Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 112755
• Symbol: STX1B
• Description: syntaxin 1B

DataSource: http://genomecrispr.dkfz.de/#!/results/STX1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
30996964	30996987	16	-	26472758	Jiyoye	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	0.466984776741177	[188]	[196]	3	hSpCas9	negative selection	158503
30997501	30997524	16	+	26472758	Jiyoye	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	-0.48034988923571387	[36]	[19]	-3	hSpCas9	negative selection	158504
30997546	30997569	16	-	26472758	Jiyoye	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.5731958117451941	[72]	[36]	-4	hSpCas9	negative selection	158505
30997029	30997052	16	-	26472758	Jiyoye	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.7442103687834438	[18]	[23]	5	hSpCas9	negative selection	158506
30993130	30993153	16	-	26472758	Jiyoye	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	2.5771003829481858	[23]	[107]	9	hSpCas9	negative selection	158507
31001579	31001602	16	-	26472758	Jiyoye	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.06140054466414327	[121]	[95]	0	hSpCas9	negative selection	158508
31000982	31001005	16	-	26472758	Jiyoye	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.6125878733155564	[293]	[144]	-4	hSpCas9	negative selection	158509
30993207	30993230	16	-	26472758	Jiyoye	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.10739779132388483	[59]	[41]	-1	hSpCas9	negative selection	158510
31010385	31010408	16	-	26472758	Jiyoye	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.05925207808556632	[27]	[21]	0	hSpCas9	negative selection	158511
31010370	31010393	16	-	26472758	Jiyoye	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.5949905418440748	[186]	[212]	4	hSpCas9	negative selection	158512
30996964	30996987	16	-	26472758	KBM7	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.8166302975194158	[885,694]	[200,216]	-6	hSpCas9	negative selection	349621
30997501	30997524	16	+	26472758	KBM7	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.6181668232478351	[234,214]	[191,135]	6	hSpCas9	negative selection	349622
30997546	30997569	16	-	26472758	KBM7	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.0284151128146376	[248,247]	[124,114]	0	hSpCas9	negative selection	349623
30997029	30997052	16	-	26472758	KBM7	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.9656196725480124	[75,81]	[50,92]	9	hSpCas9	negative selection	349624
30993130	30993153	16	-	26472758	KBM7	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	1.0517193211053186	[338,220]	[270,265]	9	hSpCas9	negative selection	349625
31001579	31001602	16	-	26472758	KBM7	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.3353987183427385	[711,603]	[303,190]	-3	hSpCas9	negative selection	349626
31000982	31001005	16	-	26472758	KBM7	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.020314646334465336	[1148,758]	[525,353]	0	hSpCas9	negative selection	349627
30993207	30993230	16	-	26472758	KBM7	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	1.1480423748195199	[253,285]	[455,130]	9	hSpCas9	negative selection	349628
31010385	31010408	16	-	26472758	KBM7	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.2878870627067245	[127,145]	[87,71]	3	hSpCas9	negative selection	349629
31010370	31010393	16	-	26472758	KBM7	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.621243718407313	[1102,821]	[295,286]	-5	hSpCas9	negative selection	349630
30996964	30996987	16	-	26472758	Raji	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.6010756311036124	[450]	[68]	-5	hSpCas9	negative selection	540739
30997501	30997524	16	+	26472758	Raji	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.4973300536896128	[57]	[18]	5	hSpCas9	negative selection	540740
30997546	30997569	16	-	26472758	Raji	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.7406012047019768	[97]	[37]	7	hSpCas9	negative selection	540741
30997029	30997052	16	-	26472758	Raji	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.16396706373996683	[99]	[25]	1	hSpCas9	negative selection	540742
30993130	30993153	16	-	26472758	Raji	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	1.0988215218701756	[168]	[83]	8	hSpCas9	negative selection	540743
31001579	31001602	16	-	26472758	Raji	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.19182448301367933	[314]	[63]	-2	hSpCas9	negative selection	540744
31000982	31001005	16	-	26472758	Raji	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.039034713184083136	[486]	[109]	0	hSpCas9	negative selection	540745
30993207	30993230	16	-	26472758	Raji	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.8510437821138139	[128]	[53]	7	hSpCas9	negative selection	540746
31010385	31010408	16	-	26472758	Raji	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.1377571844171182	[46]	[23]	8	hSpCas9	negative selection	540747
31010370	31010393	16	-	26472758	Raji	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.1907684298732606	[520]	[137]	1	hSpCas9	negative selection	540748
30996964	30996987	16	-	26472758	K562	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.4274518382778744	[649]	[407]	-3	hSpCas9	negative selection	731857
30997501	30997524	16	+	26472758	K562	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	2.01287686923619	[144]	[493]	9	hSpCas9	negative selection	731858
30997546	30997569	16	-	26472758	K562	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	1.5292575038185894	[196]	[479]	9	hSpCas9	negative selection	731859
30997029	30997052	16	-	26472758	K562	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-1.4925468664997592	[119]	[35]	-6	hSpCas9	negative selection	731860
30993130	30993153	16	-	26472758	K562	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.6034998209712753	[229]	[294]	5	hSpCas9	negative selection	731861
31001579	31001602	16	-	26472758	K562	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.7939871349728884	[570]	[277]	-5	hSpCas9	negative selection	731862
31000982	31001005	16	-	26472758	K562	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.18093606259791029	[841]	[626]	-1	hSpCas9	negative selection	731863
30993207	30993230	16	-	26472758	K562	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	1.3995377943333531	[184]	[411]	9	hSpCas9	negative selection	731864
31010385	31010408	16	-	26472758	K562	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.390096182862082	[159]	[353]	9	hSpCas9	negative selection	731865
31010370	31010393	16	-	26472758	K562	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.6258099826963637	[769]	[1002]	5	hSpCas9	negative selection	731866
30993207	30993230	16	-	26627737	DLD1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.10433672700535879	[945]	[476,242,241]	1	hSpCas9	negative selection	793838
30993454	30993477	16	-	26627737	DLD1	viability	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	0.15230098210454734	[441]	[179,169,116]	1	hSpCas9	negative selection	793839
30996727	30996750	16	-	26627737	DLD1	viability	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.06683502166603819	[537]	[120,163,233]	0	hSpCas9	negative selection	793840
30996973	30996996	16	-	26627737	DLD1	viability	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-1.670860169800903	[841]	[69,109,70]	-8	hSpCas9	negative selection	793841
30997549	30997572	16	-	26627737	DLD1	viability	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.30786201335274377	[858]	[314,246,106]	-3	hSpCas9	negative selection	793842
31001549	31001572	16	+	26627737	DLD1	viability	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.5641000192032078	[748]	[266,125,90]	-5	hSpCas9	negative selection	793843
30993207	30993230	16	-	26627737	GBM cells	viability after 5 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.0125706566812529	[426]	[234,226]	0	hSpCas9	negative selection	876153
30993454	30993477	16	-	26627737	GBM cells	viability after 5 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.11732676612152523	[267]	[151,112]	-2	hSpCas9	negative selection	876154
30996727	30996750	16	-	26627737	GBM cells	viability after 5 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.6323128540316995	[242]	[231,171]	8	hSpCas9	negative selection	876155
30996973	30996996	16	-	26627737	GBM cells	viability after 5 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.2490621537229819	[317]	[173,112]	-4	hSpCas9	negative selection	876156
30997549	30997572	16	-	26627737	GBM cells	viability after 5 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.03690487795801123	[537]	[341,249]	0	hSpCas9	negative selection	876157
31001549	31001572	16	+	26627737	GBM cells	viability after 5 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.028482376157474565	[309]	[148,176]	0	hSpCas9	negative selection	876158
30993207	30993230	16	-	26627737	GBM cells	viability after 13 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.14744610013296122	[426]	[233,274]	2	hSpCas9	negative selection	958468
30993454	30993477	16	-	26627737	GBM cells	viability after 13 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.05910452157051842	[267]	[186,100]	0	hSpCas9	negative selection	958469
30996727	30996750	16	-	26627737	GBM cells	viability after 13 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	1.048142494077317	[242]	[238,299]	9	hSpCas9	negative selection	958470
30996973	30996996	16	-	26627737	GBM cells	viability after 13 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.4140534618026932	[317]	[150,111]	-5	hSpCas9	negative selection	958471
30997549	30997572	16	-	26627737	GBM cells	viability after 13 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.39153664087777895	[537]	[431,342]	5	hSpCas9	negative selection	958472
31001549	31001572	16	+	26627737	GBM cells	viability after 13 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.25650254915714116	[309]	[265,147]	3	hSpCas9	negative selection	958473
30993207	30993230	16	-	26627737	GBM cells	viability after 21 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.3152351514206235	[426]	[308,269]	3	hSpCas9	negative selection	1040783
30993454	30993477	16	-	26627737	GBM cells	viability after 21 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.2676552000962196	[267]	[133,108]	-2	hSpCas9	negative selection	1040784
30996727	30996750	16	-	26627737	GBM cells	viability after 21 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	1.0163568566994654	[242]	[265,267]	8	hSpCas9	negative selection	1040785
30996973	30996996	16	-	26627737	GBM cells	viability after 21 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-1.2981092478243759	[317]	[75,64]	-8	hSpCas9	negative selection	1040786
30997549	30997572	16	-	26627737	GBM cells	viability after 21 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.5610958262044006	[537]	[460,403]	6	hSpCas9	negative selection	1040787
31001549	31001572	16	+	26627737	GBM cells	viability after 21 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.42600898038339075	[309]	[116,132]	-4	hSpCas9	negative selection	1040788
30993207	30993230	16	-	26627737	RPE1	viability after 9 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.4131464577964231	[2027]	[347,642]	-3	hSpCas9	negative selection	1123098
30993454	30993477	16	-	26627737	RPE1	viability after 9 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.7452112891330352	[1000]	[72,333]	-5	hSpCas9	negative selection	1123099
30996727	30996750	16	-	26627737	RPE1	viability after 9 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.3593228744268173	[551]	[253,179]	2	hSpCas9	negative selection	1123100
30996973	30996996	16	-	26627737	RPE1	viability after 9 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.5080541642438946	[1672]	[297,458]	-4	hSpCas9	negative selection	1123101
30997549	30997572	16	-	26627737	RPE1	viability after 9 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.697877526684149	[2144]	[282,582]	-5	hSpCas9	negative selection	1123102
31001549	31001572	16	+	26627737	RPE1	viability after 9 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.5396014756832539	[1239]	[301,221]	-4	hSpCas9	negative selection	1123103
30993207	30993230	16	-	26627737	RPE1	viability after 12 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.07575077979077038	[2027]	[581,565]	0	hSpCas9	negative selection	1205413
30993454	30993477	16	-	26627737	RPE1	viability after 12 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.6345817570069308	[1000]	[95,254]	-4	hSpCas9	negative selection	1205414
30996727	30996750	16	-	26627737	RPE1	viability after 12 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.15315952244120046	[551]	[178,149]	1	hSpCas9	negative selection	1205415
30996973	30996996	16	-	26627737	RPE1	viability after 12 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.6801798839441332	[1672]	[161,405]	-5	hSpCas9	negative selection	1205416
30997549	30997572	16	-	26627737	RPE1	viability after 12 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.2573336559458186	[2144]	[452,512]	-2	hSpCas9	negative selection	1205417
31001549	31001572	16	+	26627737	RPE1	viability after 12 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-1.1964130552617107	[1239]	[208,77]	-7	hSpCas9	negative selection	1205418
30993207	30993230	16	-	26627737	RPE1	viability after 15 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.610589731416363	[2027]	[250,495]	-4	hSpCas9	negative selection	1287728
30993454	30993477	16	-	26627737	RPE1	viability after 15 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.4082874071529309	[1000]	[248,178]	-3	hSpCas9	negative selection	1287729
30996727	30996750	16	-	26627737	RPE1	viability after 15 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.2741191578530516	[551]	[254,124]	1	hSpCas9	negative selection	1287730
30996973	30996996	16	-	26627737	RPE1	viability after 15 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.5664125789733793	[1672]	[145,486]	-4	hSpCas9	negative selection	1287731
30997549	30997572	16	-	26627737	RPE1	viability after 15 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.3219141731661599	[2144]	[545,426]	-2	hSpCas9	negative selection	1287732
31001549	31001572	16	+	26627737	RPE1	viability after 15 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.9147605321352886	[1239]	[238,134]	-5	hSpCas9	negative selection	1287733
30993207	30993230	16	-	26627737	RPE1	viability after 18 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.11646742641739904	[2027]	[514,493]	0	hSpCas9	negative selection	1370043
30993454	30993477	16	-	26627737	RPE1	viability after 18 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	0.0664477634767271	[1000]	[249,317]	0	hSpCas9	negative selection	1370044
30996727	30996750	16	-	26627737	RPE1	viability after 18 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.8808966909646971	[551]	[414,123]	5	hSpCas9	negative selection	1370045
30996973	30996996	16	-	26627737	RPE1	viability after 18 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.28383109017056984	[1672]	[322,421]	-2	hSpCas9	negative selection	1370046
30997549	30997572	16	-	26627737	RPE1	viability after 18 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.9068038821949959	[2144]	[213,409]	-5	hSpCas9	negative selection	1370047
31001549	31001572	16	+	26627737	RPE1	viability after 18 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-1.7839375705891025	[1239]	[145,44]	-8	hSpCas9	negative selection	1370048
30993207	30993230	16	-	26627737	HeLa	viability after 8 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.02094141976184416	[572]	[413,195,188]	0	hSpCas9	negative selection	1452358
30993454	30993477	16	-	26627737	HeLa	viability after 8 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	0.11305732466080763	[375]	[242,104,195]	1	hSpCas9	negative selection	1452359
30996727	30996750	16	-	26627737	HeLa	viability after 8 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.6904327013852283	[317]	[228,260,183]	6	hSpCas9	negative selection	1452360
30996973	30996996	16	-	26627737	HeLa	viability after 8 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.4756544793234137	[378]	[270,253,175]	4	hSpCas9	negative selection	1452361
30997549	30997572	16	-	26627737	HeLa	viability after 8 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.37010388395106164	[989]	[202,297,460]	-4	hSpCas9	negative selection	1452362
31001549	31001572	16	+	26627737	HeLa	viability after 8 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.1542331686805699	[520]	[289,190,281]	1	hSpCas9	negative selection	1452363
30993207	30993230	16	-	26627737	HeLa	viability after 12 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.17388502858927357	[572]	[210,169,252]	-1	hSpCas9	negative selection	1534673
30993454	30993477	16	-	26627737	HeLa	viability after 12 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	0.2930501647916627	[375]	[263,145,167]	2	hSpCas9	negative selection	1534674
30996727	30996750	16	-	26627737	HeLa	viability after 12 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.45197490785697997	[317]	[144,191,199]	4	hSpCas9	negative selection	1534675
30996973	30996996	16	-	26627737	HeLa	viability after 12 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.13664191133747333	[378]	[25,189,202]	-1	hSpCas9	negative selection	1534676
30997549	30997572	16	-	26627737	HeLa	viability after 12 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.5034525456160002	[989]	[315,218,338]	-4	hSpCas9	negative selection	1534677
31001549	31001572	16	+	26627737	HeLa	viability after 12 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.0038916139072235345	[520]	[417,88,159]	0	hSpCas9	negative selection	1534678
30993207	30993230	16	-	26627737	HeLa	viability after 15 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.5033635638161789	[572]	[543,201,235]	4	hSpCas9	negative selection	1616988
30993454	30993477	16	-	26627737	HeLa	viability after 15 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.2742601892247699	[375]	[170,46,163]	-2	hSpCas9	negative selection	1616989
30996727	30996750	16	-	26627737	HeLa	viability after 15 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.7495331790387363	[317]	[194,146,318]	6	hSpCas9	negative selection	1616990
30996973	30996996	16	-	26627737	HeLa	viability after 15 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	1.0102980706484967	[378]	[122,389,430]	7	hSpCas9	negative selection	1616991
30997549	30997572	16	-	26627737	HeLa	viability after 15 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.47483865496092925	[989]	[291,335,237]	-4	hSpCas9	negative selection	1616992
31001549	31001572	16	+	26627737	HeLa	viability after 15 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.9028323280569505	[520]	[175,19,145]	-7	hSpCas9	negative selection	1616993
30993207	30993230	16	-	26627737	HeLa	viability after 18 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.5483771930421111	[572]	[375,178,235]	4	hSpCas9	negative selection	1699303
30993454	30993477	16	-	26627737	HeLa	viability after 18 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.18380382352768604	[375]	[124,45,163]	-1	hSpCas9	negative selection	1699304
30996727	30996750	16	-	26627737	HeLa	viability after 18 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.7576393314147438	[317]	[136,116,318]	6	hSpCas9	negative selection	1699305
30996973	30996996	16	-	26627737	HeLa	viability after 18 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	1.019639280982951	[378]	[79,330,430]	7	hSpCas9	negative selection	1699306
30997549	30997572	16	-	26627737	HeLa	viability after 18 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.472017458926267	[989]	[193,281,237]	-4	hSpCas9	negative selection	1699307
31001549	31001572	16	+	26627737	HeLa	viability after 18 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.827293557374571	[520]	[127,18,145]	-6	hSpCas9	negative selection	1699308
30993207	30993230	16	-	26627737	HCT116	viability after 6 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.27543947159314563	[1175]	[86,188]	-1	hSpCas9	negative selection	1781618
30993454	30993477	16	-	26627737	HCT116	viability after 6 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.42599833428005607	[692]	[73,84]	-2	hSpCas9	negative selection	1781619
30996727	30996750	16	-	26627737	HCT116	viability after 6 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.9002757511869534	[614]	[45,54]	-5	hSpCas9	negative selection	1781620
30996973	30996996	16	-	26627737	HCT116	viability after 6 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.5011800513280106	[1075]	[270,221]	3	hSpCas9	negative selection	1781621
30997549	30997572	16	-	26627737	HCT116	viability after 6 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.4008260386314015	[1109]	[39,182]	-2	hSpCas9	negative selection	1781622
31001549	31001572	16	+	26627737	HCT116	viability after 6 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.407383131707492	[865]	[72,118]	-2	hSpCas9	negative selection	1781623
30993207	30993230	16	-	26627737	HCT116	viability after 8 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.25012655727301014	[643]	[253,396,243]	-3	hSpCas9	negative selection	1863933
30993454	30993477	16	-	26627737	HCT116	viability after 8 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.5063764900861711	[442]	[140,202,170]	-6	hSpCas9	negative selection	1863934
30996727	30996750	16	-	26627737	HCT116	viability after 8 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.12175120884369674	[313]	[162,268,132]	1	hSpCas9	negative selection	1863935
30996973	30996996	16	-	26627737	HCT116	viability after 8 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.3463169521433913	[485]	[233,157,239]	-4	hSpCas9	negative selection	1863936
30997549	30997572	16	-	26627737	HCT116	viability after 8 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	1.0084314991471215	[315]	[298,486,264]	8	hSpCas9	negative selection	1863937
31001549	31001572	16	+	26627737	HCT116	viability after 8 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.44546674326170477	[441]	[146,210,177]	-5	hSpCas9	negative selection	1863938
30993207	30993230	16	-	26627737	HCT116	viability after 9 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.773054620580581	[1175]	[463,593]	5	hSpCas9	negative selection	1946248
30993454	30993477	16	-	26627737	HCT116	viability after 9 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-1.9101318165745842	[692]	[46,50]	-8	hSpCas9	negative selection	1946249
30996727	30996750	16	-	26627737	HCT116	viability after 9 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.5414608620845697	[614]	[123,103]	-4	hSpCas9	negative selection	1946250
30996973	30996996	16	-	26627737	HCT116	viability after 9 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.4226388489539855	[1075]	[396,69]	-3	hSpCas9	negative selection	1946251
30997549	30997572	16	-	26627737	HCT116	viability after 9 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.21348808905514516	[1109]	[263,248]	-1	hSpCas9	negative selection	1946252
31001549	31001572	16	+	26627737	HCT116	viability after 9 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.9242016313004444	[865]	[65,165]	-6	hSpCas9	negative selection	1946253
30993207	30993230	16	-	26627737	HCT116	viability after 12 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.05412084700912878	[643]	[474,298,267]	0	hSpCas9	negative selection	2028563
30993454	30993477	16	-	26627737	HCT116	viability after 12 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.5050553400350428	[442]	[172,190,127]	-5	hSpCas9	negative selection	2028564
30996727	30996750	16	-	26627737	HCT116	viability after 12 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.5611749090156566	[313]	[161,65,101]	-6	hSpCas9	negative selection	2028565
30996973	30996996	16	-	26627737	HCT116	viability after 12 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.12085777537990006	[485]	[289,242,166]	-1	hSpCas9	negative selection	2028566
30997549	30997572	16	-	26627737	HCT116	viability after 12 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.9559610429372057	[315]	[253,386,332]	7	hSpCas9	negative selection	2028567
31001549	31001572	16	+	26627737	HCT116	viability after 12 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.33364931400357645	[441]	[256,118,168]	-4	hSpCas9	negative selection	2028568
30993207	30993230	16	-	26627737	HCT116	viability after 15 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.15034550300029204	[643]	[357,537,329]	1	hSpCas9	negative selection	2110878
30993454	30993477	16	-	26627737	HCT116	viability after 15 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.4511535435802698	[442]	[318,114,140]	-5	hSpCas9	negative selection	2110879
30996727	30996750	16	-	26627737	HCT116	viability after 15 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.08496265327670502	[313]	[152,186,167]	-1	hSpCas9	negative selection	2110880
30996973	30996996	16	-	26627737	HCT116	viability after 15 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.300786065860113	[485]	[270,257,156]	-3	hSpCas9	negative selection	2110881
30997549	30997572	16	-	26627737	HCT116	viability after 15 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	1.230494059570619	[315]	[425,382,467]	8	hSpCas9	negative selection	2110882
31001549	31001572	16	+	26627737	HCT116	viability after 15 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.9254150161837604	[441]	[171,130,102]	-7	hSpCas9	negative selection	2110883
30993207	30993230	16	-	26627737	HCT116	viability after 18 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.04439066852187712	[643]	[336,327,235]	0	hSpCas9	negative selection	2193193
30993454	30993477	16	-	26627737	HCT116	viability after 18 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	0.10266538555313875	[442]	[210,253,222]	0	hSpCas9	negative selection	2193194
30996727	30996750	16	-	26627737	HCT116	viability after 18 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.11232846151694109	[313]	[107,181,127]	-1	hSpCas9	negative selection	2193195
30996973	30996996	16	-	26627737	HCT116	viability after 18 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.033570646354584066	[485]	[192,400,110]	0	hSpCas9	negative selection	2193196
30997549	30997572	16	-	26627737	HCT116	viability after 18 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	1.595864907762591	[315]	[373,500,509]	9	hSpCas9	negative selection	2193197
31001549	31001572	16	+	26627737	HCT116	viability after 18 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.5964943631282259	[441]	[77,226,111]	-5	hSpCas9	negative selection	2193198
31010598	31010621	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGCATCGCCACCGCAGCCCGG	STX1B	ENSG00000099365	-2.3533774218751056	[533,24]	[16,4]	-9	dCas9-VP64	positive selection	2461787
31010622	31010645	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGCACAGGGTAGGATGGAGGG	STX1B	ENSG00000099365	1.1393712605184168	[82,1]	[34,3]	4	dCas9-VP64	positive selection	2461788
31010579	31010602	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGCCGGGCTCGGCTCTGCCGG	STX1B	ENSG00000099365	0.020466890485267203	[129,63]	[12,28]	0	dCas9-VP64	positive selection	2461789
31010598	31010621	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGCATCGCCACCGCAGCCCGG	STX1B	ENSG00000099365	-0.6471602952584761	[158,14]	[29,6]	-6	dCas9-VP64	positive selection	2557042
31010622	31010645	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGCACAGGGTAGGATGGAGGG	STX1B	ENSG00000099365	0.04195112635646048	[43,25]	[10,11]	0	dCas9-VP64	positive selection	2557043
31010579	31010602	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGCCGGGCTCGGCTCTGCCGG	STX1B	ENSG00000099365	0.4228377070180407	[24,41]	[18,8]	3	dCas9-VP64	positive selection	2557044
30997029	30997052	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.003698084245748967	[4,4]	[4,2]	0	hSpCas9	positive selection	3024493
31001177	31001200	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	-0.4584913340184046	[3,3]	[2,1]	-6	hSpCas9	positive selection	3024494
31001564	31001587	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	0.011116943235685989	[3,2]	[3,1]	0	hSpCas9	positive selection	3024495
31001550	31001573	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.4461947934691368	[2,3]	[2,0]	-6	hSpCas9	positive selection	3024496
30997029	30997052	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.26212088431606395	[4,4]	[4,1]	-4	hSpCas9	positive selection	3092351
31001177	31001200	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	1.4238046061807135	[3,3]	[3,8]	9	hSpCas9	positive selection	3092352
31001564	31001587	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	-0.39151637955515173	[3,3]	[3,0]	-6	hSpCas9	positive selection	3092353
31001550	31001573	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.2973892154737244	[2,2]	[3,0]	-4	hSpCas9	positive selection	3092354
31001546	31001569		-	24336571	A375	resistance to PLX after 7 days	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.1094972064100489	[16,19]	[19,18]	3	hSpCas9	positive selection	3148182
31010385	31010408		-	24336571	A375	resistance to PLX after 7 days	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.313557555499909	[9,9]	[14,10]	8	hSpCas9	positive selection	3148183
31001546	31001569		-	24336571	A375	resistance to PLX after 14 days	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	-0.3140713655798355	[16,22]	[6,6]	-4	hSpCas9	positive selection	3205975
31010385	31010408		-	24336571	A375	resistance to PLX after 14 days	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.3585112007989958	[7,10]	[6,3]	3	hSpCas9	positive selection	3205976
31001546	31001569		-	24336571	A375	viability after 7 days	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.25505586305426114	[15]	[16,19]	4	hSpCas9	negative selection	3263768
31010385	31010408		-	24336571	A375	viability after 7 days	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.025643177249201787	[10]	[9,9]	0	hSpCas9	negative selection	3263769
31001546	31001569		-	24336571	A375	viability after 14 days	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.41052269071116015	[15]	[16,22]	5	hSpCas9	negative selection	3321561
31010385	31010408		-	24336571	A375	viability after 14 days	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.10115006389764136	[10]	[7,10]	-1	hSpCas9	negative selection	3321562
31001115	31001138	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-1.0691032756764678	[320,320]	[0,0]	-7	hSpCas9	positive selection	3395533
31001579	31001602	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3395534
31001179	31001202	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3395535
30997029	30997052	16	-	26780180	HT29	viability (Avana library 4 designs)	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	1.03222363254457	[]	[]	4	hSpCas9	negative selection	3463184
31001177	31001200	16	-	26780180	HT29	viability (Avana library 4 designs)	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	2.41102988017495	[]	[]	8	hSpCas9	negative selection	3463185
31001564	31001587	16	-	26780180	HT29	viability (Avana library 4 designs)	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	2.08890119726717	[]	[]	7	hSpCas9	negative selection	3463186
31001549	31001572	16	+	26780180	HT29	viability (Avana library 4 designs)	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	1.91655695943908	[]	[]	7	hSpCas9	negative selection	3463187
31001549	31001572	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	2.05083662483267	[]	[]	3	hSpCas9	negative selection	3565108
31001177	31001200	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	3.13420008413719	[]	[]	5	hSpCas9	negative selection	3565109
31001564	31001587	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	4.12259030152673	[]	[]	6	hSpCas9	negative selection	3565110
30997029	30997052	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	2.24637548797039	[]	[]	3	hSpCas9	negative selection	3565111
30996966	30996989	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	3.56686337350028	[]	[]	5	hSpCas9	negative selection	3565112
31001154	31001177	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	1.6665080562681	[]	[]	2	hSpCas9	negative selection	3565113
31001549	31001572	16	+	26780180	A375	viability (Avana lentiGuide)	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	5.11361810697174	[]	[]	4	hSpCas9	negative selection	3673767
31001177	31001200	16	-	26780180	A375	viability (Avana lentiGuide)	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	3.17106312147921	[]	[]	3	hSpCas9	negative selection	3673768
31001564	31001587	16	-	26780180	A375	viability (Avana lentiGuide)	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	0.69566283403992	[]	[]	0	hSpCas9	negative selection	3673769
30997029	30997052	16	-	26780180	A375	viability (Avana lentiGuide)	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.196341241428061	[]	[]	0	hSpCas9	negative selection	3673770
30996966	30996989	16	+	26780180	A375	viability (Avana lentiGuide)	GCTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	2.27022946168416	[]	[]	2	hSpCas9	negative selection	3673771
31001154	31001177	16	-	26780180	A375	viability (Avana lentiGuide)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-2.16810028874215	[]	[]	-4	hSpCas9	negative selection	3673772
31001549	31001572	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.014125286414141541	[4]	[5,3]	0	hSpCas9	positive selection	3782374
31001177	31001200	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	0.10584977254727607	[5]	[5,5]	2	hSpCas9	positive selection	3782375
31001564	31001587	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	0.21535812481284883	[4]	[5,4]	6	hSpCas9	positive selection	3782376
30997029	30997052	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.21463432224234782	[5]	[6,6]	6	hSpCas9	positive selection	3782377
30996966	30996989	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.43040982394900973	[5]	[6,8]	9	hSpCas9	positive selection	3782378
31001154	31001177	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.026171791797923116	[4]	[4,4]	0	hSpCas9	positive selection	3782379
31001549	31001572	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.4269297423248418	[5]	[2,2]	-5	hSpCas9	positive selection	3890981
31001177	31001200	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCCAGGTGGAAGAGATCCGGGG	STX1B	ENSG00000099365	-0.8103036047770388	[5]	[2,1]	-7	hSpCas9	positive selection	3890982
31001564	31001587	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGAGGAGGTGGTCCACGTGG	STX1B	ENSG00000099365	-0.519108752294225	[4]	[2,2]	-6	hSpCas9	positive selection	3890983
30997029	30997052	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.1807091395986276	[6]	[6,6]	4	hSpCas9	positive selection	3890984
30996966	30996989	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.10867257684066747	[6]	[5,5]	2	hSpCas9	positive selection	3890985
31001154	31001177	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.31238542551237514	[4]	[4,5]	8	hSpCas9	positive selection	3890986
31001115	31001138	16	-	26780180	A375	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	1.1435453167642	[]	[]	6	hSpCas9	negative selection	4000645
31001546	31001569	16	-	26780180	A375	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.804716662978683	[]	[]	3	hSpCas9	negative selection	4000646
31001154	31001177	16	-	26780180	A375	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.7803791291719	[]	[]	3	hSpCas9	negative selection	4000647
31001579	31001602	16	-	26780180	A375	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	1.25938367153179	[]	[]	6	hSpCas9	negative selection	4000648
31010385	31010408	16	-	26780180	A375	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.25109927857613	[]	[]	6	hSpCas9	negative selection	4000649
31001179	31001202	16	-	26780180	A375	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	1.14613070983782	[]	[]	6	hSpCas9	negative selection	4000650
31001115	31001138	16	-	26780180	HT29	viability (GeCKOv2 library)	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	2.01863439460448	[]	[]	9	hSpCas9	negative selection	4108611
31001546	31001569	16	-	26780180	HT29	viability (GeCKOv2 library)	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.805632970285928	[]	[]	3	hSpCas9	negative selection	4108612
31001154	31001177	16	-	26780180	HT29	viability (GeCKOv2 library)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.608830837075179	[]	[]	2	hSpCas9	negative selection	4108613
31001579	31001602	16	-	26780180	HT29	viability (GeCKOv2 library)	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	1.60218776821796	[]	[]	8	hSpCas9	negative selection	4108614
31010385	31010408	16	-	26780180	HT29	viability (GeCKOv2 library)	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.633083213122547	[]	[]	2	hSpCas9	negative selection	4108615
31001179	31001202	16	-	26780180	HT29	viability (GeCKOv2 library)	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	2.38864763651439	[]	[]	9	hSpCas9	negative selection	4108616
31001546	31001569	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.35010211401834557	[3]	[3,2]	8	hSpCas9	positive selection	4174429
31010385	31010408	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.3573688324883697	[3]	[2,2]	8	hSpCas9	positive selection	4174430
31001546	31001569	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	1.0392586136410007	[3]	[3,2,1,3]	7	hSpCas9	positive selection	4238451
31010385	31010408	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.04270082164827843	[3]	[0,0,4,0]	0	hSpCas9	positive selection	4238452
31001154	31001177	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.4430226068892109	[1]	[0,0]	-7	hSpCas9	positive selection	4301263
31001546	31001569	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.016350337921505642	[2]	[2,1]	0	hSpCas9	positive selection	4301264
31010385	31010408	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.2369278397917535	[2]	[2,0]	-5	hSpCas9	positive selection	4301265
31001115	31001138	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.19114421931740833	[3]	[3,1]	-4	hSpCas9	positive selection	4365518
31001579	31001602	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.2946253689962916	[2]	[2,1]	6	hSpCas9	positive selection	4365519
31001179	31001202	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.39381660197478724	[2]	[1,1]	-7	hSpCas9	positive selection	4365520
30996967	30996989	16	+	27760321	OCIAML3	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.9026489534138441	[427,323]	[497,606]	9	hSpCas9	negative selection	4444170
30996991	30997013	16	-	27760321	OCIAML3	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.7559357964746571	[462,337]	[194,168]	-6	hSpCas9	negative selection	4444171
30997560	30997582	16	+	27760321	OCIAML3	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.12247901208942447	[787,730]	[530,564]	-1	hSpCas9	negative selection	4444172
31000991	31001013	16	-	27760321	OCIAML3	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.8847306547273486	[177,182]	[220,314]	8	hSpCas9	negative selection	4444173
31001154	31001176	16	-	27760321	OCIAML3	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.4962751515795355	[537,473]	[289,266]	-5	hSpCas9	negative selection	4444174
30996967	30996989	16	+	27760321	OCIAML2	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.13566483251261147	[427,323]	[242,447]	1	hSpCas9	negative selection	4527633
30996991	30997013	16	-	27760321	OCIAML2	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.6260155770129063	[462,337]	[175,249]	-6	hSpCas9	negative selection	4527634
30997560	30997582	16	+	27760321	OCIAML2	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	0.15045805992789396	[787,730]	[669,697]	2	hSpCas9	negative selection	4527635
31000991	31001013	16	-	27760321	OCIAML2	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.49946309864908667	[177,182]	[199,216]	6	hSpCas9	negative selection	4527636
31001154	31001176	16	-	27760321	OCIAML2	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.06251811866530019	[537,473]	[357,434]	-1	hSpCas9	negative selection	4527637
30996967	30996989	16	+	27760321	MV411	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.89486265742057	[427,323]	[270,737]	6	hSpCas9	negative selection	4611096
30996991	30997013	16	-	27760321	MV411	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.7108708846325427	[462,337]	[75,285]	-5	hSpCas9	negative selection	4611097
30997560	30997582	16	+	27760321	MV411	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	0.03880958417346736	[787,730]	[472,577]	0	hSpCas9	negative selection	4611098
31000991	31001013	16	-	27760321	MV411	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	2.036224747511585	[177,182]	[638,267]	9	hSpCas9	negative selection	4611099
31001154	31001176	16	-	27760321	MV411	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.10482464105704839	[537,473]	[104,738]	0	hSpCas9	negative selection	4611100
30996967	30996989	16	+	27760321	HL60	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.6454864594698024	[427,323]	[528,420]	7	hSpCas9	negative selection	4694559
30996991	30997013	16	-	27760321	HL60	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.6211176584658272	[462,337]	[166,256]	-6	hSpCas9	negative selection	4694560
30997560	30997582	16	+	27760321	HL60	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	0.3042423014856154	[787,730]	[690,845]	4	hSpCas9	negative selection	4694561
31000991	31001013	16	-	27760321	HL60	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.498420726347642	[177,182]	[149,271]	6	hSpCas9	negative selection	4694562
31001154	31001176	16	-	27760321	HL60	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.5810576622339684	[537,473]	[671,558]	7	hSpCas9	negative selection	4694563
30996967	30996989	16	+	27760321	HT1080	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.29271870717536747	[323,252]	[188,87]	1	hSpCas9	negative selection	4778022
30996991	30997013	16	-	27760321	HT1080	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.1467250271493781	[337,263]	[116,149]	0	hSpCas9	negative selection	4778023
30997560	30997582	16	+	27760321	HT1080	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.060487027151675754	[730,570]	[252,243]	0	hSpCas9	negative selection	4778024
31000991	31001013	16	-	27760321	HT1080	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	-0.5424094653235549	[182,142]	[56,30]	-2	hSpCas9	negative selection	4778025
31001154	31001176	16	-	27760321	HT1080	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	1.0214953441617014	[473,369]	[188,507]	5	hSpCas9	negative selection	4778026
30996967	30996989	16	+	27760321	HT29	viability after 7 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.6143978041283336	[323,252]	[826,733,190]	8	hSpCas9	negative selection	4861485
30996991	30997013	16	-	27760321	HT29	viability after 7 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.7013574682438681	[337,263]	[698,665,534]	9	hSpCas9	negative selection	4861486
30997560	30997582	16	+	27760321	HT29	viability after 7 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.1404562003119657	[730,570]	[950,803,555]	-2	hSpCas9	negative selection	4861487
31000991	31001013	16	-	27760321	HT29	viability after 7 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.6766324799059253	[182,142]	[481,192,349]	8	hSpCas9	negative selection	4861488
31001154	31001176	16	-	27760321	HT29	viability after 7 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.05172779851099768	[473,369]	[518,589,461]	0	hSpCas9	negative selection	4861489
30996967	30996989	16	+	27760321	HT29	viability after 25 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.36288224502560357	[323,252]	[385,392,502]	4	hSpCas9	negative selection	4944948
30996991	30997013	16	-	27760321	HT29	viability after 25 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.09478346558049555	[337,263]	[492,298,293]	0	hSpCas9	negative selection	4944949
30997560	30997582	16	+	27760321	HT29	viability after 25 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.3281518444631355	[730,570]	[515,542,737]	-3	hSpCas9	negative selection	4944950
31000991	31001013	16	-	27760321	HT29	viability after 25 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.8717048418398865	[182,142]	[398,411,191]	8	hSpCas9	negative selection	4944951
31001154	31001176	16	-	27760321	HT29	viability after 25 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.3563467004947165	[473,369]	[550,621,689]	4	hSpCas9	negative selection	4944952
30996967	30996989	16	+	27760321	HT29	viability after 22 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.7413512822958066	[323,252]	[651,476,540]	8	hSpCas9	negative selection	5028411
30996991	30997013	16	-	27760321	HT29	viability after 22 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.41100146100504764	[337,263]	[513,582,287]	4	hSpCas9	negative selection	5028412
30997560	30997582	16	+	27760321	HT29	viability after 22 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.6966808581547999	[730,570]	[387,556,449]	-5	hSpCas9	negative selection	5028413
31000991	31001013	16	-	27760321	HT29	viability after 22 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	-0.23738189074573124	[182,142]	[142,179,156]	-2	hSpCas9	negative selection	5028414
31001154	31001176	16	-	27760321	HT29	viability after 22 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.4333413990084902	[473,369]	[867,617,482]	5	hSpCas9	negative selection	5028415
30996967	30996989	16	+	27760321	HT29	viability after 19 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.6680543044431668	[323,252]	[476,497,589]	6	hSpCas9	negative selection	5111874
30996991	30997013	16	-	27760321	HT29	viability after 19 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.26570847354884425	[337,263]	[272,817,145]	2	hSpCas9	negative selection	5111875
30997560	30997582	16	+	27760321	HT29	viability after 19 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.549227032855351	[730,570]	[492,455,572]	-5	hSpCas9	negative selection	5111876
31000991	31001013	16	-	27760321	HT29	viability after 19 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.4853222946650906	[182,142]	[273,271,238]	5	hSpCas9	negative selection	5111877
31001154	31001176	16	-	27760321	HT29	viability after 19 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.296436257629097	[473,369]	[792,526,482]	3	hSpCas9	negative selection	5111878
30996967	30996989	16	+	27760321	HT29	viability after 16 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.43711087276197824	[323,252]	[424,430,453]	5	hSpCas9	negative selection	5195337
30996991	30997013	16	-	27760321	HT29	viability after 16 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.13257429934395865	[337,263]	[549,276,299]	1	hSpCas9	negative selection	5195338
30997560	30997582	16	+	27760321	HT29	viability after 16 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.18683768874603368	[730,570]	[420,751,722]	-2	hSpCas9	negative selection	5195339
31000991	31001013	16	-	27760321	HT29	viability after 16 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.37809821374080255	[182,142]	[273,218,221]	4	hSpCas9	negative selection	5195340
31001154	31001176	16	-	27760321	HT29	viability after 16 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.19846036367945788	[473,369]	[922,588,147]	2	hSpCas9	negative selection	5195341
30996967	30996989	16	+	27760321	HT29	viability after 13 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.2504531666949036	[323,252]	[381,389,420]	3	hSpCas9	negative selection	5278800
30996991	30997013	16	-	27760321	HT29	viability after 13 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.08109054027466212	[337,263]	[198,416,371]	-1	hSpCas9	negative selection	5278801
30997560	30997582	16	+	27760321	HT29	viability after 13 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.6677684365183257	[730,570]	[364,407,642]	-6	hSpCas9	negative selection	5278802
31000991	31001013	16	-	27760321	HT29	viability after 13 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	0.2058942946069946	[182,142]	[382,87,184]	2	hSpCas9	negative selection	5278803
31001154	31001176	16	-	27760321	HT29	viability after 13 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.3396358341148529	[473,369]	[739,512,605]	4	hSpCas9	negative selection	5278804
30996967	30996989	16	+	27760321	HT29	viability after 10 days	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.6040289389233877	[323,252]	[639,556,447]	7	hSpCas9	negative selection	5362263
30996991	30997013	16	-	27760321	HT29	viability after 10 days	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	0.41590343088488635	[337,263]	[506,555,443]	5	hSpCas9	negative selection	5362264
30997560	30997582	16	+	27760321	HT29	viability after 10 days	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.5428981013002263	[730,570]	[656,318,687]	-6	hSpCas9	negative selection	5362265
31000991	31001013	16	-	27760321	HT29	viability after 10 days	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	-0.2797822340459559	[182,142]	[116,271,117]	-4	hSpCas9	negative selection	5362266
31001154	31001176	16	-	27760321	HT29	viability after 10 days	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.2722607930936719	[473,369]	[454,859,600]	3	hSpCas9	negative selection	5362267
30996967	30996989	16	+	27760321	MOLM13	viability	CTGGATCCGGTCCTTGCAGCGG	STX1B	ENSG00000099365	0.4177241966025382	[427,323]	[178,367]	3	hSpCas9	negative selection	5445726
30996991	30997013	16	-	27760321	MOLM13	viability	CGCGACCCAGTCCAAGTACCGG	STX1B	ENSG00000099365	-0.9063627690055532	[462,337]	[160,83]	-5	hSpCas9	negative selection	5445727
30997560	30997582	16	+	27760321	MOLM13	viability	ATGCTTTGCTCGATCGCTGCGG	STX1B	ENSG00000099365	-0.3425080896448254	[787,730]	[209,446]	-2	hSpCas9	negative selection	5445728
31000991	31001013	16	-	27760321	MOLM13	viability	CTCCCCTCAGAGACCAAACAGG	STX1B	ENSG00000099365	1.375495042452246	[177,182]	[360,183]	8	hSpCas9	negative selection	5445729
31001154	31001176	16	-	27760321	MOLM13	viability	TGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	1.8073350209315677	[537,473]	[1571,507]	9	hSpCas9	negative selection	5445730
31010618	31010641	16	+	27661255	K562	viability	GGCTGCGGCACAGGGTAGGATGG	STX1B	ENSG00000099365	-0.022723465828466793	[1055,1064]	[978,709]	-1	dCas9-KRAB	negative selection	5515041
31010622	31010645	16	+	27661255	K562	viability	GCGGCACAGGGTAGGATGGAGGG	STX1B	ENSG00000099365	0.15237268402335769	[1234,1127]	[1217,907]	5	dCas9-KRAB	negative selection	5515042
31010256	31010279	16	-	27661255	K562	viability	GGGGCGAAGGATGAGATCGGAGG	STX1B	ENSG00000099365	0.2053250826866191	[1384,1394]	[1401,1175]	7	dCas9-KRAB	negative selection	5515043
31010317	31010340	16	-	27661255	K562	viability	GGGCGGGACCCCAATATTGGGGG	STX1B	ENSG00000099365	0.47819027812094284	[233,258]	[296,253]	9	dCas9-KRAB	negative selection	5515044
31001154	31001177	16	-	27260156	BXPC3	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.2300397533875329	[86]	[114,116,118,68]	5	hSpCas9	negative selection	5573723
31001546	31001569	16	-	27260156	BXPC3	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5327663260356384	[307]	[371,471,519,512]	9	hSpCas9	negative selection	5573724
31010385	31010408	16	-	27260156	BXPC3	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.5030336006381181	[302]	[384,351,487,599]	9	hSpCas9	negative selection	5573725
31001115	31001138	16	-	27260156	BXPC3	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.14198196834041243	[733]	[782,726,859,1050]	3	hSpCas9	negative selection	5637978
31001579	31001602	16	-	27260156	BXPC3	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.008441058260515666	[267]	[289,304,232,295]	0	hSpCas9	negative selection	5637979
31001179	31001202	16	-	27260156	BXPC3	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.13249558618950272	[437]	[470,512,525,496]	3	hSpCas9	negative selection	5637980
31001154	31001177	16	-	27260156	A673	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.08673063453962726	[86]	[169,93,62,124]	2	hSpCas9	negative selection	5694974
31001546	31001569	16	-	27260156	A673	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.432624660585484	[307]	[575,466,457,504]	8	hSpCas9	negative selection	5694975
31010385	31010408	16	-	27260156	A673	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.18671498918049645	[302]	[419,368,395,475]	4	hSpCas9	negative selection	5694976
31001115	31001138	16	-	27260156	A673	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.03715692056928377	[733]	[1067,801,1000,756]	0	hSpCas9	negative selection	5759229
31001579	31001602	16	-	27260156	A673	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.07116628655769619	[267]	[374,287,282,415]	1	hSpCas9	negative selection	5759230
31001179	31001202	16	-	27260156	A673	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.010835085027788224	[437]	[653,534,395,549]	0	hSpCas9	negative selection	5759231
31001154	31001177	16	-	27260156	A375	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.24308215448865944	[86]	[82,128,68,69]	-4	hSpCas9	negative selection	5816225
31001546	31001569	16	-	27260156	A375	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5569486711168271	[307]	[637,577,483,433]	7	hSpCas9	negative selection	5816226
31010385	31010408	16	-	27260156	A375	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.008642052970279201	[302]	[358,422,265,365]	0	hSpCas9	negative selection	5816227
31001115	31001138	16	-	27260156	A375	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.14657652897287898	[733]	[912,1108,1062,752]	2	hSpCas9	negative selection	5880480
31001579	31001602	16	-	27260156	A375	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.2746560294739512	[267]	[347,336,262,114]	-4	hSpCas9	negative selection	5880481
31001179	31001202	16	-	27260156	A375	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.257274623543389	[437]	[379,512,401,426]	-4	hSpCas9	negative selection	5880482
31001154	31001177	16	-	27260156	COLO741	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.2528755709349588	[86]	[119,142,132]	5	hSpCas9	negative selection	5937476
31001546	31001569	16	-	27260156	COLO741	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.3810773660835114	[307]	[444,645,444]	7	hSpCas9	negative selection	5937477
31010385	31010408	16	-	27260156	COLO741	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.23354855800032315	[302]	[483,484,401]	5	hSpCas9	negative selection	5937478
31001115	31001138	16	-	27260156	COLO741	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.16272192290882015	[733]	[1232,931,1000]	3	hSpCas9	negative selection	6001731
31001579	31001602	16	-	27260156	COLO741	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.008447576416934277	[267]	[444,350,251]	0	hSpCas9	negative selection	6001732
31001179	31001202	16	-	27260156	COLO741	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.13414790050058703	[437]	[610,512,419]	-3	hSpCas9	negative selection	6001733
31001154	31001177	16	-	27260156	CAL120	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.1831733868730132	[86]	[24,39,285]	2	hSpCas9	negative selection	6058727
31001546	31001569	16	-	27260156	CAL120	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.7276327306291316	[307]	[859,574,504]	9	hSpCas9	negative selection	6058728
31010385	31010408	16	-	27260156	CAL120	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.24142560444700023	[302]	[497,185,299]	-4	hSpCas9	negative selection	6058729
31001115	31001138	16	-	27260156	CAL120	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.19194662070822632	[733]	[1105,1041,991]	3	hSpCas9	negative selection	6122982
31001579	31001602	16	-	27260156	CAL120	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.9292478490123127	[267]	[133,146,236]	-8	hSpCas9	negative selection	6122983
31001179	31001202	16	-	27260156	CAL120	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.30293575915212584	[437]	[564,348,429]	-4	hSpCas9	negative selection	6122984
31001154	31001177	16	-	27260156	CADOES1	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.4704864918408238	[86]	[26,54,109,40]	-7	hSpCas9	negative selection	6179978
31001546	31001569	16	-	27260156	CADOES1	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.6540023144865723	[307]	[387,433,532,447]	9	hSpCas9	negative selection	6179979
31010385	31010408	16	-	27260156	CADOES1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.19142999187557364	[302]	[595,173,275,236]	3	hSpCas9	negative selection	6179980
31001115	31001138	16	-	27260156	CADOES1	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.01617648905241953	[733]	[625,601,698,776]	0	hSpCas9	negative selection	6244233
31001579	31001602	16	-	27260156	CADOES1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.28468358672921845	[267]	[231,149,238,196]	-5	hSpCas9	negative selection	6244234
31001179	31001202	16	-	27260156	CADOES1	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.15122869775289105	[437]	[421,286,339,419]	-3	hSpCas9	negative selection	6244235
31001154	31001177	16	-	27260156	EWS502	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.17622581232319723	[86]	[87,80,58,97]	-3	hSpCas9	negative selection	6301229
31001546	31001569	16	-	27260156	EWS502	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.3945154872200137	[307]	[427,340,449,503]	7	hSpCas9	negative selection	6301230
31010385	31010408	16	-	27260156	EWS502	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.0329354324657648	[302]	[287,218,482,333]	0	hSpCas9	negative selection	6301231
31001115	31001138	16	-	27260156	EWS502	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.2626319529495156	[733]	[770,963,716,1317]	4	hSpCas9	negative selection	6365484
31001579	31001602	16	-	27260156	EWS502	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.019916301082428922	[267]	[270,194,315,380]	0	hSpCas9	negative selection	6365485
31001179	31001202	16	-	27260156	EWS502	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.33707277527691065	[437]	[334,343,431,361]	-5	hSpCas9	negative selection	6365486
31001154	31001177	16	-	27260156	EW8	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.027898527426345687	[86]	[41,62,70,96]	0	hSpCas9	negative selection	6422480
31001546	31001569	16	-	27260156	EW8	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.4191588436253363	[307]	[395,217,358,362]	7	hSpCas9	negative selection	6422481
31010385	31010408	16	-	27260156	EW8	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.2449331829636009	[302]	[182,286,165,196]	-4	hSpCas9	negative selection	6422482
31001115	31001138	16	-	27260156	EW8	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.07657836494568315	[733]	[395,645,514,942]	1	hSpCas9	negative selection	6486735
31001579	31001602	16	-	27260156	EW8	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.10875241455671336	[267]	[286,115,183,229]	-2	hSpCas9	negative selection	6486736
31001179	31001202	16	-	27260156	EW8	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.40697021385786897	[437]	[322,232,243,279]	-6	hSpCas9	negative selection	6486737
31001154	31001177	16	-	27260156	CORL105	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.12752146808349218	[86]	[92,137,91,48]	-2	hSpCas9	negative selection	6543731
31001546	31001569	16	-	27260156	CORL105	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.37576025970114046	[307]	[424,503,523,424]	7	hSpCas9	negative selection	6543732
31010385	31010408	16	-	27260156	CORL105	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.2531756039399503	[302]	[268,376,315,228]	-5	hSpCas9	negative selection	6543733
31001115	31001138	16	-	27260156	CORL105	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.11251633753948276	[733]	[747,607,906,934]	-2	hSpCas9	negative selection	6607986
31001579	31001602	16	-	27260156	CORL105	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.09413193158143696	[267]	[205,398,433,153]	-2	hSpCas9	negative selection	6607987
31001179	31001202	16	-	27260156	CORL105	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.20010872665791002	[437]	[443,420,567,371]	-4	hSpCas9	negative selection	6607988
31001154	31001177	16	-	27260156	HS294T	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.49415740458115875	[86]	[22,10,32,29]	-6	hSpCas9	negative selection	6664982
31001546	31001569	16	-	27260156	HS294T	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	1.0762964872929008	[307]	[205,298,216,290]	9	hSpCas9	negative selection	6664983
31010385	31010408	16	-	27260156	HS294T	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.22642805295736157	[302]	[69,103,108,123]	-3	hSpCas9	negative selection	6664984
31001115	31001138	16	-	27260156	HS294T	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.10917018170885695	[733]	[219,304,334,384]	1	hSpCas9	negative selection	6729237
31001579	31001602	16	-	27260156	HS294T	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.4818527371669826	[267]	[62,57,63,120]	-6	hSpCas9	negative selection	6729238
31001179	31001202	16	-	27260156	HS294T	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.5437348421285215	[437]	[87,87,145,151]	-7	hSpCas9	negative selection	6729239
31001154	31001177	16	-	27260156	HCC44	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.09568914643878301	[86]	[203,44,119,71]	1	hSpCas9	negative selection	6786233
31001546	31001569	16	-	27260156	HCC44	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.9849533630102143	[307]	[501,543,944,804]	9	hSpCas9	negative selection	6786234
31010385	31010408	16	-	27260156	HCC44	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.22961117610423715	[302]	[382,400,522,318]	3	hSpCas9	negative selection	6786235
31001115	31001138	16	-	27260156	HCC44	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.3744854248989835	[733]	[1077,879,1461,973]	6	hSpCas9	negative selection	6850488
31001579	31001602	16	-	27260156	HCC44	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.4436910881952617	[267]	[224,238,271,161]	-6	hSpCas9	negative selection	6850489
31001179	31001202	16	-	27260156	HCC44	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.16544557453046468	[437]	[595,580,725,350]	2	hSpCas9	negative selection	6850490
31001154	31001177	16	-	27260156	G402	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.2784767416079825	[86]	[68,227,7,202]	3	hSpCas9	negative selection	6907484
31001546	31001569	16	-	27260156	G402	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5478373666018778	[307]	[623,411,754,413]	6	hSpCas9	negative selection	6907485
31010385	31010408	16	-	27260156	G402	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.7640624243603584	[302]	[219,271,153,226]	-7	hSpCas9	negative selection	6907486
31001115	31001138	16	-	27260156	G402	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.11176447400610368	[733]	[1148,748,595,1366]	1	hSpCas9	negative selection	6971739
31001579	31001602	16	-	27260156	G402	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.87768507420701	[267]	[286,91,165,176]	-8	hSpCas9	negative selection	6971740
31001179	31001202	16	-	27260156	G402	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.19212455317561655	[437]	[494,449,838,628]	2	hSpCas9	negative selection	6971741
31001154	31001177	16	-	27260156	L33	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.250645065665279	[86]	[45,28,73,58]	-5	hSpCas9	negative selection	7028735
31001546	31001569	16	-	27260156	L33	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.35158497011635226	[307]	[461,153,179,444]	7	hSpCas9	negative selection	7028736
31010385	31010408	16	-	27260156	L33	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.019042101195539618	[302]	[275,118,155,380]	0	hSpCas9	negative selection	7028737
31001115	31001138	16	-	27260156	L33	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.03941568506465554	[733]	[813,271,435,682]	-1	hSpCas9	negative selection	7092990
31001579	31001602	16	-	27260156	L33	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.09480176682435182	[267]	[330,83,139,242]	-2	hSpCas9	negative selection	7092991
31001179	31001202	16	-	27260156	L33	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.17928537399016103	[437]	[335,188,210,414]	-4	hSpCas9	negative selection	7092992
31001154	31001177	16	-	27260156	K562	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-1.0060409276234115	[86]	[17,42,69,22]	-8	hSpCas9	negative selection	7149986
31001546	31001569	16	-	27260156	K562	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.4371370284293081	[307]	[558,331,342,269]	5	hSpCas9	negative selection	7149987
31010385	31010408	16	-	27260156	K562	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.3451561536537614	[302]	[182,445,205,40]	-4	hSpCas9	negative selection	7149988
31001115	31001138	16	-	27260156	K562	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.22106120577039012	[733]	[882,575,766,802]	2	hSpCas9	negative selection	7214241
31001579	31001602	16	-	27260156	K562	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.44693441230564035	[267]	[240,260,85,124]	-5	hSpCas9	negative selection	7214242
31001179	31001202	16	-	27260156	K562	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.04239250919699918	[437]	[376,661,310,275]	0	hSpCas9	negative selection	7214243
31001154	31001177	16	-	27260156	HT29	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.27747145197674117	[86]	[202,59,167,85]	5	hSpCas9	negative selection	7271237
31001546	31001569	16	-	27260156	HT29	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.38485478945631024	[307]	[607,363,539,443]	7	hSpCas9	negative selection	7271238
31010385	31010408	16	-	27260156	HT29	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.02490818543875628	[302]	[376,349,371,392]	0	hSpCas9	negative selection	7271239
31001115	31001138	16	-	27260156	HT29	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.17217617712612543	[733]	[1034,1208,1072,748]	3	hSpCas9	negative selection	7335492
31001579	31001602	16	-	27260156	HT29	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.3005147616973384	[267]	[341,251,246,224]	-5	hSpCas9	negative selection	7335493
31001179	31001202	16	-	27260156	HT29	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.2643983694942174	[437]	[396,519,556,314]	-5	hSpCas9	negative selection	7335494
31001154	31001177	16	-	27260156	MHHES1	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.0035920669972928643	[86]	[51,76,192,66]	0	hSpCas9	negative selection	7392488
31001546	31001569	16	-	27260156	MHHES1	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.49153804501701637	[307]	[471,753,375,385]	8	hSpCas9	negative selection	7392489
31010385	31010408	16	-	27260156	MHHES1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.3212220151894354	[302]	[321,384,386,553]	6	hSpCas9	negative selection	7392490
31001115	31001138	16	-	27260156	MHHES1	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.10153798438759931	[733]	[791,692,813,761]	-2	hSpCas9	negative selection	7456743
31001579	31001602	16	-	27260156	MHHES1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.6514319539122567	[267]	[217,156,298,109]	-8	hSpCas9	negative selection	7456744
31001179	31001202	16	-	27260156	MHHES1	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.0897485107839883	[437]	[600,599,602,343]	1	hSpCas9	negative selection	7456745
31001154	31001177	16	-	27260156	MEWO	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.41204735162950135	[86]	[143,65,121]	8	hSpCas9	negative selection	7513739
31001546	31001569	16	-	27260156	MEWO	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.48630131680548994	[307]	[484,330,410]	8	hSpCas9	negative selection	7513740
31010385	31010408	16	-	27260156	MEWO	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.12308538015707804	[302]	[328,313,286]	2	hSpCas9	negative selection	7513741
31001115	31001138	16	-	27260156	MEWO	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.14695013175825244	[733]	[961,535,822]	3	hSpCas9	negative selection	7577994
31001579	31001602	16	-	27260156	MEWO	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.26403981713933644	[267]	[230,135,263]	-5	hSpCas9	negative selection	7577995
31001179	31001202	16	-	27260156	MEWO	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.341386810804696	[437]	[555,425,582]	7	hSpCas9	negative selection	7577996
31001154	31001177	16	-	27260156	LNCAPCLONEFGC	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.13883392399140337	[86]	[71,104,77,29]	-2	hSpCas9	negative selection	7634990
31001546	31001569	16	-	27260156	LNCAPCLONEFGC	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5638167610626144	[307]	[303,469,454,424]	8	hSpCas9	negative selection	7634991
31010385	31010408	16	-	27260156	LNCAPCLONEFGC	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.046426429005617886	[302]	[196,298,402,252]	0	hSpCas9	negative selection	7634992
31001115	31001138	16	-	27260156	LNCAPCLONEFGC	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.07001199271543379	[733]	[753,554,719,773]	1	hSpCas9	negative selection	7699245
31001579	31001602	16	-	27260156	LNCAPCLONEFGC	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.3174868831814711	[267]	[152,197,135,283]	-5	hSpCas9	negative selection	7699246
31001179	31001202	16	-	27260156	LNCAPCLONEFGC	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.02575751143418642	[437]	[547,364,360,278]	0	hSpCas9	negative selection	7699247
31001154	31001177	16	-	27260156	PANC0327	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.0925701416556266	[86]	[7,15,95,211]	1	hSpCas9	negative selection	7756241
31001546	31001569	16	-	27260156	PANC0327	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5788988068408047	[307]	[437,324,515,368]	8	hSpCas9	negative selection	7756242
31010385	31010408	16	-	27260156	PANC0327	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.355806509242268	[302]	[414,201,441,342]	5	hSpCas9	negative selection	7756243
31001115	31001138	16	-	27260156	PANC0327	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.09976996186906051	[733]	[609,930,501,713]	1	hSpCas9	negative selection	7820496
31001579	31001602	16	-	27260156	PANC0327	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.4432375455488927	[267]	[102,271,204,101]	-6	hSpCas9	negative selection	7820497
31001179	31001202	16	-	27260156	PANC0327	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.11787197815026207	[437]	[318,302,370,444]	-2	hSpCas9	negative selection	7820498
31001154	31001177	16	-	27260156	NCIH2009	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.1927095099848226	[86]	[143,68,113]	-3	hSpCas9	negative selection	7877492
31001546	31001569	16	-	27260156	NCIH2009	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.44962619538366	[307]	[523,613,610]	6	hSpCas9	negative selection	7877493
31010385	31010408	16	-	27260156	NCIH2009	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.4983051442879891	[302]	[521,538,717]	7	hSpCas9	negative selection	7877494
31001115	31001138	16	-	27260156	NCIH2009	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.17219694111293615	[733]	[1143,1007,1312]	2	hSpCas9	negative selection	7941747
31001579	31001602	16	-	27260156	NCIH2009	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.5688344872595067	[267]	[301,288,174]	-6	hSpCas9	negative selection	7941748
31001179	31001202	16	-	27260156	NCIH2009	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.4203185511453384	[437]	[696,317,405]	-5	hSpCas9	negative selection	7941749
31001154	31001177	16	-	27260156	NCIH1373	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.9669421875391344	[86]	[13,32,90,14]	-7	hSpCas9	negative selection	7998743
31001546	31001569	16	-	27260156	NCIH1373	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	1.0755137853725032	[307]	[1074,504,643,200]	9	hSpCas9	negative selection	7998744
31010385	31010408	16	-	27260156	NCIH1373	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.6525549090072891	[302]	[444,215,94,36]	-6	hSpCas9	negative selection	7998745
31001115	31001138	16	-	27260156	NCIH1373	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.2115601888528137	[733]	[856,835,1234,226]	2	hSpCas9	negative selection	8062998
31001579	31001602	16	-	27260156	NCIH1373	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-2.402264825975981	[267]	[56,9,127,8]	-9	hSpCas9	negative selection	8062999
31001179	31001202	16	-	27260156	NCIH1373	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.37142704995707254	[437]	[201,1420,320,113]	3	hSpCas9	negative selection	8063000
31001154	31001177	16	-	27260156	PATU8902	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-1.023178170880978	[86]	[43,49,97,32]	-7	hSpCas9	negative selection	8119994
31001546	31001569	16	-	27260156	PATU8902	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.3659637202505727	[307]	[851,779,278,337]	4	hSpCas9	negative selection	8119995
31010385	31010408	16	-	27260156	PATU8902	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.0014574686692537	[302]	[818,339,441,2014]	9	hSpCas9	negative selection	8119996
31001115	31001138	16	-	27260156	PATU8902	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.6163022353681813	[733]	[1182,1504,1777,1762]	6	hSpCas9	negative selection	8184249
31001579	31001602	16	-	27260156	PATU8902	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.8826346853962698	[267]	[280,56,165,326]	-7	hSpCas9	negative selection	8184250
31001179	31001202	16	-	27260156	PATU8902	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.18922033150555206	[437]	[845,520,655,769]	2	hSpCas9	negative selection	8184251
31001154	31001177	16	-	27260156	PANC1	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.9381735515207903	[86]	[41,37,48,27]	-8	hSpCas9	negative selection	8241245
31001546	31001569	16	-	27260156	PANC1	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5438496671542327	[307]	[431,439,396,292]	8	hSpCas9	negative selection	8241246
31010385	31010408	16	-	27260156	PANC1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.10194754831420061	[302]	[245,379,323,197]	1	hSpCas9	negative selection	8241247
31001115	31001138	16	-	27260156	PANC1	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.02141700313195205	[733]	[847,688,500,532]	0	hSpCas9	negative selection	8305500
31001579	31001602	16	-	27260156	PANC1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.25303746908455527	[267]	[182,240,193,165]	-4	hSpCas9	negative selection	8305501
31001179	31001202	16	-	27260156	PANC1	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.0074442270630661195	[437]	[285,549,446,277]	0	hSpCas9	negative selection	8305502
31001154	31001177	16	-	27260156	PANC0813	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.9714701344459709	[86]	[145,284,233,134]	9	hSpCas9	negative selection	8362496
31001546	31001569	16	-	27260156	PANC0813	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.8739654280634463	[307]	[642,797,688,526]	9	hSpCas9	negative selection	8362497
31010385	31010408	16	-	27260156	PANC0813	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.9220959424953297	[302]	[868,625,562,656]	9	hSpCas9	negative selection	8362498
31001115	31001138	16	-	27260156	PANC0813	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.09747140587165903	[733]	[869,1103,1083,641]	1	hSpCas9	negative selection	8426751
31001579	31001602	16	-	27260156	PANC0813	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.20084768284098964	[267]	[337,198,235,324]	-3	hSpCas9	negative selection	8426752
31001179	31001202	16	-	27260156	PANC0813	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.20108641835347532	[437]	[716,661,465,533]	3	hSpCas9	negative selection	8426753
31001154	31001177	16	-	27260156	RDES	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.1524827042671797	[86]	[47,179,122,95]	2	hSpCas9	negative selection	8483747
31001546	31001569	16	-	27260156	RDES	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.2490422713684669	[307]	[380,341,382,607]	4	hSpCas9	negative selection	8483748
31010385	31010408	16	-	27260156	RDES	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.07667181011197965	[302]	[184,321,402,457]	-1	hSpCas9	negative selection	8483749
31001115	31001138	16	-	27260156	RDES	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.08749953417429501	[733]	[641,808,1168,1037]	1	hSpCas9	negative selection	8548002
31001579	31001602	16	-	27260156	RDES	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.22577313204352467	[267]	[251,191,302,317]	-4	hSpCas9	negative selection	8548003
31001179	31001202	16	-	27260156	RDES	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.2737489611899601	[437]	[366,381,422,509]	-5	hSpCas9	negative selection	8548004
31001154	31001177	16	-	27260156	PC3	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.1141373990565353	[86]	[70,44,244,74]	2	hSpCas9	negative selection	8604998
31001546	31001569	16	-	27260156	PC3	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.4701303678481714	[307]	[182,361,766,610]	8	hSpCas9	negative selection	8604999
31010385	31010408	16	-	27260156	PC3	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.04540662734467993	[302]	[279,222,359,301]	-1	hSpCas9	negative selection	8605000
31001115	31001138	16	-	27260156	PC3	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.01648001223926865	[733]	[478,754,1250,711]	0	hSpCas9	negative selection	8669253
31001579	31001602	16	-	27260156	PC3	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.10346957226938136	[267]	[141,311,338,419]	2	hSpCas9	negative selection	8669254
31001179	31001202	16	-	27260156	PC3	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.08842594850132751	[437]	[203,392,745,492]	-2	hSpCas9	negative selection	8669255
31001154	31001177	16	-	27260156	PATU8988T	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.49085032384854177	[86]	[61,80,116,216]	7	hSpCas9	negative selection	8726249
31001546	31001569	16	-	27260156	PATU8988T	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.5184887279532062	[307]	[285,454,385,594]	8	hSpCas9	negative selection	8726250
31010385	31010408	16	-	27260156	PATU8988T	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.09816274312447382	[302]	[193,324,358,214]	-2	hSpCas9	negative selection	8726251
31001115	31001138	16	-	27260156	PATU8988T	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.05429921015854844	[733]	[1092,596,722,500]	0	hSpCas9	negative selection	8790504
31001579	31001602	16	-	27260156	PATU8988T	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.07904064535608357	[267]	[211,179,269,317]	-1	hSpCas9	negative selection	8790505
31001179	31001202	16	-	27260156	PATU8988T	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.5776726009114725	[437]	[343,332,202,257]	-7	hSpCas9	negative selection	8790506
31001154	31001177	16	-	27260156	T47D	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.14471960626384428	[86]	[68,38,87,177]	-3	hSpCas9	negative selection	8847500
31001546	31001569	16	-	27260156	T47D	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.6085791457169587	[307]	[504,545,578,557]	9	hSpCas9	negative selection	8847501
31010385	31010408	16	-	27260156	T47D	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.010217138005616078	[302]	[392,272,394,346]	0	hSpCas9	negative selection	8847502
31001115	31001138	16	-	27260156	T47D	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.08844848311351827	[733]	[1038,797,975,829]	1	hSpCas9	negative selection	8911755
31001579	31001602	16	-	27260156	T47D	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.3619530549606439	[267]	[261,212,238,260]	-6	hSpCas9	negative selection	8911756
31001179	31001202	16	-	27260156	T47D	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.11716292514352245	[437]	[494,468,493,421]	-3	hSpCas9	negative selection	8911757
31001154	31001177	16	-	27260156	SU8686	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.07631257402084834	[86]	[50,95,111,111]	1	hSpCas9	negative selection	8968751
31001546	31001569	16	-	27260156	SU8686	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.8352971778657884	[307]	[484,446,553,740]	9	hSpCas9	negative selection	8968752
31010385	31010408	16	-	27260156	SU8686	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.13674025597127537	[302]	[391,306,353,248]	2	hSpCas9	negative selection	8968753
31001115	31001138	16	-	27260156	SU8686	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.2120532221988195	[733]	[674,746,906,1113]	3	hSpCas9	negative selection	9033006
31001579	31001602	16	-	27260156	SU8686	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.06500207566656568	[267]	[174,386,205,232]	-1	hSpCas9	negative selection	9033007
31001179	31001202	16	-	27260156	SU8686	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	0.2237259561560592	[437]	[421,372,692,580]	4	hSpCas9	negative selection	9033008
31001154	31001177	16	-	27260156	SKES1	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	0.07325328370257767	[86]	[173,33,130,35]	1	hSpCas9	negative selection	9090002
31001546	31001569	16	-	27260156	SKES1	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.47681902128457987	[307]	[639,350,385,357]	8	hSpCas9	negative selection	9090003
31010385	31010408	16	-	27260156	SKES1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.050371301735224416	[302]	[287,320,352,213]	-1	hSpCas9	negative selection	9090004
31001115	31001138	16	-	27260156	SKES1	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.011228549848890212	[733]	[623,962,639,690]	0	hSpCas9	negative selection	9154257
31001579	31001602	16	-	27260156	SKES1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.38403761773718526	[267]	[276,226,152,176]	-7	hSpCas9	negative selection	9154258
31001179	31001202	16	-	27260156	SKES1	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.025981399502268104	[437]	[456,516,347,407]	0	hSpCas9	negative selection	9154259
31001154	31001177	16	-	27260156	TOV112D	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.5224243945598483	[86]	[36,31,157,7]	-8	hSpCas9	negative selection	9211253
31001546	31001569	16	-	27260156	TOV112D	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.3584885363392343	[307]	[466,426,410,292]	6	hSpCas9	negative selection	9211254
31010385	31010408	16	-	27260156	TOV112D	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.061394440988777554	[302]	[191,353,258,362]	-1	hSpCas9	negative selection	9211255
31001115	31001138	16	-	27260156	TOV112D	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.036564261059723324	[733]	[841,1121,584,568]	0	hSpCas9	negative selection	9275508
31001579	31001602	16	-	27260156	TOV112D	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.2676500805349361	[267]	[268,358,155,146]	-5	hSpCas9	negative selection	9275509
31001179	31001202	16	-	27260156	TOV112D	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.104508077805894	[437]	[419,407,380,422]	-2	hSpCas9	negative selection	9275510
31001154	31001177	16	-	27260156	TC71	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.22949473495582584	[86]	[106,72,70,65]	-6	hSpCas9	negative selection	9332504
31001546	31001569	16	-	27260156	TC71	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.47316326147824816	[307]	[502,412,449,466]	9	hSpCas9	negative selection	9332505
31010385	31010408	16	-	27260156	TC71	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.27566788779389856	[302]	[400,382,379,409]	6	hSpCas9	negative selection	9332506
31001115	31001138	16	-	27260156	TC71	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	-0.04882531847965821	[733]	[849,639,753,798]	-1	hSpCas9	negative selection	9396759
31001579	31001602	16	-	27260156	TC71	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.11897538741031077	[267]	[237,271,214,339]	-3	hSpCas9	negative selection	9396760
31001179	31001202	16	-	27260156	TC71	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.0769312469760007	[437]	[414,518,338,515]	-2	hSpCas9	negative selection	9396761
31001154	31001177	16	-	27260156	TC32	viability	CTGCATTGAGAAACTGTCGGAGG	STX1B	ENSG00000099365	-0.32530747047671893	[86]	[39,65,118,42]	-5	hSpCas9	negative selection	9453755
31001546	31001569	16	-	27260156	TC32	viability	CGTGGATCGGGACCACTTCATGG	STX1B	ENSG00000099365	0.36647083250560575	[307]	[363,219,567,414]	6	hSpCas9	negative selection	9453756
31010385	31010408	16	-	27260156	TC32	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.3179505028626526	[302]	[280,86,304,291]	-5	hSpCas9	negative selection	9453757
31001115	31001138	16	-	27260156	TC32	viability	AAAACAGCATAGCGCCATCCTGG	STX1B	ENSG00000099365	0.22166611957278626	[733]	[648,637,1246,794]	4	hSpCas9	negative selection	9518010
31001579	31001602	16	-	27260156	TC32	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.10969136398280943	[267]	[205,268,273,333]	2	hSpCas9	negative selection	9518011
31001179	31001202	16	-	27260156	TC32	viability	TGCTCCAGGTGGAAGAGATCCGG	STX1B	ENSG00000099365	-0.0633810986836588	[437]	[398,268,501,450]	-1	hSpCas9	negative selection	9518012
30993207	30993230	16	-	27869803	HPAFII	viability after 27 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.4662980400504647	[389]	[201,350,NaN]	4	hSpCas9	negative selection	9556850
30993454	30993477	16	-	27869803	HPAFII	viability after 27 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.7593613456326893	[352]	[149,75,NaN]	-5	hSpCas9	negative selection	9556851
30996727	30996750	16	-	27869803	HPAFII	viability after 27 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.4281476820040434	[264]	[90,113,NaN]	-3	hSpCas9	negative selection	9556852
30996973	30996996	16	-	27869803	HPAFII	viability after 27 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.38314840825033486	[342]	[322,161,NaN]	3	hSpCas9	negative selection	9556853
30997549	30997572	16	-	27869803	HPAFII	viability after 27 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.3602468528393217	[476]	[196,193,NaN]	-3	hSpCas9	negative selection	9556854
31001549	31001572	16	+	27869803	HPAFII	viability after 27 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.7510827990099049	[269]	[215,257,NaN]	6	hSpCas9	negative selection	9556855
30993207	30993230	16	-	27869803	HPAFII	viability after 15 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.3241162771274455	[389]	[623,462,NaN]	4	hSpCas9	negative selection	9639299
30993454	30993477	16	-	27869803	HPAFII	viability after 15 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.6904828569988611	[352]	[387,139,NaN]	-6	hSpCas9	negative selection	9639300
30996727	30996750	16	-	27869803	HPAFII	viability after 15 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.14129206252176113	[264]	[256,258,NaN]	-2	hSpCas9	negative selection	9639301
30996973	30996996	16	-	27869803	HPAFII	viability after 15 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.17495813918713893	[342]	[528,345,NaN]	2	hSpCas9	negative selection	9639302
30997549	30997572	16	-	27869803	HPAFII	viability after 15 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.560224584525582	[476]	[433,293,NaN]	-6	hSpCas9	negative selection	9639303
31001549	31001572	16	+	27869803	HPAFII	viability after 15 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.6847248156193664	[269]	[598,383,NaN]	7	hSpCas9	negative selection	9639304
30993207	30993230	16	-	27869803	ASPC1	viability after 36 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.9010250084254241	[980]	[598,1140,262]	8	hSpCas9	negative selection	9721748
30993454	30993477	16	-	27869803	ASPC1	viability after 36 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.42919590031389737	[737]	[329,111,154]	-4	hSpCas9	negative selection	9721749
30996727	30996750	16	-	27869803	ASPC1	viability after 36 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.5827472025973739	[717]	[441,539,193]	6	hSpCas9	negative selection	9721750
30996973	30996996	16	-	27869803	ASPC1	viability after 36 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.5001053557013213	[862]	[274,553,425]	5	hSpCas9	negative selection	9721751
30997549	30997572	16	-	27869803	ASPC1	viability after 36 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.6369932856616358	[1100]	[912,549,407]	6	hSpCas9	negative selection	9721752
31001549	31001572	16	+	27869803	ASPC1	viability after 36 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.9482757463217704	[811]	[830,377,475]	8	hSpCas9	negative selection	9721753
30993207	30993230	16	-	27869803	PATU8988S	viability after 35 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.34934932817489817	[883]	[262,295,NaN]	-4	hSpCas9	negative selection	9804197
30993454	30993477	16	-	27869803	PATU8988S	viability after 35 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.22716496044290638	[698]	[243,236,NaN]	-2	hSpCas9	negative selection	9804198
30996727	30996750	16	-	27869803	PATU8988S	viability after 35 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.6648644087753991	[544]	[346,348,NaN]	7	hSpCas9	negative selection	9804199
30996973	30996996	16	-	27869803	PATU8988S	viability after 35 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-1.1794765918535868	[831]	[123,171,NaN]	-8	hSpCas9	negative selection	9804200
30997549	30997572	16	-	27869803	PATU8988S	viability after 35 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.11837900041385496	[957]	[562,273,NaN]	1	hSpCas9	negative selection	9804201
31001549	31001572	16	+	27869803	PATU8988S	viability after 35 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.7154278486259519	[574]	[157,123,NaN]	-6	hSpCas9	negative selection	9804202
30993207	30993230	16	-	27869803	PATU8988S	viability after 31 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.5274035625637696	[883]	[233,257,NaN]	-5	hSpCas9	negative selection	9886646
30993454	30993477	16	-	27869803	PATU8988S	viability after 31 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.21200643450326878	[698]	[193,299,NaN]	-2	hSpCas9	negative selection	9886647
30996727	30996750	16	-	27869803	PATU8988S	viability after 31 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	0.24647845287859854	[544]	[270,240,NaN]	3	hSpCas9	negative selection	9886648
30996973	30996996	16	-	27869803	PATU8988S	viability after 31 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	-0.7575778853452162	[831]	[142,263,NaN]	-7	hSpCas9	negative selection	9886649
30997549	30997572	16	-	27869803	PATU8988S	viability after 31 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.012854129268375591	[957]	[457,292,NaN]	0	hSpCas9	negative selection	9886650
31001549	31001572	16	+	27869803	PATU8988S	viability after 31 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	-0.25576696844805724	[574]	[140,256,NaN]	-3	hSpCas9	negative selection	9886651
30993207	30993230	16	-	27869803	HPAFII	viability after 35 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.36456499977723344	[389]	[177,339,NaN]	2	hSpCas9	negative selection	9969095
30993454	30993477	16	-	27869803	HPAFII	viability after 35 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.5168381126457481	[352]	[154,90,NaN]	-3	hSpCas9	negative selection	9969096
30996727	30996750	16	-	27869803	HPAFII	viability after 35 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.17299015286563865	[264]	[110,127,NaN]	-1	hSpCas9	negative selection	9969097
30996973	30996996	16	-	27869803	HPAFII	viability after 35 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.693232008912207	[342]	[276,284,NaN]	4	hSpCas9	negative selection	9969098
30997549	30997572	16	-	27869803	HPAFII	viability after 35 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	0.2994451401211323	[476]	[188,418,NaN]	2	hSpCas9	negative selection	9969099
31001549	31001572	16	+	27869803	HPAFII	viability after 35 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.4318997674852659	[269]	[142,230,NaN]	2	hSpCas9	negative selection	9969100
30993207	30993230	16	-	27869803	HPAFII	viability after 31 days	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.775743056801755	[389]	[189,575,NaN]	5	hSpCas9	negative selection	10051544
30993454	30993477	16	-	27869803	HPAFII	viability after 31 days	GGACTCACAGATGACGAAGCAGG	STX1B	ENSG00000099365	-0.8856076156539132	[352]	[156,52,NaN]	-5	hSpCas9	negative selection	10051545
30996727	30996750	16	-	27869803	HPAFII	viability after 31 days	GACCACCACCAACGAAGAACTGG	STX1B	ENSG00000099365	-0.2656090571061827	[264]	[94,154,NaN]	-2	hSpCas9	negative selection	10051546
30996973	30996996	16	-	27869803	HPAFII	viability after 31 days	ACCGGGACCGCTGCAAGGACCGG	STX1B	ENSG00000099365	0.460532662209662	[342]	[306,218,NaN]	3	hSpCas9	negative selection	10051547
30997549	30997572	16	-	27869803	HPAFII	viability after 31 days	CGAGCAAAGCATTGAACAGGAGG	STX1B	ENSG00000099365	-0.10261118226135302	[476]	[155,350,NaN]	0	hSpCas9	negative selection	10051548
31001549	31001572	16	+	27869803	HPAFII	viability after 31 days	TGAAGTGGTCCCGATCCACGTGG	STX1B	ENSG00000099365	0.36726410036368595	[269]	[160,232,NaN]	2	hSpCas9	negative selection	10051549
30996964	30996987	16	-	28162770	P31FUJ	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.38436132338573287	[360]	[324]	-3	hSpCas9	negative selection	10244993
30997501	30997524	16	+	28162770	P31FUJ	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	1.1216285301603133	[78]	[201]	9	hSpCas9	negative selection	10244994
30997546	30997569	16	-	28162770	P31FUJ	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.0853737556118761	[76]	[95]	0	hSpCas9	negative selection	10244995
30997029	30997052	16	-	28162770	P31FUJ	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	1.8874920293033333	[22]	[99]	9	hSpCas9	negative selection	10244996
30993130	30993153	16	-	28162770	P31FUJ	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.7218058927716071	[112]	[218]	8	hSpCas9	negative selection	10244997
31001579	31001602	16	-	28162770	P31FUJ	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.03382116968798343	[141]	[162]	0	hSpCas9	negative selection	10244998
31000982	31001005	16	-	28162770	P31FUJ	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.1736543183658984	[453]	[472]	-2	hSpCas9	negative selection	10244999
30993207	30993230	16	-	28162770	P31FUJ	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.4290929565416416	[212]	[336]	5	hSpCas9	negative selection	10245000
31010385	31010408	16	-	28162770	P31FUJ	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.0457332949596032	[53]	[130]	9	hSpCas9	negative selection	10245001
31010370	31010393	16	-	28162770	P31FUJ	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.040916797430363805	[425]	[514]	0	hSpCas9	negative selection	10245002
30996964	30996987	16	-	28162770	TF1	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10414359
30997501	30997524	16	+	28162770	TF1	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10414360
30997546	30997569	16	-	28162770	TF1	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10414361
30997029	30997052	16	-	28162770	TF1	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10414362
30993130	30993153	16	-	28162770	TF1	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10414363
31001579	31001602	16	-	28162770	TF1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	NaN	[NaN]	[223]	1	hSpCas9	negative selection	10414364
31000982	31001005	16	-	28162770	TF1	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	NaN	[NaN]	[403]	1	hSpCas9	negative selection	10414365
30993207	30993230	16	-	28162770	TF1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10414366
31010385	31010408	16	-	28162770	TF1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10414367
31010370	31010393	16	-	28162770	TF1	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	NaN	[NaN]	[428]	1	hSpCas9	negative selection	10414368
30996964	30996987	16	-	28162770	SKM1	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.2005133212757354	[103]	[159]	-2	hSpCas9	negative selection	10583725
30997501	30997524	16	+	28162770	SKM1	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	1.2748598412305834	[17]	[76]	9	hSpCas9	negative selection	10583726
30997546	30997569	16	-	28162770	SKM1	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.9406461945206246	[37]	[34]	-6	hSpCas9	negative selection	10583727
30997029	30997052	16	-	28162770	SKM1	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-4.406964198743161	[11]	[0]	-9	hSpCas9	negative selection	10583728
30993130	30993153	16	-	28162770	SKM1	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.03713576613814479	[42]	[77]	0	hSpCas9	negative selection	10583729
31001579	31001602	16	-	28162770	SKM1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.01336760020519523	[50]	[90]	0	hSpCas9	negative selection	10583730
31000982	31001005	16	-	28162770	SKM1	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	0.24476731419069542	[94]	[198]	2	hSpCas9	negative selection	10583731
30993207	30993230	16	-	28162770	SKM1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.4003907233144424	[32]	[76]	4	hSpCas9	negative selection	10583732
31010385	31010408	16	-	28162770	SKM1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.9094645392723446	[16]	[15]	-6	hSpCas9	negative selection	10583733
31010370	31010393	16	-	28162770	SKM1	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.1637844427582935	[101]	[201]	1	hSpCas9	negative selection	10583734
30996964	30996987	16	-	28162770	SKM1	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.2005133212757354	[103]	[159]	-2	hSpCas9	negative selection	10753091
30997501	30997524	16	+	28162770	SKM1	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	1.2748598412305834	[17]	[76]	9	hSpCas9	negative selection	10753092
30997546	30997569	16	-	28162770	SKM1	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.9406461945206246	[37]	[34]	-6	hSpCas9	negative selection	10753093
30997029	30997052	16	-	28162770	SKM1	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-4.406964198743161	[11]	[0]	-9	hSpCas9	negative selection	10753094
30993130	30993153	16	-	28162770	SKM1	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.03713576613814479	[42]	[77]	0	hSpCas9	negative selection	10753095
31001579	31001602	16	-	28162770	SKM1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.01336760020519523	[50]	[90]	0	hSpCas9	negative selection	10753096
31000982	31001005	16	-	28162770	SKM1	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	0.24476731419069542	[94]	[198]	2	hSpCas9	negative selection	10753097
30993207	30993230	16	-	28162770	SKM1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.4003907233144424	[32]	[76]	4	hSpCas9	negative selection	10753098
31010385	31010408	16	-	28162770	SKM1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.9094645392723446	[16]	[15]	-6	hSpCas9	negative selection	10753099
31010370	31010393	16	-	28162770	SKM1	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.1637844427582935	[101]	[201]	1	hSpCas9	negative selection	10753100
30996964	30996987	16	-	28162770	PL21	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-1.087662696493416	[375]	[76]	-6	hSpCas9	negative selection	10922457
30997501	30997524	16	+	28162770	PL21	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.434604868126343	[67]	[39]	4	hSpCas9	negative selection	10922458
30997546	30997569	16	-	28162770	PL21	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.0343256391477027	[79]	[33]	0	hSpCas9	negative selection	10922459
30997029	30997052	16	-	28162770	PL21	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.8309058048236011	[30]	[23]	7	hSpCas9	negative selection	10922460
30993130	30993153	16	-	28162770	PL21	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	-0.6028235384511262	[163]	[46]	-4	hSpCas9	negative selection	10922461
31001579	31001602	16	-	28162770	PL21	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.2193992770244645	[213]	[79]	-1	hSpCas9	negative selection	10922462
31000982	31001005	16	-	28162770	PL21	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.0948671810827535	[291]	[118]	0	hSpCas9	negative selection	10922463
30993207	30993230	16	-	28162770	PL21	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	1.1261390330455434	[159]	[151]	8	hSpCas9	negative selection	10922464
31010385	31010408	16	-	28162770	PL21	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.9590589803599336	[66]	[14]	-6	hSpCas9	negative selection	10922465
31010370	31010393	16	-	28162770	PL21	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.46487230779513944	[282]	[169]	4	hSpCas9	negative selection	10922466
30996964	30996987	16	-	28162770	P31FUJ	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.38436132338573287	[360]	[324]	-3	hSpCas9	negative selection	11091823
30997501	30997524	16	+	28162770	P31FUJ	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	1.1216285301603133	[78]	[201]	9	hSpCas9	negative selection	11091824
30997546	30997569	16	-	28162770	P31FUJ	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.0853737556118761	[76]	[95]	0	hSpCas9	negative selection	11091825
30997029	30997052	16	-	28162770	P31FUJ	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	1.8874920293033333	[22]	[99]	9	hSpCas9	negative selection	11091826
30993130	30993153	16	-	28162770	P31FUJ	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.7218058927716071	[112]	[218]	8	hSpCas9	negative selection	11091827
31001579	31001602	16	-	28162770	P31FUJ	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.03382116968798343	[141]	[162]	0	hSpCas9	negative selection	11091828
31000982	31001005	16	-	28162770	P31FUJ	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.1736543183658984	[453]	[472]	-2	hSpCas9	negative selection	11091829
30993207	30993230	16	-	28162770	P31FUJ	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.4290929565416416	[212]	[336]	5	hSpCas9	negative selection	11091830
31010385	31010408	16	-	28162770	P31FUJ	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	1.0457332949596032	[53]	[130]	9	hSpCas9	negative selection	11091831
31010370	31010393	16	-	28162770	P31FUJ	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.040916797430363805	[425]	[514]	0	hSpCas9	negative selection	11091832
30996964	30996987	16	-	28162770	OCIAML5	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-1.084727327654272	[234]	[199]	-6	hSpCas9	negative selection	11261189
30997501	30997524	16	+	28162770	OCIAML5	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.08169973073591619	[77]	[148]	0	hSpCas9	negative selection	11261190
30997546	30997569	16	-	28162770	OCIAML5	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.43702907158515336	[62]	[83]	-3	hSpCas9	negative selection	11261191
30997029	30997052	16	-	28162770	OCIAML5	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-1.6676419997265695	[43]	[24]	-7	hSpCas9	negative selection	11261192
30993130	30993153	16	-	28162770	OCIAML5	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.38672028872311964	[99]	[235]	3	hSpCas9	negative selection	11261193
31001579	31001602	16	-	28162770	OCIAML5	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.0008923183670291879	[128]	[232]	0	hSpCas9	negative selection	11261194
31000982	31001005	16	-	28162770	OCIAML5	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	0.2556212984503766	[199]	[430]	2	hSpCas9	negative selection	11261195
30993207	30993230	16	-	28162770	OCIAML5	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.7287442865866917	[115]	[346]	6	hSpCas9	negative selection	11261196
31010385	31010408	16	-	28162770	OCIAML5	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.4597491480852368	[63]	[83]	-3	hSpCas9	negative selection	11261197
31010370	31010393	16	-	28162770	OCIAML5	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.23539627038634248	[199]	[424]	2	hSpCas9	negative selection	11261198
30996964	30996987	16	-	28162770	EOL1	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.4935956385761311	[774]	[289]	-4	hSpCas9	negative selection	11430555
30997501	30997524	16	+	28162770	EOL1	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.46264366725371664	[72]	[52]	4	hSpCas9	negative selection	11430556
30997546	30997569	16	-	28162770	EOL1	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.5190330464101973	[150]	[113]	5	hSpCas9	negative selection	11430557
30997029	30997052	16	-	28162770	EOL1	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.9749253524755008	[96]	[25]	-6	hSpCas9	negative selection	11430558
30993130	30993153	16	-	28162770	EOL1	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	-0.02400546301078939	[302]	[156]	0	hSpCas9	negative selection	11430559
31001579	31001602	16	-	28162770	EOL1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.30448146989346236	[311]	[202]	2	hSpCas9	negative selection	11430560
31000982	31001005	16	-	28162770	EOL1	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	1.3173324640022506	[440]	[578]	9	hSpCas9	negative selection	11430561
30993207	30993230	16	-	28162770	EOL1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.06791194674171186	[200]	[110]	0	hSpCas9	negative selection	11430562
31010385	31010408	16	-	28162770	EOL1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-1.145841556320863	[62]	[14]	-6	hSpCas9	negative selection	11430563
31010370	31010393	16	-	28162770	EOL1	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.37026488893880505	[441]	[300]	3	hSpCas9	negative selection	11430564
30996964	30996987	16	-	28162770	MOLM13	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.2806875029919159	[498]	[296]	-2	hSpCas9	negative selection	11599921
30997501	30997524	16	+	28162770	MOLM13	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	-0.08280321709183136	[103]	[70]	0	hSpCas9	negative selection	11599922
30997546	30997569	16	-	28162770	MOLM13	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.9653890410153955	[84]	[119]	7	hSpCas9	negative selection	11599923
30997029	30997052	16	-	28162770	MOLM13	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-1.1170731191765775	[47]	[15]	-5	hSpCas9	negative selection	11599924
30993130	30993153	16	-	28162770	MOLM13	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.07596912189038835	[226]	[172]	0	hSpCas9	negative selection	11599925
31001579	31001602	16	-	28162770	MOLM13	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.9032264424339533	[246]	[333]	7	hSpCas9	negative selection	11599926
31000982	31001005	16	-	28162770	MOLM13	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.22557457398504077	[489]	[302]	-1	hSpCas9	negative selection	11599927
30993207	30993230	16	-	28162770	MOLM13	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.26724885957062067	[262]	[157]	-2	hSpCas9	negative selection	11599928
31010385	31010408	16	-	28162770	MOLM13	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.6264380010035744	[78]	[36]	-4	hSpCas9	negative selection	11599929
31010370	31010393	16	-	28162770	MOLM13	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.2070152444893757	[454]	[284]	-1	hSpCas9	negative selection	11599930
30996964	30996987	16	-	28162770	HEL	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.5085391068474256	[441]	[198]	-3	hSpCas9	negative selection	11769287
30997501	30997524	16	+	28162770	HEL	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.8406782096122657	[67]	[77]	7	hSpCas9	negative selection	11769288
30997546	30997569	16	-	28162770	HEL	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.7496540359168689	[129]	[139]	6	hSpCas9	negative selection	11769289
30997029	30997052	16	-	28162770	HEL	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-1.7442842911088903	[67]	[12]	-7	hSpCas9	negative selection	11769290
30993130	30993153	16	-	28162770	HEL	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	1.0347210950515353	[204]	[268]	8	hSpCas9	negative selection	11769291
31001579	31001602	16	-	28162770	HEL	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	0.5974740982645749	[258]	[250]	5	hSpCas9	negative selection	11769292
31000982	31001005	16	-	28162770	HEL	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.8657716082829261	[440]	[154]	-5	hSpCas9	negative selection	11769293
30993207	30993230	16	-	28162770	HEL	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.18886363630392453	[209]	[117]	-1	hSpCas9	negative selection	11769294
31010385	31010408	16	-	28162770	HEL	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.4568722866890228	[90]	[79]	4	hSpCas9	negative selection	11769295
31010370	31010393	16	-	28162770	HEL	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.7775929669480001	[454]	[169]	-5	hSpCas9	negative selection	11769296
30996964	30996987	16	-	28162770	MV411	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.8475755640774452	[454]	[212]	-5	hSpCas9	negative selection	11938653
30997501	30997524	16	+	28162770	MV411	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	1.2791464105101134	[44]	[91]	9	hSpCas9	negative selection	11938654
30997546	30997569	16	-	28162770	MV411	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.8995142473624684	[83]	[131]	7	hSpCas9	negative selection	11938655
30997029	30997052	16	-	28162770	MV411	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	0.5104719566165692	[59]	[71]	4	hSpCas9	negative selection	11938656
30993130	30993153	16	-	28162770	MV411	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.11815453383780881	[174]	[159]	1	hSpCas9	negative selection	11938657
31001579	31001602	16	-	28162770	MV411	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.3306385643531411	[208]	[139]	-2	hSpCas9	negative selection	11938658
31000982	31001005	16	-	28162770	MV411	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.5813487518063397	[372]	[209]	-4	hSpCas9	negative selection	11938659
30993207	30993230	16	-	28162770	MV411	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-1.1083241391804624	[150]	[58]	-6	hSpCas9	negative selection	11938660
31010385	31010408	16	-	28162770	MV411	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	2.8181861922842306	[33]	[201]	9	hSpCas9	negative selection	11938661
31010370	31010393	16	-	28162770	MV411	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	0.11334465519549242	[337]	[307]	1	hSpCas9	negative selection	11938662
30996964	30996987	16	-	28162770	MONOMAC1	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	0.4987060843801395	[212]	[344]	5	hSpCas9	negative selection	12108019
30997501	30997524	16	+	28162770	MONOMAC1	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.7590198053528494	[49]	[96]	7	hSpCas9	negative selection	12108020
30997546	30997569	16	-	28162770	MONOMAC1	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.03265002915867132	[57]	[64]	0	hSpCas9	negative selection	12108021
30997029	30997052	16	-	28162770	MONOMAC1	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.3490399405046034	[19]	[17]	-3	hSpCas9	negative selection	12108022
30993130	30993153	16	-	28162770	MONOMAC1	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.5308836075036454	[95]	[158]	5	hSpCas9	negative selection	12108023
31001579	31001602	16	-	28162770	MONOMAC1	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.0874123558850555	[113]	[122]	-1	hSpCas9	negative selection	12108024
31000982	31001005	16	-	28162770	MONOMAC1	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.5585449499216022	[193]	[150]	-5	hSpCas9	negative selection	12108025
30993207	30993230	16	-	28162770	MONOMAC1	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.5656344612991275	[88]	[150]	5	hSpCas9	negative selection	12108026
31010385	31010408	16	-	28162770	MONOMAC1	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-0.19703684705955404	[32]	[32]	-2	hSpCas9	negative selection	12108027
31010370	31010393	16	-	28162770	MONOMAC1	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.4858343489584293	[225]	[184]	-4	hSpCas9	negative selection	12108028
30996964	30996987	16	-	28162770	OCIAML2	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.8665585015733003	[74]	[227]	-6	hSpCas9	negative selection	12277385
30997501	30997524	16	+	28162770	OCIAML2	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	-0.7264687296717511	[19]	[66]	-5	hSpCas9	negative selection	12277386
30997546	30997569	16	-	28162770	OCIAML2	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	0.43118978081893533	[18]	[141]	4	hSpCas9	negative selection	12277387
30997029	30997052	16	-	28162770	OCIAML2	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-0.7336642310759549	[8]	[29]	-5	hSpCas9	negative selection	12277388
30993130	30993153	16	-	28162770	OCIAML2	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	-0.2893000605275995	[27]	[126]	-2	hSpCas9	negative selection	12277389
31001579	31001602	16	-	28162770	OCIAML2	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-0.026529860360854807	[42]	[233]	0	hSpCas9	negative selection	12277390
31000982	31001005	16	-	28162770	OCIAML2	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.23796906845188615	[59]	[281]	-2	hSpCas9	negative selection	12277391
30993207	30993230	16	-	28162770	OCIAML2	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	0.7728242116221165	[16]	[160]	7	hSpCas9	negative selection	12277392
31010385	31010408	16	-	28162770	OCIAML2	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	0.36587144247495895	[6]	[49]	3	hSpCas9	negative selection	12277393
31010370	31010393	16	-	28162770	OCIAML2	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.6100328819075774	[75]	[275]	-4	hSpCas9	negative selection	12277394
30996964	30996987	16	-	28162770	OCIAML3	viability	GCTGCAAGGACCGGATCCAGCGG	STX1B	ENSG00000099365	-0.16699749937924346	[89]	[241]	-1	hSpCas9	negative selection	12446751
30997501	30997524	16	+	28162770	OCIAML3	viability	CCTGGGTCTTGCGGATGCGCAGG	STX1B	ENSG00000099365	0.02070220379104515	[15]	[48]	0	hSpCas9	negative selection	12446752
30997546	30997569	16	-	28162770	OCIAML3	viability	GCAAAGCATTGAACAGGAGGAGG	STX1B	ENSG00000099365	-0.3798828349713159	[24]	[57]	-3	hSpCas9	negative selection	12446753
30997029	30997052	16	-	28162770	OCIAML3	viability	ACTGTCCCGGAAGTTCGTGGAGG	STX1B	ENSG00000099365	-1.915935735211526	[9]	[7]	-8	hSpCas9	negative selection	12446754
30993130	30993153	16	-	28162770	OCIAML3	viability	AATATCAGAGCAAGGCCCGGAGG	STX1B	ENSG00000099365	0.7614730142742258	[33]	[173]	6	hSpCas9	negative selection	12446755
31001579	31001602	16	-	28162770	OCIAML3	viability	GAAAGACAGTGATGATGAAGAGG	STX1B	ENSG00000099365	-1.0746334812305838	[59]	[85]	-6	hSpCas9	negative selection	12446756
31000982	31001005	16	-	28162770	OCIAML3	viability	AGAGACCAAACAGGAGCTGGAGG	STX1B	ENSG00000099365	-0.612866667575479	[76]	[151]	-5	hSpCas9	negative selection	12446757
30993207	30993230	16	-	28162770	OCIAML3	viability	TGACCGCATCGAGTACAACGTGG	STX1B	ENSG00000099365	-0.3946988321007564	[26]	[61]	-3	hSpCas9	negative selection	12446758
31010385	31010408	16	-	28162770	OCIAML3	viability	GCCGTCGCAGGATGAAGGATCGG	STX1B	ENSG00000099365	-1.972519263577893	[12]	[9]	-8	hSpCas9	negative selection	12446759
31010370	31010393	16	-	28162770	OCIAML3	viability	AGGATCGGACTCAAGAGCTGCGG	STX1B	ENSG00000099365	-0.22528533395785977	[90]	[234]	-2	hSpCas9	negative selection	12446760