Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 6789
  • Symbol: STK4
  • Description: serine/threonine kinase 4
DataSource: http://genomecrispr.dkfz.de/#!/results/STK4

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
45000468 45000491 20 + 26472758 Jiyoye viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.09936047225846645 [178] [125] 0 hSpCas9 negative selection 158098
44995116 44995139 20 + 26472758 Jiyoye viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 1.3620874919773354 [64] [125] 7 hSpCas9 negative selection 158099
45025095 45025118 20 + 26472758 Jiyoye viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.03996640731764467 [177] [137] 0 hSpCas9 negative selection 158100
44972136 44972159 20 + 26472758 Jiyoye viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 2.2961440691171298 [53] [199] 9 hSpCas9 negative selection 158101
44997193 44997216 20 - 26472758 Jiyoye viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.10761509964696556 [95] [77] 0 hSpCas9 negative selection 158102
44997260 44997283 20 + 26472758 Jiyoye viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.9067463909963849 [86] [122] 6 hSpCas9 negative selection 158103
44995194 44995217 20 + 26472758 Jiyoye viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.19305057615302612 [28] [24] 1 hSpCas9 negative selection 158104
45001304 45001327 20 + 26472758 Jiyoye viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.374459806362495 [222] [217] 3 hSpCas9 negative selection 158105
45025038 45025061 20 + 26472758 Jiyoye viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.4001795405517308 [55] [31] -3 hSpCas9 negative selection 158106
44966567 44966590 20 + 26472758 Jiyoye viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.608421473545145 [92] [45] -4 hSpCas9 negative selection 158107
45000468 45000491 20 + 26472758 KBM7 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.09834323258595778 [429,338] [211,127] -1 hSpCas9 negative selection 349216
44995116 44995139 20 + 26472758 KBM7 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.5391042485097892 [443,504] [395,266] 6 hSpCas9 negative selection 349217
45025095 45025118 20 + 26472758 KBM7 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.38065131985664724 [492,360] [170,135] -3 hSpCas9 negative selection 349218
44972136 44972159 20 + 26472758 KBM7 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.04525119485608209 [652,490] [349,175] 0 hSpCas9 negative selection 349219
44997193 44997216 20 - 26472758 KBM7 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.39905234763021225 [360,283] [245,155] 4 hSpCas9 negative selection 349220
44997260 44997283 20 + 26472758 KBM7 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.0012292287547117642 [339,188] [163,82] 0 hSpCas9 negative selection 349221
44995194 44995217 20 + 26472758 KBM7 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.6570643406875551 [188,181] [157,119] 7 hSpCas9 negative selection 349222
45001304 45001327 20 + 26472758 KBM7 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.06279178940514751 [960,1015] [560,424] 0 hSpCas9 negative selection 349223
45025038 45025061 20 + 26472758 KBM7 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.05040910541483301 [318,314] [154,154] 0 hSpCas9 negative selection 349224
44966567 44966590 20 + 26472758 KBM7 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 0.30751451986111156 [639,614] [362,368] 3 hSpCas9 negative selection 349225
45000468 45000491 20 + 26472758 Raji viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.02898890635768639 [254] [57] 0 hSpCas9 negative selection 540334
44995116 44995139 20 + 26472758 Raji viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 -0.45103717789506476 [376] [63] -4 hSpCas9 negative selection 540335
45025095 45025118 20 + 26472758 Raji viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.15940300532130192 [230] [47] -1 hSpCas9 negative selection 540336
44972136 44972159 20 + 26472758 Raji viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -1.250168469244484 [409] [39] -7 hSpCas9 negative selection 540337
44997193 44997216 20 - 26472758 Raji viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 -0.05951377337114478 [237] [52] 0 hSpCas9 negative selection 540338
44997260 44997283 20 + 26472758 Raji viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.5444473409824422 [194] [65] 5 hSpCas9 negative selection 540339
44995194 44995217 20 + 26472758 Raji viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.5663882323054125 [133] [20] -4 hSpCas9 negative selection 540340
45001304 45001327 20 + 26472758 Raji viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.6006157650326417 [394] [138] 5 hSpCas9 negative selection 540341
45025038 45025061 20 + 26472758 Raji viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 1.2104770283377029 [107] [57] 9 hSpCas9 negative selection 540342
44966567 44966590 20 + 26472758 Raji viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -1.4035783839037799 [284] [24] -7 hSpCas9 negative selection 540343
45000468 45000491 20 + 26472758 K562 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.6645167939270961 [352] [187] -4 hSpCas9 negative selection 731452
44995116 44995139 20 + 26472758 K562 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 1.9375300322432256 [333] [1079] 9 hSpCas9 negative selection 731453
45025095 45025118 20 + 26472758 K562 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.3928987545477997 [368] [408] 3 hSpCas9 negative selection 731454
44972136 44972159 20 + 26472758 K562 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.042352921807299104 [526] [431] 0 hSpCas9 negative selection 731455
44997193 44997216 20 - 26472758 K562 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 -0.46210575293562256 [296] [181] -3 hSpCas9 negative selection 731456
44997260 44997283 20 + 26472758 K562 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.9350906695587181 [284] [459] 7 hSpCas9 negative selection 731457
44995194 44995217 20 + 26472758 K562 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 1.2096533095057702 [146] [286] 8 hSpCas9 negative selection 731458
45001304 45001327 20 + 26472758 K562 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.23007928839392688 [909] [900] 1 hSpCas9 negative selection 731459
45025038 45025061 20 + 26472758 K562 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.14196856685565135 [348] [266] -1 hSpCas9 negative selection 731460
44966567 44966590 20 + 26472758 K562 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.9017608233360299 [466] [210] -5 hSpCas9 negative selection 731461
44966556 44966579 20 + 26627737 DLD1 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.4176486843293482 [564] [134,195,76] -4 hSpCas9 negative selection 814723
44987207 44987230 20 + 26627737 DLD1 viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.39939793377970667 [212] [38,50,59] -4 hSpCas9 negative selection 814724
45000454 45000477 20 + 26627737 DLD1 viability GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.8712999947498088 [66] [17,116,93] 9 hSpCas9 negative selection 814725
45001199 45001222 20 + 26627737 DLD1 viability TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.22061958709554097 [778] [228,251,155] -2 hSpCas9 negative selection 814726
45053145 45053168 20 - 26627737 DLD1 viability AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.16928905517018744 [645] [182,288,85] -2 hSpCas9 negative selection 814727
45075100 45075123 20 + 26627737 DLD1 viability GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -1.0213541836720244 [240] [97,16,0] -7 hSpCas9 negative selection 814728
44966556 44966579 20 + 26627737 GBM cells viability after 5 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.7712959124539817 [365] [83,145] -8 hSpCas9 negative selection 897038
44987207 44987230 20 + 26627737 GBM cells viability after 5 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.5668809023619279 [196] [137,174] 7 hSpCas9 negative selection 897039
45000454 45000477 20 + 26627737 GBM cells viability after 5 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.1408866651916498 [114] [184,86] 9 hSpCas9 negative selection 897040
45001199 45001222 20 + 26627737 GBM cells viability after 5 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.09652784315201007 [315] [148,167] -1 hSpCas9 negative selection 897041
45053145 45053168 20 - 26627737 GBM cells viability after 5 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.24947796500698546 [265] [119,119] -4 hSpCas9 negative selection 897042
45075100 45075123 20 + 26627737 GBM cells viability after 5 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.33354210252241023 [127] [66,105] 5 hSpCas9 negative selection 897043
44966556 44966579 20 + 26627737 GBM cells viability after 13 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.0196447876243084 [365] [135,66] -8 hSpCas9 negative selection 979353
44987207 44987230 20 + 26627737 GBM cells viability after 13 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.57646595037668 [196] [181,140] 7 hSpCas9 negative selection 979354
45000454 45000477 20 + 26627737 GBM cells viability after 13 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.6653266371911615 [114] [152,54] 7 hSpCas9 negative selection 979355
45001199 45001222 20 + 26627737 GBM cells viability after 13 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.09749607773053132 [315] [167,195] 1 hSpCas9 negative selection 979356
45053145 45053168 20 - 26627737 GBM cells viability after 13 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.15416100047962433 [265] [148,113] -2 hSpCas9 negative selection 979357
45075100 45075123 20 + 26627737 GBM cells viability after 13 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.015169764619408 [127] [94,49] 0 hSpCas9 negative selection 979358
44966556 44966579 20 + 26627737 GBM cells viability after 21 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.1432572653116222 [365] [112,68] -7 hSpCas9 negative selection 1061668
44987207 44987230 20 + 26627737 GBM cells viability after 21 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.9419558990171905 [196] [202,207] 8 hSpCas9 negative selection 1061669
45000454 45000477 20 + 26627737 GBM cells viability after 21 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.369041367141816 [114] [87,73] 4 hSpCas9 negative selection 1061670
45001199 45001222 20 + 26627737 GBM cells viability after 21 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.46092837052504015 [315] [240,231] 5 hSpCas9 negative selection 1061671
45053145 45053168 20 - 26627737 GBM cells viability after 21 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.174798689735976 [265] [150,106] -1 hSpCas9 negative selection 1061672
45075100 45075123 20 + 26627737 GBM cells viability after 21 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -2.1348735927745497 [127] [7,22] -9 hSpCas9 negative selection 1061673
44966556 44966579 20 + 26627737 RPE1 viability after 9 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.6294132707577111 [1373] [250,312] -4 hSpCas9 negative selection 1143983
44987207 44987230 20 + 26627737 RPE1 viability after 9 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.6952162328860139 [772] [162,131] -5 hSpCas9 negative selection 1143984
45000454 45000477 20 + 26627737 RPE1 viability after 9 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -1.1378033120502935 [600] [119,40] -7 hSpCas9 negative selection 1143985
45001199 45001222 20 + 26627737 RPE1 viability after 9 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.6930822176899967 [993] [496,510] 4 hSpCas9 negative selection 1143986
45053145 45053168 20 - 26627737 RPE1 viability after 9 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.4275473011825908 [448] [216,152] 3 hSpCas9 negative selection 1143987
45075100 45075123 20 + 26627737 RPE1 viability after 9 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.4637717173463271 [912] [53,404] -3 hSpCas9 negative selection 1143988
44966556 44966579 20 + 26627737 RPE1 viability after 12 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.8449600053230362 [1373] [273,132] -5 hSpCas9 negative selection 1226298
44987207 44987230 20 + 26627737 RPE1 viability after 12 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.09448088751071343 [772] [126,265] 0 hSpCas9 negative selection 1226299
45000454 45000477 20 + 26627737 RPE1 viability after 12 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.5597581643148632 [600] [144,71] -4 hSpCas9 negative selection 1226300
45001199 45001222 20 + 26627737 RPE1 viability after 12 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.4868954108820001 [993] [365,382] 3 hSpCas9 negative selection 1226301
45053145 45053168 20 - 26627737 RPE1 viability after 12 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.37226254054629176 [448] [143,168] 2 hSpCas9 negative selection 1226302
45075100 45075123 20 + 26627737 RPE1 viability after 12 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.3165170718887812 [912] [76,323] -2 hSpCas9 negative selection 1226303
44966556 44966579 20 + 26627737 RPE1 viability after 15 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.7347473259821032 [1373] [229,236] -5 hSpCas9 negative selection 1308613
44987207 44987230 20 + 26627737 RPE1 viability after 15 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.18635577135386397 [772] [238,146] -1 hSpCas9 negative selection 1308614
45000454 45000477 20 + 26627737 RPE1 viability after 15 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.38124119589261884 [600] [156,104] -2 hSpCas9 negative selection 1308615
45001199 45001222 20 + 26627737 RPE1 viability after 15 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.8563866904810546 [993] [560,458] 5 hSpCas9 negative selection 1308616
45053145 45053168 20 - 26627737 RPE1 viability after 15 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.3208130553862167 [448] [469,169] 7 hSpCas9 negative selection 1308617
45075100 45075123 20 + 26627737 RPE1 viability after 15 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.5097599072873875 [912] [74,283] -3 hSpCas9 negative selection 1308618
44966556 44966579 20 + 26627737 RPE1 viability after 18 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.5861031155470142 [1373] [217,277] -4 hSpCas9 negative selection 1390928
44987207 44987230 20 + 26627737 RPE1 viability after 18 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.8172696760359704 [772] [85,152] -5 hSpCas9 negative selection 1390929
45000454 45000477 20 + 26627737 RPE1 viability after 18 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.9192688953278075 [600] [107,61] -5 hSpCas9 negative selection 1390930
45001199 45001222 20 + 26627737 RPE1 viability after 18 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.6860602407279546 [993] [331,537] 4 hSpCas9 negative selection 1390931
45053145 45053168 20 - 26627737 RPE1 viability after 18 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.1332218909815341 [448] [244,287] 6 hSpCas9 negative selection 1390932
45075100 45075123 20 + 26627737 RPE1 viability after 18 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.6510968899908074 [912] [51,268] -4 hSpCas9 negative selection 1390933
44966556 44966579 20 + 26627737 HeLa viability after 8 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.1841484474744162 [788] [190,133,137] -8 hSpCas9 negative selection 1473243
44987207 44987230 20 + 26627737 HeLa viability after 8 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.9015220751389149 [186] [145,190,119] 7 hSpCas9 negative selection 1473244
45000454 45000477 20 + 26627737 HeLa viability after 8 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.08463329876831427 [230] [21,199,80] 0 hSpCas9 negative selection 1473245
45001199 45001222 20 + 26627737 HeLa viability after 8 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.08447558633739582 [671] [191,312,301] -1 hSpCas9 negative selection 1473246
45053145 45053168 20 - 26627737 HeLa viability after 8 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.6213053402491242 [270] [240,248,74] 5 hSpCas9 negative selection 1473247
45075100 45075123 20 + 26627737 HeLa viability after 8 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -1.6787041438723451 [320] [68,1,63] -9 hSpCas9 negative selection 1473248
44966556 44966579 20 + 26627737 HeLa viability after 12 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.4458179402154374 [788] [135,39,191] -8 hSpCas9 negative selection 1555558
44987207 44987230 20 + 26627737 HeLa viability after 12 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.42548917251135787 [186] [112,156,35] 3 hSpCas9 negative selection 1555559
45000454 45000477 20 + 26627737 HeLa viability after 12 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.8392307729023507 [230] [14,52,90] -6 hSpCas9 negative selection 1555560
45001199 45001222 20 + 26627737 HeLa viability after 12 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.059480206132947244 [671] [284,242,344] 0 hSpCas9 negative selection 1555561
45053145 45053168 20 - 26627737 HeLa viability after 12 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.067410339511473 [270] [394,90,237] 7 hSpCas9 negative selection 1555562
45075100 45075123 20 + 26627737 HeLa viability after 12 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -1.5966074634421203 [320] [23,43,62] -9 hSpCas9 negative selection 1555563
44966556 44966579 20 + 26627737 HeLa viability after 15 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.4504058212822988 [788] [100,119,132] -8 hSpCas9 negative selection 1637873
44987207 44987230 20 + 26627737 HeLa viability after 15 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.014033184897775941 [186] [14,135,75] 0 hSpCas9 negative selection 1637874
45000454 45000477 20 + 26627737 HeLa viability after 15 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -2.4318396268922005 [230] [0,27,23] -9 hSpCas9 negative selection 1637875
45001199 45001222 20 + 26627737 HeLa viability after 15 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.4034662917315648 [671] [198,425,470] 3 hSpCas9 negative selection 1637876
45053145 45053168 20 - 26627737 HeLa viability after 15 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.8531471212815145 [270] [298,177,112] 6 hSpCas9 negative selection 1637877
45075100 45075123 20 + 26627737 HeLa viability after 15 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -1.0506348793929203 [320] [89,70,24] -7 hSpCas9 negative selection 1637878
44966556 44966579 20 + 26627737 HeLa viability after 18 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.4457322898336917 [788] [67,99,132] -8 hSpCas9 negative selection 1720188
44987207 44987230 20 + 26627737 HeLa viability after 18 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.04614423289827285 [186] [11,117,75] 0 hSpCas9 negative selection 1720189
45000454 45000477 20 + 26627737 HeLa viability after 18 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -2.4241464076892285 [230] [0,22,23] -9 hSpCas9 negative selection 1720190
45001199 45001222 20 + 26627737 HeLa viability after 18 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.4101866367428042 [671] [130,359,470] 3 hSpCas9 negative selection 1720191
45053145 45053168 20 - 26627737 HeLa viability after 18 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.8451976755326768 [270] [201,142,112] 6 hSpCas9 negative selection 1720192
45075100 45075123 20 + 26627737 HeLa viability after 18 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.9752670568292838 [320] [65,59,24] -7 hSpCas9 negative selection 1720193
44966556 44966579 20 + 26627737 HCT116 viability after 6 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.46488072562354593 [601] [123,37] -3 hSpCas9 negative selection 1802503
44987207 44987230 20 + 26627737 HCT116 viability after 6 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.38729741069201895 [348] [88,15] -2 hSpCas9 negative selection 1802504
45000454 45000477 20 + 26627737 HCT116 viability after 6 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.6309044039555072 [308] [80,3] -4 hSpCas9 negative selection 1802505
45001199 45001222 20 + 26627737 HCT116 viability after 6 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.733688516300248 [955] [81,94] -4 hSpCas9 negative selection 1802506
45053145 45053168 20 - 26627737 HCT116 viability after 6 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.5430233364882489 [353] [102,68] 3 hSpCas9 negative selection 1802507
45075100 45075123 20 + 26627737 HCT116 viability after 6 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.5597683414194492 [132] [44,22] 3 hSpCas9 negative selection 1802508
44966556 44966579 20 + 26627737 HCT116 viability after 8 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.7692875718753591 [558] [182,161,196] -7 hSpCas9 negative selection 1884818
44987207 44987230 20 + 26627737 HCT116 viability after 8 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.4449067343691291 [267] [80,137,105] -5 hSpCas9 negative selection 1884819
45000454 45000477 20 + 26627737 HCT116 viability after 8 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.12492677046352474 [152] [89,50,90] -1 hSpCas9 negative selection 1884820
45001199 45001222 20 + 26627737 HCT116 viability after 8 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.2318537967469334 [494] [319,408,232] 2 hSpCas9 negative selection 1884821
45053145 45053168 20 - 26627737 HCT116 viability after 8 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.711515374253332 [500] [259,128,118] -7 hSpCas9 negative selection 1884822
45075100 45075123 20 + 26627737 HCT116 viability after 8 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.7971570590220374 [106] [68,154,82] 7 hSpCas9 negative selection 1884823
44966556 44966579 20 + 26627737 HCT116 viability after 9 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.2528082446621276 [601] [195,187] 2 hSpCas9 negative selection 1967133
44987207 44987230 20 + 26627737 HCT116 viability after 9 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.735958327035569 [348] [157,152] 5 hSpCas9 negative selection 1967134
45000454 45000477 20 + 26627737 HCT116 viability after 9 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.38588482590730744 [308] [18,177] 3 hSpCas9 negative selection 1967135
45001199 45001222 20 + 26627737 HCT116 viability after 9 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.28206478577951866 [955] [262,167] -2 hSpCas9 negative selection 1967136
45053145 45053168 20 - 26627737 HCT116 viability after 9 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.06802138393453849 [353] [140,49] 0 hSpCas9 negative selection 1967137
45075100 45075123 20 + 26627737 HCT116 viability after 9 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 2.3797533654794907 [132] [9,322] 9 hSpCas9 negative selection 1967138
44966556 44966579 20 + 26627737 HCT116 viability after 12 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.0353919970423253 [558] [167,109,148] -8 hSpCas9 negative selection 2049448
44987207 44987230 20 + 26627737 HCT116 viability after 12 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -1.4258074496735462 [267] [34,101,22] -9 hSpCas9 negative selection 2049449
45000454 45000477 20 + 26627737 HCT116 viability after 12 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.3986412708976962 [152] [35,94,54] -4 hSpCas9 negative selection 2049450
45001199 45001222 20 + 26627737 HCT116 viability after 12 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.01812213928936346 [494] [378,175,222] 0 hSpCas9 negative selection 2049451
45053145 45053168 20 - 26627737 HCT116 viability after 12 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.55769291900794 [500] [198,225,110] -6 hSpCas9 negative selection 2049452
45075100 45075123 20 + 26627737 HCT116 viability after 12 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.5447147365592667 [106] [177,13,43] 5 hSpCas9 negative selection 2049453
44966556 44966579 20 + 26627737 HCT116 viability after 15 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -1.2352727448839327 [558] [217,145,55] -8 hSpCas9 negative selection 2131763
44987207 44987230 20 + 26627737 HCT116 viability after 15 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -1.263081411494972 [267] [26,107,52] -8 hSpCas9 negative selection 2131764
45000454 45000477 20 + 26627737 HCT116 viability after 15 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.27149710225716095 [152] [131,54,38] -3 hSpCas9 negative selection 2131765
45001199 45001222 20 + 26627737 HCT116 viability after 15 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.08760719635369907 [494] [309,250,246] -1 hSpCas9 negative selection 2131766
45053145 45053168 20 - 26627737 HCT116 viability after 15 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.3904876810790878 [500] [230,218,209] -4 hSpCas9 negative selection 2131767
45075100 45075123 20 + 26627737 HCT116 viability after 15 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.2863583332618469 [106] [125,26,77] 3 hSpCas9 negative selection 2131768
44966556 44966579 20 + 26627737 HCT116 viability after 18 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.6241739443013352 [558] [191,159,174] -5 hSpCas9 negative selection 2214078
44987207 44987230 20 + 26627737 HCT116 viability after 18 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.35730128430432495 [267] [34,208,49] -3 hSpCas9 negative selection 2214079
45000454 45000477 20 + 26627737 HCT116 viability after 18 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 -0.03668688911248663 [152] [117,38,60] 0 hSpCas9 negative selection 2214080
45001199 45001222 20 + 26627737 HCT116 viability after 18 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 -0.1425149460636287 [494] [246,164,242] -1 hSpCas9 negative selection 2214081
45053145 45053168 20 - 26627737 HCT116 viability after 18 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.5069274721233414 [500] [201,168,138] -4 hSpCas9 negative selection 2214082
45075100 45075123 20 + 26627737 HCT116 viability after 18 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.5687651108889366 [106] [113,62,52] 5 hSpCas9 negative selection 2214083
44966556 44966579 20 + 24336569 HL60 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 2.8707073742804887 [68] [1067] 9 hSpCas9 negative selection 2298011
44966567 44966590 20 + 24336569 HL60 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.6084182728894064 [1303] [1809] -5 hSpCas9 negative selection 2298012
44966582 44966605 20 + 24336569 HL60 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 1.0124224085704339 [434] [1856] 7 hSpCas9 negative selection 2298013
44972110 44972133 20 - 24336569 HL60 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 2.061224316539614 [100] [891] 9 hSpCas9 negative selection 2298014
44972118 44972141 20 - 24336569 HL60 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.20905104162700472 [259] [635] 2 hSpCas9 negative selection 2298015
44972130 44972153 20 + 24336569 HL60 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 0.873588493317129 [325] [1263] 7 hSpCas9 negative selection 2298016
44972136 44972159 20 + 24336569 HL60 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.30408885871451996 [1034] [1773] -3 hSpCas9 negative selection 2298017
44978429 44978452 20 + 24336569 HL60 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 0.808648706750524 [541] [2008] 6 hSpCas9 negative selection 2298018
44978445 44978468 20 - 24336569 HL60 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 3.088142811287072 [251] [4534] 9 hSpCas9 negative selection 2298019
44978462 44978485 20 + 24336569 HL60 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 -0.7985301373573976 [359] [437] -6 hSpCas9 negative selection 2298020
44966556 44966579 20 + 24336569 KBM7 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.19579999039759566 [241] [755] 1 hSpCas9 negative selection 2365188
44966567 44966590 20 + 24336569 KBM7 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 0.9080913238181412 [523] [2681] 7 hSpCas9 negative selection 2365189
44966582 44966605 20 + 24336569 KBM7 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 1.4076955606047188 [367] [2662] 9 hSpCas9 negative selection 2365190
44972110 44972133 20 - 24336569 KBM7 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 1.0233921975873326 [282] [1568] 8 hSpCas9 negative selection 2365191
44972118 44972141 20 - 24336569 KBM7 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.3132781048372913 [409] [899] -3 hSpCas9 negative selection 2365192
44972130 44972153 20 + 24336569 KBM7 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 1.4180174183342373 [214] [1566] 9 hSpCas9 negative selection 2365193
44972136 44972159 20 + 24336569 KBM7 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.05649642942176136 [667] [1751] 0 hSpCas9 negative selection 2365194
44978429 44978452 20 + 24336569 KBM7 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 0.042309712900278296 [783] [2201] 0 hSpCas9 negative selection 2365195
44978445 44978468 20 - 24336569 KBM7 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6553716629172366 [435] [1872] 6 hSpCas9 negative selection 2365196
44978462 44978485 20 + 24336569 KBM7 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.91766006961181 [104] [540] 7 hSpCas9 negative selection 2365197
44968337 44968360 20 - 25494202 A375 resistance to PLX-4720 (puromycin) AGAGACCATCCTGGCTAACACGG STK4 ENSG00000101109 -1.1174807317499718 [30,74] [4,4] -6 dCas9-VP64 positive selection 2405358
45077571 45077594 20 + 25494202 A375 resistance to PLX-4720 (puromycin) GAGACGGGGTTTCACCATGTCAG STK4 ENSG00000101109 1.7100356304154607 [4,2] [3,0] 6 dCas9-VP64 positive selection 2409636
45007502 45007525 20 + 25494202 A375 resistance to PLX-4720 (puromycin) GCGCCACTGCACTCCAGCCCGGG STK4 ENSG00000101109 0.5268875283082193 [1,6] [1,0] 2 dCas9-VP64 positive selection 2458574
44968337 44968360 20 - 25494202 A375 resistance to PLX-4720 (zeocin) AGAGACCATCCTGGCTAACACGG STK4 ENSG00000101109 -0.3866569806865121 [139,148] [35,34] -4 dCas9-VP64 positive selection 2500613
45077571 45077594 20 + 25494202 A375 resistance to PLX-4720 (zeocin) GAGACGGGGTTTCACCATGTCAG STK4 ENSG00000101109 -0.28524240662887035 [88,68] [26,14] -3 dCas9-VP64 positive selection 2504891
45007502 45007525 20 + 25494202 A375 resistance to PLX-4720 (zeocin) GCGCCACTGCACTCCAGCCCGGG STK4 ENSG00000101109 1.3449939631950025 [38,32] [23,34] 7 dCas9-VP64 positive selection 2553829
44995166 44995189 20 + 27260157 DLD1 viability ACAACTGTGTAGCAGACATCTGG STK4 ENSG00000101109 -0.00197574426049228 [] [] 0 hSpCas9 negative selection 2574168
44978509 44978532 20 + 27260157 DLD1 viability TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -0.403230796281159 [] [] -3 hSpCas9 negative selection 2577797
44972130 44972153 20 + 27260157 DLD1 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 0.589661690437177 [] [] 8 hSpCas9 negative selection 2584017
44972136 44972159 20 + 27260157 DLD1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.228976913388618 [] [] 3 hSpCas9 negative selection 2608076
44995249 44995272 20 - 27260157 DLD1 viability GTCCACTTTCTTACCCTCATTGG STK4 ENSG00000101109 0.945636604410998 [] [] 9 hSpCas9 negative selection 2609646
44972110 44972133 20 - 27260157 DLD1 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 -0.044386787377948 [] [] 0 hSpCas9 negative selection 2610012
44978462 44978485 20 + 27260157 DLD1 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.584065323689108 [] [] 8 hSpCas9 negative selection 2610538
44995094 44995117 20 - 27260157 DLD1 viability CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 -0.611057745718454 [] [] -5 hSpCas9 negative selection 2613681
44966556 44966579 20 + 27260157 DLD1 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.134689073629076 [] [] -1 hSpCas9 negative selection 2614024
44995085 44995108 20 + 27260157 DLD1 viability TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.343207736305929 [] [] 4 hSpCas9 negative selection 2620635
44966567 44966590 20 - 27260157 DLD1 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.365183679880472 [] [] -3 hSpCas9 negative selection 2620676
44966567 44966590 20 + 27260157 DLD1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.359585867824165 [] [] -3 hSpCas9 negative selection 2621398
44978429 44978452 20 + 27260157 DLD1 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 0.0695068256947998 [] [] 3 hSpCas9 negative selection 2623578
44966582 44966605 20 + 27260157 DLD1 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 -1.13385961594345 [] [] -7 hSpCas9 negative selection 2642687
44995099 44995122 20 + 27260157 DLD1 viability GCCAAGCGGAATACAGTGATAGG STK4 ENSG00000101109 0.369073632347557 [] [] 4 hSpCas9 negative selection 2643726
44995134 44995157 20 + 27260157 DLD1 viability GATGGCTCCAGAAGTGATTCAGG STK4 ENSG00000101109 0.570974842704008 [] [] 8 hSpCas9 negative selection 2644680
44987207 44987230 20 + 27260157 DLD1 viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.238367703070403 [] [] -2 hSpCas9 negative selection 2644894
44978510 44978533 20 - 27260157 DLD1 viability TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 -0.431979972234184 [] [] -4 hSpCas9 negative selection 2645665
44978445 44978468 20 - 27260157 DLD1 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.0913338008343392 [] [] 3 hSpCas9 negative selection 2647668
44995166 44995189 20 + 27260157 HT1080 viability ACAACTGTGTAGCAGACATCTGG STK4 ENSG00000101109 0.570841433080273 [] [] 5 hSpCas9 negative selection 2650298
44978509 44978532 20 + 27260157 HT1080 viability TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -1.10989632913436 [] [] -8 hSpCas9 negative selection 2653927
44972130 44972153 20 + 27260157 HT1080 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 0.302525539658382 [] [] 3 hSpCas9 negative selection 2660147
44972136 44972159 20 + 27260157 HT1080 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.129079902896152 [] [] 0 hSpCas9 negative selection 2684206
44995249 44995272 20 - 27260157 HT1080 viability GTCCACTTTCTTACCCTCATTGG STK4 ENSG00000101109 0.309713247308502 [] [] 3 hSpCas9 negative selection 2685776
44972110 44972133 20 - 27260157 HT1080 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 0.843440784544042 [] [] 7 hSpCas9 negative selection 2686142
44978462 44978485 20 + 27260157 HT1080 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.286741312106826 [] [] 2 hSpCas9 negative selection 2686668
44995094 44995117 20 - 27260157 HT1080 viability CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 -0.4819002053209 [] [] -7 hSpCas9 negative selection 2689811
44966556 44966579 20 + 27260157 HT1080 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.614934241730966 [] [] 5 hSpCas9 negative selection 2690154
44995085 44995108 20 + 27260157 HT1080 viability TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.194510585527113 [] [] 1 hSpCas9 negative selection 2696765
44966567 44966590 20 - 27260157 HT1080 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.351138673178499 [] [] -7 hSpCas9 negative selection 2696806
44966567 44966590 20 + 27260157 HT1080 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.668170037273148 [] [] -8 hSpCas9 negative selection 2697528
44978429 44978452 20 + 27260157 HT1080 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 -0.286399732263054 [] [] -7 hSpCas9 negative selection 2699708
44966582 44966605 20 + 27260157 HT1080 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 0.523820032946407 [] [] 4 hSpCas9 negative selection 2718817
44995099 44995122 20 + 27260157 HT1080 viability GCCAAGCGGAATACAGTGATAGG STK4 ENSG00000101109 0.80158023760273 [] [] 7 hSpCas9 negative selection 2719856
44995134 44995157 20 + 27260157 HT1080 viability GATGGCTCCAGAAGTGATTCAGG STK4 ENSG00000101109 0.636599353506082 [] [] 5 hSpCas9 negative selection 2720810
44987207 44987230 20 + 27260157 HT1080 viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.346388434166715 [] [] 3 hSpCas9 negative selection 2721024
44978510 44978533 20 - 27260157 HT1080 viability TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 0.0551274030663064 [] [] 0 hSpCas9 negative selection 2721795
44978445 44978468 20 - 27260157 HT1080 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.176384573006778 [] [] 1 hSpCas9 negative selection 2723798
44995166 44995189 20 + 27260157 MKN45 viability ACAACTGTGTAGCAGACATCTGG STK4 ENSG00000101109 0.212325979187696 [] [] 5 hSpCas9 negative selection 2726428
44978509 44978532 20 + 27260157 MKN45 viability TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -0.299795250272503 [] [] -1 hSpCas9 negative selection 2730057
44972130 44972153 20 + 27260157 MKN45 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 0.793609899773887 [] [] 7 hSpCas9 negative selection 2736277
44972136 44972159 20 + 27260157 MKN45 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.086927335249619 [] [] 0 hSpCas9 negative selection 2760336
44995249 44995272 20 - 27260157 MKN45 viability GTCCACTTTCTTACCCTCATTGG STK4 ENSG00000101109 -0.0801093970036361 [] [] 0 hSpCas9 negative selection 2761906
44972110 44972133 20 - 27260157 MKN45 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 0.788463108460686 [] [] 7 hSpCas9 negative selection 2762272
44978462 44978485 20 + 27260157 MKN45 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 -1.36644597810921 [] [] -8 hSpCas9 negative selection 2762798
44995094 44995117 20 - 27260157 MKN45 viability CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 -0.190620078208532 [] [] 0 hSpCas9 negative selection 2765941
44966556 44966579 20 + 27260157 MKN45 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.0547841530999187 [] [] 0 hSpCas9 negative selection 2766284
44995085 44995108 20 + 27260157 MKN45 viability TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.151550142419911 [] [] 5 hSpCas9 negative selection 2772895
44966567 44966590 20 - 27260157 MKN45 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.348013667181702 [] [] -1 hSpCas9 negative selection 2772936
44966567 44966590 20 + 27260157 MKN45 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.554658695404697 [] [] -6 hSpCas9 negative selection 2773658
44978429 44978452 20 + 27260157 MKN45 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 -0.467647939660912 [] [] -6 hSpCas9 negative selection 2775838
44966582 44966605 20 + 27260157 MKN45 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 0.581224574547964 [] [] 7 hSpCas9 negative selection 2794947
44995099 44995122 20 + 27260157 MKN45 viability GCCAAGCGGAATACAGTGATAGG STK4 ENSG00000101109 0.751492060770863 [] [] 7 hSpCas9 negative selection 2795986
44995134 44995157 20 + 27260157 MKN45 viability GATGGCTCCAGAAGTGATTCAGG STK4 ENSG00000101109 0.506678909979171 [] [] 6 hSpCas9 negative selection 2796940
44987207 44987230 20 + 27260157 MKN45 viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.206000459873187 [] [] 5 hSpCas9 negative selection 2797154
44978510 44978533 20 - 27260157 MKN45 viability TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 -0.562342150200304 [] [] -6 hSpCas9 negative selection 2797925
44978445 44978468 20 - 27260157 MKN45 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.172174080503168 [] [] 0 hSpCas9 negative selection 2799928
44995166 44995189 20 + 27260157 RKO viability ACAACTGTGTAGCAGACATCTGG STK4 ENSG00000101109 -0.0811317851400049 [] [] 0 hSpCas9 negative selection 2802558
44978509 44978532 20 + 27260157 RKO viability TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -0.096333736653648 [] [] 0 hSpCas9 negative selection 2806187
44972130 44972153 20 + 27260157 RKO viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 0.353544563125964 [] [] 2 hSpCas9 negative selection 2812407
44972136 44972159 20 + 27260157 RKO viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.465332215561713 [] [] -6 hSpCas9 negative selection 2836466
44995249 44995272 20 - 27260157 RKO viability GTCCACTTTCTTACCCTCATTGG STK4 ENSG00000101109 -0.788193208872825 [] [] -7 hSpCas9 negative selection 2838036
44972110 44972133 20 - 27260157 RKO viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 0.459849112071076 [] [] 2 hSpCas9 negative selection 2838402
44978462 44978485 20 + 27260157 RKO viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.169783039543903 [] [] 0 hSpCas9 negative selection 2838928
44995094 44995117 20 - 27260157 RKO viability CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 0.0498580519241926 [] [] 0 hSpCas9 negative selection 2842071
44966556 44966579 20 + 27260157 RKO viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.221929316927554 [] [] -1 hSpCas9 negative selection 2842414
44995085 44995108 20 + 27260157 RKO viability TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.0245018402887645 [] [] 0 hSpCas9 negative selection 2849025
44966567 44966590 20 - 27260157 RKO viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.14769350167024 [] [] 0 hSpCas9 negative selection 2849066
44966567 44966590 20 + 27260157 RKO viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -1.28939323110713 [] [] -8 hSpCas9 negative selection 2849788
44978429 44978452 20 + 27260157 RKO viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 -0.640469783445886 [] [] -7 hSpCas9 negative selection 2851968
44966582 44966605 20 + 27260157 RKO viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 -0.440389968840584 [] [] -6 hSpCas9 negative selection 2871077
44995099 44995122 20 + 27260157 RKO viability GCCAAGCGGAATACAGTGATAGG STK4 ENSG00000101109 1.31969184999002 [] [] 9 hSpCas9 negative selection 2872116
44995134 44995157 20 + 27260157 RKO viability GATGGCTCCAGAAGTGATTCAGG STK4 ENSG00000101109 0.152173534423628 [] [] 0 hSpCas9 negative selection 2873070
44987207 44987230 20 + 27260157 RKO viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.0288221269334457 [] [] 0 hSpCas9 negative selection 2873284
44978510 44978533 20 - 27260157 RKO viability TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 -0.46501251635946 [] [] -6 hSpCas9 negative selection 2874055
44978445 44978468 20 - 27260157 RKO viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.108665274963043 [] [] 0 hSpCas9 negative selection 2876058
44995166 44995189 20 + 27260157 SF268 viability ACAACTGTGTAGCAGACATCTGG STK4 ENSG00000101109 0.110170825309671 [] [] 0 hSpCas9 negative selection 2878688
44978509 44978532 20 + 27260157 SF268 viability TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -0.0854675290708431 [] [] 0 hSpCas9 negative selection 2882317
44972130 44972153 20 + 27260157 SF268 viability TTTGATGTCTTAGAGAAACTTGG STK4 ENSG00000101109 -0.0758745230039227 [] [] 0 hSpCas9 negative selection 2888537
44972136 44972159 20 + 27260157 SF268 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -1.40506726783223 [] [] -8 hSpCas9 negative selection 2912596
44995249 44995272 20 - 27260157 SF268 viability GTCCACTTTCTTACCCTCATTGG STK4 ENSG00000101109 -0.0521142759853747 [] [] 0 hSpCas9 negative selection 2914166
44972110 44972133 20 - 27260157 SF268 viability AAATACTTCTTCTGGTTGTTTGG STK4 ENSG00000101109 0.742651840377574 [] [] 8 hSpCas9 negative selection 2914532
44978462 44978485 20 + 27260157 SF268 viability AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.359335465819647 [] [] 4 hSpCas9 negative selection 2915058
44995094 44995117 20 - 27260157 SF268 viability CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 -0.141181452586239 [] [] -1 hSpCas9 negative selection 2918201
44966556 44966579 20 + 27260157 SF268 viability TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.732933731883609 [] [] 8 hSpCas9 negative selection 2918544
44995085 44995108 20 + 27260157 SF268 viability TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.238073032452718 [] [] 3 hSpCas9 negative selection 2925155
44966567 44966590 20 - 27260157 SF268 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.553428817833222 [] [] -4 hSpCas9 negative selection 2925196
44966567 44966590 20 + 27260157 SF268 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.0428449320271247 [] [] 0 hSpCas9 negative selection 2925918
44978429 44978452 20 + 27260157 SF268 viability TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 0.217945544727831 [] [] 3 hSpCas9 negative selection 2928098
44966582 44966605 20 + 27260157 SF268 viability AGCTGAGGAACCCGCCGCGCCGG STK4 ENSG00000101109 -0.0168819333752667 [] [] 0 hSpCas9 negative selection 2947207
44995099 44995122 20 + 27260157 SF268 viability GCCAAGCGGAATACAGTGATAGG STK4 ENSG00000101109 0.908806249916672 [] [] 9 hSpCas9 negative selection 2948246
44995134 44995157 20 + 27260157 SF268 viability GATGGCTCCAGAAGTGATTCAGG STK4 ENSG00000101109 0.672643496022236 [] [] 8 hSpCas9 negative selection 2949200
44987207 44987230 20 + 27260157 SF268 viability ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.205870101948923 [] [] 3 hSpCas9 negative selection 2949414
44978510 44978533 20 - 27260157 SF268 viability TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 -0.0543809364863535 [] [] 0 hSpCas9 negative selection 2950185
44978445 44978468 20 - 27260157 SF268 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.224934857018263 [] [] 3 hSpCas9 negative selection 2952188
44978421 44978444 20 + 27013184 SW480 treatment with recombinant TRAIL TCTTCTTCTCCCAAATGTATAGG STK4 ENSG00000101109 1.0337011139415786 [175,307] [220,190] 5 hSpCas9 positive selection 2956221
44978429 44978452 20 + 27013184 SW480 treatment with recombinant TRAIL TCCCAAATGTATAGGTCCTATGG STK4 ENSG00000101109 1.18301722733147 [300,229] [138,439] 5 hSpCas9 positive selection 2956222
44981868 44981891 20 + 27013184 SW480 treatment with recombinant TRAIL CACAGACTTATGGATCGTTATGG STK4 ENSG00000101109 -1.7281759675374646 [18,10] [1,1] -7 hSpCas9 positive selection 2956223
44981922 44981945 20 + 27013184 SW480 treatment with recombinant TRAIL CATTCGATTACGAAATAAAACGG STK4 ENSG00000101109 -1.3042581636474582 [52,23] [1,13] -6 hSpCas9 positive selection 2956224
44981926 44981949 20 + 27013184 SW480 treatment with recombinant TRAIL CGATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 1.105507087014384 [46,165] [126,46] 5 hSpCas9 positive selection 2956225
44978462 44978485 20 + 27013184 SW480 treatment with recombinant TRAIL AAAGCTATTCATAAAGAGACCGG STK4 ENSG00000101109 0.677777165977693 [59,77] [63,22] 3 hSpCas9 positive selection 2956226
44972056 44972079 20 + 27013184 SW480 treatment with recombinant TRAIL GTTTATATTTCTTTATTCACAGG STK4 ENSG00000101109 -0.43100365388290207 [61,17] [5,23] -2 hSpCas9 positive selection 2956227
44972072 44972095 20 + 27013184 SW480 treatment with recombinant TRAIL TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 1.4335314626856028 [133,199] [111,303] 6 hSpCas9 positive selection 2956228
44966567 44966590 20 + 27013184 SW480 treatment with recombinant TRAIL CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -4.187128550738964 [57,115] [1,1] -9 hSpCas9 positive selection 2956229
44978430 44978453 20 - 27013184 SW480 treatment with recombinant TRAIL GCCATAGGACCTATACATTTGGG STK4 ENSG00000101109 -0.2811373323438747 [398,239] [51,206] -1 hSpCas9 positive selection 2956230
44978431 44978454 20 - 27013184 SW480 treatment with recombinant TRAIL TGCCATAGGACCTATACATTTGG STK4 ENSG00000101109 1.822007586438275 [48,19] [21,100] 7 hSpCas9 positive selection 2956231
44978445 44978468 20 - 27013184 SW480 treatment with recombinant TRAIL AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.2747359998326777 [798,889] [234,391] -1 hSpCas9 positive selection 2956232
44978481 44978504 20 - 27013184 SW480 treatment with recombinant TRAIL CTTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.4325764378662839 [120,126] [43,111] 2 hSpCas9 positive selection 2956233
44978485 44978508 20 - 27013184 SW480 treatment with recombinant TRAIL CTTGCTTAATAGCAACAATCTGG STK4 ENSG00000101109 0.9910996332623379 [12,37] [3,44] 5 hSpCas9 positive selection 2956234
44978510 44978533 20 - 27013184 SW480 treatment with recombinant TRAIL TCCTGGAGGTCTGATTCCACAGG STK4 ENSG00000101109 1.2037274256086372 [65,103] [114,36] 5 hSpCas9 positive selection 2956235
44978494 44978517 20 + 27013184 SW480 treatment with recombinant TRAIL TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.14200153831627138 [161,124] [57,54] 0 hSpCas9 positive selection 2956236
44978524 44978547 20 - 27013184 SW480 treatment with recombinant TRAIL TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 -0.6669555460358377 [89,200] [24,56] -3 hSpCas9 positive selection 2956237
44978527 44978550 20 - 27013184 SW480 treatment with recombinant TRAIL AGATTTCTTTGATTATCTCCTGG STK4 ENSG00000101109 -0.5024467943484741 [39,22] [8,10] -2 hSpCas9 positive selection 2956238
44981829 44981852 20 - 27013184 SW480 treatment with recombinant TRAIL CATAATATTTGACTACATGAGGG STK4 ENSG00000101109 -1.5372473444875259 [67,56] [3,16] -6 hSpCas9 positive selection 2956239
44981830 44981853 20 - 27013184 SW480 treatment with recombinant TRAIL CCATAATATTTGACTACATGAGG STK4 ENSG00000101109 3.009039547378899 [6,6] [13,38] 9 hSpCas9 positive selection 2956240
44972118 44972141 20 - 27013184 SW480 treatment with recombinant TRAIL AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.6751590054087424 [777,736] [217,186] -3 hSpCas9 positive selection 2956241
44978509 44978532 20 + 27013184 SW480 treatment with recombinant TRAIL TCCTGTGGAATCAGACCTCCAGG STK4 ENSG00000101109 -0.5417513179407357 [395,349] [85,146] -2 hSpCas9 positive selection 2956242
44995094 44995117 20 - 27013184 SW480 treatment with recombinant TRAIL CACTGTATTCCGCTTGGCCATGG STK4 ENSG00000101109 0.06520377136825564 [207,260] [58,169] 0 hSpCas9 positive selection 2956243
44995100 44995123 20 - 27013184 SW480 treatment with recombinant TRAIL TCCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 1.8425498927682409 [293,519] [712,473] 7 hSpCas9 positive selection 2956244
44978550 44978573 20 + 27013184 SW480 treatment with recombinant TRAIL CTATAATGCAGCAATGTGACAGG STK4 ENSG00000101109 -0.2165215125119333 [79,49] [3,53] -1 hSpCas9 positive selection 2956245
44978556 44978579 20 + 27013184 SW480 treatment with recombinant TRAIL TGCAGCAATGTGACAGGTAAAGG STK4 ENSG00000101109 1.318329573585982 [175,302] [294,189] 6 hSpCas9 positive selection 2956246
44966604 44966627 20 + 27013184 SW480 treatment with recombinant TRAIL GTGAGGGGCCACTGGCTAAGAGG STK4 ENSG00000101109 1.8063765909242853 [23,63] [26,115] 7 hSpCas9 positive selection 2956247
44981830 44981853 20 + 27013184 SW480 treatment with recombinant TRAIL CCTCATGTAGTCAAATATTATGG STK4 ENSG00000101109 5.1127910562539345 [1,2] [1,85] 9 hSpCas9 positive selection 2956248
44995112 44995135 20 + 27013184 SW480 treatment with recombinant TRAIL CAGTGATAGGAACACCATTTTGG STK4 ENSG00000101109 0.8768127950171991 [387,273] [314,196] 4 hSpCas9 positive selection 2956249
44981858 44981881 20 + 27013184 SW480 treatment with recombinant TRAIL ATTTTAAGAACACAGACTTATGG STK4 ENSG00000101109 -1.9113699960326598 [87,169] [1,31] -7 hSpCas9 positive selection 2956250
44978550 44978573 20 - 27013184 SW480 treatment with recombinant TRAIL CCTGTCACATTGCTGCATTATAG STK4 ENSG00000101109 -0.003973180806580212 [194,402] [101,156] 0 hSpCas9 positive selection 2956866
44981881 44981904 20 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 0.0621388524171122 [5,5] [4,4] 1 hSpCas9 positive selection 3024335
44995228 44995251 20 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 0.0734489040381365 [3,3] [3,2] 1 hSpCas9 positive selection 3024336
44995086 44995109 20 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.7089082476683354 [3,3] [5,5] 9 hSpCas9 positive selection 3024337
44978524 44978547 20 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 0.27875886540553974 [6,6] [6,6] 6 hSpCas9 positive selection 3024338
44981881 44981904 20 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 0.22821946685344147 [5,5] [4,3] 4 hSpCas9 positive selection 3092193
44995228 44995251 20 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 -0.4552707388815514 [3,3] [3,0] -6 hSpCas9 positive selection 3092194
44995086 44995109 20 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 -0.06404879368092052 [3,3] [3,1] -1 hSpCas9 positive selection 3092195
44978524 44978547 20 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 0.447777007455081 [6,6] [6,5] 7 hSpCas9 positive selection 3092196
44972118 44972141 - 24336571 A375 resistance to PLX after 7 days AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.0012352697409192537 [1,1] [1,1] 0 hSpCas9 positive selection 3148048
44966567 44966590 - 24336571 A375 resistance to PLX after 7 days CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.09531794246397496 [29,29] [33,28] 3 hSpCas9 positive selection 3148049
44966593 44966616 - 24336571 A375 resistance to PLX after 7 days GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 -0.12740398678911924 [5,6] [5,5] -4 hSpCas9 positive selection 3148050
44972118 44972141 - 24336571 A375 resistance to PLX after 14 days AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.7705017847218933 [1,1] [1,1] 6 hSpCas9 positive selection 3205841
44966567 44966590 - 24336571 A375 resistance to PLX after 14 days CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.33244615780239695 [27,27] [15,16] 3 hSpCas9 positive selection 3205842
44966593 44966616 - 24336571 A375 resistance to PLX after 14 days GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 -0.448077687776534 [5,9] [1,2] -5 hSpCas9 positive selection 3205843
44972118 44972141 - 24336571 A375 viability after 7 days AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.2918591186090942 [1] [1,1] 4 hSpCas9 negative selection 3263634
44966567 44966590 - 24336571 A375 viability after 7 days CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.2943411111969505 [25] [29,29] 4 hSpCas9 negative selection 3263635
44966593 44966616 - 24336571 A375 viability after 7 days GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 -0.1310873812630705 [7] [5,6] -2 hSpCas9 negative selection 3263636
44972118 44972141 - 24336571 A375 viability after 14 days AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.3095164836888773 [1] [1,1] 4 hSpCas9 negative selection 3321427
44966567 44966590 - 24336571 A375 viability after 14 days CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.22587880454479836 [25] [27,27] 3 hSpCas9 negative selection 3321428
44966593 44966616 - 24336571 A375 viability after 14 days GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 0.16564401445016885 [7] [5,9] 2 hSpCas9 negative selection 3321429
44978494 44978517 20 + 27383988 293T resistance to West Nile virus (flavivirus) TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -1.7788474011076498 [524,524] [0,0] -9 hSpCas9 positive selection 3395420
44972072 44972095 20 + 27383988 293T resistance to West Nile virus (flavivirus) TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 1.0093986980022496 [75,75] [0,0] 4 hSpCas9 positive selection 3395421
44972118 44972141 20 - 27383988 293T resistance to West Nile virus (flavivirus) AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 1.399345216318263 [57,57] [0,0] 6 hSpCas9 positive selection 3395422
44981880 44981903 20 + 26780180 HT29 viability (Avana library 4 designs) GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 -0.0323973733963674 [] [] 0 hSpCas9 negative selection 3463020
44995228 44995251 20 - 26780180 HT29 viability (Avana library 4 designs) GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 1.15181918821049 [] [] 4 hSpCas9 negative selection 3463021
44995085 44995108 20 + 26780180 HT29 viability (Avana library 4 designs) TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 1.6642042388723 [] [] 6 hSpCas9 negative selection 3463022
44978524 44978547 20 - 26780180 HT29 viability (Avana library 4 designs) TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 -0.81325631316399 [] [] -9 hSpCas9 negative selection 3463023
44995228 44995251 20 - 26780180 A375 viability (Avana lentiCRISPRv2) GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 0.0354495158756188 [] [] 0 hSpCas9 negative selection 3564866
44995085 44995108 20 + 26780180 A375 viability (Avana lentiCRISPRv2) TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.575436743748208 [] [] 0 hSpCas9 negative selection 3564867
44978524 44978547 20 - 26780180 A375 viability (Avana lentiCRISPRv2) TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 -2.37941599587355 [] [] -3 hSpCas9 negative selection 3564868
44981880 44981903 20 + 26780180 A375 viability (Avana lentiCRISPRv2) GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 0.763759809081267 [] [] 1 hSpCas9 negative selection 3564869
44978481 44978504 20 - 26780180 A375 viability (Avana lentiCRISPRv2) CTTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -2.66716101694195 [] [] -3 hSpCas9 negative selection 3564870
44995245 44995268 20 - 26780180 A375 viability (Avana lentiCRISPRv2) ACTTTCTTACCCTCATTGGATGG STK4 ENSG00000101109 -3.77455757518915 [] [] -4 hSpCas9 negative selection 3564871
44995228 44995251 20 - 26780180 A375 viability (Avana lentiGuide) GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 -0.736008734171761 [] [] -1 hSpCas9 negative selection 3673525
44995085 44995108 20 + 26780180 A375 viability (Avana lentiGuide) TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 -2.79729750336448 [] [] -5 hSpCas9 negative selection 3673526
44978524 44978547 20 - 26780180 A375 viability (Avana lentiGuide) TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 -0.875839422559618 [] [] -1 hSpCas9 negative selection 3673527
44981880 44981903 20 + 26780180 A375 viability (Avana lentiGuide) GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 1.98267974673153 [] [] 2 hSpCas9 negative selection 3673528
44978481 44978504 20 - 26780180 A375 viability (Avana lentiGuide) CTTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.424217279712903 [] [] 0 hSpCas9 negative selection 3673529
44995245 44995268 20 - 26780180 A375 viability (Avana lentiGuide) ACTTTCTTACCCTCATTGGATGG STK4 ENSG00000101109 2.34529687105841 [] [] 2 hSpCas9 negative selection 3673530
44995228 44995251 20 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 -0.12062063760337256 [5] [6,2] -2 hSpCas9 positive selection 3782132
44995085 44995108 20 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 0.06038858449596823 [5] [5,4] 1 hSpCas9 positive selection 3782133
44978524 44978547 20 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 -0.1182717417134892 [8] [7,7] -2 hSpCas9 positive selection 3782134
44981880 44981903 20 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 0.09401457412026515 [6] [6,6] 2 hSpCas9 positive selection 3782135
44978481 44978504 20 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.1143875910132651 [5] [5,4] -2 hSpCas9 positive selection 3782136
44995245 44995268 20 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACTTTCTTACCCTCATTGGATGG STK4 ENSG00000101109 -0.3841264599743679 [5] [4,3] -5 hSpCas9 positive selection 3782137
44995228 44995251 20 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GGATGGATATCAGCATAAGGGGG STK4 ENSG00000101109 -0.030289749154276388 [5] [3,4] 0 hSpCas9 positive selection 3890739
44995085 44995108 20 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTTAGGATACCATGGCCAAGCGG STK4 ENSG00000101109 -0.04931722757403594 [5] [3,4] 0 hSpCas9 positive selection 3890740
44978524 44978547 20 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTTCTTTGATTATCTCCTGGAGG STK4 ENSG00000101109 0.24535558884658348 [7] [8,7] 6 hSpCas9 positive selection 3890741
44981880 44981903 20 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GATCGTTATGGAGTACTGTGGGG STK4 ENSG00000101109 0.2110096874368026 [6] [6,6] 5 hSpCas9 positive selection 3890742
44978481 44978504 20 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.033489266670098015 [5] [3,6] 0 hSpCas9 positive selection 3890743
44995245 44995268 20 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACTTTCTTACCCTCATTGGATGG STK4 ENSG00000101109 0.15259015671318815 [5] [4,4] 3 hSpCas9 positive selection 3890744
44972118 44972141 20 - 26780180 A375 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 1.35550039533829 [] [] 7 hSpCas9 negative selection 4000419
44978445 44978468 20 - 26780180 A375 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.11713694295848 [] [] 5 hSpCas9 negative selection 4000420
44966567 44966590 20 - 26780180 A375 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.51889403913515 [] [] 1 hSpCas9 negative selection 4000421
44972072 44972095 20 + 26780180 A375 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.679878416662533 [] [] 2 hSpCas9 negative selection 4000422
44978494 44978517 20 + 26780180 A375 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.303559923830432 [] [] 0 hSpCas9 negative selection 4000423
44966592 44966615 20 - 26780180 A375 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 1.28994300257613 [] [] 7 hSpCas9 negative selection 4000424
44972118 44972141 20 - 26780180 HT29 viability (GeCKOv2 library) AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 1.75693331300334 [] [] 8 hSpCas9 negative selection 4108385
44978445 44978468 20 - 26780180 HT29 viability (GeCKOv2 library) AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.34322870457609 [] [] 6 hSpCas9 negative selection 4108386
44966567 44966590 20 - 26780180 HT29 viability (GeCKOv2 library) CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.398532164378754 [] [] 1 hSpCas9 negative selection 4108387
44972072 44972095 20 + 26780180 HT29 viability (GeCKOv2 library) TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 1.135313296596 [] [] 5 hSpCas9 negative selection 4108388
44978494 44978517 20 + 26780180 HT29 viability (GeCKOv2 library) TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.206401898769597 [] [] 0 hSpCas9 negative selection 4108389
44966592 44966615 20 - 26780180 HT29 viability (GeCKOv2 library) TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 1.4533161550762 [] [] 7 hSpCas9 negative selection 4108390
44972118 44972141 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.4230171014023877 [2] [1,0] -8 hSpCas9 positive selection 4174281
44966567 44966590 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.026374549710435458 [5] [2,3] 0 hSpCas9 positive selection 4174282
44966593 44966616 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 -0.7039886372388275 [3] [1,0] -9 hSpCas9 positive selection 4174283
44972118 44972141 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.08368079678501146 [3] [1,2,2,0] 0 hSpCas9 positive selection 4238303
44966567 44966590 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 1.3405851203337296 [3] [4,3,2,5] 9 hSpCas9 positive selection 4238304
44966593 44966616 20 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GTGGCCCCTCACCGGCGCGGCGG STK4 ENSG00000101109 1.4777499251060475 [2] [0,3,2,4] 9 hSpCas9 positive selection 4238305
44978445 44978468 20 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.07184742055858817 [2] [2,1] 1 hSpCas9 positive selection 4301134
44966592 44966615 20 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.375165447238868 [2] [1,0] -7 hSpCas9 positive selection 4301135
44966567 44966590 20 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.1364523872745666 [3] [3,2] 2 hSpCas9 positive selection 4301136
44978494 44978517 20 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.3277475606676493 [3] [3,3] 6 hSpCas9 positive selection 4365389
44972072 44972095 20 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.44551661099524464 [1] [1,1] 8 hSpCas9 positive selection 4365390
44972118 44972141 20 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.18760983540196824 [2] [2,0] -4 hSpCas9 positive selection 4365391
44978445 44978467 20 - 27760321 OCIAML3 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.350988725323449 [676,661] [371,462] -4 hSpCas9 negative selection 4443961
44978481 44978503 20 - 27760321 OCIAML3 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.38868375095660157 [311,241] [106,238] -4 hSpCas9 negative selection 4443962
44981927 44981949 20 + 27760321 OCIAML3 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -4.411137185271571 [42,41] [1,0] -9 hSpCas9 negative selection 4443963
44995100 44995122 20 - 27760321 OCIAML3 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.11771955449867855 [765,656] [459,786] 1 hSpCas9 negative selection 4443964
44997200 44997222 20 - 27760321 OCIAML3 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.4040757116579592 [568,540] [502,668] 5 hSpCas9 negative selection 4443965
44978445 44978467 20 - 27760321 OCIAML2 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.2670238530399974 [676,661] [531,812] 3 hSpCas9 negative selection 4527424
44978481 44978503 20 - 27760321 OCIAML2 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.7870014742020174 [311,241] [115,145] -7 hSpCas9 negative selection 4527425
44981927 44981949 20 + 27760321 OCIAML2 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 0.025822693068512148 [42,41] [22,50] 0 hSpCas9 negative selection 4527426
44995100 44995122 20 - 27760321 OCIAML2 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 -0.20112554086452977 [765,656] [452,559] -3 hSpCas9 negative selection 4527427
44997200 44997222 20 - 27760321 OCIAML2 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.36899083201118865 [568,540] [523,654] 5 hSpCas9 negative selection 4527428
44978445 44978467 20 - 27760321 MV411 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.04475345423423771 [676,661] [334,570] 0 hSpCas9 negative selection 4610887
44978481 44978503 20 - 27760321 MV411 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 1.0680801386862773 [311,241] [541,137] 7 hSpCas9 negative selection 4610888
44981927 44981949 20 + 27760321 MV411 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -1.1812094037463958 [42,41] [7,18] -6 hSpCas9 negative selection 4610889
44995100 44995122 20 - 27760321 MV411 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.07392206630026721 [765,656] [636,275] 0 hSpCas9 negative selection 4610890
44997200 44997222 20 - 27760321 MV411 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.2536767514758226 [568,540] [174,830] 1 hSpCas9 negative selection 4610891
44978445 44978467 20 - 27760321 HL60 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.18739148116400617 [676,661] [428,536] -2 hSpCas9 negative selection 4694350
44978481 44978503 20 - 27760321 HL60 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.03989204375099398 [311,241] [219,216] 0 hSpCas9 negative selection 4694351
44981927 44981949 20 + 27760321 HL60 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -2.4500374020904805 [42,41] [1,10] -9 hSpCas9 negative selection 4694352
44995100 44995122 20 - 27760321 HL60 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.17597755307991125 [765,656] [741,561] 2 hSpCas9 negative selection 4694353
44997200 44997222 20 - 27760321 HL60 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.5886788185081607 [568,540] [454,923] 7 hSpCas9 negative selection 4694354
44978445 44978467 20 - 27760321 HT1080 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.1347909546994666 [661,516] [561,464] 6 hSpCas9 negative selection 4777813
44978481 44978503 20 - 27760321 HT1080 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.29866908512653406 [241,188] [54,160] 1 hSpCas9 negative selection 4777814
44981927 44981949 20 + 27760321 HT1080 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 0.4445039217458828 [41,32] [37,0] 2 hSpCas9 negative selection 4777815
44995100 44995122 20 - 27760321 HT1080 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 2.208850426879108 [656,512] [1001,1159] 9 hSpCas9 negative selection 4777816
44997200 44997222 20 - 27760321 HT1080 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.9954546622970574 [540,421] [232,545] 5 hSpCas9 negative selection 4777817
44978445 44978467 20 - 27760321 HT29 viability after 7 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.12871419083992952 [661,516] [855,620,1005] 2 hSpCas9 negative selection 4861276
44978481 44978503 20 - 27760321 HT29 viability after 7 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.5365746823807215 [241,188] [240,86,249] -7 hSpCas9 negative selection 4861277
44981927 44981949 20 + 27760321 HT29 viability after 7 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -1.1097022045807914 [41,32] [53,9,7] -8 hSpCas9 negative selection 4861278
44995100 44995122 20 - 27760321 HT29 viability after 7 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.08744021669214952 [656,512] [890,705,811] 1 hSpCas9 negative selection 4861279
44997200 44997222 20 - 27760321 HT29 viability after 7 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.06914168943010857 [540,421] [902,445,634] 1 hSpCas9 negative selection 4861280
44978445 44978467 20 - 27760321 HT29 viability after 25 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.49474629501809897 [661,516] [1074,922,827] 5 hSpCas9 negative selection 4944739
44978481 44978503 20 - 27760321 HT29 viability after 25 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.014923902048852633 [241,188] [111,229,414] 0 hSpCas9 negative selection 4944740
44981927 44981949 20 + 27760321 HT29 viability after 25 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 0.12467714991826195 [41,32] [59,43,33] 1 hSpCas9 negative selection 4944741
44995100 44995122 20 - 27760321 HT29 viability after 25 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.6960413449980434 [656,512] [1077,1026,1149] 7 hSpCas9 negative selection 4944742
44997200 44997222 20 - 27760321 HT29 viability after 25 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.17009125943602343 [540,421] [475,652,749] 1 hSpCas9 negative selection 4944743
44978445 44978467 20 - 27760321 HT29 viability after 22 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6263499010092828 [661,516] [989,981,1186] 7 hSpCas9 negative selection 5028202
44978481 44978503 20 - 27760321 HT29 viability after 22 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.04950914622665348 [241,188] [180,281,260] 0 hSpCas9 negative selection 5028203
44981927 44981949 20 + 27760321 HT29 viability after 22 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 0.9315104926420084 [41,32] [86,81,78] 9 hSpCas9 negative selection 5028204
44995100 44995122 20 - 27760321 HT29 viability after 22 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.6362254787151205 [656,512] [1198,1048,899] 7 hSpCas9 negative selection 5028205
44997200 44997222 20 - 27760321 HT29 viability after 22 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.062303123767312174 [540,421] [527,631,584] 0 hSpCas9 negative selection 5028206
44978445 44978467 20 - 27760321 HT29 viability after 19 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.1418425003798114 [661,516] [786,740,708] 1 hSpCas9 negative selection 5111665
44978481 44978503 20 - 27760321 HT29 viability after 19 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.08181104233954095 [241,188] [406,325,71] 0 hSpCas9 negative selection 5111666
44981927 44981949 20 + 27760321 HT29 viability after 19 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -1.3261304141086607 [41,32] [10,30,8] -7 hSpCas9 negative selection 5111667
44995100 44995122 20 - 27760321 HT29 viability after 19 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.5005346108298871 [656,512] [1380,730,778] 5 hSpCas9 negative selection 5111668
44997200 44997222 20 - 27760321 HT29 viability after 19 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.11602449977620144 [540,421] [479,842,459] 1 hSpCas9 negative selection 5111669
44978445 44978467 20 - 27760321 HT29 viability after 16 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.1555743611342112 [661,516] [552,914,713] 1 hSpCas9 negative selection 5195128
44978481 44978503 20 - 27760321 HT29 viability after 16 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.3247065123421632 [241,188] [291,112,183] -3 hSpCas9 negative selection 5195129
44981927 44981949 20 + 27760321 HT29 viability after 16 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 0.6366258540318857 [41,32] [17,37,135] 7 hSpCas9 negative selection 5195130
44995100 44995122 20 - 27760321 HT29 viability after 16 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.4914821728383949 [656,512] [985,981,796] 5 hSpCas9 negative selection 5195131
44997200 44997222 20 - 27760321 HT29 viability after 16 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.17340820463537543 [540,421] [598,628,592] 1 hSpCas9 negative selection 5195132
44978445 44978467 20 - 27760321 HT29 viability after 13 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.004184631827943486 [661,516] [514,728,794] 0 hSpCas9 negative selection 5278591
44978481 44978503 20 - 27760321 HT29 viability after 13 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.09479347346902645 [241,188] [176,300,224] -1 hSpCas9 negative selection 5278592
44981927 44981949 20 + 27760321 HT29 viability after 13 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -0.009692004452339642 [41,32] [22,33,70] 0 hSpCas9 negative selection 5278593
44995100 44995122 20 - 27760321 HT29 viability after 13 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.16089681055096017 [656,512] [1062,514,700] 2 hSpCas9 negative selection 5278594
44997200 44997222 20 - 27760321 HT29 viability after 13 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 0.2031327372685655 [540,421] [477,597,840] 2 hSpCas9 negative selection 5278595
44978445 44978467 20 - 27760321 HT29 viability after 10 days GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 -0.04914648032397606 [661,516] [956,679,500] 0 hSpCas9 negative selection 5362054
44978481 44978503 20 - 27760321 HT29 viability after 10 days TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 0.15233279887951456 [241,188] [409,267,219] 2 hSpCas9 negative selection 5362055
44981927 44981949 20 + 27760321 HT29 viability after 10 days GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -0.5414704556349097 [41,32] [14,28,51] -6 hSpCas9 negative selection 5362056
44995100 44995122 20 - 27760321 HT29 viability after 10 days CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.29063463660179434 [656,512] [1121,927,636] 4 hSpCas9 negative selection 5362057
44997200 44997222 20 - 27760321 HT29 viability after 10 days AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 -0.047460175592592524 [540,421] [606,549,586] 0 hSpCas9 negative selection 5362058
44978445 44978467 20 - 27760321 MOLM13 viability GCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.12243687031108808 [676,661] [288,516] 0 hSpCas9 negative selection 5445517
44978481 44978503 20 - 27760321 MOLM13 viability TTAATAGCAACAATCTGGCCGG STK4 ENSG00000101109 -0.548321766275473 [311,241] [70,135] -4 hSpCas9 negative selection 5445518
44981927 44981949 20 + 27760321 MOLM13 viability GATTACGAAATAAAACGGTAGG STK4 ENSG00000101109 -4.586996262991546 [42,41] [0,0] -9 hSpCas9 negative selection 5445519
44995100 44995122 20 - 27760321 MOLM13 viability CCTATCACTGTATTCCGCTTGG STK4 ENSG00000101109 0.9798169363398844 [765,656] [663,895] 7 hSpCas9 negative selection 5445520
44997200 44997222 20 - 27760321 MOLM13 viability AGCTCTGGTTTTCGGAATGTGG STK4 ENSG00000101109 -1.0089999875528126 [568,540] [225,95] -6 hSpCas9 negative selection 5445521
44966506 44966529 20 + 27661255 K562 viability GGGCTCAGGAGGTCCGCGGGAGG STK4 ENSG00000101109 -1.1532080408529894 [633,767] [258,243] -8 dCas9-KRAB negative selection 5514895
44966532 44966555 20 + 27661255 K562 viability GAGCAGTGAGCGGGTCTGGGCGG STK4 ENSG00000101109 -0.03395185683588209 [851,1052] [816,674] -1 dCas9-KRAB negative selection 5514896
44966550 44966573 20 + 27661255 K562 viability GGCGGCTGCTGGCAGCGCCATGG STK4 ENSG00000101109 0.6227557117268958 [253,202] [299,266] 9 dCas9-KRAB negative selection 5514897
44966609 44966632 20 + 27661255 K562 viability GGGCCACTGGCTAAGAGGACGGG STK4 ENSG00000101109 0.10390815383710073 [546,502] [486,420] 3 dCas9-KRAB negative selection 5514898
44966900 44966923 20 + 27661255 K562 viability GCTATCCAAGCAGGGACTCACGG STK4 ENSG00000101109 -0.1461358912788654 [911,914] [667,651] -5 dCas9-KRAB negative selection 5514899
44970491 44970514 20 + 27661255 K562 viability GGACTTTACCAAAAAAACCCTGG STK4 ENSG00000101109 -0.049926892184863236 [870,991] [715,717] -2 dCas9-KRAB negative selection 5514900
44970681 44970704 20 + 27661255 K562 viability GTTCTGTTGATATCAAGTTAAGG STK4 ENSG00000101109 -0.00804048610685193 [319,287] [235,246] 0 dCas9-KRAB negative selection 5514901
44978445 44978468 20 - 27260156 BXPC3 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.26199010279113333 [218] [195,263,309,344] 6 hSpCas9 negative selection 5573594
44966592 44966615 20 - 27260156 BXPC3 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.017672435359061378 [203] [141,229,287,209] 0 hSpCas9 negative selection 5573595
44966567 44966590 20 - 27260156 BXPC3 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.1782517306498877 [498] [633,507,583,636] 4 hSpCas9 negative selection 5573596
44978494 44978517 20 + 27260156 BXPC3 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.02907704282786483 [837] [842,789,952,848] 0 hSpCas9 negative selection 5637849
44972072 44972095 20 + 27260156 BXPC3 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.04583201108907531 [127] [156,156,83,111] -1 hSpCas9 negative selection 5637850
44972118 44972141 20 - 27260156 BXPC3 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.07928358577577577 [226] [218,185,341,264] 1 hSpCas9 negative selection 5637851
44978445 44978468 20 - 27260156 A673 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.4340669132867575 [218] [309,345,358,402] 8 hSpCas9 negative selection 5694845
44966592 44966615 20 - 27260156 A673 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.2785651036786594 [203] [194,142,230,240] -6 hSpCas9 negative selection 5694846
44966567 44966590 20 - 27260156 A673 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.4088544198225153 [498] [873,741,806,765] 8 hSpCas9 negative selection 5694847
44978494 44978517 20 + 27260156 A673 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.03355860464155169 [837] [1235,850,984,1076] 0 hSpCas9 negative selection 5759100
44972072 44972095 20 + 27260156 A673 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.33770233168415387 [127] [232,142,199,206] 7 hSpCas9 negative selection 5759101
44972118 44972141 20 - 27260156 A673 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.043056997822005005 [226] [287,209,276,287] -1 hSpCas9 negative selection 5759102
44978445 44978468 20 - 27260156 A375 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.8769630650769368 [218] [574,610,263,449] 9 hSpCas9 negative selection 5816096
44966592 44966615 20 - 27260156 A375 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.325584520229769 [203] [224,340,337,294] 5 hSpCas9 negative selection 5816097
44966567 44966590 20 - 27260156 A375 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.12414118499343527 [498] [461,891,668,558] 1 hSpCas9 negative selection 5816098
44978494 44978517 20 + 27260156 A375 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.03497964364276329 [837] [1022,1132,945,763] 0 hSpCas9 negative selection 5880351
44972072 44972095 20 + 27260156 A375 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.05581963377924759 [127] [99,177,90,202] -1 hSpCas9 negative selection 5880352
44972118 44972141 20 - 27260156 A375 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.5921850814161127 [226] [388,309,294,569] 8 hSpCas9 negative selection 5880353
44978445 44978468 20 - 27260156 COLO741 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6075973860638237 [218] [568,406,321] 9 hSpCas9 negative selection 5937347
44966592 44966615 20 - 27260156 COLO741 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.11747541239384085 [203] [178,320,216] -3 hSpCas9 negative selection 5937348
44966567 44966590 20 - 27260156 COLO741 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3584125042898317 [498] [792,805,846] 7 hSpCas9 negative selection 5937349
44978494 44978517 20 + 27260156 COLO741 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.09382915993459284 [837] [1324,1090,1032] 2 hSpCas9 negative selection 6001602
44972072 44972095 20 + 27260156 COLO741 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.472455119254265 [127] [223,256,200] 8 hSpCas9 negative selection 6001603
44972118 44972141 20 - 27260156 COLO741 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.21101283794498416 [226] [366,375,270] 4 hSpCas9 negative selection 6001604
44978445 44978468 20 - 27260156 CAL120 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.39625244219972255 [218] [462,351,277] 6 hSpCas9 negative selection 6058598
44966592 44966615 20 - 27260156 CAL120 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.0034322321232609365 [203] [336,167,266] 0 hSpCas9 negative selection 6058599
44966567 44966590 20 - 27260156 CAL120 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.7149644561174049 [498] [1058,687,1310] 9 hSpCas9 negative selection 6058600
44978494 44978517 20 + 27260156 CAL120 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.22156002751314297 [837] [1397,1307,972] 3 hSpCas9 negative selection 6122853
44972072 44972095 20 + 27260156 CAL120 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.18201746623631943 [127] [153,117,150] -3 hSpCas9 negative selection 6122854
44972118 44972141 20 - 27260156 CAL120 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.30068193449785796 [226] [530,292,248] 4 hSpCas9 negative selection 6122855
44978445 44978468 20 - 27260156 CADOES1 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.9935147950036676 [218] [439,421,280,481] 9 hSpCas9 negative selection 6179849
44966592 44966615 20 - 27260156 CADOES1 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.09886099183042463 [203] [181,134,253,135] -2 hSpCas9 negative selection 6179850
44966567 44966590 20 - 27260156 CADOES1 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.25764809859789967 [498] [386,671,606,553] 4 hSpCas9 negative selection 6179851
44978494 44978517 20 + 27260156 CADOES1 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.4055153688018479 [837] [1020,1143,1025,934] 6 hSpCas9 negative selection 6244104
44972072 44972095 20 + 27260156 CADOES1 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.007515303181036437 [127] [88,119,89,176] 0 hSpCas9 negative selection 6244105
44972118 44972141 20 - 27260156 CADOES1 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.027920974177028546 [226] [192,222,205,239] 0 hSpCas9 negative selection 6244106
44978445 44978468 20 - 27260156 EWS502 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.8726495521407007 [218] [356,437,369,547] 9 hSpCas9 negative selection 6301100
44966592 44966615 20 - 27260156 EWS502 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.00930892080096779 [203] [179,180,296,205] 0 hSpCas9 negative selection 6301101
44966567 44966590 20 - 27260156 EWS502 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3697183445908679 [498] [600,743,737,651] 6 hSpCas9 negative selection 6301102
44978494 44978517 20 + 27260156 EWS502 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.21170040131971957 [837] [873,959,1098,1209] 3 hSpCas9 negative selection 6365355
44972072 44972095 20 + 27260156 EWS502 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.01666929469799472 [127] [118,148,114,154] 0 hSpCas9 negative selection 6365356
44972118 44972141 20 - 27260156 EWS502 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.45152014120303463 [226] [277,200,357,500] 7 hSpCas9 negative selection 6365357
44978445 44978468 20 - 27260156 EW8 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.5802482370270857 [218] [398,163,252,260] 8 hSpCas9 negative selection 6422351
44966592 44966615 20 - 27260156 EW8 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.05133097016795274 [203] [167,158,178,176] 0 hSpCas9 negative selection 6422352
44966567 44966590 20 - 27260156 EW8 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.24896698451590338 [498] [738,397,380,447] 4 hSpCas9 negative selection 6422353
44978494 44978517 20 + 27260156 EW8 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.04524157649090821 [837] [767,724,481,697] -1 hSpCas9 negative selection 6486606
44972072 44972095 20 + 27260156 EW8 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.4347859452811562 [127] [300,77,44,169] 7 hSpCas9 negative selection 6486607
44972118 44972141 20 - 27260156 EW8 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.09617143716165799 [226] [208,216,205,153] 1 hSpCas9 negative selection 6486608
44978445 44978468 20 - 27260156 CORL105 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.3149212093949729 [218] [249,342,402,289] 6 hSpCas9 negative selection 6543602
44966592 44966615 20 - 27260156 CORL105 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.08607961568229627 [203] [172,187,240,298] -1 hSpCas9 negative selection 6543603
44966567 44966590 20 - 27260156 CORL105 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.2712455726379174 [498] [815,590,924,528] 5 hSpCas9 negative selection 6543604
44978494 44978517 20 + 27260156 CORL105 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.12387947844309721 [837] [1045,676,1312,639] -2 hSpCas9 negative selection 6607857
44972072 44972095 20 + 27260156 CORL105 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.19459717630974316 [127] [184,194,189,118] 3 hSpCas9 negative selection 6607858
44972118 44972141 20 - 27260156 CORL105 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.14114159583369368 [226] [300,210,255,200] -3 hSpCas9 negative selection 6607859
44978445 44978468 20 - 27260156 HS294T viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.23777980276156108 [218] [97,92,120,84] 3 hSpCas9 negative selection 6664853
44966592 44966615 20 - 27260156 HS294T viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.7772629675262266 [203] [73,44,341,78] 8 hSpCas9 negative selection 6664854
44966567 44966590 20 - 27260156 HS294T viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 -0.1423776374683554 [498] [106,158,193,259] -2 hSpCas9 negative selection 6664855
44978494 44978517 20 + 27260156 HS294T viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.0839872746460385 [837] [280,257,284,420] -1 hSpCas9 negative selection 6729108
44972072 44972095 20 + 27260156 HS294T viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.563484682363474 [127] [42,103,54,95] 7 hSpCas9 negative selection 6729109
44972118 44972141 20 - 27260156 HS294T viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.9226225114012707 [226] [97,326,124,105] 9 hSpCas9 negative selection 6729110
44978445 44978468 20 - 27260156 HCC44 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.9600545559550343 [218] [499,321,563,572] 9 hSpCas9 negative selection 6786104
44966592 44966615 20 - 27260156 HCC44 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.1702685990593118 [203] [190,112,417,146] -3 hSpCas9 negative selection 6786105
44966567 44966590 20 - 27260156 HCC44 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.33746560861546326 [498] [979,604,605,677] 5 hSpCas9 negative selection 6786106
44978494 44978517 20 + 27260156 HCC44 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.05534118137299959 [837] [984,827,1114,1045] 0 hSpCas9 negative selection 6850359
44972072 44972095 20 + 27260156 HCC44 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.21303176758684184 [127] [225,233,72,117] 3 hSpCas9 negative selection 6850360
44972118 44972141 20 - 27260156 HCC44 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.2028641897529122 [226] [298,259,451,203] 3 hSpCas9 negative selection 6850361
44978445 44978468 20 - 27260156 G402 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.014183584568304 [218] [563,149,784,633] 9 hSpCas9 negative selection 6907355
44966592 44966615 20 - 27260156 G402 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.23807870557463273 [203] [212,288,151,194] -3 hSpCas9 negative selection 6907356
44966567 44966590 20 - 27260156 G402 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.5508559357776033 [498] [1026,1100,806,671] 6 hSpCas9 negative selection 6907357
44978494 44978517 20 + 27260156 G402 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.1286081654506427 [837] [925,1537,576,739] -2 hSpCas9 negative selection 6971610
44972072 44972095 20 + 27260156 G402 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 1.023192629245207 [127] [151,479,260,358] 9 hSpCas9 negative selection 6971611
44972118 44972141 20 - 27260156 G402 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.85008032903375 [226] [244,787,351,585] 9 hSpCas9 negative selection 6971612
44978445 44978468 20 - 27260156 L33 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6640452108002262 [218] [263,183,207,345] 9 hSpCas9 negative selection 7028606
44966592 44966615 20 - 27260156 L33 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.7373641310992713 [203] [97,64,69,121] -9 hSpCas9 negative selection 7028607
44966567 44966590 20 - 27260156 L33 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.007212256175500073 [498] [467,214,391,391] 0 hSpCas9 negative selection 7028608
44978494 44978517 20 + 27260156 L33 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.20820066793988234 [837] [885,330,714,1042] 4 hSpCas9 negative selection 7092861
44972072 44972095 20 + 27260156 L33 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.4257497000936896 [127] [235,56,78,184] 8 hSpCas9 negative selection 7092862
44972118 44972141 20 - 27260156 L33 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.13339580754112168 [226] [212,105,102,191] -3 hSpCas9 negative selection 7092863
44978445 44978468 20 - 27260156 K562 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.2989288652164491 [218] [319,236,185,220] 4 hSpCas9 negative selection 7149857
44966592 44966615 20 - 27260156 K562 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.3413769497337624 [203] [162,136,440,171] 4 hSpCas9 negative selection 7149858
44966567 44966590 20 - 27260156 K562 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.17611453254635956 [498] [548,429,515,503] 2 hSpCas9 negative selection 7149859
44978494 44978517 20 + 27260156 K562 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.03811053869512471 [837] [1046,785,559,690] 0 hSpCas9 negative selection 7214112
44972072 44972095 20 + 27260156 K562 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.9139739810709487 [127] [161,158,170,340] 9 hSpCas9 negative selection 7214113
44972118 44972141 20 - 27260156 K562 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.6007350977171968 [226] [578,353,142,183] 7 hSpCas9 negative selection 7214114
44978445 44978468 20 - 27260156 HT29 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.7391654676757481 [218] [448,542,372,420] 9 hSpCas9 negative selection 7271108
44966592 44966615 20 - 27260156 HT29 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.0474490008693238 [203] [302,344,227,111] -1 hSpCas9 negative selection 7271109
44966567 44966590 20 - 27260156 HT29 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.43771543864984674 [498] [934,868,674,814] 8 hSpCas9 negative selection 7271110
44978494 44978517 20 + 27260156 HT29 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.24495701622913713 [837] [1375,1103,1467,912] 5 hSpCas9 negative selection 7335363
44972072 44972095 20 + 27260156 HT29 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.28975302164292915 [127] [215,159,229,156] 5 hSpCas9 negative selection 7335364
44972118 44972141 20 - 27260156 HT29 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.02582948601778834 [226] [303,232,313,234] 0 hSpCas9 negative selection 7335365
44978445 44978468 20 - 27260156 MHHES1 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6387595885482212 [218] [548,339,486,208] 9 hSpCas9 negative selection 7392359
44966592 44966615 20 - 27260156 MHHES1 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.36026717339280845 [203] [107,122,276,187] -6 hSpCas9 negative selection 7392360
44966567 44966590 20 - 27260156 MHHES1 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.28087687555138413 [498] [715,777,712,552] 5 hSpCas9 negative selection 7392361
44978494 44978517 20 + 27260156 MHHES1 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.34780826925965147 [837] [1018,1646,1118,1049] 6 hSpCas9 negative selection 7456614
44972072 44972095 20 + 27260156 MHHES1 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.6653017642028494 [127] [469,127,164,176] 9 hSpCas9 negative selection 7456615
44972118 44972141 20 - 27260156 MHHES1 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.37127095627119955 [226] [406,296,277,336] 6 hSpCas9 negative selection 7456616
44978445 44978468 20 - 27260156 MEWO viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.495517546214306 [218] [352,274,250] 8 hSpCas9 negative selection 7513610
44966592 44966615 20 - 27260156 MEWO viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.5418271999881432 [203] [139,128,125] -8 hSpCas9 negative selection 7513611
44966567 44966590 20 - 27260156 MEWO viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3590664608618198 [498] [719,531,567] 7 hSpCas9 negative selection 7513612
44978494 44978517 20 + 27260156 MEWO viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.0193822194408122 [837] [1044,619,767] 0 hSpCas9 negative selection 7577865
44972072 44972095 20 + 27260156 MEWO viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.3383722106435545 [127] [164,113,177] 7 hSpCas9 negative selection 7577866
44972118 44972141 20 - 27260156 MEWO viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.2630355756459124 [226] [136,206,178] -5 hSpCas9 negative selection 7577867
44978445 44978468 20 - 27260156 LNCAPCLONEFGC viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.4281197820764522 [218] [212,211,413,254] 6 hSpCas9 negative selection 7634861
44966592 44966615 20 - 27260156 LNCAPCLONEFGC viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.058751811641533536 [203] [217,180,198,172] 0 hSpCas9 negative selection 7634862
44966567 44966590 20 - 27260156 LNCAPCLONEFGC viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.374576544862426 [498] [474,582,780,535] 6 hSpCas9 negative selection 7634863
44978494 44978517 20 + 27260156 LNCAPCLONEFGC viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.18063782620247493 [837] [755,530,796,620] -3 hSpCas9 negative selection 7699116
44972072 44972095 20 + 27260156 LNCAPCLONEFGC viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.08934607632416669 [127] [151,47,121,118] -1 hSpCas9 negative selection 7699117
44972118 44972141 20 - 27260156 LNCAPCLONEFGC viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.16944034318628476 [226] [136,260,286,247] 2 hSpCas9 negative selection 7699118
44978445 44978468 20 - 27260156 PANC0327 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.1866569943366885 [218] [304,373,614,474] 9 hSpCas9 negative selection 7756112
44966592 44966615 20 - 27260156 PANC0327 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.3898600270628798 [203] [240,96,155,72] -5 hSpCas9 negative selection 7756113
44966567 44966590 20 - 27260156 PANC0327 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 1.1743224947953883 [498] [950,1523,1005,448] 9 hSpCas9 negative selection 7756114
44978494 44978517 20 + 27260156 PANC0327 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.1301731192481388 [837] [898,845,615,899] 2 hSpCas9 negative selection 7820367
44972072 44972095 20 + 27260156 PANC0327 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.06814412465904285 [127] [53,79,128,169] -1 hSpCas9 negative selection 7820368
44972118 44972141 20 - 27260156 PANC0327 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.17718606053028907 [226] [180,112,213,213] -3 hSpCas9 negative selection 7820369
44978445 44978468 20 - 27260156 NCIH2009 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.37643748241519304 [218] [426,441,326] 5 hSpCas9 negative selection 7877363
44966592 44966615 20 - 27260156 NCIH2009 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.2786227280902356 [203] [309,376,341] 4 hSpCas9 negative selection 7877364
44966567 44966590 20 - 27260156 NCIH2009 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3363858164473485 [498] [989,877,792] 4 hSpCas9 negative selection 7877365
44978494 44978517 20 + 27260156 NCIH2009 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.1314739481214443 [837] [1594,941,773] -2 hSpCas9 negative selection 7941618
44972072 44972095 20 + 27260156 NCIH2009 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.5659390542606699 [127] [79,128,144] -6 hSpCas9 negative selection 7941619
44972118 44972141 20 - 27260156 NCIH2009 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.1794279382205064 [226] [278,307,251] -2 hSpCas9 negative selection 7941620
44978445 44978468 20 - 27260156 NCIH1373 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.7165342009598568 [218] [382,488,331,103] 7 hSpCas9 negative selection 7998614
44966592 44966615 20 - 27260156 NCIH1373 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.09664994849557629 [203] [238,123,172,122] 1 hSpCas9 negative selection 7998615
44966567 44966590 20 - 27260156 NCIH1373 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.39286860191990425 [498] [1466,553,495,142] 4 hSpCas9 negative selection 7998616
44978494 44978517 20 + 27260156 NCIH1373 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.060890607067670355 [837] [830,902,912,333] 0 hSpCas9 negative selection 8062869
44972072 44972095 20 + 27260156 NCIH1373 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.37809522364680204 [127] [259,251,49,49] 4 hSpCas9 negative selection 8062870
44972118 44972141 20 - 27260156 NCIH1373 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.3899499210775538 [226] [123,375,582,51] 4 hSpCas9 negative selection 8062871
44978445 44978468 20 - 27260156 PATU8902 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 1.0626097305520488 [218] [993,475,471,638] 9 hSpCas9 negative selection 8119865
44966592 44966615 20 - 27260156 PATU8902 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.21862577394939908 [203] [463,206,215,477] 2 hSpCas9 negative selection 8119866
44966567 44966590 20 - 27260156 PATU8902 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 1.1372308064806371 [498] [1421,1306,1692,1652] 9 hSpCas9 negative selection 8119867
44978494 44978517 20 + 27260156 PATU8902 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.4252062922253276 [837] [2142,1695,1302,1121] 4 hSpCas9 negative selection 8184120
44972072 44972095 20 + 27260156 PATU8902 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.27380090457525386 [127] [429,249,92,102] 2 hSpCas9 negative selection 8184121
44972118 44972141 20 - 27260156 PATU8902 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.2028466229964464 [226] [476,252,244,525] 2 hSpCas9 negative selection 8184122
44978445 44978468 20 - 27260156 PANC1 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.5028087770402605 [218] [328,359,272,138] 7 hSpCas9 negative selection 8241116
44966592 44966615 20 - 27260156 PANC1 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.48236967216012894 [203] [134,199,105,80] -6 hSpCas9 negative selection 8241117
44966567 44966590 20 - 27260156 PANC1 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.12410761596432532 [498] [441,712,445,332] 2 hSpCas9 negative selection 8241118
44978494 44978517 20 + 27260156 PANC1 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.18656202370715713 [837] [971,958,953,463] 3 hSpCas9 negative selection 8305371
44972072 44972095 20 + 27260156 PANC1 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.6162872446793994 [127] [172,272,130,122] 8 hSpCas9 negative selection 8305372
44972118 44972141 20 - 27260156 PANC1 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.1169802491599905 [226] [198,257,263,142] 1 hSpCas9 negative selection 8305373
44978445 44978468 20 - 27260156 PANC0813 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.39737667657273334 [218] [321,278,403,347] 6 hSpCas9 negative selection 8362367
44966592 44966615 20 - 27260156 PANC0813 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.12776172723798984 [203] [254,156,310,160] -2 hSpCas9 negative selection 8362368
44966567 44966590 20 - 27260156 PANC0813 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.22032296900836035 [498] [740,477,756,755] 3 hSpCas9 negative selection 8362369
44978494 44978517 20 + 27260156 PANC0813 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.061519957761266064 [837] [1002,1250,1013,846] 1 hSpCas9 negative selection 8426622
44972072 44972095 20 + 27260156 PANC0813 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.04005081927803822 [127] [215,198,117,93] 0 hSpCas9 negative selection 8426623
44972118 44972141 20 - 27260156 PANC0813 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.008941385016052239 [226] [219,351,284,201] 0 hSpCas9 negative selection 8426624
44978445 44978468 20 - 27260156 RDES viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6822838220884041 [218] [370,383,442,417] 9 hSpCas9 negative selection 8483618
44966592 44966615 20 - 27260156 RDES viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.04978266009024446 [203] [266,226,212,251] 0 hSpCas9 negative selection 8483619
44966567 44966590 20 - 27260156 RDES viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.24211100832599564 [498] [586,669,633,846] 4 hSpCas9 negative selection 8483620
44978494 44978517 20 + 27260156 RDES viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.08144122304408252 [837] [904,770,1122,1351] 1 hSpCas9 negative selection 8547873
44972072 44972095 20 + 27260156 RDES viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.29373183567319394 [127] [120,73,104,190] -5 hSpCas9 negative selection 8547874
44972118 44972141 20 - 27260156 RDES viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.33612791894335603 [226] [213,312,395,430] 5 hSpCas9 negative selection 8547875
44978445 44978468 20 - 27260156 PC3 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6303871574594915 [218] [273,366,377,331] 9 hSpCas9 negative selection 8604869
44966592 44966615 20 - 27260156 PC3 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.20501904453402697 [203] [97,229,270,157] -4 hSpCas9 negative selection 8604870
44966567 44966590 20 - 27260156 PC3 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.19456307765100966 [498] [315,530,1080,613] 4 hSpCas9 negative selection 8604871
44978494 44978517 20 + 27260156 PC3 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.09701687067552922 [837] [429,722,1659,741] -2 hSpCas9 negative selection 8669124
44972072 44972095 20 + 27260156 PC3 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.11502359390743333 [127] [49,96,298,118] -3 hSpCas9 negative selection 8669125
44972118 44972141 20 - 27260156 PC3 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.3628620374346412 [226] [155,83,325,187] -7 hSpCas9 negative selection 8669126
44978445 44978468 20 - 27260156 PATU8988T viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.20844055267513129 [218] [147,309,296,226] 3 hSpCas9 negative selection 8726120
44966592 44966615 20 - 27260156 PATU8988T viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.14685138761149208 [203] [113,160,260,172] -3 hSpCas9 negative selection 8726121
44966567 44966590 20 - 27260156 PATU8988T viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3560230753540472 [498] [727,813,388,553] 6 hSpCas9 negative selection 8726122
44978494 44978517 20 + 27260156 PATU8988T viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 -0.05289771049961822 [837] [961,710,569,883] -1 hSpCas9 negative selection 8790375
44972072 44972095 20 + 27260156 PATU8988T viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.40502972221987243 [127] [67,162,284,134] 7 hSpCas9 negative selection 8790376
44972118 44972141 20 - 27260156 PATU8988T viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.15694847443587556 [226] [194,209,169,214] -3 hSpCas9 negative selection 8790377
44978445 44978468 20 - 27260156 T47D viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6208223369764565 [218] [439,364,334,433] 9 hSpCas9 negative selection 8847371
44966592 44966615 20 - 27260156 T47D viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.08769592098904488 [203] [292,218,233,267] 1 hSpCas9 negative selection 8847372
44966567 44966590 20 - 27260156 T47D viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.25374954361909696 [498] [691,629,652,806] 5 hSpCas9 negative selection 8847373
44978494 44978517 20 + 27260156 T47D viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.0612817165325914 [837] [1152,1087,931,892] 1 hSpCas9 negative selection 8911626
44972072 44972095 20 + 27260156 T47D viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.5845133440472803 [127] [168,280,179,260] 9 hSpCas9 negative selection 8911627
44972118 44972141 20 - 27260156 T47D viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.2397827188634828 [226] [268,263,375,343] 5 hSpCas9 negative selection 8911628
44978445 44978468 20 - 27260156 SU8686 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.6328699266342991 [218] [358,370,238,370] 9 hSpCas9 negative selection 8968622
44966592 44966615 20 - 27260156 SU8686 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.8281859087378929 [203] [101,110,98,149] -8 hSpCas9 negative selection 8968623
44966567 44966590 20 - 27260156 SU8686 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.09347839555745385 [498] [509,531,465,612] 1 hSpCas9 negative selection 8968624
44978494 44978517 20 + 27260156 SU8686 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.12980484653568258 [837] [1045,782,1006,774] 2 hSpCas9 negative selection 9032877
44972072 44972095 20 + 27260156 SU8686 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.16983796163022702 [127] [151,143,106,168] 3 hSpCas9 negative selection 9032878
44972118 44972141 20 - 27260156 SU8686 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.06985963898396552 [226] [237,203,238,271] 1 hSpCas9 negative selection 9032879
44978445 44978468 20 - 27260156 SKES1 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.41643237550637136 [218] [372,293,271,241] 8 hSpCas9 negative selection 9089873
44966592 44966615 20 - 27260156 SKES1 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.057365636160677136 [203] [172,324,142,156] -1 hSpCas9 negative selection 9089874
44966567 44966590 20 - 27260156 SKES1 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.24588373027140337 [498] [679,582,603,508] 5 hSpCas9 negative selection 9089875
44978494 44978517 20 + 27260156 SKES1 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.3415568239703036 [837] [1500,1028,1019,768] 7 hSpCas9 negative selection 9154128
44972072 44972095 20 + 27260156 SKES1 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.2990984442088436 [127] [171,180,182,101] 6 hSpCas9 negative selection 9154129
44972118 44972141 20 - 27260156 SKES1 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.15717659783663918 [226] [319,321,197,192] 3 hSpCas9 negative selection 9154130
44978445 44978468 20 - 27260156 TOV112D viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.36556699103036516 [218] [397,278,260,202] 7 hSpCas9 negative selection 9211124
44966592 44966615 20 - 27260156 TOV112D viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.003248262017177206 [203] [198,157,336,111] 0 hSpCas9 negative selection 9211125
44966567 44966590 20 - 27260156 TOV112D viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.4022693283467614 [498] [724,777,720,456] 7 hSpCas9 negative selection 9211126
44978494 44978517 20 + 27260156 TOV112D viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.3137649699492716 [837] [1139,1526,830,806] 6 hSpCas9 negative selection 9275379
44972072 44972095 20 + 27260156 TOV112D viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.05196216992293734 [127] [134,277,47,106] 1 hSpCas9 negative selection 9275380
44972118 44972141 20 - 27260156 TOV112D viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.7982493811374503 [226] [333,258,514,432] 9 hSpCas9 negative selection 9275381
44978445 44978468 20 - 27260156 TC71 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.7346016874244723 [218] [325,470,389,375] 9 hSpCas9 negative selection 9332375
44966592 44966615 20 - 27260156 TC71 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 0.09916309919471789 [203] [258,189,279,203] 2 hSpCas9 negative selection 9332376
44966567 44966590 20 - 27260156 TC71 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.3220411537856045 [498] [770,673,510,724] 7 hSpCas9 negative selection 9332377
44978494 44978517 20 + 27260156 TC71 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.15055741616469198 [837] [901,955,991,1149] 4 hSpCas9 negative selection 9396630
44972072 44972095 20 + 27260156 TC71 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 0.3967551412900603 [127] [142,181,158,243] 8 hSpCas9 negative selection 9396631
44972118 44972141 20 - 27260156 TC71 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 -0.31112976084502475 [226] [139,163,241,240] -7 hSpCas9 negative selection 9396632
44978445 44978468 20 - 27260156 TC32 viability AGCTTTGTATACGCTGCCATAGG STK4 ENSG00000101109 0.4710364502692004 [218] [289,214,332,321] 7 hSpCas9 negative selection 9453626
44966592 44966615 20 - 27260156 TC32 viability TGGCCCCTCACCGGCGCGGCGGG STK4 ENSG00000101109 -0.16762022260969633 [203] [166,111,162,256] -3 hSpCas9 negative selection 9453627
44966567 44966590 20 - 27260156 TC32 viability CCTCAGCTGTACCGTCTCCATGG STK4 ENSG00000101109 0.2980251579084818 [498] [607,583,609,456] 5 hSpCas9 negative selection 9453628
44978494 44978517 20 + 27260156 TC32 viability TGCTATTAAGCAAGTTCCTGTGG STK4 ENSG00000101109 0.00173727842310889 [837] [713,464,1179,960] 0 hSpCas9 negative selection 9517881
44972072 44972095 20 + 27260156 TC32 viability TCACAGGCAGCTGAAAAAGTTGG STK4 ENSG00000101109 -0.24928856272240285 [127] [56,108,100,135] -4 hSpCas9 negative selection 9517882
44972118 44972141 20 - 27260156 TC32 viability AAGACATCAAATACTTCTTCTGG STK4 ENSG00000101109 0.3217473105707961 [226] [269,224,345,235] 5 hSpCas9 negative selection 9517883
44966556 44966579 20 + 27869803 HPAFII viability after 27 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.1969507722284789 [464] [305,135,NaN] -1 hSpCas9 negative selection 9577783
44987207 44987230 20 + 27869803 HPAFII viability after 27 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.5037727454691274 [204] [142,160,NaN] 4 hSpCas9 negative selection 9577784
45000454 45000477 20 + 27869803 HPAFII viability after 27 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.6247923160753655 [96] [309,29,NaN] 9 hSpCas9 negative selection 9577785
45001199 45001222 20 + 27869803 HPAFII viability after 27 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.7088430534140826 [441] [453,317,NaN] 6 hSpCas9 negative selection 9577786
45053145 45053168 20 - 27869803 HPAFII viability after 27 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.595755274875989 [245] [315,94,NaN] 5 hSpCas9 negative selection 9577787
45075100 45075123 20 + 27869803 HPAFII viability after 27 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.9118158966268114 [148] [87,2,NaN] -6 hSpCas9 negative selection 9577788
44966556 44966579 20 + 27869803 HPAFII viability after 15 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.09687123571252065 [464] [589,390,NaN] -1 hSpCas9 negative selection 9660232
44987207 44987230 20 + 27869803 HPAFII viability after 15 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.03330670217562742 [204] [300,161,NaN] 0 hSpCas9 negative selection 9660233
45000454 45000477 20 + 27869803 HPAFII viability after 15 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.8714984418909683 [96] [326,105,NaN] 8 hSpCas9 negative selection 9660234
45001199 45001222 20 + 27869803 HPAFII viability after 15 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.1376445250055499 [441] [886,295,NaN] 1 hSpCas9 negative selection 9660235
45053145 45053168 20 - 27869803 HPAFII viability after 15 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 -0.5777028612532867 [245] [297,101,NaN] -6 hSpCas9 negative selection 9660236
45075100 45075123 20 + 27869803 HPAFII viability after 15 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.28130892242739547 [148] [312,120,NaN] 3 hSpCas9 negative selection 9660237
44966556 44966579 20 + 27869803 ASPC1 viability after 36 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.05370725254738934 [870] [598,106,278] 0 hSpCas9 negative selection 9742681
44987207 44987230 20 + 27869803 ASPC1 viability after 36 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.05694439329542733 [378] [203,53,155] 0 hSpCas9 negative selection 9742682
45000454 45000477 20 + 27869803 ASPC1 viability after 36 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 0.36136248191858045 [281] [155,0,203] 3 hSpCas9 negative selection 9742683
45001199 45001222 20 + 27869803 ASPC1 viability after 36 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.27899253382423783 [889] [458,408,289] 3 hSpCas9 negative selection 9742684
45053145 45053168 20 - 27869803 ASPC1 viability after 36 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.1140812750200357 [652] [1011,343,242] 9 hSpCas9 negative selection 9742685
45075100 45075123 20 + 27869803 ASPC1 viability after 36 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -2.1303454087742537 [311] [11,65,0] -9 hSpCas9 negative selection 9742686
44966556 44966579 20 + 27869803 PATU8988S viability after 35 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.4958287206073563 [755] [584,272,NaN] 5 hSpCas9 negative selection 9825130
44987207 44987230 20 + 27869803 PATU8988S viability after 35 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.5466775691095569 [313] [119,52,NaN] -5 hSpCas9 negative selection 9825131
45000454 45000477 20 + 27869803 PATU8988S viability after 35 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.1536790825104717 [209] [261,113,NaN] 9 hSpCas9 negative selection 9825132
45001199 45001222 20 + 27869803 PATU8988S viability after 35 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.21119027119829337 [661] [374,241,NaN] 2 hSpCas9 negative selection 9825133
45053145 45053168 20 - 27869803 PATU8988S viability after 35 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.000356890414605 [553] [383,508,NaN] 8 hSpCas9 negative selection 9825134
45075100 45075123 20 + 27869803 PATU8988S viability after 35 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.6837692084069832 [359] [189,275,NaN] 7 hSpCas9 negative selection 9825135
44966556 44966579 20 + 27869803 PATU8988S viability after 31 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 0.5344260558888583 [755] [484,374,NaN] 6 hSpCas9 negative selection 9907579
44987207 44987230 20 + 27869803 PATU8988S viability after 31 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 -0.5086847640863914 [313] [98,73,NaN] -5 hSpCas9 negative selection 9907580
45000454 45000477 20 + 27869803 PATU8988S viability after 31 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.0134301500231533 [209] [161,177,NaN] 9 hSpCas9 negative selection 9907581
45001199 45001222 20 + 27869803 PATU8988S viability after 31 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.2148130881856749 [661] [253,372,NaN] 2 hSpCas9 negative selection 9907582
45053145 45053168 20 - 27869803 PATU8988S viability after 31 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 1.0692458348797236 [553] [320,644,NaN] 9 hSpCas9 negative selection 9907583
45075100 45075123 20 + 27869803 PATU8988S viability after 31 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 0.24899971947758448 [359] [119,234,NaN] 3 hSpCas9 negative selection 9907584
44966556 44966579 20 + 27869803 HPAFII viability after 35 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.283589750551116 [464] [278,96,NaN] -2 hSpCas9 negative selection 9990028
44987207 44987230 20 + 27869803 HPAFII viability after 35 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.5850467933499192 [204] [221,80,NaN] 4 hSpCas9 negative selection 9990029
45000454 45000477 20 + 27869803 HPAFII viability after 35 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.3794109866754891 [96] [226,15,NaN] 8 hSpCas9 negative selection 9990030
45001199 45001222 20 + 27869803 HPAFII viability after 35 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.9187807288825778 [441] [470,368,NaN] 6 hSpCas9 negative selection 9990031
45053145 45053168 20 - 27869803 HPAFII viability after 35 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.7219996714021882 [245] [338,54,NaN] 5 hSpCas9 negative selection 9990032
45075100 45075123 20 + 27869803 HPAFII viability after 35 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.7909283716810519 [148] [60,23,NaN] -4 hSpCas9 negative selection 9990033
44966556 44966579 20 + 27869803 HPAFII viability after 31 days TGCTGGCAGCGCCATGGAGACGG STK4 ENSG00000101109 -0.41690176768619136 [464] [272,110,NaN] -3 hSpCas9 negative selection 10072477
44987207 44987230 20 + 27869803 HPAFII viability after 31 days ATACACCGAGATATCAAGGCAGG STK4 ENSG00000101109 0.1705402290453608 [204] [184,68,NaN] 1 hSpCas9 negative selection 10072478
45000454 45000477 20 + 27869803 HPAFII viability after 31 days GGATGTGAAACTGAAACGCCAGG STK4 ENSG00000101109 1.904822504089315 [96] [367,24,NaN] 9 hSpCas9 negative selection 10072479
45001199 45001222 20 + 27869803 HPAFII viability after 31 days TCGAGCAGTGGGTGATGAGATGG STK4 ENSG00000101109 0.6232481182148546 [441] [439,318,NaN] 4 hSpCas9 negative selection 10072480
45053145 45053168 20 - 27869803 HPAFII viability after 31 days AGAAAGCGTATCTACACAGCAGG STK4 ENSG00000101109 0.854826164252556 [245] [331,159,NaN] 6 hSpCas9 negative selection 10072481
45075100 45075123 20 + 27869803 HPAFII viability after 31 days GGCAGAAGTACCAGTCCAAGCGG STK4 ENSG00000101109 -0.31005078272599873 [148] [110,19,NaN] -2 hSpCas9 negative selection 10072482
45000468 45000491 20 + 28162770 P31FUJ viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.567221243484938 [173] [137] -5 hSpCas9 negative selection 10244606
44995116 44995139 20 + 28162770 P31FUJ viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.9657888705732145 [226] [520] 9 hSpCas9 negative selection 10244607
45025095 45025118 20 + 28162770 P31FUJ viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.11008550910862996 [163] [207] 1 hSpCas9 negative selection 10244608
44972136 44972159 20 + 28162770 P31FUJ viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.5550125312475802 [222] [384] 6 hSpCas9 negative selection 10244609
44997193 44997216 20 - 28162770 P31FUJ viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 1.3869257144674543 [81] [251] 9 hSpCas9 negative selection 10244610
44997260 44997283 20 + 28162770 P31FUJ viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.8177647051355348 [167] [111] -6 hSpCas9 negative selection 10244611
44995194 44995217 20 + 28162770 P31FUJ viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.14746987670378864 [125] [163] 1 hSpCas9 negative selection 10244612
45001304 45001327 20 + 28162770 P31FUJ viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.1956395463864702 [615] [828] 2 hSpCas9 negative selection 10244613
45025038 45025061 20 + 28162770 P31FUJ viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.41521246684207924 [96] [151] 4 hSpCas9 negative selection 10244614
44966567 44966590 20 + 28162770 P31FUJ viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.2140656418327928 [305] [309] -2 hSpCas9 negative selection 10244615
45000468 45000491 20 + 28162770 TF1 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 NaN [NaN] [295] 1 hSpCas9 negative selection 10413972
44995116 44995139 20 + 28162770 TF1 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 NaN [NaN] [396] 1 hSpCas9 negative selection 10413973
45025095 45025118 20 + 28162770 TF1 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 NaN [NaN] [167] 1 hSpCas9 negative selection 10413974
44972136 44972159 20 + 28162770 TF1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 NaN [NaN] [235] 1 hSpCas9 negative selection 10413975
44997193 44997216 20 - 28162770 TF1 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 NaN [NaN] [68] 1 hSpCas9 negative selection 10413976
44997260 44997283 20 + 28162770 TF1 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 NaN [NaN] [119] 1 hSpCas9 negative selection 10413977
44995194 44995217 20 + 28162770 TF1 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 NaN [NaN] [162] 1 hSpCas9 negative selection 10413978
45001304 45001327 20 + 28162770 TF1 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 NaN [NaN] [451] 1 hSpCas9 negative selection 10413979
45025038 45025061 20 + 28162770 TF1 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 NaN [NaN] [206] 1 hSpCas9 negative selection 10413980
44966567 44966590 20 + 28162770 TF1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 NaN [NaN] [195] 1 hSpCas9 negative selection 10413981
45000468 45000491 20 + 28162770 SKM1 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.566268891694053 [33] [88] 5 hSpCas9 negative selection 10583338
44995116 44995139 20 + 28162770 SKM1 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.13427692454867662 [66] [129] 1 hSpCas9 negative selection 10583339
45025095 45025118 20 + 28162770 SKM1 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -1.0395931330946322 [49] [42] -6 hSpCas9 negative selection 10583340
44972136 44972159 20 + 28162770 SKM1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.3365748708517637 [84] [118] -3 hSpCas9 negative selection 10583341
44997193 44997216 20 - 28162770 SKM1 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.36386484728932844 [39] [90] 3 hSpCas9 negative selection 10583342
44997260 44997283 20 + 28162770 SKM1 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.4409115306664994 [42] [55] -4 hSpCas9 negative selection 10583343
44995194 44995217 20 + 28162770 SKM1 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.4069641987431617 [35] [47] -3 hSpCas9 negative selection 10583344
45001304 45001327 20 + 28162770 SKM1 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.08820163162734862 [115] [217] 0 hSpCas9 negative selection 10583345
45025038 45025061 20 + 28162770 SKM1 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.643664456763493 [37] [42] -5 hSpCas9 negative selection 10583346
44966567 44966590 20 + 28162770 SKM1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.9198490214201499 [60] [56] -6 hSpCas9 negative selection 10583347
45000468 45000491 20 + 28162770 SKM1 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.566268891694053 [33] [88] 5 hSpCas9 negative selection 10752704
44995116 44995139 20 + 28162770 SKM1 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.13427692454867662 [66] [129] 1 hSpCas9 negative selection 10752705
45025095 45025118 20 + 28162770 SKM1 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -1.0395931330946322 [49] [42] -6 hSpCas9 negative selection 10752706
44972136 44972159 20 + 28162770 SKM1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.3365748708517637 [84] [118] -3 hSpCas9 negative selection 10752707
44997193 44997216 20 - 28162770 SKM1 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.36386484728932844 [39] [90] 3 hSpCas9 negative selection 10752708
44997260 44997283 20 + 28162770 SKM1 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.4409115306664994 [42] [55] -4 hSpCas9 negative selection 10752709
44995194 44995217 20 + 28162770 SKM1 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.4069641987431617 [35] [47] -3 hSpCas9 negative selection 10752710
45001304 45001327 20 + 28162770 SKM1 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.08820163162734862 [115] [217] 0 hSpCas9 negative selection 10752711
45025038 45025061 20 + 28162770 SKM1 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.643664456763493 [37] [42] -5 hSpCas9 negative selection 10752712
44966567 44966590 20 + 28162770 SKM1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.9198490214201499 [60] [56] -6 hSpCas9 negative selection 10752713
45000468 45000491 20 + 28162770 PL21 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.4428897488687593 [190] [112] 4 hSpCas9 negative selection 10922070
44995116 44995139 20 + 28162770 PL21 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 -0.22043606833095358 [173] [64] -1 hSpCas9 negative selection 10922071
45025095 45025118 20 + 28162770 PL21 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.13427942458123907 [231] [91] -1 hSpCas9 negative selection 10922072
44972136 44972159 20 + 28162770 PL21 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.4571752797016708 [240] [143] 4 hSpCas9 negative selection 10922073
44997193 44997216 20 - 28162770 PL21 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.967162442511706 [113] [96] 7 hSpCas9 negative selection 10922074
44997260 44997283 20 + 28162770 PL21 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.5761075490895715 [130] [84] 5 hSpCas9 negative selection 10922075
44995194 44995217 20 + 28162770 PL21 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.26283236185322567 [101] [36] -2 hSpCas9 negative selection 10922076
45001304 45001327 20 + 28162770 PL21 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 -0.07670059086950443 [440] [181] 0 hSpCas9 negative selection 10922077
45025038 45025061 20 + 28162770 PL21 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.5247618185459458 [106] [66] 4 hSpCas9 negative selection 10922078
44966567 44966590 20 + 28162770 PL21 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -1.3171360787202615 [228] [39] -7 hSpCas9 negative selection 10922079
45000468 45000491 20 + 28162770 P31FUJ viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.567221243484938 [173] [137] -5 hSpCas9 negative selection 11091436
44995116 44995139 20 + 28162770 P31FUJ viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.9657888705732145 [226] [520] 9 hSpCas9 negative selection 11091437
45025095 45025118 20 + 28162770 P31FUJ viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.11008550910862996 [163] [207] 1 hSpCas9 negative selection 11091438
44972136 44972159 20 + 28162770 P31FUJ viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.5550125312475802 [222] [384] 6 hSpCas9 negative selection 11091439
44997193 44997216 20 - 28162770 P31FUJ viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 1.3869257144674543 [81] [251] 9 hSpCas9 negative selection 11091440
44997260 44997283 20 + 28162770 P31FUJ viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.8177647051355348 [167] [111] -6 hSpCas9 negative selection 11091441
44995194 44995217 20 + 28162770 P31FUJ viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.14746987670378864 [125] [163] 1 hSpCas9 negative selection 11091442
45001304 45001327 20 + 28162770 P31FUJ viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.1956395463864702 [615] [828] 2 hSpCas9 negative selection 11091443
45025038 45025061 20 + 28162770 P31FUJ viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.41521246684207924 [96] [151] 4 hSpCas9 negative selection 11091444
44966567 44966590 20 + 28162770 P31FUJ viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.2140656418327928 [305] [309] -2 hSpCas9 negative selection 11091445
45000468 45000491 20 + 28162770 OCIAML5 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.160819277003626 [108] [175] -1 hSpCas9 negative selection 11260802
44995116 44995139 20 + 28162770 OCIAML5 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 -0.10816492948741435 [165] [277] -1 hSpCas9 negative selection 11260803
45025095 45025118 20 + 28162770 OCIAML5 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.22593594113727622 [116] [246] 2 hSpCas9 negative selection 11260804
44972136 44972159 20 + 28162770 OCIAML5 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.35604162446620313 [173] [401] 3 hSpCas9 negative selection 11260805
44997193 44997216 20 - 28162770 OCIAML5 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 1.252802546989958 [62] [270] 9 hSpCas9 negative selection 11260806
44997260 44997283 20 + 28162770 OCIAML5 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.7328959298571591 [108] [326] 6 hSpCas9 negative selection 11260807
44995194 44995217 20 + 28162770 OCIAML5 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.1391646815882605 [132] [217] -1 hSpCas9 negative selection 11260808
45001304 45001327 20 + 28162770 OCIAML5 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.6404802956357625 [230] [649] 5 hSpCas9 negative selection 11260809
45025038 45025061 20 + 28162770 OCIAML5 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.2097096267226929 [79] [166] 1 hSpCas9 negative selection 11260810
44966567 44966590 20 + 28162770 OCIAML5 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.7235518303413166 [160] [175] -5 hSpCas9 negative selection 11260811
45000468 45000491 20 + 28162770 EOL1 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.3225117574904369 [339] [223] 3 hSpCas9 negative selection 11430168
44995116 44995139 20 + 28162770 EOL1 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.2125799941140582 [266] [162] 2 hSpCas9 negative selection 11430169
45025095 45025118 20 + 28162770 EOL1 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.3872820128806747 [356] [245] 3 hSpCas9 negative selection 11430170
44972136 44972159 20 + 28162770 EOL1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.5683665201294505 [424] [150] -4 hSpCas9 negative selection 11430171
44997193 44997216 20 - 28162770 EOL1 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 1.6950659254477674 [152] [260] 9 hSpCas9 negative selection 11430172
44997260 44997283 20 + 28162770 EOL1 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.7117733527956837 [298] [257] 6 hSpCas9 negative selection 11430173
44995194 44995217 20 + 28162770 EOL1 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.6773300711995156 [126] [106] 6 hSpCas9 negative selection 11430174
45001304 45001327 20 + 28162770 EOL1 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 1.24749507882165 [565] [707] 9 hSpCas9 negative selection 11430175
45025038 45025061 20 + 28162770 EOL1 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 1.6710204514811162 [120] [202] 9 hSpCas9 negative selection 11430176
44966567 44966590 20 + 28162770 EOL1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.7034834510425076 [271] [87] -5 hSpCas9 negative selection 11430177
45000468 45000491 20 + 28162770 MOLM13 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.18736754898194383 [248] [204] 1 hSpCas9 negative selection 11599534
44995116 44995139 20 + 28162770 MOLM13 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.7461101911930487 [314] [381] 5 hSpCas9 negative selection 11599535
45025095 45025118 20 + 28162770 MOLM13 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.4500413802116542 [243] [240] 3 hSpCas9 negative selection 11599536
44972136 44972159 20 + 28162770 MOLM13 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 0.46373773827411147 [347] [346] 3 hSpCas9 negative selection 11599537
44997193 44997216 20 - 28162770 MOLM13 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 2.3307394161938864 [101] [370] 9 hSpCas9 negative selection 11599538
44997260 44997283 20 + 28162770 MOLM13 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.9408742300327022 [182] [253] 7 hSpCas9 negative selection 11599539
44995194 44995217 20 + 28162770 MOLM13 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.06262533515420096 [233] [161] 0 hSpCas9 negative selection 11599540
45001304 45001327 20 + 28162770 MOLM13 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 -0.29426612108292904 [596] [351] -2 hSpCas9 negative selection 11599541
45025038 45025061 20 + 28162770 MOLM13 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 0.4061603917928726 [190] [182] 3 hSpCas9 negative selection 11599542
44966567 44966590 20 + 28162770 MOLM13 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.23814435306973666 [322] [197] -1 hSpCas9 negative selection 11599543
45000468 45000491 20 + 28162770 HEL viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.41170895202201946 [188] [90] -3 hSpCas9 negative selection 11768900
44995116 44995139 20 + 28162770 HEL viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.23819370653915545 [273] [206] 2 hSpCas9 negative selection 11768901
45025095 45025118 20 + 28162770 HEL viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 0.13000465883437987 [223] [156] 1 hSpCas9 negative selection 11768902
44972136 44972159 20 + 28162770 HEL viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.1381860510470403 [310] [180] -1 hSpCas9 negative selection 11768903
44997193 44997216 20 - 28162770 HEL viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.3797044261665632 [137] [114] 3 hSpCas9 negative selection 11768904
44997260 44997283 20 + 28162770 HEL viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.6036390123114165 [186] [181] 5 hSpCas9 negative selection 11768905
44995194 44995217 20 + 28162770 HEL viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.8384031542415465 [178] [204] 7 hSpCas9 negative selection 11768906
45001304 45001327 20 + 28162770 HEL viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 -0.1081659531237229 [519] [308] -1 hSpCas9 negative selection 11768907
45025038 45025061 20 + 28162770 HEL viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 1.404054287582312 [140] [238] 9 hSpCas9 negative selection 11768908
44966567 44966590 20 + 28162770 HEL viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.5152135277758796 [269] [120] -3 hSpCas9 negative selection 11768909
45000468 45000491 20 + 28162770 MV411 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.17048245702919002 [166] [124] -1 hSpCas9 negative selection 11938266
44995116 44995139 20 + 28162770 MV411 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 1.1452259392840414 [211] [394] 8 hSpCas9 negative selection 11938267
45025095 45025118 20 + 28162770 MV411 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.4821105718209478 [193] [116] -4 hSpCas9 negative selection 11938268
44972136 44972159 20 + 28162770 MV411 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.5386648220462323 [218] [126] -4 hSpCas9 negative selection 11938269
44997193 44997216 20 - 28162770 MV411 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.443580072961398 [102] [117] 4 hSpCas9 negative selection 11938270
44997260 44997283 20 + 28162770 MV411 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 -0.45743441367357773 [162] [99] -3 hSpCas9 negative selection 11938271
44995194 44995217 20 + 28162770 MV411 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.43186212192020257 [87] [99] 4 hSpCas9 negative selection 11938272
45001304 45001327 20 + 28162770 MV411 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.06735593430429176 [391] [345] 0 hSpCas9 negative selection 11938273
45025038 45025061 20 + 28162770 MV411 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 1.2926263245490308 [109] [226] 9 hSpCas9 negative selection 11938274
44966567 44966590 20 + 28162770 MV411 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 0.26278551511621123 [186] [188] 2 hSpCas9 negative selection 11938275
45000468 45000491 20 + 28162770 MONOMAC1 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 0.5805707316039984 [118] [203] 5 hSpCas9 negative selection 12107632
44995116 44995139 20 + 28162770 MONOMAC1 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 -0.31965613372350943 [134] [123] -3 hSpCas9 negative selection 12107633
45025095 45025118 20 + 28162770 MONOMAC1 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.7880738621903943 [118] [78] -6 hSpCas9 negative selection 12107634
44972136 44972159 20 + 28162770 MONOMAC1 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -1.1081031186392654 [172] [91] -7 hSpCas9 negative selection 12107635
44997193 44997216 20 - 28162770 MONOMAC1 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 2.178601834572576 [57] [300] 9 hSpCas9 negative selection 12107636
44997260 44997283 20 + 28162770 MONOMAC1 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.7187501490373611 [96] [182] 7 hSpCas9 negative selection 12107637
44995194 44995217 20 + 28162770 MONOMAC1 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.9022935814984216 [74] [45] -6 hSpCas9 negative selection 12107638
45001304 45001327 20 + 28162770 MONOMAC1 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.007233556002469443 [308] [355] 0 hSpCas9 negative selection 12107639
45025038 45025061 20 + 28162770 MONOMAC1 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 1.2235388357607202 [64] [173] 9 hSpCas9 negative selection 12107640
44966567 44966590 20 + 28162770 MONOMAC1 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.08338006526398642 [121] [131] 0 hSpCas9 negative selection 12107641
45000468 45000491 20 + 28162770 OCIAML2 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 -0.6495999662874806 [29] [105] -5 hSpCas9 negative selection 12276998
44995116 44995139 20 + 28162770 OCIAML2 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.7037410812313434 [35] [324] 7 hSpCas9 negative selection 12276999
45025095 45025118 20 + 28162770 OCIAML2 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 1.1336980003459263 [36] [449] 9 hSpCas9 negative selection 12277000
44972136 44972159 20 + 28162770 OCIAML2 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.8331999046268695 [62] [195] -5 hSpCas9 negative selection 12277001
44997193 44997216 20 - 28162770 OCIAML2 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 -0.011198206604863925 [15] [87] 0 hSpCas9 negative selection 12277002
44997260 44997283 20 + 28162770 OCIAML2 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.22597803130790395 [28] [187] 2 hSpCas9 negative selection 12277003
44995194 44995217 20 + 28162770 OCIAML2 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 -0.8076648125197317 [17] [56] -5 hSpCas9 negative selection 12277004
45001304 45001327 20 + 28162770 OCIAML2 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 -0.7261891105138087 [76] [257] -5 hSpCas9 negative selection 12277005
45025038 45025061 20 + 28162770 OCIAML2 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.018933855384469123 [16] [92] 0 hSpCas9 negative selection 12277006
44966567 44966590 20 + 28162770 OCIAML2 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 0.06186525558485939 [27] [161] 0 hSpCas9 negative selection 12277007
45000468 45000491 20 + 28162770 OCIAML3 viability AACGCCAGGAATCCCAGCAGCGG STK4 ENSG00000101109 1.2837366096248388 [39] [293] 9 hSpCas9 negative selection 12446364
44995116 44995139 20 + 28162770 OCIAML3 viability GATAGGAACACCATTTTGGATGG STK4 ENSG00000101109 0.4826136412787493 [54] [231] 4 hSpCas9 negative selection 12446365
45025095 45025118 20 + 28162770 OCIAML3 viability GATTGGAAAATACCACAGGATGG STK4 ENSG00000101109 -0.23916492296406566 [51] [132] -2 hSpCas9 negative selection 12446366
44972136 44972159 20 + 28162770 OCIAML3 viability GTCTTAGAGAAACTTGGAGAAGG STK4 ENSG00000101109 -0.8791648570560973 [91] [150] -6 hSpCas9 negative selection 12446367
44997193 44997216 20 - 28162770 OCIAML3 viability GGTTTTCGGAATGTGGGAGGAGG STK4 ENSG00000101109 0.5707371220124692 [30] [138] 5 hSpCas9 negative selection 12446368
44997260 44997283 20 + 28162770 OCIAML3 viability TTGTAAAGAGCCCTGAGCAGAGG STK4 ENSG00000101109 0.8784801311385804 [39] [221] 7 hSpCas9 negative selection 12446369
44995194 44995217 20 + 28162770 OCIAML3 viability GGGAATAACTGCCATAGAAATGG STK4 ENSG00000101109 0.4306544139101061 [28] [117] 4 hSpCas9 negative selection 12446370
45001304 45001327 20 + 28162770 OCIAML3 viability CACCATGGTGATCAATGCAGAGG STK4 ENSG00000101109 0.04158093346696079 [111] [347] 0 hSpCas9 negative selection 12446371
45025038 45025061 20 + 28162770 OCIAML3 viability GAAAACCAGATCAACAGCTTTGG STK4 ENSG00000101109 -0.054848829216131656 [31] [92] 0 hSpCas9 negative selection 12446372
44966567 44966590 20 + 28162770 OCIAML3 viability CCATGGAGACGGTACAGCTGAGG STK4 ENSG00000101109 -0.26058390659897146 [49] [125] -2 hSpCas9 negative selection 12446373