Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 258010
• Symbol: SVIP
• Description: small VCP interacting protein

DataSource: http://genomecrispr.dkfz.de/#!/results/SVIP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
22827847	22827870	11	-	26472758	Jiyoye	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.28625059924626706	[198]	[182]	2	hSpCas9	negative selection	159360
22827205	22827228	11	+	26472758	Jiyoye	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.8187069372831817	[102]	[136]	6	hSpCas9	negative selection	159361
22827309	22827332	11	-	26472758	Jiyoye	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.2537009008441554	[217]	[195]	2	hSpCas9	negative selection	159362
22827207	22827230	11	-	26472758	Jiyoye	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.014121108244652791	[153]	[114]	0	hSpCas9	negative selection	159363
22827847	22827870	11	-	26472758	KBM7	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.2263004153963317	[601,623]	[237,256]	-2	hSpCas9	negative selection	350478
22827205	22827228	11	+	26472758	KBM7	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.1167304223438202	[412,323]	[224,151]	1	hSpCas9	negative selection	350479
22827309	22827332	11	-	26472758	KBM7	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.5651022278070345	[871,986]	[505,785]	6	hSpCas9	negative selection	350480
22827207	22827230	11	-	26472758	KBM7	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.6774362719031398	[769,895]	[628,638]	7	hSpCas9	negative selection	350481
22827847	22827870	11	-	26472758	Raji	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.14952476766335265	[281]	[58]	-1	hSpCas9	negative selection	541596
22827205	22827228	11	+	26472758	Raji	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	1.5098209978728099	[114]	[75]	9	hSpCas9	negative selection	541597
22827309	22827332	11	-	26472758	Raji	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.5033122117047386	[455]	[149]	5	hSpCas9	negative selection	541598
22827207	22827230	11	-	26472758	Raji	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.851043782113814	[429]	[179]	7	hSpCas9	negative selection	541599
22827847	22827870	11	-	26472758	K562	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.1676219784105707	[597]	[566]	1	hSpCas9	negative selection	732714
22827205	22827228	11	+	26472758	K562	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.3508267463165702	[351]	[232]	-2	hSpCas9	negative selection	732715
22827309	22827332	11	-	26472758	K562	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.9828191255718891	[602]	[1005]	8	hSpCas9	negative selection	732716
22827207	22827230	11	-	26472758	K562	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.7450527095383311	[727]	[1029]	6	hSpCas9	negative selection	732717
22827847	22827870	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.29455121686358315	[3,2]	[2,0]	-4	hSpCas9	positive selection	3024806
22827823	22827846	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.473050730953095	[4,4]	[4,0]	-6	hSpCas9	positive selection	3024807
22827847	22827870	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.6201091986084293	[3,3]	[3,3]	8	hSpCas9	positive selection	3092664
22827823	22827846	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.14470284593318722	[4,4]	[4,2]	2	hSpCas9	positive selection	3092665
22827202	22827225		+	24336571	A375	resistance to PLX after 7 days	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	-0.11614116974050115	[14,20]	[17,14]	-4	hSpCas9	positive selection	3148467
22827232	22827255		-	24336571	A375	resistance to PLX after 7 days	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	-0.2807985879243579	[17,14]	[11,14]	-8	hSpCas9	positive selection	3148468
22827202	22827225		+	24336571	A375	resistance to PLX after 14 days	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	-0.6526910314950126	[11,36]	[7,5]	-7	hSpCas9	positive selection	3206260
22827232	22827255		-	24336571	A375	resistance to PLX after 14 days	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	0.11258296437060694	[17,17]	[7,8]	1	hSpCas9	positive selection	3206261
22827202	22827225		+	24336571	A375	viability after 7 days	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.07149554539017061	[17]	[14,20]	1	hSpCas9	negative selection	3264053
22827232	22827255		-	24336571	A375	viability after 7 days	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	-0.23822688523135116	[20]	[17,14]	-3	hSpCas9	negative selection	3264054
22827202	22827225		+	24336571	A375	viability after 14 days	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5357000309339328	[17]	[11,36]	6	hSpCas9	negative selection	3321846
22827232	22827255		-	24336571	A375	viability after 14 days	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	-0.1334573761887234	[20]	[17,17]	-1	hSpCas9	negative selection	3321847
22827207	22827230	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.38696149186243056	[116,116]	[0,0]	2	hSpCas9	positive selection	3395774
22827847	22827870	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3395775
22827823	22827846	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	1.5849008694743394	[203,203]	[3,3]	6	hSpCas9	positive selection	3395776
22827847	22827870	11	-	26780180	HT29	viability (Avana library 4 designs)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.568427697879693	[]	[]	2	hSpCas9	negative selection	3463513
22827823	22827846	11	-	26780180	HT29	viability (Avana library 4 designs)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.766724366161199	[]	[]	3	hSpCas9	negative selection	3463514
22827847	22827870	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.122697974956092	[]	[]	0	hSpCas9	negative selection	3565590
22827823	22827846	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.337280726988586	[]	[]	0	hSpCas9	negative selection	3565591
22827847	22827870	11	-	26780180	A375	viability (Avana lentiGuide)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-2.97841852609856	[]	[]	-5	hSpCas9	negative selection	3674249
22827823	22827846	11	-	26780180	A375	viability (Avana lentiGuide)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-1.50854918669837	[]	[]	-2	hSpCas9	negative selection	3674250
22827847	22827870	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.07128764907084131	[5]	[4,4]	-1	hSpCas9	positive selection	3782856
22827823	22827846	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.3344784402965758	[5]	[4,2]	-5	hSpCas9	positive selection	3782857
22827847	22827870	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.03685658361487806	[4]	[2,4]	0	hSpCas9	positive selection	3891463
22827823	22827846	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.420275368872401	[5]	[6,6]	9	hSpCas9	positive selection	3891464
22827207	22827230	11	-	26780180	A375	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	1.04281969642113	[]	[]	5	hSpCas9	negative selection	4001121
22827202	22827225	11	+	26780180	A375	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.539400762660059	[]	[]	1	hSpCas9	negative selection	4001122
22827847	22827870	11	-	26780180	A375	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.965230213470541	[]	[]	4	hSpCas9	negative selection	4001123
22827823	22827846	11	-	26780180	A375	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	1.05239089399255	[]	[]	5	hSpCas9	negative selection	4001124
22827207	22827230	11	-	26780180	HT29	viability (GeCKOv2 library)	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.916911039183549	[]	[]	4	hSpCas9	negative selection	4109087
22827202	22827225	11	+	26780180	HT29	viability (GeCKOv2 library)	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.586043361876972	[]	[]	2	hSpCas9	negative selection	4109088
22827847	22827870	11	-	26780180	HT29	viability (GeCKOv2 library)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	1.15199782146127	[]	[]	5	hSpCas9	negative selection	4109089
22827823	22827846	11	-	26780180	HT29	viability (GeCKOv2 library)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.922729618622994	[]	[]	4	hSpCas9	negative selection	4109090
22827202	22827225	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.11968010750288037	[4]	[3,2]	3	hSpCas9	positive selection	4174725
22827232	22827255	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	0.0944097131494064	[3]	[2,3]	2	hSpCas9	positive selection	4174726
22827202	22827225	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	1.1909996013045707	[4]	[3,2,3,4]	8	hSpCas9	positive selection	4238747
22827232	22827255	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAAAACAAATTGCTACATCCGG	SVIP	ENSG00000198168	0.15630032198708876	[4]	[3,4,2,0]	1	hSpCas9	positive selection	4238748
22827202	22827225	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.46317846455862494	[3]	[3,3]	8	hSpCas9	positive selection	4301514
22827207	22827230	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.034354680309987604	[2]	[3,1]	0	hSpCas9	positive selection	4365768
22827847	22827870	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.49278470623995174	[1]	[1,0]	-8	hSpCas9	positive selection	4365769
22827823	22827846	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.28200634129118346	[3]	[3,3]	5	hSpCas9	positive selection	4365770
22827263	22827285	11	-	27760321	OCIAML3	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-0.948255138094841	[2,1]	[0,0]	-7	hSpCas9	negative selection	4444566
22827308	22827330	11	-	27760321	OCIAML3	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	0.6866055555743912	[732,729]	[703,1209]	7	hSpCas9	negative selection	4444567
22827823	22827845	11	-	27760321	OCIAML3	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4444568
22827263	22827285	11	-	27760321	OCIAML2	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-0.9970005033598897	[2,1]	[0,0]	-7	hSpCas9	negative selection	4528029
22827308	22827330	11	-	27760321	OCIAML2	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.035896864320167254	[732,729]	[493,690]	0	hSpCas9	negative selection	4528030
22827823	22827845	11	-	27760321	OCIAML2	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4528031
22827263	22827285	11	-	27760321	MV411	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-0.703176569180159	[2,1]	[0,0]	-5	hSpCas9	negative selection	4611492
22827308	22827330	11	-	27760321	MV411	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	0.5969377089189479	[732,729]	[715,756]	4	hSpCas9	negative selection	4611493
22827823	22827845	11	-	27760321	MV411	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4611494
22827263	22827285	11	-	27760321	HL60	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-1.0110467309742956	[2,1]	[0,0]	-7	hSpCas9	negative selection	4694955
22827308	22827330	11	-	27760321	HL60	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	0.11498792335796204	[732,729]	[603,696]	1	hSpCas9	negative selection	4694956
22827823	22827845	11	-	27760321	HL60	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4694957
22827263	22827285	11	-	27760321	HT1080	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	0.30562769391905587	[1,1]	[0,0]	1	hSpCas9	negative selection	4778418
22827308	22827330	11	-	27760321	HT1080	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	1.0029159023866698	[729,569]	[580,450]	5	hSpCas9	negative selection	4778419
22827823	22827845	11	-	27760321	HT1080	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4778420
22827263	22827285	11	-	27760321	HT29	viability after 7 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-1.3840325596302083	[1,1]	[0,0,0]	-9	hSpCas9	negative selection	4861881
22827308	22827330	11	-	27760321	HT29	viability after 7 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.43809738403443116	[729,569]	[724,614,527]	-6	hSpCas9	negative selection	4861882
22827823	22827845	11	-	27760321	HT29	viability after 7 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4861883
22827263	22827285	11	-	27760321	HT29	viability after 25 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-1.214054570927468	[1,1]	[0,0,0]	-7	hSpCas9	negative selection	4945344
22827308	22827330	11	-	27760321	HT29	viability after 25 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	0.10996644243860998	[729,569]	[732,788,895]	1	hSpCas9	negative selection	4945345
22827823	22827845	11	-	27760321	HT29	viability after 25 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4945346
22827263	22827285	11	-	27760321	HT29	viability after 22 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	1.6597128388931823	[1,1]	[15,0,4]	9	hSpCas9	negative selection	5028807
22827308	22827330	11	-	27760321	HT29	viability after 22 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.010974494775565447	[729,569]	[509,738,996]	0	hSpCas9	negative selection	5028808
22827823	22827845	11	-	27760321	HT29	viability after 22 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5028809
22827263	22827285	11	-	27760321	HT29	viability after 19 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	0.6899379208368517	[1,1]	[9,0,0]	7	hSpCas9	negative selection	5112270
22827308	22827330	11	-	27760321	HT29	viability after 19 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.15533795599506894	[729,569]	[668,443,880]	-1	hSpCas9	negative selection	5112271
22827823	22827845	11	-	27760321	HT29	viability after 19 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5112272
22827263	22827285	11	-	27760321	HT29	viability after 16 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	1.8885793975947571	[1,1]	[24,0,0]	9	hSpCas9	negative selection	5195733
22827308	22827330	11	-	27760321	HT29	viability after 16 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.22130927144458334	[729,569]	[719,525,636]	-2	hSpCas9	negative selection	5195734
22827823	22827845	11	-	27760321	HT29	viability after 16 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5195735
22827263	22827285	11	-	27760321	HT29	viability after 13 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-0.8069927323353898	[1,1]	[0,0,1]	-7	hSpCas9	negative selection	5279196
22827308	22827330	11	-	27760321	HT29	viability after 13 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.26915752992473596	[729,569]	[672,543,657]	-3	hSpCas9	negative selection	5279197
22827823	22827845	11	-	27760321	HT29	viability after 13 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5279198
22827263	22827285	11	-	27760321	HT29	viability after 10 days	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	-1.3423674045470744	[1,1]	[0,0,0]	-8	hSpCas9	negative selection	5362659
22827308	22827330	11	-	27760321	HT29	viability after 10 days	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	-0.16126712516851138	[729,569]	[537,746,888]	-2	hSpCas9	negative selection	5362660
22827823	22827845	11	-	27760321	HT29	viability after 10 days	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5362661
22827263	22827285	11	-	27760321	MOLM13	viability	CAAGAAAAGAGAAAGAAAAAGG	SVIP	ENSG00000198168	1.7802302168496897	[2,1]	[0,7]	9	hSpCas9	negative selection	5446122
22827308	22827330	11	-	27760321	MOLM13	viability	TTCTTCAAGGCTGCATCTCGGG	SVIP	ENSG00000198168	0.6776976508397544	[732,729]	[934,429]	5	hSpCas9	negative selection	5446123
22827823	22827845	11	-	27760321	MOLM13	viability	GCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5446124
22827202	22827225	11	+	27260156	BXPC3	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.42762449744638154	[558]	[644,722,926,876]	8	hSpCas9	negative selection	5573974
22827207	22827230	11	-	27260156	BXPC3	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.1521698572424007	[361]	[323,427,438,509]	3	hSpCas9	negative selection	5638228
22827847	22827870	11	-	27260156	BXPC3	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.32476605117590496	[153]	[105,102,149,162]	-6	hSpCas9	negative selection	5638229
22827823	22827846	11	-	27260156	BXPC3	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.3272462795209022	[623]	[784,682,966,851]	7	hSpCas9	negative selection	5638230
22827202	22827225	11	+	27260156	A673	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.3449161964633244	[558]	[941,730,900,846]	7	hSpCas9	negative selection	5695225
22827207	22827230	11	-	27260156	A673	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.12490543735975812	[361]	[521,437,532,403]	3	hSpCas9	negative selection	5759479
22827847	22827870	11	-	27260156	A673	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.15178081256229436	[153]	[231,227,146,217]	3	hSpCas9	negative selection	5759480
22827823	22827846	11	-	27260156	A673	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.13761471385541596	[623]	[902,821,800,775]	3	hSpCas9	negative selection	5759481
22827202	22827225	11	+	27260156	A375	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5265077358523643	[558]	[842,1190,897,868]	7	hSpCas9	negative selection	5816476
22827207	22827230	11	-	27260156	A375	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.054407808977621874	[361]	[478,487,293,380]	-1	hSpCas9	negative selection	5880730
22827847	22827870	11	-	27260156	A375	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.014035148962416422	[153]	[228,166,185,133]	0	hSpCas9	negative selection	5880731
22827823	22827846	11	-	27260156	A375	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.12666845803288046	[623]	[956,995,563,702]	1	hSpCas9	negative selection	5880732
22827202	22827225	11	+	27260156	COLO741	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.4608028260137955	[558]	[1238,759,969]	8	hSpCas9	negative selection	5937727
22827207	22827230	11	-	27260156	COLO741	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.3642867063055189	[361]	[651,534,601]	7	hSpCas9	negative selection	6001981
22827847	22827870	11	-	27260156	COLO741	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.09154038191840419	[153]	[241,126,188]	-2	hSpCas9	negative selection	6001982
22827823	22827846	11	-	27260156	COLO741	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.2822418502206336	[623]	[1071,956,891]	6	hSpCas9	negative selection	6001983
22827202	22827225	11	+	27260156	CAL120	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.43669328594180246	[558]	[889,1018,907]	6	hSpCas9	negative selection	6058978
22827207	22827230	11	-	27260156	CAL120	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5947332820405844	[361]	[643,758,632]	8	hSpCas9	negative selection	6123232
22827847	22827870	11	-	27260156	CAL120	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.02441379914939512	[153]	[155,142,259]	0	hSpCas9	negative selection	6123233
22827823	22827846	11	-	27260156	CAL120	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.0638961035601816	[623]	[867,686,692]	-1	hSpCas9	negative selection	6123234
22827202	22827225	11	+	27260156	CADOES1	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.4690451507042196	[558]	[640,858,737,637]	7	hSpCas9	negative selection	6180229
22827207	22827230	11	-	27260156	CADOES1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5638360581977324	[361]	[546,406,395,645]	8	hSpCas9	negative selection	6244483
22827847	22827870	11	-	27260156	CADOES1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.3270224062391607	[153]	[71,49,211,122]	-5	hSpCas9	negative selection	6244484
22827823	22827846	11	-	27260156	CADOES1	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.1250571721080042	[623]	[646,622,515,749]	2	hSpCas9	negative selection	6244485
22827202	22827225	11	+	27260156	EWS502	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.41465303313811486	[558]	[653,861,787,868]	7	hSpCas9	negative selection	6301480
22827207	22827230	11	-	27260156	EWS502	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.6672345512169373	[361]	[372,720,535,842]	9	hSpCas9	negative selection	6365734
22827847	22827870	11	-	27260156	EWS502	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.22781064323580869	[153]	[151,128,141,131]	-4	hSpCas9	negative selection	6365735
22827823	22827846	11	-	27260156	EWS502	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.032009500940450075	[623]	[570,707,708,727]	0	hSpCas9	negative selection	6365736
22827202	22827225	11	+	27260156	EW8	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5984113436856949	[558]	[744,697,531,798]	9	hSpCas9	negative selection	6422731
22827207	22827230	11	-	27260156	EW8	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.39871919541182305	[361]	[382,414,282,481]	7	hSpCas9	negative selection	6486985
22827847	22827870	11	-	27260156	EW8	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.30505040710217735	[153]	[226,145,120,135]	5	hSpCas9	negative selection	6486986
22827823	22827846	11	-	27260156	EW8	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.12139441269946277	[623]	[601,747,400,479]	2	hSpCas9	negative selection	6486987
22827202	22827225	11	+	27260156	CORL105	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.523958610673696	[558]	[953,833,1123,882]	8	hSpCas9	negative selection	6543982
22827207	22827230	11	-	27260156	CORL105	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.03232657112024995	[361]	[289,478,550,425]	0	hSpCas9	negative selection	6608236
22827847	22827870	11	-	27260156	CORL105	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.08744193906538911	[153]	[217,135,278,148]	1	hSpCas9	negative selection	6608237
22827823	22827846	11	-	27260156	CORL105	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.017952283960207316	[623]	[855,777,806,531]	0	hSpCas9	negative selection	6608238
22827202	22827225	11	+	27260156	HS294T	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.3807273373267722	[558]	[330,284,265,228]	5	hSpCas9	negative selection	6665233
22827207	22827230	11	-	27260156	HS294T	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.06921406408836028	[361]	[107,205,130,142]	0	hSpCas9	negative selection	6729487
22827847	22827870	11	-	27260156	HS294T	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.1638334687798897	[153]	[58,28,59,66]	-2	hSpCas9	negative selection	6729488
22827823	22827846	11	-	27260156	HS294T	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.4618253008579001	[623]	[198,153,167,177]	-6	hSpCas9	negative selection	6729489
22827202	22827225	11	+	27260156	HCC44	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.553261329718236	[558]	[1157,711,1182,751]	8	hSpCas9	negative selection	6786484
22827207	22827230	11	-	27260156	HCC44	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.44330176548828654	[361]	[757,352,610,556]	7	hSpCas9	negative selection	6850738
22827847	22827870	11	-	27260156	HCC44	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.3262088586779446	[153]	[107,78,142,227]	-5	hSpCas9	negative selection	6850739
22827823	22827846	11	-	27260156	HCC44	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.15738377676533083	[623]	[883,545,815,938]	2	hSpCas9	negative selection	6850740
22827202	22827225	11	+	27260156	G402	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.36589683088253167	[558]	[1388,733,918,551]	4	hSpCas9	negative selection	6907735
22827207	22827230	11	-	27260156	G402	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.08930134420441843	[361]	[372,579,653,272]	1	hSpCas9	negative selection	6971989
22827847	22827870	11	-	27260156	G402	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.8039410036318444	[153]	[84,71,164,102]	-7	hSpCas9	negative selection	6971990
22827823	22827846	11	-	27260156	G402	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.2842413675239797	[623]	[1351,854,555,995]	3	hSpCas9	negative selection	6971991
22827202	22827225	11	+	27260156	L33	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.3435151922241112	[558]	[650,277,490,727]	7	hSpCas9	negative selection	7028986
22827207	22827230	11	-	27260156	L33	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.18614833180770152	[361]	[406,141,204,191]	-4	hSpCas9	negative selection	7093240
22827847	22827870	11	-	27260156	L33	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.13410738592813543	[153]	[162,36,126,105]	-3	hSpCas9	negative selection	7093241
22827823	22827846	11	-	27260156	L33	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.13123096744359752	[623]	[491,195,354,743]	-3	hSpCas9	negative selection	7093242
22827202	22827225	11	+	27260156	K562	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.31031419705324115	[558]	[648,740,459,616]	4	hSpCas9	negative selection	7150237
22827207	22827230	11	-	27260156	K562	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5756255768786223	[361]	[436,511,536,430]	7	hSpCas9	negative selection	7214491
22827847	22827870	11	-	27260156	K562	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.05084483706742371	[153]	[141,243,155,40]	0	hSpCas9	negative selection	7214492
22827823	22827846	11	-	27260156	K562	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.2475382921747437	[623]	[501,892,597,635]	3	hSpCas9	negative selection	7214493
22827202	22827225	11	+	27260156	HT29	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.6149573540257651	[558]	[1147,1277,969,815]	9	hSpCas9	negative selection	7271488
22827207	22827230	11	-	27260156	HT29	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.16266807292002547	[361]	[569,716,302,411]	3	hSpCas9	negative selection	7335742
22827847	22827870	11	-	27260156	HT29	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.3326571192651606	[153]	[166,175,129,126]	-6	hSpCas9	negative selection	7335743
22827823	22827846	11	-	27260156	HT29	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.12616096275397853	[623]	[1245,681,613,787]	2	hSpCas9	negative selection	7335744
22827202	22827225	11	+	27260156	MHHES1	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5568807888754742	[558]	[1091,1130,660,854]	8	hSpCas9	negative selection	7392739
22827207	22827230	11	-	27260156	MHHES1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.06919848544142682	[361]	[611,540,349,268]	1	hSpCas9	negative selection	7456993
22827847	22827870	11	-	27260156	MHHES1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.15390445805535524	[153]	[73,190,213,138]	-3	hSpCas9	negative selection	7456994
22827823	22827846	11	-	27260156	MHHES1	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.03763044150553607	[623]	[829,1023,461,500]	0	hSpCas9	negative selection	7456995
22827202	22827225	11	+	27260156	MEWO	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.11805160274344029	[558]	[619,515,576]	2	hSpCas9	negative selection	7513990
22827207	22827230	11	-	27260156	MEWO	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.44416704749499664	[361]	[598,460,348]	8	hSpCas9	negative selection	7578244
22827847	22827870	11	-	27260156	MEWO	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.1746256283754546	[153]	[147,157,178]	4	hSpCas9	negative selection	7578245
22827823	22827846	11	-	27260156	MEWO	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.06611097161776675	[623]	[734,477,644]	1	hSpCas9	negative selection	7578246
22827202	22827225	11	+	27260156	LNCAPCLONEFGC	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.4549704776598852	[558]	[614,681,664,811]	7	hSpCas9	negative selection	7635241
22827207	22827230	11	-	27260156	LNCAPCLONEFGC	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.18886344979594138	[361]	[360,396,389,347]	3	hSpCas9	negative selection	7699495
22827847	22827870	11	-	27260156	LNCAPCLONEFGC	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.5619693359285549	[153]	[45,97,96,137]	-7	hSpCas9	negative selection	7699496
22827823	22827846	11	-	27260156	LNCAPCLONEFGC	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.1405568020627872	[623]	[506,428,610,523]	-2	hSpCas9	negative selection	7699497
22827202	22827225	11	+	27260156	PANC0327	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.4046111182282788	[558]	[773,629,564,672]	6	hSpCas9	negative selection	7756492
22827207	22827230	11	-	27260156	PANC0327	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.6066133156980396	[361]	[411,302,501,758]	8	hSpCas9	negative selection	7820746
22827847	22827870	11	-	27260156	PANC0327	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.5306968557140903	[153]	[51,43,207,77]	-6	hSpCas9	negative selection	7820747
22827823	22827846	11	-	27260156	PANC0327	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.28258187470175306	[623]	[340,487,1043,820]	4	hSpCas9	negative selection	7820748
22827202	22827225	11	+	27260156	NCIH2009	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5414162880959894	[558]	[1045,871,1476]	7	hSpCas9	negative selection	7877743
22827207	22827230	11	-	27260156	NCIH2009	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.021780006625251647	[361]	[463,661,357]	0	hSpCas9	negative selection	7941997
22827847	22827870	11	-	27260156	NCIH2009	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.09873809081634133	[153]	[264,206,142]	-1	hSpCas9	negative selection	7941998
22827823	22827846	11	-	27260156	NCIH2009	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.3383000599173722	[623]	[737,753,583]	-4	hSpCas9	negative selection	7941999
22827202	22827225	11	+	27260156	NCIH1373	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.8876281728293305	[558]	[936,1153,1053,386]	8	hSpCas9	negative selection	7998994
22827207	22827230	11	-	27260156	NCIH1373	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.14390993809484867	[361]	[326,242,596,166]	1	hSpCas9	negative selection	8063248
22827847	22827870	11	-	27260156	NCIH1373	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.5149366479672517	[153]	[189,14,155,37]	-5	hSpCas9	negative selection	8063249
22827823	22827846	11	-	27260156	NCIH1373	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.4860228756918821	[623]	[643,358,267,205]	-5	hSpCas9	negative selection	8063250
22827202	22827225	11	+	27260156	PATU8902	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.7424716413583393	[558]	[1649,1152,871,1675]	7	hSpCas9	negative selection	8120245
22827207	22827230	11	-	27260156	PATU8902	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5282915676201642	[361]	[882,833,557,661]	5	hSpCas9	negative selection	8184499
22827847	22827870	11	-	27260156	PATU8902	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.3305547318290456	[153]	[204,164,315,393]	3	hSpCas9	negative selection	8184500
22827823	22827846	11	-	27260156	PATU8902	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.4820826415374249	[623]	[1654,996,838,1476]	5	hSpCas9	negative selection	8184501
22827202	22827225	11	+	27260156	PANC1	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5511232461074418	[558]	[739,798,716,584]	8	hSpCas9	negative selection	8241496
22827207	22827230	11	-	27260156	PANC1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.2722700504140239	[361]	[387,319,438,342]	4	hSpCas9	negative selection	8305750
22827847	22827870	11	-	27260156	PANC1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.06561460035275513	[153]	[98,152,128,168]	1	hSpCas9	negative selection	8305751
22827823	22827846	11	-	27260156	PANC1	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.1900763627975734	[623]	[535,810,648,500]	3	hSpCas9	negative selection	8305752
22827202	22827225	11	+	27260156	PANC0813	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.47275604275929317	[558]	[969,626,1104,945]	7	hSpCas9	negative selection	8362747
22827207	22827230	11	-	27260156	PANC0813	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.25245061413302605	[361]	[635,587,455,364]	4	hSpCas9	negative selection	8427001
22827847	22827870	11	-	27260156	PANC0813	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.31140665144346813	[153]	[250,100,53,183]	-5	hSpCas9	negative selection	8427002
22827823	22827846	11	-	27260156	PANC0813	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.07216952277369837	[623]	[709,532,905,643]	-1	hSpCas9	negative selection	8427003
22827202	22827225	11	+	27260156	RDES	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.6418276054676353	[558]	[855,926,1155,1101]	9	hSpCas9	negative selection	8483998
22827207	22827230	11	-	27260156	RDES	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5694772317269454	[361]	[459,637,833,550]	8	hSpCas9	negative selection	8548252
22827847	22827870	11	-	27260156	RDES	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.2247946263968219	[153]	[137,178,321,204]	3	hSpCas9	negative selection	8548253
22827823	22827846	11	-	27260156	RDES	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.20530338821521404	[623]	[772,837,732,965]	3	hSpCas9	negative selection	8548254
22827202	22827225	11	+	27260156	PC3	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.11807279243991237	[558]	[506,455,687,782]	2	hSpCas9	negative selection	8605249
22827207	22827230	11	-	27260156	PC3	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.0796520239519074	[361]	[155,436,773,380]	1	hSpCas9	negative selection	8669503
22827847	22827870	11	-	27260156	PC3	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.3688120713822327	[153]	[29,131,368,72]	-7	hSpCas9	negative selection	8669504
22827823	22827846	11	-	27260156	PC3	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.012530340222042746	[623]	[375,697,1003,578]	0	hSpCas9	negative selection	8669505
22827202	22827225	11	+	27260156	PATU8988T	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.10308121663361214	[558]	[424,856,463,603]	1	hSpCas9	negative selection	8726500
22827207	22827230	11	-	27260156	PATU8988T	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.0831783018541109	[361]	[242,403,426,413]	1	hSpCas9	negative selection	8790754
22827847	22827870	11	-	27260156	PATU8988T	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.24911247413883353	[153]	[71,107,136,186]	-4	hSpCas9	negative selection	8790755
22827823	22827846	11	-	27260156	PATU8988T	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.08773781527592245	[623]	[279,879,567,570]	-1	hSpCas9	negative selection	8790756
22827202	22827225	11	+	27260156	T47D	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.4795840700326758	[558]	[950,807,925,956]	8	hSpCas9	negative selection	8847751
22827207	22827230	11	-	27260156	T47D	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.3789476398380676	[361]	[460,566,520,645]	7	hSpCas9	negative selection	8912005
22827847	22827870	11	-	27260156	T47D	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.2648259393881045	[153]	[192,135,100,169]	-5	hSpCas9	negative selection	8912006
22827823	22827846	11	-	27260156	T47D	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.1241690118211412	[623]	[774,705,791,906]	2	hSpCas9	negative selection	8912007
22827202	22827225	11	+	27260156	SU8686	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.379489310164002	[558]	[652,592,668,1037]	6	hSpCas9	negative selection	8969002
22827207	22827230	11	-	27260156	SU8686	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.3109128710703509	[361]	[318,332,543,645]	5	hSpCas9	negative selection	9033256
22827847	22827870	11	-	27260156	SU8686	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.0218997553477569	[153]	[174,102,137,216]	0	hSpCas9	negative selection	9033257
22827823	22827846	11	-	27260156	SU8686	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.18206753488045593	[623]	[613,536,454,564]	-3	hSpCas9	negative selection	9033258
22827202	22827225	11	+	27260156	SKES1	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.5687895257075191	[558]	[915,745,819,820]	9	hSpCas9	negative selection	9090253
22827207	22827230	11	-	27260156	SKES1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.31525314519733233	[361]	[439,373,370,581]	6	hSpCas9	negative selection	9154507
22827847	22827870	11	-	27260156	SKES1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.10692456096827896	[153]	[151,203,156,72]	-2	hSpCas9	negative selection	9154508
22827823	22827846	11	-	27260156	SKES1	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.011931221252751312	[623]	[806,680,464,588]	0	hSpCas9	negative selection	9154509
22827202	22827225	11	+	27260156	TOV112D	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.7282417455724544	[558]	[822,1030,976,894]	9	hSpCas9	negative selection	9211504
22827207	22827230	11	-	27260156	TOV112D	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.381535969181743	[361]	[405,444,509,513]	7	hSpCas9	negative selection	9275758
22827847	22827870	11	-	27260156	TOV112D	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.4882531487498032	[153]	[255,90,52,48]	-7	hSpCas9	negative selection	9275759
22827823	22827846	11	-	27260156	TOV112D	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.05476904027780988	[623]	[632,734,768,482]	1	hSpCas9	negative selection	9275760
22827202	22827225	11	+	27260156	TC71	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.39154205171177014	[558]	[701,928,708,809]	8	hSpCas9	negative selection	9332755
22827207	22827230	11	-	27260156	TC71	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.14735820318867365	[361]	[388,441,378,516]	3	hSpCas9	negative selection	9397009
22827847	22827870	11	-	27260156	TC71	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.05001641607885299	[153]	[101,201,177,204]	1	hSpCas9	negative selection	9397010
22827823	22827846	11	-	27260156	TC71	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	0.09244539581357875	[623]	[767,603,750,727]	2	hSpCas9	negative selection	9397011
22827202	22827225	11	+	27260156	TC32	viability	CTTACCCTAAGTCCACCTTCTGG	SVIP	ENSG00000198168	0.169392846330369	[558]	[579,288,914,726]	3	hSpCas9	negative selection	9454006
22827207	22827230	11	-	27260156	TC32	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.45405249766004613	[361]	[403,416,499,550]	7	hSpCas9	negative selection	9518260
22827847	22827870	11	-	27260156	TC32	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.019695760550465735	[153]	[139,186,95,110]	0	hSpCas9	negative selection	9518261
22827823	22827846	11	-	27260156	TC32	viability	TGCAGAGAGAAGACAAAAAGAGG	SVIP	ENSG00000198168	-0.16123583545122006	[623]	[470,386,712,590]	-3	hSpCas9	negative selection	9518262
22827847	22827870	11	-	28162770	P31FUJ	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.2653170363590203	[290]	[410]	3	hSpCas9	negative selection	10245797
22827205	22827228	11	+	28162770	P31FUJ	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.2219954494577957	[132]	[133]	-2	hSpCas9	negative selection	10245798
22827309	22827332	11	-	28162770	P31FUJ	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.44648767885493057	[443]	[710]	5	hSpCas9	negative selection	10245799
22827207	22827230	11	-	28162770	P31FUJ	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.7848276896074129	[487]	[987]	8	hSpCas9	negative selection	10245800
22827847	22827870	11	-	28162770	TF1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10415163
22827205	22827228	11	+	28162770	TF1	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10415164
22827309	22827332	11	-	28162770	TF1	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	NaN	[NaN]	[812]	1	hSpCas9	negative selection	10415165
22827207	22827230	11	-	28162770	TF1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	NaN	[NaN]	[434]	1	hSpCas9	negative selection	10415166
22827847	22827870	11	-	28162770	SKM1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.5033169860661311	[84]	[212]	5	hSpCas9	negative selection	10584529
22827205	22827228	11	+	28162770	SKM1	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.465979064942019	[42]	[104]	4	hSpCas9	negative selection	10584530
22827309	22827332	11	-	28162770	SKM1	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	-0.025164647878400892	[117]	[204]	0	hSpCas9	negative selection	10584531
22827207	22827230	11	-	28162770	SKM1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.4400134954480355	[117]	[282]	4	hSpCas9	negative selection	10584532
22827847	22827870	11	-	28162770	SKM1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.5033169860661311	[84]	[212]	5	hSpCas9	negative selection	10753895
22827205	22827228	11	+	28162770	SKM1	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.465979064942019	[42]	[104]	4	hSpCas9	negative selection	10753896
22827309	22827332	11	-	28162770	SKM1	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	-0.025164647878400892	[117]	[204]	0	hSpCas9	negative selection	10753897
22827207	22827230	11	-	28162770	SKM1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.4400134954480355	[117]	[282]	4	hSpCas9	negative selection	10753898
22827847	22827870	11	-	28162770	PL21	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.4449438786694069	[293]	[93]	-3	hSpCas9	negative selection	10923261
22827205	22827228	11	+	28162770	PL21	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.4711009360947429	[120]	[72]	4	hSpCas9	negative selection	10923262
22827309	22827332	11	-	28162770	PL21	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	-0.10520559620243797	[345]	[139]	0	hSpCas9	negative selection	10923263
22827207	22827230	11	-	28162770	PL21	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.04459397460152992	[281]	[118]	0	hSpCas9	negative selection	10923264
22827847	22827870	11	-	28162770	P31FUJ	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.2653170363590203	[290]	[410]	3	hSpCas9	negative selection	11092627
22827205	22827228	11	+	28162770	P31FUJ	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.2219954494577957	[132]	[133]	-2	hSpCas9	negative selection	11092628
22827309	22827332	11	-	28162770	P31FUJ	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.44648767885493057	[443]	[710]	5	hSpCas9	negative selection	11092629
22827207	22827230	11	-	28162770	P31FUJ	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.7848276896074129	[487]	[987]	8	hSpCas9	negative selection	11092630
22827847	22827870	11	-	28162770	OCIAML5	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.3266044730431332	[200]	[454]	2	hSpCas9	negative selection	11261993
22827205	22827228	11	+	28162770	OCIAML5	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.7000634774189471	[71]	[79]	-4	hSpCas9	negative selection	11261994
22827309	22827332	11	-	28162770	OCIAML5	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.9493877497539229	[244]	[853]	8	hSpCas9	negative selection	11261995
22827207	22827230	11	-	28162770	OCIAML5	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.29668087539993215	[243]	[540]	2	hSpCas9	negative selection	11261996
22827847	22827870	11	-	28162770	EOL1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	-0.3162338274161315	[578]	[244]	-2	hSpCas9	negative selection	11431359
22827205	22827228	11	+	28162770	EOL1	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.49416230795825467	[251]	[186]	4	hSpCas9	negative selection	11431360
22827309	22827332	11	-	28162770	EOL1	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.4933545039006497	[448]	[332]	4	hSpCas9	negative selection	11431361
22827207	22827230	11	-	28162770	EOL1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	-0.07924380759183963	[380]	[189]	0	hSpCas9	negative selection	11431362
22827847	22827870	11	-	28162770	MOLM13	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	1.2322054638557405	[417]	[709]	8	hSpCas9	negative selection	11600725
22827205	22827228	11	+	28162770	MOLM13	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.6753314614150554	[193]	[223]	5	hSpCas9	negative selection	11600726
22827309	22827332	11	-	28162770	MOLM13	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.6234254014660912	[570]	[635]	5	hSpCas9	negative selection	11600727
22827207	22827230	11	-	28162770	MOLM13	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	1.699515082659064	[355]	[835]	9	hSpCas9	negative selection	11600728
22827847	22827870	11	-	28162770	HEL	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.6427388320003571	[387]	[387]	5	hSpCas9	negative selection	11770091
22827205	22827228	11	+	28162770	HEL	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	1.078534891445998	[206]	[279]	8	hSpCas9	negative selection	11770092
22827309	22827332	11	-	28162770	HEL	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	0.4099222681964968	[462]	[393]	3	hSpCas9	negative selection	11770093
22827207	22827230	11	-	28162770	HEL	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.542889903635295	[328]	[306]	4	hSpCas9	negative selection	11770094
22827847	22827870	11	-	28162770	MV411	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	1.2132709476315835	[234]	[458]	9	hSpCas9	negative selection	11939457
22827205	22827228	11	+	28162770	MV411	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.16475719872724315	[168]	[126]	-1	hSpCas9	negative selection	11939458
22827309	22827332	11	-	28162770	MV411	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	1.218773792530632	[304]	[597]	9	hSpCas9	negative selection	11939459
22827207	22827230	11	-	28162770	MV411	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.5418849092480305	[264]	[324]	5	hSpCas9	negative selection	11939460
22827847	22827870	11	-	28162770	MONOMAC1	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.5123730245860909	[147]	[241]	5	hSpCas9	negative selection	12108823
22827205	22827228	11	+	28162770	MONOMAC1	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	-0.0347654181606768	[83]	[93]	0	hSpCas9	negative selection	12108824
22827309	22827332	11	-	28162770	MONOMAC1	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	1.0988960392948641	[223]	[549]	8	hSpCas9	negative selection	12108825
22827207	22827230	11	-	28162770	MONOMAC1	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.04898158175863865	[198]	[235]	0	hSpCas9	negative selection	12108826
22827847	22827870	11	-	28162770	OCIAML2	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.23607794783136438	[52]	[345]	2	hSpCas9	negative selection	12278189
22827205	22827228	11	+	28162770	OCIAML2	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.5928731170639967	[24]	[208]	6	hSpCas9	negative selection	12278190
22827309	22827332	11	-	28162770	OCIAML2	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	-0.09582217075185007	[74]	[388]	-1	hSpCas9	negative selection	12278191
22827207	22827230	11	-	28162770	OCIAML2	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.7586162671353489	[44]	[421]	7	hSpCas9	negative selection	12278192
22827847	22827870	11	-	28162770	OCIAML3	viability	GAAAAGAGCAAAGCTTGCAGAGG	SVIP	ENSG00000198168	0.3581638345852217	[68]	[266]	3	hSpCas9	negative selection	12447555
22827205	22827228	11	+	28162770	OCIAML3	viability	ACCCTAAGTCCACCTTCTGGTGG	SVIP	ENSG00000198168	0.95348015497833	[25]	[151]	8	hSpCas9	negative selection	12447556
22827309	22827332	11	-	28162770	OCIAML3	viability	ATTTCTTCAAGGCTGCATCTCGG	SVIP	ENSG00000198168	-0.196528512429624	[92]	[244]	-1	hSpCas9	negative selection	12447557
22827207	22827230	11	-	28162770	OCIAML3	viability	CCCCACCAGAAGGTGGACTTAGG	SVIP	ENSG00000198168	0.21334728173344097	[93]	[328]	2	hSpCas9	negative selection	12447558