Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8148
• Symbol: TAF15
• Description: TATA-box binding protein associated factor 15

DataSource: http://genomecrispr.dkfz.de/#!/results/TAF15

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
35844100	35844123	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000276833	-0.04102898170816982	[175]	[128]	0	hSpCas9	negative selection	160352
35844100	35844123	17	+	26472758	Jiyoye	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.04102898170816982	[175]	[128]	0	hSpCas9	negative selection	160353
35844710	35844733	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000276833	-3.177787119215283	[11]	[0]	-9	hSpCas9	negative selection	160354
35844710	35844733	17	+	26472758	Jiyoye	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.177787119215283	[11]	[0]	-9	hSpCas9	negative selection	160355
35844581	35844604	17	+	26472758	Jiyoye	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-2.4508056136216987	[86]	[11]	-8	hSpCas9	negative selection	160356
35844581	35844604	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000276833	-2.4508056136216987	[86]	[11]	-8	hSpCas9	negative selection	160357
35844082	35844105	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000276833	-0.5752305584793885	[325]	[164]	-4	hSpCas9	negative selection	160358
35844082	35844105	17	+	26472758	Jiyoye	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.5752305584793885	[325]	[164]	-4	hSpCas9	negative selection	160359
35844344	35844367	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000276833	0.3485211637850629	[250]	[240]	2	hSpCas9	negative selection	160360
35844344	35844367	17	+	26472758	Jiyoye	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	0.3485211637850629	[250]	[240]	2	hSpCas9	negative selection	160361
35844356	35844379	17	-	26472758	Jiyoye	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.840752131937712	[189]	[79]	-5	hSpCas9	negative selection	160362
35844356	35844379	CHR_HSCHR17_7_CTG4	-	26472758	Jiyoye	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000276833	-0.840752131937712	[189]	[79]	-5	hSpCas9	negative selection	160363
35844503	35844526	17	+	26472758	Jiyoye	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	-0.8882805020202978	[161]	[65]	-6	hSpCas9	negative selection	160364
35844503	35844526	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000276833	-0.8882805020202978	[161]	[65]	-6	hSpCas9	negative selection	160365
35844527	35844550	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000276833	-2.914752713381489	[39]	[3]	-9	hSpCas9	negative selection	160366
35844527	35844550	17	+	26472758	Jiyoye	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-2.914752713381489	[39]	[3]	-9	hSpCas9	negative selection	160367
35844662	35844685	17	+	26472758	Jiyoye	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.08381097100626886	[103]	[73]	0	hSpCas9	negative selection	160368
35844662	35844685	CHR_HSCHR17_7_CTG4	+	26472758	Jiyoye	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000276833	-0.08381097100626886	[103]	[73]	0	hSpCas9	negative selection	160369
35844100	35844123	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000276833	0.06490551360716623	[733,499]	[250,341]	0	hSpCas9	negative selection	351470
35844100	35844123	17	+	26472758	KBM7	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	0.06490551360716623	[733,499]	[250,341]	0	hSpCas9	negative selection	351471
35844710	35844733	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000276833	-3.27312012880061	[57,26]	[1,1]	-9	hSpCas9	negative selection	351472
35844710	35844733	17	+	26472758	KBM7	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.27312012880061	[57,26]	[1,1]	-9	hSpCas9	negative selection	351473
35844581	35844604	17	+	26472758	KBM7	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.057964725117055194	[219,152]	[118,50]	0	hSpCas9	negative selection	351474
35844581	35844604	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000276833	-0.057964725117055194	[219,152]	[118,50]	0	hSpCas9	negative selection	351475
35844082	35844105	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000276833	-0.2755292809480885	[1128,689]	[321,367]	-3	hSpCas9	negative selection	351476
35844082	35844105	17	+	26472758	KBM7	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.2755292809480885	[1128,689]	[321,367]	-3	hSpCas9	negative selection	351477
35844344	35844367	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000276833	0.041630406244515195	[1053,911]	[643,322]	0	hSpCas9	negative selection	351478
35844344	35844367	17	+	26472758	KBM7	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	0.041630406244515195	[1053,911]	[643,322]	0	hSpCas9	negative selection	351479
35844356	35844379	17	-	26472758	KBM7	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.6071109349144244	[1078,716]	[360,193]	-5	hSpCas9	negative selection	351480
35844356	35844379	CHR_HSCHR17_7_CTG4	-	26472758	KBM7	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000276833	-0.6071109349144244	[1078,716]	[360,193]	-5	hSpCas9	negative selection	351481
35844503	35844526	17	+	26472758	KBM7	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.12239327099886967	[469,470]	[222,258]	1	hSpCas9	negative selection	351482
35844503	35844526	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000276833	0.12239327099886967	[469,470]	[222,258]	1	hSpCas9	negative selection	351483
35844527	35844550	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000276833	-6.711941298402308	[233,211]	[0,0]	-9	hSpCas9	negative selection	351484
35844527	35844550	17	+	26472758	KBM7	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-6.711941298402308	[233,211]	[0,0]	-9	hSpCas9	negative selection	351485
35844662	35844685	17	+	26472758	KBM7	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.6829220635918759	[739,775]	[192,250]	-5	hSpCas9	negative selection	351486
35844662	35844685	CHR_HSCHR17_7_CTG4	+	26472758	KBM7	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000276833	-0.6829220635918759	[739,775]	[192,250]	-5	hSpCas9	negative selection	351487
35844100	35844123	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000276833	-1.5609949735351942	[355]	[27]	-8	hSpCas9	negative selection	542588
35844100	35844123	17	+	26472758	Raji	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-1.5609949735351942	[355]	[27]	-8	hSpCas9	negative selection	542589
35844710	35844733	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000276833	-2.214544559513763	[19]	[0]	-8	hSpCas9	negative selection	542590
35844710	35844733	17	+	26472758	Raji	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-2.214544559513763	[19]	[0]	-8	hSpCas9	negative selection	542591
35844581	35844604	17	+	26472758	Raji	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.1196853731723215	[102]	[10]	-7	hSpCas9	negative selection	542592
35844581	35844604	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000276833	-1.1196853731723215	[102]	[10]	-7	hSpCas9	negative selection	542593
35844082	35844105	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000276833	0.6259256104063033	[362]	[129]	6	hSpCas9	negative selection	542594
35844082	35844105	17	+	26472758	Raji	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.6259256104063033	[362]	[129]	6	hSpCas9	negative selection	542595
35844344	35844367	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000276833	-0.3668755009413368	[488]	[87]	-3	hSpCas9	negative selection	542596
35844344	35844367	17	+	26472758	Raji	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.3668755009413368	[488]	[87]	-3	hSpCas9	negative selection	542597
35844356	35844379	17	-	26472758	Raji	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.6802081318625746	[434]	[62]	-5	hSpCas9	negative selection	542598
35844356	35844379	CHR_HSCHR17_7_CTG4	-	26472758	Raji	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000276833	-0.6802081318625746	[434]	[62]	-5	hSpCas9	negative selection	542599
35844503	35844526	17	+	26472758	Raji	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	-0.2618502742921196	[278]	[53]	-2	hSpCas9	negative selection	542600
35844503	35844526	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000276833	-0.2618502742921196	[278]	[53]	-2	hSpCas9	negative selection	542601
35844527	35844550	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000276833	-3.436936980850211	[139]	[2]	-9	hSpCas9	negative selection	542602
35844527	35844550	17	+	26472758	Raji	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-3.436936980850211	[139]	[2]	-9	hSpCas9	negative selection	542603
35844662	35844685	17	+	26472758	Raji	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-1.3844695609560753	[539]	[47]	-7	hSpCas9	negative selection	542604
35844662	35844685	CHR_HSCHR17_7_CTG4	+	26472758	Raji	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000276833	-1.3844695609560753	[539]	[47]	-7	hSpCas9	negative selection	542605
35844100	35844123	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000276833	-0.2641928869245946	[551]	[387]	-2	hSpCas9	negative selection	733706
35844100	35844123	17	+	26472758	K562	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.2641928869245946	[551]	[387]	-2	hSpCas9	negative selection	733707
35844710	35844733	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000276833	-5.588471286498294	[56]	[0]	-9	hSpCas9	negative selection	733708
35844710	35844733	17	+	26472758	K562	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-5.588471286498294	[56]	[0]	-9	hSpCas9	negative selection	733709
35844581	35844604	17	+	26472758	K562	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-3.6325703822282094	[190]	[12]	-9	hSpCas9	negative selection	733710
35844581	35844604	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000276833	-3.6325703822282094	[190]	[12]	-9	hSpCas9	negative selection	733711
35844082	35844105	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000276833	1.1570128817757548	[790]	[1488]	8	hSpCas9	negative selection	733712
35844082	35844105	17	+	26472758	K562	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	1.1570128817757548	[790]	[1488]	8	hSpCas9	negative selection	733713
35844344	35844367	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000276833	0.03796785019902038	[869]	[753]	0	hSpCas9	negative selection	733714
35844344	35844367	17	+	26472758	K562	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	0.03796785019902038	[869]	[753]	0	hSpCas9	negative selection	733715
35844356	35844379	17	-	26472758	K562	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.5013304250829984	[658]	[392]	-3	hSpCas9	negative selection	733716
35844356	35844379	CHR_HSCHR17_7_CTG4	-	26472758	K562	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000276833	-0.5013304250829984	[658]	[392]	-3	hSpCas9	negative selection	733717
35844503	35844526	17	+	26472758	K562	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.820656480167519	[386]	[576]	6	hSpCas9	negative selection	733718
35844503	35844526	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000276833	0.820656480167519	[386]	[576]	6	hSpCas9	negative selection	733719
35844527	35844550	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000276833	-3.916573149005858	[160]	[8]	-9	hSpCas9	negative selection	733720
35844527	35844550	17	+	26472758	K562	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-3.916573149005858	[160]	[8]	-9	hSpCas9	negative selection	733721
35844662	35844685	17	+	26472758	K562	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-2.1428853760729396	[789]	[150]	-7	hSpCas9	negative selection	733722
35844662	35844685	CHR_HSCHR17_7_CTG4	+	26472758	K562	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000276833	-2.1428853760729396	[789]	[150]	-7	hSpCas9	negative selection	733723
35842417	35842440	17	+	26627737	DLD1	viability	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.6077884271449057	[267]	[116,71,182]	6	hSpCas9	negative selection	797123
35844097	35844120	17	+	26627737	DLD1	viability	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.18330404047304083	[772]	[210,269,166]	-2	hSpCas9	negative selection	797124
35844487	35844510	17	+	26627737	DLD1	viability	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.4516267076874554	[86]	[53,14,40]	4	hSpCas9	negative selection	797125
35842417	35842440	17	+	26627737	GBM cells	viability after 5 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.26250460874585335	[156]	[94,106]	4	hSpCas9	negative selection	879438
35844097	35844120	17	+	26627737	GBM cells	viability after 5 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.047436399595773615	[497]	[314,236]	0	hSpCas9	negative selection	879439
35844487	35844510	17	+	26627737	GBM cells	viability after 5 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.23233065839256717	[160]	[54,91]	-4	hSpCas9	negative selection	879440
35842417	35842440	17	+	26627737	GBM cells	viability after 13 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.7865051007320714	[156]	[152,141]	8	hSpCas9	negative selection	961753
35844097	35844120	17	+	26627737	GBM cells	viability after 13 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.29230210207850327	[497]	[202,234]	-3	hSpCas9	negative selection	961754
35844487	35844510	17	+	26627737	GBM cells	viability after 13 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.4357785073696233	[160]	[52,73]	-5	hSpCas9	negative selection	961755
35842417	35842440	17	+	26627737	GBM cells	viability after 21 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.7256185816771363	[156]	[139,141]	7	hSpCas9	negative selection	1044068
35844097	35844120	17	+	26627737	GBM cells	viability after 21 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.6031869484030263	[497]	[422,399]	6	hSpCas9	negative selection	1044069
35844487	35844510	17	+	26627737	GBM cells	viability after 21 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.04961445119804209	[160]	[95,73]	0	hSpCas9	negative selection	1044070
35842417	35842440	17	+	26627737	RPE1	viability after 9 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.03738496236813493	[407]	[137,106]	0	hSpCas9	negative selection	1126383
35844097	35844120	17	+	26627737	RPE1	viability after 9 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-1.905714188787241	[2022]	[151,190]	-8	hSpCas9	negative selection	1126384
35844487	35844510	17	+	26627737	RPE1	viability after 9 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-2.8435079412225837	[567]	[5,48]	-9	hSpCas9	negative selection	1126385
35842417	35842440	17	+	26627737	RPE1	viability after 12 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.3649903932041869	[407]	[163,116]	2	hSpCas9	negative selection	1208698
35844097	35844120	17	+	26627737	RPE1	viability after 12 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-2.3358689602173284	[2022]	[44,173]	-9	hSpCas9	negative selection	1208699
35844487	35844510	17	+	26627737	RPE1	viability after 12 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-2.3222227930889567	[567]	[47,11]	-9	hSpCas9	negative selection	1208700
35842417	35842440	17	+	26627737	RPE1	viability after 15 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.5049835555337134	[407]	[203,124]	3	hSpCas9	negative selection	1291013
35844097	35844120	17	+	26627737	RPE1	viability after 15 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-2.972944533132066	[2022]	[22,120]	-9	hSpCas9	negative selection	1291014
35844487	35844510	17	+	26627737	RPE1	viability after 15 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-2.178618949456222	[567]	[35,34]	-8	hSpCas9	negative selection	1291015
35842417	35842440	17	+	26627737	RPE1	viability after 18 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.013444031712163018	[407]	[85,137]	0	hSpCas9	negative selection	1373328
35844097	35844120	17	+	26627737	RPE1	viability after 18 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-2.4721927099194825	[2022]	[65,132]	-8	hSpCas9	negative selection	1373329
35844487	35844510	17	+	26627737	RPE1	viability after 18 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-1.5740430859137908	[567]	[50,51]	-7	hSpCas9	negative selection	1373330
35842417	35842440	17	+	26627737	HeLa	viability after 8 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.9365568087434311	[125]	[75,120,110]	7	hSpCas9	negative selection	1455643
35844097	35844120	17	+	26627737	HeLa	viability after 8 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.2221294919577137	[1212]	[872,508,527]	2	hSpCas9	negative selection	1455644
35844487	35844510	17	+	26627737	HeLa	viability after 8 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.7281029310212253	[329]	[116,66,82]	-6	hSpCas9	negative selection	1455645
35842417	35842440	17	+	26627737	HeLa	viability after 12 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	1.5202337040248233	[125]	[198,125,126]	8	hSpCas9	negative selection	1537958
35844097	35844120	17	+	26627737	HeLa	viability after 12 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.1190924859407354	[1212]	[656,275,731]	1	hSpCas9	negative selection	1537959
35844487	35844510	17	+	26627737	HeLa	viability after 12 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.4342746769703013	[329]	[116,74,113]	-4	hSpCas9	negative selection	1537960
35842417	35842440	17	+	26627737	HeLa	viability after 15 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.18890617621466554	[125]	[27,86,60]	1	hSpCas9	negative selection	1620273
35844097	35844120	17	+	26627737	HeLa	viability after 15 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.3136419095856713	[1212]	[422,342,427]	-3	hSpCas9	negative selection	1620274
35844487	35844510	17	+	26627737	HeLa	viability after 15 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.7268210772049337	[329]	[67,114,58]	-6	hSpCas9	negative selection	1620275
35842417	35842440	17	+	26627737	HeLa	viability after 18 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.3265111538045442	[125]	[22,80,60]	2	hSpCas9	negative selection	1702588
35844097	35844120	17	+	26627737	HeLa	viability after 18 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.3362738723341223	[1212]	[270,284,427]	-3	hSpCas9	negative selection	1702589
35844487	35844510	17	+	26627737	HeLa	viability after 18 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.6730523485348283	[329]	[46,100,58]	-5	hSpCas9	negative selection	1702590
35842417	35842440	17	+	26627737	HCT116	viability after 6 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-3.9967513714154093	[166]	[0,1]	-9	hSpCas9	negative selection	1784903
35844097	35844120	17	+	26627737	HCT116	viability after 6 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	1.270401551473429	[1038]	[413,382]	6	hSpCas9	negative selection	1784904
35844487	35844510	17	+	26627737	HCT116	viability after 6 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	1.1774376847191614	[251]	[77,95]	6	hSpCas9	negative selection	1784905
35842417	35842440	17	+	26627737	HCT116	viability after 8 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.18897896454575625	[208]	[104,84,112]	-2	hSpCas9	negative selection	1867218
35844097	35844120	17	+	26627737	HCT116	viability after 8 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.4467070237626405	[680]	[409,734,388]	4	hSpCas9	negative selection	1867219
35844487	35844510	17	+	26627737	HCT116	viability after 8 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.34571943021730905	[284]	[96,127,144]	-4	hSpCas9	negative selection	1867220
35842417	35842440	17	+	26627737	HCT116	viability after 9 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.0966455001787987	[166]	[34,46]	0	hSpCas9	negative selection	1949533
35844097	35844120	17	+	26627737	HCT116	viability after 9 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.1449644853806945	[1038]	[308,204]	-1	hSpCas9	negative selection	1949534
35844487	35844510	17	+	26627737	HCT116	viability after 9 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.307907668739388	[251]	[89,77]	2	hSpCas9	negative selection	1949535
35842417	35842440	17	+	26627737	HCT116	viability after 12 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.1374509933871949	[208]	[97,69,130]	-1	hSpCas9	negative selection	2031848
35844097	35844120	17	+	26627737	HCT116	viability after 12 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.04303908914273746	[680]	[388,352,361]	0	hSpCas9	negative selection	2031849
35844487	35844510	17	+	26627737	HCT116	viability after 12 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.4510419078185309	[284]	[127,147,51]	-5	hSpCas9	negative selection	2031850
35842417	35842440	17	+	26627737	HCT116	viability after 15 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.3908340014424727	[208]	[178,74,31]	-4	hSpCas9	negative selection	2114163
35844097	35844120	17	+	26627737	HCT116	viability after 15 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.03959966098933099	[680]	[347,418,431]	0	hSpCas9	negative selection	2114164
35844487	35844510	17	+	26627737	HCT116	viability after 15 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.02814193820858049	[284]	[131,262,83]	0	hSpCas9	negative selection	2114165
35842417	35842440	17	+	26627737	HCT116	viability after 18 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.8961049833081483	[208]	[48,63,48]	-7	hSpCas9	negative selection	2196478
35844097	35844120	17	+	26627737	HCT116	viability after 18 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.09879742542322068	[680]	[186,410,317]	-1	hSpCas9	negative selection	2196479
35844487	35844510	17	+	26627737	HCT116	viability after 18 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.139166704795641	[284]	[109,281,49]	1	hSpCas9	negative selection	2196480
35809555	35809578	17	+	24336569	HL60	viability	CCGCGGCCGTTAGTCATGTCGGG	TAF15	ENSG00000270647	2.014236315791689	[112]	[965]	9	hSpCas9	negative selection	2298809
35809555	35809578	17	+	24336569	KBM7	viability	CCGCGGCCGTTAGTCATGTCGGG	TAF15	ENSG00000270647	0.5780693908217277	[222]	[907]	5	hSpCas9	negative selection	2365986
35802449	35802472	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCACTGCACTCCAGCCTGGAGG	TAF15	ENSG00000270647	1.049956001898007	[3,11]	[2,3]	4	dCas9-VP64	positive selection	2389123
35839405	35839428	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTTTGTCTCCCGGG	TAF15	ENSG00000270647	-0.7059861923714007	[63,29]	[9,1]	-4	dCas9-VP64	positive selection	2425239
35839405	35839428	CHR_HSCHR17_7_CTG4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTTTGTCTCCCGGG	TAF15	ENSG00000276833	-0.7059861923714007	[63,29]	[9,1]	-4	dCas9-VP64	positive selection	2425240
35809313	35809336	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATGGTACGGCTAGCGGAGGGGG	TAF15	ENSG00000270647	-2.0993176039409644	[76,102]	[3,3]	-9	dCas9-VP64	positive selection	2433052
35809263	35809286	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCAATGCCACGATCACGATCGG	TAF15	ENSG00000270647	2.3249674467727957	[187,336]	[494,72]	7	dCas9-VP64	positive selection	2433053
35809357	35809380	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTACTAGCCGCCGAGCCCTGAGG	TAF15	ENSG00000270647	-0.9745837485156943	[1,28]	[1,0]	-6	dCas9-VP64	positive selection	2433054
35795794	35795817	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGGTCAACTGGAGGTGGCGGG	TAF15	ENSG00000270647	-0.0035612927599339983	[59,9]	[8,4]	0	dCas9-VP64	positive selection	2460332
35795870	35795893	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCTCTTCATCGAAGTCTTAGG	TAF15	ENSG00000270647	-0.34175268798416725	[68,423]	[4,83]	-1	dCas9-VP64	positive selection	2460333
35795847	35795870	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAGCCACGCTTGCCAGGAGAAGG	TAF15	ENSG00000270647	-0.9974658850339855	[50,32]	[3,3]	-6	dCas9-VP64	positive selection	2460334
35731472	35731495	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AACTTGGAGGAGCTGAAGAAAGG	TAF15	ENSG00000270647	2.705795644281439	[66,2]	[93,2]	8	dCas9-VP64	positive selection	2461283
35731543	35731566	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGACGAATTCTTTAATCCCTGG	TAF15	ENSG00000270647	0.16140117572945462	[180,24]	[41,5]	0	dCas9-VP64	positive selection	2461284
35731504	35731527	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCCCGCAGGGAGAGTCTGGAGG	TAF15	ENSG00000270647	-1.0076435405883595	[281,114]	[35,4]	-6	dCas9-VP64	positive selection	2461285
35753040	35753063	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGACTGAGGAATGTGGGGGGG	TAF15	ENSG00000270647	-0.4079458791816166	[34,8]	[2,2]	-2	dCas9-VP64	positive selection	2464983
35752959	35752982	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGTGTACTCGCTGAGAGCCCGG	TAF15	ENSG00000270647	2.027951032698751	[58,70]	[89,24]	7	dCas9-VP64	positive selection	2464984
35752977	35753000	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTAGCAGCACTGGAGGTCCCGGG	TAF15	ENSG00000270647	0.4669931497212662	[186,25]	[52,8]	2	dCas9-VP64	positive selection	2464985
35831289	35831312	CHR_HSCHR17_7_CTG4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGAGG	TAF15	ENSG00000276833	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465877
35831289	35831312	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGAGG	TAF15	ENSG00000270647	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465878
35802449	35802472	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCACTGCACTCCAGCCTGGAGG	TAF15	ENSG00000270647	0.3100958641524221	[17,26]	[5,11]	2	dCas9-VP64	positive selection	2484378
35839405	35839428	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTTTGTCTCCCGGG	TAF15	ENSG00000270647	1.0992483033047402	[46,34]	[13,41]	7	dCas9-VP64	positive selection	2520494
35839405	35839428	CHR_HSCHR17_7_CTG4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTTTGTCTCCCGGG	TAF15	ENSG00000276833	1.0992483033047402	[46,34]	[13,41]	7	dCas9-VP64	positive selection	2520495
35809313	35809336	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATGGTACGGCTAGCGGAGGGGG	TAF15	ENSG00000270647	0.38357357861819075	[69,50]	[29,20]	3	dCas9-VP64	positive selection	2528307
35809263	35809286	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCAATGCCACGATCACGATCGG	TAF15	ENSG00000270647	0.43463839932147774	[449,442]	[160,229]	3	dCas9-VP64	positive selection	2528308
35809357	35809380	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTACTAGCCGCCGAGCCCTGAGG	TAF15	ENSG00000270647	-0.9164727368495915	[93,68]	[13,13]	-8	dCas9-VP64	positive selection	2528309
35795794	35795817	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGGTCAACTGGAGGTGGCGGG	TAF15	ENSG00000270647	-0.37560054154901534	[86,9]	[15,8]	-4	dCas9-VP64	positive selection	2555587
35795870	35795893	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCTCTTCATCGAAGTCTTAGG	TAF15	ENSG00000270647	-0.21516658739990419	[256,109]	[56,45]	-2	dCas9-VP64	positive selection	2555588
35795847	35795870	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAGCCACGCTTGCCAGGAGAAGG	TAF15	ENSG00000270647	0.33139752329454936	[124,198]	[29,99]	2	dCas9-VP64	positive selection	2555589
35731472	35731495	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AACTTGGAGGAGCTGAAGAAAGG	TAF15	ENSG00000270647	1.3353217575675296	[57,91]	[88,34]	7	dCas9-VP64	positive selection	2556538
35731543	35731566	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGACGAATTCTTTAATCCCTGG	TAF15	ENSG00000270647	-0.18037234661990142	[41,61]	[13,14]	-2	dCas9-VP64	positive selection	2556539
35731504	35731527	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCCCGCAGGGAGAGTCTGGAGG	TAF15	ENSG00000270647	-0.0734782423391263	[135,88]	[33,34]	0	dCas9-VP64	positive selection	2556540
35753040	35753063	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGACTGAGGAATGTGGGGGGG	TAF15	ENSG00000270647	2.950544332354613	[87,250]	[41,784]	9	dCas9-VP64	positive selection	2560238
35752959	35752982	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGTGTACTCGCTGAGAGCCCGG	TAF15	ENSG00000270647	-0.010236479059169301	[136,149]	[35,55]	0	dCas9-VP64	positive selection	2560239
35752977	35753000	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTAGCAGCACTGGAGGTCCCGGG	TAF15	ENSG00000270647	0.16432694703625797	[159,68]	[62,21]	1	dCas9-VP64	positive selection	2560240
35831289	35831312	CHR_HSCHR17_7_CTG4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGAGG	TAF15	ENSG00000276833	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561132
35831289	35831312	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGAGG	TAF15	ENSG00000270647	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561133
35838516	35838539	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	0.3119536401251561	[3,3]	[4,3]	6	hSpCas9	positive selection	3025177
35838516	35838539	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	0.510866461978454	[3,3]	[5,2]	8	hSpCas9	positive selection	3093035
35838484	35838507		-	24336571	A375	resistance to PLX after 7 days	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	-0.2662514918091587	[19,23]	[19,15]	-7	hSpCas9	positive selection	3148869
35838484	35838507		-	24336571	A375	resistance to PLX after 14 days	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	-0.7634607014201649	[17,17]	[4,3]	-8	hSpCas9	positive selection	3206662
35838484	35838507		-	24336571	A375	viability after 7 days	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7414110412276925	[13]	[19,23]	9	hSpCas9	negative selection	3264455
35838484	35838507		-	24336571	A375	viability after 14 days	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.4491443504852242	[13]	[17,17]	6	hSpCas9	negative selection	3322248
35838510	35838533	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.11777485904704155	[422,422]	[2,2]	0	hSpCas9	positive selection	3396063
35838484	35838507	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	-0.9324983474341821	[291,291]	[0,0]	-6	hSpCas9	positive selection	3396064
35838516	35838539	17	-	26780180	HT29	viability (Avana library 4 designs)	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	-1.0151369800736	[]	[]	-9	hSpCas9	negative selection	3463892
35838516	35838539	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	2.78121579535831	[]	[]	4	hSpCas9	negative selection	3566149
35838516	35838539	17	-	26780180	A375	viability (Avana lentiGuide)	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	-3.17511203110916	[]	[]	-5	hSpCas9	negative selection	3674808
35838516	35838539	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	0.1621916294539964	[5]	[5,5]	4	hSpCas9	positive selection	3783415
35838516	35838539	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCTGCCTTAGCTGAAGGAGGG	TAF15	ENSG00000270647	0.005718019446683164	[5]	[4,4]	0	hSpCas9	positive selection	3892022
35842377	35842400	17	-	26780180	A375	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.833944636700119	[]	[]	3	hSpCas9	negative selection	4001716
35842417	35842440	17	-	26780180	A375	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.484988421588681	[]	[]	1	hSpCas9	negative selection	4001717
35838484	35838507	17	-	26780180	A375	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.0126128115325465	[]	[]	0	hSpCas9	negative selection	4001718
35838510	35838533	17	+	26780180	A375	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	1.00551862228326	[]	[]	4	hSpCas9	negative selection	4001719
35842377	35842400	17	-	26780180	HT29	viability (GeCKOv2 library)	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.613500486781271	[]	[]	2	hSpCas9	negative selection	4109682
35842417	35842440	17	-	26780180	HT29	viability (GeCKOv2 library)	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.236780668093805	[]	[]	0	hSpCas9	negative selection	4109683
35838484	35838507	17	-	26780180	HT29	viability (GeCKOv2 library)	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	-0.160837648673559	[]	[]	-4	hSpCas9	negative selection	4109684
35838510	35838533	17	+	26780180	HT29	viability (GeCKOv2 library)	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	1.22709300918828	[]	[]	6	hSpCas9	negative selection	4109685
35838484	35838507	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	-0.12531902180729687	[3]	[2,1]	-3	hSpCas9	positive selection	4175154
35838484	35838507	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.20477746874462532	[3]	[4,0,2,0]	1	hSpCas9	positive selection	4239176
35842417	35842440	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.214959416770434	[3]	[3,2]	4	hSpCas9	positive selection	4301833
35842377	35842400	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.017352548686270453	[3]	[3,2]	0	hSpCas9	positive selection	4301834
35838510	35838533	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.18384044533536964	[3]	[2,3]	3	hSpCas9	positive selection	4366087
35838484	35838507	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.24368563705756446	[3]	[3,2]	5	hSpCas9	positive selection	4366088
35838511	35838533	17	+	27760321	OCIAML3	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.20953552563217448	[570,507]	[474,502]	2	hSpCas9	negative selection	4445067
35838511	35838533	17	+	27760321	OCIAML2	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.3882295300420029	[570,507]	[275,407]	-4	hSpCas9	negative selection	4528530
35838511	35838533	17	+	27760321	MV411	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.4212056535817782	[570,507]	[479,469]	3	hSpCas9	negative selection	4611993
35838511	35838533	17	+	27760321	HL60	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.025350492596878604	[570,507]	[425,470]	0	hSpCas9	negative selection	4695456
35838511	35838533	17	+	27760321	HT1080	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-3.3077665945435393	[507,396]	[11,24]	-7	hSpCas9	negative selection	4778919
35838511	35838533	17	+	27760321	HT29	viability after 7 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.05377034235430628	[507,396]	[810,538,493]	0	hSpCas9	negative selection	4862382
35838511	35838533	17	+	27760321	HT29	viability after 25 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.5190040357810171	[507,396]	[864,748,583]	6	hSpCas9	negative selection	4945845
35838511	35838533	17	+	27760321	HT29	viability after 22 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.4596110498012422	[507,396]	[1013,551,582]	5	hSpCas9	negative selection	5029308
35838511	35838533	17	+	27760321	HT29	viability after 19 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.10115471758977096	[507,396]	[918,358,429]	0	hSpCas9	negative selection	5112771
35838511	35838533	17	+	27760321	HT29	viability after 16 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.24604595847222516	[507,396]	[827,628,364]	2	hSpCas9	negative selection	5196234
35838511	35838533	17	+	27760321	HT29	viability after 13 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.005411291856707079	[507,396]	[677,288,596]	0	hSpCas9	negative selection	5279697
35838511	35838533	17	+	27760321	HT29	viability after 10 days	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.06877431612234075	[507,396]	[702,588,487]	0	hSpCas9	negative selection	5363160
35838511	35838533	17	+	27760321	MOLM13	viability	GATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.5934210656174095	[570,507]	[571,361]	4	hSpCas9	negative selection	5446623
35753195	35753218	17	+	27661255	K562	viability	GGCTGCCTCCTACCCTCTGCTGG	TAF15	ENSG00000270647	0.2640394722524163	[807,875]	[853,765]	8	dCas9-KRAB	negative selection	5481557
35753203	35753226	17	-	27661255	K562	viability	GGCCGCAGCCAGCAGAGGGTAGG	TAF15	ENSG00000270647	-0.1047904010163507	[705,833]	[613,532]	-4	dCas9-KRAB	negative selection	5481559
35809559	35809582	17	+	27661255	K562	viability	GGCCGTTAGTCATGTCGGGTAGG	TAF15	ENSG00000270647	0.2171489080829332	[554,769]	[630,594]	7	dCas9-KRAB	negative selection	5515748
35809752	35809775	17	+	27661255	K562	viability	GGCTCCCCGGCTGCAAATCACGG	TAF15	ENSG00000270647	-0.15723070216236534	[585,674]	[524,386]	-5	dCas9-KRAB	negative selection	5515749
35809479	35809502	17	-	27661255	K562	viability	GGCGGCCGGAGCTGTACTGAGGG	TAF15	ENSG00000270647	-0.11678810860324701	[466,694]	[458,395]	-4	dCas9-KRAB	negative selection	5515750
35809716	35809739	17	-	27661255	K562	viability	GTGCCTCCAGTTCAACATGGCGG	TAF15	ENSG00000270647	0.020546343795737776	[938,931]	[864,666]	0	dCas9-KRAB	negative selection	5515751
35842417	35842440	17	-	27260156	BXPC3	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6227422806350382	[653]	[833,1106,1029,1281]	9	hSpCas9	negative selection	5574293
35842377	35842400	17	-	27260156	BXPC3	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.016908788035312927	[884]	[852,845,976,997]	0	hSpCas9	negative selection	5574294
35838510	35838533	17	+	27260156	BXPC3	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.42535714415114423	[761]	[1017,983,1134,1157]	8	hSpCas9	negative selection	5638547
35838484	35838507	17	-	27260156	BXPC3	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6246606542995055	[466]	[757,628,743,899]	9	hSpCas9	negative selection	5638548
35842417	35842440	17	-	27260156	A673	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.4661461009957715	[653]	[1275,899,923,1275]	9	hSpCas9	negative selection	5695544
35842377	35842400	17	-	27260156	A673	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.13773415343912465	[884]	[1121,1000,1146,1416]	3	hSpCas9	negative selection	5695545
35838510	35838533	17	+	27260156	A673	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.3112328550397315	[761]	[1160,1097,1199,1079]	7	hSpCas9	negative selection	5759798
35838484	35838507	17	-	27260156	A673	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5066410441775834	[466]	[878,725,625,976]	9	hSpCas9	negative selection	5759799
35842417	35842440	17	-	27260156	A375	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6681675470334423	[653]	[1202,1611,1007,1096]	8	hSpCas9	negative selection	5816795
35842377	35842400	17	-	27260156	A375	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.03775944159768063	[884]	[917,1273,1091,992]	0	hSpCas9	negative selection	5816796
35838510	35838533	17	+	27260156	A375	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.27349708907276254	[761]	[975,746,609,625]	-4	hSpCas9	negative selection	5881049
35838484	35838507	17	-	27260156	A375	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7414927226712525	[466]	[1037,909,813,885]	9	hSpCas9	negative selection	5881050
35842417	35842440	17	-	27260156	COLO741	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.39446983946467506	[653]	[1164,1017,1113]	7	hSpCas9	negative selection	5938046
35842377	35842400	17	-	27260156	COLO741	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.09373690496627474	[884]	[1225,1242,1153]	2	hSpCas9	negative selection	5938047
35838510	35838533	17	+	27260156	COLO741	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.22434637962963166	[761]	[1205,1205,1012]	5	hSpCas9	negative selection	6002300
35838484	35838507	17	-	27260156	COLO741	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6916083417435845	[466]	[981,1021,891]	9	hSpCas9	negative selection	6002301
35842417	35842440	17	-	27260156	CAL120	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.7004525343966941	[653]	[1127,1618,1192]	8	hSpCas9	negative selection	6059297
35842377	35842400	17	-	27260156	CAL120	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.29257706672849515	[884]	[1573,1103,1400]	4	hSpCas9	negative selection	6059298
35838510	35838533	17	+	27260156	CAL120	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.796852583150986	[761]	[2186,1882,964]	9	hSpCas9	negative selection	6123551
35838484	35838507	17	-	27260156	CAL120	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.8325789905131467	[466]	[759,1326,976]	9	hSpCas9	negative selection	6123552
35842417	35842440	17	-	27260156	CADOES1	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.45708302901469977	[653]	[856,866,780,834]	7	hSpCas9	negative selection	6180548
35842377	35842400	17	-	27260156	CADOES1	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.10261779648349989	[884]	[551,1068,1115,795]	1	hSpCas9	negative selection	6180549
35838510	35838533	17	+	27260156	CADOES1	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.16068312710342825	[761]	[688,849,816,813]	2	hSpCas9	negative selection	6244802
35838484	35838507	17	-	27260156	CADOES1	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6964230949405851	[466]	[812,700,471,833]	9	hSpCas9	negative selection	6244803
35842417	35842440	17	-	27260156	EWS502	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5270539341909319	[653]	[850,986,1069,1107]	8	hSpCas9	negative selection	6301799
35842377	35842400	17	-	27260156	EWS502	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.07804098576985075	[884]	[936,941,1188,889]	1	hSpCas9	negative selection	6301800
35838510	35838533	17	+	27260156	EWS502	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.24991296397254337	[761]	[999,899,988,942]	4	hSpCas9	negative selection	6366053
35838484	35838507	17	-	27260156	EWS502	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.8364640722397237	[466]	[773,986,906,869]	9	hSpCas9	negative selection	6366054
35842417	35842440	17	-	27260156	EW8	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5792874339988143	[653]	[928,761,638,875]	8	hSpCas9	negative selection	6423050
35842377	35842400	17	-	27260156	EW8	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.08506041049832269	[884]	[622,676,709,680]	-1	hSpCas9	negative selection	6423051
35838510	35838533	17	+	27260156	EW8	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.2830957185855705	[761]	[773,888,565,808]	5	hSpCas9	negative selection	6487304
35838484	35838507	17	-	27260156	EW8	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7568901269454985	[466]	[624,562,681,676]	9	hSpCas9	negative selection	6487305
35842417	35842440	17	-	27260156	CORL105	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6160513405521195	[653]	[1135,1134,1569,914]	9	hSpCas9	negative selection	6544301
35842377	35842400	17	-	27260156	CORL105	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.021238650343328502	[884]	[974,1051,1242,962]	0	hSpCas9	negative selection	6544302
35838510	35838533	17	+	27260156	CORL105	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.029070781657356548	[761]	[956,885,1011,803]	0	hSpCas9	negative selection	6608555
35838484	35838507	17	-	27260156	CORL105	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.4632978668996419	[466]	[803,677,879,675]	8	hSpCas9	negative selection	6608556
35842417	35842440	17	-	27260156	HS294T	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5759791839359703	[653]	[347,401,363,397]	7	hSpCas9	negative selection	6665552
35842377	35842400	17	-	27260156	HS294T	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.2618322515578805	[884]	[210,211,298,456]	-4	hSpCas9	negative selection	6665553
35838510	35838533	17	+	27260156	HS294T	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.0814247328367339	[761]	[145,304,369,308]	-1	hSpCas9	negative selection	6729806
35838484	35838507	17	-	27260156	HS294T	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7207682757181877	[466]	[327,256,243,370]	8	hSpCas9	negative selection	6729807
35842417	35842440	17	-	27260156	HCC44	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5211224331956568	[653]	[1067,815,1461,997]	8	hSpCas9	negative selection	6786803
35842377	35842400	17	-	27260156	HCC44	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.23757536541531132	[884]	[995,831,845,733]	-4	hSpCas9	negative selection	6786804
35838510	35838533	17	+	27260156	HCC44	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.008487972813638223	[761]	[653,583,1114,1122]	0	hSpCas9	negative selection	6851057
35838484	35838507	17	-	27260156	HCC44	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6396137576573068	[466]	[998,555,1026,792]	9	hSpCas9	negative selection	6851058
35842417	35842440	17	-	27260156	G402	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.31014305790022234	[653]	[917,1233,759,1042]	4	hSpCas9	negative selection	6908054
35842377	35842400	17	-	27260156	G402	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.03850405163470505	[884]	[1109,1060,1206,842]	0	hSpCas9	negative selection	6908055
35838510	35838533	17	+	27260156	G402	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.12154357382196068	[761]	[1026,693,602,1094]	-1	hSpCas9	negative selection	6972308
35838484	35838507	17	-	27260156	G402	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.2694713383559203	[466]	[763,595,626,759]	3	hSpCas9	negative selection	6972309
35842417	35842440	17	-	27260156	L33	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6696415492488121	[653]	[1048,380,661,1127]	9	hSpCas9	negative selection	7029305
35842377	35842400	17	-	27260156	L33	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.10163737105092696	[884]	[992,421,525,936]	2	hSpCas9	negative selection	7029306
35838510	35838533	17	+	27260156	L33	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.019271322418477288	[761]	[714,326,470,745]	0	hSpCas9	negative selection	7093559
35838484	35838507	17	-	27260156	L33	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.27501764470622825	[466]	[571,278,332,477]	6	hSpCas9	negative selection	7093560
35842417	35842440	17	-	27260156	K562	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6995211163840398	[653]	[1150,1321,924,461]	8	hSpCas9	negative selection	7150556
35842377	35842400	17	-	27260156	K562	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.32633148794924194	[884]	[1097,1307,721,848]	4	hSpCas9	negative selection	7150557
35838510	35838533	17	+	27260156	K562	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.3533498226114443	[761]	[1018,814,1150,517]	4	hSpCas9	negative selection	7214810
35838484	35838507	17	-	27260156	K562	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	1.4405031040777163	[466]	[1183,795,574,1841]	9	hSpCas9	negative selection	7214811
35842417	35842440	17	-	27260156	HT29	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.6356166950788449	[653]	[1267,1339,1332,1027]	9	hSpCas9	negative selection	7271807
35842377	35842400	17	-	27260156	HT29	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.0725846536034287	[884]	[998,874,1225,975]	-1	hSpCas9	negative selection	7271808
35838510	35838533	17	+	27260156	HT29	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.06035579709393213	[761]	[1103,913,1016,842]	1	hSpCas9	negative selection	7336061
35838484	35838507	17	-	27260156	HT29	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5981062397172736	[466]	[884,831,955,768]	9	hSpCas9	negative selection	7336062
35842417	35842440	17	-	27260156	MHHES1	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.8627502569197423	[653]	[1352,1597,1109,1300]	9	hSpCas9	negative selection	7393058
35842377	35842400	17	-	27260156	MHHES1	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.18183489909524087	[884]	[1436,1374,907,892]	3	hSpCas9	negative selection	7393059
35838510	35838533	17	+	27260156	MHHES1	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.14613189973022722	[761]	[950,929,980,919]	2	hSpCas9	negative selection	7457312
35838484	35838507	17	-	27260156	MHHES1	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.4754949226715783	[466]	[977,761,764,492]	8	hSpCas9	negative selection	7457313
35842417	35842440	17	-	27260156	MEWO	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5254785503700852	[653]	[1092,895,693]	9	hSpCas9	negative selection	7514309
35842377	35842400	17	-	27260156	MEWO	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.013548992264546977	[884]	[1021,680,840]	0	hSpCas9	negative selection	7514310
35838510	35838533	17	+	27260156	MEWO	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.0897858613759186	[761]	[973,670,672]	2	hSpCas9	negative selection	7578563
35838484	35838507	17	-	27260156	MEWO	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5519296755112225	[466]	[769,541,634]	9	hSpCas9	negative selection	7578564
35842417	35842440	17	-	27260156	LNCAPCLONEFGC	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.7045792266204896	[653]	[835,813,1128,1118]	9	hSpCas9	negative selection	7635560
35842377	35842400	17	-	27260156	LNCAPCLONEFGC	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.08828753143850776	[884]	[607,741,898,791]	-1	hSpCas9	negative selection	7635561
35838510	35838533	17	+	27260156	LNCAPCLONEFGC	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.04732318204142627	[761]	[663,646,854,712]	0	hSpCas9	negative selection	7699814
35838484	35838507	17	-	27260156	LNCAPCLONEFGC	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7374587499354078	[466]	[554,595,995,726]	9	hSpCas9	negative selection	7699815
35842417	35842440	17	-	27260156	PANC0327	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.640339075976891	[653]	[1670,567,736,751]	8	hSpCas9	negative selection	7756811
35842377	35842400	17	-	27260156	PANC0327	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.2920993097311756	[884]	[780,396,650,781]	-4	hSpCas9	negative selection	7756812
35838510	35838533	17	+	27260156	PANC0327	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.23231510612790612	[761]	[730,692,370,506]	-3	hSpCas9	negative selection	7821065
35838484	35838507	17	-	27260156	PANC0327	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	1.0318554100962054	[466]	[1064,819,811,716]	9	hSpCas9	negative selection	7821066
35842417	35842440	17	-	27260156	NCIH2009	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	1.003033627916436	[653]	[1784,1980,1712]	9	hSpCas9	negative selection	7878062
35842377	35842400	17	-	27260156	NCIH2009	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.2314032323741657	[884]	[1188,1040,954]	-3	hSpCas9	negative selection	7878063
35838510	35838533	17	+	27260156	NCIH2009	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.1287179902214841	[761]	[1081,974,883]	-2	hSpCas9	negative selection	7942316
35838484	35838507	17	-	27260156	NCIH2009	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.4962433849957738	[466]	[930,1115,710]	6	hSpCas9	negative selection	7942317
35842417	35842440	17	-	27260156	NCIH1373	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.9597806362263441	[653]	[2036,1521,845,363]	8	hSpCas9	negative selection	7999313
35842377	35842400	17	-	27260156	NCIH1373	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.19733890389302133	[884]	[1085,608,855,255]	-2	hSpCas9	negative selection	7999314
35838510	35838533	17	+	27260156	NCIH1373	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.3465957770977202	[761]	[888,793,570,114]	-3	hSpCas9	negative selection	8063567
35838484	35838507	17	-	27260156	NCIH1373	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5974791615019842	[466]	[1206,389,818,225]	6	hSpCas9	negative selection	8063568
35842417	35842440	17	-	27260156	PATU8902	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.8704883444820972	[653]	[1142,1652,1936,1875]	8	hSpCas9	negative selection	8120564
35842377	35842400	17	-	27260156	PATU8902	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.31745248619648814	[884]	[530,1098,654,1860]	-3	hSpCas9	negative selection	8120565
35838510	35838533	17	+	27260156	PATU8902	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.4533877163105908	[761]	[1063,656,656,737]	-4	hSpCas9	negative selection	8184818
35838484	35838507	17	-	27260156	PATU8902	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.9192079188307467	[466]	[1748,1095,839,1330]	8	hSpCas9	negative selection	8184819
35842417	35842440	17	-	27260156	PANC1	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.4977402318215217	[653]	[758,1286,634,609]	7	hSpCas9	negative selection	8241815
35842377	35842400	17	-	27260156	PANC1	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.1112755075666716	[884]	[730,690,815,582]	-2	hSpCas9	negative selection	8241816
35838510	35838533	17	+	27260156	PANC1	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.059227802534521756	[761]	[619,666,667,565]	-1	hSpCas9	negative selection	8306069
35838484	35838507	17	-	27260156	PANC1	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6501103704604383	[466]	[567,980,539,510]	9	hSpCas9	negative selection	8306070
35842417	35842440	17	-	27260156	PANC0813	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5713657815826203	[653]	[1089,1152,1199,1117]	8	hSpCas9	negative selection	8363066
35842377	35842400	17	-	27260156	PANC0813	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.6121565006822609	[884]	[734,683,743,567]	-7	hSpCas9	negative selection	8363067
35838510	35838533	17	+	27260156	PANC0813	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.714466392362483	[761]	[672,422,706,398]	-7	hSpCas9	negative selection	8427320
35838484	35838507	17	-	27260156	PANC0813	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.40710899008640433	[466]	[869,729,508,806]	6	hSpCas9	negative selection	8427321
35842417	35842440	17	-	27260156	RDES	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.8119463299705565	[653]	[1323,1101,1228,1648]	9	hSpCas9	negative selection	8484317
35842377	35842400	17	-	27260156	RDES	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.11393288783764821	[884]	[709,810,1196,1115]	-2	hSpCas9	negative selection	8484318
35838510	35838533	17	+	27260156	RDES	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.26560333255440804	[761]	[773,1065,1117,1328]	4	hSpCas9	negative selection	8548571
35838484	35838507	17	-	27260156	RDES	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7188667546384714	[466]	[652,890,956,1092]	9	hSpCas9	negative selection	8548572
35842417	35842440	17	-	27260156	PC3	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.24971855755374484	[653]	[474,554,1629,848]	5	hSpCas9	negative selection	8605568
35842377	35842400	17	-	27260156	PC3	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.062675527571315	[884]	[687,830,1367,976]	1	hSpCas9	negative selection	8605569
35838510	35838533	17	+	27260156	PC3	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.09724669163401778	[761]	[448,658,1266,730]	-2	hSpCas9	negative selection	8669822
35838484	35838507	17	-	27260156	PC3	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6640044153156022	[466]	[438,688,1269,828]	9	hSpCas9	negative selection	8669823
35842417	35842440	17	-	27260156	PATU8988T	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.27777085736188367	[653]	[775,873,561,873]	5	hSpCas9	negative selection	8726819
35842377	35842400	17	-	27260156	PATU8988T	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.14486531184946327	[884]	[1091,781,746,1165]	2	hSpCas9	negative selection	8726820
35838510	35838533	17	+	27260156	PATU8988T	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.034260414814682116	[761]	[570,521,787,997]	0	hSpCas9	negative selection	8791073
35838484	35838507	17	-	27260156	PATU8988T	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6099994453843105	[466]	[756,676,597,725]	8	hSpCas9	negative selection	8791074
35842417	35842440	17	-	27260156	T47D	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5711213013764278	[653]	[1291,1039,1092,1110]	9	hSpCas9	negative selection	8848070
35842377	35842400	17	-	27260156	T47D	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.004678645485021171	[884]	[1071,934,894,1224]	0	hSpCas9	negative selection	8848071
35838510	35838533	17	+	27260156	T47D	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	-0.05255826507784789	[761]	[953,757,810,911]	-1	hSpCas9	negative selection	8912324
35838484	35838507	17	-	27260156	T47D	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6605682240664303	[466]	[793,913,856,869]	9	hSpCas9	negative selection	8912325
35842417	35842440	17	-	27260156	SU8686	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.9116635941444893	[653]	[1012,1172,1299,1453]	9	hSpCas9	negative selection	8969321
35842377	35842400	17	-	27260156	SU8686	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.2629524109909277	[884]	[626,681,805,842]	-4	hSpCas9	negative selection	8969322
35838510	35838533	17	+	27260156	SU8686	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.06916021943614381	[761]	[624,761,725,1126]	1	hSpCas9	negative selection	9033575
35838484	35838507	17	-	27260156	SU8686	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5922807020664315	[466]	[685,649,732,731]	8	hSpCas9	negative selection	9033576
35842417	35842440	17	-	27260156	SKES1	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.43715878140906794	[653]	[924,917,821,870]	8	hSpCas9	negative selection	9090572
35842377	35842400	17	-	27260156	SKES1	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.23065421681498355	[884]	[1216,1107,1054,812]	5	hSpCas9	negative selection	9090573
35838510	35838533	17	+	27260156	SKES1	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.2850381352800936	[761]	[1359,942,810,674]	6	hSpCas9	negative selection	9154826
35838484	35838507	17	-	27260156	SKES1	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.6527485961844909	[466]	[728,782,641,769]	9	hSpCas9	negative selection	9154827
35842417	35842440	17	-	27260156	TOV112D	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.5157448184041905	[653]	[624,1001,1231,876]	8	hSpCas9	negative selection	9211823
35842377	35842400	17	-	27260156	TOV112D	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	-0.21748497094896246	[884]	[951,767,566,777]	-4	hSpCas9	negative selection	9211824
35838510	35838533	17	+	27260156	TOV112D	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.3902498904118311	[761]	[1216,1236,917,711]	7	hSpCas9	negative selection	9276077
35838484	35838507	17	-	27260156	TOV112D	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.7414786077068516	[466]	[768,1139,607,698]	9	hSpCas9	negative selection	9276078
35842417	35842440	17	-	27260156	TC71	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.43484440548642644	[653]	[959,1121,857,846]	8	hSpCas9	negative selection	9333074
35842377	35842400	17	-	27260156	TC71	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.09719419576765442	[884]	[1056,904,899,1211]	2	hSpCas9	negative selection	9333075
35838510	35838533	17	+	27260156	TC71	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.2854701919698286	[761]	[1121,811,943,1109]	7	hSpCas9	negative selection	9397328
35838484	35838507	17	-	27260156	TC71	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5008382555243225	[466]	[527,772,710,832]	9	hSpCas9	negative selection	9397329
35842417	35842440	17	-	27260156	TC32	viability	CCACCTCCTCTCATGAATTCAGG	TAF15	ENSG00000270647	0.633791114135394	[653]	[887,650,1369,1050]	9	hSpCas9	negative selection	9454325
35842377	35842400	17	-	27260156	TC32	viability	ACACTTTAATGATGTTGCCATGG	TAF15	ENSG00000270647	0.2400258616283878	[884]	[805,829,1341,1036]	4	hSpCas9	negative selection	9454326
35838510	35838533	17	+	27260156	TC32	viability	TGATGACCCTCCTTCAGCTAAGG	TAF15	ENSG00000270647	0.35776958900549516	[761]	[877,594,1278,1063]	6	hSpCas9	negative selection	9518579
35838484	35838507	17	-	27260156	TC32	viability	GACACTGTTGCCTCCCCCTTTGG	TAF15	ENSG00000270647	0.5556673193754271	[466]	[551,435,974,733]	8	hSpCas9	negative selection	9518580
35842417	35842440	17	+	27869803	HPAFII	viability after 27 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.7219809755997848	[153]	[264,23,NaN]	6	hSpCas9	negative selection	9560141
35844097	35844120	17	+	27869803	HPAFII	viability after 27 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.4612199560710478	[567]	[325,125,NaN]	-3	hSpCas9	negative selection	9560142
35844487	35844510	17	+	27869803	HPAFII	viability after 27 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.16597972178663423	[193]	[13,154,NaN]	-1	hSpCas9	negative selection	9560143
35842417	35842440	17	+	27869803	HPAFII	viability after 15 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.2121690655490942	[153]	[327,106,NaN]	2	hSpCas9	negative selection	9642590
35844097	35844120	17	+	27869803	HPAFII	viability after 15 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.053420632352960906	[567]	[1001,330,NaN]	0	hSpCas9	negative selection	9642591
35844487	35844510	17	+	27869803	HPAFII	viability after 15 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.22319324876294722	[193]	[140,201,NaN]	-3	hSpCas9	negative selection	9642592
35842417	35842440	17	+	27869803	ASPC1	viability after 36 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	0.2985239926522718	[513]	[483,0,207]	3	hSpCas9	negative selection	9725039
35844097	35844120	17	+	27869803	ASPC1	viability after 36 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.44739091304214695	[1386]	[509,728,703]	4	hSpCas9	negative selection	9725040
35844487	35844510	17	+	27869803	ASPC1	viability after 36 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.020371353160528738	[434]	[207,102,154]	0	hSpCas9	negative selection	9725041
35842417	35842440	17	+	27869803	PATU8988S	viability after 35 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.3608529053229921	[334]	[132,76,NaN]	-4	hSpCas9	negative selection	9807488
35844097	35844120	17	+	27869803	PATU8988S	viability after 35 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.11701846216467371	[1255]	[370,726,NaN]	1	hSpCas9	negative selection	9807489
35844487	35844510	17	+	27869803	PATU8988S	viability after 35 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.8133640491183209	[371]	[387,137,NaN]	8	hSpCas9	negative selection	9807490
35842417	35842440	17	+	27869803	PATU8988S	viability after 31 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	-0.053470888800987826	[334]	[122,135,NaN]	0	hSpCas9	negative selection	9889937
35844097	35844120	17	+	27869803	PATU8988S	viability after 31 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.15793044167824855	[1255]	[362,807,NaN]	2	hSpCas9	negative selection	9889938
35844487	35844510	17	+	27869803	PATU8988S	viability after 31 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	0.18797486842018635	[371]	[241,75,NaN]	2	hSpCas9	negative selection	9889939
35842417	35842440	17	+	27869803	HPAFII	viability after 35 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	1.2932979785184542	[153]	[342,19,NaN]	8	hSpCas9	negative selection	9972386
35844097	35844120	17	+	27869803	HPAFII	viability after 35 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	0.22319858693503614	[567]	[480,171,NaN]	1	hSpCas9	negative selection	9972387
35844487	35844510	17	+	27869803	HPAFII	viability after 35 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.2455355999722314	[193]	[0,174,NaN]	-1	hSpCas9	negative selection	9972388
35842417	35842440	17	+	27869803	HPAFII	viability after 31 days	CCTGAATTCATGAGAGGAGGTGG	TAF15	ENSG00000270647	1.1181006766083705	[153]	[334,26,NaN]	8	hSpCas9	negative selection	10054835
35844097	35844120	17	+	27869803	HPAFII	viability after 31 days	CGTGGAGGCTTTCAAGGGAGAGG	TAF15	ENSG00000270647	-0.016873503922321786	[567]	[416,203,NaN]	0	hSpCas9	negative selection	10054836
35844487	35844510	17	+	27869803	HPAFII	viability after 31 days	GAGAGGCTACGGTGGAGAGAGGG	TAF15	ENSG00000270647	-0.4706087561574521	[193]	[1,161,NaN]	-3	hSpCas9	negative selection	10054837
35844100	35844123	17	+	28162770	P31FUJ	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.7150384035811226	[270]	[193]	-5	hSpCas9	negative selection	10246777
35844710	35844733	17	+	28162770	P31FUJ	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.4027272058566913	[8]	[0]	-9	hSpCas9	negative selection	10246778
35844581	35844604	17	+	28162770	P31FUJ	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.2936844465614012	[120]	[57]	-7	hSpCas9	negative selection	10246779
35844082	35844105	17	+	28162770	P31FUJ	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.5444005208605509	[296]	[508]	6	hSpCas9	negative selection	10246780
35844344	35844367	17	+	28162770	P31FUJ	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.6837864000996139	[297]	[217]	-5	hSpCas9	negative selection	10246781
35844356	35844379	17	-	28162770	P31FUJ	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.9627861981694863	[480]	[289]	-6	hSpCas9	negative selection	10246782
35844503	35844526	17	+	28162770	P31FUJ	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.05407894337378308	[249]	[304]	0	hSpCas9	negative selection	10246783
35844527	35844550	17	+	28162770	P31FUJ	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-4.0272180707644845	[110]	[7]	-9	hSpCas9	negative selection	10246784
35844662	35844685	17	+	28162770	P31FUJ	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-1.2792126693713366	[536]	[259]	-7	hSpCas9	negative selection	10246785
35844100	35844123	17	+	28162770	TF1	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10416143
35844710	35844733	17	+	28162770	TF1	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10416144
35844581	35844604	17	+	28162770	TF1	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10416145
35844082	35844105	17	+	28162770	TF1	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10416146
35844344	35844367	17	+	28162770	TF1	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10416147
35844356	35844379	17	-	28162770	TF1	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	NaN	[NaN]	[304]	1	hSpCas9	negative selection	10416148
35844503	35844526	17	+	28162770	TF1	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10416149
35844527	35844550	17	+	28162770	TF1	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10416150
35844662	35844685	17	+	28162770	TF1	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10416151
35844100	35844123	17	+	28162770	SKM1	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	0.011537155839253577	[77]	[138]	0	hSpCas9	negative selection	10585509
35844710	35844733	17	+	28162770	SKM1	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10585510
35844581	35844604	17	+	28162770	SKM1	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10585511
35844082	35844105	17	+	28162770	SKM1	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.2470928619647722	[95]	[142]	-2	hSpCas9	negative selection	10585512
35844344	35844367	17	+	28162770	SKM1	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.835422213784327	[107]	[106]	-6	hSpCas9	negative selection	10585513
35844356	35844379	17	-	28162770	SKM1	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-1.4289905050731606	[98]	[64]	-7	hSpCas9	negative selection	10585514
35844503	35844526	17	+	28162770	SKM1	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.0234883529223697	[63]	[114]	0	hSpCas9	negative selection	10585515
35844527	35844550	17	+	28162770	SKM1	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-5.7288922936305235	[29]	[0]	-9	hSpCas9	negative selection	10585516
35844662	35844685	17	+	28162770	SKM1	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.9563027897335964	[134]	[122]	-6	hSpCas9	negative selection	10585517
35844100	35844123	17	+	28162770	SKM1	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	0.011537155839253577	[77]	[138]	0	hSpCas9	negative selection	10754875
35844710	35844733	17	+	28162770	SKM1	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	0.17799830197799427	[2]	[5]	1	hSpCas9	negative selection	10754876
35844581	35844604	17	+	28162770	SKM1	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10754877
35844082	35844105	17	+	28162770	SKM1	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.2470928619647722	[95]	[142]	-2	hSpCas9	negative selection	10754878
35844344	35844367	17	+	28162770	SKM1	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.835422213784327	[107]	[106]	-6	hSpCas9	negative selection	10754879
35844356	35844379	17	-	28162770	SKM1	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-1.4289905050731606	[98]	[64]	-7	hSpCas9	negative selection	10754880
35844503	35844526	17	+	28162770	SKM1	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.0234883529223697	[63]	[114]	0	hSpCas9	negative selection	10754881
35844527	35844550	17	+	28162770	SKM1	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-5.7288922936305235	[29]	[0]	-9	hSpCas9	negative selection	10754882
35844662	35844685	17	+	28162770	SKM1	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.9563027897335964	[134]	[122]	-6	hSpCas9	negative selection	10754883
35844100	35844123	17	+	28162770	PL21	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	0.44114771399311503	[241]	[142]	4	hSpCas9	negative selection	10924241
35844710	35844733	17	+	28162770	PL21	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-2.8873232267610196	[16]	[0]	-9	hSpCas9	negative selection	10924242
35844581	35844604	17	+	28162770	PL21	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.3404287668733825	[127]	[21]	-7	hSpCas9	negative selection	10924243
35844082	35844105	17	+	28162770	PL21	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.42508675644556326	[326]	[105]	-3	hSpCas9	negative selection	10924244
35844344	35844367	17	+	28162770	PL21	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.536825979676886	[329]	[98]	-4	hSpCas9	negative selection	10924245
35844356	35844379	17	-	28162770	PL21	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.6617294666471873	[417]	[114]	-4	hSpCas9	negative selection	10924246
35844503	35844526	17	+	28162770	PL21	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.7407079958520228	[153]	[111]	6	hSpCas9	negative selection	10924247
35844527	35844550	17	+	28162770	PL21	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-3.3646450042942058	[141]	[5]	-9	hSpCas9	negative selection	10924248
35844662	35844685	17	+	28162770	PL21	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.9041970453254156	[429]	[99]	-6	hSpCas9	negative selection	10924249
35844100	35844123	17	+	28162770	P31FUJ	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.7150384035811226	[270]	[193]	-5	hSpCas9	negative selection	11093607
35844710	35844733	17	+	28162770	P31FUJ	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.4027272058566913	[8]	[0]	-9	hSpCas9	negative selection	11093608
35844581	35844604	17	+	28162770	P31FUJ	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.2936844465614012	[120]	[57]	-7	hSpCas9	negative selection	11093609
35844082	35844105	17	+	28162770	P31FUJ	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.5444005208605509	[296]	[508]	6	hSpCas9	negative selection	11093610
35844344	35844367	17	+	28162770	P31FUJ	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.6837864000996139	[297]	[217]	-5	hSpCas9	negative selection	11093611
35844356	35844379	17	-	28162770	P31FUJ	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.9627861981694863	[480]	[289]	-6	hSpCas9	negative selection	11093612
35844503	35844526	17	+	28162770	P31FUJ	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.05407894337378308	[249]	[304]	0	hSpCas9	negative selection	11093613
35844527	35844550	17	+	28162770	P31FUJ	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-4.0272180707644845	[110]	[7]	-9	hSpCas9	negative selection	11093614
35844662	35844685	17	+	28162770	P31FUJ	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-1.2792126693713366	[536]	[259]	-7	hSpCas9	negative selection	11093615
35844100	35844123	17	+	28162770	OCIAML5	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.8093169234046601	[132]	[136]	-5	hSpCas9	negative selection	11262973
35844710	35844733	17	+	28162770	OCIAML5	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.6594214929216013	[6]	[0]	-9	hSpCas9	negative selection	11262974
35844581	35844604	17	+	28162770	OCIAML5	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.3480240655264084	[54]	[38]	-7	hSpCas9	negative selection	11262975
35844082	35844105	17	+	28162770	OCIAML5	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.19017140990797687	[212]	[336]	-1	hSpCas9	negative selection	11262976
35844344	35844367	17	+	28162770	OCIAML5	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.3253186840881365	[117]	[169]	-2	hSpCas9	negative selection	11262977
35844356	35844379	17	-	28162770	OCIAML5	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.21833824314757722	[222]	[345]	-1	hSpCas9	negative selection	11262978
35844503	35844526	17	+	28162770	OCIAML5	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.8199815466208709	[149]	[477]	7	hSpCas9	negative selection	11262979
35844527	35844550	17	+	28162770	OCIAML5	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-7.295010066712726	[86]	[0]	-9	hSpCas9	negative selection	11262980
35844662	35844685	17	+	28162770	OCIAML5	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.8702903294829043	[238]	[235]	-5	hSpCas9	negative selection	11262981
35844100	35844123	17	+	28162770	EOL1	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.22745532187451545	[419]	[188]	-2	hSpCas9	negative selection	11432339
35844710	35844733	17	+	28162770	EOL1	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-1.3973803233168276	[9]	[1]	-7	hSpCas9	negative selection	11432340
35844581	35844604	17	+	28162770	EOL1	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.5084116357055716	[188]	[69]	-4	hSpCas9	negative selection	11432341
35844082	35844105	17	+	28162770	EOL1	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.5017169831315633	[515]	[191]	-4	hSpCas9	negative selection	11432342
35844344	35844367	17	+	28162770	EOL1	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-1.3567383388194818	[524]	[107]	-7	hSpCas9	negative selection	11432343
35844356	35844379	17	-	28162770	EOL1	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.8856276695494482	[511]	[145]	-6	hSpCas9	negative selection	11432344
35844503	35844526	17	+	28162770	EOL1	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.3551821259003969	[275]	[185]	3	hSpCas9	negative selection	11432345
35844527	35844550	17	+	28162770	EOL1	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-5.704808848509075	[98]	[0]	-9	hSpCas9	negative selection	11432346
35844662	35844685	17	+	28162770	EOL1	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-1.0478279807211128	[568]	[144]	-6	hSpCas9	negative selection	11432347
35844100	35844123	17	+	28162770	MOLM13	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	0.09647881466599281	[303]	[234]	0	hSpCas9	negative selection	11601705
35844710	35844733	17	+	28162770	MOLM13	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-2.1170731191765775	[11]	[1]	-7	hSpCas9	negative selection	11601706
35844581	35844604	17	+	28162770	MOLM13	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.8408633245950503	[108]	[43]	-4	hSpCas9	negative selection	11601707
35844082	35844105	17	+	28162770	MOLM13	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	1.1847893526566795	[361]	[594]	8	hSpCas9	negative selection	11601708
35844344	35844367	17	+	28162770	MOLM13	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.09950826972361726	[448]	[302]	0	hSpCas9	negative selection	11601709
35844356	35844379	17	-	28162770	MOLM13	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-2.244534028358836	[543]	[82]	-7	hSpCas9	negative selection	11601710
35844503	35844526	17	+	28162770	MOLM13	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.4233429425913169	[295]	[286]	3	hSpCas9	negative selection	11601711
35844527	35844550	17	+	28162770	MOLM13	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-4.924428041234181	[125]	[2]	-9	hSpCas9	negative selection	11601712
35844662	35844685	17	+	28162770	MOLM13	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-1.7704225948779837	[485]	[102]	-7	hSpCas9	negative selection	11601713
35844100	35844123	17	+	28162770	HEL	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.0800328805830948	[235]	[142]	0	hSpCas9	negative selection	11771071
35844710	35844733	17	+	28162770	HEL	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.2641517636081616	[14]	[0]	-9	hSpCas9	negative selection	11771072
35844581	35844604	17	+	28162770	HEL	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-1.102688340914045	[113]	[33]	-6	hSpCas9	negative selection	11771073
35844082	35844105	17	+	28162770	HEL	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.6466327481048482	[369]	[370]	5	hSpCas9	negative selection	11771074
35844344	35844367	17	+	28162770	HEL	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.28954684940329745	[436]	[228]	-2	hSpCas9	negative selection	11771075
35844356	35844379	17	-	28162770	HEL	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-1.5154806687896765	[490]	[109]	-7	hSpCas9	negative selection	11771076
35844503	35844526	17	+	28162770	HEL	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	-1.0643707780065896	[270]	[82]	-6	hSpCas9	negative selection	11771077
35844527	35844550	17	+	28162770	HEL	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-4.458799194461705	[102]	[2]	-9	hSpCas9	negative selection	11771078
35844662	35844685	17	+	28162770	HEL	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.4567968415505576	[419]	[195]	-3	hSpCas9	negative selection	11771079
35844100	35844123	17	+	28162770	MV411	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-1.538855755746999	[237]	[68]	-7	hSpCas9	negative selection	11940437
35844710	35844733	17	+	28162770	MV411	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	2.706869169420073	[1]	[10]	9	hSpCas9	negative selection	11940438
35844581	35844604	17	+	28162770	MV411	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.825811431247863	[100]	[47]	-5	hSpCas9	negative selection	11940439
35844082	35844105	17	+	28162770	MV411	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.03969971945022066	[337]	[276]	0	hSpCas9	negative selection	11940440
35844344	35844367	17	+	28162770	MV411	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.562180422783398	[318]	[181]	-4	hSpCas9	negative selection	11940441
35844356	35844379	17	-	28162770	MV411	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.603777862496627	[358]	[198]	-4	hSpCas9	negative selection	11940442
35844503	35844526	17	+	28162770	MV411	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.7985751738556656	[186]	[273]	7	hSpCas9	negative selection	11940443
35844527	35844550	17	+	28162770	MV411	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-4.782309792611277	[97]	[2]	-9	hSpCas9	negative selection	11940444
35844662	35844685	17	+	28162770	MV411	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-2.217094939547388	[424]	[76]	-8	hSpCas9	negative selection	11940445
35844100	35844123	17	+	28162770	MONOMAC1	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-1.221149303176361	[180]	[88]	-7	hSpCas9	negative selection	12109803
35844710	35844733	17	+	28162770	MONOMAC1	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	12109804
35844581	35844604	17	+	28162770	MONOMAC1	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.9723305598848595	[88]	[51]	-6	hSpCas9	negative selection	12109805
35844082	35844105	17	+	28162770	MONOMAC1	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.37690424757035035	[218]	[325]	4	hSpCas9	negative selection	12109806
35844344	35844367	17	+	28162770	MONOMAC1	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-0.4718966882901371	[195]	[161]	-4	hSpCas9	negative selection	12109807
35844356	35844379	17	-	28162770	MONOMAC1	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-0.06579231378130113	[188]	[206]	0	hSpCas9	negative selection	12109808
35844503	35844526	17	+	28162770	MONOMAC1	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	0.5932445616391091	[84]	[146]	6	hSpCas9	negative selection	12109809
35844527	35844550	17	+	28162770	MONOMAC1	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-6.197036847059554	[63]	[0]	-9	hSpCas9	negative selection	12109810
35844662	35844685	17	+	28162770	MONOMAC1	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.6205959011842509	[282]	[210]	-5	hSpCas9	negative selection	12109811
35844100	35844123	17	+	28162770	OCIAML2	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.36700719416800365	[46]	[201]	-3	hSpCas9	negative selection	12279169
35844710	35844733	17	+	28162770	OCIAML2	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-2.4706298252421615	[2]	[2]	-8	hSpCas9	negative selection	12279170
35844581	35844604	17	+	28162770	OCIAML2	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	-0.5892743217407802	[18]	[69]	-4	hSpCas9	negative selection	12279171
35844082	35844105	17	+	28162770	OCIAML2	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	-0.06182427967483217	[57]	[307]	0	hSpCas9	negative selection	12279172
35844344	35844367	17	+	28162770	OCIAML2	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	-1.013584799441742	[54]	[150]	-6	hSpCas9	negative selection	12279173
35844356	35844379	17	-	28162770	OCIAML2	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-1.4611694959930948	[75]	[152]	-7	hSpCas9	negative selection	12279174
35844503	35844526	17	+	28162770	OCIAML2	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	-0.06663059741576566	[40]	[216]	0	hSpCas9	negative selection	12279175
35844527	35844550	17	+	28162770	OCIAML2	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-6.377520420850679	[14]	[0]	-9	hSpCas9	negative selection	12279176
35844662	35844685	17	+	28162770	OCIAML2	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.885667324521005	[58]	[176]	-6	hSpCas9	negative selection	12279177
35844100	35844123	17	+	28162770	OCIAML3	viability	GGAGGCTTTCAAGGGAGAGGTGG	TAF15	ENSG00000270647	-0.23596011963014893	[70]	[181]	-2	hSpCas9	negative selection	12448535
35844710	35844733	17	+	28162770	OCIAML3	viability	TATGGAGGAGACCGAGGAGGTGG	TAF15	ENSG00000270647	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12448536
35844581	35844604	17	+	28162770	OCIAML3	viability	GGTGGAGACAGAAGCAGCGGTGG	TAF15	ENSG00000270647	0.7141146550381686	[20]	[103]	6	hSpCas9	negative selection	12448537
35844082	35844105	17	+	28162770	OCIAML3	viability	GGAGGATATAGAGGTCGTGGAGG	TAF15	ENSG00000270647	0.9585333827046157	[74]	[439]	8	hSpCas9	negative selection	12448538
35844344	35844367	17	+	28162770	OCIAML3	viability	GAGGACTCTCGTCCCTCAGGAGG	TAF15	ENSG00000270647	0.22996199558433705	[110]	[392]	2	hSpCas9	negative selection	12448539
35844356	35844379	17	-	28162770	OCIAML3	viability	GCTGACCCACCTCCTCCTGAGGG	TAF15	ENSG00000270647	-1.9939382472127987	[94]	[71]	-8	hSpCas9	negative selection	12448540
35844503	35844526	17	+	28162770	OCIAML3	viability	GAGAGGGGCTACAGAGGTCGTGG	TAF15	ENSG00000270647	-0.028944697040711675	[72]	[215]	0	hSpCas9	negative selection	12448541
35844527	35844550	17	+	28162770	OCIAML3	viability	GGCAGAGGTGGAGACCGAGGCGG	TAF15	ENSG00000270647	-2.594007640324163	[21]	[10]	-9	hSpCas9	negative selection	12448542
35844662	35844685	17	+	28162770	OCIAML3	viability	TATGGTGGGGACAGAGGCGGCGG	TAF15	ENSG00000270647	-0.1173948619243661	[128]	[358]	-1	hSpCas9	negative selection	12448543