Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 160418
• Symbol: TMTC3
• Description: transmembrane O-mannosyltransferase targeting cadherins 3

DataSource: http://genomecrispr.dkfz.de/#!/results/TMTC3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88190587	88190610	12	+	26472758	Jiyoye	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.19144669045043625	[143]	[123]	1	hSpCas9	negative selection	169354
88172703	88172726	12	+	26472758	Jiyoye	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.9363604252617826	[166]	[240]	6	hSpCas9	negative selection	169355
88160207	88160230	12	+	26472758	Jiyoye	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.15756149143440124	[427]	[359]	1	hSpCas9	negative selection	169356
88160703	88160726	12	+	26472758	Jiyoye	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.3708335344421533	[200]	[195]	2	hSpCas9	negative selection	169357
88176234	88176257	12	+	26472758	Jiyoye	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.7799846453954198	[77]	[100]	5	hSpCas9	negative selection	169358
88166339	88166362	12	-	26472758	Jiyoye	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	-0.0016301640614557744	[230]	[173]	0	hSpCas9	negative selection	169359
88166390	88166413	12	-	26472758	Jiyoye	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.7924969633304909	[146]	[63]	-5	hSpCas9	negative selection	169360
88166429	88166452	12	+	26472758	Jiyoye	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	-0.5119046231105594	[311]	[164]	-4	hSpCas9	negative selection	169361
88172688	88172711	12	-	26472758	Jiyoye	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	1.1901883431915161	[110]	[190]	7	hSpCas9	negative selection	169362
88148368	88148391	12	-	26472758	Jiyoye	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	1.18899521145634	[56]	[97]	7	hSpCas9	negative selection	169363
88190587	88190610	12	+	26472758	KBM7	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.26418022933376767	[429,434]	[253,237]	2	hSpCas9	negative selection	360472
88172703	88172726	12	+	26472758	KBM7	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.36184255829224066	[1045,1183]	[770,600]	4	hSpCas9	negative selection	360473
88160207	88160230	12	+	26472758	KBM7	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.37566386706864163	[1477,748]	[492,808]	4	hSpCas9	negative selection	360474
88160703	88160726	12	+	26472758	KBM7	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.33279480461531147	[735,382]	[260,376]	3	hSpCas9	negative selection	360475
88176234	88176257	12	+	26472758	KBM7	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.9386937200894527	[331,387]	[335,321]	8	hSpCas9	negative selection	360476
88166339	88166362	12	-	26472758	KBM7	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.7747066290472462	[614,453]	[473,381]	8	hSpCas9	negative selection	360477
88166390	88166413	12	-	26472758	KBM7	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.19638237766705458	[261,318]	[92,145]	-2	hSpCas9	negative selection	360478
88166429	88166452	12	+	26472758	KBM7	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.33737865277167345	[901,690]	[533,410]	3	hSpCas9	negative selection	360479
88172688	88172711	12	-	26472758	KBM7	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.5931078739514585	[557,507]	[423,336]	6	hSpCas9	negative selection	360480
88148368	88148391	12	-	26472758	KBM7	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.5724204682278904	[543,459]	[364,335]	6	hSpCas9	negative selection	360481
88190587	88190610	12	+	26472758	Raji	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.20791041132756394	[193]	[51]	2	hSpCas9	negative selection	551590
88172703	88172726	12	+	26472758	Raji	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.6532548654751749	[610]	[222]	6	hSpCas9	negative selection	551591
88160207	88160230	12	+	26472758	Raji	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.14933885181497786	[609]	[156]	1	hSpCas9	negative selection	551592
88160703	88160726	12	+	26472758	Raji	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.5544822438847418	[266]	[90]	5	hSpCas9	negative selection	551593
88176234	88176257	12	+	26472758	Raji	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.9698800116236648	[76]	[34]	8	hSpCas9	negative selection	551594
88166339	88166362	12	-	26472758	Raji	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.27673796332977635	[280]	[78]	2	hSpCas9	negative selection	551595
88166390	88166413	12	-	26472758	Raji	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.20456047094114094	[143]	[28]	-2	hSpCas9	negative selection	551596
88166429	88166452	12	+	26472758	Raji	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.13364919006740528	[380]	[96]	1	hSpCas9	negative selection	551597
88172688	88172711	12	-	26472758	Raji	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.787594351242572	[336]	[134]	7	hSpCas9	negative selection	551598
88148368	88148391	12	-	26472758	Raji	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	-0.027776047908036387	[245]	[55]	0	hSpCas9	negative selection	551599
88190587	88190610	12	+	26472758	K562	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	1.0826676576698349	[362]	[648]	8	hSpCas9	negative selection	742708
88172703	88172726	12	+	26472758	K562	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.025285502351892086	[957]	[822]	0	hSpCas9	negative selection	742709
88160207	88160230	12	+	26472758	K562	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.4405454943090894	[775]	[888]	3	hSpCas9	negative selection	742710
88160703	88160726	12	+	26472758	K562	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.4712782497461079	[403]	[245]	-3	hSpCas9	negative selection	742711
88176234	88176257	12	+	26472758	K562	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	-0.13760371438443386	[287]	[220]	-1	hSpCas9	negative selection	742712
88166339	88166362	12	-	26472758	K562	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.37845967511535045	[492]	[540]	3	hSpCas9	negative selection	742713
88166390	88166413	12	-	26472758	K562	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.244418727666447	[197]	[197]	1	hSpCas9	negative selection	742714
88166429	88166452	12	+	26472758	K562	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.9144533137136663	[449]	[715]	7	hSpCas9	negative selection	742715
88172688	88172711	12	-	26472758	K562	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.39142933716075734	[549]	[608]	3	hSpCas9	negative selection	742716
88148368	88148391	12	-	26472758	K562	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.8801009859954715	[353]	[549]	7	hSpCas9	negative selection	742717
88160208	88160231	12	+	26627737	DLD1	viability	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.1309496296897391	[405]	[186,78,146]	1	hSpCas9	negative selection	785773
88160708	88160731	12	+	26627737	DLD1	viability	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.7706989199602888	[664]	[321,356,380]	7	hSpCas9	negative selection	785774
88166390	88166413	12	-	26627737	DLD1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.6801237587644167	[564]	[325,278,248]	6	hSpCas9	negative selection	785775
88172648	88172671	12	-	26627737	DLD1	viability	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.7175070582656484	[618]	[302,326,323]	7	hSpCas9	negative selection	785776
88176298	88176321	12	+	26627737	DLD1	viability	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-1.0105508614610357	[606]	[138,96,52]	-7	hSpCas9	negative selection	785777
88190530	88190553	12	+	26627737	DLD1	viability	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.15343947642649974	[644]	[192,249,229]	1	hSpCas9	negative selection	785778
88160208	88160231	12	+	26627737	GBM cells	viability after 5 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.07193014607914892	[258]	[122,168]	1	hSpCas9	negative selection	868088
88160708	88160731	12	+	26627737	GBM cells	viability after 5 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.10702207021588572	[521]	[292,309]	1	hSpCas9	negative selection	868089
88166390	88166413	12	-	26627737	GBM cells	viability after 5 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.3463728518569069	[450]	[221,392]	5	hSpCas9	negative selection	868090
88172648	88172671	12	-	26627737	GBM cells	viability after 5 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.21435793620284904	[445]	[324,229]	3	hSpCas9	negative selection	868091
88176298	88176321	12	+	26627737	GBM cells	viability after 5 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.021232817425099686	[245]	[114,144]	0	hSpCas9	negative selection	868092
88190530	88190553	12	+	26627737	GBM cells	viability after 5 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.5180650617826686	[277]	[181,244]	7	hSpCas9	negative selection	868093
88160208	88160231	12	+	26627737	GBM cells	viability after 13 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.030877410477055937	[258]	[136,137]	0	hSpCas9	negative selection	950403
88160708	88160731	12	+	26627737	GBM cells	viability after 13 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.17741749926145967	[521]	[343,300]	2	hSpCas9	negative selection	950404
88166390	88166413	12	-	26627737	GBM cells	viability after 13 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.4639260534207603	[450]	[331,341]	6	hSpCas9	negative selection	950405
88172648	88172671	12	-	26627737	GBM cells	viability after 13 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.5121169212572435	[445]	[359,332]	6	hSpCas9	negative selection	950406
88176298	88176321	12	+	26627737	GBM cells	viability after 13 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.05140612649749376	[245]	[146,113]	0	hSpCas9	negative selection	950407
88190530	88190553	12	+	26627737	GBM cells	viability after 13 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.9549470401483005	[277]	[330,260]	9	hSpCas9	negative selection	950408
88160208	88160231	12	+	26627737	GBM cells	viability after 21 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.16528691402886442	[258]	[125,124]	-1	hSpCas9	negative selection	1032718
88160708	88160731	12	+	26627737	GBM cells	viability after 21 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.37497421668673314	[521]	[384,351]	4	hSpCas9	negative selection	1032719
88166390	88166413	12	-	26627737	GBM cells	viability after 21 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.44253176427364815	[450]	[356,310]	4	hSpCas9	negative selection	1032720
88172648	88172671	12	-	26627737	GBM cells	viability after 21 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.15881818352216903	[445]	[293,248]	1	hSpCas9	negative selection	1032721
88176298	88176321	12	+	26627737	GBM cells	viability after 21 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.15978914952359735	[245]	[153,144]	1	hSpCas9	negative selection	1032722
88190530	88190553	12	+	26627737	GBM cells	viability after 21 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	1.2067669691753355	[277]	[345,350]	9	hSpCas9	negative selection	1032723
88160208	88160231	12	+	26627737	RPE1	viability after 9 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	1.3100306908660881	[290]	[262,177]	7	hSpCas9	negative selection	1115033
88160708	88160731	12	+	26627737	RPE1	viability after 9 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.2534733133209073	[1485]	[561,544]	1	hSpCas9	negative selection	1115034
88166390	88166413	12	-	26627737	RPE1	viability after 9 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.3594094376059628	[1295]	[344,746]	2	hSpCas9	negative selection	1115035
88172648	88172671	12	-	26627737	RPE1	viability after 9 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.2529976407471881	[1618]	[610,594]	1	hSpCas9	negative selection	1115036
88176298	88176321	12	+	26627737	RPE1	viability after 9 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.19751549901445298	[830]	[256,187]	-1	hSpCas9	negative selection	1115037
88190530	88190553	12	+	26627737	RPE1	viability after 9 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	2.470616960451884	[316]	[622,455]	9	hSpCas9	negative selection	1115038
88160208	88160231	12	+	26627737	RPE1	viability after 12 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	1.3305652285568685	[290]	[200,191]	7	hSpCas9	negative selection	1197348
88160708	88160731	12	+	26627737	RPE1	viability after 12 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.5518198379384693	[1485]	[593,575]	3	hSpCas9	negative selection	1197349
88166390	88166413	12	-	26627737	RPE1	viability after 12 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.02733311259623905	[1295]	[363,317]	0	hSpCas9	negative selection	1197350
88172648	88172671	12	-	26627737	RPE1	viability after 12 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3693570519828213	[1618]	[438,691]	2	hSpCas9	negative selection	1197351
88176298	88176321	12	+	26627737	RPE1	viability after 12 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.19305277456030528	[830]	[177,336]	1	hSpCas9	negative selection	1197352
88190530	88190553	12	+	26627737	RPE1	viability after 12 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	2.819267877982946	[316]	[536,668]	9	hSpCas9	negative selection	1197353
88160208	88160231	12	+	26627737	RPE1	viability after 15 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.7891698460397931	[290]	[99,182]	5	hSpCas9	negative selection	1279663
88160708	88160731	12	+	26627737	RPE1	viability after 15 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.6361792663406602	[1485]	[803,507]	4	hSpCas9	negative selection	1279664
88166390	88166413	12	-	26627737	RPE1	viability after 15 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.1780403254110452	[1295]	[399,428]	1	hSpCas9	negative selection	1279665
88172648	88172671	12	-	26627737	RPE1	viability after 15 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3128136958640102	[1618]	[519,615]	2	hSpCas9	negative selection	1279666
88176298	88176321	12	+	26627737	RPE1	viability after 15 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.05733547614256641	[830]	[266,222]	0	hSpCas9	negative selection	1279667
88190530	88190553	12	+	26627737	RPE1	viability after 15 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	2.673999997923051	[316]	[724,424]	9	hSpCas9	negative selection	1279668
88160208	88160231	12	+	26627737	RPE1	viability after 18 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	1.2700709975380555	[290]	[200,176]	7	hSpCas9	negative selection	1361978
88160708	88160731	12	+	26627737	RPE1	viability after 18 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.31899973178569274	[1485]	[507,491]	2	hSpCas9	negative selection	1361979
88166390	88166413	12	-	26627737	RPE1	viability after 18 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.1785531599661796	[1295]	[317,478]	1	hSpCas9	negative selection	1361980
88172648	88172671	12	-	26627737	RPE1	viability after 18 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3262764603063457	[1618]	[468,631]	2	hSpCas9	negative selection	1361981
88176298	88176321	12	+	26627737	RPE1	viability after 18 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.2199170895675736	[830]	[222,301]	1	hSpCas9	negative selection	1361982
88190530	88190553	12	+	26627737	RPE1	viability after 18 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	2.3998584032339876	[316]	[450,451]	9	hSpCas9	negative selection	1361983
88160208	88160231	12	+	26627737	HeLa	viability after 8 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.8981093282376367	[192]	[194,170,114]	7	hSpCas9	negative selection	1444293
88160708	88160731	12	+	26627737	HeLa	viability after 8 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.6899100950776782	[612]	[465,509,329]	6	hSpCas9	negative selection	1444294
88166390	88166413	12	-	26627737	HeLa	viability after 8 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.5104845554421156	[644]	[199,109,275]	-5	hSpCas9	negative selection	1444295
88172648	88172671	12	-	26627737	HeLa	viability after 8 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.14227863738076862	[591]	[340,278,247]	1	hSpCas9	negative selection	1444296
88176298	88176321	12	+	26627737	HeLa	viability after 8 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.2226714782656244	[723]	[362,383,95]	-2	hSpCas9	negative selection	1444297
88190530	88190553	12	+	26627737	HeLa	viability after 8 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.6263756009086203	[527]	[453,397,241]	5	hSpCas9	negative selection	1444298
88160208	88160231	12	+	26627737	HeLa	viability after 12 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.9478153947476784	[192]	[189,102,174]	7	hSpCas9	negative selection	1526608
88160708	88160731	12	+	26627737	HeLa	viability after 12 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.7914474567086434	[612]	[678,328,325]	6	hSpCas9	negative selection	1526609
88166390	88166413	12	-	26627737	HeLa	viability after 12 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.47436187057984674	[644]	[259,83,244]	-4	hSpCas9	negative selection	1526610
88172648	88172671	12	-	26627737	HeLa	viability after 12 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.43523533572204187	[591]	[377,290,328]	4	hSpCas9	negative selection	1526611
88176298	88176321	12	+	26627737	HeLa	viability after 12 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.6245198383424627	[723]	[335,102,156]	-5	hSpCas9	negative selection	1526612
88190530	88190553	12	+	26627737	HeLa	viability after 12 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.37991480632266283	[527]	[350,177,335]	3	hSpCas9	negative selection	1526613
88160208	88160231	12	+	26627737	HeLa	viability after 15 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	1.1374405980425135	[192]	[112,188,220]	7	hSpCas9	negative selection	1608923
88160708	88160731	12	+	26627737	HeLa	viability after 15 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.8381520492472179	[612]	[421,551,357]	6	hSpCas9	negative selection	1608924
88166390	88166413	12	-	26627737	HeLa	viability after 15 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.4979923140254518	[644]	[159,92,314]	-4	hSpCas9	negative selection	1608925
88172648	88172671	12	-	26627737	HeLa	viability after 15 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8468445890994077	[591]	[634,262,396]	6	hSpCas9	negative selection	1608926
88176298	88176321	12	+	26627737	HeLa	viability after 15 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.5046154001837047	[723]	[319,151,144]	-4	hSpCas9	negative selection	1608927
88190530	88190553	12	+	26627737	HeLa	viability after 15 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.127969066479371	[527]	[333,114,255]	1	hSpCas9	negative selection	1608928
88160208	88160231	12	+	26627737	HeLa	viability after 18 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	1.098221501380434	[192]	[67,154,220]	7	hSpCas9	negative selection	1691238
88160708	88160731	12	+	26627737	HeLa	viability after 18 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.8129898671740359	[612]	[264,460,357]	6	hSpCas9	negative selection	1691239
88166390	88166413	12	-	26627737	HeLa	viability after 18 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.4803886058206403	[644]	[106,82,314]	-4	hSpCas9	negative selection	1691240
88172648	88172671	12	-	26627737	HeLa	viability after 18 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8487578807112347	[591]	[434,207,396]	6	hSpCas9	negative selection	1691241
88176298	88176321	12	+	26627737	HeLa	viability after 18 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-0.4953542394770182	[723]	[221,119,144]	-4	hSpCas9	negative selection	1691242
88190530	88190553	12	+	26627737	HeLa	viability after 18 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.09900410152310735	[527]	[219,88,255]	0	hSpCas9	negative selection	1691243
88160208	88160231	12	+	26627737	HCT116	viability after 6 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-1.004976978783346	[1061]	[146,47]	-5	hSpCas9	negative selection	1773553
88160708	88160731	12	+	26627737	HCT116	viability after 6 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.7657075499537604	[1465]	[289,447]	4	hSpCas9	negative selection	1773554
88166390	88166413	12	-	26627737	HCT116	viability after 6 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	2.0338829146669744	[377]	[165,285]	8	hSpCas9	negative selection	1773555
88172648	88172671	12	-	26627737	HCT116	viability after 6 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	-0.5281056034791656	[731]	[73,82]	-3	hSpCas9	negative selection	1773556
88176298	88176321	12	+	26627737	HCT116	viability after 6 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	1.1072141643591238	[517]	[255,130]	6	hSpCas9	negative selection	1773557
88190530	88190553	12	+	26627737	HCT116	viability after 6 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	2.154916536900252	[480]	[348,329]	9	hSpCas9	negative selection	1773558
88160208	88160231	12	+	26627737	HCT116	viability after 8 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.24531573281610844	[223]	[148,145,143]	2	hSpCas9	negative selection	1855868
88160708	88160731	12	+	26627737	HCT116	viability after 8 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	-0.6878151448097976	[988]	[310,410,292]	-7	hSpCas9	negative selection	1855869
88166390	88166413	12	-	26627737	HCT116	viability after 8 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.07128654435537873	[448]	[283,214,280]	0	hSpCas9	negative selection	1855870
88172648	88172671	12	-	26627737	HCT116	viability after 8 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.24548563063946982	[544]	[343,381,341]	2	hSpCas9	negative selection	1855871
88176298	88176321	12	+	26627737	HCT116	viability after 8 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	2.28303353188159	[88]	[181,290,241]	9	hSpCas9	negative selection	1855872
88190530	88190553	12	+	26627737	HCT116	viability after 8 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.6910514194136153	[366]	[309,328,339]	6	hSpCas9	negative selection	1855873
88160208	88160231	12	+	26627737	HCT116	viability after 9 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.6276941039032573	[1061]	[311,81]	-4	hSpCas9	negative selection	1938183
88160708	88160731	12	+	26627737	HCT116	viability after 9 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.32740249856212267	[1465]	[541,450]	2	hSpCas9	negative selection	1938184
88166390	88166413	12	-	26627737	HCT116	viability after 9 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	1.9624882000564308	[377]	[303,463]	9	hSpCas9	negative selection	1938185
88172648	88172671	12	-	26627737	HCT116	viability after 9 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	-0.558754029319072	[731]	[106,152]	-4	hSpCas9	negative selection	1938186
88176298	88176321	12	+	26627737	HCT116	viability after 9 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.040032297517156035	[517]	[144,139]	0	hSpCas9	negative selection	1938187
88190530	88190553	12	+	26627737	HCT116	viability after 9 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.3502692247498494	[480]	[213,123]	2	hSpCas9	negative selection	1938188
88160208	88160231	12	+	26627737	HCT116	viability after 12 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.6720497905881184	[223]	[63,93,64]	-6	hSpCas9	negative selection	2020498
88160708	88160731	12	+	26627737	HCT116	viability after 12 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	-0.5758924553814375	[988]	[217,491,350]	-6	hSpCas9	negative selection	2020499
88166390	88166413	12	-	26627737	HCT116	viability after 12 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.26350291512307933	[448]	[206,204,176]	-3	hSpCas9	negative selection	2020500
88172648	88172671	12	-	26627737	HCT116	viability after 12 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.2034000166981852	[544]	[356,290,337]	2	hSpCas9	negative selection	2020501
88176298	88176321	12	+	26627737	HCT116	viability after 12 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	2.1138640846106136	[88]	[242,210,149]	9	hSpCas9	negative selection	2020502
88190530	88190553	12	+	26627737	HCT116	viability after 12 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.5204507585708813	[366]	[210,411,215]	5	hSpCas9	negative selection	2020503
88160208	88160231	12	+	26627737	HCT116	viability after 15 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.23501490641368972	[223]	[64,104,151]	-2	hSpCas9	negative selection	2102813
88160708	88160731	12	+	26627737	HCT116	viability after 15 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	-0.6277069302285407	[988]	[253,386,446]	-6	hSpCas9	negative selection	2102814
88166390	88166413	12	-	26627737	HCT116	viability after 15 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.16236588649976802	[448]	[207,124,353]	-2	hSpCas9	negative selection	2102815
88172648	88172671	12	-	26627737	HCT116	viability after 15 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.45947293880870654	[544]	[606,306,398]	4	hSpCas9	negative selection	2102816
88176298	88176321	12	+	26627737	HCT116	viability after 15 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	2.2749008560575903	[88]	[270,228,244]	9	hSpCas9	negative selection	2102817
88190530	88190553	12	+	26627737	HCT116	viability after 15 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.8323872319514063	[366]	[386,338,400]	7	hSpCas9	negative selection	2102818
88160208	88160231	12	+	26627737	HCT116	viability after 18 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.12162769053932726	[223]	[111,106,135]	1	hSpCas9	negative selection	2185128
88160708	88160731	12	+	26627737	HCT116	viability after 18 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	-0.6369561459166952	[988]	[208,282,437]	-5	hSpCas9	negative selection	2185129
88166390	88166413	12	-	26627737	HCT116	viability after 18 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.11126512926205673	[448]	[142,197,264]	-1	hSpCas9	negative selection	2185130
88172648	88172671	12	-	26627737	HCT116	viability after 18 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3749258947265727	[544]	[328,329,367]	3	hSpCas9	negative selection	2185131
88176298	88176321	12	+	26627737	HCT116	viability after 18 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	2.310356587133886	[88]	[288,175,175]	9	hSpCas9	negative selection	2185132
88190530	88190553	12	+	26627737	HCT116	viability after 18 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.7100031067305534	[366]	[197,513,136]	6	hSpCas9	negative selection	2185133
88155952	88155975	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATACAAAAATTAGCCAGGCGTAG	TMTC3	ENSG00000139324	0.7667043826941231	[92,346]	[53,113]	3	dCas9-VP64	positive selection	2426037
88142387	88142410	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCATGGTCTACCTCGTTCAGG	TMTC3	ENSG00000139324	1.5495899192339941	[340,115]	[25,274]	6	dCas9-VP64	positive selection	2456960
88142341	88142364	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGAGAGGCGGGAGGAGCAGCGG	TMTC3	ENSG00000139324	5.26879492800513	[3,17]	[162,25]	9	dCas9-VP64	positive selection	2456961
88142364	88142387	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGCGCCTGCAAACTGGTGG	TMTC3	ENSG00000139324	1.0801813570018801	[8,47]	[3,22]	4	dCas9-VP64	positive selection	2456962
88155952	88155975	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATACAAAAATTAGCCAGGCGTAG	TMTC3	ENSG00000139324	0.15255249232697954	[139,139]	[73,28]	1	dCas9-VP64	positive selection	2521292
88142387	88142410	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCATGGTCTACCTCGTTCAGG	TMTC3	ENSG00000139324	-0.7299988024394414	[329,327]	[67,60]	-7	dCas9-VP64	positive selection	2552215
88142341	88142364	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGAGAGGCGGGAGGAGCAGCGG	TMTC3	ENSG00000139324	0.712249199349815	[78,63]	[52,23]	5	dCas9-VP64	positive selection	2552216
88142364	88142387	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGCGCCTGCAAACTGGTGG	TMTC3	ENSG00000139324	-0.13006333121058855	[26,57]	[10,13]	-1	dCas9-VP64	positive selection	2552217
88160704	88160727	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.19202393660077088	[4,4]	[3,4]	4	hSpCas9	positive selection	3028218
88160208	88160231	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	-0.2584227270674887	[3,3]	[2,2]	-4	hSpCas9	positive selection	3028219
88160688	88160711	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	0.5263617263242727	[3,3]	[1,6]	9	hSpCas9	positive selection	3028220
88172667	88172690	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	-0.5241306459148175	[3,3]	[3,0]	-6	hSpCas9	positive selection	3028221
88160704	88160727	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.25974958560376327	[4,4]	[3,1]	-4	hSpCas9	positive selection	3096076
88160208	88160231	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	-0.18317124117582403	[3,3]	[4,0]	-3	hSpCas9	positive selection	3096077
88160688	88160711	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	-0.3649548389824634	[3,3]	[2,0]	-5	hSpCas9	positive selection	3096078
88172667	88172690	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	-0.05592993080046278	[3,3]	[3,1]	-1	hSpCas9	positive selection	3096079
88153316	88153339		-	24336571	A375	resistance to PLX after 7 days	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	-0.24887194944600788	[6,7]	[5,5]	-7	hSpCas9	positive selection	3151651
88154282	88154305		+	24336571	A375	resistance to PLX after 7 days	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.028501424158427158	[28,29]	[28,27]	-1	hSpCas9	positive selection	3151652
88153316	88153339		-	24336571	A375	resistance to PLX after 14 days	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	1.4101115976374117	[4,5]	[4,7]	8	hSpCas9	positive selection	3209444
88154282	88154305		+	24336571	A375	resistance to PLX after 14 days	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.08339139753772229	[32,24]	[14,12]	0	hSpCas9	positive selection	3209445
88153316	88153339		-	24336571	A375	viability after 7 days	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	-0.0757048152843025	[7]	[6,7]	-1	hSpCas9	negative selection	3267237
88154282	88154305		+	24336571	A375	viability after 7 days	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.21133695783512496	[25]	[28,29]	3	hSpCas9	negative selection	3267238
88153316	88153339		-	24336571	A375	viability after 14 days	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	-0.5558463935079068	[7]	[4,5]	-6	hSpCas9	negative selection	3325030
88154282	88154305		+	24336571	A375	viability after 14 days	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.23156349806203358	[25]	[32,24]	3	hSpCas9	negative selection	3325031
88160129	88160152	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.46291034509572904	[110,110]	[0,0]	2	hSpCas9	positive selection	3398264
88153316	88153339	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3398265
88160205	88160228	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-1.0418818069414437	[314,314]	[0,0]	-7	hSpCas9	positive selection	3398266
88160703	88160726	12	+	26780180	HT29	viability (Avana library 4 designs)	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.40743937217151	[]	[]	1	hSpCas9	negative selection	3467012
88160207	88160230	12	+	26780180	HT29	viability (Avana library 4 designs)	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.978473793791763	[]	[]	4	hSpCas9	negative selection	3467013
88160688	88160711	12	-	26780180	HT29	viability (Avana library 4 designs)	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	0.773963711700281	[]	[]	3	hSpCas9	negative selection	3467014
88172667	88172690	12	-	26780180	HT29	viability (Avana library 4 designs)	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	0.0885909945180795	[]	[]	0	hSpCas9	negative selection	3467015
88160703	88160726	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.215970663511038	[]	[]	0	hSpCas9	negative selection	3570961
88160688	88160711	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	-1.5369694457667	[]	[]	-2	hSpCas9	negative selection	3570962
88160207	88160230	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	2.20523864548304	[]	[]	3	hSpCas9	negative selection	3570963
88172667	88172690	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	-7.51895395930993	[]	[]	-7	hSpCas9	negative selection	3570964
88153311	88153334	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTCAATACTGTTAAGGGACGG	TMTC3	ENSG00000139324	-2.273111285096	[]	[]	-3	hSpCas9	negative selection	3570965
88160709	88160732	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGTTTCTCCGTGGAAAGGG	TMTC3	ENSG00000139324	4.05646562307193	[]	[]	6	hSpCas9	negative selection	3570966
88160703	88160726	12	+	26780180	A375	viability (Avana lentiGuide)	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.0750169145769072	[]	[]	0	hSpCas9	negative selection	3679620
88160688	88160711	12	-	26780180	A375	viability (Avana lentiGuide)	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	0.333064976598941	[]	[]	0	hSpCas9	negative selection	3679621
88160207	88160230	12	+	26780180	A375	viability (Avana lentiGuide)	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	-0.487260388734327	[]	[]	0	hSpCas9	negative selection	3679622
88172667	88172690	12	-	26780180	A375	viability (Avana lentiGuide)	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	5.18981765269617	[]	[]	4	hSpCas9	negative selection	3679623
88153311	88153334	12	-	26780180	A375	viability (Avana lentiGuide)	ATGTCAATACTGTTAAGGGACGG	TMTC3	ENSG00000139324	-3.18667758323066	[]	[]	-5	hSpCas9	negative selection	3679624
88160709	88160732	12	+	26780180	A375	viability (Avana lentiGuide)	GGACAGTTTCTCCGTGGAAAGGG	TMTC3	ENSG00000139324	1.42156905592492	[]	[]	1	hSpCas9	negative selection	3679625
88160703	88160726	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.020551351514054877	[6]	[6,5]	0	hSpCas9	positive selection	3788227
88160688	88160711	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	-0.1995118861778889	[5]	[4,3]	-3	hSpCas9	positive selection	3788228
88160207	88160230	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.09890197710371885	[5]	[6,4]	2	hSpCas9	positive selection	3788229
88172667	88172690	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	-0.1406286580224305	[5]	[4,5]	-2	hSpCas9	positive selection	3788230
88153311	88153334	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTCAATACTGTTAAGGGACGG	TMTC3	ENSG00000139324	-0.34914228909813527	[7]	[5,5]	-5	hSpCas9	positive selection	3788231
88160709	88160732	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGTTTCTCCGTGGAAAGGG	TMTC3	ENSG00000139324	0.1112583773563687	[4]	[5,5]	3	hSpCas9	positive selection	3788232
88160703	88160726	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.1836221166507453	[6]	[6,6]	4	hSpCas9	positive selection	3896834
88160688	88160711	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCAGTAGTACATAGTAATGG	TMTC3	ENSG00000139324	-0.47524374756466403	[4]	[2,2]	-6	hSpCas9	positive selection	3896835
88160207	88160230	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.24892521169670023	[5]	[5,5]	6	hSpCas9	positive selection	3896836
88172667	88172690	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAACATATAATACTCGCTCGG	TMTC3	ENSG00000139324	0.1159625215901742	[5]	[4,4]	2	hSpCas9	positive selection	3896837
88153311	88153334	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTCAATACTGTTAAGGGACGG	TMTC3	ENSG00000139324	0.17257172348834882	[5]	[5,5]	4	hSpCas9	positive selection	3896838
88160709	88160732	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGTTTCTCCGTGGAAAGGG	TMTC3	ENSG00000139324	0.05218134314484598	[5]	[4,4]	1	hSpCas9	positive selection	3896839
88160129	88160152	12	-	26780180	A375	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	1.53344576291412	[]	[]	8	hSpCas9	negative selection	4006197
88153383	88153406	12	-	26780180	A375	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.742698305479693	[]	[]	2	hSpCas9	negative selection	4006198
88154372	88154395	12	-	26780180	A375	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	1.0753917758803	[]	[]	5	hSpCas9	negative selection	4006199
88153316	88153339	12	-	26780180	A375	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.715163550842763	[]	[]	2	hSpCas9	negative selection	4006200
88160205	88160228	12	+	26780180	A375	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	1.89390069148606	[]	[]	9	hSpCas9	negative selection	4006201
88154282	88154305	12	+	26780180	A375	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.69435597146118	[]	[]	2	hSpCas9	negative selection	4006202
88160129	88160152	12	-	26780180	HT29	viability (GeCKOv2 library)	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	1.7306015247272	[]	[]	8	hSpCas9	negative selection	4114163
88153383	88153406	12	-	26780180	HT29	viability (GeCKOv2 library)	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.179883429984927	[]	[]	0	hSpCas9	negative selection	4114164
88154372	88154395	12	-	26780180	HT29	viability (GeCKOv2 library)	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	1.68848289896686	[]	[]	8	hSpCas9	negative selection	4114165
88153316	88153339	12	-	26780180	HT29	viability (GeCKOv2 library)	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.782968813974557	[]	[]	3	hSpCas9	negative selection	4114166
88160205	88160228	12	+	26780180	HT29	viability (GeCKOv2 library)	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	2.02963566399053	[]	[]	9	hSpCas9	negative selection	4114167
88154282	88154305	12	+	26780180	HT29	viability (GeCKOv2 library)	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.147800572899035	[]	[]	-4	hSpCas9	negative selection	4114168
88153316	88153339	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.14807897214254248	[2]	[1,2]	4	hSpCas9	positive selection	4178168
88154282	88154305	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.24648653480877128	[4]	[3,3]	6	hSpCas9	positive selection	4178169
88153316	88153339	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	1.586598232992856	[2]	[1,0,4,3]	9	hSpCas9	positive selection	4242190
88154282	88154305	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.8014842775435012	[3]	[2,1,0,3]	5	hSpCas9	positive selection	4242191
88154282	88154305	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.16312647686526713	[3]	[3,2]	3	hSpCas9	positive selection	4304297
88154372	88154395	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	-0.37413200489915754	[3]	[2,1]	-7	hSpCas9	positive selection	4304298
88153383	88153406	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.14566768005639685	[1]	[3,0]	3	hSpCas9	positive selection	4304299
88160129	88160152	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.006702348996415752	[2]	[1,1]	0	hSpCas9	positive selection	4368547
88153316	88153339	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.2553825251582855	[2]	[2,1]	5	hSpCas9	positive selection	4368548
88160205	88160228	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.3521707931039678	[3]	[2,1]	-6	hSpCas9	positive selection	4368549
88148491	88148513	12	-	27760321	OCIAML3	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.45387551014332894	[44,35]	[43,41]	5	hSpCas9	negative selection	4448787
88160689	88160711	12	+	27760321	OCIAML3	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-1.4458533115021437	[74,67]	[13,28]	-8	hSpCas9	negative selection	4448788
88166355	88166377	12	-	27760321	OCIAML3	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.8331837174559258	[377,311]	[448,516]	8	hSpCas9	negative selection	4448789
88166460	88166482	12	-	27760321	OCIAML3	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-2.755895085886417	[20,4]	[0,1]	-9	hSpCas9	negative selection	4448790
88172648	88172670	12	-	27760321	OCIAML3	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.18325867706461563	[129,123]	[95,134]	2	hSpCas9	negative selection	4448791
88148491	88148513	12	-	27760321	OCIAML2	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.6830401877830861	[44,35]	[50,53]	8	hSpCas9	negative selection	4532250
88160689	88160711	12	+	27760321	OCIAML2	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-0.24473674304289617	[74,67]	[59,33]	-3	hSpCas9	negative selection	4532251
88166355	88166377	12	-	27760321	OCIAML2	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.24141947850173384	[377,311]	[349,299]	3	hSpCas9	negative selection	4532252
88166460	88166482	12	-	27760321	OCIAML2	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	0.20734202586065376	[20,4]	[11,10]	2	hSpCas9	negative selection	4532253
88172648	88172670	12	-	27760321	OCIAML2	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3993445725940048	[129,123]	[139,129]	5	hSpCas9	negative selection	4532254
88148491	88148513	12	-	27760321	MV411	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.3798118613487458	[44,35]	[0,84]	2	hSpCas9	negative selection	4615713
88160689	88160711	12	+	27760321	MV411	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	1.4324686352296032	[74,67]	[195,23]	9	hSpCas9	negative selection	4615714
88166355	88166377	12	-	27760321	MV411	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.7705053292912167	[377,311]	[137,759]	5	hSpCas9	negative selection	4615715
88166460	88166482	12	-	27760321	MV411	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-1.1058418585138545	[20,4]	[0,7]	-6	hSpCas9	negative selection	4615716
88172648	88172670	12	-	27760321	MV411	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.09440688642966388	[129,123]	[83,97]	0	hSpCas9	negative selection	4615717
88148491	88148513	12	-	27760321	HL60	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.6420317654577405	[44,35]	[28,74]	7	hSpCas9	negative selection	4699176
88160689	88160711	12	+	27760321	HL60	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-0.3375482192113073	[74,67]	[68,21]	-4	hSpCas9	negative selection	4699177
88166355	88166377	12	-	27760321	HL60	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.7751029467639661	[377,311]	[515,441]	8	hSpCas9	negative selection	4699178
88166460	88166482	12	-	27760321	HL60	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-3.338829711392213	[20,4]	[0,0]	-9	hSpCas9	negative selection	4699179
88172648	88172670	12	-	27760321	HL60	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.4288714709307524	[129,123]	[84,197]	5	hSpCas9	negative selection	4699180
88148491	88148513	12	-	27760321	HT1080	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.021198908322656695	[35,27]	[0,25]	0	hSpCas9	negative selection	4782639
88160689	88160711	12	+	27760321	HT1080	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-1.7286178107982768	[67,52]	[12,0]	-6	hSpCas9	negative selection	4782640
88166355	88166377	12	-	27760321	HT1080	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	1.461854282927722	[311,243]	[85,544]	7	hSpCas9	negative selection	4782641
88166460	88166482	12	-	27760321	HT1080	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4782642
88172648	88172670	12	-	27760321	HT1080	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	-0.26421331347217447	[123,96]	[39,32]	-1	hSpCas9	negative selection	4782643
88148491	88148513	12	-	27760321	HT29	viability after 7 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-1.1101475436935022	[35,27]	[25,8,22]	-8	hSpCas9	negative selection	4866102
88160689	88160711	12	+	27760321	HT29	viability after 7 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-2.0766730339926904	[67,52]	[16,16,20]	-9	hSpCas9	negative selection	4866103
88166355	88166377	12	-	27760321	HT29	viability after 7 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.6059310156913372	[311,243]	[653,732,268]	8	hSpCas9	negative selection	4866104
88166460	88166482	12	-	27760321	HT29	viability after 7 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	1.2941035355369737	[4,3]	[41,3,0]	9	hSpCas9	negative selection	4866105
88172648	88172670	12	-	27760321	HT29	viability after 7 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.03883779529260534	[123,96]	[155,164,118]	0	hSpCas9	negative selection	4866106
88148491	88148513	12	-	27760321	HT29	viability after 25 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-1.5052229013946725	[35,27]	[18,16,0]	-7	hSpCas9	negative selection	4949565
88160689	88160711	12	+	27760321	HT29	viability after 25 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-0.021437888673595307	[67,52]	[60,115,22]	0	hSpCas9	negative selection	4949566
88166355	88166377	12	-	27760321	HT29	viability after 25 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.2536726185407671	[311,243]	[303,376,468]	2	hSpCas9	negative selection	4949567
88166460	88166482	12	-	27760321	HT29	viability after 25 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-0.046073990605024484	[4,3]	[5,2,5]	0	hSpCas9	negative selection	4949568
88172648	88172670	12	-	27760321	HT29	viability after 25 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8502441036881017	[123,96]	[190,171,332]	8	hSpCas9	negative selection	4949569
88148491	88148513	12	-	27760321	HT29	viability after 22 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-1.530313357277322	[35,27]	[24,8,3]	-7	hSpCas9	negative selection	5033028
88160689	88160711	12	+	27760321	HT29	viability after 22 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-2.918423647052261	[67,52]	[0,14,11]	-8	hSpCas9	negative selection	5033029
88166355	88166377	12	-	27760321	HT29	viability after 22 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.16264465139339357	[311,243]	[333,283,462]	1	hSpCas9	negative selection	5033030
88166460	88166482	12	-	27760321	HT29	viability after 22 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	3.708815184188249	[4,3]	[147,8,44]	9	hSpCas9	negative selection	5033031
88172648	88172670	12	-	27760321	HT29	viability after 22 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.6341893309037383	[123,96]	[107,114,375]	7	hSpCas9	negative selection	5033032
88148491	88148513	12	-	27760321	HT29	viability after 19 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-0.14350376794539876	[35,27]	[13,13,67]	-1	hSpCas9	negative selection	5116491
88160689	88160711	12	+	27760321	HT29	viability after 19 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-0.9413596068261163	[67,52]	[12,65,26]	-6	hSpCas9	negative selection	5116492
88166355	88166377	12	-	27760321	HT29	viability after 19 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.4364641402453706	[311,243]	[508,254,530]	4	hSpCas9	negative selection	5116493
88166460	88166482	12	-	27760321	HT29	viability after 19 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-1.9423603243560912	[4,3]	[0,1,0]	-8	hSpCas9	negative selection	5116494
88172648	88172670	12	-	27760321	HT29	viability after 19 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.18623361844475794	[123,96]	[160,97,172]	1	hSpCas9	negative selection	5116495
88148491	88148513	12	-	27760321	HT29	viability after 16 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-0.5623323816662893	[35,27]	[56,16,1]	-5	hSpCas9	negative selection	5199954
88160689	88160711	12	+	27760321	HT29	viability after 16 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-1.5621632033287658	[67,52]	[34,18,15]	-8	hSpCas9	negative selection	5199955
88166355	88166377	12	-	27760321	HT29	viability after 16 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.2940751510654281	[311,243]	[302,370,462]	3	hSpCas9	negative selection	5199956
88166460	88166482	12	-	27760321	HT29	viability after 16 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	1.7204366889116214	[4,3]	[26,9,13]	9	hSpCas9	negative selection	5199957
88172648	88172670	12	-	27760321	HT29	viability after 16 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8354933529440569	[123,96]	[205,239,213]	8	hSpCas9	negative selection	5199958
88148491	88148513	12	-	27760321	HT29	viability after 13 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.9329293584159424	[35,27]	[119,30,61]	9	hSpCas9	negative selection	5283417
88160689	88160711	12	+	27760321	HT29	viability after 13 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-0.3347799472629003	[67,52]	[120,10,35]	-4	hSpCas9	negative selection	5283418
88166355	88166377	12	-	27760321	HT29	viability after 13 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	0.05411918883871525	[311,243]	[364,278,358]	0	hSpCas9	negative selection	5283419
88166460	88166482	12	-	27760321	HT29	viability after 13 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	0.44521493945118085	[4,3]	[1,5,12]	5	hSpCas9	negative selection	5283420
88172648	88172670	12	-	27760321	HT29	viability after 13 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	-0.14526868665094517	[123,96]	[121,79,143]	-2	hSpCas9	negative selection	5283421
88148491	88148513	12	-	27760321	HT29	viability after 10 days	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	0.18762550744822848	[35,27]	[78,0,54]	2	hSpCas9	negative selection	5366880
88160689	88160711	12	+	27760321	HT29	viability after 10 days	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-1.3802849624810234	[67,52]	[15,13,55]	-8	hSpCas9	negative selection	5366881
88166355	88166377	12	-	27760321	HT29	viability after 10 days	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	-0.08574129907840483	[311,243]	[408,364,210]	-1	hSpCas9	negative selection	5366882
88166460	88166482	12	-	27760321	HT29	viability after 10 days	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	1.0401493990678397	[4,3]	[0,1,30]	9	hSpCas9	negative selection	5366883
88172648	88172670	12	-	27760321	HT29	viability after 10 days	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.7233651528825582	[123,96]	[145,195,337]	8	hSpCas9	negative selection	5366884
88148491	88148513	12	-	27760321	MOLM13	viability	TTACTTACCTCAGACATAGGGG	TMTC3	ENSG00000139324	-0.8622767013680068	[44,35]	[25,0]	-5	hSpCas9	negative selection	5450343
88160689	88160711	12	+	27760321	MOLM13	viability	CATTACTATGTACTACTGCTGG	TMTC3	ENSG00000139324	-1.2283354707747653	[74,67]	[0,30]	-6	hSpCas9	negative selection	5450344
88166355	88166377	12	-	27760321	MOLM13	viability	TTAGTTGCCTTGTAGGAGTTGG	TMTC3	ENSG00000139324	-0.6132648030460425	[377,311]	[184,76]	-4	hSpCas9	negative selection	5450345
88166460	88166482	12	-	27760321	MOLM13	viability	CTAGTAATGACTCTATAAGTGG	TMTC3	ENSG00000139324	-2.8049027367704813	[20,4]	[0,0]	-8	hSpCas9	negative selection	5450346
88172648	88172670	12	-	27760321	MOLM13	viability	CGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8662993634262651	[129,123]	[72,179]	6	hSpCas9	negative selection	5450347
88142305	88142328	12	+	27661255	K562	viability	GTAAGACTGCGACGGTACCGGGG	TMTC3	ENSG00000139324	-0.07238843575176879	[1082,1415]	[1029,871]	-3	dCas9-KRAB	negative selection	5518727
88142329	88142352	12	+	27661255	K562	viability	GGCGGGGAAGGACCGAGAGGCGG	TMTC3	ENSG00000139324	-0.26826869137167186	[252,255]	[171,165]	-6	dCas9-KRAB	negative selection	5518728
88142375	88142398	12	+	27661255	K562	viability	GCAAACTGGTGGCCTGAACGAGG	TMTC3	ENSG00000139324	0.28168607428639514	[325,406]	[381,330]	8	dCas9-KRAB	negative selection	5518729
88142509	88142532	12	+	27661255	K562	viability	GCATATTGGGAGGAATTGAGGGG	TMTC3	ENSG00000139324	0.3304081237241434	[780,875]	[878,788]	9	dCas9-KRAB	negative selection	5518730
88154282	88154305	12	+	27260156	BXPC3	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.0644548754118045	[812]	[787,922,839,1022]	1	hSpCas9	negative selection	5576757
88154372	88154395	12	-	27260156	BXPC3	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.19395512784658597	[802]	[801,953,955,1165]	4	hSpCas9	negative selection	5576758
88153383	88153406	12	-	27260156	BXPC3	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	-0.0591743474369828	[178]	[169,154,136,267]	-1	hSpCas9	negative selection	5576759
88160129	88160152	12	-	27260156	BXPC3	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.19401006929669307	[257]	[274,186,211,269]	-4	hSpCas9	negative selection	5641007
88153316	88153339	12	-	27260156	BXPC3	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.16955075798586394	[244]	[345,301,235,253]	4	hSpCas9	negative selection	5641008
88160205	88160228	12	+	27260156	BXPC3	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.05957358519154077	[694]	[792,623,777,843]	1	hSpCas9	negative selection	5641009
88154282	88154305	12	+	27260156	A673	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.10881292471858206	[812]	[1115,904,1026,1178]	2	hSpCas9	negative selection	5698008
88154372	88154395	12	-	27260156	A673	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.018475737825654703	[802]	[1181,783,962,1005]	0	hSpCas9	negative selection	5698009
88153383	88153406	12	-	27260156	A673	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.3952286007123329	[178]	[344,273,249,267]	8	hSpCas9	negative selection	5698010
88160129	88160152	12	-	27260156	A673	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.1791768094830759	[257]	[327,254,242,274]	-4	hSpCas9	negative selection	5762258
88153316	88153339	12	-	27260156	A673	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.4263284100592687	[244]	[436,349,409,388]	8	hSpCas9	negative selection	5762259
88160205	88160228	12	+	27260156	A673	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.11975200568248856	[694]	[820,691,759,807]	-3	hSpCas9	negative selection	5762260
88154282	88154305	12	+	27260156	A375	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.28423595838062365	[812]	[970,1522,1356,855]	4	hSpCas9	negative selection	5819259
88154372	88154395	12	-	27260156	A375	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.2714624015028376	[802]	[1202,1503,994,901]	4	hSpCas9	negative selection	5819260
88153383	88153406	12	-	27260156	A375	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.8030806335652452	[178]	[454,369,452,200]	9	hSpCas9	negative selection	5819261
88160129	88160152	12	-	27260156	A375	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.05989149059160348	[257]	[297,311,433,221]	0	hSpCas9	negative selection	5883509
88153316	88153339	12	-	27260156	A375	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.6692900652069435	[244]	[625,452,317,425]	8	hSpCas9	negative selection	5883510
88160205	88160228	12	+	27260156	A375	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.028733355608479005	[694]	[719,743,901,804]	0	hSpCas9	negative selection	5883511
88154282	88154305	12	+	27260156	COLO741	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.09170611324451539	[812]	[1151,1006,791]	-2	hSpCas9	negative selection	5940510
88154372	88154395	12	-	27260156	COLO741	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.1975776149503079	[802]	[1081,1186,1244]	4	hSpCas9	negative selection	5940511
88153383	88153406	12	-	27260156	COLO741	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.07694429866430519	[178]	[279,171,271]	1	hSpCas9	negative selection	5940512
88160129	88160152	12	-	27260156	COLO741	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.18989649885274762	[257]	[467,320,347]	4	hSpCas9	negative selection	6004760
88153316	88153339	12	-	27260156	COLO741	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.1915465056808321	[244]	[442,295,340]	4	hSpCas9	negative selection	6004761
88160205	88160228	12	+	27260156	COLO741	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.24113698335769707	[694]	[967,770,546]	-5	hSpCas9	negative selection	6004762
88154282	88154305	12	+	27260156	CAL120	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.29223862897346986	[812]	[813,927,735]	-4	hSpCas9	negative selection	6061761
88154372	88154395	12	-	27260156	CAL120	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.2886154854136508	[802]	[1684,1048,1000]	4	hSpCas9	negative selection	6061762
88153383	88153406	12	-	27260156	CAL120	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.6493035443088837	[178]	[408,471,178]	8	hSpCas9	negative selection	6061763
88160129	88160152	12	-	27260156	CAL120	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.48859266915841815	[257]	[422,198,95]	-6	hSpCas9	negative selection	6126011
88153316	88153339	12	-	27260156	CAL120	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	-0.2672937613745454	[244]	[261,181,315]	-4	hSpCas9	negative selection	6126012
88160205	88160228	12	+	27260156	CAL120	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.09737161072213146	[694]	[759,815,840]	-1	hSpCas9	negative selection	6126013
88154282	88154305	12	+	27260156	CADOES1	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.1613618837554377	[812]	[824,881,921,749]	2	hSpCas9	negative selection	6183012
88154372	88154395	12	-	27260156	CADOES1	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.39113391532986286	[802]	[1022,907,991,994]	6	hSpCas9	negative selection	6183013
88153383	88153406	12	-	27260156	CADOES1	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.9096376373268674	[178]	[299,284,249,419]	9	hSpCas9	negative selection	6183014
88160129	88160152	12	-	27260156	CADOES1	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.06571401971259239	[257]	[153,252,237,273]	-1	hSpCas9	negative selection	6247262
88153316	88153339	12	-	27260156	CADOES1	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.7032167262622845	[244]	[413,253,408,407]	9	hSpCas9	negative selection	6247263
88160205	88160228	12	+	27260156	CADOES1	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.11907172984568792	[694]	[688,783,740,589]	2	hSpCas9	negative selection	6247264
88154282	88154305	12	+	27260156	EWS502	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.16023914697902153	[812]	[983,1010,907,934]	3	hSpCas9	negative selection	6304263
88154372	88154395	12	-	27260156	EWS502	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.16802326890922126	[802]	[953,588,1180,1124]	3	hSpCas9	negative selection	6304264
88153383	88153406	12	-	27260156	EWS502	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.44936099411857433	[178]	[210,227,308,296]	7	hSpCas9	negative selection	6304265
88160129	88160152	12	-	27260156	EWS502	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.1347383336656145	[257]	[261,209,305,214]	-2	hSpCas9	negative selection	6368513
88153316	88153339	12	-	27260156	EWS502	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.4530423795305532	[244]	[468,219,357,364]	7	hSpCas9	negative selection	6368514
88160205	88160228	12	+	27260156	EWS502	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.2924244627821715	[694]	[829,801,1082,902]	5	hSpCas9	negative selection	6368515
88154282	88154305	12	+	27260156	EW8	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.12980332012029994	[812]	[1094,759,570,522]	2	hSpCas9	negative selection	6425514
88154372	88154395	12	-	27260156	EW8	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.0956988635170849	[802]	[804,610,636,747]	1	hSpCas9	negative selection	6425515
88153383	88153406	12	-	27260156	EW8	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.24551119264683474	[178]	[193,100,149,247]	4	hSpCas9	negative selection	6425516
88160129	88160152	12	-	27260156	EW8	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.07408630576889175	[257]	[335,278,119,174]	1	hSpCas9	negative selection	6489764
88153316	88153339	12	-	27260156	EW8	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.6014877371212559	[244]	[303,321,292,286]	9	hSpCas9	negative selection	6489765
88160205	88160228	12	+	27260156	EW8	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.20458737345863365	[694]	[631,429,508,394]	-4	hSpCas9	negative selection	6489766
88154282	88154305	12	+	27260156	CORL105	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.0993650592995694	[812]	[904,836,920,896]	-2	hSpCas9	negative selection	6546765
88154372	88154395	12	-	27260156	CORL105	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.09316892218886363	[802]	[903,1035,1043,1028]	1	hSpCas9	negative selection	6546766
88153383	88153406	12	-	27260156	CORL105	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.6425277852424308	[178]	[358,263,410,289]	9	hSpCas9	negative selection	6546767
88160129	88160152	12	-	27260156	CORL105	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.22106712659652905	[257]	[284,295,305,511]	4	hSpCas9	negative selection	6611015
88153316	88153339	12	-	27260156	CORL105	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.21940839095179143	[244]	[251,339,362,381]	4	hSpCas9	negative selection	6611016
88160205	88160228	12	+	27260156	CORL105	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.04106745249601895	[694]	[701,801,888,781]	-1	hSpCas9	negative selection	6611017
88154282	88154305	12	+	27260156	HS294T	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.07066140866306869	[812]	[366,371,291,273]	1	hSpCas9	negative selection	6668016
88154372	88154395	12	-	27260156	HS294T	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.17558764542504335	[802]	[348,307,390,355]	2	hSpCas9	negative selection	6668017
88153383	88153406	12	-	27260156	HS294T	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.1791223213564499	[178]	[104,73,51,79]	2	hSpCas9	negative selection	6668018
88160129	88160152	12	-	27260156	HS294T	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.42507284181094884	[257]	[60,45,118,72]	-6	hSpCas9	negative selection	6732266
88153316	88153339	12	-	27260156	HS294T	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.9188127576339188	[244]	[83,232,177,237]	9	hSpCas9	negative selection	6732267
88160205	88160228	12	+	27260156	HS294T	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.2343677735050369	[694]	[462,182,329,269]	3	hSpCas9	negative selection	6732268
88154282	88154305	12	+	27260156	HCC44	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.14759634533292143	[812]	[1172,823,946,1146]	2	hSpCas9	negative selection	6789267
88154372	88154395	12	-	27260156	HCC44	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.2267692413471295	[802]	[1254,1120,888,959]	3	hSpCas9	negative selection	6789268
88153383	88153406	12	-	27260156	HCC44	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.11831544220976276	[178]	[201,345,215,96]	1	hSpCas9	negative selection	6789269
88160129	88160152	12	-	27260156	HCC44	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.24130010182563644	[257]	[248,363,538,249]	4	hSpCas9	negative selection	6853517
88153316	88153339	12	-	27260156	HCC44	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.4361698611517074	[244]	[460,348,365,331]	7	hSpCas9	negative selection	6853518
88160205	88160228	12	+	27260156	HCC44	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.12727881024903498	[694]	[854,808,1133,688]	2	hSpCas9	negative selection	6853519
88154282	88154305	12	+	27260156	G402	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.02778324848530389	[812]	[1116,1262,844,853]	0	hSpCas9	negative selection	6910518
88154372	88154395	12	-	27260156	G402	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.3093751149485501	[802]	[1398,1073,1066,1324]	4	hSpCas9	negative selection	6910519
88153383	88153406	12	-	27260156	G402	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.6279371358209803	[178]	[430,223,326,371]	7	hSpCas9	negative selection	6910520
88160129	88160152	12	-	27260156	G402	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.16484904330411632	[257]	[381,230,220,298]	-2	hSpCas9	negative selection	6974768
88153316	88153339	12	-	27260156	G402	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	1.1284356489472493	[244]	[1084,445,689,450]	9	hSpCas9	negative selection	6974769
88160205	88160228	12	+	27260156	G402	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.05091943404132204	[694]	[773,938,588,1181]	0	hSpCas9	negative selection	6974770
88154282	88154305	12	+	27260156	L33	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.11420581250458328	[812]	[948,327,569,861]	2	hSpCas9	negative selection	7031769
88154372	88154395	12	-	27260156	L33	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	-0.19084416845463537	[802]	[777,297,463,569]	-4	hSpCas9	negative selection	7031770
88153383	88153406	12	-	27260156	L33	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.39717516974080236	[178]	[248,80,186,198]	7	hSpCas9	negative selection	7031771
88160129	88160152	12	-	27260156	L33	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.4180369042415093	[257]	[171,63,151,202]	-7	hSpCas9	negative selection	7096019
88153316	88153339	12	-	27260156	L33	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.10839994732165681	[244]	[174,124,165,313]	2	hSpCas9	negative selection	7096020
88160205	88160228	12	+	27260156	L33	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.07398406939537239	[694]	[698,248,398,697]	-2	hSpCas9	negative selection	7096021
88154282	88154305	12	+	27260156	K562	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.3834405422607433	[812]	[1049,1192,799,760]	5	hSpCas9	negative selection	7153020
88154372	88154395	12	-	27260156	K562	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.30116259074431795	[802]	[607,1628,856,478]	4	hSpCas9	negative selection	7153021
88153383	88153406	12	-	27260156	K562	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.5704184965088508	[178]	[206,130,297,291]	7	hSpCas9	negative selection	7153022
88160129	88160152	12	-	27260156	K562	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.845088633293354	[257]	[111,72,162,153]	-7	hSpCas9	negative selection	7217270
88153316	88153339	12	-	27260156	K562	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.6882350164441146	[244]	[222,194,487,461]	8	hSpCas9	negative selection	7217271
88160205	88160228	12	+	27260156	K562	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.2844231080155034	[694]	[703,623,1119,564]	3	hSpCas9	negative selection	7217272
88154282	88154305	12	+	27260156	HT29	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.0058226703417305625	[812]	[1121,1267,886,720]	0	hSpCas9	negative selection	7274271
88154372	88154395	12	-	27260156	HT29	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.271543071707007	[802]	[1514,1199,979,1052]	5	hSpCas9	negative selection	7274272
88153383	88153406	12	-	27260156	HT29	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.5630838104105441	[178]	[330,351,336,272]	9	hSpCas9	negative selection	7274273
88160129	88160152	12	-	27260156	HT29	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.13990622857572887	[257]	[372,353,305,134]	-3	hSpCas9	negative selection	7338521
88153316	88153339	12	-	27260156	HT29	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.4114337266746174	[244]	[508,395,367,325]	7	hSpCas9	negative selection	7338522
88160205	88160228	12	+	27260156	HT29	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.06071329435192818	[694]	[877,1015,919,733]	1	hSpCas9	negative selection	7338523
88154282	88154305	12	+	27260156	MHHES1	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.15028071118472108	[812]	[1437,1041,783,864]	2	hSpCas9	negative selection	7395522
88154372	88154395	12	-	27260156	MHHES1	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.01040336494870231	[802]	[935,967,1110,673]	0	hSpCas9	negative selection	7395523
88153383	88153406	12	-	27260156	MHHES1	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.8121074212777454	[178]	[401,512,233,293]	9	hSpCas9	negative selection	7395524
88160129	88160152	12	-	27260156	MHHES1	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.03134402512054146	[257]	[230,404,245,259]	0	hSpCas9	negative selection	7459772
88153316	88153339	12	-	27260156	MHHES1	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.15869119744523386	[244]	[341,281,292,308]	3	hSpCas9	negative selection	7459773
88160205	88160228	12	+	27260156	MHHES1	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.03794878133398116	[694]	[831,643,903,670]	0	hSpCas9	negative selection	7459774
88154282	88154305	12	+	27260156	MEWO	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.1826793211785923	[812]	[988,867,756]	4	hSpCas9	negative selection	7516773
88154372	88154395	12	-	27260156	MEWO	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.19257495155322635	[802]	[1016,677,911]	4	hSpCas9	negative selection	7516774
88153383	88153406	12	-	27260156	MEWO	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.1042186788183721	[178]	[186,250,102]	2	hSpCas9	negative selection	7516775
88160129	88160152	12	-	27260156	MEWO	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.06335091761309808	[257]	[211,207,328]	1	hSpCas9	negative selection	7581023
88153316	88153339	12	-	27260156	MEWO	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.3819326714514434	[244]	[422,312,183]	7	hSpCas9	negative selection	7581024
88160205	88160228	12	+	27260156	MEWO	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.16743340582675448	[694]	[773,488,511]	-4	hSpCas9	negative selection	7581025
88154282	88154305	12	+	27260156	LNCAPCLONEFGC	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.07788844829291108	[812]	[804,678,893,753]	1	hSpCas9	negative selection	7638024
88154372	88154395	12	-	27260156	LNCAPCLONEFGC	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.25809512100753895	[802]	[834,895,849,893]	4	hSpCas9	negative selection	7638025
88153383	88153406	12	-	27260156	LNCAPCLONEFGC	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.32803975898905824	[178]	[194,140,335,165]	5	hSpCas9	negative selection	7638026
88160129	88160152	12	-	27260156	LNCAPCLONEFGC	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.14782659708863133	[257]	[280,195,337,235]	2	hSpCas9	negative selection	7702274
88153316	88153339	12	-	27260156	LNCAPCLONEFGC	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.44468272457694374	[244]	[229,244,293,442]	7	hSpCas9	negative selection	7702275
88160205	88160228	12	+	27260156	LNCAPCLONEFGC	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.1724974359483895	[694]	[550,701,916,701]	2	hSpCas9	negative selection	7702276
88154282	88154305	12	+	27260156	PANC0327	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.11039144378154475	[812]	[862,742,538,536]	-2	hSpCas9	negative selection	7759275
88154372	88154395	12	-	27260156	PANC0327	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.36472183260740587	[802]	[967,840,1048,829]	5	hSpCas9	negative selection	7759276
88153383	88153406	12	-	27260156	PANC0327	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.32929870540839	[178]	[114,233,346,91]	5	hSpCas9	negative selection	7759277
88160129	88160152	12	-	27260156	PANC0327	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.1371805063387329	[257]	[211,101,228,480]	2	hSpCas9	negative selection	7823525
88153316	88153339	12	-	27260156	PANC0327	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	-0.0631585337292524	[244]	[251,144,239,207]	-1	hSpCas9	negative selection	7823526
88160205	88160228	12	+	27260156	PANC0327	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.28895632929487997	[694]	[360,593,584,457]	-4	hSpCas9	negative selection	7823527
88154282	88154305	12	+	27260156	NCIH2009	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.022415275663901002	[812]	[1326,1088,978]	0	hSpCas9	negative selection	7880526
88154372	88154395	12	-	27260156	NCIH2009	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.012946927085880855	[802]	[1205,844,1362]	0	hSpCas9	negative selection	7880527
88153383	88153406	12	-	27260156	NCIH2009	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.5171817920831797	[178]	[280,354,421]	7	hSpCas9	negative selection	7880528
88160129	88160152	12	-	27260156	NCIH2009	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.46267130026458037	[257]	[306,274,210]	-6	hSpCas9	negative selection	7944776
88153316	88153339	12	-	27260156	NCIH2009	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.5377785699376691	[244]	[715,400,417]	7	hSpCas9	negative selection	7944777
88160205	88160228	12	+	27260156	NCIH2009	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.10576688695333758	[694]	[1227,790,752]	-1	hSpCas9	negative selection	7944778
88154282	88154305	12	+	27260156	NCIH1373	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.05048578308828622	[812]	[1603,842,792,164]	0	hSpCas9	negative selection	8001777
88154372	88154395	12	-	27260156	NCIH1373	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.05682985584396072	[802]	[1065,863,779,280]	0	hSpCas9	negative selection	8001778
88153383	88153406	12	-	27260156	NCIH1373	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	1.2065969289306748	[178]	[572,232,530,146]	9	hSpCas9	negative selection	8001779
88160129	88160152	12	-	27260156	NCIH1373	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.5789832313164118	[257]	[172,166,230,52]	-5	hSpCas9	negative selection	8066027
88153316	88153339	12	-	27260156	NCIH1373	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.7705225439728232	[244]	[584,415,636,62]	7	hSpCas9	negative selection	8066028
88160205	88160228	12	+	27260156	NCIH1373	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.15329190392394837	[694]	[548,695,441,293]	-1	hSpCas9	negative selection	8066029
88154282	88154305	12	+	27260156	PATU8902	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.20981642729061278	[812]	[973,628,874,1520]	-2	hSpCas9	negative selection	8123028
88154372	88154395	12	-	27260156	PATU8902	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.6394631458974821	[802]	[1970,1817,1031,2392]	6	hSpCas9	negative selection	8123029
88153383	88153406	12	-	27260156	PATU8902	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	-0.24765004676747937	[178]	[230,160,198,254]	-3	hSpCas9	negative selection	8123030
88160129	88160152	12	-	27260156	PATU8902	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.1338903570571517	[257]	[264,305,299,459]	-1	hSpCas9	negative selection	8187278
88153316	88153339	12	-	27260156	PATU8902	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.6849013058740303	[244]	[662,441,436,691]	7	hSpCas9	negative selection	8187279
88160205	88160228	12	+	27260156	PATU8902	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.4074105975935969	[694]	[1920,1106,1103,995]	4	hSpCas9	negative selection	8187280
88154282	88154305	12	+	27260156	PANC1	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.33271320666523285	[812]	[841,786,1059,808]	5	hSpCas9	negative selection	8244279
88154372	88154395	12	-	27260156	PANC1	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.14813161069971936	[802]	[691,1034,673,708]	2	hSpCas9	negative selection	8244280
88153383	88153406	12	-	27260156	PANC1	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.6310726278858033	[178]	[281,351,112,224]	8	hSpCas9	negative selection	8244281
88160129	88160152	12	-	27260156	PANC1	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.32246788140484584	[257]	[250,302,313,246]	5	hSpCas9	negative selection	8308529
88153316	88153339	12	-	27260156	PANC1	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.5519443990347583	[244]	[225,503,256,286]	8	hSpCas9	negative selection	8308530
88160205	88160228	12	+	27260156	PANC1	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.10564493767956151	[694]	[566,859,799,416]	1	hSpCas9	negative selection	8308531
88154282	88154305	12	+	27260156	PANC0813	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.0062131236282987334	[812]	[1011,971,971,856]	0	hSpCas9	negative selection	8365530
88154372	88154395	12	-	27260156	PANC0813	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	-0.2267091651266565	[802]	[960,896,724,661]	-4	hSpCas9	negative selection	8365531
88153383	88153406	12	-	27260156	PANC0813	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.11711520486069849	[178]	[301,261,209,148]	2	hSpCas9	negative selection	8365532
88160129	88160152	12	-	27260156	PANC0813	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.26730059205558687	[257]	[254,280,254,217]	-4	hSpCas9	negative selection	8429780
88153316	88153339	12	-	27260156	PANC0813	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.18914438009665635	[244]	[361,358,253,338]	3	hSpCas9	negative selection	8429781
88160205	88160228	12	+	27260156	PANC0813	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.32528359189850553	[694]	[787,617,620,593]	-5	hSpCas9	negative selection	8429782
88154282	88154305	12	+	27260156	RDES	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.11638019567039803	[812]	[890,1006,916,1268]	2	hSpCas9	negative selection	8486781
88154372	88154395	12	-	27260156	RDES	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.12840949517034128	[802]	[943,859,1159,1086]	2	hSpCas9	negative selection	8486782
88153383	88153406	12	-	27260156	RDES	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.569732038482363	[178]	[230,311,305,392]	8	hSpCas9	negative selection	8486783
88160129	88160152	12	-	27260156	RDES	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	0.08479375550709933	[257]	[250,400,196,415]	1	hSpCas9	negative selection	8551031
88153316	88153339	12	-	27260156	RDES	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.481529431981619	[244]	[316,328,372,595]	7	hSpCas9	negative selection	8551032
88160205	88160228	12	+	27260156	RDES	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.16081843327382206	[694]	[820,822,966,970]	2	hSpCas9	negative selection	8551033
88154282	88154305	12	+	27260156	PC3	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.12848868859184315	[812]	[435,731,1093,913]	-3	hSpCas9	negative selection	8608032
88154372	88154395	12	-	27260156	PC3	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.19308043527216123	[802]	[666,815,1365,1002]	4	hSpCas9	negative selection	8608033
88153383	88153406	12	-	27260156	PC3	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.09847212052389387	[178]	[128,192,322,176]	2	hSpCas9	negative selection	8608034
88160129	88160152	12	-	27260156	PC3	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.2568705801435567	[257]	[106,204,466,210]	-5	hSpCas9	negative selection	8672282
88153316	88153339	12	-	27260156	PC3	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.12157025771964058	[244]	[118,236,445,382]	2	hSpCas9	negative selection	8672283
88160205	88160228	12	+	27260156	PC3	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.2947672518804097	[694]	[380,604,840,557]	-6	hSpCas9	negative selection	8672284
88154282	88154305	12	+	27260156	PATU8988T	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.26414815172874284	[812]	[911,577,591,1724]	4	hSpCas9	negative selection	8729283
88154372	88154395	12	-	27260156	PATU8988T	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.20824761261331126	[802]	[727,1036,986,840]	3	hSpCas9	negative selection	8729284
88153383	88153406	12	-	27260156	PATU8988T	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	-0.19157308100268167	[178]	[81,152,120,258]	-3	hSpCas9	negative selection	8729285
88160129	88160152	12	-	27260156	PATU8988T	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.3895091931965218	[257]	[187,158,150,266]	-6	hSpCas9	negative selection	8793533
88153316	88153339	12	-	27260156	PATU8988T	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.5368167944993301	[244]	[369,433,223,356]	8	hSpCas9	negative selection	8793534
88160205	88160228	12	+	27260156	PATU8988T	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.00720108943200326	[694]	[583,610,641,844]	0	hSpCas9	negative selection	8793535
88154282	88154305	12	+	27260156	T47D	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.055157233706085274	[812]	[1064,873,1045,958]	1	hSpCas9	negative selection	8850534
88154372	88154395	12	-	27260156	T47D	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.1383691916793386	[802]	[1048,852,1037,1198]	3	hSpCas9	negative selection	8850535
88153383	88153406	12	-	27260156	T47D	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.6685998607436684	[178]	[336,347,281,358]	9	hSpCas9	negative selection	8850536
88160129	88160152	12	-	27260156	T47D	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.14483761753455582	[257]	[271,272,234,308]	-3	hSpCas9	negative selection	8914784
88153316	88153339	12	-	27260156	T47D	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.3308544538159849	[244]	[340,357,327,410]	7	hSpCas9	negative selection	8914785
88160205	88160228	12	+	27260156	T47D	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.05896384988658243	[694]	[802,883,835,846]	1	hSpCas9	negative selection	8914786
88154282	88154305	12	+	27260156	SU8686	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.06505625762783984	[812]	[761,689,704,1310]	1	hSpCas9	negative selection	8971785
88154372	88154395	12	-	27260156	SU8686	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	-0.15916367351403637	[802]	[661,582,779,871]	-3	hSpCas9	negative selection	8971786
88153383	88153406	12	-	27260156	SU8686	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.613734001373472	[178]	[240,250,321,278]	8	hSpCas9	negative selection	8971787
88160129	88160152	12	-	27260156	SU8686	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.24289052857176818	[257]	[203,194,222,250]	-4	hSpCas9	negative selection	9036035
88153316	88153339	12	-	27260156	SU8686	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.191324714432357	[244]	[287,248,303,267]	3	hSpCas9	negative selection	9036036
88160205	88160228	12	+	27260156	SU8686	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.20627591971108145	[694]	[554,573,638,630]	-4	hSpCas9	negative selection	9036037
88154282	88154305	12	+	27260156	SKES1	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.02408367548911039	[812]	[999,766,765,686]	0	hSpCas9	negative selection	9093036
88154372	88154395	12	-	27260156	SKES1	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.32867094696372845	[802]	[1064,1115,1185,701]	7	hSpCas9	negative selection	9093037
88153383	88153406	12	-	27260156	SKES1	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.5592902087033886	[178]	[273,258,308,213]	9	hSpCas9	negative selection	9093038
88160129	88160152	12	-	27260156	SKES1	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.1733856186428362	[257]	[292,259,242,137]	-4	hSpCas9	negative selection	9157286
88153316	88153339	12	-	27260156	SKES1	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.362662057124858	[244]	[370,402,352,162]	7	hSpCas9	negative selection	9157287
88160205	88160228	12	+	27260156	SKES1	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.14097220135346733	[694]	[850,767,687,756]	3	hSpCas9	negative selection	9157288
88154282	88154305	12	+	27260156	TOV112D	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.12409794224966286	[812]	[750,1300,791,796]	2	hSpCas9	negative selection	9214287
88154372	88154395	12	-	27260156	TOV112D	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.3810946736824291	[802]	[1314,1127,659,1124]	7	hSpCas9	negative selection	9214288
88153383	88153406	12	-	27260156	TOV112D	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.4783227187500153	[178]	[329,289,171,223]	8	hSpCas9	negative selection	9214289
88160129	88160152	12	-	27260156	TOV112D	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.12434099916543584	[257]	[326,251,247,134]	-2	hSpCas9	negative selection	9278537
88153316	88153339	12	-	27260156	TOV112D	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.42947335485346405	[244]	[476,201,363,260]	7	hSpCas9	negative selection	9278538
88160205	88160228	12	+	27260156	TOV112D	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	0.0788044481820962	[694]	[530,869,985,572]	1	hSpCas9	negative selection	9278539
88154282	88154305	12	+	27260156	TC71	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	0.039165291024722215	[812]	[795,1003,920,859]	1	hSpCas9	negative selection	9335538
88154372	88154395	12	-	27260156	TC71	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.0223287996932664	[802]	[829,795,861,1018]	0	hSpCas9	negative selection	9335539
88153383	88153406	12	-	27260156	TC71	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.13004728884396433	[178]	[262,166,149,263]	3	hSpCas9	negative selection	9335540
88160129	88160152	12	-	27260156	TC71	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.03723587975385856	[257]	[278,292,255,248]	-1	hSpCas9	negative selection	9399788
88153316	88153339	12	-	27260156	TC71	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.3092340995163323	[244]	[294,396,251,362]	7	hSpCas9	negative selection	9399789
88160205	88160228	12	+	27260156	TC71	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.05977338118630393	[694]	[824,626,643,765]	-1	hSpCas9	negative selection	9399790
88154282	88154305	12	+	27260156	TC32	viability	TTCTAGGTAACAGGAGTTGTTGG	TMTC3	ENSG00000139324	-0.017949625223316112	[812]	[718,356,1114,1019]	0	hSpCas9	negative selection	9456789
88154372	88154395	12	-	27260156	TC32	viability	CATGTACTTATGGAATTGTCTGG	TMTC3	ENSG00000139324	0.1911882150210028	[802]	[816,647,1050,1005]	3	hSpCas9	negative selection	9456790
88153383	88153406	12	-	27260156	TC32	viability	CAGCATGAAAAATCATATTCAGG	TMTC3	ENSG00000139324	0.4087768153734679	[178]	[213,136,315,265]	7	hSpCas9	negative selection	9456791
88160129	88160152	12	-	27260156	TC32	viability	AGCCACTAAAAACACTGTCAAGG	TMTC3	ENSG00000139324	-0.33718399889403905	[257]	[203,111,323,166]	-6	hSpCas9	negative selection	9521039
88153316	88153339	12	-	27260156	TC32	viability	GCGAAATGTCAATACTGTTAAGG	TMTC3	ENSG00000139324	0.7494453930691631	[244]	[249,418,484,391]	9	hSpCas9	negative selection	9521040
88160205	88160228	12	+	27260156	TC32	viability	GTATGAAGTGTTTATTGCCCAGG	TMTC3	ENSG00000139324	-0.13520425957106197	[694]	[451,457,914,647]	-2	hSpCas9	negative selection	9521041
88160208	88160231	12	+	27869803	HPAFII	viability after 27 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-1.0671828972581494	[199]	[35,61,NaN]	-6	hSpCas9	negative selection	9548779
88160708	88160731	12	+	27869803	HPAFII	viability after 27 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.3597126036990439	[510]	[251,421,NaN]	3	hSpCas9	negative selection	9548780
88166390	88166413	12	-	27869803	HPAFII	viability after 27 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	1.5966822059837886	[274]	[559,334,NaN]	9	hSpCas9	negative selection	9548781
88172648	88172671	12	-	27869803	HPAFII	viability after 27 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.4631996197666728	[510]	[269,453,NaN]	4	hSpCas9	negative selection	9548782
88176298	88176321	12	+	27869803	HPAFII	viability after 27 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	1.0679955735455415	[224]	[295,207,NaN]	8	hSpCas9	negative selection	9548783
88190530	88190553	12	+	27869803	HPAFII	viability after 27 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	1.3132586797914285	[395]	[416,600,NaN]	9	hSpCas9	negative selection	9548784
88160208	88160231	12	+	27869803	HPAFII	viability after 15 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.33084276754444064	[199]	[144,186,NaN]	-4	hSpCas9	negative selection	9631228
88160708	88160731	12	+	27869803	HPAFII	viability after 15 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.09847089527005837	[510]	[558,605,NaN]	1	hSpCas9	negative selection	9631229
88166390	88166413	12	-	27869803	HPAFII	viability after 15 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.8003298419601206	[274]	[703,396,NaN]	8	hSpCas9	negative selection	9631230
88172648	88172671	12	-	27869803	HPAFII	viability after 15 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.15251417752667362	[510]	[861,453,NaN]	1	hSpCas9	negative selection	9631231
88176298	88176321	12	+	27869803	HPAFII	viability after 15 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	1.1171844130467483	[224]	[711,407,NaN]	9	hSpCas9	negative selection	9631232
88190530	88190553	12	+	27869803	HPAFII	viability after 15 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.3154014553899406	[395]	[425,593,NaN]	3	hSpCas9	negative selection	9631233
88160208	88160231	12	+	27869803	ASPC1	viability after 36 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.6533146013884099	[468]	[134,72,105]	-6	hSpCas9	negative selection	9713677
88160708	88160731	12	+	27869803	ASPC1	viability after 36 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.7484251054947271	[1251]	[837,661,710]	7	hSpCas9	negative selection	9713678
88166390	88166413	12	-	27869803	ASPC1	viability after 36 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.48366350414240533	[907]	[642,95,573]	5	hSpCas9	negative selection	9713679
88172648	88172671	12	-	27869803	ASPC1	viability after 36 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.25865972082718025	[944]	[620,324,286]	2	hSpCas9	negative selection	9713680
88176298	88176321	12	+	27869803	ASPC1	viability after 36 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	-1.2319941333986792	[768]	[107,95,131]	-8	hSpCas9	negative selection	9713681
88190530	88190553	12	+	27869803	ASPC1	viability after 36 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	-0.9449144775074341	[783]	[38,276,105]	-7	hSpCas9	negative selection	9713682
88160208	88160231	12	+	27869803	PATU8988S	viability after 35 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.04629310784006435	[439]	[177,187,NaN]	0	hSpCas9	negative selection	9796126
88160708	88160731	12	+	27869803	PATU8988S	viability after 35 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.6124385614520607	[1014]	[614,634,NaN]	6	hSpCas9	negative selection	9796127
88166390	88166413	12	-	27869803	PATU8988S	viability after 35 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.34649061196823244	[719]	[236,500,NaN]	4	hSpCas9	negative selection	9796128
88172648	88172671	12	-	27869803	PATU8988S	viability after 35 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.3264776175327959	[788]	[383,412,NaN]	4	hSpCas9	negative selection	9796129
88176298	88176321	12	+	27869803	PATU8988S	viability after 35 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.5832926669921731	[615]	[463,278,NaN]	6	hSpCas9	negative selection	9796130
88190530	88190553	12	+	27869803	PATU8988S	viability after 35 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.8802221515921993	[852]	[566,697,NaN]	8	hSpCas9	negative selection	9796131
88160208	88160231	12	+	27869803	PATU8988S	viability after 31 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	0.15449982673609147	[439]	[189,201,NaN]	2	hSpCas9	negative selection	9878575
88160708	88160731	12	+	27869803	PATU8988S	viability after 31 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.5752607725129568	[1014]	[496,737,NaN]	6	hSpCas9	negative selection	9878576
88166390	88166413	12	-	27869803	PATU8988S	viability after 31 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.2738207075613552	[719]	[248,471,NaN]	3	hSpCas9	negative selection	9878577
88172648	88172671	12	-	27869803	PATU8988S	viability after 31 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.1613387131559444	[788]	[324,385,NaN]	2	hSpCas9	negative selection	9878578
88176298	88176321	12	+	27869803	PATU8988S	viability after 31 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	0.4736826816400398	[615]	[381,288,NaN]	6	hSpCas9	negative selection	9878579
88190530	88190553	12	+	27869803	PATU8988S	viability after 31 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	0.4525796268343545	[852]	[369,586,NaN]	5	hSpCas9	negative selection	9878580
88160208	88160231	12	+	27869803	HPAFII	viability after 35 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.8278775566915979	[199]	[17,100,NaN]	-5	hSpCas9	negative selection	9961024
88160708	88160731	12	+	27869803	HPAFII	viability after 35 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.49544262609418	[510]	[216,530,NaN]	3	hSpCas9	negative selection	9961025
88166390	88166413	12	-	27869803	HPAFII	viability after 35 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	1.4938596700519429	[274]	[464,309,NaN]	8	hSpCas9	negative selection	9961026
88172648	88172671	12	-	27869803	HPAFII	viability after 35 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.8798466277031274	[510]	[317,653,NaN]	6	hSpCas9	negative selection	9961027
88176298	88176321	12	+	27869803	HPAFII	viability after 35 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	1.506114335966965	[224]	[347,295,NaN]	8	hSpCas9	negative selection	9961028
88190530	88190553	12	+	27869803	HPAFII	viability after 35 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	1.1131527634823002	[395]	[340,537,NaN]	7	hSpCas9	negative selection	9961029
88160208	88160231	12	+	27869803	HPAFII	viability after 31 days	TGAAGTGTTTATTGCCCAGGGGG	TMTC3	ENSG00000139324	-0.29997511376512154	[199]	[27,159,NaN]	-2	hSpCas9	negative selection	10043473
88160708	88160731	12	+	27869803	HPAFII	viability after 31 days	TGGACAGTTTCTCCGTGGAAAGG	TMTC3	ENSG00000139324	0.5435508508185192	[510]	[216,636,NaN]	4	hSpCas9	negative selection	10043474
88166390	88166413	12	-	27869803	HPAFII	viability after 31 days	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	1.3189586147581251	[274]	[385,383,NaN]	8	hSpCas9	negative selection	10043475
88172648	88172671	12	-	27869803	HPAFII	viability after 31 days	TCGGCAACAACAAATCCAACTGG	TMTC3	ENSG00000139324	0.5312956989118769	[510]	[301,536,NaN]	4	hSpCas9	negative selection	10043476
88176298	88176321	12	+	27869803	HPAFII	viability after 31 days	CAGGCTACCCATGTTCAGCCAGG	TMTC3	ENSG00000139324	1.2593930882593511	[224]	[319,282,NaN]	8	hSpCas9	negative selection	10043477
88190530	88190553	12	+	27869803	HPAFII	viability after 31 days	CCGAGCAAATGAGTCCCGACTGG	TMTC3	ENSG00000139324	1.3573132624505513	[395]	[488,656,NaN]	8	hSpCas9	negative selection	10043478
88190587	88190610	12	+	28162770	P31FUJ	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.3009349729516043	[171]	[248]	3	hSpCas9	negative selection	10254313
88172703	88172726	12	+	28162770	P31FUJ	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.2266294142229186	[583]	[802]	2	hSpCas9	negative selection	10254314
88160207	88160230	12	+	28162770	P31FUJ	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.5012009758959661	[584]	[972]	5	hSpCas9	negative selection	10254315
88160703	88160726	12	+	28162770	P31FUJ	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.41291432738587386	[247]	[387]	4	hSpCas9	negative selection	10254316
88176234	88176257	12	+	28162770	P31FUJ	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.9399323306147579	[113]	[256]	9	hSpCas9	negative selection	10254317
88166339	88166362	12	-	28162770	P31FUJ	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.40369059694685944	[219]	[341]	4	hSpCas9	negative selection	10254318
88166390	88166413	12	-	28162770	P31FUJ	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.350039879698752	[204]	[188]	-3	hSpCas9	negative selection	10254319
88166429	88166452	12	+	28162770	P31FUJ	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.45626869964751604	[440]	[710]	5	hSpCas9	negative selection	10254320
88172688	88172711	12	-	28162770	P31FUJ	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.5235287146187585	[295]	[499]	6	hSpCas9	negative selection	10254321
88148368	88148391	12	-	28162770	P31FUJ	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.6829847916825361	[193]	[365]	7	hSpCas9	negative selection	10254322
88190587	88190610	12	+	28162770	TF1	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10423679
88172703	88172726	12	+	28162770	TF1	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	NaN	[NaN]	[959]	1	hSpCas9	negative selection	10423680
88160207	88160230	12	+	28162770	TF1	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	NaN	[NaN]	[348]	1	hSpCas9	negative selection	10423681
88160703	88160726	12	+	28162770	TF1	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10423682
88176234	88176257	12	+	28162770	TF1	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10423683
88166339	88166362	12	-	28162770	TF1	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10423684
88166390	88166413	12	-	28162770	TF1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10423685
88166429	88166452	12	+	28162770	TF1	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	NaN	[NaN]	[671]	1	hSpCas9	negative selection	10423686
88172688	88172711	12	-	28162770	TF1	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	NaN	[NaN]	[533]	1	hSpCas9	negative selection	10423687
88148368	88148391	12	-	28162770	TF1	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10423688
88190587	88190610	12	+	28162770	SKM1	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	1.0828410689376542	[46]	[175]	8	hSpCas9	negative selection	10593045
88172703	88172726	12	+	28162770	SKM1	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.06468177844836509	[138]	[256]	0	hSpCas9	negative selection	10593046
88160207	88160230	12	+	28162770	SKM1	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.5475444170980965	[148]	[384]	5	hSpCas9	negative selection	10593047
88160703	88160726	12	+	28162770	SKM1	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.0197362180612623	[76]	[137]	0	hSpCas9	negative selection	10593048
88176234	88176257	12	+	28162770	SKM1	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.3394617246721106	[37]	[84]	3	hSpCas9	negative selection	10593049
88166339	88166362	12	-	28162770	SKM1	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	-0.3480705096895932	[71]	[99]	-3	hSpCas9	negative selection	10593050
88166390	88166413	12	-	28162770	SKM1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.31752911516121735	[42]	[60]	-3	hSpCas9	negative selection	10593051
88166429	88166452	12	+	28162770	SKM1	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.5025711181209207	[108]	[272]	5	hSpCas9	negative selection	10593052
88172688	88172711	12	-	28162770	SKM1	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.47078005120584043	[79]	[195]	4	hSpCas9	negative selection	10593053
88148368	88148391	12	-	28162770	SKM1	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.6054195257126705	[57]	[155]	6	hSpCas9	negative selection	10593054
88190587	88190610	12	+	28162770	SKM1	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	1.0828410689376542	[46]	[175]	8	hSpCas9	negative selection	10762411
88172703	88172726	12	+	28162770	SKM1	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.06468177844836509	[138]	[256]	0	hSpCas9	negative selection	10762412
88160207	88160230	12	+	28162770	SKM1	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.5475444170980965	[148]	[384]	5	hSpCas9	negative selection	10762413
88160703	88160726	12	+	28162770	SKM1	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.0197362180612623	[76]	[137]	0	hSpCas9	negative selection	10762414
88176234	88176257	12	+	28162770	SKM1	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.3394617246721106	[37]	[84]	3	hSpCas9	negative selection	10762415
88166339	88166362	12	-	28162770	SKM1	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	-0.3480705096895932	[71]	[99]	-3	hSpCas9	negative selection	10762416
88166390	88166413	12	-	28162770	SKM1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.31752911516121735	[42]	[60]	-3	hSpCas9	negative selection	10762417
88166429	88166452	12	+	28162770	SKM1	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.5025711181209207	[108]	[272]	5	hSpCas9	negative selection	10762418
88172688	88172711	12	-	28162770	SKM1	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.47078005120584043	[79]	[195]	4	hSpCas9	negative selection	10762419
88148368	88148391	12	-	28162770	SKM1	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.6054195257126705	[57]	[155]	6	hSpCas9	negative selection	10762420
88190587	88190610	12	+	28162770	PL21	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.6114540277254467	[193]	[128]	5	hSpCas9	negative selection	10931777
88172703	88172726	12	+	28162770	PL21	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	1.188912359066066	[386]	[383]	8	hSpCas9	negative selection	10931778
88160207	88160230	12	+	28162770	PL21	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.05599863881724043	[609]	[275]	0	hSpCas9	negative selection	10931779
88160703	88160726	12	+	28162770	PL21	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.12464941490505671	[254]	[120]	1	hSpCas9	negative selection	10931780
88176234	88176257	12	+	28162770	PL21	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.8021756285694178	[111]	[84]	7	hSpCas9	negative selection	10931781
88166339	88166362	12	-	28162770	PL21	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.17504863352648964	[231]	[113]	1	hSpCas9	negative selection	10931782
88166390	88166413	12	-	28162770	PL21	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-1.0186949874339386	[134]	[28]	-6	hSpCas9	negative selection	10931783
88166429	88166452	12	+	28162770	PL21	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.032474120229132764	[318]	[141]	0	hSpCas9	negative selection	10931784
88172688	88172711	12	-	28162770	PL21	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.6890554277394417	[294]	[206]	6	hSpCas9	negative selection	10931785
88148368	88148391	12	-	28162770	PL21	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	-0.20794512414775676	[206]	[77]	-1	hSpCas9	negative selection	10931786
88190587	88190610	12	+	28162770	P31FUJ	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.3009349729516043	[171]	[248]	3	hSpCas9	negative selection	11101143
88172703	88172726	12	+	28162770	P31FUJ	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.2266294142229186	[583]	[802]	2	hSpCas9	negative selection	11101144
88160207	88160230	12	+	28162770	P31FUJ	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.5012009758959661	[584]	[972]	5	hSpCas9	negative selection	11101145
88160703	88160726	12	+	28162770	P31FUJ	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.41291432738587386	[247]	[387]	4	hSpCas9	negative selection	11101146
88176234	88176257	12	+	28162770	P31FUJ	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.9399323306147579	[113]	[256]	9	hSpCas9	negative selection	11101147
88166339	88166362	12	-	28162770	P31FUJ	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.40369059694685944	[219]	[341]	4	hSpCas9	negative selection	11101148
88166390	88166413	12	-	28162770	P31FUJ	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.350039879698752	[204]	[188]	-3	hSpCas9	negative selection	11101149
88166429	88166452	12	+	28162770	P31FUJ	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.45626869964751604	[440]	[710]	5	hSpCas9	negative selection	11101150
88172688	88172711	12	-	28162770	P31FUJ	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.5235287146187585	[295]	[499]	6	hSpCas9	negative selection	11101151
88148368	88148391	12	-	28162770	P31FUJ	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.6829847916825361	[193]	[365]	7	hSpCas9	negative selection	11101152
88190587	88190610	12	+	28162770	OCIAML5	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	1.251163586244659	[90]	[390]	9	hSpCas9	negative selection	11270509
88172703	88172726	12	+	28162770	OCIAML5	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.32306806496573515	[429]	[970]	2	hSpCas9	negative selection	11270510
88160207	88160230	12	+	28162770	OCIAML5	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.4287228292298788	[248]	[604]	3	hSpCas9	negative selection	11270511
88160703	88160726	12	+	28162770	OCIAML5	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.21340305030959467	[166]	[259]	-1	hSpCas9	negative selection	11270512
88176234	88176257	12	+	28162770	OCIAML5	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	1.0287861638429983	[40]	[150]	8	hSpCas9	negative selection	11270513
88166339	88166362	12	-	28162770	OCIAML5	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	1.230854388836021	[130]	[554]	9	hSpCas9	negative selection	11270514
88166390	88166413	12	-	28162770	OCIAML5	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.22659037301100132	[115]	[244]	2	hSpCas9	negative selection	11270515
88166429	88166452	12	+	28162770	OCIAML5	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.36698434338306285	[246]	[574]	3	hSpCas9	negative selection	11270516
88172688	88172711	12	-	28162770	OCIAML5	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.02630398473447193	[234]	[431]	0	hSpCas9	negative selection	11270517
88148368	88148391	12	-	28162770	OCIAML5	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.4049060821825955	[158]	[379]	3	hSpCas9	negative selection	11270518
88190587	88190610	12	+	28162770	EOL1	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.5796363586823329	[347]	[273]	5	hSpCas9	negative selection	11439875
88172703	88172726	12	+	28162770	EOL1	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	-0.11527154654285054	[550]	[267]	-1	hSpCas9	negative selection	11439876
88160207	88160230	12	+	28162770	EOL1	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.33324374397555157	[1025]	[680]	3	hSpCas9	negative selection	11439877
88160703	88160726	12	+	28162770	EOL1	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.7785327479650821	[373]	[337]	7	hSpCas9	negative selection	11439878
88176234	88176257	12	+	28162770	EOL1	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.012010612820874011	[223]	[118]	0	hSpCas9	negative selection	11439879
88166339	88166362	12	-	28162770	EOL1	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.0996344781286258	[433]	[244]	0	hSpCas9	negative selection	11439880
88166390	88166413	12	-	28162770	EOL1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.29177013535622887	[157]	[67]	-2	hSpCas9	negative selection	11439881
88166429	88166452	12	+	28162770	EOL1	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	-0.1596473558458938	[440]	[207]	-1	hSpCas9	negative selection	11439882
88172688	88172711	12	-	28162770	EOL1	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.275770173251935	[311]	[198]	2	hSpCas9	negative selection	11439883
88148368	88148391	12	-	28162770	EOL1	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	-0.32413134128618915	[239]	[100]	-2	hSpCas9	negative selection	11439884
88190587	88190610	12	+	28162770	MOLM13	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.28901542337478325	[282]	[249]	2	hSpCas9	negative selection	11609241
88172703	88172726	12	+	28162770	MOLM13	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.6344475318884923	[571]	[641]	5	hSpCas9	negative selection	11609242
88160207	88160230	12	+	28162770	MOLM13	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.888583507371437	[699]	[936]	6	hSpCas9	negative selection	11609243
88160703	88160726	12	+	28162770	MOLM13	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.5851932909488526	[424]	[460]	4	hSpCas9	negative selection	11609244
88176234	88176257	12	+	28162770	MOLM13	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	1.1559453752298385	[161]	[260]	8	hSpCas9	negative selection	11609245
88166339	88166362	12	-	28162770	MOLM13	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	1.0630476493716237	[328]	[496]	7	hSpCas9	negative selection	11609246
88166390	88166413	12	-	28162770	MOLM13	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.21103355063990928	[232]	[194]	1	hSpCas9	negative selection	11609247
88166429	88166452	12	+	28162770	MOLM13	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	-0.24517794492426254	[458]	[279]	-1	hSpCas9	negative selection	11609248
88172688	88172711	12	-	28162770	MOLM13	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.7781251518589811	[445]	[552]	6	hSpCas9	negative selection	11609249
88148368	88148391	12	-	28162770	MOLM13	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.8484296365469856	[327]	[426]	6	hSpCas9	negative selection	11609250
88190587	88190610	12	+	28162770	HEL	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	-0.06997921591917183	[235]	[143]	0	hSpCas9	negative selection	11778607
88172703	88172726	12	+	28162770	HEL	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.10616781538148135	[556]	[383]	0	hSpCas9	negative selection	11778608
88160207	88160230	12	+	28162770	HEL	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.4885076376631896	[719]	[646]	4	hSpCas9	negative selection	11778609
88160703	88160726	12	+	28162770	HEL	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.17440310656146418	[385]	[278]	1	hSpCas9	negative selection	11778610
88176234	88176257	12	+	28162770	HEL	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.015465526421236442	[172]	[111]	0	hSpCas9	negative selection	11778611
88166339	88166362	12	-	28162770	HEL	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.5935512823728254	[357]	[345]	5	hSpCas9	negative selection	11778612
88166390	88166413	12	-	28162770	HEL	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.00029083661844064856	[191]	[122]	0	hSpCas9	negative selection	11778613
88166429	88166452	12	+	28162770	HEL	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.712132167418031	[344]	[361]	6	hSpCas9	negative selection	11778614
88172688	88172711	12	-	28162770	HEL	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.17609629846796215	[350]	[253]	1	hSpCas9	negative selection	11778615
88148368	88148391	12	-	28162770	HEL	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	-0.0509819837674431	[240]	[148]	0	hSpCas9	negative selection	11778616
88190587	88190610	12	+	28162770	MV411	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.3400868387484498	[195]	[208]	3	hSpCas9	negative selection	11947973
88172703	88172726	12	+	28162770	MV411	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.2551114786681963	[374]	[376]	2	hSpCas9	negative selection	11947974
88160207	88160230	12	+	28162770	MV411	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	-0.1329861934147314	[603]	[463]	-1	hSpCas9	negative selection	11947975
88160703	88160726	12	+	28162770	MV411	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.07583196218438842	[268]	[214]	0	hSpCas9	negative selection	11947976
88176234	88176257	12	+	28162770	MV411	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	-1.0540264415448715	[174]	[70]	-6	hSpCas9	negative selection	11947977
88166339	88166362	12	-	28162770	MV411	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.7606985861497428	[219]	[313]	7	hSpCas9	negative selection	11947978
88166390	88166413	12	-	28162770	MV411	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.44447439784232906	[122]	[140]	4	hSpCas9	negative selection	11947979
88166429	88166452	12	+	28162770	MV411	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.2880795352801212	[279]	[287]	2	hSpCas9	negative selection	11947980
88172688	88172711	12	-	28162770	MV411	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	1.7527406023262808	[241]	[686]	9	hSpCas9	negative selection	11947981
88148368	88148391	12	-	28162770	MV411	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.6136795462267752	[217]	[280]	5	hSpCas9	negative selection	11947982
88190587	88190610	12	+	28162770	MONOMAC1	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.8315323051372171	[74]	[152]	7	hSpCas9	negative selection	12117339
88172703	88172726	12	+	28162770	MONOMAC1	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.2958651006728348	[274]	[386]	3	hSpCas9	negative selection	12117340
88160207	88160230	12	+	28162770	MONOMAC1	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.2993402796712288	[374]	[528]	3	hSpCas9	negative selection	12117341
88160703	88160726	12	+	28162770	MONOMAC1	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.29410363130508177	[179]	[252]	3	hSpCas9	negative selection	12117342
88176234	88176257	12	+	28162770	MONOMAC1	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.403692969519919	[90]	[137]	4	hSpCas9	negative selection	12117343
88166339	88166362	12	-	28162770	MONOMAC1	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.6894619597177869	[151]	[280]	6	hSpCas9	negative selection	12117344
88166390	88166413	12	-	28162770	MONOMAC1	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.46822728175246353	[98]	[156]	4	hSpCas9	negative selection	12117345
88166429	88166452	12	+	28162770	MONOMAC1	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	-0.16141293732883233	[199]	[204]	-1	hSpCas9	negative selection	12117346
88172688	88172711	12	-	28162770	MONOMAC1	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	-0.00034493605445584663	[177]	[203]	0	hSpCas9	negative selection	12117347
88148368	88148391	12	-	28162770	MONOMAC1	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	-0.3614236649604361	[129]	[115]	-3	hSpCas9	negative selection	12117348
88190587	88190610	12	+	28162770	OCIAML2	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	1.4132996219230463	[37]	[560]	9	hSpCas9	negative selection	12286705
88172703	88172726	12	+	28162770	OCIAML2	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.5890434882783069	[73]	[616]	6	hSpCas9	negative selection	12286706
88160207	88160230	12	+	28162770	OCIAML2	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.12329354305061702	[106]	[645]	1	hSpCas9	negative selection	12286707
88160703	88160726	12	+	28162770	OCIAML2	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	-0.16909351918597681	[56]	[280]	-1	hSpCas9	negative selection	12286708
88176234	88176257	12	+	28162770	OCIAML2	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	0.06993855612054156	[21]	[127]	0	hSpCas9	negative selection	12286709
88166339	88166362	12	-	28162770	OCIAML2	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.8550898488075753	[37]	[380]	8	hSpCas9	negative selection	12286710
88166390	88166413	12	-	28162770	OCIAML2	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	0.5675053036446097	[13]	[114]	5	hSpCas9	negative selection	12286711
88166429	88166452	12	+	28162770	OCIAML2	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	0.5156952378607622	[52]	[419]	5	hSpCas9	negative selection	12286712
88172688	88172711	12	-	28162770	OCIAML2	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.7162483094813485	[46]	[427]	7	hSpCas9	negative selection	12286713
88148368	88148391	12	-	28162770	OCIAML2	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.06733519594182547	[25]	[150]	0	hSpCas9	negative selection	12286714
88190587	88190610	12	+	28162770	OCIAML3	viability	CATGAGGCCCGACTTCAAGCAGG	TMTC3	ENSG00000139324	0.4618455944093544	[37]	[157]	4	hSpCas9	negative selection	12456071
88172703	88172726	12	+	28162770	OCIAML3	viability	GTATTTTGGTAGCCCATGGATGG	TMTC3	ENSG00000139324	0.40889809085124806	[123]	[496]	4	hSpCas9	negative selection	12456072
88160207	88160230	12	+	28162770	OCIAML3	viability	ATGAAGTGTTTATTGCCCAGGGG	TMTC3	ENSG00000139324	0.24729461365677863	[143]	[515]	2	hSpCas9	negative selection	12456073
88160703	88160726	12	+	28162770	OCIAML3	viability	ACTGCTGGACAGTTTCTCCGTGG	TMTC3	ENSG00000139324	0.06895737239826616	[77]	[246]	0	hSpCas9	negative selection	12456074
88176234	88176257	12	+	28162770	OCIAML3	viability	GAATAATGTGGGTCATGCTCTGG	TMTC3	ENSG00000139324	-0.28467958221643436	[45]	[113]	-2	hSpCas9	negative selection	12456075
88166339	88166362	12	-	28162770	OCIAML3	viability	GAGTTGGGCTTACAGCAGCTGGG	TMTC3	ENSG00000139324	0.3553662866058688	[57]	[223]	3	hSpCas9	negative selection	12456076
88166390	88166413	12	-	28162770	OCIAML3	viability	ACAACCAAGCATTCACAGGAAGG	TMTC3	ENSG00000139324	-0.009045139603007124	[24]	[74]	0	hSpCas9	negative selection	12456077
88166429	88166452	12	+	28162770	OCIAML3	viability	GCTCTGCTGTGATTGGACCATGG	TMTC3	ENSG00000139324	1.0312628490505302	[99]	[616]	8	hSpCas9	negative selection	12456078
88172688	88172711	12	-	28162770	OCIAML3	viability	CAAAATACAGAACCCCATGCTGG	TMTC3	ENSG00000139324	0.8037518675228453	[62]	[331]	7	hSpCas9	negative selection	12456079
88148368	88148391	12	-	28162770	OCIAML3	viability	AAAGAGGCTGTTCCAATAGCAGG	TMTC3	ENSG00000139324	0.5963235717799864	[38]	[177]	5	hSpCas9	negative selection	12456080