Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6389
• Symbol: SdhA
• Description: succinate dehydrogenase complex flavoprotein subunit A

DataSource: http://genomecrispr.dkfz.de/#!/results/SdhA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
230990	231013	5	-	26472758	Jiyoye	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-1.0522562371314237	[296]	[107]	-6	hSpCas9	negative selection	143548
251435	251458	5	+	26472758	Jiyoye	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-2.4452674300802686	[64]	[8]	-8	hSpCas9	negative selection	143549
233565	233588	5	+	26472758	Jiyoye	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.7152976768682052	[62]	[77]	5	hSpCas9	negative selection	143550
236498	236521	5	-	26472758	Jiyoye	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.207534462609335	[97]	[7]	-9	hSpCas9	negative selection	143551
225514	225537	5	+	26472758	Jiyoye	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.4001795405517306	[118]	[16]	-8	hSpCas9	negative selection	143552
225549	225572	5	-	26472758	Jiyoye	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-2.8658431129005426	[28]	[2]	-9	hSpCas9	negative selection	143553
230910	230933	5	+	26472758	Jiyoye	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-0.9272436575646859	[57]	[22]	-6	hSpCas9	negative selection	143554
235314	235337	5	+	26472758	Jiyoye	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.4607210824867813	[145]	[19]	-9	hSpCas9	negative selection	143555
218367	218390	5	-	26472758	Jiyoye	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-1.0623099017953468	[215]	[77]	-6	hSpCas9	negative selection	143556
235292	235315	5	+	26472758	Jiyoye	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.0333972098801083	[151]	[13]	-9	hSpCas9	negative selection	143557
230990	231013	5	-	26472758	KBM7	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.7777411644036349	[1084,893]	[316,227]	-6	hSpCas9	negative selection	334666
251435	251458	5	+	26472758	KBM7	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.7362649614963606	[218,171]	[38,16]	-8	hSpCas9	negative selection	334667
233565	233588	5	+	26472758	KBM7	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.6565482037273799	[293,91]	[58,204]	7	hSpCas9	negative selection	334668
236498	236521	5	-	26472758	KBM7	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-2.9671368157909046	[375,259]	[30,7]	-9	hSpCas9	negative selection	334669
225514	225537	5	+	26472758	KBM7	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.536730301812655	[906,785]	[50,83]	-9	hSpCas9	negative selection	334670
225549	225572	5	-	26472758	KBM7	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-2.29040387353477	[272,189]	[3,37]	-8	hSpCas9	negative selection	334671
230910	230933	5	+	26472758	KBM7	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-4.017852700064777	[401,335]	[16,4]	-9	hSpCas9	negative selection	334672
235314	235337	5	+	26472758	KBM7	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-3.0963542953732013	[495,619]	[8,50]	-9	hSpCas9	negative selection	334673
218367	218390	5	-	26472758	KBM7	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.478932530089314	[898,751]	[261,290]	-4	hSpCas9	negative selection	334674
235292	235315	5	+	26472758	KBM7	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-1.9699198729971072	[715,507]	[52,89]	-8	hSpCas9	negative selection	334675
230990	231013	5	-	26472758	Raji	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-1.259733333280018	[453]	[43]	-7	hSpCas9	negative selection	525784
251435	251458	5	+	26472758	Raji	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-2.097730894531013	[165]	[8]	-8	hSpCas9	negative selection	525785
233565	233588	5	+	26472758	Raji	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.15041422209404742	[109]	[22]	-1	hSpCas9	negative selection	525786
236498	236521	5	-	26472758	Raji	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-4.140543978069987	[227]	[2]	-9	hSpCas9	negative selection	525787
225514	225537	5	+	26472758	Raji	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.6140412078968285	[276]	[20]	-8	hSpCas9	negative selection	525788
225549	225572	5	-	26472758	Raji	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.4946524787064983	[84]	[13]	-4	hSpCas9	negative selection	525789
230910	230933	5	+	26472758	Raji	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.0890136774299042	[164]	[17]	-7	hSpCas9	negative selection	525790
235314	235337	5	+	26472758	Raji	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.472560890580932	[286]	[11]	-9	hSpCas9	negative selection	525791
218367	218390	5	-	26472758	Raji	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-1.1233966714555677	[459]	[48]	-7	hSpCas9	negative selection	525792
235292	235315	5	+	26472758	Raji	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-0.7670855825425416	[241]	[32]	-5	hSpCas9	negative selection	525793
230990	231013	5	-	26472758	K562	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-1.6403676812352077	[841]	[227]	-7	hSpCas9	negative selection	716902
251435	251458	5	+	26472758	K562	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-4.933499064529396	[180]	[4]	-9	hSpCas9	negative selection	716903
233565	233588	5	+	26472758	K562	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.05514155419246092	[127]	[103]	0	hSpCas9	negative selection	716904
236498	236521	5	-	26472758	K562	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-5.821670462791325	[267]	[3]	-9	hSpCas9	negative selection	716905
225514	225537	5	+	26472758	K562	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.3405437730547094	[641]	[106]	-8	hSpCas9	negative selection	716906
225549	225572	5	-	26472758	K562	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-4.373558830282673	[220]	[8]	-9	hSpCas9	negative selection	716907
230910	230933	5	+	26472758	K562	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-3.0930223665922396	[373]	[36]	-8	hSpCas9	negative selection	716908
235314	235337	5	+	26472758	K562	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.3525164147207853	[362]	[59]	-8	hSpCas9	negative selection	716909
218367	218390	5	-	26472758	K562	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	0.3725391907744139	[602]	[658]	3	hSpCas9	negative selection	716910
235292	235315	5	+	26472758	K562	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-1.3201951276629067	[351]	[118]	-6	hSpCas9	negative selection	716911
220236	220259	5	-	26627737	DLD1	viability	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.05337779540019638	[183]	[51,12,104]	0	hSpCas9	negative selection	828551
225545	225568	5	-	26627737	DLD1	viability	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.08790873658253762	[303]	[55,164,86]	0	hSpCas9	negative selection	828553
235209	235232	5	-	26627737	DLD1	viability	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-3.253467986589943	[951]	[24,14,49]	-9	hSpCas9	negative selection	828554
220236	220259	5	-	26627737	GBM cells	viability after 5 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.36064460961257105	[113]	[76,79]	5	hSpCas9	negative selection	910866
225545	225568	5	-	26627737	GBM cells	viability after 5 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	1.0244447569695445	[76]	[78,88]	9	hSpCas9	negative selection	910868
235209	235232	5	-	26627737	GBM cells	viability after 5 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.7853513160624855	[250]	[233,229]	9	hSpCas9	negative selection	910869
220236	220259	5	-	26627737	GBM cells	viability after 13 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.42527464143454674	[113]	[135,39]	5	hSpCas9	negative selection	993181
225545	225568	5	-	26627737	GBM cells	viability after 13 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.5269729216285035	[76]	[41,74]	6	hSpCas9	negative selection	993183
235209	235232	5	-	26627737	GBM cells	viability after 13 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.4122796954166872	[250]	[167,191]	5	hSpCas9	negative selection	993184
220236	220259	5	-	26627737	GBM cells	viability after 21 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.24220955514308862	[113]	[78,67]	2	hSpCas9	negative selection	1075496
225545	225568	5	-	26627737	GBM cells	viability after 21 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	1.2460381225996675	[76]	[93,103]	9	hSpCas9	negative selection	1075498
235209	235232	5	-	26627737	GBM cells	viability after 21 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.26692579305571457	[250]	[173,154]	2	hSpCas9	negative selection	1075499
220236	220259	5	-	26627737	RPE1	viability after 9 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	1.252786339086758	[97]	[128,0]	7	hSpCas9	negative selection	1157811
225545	225568	5	-	26627737	RPE1	viability after 9 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-3.105811588544759	[499]	[15,20]	-9	hSpCas9	negative selection	1157813
235209	235232	5	-	26627737	RPE1	viability after 9 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	1.0929231963303427	[565]	[487,235]	6	hSpCas9	negative selection	1157814
220236	220259	5	-	26627737	RPE1	viability after 12 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	1.035525537001333	[97]	[103,0]	6	hSpCas9	negative selection	1240126
225545	225568	5	-	26627737	RPE1	viability after 12 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-2.795943866358919	[499]	[13,24]	-9	hSpCas9	negative selection	1240128
235209	235232	5	-	26627737	RPE1	viability after 12 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.5456833482046983	[565]	[135,312]	3	hSpCas9	negative selection	1240129
220236	220259	5	-	26627737	RPE1	viability after 15 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	3.000984330590038	[97]	[450,0]	9	hSpCas9	negative selection	1322441
225545	225568	5	-	26627737	RPE1	viability after 15 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-2.192262824426898	[499]	[61,0]	-8	hSpCas9	negative selection	1322443
235209	235232	5	-	26627737	RPE1	viability after 15 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.5701381572294404	[565]	[225,248]	3	hSpCas9	negative selection	1322444
220236	220259	5	-	26627737	RPE1	viability after 18 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	2.536050685790267	[97]	[295,0]	9	hSpCas9	negative selection	1404756
225545	225568	5	-	26627737	RPE1	viability after 18 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-1.9643251991037876	[499]	[65,0]	-8	hSpCas9	negative selection	1404758
235209	235232	5	-	26627737	RPE1	viability after 18 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.2080500729060653	[565]	[232,115]	1	hSpCas9	negative selection	1404759
220236	220259	5	-	26627737	HeLa	viability after 8 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-2.079030025704621	[392]	[6,50,54]	-9	hSpCas9	negative selection	1487071
225545	225568	5	-	26627737	HeLa	viability after 8 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.44042664680855337	[189]	[79,1,101]	-4	hSpCas9	negative selection	1487073
235209	235232	5	-	26627737	HeLa	viability after 8 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.1507071295996159	[429]	[279,209,152]	1	hSpCas9	negative selection	1487074
220236	220259	5	-	26627737	HeLa	viability after 12 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-1.5725699776060433	[392]	[17,89,50]	-8	hSpCas9	negative selection	1569386
225545	225568	5	-	26627737	HeLa	viability after 12 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-1.0969494983636634	[189]	[1,84,16]	-7	hSpCas9	negative selection	1569388
235209	235232	5	-	26627737	HeLa	viability after 12 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.12905014321423258	[429]	[76,331,155]	1	hSpCas9	negative selection	1569389
220236	220259	5	-	26627737	HeLa	viability after 15 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-1.6973394781753175	[392]	[83,32,28]	-9	hSpCas9	negative selection	1651701
225545	225568	5	-	26627737	HeLa	viability after 15 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.03369890584463264	[189]	[35,105,85]	0	hSpCas9	negative selection	1651703
235209	235232	5	-	26627737	HeLa	viability after 15 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.4624522560172626	[429]	[178,272,274]	4	hSpCas9	negative selection	1651704
220236	220259	5	-	26627737	HeLa	viability after 18 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-1.5988652129582583	[392]	[60,29,28]	-8	hSpCas9	negative selection	1734016
225545	225568	5	-	26627737	HeLa	viability after 18 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.03734894230871788	[189]	[21,89,85]	0	hSpCas9	negative selection	1734018
235209	235232	5	-	26627737	HeLa	viability after 18 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	0.46937271112486745	[429]	[119,228,274]	4	hSpCas9	negative selection	1734019
220236	220259	5	-	26627737	HCT116	viability after 6 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-2.138094664870037	[27]	[0,0]	-8	hSpCas9	negative selection	1816331
225545	225568	5	-	26627737	HCT116	viability after 6 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-3.0276965856218148	[399]	[8,6]	-9	hSpCas9	negative selection	1816333
235209	235232	5	-	26627737	HCT116	viability after 6 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.5944122344227554	[850]	[91,17]	-7	hSpCas9	negative selection	1816334
220236	220259	5	-	26627737	HCT116	viability after 8 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	1.9808711809910997	[31]	[124,31,52]	9	hSpCas9	negative selection	1898646
225545	225568	5	-	26627737	HCT116	viability after 8 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	2.4874509632530826	[28]	[64,80,121]	9	hSpCas9	negative selection	1898648
235209	235232	5	-	26627737	HCT116	viability after 8 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-0.9663871624483293	[363]	[108,90,107]	-8	hSpCas9	negative selection	1898649
220236	220259	5	-	26627737	HCT116	viability after 9 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	4.07934357849094	[27]	[136,117]	9	hSpCas9	negative selection	1980961
225545	225568	5	-	26627737	HCT116	viability after 9 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.6439684223869674	[399]	[126,21]	-4	hSpCas9	negative selection	1980963
235209	235232	5	-	26627737	HCT116	viability after 9 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-0.8487870137207314	[850]	[52,183]	-5	hSpCas9	negative selection	1980964
220236	220259	5	-	26627737	HCT116	viability after 12 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	2.2563862822062033	[31]	[111,27,96]	9	hSpCas9	negative selection	2063276
225545	225568	5	-	26627737	HCT116	viability after 12 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	2.576288810435745	[28]	[68,65,138]	9	hSpCas9	negative selection	2063278
235209	235232	5	-	26627737	HCT116	viability after 12 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.6750461971596695	[363]	[54,53,70]	-9	hSpCas9	negative selection	2063279
220236	220259	5	-	26627737	HCT116	viability after 15 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	1.2278979735038087	[31]	[22,2,99]	8	hSpCas9	negative selection	2145591
225545	225568	5	-	26627737	HCT116	viability after 15 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	2.291536834927883	[28]	[92,70,81]	9	hSpCas9	negative selection	2145593
235209	235232	5	-	26627737	HCT116	viability after 15 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-2.5811231310990803	[363]	[44,23,36]	-9	hSpCas9	negative selection	2145594
220236	220259	5	-	26627737	HCT116	viability after 18 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	2.545408282307745	[31]	[97,0,181]	9	hSpCas9	negative selection	2227906
225545	225568	5	-	26627737	HCT116	viability after 18 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	2.5909589052091437	[28]	[80,97,72]	9	hSpCas9	negative selection	2227908
235209	235232	5	-	26627737	HCT116	viability after 18 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-3.2366663056875007	[363]	[40,0,14]	-9	hSpCas9	negative selection	2227909
218319	218342	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGACTGGCGGGACTGCGCGG	SDHA	ENSG00000073578	1.4381272854743918	[234,28]	[146,2]	5	dCas9-VP64	positive selection	2465998
218340	218363	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGGCAACAGCAGACATGTCGG	SDHA	ENSG00000073578	1.2074885537855162	[40,101]	[22,50]	5	dCas9-VP64	positive selection	2466003
218289	218312	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCTGCGCACCACACCGGGG	SDHA	ENSG00000073578	3.7826191714798436	[68,98]	[217,297]	9	dCas9-VP64	positive selection	2466004
218319	218342	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGACTGGCGGGACTGCGCGG	SDHA	ENSG00000073578	0.20958158318911396	[67,78]	[34,19]	1	dCas9-VP64	positive selection	2561253
218340	218363	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGGCAACAGCAGACATGTCGG	SDHA	ENSG00000073578	0.3936572358034104	[39,137]	[61,14]	3	dCas9-VP64	positive selection	2561258
218289	218312	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCTGCGCACCACACCGGGG	SDHA	ENSG00000073578	0.5784018372562145	[138,103]	[42,74]	4	dCas9-VP64	positive selection	2561259
228313	228336	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	-1.3496120671682306	[2,2]	[0,0]	-9	hSpCas9	positive selection	3019142
225515	225538	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-0.7583759454071983	[3,3]	[1,0]	-8	hSpCas9	positive selection	3019143
228313	228336	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	-0.9164258951014222	[2,2]	[1,0]	-9	hSpCas9	positive selection	3087000
225515	225538	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	0.2815335296972551	[3,3]	[1,3]	5	hSpCas9	positive selection	3087001
223508	223531		-	24336571	A375	resistance to PLX after 7 days	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	0.37156510398102016	[3,3]	[5,4]	8	hSpCas9	positive selection	3143082
224423	224446		+	24336571	A375	resistance to PLX after 7 days	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.04848877076628805	[14,13]	[13,14]	1	hSpCas9	positive selection	3143083
223512	223535		+	24336571	A375	resistance to PLX after 7 days	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.3672745424721525	[8,6]	[10,8]	8	hSpCas9	positive selection	3143084
224446	224469		-	24336571	A375	resistance to PLX after 7 days	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.2889723649674447	[2,3]	[3,4]	7	hSpCas9	positive selection	3143085
223508	223531		-	24336571	A375	resistance to PLX after 14 days	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	0.39643070451708384	[2,4]	[1,1]	4	hSpCas9	positive selection	3200875
224423	224446		+	24336571	A375	resistance to PLX after 14 days	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.31109892964538555	[14,18]	[8,9]	3	hSpCas9	positive selection	3200876
223512	223535		+	24336571	A375	resistance to PLX after 14 days	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.9842792400979197	[7,9]	[5,9]	7	hSpCas9	positive selection	3200877
224446	224469		-	24336571	A375	resistance to PLX after 14 days	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.14595358420301752	[1,4]	[1,1]	1	hSpCas9	positive selection	3200878
223508	223531		-	24336571	A375	viability after 7 days	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	-0.21693329798353722	[4]	[3,3]	-3	hSpCas9	negative selection	3258668
224423	224446		+	24336571	A375	viability after 7 days	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.8081717693426251	[7]	[14,13]	9	hSpCas9	negative selection	3258669
223512	223535		+	24336571	A375	viability after 7 days	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.7807019100219355	[4]	[8,6]	9	hSpCas9	negative selection	3258670
224446	224469		-	24336571	A375	viability after 7 days	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-1.0594752700451677	[7]	[2,3]	-9	hSpCas9	negative selection	3258671
223508	223531		-	24336571	A375	viability after 14 days	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	-0.21281321443780765	[4]	[2,4]	-3	hSpCas9	negative selection	3316461
224423	224446		+	24336571	A375	viability after 14 days	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	1.0877065671788995	[7]	[14,18]	9	hSpCas9	negative selection	3316462
223512	223535		+	24336571	A375	viability after 14 days	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.9670732381828424	[4]	[7,9]	9	hSpCas9	negative selection	3316463
224446	224469		-	24336571	A375	viability after 14 days	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.9484416827736717	[7]	[1,4]	-8	hSpCas9	negative selection	3316464
225523	225546	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3391560
224446	224469	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.6130385081375694	[233,233]	[0,0]	-4	hSpCas9	positive selection	3391561
226021	226044	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	2.2696746038734803	[348,348]	[10,10]	8	hSpCas9	positive selection	3391562
228312	228335	5	+	26780180	HT29	viability (Avana library 4 designs)	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	2.87345553431524	[]	[]	8	hSpCas9	negative selection	3457576
230930	230953	5	+	26780180	HT29	viability (Avana library 4 designs)	CGGCACGGCCATGATCACCAGGG	SDHA	ENSG00000073578	5.09998207231951	[]	[]	9	hSpCas9	negative selection	3457577
233488	233511	5	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGTTGTCTCATTACGGAAGG	SDHA	ENSG00000073578	3.72744164947536	[]	[]	9	hSpCas9	negative selection	3457578
225514	225537	5	+	26780180	HT29	viability (Avana library 4 designs)	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	3.77173912793011	[]	[]	9	hSpCas9	negative selection	3457579
230930	230953	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCACGGCCATGATCACCAGGG	SDHA	ENSG00000073578	-16.8970721898024	[]	[]	-9	hSpCas9	negative selection	3556594
233488	233511	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGTTGTCTCATTACGGAAGG	SDHA	ENSG00000073578	-0.987990964039805	[]	[]	-1	hSpCas9	negative selection	3556595
228312	228335	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	-3.77423446353599	[]	[]	-4	hSpCas9	negative selection	3556596
225514	225537	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-15.5721965456575	[]	[]	-9	hSpCas9	negative selection	3556597
230930	230953	5	+	26780180	A375	viability (Avana lentiGuide)	CGGCACGGCCATGATCACCAGGG	SDHA	ENSG00000073578	23.7632867727605	[]	[]	9	hSpCas9	negative selection	3665253
233488	233511	5	+	26780180	A375	viability (Avana lentiGuide)	GCTGGTTGTCTCATTACGGAAGG	SDHA	ENSG00000073578	21.9266138771689	[]	[]	9	hSpCas9	negative selection	3665254
228312	228335	5	+	26780180	A375	viability (Avana lentiGuide)	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	11.179840334438	[]	[]	7	hSpCas9	negative selection	3665255
225514	225537	5	+	26780180	A375	viability (Avana lentiGuide)	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	23.1859960578861	[]	[]	9	hSpCas9	negative selection	3665256
230930	230953	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCACGGCCATGATCACCAGGG	SDHA	ENSG00000073578	-1.3370194654570557	[4]	[0,1]	-9	hSpCas9	positive selection	3773860
233488	233511	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGTTGTCTCATTACGGAAGG	SDHA	ENSG00000073578	0.015412794982202188	[5]	[6,5]	0	hSpCas9	positive selection	3773861
228312	228335	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	-0.33274374040889726	[4]	[4,2]	-5	hSpCas9	positive selection	3773862
225514	225537	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.0978201758455686	[5]	[2,1]	-9	hSpCas9	positive selection	3773863
230930	230953	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCACGGCCATGATCACCAGGG	SDHA	ENSG00000073578	-1.3959363593997307	[5]	[0,1]	-9	hSpCas9	positive selection	3882467
233488	233511	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGTTGTCTCATTACGGAAGG	SDHA	ENSG00000073578	-0.9599710719965413	[6]	[3,1]	-8	hSpCas9	positive selection	3882468
228312	228335	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAACACTGTTGTTGCCACAGGG	SDHA	ENSG00000073578	-0.28450089286920976	[4]	[4,2]	-4	hSpCas9	positive selection	3882469
225514	225537	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-0.32160362373778817	[5]	[3,2]	-4	hSpCas9	positive selection	3882470
226034	226057	5	-	26780180	A375	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.133782120143593	[]	[]	0	hSpCas9	negative selection	3992514
224423	224446	5	+	26780180	A375	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	-0.252891357292823	[]	[]	-7	hSpCas9	negative selection	3992515
225549	225572	5	-	26780180	A375	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	1.52623681519918	[]	[]	8	hSpCas9	negative selection	3992516
225523	225546	5	-	26780180	A375	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	2.30589080313957	[]	[]	9	hSpCas9	negative selection	3992517
224446	224469	5	-	26780180	A375	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	1.4103527245985	[]	[]	7	hSpCas9	negative selection	3992518
226021	226044	5	+	26780180	A375	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.594422512603483	[]	[]	1	hSpCas9	negative selection	3992519
226034	226057	5	-	26780180	HT29	viability (GeCKOv2 library)	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.470175484596239	[]	[]	1	hSpCas9	negative selection	4100480
224423	224446	5	+	26780180	HT29	viability (GeCKOv2 library)	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.312271941816361	[]	[]	0	hSpCas9	negative selection	4100481
225549	225572	5	-	26780180	HT29	viability (GeCKOv2 library)	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	1.38431560562669	[]	[]	7	hSpCas9	negative selection	4100482
225523	225546	5	-	26780180	HT29	viability (GeCKOv2 library)	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	1.84263082911901	[]	[]	8	hSpCas9	negative selection	4100483
224446	224469	5	-	26780180	HT29	viability (GeCKOv2 library)	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	1.5192759858833	[]	[]	7	hSpCas9	negative selection	4100484
226021	226044	5	+	26780180	HT29	viability (GeCKOv2 library)	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.297733220536979	[]	[]	0	hSpCas9	negative selection	4100485
223508	223531	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	-0.02020603178719943	[2]	[2,0]	0	hSpCas9	positive selection	4168875
224423	224446	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.28995601309079827	[3]	[1,3]	7	hSpCas9	positive selection	4168876
223512	223535	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.024864861365579305	[3]	[1,2]	0	hSpCas9	positive selection	4168877
224446	224469	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.5560116112950227	[2]	[1,0]	-9	hSpCas9	positive selection	4168878
223508	223531	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACAGTGAAGTGAAAACCTCGG	SDHA	ENSG00000073578	0.8248217871559304	[3]	[0,2,0,3]	5	hSpCas9	positive selection	4232897
224423	224446	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.15762300667453602	[3]	[2,2,1,0]	1	hSpCas9	positive selection	4232898
223512	223535	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTTTCACTTCACTGTTGATGG	SDHA	ENSG00000073578	0.91097903771783	[3]	[2,0,0,3]	6	hSpCas9	positive selection	4232899
224446	224469	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.4593947529742124	[3]	[0,1,0,0]	-6	hSpCas9	positive selection	4232900
225549	225572	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.043138311739280844	[2]	[2,0]	-1	hSpCas9	positive selection	4296763
226034	226057	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.2631111831324674	[2]	[2,1]	5	hSpCas9	positive selection	4296764
224423	224446	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.4255011800674614	[4]	[4,4]	8	hSpCas9	positive selection	4296765
225523	225546	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.16477507334700595	[3]	[3,1]	-3	hSpCas9	positive selection	4361017
224446	224469	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.28925385441932455	[3]	[3,2]	6	hSpCas9	positive selection	4361018
226021	226044	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	-0.17595894452858926	[3]	[3,0]	-4	hSpCas9	positive selection	4361019
223523	223545	5	+	27760321	OCIAML3	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-0.34951887614952	[315,309]	[189,195]	-4	hSpCas9	negative selection	4437442
224439	224461	5	+	27760321	OCIAML3	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.6132139050686007	[732,704]	[779,967]	7	hSpCas9	negative selection	4437443
225545	225567	5	-	27760321	OCIAML3	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.6413291696619057	[1245,896]	[1154,1474]	7	hSpCas9	negative selection	4437444
230872	230894	5	-	27760321	OCIAML3	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-1.1994776389076522	[932,787]	[248,347]	-8	hSpCas9	negative selection	4437445
233566	233588	5	+	27760321	OCIAML3	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.5291425642867409	[867,705]	[811,976]	6	hSpCas9	negative selection	4437446
223523	223545	5	+	27760321	OCIAML2	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-0.7627000764666225	[315,309]	[143,156]	-7	hSpCas9	negative selection	4520905
224439	224461	5	+	27760321	OCIAML2	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.20348703934772572	[732,704]	[521,866]	2	hSpCas9	negative selection	4520906
225545	225567	5	-	27760321	OCIAML2	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.4250067250363654	[1245,896]	[1003,1346]	6	hSpCas9	negative selection	4520907
230872	230894	5	-	27760321	OCIAML2	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-1.4736283036802003	[932,787]	[203,309]	-8	hSpCas9	negative selection	4520908
233566	233588	5	+	27760321	OCIAML2	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.04873940716625402	[867,705]	[469,898]	0	hSpCas9	negative selection	4520909
223523	223545	5	+	27760321	MV411	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-1.0447806897188656	[315,309]	[61,157]	-6	hSpCas9	negative selection	4604368
224439	224461	5	+	27760321	MV411	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.50321018107924	[732,704]	[707,621]	3	hSpCas9	negative selection	4604369
225545	225567	5	-	27760321	MV411	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.34898525279238024	[1245,896]	[1018,699]	2	hSpCas9	negative selection	4604370
230872	230894	5	-	27760321	MV411	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-1.9890921133040131	[932,787]	[44,288]	-8	hSpCas9	negative selection	4604371
233566	233588	5	+	27760321	MV411	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.3336317968219832	[867,705]	[395,430]	-2	hSpCas9	negative selection	4604372
223523	223545	5	+	27760321	HL60	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-2.0031297655518236	[315,309]	[61,65]	-9	hSpCas9	negative selection	4687831
224439	224461	5	+	27760321	HL60	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	-0.04166432110565299	[732,704]	[540,603]	0	hSpCas9	negative selection	4687832
225545	225567	5	-	27760321	HL60	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.5892984000437056	[1245,896]	[1223,1387]	7	hSpCas9	negative selection	4687833
230872	230894	5	-	27760321	HL60	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-1.5239847902744543	[932,787]	[310,171]	-8	hSpCas9	negative selection	4687834
233566	233588	5	+	27760321	HL60	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.42523576571401556	[867,705]	[818,900]	5	hSpCas9	negative selection	4687835
223523	223545	5	+	27760321	HT1080	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-1.5604467686129584	[309,241]	[0,76]	-5	hSpCas9	negative selection	4771294
224439	224461	5	+	27760321	HT1080	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.9324595007931088	[704,549]	[562,382]	5	hSpCas9	negative selection	4771295
225545	225567	5	-	27760321	HT1080	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.591151015570197	[896,699]	[224,195]	-3	hSpCas9	negative selection	4771296
230872	230894	5	-	27760321	HT1080	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-1.9602615186682855	[787,614]	[88,52]	-6	hSpCas9	negative selection	4771297
233566	233588	5	+	27760321	HT1080	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-1.1865909904337282	[705,550]	[109,109]	-5	hSpCas9	negative selection	4771298
223523	223545	5	+	27760321	HT29	viability after 7 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.03106764256069705	[309,241]	[552,281,281]	0	hSpCas9	negative selection	4854757
224439	224461	5	+	27760321	HT29	viability after 7 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	-0.32574661325294246	[704,549]	[782,521,644]	-5	hSpCas9	negative selection	4854758
225545	225567	5	-	27760321	HT29	viability after 7 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.6976842909193794	[896,699]	[1911,1511,1605]	9	hSpCas9	negative selection	4854759
230872	230894	5	-	27760321	HT29	viability after 7 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	0.10491059417280302	[787,614]	[1038,835,1040]	1	hSpCas9	negative selection	4854760
233566	233588	5	+	27760321	HT29	viability after 7 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.4511098563029421	[705,550]	[1562,968,853]	7	hSpCas9	negative selection	4854761
223523	223545	5	+	27760321	HT29	viability after 25 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.22379507183577851	[309,241]	[218,542,349]	2	hSpCas9	negative selection	4938220
224439	224461	5	+	27760321	HT29	viability after 25 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.15093132375673424	[704,549]	[710,865,817]	1	hSpCas9	negative selection	4938221
225545	225567	5	-	27760321	HT29	viability after 25 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.835309476480457	[896,699]	[1470,1473,1983]	8	hSpCas9	negative selection	4938222
230872	230894	5	-	27760321	HT29	viability after 25 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-0.6597277156875061	[787,614]	[441,556,528]	-5	hSpCas9	negative selection	4938223
233566	233588	5	+	27760321	HT29	viability after 25 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.7123554637516105	[705,550]	[1206,1055,1273]	7	hSpCas9	negative selection	4938224
223523	223545	5	+	27760321	HT29	viability after 22 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.09158116379474585	[309,241]	[410,164,442]	0	hSpCas9	negative selection	5021683
224439	224461	5	+	27760321	HT29	viability after 22 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.06714700135907847	[704,549]	[699,766,814]	0	hSpCas9	negative selection	5021684
225545	225567	5	-	27760321	HT29	viability after 22 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.9595844114075616	[896,699]	[1743,1941,1699]	9	hSpCas9	negative selection	5021685
230872	230894	5	-	27760321	HT29	viability after 22 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-0.5687122163043691	[787,614]	[547,571,519]	-5	hSpCas9	negative selection	5021686
233566	233588	5	+	27760321	HT29	viability after 22 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.35911278137821556	[705,550]	[753,1069,976]	4	hSpCas9	negative selection	5021687
223523	223545	5	+	27760321	HT29	viability after 19 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	-0.018683640173171034	[309,241]	[366,197,372]	0	hSpCas9	negative selection	5105146
224439	224461	5	+	27760321	HT29	viability after 19 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.3673559532083911	[704,549]	[693,908,1140]	3	hSpCas9	negative selection	5105147
225545	225567	5	-	27760321	HT29	viability after 19 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.9286205392146403	[896,699]	[1512,1722,1945]	8	hSpCas9	negative selection	5105148
230872	230894	5	-	27760321	HT29	viability after 19 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-0.18874208367193357	[787,614]	[741,582,786]	-2	hSpCas9	negative selection	5105149
233566	233588	5	+	27760321	HT29	viability after 19 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.9507085912854785	[705,550]	[1213,1822,1121]	8	hSpCas9	negative selection	5105150
223523	223545	5	+	27760321	HT29	viability after 16 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.18022385362899532	[309,241]	[213,148,678]	2	hSpCas9	negative selection	5188609
224439	224461	5	+	27760321	HT29	viability after 16 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	0.061882682328139316	[704,549]	[636,779,770]	0	hSpCas9	negative selection	5188610
225545	225567	5	-	27760321	HT29	viability after 16 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.9623858968542043	[896,699]	[2259,1701,1309]	9	hSpCas9	negative selection	5188611
230872	230894	5	-	27760321	HT29	viability after 16 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	0.040733006307235975	[787,614]	[1112,833,502]	0	hSpCas9	negative selection	5188612
233566	233588	5	+	27760321	HT29	viability after 16 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.28431880574766977	[705,550]	[935,833,806]	3	hSpCas9	negative selection	5188613
223523	223545	5	+	27760321	HT29	viability after 13 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.2362363479824579	[309,241]	[350,292,480]	3	hSpCas9	negative selection	5272072
224439	224461	5	+	27760321	HT29	viability after 13 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	-0.2383365889507315	[704,549]	[586,659,604]	-3	hSpCas9	negative selection	5272073
225545	225567	5	-	27760321	HT29	viability after 13 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.794685711530464	[896,699]	[1551,1736,1535]	9	hSpCas9	negative selection	5272074
230872	230894	5	-	27760321	HT29	viability after 13 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-0.08990073505147633	[787,614]	[738,979,585]	-1	hSpCas9	negative selection	5272075
233566	233588	5	+	27760321	HT29	viability after 13 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.6337812618513343	[705,550]	[1158,1414,837]	7	hSpCas9	negative selection	5272076
223523	223545	5	+	27760321	HT29	viability after 10 days	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.4887039149805099	[309,241]	[562,516,373]	6	hSpCas9	negative selection	5355535
224439	224461	5	+	27760321	HT29	viability after 10 days	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	-0.12832526676695533	[704,549]	[686,645,812]	-2	hSpCas9	negative selection	5355536
225545	225567	5	-	27760321	HT29	viability after 10 days	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.6408256636185938	[896,699]	[1561,1566,1534]	8	hSpCas9	negative selection	5355537
230872	230894	5	-	27760321	HT29	viability after 10 days	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	0.070706024464807	[787,614]	[1021,945,794]	0	hSpCas9	negative selection	5355538
233566	233588	5	+	27760321	HT29	viability after 10 days	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.5174473326863462	[705,550]	[1137,1184,1049]	7	hSpCas9	negative selection	5355539
223523	223545	5	+	27760321	MOLM13	viability	CACTGTTGATGGGAACAAGAGG	SDHA	ENSG00000073578	0.9406910059644198	[315,309]	[718,16]	6	hSpCas9	negative selection	5438998
224439	224461	5	+	27760321	MOLM13	viability	CATTTGGCCTTTCTGAGGCAGG	SDHA	ENSG00000073578	-0.489483177837269	[732,704]	[128,425]	-3	hSpCas9	negative selection	5438999
225545	225567	5	-	27760321	MOLM13	viability	TCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.25126496985261215	[1245,896]	[1010,457]	1	hSpCas9	negative selection	5439000
230872	230894	5	-	27760321	MOLM13	viability	TAGGTGCGCCCGTAGCCTCTGG	SDHA	ENSG00000073578	-2.0035232580697286	[932,787]	[64,167]	-8	hSpCas9	negative selection	5439001
233566	233588	5	+	27760321	MOLM13	viability	CGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.6519797805499161	[867,705]	[218,333]	-4	hSpCas9	negative selection	5439002
218341	218364	5	+	27661255	K562	viability	GCGGCAACAGCAGACATGTCGGG	SDHA	ENSG00000073578	-0.7085918456868017	[853,718]	[437,340]	-8	dCas9-KRAB	negative selection	5509781
218515	218538	5	+	27661255	K562	viability	GGTCCCTGCGCCCTCTGTCCCGG	SDHA	ENSG00000073578	0.20345161101916373	[719,776]	[673,698]	7	dCas9-KRAB	negative selection	5509782
225549	225572	5	-	27260156	BXPC3	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.17463769366117565	[258]	[268,276,304,384]	4	hSpCas9	negative selection	5569223
226034	226057	5	-	27260156	BXPC3	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.18338712781698885	[236]	[274,300,312,227]	4	hSpCas9	negative selection	5569224
224423	224446	5	+	27260156	BXPC3	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.3744320943008099	[1204]	[1464,1623,1662,1810]	7	hSpCas9	negative selection	5569225
225523	225546	5	-	27260156	BXPC3	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.19521254850938827	[625]	[587,592,515,582]	-4	hSpCas9	negative selection	5633477
224446	224469	5	-	27260156	BXPC3	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.2629797837306321	[574]	[486,445,519,559]	-5	hSpCas9	negative selection	5633478
226021	226044	5	+	27260156	BXPC3	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.23200015617396075	[690]	[864,684,915,942]	5	hSpCas9	negative selection	5633479
225549	225572	5	-	27260156	A673	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.31692976645970683	[258]	[296,507,278,455]	7	hSpCas9	negative selection	5690474
226034	226057	5	-	27260156	A673	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.38483687656349164	[236]	[414,355,350,368]	8	hSpCas9	negative selection	5690475
224423	224446	5	+	27260156	A673	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.17145293010466656	[1204]	[1554,1495,1632,1836]	4	hSpCas9	negative selection	5690476
225523	225546	5	-	27260156	A673	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.04660537039472479	[625]	[900,622,691,715]	-1	hSpCas9	negative selection	5754728
224446	224469	5	-	27260156	A673	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.02889188345610988	[574]	[744,648,635,684]	0	hSpCas9	negative selection	5754729
226021	226044	5	+	27260156	A673	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.2022147468456469	[690]	[859,959,1022,961]	5	hSpCas9	negative selection	5754730
225549	225572	5	-	27260156	A375	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.9161238104961438	[258]	[40,63,106,102]	-9	hSpCas9	negative selection	5811725
226034	226057	5	-	27260156	A375	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.11898164495310748	[236]	[223,407,193,379]	1	hSpCas9	negative selection	5811726
224423	224446	5	+	27260156	A375	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.5716552119050575	[1204]	[1891,2403,2291,1842]	8	hSpCas9	negative selection	5811727
225523	225546	5	-	27260156	A375	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.6830340769518901	[625]	[167,435,194,148]	-9	hSpCas9	negative selection	5875979
224446	224469	5	-	27260156	A375	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-1.0885149659233955	[574]	[335,342,363,232]	-8	hSpCas9	negative selection	5875980
226021	226044	5	+	27260156	A375	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.663230735543568	[690]	[1261,1638,945,1306]	8	hSpCas9	negative selection	5875981
225549	225572	5	-	27260156	COLO741	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.1598572452049678	[258]	[260,298,322]	-3	hSpCas9	negative selection	5932976
226034	226057	5	-	27260156	COLO741	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.3439020897079704	[236]	[309,437,396]	7	hSpCas9	negative selection	5932977
224423	224446	5	+	27260156	COLO741	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	-0.08041579085961414	[1204]	[1495,1436,1436]	-2	hSpCas9	negative selection	5932978
225523	225546	5	-	27260156	COLO741	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.6359024679841282	[625]	[653,405,495]	-8	hSpCas9	negative selection	5997230
224446	224469	5	-	27260156	COLO741	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.11881286703806807	[574]	[850,560,633]	-3	hSpCas9	negative selection	5997231
226021	226044	5	+	27260156	COLO741	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.18017825443058277	[690]	[1037,978,985]	4	hSpCas9	negative selection	5997232
225549	225572	5	-	27260156	CAL120	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.241048154628964	[258]	[184,132,98]	-9	hSpCas9	negative selection	6054227
226034	226057	5	-	27260156	CAL120	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.5416286697414461	[236]	[693,342,292]	7	hSpCas9	negative selection	6054228
224423	224446	5	+	27260156	CAL120	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.3562472865717805	[1204]	[2444,1711,1683]	5	hSpCas9	negative selection	6054229
225523	225546	5	-	27260156	CAL120	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.6135648265780864	[625]	[523,528,476]	-7	hSpCas9	negative selection	6118481
224446	224469	5	-	27260156	CAL120	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.1379398506414014	[574]	[1004,519,481]	-2	hSpCas9	negative selection	6118482
226021	226044	5	+	27260156	CAL120	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.38626126574069153	[690]	[1121,743,1497]	6	hSpCas9	negative selection	6118483
225549	225572	5	-	27260156	CADOES1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.6864234373346343	[258]	[130,133,202,129]	-8	hSpCas9	negative selection	6175478
226034	226057	5	-	27260156	CADOES1	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.7655678221789988	[236]	[243,396,413,446]	9	hSpCas9	negative selection	6175479
224423	224446	5	+	27260156	CADOES1	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.24605184224787235	[1204]	[1415,1232,1339,1326]	4	hSpCas9	negative selection	6175480
225523	225546	5	-	27260156	CADOES1	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.8696484825412772	[625]	[351,274,337,308]	-9	hSpCas9	negative selection	6239732
224446	224469	5	-	27260156	CADOES1	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.4595282129642978	[574]	[337,365,454,396]	-7	hSpCas9	negative selection	6239733
226021	226044	5	+	27260156	CADOES1	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.29837424461133344	[690]	[709,839,785,826]	5	hSpCas9	negative selection	6239734
225549	225572	5	-	27260156	EWS502	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.24648555586554222	[258]	[381,358,221,327]	4	hSpCas9	negative selection	6296729
226034	226057	5	-	27260156	EWS502	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.7589191601250644	[236]	[355,499,417,428]	9	hSpCas9	negative selection	6296730
224423	224446	5	+	27260156	EWS502	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.12202677359628988	[1204]	[1725,1162,1168,1462]	2	hSpCas9	negative selection	6296731
225523	225546	5	-	27260156	EWS502	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.33217460670402066	[625]	[500,484,444,688]	-5	hSpCas9	negative selection	6360983
224446	224469	5	-	27260156	EWS502	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.07050849815543905	[574]	[544,607,633,530]	-1	hSpCas9	negative selection	6360984
226021	226044	5	+	27260156	EWS502	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.44466008667208734	[690]	[954,747,1137,1168]	7	hSpCas9	negative selection	6360985
225549	225572	5	-	27260156	EW8	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.3688623748259767	[258]	[66,183,228,147]	-6	hSpCas9	negative selection	6417980
226034	226057	5	-	27260156	EW8	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.3875302881384125	[236]	[359,323,191,150]	7	hSpCas9	negative selection	6417981
224423	224446	5	+	27260156	EW8	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.28291924942455493	[1204]	[1362,1344,887,1223]	5	hSpCas9	negative selection	6417982
225523	225546	5	-	27260156	EW8	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.377696596898044	[625]	[576,321,319,373]	-6	hSpCas9	negative selection	6482234
224446	224469	5	-	27260156	EW8	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.31987768358026936	[574]	[472,480,236,335]	-5	hSpCas9	negative selection	6482235
226021	226044	5	+	27260156	EW8	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.30145924607102426	[690]	[723,577,686,772]	5	hSpCas9	negative selection	6482236
225549	225572	5	-	27260156	CORL105	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.13945258311726283	[258]	[143,187,335,438]	-3	hSpCas9	negative selection	6539231
226034	226057	5	-	27260156	CORL105	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	-0.021520284010698942	[236]	[357,161,302,279]	0	hSpCas9	negative selection	6539232
224423	224446	5	+	27260156	CORL105	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.05602237222217754	[1204]	[1470,1315,1615,1488]	1	hSpCas9	negative selection	6539233
225523	225546	5	-	27260156	CORL105	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.9198670908817821	[625]	[388,355,425,384]	-9	hSpCas9	negative selection	6603485
224446	224469	5	-	27260156	CORL105	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.7170074758012882	[574]	[348,422,525,355]	-8	hSpCas9	negative selection	6603486
226021	226044	5	+	27260156	CORL105	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.4373499827600761	[690]	[1126,1019,1347,928]	7	hSpCas9	negative selection	6603487
225549	225572	5	-	27260156	HS294T	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.9919724876411409	[258]	[30,27,83,62]	-8	hSpCas9	negative selection	6660482
226034	226057	5	-	27260156	HS294T	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.09697339255925386	[236]	[107,89,89,103]	1	hSpCas9	negative selection	6660483
224423	224446	5	+	27260156	HS294T	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.3127871530276023	[1204]	[454,709,518,647]	4	hSpCas9	negative selection	6660484
225523	225546	5	-	27260156	HS294T	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.197808646471448	[625]	[63,95,120,152]	-9	hSpCas9	negative selection	6724736
224446	224469	5	-	27260156	HS294T	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-1.0252131196143814	[574]	[65,77,107,205]	-9	hSpCas9	negative selection	6724737
226021	226044	5	+	27260156	HS294T	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.3592250034793062	[690]	[367,239,393,373]	5	hSpCas9	negative selection	6724738
225549	225572	5	-	27260156	HCC44	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.0537726078075247	[258]	[145,38,227,178]	-8	hSpCas9	negative selection	6781733
226034	226057	5	-	27260156	HCC44	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.11550545216298647	[236]	[263,243,390,281]	1	hSpCas9	negative selection	6781734
224423	224446	5	+	27260156	HCC44	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.40620963654245257	[1204]	[2293,1495,2184,1401]	6	hSpCas9	negative selection	6781735
225523	225546	5	-	27260156	HCC44	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.1105287557615684	[625]	[361,263,393,312]	-8	hSpCas9	negative selection	6845987
224446	224469	5	-	27260156	HCC44	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.5362392468278799	[574]	[519,338,596,383]	-7	hSpCas9	negative selection	6845988
226021	226044	5	+	27260156	HCC44	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.3724664244233461	[690]	[769,871,1330,1114]	6	hSpCas9	negative selection	6845989
225549	225572	5	-	27260156	G402	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-2.664037362681462	[258]	[36,138,27,0]	-9	hSpCas9	negative selection	6902984
226034	226057	5	-	27260156	G402	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.9106664088825337	[236]	[496,616,702,361]	9	hSpCas9	negative selection	6902985
224423	224446	5	+	27260156	G402	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.36447886963381615	[1204]	[1874,3281,919,1580]	4	hSpCas9	negative selection	6902986
225523	225546	5	-	27260156	G402	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.512812109590965	[625]	[335,326,258,165]	-9	hSpCas9	negative selection	6967238
224446	224469	5	-	27260156	G402	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-1.0713587242855085	[574]	[275,198,423,414]	-8	hSpCas9	negative selection	6967239
226021	226044	5	+	27260156	G402	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.15993703694094186	[690]	[1044,970,675,1081]	2	hSpCas9	negative selection	6967240
225549	225572	5	-	27260156	L33	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.2969530095898332	[258]	[250,87,122,180]	-6	hSpCas9	negative selection	7024235
226034	226057	5	-	27260156	L33	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.24854235773803912	[236]	[197,85,224,361]	5	hSpCas9	negative selection	7024236
224423	224446	5	+	27260156	L33	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.12705959600945582	[1204]	[1423,516,854,1215]	3	hSpCas9	negative selection	7024237
225523	225546	5	-	27260156	L33	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.300988236236939	[625]	[454,203,365,498]	-6	hSpCas9	negative selection	7088489
224446	224469	5	-	27260156	L33	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.17592517170570132	[574]	[531,190,361,461]	-4	hSpCas9	negative selection	7088490
226021	226044	5	+	27260156	L33	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.08943443798859019	[690]	[739,288,526,657]	2	hSpCas9	negative selection	7088491
225549	225572	5	-	27260156	K562	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-2.0471796197915273	[258]	[15,120,25,58]	-9	hSpCas9	negative selection	7145486
226034	226057	5	-	27260156	K562	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	1.21384898804991	[236]	[645,548,513,280]	9	hSpCas9	negative selection	7145487
224423	224446	5	+	27260156	K562	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.5515121266350962	[1204]	[1276,1813,1342,1790]	7	hSpCas9	negative selection	7145488
225523	225546	5	-	27260156	K562	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.273268449579836	[625]	[190,252,219,249]	-8	hSpCas9	negative selection	7209740
224446	224469	5	-	27260156	K562	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.09031075010576112	[574]	[656,448,350,471]	-1	hSpCas9	negative selection	7209741
226021	226044	5	+	27260156	K562	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.5318883209864875	[690]	[1084,877,808,796]	6	hSpCas9	negative selection	7209742
225549	225572	5	-	27260156	HT29	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.20817887004790037	[258]	[257,351,382,119]	-4	hSpCas9	negative selection	7266737
226034	226057	5	-	27260156	HT29	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.5875135955629264	[236]	[382,445,411,478]	9	hSpCas9	negative selection	7266738
224423	224446	5	+	27260156	HT29	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.28999397547049743	[1204]	[2161,1858,1749,1455]	5	hSpCas9	negative selection	7266739
225523	225546	5	-	27260156	HT29	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.371975306551302	[625]	[807,562,595,416]	-6	hSpCas9	negative selection	7330991
224446	224469	5	-	27260156	HT29	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.2875492705153506	[574]	[665,640,495,504]	-5	hSpCas9	negative selection	7330992
226021	226044	5	+	27260156	HT29	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.37620929070279896	[690]	[1024,1120,1036,1158]	7	hSpCas9	negative selection	7330993
225549	225572	5	-	27260156	MHHES1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.40375729562026297	[258]	[508,500,215,343]	7	hSpCas9	negative selection	7387988
226034	226057	5	-	27260156	MHHES1	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.35989324315766535	[236]	[380,346,427,236]	6	hSpCas9	negative selection	7387989
224423	224446	5	+	27260156	MHHES1	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.1258875830498587	[1204]	[1546,1235,1477,1585]	2	hSpCas9	negative selection	7387990
225523	225546	5	-	27260156	MHHES1	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.2280668030604914	[625]	[790,521,478,612]	-4	hSpCas9	negative selection	7452242
224446	224469	5	-	27260156	MHHES1	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.21429345703861413	[574]	[1088,723,485,729]	4	hSpCas9	negative selection	7452243
226021	226044	5	+	27260156	MHHES1	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.3545898777093529	[690]	[1251,1186,753,847]	6	hSpCas9	negative selection	7452244
225549	225572	5	-	27260156	MEWO	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.2061341965238872	[258]	[302,231,112]	-4	hSpCas9	negative selection	7509239
226034	226057	5	-	27260156	MEWO	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.3064631457600343	[236]	[307,294,225]	6	hSpCas9	negative selection	7509240
224423	224446	5	+	27260156	MEWO	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.08303163302156569	[1204]	[1373,1192,1049]	1	hSpCas9	negative selection	7509241
225523	225546	5	-	27260156	MEWO	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.05758446883468238	[625]	[540,541,600]	-1	hSpCas9	negative selection	7573493
224446	224469	5	-	27260156	MEWO	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.05150799928576422	[574]	[656,486,547]	1	hSpCas9	negative selection	7573494
226021	226044	5	+	27260156	MEWO	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	-0.013131407977516885	[690]	[775,421,750]	0	hSpCas9	negative selection	7573495
225549	225572	5	-	27260156	LNCAPCLONEFGC	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.2204551995949342	[258]	[129,55,133,89]	-9	hSpCas9	negative selection	7630490
226034	226057	5	-	27260156	LNCAPCLONEFGC	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.6158618585835616	[236]	[302,254,475,308]	8	hSpCas9	negative selection	7630491
224423	224446	5	+	27260156	LNCAPCLONEFGC	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.16560143827424967	[1204]	[1098,1087,1453,1300]	2	hSpCas9	negative selection	7630492
225523	225546	5	-	27260156	LNCAPCLONEFGC	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.022287744277801	[625]	[259,239,396,239]	-9	hSpCas9	negative selection	7694744
224446	224469	5	-	27260156	LNCAPCLONEFGC	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.5356118536809718	[574]	[354,233,416,447]	-7	hSpCas9	negative selection	7694745
226021	226044	5	+	27260156	LNCAPCLONEFGC	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.4265259838388341	[690]	[745,1006,959,659]	6	hSpCas9	negative selection	7694746
225549	225572	5	-	27260156	PANC0327	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.6857583111555279	[258]	[152,76,42,18]	-9	hSpCas9	negative selection	7751741
226034	226057	5	-	27260156	PANC0327	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.08504393793822895	[236]	[244,130,298,231]	1	hSpCas9	negative selection	7751742
224423	224446	5	+	27260156	PANC0327	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.24956066246070807	[1204]	[1546,1142,1218,1219]	3	hSpCas9	negative selection	7751743
225523	225546	5	-	27260156	PANC0327	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.6791426782080819	[625]	[228,394,274,473]	-7	hSpCas9	negative selection	7815995
224446	224469	5	-	27260156	PANC0327	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.5671066449177452	[574]	[263,330,333,444]	-7	hSpCas9	negative selection	7815996
226021	226044	5	+	27260156	PANC0327	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.22943916255564956	[690]	[699,652,619,911]	3	hSpCas9	negative selection	7815997
225549	225572	5	-	27260156	NCIH2009	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.7746435466595696	[258]	[234,202,200]	-7	hSpCas9	negative selection	7872992
226034	226057	5	-	27260156	NCIH2009	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.2482517770262661	[236]	[352,352,465]	3	hSpCas9	negative selection	7872993
224423	224446	5	+	27260156	NCIH2009	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.34977297780172445	[1204]	[2486,2161,1850]	5	hSpCas9	negative selection	7872994
225523	225546	5	-	27260156	NCIH2009	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-1.019906013222803	[625]	[485,487,328]	-8	hSpCas9	negative selection	7937246
224446	224469	5	-	27260156	NCIH2009	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.0762937405572677	[574]	[884,980,438]	-1	hSpCas9	negative selection	7937247
226021	226044	5	+	27260156	NCIH2009	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.1675080849785937	[690]	[934,1113,1171]	2	hSpCas9	negative selection	7937248
225549	225572	5	-	27260156	NCIH1373	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.4717057542089456	[258]	[71,81,27,63]	-9	hSpCas9	negative selection	7994243
226034	226057	5	-	27260156	NCIH1373	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.7910368334787978	[236]	[390,155,723,154]	7	hSpCas9	negative selection	7994244
224423	224446	5	+	27260156	NCIH1373	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.7497051266157548	[1204]	[3053,1647,1867,716]	7	hSpCas9	negative selection	7994245
225523	225546	5	-	27260156	NCIH1373	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.5737057543043677	[625]	[994,324,334,83]	-5	hSpCas9	negative selection	8058497
224446	224469	5	-	27260156	NCIH1373	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.2653800572995897	[574]	[738,427,468,144]	-3	hSpCas9	negative selection	8058498
226021	226044	5	+	27260156	NCIH1373	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.8779181420851556	[690]	[1474,1730,1584,217]	8	hSpCas9	negative selection	8058499
225549	225572	5	-	27260156	PATU8902	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.5848971765813977	[258]	[89,485,193,199]	-5	hSpCas9	negative selection	8115494
226034	226057	5	-	27260156	PATU8902	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.1524061741661774	[236]	[530,449,269,218]	1	hSpCas9	negative selection	8115495
224423	224446	5	+	27260156	PATU8902	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.8955005785645387	[1204]	[2942,4639,1871,3368]	8	hSpCas9	negative selection	8115496
225523	225546	5	-	27260156	PATU8902	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.9921926913335921	[625]	[646,378,218,574]	-7	hSpCas9	negative selection	8179748
224446	224469	5	-	27260156	PATU8902	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.523283060146243	[574]	[669,583,503,467]	-5	hSpCas9	negative selection	8179749
226021	226044	5	+	27260156	PATU8902	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.7392677911720025	[690]	[1909,1887,1040,1732]	7	hSpCas9	negative selection	8179750
225549	225572	5	-	27260156	PANC1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.5058456646129839	[258]	[248,397,448,200]	7	hSpCas9	negative selection	8236745
226034	226057	5	-	27260156	PANC1	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	-0.07973597257126586	[236]	[151,229,221,174]	-1	hSpCas9	negative selection	8236746
224423	224446	5	+	27260156	PANC1	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.19709847199004682	[1204]	[1270,1444,1059,1026]	3	hSpCas9	negative selection	8236747
225523	225546	5	-	27260156	PANC1	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	0.04247698048263815	[625]	[422,892,479,491]	0	hSpCas9	negative selection	8300999
224446	224469	5	-	27260156	PANC1	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.23254344292653636	[574]	[369,518,541,287]	-4	hSpCas9	negative selection	8301000
226021	226044	5	+	27260156	PANC1	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.31218167197109536	[690]	[686,1164,824,403]	5	hSpCas9	negative selection	8301001
225549	225572	5	-	27260156	PANC0813	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.05487142935289335	[258]	[324,278,243,323]	-1	hSpCas9	negative selection	8357996
226034	226057	5	-	27260156	PANC0813	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.12218234845632825	[236]	[418,244,254,302]	2	hSpCas9	negative selection	8357997
224423	224446	5	+	27260156	PANC0813	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.3083554859780777	[1204]	[2054,1660,1752,1576]	5	hSpCas9	negative selection	8357998
225523	225546	5	-	27260156	PANC0813	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.8055864642042299	[625]	[405,349,483,439]	-8	hSpCas9	negative selection	8422250
224446	224469	5	-	27260156	PANC0813	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.18654120854533532	[574]	[428,763,646,521]	-3	hSpCas9	negative selection	8422251
226021	226044	5	+	27260156	PANC0813	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.12736650604906175	[690]	[804,988,1059,694]	2	hSpCas9	negative selection	8422252
225549	225572	5	-	27260156	RDES	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.28632756037996676	[258]	[335,328,296,507]	4	hSpCas9	negative selection	8479247
226034	226057	5	-	27260156	RDES	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.8072559658593876	[236]	[535,347,467,548]	9	hSpCas9	negative selection	8479248
224423	224446	5	+	27260156	RDES	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.3094416970482301	[1204]	[1415,1521,1913,2117]	5	hSpCas9	negative selection	8479249
225523	225546	5	-	27260156	RDES	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.3841929453066246	[625]	[534,529,498,640]	-6	hSpCas9	negative selection	8543501
224446	224469	5	-	27260156	RDES	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	0.12751631244219425	[574]	[654,822,562,840]	2	hSpCas9	negative selection	8543502
226021	226044	5	+	27260156	RDES	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.5622154099618377	[690]	[996,986,1363,1408]	8	hSpCas9	negative selection	8543503
225549	225572	5	-	27260156	PC3	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.34516674174953477	[258]	[155,170,331,202]	-7	hSpCas9	negative selection	8600498
226034	226057	5	-	27260156	PC3	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.10965944312545928	[236]	[182,236,427,242]	2	hSpCas9	negative selection	8600499
224423	224446	5	+	27260156	PC3	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.01720411861647797	[1204]	[837,1050,1918,1381]	0	hSpCas9	negative selection	8600500
225523	225546	5	-	27260156	PC3	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.39391533775221327	[625]	[386,402,810,410]	-7	hSpCas9	negative selection	8664752
224446	224469	5	-	27260156	PC3	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.1440351685525069	[574]	[395,534,824,425]	-3	hSpCas9	negative selection	8664753
226021	226044	5	+	27260156	PC3	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.18485867161260228	[690]	[470,841,1230,822]	4	hSpCas9	negative selection	8664754
225549	225572	5	-	27260156	PATU8988T	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.7213662156362644	[258]	[184,154,144,119]	-8	hSpCas9	negative selection	8721749
226034	226057	5	-	27260156	PATU8988T	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.36638518424349986	[236]	[214,305,343,317]	6	hSpCas9	negative selection	8721750
224423	224446	5	+	27260156	PATU8988T	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.05675727638703343	[1204]	[1223,1300,1214,1103]	1	hSpCas9	negative selection	8721751
225523	225546	5	-	27260156	PATU8988T	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.8262860833442323	[625]	[437,407,165,362]	-8	hSpCas9	negative selection	8786003
224446	224469	5	-	27260156	PATU8988T	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.29937076847021915	[574]	[473,427,437,464]	-5	hSpCas9	negative selection	8786004
226021	226044	5	+	27260156	PATU8988T	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.23559621695380584	[690]	[879,740,772,742]	4	hSpCas9	negative selection	8786005
225549	225572	5	-	27260156	T47D	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-1.0389806943174795	[258]	[180,159,120,123]	-9	hSpCas9	negative selection	8843000
226034	226057	5	-	27260156	T47D	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.3646463421510975	[236]	[418,266,333,411]	7	hSpCas9	negative selection	8843001
224423	224446	5	+	27260156	T47D	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.13989664933610002	[1204]	[1555,1282,1640,1733]	3	hSpCas9	negative selection	8843002
225523	225546	5	-	27260156	T47D	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.5196799416897416	[625]	[550,453,449,587]	-8	hSpCas9	negative selection	8907254
224446	224469	5	-	27260156	T47D	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.4993505952217511	[574]	[532,428,436,501]	-8	hSpCas9	negative selection	8907255
226021	226044	5	+	27260156	T47D	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.27274254853380064	[690]	[958,984,842,1107]	6	hSpCas9	negative selection	8907256
225549	225572	5	-	27260156	SU8686	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.06538566131219614	[258]	[258,230,300,179]	-1	hSpCas9	negative selection	8964251
226034	226057	5	-	27260156	SU8686	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.3155560266100965	[236]	[231,257,323,379]	5	hSpCas9	negative selection	8964252
224423	224446	5	+	27260156	SU8686	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.2824433178866341	[1204]	[1356,1134,1627,1793]	5	hSpCas9	negative selection	8964253
225523	225546	5	-	27260156	SU8686	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.44903623707818896	[625]	[467,446,402,502]	-6	hSpCas9	negative selection	9028505
224446	224469	5	-	27260156	SU8686	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.04832625951756822	[574]	[561,490,524,643]	-1	hSpCas9	negative selection	9028506
226021	226044	5	+	27260156	SU8686	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.4719721312412346	[690]	[846,875,1045,1067]	7	hSpCas9	negative selection	9028507
225549	225572	5	-	27260156	SKES1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.34675122451980966	[258]	[322,174,156,172]	-6	hSpCas9	negative selection	9085502
226034	226057	5	-	27260156	SKES1	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.14843405423684064	[236]	[262,316,316,165]	3	hSpCas9	negative selection	9085503
224423	224446	5	+	27260156	SKES1	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.17494256813056963	[1204]	[1607,1500,1197,1181]	4	hSpCas9	negative selection	9085504
225523	225546	5	-	27260156	SKES1	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.4974423955738973	[625]	[542,470,372,400]	-8	hSpCas9	negative selection	9149756
224446	224469	5	-	27260156	SKES1	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.3212626153555955	[574]	[531,444,512,360]	-6	hSpCas9	negative selection	9149757
226021	226044	5	+	27260156	SKES1	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.26216247524140235	[690]	[989,990,690,686]	5	hSpCas9	negative selection	9149758
225549	225572	5	-	27260156	TOV112D	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.07975625983545931	[258]	[290,259,162,273]	-1	hSpCas9	negative selection	9206753
226034	226057	5	-	27260156	TOV112D	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.123726446719711	[236]	[314,330,201,209]	2	hSpCas9	negative selection	9206754
224423	224446	5	+	27260156	TOV112D	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.33612814816958125	[1204]	[1592,1975,1452,1195]	6	hSpCas9	negative selection	9206755
225523	225546	5	-	27260156	TOV112D	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.6836130539659705	[625]	[321,529,441,297]	-8	hSpCas9	negative selection	9271007
224446	224469	5	-	27260156	TOV112D	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.7420580307160056	[574]	[289,542,387,203]	-9	hSpCas9	negative selection	9271008
226021	226044	5	+	27260156	TOV112D	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	-0.04926018365145712	[690]	[695,786,603,619]	-1	hSpCas9	negative selection	9271009
225549	225572	5	-	27260156	TC71	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.10702612871110839	[258]	[347,230,299,316]	2	hSpCas9	negative selection	9328004
226034	226057	5	-	27260156	TC71	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.31066520094675076	[236]	[254,342,303,362]	7	hSpCas9	negative selection	9328005
224423	224446	5	+	27260156	TC71	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	-0.019485124715401758	[1204]	[1229,1382,1096,1401]	0	hSpCas9	negative selection	9328006
225523	225546	5	-	27260156	TC71	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.1936086487664768	[625]	[509,562,580,701]	-5	hSpCas9	negative selection	9392258
224446	224469	5	-	27260156	TC71	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.05464219352312763	[574]	[572,656,557,586]	-1	hSpCas9	negative selection	9392259
226021	226044	5	+	27260156	TC71	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.1460826113729996	[690]	[763,879,764,875]	3	hSpCas9	negative selection	9392260
225549	225572	5	-	27260156	TC32	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	0.31880264469567177	[258]	[223,255,306,445]	5	hSpCas9	negative selection	9449255
226034	226057	5	-	27260156	TC32	viability	CGGCCTTACCCTTCCATATAAGG	SDHA	ENSG00000073578	0.5866524299258234	[236]	[373,202,398,401]	8	hSpCas9	negative selection	9449256
224423	224446	5	+	27260156	TC32	viability	GCAGGCTTGCGAGCTGCATTTGG	SDHA	ENSG00000073578	0.18791932032289793	[1204]	[1171,950,1690,1493]	3	hSpCas9	negative selection	9449257
225523	225546	5	-	27260156	TC32	viability	GGGCCTGCTCCGTCATGTAGTGG	SDHA	ENSG00000073578	-0.4874359282870608	[625]	[410,213,669,486]	-7	hSpCas9	negative selection	9513509
224446	224469	5	-	27260156	TC32	viability	TATTAAACCCTGCCTCAGAAAGG	SDHA	ENSG00000073578	-0.47508451086678205	[574]	[357,233,562,475]	-7	hSpCas9	negative selection	9513510
226021	226044	5	+	27260156	TC32	viability	TCGCTATTGCACACCTTATATGG	SDHA	ENSG00000073578	0.33697767886182517	[690]	[689,758,1087,775]	6	hSpCas9	negative selection	9513511
220236	220259	5	-	27869803	HPAFII	viability after 27 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-1.2964025900996996	[109]	[40,8,NaN]	-7	hSpCas9	negative selection	9591655
225545	225568	5	-	27869803	HPAFII	viability after 27 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.16594383262393464	[83]	[36,59,NaN]	1	hSpCas9	negative selection	9591657
235209	235232	5	-	27869803	HPAFII	viability after 27 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.6659237826112552	[230]	[34,40,NaN]	-8	hSpCas9	negative selection	9591658
220236	220259	5	-	27869803	HPAFII	viability after 15 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-0.8101808832393778	[109]	[125,30,NaN]	-7	hSpCas9	negative selection	9674104
225545	225568	5	-	27869803	HPAFII	viability after 15 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.05367052533929928	[83]	[57,104,NaN]	0	hSpCas9	negative selection	9674106
235209	235232	5	-	27869803	HPAFII	viability after 15 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-2.270956122138015	[230]	[101,19,NaN]	-9	hSpCas9	negative selection	9674107
220236	220259	5	-	27869803	ASPC1	viability after 36 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	1.1378740362566238	[179]	[20,349,50]	9	hSpCas9	negative selection	9756553
225545	225568	5	-	27869803	ASPC1	viability after 36 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.8897724683593793	[229]	[56,83,0]	-7	hSpCas9	negative selection	9756555
235209	235232	5	-	27869803	ASPC1	viability after 36 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.0144490571393414	[827]	[110,185,129]	-7	hSpCas9	negative selection	9756556
220236	220259	5	-	27869803	PATU8988S	viability after 35 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.09062116315855584	[140]	[46,73,NaN]	1	hSpCas9	negative selection	9839002
225545	225568	5	-	27869803	PATU8988S	viability after 35 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-0.07314180807565052	[208]	[85,73,NaN]	0	hSpCas9	negative selection	9839004
235209	235232	5	-	27869803	PATU8988S	viability after 35 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.4157585122043344	[585]	[70,105,NaN]	-8	hSpCas9	negative selection	9839005
220236	220259	5	-	27869803	PATU8988S	viability after 31 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	0.040660338972346555	[140]	[8,119,NaN]	0	hSpCas9	negative selection	9921451
225545	225568	5	-	27869803	PATU8988S	viability after 31 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.33110857360087187	[208]	[88,124,NaN]	4	hSpCas9	negative selection	9921453
235209	235232	5	-	27869803	PATU8988S	viability after 31 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-1.552919284107044	[585]	[65,96,NaN]	-8	hSpCas9	negative selection	9921454
220236	220259	5	-	27869803	HPAFII	viability after 35 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-2.9676822693160183	[109]	[8,4,NaN]	-8	hSpCas9	negative selection	10003900
225545	225568	5	-	27869803	HPAFII	viability after 35 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	0.2201066098946587	[83]	[57,39,NaN]	1	hSpCas9	negative selection	10003902
235209	235232	5	-	27869803	HPAFII	viability after 35 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-2.631369045303219	[230]	[0,38,NaN]	-8	hSpCas9	negative selection	10003903
220236	220259	5	-	27869803	HPAFII	viability after 31 days	TGCAAGCTGTGTCAGTGCACTGG	SDHA	ENSG00000073578	-3.438835616803896	[109]	[9,0,NaN]	-9	hSpCas9	negative selection	10086349
225545	225568	5	-	27869803	HPAFII	viability after 31 days	ATCACCTCGACCACGGCGGCGGG	SDHA	ENSG00000073578	-1.3444883215762684	[83]	[19,16,NaN]	-7	hSpCas9	negative selection	10086351
235209	235232	5	-	27869803	HPAFII	viability after 31 days	TGAAATGCCAGGCAGGCGCGTGG	SDHA	ENSG00000073578	-2.705235665354159	[230]	[5,34,NaN]	-8	hSpCas9	negative selection	10086352
230990	231013	5	-	28162770	P31FUJ	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-2.405638801276594	[247]	[54]	-8	hSpCas9	negative selection	10231101
251435	251458	5	+	28162770	P31FUJ	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.2980936646660979	[112]	[53]	-7	hSpCas9	negative selection	10231102
233565	233588	5	+	28162770	P31FUJ	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.1173249869944426	[83]	[90]	-1	hSpCas9	negative selection	10231103
236498	236521	5	-	28162770	P31FUJ	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.2714826725784385	[188]	[22]	-9	hSpCas9	negative selection	10231104
225514	225537	5	+	28162770	P31FUJ	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.560489568590426	[250]	[49]	-8	hSpCas9	negative selection	10231105
225549	225572	5	-	28162770	P31FUJ	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-4.554730299301741	[99]	[4]	-9	hSpCas9	negative selection	10231106
230910	230933	5	+	28162770	P31FUJ	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-3.24987571777332	[169]	[20]	-9	hSpCas9	negative selection	10231107
235314	235337	5	+	28162770	P31FUJ	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.6750245330194526	[249]	[45]	-9	hSpCas9	negative selection	10231108
218367	218390	5	-	28162770	P31FUJ	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.40042126512459286	[546]	[486]	-4	hSpCas9	negative selection	10231109
235292	235315	5	+	28162770	P31FUJ	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.3031915323057763	[293]	[34]	-9	hSpCas9	negative selection	10231110
230990	231013	5	-	28162770	TF1	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10400467
251435	251458	5	+	28162770	TF1	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10400468
233565	233588	5	+	28162770	TF1	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10400469
236498	236521	5	-	28162770	TF1	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10400470
225514	225537	5	+	28162770	TF1	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10400471
225549	225572	5	-	28162770	TF1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10400472
230910	230933	5	+	28162770	TF1	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10400473
235314	235337	5	+	28162770	TF1	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10400474
218367	218390	5	-	28162770	TF1	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10400475
235292	235315	5	+	28162770	TF1	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10400476
230990	231013	5	-	28162770	SKM1	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.8808953870755738	[74]	[71]	-6	hSpCas9	negative selection	10569833
251435	251458	5	+	28162770	SKM1	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10569834
233565	233588	5	+	28162770	SKM1	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.11386796455827897	[22]	[43]	1	hSpCas9	negative selection	10569835
236498	236521	5	-	28162770	SKM1	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.8220016980220053	[47]	[5]	-9	hSpCas9	negative selection	10569836
225514	225537	5	+	28162770	SKM1	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.7985427251980164	[60]	[30]	-8	hSpCas9	negative selection	10569837
225549	225572	5	-	28162770	SKM1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-3.2005133212757357	[25]	[4]	-9	hSpCas9	negative selection	10569838
230910	230933	5	+	28162770	SKM1	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10569839
235314	235337	5	+	28162770	SKM1	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-3.709526968763593	[73]	[9]	-9	hSpCas9	negative selection	10569840
218367	218390	5	-	28162770	SKM1	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.39176179209949147	[117]	[158]	-3	hSpCas9	negative selection	10569841
235292	235315	5	+	28162770	SKM1	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.0648582219181693	[70]	[14]	-9	hSpCas9	negative selection	10569842
230990	231013	5	-	28162770	SKM1	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.8808953870755738	[74]	[71]	-6	hSpCas9	negative selection	10739199
251435	251458	5	+	28162770	SKM1	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-0.2914869813232256	[35]	[51]	-2	hSpCas9	negative selection	10739200
233565	233588	5	+	28162770	SKM1	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.11386796455827897	[22]	[43]	1	hSpCas9	negative selection	10739201
236498	236521	5	-	28162770	SKM1	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.8220016980220053	[47]	[5]	-9	hSpCas9	negative selection	10739202
225514	225537	5	+	28162770	SKM1	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.7985427251980164	[60]	[30]	-8	hSpCas9	negative selection	10739203
225549	225572	5	-	28162770	SKM1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-3.2005133212757357	[25]	[4]	-9	hSpCas9	negative selection	10739204
230910	230933	5	+	28162770	SKM1	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.1532076064973786	[38]	[30]	-7	hSpCas9	negative selection	10739205
235314	235337	5	+	28162770	SKM1	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-3.709526968763593	[73]	[9]	-9	hSpCas9	negative selection	10739206
218367	218390	5	-	28162770	SKM1	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.39176179209949147	[117]	[158]	-3	hSpCas9	negative selection	10739207
235292	235315	5	+	28162770	SKM1	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.0648582219181693	[70]	[14]	-9	hSpCas9	negative selection	10739208
230990	231013	5	-	28162770	PL21	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	0.18454275943830145	[278]	[137]	1	hSpCas9	negative selection	10908565
251435	251458	5	+	28162770	PL21	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.829607728904732	[97]	[11]	-8	hSpCas9	negative selection	10908566
233565	233588	5	+	28162770	PL21	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.05996195644105984	[107]	[48]	0	hSpCas9	negative selection	10908567
236498	236521	5	-	28162770	PL21	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-6.057248228203332	[152]	[0]	-9	hSpCas9	negative selection	10908568
225514	225537	5	+	28162770	PL21	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.915337602930616	[311]	[35]	-8	hSpCas9	negative selection	10908569
225549	225572	5	-	28162770	PL21	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-5.399773227697808	[96]	[0]	-9	hSpCas9	negative selection	10908570
230910	230933	5	+	28162770	PL21	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.9910018728626877	[136]	[14]	-8	hSpCas9	negative selection	10908571
235314	235337	5	+	28162770	PL21	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.825395477617817	[227]	[13]	-9	hSpCas9	negative selection	10908572
218367	218390	5	-	28162770	PL21	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.41263473624950475	[418]	[136]	-3	hSpCas9	negative selection	10908573
235292	235315	5	+	28162770	PL21	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-1.12916801076364	[195]	[38]	-6	hSpCas9	negative selection	10908574
230990	231013	5	-	28162770	P31FUJ	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-2.405638801276594	[247]	[54]	-8	hSpCas9	negative selection	11077931
251435	251458	5	+	28162770	P31FUJ	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.2980936646660979	[112]	[53]	-7	hSpCas9	negative selection	11077932
233565	233588	5	+	28162770	P31FUJ	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.1173249869944426	[83]	[90]	-1	hSpCas9	negative selection	11077933
236498	236521	5	-	28162770	P31FUJ	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.2714826725784385	[188]	[22]	-9	hSpCas9	negative selection	11077934
225514	225537	5	+	28162770	P31FUJ	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.560489568590426	[250]	[49]	-8	hSpCas9	negative selection	11077935
225549	225572	5	-	28162770	P31FUJ	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-4.554730299301741	[99]	[4]	-9	hSpCas9	negative selection	11077936
230910	230933	5	+	28162770	P31FUJ	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-3.24987571777332	[169]	[20]	-9	hSpCas9	negative selection	11077937
235314	235337	5	+	28162770	P31FUJ	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.6750245330194526	[249]	[45]	-9	hSpCas9	negative selection	11077938
218367	218390	5	-	28162770	P31FUJ	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.40042126512459286	[546]	[486]	-4	hSpCas9	negative selection	11077939
235292	235315	5	+	28162770	P31FUJ	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.3031915323057763	[293]	[34]	-9	hSpCas9	negative selection	11077940
230990	231013	5	-	28162770	OCIAML5	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.571257463302227	[120]	[146]	-4	hSpCas9	negative selection	11247297
251435	251458	5	+	28162770	OCIAML5	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-2.9143508491183394	[70]	[16]	-8	hSpCas9	negative selection	11247298
233565	233588	5	+	28162770	OCIAML5	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.14793342913600305	[31]	[63]	1	hSpCas9	negative selection	11247299
236498	236521	5	-	28162770	OCIAML5	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-1.7525308973130824	[55]	[29]	-7	hSpCas9	negative selection	11247300
225514	225537	5	+	28162770	OCIAML5	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.4447647203647587	[186]	[61]	-8	hSpCas9	negative selection	11247301
225549	225572	5	-	28162770	OCIAML5	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-5.327800001830394	[88]	[3]	-9	hSpCas9	negative selection	11247302
230910	230933	5	+	28162770	OCIAML5	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-4.370795373185066	[148]	[12]	-9	hSpCas9	negative selection	11247303
235314	235337	5	+	28162770	OCIAML5	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-3.0645161889528665	[240]	[51]	-8	hSpCas9	negative selection	11247304
218367	218390	5	-	28162770	OCIAML5	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.23853491794606974	[199]	[305]	-2	hSpCas9	negative selection	11247305
235292	235315	5	+	28162770	OCIAML5	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-8.538567098047215	[205]	[0]	-9	hSpCas9	negative selection	11247306
230990	231013	5	-	28162770	EOL1	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.2099024282018464	[471]	[214]	-2	hSpCas9	negative selection	11416663
251435	251458	5	+	28162770	EOL1	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-2.3407967949504602	[124]	[12]	-8	hSpCas9	negative selection	11416664
233565	233588	5	+	28162770	EOL1	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-1.1384620259552658	[116]	[27]	-6	hSpCas9	negative selection	11416665
236498	236521	5	-	28162770	EOL1	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-7.323379741873051	[303]	[0]	-9	hSpCas9	negative selection	11416666
225514	225537	5	+	28162770	EOL1	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.2647225795912047	[487]	[106]	-7	hSpCas9	negative selection	11416667
225549	225572	5	-	28162770	EOL1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-3.5065020456969407	[150]	[6]	-9	hSpCas9	negative selection	11416668
230910	230933	5	+	28162770	EOL1	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-4.0829467649763895	[192]	[5]	-9	hSpCas9	negative selection	11416669
235314	235337	5	+	28162770	EOL1	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.564387841376846	[246]	[21]	-8	hSpCas9	negative selection	11416670
218367	218390	5	-	28162770	EOL1	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.10814084713563987	[490]	[239]	-1	hSpCas9	negative selection	11416671
235292	235315	5	+	28162770	EOL1	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-0.9879893871791259	[255]	[67]	-6	hSpCas9	negative selection	11416672
230990	231013	5	-	28162770	MOLM13	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.24548939230401146	[363]	[221]	-1	hSpCas9	negative selection	11586029
251435	251458	5	+	28162770	MOLM13	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.7715765531508105	[169]	[35]	-7	hSpCas9	negative selection	11586030
233565	233588	5	+	28162770	MOLM13	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	1.7191727816860152	[112]	[268]	9	hSpCas9	negative selection	11586031
236498	236521	5	-	28162770	MOLM13	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-7.039905258654118	[181]	[0]	-9	hSpCas9	negative selection	11586032
225514	225537	5	+	28162770	MOLM13	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-0.7310916531818167	[488]	[212]	-4	hSpCas9	negative selection	11586033
225549	225572	5	-	28162770	MOLM13	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-3.6818577379601036	[141]	[7]	-9	hSpCas9	negative selection	11586034
230910	230933	5	+	28162770	MOLM13	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-7.339465540513026	[223]	[0]	-9	hSpCas9	negative selection	11586035
235314	235337	5	+	28162770	MOLM13	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-4.651051691178928	[555]	[15]	-9	hSpCas9	negative selection	11586036
218367	218390	5	-	28162770	MOLM13	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.4280022151146827	[587]	[315]	-3	hSpCas9	negative selection	11586037
235292	235315	5	+	28162770	MOLM13	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-2.945413066363517	[276]	[25]	-8	hSpCas9	negative selection	11586038
230990	231013	5	-	28162770	HEL	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	0.20278876275602553	[330]	[243]	1	hSpCas9	negative selection	11755395
251435	251458	5	+	28162770	HEL	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-3.1298506718965706	[122]	[8]	-9	hSpCas9	negative selection	11755396
233565	233588	5	+	28162770	HEL	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.17926286602164887	[98]	[55]	-1	hSpCas9	negative selection	11755397
236498	236521	5	-	28162770	HEL	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-2.4039544034476847	[156]	[18]	-8	hSpCas9	negative selection	11755398
225514	225537	5	+	28162770	HEL	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-3.723583382245459	[329]	[15]	-9	hSpCas9	negative selection	11755399
225549	225572	5	-	28162770	HEL	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-4.760983354050653	[126]	[2]	-9	hSpCas9	negative selection	11755400
230910	230933	5	+	28162770	HEL	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-2.3191931271661237	[186]	[23]	-8	hSpCas9	negative selection	11755401
235314	235337	5	+	28162770	HEL	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-4.138620881524303	[439]	[15]	-9	hSpCas9	negative selection	11755402
218367	218390	5	-	28162770	HEL	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.190253649939625	[439]	[246]	-1	hSpCas9	negative selection	11755403
235292	235315	5	+	28162770	HEL	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-2.738082951940574	[249]	[23]	-8	hSpCas9	negative selection	11755404
230990	231013	5	-	28162770	MV411	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	0.40663614563202916	[239]	[267]	3	hSpCas9	negative selection	11924761
251435	251458	5	+	28162770	MV411	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-1.512611656496472	[104]	[30]	-7	hSpCas9	negative selection	11924762
233565	233588	5	+	28162770	MV411	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	-0.243548801729367	[51]	[36]	-2	hSpCas9	negative selection	11924763
236498	236521	5	-	28162770	MV411	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-4.530170027880777	[191]	[6]	-9	hSpCas9	negative selection	11924764
225514	225537	5	+	28162770	MV411	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.9473193036394725	[292]	[31]	-9	hSpCas9	negative selection	11924765
225549	225572	5	-	28162770	MV411	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-6.2761244052742375	[91]	[0]	-9	hSpCas9	negative selection	11924766
230910	230933	5	+	28162770	MV411	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-4.286541021219576	[138]	[5]	-9	hSpCas9	negative selection	11924767
235314	235337	5	+	28162770	MV411	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-1.9916336117003028	[202]	[42]	-8	hSpCas9	negative selection	11924768
218367	218390	5	-	28162770	MV411	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.12969195991988125	[312]	[240]	-1	hSpCas9	negative selection	11924769
235292	235315	5	+	28162770	MV411	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-0.8625352912423562	[217]	[100]	-5	hSpCas9	negative selection	11924770
230990	231013	5	-	28162770	MONOMAC1	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-1.1886246072433535	[170]	[85]	-7	hSpCas9	negative selection	12094127
251435	251458	5	+	28162770	MONOMAC1	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-2.0621072669734453	[50]	[13]	-9	hSpCas9	negative selection	12094128
233565	233588	5	+	28162770	MONOMAC1	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	1.4493261983257457	[45]	[143]	9	hSpCas9	negative selection	12094129
236498	236521	5	-	28162770	MONOMAC1	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-2.8159466797040476	[85]	[13]	-9	hSpCas9	negative selection	12094130
225514	225537	5	+	28162770	MONOMAC1	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.1970368470595536	[175]	[87]	-7	hSpCas9	negative selection	12094131
225549	225572	5	-	28162770	MONOMAC1	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-0.23656521124619134	[36]	[35]	-2	hSpCas9	negative selection	12094132
230910	230933	5	+	28162770	MONOMAC1	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.2543700221255052	[76]	[36]	-7	hSpCas9	negative selection	12094133
235314	235337	5	+	28162770	MONOMAC1	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-1.886696726447403	[99]	[30]	-8	hSpCas9	negative selection	12094134
218367	218390	5	-	28162770	MONOMAC1	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.37212355361764515	[244]	[216]	-3	hSpCas9	negative selection	12094135
235292	235315	5	+	28162770	MONOMAC1	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-1.9603365890392224	[128]	[37]	-8	hSpCas9	negative selection	12094136
230990	231013	5	-	28162770	OCIAML2	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.03418984923109303	[45]	[248]	0	hSpCas9	negative selection	12263493
251435	251458	5	+	28162770	OCIAML2	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-3.307131092959282	[24]	[13]	-9	hSpCas9	negative selection	12263494
233565	233588	5	+	28162770	OCIAML2	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.21968567562522356	[21]	[141]	2	hSpCas9	negative selection	12263495
236498	236521	5	-	28162770	OCIAML2	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-5.930061443879459	[32]	[2]	-9	hSpCas9	negative selection	12263496
225514	225537	5	+	28162770	OCIAML2	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-2.2482374039057134	[65]	[76]	-8	hSpCas9	negative selection	12263497
225549	225572	5	-	28162770	OCIAML2	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-4.52952351429573	[24]	[5]	-9	hSpCas9	negative selection	12263498
230910	230933	5	+	28162770	OCIAML2	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-2.9300614438794588	[21]	[15]	-9	hSpCas9	negative selection	12263499
235314	235337	5	+	28162770	OCIAML2	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-4.248237403905714	[47]	[13]	-9	hSpCas9	negative selection	12263500
218367	218390	5	-	28162770	OCIAML2	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	-0.9112024166281425	[75]	[223]	-6	hSpCas9	negative selection	12263501
235292	235315	5	+	28162770	OCIAML2	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-2.855293675477486	[46]	[35]	-9	hSpCas9	negative selection	12263502
230990	231013	5	-	28162770	OCIAML3	viability	GTCCTGCCCTACCTGTAGGGTGG	SDHA	ENSG00000073578	-0.7626072442999081	[67]	[120]	-5	hSpCas9	negative selection	12432859
251435	251458	5	+	28162770	OCIAML3	viability	GTCACGGGGCGCGCATGCCAGGG	SDHA	ENSG00000073578	-0.7360266451965911	[31]	[57]	-5	hSpCas9	negative selection	12432860
233565	233588	5	+	28162770	OCIAML3	viability	GCGATACGCCCCTGTCGCGAAGG	SDHA	ENSG00000073578	0.4059923596758367	[20]	[83]	4	hSpCas9	negative selection	12432861
236498	236521	5	-	28162770	OCIAML3	viability	GCGGTTGGCACCATGTACCGAGG	SDHA	ENSG00000073578	-3.387556762856737	[51]	[14]	-9	hSpCas9	negative selection	12432862
225514	225537	5	+	28162770	OCIAML3	viability	GGATGCCATCCACTACATGACGG	SDHA	ENSG00000073578	-1.970861945715119	[86]	[66]	-8	hSpCas9	negative selection	12432863
225549	225572	5	-	28162770	OCIAML3	viability	GCCCATCACCTCGACCACGGCGG	SDHA	ENSG00000073578	-2.313899721131428	[27]	[16]	-9	hSpCas9	negative selection	12432864
230910	230933	5	+	28162770	OCIAML3	viability	GCCCACACCAGCACTGGCGACGG	SDHA	ENSG00000073578	-1.996106083895509	[36]	[27]	-8	hSpCas9	negative selection	12432865
235314	235337	5	+	28162770	OCIAML3	viability	GCATTCCCACCAACTACAAGGGG	SDHA	ENSG00000073578	-2.231437560939455	[55]	[35]	-8	hSpCas9	negative selection	12432866
218367	218390	5	-	28162770	OCIAML3	viability	TCAGCAGCCGCGACAGGCCCCGG	SDHA	ENSG00000073578	0.8546775968491379	[97]	[534]	7	hSpCas9	negative selection	12432867
235292	235315	5	+	28162770	OCIAML3	viability	ACCGTGCATTATAACATGGGCGG	SDHA	ENSG00000073578	-3.64131335510252	[61]	[14]	-9	hSpCas9	negative selection	12432868