Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6812
• Symbol: STXBP1
• Description: syntaxin binding protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/STXBP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
127668158	127668181	9	+	26472758	Jiyoye	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.07956358312715917	[219]	[156]	0	hSpCas9	negative selection	158583
127658409	127658432	9	-	26472758	Jiyoye	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	-1.3033180012991419	[35]	[10]	-7	hSpCas9	negative selection	158584
127653766	127653789	9	+	26472758	Jiyoye	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.02345897282398901	[216]	[160]	0	hSpCas9	negative selection	158585
127668083	127668106	9	+	26472758	Jiyoye	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	1.354707961611738	[27]	[53]	7	hSpCas9	negative selection	158586
127676633	127676656	9	+	26472758	Jiyoye	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	4.992137882227029	[0]	[23]	9	hSpCas9	negative selection	158587
127678483	127678506	9	+	26472758	Jiyoye	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.30903165249353526	[45]	[27]	-2	hSpCas9	negative selection	158588
127678511	127678534	9	+	26472758	Jiyoye	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.26967185775593844	[131]	[119]	2	hSpCas9	negative selection	158589
127680212	127680235	9	-	26472758	Jiyoye	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	2.1296414059769644	[9]	[32]	9	hSpCas9	negative selection	158590
127682437	127682460	9	+	26472758	Jiyoye	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-1.7348436233665545	[127]	[28]	-8	hSpCas9	negative selection	158591
127682463	127682486	9	-	26472758	Jiyoye	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-1.3495534674817626	[97]	[28]	-7	hSpCas9	negative selection	158592
127668158	127668181	9	+	26472758	KBM7	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.008681829507667382	[1247,1092]	[526,562]	0	hSpCas9	negative selection	349701
127658409	127658432	9	-	26472758	KBM7	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.7008523961926714	[58,74]	[59,44]	7	hSpCas9	negative selection	349702
127653766	127653789	9	+	26472758	KBM7	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.2420824886333477	[782,501]	[213,283]	-2	hSpCas9	negative selection	349703
127668083	127668106	9	+	26472758	KBM7	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.9220977180272754	[214,246]	[240,178]	8	hSpCas9	negative selection	349704
127676633	127676656	9	+	26472758	KBM7	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.6921467519569873	[76,92]	[121,14]	7	hSpCas9	negative selection	349705
127678483	127678506	9	+	26472758	KBM7	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.9466542475392676	[273,79]	[50,31]	-6	hSpCas9	negative selection	349706
127678511	127678534	9	+	26472758	KBM7	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.08732658674667126	[1147,1084]	[665,462]	0	hSpCas9	negative selection	349707
127680212	127680235	9	-	26472758	KBM7	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.3329645650841413	[725,623]	[94,152]	-7	hSpCas9	negative selection	349708
127682437	127682460	9	+	26472758	KBM7	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.13431828658218947	[359,270]	[126,139]	-1	hSpCas9	negative selection	349709
127682463	127682486	9	-	26472758	KBM7	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.29565078824900604	[167,150]	[40,78]	-3	hSpCas9	negative selection	349710
127668158	127668181	9	+	26472758	Raji	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.10910828452316423	[487]	[104]	-1	hSpCas9	negative selection	540819
127658409	127658432	9	-	26472758	Raji	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	-2.255186544011109	[143]	[6]	-9	hSpCas9	negative selection	540820
127653766	127653789	9	+	26472758	Raji	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	1.0755346693342598	[228]	[111]	8	hSpCas9	negative selection	540821
127668083	127668106	9	+	26472758	Raji	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.5040425053375888	[78]	[25]	5	hSpCas9	negative selection	540822
127676633	127676656	9	+	26472758	Raji	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.13337874390654414	[54]	[13]	1	hSpCas9	negative selection	540823
127678483	127678506	9	+	26472758	Raji	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	1.3000286133159955	[34]	[19]	9	hSpCas9	negative selection	540824
127678511	127678534	9	+	26472758	Raji	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.08041648777333021	[431]	[105]	0	hSpCas9	negative selection	540825
127680212	127680235	9	-	26472758	Raji	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-2.4775789653475564	[263]	[10]	-9	hSpCas9	negative selection	540826
127682437	127682460	9	+	26472758	Raji	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.228551417507642	[206]	[40]	-2	hSpCas9	negative selection	540827
127682463	127682486	9	-	26472758	Raji	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.2676558959733253	[82]	[15]	-2	hSpCas9	negative selection	540828
127668158	127668181	9	+	26472758	K562	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.34490105525814585	[828]	[550]	-2	hSpCas9	negative selection	731937
127658409	127658432	9	-	26472758	K562	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.04587304828436656	[69]	[60]	0	hSpCas9	negative selection	731938
127653766	127653789	9	+	26472758	K562	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.44363726601881287	[405]	[251]	-3	hSpCas9	negative selection	731939
127668083	127668106	9	+	26472758	K562	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.9142701259741159	[153]	[244]	7	hSpCas9	negative selection	731940
127676633	127676656	9	+	26472758	K562	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.880262397389787	[64]	[100]	7	hSpCas9	negative selection	731941
127678483	127678506	9	+	26472758	K562	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-1.8999711816687284	[83]	[18]	-7	hSpCas9	negative selection	731942
127678511	127678534	9	+	26472758	K562	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.07498104088537638	[739]	[657]	0	hSpCas9	negative selection	731943
127680212	127680235	9	-	26472758	K562	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-3.296149653696256	[511]	[43]	-8	hSpCas9	negative selection	731944
127682437	127682460	9	+	26472758	K562	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.1250666197979896	[238]	[184]	-1	hSpCas9	negative selection	731945
127682463	127682486	9	-	26472758	K562	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	0.3028354138917688	[120]	[125]	2	hSpCas9	negative selection	731946
127658440	127658463	9	-	26627737	DLD1	viability	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	1.598519717175785	[14]	[18,6,15]	9	hSpCas9	negative selection	841337
127660080	127660103	9	-	26627737	DLD1	viability	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.706038970062759	[517]	[196,208,367]	7	hSpCas9	negative selection	841338
127663309	127663332	9	-	26627737	DLD1	viability	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	-0.17737042106854817	[740]	[191,176,238]	-2	hSpCas9	negative selection	841339
127665264	127665287	9	-	26627737	DLD1	viability	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	-0.7560008761166979	[581]	[75,171,81]	-6	hSpCas9	negative selection	841340
127666186	127666209	9	-	26627737	DLD1	viability	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-0.29643562497617126	[162]	[64,37,23]	-3	hSpCas9	negative selection	841341
127668143	127668166	9	-	26627737	DLD1	viability	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.7229651442578613	[180]	[149,65,66]	7	hSpCas9	negative selection	841342
127658440	127658463	9	-	26627737	GBM cells	viability after 5 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.188548966364654	[33]	[18,12]	-3	hSpCas9	negative selection	923652
127660080	127660103	9	-	26627737	GBM cells	viability after 5 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.5966443057687915	[245]	[187,210]	8	hSpCas9	negative selection	923653
127663309	127663332	9	-	26627737	GBM cells	viability after 5 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.3886617686808729	[380]	[234,299]	6	hSpCas9	negative selection	923654
127665264	127665287	9	-	26627737	GBM cells	viability after 5 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.6340861872288411	[160]	[120,146]	8	hSpCas9	negative selection	923655
127666186	127666209	9	-	26627737	GBM cells	viability after 5 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.9891116838572638	[123]	[133,129]	9	hSpCas9	negative selection	923656
127668143	127668166	9	-	26627737	GBM cells	viability after 5 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.6860486258354708	[149]	[47,51]	-8	hSpCas9	negative selection	923657
127658440	127658463	9	-	26627737	GBM cells	viability after 13 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.2180120977617772	[33]	[11,18]	-3	hSpCas9	negative selection	1005967
127660080	127660103	9	-	26627737	GBM cells	viability after 13 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.8387678036924757	[245]	[230,244]	8	hSpCas9	negative selection	1005968
127663309	127663332	9	-	26627737	GBM cells	viability after 13 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.5231678942037408	[380]	[322,275]	6	hSpCas9	negative selection	1005969
127665264	127665287	9	-	26627737	GBM cells	viability after 13 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.8152838271449907	[160]	[129,172]	8	hSpCas9	negative selection	1005970
127666186	127666209	9	-	26627737	GBM cells	viability after 13 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.2837760725171292	[123]	[98,67]	3	hSpCas9	negative selection	1005971
127668143	127668166	9	-	26627737	GBM cells	viability after 13 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.26660345617959713	[149]	[65,68]	-3	hSpCas9	negative selection	1005972
127658440	127658463	9	-	26627737	GBM cells	viability after 21 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.7182424797155633	[33]	[32,27]	7	hSpCas9	negative selection	1088282
127660080	127660103	9	-	26627737	GBM cells	viability after 21 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	1.0203409667457508	[245]	[268,272]	8	hSpCas9	negative selection	1088283
127663309	127663332	9	-	26627737	GBM cells	viability after 21 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	1.1676385447060775	[380]	[476,453]	9	hSpCas9	negative selection	1088284
127665264	127665287	9	-	26627737	GBM cells	viability after 21 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.0501361753604972	[160]	[189,172]	9	hSpCas9	negative selection	1088285
127666186	127666209	9	-	26627737	GBM cells	viability after 21 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.49724185652259767	[123]	[92,96]	5	hSpCas9	negative selection	1088286
127668143	127668166	9	-	26627737	GBM cells	viability after 21 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.49614257929408057	[149]	[62,52]	-4	hSpCas9	negative selection	1088287
127658440	127658463	9	-	26627737	RPE1	viability after 9 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.1424619397025868	[128]	[20,74]	1	hSpCas9	negative selection	1170597
127660080	127660103	9	-	26627737	RPE1	viability after 9 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.4661258592236014	[1157]	[433,586]	3	hSpCas9	negative selection	1170598
127663309	127663332	9	-	26627737	RPE1	viability after 9 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.3303416699312838	[1577]	[597,650]	2	hSpCas9	negative selection	1170599
127665264	127665287	9	-	26627737	RPE1	viability after 9 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.0885087692927435	[349]	[146,343]	6	hSpCas9	negative selection	1170600
127666186	127666209	9	-	26627737	RPE1	viability after 9 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.9888481771830364	[184]	[55,190]	6	hSpCas9	negative selection	1170601
127668143	127668166	9	-	26627737	RPE1	viability after 9 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.8035320892504697	[819]	[157,132]	-5	hSpCas9	negative selection	1170602
127658440	127658463	9	-	26627737	RPE1	viability after 12 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.8202325718769825	[128]	[6,32]	-5	hSpCas9	negative selection	1252912
127660080	127660103	9	-	26627737	RPE1	viability after 12 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.7707164341667324	[1157]	[421,645]	5	hSpCas9	negative selection	1252913
127663309	127663332	9	-	26627737	RPE1	viability after 12 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.5648802240247957	[1577]	[580,675]	4	hSpCas9	negative selection	1252914
127665264	127665287	9	-	26627737	RPE1	viability after 12 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.3268445383190968	[349]	[231,239]	7	hSpCas9	negative selection	1252915
127666186	127666209	9	-	26627737	RPE1	viability after 12 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.362796475270978	[184]	[60,66]	2	hSpCas9	negative selection	1252916
127668143	127668166	9	-	26627737	RPE1	viability after 12 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.3856634993452675	[819]	[206,127]	-3	hSpCas9	negative selection	1252917
127658440	127658463	9	-	26627737	RPE1	viability after 15 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.46640439955722535	[128]	[54,45]	3	hSpCas9	negative selection	1335227
127660080	127660103	9	-	26627737	RPE1	viability after 15 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.5334925763247896	[1157]	[381,562]	3	hSpCas9	negative selection	1335228
127663309	127663332	9	-	26627737	RPE1	viability after 15 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.5082282745837317	[1577]	[612,655]	3	hSpCas9	negative selection	1335229
127665264	127665287	9	-	26627737	RPE1	viability after 15 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.1366543938805573	[349]	[178,254]	6	hSpCas9	negative selection	1335230
127666186	127666209	9	-	26627737	RPE1	viability after 15 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-0.2254157011757858	[184]	[29,58]	-1	hSpCas9	negative selection	1335231
127668143	127668166	9	-	26627737	RPE1	viability after 15 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.021741140196119613	[819]	[348,125]	0	hSpCas9	negative selection	1335232
127658440	127658463	9	-	26627737	RPE1	viability after 18 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.5896227131844642	[128]	[19,86]	3	hSpCas9	negative selection	1417542
127660080	127660103	9	-	26627737	RPE1	viability after 18 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.5573373905603219	[1157]	[324,603]	3	hSpCas9	negative selection	1417543
127663309	127663332	9	-	26627737	RPE1	viability after 18 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.7827563892296419	[1577]	[663,805]	5	hSpCas9	negative selection	1417544
127665264	127665287	9	-	26627737	RPE1	viability after 18 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.9853150439640677	[349]	[215,155]	6	hSpCas9	negative selection	1417545
127666186	127666209	9	-	26627737	RPE1	viability after 18 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.2303452689802472	[184]	[193,34]	7	hSpCas9	negative selection	1417546
127668143	127668166	9	-	26627737	RPE1	viability after 18 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.5762409968927752	[819]	[400,253]	3	hSpCas9	negative selection	1417547
127658440	127658463	9	-	26627737	HeLa	viability after 8 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	1.212156531290201	[26]	[30,16,33]	8	hSpCas9	negative selection	1499857
127660080	127660103	9	-	26627737	HeLa	viability after 8 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.338939686994425	[525]	[372,344,176]	3	hSpCas9	negative selection	1499858
127663309	127663332	9	-	26627737	HeLa	viability after 8 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.4669247765658329	[392]	[350,171,212]	4	hSpCas9	negative selection	1499859
127665264	127665287	9	-	26627737	HeLa	viability after 8 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.2876126197675884	[328]	[233,168,136]	2	hSpCas9	negative selection	1499860
127666186	127666209	9	-	26627737	HeLa	viability after 8 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.3216149077892942	[123]	[103,161,131]	8	hSpCas9	negative selection	1499861
127668143	127668166	9	-	26627737	HeLa	viability after 8 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.5184877835298715	[186]	[216,159,2]	4	hSpCas9	negative selection	1499862
127658440	127658463	9	-	26627737	HeLa	viability after 12 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.10143651405121101	[26]	[1,9,18]	-1	hSpCas9	negative selection	1582172
127660080	127660103	9	-	26627737	HeLa	viability after 12 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.11837241691019029	[525]	[317,332,48]	1	hSpCas9	negative selection	1582173
127663309	127663332	9	-	26627737	HeLa	viability after 12 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.564833891585172	[392]	[232,197,293]	5	hSpCas9	negative selection	1582174
127665264	127665287	9	-	26627737	HeLa	viability after 12 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	-0.8252146914769928	[328]	[106,20,108]	-6	hSpCas9	negative selection	1582175
127666186	127666209	9	-	26627737	HeLa	viability after 12 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.233326780010988	[123]	[138,91,133]	8	hSpCas9	negative selection	1582176
127668143	127668166	9	-	26627737	HeLa	viability after 12 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.33581132424800075	[186]	[187,61,48]	3	hSpCas9	negative selection	1582177
127658440	127658463	9	-	26627737	HeLa	viability after 15 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	1.6774663505589236	[26]	[10,44,50]	9	hSpCas9	negative selection	1664487
127660080	127660103	9	-	26627737	HeLa	viability after 15 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.23255856903248592	[525]	[290,148,98]	-2	hSpCas9	negative selection	1664488
127663309	127663332	9	-	26627737	HeLa	viability after 15 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.6156832975108223	[392]	[100,237,410]	5	hSpCas9	negative selection	1664489
127665264	127665287	9	-	26627737	HeLa	viability after 15 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	-0.651756213396853	[328]	[118,66,67]	-5	hSpCas9	negative selection	1664490
127666186	127666209	9	-	26627737	HeLa	viability after 15 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.56446366701735	[123]	[114,26,81]	4	hSpCas9	negative selection	1664491
127668143	127668166	9	-	26627737	HeLa	viability after 15 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.45680326089545553	[186]	[3,47,119]	-4	hSpCas9	negative selection	1664492
127658440	127658463	9	-	26627737	HeLa	viability after 18 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	1.626156217789113	[26]	[5,35,50]	9	hSpCas9	negative selection	1746802
127660080	127660103	9	-	26627737	HeLa	viability after 18 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.1493517084583748	[525]	[206,134,98]	-1	hSpCas9	negative selection	1746803
127663309	127663332	9	-	26627737	HeLa	viability after 18 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.6288627427216014	[392]	[68,200,410]	5	hSpCas9	negative selection	1746804
127665264	127665287	9	-	26627737	HeLa	viability after 18 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	-0.614206946342513	[328]	[82,56,67]	-5	hSpCas9	negative selection	1746805
127666186	127666209	9	-	26627737	HeLa	viability after 18 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.5580248547907072	[123]	[79,17,81]	4	hSpCas9	negative selection	1746806
127668143	127668166	9	-	26627737	HeLa	viability after 18 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.4578740521265354	[186]	[3,37,119]	-4	hSpCas9	negative selection	1746807
127658440	127658463	9	-	26627737	HCT116	viability after 6 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-1.4543700177601178	[66]	[8,0]	-7	hSpCas9	negative selection	1829117
127660080	127660103	9	-	26627737	HCT116	viability after 6 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	1.034964618029135	[514]	[123,188]	5	hSpCas9	negative selection	1829118
127663309	127663332	9	-	26627737	HCT116	viability after 6 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.22141871664464186	[1195]	[166,247]	1	hSpCas9	negative selection	1829119
127665264	127665287	9	-	26627737	HCT116	viability after 6 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.0788572668314581	[378]	[89,47]	0	hSpCas9	negative selection	1829120
127666186	127666209	9	-	26627737	HCT116	viability after 6 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-0.6994244272316014	[692]	[59,70]	-4	hSpCas9	negative selection	1829121
127668143	127668166	9	-	26627737	HCT116	viability after 6 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.2863812432806774	[412]	[98,27]	-2	hSpCas9	negative selection	1829122
127658440	127658463	9	-	26627737	HCT116	viability after 8 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.2613919151519295	[36]	[11,26,11]	-3	hSpCas9	negative selection	1911432
127660080	127660103	9	-	26627737	HCT116	viability after 8 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.31190500420924244	[414]	[244,164,438]	3	hSpCas9	negative selection	1911433
127663309	127663332	9	-	26627737	HCT116	viability after 8 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.33313803454872537	[301]	[196,165,264]	3	hSpCas9	negative selection	1911434
127665264	127665287	9	-	26627737	HCT116	viability after 8 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.5010076572411678	[191]	[153,124,169]	5	hSpCas9	negative selection	1911435
127666186	127666209	9	-	26627737	HCT116	viability after 8 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-0.21478931545109547	[155]	[94,87,39]	-2	hSpCas9	negative selection	1911436
127668143	127668166	9	-	26627737	HCT116	viability after 8 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.1030962877133289	[244]	[92,199,83]	-1	hSpCas9	negative selection	1911437
127658440	127658463	9	-	26627737	HCT116	viability after 9 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.9868484522592018	[66]	[3,12]	-6	hSpCas9	negative selection	1993747
127660080	127660103	9	-	26627737	HCT116	viability after 9 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.10654137435931635	[514]	[137,155]	0	hSpCas9	negative selection	1993748
127663309	127663332	9	-	26627737	HCT116	viability after 9 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.36559461780043556	[1195]	[511,331]	2	hSpCas9	negative selection	1993749
127665264	127665287	9	-	26627737	HCT116	viability after 9 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.5907913134313947	[378]	[253,344]	8	hSpCas9	negative selection	1993750
127666186	127666209	9	-	26627737	HCT116	viability after 9 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-1.5884677339563982	[692]	[65,57]	-8	hSpCas9	negative selection	1993751
127668143	127668166	9	-	26627737	HCT116	viability after 9 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-1.322625640336693	[412]	[47,40]	-7	hSpCas9	negative selection	1993752
127658440	127658463	9	-	26627737	HCT116	viability after 12 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.4960101284668532	[36]	[1,47,34]	5	hSpCas9	negative selection	2076062
127660080	127660103	9	-	26627737	HCT116	viability after 12 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.029436768958355397	[414]	[131,244,271]	0	hSpCas9	negative selection	2076063
127663309	127663332	9	-	26627737	HCT116	viability after 12 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.5326669718166183	[301]	[156,264,273]	5	hSpCas9	negative selection	2076064
127665264	127665287	9	-	26627737	HCT116	viability after 12 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.3469987315166085	[191]	[188,257,328]	8	hSpCas9	negative selection	2076065
127666186	127666209	9	-	26627737	HCT116	viability after 12 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.4288301935045543	[155]	[74,143,115]	4	hSpCas9	negative selection	2076066
127668143	127668166	9	-	26627737	HCT116	viability after 12 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.3390574331903291	[244]	[21,168,122]	-4	hSpCas9	negative selection	2076067
127658440	127658463	9	-	26627737	HCT116	viability after 15 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.15845507934098535	[36]	[5,39,22]	1	hSpCas9	negative selection	2158377
127660080	127660103	9	-	26627737	HCT116	viability after 15 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.12956924215926435	[414]	[215,189,246]	-1	hSpCas9	negative selection	2158378
127663309	127663332	9	-	26627737	HCT116	viability after 15 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.6223241651378433	[301]	[287,206,307]	5	hSpCas9	negative selection	2158379
127665264	127665287	9	-	26627737	HCT116	viability after 15 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	1.1749047544068572	[191]	[243,314,187]	8	hSpCas9	negative selection	2158380
127666186	127666209	9	-	26627737	HCT116	viability after 15 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.3617881448975484	[155]	[93,149,98]	3	hSpCas9	negative selection	2158381
127668143	127668166	9	-	26627737	HCT116	viability after 15 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.26355760335741185	[244]	[145,163,45]	-3	hSpCas9	negative selection	2158382
127658440	127658463	9	-	26627737	HCT116	viability after 18 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-1.3870774072266032	[36]	[10,0,8]	-8	hSpCas9	negative selection	2240692
127660080	127660103	9	-	26627737	HCT116	viability after 18 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.6259382607993729	[414]	[369,197,370]	5	hSpCas9	negative selection	2240693
127663309	127663332	9	-	26627737	HCT116	viability after 18 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	-0.32684665118218825	[301]	[100,115,132]	-3	hSpCas9	negative selection	2240694
127665264	127665287	9	-	26627737	HCT116	viability after 18 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.8176385112145379	[191]	[222,128,139]	6	hSpCas9	negative selection	2240695
127666186	127666209	9	-	26627737	HCT116	viability after 18 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	-0.3186842554724053	[155]	[24,69,86]	-3	hSpCas9	negative selection	2240696
127668143	127668166	9	-	26627737	HCT116	viability after 18 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.15133272489597932	[244]	[28,120,171]	-1	hSpCas9	negative selection	2240697
127669671	127669694	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTCGAACTCCCAACCTCAGG	STXBP1	ENSG00000136854	-0.16266902606406886	[97,288]	[29,46]	0	dCas9-VP64	positive selection	2385187
127612061	127612084	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGGCTCCGCACCAGCCAGCGG	STXBP1	ENSG00000136854	-1.0062859308569574	[86,9]	[7,0]	-6	dCas9-VP64	positive selection	2390829
127612088	127612111	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGCGCCCAGCCGCATCTCGGG	STXBP1	ENSG00000136854	0.29199982861629015	[146,129]	[33,40]	1	dCas9-VP64	positive selection	2390830
127612038	127612061	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGCGTGAGGTGAGGGGGAGGG	STXBP1	ENSG00000136854	0.9176205359958978	[3,8]	[0,3]	4	dCas9-VP64	positive selection	2390831
127626139	127626162	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAAAATTAGCCGGGTGTCGTGG	STXBP1	ENSG00000136854	-0.26513306153968963	[62,264]	[7,53]	-1	dCas9-VP64	positive selection	2415312
127650211	127650234	9	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACACACACACACACAGCAG	STXBP1	ENSG00000136854	0.19128589643959537	[429,108]	[111,17]	0	dCas9-VP64	positive selection	2424215
127659407	127659430	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCACCTCAGCCTCCCAAACAG	STXBP1	ENSG00000136854	-0.684504052123245	[138,151]	[23,13]	-3	dCas9-VP64	positive selection	2425561
127650493	127650516	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGGTGG	STXBP1	ENSG00000136854	1.250295307438589	[24,5]	[12,2]	5	dCas9-VP64	positive selection	2434558
127621964	127621987	9	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCAATTGCACTCCAGCCTGGG	STXBP1	ENSG00000136854	1.5824467828014601	[76,203]	[81,104]	6	dCas9-VP64	positive selection	2438406
127669671	127669694	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTCGAACTCCCAACCTCAGG	STXBP1	ENSG00000136854	0.7537551994741627	[30,51]	[21,22]	5	dCas9-VP64	positive selection	2480442
127612061	127612084	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGGCTCCGCACCAGCCAGCGG	STXBP1	ENSG00000136854	1.496496920387954	[68,55]	[97,19]	8	dCas9-VP64	positive selection	2486084
127612088	127612111	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGCGCCCAGCCGCATCTCGGG	STXBP1	ENSG00000136854	-0.22870352558884838	[84,270]	[65,32]	-2	dCas9-VP64	positive selection	2486085
127612038	127612061	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGCGTGAGGTGAGGGGGAGGG	STXBP1	ENSG00000136854	-0.2374028169316138	[59,56]	[19,11]	-2	dCas9-VP64	positive selection	2486086
127626139	127626162	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAAAATTAGCCGGGTGTCGTGG	STXBP1	ENSG00000136854	0.8001190132117662	[123,184]	[163,14]	5	dCas9-VP64	positive selection	2510567
127650211	127650234	9	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACACACACACACACAGCAG	STXBP1	ENSG00000136854	-0.29192793722986554	[278,490]	[95,106]	-3	dCas9-VP64	positive selection	2519470
127659407	127659430	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCACCTCAGCCTCCCAAACAG	STXBP1	ENSG00000136854	0.29312304600633954	[90,145]	[39,52]	2	dCas9-VP64	positive selection	2520816
127650493	127650516	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGGTGG	STXBP1	ENSG00000136854	0.8668431868856517	[26,20]	[22,6]	6	dCas9-VP64	positive selection	2529813
127621964	127621987	9	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCAATTGCACTCCAGCCTGGG	STXBP1	ENSG00000136854	0.9485671343767268	[153,312]	[141,149]	6	dCas9-VP64	positive selection	2533661
127666224	127666247	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	0.3103359660939899	[3,3]	[4,3]	6	hSpCas9	positive selection	3024525
127668159	127668182	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.33663659992389405	[2,2]	[2,0]	-5	hSpCas9	positive selection	3024526
127666224	127666247	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	0.4775669391417126	[3,3]	[4,3]	7	hSpCas9	positive selection	3092383
127668159	127668182	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.4298384470037653	[2,2]	[0,1]	-6	hSpCas9	positive selection	3092384
127666169	127666192		-	24336571	A375	resistance to PLX after 7 days	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.2970195902737842	[62,62]	[72,80]	7	hSpCas9	positive selection	3148206
127666234	127666257		-	24336571	A375	resistance to PLX after 7 days	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	-0.06553485615162569	[19,24]	[20,20]	-2	hSpCas9	positive selection	3148209
127651607	127651630		+	24336571	A375	resistance to PLX after 7 days	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.2772674338966957	[8,7]	[8,11]	7	hSpCas9	positive selection	3148210
127666169	127666192		-	24336571	A375	resistance to PLX after 14 days	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.8440590828297809	[59,79]	[58,58]	7	hSpCas9	positive selection	3205999
127666234	127666257		-	24336571	A375	resistance to PLX after 14 days	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	0.1277207764148024	[20,17]	[10,8]	1	hSpCas9	positive selection	3206002
127651607	127651630		+	24336571	A375	resistance to PLX after 14 days	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.5371868855075594	[11,9]	[8,5]	5	hSpCas9	positive selection	3206003
127666169	127666192		-	24336571	A375	viability after 7 days	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.7446264302649059	[38]	[62,62]	9	hSpCas9	negative selection	3263792
127666234	127666257		-	24336571	A375	viability after 7 days	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	0.401978063119789	[17]	[19,24]	6	hSpCas9	negative selection	3263795
127651607	127651630		+	24336571	A375	viability after 7 days	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.5818305764067507	[13]	[8,7]	-7	hSpCas9	negative selection	3263796
127666169	127666192		-	24336571	A375	viability after 14 days	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.9120867516298248	[38]	[59,79]	9	hSpCas9	negative selection	3321585
127666234	127666257		-	24336571	A375	viability after 14 days	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	0.2444923234857561	[17]	[20,17]	3	hSpCas9	negative selection	3321588
127651607	127651630		+	24336571	A375	viability after 14 days	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.2477081130370581	[13]	[11,9]	-3	hSpCas9	negative selection	3321589
127668088	127668111	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3395557
127651607	127651630	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.7815927778464674	[262,262]	[0,0]	-5	hSpCas9	positive selection	3395558
127651631	127651654	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	3.7978945928085377	[10,10]	[0,0]	9	hSpCas9	positive selection	3395559
127663237	127663260	9	+	26780180	HT29	viability (Avana library 4 designs)	AAGCTTCTACAGTCCCCACAAGG	STXBP1	ENSG00000136854	1.1949779178912	[]	[]	4	hSpCas9	negative selection	3463216
127658400	127658423	9	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCCGCTCCCCAGCCTGGAGG	STXBP1	ENSG00000136854	3.21397478505159	[]	[]	8	hSpCas9	negative selection	3463217
127666224	127666247	9	-	26780180	HT29	viability (Avana library 4 designs)	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	0.450338602369591	[]	[]	1	hSpCas9	negative selection	3463218
127668158	127668181	9	+	26780180	HT29	viability (Avana library 4 designs)	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	1.1918865654883	[]	[]	4	hSpCas9	negative selection	3463219
127658400	127658423	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCCGCTCCCCAGCCTGGAGG	STXBP1	ENSG00000136854	-3.1301320518257	[]	[]	-4	hSpCas9	negative selection	3565156
127663237	127663260	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCTTCTACAGTCCCCACAAGG	STXBP1	ENSG00000136854	3.78002892246616	[]	[]	6	hSpCas9	negative selection	3565157
127666224	127666247	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	-3.54205263314757	[]	[]	-4	hSpCas9	negative selection	3565158
127668158	127668181	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-4.10409311333302	[]	[]	-5	hSpCas9	negative selection	3565159
127658400	127658423	9	+	26780180	A375	viability (Avana lentiGuide)	AGAGCCGCTCCCCAGCCTGGAGG	STXBP1	ENSG00000136854	25.8348077187799	[]	[]	9	hSpCas9	negative selection	3673815
127663237	127663260	9	+	26780180	A375	viability (Avana lentiGuide)	AAGCTTCTACAGTCCCCACAAGG	STXBP1	ENSG00000136854	0.834156870101644	[]	[]	1	hSpCas9	negative selection	3673816
127666224	127666247	9	-	26780180	A375	viability (Avana lentiGuide)	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	-2.02874158066487	[]	[]	-3	hSpCas9	negative selection	3673817
127668158	127668181	9	+	26780180	A375	viability (Avana lentiGuide)	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	4.61856750170829	[]	[]	4	hSpCas9	negative selection	3673818
127658400	127658423	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCCGCTCCCCAGCCTGGAGG	STXBP1	ENSG00000136854	-0.37809154163444403	[5]	[5,3]	-5	hSpCas9	positive selection	3782422
127663237	127663260	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCTTCTACAGTCCCCACAAGG	STXBP1	ENSG00000136854	-0.022641984194936963	[5]	[5,4]	0	hSpCas9	positive selection	3782423
127666224	127666247	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	-0.47451658131325714	[5]	[4,2]	-6	hSpCas9	positive selection	3782424
127668158	127668181	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	0.008777953270320271	[3]	[4,2]	0	hSpCas9	positive selection	3782425
127658400	127658423	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCCGCTCCCCAGCCTGGAGG	STXBP1	ENSG00000136854	-0.6014916835981152	[6]	[2,3]	-6	hSpCas9	positive selection	3891029
127663237	127663260	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCTTCTACAGTCCCCACAAGG	STXBP1	ENSG00000136854	-0.029987725550539263	[5]	[6,2]	0	hSpCas9	positive selection	3891030
127666224	127666247	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCAATTCATGGAGCACAGGGG	STXBP1	ENSG00000136854	0.275606600972396	[5]	[5,5]	7	hSpCas9	positive selection	3891031
127668158	127668181	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.12348431799733695	[4]	[3,2]	-2	hSpCas9	positive selection	3891032
127666169	127666192	9	-	26780180	A375	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.565951746073782	[]	[]	1	hSpCas9	negative selection	4000693
127651631	127651654	9	+	26780180	A375	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	1.85353166236756	[]	[]	9	hSpCas9	negative selection	4000694
127668088	127668111	9	-	26780180	A375	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.882842795938779	[]	[]	3	hSpCas9	negative selection	4000695
127651607	127651630	9	+	26780180	A375	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.720888922920843	[]	[]	2	hSpCas9	negative selection	4000696
127668127	127668150	9	+	26780180	A375	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.862999571017543	[]	[]	3	hSpCas9	negative selection	4000697
127666198	127666221	9	-	26780180	A375	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	1.5162915697564	[]	[]	8	hSpCas9	negative selection	4000698
127666169	127666192	9	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.56502123280581	[]	[]	2	hSpCas9	negative selection	4108659
127651631	127651654	9	+	26780180	HT29	viability (GeCKOv2 library)	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	2.45243073024945	[]	[]	9	hSpCas9	negative selection	4108660
127668088	127668111	9	-	26780180	HT29	viability (GeCKOv2 library)	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	1.32511410486219	[]	[]	6	hSpCas9	negative selection	4108661
127651607	127651630	9	+	26780180	HT29	viability (GeCKOv2 library)	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.6537941755686	[]	[]	2	hSpCas9	negative selection	4108662
127668127	127668150	9	+	26780180	HT29	viability (GeCKOv2 library)	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.371302059540238	[]	[]	1	hSpCas9	negative selection	4108663
127666198	127666221	9	-	26780180	HT29	viability (GeCKOv2 library)	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	1.39089662843458	[]	[]	7	hSpCas9	negative selection	4108664
127666169	127666192	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.3622670680048148	[5]	[4,5]	8	hSpCas9	positive selection	4174453
127666234	127666257	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	0.16566960013210003	[4]	[3,3]	4	hSpCas9	positive selection	4174456
127651607	127651630	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.12978741767753874	[3]	[2,2]	3	hSpCas9	positive selection	4174457
127666169	127666192	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.22403272331908075	[4]	[4,2,2,0]	1	hSpCas9	positive selection	4238475
127666234	127666257	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGCCTGAAAAGTCAATTCATGG	STXBP1	ENSG00000136854	0.38936608804949463	[4]	[4,3,3,0]	3	hSpCas9	positive selection	4238478
127651607	127651630	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.9173855716238055	[4]	[2,4,3,3]	6	hSpCas9	positive selection	4238479
127666198	127666221	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.5872287735191142	[2]	[2,0]	-8	hSpCas9	positive selection	4301287
127666169	127666192	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.17648310333810968	[4]	[4,2]	3	hSpCas9	positive selection	4301288
127668127	127668150	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	-0.0045864728522602705	[3]	[3,2]	0	hSpCas9	positive selection	4301289
127668088	127668111	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.24858800427400538	[2]	[3,2]	5	hSpCas9	positive selection	4365542
127651607	127651630	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.04683642857005006	[3]	[2,2]	-1	hSpCas9	positive selection	4365543
127651631	127651654	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.1757029190101902	[2]	[0,0]	-9	hSpCas9	positive selection	4365544
127658440	127658462	9	-	27760321	OCIAML3	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.03339436455693501	[210,146]	[116,158]	0	hSpCas9	negative selection	4444211
127660063	127660085	9	+	27760321	OCIAML3	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	-0.6524366242007846	[630,453]	[284,243]	-6	hSpCas9	negative selection	4444212
127663288	127663310	9	-	27760321	OCIAML3	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.20458391134086362	[1083,933]	[855,972]	2	hSpCas9	negative selection	4444213
127663333	127663355	9	+	27760321	OCIAML3	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	-0.15046272412092032	[978,860]	[603,702]	-2	hSpCas9	negative selection	4444214
127668080	127668102	9	+	27760321	OCIAML3	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.042219458435387436	[646,541]	[442,520]	0	hSpCas9	negative selection	4444215
127658440	127658462	9	-	27760321	OCIAML2	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.407710443085199	[210,146]	[78,145]	-5	hSpCas9	negative selection	4527674
127660063	127660085	9	+	27760321	OCIAML2	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	-0.1810496341626021	[630,453]	[396,364]	-2	hSpCas9	negative selection	4527675
127663288	127663310	9	-	27760321	OCIAML2	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.27874568034020464	[1083,933]	[841,1178]	3	hSpCas9	negative selection	4527676
127663333	127663355	9	+	27760321	OCIAML2	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.06967944719057662	[978,860]	[785,770]	0	hSpCas9	negative selection	4527677
127668080	127668102	9	+	27760321	OCIAML2	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	-0.24222768180353124	[646,541]	[344,483]	-3	hSpCas9	negative selection	4527678
127658440	127658462	9	-	27760321	MV411	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-3.4092658457753013	[210,146]	[0,25]	-9	hSpCas9	negative selection	4611137
127660063	127660085	9	+	27760321	MV411	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	-0.5579046541933504	[630,453]	[149,376]	-4	hSpCas9	negative selection	4611138
127663288	127663310	9	-	27760321	MV411	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.9069015320918057	[1083,933]	[933,1711]	6	hSpCas9	negative selection	4611139
127663333	127663355	9	+	27760321	MV411	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.38697570339288734	[978,860]	[928,586]	2	hSpCas9	negative selection	4611140
127668080	127668102	9	+	27760321	MV411	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	-0.22503658056337983	[646,541]	[478,116]	-2	hSpCas9	negative selection	4611141
127658440	127658462	9	-	27760321	HL60	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.19252440043699792	[210,146]	[154,175]	2	hSpCas9	negative selection	4694600
127660063	127660085	9	+	27760321	HL60	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.22786924752886634	[630,453]	[620,399]	2	hSpCas9	negative selection	4694601
127663288	127663310	9	-	27760321	HL60	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.18216412278646787	[1083,933]	[982,878]	2	hSpCas9	negative selection	4694602
127663333	127663355	9	+	27760321	HL60	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.028707060611943946	[978,860]	[801,725]	0	hSpCas9	negative selection	4694603
127668080	127668102	9	+	27760321	HL60	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	-0.14687641805023027	[646,541]	[399,475]	-2	hSpCas9	negative selection	4694604
127658440	127658462	9	-	27760321	HT1080	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.6738176602731049	[146,114]	[130,30]	3	hSpCas9	negative selection	4778063
127660063	127660085	9	+	27760321	HT1080	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	-0.6244680385451349	[453,353]	[80,129]	-3	hSpCas9	negative selection	4778064
127663288	127663310	9	-	27760321	HT1080	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.6529731098047418	[933,728]	[580,454]	3	hSpCas9	negative selection	4778065
127663333	127663355	9	+	27760321	HT1080	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	-0.22586328068788042	[860,671]	[199,327]	-1	hSpCas9	negative selection	4778066
127668080	127668102	9	+	27760321	HT1080	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.7530515556748559	[541,422]	[364,278]	4	hSpCas9	negative selection	4778067
127658440	127658462	9	-	27760321	HT29	viability after 7 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.004181789355239385	[146,114]	[201,130,177]	0	hSpCas9	negative selection	4861526
127660063	127660085	9	+	27760321	HT29	viability after 7 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.27561433863161	[453,353]	[624,574,682]	4	hSpCas9	negative selection	4861527
127663288	127663310	9	-	27760321	HT29	viability after 7 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.32187109456214036	[933,728]	[1655,1170,1228]	5	hSpCas9	negative selection	4861528
127663333	127663355	9	+	27760321	HT29	viability after 7 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.1580046577652181	[860,671]	[1142,1114,1046]	2	hSpCas9	negative selection	4861529
127668080	127668102	9	+	27760321	HT29	viability after 7 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.4397929914828236	[541,422]	[1356,440,799]	6	hSpCas9	negative selection	4861530
127658440	127658462	9	-	27760321	HT29	viability after 25 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.08109558677690898	[146,114]	[126,176,118]	-1	hSpCas9	negative selection	4944989
127660063	127660085	9	+	27760321	HT29	viability after 25 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.0587602438213935	[453,353]	[531,439,464]	0	hSpCas9	negative selection	4944990
127663288	127663310	9	-	27760321	HT29	viability after 25 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.5222298010274711	[933,728]	[1135,1558,1416]	6	hSpCas9	negative selection	4944991
127663333	127663355	9	+	27760321	HT29	viability after 25 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.13686449401014933	[860,671]	[960,964,961]	1	hSpCas9	negative selection	4944992
127668080	127668102	9	+	27760321	HT29	viability after 25 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.09763676559974155	[541,422]	[747,379,635]	1	hSpCas9	negative selection	4944993
127658440	127658462	9	-	27760321	HT29	viability after 22 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.30604474794507075	[146,114]	[174,209,176]	3	hSpCas9	negative selection	5028452
127660063	127660085	9	+	27760321	HT29	viability after 22 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.029621486769401933	[453,353]	[358,521,552]	0	hSpCas9	negative selection	5028453
127663288	127663310	9	-	27760321	HT29	viability after 22 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.48319571462579014	[933,728]	[1048,1223,1769]	5	hSpCas9	negative selection	5028454
127663333	127663355	9	+	27760321	HT29	viability after 22 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.2589660085342371	[860,671]	[1504,1017,641]	2	hSpCas9	negative selection	5028455
127668080	127668102	9	+	27760321	HT29	viability after 22 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.30547815967272995	[541,422]	[953,503,601]	3	hSpCas9	negative selection	5028456
127658440	127658462	9	-	27760321	HT29	viability after 19 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.1238896220381902	[146,114]	[118,193,98]	-1	hSpCas9	negative selection	5111915
127660063	127660085	9	+	27760321	HT29	viability after 19 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.15716269611022446	[453,353]	[562,304,675]	1	hSpCas9	negative selection	5111916
127663288	127663310	9	-	27760321	HT29	viability after 19 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.5319963052916696	[933,728]	[1476,1152,1499]	5	hSpCas9	negative selection	5111917
127663333	127663355	9	+	27760321	HT29	viability after 19 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.3950391629220542	[860,671]	[793,1153,1459]	4	hSpCas9	negative selection	5111918
127668080	127668102	9	+	27760321	HT29	viability after 19 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.13619360265319835	[541,422]	[856,376,610]	1	hSpCas9	negative selection	5111919
127658440	127658462	9	-	27760321	HT29	viability after 16 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.01297013318162099	[146,114]	[156,245,38]	0	hSpCas9	negative selection	5195378
127660063	127660085	9	+	27760321	HT29	viability after 16 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.30624381075350937	[453,353]	[685,385,620]	3	hSpCas9	negative selection	5195379
127663288	127663310	9	-	27760321	HT29	viability after 16 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.53953312397701	[933,728]	[1076,1172,1784]	6	hSpCas9	negative selection	5195380
127663333	127663355	9	+	27760321	HT29	viability after 16 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.07432091171729316	[860,671]	[1043,821,857]	0	hSpCas9	negative selection	5195381
127668080	127668102	9	+	27760321	HT29	viability after 16 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.3804243795562695	[541,422]	[789,749,574]	4	hSpCas9	negative selection	5195382
127658440	127658462	9	-	27760321	HT29	viability after 13 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.03665705080338544	[146,114]	[213,92,137]	0	hSpCas9	negative selection	5278841
127660063	127660085	9	+	27760321	HT29	viability after 13 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.2803307663777109	[453,353]	[511,514,673]	3	hSpCas9	negative selection	5278842
127663288	127663310	9	-	27760321	HT29	viability after 13 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.4633649518773517	[933,728]	[1205,1504,1281]	6	hSpCas9	negative selection	5278843
127663333	127663355	9	+	27760321	HT29	viability after 13 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	0.13884547665570923	[860,671]	[1115,1085,748]	1	hSpCas9	negative selection	5278844
127668080	127668102	9	+	27760321	HT29	viability after 13 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.21466487991432326	[541,422]	[713,458,767]	2	hSpCas9	negative selection	5278845
127658440	127658462	9	-	27760321	HT29	viability after 10 days	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.020355056034454977	[146,114]	[98,131,249]	0	hSpCas9	negative selection	5362304
127660063	127660085	9	+	27760321	HT29	viability after 10 days	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	0.2914662520689094	[453,353]	[489,837,531]	4	hSpCas9	negative selection	5362305
127663288	127663310	9	-	27760321	HT29	viability after 10 days	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	0.5312136856294682	[933,728]	[1488,1350,1652]	7	hSpCas9	negative selection	5362306
127663333	127663355	9	+	27760321	HT29	viability after 10 days	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	-0.14004566277836938	[860,671]	[951,904,751]	-2	hSpCas9	negative selection	5362307
127668080	127668102	9	+	27760321	HT29	viability after 10 days	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	-0.05457375418194732	[541,422]	[671,536,530]	0	hSpCas9	negative selection	5362308
127658440	127658462	9	-	27760321	MOLM13	viability	GAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-1.6925053949741407	[210,146]	[65,0]	-7	hSpCas9	negative selection	5445767
127660063	127660085	9	+	27760321	MOLM13	viability	CCGCCGACTGCTAAATACCGGG	STXBP1	ENSG00000136854	-0.8027110468273979	[630,453]	[271,89]	-5	hSpCas9	negative selection	5445768
127663288	127663310	9	-	27760321	MOLM13	viability	GGTCGCGATCTGCTCTGCCAGG	STXBP1	ENSG00000136854	1.3673276194129547	[1083,933]	[2539,548]	8	hSpCas9	negative selection	5445769
127663333	127663355	9	+	27760321	MOLM13	viability	CCCGGCTGTGCGGTATCGGGGG	STXBP1	ENSG00000136854	-0.261678878195597	[978,860]	[571,312]	-2	hSpCas9	negative selection	5445770
127668080	127668102	9	+	27760321	MOLM13	viability	GTATGAGACCAGCGGCATCGGG	STXBP1	ENSG00000136854	0.9297049988151396	[646,541]	[1000,325]	6	hSpCas9	negative selection	5445771
127612272	127612295	9	+	27661255	K562	viability	GCGTCAGTCGGTCCCTAGCGCGG	STXBP1	ENSG00000136854	-0.036263724380408036	[1250,1077]	[996,834]	-1	dCas9-KRAB	negative selection	5515067
127612262	127612285	9	-	27661255	K562	viability	GACCGACTGACGCGCGGACTGGG	STXBP1	ENSG00000136854	0.18150456811564913	[543,517]	[569,405]	6	dCas9-KRAB	negative selection	5515068
127612268	127612291	9	-	27661255	K562	viability	GCTAGGGACCGACTGACGCGCGG	STXBP1	ENSG00000136854	0.3254443944690071	[203,200]	[212,193]	9	dCas9-KRAB	negative selection	5515069
127612640	127612663	9	-	27661255	K562	viability	GAGGGCTGGGGTGAAACATGAGG	STXBP1	ENSG00000136854	0.06737674014204875	[1282,1397]	[1035,1191]	2	dCas9-KRAB	negative selection	5515070
127612693	127612716	9	-	27661255	K562	viability	GACAGGGACCGCGAGGAAGGAGG	STXBP1	ENSG00000136854	0.03326654166820009	[1601,1484]	[1446,1106]	1	dCas9-KRAB	negative selection	5515071
127612696	127612719	9	-	27661255	K562	viability	GGAGACAGGGACCGCGAGGAAGG	STXBP1	ENSG00000136854	0.03159894827343082	[923,830]	[807,640]	1	dCas9-KRAB	negative selection	5515072
127666198	127666221	9	-	27260156	BXPC3	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.24336647646320814	[356]	[251,343,336,333]	-5	hSpCas9	negative selection	5573747
127666169	127666192	9	-	27260156	BXPC3	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.25256547726934286	[1041]	[1005,1316,1397,1521]	5	hSpCas9	negative selection	5573748
127668127	127668150	9	+	27260156	BXPC3	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.37422260012669517	[675]	[887,1067,763,930]	7	hSpCas9	negative selection	5573749
127668088	127668111	9	-	27260156	BXPC3	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.10146776452672249	[443]	[491,475,484,542]	2	hSpCas9	negative selection	5638002
127651607	127651630	9	+	27260156	BXPC3	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.17244469440821	[615]	[498,567,525,713]	-4	hSpCas9	negative selection	5638003
127651631	127651654	9	+	27260156	BXPC3	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.684020644279698	[272]	[27,53,49,46]	-9	hSpCas9	negative selection	5638004
127666198	127666221	9	-	27260156	A673	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.15797291530911	[356]	[483,342,396,320]	-4	hSpCas9	negative selection	5694998
127666169	127666192	9	-	27260156	A673	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.1995494829818194	[1041]	[1548,1162,1462,1597]	5	hSpCas9	negative selection	5694999
127668127	127668150	9	+	27260156	A673	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.2820135605081556	[675]	[1075,969,982,923]	6	hSpCas9	negative selection	5695000
127668088	127668111	9	-	27260156	A673	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.037108622689575	[443]	[738,522,402,545]	0	hSpCas9	negative selection	5759253
127651607	127651630	9	+	27260156	A673	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.20869241545274336	[615]	[695,633,520,719]	-5	hSpCas9	negative selection	5759254
127651631	127651654	9	+	27260156	A673	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.1712761717585711	[272]	[172,97,141,174]	-9	hSpCas9	negative selection	5759255
127666198	127666221	9	-	27260156	A375	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.14420116132233773	[356]	[265,672,381,538]	2	hSpCas9	negative selection	5816249
127666169	127666192	9	-	27260156	A375	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.5623583249422501	[1041]	[1672,2552,1429,1647]	8	hSpCas9	negative selection	5816250
127668127	127668150	9	+	27260156	A375	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.1545529476507298	[675]	[934,878,769,922]	2	hSpCas9	negative selection	5816251
127668088	127668111	9	-	27260156	A375	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.3252518558795867	[443]	[691,568,651,669]	5	hSpCas9	negative selection	5880504
127651607	127651630	9	+	27260156	A375	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.1484573504876423	[615]	[530,818,730,547]	-2	hSpCas9	negative selection	5880505
127651631	127651654	9	+	27260156	A375	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.517620045105788	[272]	[148,183,71,56]	-9	hSpCas9	negative selection	5880506
127666198	127666221	9	-	27260156	COLO741	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.06012552745543809	[356]	[601,524,320]	1	hSpCas9	negative selection	5937500
127666169	127666192	9	-	27260156	COLO741	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.20738309275110778	[1041]	[1589,1394,1620]	4	hSpCas9	negative selection	5937501
127668127	127668150	9	+	27260156	COLO741	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3684470797795635	[675]	[1254,1064,1039]	7	hSpCas9	negative selection	5937502
127668088	127668111	9	-	27260156	COLO741	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.2724241205473108	[443]	[828,579,658]	6	hSpCas9	negative selection	6001755
127651607	127651630	9	+	27260156	COLO741	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.1893451281807649	[615]	[650,710,702]	-4	hSpCas9	negative selection	6001756
127651631	127651654	9	+	27260156	COLO741	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.066813601530188	[272]	[33,148,63]	-9	hSpCas9	negative selection	6001757
127666198	127666221	9	-	27260156	CAL120	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.07843633462029065	[356]	[649,469,316]	1	hSpCas9	negative selection	6058751
127666169	127666192	9	-	27260156	CAL120	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.21821901641158248	[1041]	[1282,1607,1597]	3	hSpCas9	negative selection	6058752
127668127	127668150	9	+	27260156	CAL120	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.45004708817221406	[675]	[968,1195,1252]	6	hSpCas9	negative selection	6058753
127668088	127668111	9	-	27260156	CAL120	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	-0.018592537653769323	[443]	[708,423,527]	0	hSpCas9	negative selection	6123006
127651607	127651630	9	+	27260156	CAL120	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.19616600740043968	[615]	[712,653,646]	-3	hSpCas9	negative selection	6123007
127651631	127651654	9	+	27260156	CAL120	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.9147542032499367	[272]	[32,212,16]	-9	hSpCas9	negative selection	6123008
127666198	127666221	9	-	27260156	CADOES1	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.09916247672534878	[356]	[288,331,359,256]	-2	hSpCas9	negative selection	6180002
127666169	127666192	9	-	27260156	CADOES1	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.22672226069531898	[1041]	[1014,1233,1144,1142]	4	hSpCas9	negative selection	6180003
127668127	127668150	9	+	27260156	CADOES1	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.18717216081681265	[675]	[578,744,661,883]	3	hSpCas9	negative selection	6180004
127668088	127668111	9	-	27260156	CADOES1	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.15561718454160686	[443]	[504,608,422,296]	2	hSpCas9	negative selection	6244257
127651607	127651630	9	+	27260156	CADOES1	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.225319764732598	[615]	[489,432,474,564]	-4	hSpCas9	negative selection	6244258
127651631	127651654	9	+	27260156	CADOES1	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.4246913387983318	[272]	[22,187,39,128]	-9	hSpCas9	negative selection	6244259
127666198	127666221	9	-	27260156	EWS502	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.0998927925780006	[356]	[340,342,408,316]	-2	hSpCas9	negative selection	6301253
127666169	127666192	9	-	27260156	EWS502	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.25423174872145893	[1041]	[1114,1380,1185,1619]	4	hSpCas9	negative selection	6301254
127668127	127668150	9	+	27260156	EWS502	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.4329049502867265	[675]	[815,894,969,1220]	7	hSpCas9	negative selection	6301255
127668088	127668111	9	-	27260156	EWS502	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.20245069216074257	[443]	[555,483,557,566]	3	hSpCas9	negative selection	6365508
127651607	127651630	9	+	27260156	EWS502	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.05543350707490419	[615]	[677,676,602,755]	1	hSpCas9	negative selection	6365509
127651631	127651654	9	+	27260156	EWS502	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-4.1295612675222815	[272]	[5,19,28,11]	-9	hSpCas9	negative selection	6365510
127666198	127666221	9	-	27260156	EW8	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.041972861967458364	[356]	[448,240,214,315]	0	hSpCas9	negative selection	6422504
127666169	127666192	9	-	27260156	EW8	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.09035787264170048	[1041]	[959,955,915,765]	1	hSpCas9	negative selection	6422505
127668127	127668150	9	+	27260156	EW8	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3172636909290868	[675]	[733,884,512,631]	6	hSpCas9	negative selection	6422506
127668088	127668111	9	-	27260156	EW8	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.1269892941069359	[443]	[479,297,330,480]	2	hSpCas9	negative selection	6486759
127651607	127651630	9	+	27260156	EW8	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.08832391985803184	[615]	[663,410,375,462]	-2	hSpCas9	negative selection	6486760
127651631	127651654	9	+	27260156	EW8	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.8034018510096805	[272]	[54,44,100,44]	-9	hSpCas9	negative selection	6486761
127666198	127666221	9	-	27260156	CORL105	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.2778846125698084	[356]	[559,412,511,545]	5	hSpCas9	negative selection	6543755
127666169	127666192	9	-	27260156	CORL105	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.25459823849954044	[1041]	[1314,1321,1615,1589]	5	hSpCas9	negative selection	6543756
127668127	127668150	9	+	27260156	CORL105	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3590049822756731	[675]	[1166,926,978,987]	6	hSpCas9	negative selection	6543757
127668088	127668111	9	-	27260156	CORL105	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.20382054916103431	[443]	[515,518,626,734]	4	hSpCas9	negative selection	6608010
127651607	127651630	9	+	27260156	CORL105	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.2864724686931078	[615]	[592,608,630,537]	-5	hSpCas9	negative selection	6608011
127651631	127651654	9	+	27260156	CORL105	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.500726578664707	[272]	[87,99,156,112]	-9	hSpCas9	negative selection	6608012
127666198	127666221	9	-	27260156	HS294T	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.5881278581211143	[356]	[214,173,141,316]	7	hSpCas9	negative selection	6665006
127666169	127666192	9	-	27260156	HS294T	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.25058947689520306	[1041]	[557,476,463,394]	3	hSpCas9	negative selection	6665007
127668127	127668150	9	+	27260156	HS294T	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.4338151867394563	[675]	[336,240,457,385]	6	hSpCas9	negative selection	6665008
127668088	127668111	9	-	27260156	HS294T	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.5083551747933751	[443]	[255,362,155,185]	6	hSpCas9	negative selection	6729261
127651607	127651630	9	+	27260156	HS294T	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.7856424720883202	[615]	[102,111,180,164]	-8	hSpCas9	negative selection	6729262
127651631	127651654	9	+	27260156	HS294T	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.8591712065580515	[272]	[6,17,12,21]	-9	hSpCas9	negative selection	6729263
127666198	127666221	9	-	27260156	HCC44	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.14847429283448993	[356]	[338,345,388,383]	-2	hSpCas9	negative selection	6786257
127666169	127666192	9	-	27260156	HCC44	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.16584279369554622	[1041]	[1413,1331,1473,1097]	2	hSpCas9	negative selection	6786258
127668127	127668150	9	+	27260156	HCC44	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.5063080274315518	[675]	[964,799,1442,1213]	8	hSpCas9	negative selection	6786259
127668088	127668111	9	-	27260156	HCC44	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.2435089615925239	[443]	[478,667,877,382]	4	hSpCas9	negative selection	6850512
127651607	127651630	9	+	27260156	HCC44	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.2881010764269863	[615]	[728,408,640,548]	-4	hSpCas9	negative selection	6850513
127651631	127651654	9	+	27260156	HCC44	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.9957030944726704	[272]	[12,103,5,14]	-9	hSpCas9	negative selection	6850514
127666198	127666221	9	-	27260156	G402	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.012719720287409919	[356]	[591,743,170,295]	0	hSpCas9	negative selection	6907508
127666169	127666192	9	-	27260156	G402	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.2885289649880418	[1041]	[1836,1368,1814,1230]	3	hSpCas9	negative selection	6907509
127668127	127668150	9	+	27260156	G402	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.22281881643375434	[675]	[866,978,1239,757]	3	hSpCas9	negative selection	6907510
127668088	127668111	9	-	27260156	G402	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.6733370654348331	[443]	[594,1374,514,953]	8	hSpCas9	negative selection	6971763
127651607	127651630	9	+	27260156	G402	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.3718292682798377	[615]	[642,428,596,648]	-5	hSpCas9	negative selection	6971764
127651631	127651654	9	+	27260156	G402	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.2787710748203516	[272]	[32,16,37,172]	-9	hSpCas9	negative selection	6971765
127666198	127666221	9	-	27260156	L33	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.060134206043419236	[356]	[285,166,255,389]	1	hSpCas9	negative selection	7028759
127666169	127666192	9	-	27260156	L33	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.11844087244969304	[1041]	[1154,581,575,1031]	2	hSpCas9	negative selection	7028760
127668127	127668150	9	+	27260156	L33	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.5309581620388127	[675]	[999,401,563,1026]	9	hSpCas9	negative selection	7028761
127668088	127668111	9	-	27260156	L33	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.35595525403918504	[443]	[702,205,378,461]	7	hSpCas9	negative selection	7093014
127651607	127651630	9	+	27260156	L33	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.2583916367308665	[615]	[410,242,289,595]	-5	hSpCas9	negative selection	7093015
127651631	127651654	9	+	27260156	L33	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.8497958607963816	[272]	[48,37,53,75]	-9	hSpCas9	negative selection	7093016
127666198	127666221	9	-	27260156	K562	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.14585447697251047	[356]	[151,392,252,334]	-2	hSpCas9	negative selection	7150010
127666169	127666192	9	-	27260156	K562	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.5849146757358838	[1041]	[1933,998,1307,1331]	7	hSpCas9	negative selection	7150011
127668127	127668150	9	+	27260156	K562	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3164187160944324	[675]	[502,1408,805,330]	4	hSpCas9	negative selection	7150012
127668088	127668111	9	-	27260156	K562	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.4825738518817256	[443]	[582,595,740,312]	6	hSpCas9	negative selection	7214265
127651607	127651630	9	+	27260156	K562	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.07222021833040204	[615]	[777,521,449,366]	-1	hSpCas9	negative selection	7214266
127651631	127651654	9	+	27260156	K562	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.5530485334517445	[272]	[21,9,24,97]	-9	hSpCas9	negative selection	7214267
127666198	127666221	9	-	27260156	HT29	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.058458910537356024	[356]	[399,451,408,405]	-1	hSpCas9	negative selection	7271261
127666169	127666192	9	-	27260156	HT29	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.11632576368902892	[1041]	[1322,1498,1463,1221]	2	hSpCas9	negative selection	7271262
127668127	127668150	9	+	27260156	HT29	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3060491455025204	[675]	[1080,1039,1110,851]	6	hSpCas9	negative selection	7271263
127668088	127668111	9	-	27260156	HT29	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.3425762959712059	[443]	[626,532,949,613]	6	hSpCas9	negative selection	7335516
127651607	127651630	9	+	27260156	HT29	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.10462866950012539	[615]	[779,852,663,524]	-2	hSpCas9	negative selection	7335517
127651631	127651654	9	+	27260156	HT29	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-3.1478985821400536	[272]	[30,30,53,32]	-9	hSpCas9	negative selection	7335518
127666198	127666221	9	-	27260156	MHHES1	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.38196100998408605	[356]	[566,599,633,339]	7	hSpCas9	negative selection	7392512
127666169	127666192	9	-	27260156	MHHES1	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.2574188595635749	[1041]	[1796,1719,1432,841]	5	hSpCas9	negative selection	7392513
127668127	127668150	9	+	27260156	MHHES1	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.506022131935535	[675]	[1141,1420,1089,763]	8	hSpCas9	negative selection	7392514
127668088	127668111	9	-	27260156	MHHES1	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.46623527499822875	[443]	[689,860,752,504]	7	hSpCas9	negative selection	7456767
127651607	127651630	9	+	27260156	MHHES1	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.11637111357115909	[615]	[929,919,606,605]	2	hSpCas9	negative selection	7456768
127651631	127651654	9	+	27260156	MHHES1	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.5449823611019249	[272]	[90,108,123,95]	-9	hSpCas9	negative selection	7456769
127666198	127666221	9	-	27260156	MEWO	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.0293905698893015	[356]	[436,372,230]	0	hSpCas9	negative selection	7513763
127666169	127666192	9	-	27260156	MEWO	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.262574593111466	[1041]	[1630,865,1101]	5	hSpCas9	negative selection	7513764
127668127	127668150	9	+	27260156	MEWO	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.5059999476408984	[675]	[1113,901,719]	8	hSpCas9	negative selection	7513765
127668088	127668111	9	-	27260156	MEWO	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.2579134534274933	[443]	[447,610,420]	5	hSpCas9	negative selection	7578018
127651607	127651630	9	+	27260156	MEWO	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.1471150322157642	[615]	[464,612,471]	-3	hSpCas9	negative selection	7578019
127651631	127651654	9	+	27260156	MEWO	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.731676784566707	[272]	[87,44,99]	-9	hSpCas9	negative selection	7578020
127666198	127666221	9	-	27260156	LNCAPCLONEFGC	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.07889524568330708	[356]	[308,275,509,300]	1	hSpCas9	negative selection	7635014
127666169	127666192	9	-	27260156	LNCAPCLONEFGC	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.5227157660098993	[1041]	[1280,1103,1662,1438]	7	hSpCas9	negative selection	7635015
127668127	127668150	9	+	27260156	LNCAPCLONEFGC	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.37357816572904146	[675]	[844,683,839,816]	6	hSpCas9	negative selection	7635016
127668088	127668111	9	-	27260156	LNCAPCLONEFGC	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.4082771485560502	[443]	[380,508,760,521]	6	hSpCas9	negative selection	7699269
127651607	127651630	9	+	27260156	LNCAPCLONEFGC	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.22307914964394462	[615]	[397,479,569,478]	-4	hSpCas9	negative selection	7699270
127651631	127651654	9	+	27260156	LNCAPCLONEFGC	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.885065181746452	[272]	[29,43,51,9]	-9	hSpCas9	negative selection	7699271
127666198	127666221	9	-	27260156	PANC0327	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.17082584632508147	[356]	[522,360,335,220]	2	hSpCas9	negative selection	7756265
127666169	127666192	9	-	27260156	PANC0327	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.3946802116555128	[1041]	[1218,1116,1182,1360]	6	hSpCas9	negative selection	7756266
127668127	127668150	9	+	27260156	PANC0327	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.1523629224167502	[675]	[546,469,783,883]	2	hSpCas9	negative selection	7756267
127668088	127668111	9	-	27260156	PANC0327	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.278408119636143	[443]	[396,442,428,641]	4	hSpCas9	negative selection	7820520
127651607	127651630	9	+	27260156	PANC0327	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.3724647260002253	[615]	[603,354,297,456]	-5	hSpCas9	negative selection	7820521
127651631	127651654	9	+	27260156	PANC0327	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-3.6084615707811447	[272]	[64,5,5,7]	-9	hSpCas9	negative selection	7820522
127666198	127666221	9	-	27260156	NCIH2009	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.18985183534265415	[356]	[639,562,516]	2	hSpCas9	negative selection	7877516
127666169	127666192	9	-	27260156	NCIH2009	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.49540110651734603	[1041]	[2248,1794,2152]	6	hSpCas9	negative selection	7877517
127668127	127668150	9	+	27260156	NCIH2009	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3790266108456456	[675]	[1232,1262,1186]	5	hSpCas9	negative selection	7877518
127668088	127668111	9	-	27260156	NCIH2009	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.38976490884531695	[443]	[876,1009,558]	5	hSpCas9	negative selection	7941771
127651607	127651630	9	+	27260156	NCIH2009	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.4714328089065172	[615]	[728,651,500]	-6	hSpCas9	negative selection	7941772
127651631	127651654	9	+	27260156	NCIH2009	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.4911103612964602	[272]	[16,87,87]	-9	hSpCas9	negative selection	7941773
127666198	127666221	9	-	27260156	NCIH1373	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.12000857082075761	[356]	[565,410,207,81]	-1	hSpCas9	negative selection	7998767
127666169	127666192	9	-	27260156	NCIH1373	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.5133162035792767	[1041]	[1553,1623,1430,542]	5	hSpCas9	negative selection	7998768
127668127	127668150	9	+	27260156	NCIH1373	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.10910335703046314	[675]	[1093,695,525,268]	1	hSpCas9	negative selection	7998769
127668088	127668111	9	-	27260156	NCIH1373	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.17285895365884202	[443]	[786,401,597,131]	1	hSpCas9	negative selection	8063022
127651607	127651630	9	+	27260156	NCIH1373	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.30820241986092	[615]	[873,218,585,167]	-3	hSpCas9	negative selection	8063023
127651631	127651654	9	+	27260156	NCIH1373	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.3164384751187113	[272]	[54,112,182,33]	-8	hSpCas9	negative selection	8063024
127666198	127666221	9	-	27260156	PATU8902	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.047828770299983114	[356]	[769,406,354,407]	0	hSpCas9	negative selection	8120018
127666169	127666192	9	-	27260156	PATU8902	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.3504471527797932	[1041]	[1856,2186,1124,2481]	3	hSpCas9	negative selection	8120019
127668127	127668150	9	+	27260156	PATU8902	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.17212519389022185	[675]	[1371,1278,713,941]	1	hSpCas9	negative selection	8120020
127668088	127668111	9	-	27260156	PATU8902	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.353758559334653	[443]	[833,562,759,1032]	3	hSpCas9	negative selection	8184273
127651607	127651630	9	+	27260156	PATU8902	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.09915722488224454	[615]	[686,1245,755,484]	-1	hSpCas9	negative selection	8184274
127651631	127651654	9	+	27260156	PATU8902	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-4.709709958501026	[272]	[28,1,3,26]	-9	hSpCas9	negative selection	8184275
127666198	127666221	9	-	27260156	PANC1	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.20397808060854078	[356]	[353,275,291,156]	-3	hSpCas9	negative selection	8241269
127666169	127666192	9	-	27260156	PANC1	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.26572105840983595	[1041]	[1171,1337,961,894]	4	hSpCas9	negative selection	8241270
127668127	127668150	9	+	27260156	PANC1	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.39163064208865406	[675]	[613,875,973,621]	6	hSpCas9	negative selection	8241271
127668088	127668111	9	-	27260156	PANC1	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.16853818207089855	[443]	[434,420,450,402]	2	hSpCas9	negative selection	8305524
127651607	127651630	9	+	27260156	PANC1	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.12173756818510295	[615]	[344,682,536,425]	-2	hSpCas9	negative selection	8305525
127651631	127651654	9	+	27260156	PANC1	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.1975780592630128	[272]	[51,52,67,33]	-9	hSpCas9	negative selection	8305526
127666198	127666221	9	-	27260156	PANC0813	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.10006216904154097	[356]	[513,289,555,443]	1	hSpCas9	negative selection	8362520
127666169	127666192	9	-	27260156	PANC0813	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.2821839445819214	[1041]	[1424,1388,1350,1763]	4	hSpCas9	negative selection	8362521
127668127	127668150	9	+	27260156	PANC0813	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.491498175573552	[675]	[1215,1172,1119,971]	7	hSpCas9	negative selection	8362522
127668088	127668111	9	-	27260156	PANC0813	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.5379364542391878	[443]	[974,685,865,533]	8	hSpCas9	negative selection	8426775
127651607	127651630	9	+	27260156	PANC0813	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.045370934034403676	[615]	[593,1018,677,512]	0	hSpCas9	negative selection	8426776
127651631	127651654	9	+	27260156	PANC0813	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.053921296356406	[272]	[62,80,128,36]	-9	hSpCas9	negative selection	8426777
127666198	127666221	9	-	27260156	RDES	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.016776701959162754	[356]	[428,325,353,517]	0	hSpCas9	negative selection	8483771
127666169	127666192	9	-	27260156	RDES	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.34622763367470455	[1041]	[1365,1342,1690,1734]	5	hSpCas9	negative selection	8483772
127668127	127668150	9	+	27260156	RDES	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.21676179616418634	[675]	[748,913,937,1038]	3	hSpCas9	negative selection	8483773
127668088	127668111	9	-	27260156	RDES	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.18238907064814158	[443]	[509,547,647,619]	3	hSpCas9	negative selection	8548026
127651607	127651630	9	+	27260156	RDES	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.35373162805508	[615]	[543,525,553,583]	-6	hSpCas9	negative selection	8548027
127651631	127651654	9	+	27260156	RDES	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.297304873329755	[272]	[71,52,51,76]	-9	hSpCas9	negative selection	8548028
127666198	127666221	9	-	27260156	PC3	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.09696423917667013	[356]	[216,330,503,363]	-2	hSpCas9	negative selection	8605022
127666169	127666192	9	-	27260156	PC3	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.08242794378098761	[1041]	[975,839,1924,893]	1	hSpCas9	negative selection	8605023
127668127	127668150	9	+	27260156	PC3	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3712910857824647	[675]	[602,950,1060,967]	7	hSpCas9	negative selection	8605024
127668088	127668111	9	-	27260156	PC3	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.12731886771604167	[443]	[297,444,845,524]	3	hSpCas9	negative selection	8669277
127651607	127651630	9	+	27260156	PC3	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.1177388758584989	[615]	[389,625,1072,376]	-3	hSpCas9	negative selection	8669278
127651631	127651654	9	+	27260156	PC3	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.618843582545043	[272]	[58,112,165,46]	-9	hSpCas9	negative selection	8669279
127666198	127666221	9	-	27260156	PATU8988T	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.40306080178936493	[356]	[587,429,403,395]	7	hSpCas9	negative selection	8726273
127666169	127666192	9	-	27260156	PATU8988T	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.3716768213286912	[1041]	[1382,1393,1176,1263]	6	hSpCas9	negative selection	8726274
127668127	127668150	9	+	27260156	PATU8988T	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.2033933785570614	[675]	[626,917,689,792]	3	hSpCas9	negative selection	8726275
127668088	127668111	9	-	27260156	PATU8988T	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.6120472502492152	[443]	[625,829,733,429]	8	hSpCas9	negative selection	8790528
127651607	127651630	9	+	27260156	PATU8988T	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.026207403798459206	[615]	[726,692,578,418]	0	hSpCas9	negative selection	8790529
127651631	127651654	9	+	27260156	PATU8988T	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.2818370721525771	[272]	[91,122,172,40]	-9	hSpCas9	negative selection	8790530
127666198	127666221	9	-	27260156	T47D	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.14402480080377095	[356]	[361,383,373,384]	-3	hSpCas9	negative selection	8847524
127666169	127666192	9	-	27260156	T47D	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	-0.04271214407422819	[1041]	[1325,1112,1105,1175]	-1	hSpCas9	negative selection	8847525
127668127	127668150	9	+	27260156	T47D	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.09589954521685806	[675]	[836,776,971,781]	2	hSpCas9	negative selection	8847526
127668088	127668111	9	-	27260156	T47D	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.10876364354763915	[443]	[582,487,591,573]	2	hSpCas9	negative selection	8911779
127651607	127651630	9	+	27260156	T47D	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.1108968138619989	[615]	[651,670,673,659]	-2	hSpCas9	negative selection	8911780
127651631	127651654	9	+	27260156	T47D	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.7586492135860654	[272]	[108,65,112,89]	-9	hSpCas9	negative selection	8911781
127666198	127666221	9	-	27260156	SU8686	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	0.21514986480103282	[356]	[314,269,477,646]	3	hSpCas9	negative selection	8968775
127666169	127666192	9	-	27260156	SU8686	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.3419688118585471	[1041]	[1173,1068,1475,1608]	6	hSpCas9	negative selection	8968776
127668127	127668150	9	+	27260156	SU8686	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.455954364223632	[675]	[919,844,805,1141]	7	hSpCas9	negative selection	8968777
127668088	127668111	9	-	27260156	SU8686	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.31162397348252824	[443]	[599,535,466,575]	5	hSpCas9	negative selection	9033030
127651607	127651630	9	+	27260156	SU8686	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.3496739395544973	[615]	[503,426,434,563]	-5	hSpCas9	negative selection	9033031
127651631	127651654	9	+	27260156	SU8686	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-2.377832106521699	[272]	[37,25,86,64]	-9	hSpCas9	negative selection	9033032
127666198	127666221	9	-	27260156	SKES1	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.3340471455127591	[356]	[329,291,246,267]	-6	hSpCas9	negative selection	9090026
127666169	127666192	9	-	27260156	SKES1	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.09279693898947672	[1041]	[1456,1199,1025,832]	2	hSpCas9	negative selection	9090027
127668127	127668150	9	+	27260156	SKES1	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.0708407786145937	[675]	[939,820,589,541]	1	hSpCas9	negative selection	9090028
127668088	127668111	9	-	27260156	SKES1	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.0859112893201269	[443]	[405,508,590,374]	2	hSpCas9	negative selection	9154281
127651607	127651630	9	+	27260156	SKES1	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.24887310555155778	[615]	[617,597,533,355]	-5	hSpCas9	negative selection	9154282
127651631	127651654	9	+	27260156	SKES1	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-1.241504604225074	[272]	[108,142,154,60]	-9	hSpCas9	negative selection	9154283
127666198	127666221	9	-	27260156	TOV112D	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.10867148763847906	[356]	[376,282,443,216]	-2	hSpCas9	negative selection	9211277
127666169	127666192	9	-	27260156	TOV112D	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.1198729827707734	[1041]	[911,1533,961,1203]	2	hSpCas9	negative selection	9211278
127668127	127668150	9	+	27260156	TOV112D	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.29267703012987667	[675]	[847,1102,573,858]	5	hSpCas9	negative selection	9211279
127668088	127668111	9	-	27260156	TOV112D	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.010886825318620258	[443]	[363,588,305,556]	0	hSpCas9	negative selection	9275532
127651607	127651630	9	+	27260156	TOV112D	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.35869354118149654	[615]	[451,462,416,581]	-6	hSpCas9	negative selection	9275533
127651631	127651654	9	+	27260156	TOV112D	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-0.9500298190916511	[272]	[99,141,196,123]	-9	hSpCas9	negative selection	9275534
127666198	127666221	9	-	27260156	TC71	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.16225452295494386	[356]	[336,414,376,230]	-4	hSpCas9	negative selection	9332528
127666169	127666192	9	-	27260156	TC71	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.048695601511455466	[1041]	[1256,1117,1149,1089]	1	hSpCas9	negative selection	9332529
127668127	127668150	9	+	27260156	TC71	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.3496258383014207	[675]	[944,836,863,1056]	8	hSpCas9	negative selection	9332530
127668088	127668111	9	-	27260156	TC71	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.077647521992038	[443]	[499,515,524,464]	2	hSpCas9	negative selection	9396783
127651607	127651630	9	+	27260156	TC71	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	-0.06307792536934548	[615]	[766,674,515,566]	-1	hSpCas9	negative selection	9396784
127651631	127651654	9	+	27260156	TC71	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-0.6907332195514707	[272]	[143,218,151,213]	-9	hSpCas9	negative selection	9396785
127666198	127666221	9	-	27260156	TC32	viability	TGGGGTCAAAGCCTCGATCCAGG	STXBP1	ENSG00000136854	-0.14670079903537564	[356]	[224,222,422,389]	-3	hSpCas9	negative selection	9453779
127666169	127666192	9	-	27260156	TC32	viability	AGCTGGGAGCGTGCCTTGTCTGG	STXBP1	ENSG00000136854	0.18112250743654368	[1041]	[870,1095,1344,1135]	3	hSpCas9	negative selection	9453780
127668127	127668150	9	+	27260156	TC32	viability	TGGACGAGGACGACGACCTGTGG	STXBP1	ENSG00000136854	0.32653089368283195	[675]	[568,654,1016,1032]	6	hSpCas9	negative selection	9453781
127668088	127668111	9	-	27260156	TC32	viability	CCGTGCCTCCCCGATGCCGCTGG	STXBP1	ENSG00000136854	0.375429138746887	[443]	[526,452,808,416]	6	hSpCas9	negative selection	9518034
127651607	127651630	9	+	27260156	TC32	viability	TATGCATGATGTGATAAAGAAGG	STXBP1	ENSG00000136854	0.06436511843472781	[615]	[583,408,730,769]	1	hSpCas9	negative selection	9518035
127651631	127651654	9	+	27260156	TC32	viability	CAAGAAGAAGGGGGAATGGAAGG	STXBP1	ENSG00000136854	-0.9228134190041487	[272]	[84,140,187,131]	-9	hSpCas9	negative selection	9518036
127658440	127658463	9	-	27869803	HPAFII	viability after 27 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.1782065564410953	[45]	[52,5,NaN]	1	hSpCas9	negative selection	9604442
127660080	127660103	9	-	27869803	HPAFII	viability after 27 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.17982103758481233	[331]	[200,114,NaN]	-1	hSpCas9	negative selection	9604443
127663309	127663332	9	-	27869803	HPAFII	viability after 27 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	1.0862895852538879	[239]	[232,296,NaN]	8	hSpCas9	negative selection	9604444
127665264	127665287	9	-	27869803	HPAFII	viability after 27 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.3064617759927481	[190]	[157,95,NaN]	2	hSpCas9	negative selection	9604445
127666186	127666209	9	-	27869803	HPAFII	viability after 27 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.7284351124363722	[103]	[136,217,NaN]	9	hSpCas9	negative selection	9604446
127668143	127668166	9	-	27869803	HPAFII	viability after 27 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.5197346406601488	[284]	[282,157,NaN]	4	hSpCas9	negative selection	9604447
127658440	127658463	9	-	27869803	HPAFII	viability after 15 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.447692483213187	[45]	[162,7,NaN]	5	hSpCas9	negative selection	9686891
127660080	127660103	9	-	27869803	HPAFII	viability after 15 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.10555046014170816	[331]	[669,205,NaN]	1	hSpCas9	negative selection	9686892
127663309	127663332	9	-	27869803	HPAFII	viability after 15 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.47606605697922294	[239]	[433,311,NaN]	5	hSpCas9	negative selection	9686893
127665264	127665287	9	-	27869803	HPAFII	viability after 15 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.29960435555991166	[190]	[272,239,NaN]	3	hSpCas9	negative selection	9686894
127666186	127666209	9	-	27869803	HPAFII	viability after 15 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.0097183326572037	[103]	[274,193,NaN]	9	hSpCas9	negative selection	9686895
127668143	127668166	9	-	27869803	HPAFII	viability after 15 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.048323256886696114	[284]	[384,240,NaN]	0	hSpCas9	negative selection	9686896
127658440	127658463	9	-	27869803	ASPC1	viability after 36 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-1.2604588592342783	[99]	[39,8,0]	-8	hSpCas9	negative selection	9769340
127660080	127660103	9	-	27869803	ASPC1	viability after 36 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	1.2861194300291339	[746]	[814,322,751]	9	hSpCas9	negative selection	9769341
127663309	127663332	9	-	27869803	ASPC1	viability after 36 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	-0.7639948445362156	[954]	[282,119,193]	-6	hSpCas9	negative selection	9769342
127665264	127665287	9	-	27869803	ASPC1	viability after 36 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.4132691524870392	[523]	[149,348,222]	4	hSpCas9	negative selection	9769343
127666186	127666209	9	-	27869803	ASPC1	viability after 36 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.2978032415988079	[332]	[158,239,52]	3	hSpCas9	negative selection	9769344
127668143	127668166	9	-	27869803	ASPC1	viability after 36 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.4362222717719492	[513]	[64,111,194]	-4	hSpCas9	negative selection	9769345
127658440	127658463	9	-	27869803	PATU8988S	viability after 35 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.5606619807884168	[31]	[22,14,NaN]	6	hSpCas9	negative selection	9851789
127660080	127660103	9	-	27869803	PATU8988S	viability after 35 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.46091809484118945	[620]	[235,452,NaN]	5	hSpCas9	negative selection	9851790
127663309	127663332	9	-	27869803	PATU8988S	viability after 35 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	1.0420722147202561	[774]	[745,538,NaN]	9	hSpCas9	negative selection	9851791
127665264	127665287	9	-	27869803	PATU8988S	viability after 35 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.02671364399905468	[384]	[138,176,NaN]	0	hSpCas9	negative selection	9851792
127666186	127666209	9	-	27869803	PATU8988S	viability after 35 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.09686907189360139	[253]	[66,151,NaN]	1	hSpCas9	negative selection	9851793
127668143	127668166	9	-	27869803	PATU8988S	viability after 35 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.25724451623778055	[528]	[291,63,NaN]	-3	hSpCas9	negative selection	9851794
127658440	127658463	9	-	27869803	PATU8988S	viability after 31 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	0.7567585338349181	[31]	[21,20,NaN]	8	hSpCas9	negative selection	9934238
127660080	127660103	9	-	27869803	PATU8988S	viability after 31 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	0.18921545530548134	[620]	[291,269,NaN]	2	hSpCas9	negative selection	9934239
127663309	127663332	9	-	27869803	PATU8988S	viability after 31 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	0.7534349455067149	[774]	[505,539,NaN]	8	hSpCas9	negative selection	9934240
127665264	127665287	9	-	27869803	PATU8988S	viability after 31 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	-0.3296610641641664	[384]	[104,143,NaN]	-4	hSpCas9	negative selection	9934241
127666186	127666209	9	-	27869803	PATU8988S	viability after 31 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	0.003811215814070401	[253]	[46,170,NaN]	0	hSpCas9	negative selection	9934242
127668143	127668166	9	-	27869803	PATU8988S	viability after 31 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	-0.5527323051647045	[528]	[145,140,NaN]	-6	hSpCas9	negative selection	9934243
127658440	127658463	9	-	27869803	HPAFII	viability after 35 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.853810728636208	[45]	[18,5,NaN]	-5	hSpCas9	negative selection	10016687
127660080	127660103	9	-	27869803	HPAFII	viability after 35 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.020214836493789856	[331]	[224,98,NaN]	0	hSpCas9	negative selection	10016688
127663309	127663332	9	-	27869803	HPAFII	viability after 35 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	1.4404138368650865	[239]	[174,503,NaN]	8	hSpCas9	negative selection	10016689
127665264	127665287	9	-	27869803	HPAFII	viability after 35 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.8392879525976511	[190]	[53,306,NaN]	5	hSpCas9	negative selection	10016690
127666186	127666209	9	-	27869803	HPAFII	viability after 35 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.915347677114575	[103]	[96,312,NaN]	9	hSpCas9	negative selection	10016691
127668143	127668166	9	-	27869803	HPAFII	viability after 35 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.04325898440713827	[284]	[198,91,NaN]	0	hSpCas9	negative selection	10016692
127658440	127658463	9	-	27869803	HPAFII	viability after 31 days	GGAAGGTTTACCTTCTCGGATGG	STXBP1	ENSG00000136854	-0.17561758355199686	[45]	[41,1,NaN]	-1	hSpCas9	negative selection	10099136
127660080	127660103	9	-	27869803	HPAFII	viability after 31 days	TGAAGAAGACGTGTGCAGCCCGG	STXBP1	ENSG00000136854	-0.20417375372454263	[331]	[233,82,NaN]	-1	hSpCas9	negative selection	10099137
127663309	127663332	9	-	27869803	HPAFII	viability after 31 days	ACTCCTTCAGGGTGGCACAAAGG	STXBP1	ENSG00000136854	1.1732212025598825	[239]	[152,467,NaN]	8	hSpCas9	negative selection	10099138
127665264	127665287	9	-	27869803	HPAFII	viability after 31 days	CTGGATTAGCTGAGCCAGCAGGG	STXBP1	ENSG00000136854	0.6940807355430548	[190]	[126,223,NaN]	5	hSpCas9	negative selection	10099139
127666186	127666209	9	-	27869803	HPAFII	viability after 31 days	CTCGATCCAGGATCAGGAGCTGG	STXBP1	ENSG00000136854	1.881603552201239	[103]	[104,334,NaN]	9	hSpCas9	negative selection	10099140
127668143	127668166	9	-	27869803	HPAFII	viability after 31 days	TGTGGCGCAGTGCTATCCACAGG	STXBP1	ENSG00000136854	0.14353635272417278	[284]	[202,147,NaN]	1	hSpCas9	negative selection	10099141
127668158	127668181	9	+	28162770	P31FUJ	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.11207630609237274	[400]	[435]	-1	hSpCas9	negative selection	10245073
127658409	127658432	9	-	28162770	P31FUJ	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.36330085391197775	[42]	[64]	4	hSpCas9	negative selection	10245074
127653766	127653789	9	+	28162770	P31FUJ	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.004236992886470878	[223]	[263]	0	hSpCas9	negative selection	10245075
127668083	127668106	9	+	28162770	P31FUJ	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	-1.6138923717698845	[111]	[42]	-7	hSpCas9	negative selection	10245076
127676633	127676656	9	+	28162770	P31FUJ	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-0.11250797069666696	[22]	[24]	-1	hSpCas9	negative selection	10245077
127678483	127678506	9	+	28162770	P31FUJ	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.7946810920224934	[61]	[41]	-6	hSpCas9	negative selection	10245078
127678511	127678534	9	+	28162770	P31FUJ	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.09134941268177177	[388]	[486]	0	hSpCas9	negative selection	10245079
127680212	127680235	9	-	28162770	P31FUJ	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.4254472823567745	[287]	[125]	-7	hSpCas9	negative selection	10245080
127682437	127682460	9	+	28162770	P31FUJ	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.7633169211131584	[207]	[143]	-5	hSpCas9	negative selection	10245081
127682463	127682486	9	-	28162770	P31FUJ	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.9648689991677455	[97]	[58]	-6	hSpCas9	negative selection	10245082
127668158	127668181	9	+	28162770	TF1	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10414439
127658409	127658432	9	-	28162770	TF1	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10414440
127653766	127653789	9	+	28162770	TF1	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10414441
127668083	127668106	9	+	28162770	TF1	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10414442
127676633	127676656	9	+	28162770	TF1	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10414443
127678483	127678506	9	+	28162770	TF1	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10414444
127678511	127678534	9	+	28162770	TF1	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	NaN	[NaN]	[370]	1	hSpCas9	negative selection	10414445
127680212	127680235	9	-	28162770	TF1	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10414446
127682437	127682460	9	+	28162770	TF1	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10414447
127682463	127682486	9	-	28162770	TF1	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10414448
127668158	127668181	9	+	28162770	SKM1	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.2889669893447103	[131]	[190]	-2	hSpCas9	negative selection	10583805
127658409	127658432	9	-	28162770	SKM1	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	1.1414724259528801	[9]	[38]	9	hSpCas9	negative selection	10583806
127653766	127653789	9	+	28162770	SKM1	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.4038797093943224	[58]	[137]	4	hSpCas9	negative selection	10583807
127668083	127668106	9	+	28162770	SKM1	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.5105736410648652	[26]	[67]	5	hSpCas9	negative selection	10583808
127676633	127676656	9	+	28162770	SKM1	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.5405683813627027	[13]	[35]	5	hSpCas9	negative selection	10583809
127678483	127678506	9	+	28162770	SKM1	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	1.0848888975865132	[11]	[44]	8	hSpCas9	negative selection	10583810
127678511	127678534	9	+	28162770	SKM1	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.10946692030717886	[96]	[184]	1	hSpCas9	negative selection	10583811
127680212	127680235	9	-	28162770	SKM1	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-2.1643938954690833	[70]	[27]	-8	hSpCas9	negative selection	10583812
127682437	127682460	9	+	28162770	SKM1	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-1.0443941193584534	[41]	[35]	-6	hSpCas9	negative selection	10583813
127682463	127682486	9	-	28162770	SKM1	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.056466951659028375	[19]	[33]	0	hSpCas9	negative selection	10583814
127668158	127668181	9	+	28162770	SKM1	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.2889669893447103	[131]	[190]	-2	hSpCas9	negative selection	10753171
127658409	127658432	9	-	28162770	SKM1	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	1.1414724259528801	[9]	[38]	9	hSpCas9	negative selection	10753172
127653766	127653789	9	+	28162770	SKM1	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.4038797093943224	[58]	[137]	4	hSpCas9	negative selection	10753173
127668083	127668106	9	+	28162770	SKM1	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.5105736410648652	[26]	[67]	5	hSpCas9	negative selection	10753174
127676633	127676656	9	+	28162770	SKM1	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.5405683813627027	[13]	[35]	5	hSpCas9	negative selection	10753175
127678483	127678506	9	+	28162770	SKM1	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	1.0848888975865132	[11]	[44]	8	hSpCas9	negative selection	10753176
127678511	127678534	9	+	28162770	SKM1	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.10946692030717886	[96]	[184]	1	hSpCas9	negative selection	10753177
127680212	127680235	9	-	28162770	SKM1	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-2.1643938954690833	[70]	[27]	-8	hSpCas9	negative selection	10753178
127682437	127682460	9	+	28162770	SKM1	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-1.0443941193584534	[41]	[35]	-6	hSpCas9	negative selection	10753179
127682463	127682486	9	-	28162770	SKM1	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.056466951659028375	[19]	[33]	0	hSpCas9	negative selection	10753180
127668158	127668181	9	+	28162770	PL21	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	0.12248705883685562	[457]	[216]	1	hSpCas9	negative selection	10922537
127658409	127658432	9	-	28162770	PL21	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.762018502097435	[41]	[30]	6	hSpCas9	negative selection	10922538
127653766	127653789	9	+	28162770	PL21	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.24257488080971662	[267]	[137]	2	hSpCas9	negative selection	10922539
127668083	127668106	9	+	28162770	PL21	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.9154101375562073	[66]	[54]	7	hSpCas9	negative selection	10922540
127676633	127676656	9	+	28162770	PL21	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-4.085262604372929	[38]	[0]	-9	hSpCas9	negative selection	10922541
127678483	127678506	9	+	28162770	PL21	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.26452865251412416	[68]	[24]	-2	hSpCas9	negative selection	10922542
127678511	127678534	9	+	28162770	PL21	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.16374379683942064	[313]	[121]	-1	hSpCas9	negative selection	10922543
127680212	127680235	9	-	28162770	PL21	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.3479233034203069	[192]	[32]	-7	hSpCas9	negative selection	10922544
127682437	127682460	9	+	28162770	PL21	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	0.21145492771715424	[126]	[63]	1	hSpCas9	negative selection	10922545
127682463	127682486	9	-	28162770	PL21	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-2.5003001036517727	[38]	[2]	-9	hSpCas9	negative selection	10922546
127668158	127668181	9	+	28162770	P31FUJ	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.11207630609237274	[400]	[435]	-1	hSpCas9	negative selection	11091903
127658409	127658432	9	-	28162770	P31FUJ	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.36330085391197775	[42]	[64]	4	hSpCas9	negative selection	11091904
127653766	127653789	9	+	28162770	P31FUJ	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.004236992886470878	[223]	[263]	0	hSpCas9	negative selection	11091905
127668083	127668106	9	+	28162770	P31FUJ	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	-1.6138923717698845	[111]	[42]	-7	hSpCas9	negative selection	11091906
127676633	127676656	9	+	28162770	P31FUJ	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-0.11250797069666696	[22]	[24]	-1	hSpCas9	negative selection	11091907
127678483	127678506	9	+	28162770	P31FUJ	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.7946810920224934	[61]	[41]	-6	hSpCas9	negative selection	11091908
127678511	127678534	9	+	28162770	P31FUJ	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.09134941268177177	[388]	[486]	0	hSpCas9	negative selection	11091909
127680212	127680235	9	-	28162770	P31FUJ	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.4254472823567745	[287]	[125]	-7	hSpCas9	negative selection	11091910
127682437	127682460	9	+	28162770	P31FUJ	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.7633169211131584	[207]	[143]	-5	hSpCas9	negative selection	11091911
127682463	127682486	9	-	28162770	P31FUJ	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.9648689991677455	[97]	[58]	-6	hSpCas9	negative selection	11091912
127668158	127668181	9	+	28162770	OCIAML5	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.10329167440815745	[218]	[367]	0	hSpCas9	negative selection	11261269
127658409	127658432	9	-	28162770	OCIAML5	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	1.0410182252194908	[13]	[51]	8	hSpCas9	negative selection	11261270
127653766	127653789	9	+	28162770	OCIAML5	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.1479568048498359	[150]	[245]	-1	hSpCas9	negative selection	11261271
127668083	127668106	9	+	28162770	OCIAML5	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	-0.3331932606006133	[66]	[95]	-2	hSpCas9	negative selection	11261272
127676633	127676656	9	+	28162770	OCIAML5	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-0.0289443329480763	[12]	[22]	0	hSpCas9	negative selection	11261273
127678483	127678506	9	+	28162770	OCIAML5	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-1.5525062890050894	[25]	[15]	-7	hSpCas9	negative selection	11261274
127678511	127678534	9	+	28162770	OCIAML5	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.2542800297852572	[223]	[338]	-2	hSpCas9	negative selection	11261275
127680212	127680235	9	-	28162770	OCIAML5	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.852066570863997	[155]	[77]	-7	hSpCas9	negative selection	11261276
127682437	127682460	9	+	28162770	OCIAML5	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	0.7025222808136403	[79]	[234]	6	hSpCas9	negative selection	11261277
127682463	127682486	9	-	28162770	OCIAML5	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-2.437029071585153	[20]	[6]	-8	hSpCas9	negative selection	11261278
127668158	127668181	9	+	28162770	EOL1	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.6317391010660656	[796]	[270]	-4	hSpCas9	negative selection	11430635
127658409	127658432	9	-	28162770	EOL1	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	0.7658500255514764	[47]	[42]	6	hSpCas9	negative selection	11430636
127653766	127653789	9	+	28162770	EOL1	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.3487367309570166	[451]	[186]	-3	hSpCas9	negative selection	11430637
127668083	127668106	9	+	28162770	EOL1	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.6875085742696851	[164]	[139]	6	hSpCas9	negative selection	11430638
127676633	127676656	9	+	28162770	EOL1	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.18758217740432848	[24]	[14]	1	hSpCas9	negative selection	11430639
127678483	127678506	9	+	28162770	EOL1	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.8024337340230496	[95]	[28]	-5	hSpCas9	negative selection	11430640
127678511	127678534	9	+	28162770	EOL1	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.32098998641377435	[376]	[158]	-2	hSpCas9	negative selection	11430641
127680212	127680235	9	-	28162770	EOL1	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.6604147291506217	[275]	[45]	-8	hSpCas9	negative selection	11430642
127682437	127682460	9	+	28162770	EOL1	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	0.09281925416033332	[193]	[108]	0	hSpCas9	negative selection	11430643
127682463	127682486	9	-	28162770	EOL1	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-3.5990141844864785	[68]	[2]	-9	hSpCas9	negative selection	11430644
127668158	127668181	9	+	28162770	MOLM13	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	0.25172891391964547	[538]	[463]	1	hSpCas9	negative selection	11600001
127658409	127658432	9	-	28162770	MOLM13	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	-1.7731187179592163	[51]	[10]	-7	hSpCas9	negative selection	11600002
127653766	127653789	9	+	28162770	MOLM13	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.8554936507003105	[291]	[381]	6	hSpCas9	negative selection	11600003
127668083	127668106	9	+	28162770	MOLM13	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	-0.4610275203939389	[98]	[51]	-3	hSpCas9	negative selection	11600004
127676633	127676656	9	+	28162770	MOLM13	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.31116387785712574	[67]	[60]	2	hSpCas9	negative selection	11600005
127678483	127678506	9	+	28162770	MOLM13	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.7708974780425377	[58]	[24]	-4	hSpCas9	negative selection	11600006
127678511	127678534	9	+	28162770	MOLM13	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-2.0194623225501553	[599]	[106]	-7	hSpCas9	negative selection	11600007
127680212	127680235	9	-	28162770	MOLM13	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-4.833280153175986	[275]	[6]	-9	hSpCas9	negative selection	11600008
127682437	127682460	9	+	28162770	MOLM13	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.4314166188359482	[165]	[88]	-3	hSpCas9	negative selection	11600009
127682463	127682486	9	-	28162770	MOLM13	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-1.5321106184554214	[71]	[17]	-6	hSpCas9	negative selection	11600010
127668158	127668181	9	+	28162770	HEL	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.7562302986508335	[624]	[236]	-5	hSpCas9	negative selection	11769367
127658409	127658432	9	-	28162770	HEL	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	1.5647363199990838	[37]	[71]	9	hSpCas9	negative selection	11769368
127653766	127653789	9	+	28162770	HEL	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.3017019141652901	[284]	[224]	2	hSpCas9	negative selection	11769369
127668083	127668106	9	+	28162770	HEL	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	1.3697203375939409	[86]	[143]	9	hSpCas9	negative selection	11769370
127676633	127676656	9	+	28162770	HEL	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-0.04175934227171352	[44]	[27]	0	hSpCas9	negative selection	11769371
127678483	127678506	9	+	28162770	HEL	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	1.6042646841857213	[56]	[110]	9	hSpCas9	negative selection	11769372
127678511	127678534	9	+	28162770	HEL	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.4688731586175541	[496]	[229]	-3	hSpCas9	negative selection	11769373
127680212	127680235	9	-	28162770	HEL	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-3.6791892628870055	[239]	[11]	-9	hSpCas9	negative selection	11769374
127682437	127682460	9	+	28162770	HEL	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-1.002166209177081	[171]	[54]	-6	hSpCas9	negative selection	11769375
127682463	127682486	9	-	28162770	HEL	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	0.4251473969277302	[49]	[42]	3	hSpCas9	negative selection	11769376
127668158	127668181	9	+	28162770	MV411	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.23550401299787205	[463]	[331]	-2	hSpCas9	negative selection	11938733
127658409	127658432	9	-	28162770	MV411	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	1.1349628215243626	[19]	[36]	8	hSpCas9	negative selection	11938734
127653766	127653789	9	+	28162770	MV411	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.13253545596997288	[208]	[192]	1	hSpCas9	negative selection	11938735
127668083	127668106	9	+	28162770	MV411	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.5858537684587068	[86]	[109]	5	hSpCas9	negative selection	11938736
127676633	127676656	9	+	28162770	MV411	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	1.4698299721192234	[17]	[41]	9	hSpCas9	negative selection	11938737
127678483	127678506	9	+	28162770	MV411	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.782309792611277	[48]	[23]	-5	hSpCas9	negative selection	11938738
127678511	127678534	9	+	28162770	MV411	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.3967085988041784	[310]	[198]	-3	hSpCas9	negative selection	11938739
127680212	127680235	9	-	28162770	MV411	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-0.5166332735460287	[196]	[115]	-4	hSpCas9	negative selection	11938740
127682437	127682460	9	+	28162770	MV411	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	0.5945362214050436	[124]	[158]	5	hSpCas9	negative selection	11938741
127682463	127682486	9	-	28162770	MV411	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	0.006429451278980425	[77]	[65]	0	hSpCas9	negative selection	11938742
127668158	127668181	9	+	28162770	MONOMAC1	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	0.5283871252239614	[250]	[414]	5	hSpCas9	negative selection	12108099
127658409	127658432	9	-	28162770	MONOMAC1	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	4.436288675223001	[10]	[272]	9	hSpCas9	negative selection	12108100
127653766	127653789	9	+	28162770	MONOMAC1	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.14779332803970427	[143]	[148]	-1	hSpCas9	negative selection	12108101
127668083	127668106	9	+	28162770	MONOMAC1	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.5805707316039985	[34]	[59]	5	hSpCas9	negative selection	12108102
127676633	127676656	9	+	28162770	MONOMAC1	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	0.5399287471066527	[11]	[19]	5	hSpCas9	negative selection	12108103
127678483	127678506	9	+	28162770	MONOMAC1	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.010623722828672744	[28]	[32]	0	hSpCas9	negative selection	12108104
127678511	127678534	9	+	28162770	MONOMAC1	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.033256585838150055	[182]	[204]	0	hSpCas9	negative selection	12108105
127680212	127680235	9	-	28162770	MONOMAC1	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-0.6602834393810173	[141]	[102]	-5	hSpCas9	negative selection	12108106
127682437	127682460	9	+	28162770	MONOMAC1	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.22840101796888873	[92]	[90]	-2	hSpCas9	negative selection	12108107
127682463	127682486	9	-	28162770	MONOMAC1	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	1.6960479490239342	[13]	[51]	9	hSpCas9	negative selection	12108108
127668158	127668181	9	+	28162770	OCIAML2	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	-0.006226248642337895	[78]	[435]	0	hSpCas9	negative selection	12277465
127658409	127658432	9	-	28162770	OCIAML2	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	-0.1201325781580278	[9]	[50]	-1	hSpCas9	negative selection	12277466
127653766	127653789	9	+	28162770	OCIAML2	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	0.16744401193855757	[39]	[248]	1	hSpCas9	negative selection	12277467
127668083	127668106	9	+	28162770	OCIAML2	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	0.21386834902990937	[20]	[134]	2	hSpCas9	negative selection	12277468
127676633	127676656	9	+	28162770	OCIAML2	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-0.3831669839918219	[3]	[16]	-3	hSpCas9	negative selection	12277469
127678483	127678506	9	+	28162770	OCIAML2	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-0.4262357058837076	[7]	[32]	-3	hSpCas9	negative selection	12277470
127678511	127678534	9	+	28162770	OCIAML2	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	0.25266083202696854	[52]	[349]	2	hSpCas9	negative selection	12277471
127680212	127680235	9	-	28162770	OCIAML2	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-1.3857409276556483	[32]	[69]	-7	hSpCas9	negative selection	12277472
127682437	127682460	9	+	28162770	OCIAML2	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	-0.8856673245210048	[20]	[62]	-6	hSpCas9	negative selection	12277473
127682463	127682486	9	-	28162770	OCIAML2	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	0.921687597536599	[7]	[83]	8	hSpCas9	negative selection	12277474
127668158	127668181	9	+	28162770	OCIAML3	viability	GCGCCACAAGCACATCGCAGAGG	STXBP1	ENSG00000136854	0.22170106906332165	[122]	[432]	2	hSpCas9	negative selection	12446831
127658409	127658432	9	-	28162770	OCIAML3	viability	GATACACAGCCTCCAGGCTGGGG	STXBP1	ENSG00000136854	-0.7460107337692135	[9]	[17]	-5	hSpCas9	negative selection	12446832
127653766	127653789	9	+	28162770	OCIAML3	viability	ATGACAGACATCATGACCGAGGG	STXBP1	ENSG00000136854	-0.4694625423858597	[60]	[132]	-4	hSpCas9	negative selection	12446833
127668083	127668106	9	+	28162770	OCIAML3	viability	TGAGACCAGCGGCATCGGGGAGG	STXBP1	ENSG00000136854	-0.26058390659897146	[24]	[62]	-2	hSpCas9	negative selection	12446834
127676633	127676656	9	+	28162770	OCIAML3	viability	TGTGCCCTCAGGCATCACGGAGG	STXBP1	ENSG00000136854	-3.5940076403241634	[11]	[2]	-9	hSpCas9	negative selection	12446835
127678483	127678506	9	+	28162770	OCIAML3	viability	AGACCTACCAGCTCTCACGGTGG	STXBP1	ENSG00000136854	-1.7639326417664756	[8]	[7]	-8	hSpCas9	negative selection	12446836
127678511	127678534	9	+	28162770	OCIAML3	viability	GATTATCAAGGACATCATGGAGG	STXBP1	ENSG00000136854	-0.039418788646525815	[95]	[281]	0	hSpCas9	negative selection	12446837
127680212	127680235	9	-	28162770	OCIAML3	viability	GGTGGTGCTGAAGGAGGCAGAGG	STXBP1	ENSG00000136854	-2.0185054688520734	[50]	[37]	-8	hSpCas9	negative selection	12446838
127682437	127682460	9	+	28162770	OCIAML3	viability	GCCCCAGGCGAGTACCGCAGTGG	STXBP1	ENSG00000136854	0.9836500597737596	[32]	[196]	8	hSpCas9	negative selection	12446839
127682463	127682486	9	-	28162770	OCIAML3	viability	CAAGGATGAAAATGATGAGGCGG	STXBP1	ENSG00000136854	-0.057954740083953515	[19]	[57]	0	hSpCas9	negative selection	12446840