Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7074
• Symbol: TIAM1
• Description: TIAM Rac1 associated GEF 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TIAM1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
31266859	31266882	21	-	26472758	Jiyoye	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.48624695249707217	[70]	[74]	3	hSpCas9	negative selection	165427
31251773	31251796	21	-	26472758	Jiyoye	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-1.5244376435138762	[102]	[26]	-7	hSpCas9	negative selection	165428
31252170	31252193	21	-	26472758	Jiyoye	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	2.202355589617375	[16]	[58]	9	hSpCas9	negative selection	165429
31266823	31266846	21	+	26472758	Jiyoye	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	1.6551028949494588	[47]	[113]	8	hSpCas9	negative selection	165430
31266582	31266605	21	-	26472758	Jiyoye	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	2.185617611648239	[71]	[246]	9	hSpCas9	negative selection	165431
31252024	31252047	21	-	26472758	Jiyoye	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-2.914752713381489	[59]	[5]	-9	hSpCas9	negative selection	165432
31252010	31252033	21	+	26472758	Jiyoye	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.258031942200064	[111]	[100]	2	hSpCas9	negative selection	165433
31251985	31252008	21	-	26472758	Jiyoye	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.2528472351145796	[68]	[61]	2	hSpCas9	negative selection	165434
31251943	31251966	21	-	26472758	Jiyoye	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	5.53645839845084	[0]	[34]	9	hSpCas9	negative selection	165435
31251793	31251816	21	-	26472758	Jiyoye	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	6.107615099646965	[0]	[51]	9	hSpCas9	negative selection	165436
31266859	31266882	21	-	26472758	KBM7	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.48504387661270404	[423,255]	[328,120]	5	hSpCas9	negative selection	356545
31251773	31251796	21	-	26472758	KBM7	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	1.0619319932093094	[205,88]	[193,90]	9	hSpCas9	negative selection	356546
31252170	31252193	21	-	26472758	KBM7	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	-0.2313931142086174	[452,260]	[153,126]	-2	hSpCas9	negative selection	356547
31266823	31266846	21	+	26472758	KBM7	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.8130179353317882	[300,153]	[198,167]	8	hSpCas9	negative selection	356548
31266582	31266605	21	-	26472758	KBM7	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.711947298586692	[793,701]	[607,545]	7	hSpCas9	negative selection	356549
31252024	31252047	21	-	26472758	KBM7	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-1.0034739082833215	[148,81]	[27,24]	-6	hSpCas9	negative selection	356550
31252010	31252033	21	+	26472758	KBM7	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	1.071960670288352	[504,334]	[491,333]	9	hSpCas9	negative selection	356551
31251985	31252008	21	-	26472758	KBM7	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.024273713918054718	[407,289]	[243,93]	0	hSpCas9	negative selection	356552
31251943	31251966	21	-	26472758	KBM7	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.935500741763614	[122,152]	[133,118]	8	hSpCas9	negative selection	356553
31251793	31251816	21	-	26472758	KBM7	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	1.0224985579627277	[315,383]	[258,410]	9	hSpCas9	negative selection	356554
31266859	31266882	21	-	26472758	Raji	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.6396045740227824	[129]	[46]	6	hSpCas9	negative selection	547663
31251773	31251796	21	-	26472758	Raji	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	0.2814129351486486	[155]	[43]	2	hSpCas9	negative selection	547664
31252170	31252193	21	-	26472758	Raji	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.3614291579801385	[160]	[47]	3	hSpCas9	negative selection	547665
31266823	31266846	21	+	26472758	Raji	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.8466193031646329	[126]	[52]	7	hSpCas9	negative selection	547666
31266582	31266605	21	-	26472758	Raji	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.7029932802942641	[359]	[135]	6	hSpCas9	negative selection	547667
31252024	31252047	21	-	26472758	Raji	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	1.8536269431278163	[30]	[25]	9	hSpCas9	negative selection	547668
31252010	31252033	21	+	26472758	Raji	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	-0.7833873948716422	[355]	[47]	-5	hSpCas9	negative selection	547669
31251985	31252008	21	-	26472758	Raji	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.8747227785833246	[93]	[39]	7	hSpCas9	negative selection	547670
31251943	31251966	21	-	26472758	Raji	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.4255594953998545	[76]	[23]	4	hSpCas9	negative selection	547671
31251793	31251816	21	-	26472758	Raji	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-1.1755504278978994	[145]	[14]	-7	hSpCas9	negative selection	547672
31266859	31266882	21	-	26472758	K562	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	-0.21066349050779942	[206]	[150]	-1	hSpCas9	negative selection	738781
31251773	31251796	21	-	26472758	K562	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.3405437730547092	[161]	[107]	-2	hSpCas9	negative selection	738782
31252170	31252193	21	-	26472758	K562	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.8274941188433377	[254]	[381]	7	hSpCas9	negative selection	738783
31266823	31266846	21	+	26472758	K562	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.10040976933099421	[126]	[99]	0	hSpCas9	negative selection	738784
31266582	31266605	21	-	26472758	K562	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.49221325543994787	[570]	[677]	4	hSpCas9	negative selection	738785
31252024	31252047	21	-	26472758	K562	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.47547335314081796	[55]	[33]	-3	hSpCas9	negative selection	738786
31252010	31252033	21	+	26472758	K562	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.17599358665556286	[366]	[349]	1	hSpCas9	negative selection	738787
31251985	31252008	21	-	26472758	K562	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.9632369751223935	[143]	[236]	7	hSpCas9	negative selection	738788
31251943	31251966	21	-	26472758	K562	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	-0.5145731728297582	[241]	[142]	-3	hSpCas9	negative selection	738789
31251793	31251816	21	-	26472758	K562	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-1.180714649347904	[238]	[88]	-6	hSpCas9	negative selection	738790
31210111	31210134	21	+	26627737	DLD1	viability	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.06295959573911014	[787]	[336,288,161]	0	hSpCas9	negative selection	815972
31217625	31217648	21	-	26627737	DLD1	viability	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.37672417014101134	[1034]	[207,277,260]	-4	hSpCas9	negative selection	815973
31223447	31223470	21	-	26627737	DLD1	viability	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	1.068124650552166	[301]	[239,212,148]	8	hSpCas9	negative selection	815974
31225866	31225889	21	-	26627737	DLD1	viability	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.6552350525180966	[436]	[95,374,185]	6	hSpCas9	negative selection	815975
31252045	31252068	21	+	26627737	DLD1	viability	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.7904537219424606	[782]	[239,32,145]	-6	hSpCas9	negative selection	815976
31266354	31266377	21	-	26627737	DLD1	viability	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.7075381821190075	[485]	[278,210,251]	7	hSpCas9	negative selection	815977
31210111	31210134	21	+	26627737	GBM cells	viability after 5 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	-0.3344697244098511	[548]	[244,221]	-5	hSpCas9	negative selection	898287
31217625	31217648	21	-	26627737	GBM cells	viability after 5 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.02648118910990649	[357]	[233,142]	0	hSpCas9	negative selection	898288
31223447	31223470	21	-	26627737	GBM cells	viability after 5 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.6677089504122494	[259]	[167,274]	8	hSpCas9	negative selection	898289
31225866	31225889	21	-	26627737	GBM cells	viability after 5 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.3819281679805362	[170]	[139,98]	6	hSpCas9	negative selection	898290
31252045	31252068	21	+	26627737	GBM cells	viability after 5 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.43602485734485824	[234]	[131,208]	6	hSpCas9	negative selection	898291
31266354	31266377	21	-	26627737	GBM cells	viability after 5 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.3326327952306044	[210]	[139,144]	5	hSpCas9	negative selection	898292
31210111	31210134	21	+	26627737	GBM cells	viability after 13 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	-0.25979328858016115	[548]	[309,198]	-3	hSpCas9	negative selection	980602
31217625	31217648	21	-	26627737	GBM cells	viability after 13 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.05232433830961475	[357]	[215,163]	0	hSpCas9	negative selection	980603
31223447	31223470	21	-	26627737	GBM cells	viability after 13 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.3898547211667624	[259]	[132,226]	5	hSpCas9	negative selection	980604
31225866	31225889	21	-	26627737	GBM cells	viability after 13 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.4076272995835897	[170]	[132,114]	5	hSpCas9	negative selection	980605
31252045	31252068	21	+	26627737	GBM cells	viability after 13 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.7097949858429141	[234]	[191,221]	8	hSpCas9	negative selection	980606
31266354	31266377	21	-	26627737	GBM cells	viability after 13 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.8180596224008463	[210]	[224,182]	8	hSpCas9	negative selection	980607
31210111	31210134	21	+	26627737	GBM cells	viability after 21 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	-0.1425451749512181	[548]	[288,252]	-1	hSpCas9	negative selection	1062917
31217625	31217648	21	-	26627737	GBM cells	viability after 21 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.3587994498992887	[357]	[274,225]	4	hSpCas9	negative selection	1062918
31223447	31223470	21	-	26627737	GBM cells	viability after 21 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	1.205560667288116	[259]	[342,309]	9	hSpCas9	negative selection	1062919
31225866	31225889	21	-	26627737	GBM cells	viability after 21 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.6569187837145606	[170]	[146,145]	6	hSpCas9	negative selection	1062920
31252045	31252068	21	+	26627737	GBM cells	viability after 21 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.47123133563051023	[234]	[188,165]	5	hSpCas9	negative selection	1062921
31266354	31266377	21	-	26627737	GBM cells	viability after 21 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.1474400878632947	[210]	[278,230]	9	hSpCas9	negative selection	1062922
31210111	31210134	21	+	26627737	RPE1	viability after 9 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.1977033785568605	[939]	[185,532]	1	hSpCas9	negative selection	1145232
31217625	31217648	21	-	26627737	RPE1	viability after 9 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.15773374529416095	[994]	[281,431]	1	hSpCas9	negative selection	1145233
31223447	31223470	21	-	26627737	RPE1	viability after 9 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.27611690152500273	[861]	[345,301]	2	hSpCas9	negative selection	1145234
31225866	31225889	21	-	26627737	RPE1	viability after 9 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.2041131894400715	[984]	[175,385]	-1	hSpCas9	negative selection	1145235
31252045	31252068	21	+	26627737	RPE1	viability after 9 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.18054116538418344	[695]	[249,242]	1	hSpCas9	negative selection	1145236
31266354	31266377	21	-	26627737	RPE1	viability after 9 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.424873209937631	[527]	[352,560]	7	hSpCas9	negative selection	1145237
31210111	31210134	21	+	26627737	RPE1	viability after 12 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.10371948902150901	[939]	[181,365]	0	hSpCas9	negative selection	1227547
31217625	31217648	21	-	26627737	RPE1	viability after 12 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.17630926831615212	[994]	[204,269]	-1	hSpCas9	negative selection	1227548
31223447	31223470	21	-	26627737	RPE1	viability after 12 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.12102918984661737	[861]	[246,256]	0	hSpCas9	negative selection	1227549
31225866	31225889	21	-	26627737	RPE1	viability after 12 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.32928004163699925	[984]	[263,404]	2	hSpCas9	negative selection	1227550
31252045	31252068	21	+	26627737	RPE1	viability after 12 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.7722593585422368	[695]	[280,359]	5	hSpCas9	negative selection	1227551
31266354	31266377	21	-	26627737	RPE1	viability after 12 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.3749431777778984	[527]	[347,388]	7	hSpCas9	negative selection	1227552
31210111	31210134	21	+	26627737	RPE1	viability after 15 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.12669340318723538	[939]	[103,469]	0	hSpCas9	negative selection	1309862
31217625	31217648	21	-	26627737	RPE1	viability after 15 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.5263436868243682	[994]	[439,371]	3	hSpCas9	negative selection	1309863
31223447	31223470	21	-	26627737	RPE1	viability after 15 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.5982831943578981	[861]	[472,268]	4	hSpCas9	negative selection	1309864
31225866	31225889	21	-	26627737	RPE1	viability after 15 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.09792291998188024	[984]	[342,254]	0	hSpCas9	negative selection	1309865
31252045	31252068	21	+	26627737	RPE1	viability after 15 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.20748037818865078	[695]	[95,353]	1	hSpCas9	negative selection	1309866
31266354	31266377	21	-	26627737	RPE1	viability after 15 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.5695340664194632	[527]	[481,405]	8	hSpCas9	negative selection	1309867
31210111	31210134	21	+	26627737	RPE1	viability after 18 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.2702486484705133	[939]	[274,338]	1	hSpCas9	negative selection	1392177
31217625	31217648	21	-	26627737	RPE1	viability after 18 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.35298095545850894	[994]	[326,359]	2	hSpCas9	negative selection	1392178
31223447	31223470	21	-	26627737	RPE1	viability after 18 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.3396790952828561	[861]	[290,297]	2	hSpCas9	negative selection	1392179
31225866	31225889	21	-	26627737	RPE1	viability after 18 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.4375102400892538	[984]	[189,202]	-3	hSpCas9	negative selection	1392180
31252045	31252068	21	+	26627737	RPE1	viability after 18 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.5952435149072202	[695]	[334,228]	4	hSpCas9	negative selection	1392181
31266354	31266377	21	-	26627737	RPE1	viability after 18 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.2259454936610892	[527]	[341,323]	7	hSpCas9	negative selection	1392182
31210111	31210134	21	+	26627737	HeLa	viability after 8 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.5513508250933346	[532]	[344,294,377]	5	hSpCas9	negative selection	1474492
31217625	31217648	21	-	26627737	HeLa	viability after 8 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.5963230816970326	[752]	[326,138,208]	-5	hSpCas9	negative selection	1474493
31223447	31223470	21	-	26627737	HeLa	viability after 8 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	3.642232456815883	[36]	[381,90,171]	9	hSpCas9	negative selection	1474494
31225866	31225889	21	-	26627737	HeLa	viability after 8 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.07326276469472301	[353]	[194,79,172]	0	hSpCas9	negative selection	1474495
31252045	31252068	21	+	26627737	HeLa	viability after 8 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.047878735859287924	[585]	[232,271,277]	0	hSpCas9	negative selection	1474496
31266354	31266377	21	-	26627737	HeLa	viability after 8 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.407977382327064	[656]	[410,26,248]	-4	hSpCas9	negative selection	1474497
31210111	31210134	21	+	26627737	HeLa	viability after 12 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.3070640531391953	[532]	[346,165,317]	2	hSpCas9	negative selection	1556807
31217625	31217648	21	-	26627737	HeLa	viability after 12 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.42616948656007037	[752]	[459,112,140]	-4	hSpCas9	negative selection	1556808
31223447	31223470	21	-	26627737	HeLa	viability after 12 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	4.182630918874524	[36]	[445,238,156]	9	hSpCas9	negative selection	1556809
31225866	31225889	21	-	26627737	HeLa	viability after 12 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.7654988615845859	[353]	[296,309,133]	6	hSpCas9	negative selection	1556810
31252045	31252068	21	+	26627737	HeLa	viability after 12 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.49784340480425815	[585]	[498,204,340]	4	hSpCas9	negative selection	1556811
31266354	31266377	21	-	26627737	HeLa	viability after 12 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.28709876960357184	[656]	[343,229,430]	2	hSpCas9	negative selection	1556812
31210111	31210134	21	+	26627737	HeLa	viability after 15 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.23927464113671054	[532]	[260,230,277]	2	hSpCas9	negative selection	1639122
31217625	31217648	21	-	26627737	HeLa	viability after 15 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.4543300094024	[752]	[256,138,278]	-4	hSpCas9	negative selection	1639123
31223447	31223470	21	-	26627737	HeLa	viability after 15 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	3.8651107926533808	[36]	[265,182,207]	9	hSpCas9	negative selection	1639124
31225866	31225889	21	-	26627737	HeLa	viability after 15 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.3253188701671472	[353]	[195,170,173]	2	hSpCas9	negative selection	1639125
31252045	31252068	21	+	26627737	HeLa	viability after 15 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.08206259209143174	[585]	[248,166,348]	0	hSpCas9	negative selection	1639126
31266354	31266377	21	-	26627737	HeLa	viability after 15 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.3230418015018157	[656]	[454,323,213]	2	hSpCas9	negative selection	1639127
31210111	31210134	21	+	26627737	HeLa	viability after 18 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.28054620071796227	[532]	[180,201,277]	2	hSpCas9	negative selection	1721437
31217625	31217648	21	-	26627737	HeLa	viability after 18 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.43822674268353773	[752]	[174,117,278]	-4	hSpCas9	negative selection	1721438
31223447	31223470	21	-	26627737	HeLa	viability after 18 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	3.8822408848920924	[36]	[183,150,207]	9	hSpCas9	negative selection	1721439
31225866	31225889	21	-	26627737	HeLa	viability after 18 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.369874216505784	[353]	[138,145,173]	3	hSpCas9	negative selection	1721440
31252045	31252068	21	+	26627737	HeLa	viability after 18 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.07589575165560258	[585]	[165,136,348]	0	hSpCas9	negative selection	1721441
31266354	31266377	21	-	26627737	HeLa	viability after 18 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.394156892456877	[656]	[327,280,213]	3	hSpCas9	negative selection	1721442
31210111	31210134	21	+	26627737	HCT116	viability after 6 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.5761137107921497	[809]	[87,245]	3	hSpCas9	negative selection	1803752
31217625	31217648	21	-	26627737	HCT116	viability after 6 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.9080457591886258	[938]	[247,292]	5	hSpCas9	negative selection	1803753
31223447	31223470	21	-	26627737	HCT116	viability after 6 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	1.088011567632251	[341]	[83,130]	6	hSpCas9	negative selection	1803754
31225866	31225889	21	-	26627737	HCT116	viability after 6 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	3.55066027121772	[78]	[160,136]	9	hSpCas9	negative selection	1803755
31252045	31252068	21	+	26627737	HCT116	viability after 6 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.6457153955778991	[384]	[211,29]	3	hSpCas9	negative selection	1803756
31266354	31266377	21	-	26627737	HCT116	viability after 6 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.39519919132585135	[390]	[9,66]	-2	hSpCas9	negative selection	1803757
31210111	31210134	21	+	26627737	HCT116	viability after 8 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.14045536184754798	[415]	[196,306,252]	1	hSpCas9	negative selection	1886067
31217625	31217648	21	-	26627737	HCT116	viability after 8 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.31918677688883174	[384]	[262,265,264]	3	hSpCas9	negative selection	1886068
31223447	31223470	21	-	26627737	HCT116	viability after 8 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.015695366240587344	[349]	[245,193,133]	0	hSpCas9	negative selection	1886069
31225866	31225889	21	-	26627737	HCT116	viability after 8 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.17086000188431238	[284]	[199,113,105]	-2	hSpCas9	negative selection	1886070
31252045	31252068	21	+	26627737	HCT116	viability after 8 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.18355281982826366	[315]	[165,124,168]	-2	hSpCas9	negative selection	1886071
31266354	31266377	21	-	26627737	HCT116	viability after 8 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.43107491147932364	[371]	[117,143,192]	-5	hSpCas9	negative selection	1886072
31210111	31210134	21	+	26627737	HCT116	viability after 9 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	-0.08576529028710683	[809]	[219,190]	0	hSpCas9	negative selection	1968382
31217625	31217648	21	-	26627737	HCT116	viability after 9 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.5826339638416042	[938]	[315,49]	-4	hSpCas9	negative selection	1968383
31223447	31223470	21	-	26627737	HCT116	viability after 9 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	2.1822558361792073	[341]	[161,613]	9	hSpCas9	negative selection	1968384
31225866	31225889	21	-	26627737	HCT116	viability after 9 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	2.5710428021934195	[78]	[121,127]	9	hSpCas9	negative selection	1968385
31252045	31252068	21	+	26627737	HCT116	viability after 9 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	1.1646443514247329	[384]	[330,150]	7	hSpCas9	negative selection	1968386
31266354	31266377	21	-	26627737	HCT116	viability after 9 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.7286683683546046	[390]	[67,255]	5	hSpCas9	negative selection	1968387
31210111	31210134	21	+	26627737	HCT116	viability after 12 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.513452421071309	[415]	[235,398,309]	5	hSpCas9	negative selection	2050697
31217625	31217648	21	-	26627737	HCT116	viability after 12 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.2722956435911919	[384]	[193,223,318]	3	hSpCas9	negative selection	2050698
31223447	31223470	21	-	26627737	HCT116	viability after 12 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.1805394095266689	[349]	[171,242,72]	-2	hSpCas9	negative selection	2050699
31225866	31225889	21	-	26627737	HCT116	viability after 12 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.3103892433819272	[284]	[136,123,99]	-3	hSpCas9	negative selection	2050700
31252045	31252068	21	+	26627737	HCT116	viability after 12 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.10377679151999067	[315]	[139,199,125]	-1	hSpCas9	negative selection	2050701
31266354	31266377	21	-	26627737	HCT116	viability after 12 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.02458172497472233	[371]	[143,182,273]	0	hSpCas9	negative selection	2050702
31210111	31210134	21	+	26627737	HCT116	viability after 15 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	-0.2182641987079354	[415]	[263,217,141]	-2	hSpCas9	negative selection	2133012
31217625	31217648	21	-	26627737	HCT116	viability after 15 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	-0.06549074622279655	[384]	[208,246,177]	0	hSpCas9	negative selection	2133013
31223447	31223470	21	-	26627737	HCT116	viability after 15 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.27861983739715734	[349]	[394,287,68]	2	hSpCas9	negative selection	2133014
31225866	31225889	21	-	26627737	HCT116	viability after 15 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.3683329784702323	[284]	[187,169,30]	-4	hSpCas9	negative selection	2133015
31252045	31252068	21	+	26627737	HCT116	viability after 15 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.3380305592067252	[315]	[150,168,111]	-4	hSpCas9	negative selection	2133016
31266354	31266377	21	-	26627737	HCT116	viability after 15 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.047215961971689424	[371]	[247,145,230]	0	hSpCas9	negative selection	2133017
31210111	31210134	21	+	26627737	HCT116	viability after 18 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.6332935964834916	[415]	[322,348,258]	5	hSpCas9	negative selection	2215327
31217625	31217648	21	-	26627737	HCT116	viability after 18 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.6177566528326248	[384]	[231,408,203]	5	hSpCas9	negative selection	2215328
31223447	31223470	21	-	26627737	HCT116	viability after 18 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.6203031868051333	[349]	[258,425,75]	5	hSpCas9	negative selection	2215329
31225866	31225889	21	-	26627737	HCT116	viability after 18 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.8959055252249918	[284]	[440,258,59]	7	hSpCas9	negative selection	2215330
31252045	31252068	21	+	26627737	HCT116	viability after 18 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.029597673388828447	[315]	[206,81,184]	0	hSpCas9	negative selection	2215331
31266354	31266377	21	-	26627737	HCT116	viability after 18 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.1835322507049918	[371]	[63,154,260]	-2	hSpCas9	negative selection	2215332
31292387	31292410	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACAGAGTCTTGCTCTGTGG	TIAM1	ENSG00000156299	0.4888228337382956	[6,118]	[1,37]	2	dCas9-VP64	positive selection	2387185
31533225	31533248	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACATGG	TIAM1	ENSG00000156299	6.121120684117956	[31,90]	[7,1976]	9	dCas9-VP64	positive selection	2387439
31340612	31340635	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTCAGCCTCCTGAGTAGCCGG	TIAM1	ENSG00000156299	-0.29935217365489764	[71,81]	[9,16]	-1	dCas9-VP64	positive selection	2389900
31529034	31529057	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTCAGCCTCCCGAGTAGCCGG	TIAM1	ENSG00000156299	0.6074328335071536	[9,93]	[21,11]	2	dCas9-VP64	positive selection	2393285
31181822	31181845	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAATGCAGCAG	TIAM1	ENSG00000156299	-0.2783317302750946	[134,222]	[33,30]	-1	dCas9-VP64	positive selection	2393439
31494065	31494088	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTAGTGG	TIAM1	ENSG00000156299	-0.9180937029961482	[133,53]	[15,3]	-5	dCas9-VP64	positive selection	2405036
31376882	31376905	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTCACTCTGTCACCCGGG	TIAM1	ENSG00000156299	-1.860820956764289	[284,38]	[12,4]	-8	dCas9-VP64	positive selection	2407178
31242456	31242479	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTGCAGTGAGCTGTGATCAG	TIAM1	ENSG00000156299	-0.2191175493670201	[259,121]	[39,30]	-1	dCas9-VP64	positive selection	2412013
31502299	31502322	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCGCCCAGGCAGG	TIAM1	ENSG00000156299	-0.2966468943215429	[82,22]	[4,12]	-1	dCas9-VP64	positive selection	2413501
31487748	31487771	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCTTGTTAGCCAGG	TIAM1	ENSG00000156299	-1.1294869008101784	[149,112]	[16,8]	-6	dCas9-VP64	positive selection	2413727
31283635	31283658	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATTGCTTGAATCCCGG	TIAM1	ENSG00000156299	2.433140723417131	[10,9]	[10,13]	7	dCas9-VP64	positive selection	2414369
31559059	31559082	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGCGGGTTCGAGCGCGGCCGG	TIAM1	ENSG00000156299	0.04044073519779312	[12,18]	[3,1]	0	dCas9-VP64	positive selection	2432236
31559106	31559129	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCCCTCCGCCTGCGGCCTCGG	TIAM1	ENSG00000156299	0.8873190217380809	[148,265]	[102,64]	3	dCas9-VP64	positive selection	2432237
31559084	31559107	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTGCCAATCGGAGCTGTCAGG	TIAM1	ENSG00000156299	-1.0998111575776803	[183,74]	[15,9]	-6	dCas9-VP64	positive selection	2432238
31489366	31489389	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGAGGAGGAGGAGGAGGAGG	TIAM1	ENSG00000156299	1.6116275927184271	[26,1]	[14,2]	6	dCas9-VP64	positive selection	2440191
31522103	31522126	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCGGATCACAAGG	TIAM1	ENSG00000156299	0.6864243628519979	[21,12]	[10,0]	3	dCas9-VP64	positive selection	2442711
31528568	31528591	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCGGATCACATGG	TIAM1	ENSG00000156299	0.6864243628519979	[21,12]	[10,0]	3	dCas9-VP64	positive selection	2442728
31134583	31134606	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCAGG	TIAM1	ENSG00000156299	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444047
31269709	31269732	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCCGGCTGGAGTGCAGTGG	TIAM1	ENSG00000156299	-0.21202295820544315	[11,7]	[0,1]	-1	dCas9-VP64	positive selection	2445440
31467856	31467879	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGGGGATCACGAGGTCAGG	TIAM1	ENSG00000156299	2.4938266432247604	[33,71]	[13,122]	8	dCas9-VP64	positive selection	2450233
31202340	31202363	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCTGGTCTTGAACTCCTGG	TIAM1	ENSG00000156299	1.1112377139242877	[89,193]	[7,132]	4	dCas9-VP64	positive selection	2451726
31540476	31540499	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTATAATCCCGGCACTTTGG	TIAM1	ENSG00000156299	0.25877080368332006	[343,184]	[72,64]	1	dCas9-VP64	positive selection	2453658
31548265	31548288	21	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTGAG	TIAM1	ENSG00000156299	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454590
31384529	31384552	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCACTGCACTCCAGCCCGG	TIAM1	ENSG00000156299	-0.6897978744123147	[436,52]	[50,12]	-4	dCas9-VP64	positive selection	2457789
31552521	31552544	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCGGGG	TIAM1	ENSG00000156299	-0.9342473761319348	[1,66]	[1,4]	-5	dCas9-VP64	positive selection	2466345
31479458	31479481	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATGGATGGATGGATGGAAGG	TIAM1	ENSG00000156299	2.7644531499590617	[51,2]	[77,0]	8	dCas9-VP64	positive selection	2471359
31292387	31292410	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACAGAGTCTTGCTCTGTGG	TIAM1	ENSG00000156299	-0.01585891051551286	[50,117]	[22,29]	0	dCas9-VP64	positive selection	2482440
31533225	31533248	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACATGG	TIAM1	ENSG00000156299	1.1434369151352513	[54,74]	[73,20]	7	dCas9-VP64	positive selection	2482694
31340612	31340635	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTCAGCCTCCTGAGTAGCCGG	TIAM1	ENSG00000156299	0.6576184974956476	[246,231]	[69,172]	5	dCas9-VP64	positive selection	2485155
31529034	31529057	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTCAGCCTCCCGAGTAGCCGG	TIAM1	ENSG00000156299	-0.7211613622673668	[190,191]	[45,29]	-7	dCas9-VP64	positive selection	2488540
31181822	31181845	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAATGCAGCAG	TIAM1	ENSG00000156299	4.153514066093628	[144,313]	[24,2552]	9	dCas9-VP64	positive selection	2488694
31494065	31494088	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTAGTGG	TIAM1	ENSG00000156299	0.01566490298595924	[8,84]	[11,17]	0	dCas9-VP64	positive selection	2500291
31376882	31376905	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTCACTCTGTCACCCGGG	TIAM1	ENSG00000156299	3.0218550163158255	[213,311]	[60,1292]	9	dCas9-VP64	positive selection	2502433
31242456	31242479	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTGCAGTGAGCTGTGATCAG	TIAM1	ENSG00000156299	-0.13774130468097318	[186,55]	[21,49]	-1	dCas9-VP64	positive selection	2507268
31502299	31502322	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCGCCCAGGCAGG	TIAM1	ENSG00000156299	1.7427299536741634	[67,144]	[186,48]	8	dCas9-VP64	positive selection	2508756
31487748	31487771	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCTTGTTAGCCAGG	TIAM1	ENSG00000156299	1.9539419511074274	[45,81]	[33,122]	8	dCas9-VP64	positive selection	2508982
31283635	31283658	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATTGCTTGAATCCCGG	TIAM1	ENSG00000156299	-0.8838793156856553	[97,17]	[18,1]	-8	dCas9-VP64	positive selection	2509624
31559059	31559082	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGCGGGTTCGAGCGCGGCCGG	TIAM1	ENSG00000156299	-1.3940599603187573	[77,36]	[5,6]	-9	dCas9-VP64	positive selection	2527491
31559106	31559129	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCCCTCCGCCTGCGGCCTCGG	TIAM1	ENSG00000156299	1.4329514293318513	[55,130]	[130,34]	7	dCas9-VP64	positive selection	2527492
31559084	31559107	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTGCCAATCGGAGCTGTCAGG	TIAM1	ENSG00000156299	-0.17280016532904222	[154,102]	[20,51]	-2	dCas9-VP64	positive selection	2527493
31489366	31489389	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGAGGAGGAGGAGGAGGAGG	TIAM1	ENSG00000156299	2.5082566135086877	[5,3]	[17,0]	9	dCas9-VP64	positive selection	2535446
31522103	31522126	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCGGATCACAAGG	TIAM1	ENSG00000156299	1.29845831928492	[54,84]	[92,21]	7	dCas9-VP64	positive selection	2537966
31528568	31528591	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCGGATCACATGG	TIAM1	ENSG00000156299	1.29845831928492	[54,84]	[92,21]	7	dCas9-VP64	positive selection	2537983
31134583	31134606	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCAGG	TIAM1	ENSG00000156299	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539302
31269709	31269732	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCCGGCTGGAGTGCAGTGG	TIAM1	ENSG00000156299	1.758955550774001	[111,40]	[35,131]	8	dCas9-VP64	positive selection	2540695
31467856	31467879	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGGGGATCACGAGGTCAGG	TIAM1	ENSG00000156299	1.8499078429495757	[101,144]	[252,43]	8	dCas9-VP64	positive selection	2545488
31202340	31202363	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCTGGTCTTGAACTCCTGG	TIAM1	ENSG00000156299	-0.05379639634842043	[67,143]	[20,43]	0	dCas9-VP64	positive selection	2546981
31540476	31540499	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTATAATCCCGGCACTTTGG	TIAM1	ENSG00000156299	1.162251272123427	[61,207]	[29,161]	7	dCas9-VP64	positive selection	2548913
31548265	31548288	21	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTGAG	TIAM1	ENSG00000156299	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549845
31384529	31384552	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCACTGCACTCCAGCCCGG	TIAM1	ENSG00000156299	0.2274396231328648	[285,212]	[141,51]	1	dCas9-VP64	positive selection	2553044
31552521	31552544	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCGGGG	TIAM1	ENSG00000156299	0.9976288697164769	[174,155]	[180,39]	6	dCas9-VP64	positive selection	2561600
31479458	31479481	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATGGATGGATGGATGGAAGG	TIAM1	ENSG00000156299	-0.745179068402318	[185,151]	[42,22]	-7	dCas9-VP64	positive selection	2566614
31266277	31266300	21	+	27260157	DLD1	viability	CAAGGAATTGGCTCTCTGACAGG	TIAM1	ENSG00000156299	0.614539974968444	[]	[]	8	hSpCas9	negative selection	2574469
31251856	31251879	21	+	27260157	DLD1	viability	TGCCCTGTGCGGCGGTCAGCAGG	TIAM1	ENSG00000156299	0.555914683217007	[]	[]	8	hSpCas9	negative selection	2577628
31252067	31252090	21	+	27260157	DLD1	viability	GCCTGTGGTGGGTGAGTAGCTGG	TIAM1	ENSG00000156299	0.401912078587519	[]	[]	4	hSpCas9	negative selection	2577752
31266310	31266333	21	-	27260157	DLD1	viability	TGGAAACGCGGGCGAGTCCGCGG	TIAM1	ENSG00000156299	-0.219020753135446	[]	[]	-2	hSpCas9	negative selection	2578783
31266858	31266881	21	+	27260157	DLD1	viability	TCCTCCGCGTCTTGTGCGAGAGG	TIAM1	ENSG00000156299	-0.609211278942246	[]	[]	-5	hSpCas9	negative selection	2581344
31266206	31266229	21	+	27260157	DLD1	viability	TAGCCTGCAAATTTGCTCCCCGG	TIAM1	ENSG00000156299	-0.0266539080474897	[]	[]	0	hSpCas9	negative selection	2604931
31252040	31252063	21	+	27260157	DLD1	viability	GCCGCTGTCGCTGCCCACAAAGG	TIAM1	ENSG00000156299	-0.363064455030964	[]	[]	-3	hSpCas9	negative selection	2606305
31266345	31266368	21	-	27260157	DLD1	viability	CGCCGAAGAGAAGGACTGCGAGG	TIAM1	ENSG00000156299	0.800459696047075	[]	[]	9	hSpCas9	negative selection	2607518
31252091	31252114	21	+	27260157	DLD1	viability	GTTGGTGGCATTAGATCGCCTGG	TIAM1	ENSG00000156299	-0.764033157297097	[]	[]	-5	hSpCas9	negative selection	2609237
31266192	31266215	21	-	27260157	DLD1	viability	TGCAGGCTACTGTCGGAATTTGG	TIAM1	ENSG00000156299	-0.418317412199511	[]	[]	-3	hSpCas9	negative selection	2616220
31266622	31266645	21	+	27260157	DLD1	viability	GACGATGCTGCTGTCTACGCTGG	TIAM1	ENSG00000156299	-0.219761925976237	[]	[]	-2	hSpCas9	negative selection	2619148
31251883	31251906	21	-	27260157	DLD1	viability	CCTGAGCTCTCCGGGCCAGTCGG	TIAM1	ENSG00000156299	0.759654465478207	[]	[]	8	hSpCas9	negative selection	2620255
31252053	31252076	21	-	27260157	DLD1	viability	ACCACAGGCCGGGCCTTTGTGGG	TIAM1	ENSG00000156299	-0.226751922367859	[]	[]	-2	hSpCas9	negative selection	2622645
31266853	31266876	21	-	27260157	DLD1	viability	CGCACAAGACGCGGAGGACCAGG	TIAM1	ENSG00000156299	0.594711797653348	[]	[]	8	hSpCas9	negative selection	2622653
31251920	31251943	21	+	27260157	DLD1	viability	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	0.0287640350878587	[]	[]	0	hSpCas9	negative selection	2641217
31266952	31266975	21	+	27260157	DLD1	viability	TTGACTTTCTGCGTTTCCCATGG	TIAM1	ENSG00000156299	0.618628006101301	[]	[]	8	hSpCas9	negative selection	2642474
31266734	31266757	21	-	27260157	DLD1	viability	CTGGAGCCCTTCTCCCAAGATGG	TIAM1	ENSG00000156299	1.25989769360946	[]	[]	9	hSpCas9	negative selection	2647584
31251868	31251891	21	+	27260157	DLD1	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.277097613846238	[]	[]	4	hSpCas9	negative selection	2647740
31266442	31266465	21	+	27260157	DLD1	viability	CCGCCAGATGTCTGCAGATTTGG	TIAM1	ENSG00000156299	0.917855757560649	[]	[]	9	hSpCas9	negative selection	2647742
31266277	31266300	21	+	27260157	HT1080	viability	CAAGGAATTGGCTCTCTGACAGG	TIAM1	ENSG00000156299	0.256085059537431	[]	[]	2	hSpCas9	negative selection	2650599
31251856	31251879	21	+	27260157	HT1080	viability	TGCCCTGTGCGGCGGTCAGCAGG	TIAM1	ENSG00000156299	1.38150321615372	[]	[]	9	hSpCas9	negative selection	2653758
31252067	31252090	21	+	27260157	HT1080	viability	GCCTGTGGTGGGTGAGTAGCTGG	TIAM1	ENSG00000156299	0.241490601875562	[]	[]	2	hSpCas9	negative selection	2653882
31266310	31266333	21	-	27260157	HT1080	viability	TGGAAACGCGGGCGAGTCCGCGG	TIAM1	ENSG00000156299	0.492719503292122	[]	[]	4	hSpCas9	negative selection	2654913
31266858	31266881	21	+	27260157	HT1080	viability	TCCTCCGCGTCTTGTGCGAGAGG	TIAM1	ENSG00000156299	0.57442062926833	[]	[]	5	hSpCas9	negative selection	2657474
31266206	31266229	21	+	27260157	HT1080	viability	TAGCCTGCAAATTTGCTCCCCGG	TIAM1	ENSG00000156299	-0.157571971827803	[]	[]	0	hSpCas9	negative selection	2681061
31252040	31252063	21	+	27260157	HT1080	viability	GCCGCTGTCGCTGCCCACAAAGG	TIAM1	ENSG00000156299	-0.185804225133393	[]	[]	0	hSpCas9	negative selection	2682435
31266345	31266368	21	-	27260157	HT1080	viability	CGCCGAAGAGAAGGACTGCGAGG	TIAM1	ENSG00000156299	1.1222144832165	[]	[]	8	hSpCas9	negative selection	2683648
31252091	31252114	21	+	27260157	HT1080	viability	GTTGGTGGCATTAGATCGCCTGG	TIAM1	ENSG00000156299	-0.573228161155608	[]	[]	-7	hSpCas9	negative selection	2685367
31266192	31266215	21	-	27260157	HT1080	viability	TGCAGGCTACTGTCGGAATTTGG	TIAM1	ENSG00000156299	1.31987734014664	[]	[]	9	hSpCas9	negative selection	2692350
31266622	31266645	21	+	27260157	HT1080	viability	GACGATGCTGCTGTCTACGCTGG	TIAM1	ENSG00000156299	1.62203212003838	[]	[]	9	hSpCas9	negative selection	2695278
31251883	31251906	21	-	27260157	HT1080	viability	CCTGAGCTCTCCGGGCCAGTCGG	TIAM1	ENSG00000156299	-0.464033412064392	[]	[]	-7	hSpCas9	negative selection	2696385
31252053	31252076	21	-	27260157	HT1080	viability	ACCACAGGCCGGGCCTTTGTGGG	TIAM1	ENSG00000156299	0.0317248717477686	[]	[]	0	hSpCas9	negative selection	2698775
31266853	31266876	21	-	27260157	HT1080	viability	CGCACAAGACGCGGAGGACCAGG	TIAM1	ENSG00000156299	0.115041687707407	[]	[]	1	hSpCas9	negative selection	2698783
31251920	31251943	21	+	27260157	HT1080	viability	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	0.0944256717079128	[]	[]	1	hSpCas9	negative selection	2717347
31266952	31266975	21	+	27260157	HT1080	viability	TTGACTTTCTGCGTTTCCCATGG	TIAM1	ENSG00000156299	0.2181895980155	[]	[]	2	hSpCas9	negative selection	2718604
31266734	31266757	21	-	27260157	HT1080	viability	CTGGAGCCCTTCTCCCAAGATGG	TIAM1	ENSG00000156299	0.995125079541354	[]	[]	8	hSpCas9	negative selection	2723714
31251868	31251891	21	+	27260157	HT1080	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.992744503339792	[]	[]	8	hSpCas9	negative selection	2723870
31266442	31266465	21	+	27260157	HT1080	viability	CCGCCAGATGTCTGCAGATTTGG	TIAM1	ENSG00000156299	-0.0637547987395589	[]	[]	0	hSpCas9	negative selection	2723872
31266277	31266300	21	+	27260157	MKN45	viability	CAAGGAATTGGCTCTCTGACAGG	TIAM1	ENSG00000156299	0.16674408683344	[]	[]	5	hSpCas9	negative selection	2726729
31251856	31251879	21	+	27260157	MKN45	viability	TGCCCTGTGCGGCGGTCAGCAGG	TIAM1	ENSG00000156299	-0.0145789422688329	[]	[]	0	hSpCas9	negative selection	2729888
31252067	31252090	21	+	27260157	MKN45	viability	GCCTGTGGTGGGTGAGTAGCTGG	TIAM1	ENSG00000156299	0.960939782549319	[]	[]	8	hSpCas9	negative selection	2730012
31266310	31266333	21	-	27260157	MKN45	viability	TGGAAACGCGGGCGAGTCCGCGG	TIAM1	ENSG00000156299	0.904770886082991	[]	[]	8	hSpCas9	negative selection	2731043
31266858	31266881	21	+	27260157	MKN45	viability	TCCTCCGCGTCTTGTGCGAGAGG	TIAM1	ENSG00000156299	0.321702029339038	[]	[]	5	hSpCas9	negative selection	2733604
31266206	31266229	21	+	27260157	MKN45	viability	TAGCCTGCAAATTTGCTCCCCGG	TIAM1	ENSG00000156299	-0.201177101518618	[]	[]	0	hSpCas9	negative selection	2757191
31252040	31252063	21	+	27260157	MKN45	viability	GCCGCTGTCGCTGCCCACAAAGG	TIAM1	ENSG00000156299	0.16597807975188	[]	[]	5	hSpCas9	negative selection	2758565
31266345	31266368	21	-	27260157	MKN45	viability	CGCCGAAGAGAAGGACTGCGAGG	TIAM1	ENSG00000156299	1.29633810114014	[]	[]	9	hSpCas9	negative selection	2759778
31252091	31252114	21	+	27260157	MKN45	viability	GTTGGTGGCATTAGATCGCCTGG	TIAM1	ENSG00000156299	-1.7448024834201	[]	[]	-9	hSpCas9	negative selection	2761497
31266192	31266215	21	-	27260157	MKN45	viability	TGCAGGCTACTGTCGGAATTTGG	TIAM1	ENSG00000156299	0.828538280606811	[]	[]	8	hSpCas9	negative selection	2768480
31266622	31266645	21	+	27260157	MKN45	viability	GACGATGCTGCTGTCTACGCTGG	TIAM1	ENSG00000156299	2.05357760117726	[]	[]	9	hSpCas9	negative selection	2771408
31251883	31251906	21	-	27260157	MKN45	viability	CCTGAGCTCTCCGGGCCAGTCGG	TIAM1	ENSG00000156299	0.570358204018815	[]	[]	7	hSpCas9	negative selection	2772515
31252053	31252076	21	-	27260157	MKN45	viability	ACCACAGGCCGGGCCTTTGTGGG	TIAM1	ENSG00000156299	-0.603369444930109	[]	[]	-6	hSpCas9	negative selection	2774905
31266853	31266876	21	-	27260157	MKN45	viability	CGCACAAGACGCGGAGGACCAGG	TIAM1	ENSG00000156299	0.0210877191092547	[]	[]	0	hSpCas9	negative selection	2774913
31251920	31251943	21	+	27260157	MKN45	viability	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	-0.617935141885768	[]	[]	-6	hSpCas9	negative selection	2793477
31266952	31266975	21	+	27260157	MKN45	viability	TTGACTTTCTGCGTTTCCCATGG	TIAM1	ENSG00000156299	0.335472991304223	[]	[]	6	hSpCas9	negative selection	2794734
31266734	31266757	21	-	27260157	MKN45	viability	CTGGAGCCCTTCTCCCAAGATGG	TIAM1	ENSG00000156299	1.21037707094552	[]	[]	9	hSpCas9	negative selection	2799844
31251868	31251891	21	+	27260157	MKN45	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	1.50108888872428	[]	[]	9	hSpCas9	negative selection	2800000
31266442	31266465	21	+	27260157	MKN45	viability	CCGCCAGATGTCTGCAGATTTGG	TIAM1	ENSG00000156299	1.35349224903374	[]	[]	9	hSpCas9	negative selection	2800002
31266277	31266300	21	+	27260157	RKO	viability	CAAGGAATTGGCTCTCTGACAGG	TIAM1	ENSG00000156299	0.553914894680225	[]	[]	3	hSpCas9	negative selection	2802859
31251856	31251879	21	+	27260157	RKO	viability	TGCCCTGTGCGGCGGTCAGCAGG	TIAM1	ENSG00000156299	1.01309231396201	[]	[]	9	hSpCas9	negative selection	2806018
31252067	31252090	21	+	27260157	RKO	viability	GCCTGTGGTGGGTGAGTAGCTGG	TIAM1	ENSG00000156299	0.843213896428274	[]	[]	8	hSpCas9	negative selection	2806142
31266310	31266333	21	-	27260157	RKO	viability	TGGAAACGCGGGCGAGTCCGCGG	TIAM1	ENSG00000156299	0.676833526507708	[]	[]	7	hSpCas9	negative selection	2807173
31266858	31266881	21	+	27260157	RKO	viability	TCCTCCGCGTCTTGTGCGAGAGG	TIAM1	ENSG00000156299	0.231291246009163	[]	[]	1	hSpCas9	negative selection	2809734
31266206	31266229	21	+	27260157	RKO	viability	TAGCCTGCAAATTTGCTCCCCGG	TIAM1	ENSG00000156299	0.286117513315982	[]	[]	1	hSpCas9	negative selection	2833321
31252040	31252063	21	+	27260157	RKO	viability	GCCGCTGTCGCTGCCCACAAAGG	TIAM1	ENSG00000156299	0.841714234220913	[]	[]	8	hSpCas9	negative selection	2834695
31266345	31266368	21	-	27260157	RKO	viability	CGCCGAAGAGAAGGACTGCGAGG	TIAM1	ENSG00000156299	0.880493357087325	[]	[]	8	hSpCas9	negative selection	2835908
31252091	31252114	21	+	27260157	RKO	viability	GTTGGTGGCATTAGATCGCCTGG	TIAM1	ENSG00000156299	0.23004414535005	[]	[]	1	hSpCas9	negative selection	2837627
31266192	31266215	21	-	27260157	RKO	viability	TGCAGGCTACTGTCGGAATTTGG	TIAM1	ENSG00000156299	0.552527984068106	[]	[]	3	hSpCas9	negative selection	2844610
31266622	31266645	21	+	27260157	RKO	viability	GACGATGCTGCTGTCTACGCTGG	TIAM1	ENSG00000156299	1.70892060422272	[]	[]	9	hSpCas9	negative selection	2847538
31251883	31251906	21	-	27260157	RKO	viability	CCTGAGCTCTCCGGGCCAGTCGG	TIAM1	ENSG00000156299	0.119633230433263	[]	[]	0	hSpCas9	negative selection	2848645
31252053	31252076	21	-	27260157	RKO	viability	ACCACAGGCCGGGCCTTTGTGGG	TIAM1	ENSG00000156299	0.561140399582758	[]	[]	3	hSpCas9	negative selection	2851035
31266853	31266876	21	-	27260157	RKO	viability	CGCACAAGACGCGGAGGACCAGG	TIAM1	ENSG00000156299	0.504407099455302	[]	[]	2	hSpCas9	negative selection	2851043
31251920	31251943	21	+	27260157	RKO	viability	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	-0.41675732552566	[]	[]	-6	hSpCas9	negative selection	2869607
31266952	31266975	21	+	27260157	RKO	viability	TTGACTTTCTGCGTTTCCCATGG	TIAM1	ENSG00000156299	0.789578912795366	[]	[]	8	hSpCas9	negative selection	2870864
31266734	31266757	21	-	27260157	RKO	viability	CTGGAGCCCTTCTCCCAAGATGG	TIAM1	ENSG00000156299	0.999306477039168	[]	[]	9	hSpCas9	negative selection	2875974
31251868	31251891	21	+	27260157	RKO	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	1.42608039317205	[]	[]	9	hSpCas9	negative selection	2876130
31266442	31266465	21	+	27260157	RKO	viability	CCGCCAGATGTCTGCAGATTTGG	TIAM1	ENSG00000156299	0.569619517706814	[]	[]	3	hSpCas9	negative selection	2876132
31266277	31266300	21	+	27260157	SF268	viability	CAAGGAATTGGCTCTCTGACAGG	TIAM1	ENSG00000156299	-0.314496653397121	[]	[]	-2	hSpCas9	negative selection	2878989
31251856	31251879	21	+	27260157	SF268	viability	TGCCCTGTGCGGCGGTCAGCAGG	TIAM1	ENSG00000156299	0.680591977576863	[]	[]	8	hSpCas9	negative selection	2882148
31252067	31252090	21	+	27260157	SF268	viability	GCCTGTGGTGGGTGAGTAGCTGG	TIAM1	ENSG00000156299	0.208325226204567	[]	[]	3	hSpCas9	negative selection	2882272
31266310	31266333	21	-	27260157	SF268	viability	TGGAAACGCGGGCGAGTCCGCGG	TIAM1	ENSG00000156299	0.222025998660037	[]	[]	3	hSpCas9	negative selection	2883303
31266858	31266881	21	+	27260157	SF268	viability	TCCTCCGCGTCTTGTGCGAGAGG	TIAM1	ENSG00000156299	0.254390687276236	[]	[]	4	hSpCas9	negative selection	2885864
31266206	31266229	21	+	27260157	SF268	viability	TAGCCTGCAAATTTGCTCCCCGG	TIAM1	ENSG00000156299	0.23123854934633	[]	[]	3	hSpCas9	negative selection	2909451
31252040	31252063	21	+	27260157	SF268	viability	GCCGCTGTCGCTGCCCACAAAGG	TIAM1	ENSG00000156299	0.827709579292893	[]	[]	8	hSpCas9	negative selection	2910825
31266345	31266368	21	-	27260157	SF268	viability	CGCCGAAGAGAAGGACTGCGAGG	TIAM1	ENSG00000156299	0.909788256740311	[]	[]	9	hSpCas9	negative selection	2912038
31252091	31252114	21	+	27260157	SF268	viability	GTTGGTGGCATTAGATCGCCTGG	TIAM1	ENSG00000156299	-0.243273222087064	[]	[]	-2	hSpCas9	negative selection	2913757
31266192	31266215	21	-	27260157	SF268	viability	TGCAGGCTACTGTCGGAATTTGG	TIAM1	ENSG00000156299	0.291119320018874	[]	[]	4	hSpCas9	negative selection	2920740
31266622	31266645	21	+	27260157	SF268	viability	GACGATGCTGCTGTCTACGCTGG	TIAM1	ENSG00000156299	1.15710921737321	[]	[]	9	hSpCas9	negative selection	2923668
31251883	31251906	21	-	27260157	SF268	viability	CCTGAGCTCTCCGGGCCAGTCGG	TIAM1	ENSG00000156299	0.665227792217379	[]	[]	8	hSpCas9	negative selection	2924775
31252053	31252076	21	-	27260157	SF268	viability	ACCACAGGCCGGGCCTTTGTGGG	TIAM1	ENSG00000156299	-0.554713451442572	[]	[]	-4	hSpCas9	negative selection	2927165
31266853	31266876	21	-	27260157	SF268	viability	CGCACAAGACGCGGAGGACCAGG	TIAM1	ENSG00000156299	-0.0990973536678962	[]	[]	-1	hSpCas9	negative selection	2927173
31251920	31251943	21	+	27260157	SF268	viability	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	-1.22435210250865	[]	[]	-7	hSpCas9	negative selection	2945737
31266952	31266975	21	+	27260157	SF268	viability	TTGACTTTCTGCGTTTCCCATGG	TIAM1	ENSG00000156299	-0.171092838722909	[]	[]	-1	hSpCas9	negative selection	2946994
31266734	31266757	21	-	27260157	SF268	viability	CTGGAGCCCTTCTCCCAAGATGG	TIAM1	ENSG00000156299	0.964005114142295	[]	[]	9	hSpCas9	negative selection	2952104
31251868	31251891	21	+	27260157	SF268	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	1.20074349537007	[]	[]	9	hSpCas9	negative selection	2952260
31266442	31266465	21	+	27260157	SF268	viability	CCGCCAGATGTCTGCAGATTTGG	TIAM1	ENSG00000156299	0.641347159058975	[]	[]	8	hSpCas9	negative selection	2952262
31266824	31266847	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.3728473826926987	[3,3]	[2,1]	-5	hSpCas9	positive selection	3026754
31266838	31266861	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	0.28534857167017874	[3,3]	[4,3]	6	hSpCas9	positive selection	3026755
31225935	31225958	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	-0.19872124247684764	[3,3]	[2,1]	-3	hSpCas9	positive selection	3026756
31251985	31252008	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.6708258955574892	[3,3]	[2,0]	-7	hSpCas9	positive selection	3026757
31266824	31266847	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.487358051340658	[3,3]	[3,0]	-7	hSpCas9	positive selection	3094612
31266838	31266861	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	-0.17527082342280673	[3,3]	[3,1]	-3	hSpCas9	positive selection	3094613
31225935	31225958	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	0.3804515848770674	[3,3]	[3,2]	6	hSpCas9	positive selection	3094614
31251985	31252008	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.616724051957326	[3,3]	[3,3]	8	hSpCas9	positive selection	3094615
31252115	31252138		+	24336571	A375	resistance to PLX after 7 days	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	0.3830933220168263	[11,11]	[13,16]	8	hSpCas9	positive selection	3150255
31245630	31245653		-	24336571	A375	resistance to PLX after 7 days	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	0.018853549308061934	[3,3]	[4,3]	0	hSpCas9	positive selection	3150256
31251920	31251943		+	24336571	A375	resistance to PLX after 7 days	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	0.33805492944536786	[3,3]	[4,4]	8	hSpCas9	positive selection	3150259
31245584	31245607		-	24336571	A375	resistance to PLX after 7 days	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	-0.020901851241632685	[8,8]	[9,7]	0	hSpCas9	positive selection	3150260
31252115	31252138		+	24336571	A375	resistance to PLX after 14 days	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	0.6487591320895107	[9,9]	[6,7]	6	hSpCas9	positive selection	3208048
31245630	31245653		-	24336571	A375	resistance to PLX after 14 days	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	0.5855259450990955	[2,1]	[1,1]	5	hSpCas9	positive selection	3208049
31251920	31251943		+	24336571	A375	resistance to PLX after 14 days	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	1.3432919168223187	[3,4]	[4,4]	8	hSpCas9	positive selection	3208052
31245584	31245607		-	24336571	A375	resistance to PLX after 14 days	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.5062416116450383	[6,6]	[3,4]	5	hSpCas9	positive selection	3208053
31252115	31252138		+	24336571	A375	viability after 7 days	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	-0.18709220665354367	[13]	[11,11]	-3	hSpCas9	negative selection	3265841
31245630	31245653		-	24336571	A375	viability after 7 days	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	-0.4328317841917224	[5]	[3,3]	-6	hSpCas9	negative selection	3265842
31251920	31251943		+	24336571	A375	viability after 7 days	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	-0.14972487912299104	[4]	[3,3]	-2	hSpCas9	negative selection	3265845
31245584	31245607		-	24336571	A375	viability after 7 days	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.3941607524266487	[6]	[8,8]	6	hSpCas9	negative selection	3265846
31252115	31252138		+	24336571	A375	viability after 14 days	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	-0.35727277340711483	[13]	[9,9]	-4	hSpCas9	negative selection	3323634
31245630	31245653		-	24336571	A375	viability after 14 days	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	-0.977984168752515	[5]	[2,1]	-8	hSpCas9	negative selection	3323635
31251920	31251943		+	24336571	A375	viability after 14 days	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	-0.057672272188069584	[4]	[3,4]	0	hSpCas9	negative selection	3323638
31245584	31245607		-	24336571	A375	viability after 14 days	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.1175287800817506	[6]	[6,6]	1	hSpCas9	negative selection	3323639
31225879	31225902	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.7337642553888224	[91,91]	[0,0]	3	hSpCas9	positive selection	3397157
31225851	31225874	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.600654783681737	[231,231]	[0,0]	-4	hSpCas9	positive selection	3397158
31245592	31245615	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3397159
31266823	31266846	21	+	26780180	HT29	viability (Avana library 4 designs)	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.810231259398888	[]	[]	3	hSpCas9	negative selection	3465495
31266838	31266861	21	-	26780180	HT29	viability (Avana library 4 designs)	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	1.53928833663137	[]	[]	6	hSpCas9	negative selection	3465496
31225935	31225958	21	-	26780180	HT29	viability (Avana library 4 designs)	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	1.09693237136714	[]	[]	4	hSpCas9	negative selection	3465497
31251985	31252008	21	-	26780180	HT29	viability (Avana library 4 designs)	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.307032189323426	[]	[]	1	hSpCas9	negative selection	3465498
31251985	31252008	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.148654275031119	[]	[]	0	hSpCas9	negative selection	3568715
31225935	31225958	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	0.0417358047345491	[]	[]	0	hSpCas9	negative selection	3568716
31266823	31266846	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.292418813189115	[]	[]	0	hSpCas9	negative selection	3568717
31266838	31266861	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	2.52830287812577	[]	[]	4	hSpCas9	negative selection	3568718
31223423	31223446	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCGAAAAGATTCCAAGGCGG	TIAM1	ENSG00000156299	-1.56721157349509	[]	[]	-2	hSpCas9	negative selection	3568719
31251909	31251932	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACAGCGATGAGCAGAGCAGCGG	TIAM1	ENSG00000156299	4.5896156038075	[]	[]	7	hSpCas9	negative selection	3568720
31251985	31252008	21	-	26780180	A375	viability (Avana lentiGuide)	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-1.9923062193527	[]	[]	-3	hSpCas9	negative selection	3677374
31225935	31225958	21	-	26780180	A375	viability (Avana lentiGuide)	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	0.396836367876551	[]	[]	0	hSpCas9	negative selection	3677375
31266823	31266846	21	+	26780180	A375	viability (Avana lentiGuide)	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.422803550627652	[]	[]	0	hSpCas9	negative selection	3677376
31266838	31266861	21	-	26780180	A375	viability (Avana lentiGuide)	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	-1.26203887323217	[]	[]	-2	hSpCas9	negative selection	3677377
31223423	31223446	21	+	26780180	A375	viability (Avana lentiGuide)	ATACCGAAAAGATTCCAAGGCGG	TIAM1	ENSG00000156299	4.47977728170432	[]	[]	4	hSpCas9	negative selection	3677378
31251909	31251932	21	-	26780180	A375	viability (Avana lentiGuide)	CACAGCGATGAGCAGAGCAGCGG	TIAM1	ENSG00000156299	5.77175746577371	[]	[]	5	hSpCas9	negative selection	3677379
31251985	31252008	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.008508653022222784	[4]	[3,4]	0	hSpCas9	positive selection	3785981
31225935	31225958	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	-0.47266543554511825	[4]	[2,2]	-6	hSpCas9	positive selection	3785982
31266823	31266846	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.17866146342828473	[4]	[5,2]	-3	hSpCas9	positive selection	3785983
31266838	31266861	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	0.16591322701289632	[5]	[6,5]	4	hSpCas9	positive selection	3785984
31223423	31223446	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCGAAAAGATTCCAAGGCGG	TIAM1	ENSG00000156299	-0.08440282317385853	[6]	[5,5]	-1	hSpCas9	positive selection	3785985
31251909	31251932	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACAGCGATGAGCAGAGCAGCGG	TIAM1	ENSG00000156299	0.3066887630898094	[4]	[5,4]	8	hSpCas9	positive selection	3785986
31251985	31252008	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.23122275338731754	[5]	[5,5]	6	hSpCas9	positive selection	3894588
31225935	31225958	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTACAGACCACTAGCCAGACGG	TIAM1	ENSG00000156299	-0.11488279014229096	[5]	[4,3]	-2	hSpCas9	positive selection	3894589
31266823	31266846	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.12171436823596782	[5]	[5,2]	-2	hSpCas9	positive selection	3894590
31266838	31266861	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCAGGCACGCTTCCTCGGGG	TIAM1	ENSG00000156299	0.3067353134580355	[6]	[6,6]	8	hSpCas9	positive selection	3894591
31223423	31223446	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCGAAAAGATTCCAAGGCGG	TIAM1	ENSG00000156299	0.1330644048066028	[6]	[6,5]	3	hSpCas9	positive selection	3894592
31251909	31251932	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACAGCGATGAGCAGAGCAGCGG	TIAM1	ENSG00000156299	-0.8386349031072502	[3]	[1,0]	-8	hSpCas9	positive selection	3894593
31225879	31225902	21	+	26780180	A375	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.787515118624627	[]	[]	3	hSpCas9	negative selection	4003944
31251868	31251891	21	+	26780180	A375	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	1.13440571118684	[]	[]	6	hSpCas9	negative selection	4003945
31245592	31245615	21	+	26780180	A375	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.507458097719675	[]	[]	1	hSpCas9	negative selection	4003946
31245584	31245607	21	-	26780180	A375	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.14997797318674	[]	[]	6	hSpCas9	negative selection	4003947
31225851	31225874	21	+	26780180	A375	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	1.12423708123653	[]	[]	5	hSpCas9	negative selection	4003948
31252123	31252146	21	-	26780180	A375	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	1.3038843112556	[]	[]	7	hSpCas9	negative selection	4003949
31225879	31225902	21	+	26780180	HT29	viability (GeCKOv2 library)	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.952228291767047	[]	[]	4	hSpCas9	negative selection	4111910
31251868	31251891	21	+	26780180	HT29	viability (GeCKOv2 library)	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.56323177046897	[]	[]	2	hSpCas9	negative selection	4111911
31245592	31245615	21	+	26780180	HT29	viability (GeCKOv2 library)	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.710278996815142	[]	[]	2	hSpCas9	negative selection	4111912
31245584	31245607	21	-	26780180	HT29	viability (GeCKOv2 library)	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.484777409935	[]	[]	7	hSpCas9	negative selection	4111913
31225851	31225874	21	+	26780180	HT29	viability (GeCKOv2 library)	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	1.00503069373545	[]	[]	4	hSpCas9	negative selection	4111914
31252123	31252146	21	-	26780180	HT29	viability (GeCKOv2 library)	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	1.25443116113489	[]	[]	6	hSpCas9	negative selection	4111915
31252115	31252138	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	0.03338630941773452	[3]	[2,2]	0	hSpCas9	positive selection	4176647
31245630	31245653	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	-0.7405180662363873	[2]	[0,0]	-9	hSpCas9	positive selection	4176648
31251920	31251943	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	0.5679019694981418	[1]	[1,2]	9	hSpCas9	positive selection	4176651
31245584	31245607	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.3829186534210783	[2]	[1,2]	8	hSpCas9	positive selection	4176652
31252115	31252138	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGAGGTCCGTGTCGGTAGTGG	TIAM1	ENSG00000156299	-0.28751645074836585	[3]	[0,0,2,0]	-4	hSpCas9	positive selection	4240669
31245630	31245653	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTATTTTTCTACGAGAGCGACGG	TIAM1	ENSG00000156299	0.027715531956011508	[2]	[0,0,3,0]	0	hSpCas9	positive selection	4240670
31251920	31251943	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCATCGCTGTGCGCCGAGCCGG	TIAM1	ENSG00000156299	0.3769115693613158	[1]	[2,0,0,0]	3	hSpCas9	positive selection	4240673
31245584	31245607	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	-0.4131458211924151	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4240674
31245584	31245607	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.049826206000292	[3]	[3,2]	1	hSpCas9	positive selection	4303060
31252123	31252146	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.35293804477239055	[2]	[2,2]	7	hSpCas9	positive selection	4303061
31251868	31251891	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.07291736613079272	[2]	[2,1]	1	hSpCas9	positive selection	4303062
31462546	31462569	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.6602045597716526	[2]	[0,0]	-9	hSpCas9	positive selection	4315548
31225879	31225902	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.23537161247274024	[2]	[2,1]	5	hSpCas9	positive selection	4367313
31225851	31225874	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.25599978296640097	[3]	[3,2]	5	hSpCas9	positive selection	4367314
31245592	31245615	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.12074542622166011	[3]	[3,1]	2	hSpCas9	positive selection	4367315
31210082	31210104	21	+	27760321	OCIAML3	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.23337267950323848	[1141,959]	[791,1184]	2	hSpCas9	negative selection	4446919
31217626	31217648	21	+	27760321	OCIAML3	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	0.1405116010021038	[668,865]	[652,693]	1	hSpCas9	negative selection	4446920
31225874	31225896	21	+	27760321	OCIAML3	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.6233286790786341	[380,398]	[218,172]	-6	hSpCas9	negative selection	4446921
31251986	31252008	21	-	27760321	OCIAML3	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.25045654814698026	[513,481]	[358,599]	3	hSpCas9	negative selection	4446922
31252097	31252119	21	+	27760321	OCIAML3	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.02842216072038828	[679,565]	[361,667]	0	hSpCas9	negative selection	4446923
31210082	31210104	21	+	27760321	OCIAML2	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.6901762967060996	[1141,959]	[1158,1639]	8	hSpCas9	negative selection	4530382
31217626	31217648	21	+	27760321	OCIAML2	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	0.33687284034553433	[668,865]	[750,852]	4	hSpCas9	negative selection	4530383
31225874	31225896	21	+	27760321	OCIAML2	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	0.35605485651003205	[380,398]	[357,468]	5	hSpCas9	negative selection	4530384
31251986	31252008	21	-	27760321	OCIAML2	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	-0.44193035648426326	[513,481]	[310,277]	-5	hSpCas9	negative selection	4530385
31252097	31252119	21	+	27760321	OCIAML2	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.0757514594084836	[679,565]	[458,620]	1	hSpCas9	negative selection	4530386
31210082	31210104	21	+	27760321	MV411	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.19153363118791278	[1141,959]	[543,1156]	1	hSpCas9	negative selection	4613845
31217626	31217648	21	+	27760321	MV411	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	0.6450790077615138	[668,865]	[780,835]	5	hSpCas9	negative selection	4613846
31225874	31225896	21	+	27760321	MV411	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	1.3556673145971916	[380,398]	[707,592]	8	hSpCas9	negative selection	4613847
31251986	31252008	21	-	27760321	MV411	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	-0.6446654622523345	[513,481]	[139,315]	-4	hSpCas9	negative selection	4613848
31252097	31252119	21	+	27760321	MV411	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	-0.5478798135338395	[679,565]	[311,231]	-4	hSpCas9	negative selection	4613849
31210082	31210104	21	+	27760321	HL60	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.4534319622982397	[1141,959]	[875,1483]	5	hSpCas9	negative selection	4697308
31217626	31217648	21	+	27760321	HL60	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.08138608764030109	[668,865]	[459,749]	-1	hSpCas9	negative selection	4697309
31225874	31225896	21	+	27760321	HL60	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	0.19231408251890594	[380,398]	[378,351]	2	hSpCas9	negative selection	4697310
31251986	31252008	21	-	27760321	HL60	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.33383001870265705	[513,481]	[464,563]	4	hSpCas9	negative selection	4697311
31252097	31252119	21	+	27760321	HL60	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.08149373155504414	[679,565]	[476,598]	1	hSpCas9	negative selection	4697312
31210082	31210104	21	+	27760321	HT1080	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.830249183501905	[959,748]	[725,472]	4	hSpCas9	negative selection	4780771
31217626	31217648	21	+	27760321	HT1080	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.18487202978232764	[865,675]	[263,276]	-1	hSpCas9	negative selection	4780772
31225874	31225896	21	+	27760321	HT1080	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.06980221946746368	[398,311]	[175,89]	0	hSpCas9	negative selection	4780773
31251986	31252008	21	-	27760321	HT1080	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.5944878087062271	[481,375]	[279,233]	3	hSpCas9	negative selection	4780774
31252097	31252119	21	+	27760321	HT1080	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.5884902671689913	[565,441]	[257,349]	3	hSpCas9	negative selection	4780775
31210082	31210104	21	+	27760321	HT29	viability after 7 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.35333457422428394	[959,748]	[1418,1525,1269]	5	hSpCas9	negative selection	4864234
31217626	31217648	21	+	27760321	HT29	viability after 7 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-1.1922860764987226	[865,675]	[431,481,387]	-9	hSpCas9	negative selection	4864235
31225874	31225896	21	+	27760321	HT29	viability after 7 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.11088156251091191	[398,311]	[461,553,263]	-2	hSpCas9	negative selection	4864236
31251986	31252008	21	-	27760321	HT29	viability after 7 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	-0.22807111294277096	[481,375]	[534,409,475]	-3	hSpCas9	negative selection	4864237
31252097	31252119	21	+	27760321	HT29	viability after 7 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.46636966434952615	[565,441]	[973,956,768]	7	hSpCas9	negative selection	4864238
31210082	31210104	21	+	27760321	HT29	viability after 25 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.24603593699827475	[959,748]	[1255,1046,1163]	2	hSpCas9	negative selection	4947697
31217626	31217648	21	+	27760321	HT29	viability after 25 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.8323225936390013	[865,675]	[554,421,503]	-6	hSpCas9	negative selection	4947698
31225874	31225896	21	+	27760321	HT29	viability after 25 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.04330233363130667	[398,311]	[430,440,297]	0	hSpCas9	negative selection	4947699
31251986	31252008	21	-	27760321	HT29	viability after 25 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.14093665094252505	[481,375]	[526,594,494]	1	hSpCas9	negative selection	4947700
31252097	31252119	21	+	27760321	HT29	viability after 25 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.15832754426035828	[565,441]	[673,457,810]	1	hSpCas9	negative selection	4947701
31210082	31210104	21	+	27760321	HT29	viability after 22 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.4722930950522295	[959,748]	[1643,1278,1178]	5	hSpCas9	negative selection	5031160
31217626	31217648	21	+	27760321	HT29	viability after 22 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.7762896588602864	[865,675]	[377,673,512]	-6	hSpCas9	negative selection	5031161
31225874	31225896	21	+	27760321	HT29	viability after 22 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	0.275229442310115	[398,311]	[632,416,437]	3	hSpCas9	negative selection	5031162
31251986	31252008	21	-	27760321	HT29	viability after 22 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.3137076706956188	[481,375]	[452,842,556]	3	hSpCas9	negative selection	5031163
31252097	31252119	21	+	27760321	HT29	viability after 22 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.17047388631366317	[565,441]	[412,569,993]	1	hSpCas9	negative selection	5031164
31210082	31210104	21	+	27760321	HT29	viability after 19 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.2792728328348766	[959,748]	[1875,959,807]	2	hSpCas9	negative selection	5114623
31217626	31217648	21	+	27760321	HT29	viability after 19 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.6843169070524964	[865,675]	[756,478,435]	-5	hSpCas9	negative selection	5114624
31225874	31225896	21	+	27760321	HT29	viability after 19 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	0.0034949459486719736	[398,311]	[548,297,390]	0	hSpCas9	negative selection	5114625
31251986	31252008	21	-	27760321	HT29	viability after 19 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.13432970916182563	[481,375]	[568,394,649]	1	hSpCas9	negative selection	5114626
31252097	31252119	21	+	27760321	HT29	viability after 19 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.48695138604934535	[565,441]	[759,527,1117]	5	hSpCas9	negative selection	5114627
31210082	31210104	21	+	27760321	HT29	viability after 16 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.5098370389886788	[959,748]	[1334,1131,1619]	6	hSpCas9	negative selection	5198086
31217626	31217648	21	+	27760321	HT29	viability after 16 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-1.1667534836627913	[865,675]	[350,478,316]	-7	hSpCas9	negative selection	5198087
31225874	31225896	21	+	27760321	HT29	viability after 16 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.034800208550137865	[398,311]	[316,468,369]	0	hSpCas9	negative selection	5198088
31251986	31252008	21	-	27760321	HT29	viability after 16 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.09262433757563149	[481,375]	[507,545,479]	1	hSpCas9	negative selection	5198089
31252097	31252119	21	+	27760321	HT29	viability after 16 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.23592927746339126	[565,441]	[601,712,669]	2	hSpCas9	negative selection	5198090
31210082	31210104	21	+	27760321	HT29	viability after 13 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.19157035075787565	[959,748]	[1276,992,1125]	2	hSpCas9	negative selection	5281549
31217626	31217648	21	+	27760321	HT29	viability after 13 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-1.163020459560914	[865,675]	[248,573,376]	-8	hSpCas9	negative selection	5281550
31225874	31225896	21	+	27760321	HT29	viability after 13 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	0.13960970217554505	[398,311]	[733,388,251]	1	hSpCas9	negative selection	5281551
31251986	31252008	21	-	27760321	HT29	viability after 13 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	-0.0023260381688994802	[481,375]	[503,395,584]	0	hSpCas9	negative selection	5281552
31252097	31252119	21	+	27760321	HT29	viability after 13 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.48606707088744333	[565,441]	[930,919,617]	6	hSpCas9	negative selection	5281553
31210082	31210104	21	+	27760321	HT29	viability after 10 days	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.34576776443023993	[959,748]	[1381,1239,1439]	5	hSpCas9	negative selection	5365012
31217626	31217648	21	+	27760321	HT29	viability after 10 days	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	-0.6499169988732968	[865,675]	[647,849,354]	-6	hSpCas9	negative selection	5365013
31225874	31225896	21	+	27760321	HT29	viability after 10 days	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	-0.2577847784184812	[398,311]	[397,383,332]	-3	hSpCas9	negative selection	5365014
31251986	31252008	21	-	27760321	HT29	viability after 10 days	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.045773784989990296	[481,375]	[554,580,523]	0	hSpCas9	negative selection	5365015
31252097	31252119	21	+	27760321	HT29	viability after 10 days	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.2464125924673502	[565,441]	[511,983,749]	3	hSpCas9	negative selection	5365016
31210082	31210104	21	+	27760321	MOLM13	viability	CCTGGCCGGACGACCGTCAGGG	TIAM1	ENSG00000156299	0.4423830223007901	[1141,959]	[759,838]	3	hSpCas9	negative selection	5448475
31217626	31217648	21	+	27760321	MOLM13	viability	CTTCGCTTGCTCGCGGATCTGG	TIAM1	ENSG00000156299	0.02968113452378618	[668,865]	[553,357]	0	hSpCas9	negative selection	5448476
31225874	31225896	21	+	27760321	MOLM13	viability	TGGTGCCTCGCGACCGCAGTGG	TIAM1	ENSG00000156299	1.1468464083030971	[380,398]	[398,566]	7	hSpCas9	negative selection	5448477
31251986	31252008	21	-	27760321	MOLM13	viability	GGTGTACGAGAACTTCCGGCGG	TIAM1	ENSG00000156299	0.3773151802623055	[513,481]	[523,229]	2	hSpCas9	negative selection	5448478
31252097	31252119	21	+	27760321	MOLM13	viability	GGCATTAGATCGCCTGGACAGG	TIAM1	ENSG00000156299	0.023212537966269098	[679,565]	[675,82]	0	hSpCas9	negative selection	5448479
31559089	31559112	21	-	27661255	K562	viability	GGGGCCCTGACAGCTCCGATTGG	TIAM1	ENSG00000156299	0.17057545462066703	[1662,1640]	[1693,1307]	6	dCas9-KRAB	negative selection	5517272
31245584	31245607	21	-	27260156	BXPC3	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6449540110449624	[770]	[1138,1152,1350,1432]	9	hSpCas9	negative selection	5575520
31252123	31252146	21	-	27260156	BXPC3	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.002652922011012304	[283]	[203,275,371,355]	0	hSpCas9	negative selection	5575521
31251868	31251891	21	+	27260156	BXPC3	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.43771258944936176	[356]	[569,308,647,497]	8	hSpCas9	negative selection	5575522
31462546	31462569	21	-	27260156	BXPC3	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.6706179523880016	[219]	[108,154,120,201]	-8	hSpCas9	negative selection	5588008
31225879	31225902	21	+	27260156	BXPC3	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.24109333458088678	[235]	[350,219,277,315]	5	hSpCas9	negative selection	5639773
31225851	31225874	21	+	27260156	BXPC3	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.10150842845130575	[552]	[536,531,449,644]	-2	hSpCas9	negative selection	5639774
31245592	31245615	21	+	27260156	BXPC3	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.1696375448426227	[477]	[486,650,556,550]	4	hSpCas9	negative selection	5639775
31245584	31245607	21	-	27260156	A673	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6366220413416767	[770]	[1405,1428,1377,1543]	9	hSpCas9	negative selection	5696771
31252123	31252146	21	-	27260156	A673	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.2338752196864965	[283]	[296,326,209,327]	-5	hSpCas9	negative selection	5696772
31251868	31251891	21	+	27260156	A673	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.3679067339018064	[356]	[569,558,466,621]	8	hSpCas9	negative selection	5696773
31462546	31462569	21	-	27260156	A673	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.18811231349496982	[219]	[369,305,243,290]	4	hSpCas9	negative selection	5709259
31225879	31225902	21	+	27260156	A673	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.4134299509110436	[235]	[366,337,385,419]	8	hSpCas9	negative selection	5761024
31225851	31225874	21	+	27260156	A673	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.05126620064672488	[552]	[755,566,678,570]	-1	hSpCas9	negative selection	5761025
31245592	31245615	21	+	27260156	A673	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.13663581017413395	[477]	[702,560,559,713]	3	hSpCas9	negative selection	5761026
31245584	31245607	21	-	27260156	A375	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.8926910380102754	[770]	[1911,1731,1741,1344]	9	hSpCas9	negative selection	5818022
31252123	31252146	21	-	27260156	A375	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.259376066798696	[283]	[348,352,488,389]	4	hSpCas9	negative selection	5818023
31251868	31251891	21	+	27260156	A375	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.4838302505287264	[356]	[562,648,569,559]	7	hSpCas9	negative selection	5818024
31462546	31462569	21	-	27260156	A375	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.274454930173601	[219]	[322,287,317,309]	4	hSpCas9	negative selection	5830510
31225879	31225902	21	+	27260156	A375	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.6270098969882192	[235]	[504,472,338,394]	8	hSpCas9	negative selection	5882275
31225851	31225874	21	+	27260156	A375	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.12360575524011122	[552]	[458,1086,627,690]	1	hSpCas9	negative selection	5882276
31245592	31245615	21	+	27260156	A375	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.08170464125434246	[477]	[591,816,489,503]	1	hSpCas9	negative selection	5882277
31245584	31245607	21	-	27260156	COLO741	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6736060152995479	[770]	[1654,1416,1639]	9	hSpCas9	negative selection	5939273
31252123	31252146	21	-	27260156	COLO741	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.0846355541263476	[283]	[332,469,348]	1	hSpCas9	negative selection	5939274
31251868	31251891	21	+	27260156	COLO741	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	-0.02459780942940243	[356]	[438,462,441]	0	hSpCas9	negative selection	5939275
31462546	31462569	21	-	27260156	COLO741	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.7843064114203144	[219]	[131,153,197]	-9	hSpCas9	negative selection	5951761
31225879	31225902	21	+	27260156	COLO741	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.028185270466700496	[235]	[349,221,349]	0	hSpCas9	negative selection	6003526
31225851	31225874	21	+	27260156	COLO741	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.22155189222571772	[552]	[872,793,807]	5	hSpCas9	negative selection	6003527
31245592	31245615	21	+	27260156	COLO741	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.09665091439483109	[477]	[607,706,639]	2	hSpCas9	negative selection	6003528
31245584	31245607	21	-	27260156	CAL120	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.8916619664738382	[770]	[2490,1548,1412]	9	hSpCas9	negative selection	6060524
31252123	31252146	21	-	27260156	CAL120	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.3945891126090921	[283]	[361,433,579]	6	hSpCas9	negative selection	6060525
31251868	31251891	21	+	27260156	CAL120	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.5935780428959551	[356]	[541,583,861]	8	hSpCas9	negative selection	6060526
31462546	31462569	21	-	27260156	CAL120	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.7652525536140127	[219]	[188,117,179]	-8	hSpCas9	negative selection	6073012
31225879	31225902	21	+	27260156	CAL120	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.10040851203330592	[235]	[535,256,186]	1	hSpCas9	negative selection	6124777
31225851	31225874	21	+	27260156	CAL120	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.0891550034694629	[552]	[566,913,450]	-1	hSpCas9	negative selection	6124778
31245592	31245615	21	+	27260156	CAL120	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.07469694963659743	[477]	[800,517,586]	1	hSpCas9	negative selection	6124779
31245584	31245607	21	-	27260156	CADOES1	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.8077247631627166	[770]	[1199,1218,1291,1311]	9	hSpCas9	negative selection	6181775
31252123	31252146	21	-	27260156	CADOES1	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.5431090154605628	[283]	[127,253,171,170]	-7	hSpCas9	negative selection	6181776
31251868	31251891	21	+	27260156	CADOES1	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.3571366251677293	[356]	[430,501,325,442]	6	hSpCas9	negative selection	6181777
31462546	31462569	21	-	27260156	CADOES1	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.23122544149281676	[219]	[202,317,224,213]	4	hSpCas9	negative selection	6194263
31225879	31225902	21	+	27260156	CADOES1	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.008431459640313221	[235]	[174,230,222,244]	0	hSpCas9	negative selection	6246028
31225851	31225874	21	+	27260156	CADOES1	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.03077204238886999	[552]	[475,596,466,472]	0	hSpCas9	negative selection	6246029
31245592	31245615	21	+	27260156	CADOES1	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.19325193270778435	[477]	[533,614,384,498]	3	hSpCas9	negative selection	6246030
31245584	31245607	21	-	27260156	EWS502	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6892866098997036	[770]	[1391,1270,1261,1329]	9	hSpCas9	negative selection	6303026
31252123	31252146	21	-	27260156	EWS502	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.10968365902484456	[283]	[347,380,375,176]	2	hSpCas9	negative selection	6303027
31251868	31251891	21	+	27260156	EWS502	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.0008244389153131415	[356]	[298,295,494,440]	0	hSpCas9	negative selection	6303028
31462546	31462569	21	-	27260156	EWS502	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.1855963926191344	[219]	[159,181,233,252]	-3	hSpCas9	negative selection	6315514
31225879	31225902	21	+	27260156	EWS502	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.1510861290714931	[235]	[193,294,152,259]	-3	hSpCas9	negative selection	6367279
31225851	31225874	21	+	27260156	EWS502	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.4806755284295948	[552]	[818,831,828,782]	8	hSpCas9	negative selection	6367280
31245592	31245615	21	+	27260156	EWS502	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.30324575772102896	[477]	[581,645,729,537]	5	hSpCas9	negative selection	6367281
31245584	31245607	21	-	27260156	EW8	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6559205815028238	[770]	[1153,1071,851,898]	9	hSpCas9	negative selection	6424277
31252123	31252146	21	-	27260156	EW8	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.434612377651982	[283]	[348,246,365,275]	7	hSpCas9	negative selection	6424278
31251868	31251891	21	+	27260156	EW8	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.13333756751695708	[356]	[277,228,390,352]	2	hSpCas9	negative selection	6424279
31462546	31462569	21	-	27260156	EW8	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.8222437412813137	[219]	[113,121,56,118]	-8	hSpCas9	negative selection	6436765
31225879	31225902	21	+	27260156	EW8	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.059531684951302344	[235]	[156,140,166,267]	-1	hSpCas9	negative selection	6488530
31225851	31225874	21	+	27260156	EW8	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.11505742037410852	[552]	[558,560,448,385]	2	hSpCas9	negative selection	6488531
31245592	31245615	21	+	27260156	EW8	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.23933980778389116	[477]	[659,341,401,454]	4	hSpCas9	negative selection	6488532
31245584	31245607	21	-	27260156	CORL105	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.8320146507403082	[770]	[1559,1370,1991,1566]	9	hSpCas9	negative selection	6545528
31252123	31252146	21	-	27260156	CORL105	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.0017402432582203087	[283]	[291,278,297,452]	0	hSpCas9	negative selection	6545529
31251868	31251891	21	+	27260156	CORL105	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.24440495943004467	[356]	[509,347,644,503]	4	hSpCas9	negative selection	6545530
31462546	31462569	21	-	27260156	CORL105	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.25397535995544374	[219]	[385,172,278,390]	5	hSpCas9	negative selection	6558016
31225879	31225902	21	+	27260156	CORL105	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.15187261010631303	[235]	[287,299,368,279]	3	hSpCas9	negative selection	6609781
31225851	31225874	21	+	27260156	CORL105	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.3360545239274066	[552]	[435,536,431,629]	-6	hSpCas9	negative selection	6609782
31245592	31245615	21	+	27260156	CORL105	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.14696849175048685	[477]	[491,522,557,455]	-3	hSpCas9	negative selection	6609783
31245584	31245607	21	-	27260156	HS294T	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.1424748228835924	[770]	[771,509,624,728]	9	hSpCas9	negative selection	6666779
31252123	31252146	21	-	27260156	HS294T	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.18882638697153442	[283]	[128,100,83,198]	2	hSpCas9	negative selection	6666780
31251868	31251891	21	+	27260156	HS294T	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	1.2987184258878068	[356]	[323,264,323,469]	9	hSpCas9	negative selection	6666781
31462546	31462569	21	-	27260156	HS294T	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.34458337361305347	[219]	[23,64,55,138]	-5	hSpCas9	negative selection	6679267
31225879	31225902	21	+	27260156	HS294T	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.6767890307844693	[235]	[80,261,77,167]	8	hSpCas9	negative selection	6731032
31225851	31225874	21	+	27260156	HS294T	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.03696285330095203	[552]	[151,252,172,268]	0	hSpCas9	negative selection	6731033
31245592	31245615	21	+	27260156	HS294T	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.29339323869671835	[477]	[147,133,327,321]	4	hSpCas9	negative selection	6731034
31245584	31245607	21	-	27260156	HCC44	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6589209761200358	[770]	[1318,1056,1717,1496]	9	hSpCas9	negative selection	6788030
31252123	31252146	21	-	27260156	HCC44	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.35400161752007625	[283]	[645,314,212,463]	6	hSpCas9	negative selection	6788031
31251868	31251891	21	+	27260156	HCC44	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.6051112255991812	[356]	[891,657,369,511]	8	hSpCas9	negative selection	6788032
31462546	31462569	21	-	27260156	HCC44	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.33257150121632195	[219]	[247,230,235,83]	-5	hSpCas9	negative selection	6800518
31225879	31225902	21	+	27260156	HCC44	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.10243499716641336	[235]	[236,120,330,331]	-2	hSpCas9	negative selection	6852283
31225851	31225874	21	+	27260156	HCC44	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.06669723187390297	[552]	[628,683,558,498]	-1	hSpCas9	negative selection	6852284
31245592	31245615	21	+	27260156	HCC44	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.23095666122582756	[477]	[590,444,776,762]	3	hSpCas9	negative selection	6852285
31245584	31245607	21	-	27260156	G402	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.00724291195283	[770]	[2439,1665,2347,1202]	9	hSpCas9	negative selection	6909281
31252123	31252146	21	-	27260156	G402	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.22427914741104282	[283]	[254,286,361,671]	3	hSpCas9	negative selection	6909282
31251868	31251891	21	+	27260156	G402	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.5503836899266095	[356]	[1064,764,354,442]	6	hSpCas9	negative selection	6909283
31462546	31462569	21	-	27260156	G402	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.3973333915214571	[219]	[462,330,250,380]	5	hSpCas9	negative selection	6921769
31225879	31225902	21	+	27260156	G402	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.3674588388039468	[235]	[410,348,421,309]	4	hSpCas9	negative selection	6973534
31225851	31225874	21	+	27260156	G402	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.25026868972677857	[552]	[692,477,647,465]	-3	hSpCas9	negative selection	6973535
31245592	31245615	21	+	27260156	G402	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.6494820217534033	[477]	[1460,432,645,1154]	7	hSpCas9	negative selection	6973536
31245584	31245607	21	-	27260156	L33	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.8770194695182735	[770]	[1259,608,890,1502]	9	hSpCas9	negative selection	7030532
31252123	31252146	21	-	27260156	L33	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.3037631013896791	[283]	[311,136,186,457]	6	hSpCas9	negative selection	7030533
31251868	31251891	21	+	27260156	L33	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.5064384994308755	[356]	[304,242,351,574]	8	hSpCas9	negative selection	7030534
31462546	31462569	21	-	27260156	L33	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.28380217782740846	[219]	[169,81,123,155]	-6	hSpCas9	negative selection	7043020
31225879	31225902	21	+	27260156	L33	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.14728451768248174	[235]	[251,118,141,276]	3	hSpCas9	negative selection	7094785
31225851	31225874	21	+	27260156	L33	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.16649735412025993	[552]	[547,244,447,625]	3	hSpCas9	negative selection	7094786
31245592	31245615	21	+	27260156	L33	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.08649511859663833	[477]	[422,184,309,433]	-2	hSpCas9	negative selection	7094787
31245584	31245607	21	-	27260156	K562	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6940486473632238	[770]	[916,1205,1176,1111]	8	hSpCas9	negative selection	7151783
31252123	31252146	21	-	27260156	K562	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.07221516090674407	[283]	[148,228,370,204]	-1	hSpCas9	negative selection	7151784
31251868	31251891	21	+	27260156	K562	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.34267596081769386	[356]	[647,323,413,252]	4	hSpCas9	negative selection	7151785
31462546	31462569	21	-	27260156	K562	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.41684178612045986	[219]	[187,158,175,73]	-5	hSpCas9	negative selection	7164271
31225879	31225902	21	+	27260156	K562	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.290218472193597	[235]	[250,259,111,82]	-4	hSpCas9	negative selection	7216036
31225851	31225874	21	+	27260156	K562	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.27634623957369947	[552]	[512,435,411,282]	-3	hSpCas9	negative selection	7216037
31245592	31245615	21	+	27260156	K562	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.35404151614578566	[477]	[541,411,648,554]	4	hSpCas9	negative selection	7216038
31245584	31245607	21	-	27260156	HT29	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.5738955355075842	[770]	[1425,1485,1430,1254]	9	hSpCas9	negative selection	7273034
31252123	31252146	21	-	27260156	HT29	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.0246758053727979	[283]	[381,405,361,227]	0	hSpCas9	negative selection	7273035
31251868	31251891	21	+	27260156	HT29	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.12772498430528934	[356]	[601,562,382,374]	2	hSpCas9	negative selection	7273036
31462546	31462569	21	-	27260156	HT29	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.5567979973968593	[219]	[239,123,175,184]	-7	hSpCas9	negative selection	7285522
31225879	31225902	21	+	27260156	HT29	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.11303365781370334	[235]	[257,235,267,448]	2	hSpCas9	negative selection	7337287
31225851	31225874	21	+	27260156	HT29	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.14778273221108124	[552]	[645,682,574,536]	-3	hSpCas9	negative selection	7337288
31245592	31245615	21	+	27260156	HT29	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.04212092355118576	[477]	[756,619,545,492]	0	hSpCas9	negative selection	7337289
31245584	31245607	21	-	27260156	MHHES1	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.594866185725668	[770]	[1498,1546,1072,1173]	8	hSpCas9	negative selection	7394285
31252123	31252146	21	-	27260156	MHHES1	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.2263364879279981	[283]	[514,352,405,256]	4	hSpCas9	negative selection	7394286
31251868	31251891	21	+	27260156	MHHES1	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.4840432230511017	[356]	[292,768,615,549]	8	hSpCas9	negative selection	7394287
31462546	31462569	21	-	27260156	MHHES1	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.6824613712081646	[219]	[571,368,514,192]	9	hSpCas9	negative selection	7406773
31225879	31225902	21	+	27260156	MHHES1	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.2745141678904478	[235]	[458,315,324,218]	5	hSpCas9	negative selection	7458538
31225851	31225874	21	+	27260156	MHHES1	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.20215412223834214	[552]	[469,617,522,540]	-4	hSpCas9	negative selection	7458539
31245592	31245615	21	+	27260156	MHHES1	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.14956729455696757	[477]	[481,516,748,603]	2	hSpCas9	negative selection	7458540
31245584	31245607	21	-	27260156	MEWO	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.3835396508827217	[770]	[1119,824,912]	7	hSpCas9	negative selection	7515536
31252123	31252146	21	-	27260156	MEWO	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.0888808804818848	[283]	[307,185,266]	-2	hSpCas9	negative selection	7515537
31251868	31251891	21	+	27260156	MEWO	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.4154129253044095	[356]	[293,422,589]	8	hSpCas9	negative selection	7515538
31462546	31462569	21	-	27260156	MEWO	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.1343148968850294	[219]	[224,145,198]	-3	hSpCas9	negative selection	7528024
31225879	31225902	21	+	27260156	MEWO	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.4315711749651232	[235]	[387,248,273]	8	hSpCas9	negative selection	7579789
31225851	31225874	21	+	27260156	MEWO	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.051208129775361294	[552]	[622,515,485]	1	hSpCas9	negative selection	7579790
31245592	31245615	21	+	27260156	MEWO	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.15374254665900192	[477]	[675,483,366]	3	hSpCas9	negative selection	7579791
31245584	31245607	21	-	27260156	LNCAPCLONEFGC	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.7800415355260678	[770]	[1300,1073,1234,1197]	9	hSpCas9	negative selection	7636787
31252123	31252146	21	-	27260156	LNCAPCLONEFGC	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.07563974709010923	[283]	[322,191,341,241]	1	hSpCas9	negative selection	7636788
31251868	31251891	21	+	27260156	LNCAPCLONEFGC	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.38424292804221977	[356]	[388,282,678,384]	6	hSpCas9	negative selection	7636789
31462546	31462569	21	-	27260156	LNCAPCLONEFGC	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.1414402300271379	[219]	[299,267,122,168]	2	hSpCas9	negative selection	7649275
31225879	31225902	21	+	27260156	LNCAPCLONEFGC	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.2507512552253782	[235]	[269,211,329,218]	4	hSpCas9	negative selection	7701040
31225851	31225874	21	+	27260156	LNCAPCLONEFGC	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.014254649429088523	[552]	[500,398,495,632]	0	hSpCas9	negative selection	7701041
31245592	31245615	21	+	27260156	LNCAPCLONEFGC	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.2900914039982515	[477]	[451,618,495,540]	4	hSpCas9	negative selection	7701042
31245584	31245607	21	-	27260156	PANC0327	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6696410143291175	[770]	[1234,686,1058,1439]	8	hSpCas9	negative selection	7758038
31252123	31252146	21	-	27260156	PANC0327	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.0010553905837122901	[283]	[182,262,168,385]	0	hSpCas9	negative selection	7758039
31251868	31251891	21	+	27260156	PANC0327	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.7042570379139315	[356]	[627,520,403,521]	8	hSpCas9	negative selection	7758040
31462546	31462569	21	-	27260156	PANC0327	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.9684825478146026	[219]	[219,70,62,58]	-8	hSpCas9	negative selection	7770526
31225879	31225902	21	+	27260156	PANC0327	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.2343973673521229	[235]	[409,267,171,146]	3	hSpCas9	negative selection	7822291
31225851	31225874	21	+	27260156	PANC0327	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.16067466978214354	[552]	[649,577,596,375]	2	hSpCas9	negative selection	7822292
31245592	31245615	21	+	27260156	PANC0327	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.07064126062029559	[477]	[442,345,470,367]	-1	hSpCas9	negative selection	7822293
31245584	31245607	21	-	27260156	NCIH2009	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.2211947156622132	[770]	[2868,2324,2409]	9	hSpCas9	negative selection	7879289
31252123	31252146	21	-	27260156	NCIH2009	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.557568629163917	[283]	[495,671,563]	7	hSpCas9	negative selection	7879290
31251868	31251891	21	+	27260156	NCIH2009	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.4910602527262806	[356]	[767,873,469]	6	hSpCas9	negative selection	7879291
31462546	31462569	21	-	27260156	NCIH2009	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.8250086367254623	[219]	[291,153,97]	-7	hSpCas9	negative selection	7891777
31225879	31225902	21	+	27260156	NCIH2009	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.25495630931652913	[235]	[519,323,361]	3	hSpCas9	negative selection	7943542
31225851	31225874	21	+	27260156	NCIH2009	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.27551538829363553	[552]	[1025,713,1085]	4	hSpCas9	negative selection	7943543
31245592	31245615	21	+	27260156	NCIH2009	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.027204800111837787	[477]	[912,484,620]	0	hSpCas9	negative selection	7943544
31245584	31245607	21	-	27260156	NCIH1373	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.209467515026991	[770]	[2784,1747,1347,599]	9	hSpCas9	negative selection	8000540
31252123	31252146	21	-	27260156	NCIH1373	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.012084149184143134	[283]	[410,264,208,111]	0	hSpCas9	negative selection	8000541
31251868	31251891	21	+	27260156	NCIH1373	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.691162812711549	[356]	[1001,562,507,149]	7	hSpCas9	negative selection	8000542
31462546	31462569	21	-	27260156	NCIH1373	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.22328787613888545	[219]	[161,173,362,34]	-2	hSpCas9	negative selection	8013028
31225879	31225902	21	+	27260156	NCIH1373	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.4950307081970723	[235]	[445,668,152,50]	5	hSpCas9	negative selection	8064793
31225851	31225874	21	+	27260156	NCIH1373	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.5643214532996811	[552]	[410,394,229,172]	-5	hSpCas9	negative selection	8064794
31245592	31245615	21	+	27260156	NCIH1373	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.10592138050026972	[477]	[817,430,624,124]	1	hSpCas9	negative selection	8064795
31245584	31245607	21	-	27260156	PATU8902	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	1.0933124675269834	[770]	[1814,3044,1465,3144]	9	hSpCas9	negative selection	8121791
31252123	31252146	21	-	27260156	PATU8902	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.561724206708417	[283]	[771,910,349,325]	6	hSpCas9	negative selection	8121792
31251868	31251891	21	+	27260156	PATU8902	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.5550167687237308	[356]	[223,707,986,964]	6	hSpCas9	negative selection	8121793
31462546	31462569	21	-	27260156	PATU8902	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-1.5657484761428695	[219]	[50,214,52,108]	-8	hSpCas9	negative selection	8134279
31225879	31225902	21	+	27260156	PATU8902	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.29576154244398734	[235]	[495,338,476,260]	3	hSpCas9	negative selection	8186044
31225851	31225874	21	+	27260156	PATU8902	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.04245382765361	[552]	[867,759,665,705]	0	hSpCas9	negative selection	8186045
31245592	31245615	21	+	27260156	PATU8902	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.23011897764522324	[477]	[1305,593,394,932]	2	hSpCas9	negative selection	8186046
31245584	31245607	21	-	27260156	PANC1	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6225334801158128	[770]	[1019,1068,1129,876]	8	hSpCas9	negative selection	8243042
31252123	31252146	21	-	27260156	PANC1	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.35259141418129636	[283]	[202,307,135,144]	-5	hSpCas9	negative selection	8243043
31251868	31251891	21	+	27260156	PANC1	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	-0.24351533246585405	[356]	[250,324,262,213]	-4	hSpCas9	negative selection	8243044
31462546	31462569	21	-	27260156	PANC1	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.5922983931449926	[219]	[61,225,119,114]	-7	hSpCas9	negative selection	8255530
31225879	31225902	21	+	27260156	PANC1	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.35674730202617255	[235]	[311,305,140,278]	6	hSpCas9	negative selection	8307295
31225851	31225874	21	+	27260156	PANC1	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.2152088133955611	[552]	[362,669,465,699]	3	hSpCas9	negative selection	8307296
31245592	31245615	21	+	27260156	PANC1	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.3047365063661552	[477]	[540,798,514,264]	5	hSpCas9	negative selection	8307297
31245584	31245607	21	-	27260156	PANC0813	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.9616138209048563	[770]	[1872,1609,1721,1851]	9	hSpCas9	negative selection	8364293
31252123	31252146	21	-	27260156	PANC0813	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.21883758273390508	[283]	[351,401,508,291]	3	hSpCas9	negative selection	8364294
31251868	31251891	21	+	27260156	PANC0813	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.5254037966668136	[356]	[643,758,614,409]	8	hSpCas9	negative selection	8364295
31462546	31462569	21	-	27260156	PANC0813	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.9690002417320971	[219]	[98,109,182,132]	-8	hSpCas9	negative selection	8376781
31225879	31225902	21	+	27260156	PANC0813	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	-0.2458593402287883	[235]	[308,187,251,194]	-4	hSpCas9	negative selection	8428546
31225851	31225874	21	+	27260156	PANC0813	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.04148970205847061	[552]	[596,639,728,558]	0	hSpCas9	negative selection	8428547
31245592	31245615	21	+	27260156	PANC0813	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.0902941196856343	[477]	[646,423,557,492]	-1	hSpCas9	negative selection	8428548
31245584	31245607	21	-	27260156	RDES	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6719562638450675	[770]	[1264,1151,1680,1604]	9	hSpCas9	negative selection	8485544
31252123	31252146	21	-	27260156	RDES	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.029672952939034825	[283]	[262,249,374,483]	0	hSpCas9	negative selection	8485545
31251868	31251891	21	+	27260156	RDES	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.27051107240863836	[356]	[415,511,487,576]	4	hSpCas9	negative selection	8485546
31462546	31462569	21	-	27260156	RDES	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.2584747724933991	[219]	[136,124,240,390]	-4	hSpCas9	negative selection	8498032
31225879	31225902	21	+	27260156	RDES	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.23144939030251988	[235]	[201,350,424,312]	4	hSpCas9	negative selection	8549797
31225851	31225874	21	+	27260156	RDES	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.1341646951902703	[552]	[481,598,631,612]	-2	hSpCas9	negative selection	8549798
31245592	31245615	21	+	27260156	RDES	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.1493076157713834	[477]	[578,585,570,703]	2	hSpCas9	negative selection	8549799
31245584	31245607	21	-	27260156	PC3	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6684129708245287	[770]	[781,1175,2341,1090]	9	hSpCas9	negative selection	8606795
31252123	31252146	21	-	27260156	PC3	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.16317900715705325	[283]	[165,345,446,400]	3	hSpCas9	negative selection	8606796
31251868	31251891	21	+	27260156	PC3	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.13359345483471236	[356]	[220,379,774,374]	3	hSpCas9	negative selection	8606797
31462546	31462569	21	-	27260156	PC3	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.3453414880617798	[219]	[187,55,440,78]	-7	hSpCas9	negative selection	8619283
31225879	31225902	21	+	27260156	PC3	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.0231396420316351	[235]	[205,226,309,223]	0	hSpCas9	negative selection	8671048
31225851	31225874	21	+	27260156	PC3	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.01884857932615233	[552]	[258,657,709,695]	0	hSpCas9	negative selection	8671049
31245592	31245615	21	+	27260156	PC3	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.033104630614070645	[477]	[324,451,776,533]	0	hSpCas9	negative selection	8671050
31245584	31245607	21	-	27260156	PATU8988T	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6817596266578868	[770]	[1250,1059,1128,1339]	9	hSpCas9	negative selection	8728046
31252123	31252146	21	-	27260156	PATU8988T	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.0764713566499593	[283]	[120,209,400,305]	-1	hSpCas9	negative selection	8728047
31251868	31251891	21	+	27260156	PATU8988T	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.6636367579568992	[356]	[419,470,581,718]	9	hSpCas9	negative selection	8728048
31462546	31462569	21	-	27260156	PATU8988T	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.9251659492546442	[219]	[108,201,46,97]	-8	hSpCas9	negative selection	8740534
31225879	31225902	21	+	27260156	PATU8988T	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.3259067305006369	[235]	[312,367,345,108]	5	hSpCas9	negative selection	8792299
31225851	31225874	21	+	27260156	PATU8988T	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.2196440566538263	[552]	[605,475,340,411]	-4	hSpCas9	negative selection	8792300
31245592	31245615	21	+	27260156	PATU8988T	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.3279025517892325	[477]	[583,764,376,615]	5	hSpCas9	negative selection	8792301
31245584	31245607	21	-	27260156	T47D	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6284345650705411	[770]	[1260,1450,1419,1415]	9	hSpCas9	negative selection	8849297
31252123	31252146	21	-	27260156	T47D	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	-0.14565311486118226	[283]	[256,268,382,287]	-3	hSpCas9	negative selection	8849298
31251868	31251891	21	+	27260156	T47D	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.23019642752033465	[356]	[559,405,532,457]	5	hSpCas9	negative selection	8849299
31462546	31462569	21	-	27260156	T47D	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.2872482980559854	[219]	[232,199,201,205]	-6	hSpCas9	negative selection	8861785
31225879	31225902	21	+	27260156	T47D	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.2317010249543604	[235]	[274,304,277,438]	5	hSpCas9	negative selection	8913550
31225851	31225874	21	+	27260156	T47D	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.08632039139661743	[552]	[679,541,483,732]	-2	hSpCas9	negative selection	8913551
31245592	31245615	21	+	27260156	T47D	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.29324799127294093	[477]	[628,884,638,554]	6	hSpCas9	negative selection	8913552
31245584	31245607	21	-	27260156	SU8686	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.7267512927634777	[770]	[1191,1091,1235,1617]	9	hSpCas9	negative selection	8970548
31252123	31252146	21	-	27260156	SU8686	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.14439421844901434	[283]	[262,329,294,365]	2	hSpCas9	negative selection	8970549
31251868	31251891	21	+	27260156	SU8686	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.7173070806718362	[356]	[608,395,659,700]	9	hSpCas9	negative selection	8970550
31462546	31462569	21	-	27260156	SU8686	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.7595969686350048	[219]	[126,131,76,185]	-8	hSpCas9	negative selection	8983036
31225879	31225902	21	+	27260156	SU8686	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.4656086079387992	[235]	[258,257,263,561]	7	hSpCas9	negative selection	9034801
31225851	31225874	21	+	27260156	SU8686	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.2705204183969183	[552]	[530,519,735,932]	4	hSpCas9	negative selection	9034802
31245592	31245615	21	+	27260156	SU8686	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.04407237271583397	[477]	[413,437,447,558]	-1	hSpCas9	negative selection	9034803
31245584	31245607	21	-	27260156	SKES1	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.5929209358338791	[770]	[1309,1117,1286,951]	9	hSpCas9	negative selection	9091799
31252123	31252146	21	-	27260156	SKES1	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.08723392911481709	[283]	[274,331,231,355]	2	hSpCas9	negative selection	9091800
31251868	31251891	21	+	27260156	SKES1	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.3085748780851738	[356]	[390,575,404,401]	6	hSpCas9	negative selection	9091801
31462546	31462569	21	-	27260156	SKES1	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.42562320386254804	[219]	[203,145,145,159]	-7	hSpCas9	negative selection	9104287
31225879	31225902	21	+	27260156	SKES1	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.06154196312956728	[235]	[283,286,191,229]	1	hSpCas9	negative selection	9156052
31225851	31225874	21	+	27260156	SKES1	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.04240166161648243	[552]	[599,481,567,493]	-1	hSpCas9	negative selection	9156053
31245592	31245615	21	+	27260156	SKES1	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.23779333844858283	[477]	[624,633,502,505]	5	hSpCas9	negative selection	9156054
31245584	31245607	21	-	27260156	TOV112D	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.6593589338205973	[770]	[1160,1450,1228,1090]	9	hSpCas9	negative selection	9213050
31252123	31252146	21	-	27260156	TOV112D	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.33743720742784483	[283]	[452,428,365,217]	6	hSpCas9	negative selection	9213051
31251868	31251891	21	+	27260156	TOV112D	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.042877435510676576	[356]	[288,403,382,397]	0	hSpCas9	negative selection	9213052
31462546	31462569	21	-	27260156	TOV112D	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	0.2666585938256564	[219]	[155,479,181,284]	5	hSpCas9	negative selection	9225538
31225879	31225902	21	+	27260156	TOV112D	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.3847015100376814	[235]	[297,251,140,521]	7	hSpCas9	negative selection	9277303
31225851	31225874	21	+	27260156	TOV112D	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	0.35631697211402	[552]	[674,758,869,544]	6	hSpCas9	negative selection	9277304
31245592	31245615	21	+	27260156	TOV112D	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	-0.0719238734081155	[477]	[337,796,440,322]	-1	hSpCas9	negative selection	9277305
31245584	31245607	21	-	27260156	TC71	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.4742635130015723	[770]	[1064,1228,1093,1211]	9	hSpCas9	negative selection	9334301
31252123	31252146	21	-	27260156	TC71	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.024248757212660732	[283]	[208,332,396,297]	0	hSpCas9	negative selection	9334302
31251868	31251891	21	+	27260156	TC71	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.17611069612971947	[356]	[387,405,373,572]	4	hSpCas9	negative selection	9334303
31462546	31462569	21	-	27260156	TC71	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.30273949307886294	[219]	[161,156,196,252]	-7	hSpCas9	negative selection	9346789
31225879	31225902	21	+	27260156	TC71	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.14825672921028454	[235]	[329,315,216,257]	4	hSpCas9	negative selection	9398554
31225851	31225874	21	+	27260156	TC71	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.13866511190216324	[552]	[430,681,418,633]	-4	hSpCas9	negative selection	9398555
31245592	31245615	21	+	27260156	TC71	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.21219390257170262	[477]	[488,732,597,553]	5	hSpCas9	negative selection	9398556
31245584	31245607	21	-	27260156	TC32	viability	GCATCCCCAAACACGCCGTCTGG	TIAM1	ENSG00000156299	0.786778604900476	[770]	[936,1113,1707,1340]	9	hSpCas9	negative selection	9455552
31252123	31252146	21	-	27260156	TC32	viability	TGAAGGGGCCACTACCGACACGG	TIAM1	ENSG00000156299	0.17013226410678206	[283]	[277,244,344,348]	3	hSpCas9	negative selection	9455553
31251868	31251891	21	+	27260156	TC32	viability	CGGTCAGCAGGATGTCCGACTGG	TIAM1	ENSG00000156299	0.22426811325204907	[356]	[348,231,497,560]	4	hSpCas9	negative selection	9455554
31462546	31462569	21	-	27260156	TC32	viability	GATTGGTGCAGAAGTAATTGCAG	TIAM1	ENSG00000156299	-0.9212157007139645	[219]	[86,46,117,212]	-9	hSpCas9	negative selection	9468040
31225879	31225902	21	+	27260156	TC32	viability	CCTCGCGACCGCAGTGGCGCAGG	TIAM1	ENSG00000156299	0.5819759950585519	[235]	[308,221,325,504]	8	hSpCas9	negative selection	9519805
31225851	31225874	21	+	27260156	TC32	viability	GTCGGAGCGTGTCTTCCTTGTGG	TIAM1	ENSG00000156299	-0.14222844477786306	[552]	[424,423,522,516]	-3	hSpCas9	negative selection	9519806
31245592	31245615	21	+	27260156	TC32	viability	CGTGTTTGGGGATGCTGTTGTGG	TIAM1	ENSG00000156299	0.4013042964464014	[477]	[569,523,701,586]	7	hSpCas9	negative selection	9519807
31210111	31210134	21	+	27869803	HPAFII	viability after 27 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.4971002094345355	[406]	[271,326,NaN]	4	hSpCas9	negative selection	9579032
31217625	31217648	21	-	27869803	HPAFII	viability after 27 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	1.4086512137767415	[279]	[338,433,NaN]	9	hSpCas9	negative selection	9579033
31223447	31223470	21	-	27869803	HPAFII	viability after 27 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.3496478330408448	[311]	[125,130,NaN]	-3	hSpCas9	negative selection	9579034
31225866	31225889	21	-	27869803	HPAFII	viability after 27 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.13200834191409638	[172]	[100,67,NaN]	-1	hSpCas9	negative selection	9579035
31252045	31252068	21	+	27869803	HPAFII	viability after 27 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.6952692387622615	[271]	[362,121,NaN]	5	hSpCas9	negative selection	9579036
31266354	31266377	21	-	27869803	HPAFII	viability after 27 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.1171162753752363	[297]	[120,163,NaN]	-1	hSpCas9	negative selection	9579037
31210111	31210134	21	+	27869803	HPAFII	viability after 15 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.5530579597562096	[406]	[872,497,NaN]	6	hSpCas9	negative selection	9661481
31217625	31217648	21	-	27869803	HPAFII	viability after 15 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.7198491356072284	[279]	[761,329,NaN]	7	hSpCas9	negative selection	9661482
31223447	31223470	21	-	27869803	HPAFII	viability after 15 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.2047727208874333	[311]	[240,321,NaN]	-2	hSpCas9	negative selection	9661483
31225866	31225889	21	-	27869803	HPAFII	viability after 15 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.18669448859092602	[172]	[366,114,NaN]	2	hSpCas9	negative selection	9661484
31252045	31252068	21	+	27869803	HPAFII	viability after 15 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.5688332002797944	[271]	[588,336,NaN]	6	hSpCas9	negative selection	9661485
31266354	31266377	21	-	27869803	HPAFII	viability after 15 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.24356379310933315	[297]	[280,263,NaN]	-3	hSpCas9	negative selection	9661486
31210111	31210134	21	+	27869803	ASPC1	viability after 36 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.6401714803393969	[913]	[584,454,463]	6	hSpCas9	negative selection	9743930
31217625	31217648	21	-	27869803	ASPC1	viability after 36 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.4812256405232852	[852]	[297,587,356]	5	hSpCas9	negative selection	9743931
31223447	31223470	21	-	27869803	ASPC1	viability after 36 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.28213846179167984	[603]	[269,282,222]	3	hSpCas9	negative selection	9743932
31225866	31225889	21	-	27869803	ASPC1	viability after 36 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.5260841595752899	[620]	[328,378,243]	5	hSpCas9	negative selection	9743933
31252045	31252068	21	+	27869803	ASPC1	viability after 36 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	0.027846624024310304	[649]	[110,368,203]	0	hSpCas9	negative selection	9743934
31266354	31266377	21	-	27869803	ASPC1	viability after 36 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	-0.002810972920034517	[624]	[351,173,155]	0	hSpCas9	negative selection	9743935
31210111	31210134	21	+	27869803	PATU8988S	viability after 35 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.5211348972039591	[629]	[419,307,NaN]	6	hSpCas9	negative selection	9826379
31217625	31217648	21	-	27869803	PATU8988S	viability after 35 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.19795218341578003	[821]	[269,489,NaN]	2	hSpCas9	negative selection	9826380
31223447	31223470	21	-	27869803	PATU8988S	viability after 35 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.9956086350689793	[512]	[177,646,NaN]	8	hSpCas9	negative selection	9826381
31225866	31225889	21	-	27869803	PATU8988S	viability after 35 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.23662047409174336	[509]	[246,236,NaN]	2	hSpCas9	negative selection	9826382
31252045	31252068	21	+	27869803	PATU8988S	viability after 35 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.14790627629473438	[612]	[147,297,NaN]	-1	hSpCas9	negative selection	9826383
31266354	31266377	21	-	27869803	PATU8988S	viability after 35 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.4100778270891774	[492]	[599,454,NaN]	9	hSpCas9	negative selection	9826384
31210111	31210134	21	+	27869803	PATU8988S	viability after 31 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.5933045795000098	[629]	[367,392,NaN]	7	hSpCas9	negative selection	9908828
31217625	31217648	21	-	27869803	PATU8988S	viability after 31 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	0.2724326379091021	[821]	[255,573,NaN]	3	hSpCas9	negative selection	9908829
31223447	31223470	21	-	27869803	PATU8988S	viability after 31 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	0.4994831568953336	[512]	[198,403,NaN]	6	hSpCas9	negative selection	9908830
31225866	31225889	21	-	27869803	PATU8988S	viability after 31 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	0.40955926484912086	[509]	[259,282,NaN]	5	hSpCas9	negative selection	9908831
31252045	31252068	21	+	27869803	PATU8988S	viability after 31 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	-0.2248842307092922	[612]	[158,272,NaN]	-3	hSpCas9	negative selection	9908832
31266354	31266377	21	-	27869803	PATU8988S	viability after 31 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	1.27600605436294	[492]	[545,386,NaN]	9	hSpCas9	negative selection	9908833
31210111	31210134	21	+	27869803	HPAFII	viability after 35 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.8290903572597611	[406]	[342,391,NaN]	5	hSpCas9	negative selection	9991277
31217625	31217648	21	-	27869803	HPAFII	viability after 35 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	1.2524697584883935	[279]	[237,449,NaN]	8	hSpCas9	negative selection	9991278
31223447	31223470	21	-	27869803	HPAFII	viability after 35 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.30037638278602025	[311]	[60,203,NaN]	-2	hSpCas9	negative selection	9991279
31225866	31225889	21	-	27869803	HPAFII	viability after 35 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-0.5260151350377448	[172]	[57,63,NaN]	-3	hSpCas9	negative selection	9991280
31252045	31252068	21	+	27869803	HPAFII	viability after 35 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	1.0604066018235128	[271]	[400,158,NaN]	7	hSpCas9	negative selection	9991281
31266354	31266377	21	-	27869803	HPAFII	viability after 35 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.32428722727033016	[297]	[75,315,NaN]	2	hSpCas9	negative selection	9991282
31210111	31210134	21	+	27869803	HPAFII	viability after 31 days	ATTATTGGGCAGACAGAACCAGG	TIAM1	ENSG00000156299	0.8031548450864437	[406]	[332,469,NaN]	6	hSpCas9	negative selection	10073726
31217625	31217648	21	-	27869803	HPAFII	viability after 31 days	CCAGATCCGCGAGCAAGCGAAGG	TIAM1	ENSG00000156299	1.127023951150584	[279]	[291,398,NaN]	8	hSpCas9	negative selection	10073727
31223447	31223470	21	-	27869803	HPAFII	viability after 31 days	TCGACCAACGAAAGTGGCCATGG	TIAM1	ENSG00000156299	-0.2274091125702472	[311]	[83,220,NaN]	-1	hSpCas9	negative selection	10073728
31225866	31225889	21	-	27869803	HPAFII	viability after 31 days	GGTCGCGAGGCACCACCACAAGG	TIAM1	ENSG00000156299	-1.8745036450872776	[172]	[25,26,NaN]	-8	hSpCas9	negative selection	10073729
31252045	31252068	21	+	27869803	HPAFII	viability after 31 days	TGTCGCTGCCCACAAAGGCCCGG	TIAM1	ENSG00000156299	1.0016788298261028	[271]	[364,240,NaN]	7	hSpCas9	negative selection	10073730
31266354	31266377	21	-	27869803	HPAFII	viability after 31 days	CTTGGGTTCCGCCGAAGAGAAGG	TIAM1	ENSG00000156299	0.18014795376388	[297]	[110,274,NaN]	1	hSpCas9	negative selection	10073731
31266859	31266882	21	-	28162770	P31FUJ	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.03849981740301578	[115]	[139]	0	hSpCas9	negative selection	10250568
31251773	31251796	21	-	28162770	P31FUJ	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.27587092630626464	[169]	[164]	-3	hSpCas9	negative selection	10250569
31252170	31252193	21	-	28162770	P31FUJ	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	-0.2857510843633375	[110]	[106]	-3	hSpCas9	negative selection	10250570
31266823	31266846	21	+	28162770	P31FUJ	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.1351732579924202	[147]	[190]	1	hSpCas9	negative selection	10250571
31266582	31266605	21	-	28162770	P31FUJ	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.26469745505643816	[322]	[455]	3	hSpCas9	negative selection	10250572
31252024	31252047	21	-	28162770	P31FUJ	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.6733747958003602	[37]	[27]	-5	hSpCas9	negative selection	10250573
31252010	31252033	21	+	28162770	P31FUJ	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.021299076649407445	[539]	[643]	0	hSpCas9	negative selection	10250574
31251985	31252008	21	-	28162770	P31FUJ	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.6895177349430931	[198]	[144]	-5	hSpCas9	negative selection	10250575
31251943	31251966	21	-	28162770	P31FUJ	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	1.156240086331521	[41]	[109]	9	hSpCas9	negative selection	10250576
31251793	31251816	21	-	28162770	P31FUJ	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.5807255078346855	[195]	[153]	-5	hSpCas9	negative selection	10250577
31266859	31266882	21	-	28162770	TF1	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10419934
31251773	31251796	21	-	28162770	TF1	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10419935
31252170	31252193	21	-	28162770	TF1	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10419936
31266823	31266846	21	+	28162770	TF1	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10419937
31266582	31266605	21	-	28162770	TF1	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10419938
31252024	31252047	21	-	28162770	TF1	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10419939
31252010	31252033	21	+	28162770	TF1	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10419940
31251985	31252008	21	-	28162770	TF1	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10419941
31251943	31251966	21	-	28162770	TF1	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10419942
31251793	31251816	21	-	28162770	TF1	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10419943
31266859	31266882	21	-	28162770	SKM1	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.12422704553701386	[40]	[78]	1	hSpCas9	negative selection	10589300
31251773	31251796	21	-	28162770	SKM1	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.7854758219968915	[38]	[39]	-5	hSpCas9	negative selection	10589301
31252170	31252193	21	-	28162770	SKM1	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.7015602580350077	[23]	[68]	6	hSpCas9	negative selection	10589302
31266823	31266846	21	+	28162770	SKM1	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.28989118204889164	[30]	[66]	3	hSpCas9	negative selection	10589303
31266582	31266605	21	-	28162770	SKM1	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.05894563033423117	[100]	[185]	0	hSpCas9	negative selection	10589304
31252024	31252047	21	-	28162770	SKM1	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-1.8220016980220053	[15]	[7]	-8	hSpCas9	negative selection	10589305
31252010	31252033	21	+	28162770	SKM1	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.1466341310686593	[92]	[181]	1	hSpCas9	negative selection	10589306
31251985	31252008	21	-	28162770	SKM1	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.4069641987431617	[32]	[43]	-3	hSpCas9	negative selection	10589307
31251943	31251966	21	-	28162770	SKM1	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	3.277533975528909	[6]	[119]	9	hSpCas9	negative selection	10589308
31251793	31251816	21	-	28162770	SKM1	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.1939704754089634	[32]	[50]	-2	hSpCas9	negative selection	10589309
31266859	31266882	21	-	28162770	SKM1	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.12422704553701386	[40]	[78]	1	hSpCas9	negative selection	10758666
31251773	31251796	21	-	28162770	SKM1	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.7854758219968915	[38]	[39]	-5	hSpCas9	negative selection	10758667
31252170	31252193	21	-	28162770	SKM1	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.7015602580350077	[23]	[68]	6	hSpCas9	negative selection	10758668
31266823	31266846	21	+	28162770	SKM1	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.28989118204889164	[30]	[66]	3	hSpCas9	negative selection	10758669
31266582	31266605	21	-	28162770	SKM1	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.05894563033423117	[100]	[185]	0	hSpCas9	negative selection	10758670
31252024	31252047	21	-	28162770	SKM1	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-1.8220016980220053	[15]	[7]	-8	hSpCas9	negative selection	10758671
31252010	31252033	21	+	28162770	SKM1	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.1466341310686593	[92]	[181]	1	hSpCas9	negative selection	10758672
31251985	31252008	21	-	28162770	SKM1	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.4069641987431617	[32]	[43]	-3	hSpCas9	negative selection	10758673
31251943	31251966	21	-	28162770	SKM1	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	3.277533975528909	[6]	[119]	9	hSpCas9	negative selection	10758674
31251793	31251816	21	-	28162770	SKM1	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.1939704754089634	[32]	[50]	-2	hSpCas9	negative selection	10758675
31266859	31266882	21	-	28162770	PL21	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.6855664416595617	[109]	[76]	6	hSpCas9	negative selection	10928032
31251773	31251796	21	-	28162770	PL21	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.246116615400244	[108]	[39]	-2	hSpCas9	negative selection	10928033
31252170	31252193	21	-	28162770	PL21	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	1.3278951616876928	[107]	[117]	9	hSpCas9	negative selection	10928034
31266823	31266846	21	+	28162770	PL21	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.3272515323926594	[151]	[82]	3	hSpCas9	negative selection	10928035
31266582	31266605	21	-	28162770	PL21	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.18979767026786099	[279]	[138]	1	hSpCas9	negative selection	10928036
31252024	31252047	21	-	28162770	PL21	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	1.4923203659826303	[48]	[59]	9	hSpCas9	negative selection	10928037
31252010	31252033	21	+	28162770	PL21	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.797380444988913	[311]	[235]	6	hSpCas9	negative selection	10928038
31251985	31252008	21	-	28162770	PL21	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	1.4421124047952842	[114]	[135]	9	hSpCas9	negative selection	10928039
31251943	31251966	21	-	28162770	PL21	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.26333344097651423	[66]	[34]	2	hSpCas9	negative selection	10928040
31251793	31251816	21	-	28162770	PL21	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	1.7424577778019827	[102]	[149]	9	hSpCas9	negative selection	10928041
31266859	31266882	21	-	28162770	P31FUJ	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.03849981740301578	[115]	[139]	0	hSpCas9	negative selection	11097398
31251773	31251796	21	-	28162770	P31FUJ	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.27587092630626464	[169]	[164]	-3	hSpCas9	negative selection	11097399
31252170	31252193	21	-	28162770	P31FUJ	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	-0.2857510843633375	[110]	[106]	-3	hSpCas9	negative selection	11097400
31266823	31266846	21	+	28162770	P31FUJ	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.1351732579924202	[147]	[190]	1	hSpCas9	negative selection	11097401
31266582	31266605	21	-	28162770	P31FUJ	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.26469745505643816	[322]	[455]	3	hSpCas9	negative selection	11097402
31252024	31252047	21	-	28162770	P31FUJ	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.6733747958003602	[37]	[27]	-5	hSpCas9	negative selection	11097403
31252010	31252033	21	+	28162770	P31FUJ	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.021299076649407445	[539]	[643]	0	hSpCas9	negative selection	11097404
31251985	31252008	21	-	28162770	P31FUJ	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.6895177349430931	[198]	[144]	-5	hSpCas9	negative selection	11097405
31251943	31251966	21	-	28162770	P31FUJ	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	1.156240086331521	[41]	[109]	9	hSpCas9	negative selection	11097406
31251793	31251816	21	-	28162770	P31FUJ	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.5807255078346855	[195]	[153]	-5	hSpCas9	negative selection	11097407
31266859	31266882	21	-	28162770	OCIAML5	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.609381393371805	[64]	[178]	5	hSpCas9	negative selection	11266764
31251773	31251796	21	-	28162770	OCIAML5	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	1.1966072758716926	[50]	[210]	8	hSpCas9	negative selection	11266765
31252170	31252193	21	-	28162770	OCIAML5	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.8684109005136403	[43]	[144]	7	hSpCas9	negative selection	11266766
31266823	31266846	21	+	28162770	OCIAML5	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.8145918654453339	[75]	[77]	-5	hSpCas9	negative selection	11266767
31266582	31266605	21	-	28162770	OCIAML5	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.7757514088189564	[198]	[614]	6	hSpCas9	negative selection	11266768
31252024	31252047	21	-	28162770	OCIAML5	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.9833111041422498	[45]	[41]	-6	hSpCas9	negative selection	11266769
31252010	31252033	21	+	28162770	OCIAML5	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.015626137031872767	[193]	[353]	0	hSpCas9	negative selection	11266770
31251985	31252008	21	-	28162770	OCIAML5	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.4698615240233651	[61]	[154]	4	hSpCas9	negative selection	11266771
31251943	31251966	21	-	28162770	OCIAML5	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.44071517836384877	[39]	[97]	4	hSpCas9	negative selection	11266772
31251793	31251816	21	-	28162770	OCIAML5	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.33642513064674756	[134]	[192]	-2	hSpCas9	negative selection	11266773
31266859	31266882	21	-	28162770	EOL1	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.8051326046257639	[213]	[196]	7	hSpCas9	negative selection	11436130
31251773	31251796	21	-	28162770	EOL1	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	2.0861861618278863	[96]	[216]	9	hSpCas9	negative selection	11436131
31252170	31252193	21	-	28162770	EOL1	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.8460143690238452	[150]	[142]	7	hSpCas9	negative selection	11436132
31266823	31266846	21	+	28162770	EOL1	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.4651161529332372	[230]	[167]	4	hSpCas9	negative selection	11436133
31266582	31266605	21	-	28162770	EOL1	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.8456114331659312	[600]	[568]	7	hSpCas9	negative selection	11436134
31252024	31252047	21	-	28162770	EOL1	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.5969893490089879	[88]	[30]	-4	hSpCas9	negative selection	11436135
31252010	31252033	21	+	28162770	EOL1	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	-1.3411857838642147	[427]	[88]	-7	hSpCas9	negative selection	11436136
31251985	31252008	21	-	28162770	EOL1	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.6154437170407556	[139]	[112]	5	hSpCas9	negative selection	11436137
31251943	31251966	21	-	28162770	EOL1	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	-0.8578607933568387	[85]	[24]	-5	hSpCas9	negative selection	11436138
31251793	31251816	21	-	28162770	EOL1	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	0.1402764626259717	[154]	[89]	1	hSpCas9	negative selection	11436139
31266859	31266882	21	-	28162770	MOLM13	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	1.3037194722126602	[171]	[306]	8	hSpCas9	negative selection	11605496
31251773	31251796	21	-	28162770	MOLM13	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	1.3720293661370628	[139]	[261]	9	hSpCas9	negative selection	11605497
31252170	31252193	21	-	28162770	MOLM13	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	1.2069293039486435	[138]	[231]	8	hSpCas9	negative selection	11605498
31266823	31266846	21	+	28162770	MOLM13	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	0.20324212474248388	[178]	[148]	1	hSpCas9	negative selection	11605499
31266582	31266605	21	-	28162770	MOLM13	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.7239033597006005	[411]	[491]	5	hSpCas9	negative selection	11605500
31252024	31252047	21	-	28162770	MOLM13	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.599224814313958	[43]	[20]	-3	hSpCas9	negative selection	11605501
31252010	31252033	21	+	28162770	MOLM13	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	1.0631938264871943	[416]	[629]	7	hSpCas9	negative selection	11605502
31251985	31252008	21	-	28162770	MOLM13	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.3757090611128544	[130]	[72]	-2	hSpCas9	negative selection	11605503
31251943	31251966	21	-	28162770	MOLM13	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	-0.36218561701310925	[63]	[35]	-2	hSpCas9	negative selection	11605504
31251793	31251816	21	-	28162770	MOLM13	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.337294441471398	[331]	[189]	-2	hSpCas9	negative selection	11605505
31266859	31266882	21	-	28162770	HEL	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	-0.33273884886557414	[174]	[88]	-2	hSpCas9	negative selection	11774862
31251773	31251796	21	-	28162770	HEL	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	0.7384978148057878	[101]	[108]	6	hSpCas9	negative selection	11774863
31252170	31252193	21	-	28162770	HEL	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	-0.5846716641027154	[95]	[40]	-4	hSpCas9	negative selection	11774864
31266823	31266846	21	+	28162770	HEL	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.18733616655733076	[175]	[98]	-1	hSpCas9	negative selection	11774865
31266582	31266605	21	-	28162770	HEL	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	-0.3435862311025666	[419]	[211]	-2	hSpCas9	negative selection	11774866
31252024	31252047	21	-	28162770	HEL	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-1.9895293834991559	[61]	[9]	-8	hSpCas9	negative selection	11774867
31252010	31252033	21	+	28162770	HEL	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	-0.9459181522785409	[390]	[129]	-5	hSpCas9	negative selection	11774868
31251985	31252008	21	-	28162770	HEL	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	-0.8250401293504601	[129]	[46]	-5	hSpCas9	negative selection	11774869
31251943	31251966	21	-	28162770	HEL	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	-0.6096483296339281	[80]	[33]	-4	hSpCas9	negative selection	11774870
31251793	31251816	21	-	28162770	HEL	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-1.2317302859157842	[241]	[65]	-6	hSpCas9	negative selection	11774871
31266859	31266882	21	-	28162770	MV411	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.27638892447890445	[147]	[150]	2	hSpCas9	negative selection	11944228
31251773	31251796	21	-	28162770	MV411	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.2988444817743212	[91]	[62]	-2	hSpCas9	negative selection	11944229
31252170	31252193	21	-	28162770	MV411	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.954390575882542	[67]	[110]	8	hSpCas9	negative selection	11944230
31266823	31266846	21	+	28162770	MV411	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.17786828394989584	[93]	[69]	-1	hSpCas9	negative selection	11944231
31266582	31266605	21	-	28162770	MV411	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.8728349159031702	[257]	[397]	7	hSpCas9	negative selection	11944232
31252024	31252047	21	-	28162770	MV411	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-2.0983372860589546	[60]	[11]	-8	hSpCas9	negative selection	11944233
31252010	31252033	21	+	28162770	MV411	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.7117913681247986	[265]	[366]	6	hSpCas9	negative selection	11944234
31251985	31252008	21	-	28162770	MV411	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.3684529517441414	[79]	[86]	3	hSpCas9	negative selection	11944235
31251943	31251966	21	-	28162770	MV411	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	-0.21490566327442506	[61]	[44]	-2	hSpCas9	negative selection	11944236
31251793	31251816	21	-	28162770	MV411	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-1.3138736818737353	[120]	[40]	-7	hSpCas9	negative selection	11944237
31266859	31266882	21	-	28162770	MONOMAC1	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.9184403703603825	[89]	[194]	8	hSpCas9	negative selection	12113594
31251773	31251796	21	-	28162770	MONOMAC1	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	-0.36987344392176924	[61]	[54]	-3	hSpCas9	negative selection	12113595
31252170	31252193	21	-	28162770	MONOMAC1	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.7906848231620094	[58]	[116]	7	hSpCas9	negative selection	12113596
31266823	31266846	21	+	28162770	MONOMAC1	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.40348772452698	[89]	[77]	-3	hSpCas9	negative selection	12113597
31266582	31266605	21	-	28162770	MONOMAC1	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.7325738250490484	[230]	[439]	7	hSpCas9	negative selection	12113598
31252024	31252047	21	-	28162770	MONOMAC1	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.07839235056093452	[34]	[37]	0	hSpCas9	negative selection	12113599
31252010	31252033	21	+	28162770	MONOMAC1	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	1.632030330960545	[178]	[635]	9	hSpCas9	negative selection	12113600
31251985	31252008	21	-	28162770	MONOMAC1	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.13608945443267273	[76]	[96]	1	hSpCas9	negative selection	12113601
31251943	31251966	21	-	28162770	MONOMAC1	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.32379531624188695	[45]	[65]	3	hSpCas9	negative selection	12113602
31251793	31251816	21	-	28162770	MONOMAC1	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	0.31753632577020463	[48]	[69]	3	hSpCas9	negative selection	12113603
31266859	31266882	21	-	28162770	OCIAML2	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	1.3794747442747801	[18]	[273]	9	hSpCas9	negative selection	12282960
31251773	31251796	21	-	28162770	OCIAML2	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	1.3107298882824983	[11]	[164]	9	hSpCas9	negative selection	12282961
31252170	31252193	21	-	28162770	OCIAML2	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	0.8892661198442218	[14]	[153]	8	hSpCas9	negative selection	12282962
31266823	31266846	21	+	28162770	OCIAML2	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.2142900719823757	[17]	[85]	-2	hSpCas9	negative selection	12282963
31266582	31266605	21	-	28162770	OCIAML2	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	0.6218164235224339	[50]	[434]	6	hSpCas9	negative selection	12282964
31252024	31252047	21	-	28162770	OCIAML2	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	-0.8076648125197317	[17]	[56]	-5	hSpCas9	negative selection	12282965
31252010	31252033	21	+	28162770	OCIAML2	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.42844126590705806	[36]	[275]	4	hSpCas9	negative selection	12282966
31251985	31252008	21	-	28162770	OCIAML2	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.40383929267397983	[20]	[153]	4	hSpCas9	negative selection	12282967
31251943	31251966	21	-	28162770	OCIAML2	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.44690801456586593	[8]	[67]	4	hSpCas9	negative selection	12282968
31251793	31251816	21	-	28162770	OCIAML2	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	-0.08235923552610291	[16]	[88]	0	hSpCas9	negative selection	12282969
31266859	31266882	21	-	28162770	OCIAML3	viability	GCCTCTCGCACAAGACGCGGAGG	TIAM1	ENSG00000156299	0.4665339016108877	[34]	[145]	4	hSpCas9	negative selection	12452326
31251773	31251796	21	-	28162770	OCIAML3	viability	AGGTGGAGTCAGCCACCCGGAGG	TIAM1	ENSG00000156299	0.16680469579641077	[35]	[121]	1	hSpCas9	negative selection	12452327
31252170	31252193	21	-	28162770	OCIAML3	viability	AAGGATGTTAATGCAGGCGAGGG	TIAM1	ENSG00000156299	-0.8310468376250124	[32]	[55]	-6	hSpCas9	negative selection	12452328
31266823	31266846	21	+	28162770	OCIAML3	viability	CCTGTGGATCACCTTCCCCGAGG	TIAM1	ENSG00000156299	-0.3272210996292617	[31]	[76]	-3	hSpCas9	negative selection	12452329
31266582	31266605	21	-	28162770	OCIAML3	viability	GCAGAGCATGCCAGACACTGAGG	TIAM1	ENSG00000156299	1.0458167954315112	[85]	[535]	8	hSpCas9	negative selection	12452330
31252024	31252047	21	-	28162770	OCIAML3	viability	CAGCGGCAGCAGCTCCACCGGGG	TIAM1	ENSG00000156299	0.8433976719831353	[11]	[64]	7	hSpCas9	negative selection	12452331
31252010	31252033	21	+	28162770	OCIAML3	viability	CTGACGAGCCGCATCCCCGGTGG	TIAM1	ENSG00000156299	0.5142919750227257	[92]	[400]	5	hSpCas9	negative selection	12452332
31251985	31252008	21	-	28162770	OCIAML3	viability	GGTGTACGAGAACTTCCGGCGGG	TIAM1	ENSG00000156299	0.8947395451376899	[30]	[173]	7	hSpCas9	negative selection	12452333
31251943	31251966	21	-	28162770	OCIAML3	viability	CAACAGCGAGAGCCTGGAGGAGG	TIAM1	ENSG00000156299	0.751767196517567	[11]	[60]	6	hSpCas9	negative selection	12452334
31251793	31251816	21	-	28162770	OCIAML3	viability	GGTGCACAAGAAGAACAAGAAGG	TIAM1	ENSG00000156299	0.15601410666748938	[32]	[110]	1	hSpCas9	negative selection	12452335