]	[182,104,134]	-2	hSpCas9	negative selection	2052796
41873782	41873805	22	+	26627737	HCT116	viability after 12 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.2871993924802935	[444]	[213,233,125]	-3	hSpCas9	negative selection	2052797
41875393	41875416	22	+	26627737	HCT116	viability after 12 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.12155913371044713	[98]	[99,56,8]	1	hSpCas9	negative selection	2052798
41833252	41833275	22	+	26627737	HCT116	viability after 15 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.18853309508415803	[349]	[81,287,147]	-2	hSpCas9	negative selection	2135108
41867209	41867232	22	+	26627737	HCT116	viability after 15 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.39779622290497507	[302]	[197,175,308]	4	hSpCas9	negative selection	2135109
41868726	41868749	22	+	26627737	HCT116	viability after 15 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.6355317471906028	[167]	[137,225,84]	6	hSpCas9	negative selection	2135110
41870885	41870908	22	-	26627737	HCT116	viability after 15 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.22863637993107222	[302]	[194,161,252]	2	hSpCas9	negative selection	2135111
41873782	41873805	22	+	26627737	HCT116	viability after 15 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.20435899052233591	[444]	[241,213,211]	-2	hSpCas9	negative selection	2135112
41875393	41875416	22	+	26627737	HCT116	viability after 15 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.43533115074826	[98]	[111,52,69]	4	hSpCas9	negative selection	2135113
41833252	41833275	22	+	26627737	HCT116	viability after 18 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.20801622594146843	[349]	[212,216,152]	1	hSpCas9	negative selection	2217423
41867209	41867232	22	+	26627737	HCT116	viability after 18 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.5578571095014968	[302]	[197,127,331]	5	hSpCas9	negative selection	2217424
41868726	41868749	22	+	26627737	HCT116	viability after 18 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	1.2685287863605492	[167]	[309,165,108]	8	hSpCas9	negative selection	2217425
41870885	41870908	22	-	26627737	HCT116	viability after 18 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.5530639196413801	[302]	[283,235,118]	4	hSpCas9	negative selection	2217426
41873782	41873805	22	+	26627737	HCT116	viability after 18 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.2278021709647487	[444]	[240,109,205]	-2	hSpCas9	negative selection	2217427
41875393	41875416	22	+	26627737	HCT116	viability after 18 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-0.9869257709269916	[98]	[45,18,6]	-7	hSpCas9	negative selection	2217428
41833262	41833285	22	+	24336569	HL60	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.5589021652915949	[595]	[1857]	5	hSpCas9	negative selection	2297243
41833270	41833293	22	+	24336569	HL60	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.11959019036488128	[865]	[1990]	1	hSpCas9	negative selection	2297244
41833279	41833302	22	+	24336569	HL60	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-0.621179976476697	[768]	[1057]	-5	hSpCas9	negative selection	2297245
41833288	41833311	22	+	24336569	HL60	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-0.6073083857936747	[256]	[356]	-5	hSpCas9	negative selection	2297246
41833300	41833323	22	+	24336569	HL60	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	1.3680349827971408	[105]	[578]	8	hSpCas9	negative selection	2297247
41833305	41833328	22	-	24336569	HL60	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	-0.1071507442925459	[169]	[333]	-1	hSpCas9	negative selection	2297248
41833314	41833337	22	-	24336569	HL60	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-0.6695459431942314	[462]	[615]	-6	hSpCas9	negative selection	2297249
41833324	41833347	22	+	24336569	HL60	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	-0.1619441475971663	[598]	[1132]	-1	hSpCas9	negative selection	2297250
41833337	41833360	22	+	24336569	HL60	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	-0.7399794685931657	[1186]	[1503]	-6	hSpCas9	negative selection	2297251
41833342	41833365	22	-	24336569	HL60	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	-0.4829973355579925	[637]	[965]	-4	hSpCas9	negative selection	2297252
41833262	41833285	22	+	24336569	KBM7	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.04975040397897901	[706]	[1995]	0	hSpCas9	negative selection	2364420
41833270	41833293	22	+	24336569	KBM7	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.12768190297997983	[944]	[2815]	1	hSpCas9	negative selection	2364421
41833279	41833302	22	+	24336569	KBM7	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	1.2862971136940833	[373]	[2487]	9	hSpCas9	negative selection	2364422
41833288	41833311	22	+	24336569	KBM7	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-1.0325416972700387	[308]	[411]	-6	hSpCas9	negative selection	2364423
41833300	41833323	22	+	24336569	KBM7	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	-2.988147577911586	[191]	[65]	-9	hSpCas9	negative selection	2364424
41833305	41833328	22	-	24336569	KBM7	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	0.5464959694940122	[182]	[728]	5	hSpCas9	negative selection	2364425
41833314	41833337	22	-	24336569	KBM7	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-0.11113532200083301	[355]	[898]	-1	hSpCas9	negative selection	2364426
41833324	41833347	22	+	24336569	KBM7	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	-0.23812583091993272	[639]	[1479]	-2	hSpCas9	negative selection	2364427
41833337	41833360	22	+	24336569	KBM7	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	0.29916496300745044	[1190]	[3996]	2	hSpCas9	negative selection	2364428
41833342	41833365	22	-	24336569	KBM7	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	0.9392506005914472	[438]	[2295]	7	hSpCas9	negative selection	2364429
41851725	41851748	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGGCGGGTGGATCACCTGCAG	SREBF2	ENSG00000198911	4.518200288702036	[0,0]	[6,3]	9	dCas9-VP64	positive selection	2405062
41874811	41874834	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATTGTTTGAACCTGG	SREBF2	ENSG00000198911	0.964443282063522	[91,283]	[89,70]	4	dCas9-VP64	positive selection	2426728
41890805	41890828	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGAGGCAGGAGAATTGCTAG	SREBF2	ENSG00000198911	1.7637175755419017	[20,19]	[24,4]	6	dCas9-VP64	positive selection	2454687
41854360	41854383	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACATGG	SREBF2	ENSG00000198911	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458979
41867689	41867712	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGAGG	SREBF2	ENSG00000198911	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465873
41851725	41851748	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGGCGGGTGGATCACCTGCAG	SREBF2	ENSG00000198911	0.16369270891915377	[4,8]	[2,0]	1	dCas9-VP64	positive selection	2500317
41874811	41874834	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATTGTTTGAACCTGG	SREBF2	ENSG00000198911	-0.320288383300443	[193,176]	[58,37]	-3	dCas9-VP64	positive selection	2521983
41890805	41890828	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGAGGCAGGAGAATTGCTAG	SREBF2	ENSG00000198911	-0.8253509621016023	[144,7]	[19,7]	-7	dCas9-VP64	positive selection	2549942
41854360	41854383	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACATGG	SREBF2	ENSG00000198911	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554234
41867689	41867712	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGAGG	SREBF2	ENSG00000198911	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561128
41833314	41833337	22	-	27260157	DLD1	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-0.209348795498291	[]	[]	-1	hSpCas9	negative selection	2575039
41868719	41868742	22	-	27260157	DLD1	viability	AAGGGTCTGCAGCGTGCCATTGG	SREBF2	ENSG00000198911	0.900303769885504	[]	[]	9	hSpCas9	negative selection	2576995
41833315	41833338	22	-	27260157	DLD1	viability	GCTCGTCGCCCAGCTCCGTGAGG	SREBF2	ENSG00000198911	1.25058594741296	[]	[]	9	hSpCas9	negative selection	2577845
41867209	41867232	22	+	27260157	DLD1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.231947662920729	[]	[]	-2	hSpCas9	negative selection	2578083
41868695	41868718	22	-	27260157	DLD1	viability	CGTTTGTGTCAGCACCCGCTGGG	SREBF2	ENSG00000198911	-0.215793242464223	[]	[]	-2	hSpCas9	negative selection	2582678
41833288	41833311	22	+	27260157	DLD1	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-1.20256583008968	[]	[]	-7	hSpCas9	negative selection	2583812
41867003	41867026	22	+	27260157	DLD1	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.434248614609926	[]	[]	-4	hSpCas9	negative selection	2584922
41833264	41833287	22	-	27260157	DLD1	viability	CGCCGCTGTCGTCCATCGCCCGG	SREBF2	ENSG00000198911	-3.68633174959506	[]	[]	-9	hSpCas9	negative selection	2605742
41833337	41833360	22	+	27260157	DLD1	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	0.529559738115664	[]	[]	8	hSpCas9	negative selection	2607128
41833300	41833323	22	+	27260157	DLD1	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	1.37242263551228	[]	[]	9	hSpCas9	negative selection	2608628
41833252	41833275	22	+	27260157	DLD1	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.0469726111982057	[]	[]	3	hSpCas9	negative selection	2609728
41867215	41867238	22	-	27260157	DLD1	viability	GATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.475882297056626	[]	[]	8	hSpCas9	negative selection	2614484
41833305	41833328	22	-	27260157	DLD1	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	0.723480416933695	[]	[]	8	hSpCas9	negative selection	2614896
41833279	41833302	22	+	27260157	DLD1	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-0.686180478170134	[]	[]	-5	hSpCas9	negative selection	2616011
41833324	41833347	22	+	27260157	DLD1	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	0.657927911757752	[]	[]	8	hSpCas9	negative selection	2619020
41833274	41833297	22	+	27260157	DLD1	viability	GACGACAGCGGCGAGCTGGGTGG	SREBF2	ENSG00000198911	0.187632591266281	[]	[]	3	hSpCas9	negative selection	2619272
41833262	41833285	22	+	27260157	DLD1	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.817417615098862	[]	[]	9	hSpCas9	negative selection	2622865
41866997	41867020	22	-	27260157	DLD1	viability	TGAATGACCGTTGCACTGAAGGG	SREBF2	ENSG00000198911	-0.205830577436029	[]	[]	-1	hSpCas9	negative selection	2623453
41833270	41833293	22	+	27260157	DLD1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.212035628521614	[]	[]	3	hSpCas9	negative selection	2645803
41833342	41833365	22	-	27260157	DLD1	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	-0.208350344140157	[]	[]	-1	hSpCas9	negative selection	2647532
41833314	41833337	22	-	27260157	HT1080	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-1.07378848424192	[]	[]	-8	hSpCas9	negative selection	2651169
41868719	41868742	22	-	27260157	HT1080	viability	AAGGGTCTGCAGCGTGCCATTGG	SREBF2	ENSG00000198911	0.657219704889979	[]	[]	6	hSpCas9	negative selection	2653125
41833315	41833338	22	-	27260157	HT1080	viability	GCTCGTCGCCCAGCTCCGTGAGG	SREBF2	ENSG00000198911	0.14267905693963	[]	[]	1	hSpCas9	negative selection	2653975
41867209	41867232	22	+	27260157	HT1080	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.482861074910352	[]	[]	-7	hSpCas9	negative selection	2654213
41868695	41868718	22	-	27260157	HT1080	viability	CGTTTGTGTCAGCACCCGCTGGG	SREBF2	ENSG00000198911	-1.41507771512712	[]	[]	-9	hSpCas9	negative selection	2658808
41833288	41833311	22	+	27260157	HT1080	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-0.748049369501677	[]	[]	-8	hSpCas9	negative selection	2659942
41867003	41867026	22	+	27260157	HT1080	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-1.20189018800588	[]	[]	-8	hSpCas9	negative selection	2661052
41833264	41833287	22	-	27260157	HT1080	viability	CGCCGCTGTCGTCCATCGCCCGG	SREBF2	ENSG00000198911	-2.00071372787164	[]	[]	-9	hSpCas9	negative selection	2681872
41833337	41833360	22	+	27260157	HT1080	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	-0.355627615132823	[]	[]	-7	hSpCas9	negative selection	2683258
41833300	41833323	22	+	27260157	HT1080	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	-1.48222179300608	[]	[]	-9	hSpCas9	negative selection	2684758
41833252	41833275	22	+	27260157	HT1080	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.700554835790513	[]	[]	-8	hSpCas9	negative selection	2685858
41867215	41867238	22	-	27260157	HT1080	viability	GATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	-1.86552542101691	[]	[]	-9	hSpCas9	negative selection	2690614
41833305	41833328	22	-	27260157	HT1080	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	-0.765418322564108	[]	[]	-8	hSpCas9	negative selection	2691026
41833279	41833302	22	+	27260157	HT1080	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-0.748759207404302	[]	[]	-8	hSpCas9	negative selection	2692141
41833324	41833347	22	+	27260157	HT1080	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	-0.822904868799664	[]	[]	-8	hSpCas9	negative selection	2695150
41833274	41833297	22	+	27260157	HT1080	viability	GACGACAGCGGCGAGCTGGGTGG	SREBF2	ENSG00000198911	-1.38468225907529	[]	[]	-9	hSpCas9	negative selection	2695402
41833262	41833285	22	+	27260157	HT1080	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.753942156348891	[]	[]	6	hSpCas9	negative selection	2698995
41866997	41867020	22	-	27260157	HT1080	viability	TGAATGACCGTTGCACTGAAGGG	SREBF2	ENSG00000198911	-0.400570430530545	[]	[]	-7	hSpCas9	negative selection	2699583
41833270	41833293	22	+	27260157	HT1080	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.618420688384907	[]	[]	5	hSpCas9	negative selection	2721933
41833342	41833365	22	-	27260157	HT1080	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	-2.09407230036054	[]	[]	-9	hSpCas9	negative selection	2723662
41833314	41833337	22	-	27260157	MKN45	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	0.733948768558966	[]	[]	7	hSpCas9	negative selection	2727299
41868719	41868742	22	-	27260157	MKN45	viability	AAGGGTCTGCAGCGTGCCATTGG	SREBF2	ENSG00000198911	1.00949169676311	[]	[]	8	hSpCas9	negative selection	2729255
41833315	41833338	22	-	27260157	MKN45	viability	GCTCGTCGCCCAGCTCCGTGAGG	SREBF2	ENSG00000198911	1.08768730682698	[]	[]	8	hSpCas9	negative selection	2730105
41867209	41867232	22	+	27260157	MKN45	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.455944972415222	[]	[]	-6	hSpCas9	negative selection	2730343
41868695	41868718	22	-	27260157	MKN45	viability	CGTTTGTGTCAGCACCCGCTGGG	SREBF2	ENSG00000198911	-0.185915306121279	[]	[]	0	hSpCas9	negative selection	2734938
41833288	41833311	22	+	27260157	MKN45	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	0.342735545041335	[]	[]	6	hSpCas9	negative selection	2736072
41867003	41867026	22	+	27260157	MKN45	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.450547960630048	[]	[]	6	hSpCas9	negative selection	2737182
41833264	41833287	22	-	27260157	MKN45	viability	CGCCGCTGTCGTCCATCGCCCGG	SREBF2	ENSG00000198911	-1.619347633628	[]	[]	-9	hSpCas9	negative selection	2758002
41833337	41833360	22	+	27260157	MKN45	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	1.67284362141092	[]	[]	9	hSpCas9	negative selection	2759388
41833300	41833323	22	+	27260157	MKN45	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	0.756902028821348	[]	[]	7	hSpCas9	negative selection	2760888
41833252	41833275	22	+	27260157	MKN45	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.275835885021916	[]	[]	5	hSpCas9	negative selection	2761988
41867215	41867238	22	-	27260157	MKN45	viability	GATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	1.56623145791909	[]	[]	9	hSpCas9	negative selection	2766744
41833305	41833328	22	-	27260157	MKN45	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	0.475561852487242	[]	[]	6	hSpCas9	negative selection	2767156
41833279	41833302	22	+	27260157	MKN45	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-1.03653620623599	[]	[]	-8	hSpCas9	negative selection	2768271
41833324	41833347	22	+	27260157	MKN45	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	0.46628530180095	[]	[]	6	hSpCas9	negative selection	2771280
41833274	41833297	22	+	27260157	MKN45	viability	GACGACAGCGGCGAGCTGGGTGG	SREBF2	ENSG00000198911	0.410053627876973	[]	[]	6	hSpCas9	negative selection	2771532
41833262	41833285	22	+	27260157	MKN45	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.847454813204342	[]	[]	8	hSpCas9	negative selection	2775125
41866997	41867020	22	-	27260157	MKN45	viability	TGAATGACCGTTGCACTGAAGGG	SREBF2	ENSG00000198911	0.44138142308625	[]	[]	6	hSpCas9	negative selection	2775713
41833270	41833293	22	+	27260157	MKN45	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	1.62620568913009	[]	[]	9	hSpCas9	negative selection	2798063
41833342	41833365	22	-	27260157	MKN45	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	-0.0510162069095201	[]	[]	0	hSpCas9	negative selection	2799792
41833314	41833337	22	-	27260157	RKO	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-0.319205084203644	[]	[]	-6	hSpCas9	negative selection	2803429
41868719	41868742	22	-	27260157	RKO	viability	AAGGGTCTGCAGCGTGCCATTGG	SREBF2	ENSG00000198911	0.296823921380503	[]	[]	1	hSpCas9	negative selection	2805385
41833315	41833338	22	-	27260157	RKO	viability	GCTCGTCGCCCAGCTCCGTGAGG	SREBF2	ENSG00000198911	0.159543562011843	[]	[]	0	hSpCas9	negative selection	2806235
41867209	41867232	22	+	27260157	RKO	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.362631185584254	[]	[]	-6	hSpCas9	negative selection	2806473
41868695	41868718	22	-	27260157	RKO	viability	CGTTTGTGTCAGCACCCGCTGGG	SREBF2	ENSG00000198911	-0.108992972505925	[]	[]	0	hSpCas9	negative selection	2811068
41833288	41833311	22	+	27260157	RKO	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-0.773520849863906	[]	[]	-7	hSpCas9	negative selection	2812202
41867003	41867026	22	+	27260157	RKO	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	1.06097826582041	[]	[]	9	hSpCas9	negative selection	2813312
41833264	41833287	22	-	27260157	RKO	viability	CGCCGCTGTCGTCCATCGCCCGG	SREBF2	ENSG00000198911	-1.45137445985591	[]	[]	-8	hSpCas9	negative selection	2834132
41833337	41833360	22	+	27260157	RKO	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	0.842120673001361	[]	[]	8	hSpCas9	negative selection	2835518
41833300	41833323	22	+	27260157	RKO	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	-0.936056423738505	[]	[]	-8	hSpCas9	negative selection	2837018
41833252	41833275	22	+	27260157	RKO	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.125158278797917	[]	[]	0	hSpCas9	negative selection	2838118
41867215	41867238	22	-	27260157	RKO	viability	GATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.506990480877002	[]	[]	2	hSpCas9	negative selection	2842874
41833305	41833328	22	-	27260157	RKO	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	0.346018861882743	[]	[]	1	hSpCas9	negative selection	2843286
41833279	41833302	22	+	27260157	RKO	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-0.441939062995451	[]	[]	-6	hSpCas9	negative selection	2844401
41833324	41833347	22	+	27260157	RKO	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	0.398142810188422	[]	[]	2	hSpCas9	negative selection	2847410
41833274	41833297	22	+	27260157	RKO	viability	GACGACAGCGGCGAGCTGGGTGG	SREBF2	ENSG00000198911	0.0551469244031141	[]	[]	0	hSpCas9	negative selection	2847662
41833262	41833285	22	+	27260157	RKO	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	0.0160219062857608	[]	[]	0	hSpCas9	negative selection	2851255
41866997	41867020	22	-	27260157	RKO	viability	TGAATGACCGTTGCACTGAAGGG	SREBF2	ENSG00000198911	0.207602336824271	[]	[]	1	hSpCas9	negative selection	2851843
41833270	41833293	22	+	27260157	RKO	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	1.32528677128271	[]	[]	9	hSpCas9	negative selection	2874193
41833342	41833365	22	-	27260157	RKO	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	0.284685221303409	[]	[]	1	hSpCas9	negative selection	2875922
41833314	41833337	22	-	27260157	SF268	viability	CTCGTCGCCCAGCTCCGTGAGGG	SREBF2	ENSG00000198911	-0.0964754660652858	[]	[]	0	hSpCas9	negative selection	2879559
41868719	41868742	22	-	27260157	SF268	viability	AAGGGTCTGCAGCGTGCCATTGG	SREBF2	ENSG00000198911	0.725671199429365	[]	[]	8	hSpCas9	negative selection	2881515
41833315	41833338	22	-	27260157	SF268	viability	GCTCGTCGCCCAGCTCCGTGAGG	SREBF2	ENSG00000198911	0.667520932576074	[]	[]	8	hSpCas9	negative selection	2882365
41867209	41867232	22	+	27260157	SF268	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.281581323376832	[]	[]	-2	hSpCas9	negative selection	2882603
41868695	41868718	22	-	27260157	SF268	viability	CGTTTGTGTCAGCACCCGCTGGG	SREBF2	ENSG00000198911	-0.0683502020707212	[]	[]	0	hSpCas9	negative selection	2887198
41833288	41833311	22	+	27260157	SF268	viability	GCTGGGTGGTCTGGAGACCATGG	SREBF2	ENSG00000198911	-0.549062489175142	[]	[]	-4	hSpCas9	negative selection	2888332
41867003	41867026	22	+	27260157	SF268	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.758690765158367	[]	[]	-6	hSpCas9	negative selection	2889442
41833264	41833287	22	-	27260157	SF268	viability	CGCCGCTGTCGTCCATCGCCCGG	SREBF2	ENSG00000198911	-1.83717557592846	[]	[]	-8	hSpCas9	negative selection	2910262
41833337	41833360	22	+	27260157	SF268	viability	CTGACCCTGGGAGACATCGACGG	SREBF2	ENSG00000198911	1.20674204525808	[]	[]	9	hSpCas9	negative selection	2911648
41833300	41833323	22	+	27260157	SF268	viability	GGAGACCATGGAGACCCTCACGG	SREBF2	ENSG00000198911	-0.248431632989169	[]	[]	-2	hSpCas9	negative selection	2913148
41833252	41833275	22	+	27260157	SF268	viability	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.0400135076158297	[]	[]	0	hSpCas9	negative selection	2914248
41867215	41867238	22	-	27260157	SF268	viability	GATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	1.42077003870004	[]	[]	9	hSpCas9	negative selection	2919004
41833305	41833328	22	-	27260157	SF268	viability	CAGCTCCGTGAGGGTCTCCATGG	SREBF2	ENSG00000198911	0.328512426270742	[]	[]	4	hSpCas9	negative selection	2919416
41833279	41833302	22	+	27260157	SF268	viability	CAGCGGCGAGCTGGGTGGTCTGG	SREBF2	ENSG00000198911	-0.516096890092859	[]	[]	-4	hSpCas9	negative selection	2920531
41833324	41833347	22	+	27260157	SF268	viability	GCTGGGCGACGAGCTGACCCTGG	SREBF2	ENSG00000198911	0.0982551962211445	[]	[]	0	hSpCas9	negative selection	2923540
41833274	41833297	22	+	27260157	SF268	viability	GACGACAGCGGCGAGCTGGGTGG	SREBF2	ENSG00000198911	1.18619249969051	[]	[]	9	hSpCas9	negative selection	2923792
41833262	41833285	22	+	27260157	SF268	viability	AGCCGGGCGATGGACGACAGCGG	SREBF2	ENSG00000198911	1.08543611552528	[]	[]	9	hSpCas9	negative selection	2927385
41866997	41867020	22	-	27260157	SF268	viability	TGAATGACCGTTGCACTGAAGGG	SREBF2	ENSG00000198911	0.488366675339724	[]	[]	7	hSpCas9	negative selection	2927973
41833270	41833293	22	+	27260157	SF268	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	1.63486033470158	[]	[]	9	hSpCas9	negative selection	2950323
41833342	41833365	22	-	27260157	SF268	viability	ACTCACCGTCGATGTCTCCCAGG	SREBF2	ENSG00000198911	-0.601185111924032	[]	[]	-5	hSpCas9	negative selection	2952052
41877327	41877350	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	-0.4390271621560681	[2,2]	[0,1]	-6	hSpCas9	positive selection	3023678
41870997	41871020	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	-0.3169894605545379	[3,3]	[2,2]	-4	hSpCas9	positive selection	3023679
41870923	41870946	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	-0.1929313229524415	[4,4]	[2,3]	-3	hSpCas9	positive selection	3023680
41870957	41870980	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.13706801538842386	[3,3]	[2,2]	3	hSpCas9	positive selection	3023681
41877327	41877350	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	0.28212239518759097	[2,2]	[1,2]	5	hSpCas9	positive selection	3091536
41870997	41871020	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	0.3096660727940715	[3,3]	[5,2]	5	hSpCas9	positive selection	3091537
41870923	41870946	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	0.22032005190183862	[4,4]	[3,3]	4	hSpCas9	positive selection	3091538
41870957	41870980	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.36406342025576005	[3,3]	[3,2]	6	hSpCas9	positive selection	3091539
41867003	41867026		+	24336571	A375	resistance to PLX after 7 days	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.1419174482398523	[19,16]	[18,21]	4	hSpCas9	positive selection	3147414
41875402	41875425		+	24336571	A375	resistance to PLX after 7 days	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	0.3363019716509925	[5,4]	[5,8]	8	hSpCas9	positive selection	3147415
41867209	41867232		+	24336571	A375	resistance to PLX after 7 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.17506411722324264	[10,9]	[9,13]	5	hSpCas9	positive selection	3147416
41867003	41867026		+	24336571	A375	resistance to PLX after 14 days	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.17421736579139935	[22,15]	[7,6]	-2	hSpCas9	positive selection	3205207
41875402	41875425		+	24336571	A375	resistance to PLX after 14 days	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	-0.144983127201867	[7,6]	[3,1]	-1	hSpCas9	positive selection	3205208
41867209	41867232		+	24336571	A375	resistance to PLX after 14 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.36587579562935146	[7,12]	[5,5]	3	hSpCas9	positive selection	3205209
41867003	41867026		+	24336571	A375	viability after 7 days	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.6270916372421363	[12]	[19,16]	8	hSpCas9	negative selection	3263000
41875402	41875425		+	24336571	A375	viability after 7 days	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	-0.0036165509241250504	[5]	[5,4]	0	hSpCas9	negative selection	3263001
41867209	41867232		+	24336571	A375	viability after 7 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.25269498671062557	[8]	[10,9]	4	hSpCas9	negative selection	3263002
41867003	41867026		+	24336571	A375	viability after 14 days	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.7080410969281934	[12]	[22,15]	8	hSpCas9	negative selection	3320793
41875402	41875425		+	24336571	A375	viability after 14 days	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	0.4401960717388491	[5]	[7,6]	5	hSpCas9	negative selection	3320794
41867209	41867232		+	24336571	A375	viability after 14 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.2164507120954185	[8]	[7,12]	3	hSpCas9	negative selection	3320795
41875556	41875579	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.8479352753081334	[84,84]	[0,0]	4	hSpCas9	positive selection	3394921
41875372	41875395	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	1.3148117061065954	[122,122]	[1,1]	5	hSpCas9	positive selection	3394922
41875328	41875351	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3394923
41877327	41877350	22	-	26780180	HT29	viability (Avana library 4 designs)	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	1.66092799647005	[]	[]	6	hSpCas9	negative selection	3462347
41870996	41871019	22	+	26780180	HT29	viability (Avana library 4 designs)	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	0.209426482678933	[]	[]	0	hSpCas9	negative selection	3462348
41870923	41870946	22	-	26780180	HT29	viability (Avana library 4 designs)	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	1.01996650406817	[]	[]	4	hSpCas9	negative selection	3462349
41870957	41870980	22	-	26780180	HT29	viability (Avana library 4 designs)	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	1.2036203626032	[]	[]	5	hSpCas9	negative selection	3462350
41870996	41871019	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	-6.78389431462187	[]	[]	-6	hSpCas9	negative selection	3563856
41870923	41870946	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	0.314878148516954	[]	[]	0	hSpCas9	negative selection	3563857
41870957	41870980	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	-0.458050455411501	[]	[]	0	hSpCas9	negative selection	3563858
41877327	41877350	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	2.63885388466317	[]	[]	4	hSpCas9	negative selection	3563859
41866868	41866891	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTTCTGAAAACAAGTCAGGG	SREBF2	ENSG00000198911	1.80179059650103	[]	[]	2	hSpCas9	negative selection	3563860
41870935	41870958	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCATCTGTCTTCAGTGTGG	SREBF2	ENSG00000198911	3.89124783026482	[]	[]	6	hSpCas9	negative selection	3563861
41870996	41871019	22	+	26780180	A375	viability (Avana lentiGuide)	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	-6.19592092629883	[]	[]	-9	hSpCas9	negative selection	3672515
41870923	41870946	22	-	26780180	A375	viability (Avana lentiGuide)	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	-3.00517874165903	[]	[]	-5	hSpCas9	negative selection	3672516
41870957	41870980	22	-	26780180	A375	viability (Avana lentiGuide)	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.350762403020915	[]	[]	0	hSpCas9	negative selection	3672517
41877327	41877350	22	-	26780180	A375	viability (Avana lentiGuide)	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	15.9276231048161	[]	[]	8	hSpCas9	negative selection	3672518
41866868	41866891	22	-	26780180	A375	viability (Avana lentiGuide)	GCTGTTCTGAAAACAAGTCAGGG	SREBF2	ENSG00000198911	-4.2351899954324	[]	[]	-7	hSpCas9	negative selection	3672519
41870935	41870958	22	-	26780180	A375	viability (Avana lentiGuide)	GCTGCCATCTGTCTTCAGTGTGG	SREBF2	ENSG00000198911	0.985013996658726	[]	[]	1	hSpCas9	negative selection	3672520
41870996	41871019	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	-0.526255299642931	[3]	[1,2]	-6	hSpCas9	positive selection	3781122
41870923	41870946	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	-0.03056564053171204	[6]	[6,5]	0	hSpCas9	positive selection	3781123
41870957	41870980	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	-0.20064700550185574	[4]	[3,3]	-3	hSpCas9	positive selection	3781124
41877327	41877350	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	0.02306163690187092	[5]	[5,4]	0	hSpCas9	positive selection	3781125
41866868	41866891	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTTCTGAAAACAAGTCAGGG	SREBF2	ENSG00000198911	-0.04851376992878579	[5]	[5,4]	-1	hSpCas9	positive selection	3781126
41870935	41870958	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCATCTGTCTTCAGTGTGG	SREBF2	ENSG00000198911	0.1635534943262654	[5]	[5,5]	4	hSpCas9	positive selection	3781127
41870996	41871019	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCACCACCCCTATCCAGACGG	SREBF2	ENSG00000198911	-0.13643805974231876	[4]	[1,4]	-2	hSpCas9	positive selection	3889729
41870923	41870946	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAGTGTGGTCAAAACAAGGG	SREBF2	ENSG00000198911	0.16988543068632453	[5]	[6,4]	4	hSpCas9	positive selection	3889730
41870957	41870980	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	-0.38466738461218897	[4]	[1,3]	-5	hSpCas9	positive selection	3889731
41877327	41877350	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCAGCAGGGAAGTCAGGGGG	SREBF2	ENSG00000198911	-0.3758009162700353	[4]	[3,2]	-5	hSpCas9	positive selection	3889732
41866868	41866891	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTTCTGAAAACAAGTCAGGG	SREBF2	ENSG00000198911	0.17499737145931646	[5]	[5,4]	4	hSpCas9	positive selection	3889733
41870935	41870958	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCATCTGTCTTCAGTGTGG	SREBF2	ENSG00000198911	0.06463233503507873	[6]	[4,5]	1	hSpCas9	positive selection	3889734
41867003	41867026	22	+	26780180	A375	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	1.04693139945904	[]	[]	5	hSpCas9	negative selection	3999422
41875556	41875579	22	+	26780180	A375	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	1.31491722814011	[]	[]	7	hSpCas9	negative selection	3999423
41875328	41875351	22	+	26780180	A375	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.981172183633525	[]	[]	4	hSpCas9	negative selection	3999424
41875592	41875615	22	-	26780180	A375	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	1.2828216678017	[]	[]	7	hSpCas9	negative selection	3999425
41867209	41867232	22	+	26780180	A375	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.0419715200205037	[]	[]	0	hSpCas9	negative selection	3999426
41875372	41875395	22	+	26780180	A375	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	1.39042151047176	[]	[]	7	hSpCas9	negative selection	3999427
41867003	41867026	22	+	26780180	HT29	viability (GeCKOv2 library)	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	1.39099978831426	[]	[]	7	hSpCas9	negative selection	4107388
41875556	41875579	22	+	26780180	HT29	viability (GeCKOv2 library)	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	1.39139468619024	[]	[]	7	hSpCas9	negative selection	4107389
41875328	41875351	22	+	26780180	HT29	viability (GeCKOv2 library)	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	1.60441436953636	[]	[]	8	hSpCas9	negative selection	4107390
41875592	41875615	22	-	26780180	HT29	viability (GeCKOv2 library)	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	1.01075850087432	[]	[]	4	hSpCas9	negative selection	4107391
41867209	41867232	22	+	26780180	HT29	viability (GeCKOv2 library)	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.372564588864562	[]	[]	1	hSpCas9	negative selection	4107392
41875372	41875395	22	+	26780180	HT29	viability (GeCKOv2 library)	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	1.92022025902838	[]	[]	9	hSpCas9	negative selection	4107393
41867003	41867026	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.15926049317095367	[3]	[1,2]	-4	hSpCas9	positive selection	4173608
41875402	41875425	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	-0.1530858659679869	[2]	[0,1]	-4	hSpCas9	positive selection	4173609
41867209	41867232	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.09166742393457242	[3]	[1,2]	-2	hSpCas9	positive selection	4173610
41867003	41867026	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.1634521829694696	[3]	[2,1,2,0]	1	hSpCas9	positive selection	4237630
41875402	41875425	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAAACTGCGCCAGGAGAACATGG	SREBF2	ENSG00000198911	-0.7199027096001824	[3]	[0,0,1,0]	-8	hSpCas9	positive selection	4237631
41867209	41867232	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.7214554596722671	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4237632
41867209	41867232	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.07028649397938636	[0]	[0,0]	-1	hSpCas9	positive selection	4300576
41867003	41867026	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.010176848236916225	[1]	[1,0]	0	hSpCas9	positive selection	4300577
41875592	41875615	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	-0.002797685130330796	[2]	[2,0]	0	hSpCas9	positive selection	4300578
41875556	41875579	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.2884226590558122	[2]	[2,0]	-5	hSpCas9	positive selection	4364831
41875372	41875395	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.23213946717823514	[2]	[2,2]	4	hSpCas9	positive selection	4364832
41875328	41875351	22	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.27697696079932077	[3]	[2,1]	-5	hSpCas9	positive selection	4364833
41867004	41867026	22	+	27760321	OCIAML3	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.6068933535536984	[448,345]	[347,628]	7	hSpCas9	negative selection	4443127
41867215	41867237	22	-	27760321	OCIAML3	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.592234550530028	[710,676]	[738,923]	7	hSpCas9	negative selection	4443128
41868696	41868718	22	-	27760321	OCIAML3	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.10982093617886779	[1083,916]	[790,906]	1	hSpCas9	negative selection	4443129
41870957	41870979	22	-	27760321	OCIAML3	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.3924857280703272	[370,263]	[259,403]	5	hSpCas9	negative selection	4443130
41877401	41877423	22	+	27760321	OCIAML3	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	0.6855339897073718	[894,879]	[978,1301]	7	hSpCas9	negative selection	4443131
41867004	41867026	22	+	27760321	OCIAML2	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.6115543313293923	[448,345]	[488,485]	8	hSpCas9	negative selection	4526590
41867215	41867237	22	-	27760321	OCIAML2	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.11019777905759387	[710,676]	[475,778]	1	hSpCas9	negative selection	4526591
41868696	41868718	22	-	27760321	OCIAML2	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.3849133085570451	[1083,916]	[977,1151]	5	hSpCas9	negative selection	4526592
41870957	41870979	22	-	27760321	OCIAML2	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.7479312692421889	[370,263]	[352,523]	8	hSpCas9	negative selection	4526593
41877401	41877423	22	+	27760321	OCIAML2	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	0.000846045541340823	[894,879]	[664,792]	0	hSpCas9	negative selection	4526594
41867004	41867026	22	+	27760321	MV411	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.08942300515871787	[448,345]	[163,365]	0	hSpCas9	negative selection	4610053
41867215	41867237	22	-	27760321	MV411	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.6332210350857362	[710,676]	[745,658]	5	hSpCas9	negative selection	4610054
41868696	41868718	22	-	27760321	MV411	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	1.20552275726406	[1083,916]	[1997,794]	8	hSpCas9	negative selection	4610055
41870957	41870979	22	-	27760321	MV411	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	1.2380840953009393	[370,263]	[259,832]	8	hSpCas9	negative selection	4610056
41877401	41877423	22	+	27760321	MV411	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.5554345892517767	[894,879]	[335,494]	-4	hSpCas9	negative selection	4610057
41867004	41867026	22	+	27760321	HL60	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.7033062950898897	[448,345]	[179,216]	-6	hSpCas9	negative selection	4693516
41867215	41867237	22	-	27760321	HL60	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	-1.3324647567977952	[710,676]	[188,263]	-8	hSpCas9	negative selection	4693517
41868696	41868718	22	-	27760321	HL60	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.13697726832024748	[1083,916]	[927,860]	1	hSpCas9	negative selection	4693518
41870957	41870979	22	-	27760321	HL60	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	-1.4463508369300317	[370,263]	[49,140]	-8	hSpCas9	negative selection	4693519
41877401	41877423	22	+	27760321	HL60	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-2.0734832363966254	[894,879]	[178,165]	-9	hSpCas9	negative selection	4693520
41867004	41867026	22	+	27760321	HT1080	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.12100535991728227	[345,269]	[131,134]	0	hSpCas9	negative selection	4776979
41867215	41867237	22	-	27760321	HT1080	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	-1.6476778184156111	[676,527]	[25,131]	-5	hSpCas9	negative selection	4776980
41868696	41868718	22	-	27760321	HT1080	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	-0.21114076592604758	[916,715]	[322,234]	-1	hSpCas9	negative selection	4776981
41870957	41870979	22	-	27760321	HT1080	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.24709229867417443	[263,205]	[165,50]	1	hSpCas9	negative selection	4776982
41877401	41877423	22	+	27760321	HT1080	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-1.578710406167003	[879,686]	[135,69]	-5	hSpCas9	negative selection	4776983
41867004	41867026	22	+	27760321	HT29	viability after 7 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.7156248610187068	[345,269]	[783,819,373]	9	hSpCas9	negative selection	4860442
41867215	41867237	22	-	27760321	HT29	viability after 7 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.31103965625543795	[676,527]	[882,853,1127]	5	hSpCas9	negative selection	4860443
41868696	41868718	22	-	27760321	HT29	viability after 7 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.1632963711122115	[916,715]	[1725,1062,825]	2	hSpCas9	negative selection	4860444
41870957	41870979	22	-	27760321	HT29	viability after 7 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.25140118493234376	[263,205]	[309,421,339]	4	hSpCas9	negative selection	4860445
41877401	41877423	22	+	27760321	HT29	viability after 7 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.4112513121459007	[879,686]	[785,842,649]	-6	hSpCas9	negative selection	4860446
41867004	41867026	22	+	27760321	HT29	viability after 25 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.9220157122675225	[345,269]	[646,876,454]	9	hSpCas9	negative selection	4943905
41867215	41867237	22	-	27760321	HT29	viability after 25 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.4122718765304004	[676,527]	[745,1010,1010]	4	hSpCas9	negative selection	4943906
41868696	41868718	22	-	27760321	HT29	viability after 25 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.11394867938615061	[916,715]	[1310,713,980]	1	hSpCas9	negative selection	4943907
41870957	41870979	22	-	27760321	HT29	viability after 25 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	1.3197030852523683	[263,205]	[785,492,729]	9	hSpCas9	negative selection	4943908
41877401	41877423	22	+	27760321	HT29	viability after 25 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.5711146803863375	[879,686]	[647,659,483]	-5	hSpCas9	negative selection	4943909
41867004	41867026	22	+	27760321	HT29	viability after 22 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.8400418587250125	[345,269]	[539,920,451]	8	hSpCas9	negative selection	5027368
41867215	41867237	22	-	27760321	HT29	viability after 22 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.16909817538750238	[676,527]	[735,783,830]	1	hSpCas9	negative selection	5027369
41868696	41868718	22	-	27760321	HT29	viability after 22 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.1615252869420709	[916,715]	[846,1259,1065]	1	hSpCas9	negative selection	5027370
41870957	41870979	22	-	27760321	HT29	viability after 22 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.7100190511612081	[263,205]	[564,312,451]	7	hSpCas9	negative selection	5027371
41877401	41877423	22	+	27760321	HT29	viability after 22 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.4102529436868575	[879,686]	[804,597,637]	-4	hSpCas9	negative selection	5027372
41867004	41867026	22	+	27760321	HT29	viability after 19 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	1.4929690746221074	[345,269]	[943,1012,1010]	9	hSpCas9	negative selection	5110831
41867215	41867237	22	-	27760321	HT29	viability after 19 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.5087987245532756	[676,527]	[1264,983,730]	5	hSpCas9	negative selection	5110832
41868696	41868718	22	-	27760321	HT29	viability after 19 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.23411076207131276	[916,715]	[1098,1112,1082]	2	hSpCas9	negative selection	5110833
41870957	41870979	22	-	27760321	HT29	viability after 19 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	1.0706290879959155	[263,205]	[1105,272,377]	9	hSpCas9	negative selection	5110834
41877401	41877423	22	+	27760321	HT29	viability after 19 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.3881547803013248	[879,686]	[1097,530,475]	-4	hSpCas9	negative selection	5110835
41867004	41867026	22	+	27760321	HT29	viability after 16 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.8135594229864218	[345,269]	[773,593,464]	8	hSpCas9	negative selection	5194294
41867215	41867237	22	-	27760321	HT29	viability after 16 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.3619994863980688	[676,527]	[880,832,886]	4	hSpCas9	negative selection	5194295
41868696	41868718	22	-	27760321	HT29	viability after 16 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	-0.0249239652873412	[916,715]	[1063,981,660]	0	hSpCas9	negative selection	5194296
41870957	41870979	22	-	27760321	HT29	viability after 16 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.7278011690824068	[263,205]	[693,343,294]	8	hSpCas9	negative selection	5194297
41877401	41877423	22	+	27760321	HT29	viability after 16 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.2757360388510931	[879,686]	[602,866,686]	-3	hSpCas9	negative selection	5194298
41867004	41867026	22	+	27760321	HT29	viability after 13 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.6246928016011346	[345,269]	[717,616,330]	7	hSpCas9	negative selection	5277757
41867215	41867237	22	-	27760321	HT29	viability after 13 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.00740496978910965	[676,527]	[835,480,784]	0	hSpCas9	negative selection	5277758
41868696	41868718	22	-	27760321	HT29	viability after 13 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.15464992183707005	[916,715]	[1367,869,931]	2	hSpCas9	negative selection	5277759
41870957	41870979	22	-	27760321	HT29	viability after 13 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	0.7509566888549214	[263,205]	[559,287,523]	8	hSpCas9	negative selection	5277760
41877401	41877423	22	+	27760321	HT29	viability after 13 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.6178324343496838	[879,686]	[436,675,659]	-6	hSpCas9	negative selection	5277761
41867004	41867026	22	+	27760321	HT29	viability after 10 days	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.8419348646787532	[345,269]	[481,826,760]	9	hSpCas9	negative selection	5361220
41867215	41867237	22	-	27760321	HT29	viability after 10 days	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.2862747551741983	[676,527]	[874,1019,860]	4	hSpCas9	negative selection	5361221
41868696	41868718	22	-	27760321	HT29	viability after 10 days	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	-0.2699267632992315	[916,715]	[922,842,771]	-3	hSpCas9	negative selection	5361222
41870957	41870979	22	-	27760321	HT29	viability after 10 days	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	1.0325047836481192	[263,205]	[490,679,630]	9	hSpCas9	negative selection	5361223
41877401	41877423	22	+	27760321	HT29	viability after 10 days	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	-0.2685771476189944	[879,686]	[641,684,1098]	-3	hSpCas9	negative selection	5361224
41867004	41867026	22	+	27760321	MOLM13	viability	GTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	1.5599641974069407	[448,345]	[509,780]	9	hSpCas9	negative selection	5444683
41867215	41867237	22	-	27760321	MOLM13	viability	ATGATCCTCGTCTGCGGAGTGG	SREBF2	ENSG00000198911	0.14573090027298763	[710,676]	[497,378]	1	hSpCas9	negative selection	5444684
41868696	41868718	22	-	27760321	MOLM13	viability	CGTTTGTGTCAGCACCCGCTGG	SREBF2	ENSG00000198911	0.12676286475846	[1083,916]	[1015,271]	0	hSpCas9	negative selection	5444685
41870957	41870979	22	-	27760321	MOLM13	viability	CTGGACCGCAGCCATAACAGGG	SREBF2	ENSG00000198911	2.102112630640434	[370,263]	[868,668]	9	hSpCas9	negative selection	5444686
41877401	41877423	22	+	27760321	MOLM13	viability	GTGTCCTGTCATTCGAGTCAGG	SREBF2	ENSG00000198911	0.09158374395175994	[894,879]	[730,367]	0	hSpCas9	negative selection	5444687
41833143	41833166	22	+	27661255	K562	viability	GCGGGTGGCACCCGTCGGTGAGG	SREBF2	ENSG00000198911	0.1946097926269631	[966,878]	[909,789]	6	dCas9-KRAB	negative selection	5514258
41833146	41833169	22	+	27661255	K562	viability	GGTGGCACCCGTCGGTGAGGCGG	SREBF2	ENSG00000198911	0.023524753890721173	[517,454]	[396,394]	0	dCas9-KRAB	negative selection	5514259
41833545	41833568	22	-	27661255	K562	viability	GATCCCACGGCCTCCCGGAGCGG	SREBF2	ENSG00000198911	0.06485194493680135	[1294,1469]	[1233,1082]	2	dCas9-KRAB	negative selection	5514260
41867209	41867232	22	+	27260156	BXPC3	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.18430635433527431	[18]	[1,49,9,5]	-4	hSpCas9	negative selection	5573036
41867003	41867026	22	+	27260156	BXPC3	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.22958175788504587	[109]	[74,74,135,111]	-5	hSpCas9	negative selection	5573037
41875592	41875615	22	-	27260156	BXPC3	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.3352527181588856	[239]	[266,298,346,363]	7	hSpCas9	negative selection	5573038
41875556	41875579	22	+	27260156	BXPC3	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.003315582719117971	[375]	[295,405,357,540]	0	hSpCas9	negative selection	5637291
41875372	41875395	22	+	27260156	BXPC3	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.2862399519307596	[407]	[350,339,309,401]	-6	hSpCas9	negative selection	5637292
41875328	41875351	22	+	27260156	BXPC3	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.2301989963311541	[633]	[542,504,543,684]	-5	hSpCas9	negative selection	5637293
41867209	41867232	22	+	27260156	A673	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.8852790198316596	[18]	[2,12,22,8]	-9	hSpCas9	negative selection	5694287
41867003	41867026	22	+	27260156	A673	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.02824403114890517	[109]	[124,124,98,170]	0	hSpCas9	negative selection	5694288
41875592	41875615	22	-	27260156	A673	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.5241519444279317	[239]	[488,343,335,503]	9	hSpCas9	negative selection	5694289
41875556	41875579	22	+	27260156	A673	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.2715689796295736	[375]	[476,280,385,364]	-6	hSpCas9	negative selection	5758542
41875372	41875395	22	+	27260156	A673	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.011064457724620919	[407]	[509,466,467,502]	0	hSpCas9	negative selection	5758543
41875328	41875351	22	+	27260156	A673	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.16052260764999648	[633]	[663,604,687,770]	-4	hSpCas9	negative selection	5758544
41867209	41867232	22	+	27260156	A375	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.507906368220266	[18]	[0,0,58,0]	-6	hSpCas9	negative selection	5815538
41867003	41867026	22	+	27260156	A375	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.35617581855468794	[109]	[168,83,255,139]	5	hSpCas9	negative selection	5815539
41875592	41875615	22	-	27260156	A375	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.5324540246545262	[239]	[421,540,379,307]	7	hSpCas9	negative selection	5815540
41875556	41875579	22	+	27260156	A375	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.06897838355593977	[375]	[237,578,282,574]	-1	hSpCas9	negative selection	5879793
41875372	41875395	22	+	27260156	A375	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.28923563011315684	[407]	[593,937,450,413]	4	hSpCas9	negative selection	5879794
41875328	41875351	22	+	27260156	A375	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.038897648948034436	[633]	[791,952,690,644]	0	hSpCas9	negative selection	5879795
41867209	41867232	22	+	27260156	COLO741	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.0590349246204829	[18]	[23,0,10]	-9	hSpCas9	negative selection	5936789
41867003	41867026	22	+	27260156	COLO741	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.6322217206181318	[109]	[92,87,90]	-8	hSpCas9	negative selection	5936790
41875592	41875615	22	-	27260156	COLO741	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.08727097686358254	[239]	[380,327,275]	1	hSpCas9	negative selection	5936791
41875556	41875579	22	+	27260156	COLO741	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.4208160218866166	[375]	[366,315,390]	-7	hSpCas9	negative selection	6001044
41875372	41875395	22	+	27260156	COLO741	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.34895495025737233	[407]	[498,403,336]	-6	hSpCas9	negative selection	6001045
41875328	41875351	22	+	27260156	COLO741	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.61451498517195	[633]	[612,547,438]	-8	hSpCas9	negative selection	6001046
41867209	41867232	22	+	27260156	CAL120	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.0861691100220376	[18]	[20,8,4]	-8	hSpCas9	negative selection	6058040
41867003	41867026	22	+	27260156	CAL120	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.7224057185984352	[109]	[85,62,99]	-7	hSpCas9	negative selection	6058041
41875592	41875615	22	-	27260156	CAL120	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	-0.18721800925366616	[239]	[329,204,261]	-3	hSpCas9	negative selection	6058042
41875556	41875579	22	+	27260156	CAL120	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.7754718029851478	[375]	[249,270,294]	-8	hSpCas9	negative selection	6122295
41875372	41875395	22	+	27260156	CAL120	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.3639215768221818	[407]	[1062,276,680]	5	hSpCas9	negative selection	6122296
41875328	41875351	22	+	27260156	CAL120	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.1380915999693888	[633]	[853,705,612]	-2	hSpCas9	negative selection	6122297
41867209	41867232	22	+	27260156	CADOES1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.3775905731088729	[18]	[5,2,41,2]	-6	hSpCas9	negative selection	6179291
41867003	41867026	22	+	27260156	CADOES1	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.21480936047127264	[109]	[134,76,89,48]	-4	hSpCas9	negative selection	6179292
41875592	41875615	22	-	27260156	CADOES1	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.5762472282153324	[239]	[344,315,493,169]	8	hSpCas9	negative selection	6179293
41875556	41875579	22	+	27260156	CADOES1	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.29482105658137636	[375]	[241,247,346,303]	-5	hSpCas9	negative selection	6243546
41875372	41875395	22	+	27260156	CADOES1	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.023824429779015666	[407]	[486,378,287,388]	0	hSpCas9	negative selection	6243547
41875328	41875351	22	+	27260156	CADOES1	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.047089339862637525	[633]	[565,487,624,604]	-1	hSpCas9	negative selection	6243548
41867209	41867232	22	+	27260156	EWS502	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.20782838036259133	[18]	[23,10,17,15]	-4	hSpCas9	negative selection	6300542
41867003	41867026	22	+	27260156	EWS502	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.2539886911147742	[109]	[123,188,61,181]	4	hSpCas9	negative selection	6300543
41875592	41875615	22	-	27260156	EWS502	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.5189590645396471	[239]	[285,265,406,521]	8	hSpCas9	negative selection	6300544
41875556	41875579	22	+	27260156	EWS502	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.15468919078603544	[375]	[277,452,318,386]	-3	hSpCas9	negative selection	6364797
41875372	41875395	22	+	27260156	EWS502	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.04258903439369105	[407]	[363,554,461,399]	0	hSpCas9	negative selection	6364798
41875328	41875351	22	+	27260156	EWS502	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.029837597119195036	[633]	[614,564,568,904]	0	hSpCas9	negative selection	6364799
41867209	41867232	22	+	27260156	EW8	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.20556442626235594	[18]	[34,11,4,22]	4	hSpCas9	negative selection	6421793
41867003	41867026	22	+	27260156	EW8	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.6653193644343633	[109]	[187,107,93,187]	9	hSpCas9	negative selection	6421794
41875592	41875615	22	-	27260156	EW8	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.3119341392559821	[239]	[241,191,305,213]	6	hSpCas9	negative selection	6421795
41875556	41875579	22	+	27260156	EW8	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.06960339299046003	[375]	[318,216,321,299]	-1	hSpCas9	negative selection	6486048
41875372	41875395	22	+	27260156	EW8	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.2053744165969567	[407]	[422,392,348,368]	4	hSpCas9	negative selection	6486049
41875328	41875351	22	+	27260156	EW8	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.2901562667909465	[633]	[440,320,366,560]	-5	hSpCas9	negative selection	6486050
41867209	41867232	22	+	27260156	CORL105	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.793132995656813	[18]	[21,4,13,10]	-8	hSpCas9	negative selection	6543044
41867003	41867026	22	+	27260156	CORL105	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.6047438174119644	[109]	[80,58,134,71]	-8	hSpCas9	negative selection	6543045
41875592	41875615	22	-	27260156	CORL105	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.2876153965387477	[239]	[441,255,293,376]	5	hSpCas9	negative selection	6543046
41875556	41875579	22	+	27260156	CORL105	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.002658282186743688	[375]	[484,529,428,311]	0	hSpCas9	negative selection	6607299
41875372	41875395	22	+	27260156	CORL105	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.031229845462325767	[407]	[562,389,483,439]	0	hSpCas9	negative selection	6607300
41875328	41875351	22	+	27260156	CORL105	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.14467895730649466	[633]	[699,869,905,813]	2	hSpCas9	negative selection	6607301
41867209	41867232	22	+	27260156	HS294T	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.4953220823416826	[18]	[8,2,0,7]	-6	hSpCas9	negative selection	6664295
41867003	41867026	22	+	27260156	HS294T	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.42550128309200574	[109]	[38,38,103,46]	6	hSpCas9	negative selection	6664296
41875592	41875615	22	-	27260156	HS294T	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.20881484965060937	[239]	[131,121,52,120]	3	hSpCas9	negative selection	6664297
41875556	41875579	22	+	27260156	HS294T	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.4680036039045103	[375]	[153,82,90,540]	6	hSpCas9	negative selection	6728550
41875372	41875395	22	+	27260156	HS294T	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.9648475809711796	[407]	[380,215,284,351]	9	hSpCas9	negative selection	6728551
41875328	41875351	22	+	27260156	HS294T	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.20382532369653	[633]	[230,359,295,235]	2	hSpCas9	negative selection	6728552
41867209	41867232	22	+	27260156	HCC44	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.35096902500645744	[18]	[0,4,58,9]	-5	hSpCas9	negative selection	6785546
41867003	41867026	22	+	27260156	HCC44	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.33989228395565085	[109]	[102,87,87,112]	-5	hSpCas9	negative selection	6785547
41875592	41875615	22	-	27260156	HCC44	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.0723222919803097	[239]	[379,224,319,238]	1	hSpCas9	negative selection	6785548
41875556	41875579	22	+	27260156	HCC44	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.4991546635804972	[375]	[325,269,328,287]	-6	hSpCas9	negative selection	6849801
41875372	41875395	22	+	27260156	HCC44	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.2666174518004824	[407]	[610,438,875,372]	4	hSpCas9	negative selection	6849802
41875328	41875351	22	+	27260156	HCC44	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.022099959857821594	[633]	[783,676,999,511]	0	hSpCas9	negative selection	6849803
41867209	41867232	22	+	27260156	G402	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-2.3197098642018172	[18]	[0,0,14,0]	-9	hSpCas9	negative selection	6906797
41867003	41867026	22	+	27260156	G402	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.5963299248365912	[109]	[118,248,50,373]	7	hSpCas9	negative selection	6906798
41875592	41875615	22	-	27260156	G402	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.747191191532319	[239]	[576,350,538,500]	8	hSpCas9	negative selection	6906799
41875556	41875579	22	+	27260156	G402	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.6107675677585805	[375]	[181,642,132,247]	-6	hSpCas9	negative selection	6971052
41875372	41875395	22	+	27260156	G402	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.05967557786987501	[407]	[623,331,522,594]	0	hSpCas9	negative selection	6971053
41875328	41875351	22	+	27260156	G402	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.1082608843172691	[633]	[564,1185,698,436]	-1	hSpCas9	negative selection	6971054
41867209	41867232	22	+	27260156	L33	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.18646460739013015	[18]	[23,2,9,38]	4	hSpCas9	negative selection	7028048
41867003	41867026	22	+	27260156	L33	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.19483980620117514	[109]	[122,58,80,107]	4	hSpCas9	negative selection	7028049
41875592	41875615	22	-	27260156	L33	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.08453667490786299	[239]	[314,109,175,153]	2	hSpCas9	negative selection	7028050
41875556	41875579	22	+	27260156	L33	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.3587410295543694	[375]	[262,140,211,229]	-7	hSpCas9	negative selection	7092303
41875372	41875395	22	+	27260156	L33	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.6804686182688329	[407]	[197,137,116,297]	-9	hSpCas9	negative selection	7092304
41875328	41875351	22	+	27260156	L33	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.11650237972719957	[633]	[604,238,383,539]	-3	hSpCas9	negative selection	7092305
41867209	41867232	22	+	27260156	K562	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.4272367986975185	[18]	[7,0,0,13]	-9	hSpCas9	negative selection	7149299
41867003	41867026	22	+	27260156	K562	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.28129005873505	[109]	[74,49,85,104]	-3	hSpCas9	negative selection	7149300
41875592	41875615	22	-	27260156	K562	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.9417560629031778	[239]	[224,300,867,239]	9	hSpCas9	negative selection	7149301
41875556	41875579	22	+	27260156	K562	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.7636350219922033	[375]	[172,260,82,261]	-7	hSpCas9	negative selection	7213554
41875372	41875395	22	+	27260156	K562	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.5627248632297681	[407]	[293,429,553,801]	7	hSpCas9	negative selection	7213555
41875328	41875351	22	+	27260156	K562	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.021430021080395878	[633]	[349,665,679,512]	0	hSpCas9	negative selection	7213556
41867209	41867232	22	+	27260156	HT29	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.6719850310183784	[18]	[2,7,26,17]	-8	hSpCas9	negative selection	7270550
41867003	41867026	22	+	27260156	HT29	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.004772762200658143	[109]	[190,125,148,76]	0	hSpCas9	negative selection	7270551
41875592	41875615	22	-	27260156	HT29	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.6177653854211149	[239]	[477,426,479,407]	9	hSpCas9	negative selection	7270552
41875556	41875579	22	+	27260156	HT29	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.046152687766363665	[375]	[449,388,423,493]	-1	hSpCas9	negative selection	7334805
41875372	41875395	22	+	27260156	HT29	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.04585371077917813	[407]	[460,705,548,359]	0	hSpCas9	negative selection	7334806
41875328	41875351	22	+	27260156	HT29	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.05666119190377028	[633]	[735,655,1061,736]	1	hSpCas9	negative selection	7334807
41867209	41867232	22	+	27260156	MHHES1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.5929054767192223	[18]	[7,0,28,15]	-8	hSpCas9	negative selection	7391801
41867003	41867026	22	+	27260156	MHHES1	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.10594557935681626	[109]	[162,111,170,94]	2	hSpCas9	negative selection	7391802
41875592	41875615	22	-	27260156	MHHES1	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.43646734704874857	[239]	[388,457,247,369]	7	hSpCas9	negative selection	7391803
41875556	41875579	22	+	27260156	MHHES1	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.40445238131415007	[375]	[310,478,219,284]	-6	hSpCas9	negative selection	7456056
41875372	41875395	22	+	27260156	MHHES1	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.10313670591602256	[407]	[445,647,367,294]	-2	hSpCas9	negative selection	7456057
41875328	41875351	22	+	27260156	MHHES1	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.06084902235650452	[633]	[865,656,616,616]	-1	hSpCas9	negative selection	7456058
41867209	41867232	22	+	27260156	MEWO	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.33905423645681054	[18]	[19,15,30]	7	hSpCas9	negative selection	7513052
41867003	41867026	22	+	27260156	MEWO	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.07501662340829851	[109]	[168,73,63]	-2	hSpCas9	negative selection	7513053
41875592	41875615	22	-	27260156	MEWO	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.6073628685053729	[239]	[398,376,260]	9	hSpCas9	negative selection	7513054
41875556	41875579	22	+	27260156	MEWO	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.2244709550428076	[375]	[457,408,374]	5	hSpCas9	negative selection	7577307
41875372	41875395	22	+	27260156	MEWO	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.24985014756164106	[407]	[330,299,333]	-5	hSpCas9	negative selection	7577308
41875328	41875351	22	+	27260156	MEWO	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.03296014022277027	[633]	[659,510,583]	0	hSpCas9	negative selection	7577309
41867209	41867232	22	+	27260156	LNCAPCLONEFGC	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.4895611121441501	[18]	[28,0,15,3]	-6	hSpCas9	negative selection	7634303
41867003	41867026	22	+	27260156	LNCAPCLONEFGC	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.1433220380168021	[109]	[47,85,83,142]	-2	hSpCas9	negative selection	7634304
41875592	41875615	22	-	27260156	LNCAPCLONEFGC	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.38197312637367387	[239]	[298,236,277,320]	6	hSpCas9	negative selection	7634305
41875556	41875579	22	+	27260156	LNCAPCLONEFGC	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.45317962119616806	[375]	[251,279,296,170]	-6	hSpCas9	negative selection	7698558
41875372	41875395	22	+	27260156	LNCAPCLONEFGC	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.15190398743545766	[407]	[344,333,426,544]	2	hSpCas9	negative selection	7698559
41875328	41875351	22	+	27260156	LNCAPCLONEFGC	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.2062314397753291	[633]	[518,417,532,530]	-3	hSpCas9	negative selection	7698560
41867209	41867232	22	+	27260156	PANC0327	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-3.7581218326076815	[18]	[0,0,0,1]	-9	hSpCas9	negative selection	7755554
41867003	41867026	22	+	27260156	PANC0327	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-1.4437277007051836	[109]	[43,53,26,16]	-9	hSpCas9	negative selection	7755555
41875592	41875615	22	-	27260156	PANC0327	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.7235063649596212	[239]	[384,416,193,405]	9	hSpCas9	negative selection	7755556
41875556	41875579	22	+	27260156	PANC0327	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.4188460505851179	[375]	[289,361,157,177]	-6	hSpCas9	negative selection	7819809
41875372	41875395	22	+	27260156	PANC0327	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.49815296779340246	[407]	[466,112,191,289]	-6	hSpCas9	negative selection	7819810
41875328	41875351	22	+	27260156	PANC0327	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.7402903619544734	[633]	[365,327,339,317]	-7	hSpCas9	negative selection	7819811
41867209	41867232	22	+	27260156	NCIH2009	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.45224764434692943	[18]	[0,48,3]	-5	hSpCas9	negative selection	7876805
41867003	41867026	22	+	27260156	NCIH2009	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.24190361580210507	[109]	[213,142,194]	3	hSpCas9	negative selection	7876806
41875592	41875615	22	-	27260156	NCIH2009	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.3175819127044027	[239]	[566,330,385]	4	hSpCas9	negative selection	7876807
41875556	41875579	22	+	27260156	NCIH2009	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.18962998705466638	[375]	[589,221,598]	-3	hSpCas9	negative selection	7941060
41875372	41875395	22	+	27260156	NCIH2009	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.6702178717180192	[407]	[440,380,267]	-7	hSpCas9	negative selection	7941061
41875328	41875351	22	+	27260156	NCIH2009	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.05111957011815721	[633]	[995,925,844]	0	hSpCas9	negative selection	7941062
41867209	41867232	22	+	27260156	NCIH1373	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.4678012322429241	[18]	[0,18,0,1]	-9	hSpCas9	negative selection	7998056
41867003	41867026	22	+	27260156	NCIH1373	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.21421629712511847	[109]	[244,120,146,18]	2	hSpCas9	negative selection	7998057
41875592	41875615	22	-	27260156	NCIH1373	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.9077040094434455	[239]	[730,490,401,111]	8	hSpCas9	negative selection	7998058
41875556	41875579	22	+	27260156	NCIH1373	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.05557498668304639	[375]	[361,379,440,113]	0	hSpCas9	negative selection	8062311
41875372	41875395	22	+	27260156	NCIH1373	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.33846699041032613	[407]	[594,254,296,90]	-3	hSpCas9	negative selection	8062312
41875328	41875351	22	+	27260156	NCIH1373	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.027933362139530127	[633]	[862,609,689,201]	0	hSpCas9	negative selection	8062313
41867209	41867232	22	+	27260156	PATU8902	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.20805860261176434	[18]	[6,57,20,3]	-2	hSpCas9	negative selection	8119307
41867003	41867026	22	+	27260156	PATU8902	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.889163356633186	[109]	[108,421,293,310]	8	hSpCas9	negative selection	8119308
41875592	41875615	22	-	27260156	PATU8902	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.9076908592989928	[239]	[459,526,1055,312]	8	hSpCas9	negative selection	8119309
41875556	41875579	22	+	27260156	PATU8902	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.3193956475661577	[375]	[364,468,1018,664]	3	hSpCas9	negative selection	8183562
41875372	41875395	22	+	27260156	PATU8902	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.2504020669769391	[407]	[368,590,497,440]	-3	hSpCas9	negative selection	8183563
41875328	41875351	22	+	27260156	PATU8902	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.3228279975754997	[633]	[1039,1025,692,1845]	3	hSpCas9	negative selection	8183564
41867209	41867232	22	+	27260156	PANC1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.877135030274646	[18]	[7,1,1,4]	-9	hSpCas9	negative selection	8240558
41867003	41867026	22	+	27260156	PANC1	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.3071180893810792	[109]	[92,48,62,227]	5	hSpCas9	negative selection	8240559
41875592	41875615	22	-	27260156	PANC1	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.4125028000287858	[239]	[204,541,224,190]	6	hSpCas9	negative selection	8240560
41875556	41875579	22	+	27260156	PANC1	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.3501666404991163	[375]	[193,283,245,286]	-5	hSpCas9	negative selection	8304813
41875372	41875395	22	+	27260156	PANC1	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.0785947491162707	[407]	[306,380,402,254]	-1	hSpCas9	negative selection	8304814
41875328	41875351	22	+	27260156	PANC1	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.1751102982522329	[633]	[566,440,378,516]	-3	hSpCas9	negative selection	8304815
41867209	41867232	22	+	27260156	PANC0813	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.5668080000284164	[18]	[6,1,7,40]	-7	hSpCas9	negative selection	8361809
41867003	41867026	22	+	27260156	PANC0813	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.12439135827528824	[109]	[121,180,129,128]	2	hSpCas9	negative selection	8361810
41875592	41875615	22	-	27260156	PANC0813	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.5894174406637782	[239]	[505,345,467,385]	8	hSpCas9	negative selection	8361811
41875556	41875579	22	+	27260156	PANC0813	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.20026373523929752	[375]	[387,369,438,342]	-3	hSpCas9	negative selection	8426064
41875372	41875395	22	+	27260156	PANC0813	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.14307925246238612	[407]	[492,771,291,552]	2	hSpCas9	negative selection	8426065
41875328	41875351	22	+	27260156	PANC0813	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.02223054338245356	[633]	[573,890,697,752]	0	hSpCas9	negative selection	8426066
41867209	41867232	22	+	27260156	RDES	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-2.552072323007704	[18]	[3,6,0,1]	-9	hSpCas9	negative selection	8483060
41867003	41867026	22	+	27260156	RDES	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.09058321654492829	[109]	[108,68,176,126]	-1	hSpCas9	negative selection	8483061
41875592	41875615	22	-	27260156	RDES	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.6766539683913616	[239]	[504,375,379,483]	9	hSpCas9	negative selection	8483062
41875556	41875579	22	+	27260156	RDES	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.39187908420458595	[375]	[306,290,385,334]	-6	hSpCas9	negative selection	8547315
41875372	41875395	22	+	27260156	RDES	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.15325315640106268	[407]	[358,371,568,879]	2	hSpCas9	negative selection	8547316
41875328	41875351	22	+	27260156	RDES	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.16126568409952785	[633]	[482,573,702,915]	-3	hSpCas9	negative selection	8547317
41867209	41867232	22	+	27260156	PC3	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.4200805881262273	[18]	[36,6,11,30]	8	hSpCas9	negative selection	8604311
41867003	41867026	22	+	27260156	PC3	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.4470642662915649	[109]	[70,277,177,93]	8	hSpCas9	negative selection	8604312
41875592	41875615	22	-	27260156	PC3	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.028219513057571977	[239]	[153,240,405,253]	0	hSpCas9	negative selection	8604313
41875556	41875579	22	+	27260156	PC3	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.22817655606022058	[375]	[243,315,294,414]	-5	hSpCas9	negative selection	8668566
41875372	41875395	22	+	27260156	PC3	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.08498636643952553	[407]	[317,292,435,497]	-2	hSpCas9	negative selection	8668567
41875328	41875351	22	+	27260156	PC3	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.3795205264937451	[633]	[259,476,883,537]	-7	hSpCas9	negative selection	8668568
41867209	41867232	22	+	27260156	PATU8988T	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.6681650380992377	[18]	[0,11,1,8]	-9	hSpCas9	negative selection	8725562
41867003	41867026	22	+	27260156	PATU8988T	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.2736936744432654	[109]	[181,103,6,58]	-4	hSpCas9	negative selection	8725563
41875592	41875615	22	-	27260156	PATU8988T	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.30599582939039205	[239]	[302,299,291,249]	5	hSpCas9	negative selection	8725564
41875556	41875579	22	+	27260156	PATU8988T	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.4346538348165684	[375]	[265,205,322,273]	-6	hSpCas9	negative selection	8789817
41875372	41875395	22	+	27260156	PATU8988T	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.39189482421303556	[407]	[189,379,364,270]	-6	hSpCas9	negative selection	8789818
41875328	41875351	22	+	27260156	PATU8988T	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.002971650460988351	[633]	[394,531,890,626]	0	hSpCas9	negative selection	8789819
41867209	41867232	22	+	27260156	T47D	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-1.6201240432509207	[18]	[3,7,2,13]	-9	hSpCas9	negative selection	8846813
41867003	41867026	22	+	27260156	T47D	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.31077633975461705	[109]	[104,62,105,143]	-6	hSpCas9	negative selection	8846814
41875592	41875615	22	-	27260156	T47D	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.39054750055572185	[239]	[428,354,357,323]	8	hSpCas9	negative selection	8846815
41875556	41875579	22	+	27260156	T47D	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.2045591469135456	[375]	[401,340,350,431]	-4	hSpCas9	negative selection	8911068
41875372	41875395	22	+	27260156	T47D	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.04621837118496874	[407]	[468,426,438,638]	1	hSpCas9	negative selection	8911069
41875328	41875351	22	+	27260156	T47D	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.08164540354600791	[633]	[724,586,727,762]	-2	hSpCas9	negative selection	8911070
41867209	41867232	22	+	27260156	SU8686	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.843167170409826	[18]	[13,16,0,7]	-8	hSpCas9	negative selection	8968064
41867003	41867026	22	+	27260156	SU8686	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.08069203219033927	[109]	[106,102,129,124]	1	hSpCas9	negative selection	8968065
41875592	41875615	22	-	27260156	SU8686	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.28340936849534726	[239]	[215,223,314,443]	5	hSpCas9	negative selection	8968066
41875556	41875579	22	+	27260156	SU8686	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.023697026991302772	[375]	[233,305,370,616]	0	hSpCas9	negative selection	9032319
41875372	41875395	22	+	27260156	SU8686	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.42621247098415516	[407]	[301,244,230,453]	-6	hSpCas9	negative selection	9032320
41875328	41875351	22	+	27260156	SU8686	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.19531412852678048	[633]	[514,455,559,701]	-3	hSpCas9	negative selection	9032321
41867209	41867232	22	+	27260156	SKES1	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.14425583872366676	[18]	[15,0,9,36]	-3	hSpCas9	negative selection	9089315
41867003	41867026	22	+	27260156	SKES1	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	0.3188502078631239	[109]	[242,146,105,73]	6	hSpCas9	negative selection	9089316
41875592	41875615	22	-	27260156	SKES1	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.26617171528228967	[239]	[366,317,248,235]	5	hSpCas9	negative selection	9089317
41875556	41875579	22	+	27260156	SKES1	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.014386006161534293	[375]	[400,362,394,355]	0	hSpCas9	negative selection	9153570
41875372	41875395	22	+	27260156	SKES1	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.22596126563802396	[407]	[457,326,330,291]	-5	hSpCas9	negative selection	9153571
41875328	41875351	22	+	27260156	SKES1	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.13497055787338041	[633]	[603,605,603,499]	-3	hSpCas9	negative selection	9153572
41867209	41867232	22	+	27260156	TOV112D	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.09484160378648543	[18]	[13,3,48,0]	-2	hSpCas9	negative selection	9210566
41867003	41867026	22	+	27260156	TOV112D	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.1567964706933873	[109]	[60,122,154,59]	-3	hSpCas9	negative selection	9210567
41875592	41875615	22	-	27260156	TOV112D	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.36004853606238996	[239]	[393,360,347,154]	6	hSpCas9	negative selection	9210568
41875556	41875579	22	+	27260156	TOV112D	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	0.09806321712931718	[375]	[308,709,393,269]	2	hSpCas9	negative selection	9274821
41875372	41875395	22	+	27260156	TOV112D	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.051678625819349205	[407]	[527,367,429,258]	-1	hSpCas9	negative selection	9274822
41875328	41875351	22	+	27260156	TOV112D	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.22750643308859902	[633]	[778,1252,508,564]	4	hSpCas9	negative selection	9274823
41867209	41867232	22	+	27260156	TC71	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.3370096558841773	[18]	[9,22,21,8]	-7	hSpCas9	negative selection	9331817
41867003	41867026	22	+	27260156	TC71	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.0030308623301609217	[109]	[144,92,105,126]	0	hSpCas9	negative selection	9331818
41875592	41875615	22	-	27260156	TC71	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.21287961029636582	[239]	[260,334,263,336]	5	hSpCas9	negative selection	9331819
41875556	41875579	22	+	27260156	TC71	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.1550501350204011	[375]	[336,326,375,410]	-4	hSpCas9	negative selection	9396072
41875372	41875395	22	+	27260156	TC71	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	-0.32547946794339155	[407]	[292,425,368,305]	-7	hSpCas9	negative selection	9396073
41875328	41875351	22	+	27260156	TC71	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	-0.017480869468180893	[633]	[698,633,617,739]	0	hSpCas9	negative selection	9396074
41867209	41867232	22	+	27260156	TC32	viability	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.8540455496691619	[18]	[15,0,18,6]	-9	hSpCas9	negative selection	9453068
41867003	41867026	22	+	27260156	TC32	viability	AGTGCAACGGTCATTCACCCAGG	SREBF2	ENSG00000198911	-0.028082517203640744	[109]	[89,95,90,124]	0	hSpCas9	negative selection	9453069
41875592	41875615	22	-	27260156	TC32	viability	GATTAAAGTCCTCGATCTTCAGG	SREBF2	ENSG00000198911	0.7070014981762245	[239]	[354,199,525,469]	9	hSpCas9	negative selection	9453070
41875556	41875579	22	+	27260156	TC32	viability	CATCGACCTAGGCAGTCTGGTGG	SREBF2	ENSG00000198911	-0.3615823928996319	[375]	[211,242,400,268]	-6	hSpCas9	negative selection	9517323
41875372	41875395	22	+	27260156	TC32	viability	TTACATCAAATACTTGCAGCAGG	SREBF2	ENSG00000198911	0.019017068282320332	[407]	[278,352,543,409]	0	hSpCas9	negative selection	9517324
41875328	41875351	22	+	27260156	TC32	viability	CCTACCCAGATGCACAAGTCTGG	SREBF2	ENSG00000198911	0.08693366285799192	[633]	[687,518,623,697]	1	hSpCas9	negative selection	9517325
41833252	41833275	22	+	27869803	HPAFII	viability after 27 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.679653625549366	[361]	[198,51,NaN]	-5	hSpCas9	negative selection	9581134
41867209	41867232	22	+	27869803	HPAFII	viability after 27 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.24742642840496443	[264]	[214,35,NaN]	-2	hSpCas9	negative selection	9581135
41868726	41868749	22	+	27869803	HPAFII	viability after 27 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.3951470047954996	[151]	[157,60,NaN]	3	hSpCas9	negative selection	9581136
41870885	41870908	22	-	27869803	HPAFII	viability after 27 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.475101596380173	[206]	[231,83,NaN]	4	hSpCas9	negative selection	9581137
41873782	41873805	22	+	27869803	HPAFII	viability after 27 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-1.273606359832495	[351]	[129,31,NaN]	-7	hSpCas9	negative selection	9581138
41875393	41875416	22	+	27869803	HPAFII	viability after 27 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-1.235609713037881	[67]	[12,16,NaN]	-7	hSpCas9	negative selection	9581139
41833252	41833275	22	+	27869803	HPAFII	viability after 15 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.4260660969075514	[361]	[468,177,NaN]	-5	hSpCas9	negative selection	9663583
41867209	41867232	22	+	27869803	HPAFII	viability after 15 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.7553434990879435	[264]	[193,152,NaN]	-7	hSpCas9	negative selection	9663584
41868726	41868749	22	+	27869803	HPAFII	viability after 15 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.4305581714940022	[151]	[406,103,NaN]	5	hSpCas9	negative selection	9663585
41870885	41870908	22	-	27869803	HPAFII	viability after 15 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.19498173179069217	[206]	[385,172,NaN]	2	hSpCas9	negative selection	9663586
41873782	41873805	22	+	27869803	HPAFII	viability after 15 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.42259870868765964	[351]	[584,93,NaN]	-5	hSpCas9	negative selection	9663587
41875393	41875416	22	+	27869803	HPAFII	viability after 15 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-1.6062622289880264	[67]	[60,0,NaN]	-8	hSpCas9	negative selection	9663588
41833252	41833275	22	+	27869803	ASPC1	viability after 36 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.6279130154754601	[552]	[159,290,397]	6	hSpCas9	negative selection	9746032
41867209	41867232	22	+	27869803	ASPC1	viability after 36 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.3864715883534128	[645]	[134,397,17]	-4	hSpCas9	negative selection	9746033
41868726	41868749	22	+	27869803	ASPC1	viability after 36 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	1.2630749443279767	[379]	[337,426,214]	9	hSpCas9	negative selection	9746034
41870885	41870908	22	-	27869803	ASPC1	viability after 36 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.6693109203032902	[618]	[57,140,184]	-6	hSpCas9	negative selection	9746035
41873782	41873805	22	+	27869803	ASPC1	viability after 36 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.3636819220694535	[908]	[114,372,235]	-4	hSpCas9	negative selection	9746036
41875393	41875416	22	+	27869803	ASPC1	viability after 36 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.7286357244274331	[175]	[310,0,33]	7	hSpCas9	negative selection	9746037
41833252	41833275	22	+	27869803	PATU8988S	viability after 35 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.24191178287739207	[438]	[154,143,NaN]	-3	hSpCas9	negative selection	9828481
41867209	41867232	22	+	27869803	PATU8988S	viability after 35 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.6891527450560365	[351]	[55,119,NaN]	-6	hSpCas9	negative selection	9828482
41868726	41868749	22	+	27869803	PATU8988S	viability after 35 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-1.059810826378278	[573]	[64,156,NaN]	-7	hSpCas9	negative selection	9828483
41870885	41870908	22	-	27869803	PATU8988S	viability after 35 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.8365780945856254	[584]	[102,160,NaN]	-7	hSpCas9	negative selection	9828484
41873782	41873805	22	+	27869803	PATU8988S	viability after 35 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-1.7749566840366988	[662]	[88,66,NaN]	-8	hSpCas9	negative selection	9828485
41875393	41875416	22	+	27869803	PATU8988S	viability after 35 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.5333529591207073	[137]	[53,106,NaN]	6	hSpCas9	negative selection	9828486
41833252	41833275	22	+	27869803	PATU8988S	viability after 31 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	0.43519953257164645	[438]	[248,220,NaN]	5	hSpCas9	negative selection	9910930
41867209	41867232	22	+	27869803	PATU8988S	viability after 31 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.25871837769693706	[351]	[93,146,NaN]	-3	hSpCas9	negative selection	9910931
41868726	41868749	22	+	27869803	PATU8988S	viability after 31 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-1.0026829069849243	[573]	[49,195,NaN]	-7	hSpCas9	negative selection	9910932
41870885	41870908	22	-	27869803	PATU8988S	viability after 31 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.42119100631154616	[584]	[193,148,NaN]	-5	hSpCas9	negative selection	9910933
41873782	41873805	22	+	27869803	PATU8988S	viability after 31 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-1.1011464814333454	[662]	[91,162,NaN]	-8	hSpCas9	negative selection	9910934
41875393	41875416	22	+	27869803	PATU8988S	viability after 31 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	0.37733357351376284	[137]	[52,94,NaN]	4	hSpCas9	negative selection	9910935
41833252	41833275	22	+	27869803	HPAFII	viability after 35 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.6928929023505656	[361]	[142,79,NaN]	-4	hSpCas9	negative selection	9993379
41867209	41867232	22	+	27869803	HPAFII	viability after 35 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	0.5467461778592064	[264]	[258,124,NaN]	3	hSpCas9	negative selection	9993380
41868726	41868749	22	+	27869803	HPAFII	viability after 35 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	0.10631205389374754	[151]	[103,58,NaN]	0	hSpCas9	negative selection	9993381
41870885	41870908	22	-	27869803	HPAFII	viability after 35 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	0.10539554934732481	[206]	[171,45,NaN]	0	hSpCas9	negative selection	9993382
41873782	41873805	22	+	27869803	HPAFII	viability after 35 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.4639955636105069	[351]	[155,98,NaN]	-3	hSpCas9	negative selection	9993383
41875393	41875416	22	+	27869803	HPAFII	viability after 35 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-1.5860332827499772	[67]	[2,20,NaN]	-7	hSpCas9	negative selection	9993384
41833252	41833275	22	+	27869803	HPAFII	viability after 31 days	TTCTGCGCTGAGCCGGGCGATGG	SREBF2	ENSG00000198911	-0.7328683291071674	[361]	[216,18,NaN]	-5	hSpCas9	negative selection	10075828
41867209	41867232	22	+	27869803	HPAFII	viability after 31 days	TCAGCACCACTCCGCAGACGAGG	SREBF2	ENSG00000198911	-0.0614423104106505	[264]	[209,68,NaN]	0	hSpCas9	negative selection	10075829
41868726	41868749	22	+	27869803	HPAFII	viability after 31 days	CACGCTGCAGACCCTTGCCCCGG	SREBF2	ENSG00000198911	-0.3381987878567283	[151]	[66,67,NaN]	-2	hSpCas9	negative selection	10075830
41870885	41870908	22	-	27869803	HPAFII	viability after 31 days	TCTGAGGCTGGACCAGGACCTGG	SREBF2	ENSG00000198911	-0.17341514811630837	[206]	[147,53,NaN]	-1	hSpCas9	negative selection	10075831
41873782	41873805	22	+	27869803	HPAFII	viability after 31 days	CCTGTCCCTATTCTAGACCCTGG	SREBF2	ENSG00000198911	-0.632434574809646	[351]	[192,55,NaN]	-4	hSpCas9	negative selection	10075832
41875393	41875416	22	+	27869803	HPAFII	viability after 31 days	GGTCAATCATAAACTGCGCCAGG	SREBF2	ENSG00000198911	-0.8975453498181434	[67]	[8,32,NaN]	-5	hSpCas9	negative selection	10075833
41866973	41866996	22	+	28162770	P31FUJ	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-2.554730299301741	[64]	[12]	-8	hSpCas9	negative selection	10242867
41833270	41833293	22	+	28162770	P31FUJ	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.13063409837725282	[184]	[237]	1	hSpCas9	negative selection	10242868
41875568	41875591	22	+	28162770	P31FUJ	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.8297392616543343	[78]	[164]	8	hSpCas9	negative selection	10242869
41878009	41878032	22	-	28162770	P31FUJ	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.6726228046231109	[136]	[100]	-5	hSpCas9	negative selection	10242870
41884897	41884920	22	+	28162770	P31FUJ	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.7641379958365634	[235]	[470]	8	hSpCas9	negative selection	10242871
41884970	41884993	22	+	28162770	P31FUJ	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-1.5353649744348097	[36]	[14]	-7	hSpCas9	negative selection	10242872
41893178	41893201	22	-	28162770	P31FUJ	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-1.6596168714695758	[163]	[60]	-8	hSpCas9	negative selection	10242873
41894842	41894865	22	-	28162770	P31FUJ	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	-0.14676237334768716	[178]	[189]	-1	hSpCas9	negative selection	10242874
41900450	41900473	22	+	28162770	P31FUJ	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.34242669558887673	[163]	[151]	-3	hSpCas9	negative selection	10242875
41900473	41900496	22	-	28162770	P31FUJ	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-3.6434981565079934	[552]	[51]	-9	hSpCas9	negative selection	10242876
41866973	41866996	22	+	28162770	TF1	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10412233
41833270	41833293	22	+	28162770	TF1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10412234
41875568	41875591	22	+	28162770	TF1	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10412235
41878009	41878032	22	-	28162770	TF1	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10412236
41884897	41884920	22	+	28162770	TF1	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	NaN	[NaN]	[412]	1	hSpCas9	negative selection	10412237
41884970	41884993	22	+	28162770	TF1	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10412238
41893178	41893201	22	-	28162770	TF1	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10412239
41894842	41894865	22	-	28162770	TF1	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10412240
41900450	41900473	22	+	28162770	TF1	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	NaN	[NaN]	[345]	1	hSpCas9	negative selection	10412241
41900473	41900496	22	-	28162770	TF1	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10412242
41866973	41866996	22	+	28162770	SKM1	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-0.2694606749932269	[14]	[21]	-2	hSpCas9	negative selection	10581599
41833270	41833293	22	+	28162770	SKM1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.5930358012568383	[26]	[71]	6	hSpCas9	negative selection	10581600
41875568	41875591	22	+	28162770	SKM1	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-1.5875364443849824	[33]	[19]	-8	hSpCas9	negative selection	10581601
41878009	41878032	22	-	28162770	SKM1	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.009087250622500709	[36]	[64]	0	hSpCas9	negative selection	10581602
41884897	41884920	22	+	28162770	SKM1	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.296910653278248	[81]	[117]	-3	hSpCas9	negative selection	10581603
41884970	41884993	22	+	28162770	SKM1	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.8333501305905486	[19]	[62]	7	hSpCas9	negative selection	10581604
41893178	41893201	22	-	28162770	SKM1	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-2.102109617214741	[33]	[13]	-8	hSpCas9	negative selection	10581605
41894842	41894865	22	-	28162770	SKM1	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	1.4721814063824525	[41]	[205]	9	hSpCas9	negative selection	10581606
41900450	41900473	22	+	28162770	SKM1	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10581607
41900473	41900496	22	-	28162770	SKM1	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.2179303743531444	[149]	[56]	-8	hSpCas9	negative selection	10581608
41866973	41866996	22	+	28162770	SKM1	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-0.2694606749932269	[14]	[21]	-2	hSpCas9	negative selection	10750965
41833270	41833293	22	+	28162770	SKM1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.5930358012568383	[26]	[71]	6	hSpCas9	negative selection	10750966
41875568	41875591	22	+	28162770	SKM1	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-1.5875364443849824	[33]	[19]	-8	hSpCas9	negative selection	10750967
41878009	41878032	22	-	28162770	SKM1	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.009087250622500709	[36]	[64]	0	hSpCas9	negative selection	10750968
41884897	41884920	22	+	28162770	SKM1	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.296910653278248	[81]	[117]	-3	hSpCas9	negative selection	10750969
41884970	41884993	22	+	28162770	SKM1	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.8333501305905486	[19]	[62]	7	hSpCas9	negative selection	10750970
41893178	41893201	22	-	28162770	SKM1	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-2.102109617214741	[33]	[13]	-8	hSpCas9	negative selection	10750971
41894842	41894865	22	-	28162770	SKM1	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	1.4721814063824525	[41]	[205]	9	hSpCas9	negative selection	10750972
41900450	41900473	22	+	28162770	SKM1	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10750973
41900473	41900496	22	-	28162770	SKM1	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.2179303743531444	[149]	[56]	-8	hSpCas9	negative selection	10750974
41866973	41866996	22	+	28162770	PL21	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-3.814810726976652	[96]	[2]	-9	hSpCas9	negative selection	10920331
41833270	41833293	22	+	28162770	PL21	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.3851715083218409	[94]	[53]	3	hSpCas9	negative selection	10920332
41875568	41875591	22	+	28162770	PL21	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-0.7540566958975552	[92]	[23]	-5	hSpCas9	negative selection	10920333
41878009	41878032	22	-	28162770	PL21	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-1.4661229883336842	[145]	[22]	-7	hSpCas9	negative selection	10920334
41884897	41884920	22	+	28162770	PL21	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.8525018652519096	[306]	[73]	-5	hSpCas9	negative selection	10920335
41884970	41884993	22	+	28162770	PL21	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-0.4075429627319196	[63]	[20]	-3	hSpCas9	negative selection	10920336
41893178	41893201	22	-	28162770	PL21	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-1.5368259796768862	[139]	[20]	-7	hSpCas9	negative selection	10920337
41894842	41894865	22	-	28162770	PL21	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.6614707660420989	[137]	[94]	6	hSpCas9	negative selection	10920338
41900450	41900473	22	+	28162770	PL21	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.246116615400244	[108]	[39]	-2	hSpCas9	negative selection	10920339
41900473	41900496	22	-	28162770	PL21	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-1.6106462129685575	[420]	[59]	-8	hSpCas9	negative selection	10920340
41866973	41866996	22	+	28162770	P31FUJ	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-2.554730299301741	[64]	[12]	-8	hSpCas9	negative selection	11089697
41833270	41833293	22	+	28162770	P31FUJ	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.13063409837725282	[184]	[237]	1	hSpCas9	negative selection	11089698
41875568	41875591	22	+	28162770	P31FUJ	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.8297392616543343	[78]	[164]	8	hSpCas9	negative selection	11089699
41878009	41878032	22	-	28162770	P31FUJ	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.6726228046231109	[136]	[100]	-5	hSpCas9	negative selection	11089700
41884897	41884920	22	+	28162770	P31FUJ	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.7641379958365634	[235]	[470]	8	hSpCas9	negative selection	11089701
41884970	41884993	22	+	28162770	P31FUJ	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-1.5353649744348097	[36]	[14]	-7	hSpCas9	negative selection	11089702
41893178	41893201	22	-	28162770	P31FUJ	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-1.6596168714695758	[163]	[60]	-8	hSpCas9	negative selection	11089703
41894842	41894865	22	-	28162770	P31FUJ	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	-0.14676237334768716	[178]	[189]	-1	hSpCas9	negative selection	11089704
41900450	41900473	22	+	28162770	P31FUJ	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.34242669558887673	[163]	[151]	-3	hSpCas9	negative selection	11089705
41900473	41900496	22	-	28162770	P31FUJ	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-3.6434981565079934	[552]	[51]	-9	hSpCas9	negative selection	11089706
41866973	41866996	22	+	28162770	OCIAML5	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-1.4370290715851535	[35]	[23]	-7	hSpCas9	negative selection	11259063
41833270	41833293	22	+	28162770	OCIAML5	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.8470024155436808	[80]	[262]	7	hSpCas9	negative selection	11259064
41875568	41875591	22	+	28162770	OCIAML5	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-1.35902655958388	[53]	[37]	-7	hSpCas9	negative selection	11259065
41878009	41878032	22	-	28162770	OCIAML5	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	0.8359894228212627	[62]	[202]	7	hSpCas9	negative selection	11259066
41884897	41884920	22	+	28162770	OCIAML5	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.30436258809409233	[178]	[398]	2	hSpCas9	negative selection	11259067
41884970	41884993	22	+	28162770	OCIAML5	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.3495672903056537	[29]	[68]	3	hSpCas9	negative selection	11259068
41893178	41893201	22	-	28162770	OCIAML5	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.7350271496737775	[70]	[76]	-5	hSpCas9	negative selection	11259069
41894842	41894865	22	-	28162770	OCIAML5	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.2741105352131478	[92]	[202]	2	hSpCas9	negative selection	11259070
41900450	41900473	22	+	28162770	OCIAML5	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	0.040018089969115316	[110]	[205]	0	hSpCas9	negative selection	11259071
41900473	41900496	22	-	28162770	OCIAML5	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-3.5035966885241425	[376]	[59]	-9	hSpCas9	negative selection	11259072
41866973	41866996	22	+	28162770	EOL1	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-1.2875027055444541	[138]	[29]	-7	hSpCas9	negative selection	11428429
41833270	41833293	22	+	28162770	EOL1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.9435308749381075	[150]	[152]	7	hSpCas9	negative selection	11428430
41875568	41875591	22	+	28162770	EOL1	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-0.3847802865371943	[113]	[45]	-3	hSpCas9	negative selection	11428431
41878009	41878032	22	-	28162770	EOL1	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	0.6946216775486791	[223]	[190]	6	hSpCas9	negative selection	11428432
41884897	41884920	22	+	28162770	EOL1	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.10588412464342589	[526]	[257]	-1	hSpCas9	negative selection	11428433
41884970	41884993	22	+	28162770	EOL1	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-0.1299000124518419	[80]	[38]	-1	hSpCas9	negative selection	11428434
41893178	41893201	22	-	28162770	EOL1	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.940522648343357	[152]	[41]	-6	hSpCas9	negative selection	11428435
41894842	41894865	22	-	28162770	EOL1	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	-1.3336044128835132	[176]	[36]	-7	hSpCas9	negative selection	11428436
41900450	41900473	22	+	28162770	EOL1	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	1.0850124437637807	[152]	[170]	8	hSpCas9	negative selection	11428437
41900473	41900496	22	-	28162770	EOL1	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-1.149322125055825	[580]	[137]	-6	hSpCas9	negative selection	11428438
41866973	41866996	22	+	28162770	MOLM13	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-1.093989506063536	[123]	[41]	-5	hSpCas9	negative selection	11597795
41833270	41833293	22	+	28162770	MOLM13	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	-0.05178165892485831	[161]	[112]	0	hSpCas9	negative selection	11597796
41875568	41875591	22	+	28162770	MOLM13	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-0.3541123164774267	[98]	[55]	-2	hSpCas9	negative selection	11597797
41878009	41878032	22	-	28162770	MOLM13	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	1.2721649106702109	[200]	[350]	8	hSpCas9	negative selection	11597798
41884897	41884920	22	+	28162770	MOLM13	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.7184818086962544	[426]	[507]	5	hSpCas9	negative selection	11597799
41884970	41884993	22	+	28162770	MOLM13	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	2.061730033612188	[53]	[162]	9	hSpCas9	negative selection	11597800
41893178	41893201	22	-	28162770	MOLM13	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.22016661214068078	[144]	[89]	-1	hSpCas9	negative selection	11597801
41894842	41894865	22	-	28162770	MOLM13	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.7222065702772638	[165]	[197]	5	hSpCas9	negative selection	11597802
41900450	41900473	22	+	28162770	MOLM13	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	1.0423135224718072	[228]	[340]	7	hSpCas9	negative selection	11597803
41900473	41900496	22	-	28162770	MOLM13	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-3.5158350787425907	[616]	[38]	-8	hSpCas9	negative selection	11597804
41866973	41866996	22	+	28162770	HEL	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-2.2913732323431857	[106]	[13]	-8	hSpCas9	negative selection	11767161
41833270	41833293	22	+	28162770	HEL	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	-0.025810298993774183	[150]	[94]	0	hSpCas9	negative selection	11767162
41875568	41875591	22	+	28162770	HEL	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.5335097622455985	[95]	[88]	4	hSpCas9	negative selection	11767163
41878009	41878032	22	-	28162770	HEL	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	0.2374823535140987	[146]	[110]	2	hSpCas9	negative selection	11767164
41884897	41884920	22	+	28162770	HEL	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.08815224775616493	[394]	[237]	0	hSpCas9	negative selection	11767165
41884970	41884993	22	+	28162770	HEL	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-0.25034596408313115	[64]	[34]	-2	hSpCas9	negative selection	11767166
41893178	41893201	22	-	28162770	HEL	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-0.29479708105298963	[112]	[58]	-2	hSpCas9	negative selection	11767167
41894842	41894865	22	-	28162770	HEL	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.19182429639291637	[189]	[138]	1	hSpCas9	negative selection	11767168
41900450	41900473	22	+	28162770	HEL	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.13075263819096322	[199]	[116]	-1	hSpCas9	negative selection	11767169
41900473	41900496	22	-	28162770	HEL	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-5.31404063940052	[558]	[8]	-9	hSpCas9	negative selection	11767170
41866973	41866996	22	+	28162770	MV411	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-4.7525624492172245	[95]	[2]	-9	hSpCas9	negative selection	11936527
41833270	41833293	22	+	28162770	MV411	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.462031601558816	[105]	[122]	4	hSpCas9	negative selection	11936528
41875568	41875591	22	+	28162770	MV411	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.4660778372581158	[54]	[63]	4	hSpCas9	negative selection	11936529
41878009	41878032	22	-	28162770	MV411	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.44372435377030595	[154]	[95]	-3	hSpCas9	negative selection	11936530
41884897	41884920	22	+	28162770	MV411	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.32221189444387677	[327]	[220]	-2	hSpCas9	negative selection	11936531
41884970	41884993	22	+	28162770	MV411	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.0869728785895294	[56]	[50]	0	hSpCas9	negative selection	11936532
41893178	41893201	22	-	28162770	MV411	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	0.6235860366680241	[93]	[121]	5	hSpCas9	negative selection	11936533
41894842	41894865	22	-	28162770	MV411	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.37029429856830876	[134]	[146]	3	hSpCas9	negative selection	11936534
41900450	41900473	22	+	28162770	MV411	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.23516323230870317	[101]	[72]	-2	hSpCas9	negative selection	11936535
41900473	41900496	22	-	28162770	MV411	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.2463001898918424	[382]	[67]	-8	hSpCas9	negative selection	11936536
41866973	41866996	22	+	28162770	MONOMAC1	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-1.5690056244465116	[43]	[16]	-8	hSpCas9	negative selection	12105893
41833270	41833293	22	+	28162770	MONOMAC1	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	-0.27949900725152643	[53]	[50]	-2	hSpCas9	negative selection	12105894
41875568	41875591	22	+	28162770	MONOMAC1	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	-1.5036981852936055	[46]	[18]	-8	hSpCas9	negative selection	12105895
41878009	41878032	22	-	28162770	MONOMAC1	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	-0.06726897208922411	[84]	[92]	0	hSpCas9	negative selection	12105896
41884897	41884920	22	+	28162770	MONOMAC1	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	-0.13932134920326622	[195]	[203]	-1	hSpCas9	negative selection	12105897
41884970	41884993	22	+	28162770	MONOMAC1	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-1.1563948625622076	[34]	[17]	-7	hSpCas9	negative selection	12105898
41893178	41893201	22	-	28162770	MONOMAC1	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-1.3316863737543354	[100]	[45]	-7	hSpCas9	negative selection	12105899
41894842	41894865	22	-	28162770	MONOMAC1	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	-1.4600712528933475	[95]	[39]	-8	hSpCas9	negative selection	12105900
41900450	41900473	22	+	28162770	MONOMAC1	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.0642816382077821	[82]	[90]	0	hSpCas9	negative selection	12105901
41900473	41900496	22	-	28162770	MONOMAC1	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-1.3810370337135889	[308]	[135]	-8	hSpCas9	negative selection	12105902
41866973	41866996	22	+	28162770	OCIAML2	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-4.248237403905714	[23]	[6]	-9	hSpCas9	negative selection	12275259
41833270	41833293	22	+	28162770	OCIAML2	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	0.6698513983076693	[10]	[96]	6	hSpCas9	negative selection	12275260
41875568	41875591	22	+	28162770	OCIAML2	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.814772393620087	[11]	[116]	7	hSpCas9	negative selection	12275261
41878009	41878032	22	-	28162770	OCIAML2	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	0.5443205162238103	[23]	[193]	5	hSpCas9	negative selection	12275262
41884897	41884920	22	+	28162770	OCIAML2	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.8934237453178776	[53]	[555]	8	hSpCas9	negative selection	12275263
41884970	41884993	22	+	28162770	OCIAML2	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	-0.6930222465786091	[13]	[47]	-5	hSpCas9	negative selection	12275264
41893178	41893201	22	-	28162770	OCIAML2	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	-2.055592325963317	[17]	[23]	-8	hSpCas9	negative selection	12275265
41894842	41894865	22	-	28162770	OCIAML2	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	1.7257673875613424	[20]	[384]	9	hSpCas9	negative selection	12275266
41900450	41900473	22	+	28162770	OCIAML2	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	0.08518632981947838	[24]	[146]	0	hSpCas9	negative selection	12275267
41900473	41900496	22	-	28162770	OCIAML2	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-2.3551526078222254	[59]	[64]	-8	hSpCas9	negative selection	12275268
41866973	41866996	22	+	28162770	OCIAML3	viability	GGGCAGCAGCAGCGGAGCTGTGG	SREBF2	ENSG00000198911	-2.387556762856737	[25]	[14]	-9	hSpCas9	negative selection	12444625
41833270	41833293	22	+	28162770	OCIAML3	viability	GATGGACGACAGCGGCGAGCTGG	SREBF2	ENSG00000198911	1.128458384146928	[29]	[197]	8	hSpCas9	negative selection	12444626
41875568	41875591	22	+	28162770	OCIAML3	viability	CAGTCTGGTGGACAATGAGGTGG	SREBF2	ENSG00000198911	0.17152710603881371	[19]	[67]	1	hSpCas9	negative selection	12444627
41878009	41878032	22	-	28162770	OCIAML3	viability	GCAGCTTCACAAAGACGCTCAGG	SREBF2	ENSG00000198911	0.4357397030698889	[35]	[146]	4	hSpCas9	negative selection	12444628
41884897	41884920	22	+	28162770	OCIAML3	viability	GAACCTGGCTGAATGTGCAGAGG	SREBF2	ENSG00000198911	0.2804614775919779	[65]	[241]	2	hSpCas9	negative selection	12444629
41884970	41884993	22	+	28162770	OCIAML3	viability	GGGCTCAAGACCCGGTGTGGAGG	SREBF2	ENSG00000198911	0.33887816381729996	[10]	[41]	3	hSpCas9	negative selection	12444630
41893178	41893201	22	-	28162770	OCIAML3	viability	GGGGTGGCAGAGCCAGCGCAGGG	SREBF2	ENSG00000198911	0.05806905625553016	[27]	[87]	0	hSpCas9	negative selection	12444631
41894842	41894865	22	-	28162770	OCIAML3	viability	GCAGGTTCTTGCAGAAGGCCTGG	SREBF2	ENSG00000198911	0.03921002900421401	[48]	[151]	0	hSpCas9	negative selection	12444632
41900450	41900473	22	+	28162770	OCIAML3	viability	GAGCAGCCTCAACGTCAGTGGGG	SREBF2	ENSG00000198911	-0.4033240787150535	[45]	[104]	-3	hSpCas9	negative selection	12444633
41900473	41900496	22	-	28162770	OCIAML3	viability	GTTGAGGGCAGGGTCAGAGGTGG	SREBF2	ENSG00000198911	-1.9189697953011589	[118]	[94]	-8	hSpCas9	negative selection	12444634