Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7157
• Symbol: TP53
• Description: tumor protein p53

DataSource: http://genomecrispr.dkfz.de/#!/results/TP53

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
7676073	7676096	17	+	26472758	Jiyoye	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.7232212557498015	[323]	[73]	-8	hSpCas9	negative selection	170641
7673740	7673763	17	-	26472758	Jiyoye	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	1.3867112789461578	[70]	[139]	8	hSpCas9	negative selection	170642
7675098	7675121	17	-	26472758	Jiyoye	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.3718423083935929	[247]	[241]	3	hSpCas9	negative selection	170643
7674216	7674239	17	-	26472758	Jiyoye	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.15814783366595897	[245]	[206]	1	hSpCas9	negative selection	170644
7675052	7675075	17	-	26472758	Jiyoye	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.0009617326140355931	[162]	[122]	0	hSpCas9	negative selection	170645
7676510	7676533	17	+	26472758	Jiyoye	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.6172894730638847	[235]	[272]	4	hSpCas9	negative selection	170646
7675166	7675189	17	+	26472758	Jiyoye	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	0.3028387216911377	[42]	[39]	2	hSpCas9	negative selection	170647
7674845	7674868	17	+	26472758	Jiyoye	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-1.4469737520306718	[46]	[12]	-7	hSpCas9	negative selection	170648
7673819	7673842	17	-	26472758	Jiyoye	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	170649
7673764	7673787	17	-	26472758	Jiyoye	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	-0.12716104614531476	[83]	[57]	-1	hSpCas9	negative selection	170650
7676073	7676096	17	+	26472758	KBM7	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.3357095053005317	[1082,988]	[248,142]	-7	hSpCas9	negative selection	361759
7673740	7673763	17	-	26472758	KBM7	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.3615925743788077	[406,452]	[234,286]	4	hSpCas9	negative selection	361760
7675098	7675121	17	-	26472758	KBM7	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.6266953622041772	[939,550]	[870,223]	7	hSpCas9	negative selection	361761
7674216	7674239	17	-	26472758	KBM7	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.2544242306328978	[1025,545]	[279,320]	-2	hSpCas9	negative selection	361762
7675052	7675075	17	-	26472758	KBM7	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.08729765447737556	[596,457]	[137,314]	-1	hSpCas9	negative selection	361763
7676510	7676533	17	+	26472758	KBM7	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.1159978389297176	[1847,1517]	[906,804]	1	hSpCas9	negative selection	361764
7675166	7675189	17	+	26472758	KBM7	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.22102678675265963	[125,151]	[77,37]	-2	hSpCas9	negative selection	361765
7674845	7674868	17	+	26472758	KBM7	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	1.8353382374433989	[69,89]	[247,36]	9	hSpCas9	negative selection	361766
7673819	7673842	17	-	26472758	KBM7	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	-0.43242170986112294	[103,80]	[22,39]	-4	hSpCas9	negative selection	361767
7673764	7673787	17	-	26472758	KBM7	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	0.6048106052598331	[343,271]	[120,305]	6	hSpCas9	negative selection	361768
7676073	7676096	17	+	26472758	Raji	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.3214597634302747	[419]	[38]	-7	hSpCas9	negative selection	552877
7673740	7673763	17	-	26472758	Raji	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	1.0173513345111267	[280]	[131]	8	hSpCas9	negative selection	552878
7675098	7675121	17	-	26472758	Raji	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.0320954080693624	[294]	[69]	0	hSpCas9	negative selection	552879
7674216	7674239	17	-	26472758	Raji	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.016068368627653595	[374]	[87]	0	hSpCas9	negative selection	552880
7675052	7675075	17	-	26472758	Raji	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.023320156270994374	[253]	[57]	0	hSpCas9	negative selection	552881
7676510	7676533	17	+	26472758	Raji	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.7088341588833247	[695]	[263]	6	hSpCas9	negative selection	552882
7675166	7675189	17	+	26472758	Raji	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.7204354892437204	[70]	[9]	-5	hSpCas9	negative selection	552883
7674845	7674868	17	+	26472758	Raji	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-0.7170449000429462	[84]	[11]	-5	hSpCas9	negative selection	552884
7673819	7673842	17	-	26472758	Raji	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	-0.8374749104339394	[76]	[9]	-6	hSpCas9	negative selection	552885
7673764	7673787	17	-	26472758	Raji	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	0.6203961942157408	[184]	[65]	6	hSpCas9	negative selection	552886
7676073	7676096	17	+	26472758	K562	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-3.0567508070541183	[758]	[76]	-8	hSpCas9	negative selection	743995
7673740	7673763	17	-	26472758	K562	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	-0.1515099486646922	[449]	[341]	-1	hSpCas9	negative selection	743996
7675098	7675121	17	-	26472758	K562	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.3538123742102208	[709]	[468]	-2	hSpCas9	negative selection	743997
7674216	7674239	17	-	26472758	K562	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-1.002375037160136	[476]	[200]	-5	hSpCas9	negative selection	743998
7675052	7675075	17	-	26472758	K562	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.5859737304680284	[504]	[283]	-4	hSpCas9	negative selection	743999
7676510	7676533	17	+	26472758	K562	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.24882727209276823	[1306]	[1310]	2	hSpCas9	negative selection	744000
7675166	7675189	17	+	26472758	K562	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.723872412606215	[89]	[45]	-4	hSpCas9	negative selection	744001
7674845	7674868	17	+	26472758	K562	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-0.13890991188505897	[89]	[68]	-1	hSpCas9	negative selection	744002
7673819	7673842	17	-	26472758	K562	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	1.8293812283876034	[29]	[89]	9	hSpCas9	negative selection	744003
7673764	7673787	17	-	26472758	K562	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	-0.016846585314291257	[325]	[271]	0	hSpCas9	negative selection	744004
7673558	7673581	17	-	26627737	DLD1	viability	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	-0.43212896877791235	[333]	[127,77,32]	-4	hSpCas9	negative selection	800284
7673742	7673765	17	-	26627737	DLD1	viability	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.8711985724853084	[305]	[181,204,143]	8	hSpCas9	negative selection	800285
7674216	7674239	17	-	26627737	DLD1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.11023149744834196	[450]	[99,166,126]	-1	hSpCas9	negative selection	800286
7674939	7674962	17	-	26627737	DLD1	viability	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.06458912972789688	[1706]	[546,728,425]	0	hSpCas9	negative selection	800287
7675114	7675137	17	+	26627737	DLD1	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	-0.16544582662289764	[939]	[204,375,216]	-2	hSpCas9	negative selection	800288
7676020	7676043	17	+	26627737	DLD1	viability	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.1920862186733372	[192]	[40,105,18]	-2	hSpCas9	negative selection	800289
7673558	7673581	17	-	26627737	GBM cells	viability after 5 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.5108434232071115	[423]	[651,643]	9	hSpCas9	negative selection	882599
7673742	7673765	17	-	26627737	GBM cells	viability after 5 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.8529014771288493	[222]	[206,224]	9	hSpCas9	negative selection	882600
7674216	7674239	17	-	26627737	GBM cells	viability after 5 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	1.7121875541305636	[277]	[521,454]	9	hSpCas9	negative selection	882601
7674939	7674962	17	-	26627737	GBM cells	viability after 5 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	1.8834072886181765	[911]	[1846,1761]	9	hSpCas9	negative selection	882602
7675114	7675137	17	+	26627737	GBM cells	viability after 5 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	1.4822508035577995	[295]	[391,494]	9	hSpCas9	negative selection	882603
7676020	7676043	17	+	26627737	GBM cells	viability after 5 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	1.7809881503229947	[171]	[276,356]	9	hSpCas9	negative selection	882604
7673558	7673581	17	-	26627737	GBM cells	viability after 13 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	2.2119853052901943	[423]	[1436,763]	9	hSpCas9	negative selection	964914
7673742	7673765	17	-	26627737	GBM cells	viability after 13 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.9432935532626239	[222]	[246,220]	9	hSpCas9	negative selection	964915
7674216	7674239	17	-	26627737	GBM cells	viability after 13 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.92180886213255	[277]	[1281,1029]	9	hSpCas9	negative selection	964916
7674939	7674962	17	-	26627737	GBM cells	viability after 13 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	2.902906797169832	[911]	[4118,3360]	9	hSpCas9	negative selection	964917
7675114	7675137	17	+	26627737	GBM cells	viability after 13 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	2.9947767400978265	[295]	[1288,1272]	9	hSpCas9	negative selection	964918
7676020	7676043	17	+	26627737	GBM cells	viability after 13 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	3.085516409262711	[171]	[950,662]	9	hSpCas9	negative selection	964919
7673558	7673581	17	-	26627737	GBM cells	viability after 21 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	2.9278133901276906	[423]	[1849,1663]	9	hSpCas9	negative selection	1047229
7673742	7673765	17	-	26627737	GBM cells	viability after 21 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	1.685471250502503	[222]	[408,371]	9	hSpCas9	negative selection	1047230
7674216	7674239	17	-	26627737	GBM cells	viability after 21 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	3.967750409654512	[277]	[2454,2278]	9	hSpCas9	negative selection	1047231
7674939	7674962	17	-	26627737	GBM cells	viability after 21 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	3.98557720193738	[911]	[7961,7744]	9	hSpCas9	negative selection	1047232
7675114	7675137	17	+	26627737	GBM cells	viability after 21 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	4.467928050037861	[295]	[3799,3337]	9	hSpCas9	negative selection	1047233
7676020	7676043	17	+	26627737	GBM cells	viability after 21 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	4.264397366841198	[171]	[1846,1748]	9	hSpCas9	negative selection	1047234
7673558	7673581	17	-	26627737	RPE1	viability after 9 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.5405016332266919	[2158]	[1915,2030]	8	hSpCas9	negative selection	1129544
7673742	7673765	17	-	26627737	RPE1	viability after 9 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.8899117716063479	[816]	[366,611]	6	hSpCas9	negative selection	1129545
7674216	7674239	17	-	26627737	RPE1	viability after 9 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.2123373808421523	[2139]	[3006,3230]	9	hSpCas9	negative selection	1129546
7674939	7674962	17	-	26627737	RPE1	viability after 9 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	2.6852484071856995	[4663]	[7824,11412]	9	hSpCas9	negative selection	1129547
7675114	7675137	17	+	26627737	RPE1	viability after 9 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	2.533865782257953	[1751]	[2631,3878]	9	hSpCas9	negative selection	1129548
7676020	7676043	17	+	26627737	RPE1	viability after 9 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	3.1027222420679785	[520]	[1236,1612]	9	hSpCas9	negative selection	1129549
7673558	7673581	17	-	26627737	RPE1	viability after 12 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.917262397627816	[2158]	[2339,2032]	8	hSpCas9	negative selection	1211859
7673742	7673765	17	-	26627737	RPE1	viability after 12 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	1.2868543317579408	[816]	[486,586]	7	hSpCas9	negative selection	1211860
7674216	7674239	17	-	26627737	RPE1	viability after 12 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.280552301720702	[2139]	[2485,3118]	9	hSpCas9	negative selection	1211861
7674939	7674962	17	-	26627737	RPE1	viability after 12 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	2.96385115341435	[4663]	[9671,9886]	9	hSpCas9	negative selection	1211862
7675114	7675137	17	+	26627737	RPE1	viability after 12 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	2.6634580071505	[1751]	[2833,3138]	9	hSpCas9	negative selection	1211863
7676020	7676043	17	+	26627737	RPE1	viability after 12 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	3.604326190008457	[520]	[1630,1777]	9	hSpCas9	negative selection	1211864
7673558	7673581	17	-	26627737	RPE1	viability after 15 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.9412658235791342	[2158]	[2599,2099]	8	hSpCas9	negative selection	1294174
7673742	7673765	17	-	26627737	RPE1	viability after 15 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	1.3409202894282208	[816]	[560,608]	7	hSpCas9	negative selection	1294175
7674216	7674239	17	-	26627737	RPE1	viability after 15 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.7899014139134986	[2139]	[3845,4514]	9	hSpCas9	negative selection	1294176
7674939	7674962	17	-	26627737	RPE1	viability after 15 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	3.287024578625379	[4663]	[13633,12148]	9	hSpCas9	negative selection	1294177
7675114	7675137	17	+	26627737	RPE1	viability after 15 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	3.101994978901735	[1751]	[4155,4350]	9	hSpCas9	negative selection	1294178
7676020	7676043	17	+	26627737	RPE1	viability after 15 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	3.864148615923042	[520]	[2277,2018]	9	hSpCas9	negative selection	1294179
7673558	7673581	17	-	26627737	RPE1	viability after 18 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	2.255307002605468	[2158]	[2876,2679]	9	hSpCas9	negative selection	1376489
7673742	7673765	17	-	26627737	RPE1	viability after 18 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	1.5440126756079218	[816]	[611,675]	7	hSpCas9	negative selection	1376490
7674216	7674239	17	-	26627737	RPE1	viability after 18 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.9834270130682903	[2139]	[3820,5364]	9	hSpCas9	negative selection	1376491
7674939	7674962	17	-	26627737	RPE1	viability after 18 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	3.6262266890177384	[4663]	[15768,15299]	9	hSpCas9	negative selection	1376492
7675114	7675137	17	+	26627737	RPE1	viability after 18 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	3.237499151729849	[1751]	[3944,5008]	9	hSpCas9	negative selection	1376493
7676020	7676043	17	+	26627737	RPE1	viability after 18 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	4.210070581304361	[520]	[2623,2578]	9	hSpCas9	negative selection	1376494
7673558	7673581	17	-	26627737	HeLa	viability after 8 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.15350340277925112	[566]	[164,371,262]	1	hSpCas9	negative selection	1458804
7673742	7673765	17	-	26627737	HeLa	viability after 8 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.4086878043853032	[478]	[205,165,112]	-4	hSpCas9	negative selection	1458805
7674216	7674239	17	-	26627737	HeLa	viability after 8 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.2174671348769645	[600]	[393,122,196]	-2	hSpCas9	negative selection	1458806
7674939	7674962	17	-	26627737	HeLa	viability after 8 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.6912958403195308	[1824]	[434,522,503]	-6	hSpCas9	negative selection	1458807
7675114	7675137	17	+	26627737	HeLa	viability after 8 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.5081386265471312	[592]	[507,286,338]	4	hSpCas9	negative selection	1458808
7676020	7676043	17	+	26627737	HeLa	viability after 8 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.30528055994598424	[295]	[59,153,89]	-3	hSpCas9	negative selection	1458809
7673558	7673581	17	-	26627737	HeLa	viability after 12 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	-0.011705003884142307	[566]	[172,265,252]	0	hSpCas9	negative selection	1541119
7673742	7673765	17	-	26627737	HeLa	viability after 12 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.9942032897501466	[478]	[53,106,134]	-7	hSpCas9	negative selection	1541120
7674216	7674239	17	-	26627737	HeLa	viability after 12 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.018680107145112923	[600]	[329,195,236]	0	hSpCas9	negative selection	1541121
7674939	7674962	17	-	26627737	HeLa	viability after 12 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.2799061491218784	[1824]	[927,493,463]	-2	hSpCas9	negative selection	1541122
7675114	7675137	17	+	26627737	HeLa	viability after 12 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.01110454504151348	[592]	[237,148,363]	0	hSpCas9	negative selection	1541123
7676020	7676043	17	+	26627737	HeLa	viability after 12 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.05786911897146163	[295]	[118,141,88]	0	hSpCas9	negative selection	1541124
7673558	7673581	17	-	26627737	HeLa	viability after 15 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.7699200455505716	[566]	[445,486,234]	6	hSpCas9	negative selection	1623434
7673742	7673765	17	-	26627737	HeLa	viability after 15 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.09340066387376356	[478]	[286,213,114]	0	hSpCas9	negative selection	1623435
7674216	7674239	17	-	26627737	HeLa	viability after 15 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.05098632776712875	[600]	[222,281,200]	0	hSpCas9	negative selection	1623436
7674939	7674962	17	-	26627737	HeLa	viability after 15 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.5534909356603754	[1824]	[392,646,477]	-5	hSpCas9	negative selection	1623437
7675114	7675137	17	+	26627737	HeLa	viability after 15 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.7056489859413305	[592]	[451,278,453]	5	hSpCas9	negative selection	1623438
7676020	7676043	17	+	26627737	HeLa	viability after 15 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	0.7910720735186301	[295]	[331,118,169]	6	hSpCas9	negative selection	1623439
7673558	7673581	17	-	26627737	HeLa	viability after 18 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.8004043581285661	[566]	[322,393,234]	6	hSpCas9	negative selection	1705749
7673742	7673765	17	-	26627737	HeLa	viability after 18 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.10926416734185079	[478]	[193,180,114]	0	hSpCas9	negative selection	1705750
7674216	7674239	17	-	26627737	HeLa	viability after 18 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.046059096515843057	[600]	[149,234,200]	0	hSpCas9	negative selection	1705751
7674939	7674962	17	-	26627737	HeLa	viability after 18 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.5180011160521822	[1824]	[267,560,477]	-4	hSpCas9	negative selection	1705752
7675114	7675137	17	+	26627737	HeLa	viability after 18 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.699054298585622	[592]	[306,221,453]	5	hSpCas9	negative selection	1705753
7676020	7676043	17	+	26627737	HeLa	viability after 18 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	0.7889743327371652	[295]	[216,104,169]	6	hSpCas9	negative selection	1705754
7673558	7673581	17	-	26627737	HCT116	viability after 6 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	4.307801068664774	[921]	[5939,1177]	9	hSpCas9	negative selection	1788064
7673742	7673765	17	-	26627737	HCT116	viability after 6 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	3.975339815605592	[592]	[3417,389]	9	hSpCas9	negative selection	1788065
7674216	7674239	17	-	26627737	HCT116	viability after 6 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	4.324031800257701	[647]	[4071,919]	9	hSpCas9	negative selection	1788066
7674939	7674962	17	-	26627737	HCT116	viability after 6 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	5.497431997080874	[1661]	[27056,3390]	9	hSpCas9	negative selection	1788067
7675114	7675137	17	+	26627737	HCT116	viability after 6 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	7.207669685097297	[651]	[35855,3732]	9	hSpCas9	negative selection	1788068
7676020	7676043	17	+	26627737	HCT116	viability after 6 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	7.848501519537473	[156]	[10485,3042]	9	hSpCas9	negative selection	1788069
7673558	7673581	17	-	26627737	HCT116	viability after 8 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.0807001227795818	[244]	[226,213,412]	8	hSpCas9	negative selection	1870379
7673742	7673765	17	-	26627737	HCT116	viability after 8 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.6608567935117935	[585]	[216,196,198]	-7	hSpCas9	negative selection	1870380
7674216	7674239	17	-	26627737	HCT116	viability after 8 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.33210302227173677	[483]	[151,228,252]	-4	hSpCas9	negative selection	1870381
7674939	7674962	17	-	26627737	HCT116	viability after 8 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.0011870965680067513	[1168]	[507,646,774]	0	hSpCas9	negative selection	1870382
7675114	7675137	17	+	26627737	HCT116	viability after 8 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.032108942950070996	[415]	[203,295,202]	0	hSpCas9	negative selection	1870383
7676020	7676043	17	+	26627737	HCT116	viability after 8 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	0.4915930745892553	[223]	[234,135,150]	5	hSpCas9	negative selection	1870384
7673558	7673581	17	-	26627737	HCT116	viability after 9 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.4245980239612681	[921]	[766,576]	8	hSpCas9	negative selection	1952694
7673742	7673765	17	-	26627737	HCT116	viability after 9 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.879717708818383	[592]	[473,146]	6	hSpCas9	negative selection	1952695
7674216	7674239	17	-	26627737	HCT116	viability after 9 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.9339510145138425	[647]	[1352,1297]	9	hSpCas9	negative selection	1952696
7674939	7674962	17	-	26627737	HCT116	viability after 9 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	2.9023950670757737	[1661]	[3312,3321]	9	hSpCas9	negative selection	1952697
7675114	7675137	17	+	26627737	HCT116	viability after 9 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	3.928768905355254	[651]	[2690,2619]	9	hSpCas9	negative selection	1952698
7676020	7676043	17	+	26627737	HCT116	viability after 9 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	4.152947824229388	[156]	[623,841]	9	hSpCas9	negative selection	1952699
7673558	7673581	17	-	26627737	HCT116	viability after 12 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.5191159427349923	[244]	[187,215,149]	5	hSpCas9	negative selection	2035009
7673742	7673765	17	-	26627737	HCT116	viability after 12 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.6405795297138848	[585]	[86,224,290]	-6	hSpCas9	negative selection	2035010
7674216	7674239	17	-	26627737	HCT116	viability after 12 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.15133099227997937	[483]	[350,346,144]	1	hSpCas9	negative selection	2035011
7674939	7674962	17	-	26627737	HCT116	viability after 12 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.2728023256962191	[1168]	[669,659,900]	3	hSpCas9	negative selection	2035012
7675114	7675137	17	+	26627737	HCT116	viability after 12 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.27038691282483146	[415]	[362,208,208]	2	hSpCas9	negative selection	2035013
7676020	7676043	17	+	26627737	HCT116	viability after 12 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.2887694392488601	[223]	[105,44,135]	-3	hSpCas9	negative selection	2035014
7673558	7673581	17	-	26627737	HCT116	viability after 15 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.1915129843242658	[244]	[538,167,283]	8	hSpCas9	negative selection	2117324
7673742	7673765	17	-	26627737	HCT116	viability after 15 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.4925724849994637	[585]	[256,160,300]	-5	hSpCas9	negative selection	2117325
7674216	7674239	17	-	26627737	HCT116	viability after 15 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.457454815460442	[483]	[463,472,219]	4	hSpCas9	negative selection	2117326
7674939	7674962	17	-	26627737	HCT116	viability after 15 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.5791752532271552	[1168]	[985,775,1241]	5	hSpCas9	negative selection	2117327
7675114	7675137	17	+	26627737	HCT116	viability after 15 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.8702738611366614	[415]	[412,350,541]	7	hSpCas9	negative selection	2117328
7676020	7676043	17	+	26627737	HCT116	viability after 15 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.029962962497153134	[223]	[148,39,190]	0	hSpCas9	negative selection	2117329
7673558	7673581	17	-	26627737	HCT116	viability after 18 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.6725126789458209	[244]	[205,218,136]	5	hSpCas9	negative selection	2199639
7673742	7673765	17	-	26627737	HCT116	viability after 18 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	-0.5282814243801786	[585]	[129,174,289]	-5	hSpCas9	negative selection	2199640
7674216	7674239	17	-	26627737	HCT116	viability after 18 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.6267449610636139	[483]	[394,397,284]	5	hSpCas9	negative selection	2199641
7674939	7674962	17	-	26627737	HCT116	viability after 18 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.5910527402913448	[1168]	[824,681,1067]	5	hSpCas9	negative selection	2199642
7675114	7675137	17	+	26627737	HCT116	viability after 18 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	1.4130216744251178	[415]	[739,525,331]	8	hSpCas9	negative selection	2199643
7676020	7676043	17	+	26627737	HCT116	viability after 18 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.12550386435612237	[223]	[141,62,94]	-1	hSpCas9	negative selection	2199644
7674912	7674935	17	-	24336569	HL60	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	-0.8269594941386956	[310]	[370]	-6	hSpCas9	negative selection	2303099
7674921	7674944	17	-	24336569	HL60	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	0.4977620305431154	[167]	[501]	4	hSpCas9	negative selection	2303100
7674935	7674958	17	-	24336569	HL60	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	-0.3096504857403187	[498]	[851]	-3	hSpCas9	negative selection	2303101
7674941	7674964	17	+	24336569	HL60	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	0.5130844489214578	[449]	[1358]	4	hSpCas9	negative selection	2303102
7675052	7675075	17	-	24336569	HL60	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	1.2935753307180287	[127]	[663]	8	hSpCas9	negative selection	2303103
7675059	7675082	17	+	24336569	HL60	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	-0.6447128711323993	[576]	[780]	-5	hSpCas9	negative selection	2303104
7675090	7675113	17	-	24336569	HL60	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	0.2500699892374496	[957]	[2410]	2	hSpCas9	negative selection	2303105
7675098	7675121	17	-	24336569	HL60	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.26255776510908274	[647]	[1644]	2	hSpCas9	negative selection	2303106
7675108	7675131	17	+	24336569	HL60	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	0.666454327679079	[537]	[1806]	5	hSpCas9	negative selection	2303107
7675114	7675137	17	+	24336569	HL60	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	-0.10100428702454144	[445]	[879]	-1	hSpCas9	negative selection	2303108
7674912	7674935	17	-	24336569	KBM7	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	1.0607077134334444	[321]	[1831]	8	hSpCas9	negative selection	2370276
7674921	7674944	17	-	24336569	KBM7	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	2.3308630335934826	[71]	[987]	9	hSpCas9	negative selection	2370277
7674935	7674958	17	-	24336569	KBM7	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	0.7413143969855722	[360]	[1645]	6	hSpCas9	negative selection	2370278
7674941	7674964	17	+	24336569	KBM7	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	0.16539768034187008	[543]	[1663]	1	hSpCas9	negative selection	2370279
7675052	7675075	17	-	24336569	KBM7	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	1.0831810225823606	[112]	[652]	8	hSpCas9	negative selection	2370280
7675059	7675082	17	+	24336569	KBM7	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	0.35536306094100123	[420]	[1468]	3	hSpCas9	negative selection	2370281
7675090	7675113	17	-	24336569	KBM7	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	0.5819523199256422	[954]	[3898]	5	hSpCas9	negative selection	2370282
7675098	7675121	17	-	24336569	KBM7	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.9341191952098813	[486]	[2537]	7	hSpCas9	negative selection	2370283
7675108	7675131	17	+	24336569	KBM7	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	0.6538960180168382	[445]	[1913]	6	hSpCas9	negative selection	2370284
7675114	7675137	17	+	24336569	KBM7	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.5708515088583047	[699]	[2835]	5	hSpCas9	negative selection	2370285
7675640	7675663	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCTCAAAGAGGCCAAGGCAGG	TP53	ENSG00000141510	-0.2800005536600447	[125,436]	[27,75]	-1	dCas9-VP64	positive selection	2397348
7672155	7672178	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCGGATCACATGG	TP53	ENSG00000141510	0.6864243628519979	[21,12]	[10,0]	3	dCas9-VP64	positive selection	2442729
7675640	7675663	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCTCAAAGAGGCCAAGGCAGG	TP53	ENSG00000141510	0.4364659273333573	[425,542]	[117,302]	3	dCas9-VP64	positive selection	2492603
7672155	7672178	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCGGATCACATGG	TP53	ENSG00000141510	1.29845831928492	[54,84]	[92,21]	7	dCas9-VP64	positive selection	2537984
7675098	7675121	17	-	27260157	DLD1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.0340708545443422	[]	[]	0	hSpCas9	negative selection	2576404
7676246	7676269	17	+	27260157	DLD1	viability	ATCCATTGCTTGGGACGGCAAGG	TP53	ENSG00000141510	1.05767183016748	[]	[]	9	hSpCas9	negative selection	2576703
7674912	7674935	17	-	27260157	DLD1	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	0.174279880600081	[]	[]	3	hSpCas9	negative selection	2582242
7675108	7675131	17	+	27260157	DLD1	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	0.145125032424553	[]	[]	3	hSpCas9	negative selection	2583184
7674921	7674944	17	-	27260157	DLD1	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	0.217287162307488	[]	[]	3	hSpCas9	negative selection	2583527
7675363	7675386	17	+	27260157	DLD1	viability	AGAGTTGGCGTCTACACCTCAGG	TP53	ENSG00000141510	-0.46503838273016	[]	[]	-4	hSpCas9	negative selection	2608226
7675090	7675113	17	-	27260157	DLD1	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	-0.0663070685392772	[]	[]	0	hSpCas9	negative selection	2608860
7676038	7676061	17	+	27260157	DLD1	viability	GACGGAAACCGTAGCTGCCCTGG	TP53	ENSG00000141510	0.205484915331005	[]	[]	3	hSpCas9	negative selection	2609438
7676119	7676142	17	-	27260157	DLD1	viability	ACCAGCAGCTCCTACACCGGCGG	TP53	ENSG00000141510	-0.00065179935700046	[]	[]	0	hSpCas9	negative selection	2609551
7675052	7675075	17	-	27260157	DLD1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.213508228781675	[]	[]	3	hSpCas9	negative selection	2612995
7676488	7676511	17	+	27260157	DLD1	viability	TGGTGGGCCTGCCCTTCCAATGG	TP53	ENSG00000141510	0.239811454319457	[]	[]	4	hSpCas9	negative selection	2616112
7676563	7676586	17	+	27260157	DLD1	viability	TCGACGCTAGGATCTGACTGCGG	TP53	ENSG00000141510	-0.079397529642411	[]	[]	0	hSpCas9	negative selection	2620208
7674935	7674958	17	-	27260157	DLD1	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	0.993446056362972	[]	[]	9	hSpCas9	negative selection	2622487
7676169	7676192	17	+	27260157	DLD1	viability	GGCATTCTGGGAGCTTCATCTGG	TP53	ENSG00000141510	-0.31781437370862	[]	[]	-3	hSpCas9	negative selection	2641024
7675059	7675082	17	+	27260157	DLD1	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	-0.448157537911914	[]	[]	-4	hSpCas9	negative selection	2642127
7675114	7675137	17	+	27260157	DLD1	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.0591233333417021	[]	[]	3	hSpCas9	negative selection	2642448
7676034	7676057	17	-	27260157	DLD1	viability	GGCAGCTACGGTTTCCGTCTGGG	TP53	ENSG00000141510	-0.649822327663722	[]	[]	-5	hSpCas9	negative selection	2642828
7674941	7674964	17	+	27260157	DLD1	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	0.220546274858548	[]	[]	3	hSpCas9	negative selection	2646829
7675098	7675121	17	-	27260157	HT1080	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	4.19979688994914	[]	[]	9	hSpCas9	negative selection	2652534
7676246	7676269	17	+	27260157	HT1080	viability	ATCCATTGCTTGGGACGGCAAGG	TP53	ENSG00000141510	2.653864546589	[]	[]	9	hSpCas9	negative selection	2652833
7674912	7674935	17	-	27260157	HT1080	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	1.72591414267824	[]	[]	9	hSpCas9	negative selection	2658372
7675108	7675131	17	+	27260157	HT1080	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	3.2716469666372	[]	[]	9	hSpCas9	negative selection	2659314
7674921	7674944	17	-	27260157	HT1080	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	1.18252487613043	[]	[]	8	hSpCas9	negative selection	2659657
7675363	7675386	17	+	27260157	HT1080	viability	AGAGTTGGCGTCTACACCTCAGG	TP53	ENSG00000141510	-0.435078141471186	[]	[]	-7	hSpCas9	negative selection	2684356
7675090	7675113	17	-	27260157	HT1080	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	2.97340008079726	[]	[]	9	hSpCas9	negative selection	2684990
7676038	7676061	17	+	27260157	HT1080	viability	GACGGAAACCGTAGCTGCCCTGG	TP53	ENSG00000141510	5.13559651380986	[]	[]	9	hSpCas9	negative selection	2685568
7676119	7676142	17	-	27260157	HT1080	viability	ACCAGCAGCTCCTACACCGGCGG	TP53	ENSG00000141510	3.67508044311191	[]	[]	9	hSpCas9	negative selection	2685681
7675052	7675075	17	-	27260157	HT1080	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	3.08838157285238	[]	[]	9	hSpCas9	negative selection	2689125
7676488	7676511	17	+	27260157	HT1080	viability	TGGTGGGCCTGCCCTTCCAATGG	TP53	ENSG00000141510	-0.190781440772211	[]	[]	0	hSpCas9	negative selection	2692242
7676563	7676586	17	+	27260157	HT1080	viability	TCGACGCTAGGATCTGACTGCGG	TP53	ENSG00000141510	2.383823718854	[]	[]	9	hSpCas9	negative selection	2696338
7674935	7674958	17	-	27260157	HT1080	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	1.63677783000214	[]	[]	9	hSpCas9	negative selection	2698617
7676169	7676192	17	+	27260157	HT1080	viability	GGCATTCTGGGAGCTTCATCTGG	TP53	ENSG00000141510	2.69886796132091	[]	[]	9	hSpCas9	negative selection	2717154
7675059	7675082	17	+	27260157	HT1080	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	4.29704937804377	[]	[]	9	hSpCas9	negative selection	2718257
7675114	7675137	17	+	27260157	HT1080	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	4.11811359468166	[]	[]	9	hSpCas9	negative selection	2718578
7676034	7676057	17	-	27260157	HT1080	viability	GGCAGCTACGGTTTCCGTCTGGG	TP53	ENSG00000141510	3.86612853203787	[]	[]	9	hSpCas9	negative selection	2718958
7674941	7674964	17	+	27260157	HT1080	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	2.77026700513994	[]	[]	9	hSpCas9	negative selection	2722959
7675098	7675121	17	-	27260157	MKN45	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.893064940850319	[]	[]	8	hSpCas9	negative selection	2728664
7676246	7676269	17	+	27260157	MKN45	viability	ATCCATTGCTTGGGACGGCAAGG	TP53	ENSG00000141510	1.77005233475185	[]	[]	9	hSpCas9	negative selection	2728963
7674912	7674935	17	-	27260157	MKN45	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	0.837287646938488	[]	[]	8	hSpCas9	negative selection	2734502
7675108	7675131	17	+	27260157	MKN45	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	1.17457506146537	[]	[]	8	hSpCas9	negative selection	2735444
7674921	7674944	17	-	27260157	MKN45	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	0.180980535329436	[]	[]	5	hSpCas9	negative selection	2735787
7675363	7675386	17	+	27260157	MKN45	viability	AGAGTTGGCGTCTACACCTCAGG	TP53	ENSG00000141510	-0.0509216000855986	[]	[]	0	hSpCas9	negative selection	2760486
7675090	7675113	17	-	27260157	MKN45	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	1.32767654260267	[]	[]	9	hSpCas9	negative selection	2761120
7676038	7676061	17	+	27260157	MKN45	viability	GACGGAAACCGTAGCTGCCCTGG	TP53	ENSG00000141510	1.3114834481517	[]	[]	9	hSpCas9	negative selection	2761698
7676119	7676142	17	-	27260157	MKN45	viability	ACCAGCAGCTCCTACACCGGCGG	TP53	ENSG00000141510	0.978715113215039	[]	[]	8	hSpCas9	negative selection	2761811
7675052	7675075	17	-	27260157	MKN45	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.408981181234766	[]	[]	6	hSpCas9	negative selection	2765255
7676488	7676511	17	+	27260157	MKN45	viability	TGGTGGGCCTGCCCTTCCAATGG	TP53	ENSG00000141510	-0.307816261014416	[]	[]	-1	hSpCas9	negative selection	2768372
7676563	7676586	17	+	27260157	MKN45	viability	TCGACGCTAGGATCTGACTGCGG	TP53	ENSG00000141510	-0.100734965165503	[]	[]	0	hSpCas9	negative selection	2772468
7674935	7674958	17	-	27260157	MKN45	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	1.92717478727327	[]	[]	9	hSpCas9	negative selection	2774747
7676169	7676192	17	+	27260157	MKN45	viability	GGCATTCTGGGAGCTTCATCTGG	TP53	ENSG00000141510	1.99547349776663	[]	[]	9	hSpCas9	negative selection	2793284
7675059	7675082	17	+	27260157	MKN45	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	0.852274244973144	[]	[]	8	hSpCas9	negative selection	2794387
7675114	7675137	17	+	27260157	MKN45	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	1.45988479194944	[]	[]	9	hSpCas9	negative selection	2794708
7676034	7676057	17	-	27260157	MKN45	viability	GGCAGCTACGGTTTCCGTCTGGG	TP53	ENSG00000141510	2.15960293005377	[]	[]	9	hSpCas9	negative selection	2795088
7674941	7674964	17	+	27260157	MKN45	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	0.574578567290871	[]	[]	7	hSpCas9	negative selection	2799089
7675098	7675121	17	-	27260157	RKO	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.000929142352417039	[]	[]	0	hSpCas9	negative selection	2804794
7676246	7676269	17	+	27260157	RKO	viability	ATCCATTGCTTGGGACGGCAAGG	TP53	ENSG00000141510	0.682620313994466	[]	[]	7	hSpCas9	negative selection	2805093
7674912	7674935	17	-	27260157	RKO	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	0.484494059696677	[]	[]	2	hSpCas9	negative selection	2810632
7675108	7675131	17	+	27260157	RKO	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	1.30219165226241	[]	[]	9	hSpCas9	negative selection	2811574
7674921	7674944	17	-	27260157	RKO	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	0.339433351080401	[]	[]	1	hSpCas9	negative selection	2811917
7675363	7675386	17	+	27260157	RKO	viability	AGAGTTGGCGTCTACACCTCAGG	TP53	ENSG00000141510	0.479859821266117	[]	[]	2	hSpCas9	negative selection	2836616
7675090	7675113	17	-	27260157	RKO	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	0.435190671516546	[]	[]	2	hSpCas9	negative selection	2837250
7676038	7676061	17	+	27260157	RKO	viability	GACGGAAACCGTAGCTGCCCTGG	TP53	ENSG00000141510	0.47218071449727	[]	[]	2	hSpCas9	negative selection	2837828
7676119	7676142	17	-	27260157	RKO	viability	ACCAGCAGCTCCTACACCGGCGG	TP53	ENSG00000141510	0.479856377899287	[]	[]	2	hSpCas9	negative selection	2837941
7675052	7675075	17	-	27260157	RKO	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.64343203494351	[]	[]	-7	hSpCas9	negative selection	2841385
7676488	7676511	17	+	27260157	RKO	viability	TGGTGGGCCTGCCCTTCCAATGG	TP53	ENSG00000141510	-1.15752436603075	[]	[]	-8	hSpCas9	negative selection	2844502
7676563	7676586	17	+	27260157	RKO	viability	TCGACGCTAGGATCTGACTGCGG	TP53	ENSG00000141510	-0.215235605475695	[]	[]	-1	hSpCas9	negative selection	2848598
7674935	7674958	17	-	27260157	RKO	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	1.61866894316549	[]	[]	9	hSpCas9	negative selection	2850877
7676169	7676192	17	+	27260157	RKO	viability	GGCATTCTGGGAGCTTCATCTGG	TP53	ENSG00000141510	-0.828123925982231	[]	[]	-7	hSpCas9	negative selection	2869414
7675059	7675082	17	+	27260157	RKO	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	0.154115462745628	[]	[]	0	hSpCas9	negative selection	2870517
7675114	7675137	17	+	27260157	RKO	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.670673109832363	[]	[]	7	hSpCas9	negative selection	2870838
7676034	7676057	17	-	27260157	RKO	viability	GGCAGCTACGGTTTCCGTCTGGG	TP53	ENSG00000141510	-0.463359533523799	[]	[]	-6	hSpCas9	negative selection	2871218
7674941	7674964	17	+	27260157	RKO	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	-0.425565824957705	[]	[]	-6	hSpCas9	negative selection	2875219
7675098	7675121	17	-	27260157	SF268	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-1.27051220131097	[]	[]	-7	hSpCas9	negative selection	2880924
7676246	7676269	17	+	27260157	SF268	viability	ATCCATTGCTTGGGACGGCAAGG	TP53	ENSG00000141510	-0.160016083231388	[]	[]	-1	hSpCas9	negative selection	2881223
7674912	7674935	17	-	27260157	SF268	viability	AAATTTGCGTGTGGAGTATTTGG	TP53	ENSG00000141510	-0.490770225653155	[]	[]	-4	hSpCas9	negative selection	2886762
7675108	7675131	17	+	27260157	SF268	viability	GTGCTGTGACTGCTTGTAGATGG	TP53	ENSG00000141510	-0.528494190279418	[]	[]	-4	hSpCas9	negative selection	2887704
7674921	7674944	17	-	27260157	SF268	viability	AGTGGAAGGAAATTTGCGTGTGG	TP53	ENSG00000141510	-0.708755562079526	[]	[]	-5	hSpCas9	negative selection	2888047
7675363	7675386	17	+	27260157	SF268	viability	AGAGTTGGCGTCTACACCTCAGG	TP53	ENSG00000141510	0.123683471775144	[]	[]	0	hSpCas9	negative selection	2912746
7675090	7675113	17	-	27260157	SF268	viability	AGCACATGACGGAGGTTGTGAGG	TP53	ENSG00000141510	-1.08993485321223	[]	[]	-7	hSpCas9	negative selection	2913380
7676038	7676061	17	+	27260157	SF268	viability	GACGGAAACCGTAGCTGCCCTGG	TP53	ENSG00000141510	-0.617279607029666	[]	[]	-5	hSpCas9	negative selection	2913958
7676119	7676142	17	-	27260157	SF268	viability	ACCAGCAGCTCCTACACCGGCGG	TP53	ENSG00000141510	0.0504079915700709	[]	[]	0	hSpCas9	negative selection	2914071
7675052	7675075	17	-	27260157	SF268	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-1.96497145973724	[]	[]	-8	hSpCas9	negative selection	2917515
7676488	7676511	17	+	27260157	SF268	viability	TGGTGGGCCTGCCCTTCCAATGG	TP53	ENSG00000141510	-0.933457027025185	[]	[]	-6	hSpCas9	negative selection	2920632
7676563	7676586	17	+	27260157	SF268	viability	TCGACGCTAGGATCTGACTGCGG	TP53	ENSG00000141510	-0.848362857987399	[]	[]	-6	hSpCas9	negative selection	2924728
7674935	7674958	17	-	27260157	SF268	viability	CAGCATCTTATCCGAGTGGAAGG	TP53	ENSG00000141510	1.03265779864627	[]	[]	9	hSpCas9	negative selection	2927007
7676169	7676192	17	+	27260157	SF268	viability	GGCATTCTGGGAGCTTCATCTGG	TP53	ENSG00000141510	-2.11540662364341	[]	[]	-9	hSpCas9	negative selection	2945544
7675059	7675082	17	+	27260157	SF268	viability	TATCTGAGCAGCGCTCATGGTGG	TP53	ENSG00000141510	-1.01652768881978	[]	[]	-7	hSpCas9	negative selection	2946647
7675114	7675137	17	+	27260157	SF268	viability	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.185233199963807	[]	[]	0	hSpCas9	negative selection	2946968
7676034	7676057	17	-	27260157	SF268	viability	GGCAGCTACGGTTTCCGTCTGGG	TP53	ENSG00000141510	-0.594475620041079	[]	[]	-4	hSpCas9	negative selection	2947348
7674941	7674964	17	+	27260157	SF268	viability	ACTCGGATAAGATGCTGAGGAGG	TP53	ENSG00000141510	-0.82680331801016	[]	[]	-6	hSpCas9	negative selection	2951349
7675168	7675191	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	0.11889885754103802	[4,4]	[4,3]	2	hSpCas9	positive selection	3028660
7676074	7676097	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-0.2794634041803948	[4,3]	[2,1]	-4	hSpCas9	positive selection	3028661
7675098	7675121	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.23683830503552322	[3,3]	[3,3]	5	hSpCas9	positive selection	3028662
7675120	7675143	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	-0.35132883619334954	[3,2]	[1,1]	-5	hSpCas9	positive selection	3028663
7675168	7675191	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	0.4035700200171539	[4,4]	[5,3]	7	hSpCas9	positive selection	3096518
7676074	7676097	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-0.38131812380284413	[4,4]	[2,1]	-5	hSpCas9	positive selection	3096519
7675098	7675121	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.48728795717391526	[3,3]	[2,4]	8	hSpCas9	positive selection	3096520
7675120	7675143	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	-0.41375545434724437	[3,3]	[3,0]	-6	hSpCas9	positive selection	3096521
7676381	7676404		-	24336571	A375	resistance to PLX after 7 days	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.2626353612340797	[25,23]	[29,30]	7	hSpCas9	positive selection	3152122
7674233	7674256		-	24336571	A375	resistance to PLX after 7 days	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	1.0483482648228444	[76,74]	[153,159]	9	hSpCas9	positive selection	3152123
7674219	7674242		+	24336571	A375	resistance to PLX after 7 days	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	-0.029256269865583384	[65,72]	[65,68]	-1	hSpCas9	positive selection	3152124
7676377	7676400		+	24336571	A375	resistance to PLX after 7 days	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	-0.16226127946362467	[45,50]	[42,42]	-5	hSpCas9	positive selection	3152125
7676381	7676404		-	24336571	A375	resistance to PLX after 14 days	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	1.8665106647472705	[25,17]	[38,35]	9	hSpCas9	positive selection	3209915
7674233	7674256		-	24336571	A375	resistance to PLX after 14 days	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	3.0685613535790393	[93,84]	[345,357]	9	hSpCas9	positive selection	3209916
7674219	7674242		+	24336571	A375	resistance to PLX after 14 days	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.5770290971232677	[60,74]	[54,38]	5	hSpCas9	positive selection	3209917
7676377	7676400		+	24336571	A375	resistance to PLX after 14 days	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	-0.060923902161962085	[37,57]	[22,18]	0	hSpCas9	positive selection	3209918
7676381	7676404		-	24336571	A375	viability after 7 days	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.7355884917407065	[44]	[25,23]	-8	hSpCas9	negative selection	3267708
7674233	7674256		-	24336571	A375	viability after 7 days	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	1.0144035939437555	[38]	[76,74]	9	hSpCas9	negative selection	3267709
7674219	7674242		+	24336571	A375	viability after 7 days	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.14626687673070826	[65]	[65,72]	2	hSpCas9	negative selection	3267710
7676377	7676400		+	24336571	A375	viability after 7 days	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	0.7192332845941751	[30]	[45,50]	9	hSpCas9	negative selection	3267711
7676381	7676404		-	24336571	A375	viability after 14 days	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.9372378985568233	[44]	[25,17]	-8	hSpCas9	negative selection	3325501
7674233	7674256		-	24336571	A375	viability after 14 days	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	1.2658056442563985	[38]	[93,84]	9	hSpCas9	negative selection	3325502
7674219	7674242		+	24336571	A375	viability after 14 days	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.13519261252997472	[65]	[60,74]	1	hSpCas9	negative selection	3325503
7676377	7676400		+	24336571	A375	viability after 14 days	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	0.7325905178963261	[30]	[37,57]	8	hSpCas9	negative selection	3325504
7675052	7675075	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	1.4244361972810935	[56,56]	[0,0]	6	hSpCas9	positive selection	3398609
7676248	7676271	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.12205215562542726	[332,332]	[1,1]	0	hSpCas9	positive selection	3398610
7676381	7676404	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	1.507791943776573	[268,268]	[4,4]	6	hSpCas9	positive selection	3398611
7675167	7675190	17	+	26780180	HT29	viability (Avana library 4 designs)	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	0.305446704505411	[]	[]	1	hSpCas9	negative selection	3467473
7676073	7676096	17	+	26780180	HT29	viability (Avana library 4 designs)	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	2.11796352494584	[]	[]	7	hSpCas9	negative selection	3467474
7675098	7675121	17	-	26780180	HT29	viability (Avana library 4 designs)	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.418675571214	[]	[]	1	hSpCas9	negative selection	3467475
7675119	7675142	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	1.90533835699997	[]	[]	7	hSpCas9	negative selection	3467476
7675119	7675142	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	6.22754919336776	[]	[]	9	hSpCas9	negative selection	3571646
7675098	7675121	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	5.86096002522898	[]	[]	9	hSpCas9	negative selection	3571647
7675167	7675190	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	4.36521464435966	[]	[]	7	hSpCas9	negative selection	3571648
7676073	7676096	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	5.02590386736286	[]	[]	8	hSpCas9	negative selection	3571649
7676510	7676533	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-3.37317571472023	[]	[]	-4	hSpCas9	negative selection	3571650
7676164	7676187	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGCTCCCAGAATGCCAGAGG	TP53	ENSG00000141510	6.63783804261905	[]	[]	9	hSpCas9	negative selection	3571651
7675119	7675142	17	+	26780180	A375	viability (Avana lentiGuide)	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	-6.86214785752319	[]	[]	-9	hSpCas9	negative selection	3680305
7675098	7675121	17	-	26780180	A375	viability (Avana lentiGuide)	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-10.8270314803939	[]	[]	-9	hSpCas9	negative selection	3680306
7675167	7675190	17	+	26780180	A375	viability (Avana lentiGuide)	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	-12.1612524802261	[]	[]	-9	hSpCas9	negative selection	3680307
7676073	7676096	17	+	26780180	A375	viability (Avana lentiGuide)	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.682453404775248	[]	[]	0	hSpCas9	negative selection	3680308
7676510	7676533	17	+	26780180	A375	viability (Avana lentiGuide)	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	1.56035360702309	[]	[]	1	hSpCas9	negative selection	3680309
7676164	7676187	17	-	26780180	A375	viability (Avana lentiGuide)	TGAAGCTCCCAGAATGCCAGAGG	TP53	ENSG00000141510	-6.85106987358446	[]	[]	-9	hSpCas9	negative selection	3680310
7675119	7675142	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	0.5057516683150028	[4]	[6,6]	9	hSpCas9	positive selection	3788912
7675098	7675121	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.5135330492994457	[5]	[8,6]	9	hSpCas9	positive selection	3788913
7675167	7675190	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	0.3223111530158475	[6]	[7,7]	8	hSpCas9	positive selection	3788914
7676073	7676096	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.43763426553763396	[5]	[6,7]	9	hSpCas9	positive selection	3788915
7676510	7676533	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.46192410067680756	[5]	[3,3]	-6	hSpCas9	positive selection	3788916
7676164	7676187	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGCTCCCAGAATGCCAGAGG	TP53	ENSG00000141510	0.5464559307445116	[4]	[7,7]	9	hSpCas9	positive selection	3788917
7675119	7675142	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGTAGATGGCCATGGCGCGG	TP53	ENSG00000141510	0.2582407309176109	[5]	[4,6]	7	hSpCas9	positive selection	3897519
7675098	7675121	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.4433796219993207	[5]	[7,6]	9	hSpCas9	positive selection	3897520
7675167	7675190	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCAACCCACAGCTGCACAGGG	TP53	ENSG00000141510	0.4994391582450989	[6]	[7,8]	9	hSpCas9	positive selection	3897521
7676073	7676096	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.4959148474418811	[5]	[6,7]	9	hSpCas9	positive selection	3897522
7676510	7676533	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.16314241812569988	[5]	[2,5]	-2	hSpCas9	positive selection	3897523
7676164	7676187	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGCTCCCAGAATGCCAGAGG	TP53	ENSG00000141510	0.5592054230862583	[5]	[7,6]	9	hSpCas9	positive selection	3897524
7676381	7676404	17	-	26780180	A375	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.629246154524711	[]	[]	2	hSpCas9	negative selection	4006893
7676210	7676233	17	-	26780180	A375	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.452121683282527	[]	[]	-9	hSpCas9	negative selection	4006894
7676248	7676271	17	-	26780180	A375	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.685110120501678	[]	[]	2	hSpCas9	negative selection	4006895
7674219	7674242	17	+	26780180	A375	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.0441256753593205	[]	[]	0	hSpCas9	negative selection	4006896
7675056	7675079	17	+	26780180	A375	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.384743851484184	[]	[]	0	hSpCas9	negative selection	4006897
7675052	7675075	17	-	26780180	A375	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.493180438716886	[]	[]	1	hSpCas9	negative selection	4006898
7676381	7676404	17	-	26780180	HT29	viability (GeCKOv2 library)	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	2.15132398438965	[]	[]	9	hSpCas9	negative selection	4114859
7676210	7676233	17	-	26780180	HT29	viability (GeCKOv2 library)	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.786642943933199	[]	[]	3	hSpCas9	negative selection	4114860
7676248	7676271	17	-	26780180	HT29	viability (GeCKOv2 library)	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	2.16965175254018	[]	[]	9	hSpCas9	negative selection	4114861
7674219	7674242	17	+	26780180	HT29	viability (GeCKOv2 library)	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.23414510138413	[]	[]	6	hSpCas9	negative selection	4114862
7675056	7675079	17	+	26780180	HT29	viability (GeCKOv2 library)	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.80478598325842	[]	[]	3	hSpCas9	negative selection	4114863
7675052	7675075	17	-	26780180	HT29	viability (GeCKOv2 library)	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.705493504237571	[]	[]	2	hSpCas9	negative selection	4114864
7676381	7676404	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.5020499743731273	[4]	[4,5]	9	hSpCas9	positive selection	4178656
7674233	7674256	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	0.9348908361991373	[5]	[7,8]	9	hSpCas9	positive selection	4178657
7674219	7674242	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.42883258156772686	[5]	[4,5]	8	hSpCas9	positive selection	4178658
7676377	7676400	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	0.3119305289114014	[5]	[4,4]	7	hSpCas9	positive selection	4178659
7676381	7676404	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	1.5725074429530812	[5]	[7,7,7,6]	9	hSpCas9	positive selection	4242678
7674233	7674256	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGTGTAACAGTTCCTGCATGG	TP53	ENSG00000141510	1.7445410987039263	[5]	[8,8,8,7]	9	hSpCas9	positive selection	4242679
7674219	7674242	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.5087157815342764	[5]	[8,6,6,6]	9	hSpCas9	positive selection	4242680
7676377	7676400	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTACCAGAACGTTGTTTTCAGG	TP53	ENSG00000141510	1.3342471839959313	[4]	[4,4,5,5]	9	hSpCas9	positive selection	4242681
7674219	7674242	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.7098950910456833	[3]	[4,5]	9	hSpCas9	positive selection	4304669
7675056	7675079	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.2628629575707058	[2]	[2,0]	-5	hSpCas9	positive selection	4304670
7676210	7676233	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.6945281558448698	[1]	[4,1]	9	hSpCas9	positive selection	4304671
7675052	7675075	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.4678770784298441	[1]	[2,1]	8	hSpCas9	positive selection	4368918
7676248	7676271	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.6304508254151541	[3]	[3,3]	9	hSpCas9	positive selection	4368919
7676381	7676404	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.23244863384289188	[2]	[2,2]	5	hSpCas9	positive selection	4368920
7675098	7675120	17	-	27760321	OCIAML3	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.765451420426113	[758,660]	[708,1244]	8	hSpCas9	negative selection	4449343
7675151	7675173	17	-	27760321	OCIAML3	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	0.4374066195282149	[814,638]	[654,907]	5	hSpCas9	negative selection	4449344
7675200	7675222	17	-	27760321	OCIAML3	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	-0.44036788168968544	[158,148]	[80,98]	-4	hSpCas9	negative selection	4449345
7676211	7676233	17	+	27760321	OCIAML3	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	0.2834498115957008	[716,574]	[524,723]	3	hSpCas9	negative selection	4449346
7676249	7676271	17	+	27760321	OCIAML3	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	0.561724778851789	[664,596]	[658,816]	6	hSpCas9	negative selection	4449347
7675098	7675120	17	-	27760321	OCIAML2	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	1.3694006098401683	[758,660]	[1274,1750]	9	hSpCas9	negative selection	4532806
7675151	7675173	17	-	27760321	OCIAML2	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	1.1130077716844253	[814,638]	[1153,1407]	9	hSpCas9	negative selection	4532807
7675200	7675222	17	-	27760321	OCIAML2	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.5932419522872818	[158,148]	[178,199]	7	hSpCas9	negative selection	4532808
7676211	7676233	17	+	27760321	OCIAML2	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	1.4353549215497097	[716,574]	[1267,1585]	9	hSpCas9	negative selection	4532809
7676249	7676271	17	+	27760321	OCIAML2	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	0.9070322850094146	[664,596]	[773,1195]	9	hSpCas9	negative selection	4532810
7675098	7675120	17	-	27760321	MV411	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	2.8130504398947016	[758,660]	[2851,3934]	9	hSpCas9	negative selection	4616269
7675151	7675173	17	-	27760321	MV411	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	2.6908220434720977	[814,638]	[3120,3010]	9	hSpCas9	negative selection	4616270
7675200	7675222	17	-	27760321	MV411	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	-0.8913028831419361	[158,148]	[81,13]	-5	hSpCas9	negative selection	4616271
7676211	7676233	17	+	27760321	MV411	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	2.4699443678198234	[716,574]	[1894,3028]	9	hSpCas9	negative selection	4616272
7676249	7676271	17	+	27760321	MV411	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	2.4313732795565626	[664,596]	[2384,2030]	9	hSpCas9	negative selection	4616273
7675098	7675120	17	-	27760321	HL60	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.790672159159126	[758,660]	[997,1003]	8	hSpCas9	negative selection	4699732
7675151	7675173	17	-	27760321	HL60	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	0.027459775541806564	[814,638]	[559,644]	0	hSpCas9	negative selection	4699733
7675200	7675222	17	-	27760321	HL60	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.7164493580759054	[158,148]	[134,282]	7	hSpCas9	negative selection	4699734
7676211	7676233	17	+	27760321	HL60	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	0.6586515574358848	[716,574]	[902,748]	7	hSpCas9	negative selection	4699735
7676249	7676271	17	+	27760321	HL60	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	0.6123220019881139	[664,596]	[739,836]	7	hSpCas9	negative selection	4699736
7675098	7675120	17	-	27760321	HT1080	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	5.42265622481867	[660,515]	[10127,9976]	9	hSpCas9	negative selection	4783195
7675151	7675173	17	-	27760321	HT1080	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	5.965414376455892	[638,498]	[15605,12584]	9	hSpCas9	negative selection	4783196
7675200	7675222	17	-	27760321	HT1080	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	-0.02912390828377709	[148,115]	[87,11]	0	hSpCas9	negative selection	4783197
7676211	7676233	17	+	27760321	HT1080	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	6.243417103113014	[574,448]	[17750,12937]	9	hSpCas9	negative selection	4783198
7676249	7676271	17	+	27760321	HT1080	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	4.625022213187039	[596,465]	[7073,3199]	9	hSpCas9	negative selection	4783199
7675098	7675120	17	-	27760321	HT29	viability after 7 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.0206824837964823	[660,515]	[1042,841,404]	0	hSpCas9	negative selection	4866658
7675151	7675173	17	-	27760321	HT29	viability after 7 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-0.16117048157883862	[638,498]	[448,937,548]	-2	hSpCas9	negative selection	4866659
7675200	7675222	17	-	27760321	HT29	viability after 7 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.5097921611949807	[148,115]	[125,290,291]	7	hSpCas9	negative selection	4866660
7676211	7676233	17	+	27760321	HT29	viability after 7 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-0.37921228932828155	[574,448]	[640,423,472]	-5	hSpCas9	negative selection	4866661
7676249	7676271	17	+	27760321	HT29	viability after 7 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	-0.12618536684699083	[596,465]	[655,575,648]	-2	hSpCas9	negative selection	4866662
7675098	7675120	17	-	27760321	HT29	viability after 25 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-1.1292507401383036	[660,515]	[290,237,403]	-7	hSpCas9	negative selection	4950121
7675151	7675173	17	-	27760321	HT29	viability after 25 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-1.5054836504231304	[638,498]	[202,190,301]	-7	hSpCas9	negative selection	4950122
7675200	7675222	17	-	27760321	HT29	viability after 25 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.2183044882237708	[148,115]	[140,198,191]	2	hSpCas9	negative selection	4950123
7676211	7676233	17	+	27760321	HT29	viability after 25 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-1.524462157183323	[574,448]	[327,139,125]	-7	hSpCas9	negative selection	4950124
7676249	7676271	17	+	27760321	HT29	viability after 25 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	-1.2588710575823758	[596,465]	[214,281,267]	-7	hSpCas9	negative selection	4950125
7675098	7675120	17	-	27760321	HT29	viability after 22 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-1.1079717182187288	[660,515]	[268,381,296]	-7	hSpCas9	negative selection	5033584
7675151	7675173	17	-	27760321	HT29	viability after 22 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-1.3058296078131777	[638,498]	[279,235,281]	-7	hSpCas9	negative selection	5033585
7675200	7675222	17	-	27760321	HT29	viability after 22 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	-0.2674204294175453	[148,115]	[147,121,110]	-3	hSpCas9	negative selection	5033586
7676211	7676233	17	+	27760321	HT29	viability after 22 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-1.0158154865239903	[574,448]	[344,423,105]	-6	hSpCas9	negative selection	5033587
7676249	7676271	17	+	27760321	HT29	viability after 22 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	-0.8192829055479585	[596,465]	[261,329,455]	-6	hSpCas9	negative selection	5033588
7675098	7675120	17	-	27760321	HT29	viability after 19 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.8959852005147486	[660,515]	[341,304,432]	-6	hSpCas9	negative selection	5117047
7675151	7675173	17	-	27760321	HT29	viability after 19 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-0.5213274277482763	[638,498]	[579,441,354]	-4	hSpCas9	negative selection	5117048
7675200	7675222	17	-	27760321	HT29	viability after 19 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.15744274577399286	[148,115]	[223,183,106]	1	hSpCas9	negative selection	5117049
7676211	7676233	17	+	27760321	HT29	viability after 19 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-1.0882025310958656	[574,448]	[375,248,213]	-6	hSpCas9	negative selection	5117050
7676249	7676271	17	+	27760321	HT29	viability after 19 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	-0.9871655132225603	[596,465]	[231,401,278]	-6	hSpCas9	negative selection	5117051
7675098	7675120	17	-	27760321	HT29	viability after 16 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.2929973650539613	[660,515]	[573,636,401]	-3	hSpCas9	negative selection	5200510
7675151	7675173	17	-	27760321	HT29	viability after 16 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-0.26189929220345154	[638,498]	[581,436,580]	-3	hSpCas9	negative selection	5200511
7675200	7675222	17	-	27760321	HT29	viability after 16 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.11803271827288109	[148,115]	[213,143,129]	1	hSpCas9	negative selection	5200512
7676211	7676233	17	+	27760321	HT29	viability after 16 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-0.7643266790647141	[574,448]	[474,172,380]	-6	hSpCas9	negative selection	5200513
7676249	7676271	17	+	27760321	HT29	viability after 16 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	-0.1841095429812002	[596,465]	[441,616,500]	-2	hSpCas9	negative selection	5200514
7675098	7675120	17	-	27760321	HT29	viability after 13 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.038259499201529934	[660,515]	[506,927,565]	0	hSpCas9	negative selection	5283973
7675151	7675173	17	-	27760321	HT29	viability after 13 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-0.1373878252572459	[638,498]	[648,631,523]	-2	hSpCas9	negative selection	5283974
7675200	7675222	17	-	27760321	HT29	viability after 13 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.10875240603731307	[148,115]	[189,156,150]	1	hSpCas9	negative selection	5283975
7676211	7676233	17	+	27760321	HT29	viability after 13 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-0.4399723817335482	[574,448]	[433,449,429]	-5	hSpCas9	negative selection	5283976
7676249	7676271	17	+	27760321	HT29	viability after 13 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	0.10142870821910888	[596,465]	[634,713,636]	1	hSpCas9	negative selection	5283977
7675098	7675120	17	-	27760321	HT29	viability after 10 days	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.5093827422613222	[660,515]	[495,634,422]	-6	hSpCas9	negative selection	5367436
7675151	7675173	17	-	27760321	HT29	viability after 10 days	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	-0.23439532682057285	[638,498]	[592,635,583]	-3	hSpCas9	negative selection	5367437
7675200	7675222	17	-	27760321	HT29	viability after 10 days	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.053167780674651555	[148,115]	[189,206,119]	0	hSpCas9	negative selection	5367438
7676211	7676233	17	+	27760321	HT29	viability after 10 days	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	-0.3644982090512084	[574,448]	[549,460,477]	-5	hSpCas9	negative selection	5367439
7676249	7676271	17	+	27760321	HT29	viability after 10 days	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	0.05380662579091955	[596,465]	[712,449,891]	0	hSpCas9	negative selection	5367440
7675098	7675120	17	-	27760321	MOLM13	viability	CAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	2.639293415336096	[758,660]	[2539,2446]	9	hSpCas9	negative selection	5450899
7675151	7675173	17	-	27760321	MOLM13	viability	TTGATTCCACACCCCCGCCCGG	TP53	ENSG00000141510	2.22753967591013	[814,638]	[2557,1354]	9	hSpCas9	negative selection	5450900
7675200	7675222	17	-	27760321	MOLM13	viability	AACAAGATGTTTTGCCAACTGG	TP53	ENSG00000141510	0.4270585465935124	[158,148]	[151,86]	3	hSpCas9	negative selection	5450901
7676211	7676233	17	+	27760321	MOLM13	viability	CATTGTTCAATATCGTCCGGGG	TP53	ENSG00000141510	2.1655072401040036	[716,574]	[2913,528]	9	hSpCas9	negative selection	5450902
7676249	7676271	17	+	27760321	MOLM13	viability	CATTGCTTGGGACGGCAAGGGG	TP53	ENSG00000141510	1.7798020883192864	[664,596]	[1690,820]	9	hSpCas9	negative selection	5450903
7674219	7674242	17	+	27260156	BXPC3	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.21740326577015234	[847]	[892,1033,1031,1191]	5	hSpCas9	negative selection	5577129
7675056	7675079	17	+	27260156	BXPC3	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.32996129296790694	[267]	[274,255,441,462]	7	hSpCas9	negative selection	5577130
7676210	7676233	17	-	27260156	BXPC3	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.08630605981432149	[178]	[138,192,258,211]	2	hSpCas9	negative selection	5577131
7675052	7675075	17	-	27260156	BXPC3	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.12555565096272225	[133]	[174,117,181,132]	2	hSpCas9	negative selection	5641378
7676248	7676271	17	-	27260156	BXPC3	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.043377040434533054	[470]	[395,465,518,545]	-1	hSpCas9	negative selection	5641379
7676381	7676404	17	-	27260156	BXPC3	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.09177347385561757	[452]	[368,423,490,508]	-2	hSpCas9	negative selection	5641380
7674219	7674242	17	+	27260156	A673	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.21201277983294142	[847]	[1253,1086,1074,1318]	5	hSpCas9	negative selection	5698380
7675056	7675079	17	+	27260156	A673	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.02245304657406466	[267]	[393,255,356,307]	0	hSpCas9	negative selection	5698381
7676210	7676233	17	-	27260156	A673	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.22992528265595324	[178]	[358,161,270,228]	5	hSpCas9	negative selection	5698382
7675052	7675075	17	-	27260156	A673	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.05258663861624946	[133]	[163,163,169,120]	-1	hSpCas9	negative selection	5762629
7676248	7676271	17	-	27260156	A673	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.1119060313530787	[470]	[597,629,652,556]	2	hSpCas9	negative selection	5762630
7676381	7676404	17	-	27260156	A673	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.009647804542047653	[452]	[651,493,465,593]	0	hSpCas9	negative selection	5762631
7674219	7674242	17	+	27260156	A375	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.7061734553735908	[847]	[1597,1840,1604,1462]	9	hSpCas9	negative selection	5819631
7675056	7675079	17	+	27260156	A375	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.2766955080036678	[267]	[383,462,346,337]	4	hSpCas9	negative selection	5819632
7676210	7676233	17	-	27260156	A375	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.9858165633182022	[178]	[350,295,292,666]	9	hSpCas9	negative selection	5819633
7675052	7675075	17	-	27260156	A375	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.8397697178527939	[133]	[112,328,430,254]	9	hSpCas9	negative selection	5883880
7676248	7676271	17	-	27260156	A375	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.41149228440102936	[470]	[696,660,880,680]	6	hSpCas9	negative selection	5883881
7676381	7676404	17	-	27260156	A375	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.24597714847744448	[452]	[717,698,639,478]	3	hSpCas9	negative selection	5883882
7674219	7674242	17	+	27260156	COLO741	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.23958412736641677	[847]	[1498,1046,1304]	5	hSpCas9	negative selection	5940882
7675056	7675079	17	+	27260156	COLO741	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.05419434200940909	[267]	[351,454,193]	-1	hSpCas9	negative selection	5940883
7676210	7676233	17	-	27260156	COLO741	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.5048169891825249	[178]	[326,278,363]	8	hSpCas9	negative selection	5940884
7675052	7675075	17	-	27260156	COLO741	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.2369410924728823	[133]	[127,327,146]	5	hSpCas9	negative selection	6005131
7676248	7676271	17	-	27260156	COLO741	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.0928058897870024	[470]	[638,482,574]	-2	hSpCas9	negative selection	6005132
7676381	7676404	17	-	27260156	COLO741	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.191610832132889	[452]	[696,646,641]	4	hSpCas9	negative selection	6005133
7674219	7674242	17	+	27260156	CAL120	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.14004135552099817	[847]	[1358,969,1187]	2	hSpCas9	negative selection	6062133
7675056	7675079	17	+	27260156	CAL120	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.3994951467943725	[267]	[290,212,259]	-5	hSpCas9	negative selection	6062134
7676210	7676233	17	-	27260156	CAL120	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.07867626879179301	[178]	[187,303,206]	1	hSpCas9	negative selection	6062135
7675052	7675075	17	-	27260156	CAL120	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.4941336103962839	[133]	[158,126,75]	-6	hSpCas9	negative selection	6126382
7676248	7676271	17	-	27260156	CAL120	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.24930438448816508	[470]	[622,347,526]	-4	hSpCas9	negative selection	6126383
7676381	7676404	17	-	27260156	CAL120	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.16617646420152274	[452]	[387,698,770]	2	hSpCas9	negative selection	6126384
7674219	7674242	17	+	27260156	CADOES1	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.6332479236607549	[847]	[1186,1384,1063,1258]	9	hSpCas9	negative selection	6183384
7675056	7675079	17	+	27260156	CADOES1	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.25588391941548616	[267]	[222,173,454,339]	4	hSpCas9	negative selection	6183385
7676210	7676233	17	-	27260156	CADOES1	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	1.1933057871891986	[178]	[494,273,430,319]	9	hSpCas9	negative selection	6183386
7675052	7675075	17	-	27260156	CADOES1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.4921022371897539	[133]	[233,115,197,151]	7	hSpCas9	negative selection	6247633
7676248	7676271	17	-	27260156	CADOES1	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.7457229687257415	[470]	[753,939,626,612]	9	hSpCas9	negative selection	6247634
7676381	7676404	17	-	27260156	CADOES1	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.46587861549821996	[452]	[547,553,506,723]	7	hSpCas9	negative selection	6247635
7674219	7674242	17	+	27260156	EWS502	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.42328006177625976	[847]	[1126,1023,1648,1022]	7	hSpCas9	negative selection	6304635
7675056	7675079	17	+	27260156	EWS502	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.4060311022981162	[267]	[337,577,269,306]	7	hSpCas9	negative selection	6304636
7676210	7676233	17	-	27260156	EWS502	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.2523148155324293	[178]	[321,78,163,338]	4	hSpCas9	negative selection	6304637
7675052	7675075	17	-	27260156	EWS502	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.08076225309279383	[133]	[64,99,194,190]	-1	hSpCas9	negative selection	6368884
7676248	7676271	17	-	27260156	EWS502	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.09071405880090994	[470]	[481,562,565,515]	1	hSpCas9	negative selection	6368885
7676381	7676404	17	-	27260156	EWS502	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.13580029718057998	[452]	[471,439,534,680]	2	hSpCas9	negative selection	6368886
7674219	7674242	17	+	27260156	EW8	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.425262599295388	[847]	[968,927,861,944]	7	hSpCas9	negative selection	6425886
7675056	7675079	17	+	27260156	EW8	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.18724106055662737	[267]	[299,168,227,299]	3	hSpCas9	negative selection	6425887
7676210	7676233	17	-	27260156	EW8	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.06139815610432886	[178]	[157,191,139,117]	1	hSpCas9	negative selection	6425888
7675052	7675075	17	-	27260156	EW8	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.12906665096715142	[133]	[146,74,105,72]	-2	hSpCas9	negative selection	6490135
7676248	7676271	17	-	27260156	EW8	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.30425432083844267	[470]	[397,597,372,523]	5	hSpCas9	negative selection	6490136
7676381	7676404	17	-	27260156	EW8	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.2829542196124228	[452]	[528,368,392,511]	5	hSpCas9	negative selection	6490137
7674219	7674242	17	+	27260156	CORL105	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.3913000755187128	[847]	[2338,2379,2661,3036]	9	hSpCas9	negative selection	6547137
7675056	7675079	17	+	27260156	CORL105	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.2725511379789427	[267]	[400,293,447,385]	5	hSpCas9	negative selection	6547138
7676210	7676233	17	-	27260156	CORL105	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	1.9021627620706392	[178]	[742,899,905,599]	9	hSpCas9	negative selection	6547139
7675052	7675075	17	-	27260156	CORL105	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.9437991484725856	[133]	[149,254,477,346]	9	hSpCas9	negative selection	6611386
7676248	7676271	17	-	27260156	CORL105	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	1.0895472986434576	[470]	[1196,1316,1217,966]	9	hSpCas9	negative selection	6611387
7676381	7676404	17	-	27260156	CORL105	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.8026833683361662	[452]	[1152,969,993,601]	9	hSpCas9	negative selection	6611388
7674219	7674242	17	+	27260156	HS294T	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.1749883154661602	[847]	[878,591,565,947]	9	hSpCas9	negative selection	6668388
7675056	7675079	17	+	27260156	HS294T	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.95440793492821	[267]	[120,340,139,203]	9	hSpCas9	negative selection	6668389
7676210	7676233	17	-	27260156	HS294T	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	2.180327679779918	[178]	[435,391,137,264]	9	hSpCas9	negative selection	6668390
7675052	7675075	17	-	27260156	HS294T	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	1.0206783965910327	[133]	[59,109,55,216]	9	hSpCas9	negative selection	6732637
7676248	7676271	17	-	27260156	HS294T	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.9597587878852442	[470]	[199,338,513,382]	9	hSpCas9	negative selection	6732638
7676381	7676404	17	-	27260156	HS294T	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.3340634380910609	[452]	[216,205,180,290]	4	hSpCas9	negative selection	6732639
7674219	7674242	17	+	27260156	HCC44	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.2621612741700634	[847]	[1289,965,1340,1068]	4	hSpCas9	negative selection	6789639
7675056	7675079	17	+	27260156	HCC44	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.22438277166951903	[267]	[473,123,361,493]	3	hSpCas9	negative selection	6789640
7676210	7676233	17	-	27260156	HCC44	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.8008163341685575	[178]	[204,252,755,266]	9	hSpCas9	negative selection	6789641
7675052	7675075	17	-	27260156	HCC44	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.09495825902644706	[133]	[84,137,166,174]	-1	hSpCas9	negative selection	6853888
7676248	7676271	17	-	27260156	HCC44	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.30040580442379194	[470]	[489,712,506,852]	5	hSpCas9	negative selection	6853889
7676381	7676404	17	-	27260156	HCC44	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.04491686035719684	[452]	[448,440,743,397]	0	hSpCas9	negative selection	6853890
7674219	7674242	17	+	27260156	G402	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	2.1538404940485023	[847]	[6286,4740,3789,3869]	9	hSpCas9	negative selection	6910890
7675056	7675079	17	+	27260156	G402	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.6942496972404537	[267]	[581,348,553,621]	8	hSpCas9	negative selection	6910891
7676210	7676233	17	-	27260156	G402	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	4.36603987117466	[178]	[8367,2793,2686,4602]	10	hSpCas9	negative selection	6910892
7675052	7675075	17	-	27260156	G402	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	2.779992822175293	[133]	[1091,1289,1071,1042]	9	hSpCas9	negative selection	6975139
7676248	7676271	17	-	27260156	G402	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	3.5905269977065144	[470]	[5469,3569,8770,9330]	9	hSpCas9	negative selection	6975140
7676381	7676404	17	-	27260156	G402	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	2.7727517047934582	[452]	[3233,3679,3442,4612]	9	hSpCas9	negative selection	6975141
7674219	7674242	17	+	27260156	L33	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.4351487128950964	[847]	[1083,489,712,1172]	8	hSpCas9	negative selection	7032141
7675056	7675079	17	+	27260156	L33	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.04145411778857744	[267]	[200,92,189,373]	0	hSpCas9	negative selection	7032142
7676210	7676233	17	-	27260156	L33	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.17956847143164723	[178]	[179,65,136,251]	4	hSpCas9	negative selection	7032143
7675052	7675075	17	-	27260156	L33	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.16374061709909338	[133]	[144,58,74,69]	-4	hSpCas9	negative selection	7096390
7676248	7676271	17	-	27260156	L33	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.10788412922076555	[470]	[442,219,210,431]	-2	hSpCas9	negative selection	7096391
7676381	7676404	17	-	27260156	L33	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.04005774322044306	[452]	[456,215,268,450]	0	hSpCas9	negative selection	7096392
7674219	7674242	17	+	27260156	K562	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.5120335815494121	[847]	[1075,905,1492,832]	6	hSpCas9	negative selection	7153392
7675056	7675079	17	+	27260156	K562	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.5760198868805895	[267]	[452,119,433,399]	7	hSpCas9	negative selection	7153393
7676210	7676233	17	-	27260156	K562	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.5476746228493082	[178]	[412,229,109,193]	7	hSpCas9	negative selection	7153394
7675052	7675075	17	-	27260156	K562	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.8673829750631219	[133]	[66,125,16,54]	-7	hSpCas9	negative selection	7217641
7676248	7676271	17	-	27260156	K562	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.6118167081131234	[470]	[904,694,922,115]	7	hSpCas9	negative selection	7217642
7676381	7676404	17	-	27260156	K562	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.22055799980049712	[452]	[481,547,548,315]	2	hSpCas9	negative selection	7217643
7674219	7674242	17	+	27260156	HT29	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.3352508484571983	[847]	[1300,1750,1181,1030]	6	hSpCas9	negative selection	7274643
7675056	7675079	17	+	27260156	HT29	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.09983873219604955	[267]	[343,364,297,224]	-2	hSpCas9	negative selection	7274644
7676210	7676233	17	-	27260156	HT29	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.4521762276702487	[178]	[253,264,325,332]	8	hSpCas9	negative selection	7274645
7675052	7675075	17	-	27260156	HT29	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.19219239680152533	[133]	[124,146,186,112]	-4	hSpCas9	negative selection	7338892
7676248	7676271	17	-	27260156	HT29	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.18852952358599115	[470]	[710,611,646,637]	3	hSpCas9	negative selection	7338893
7676381	7676404	17	-	27260156	HT29	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.16573556377320808	[452]	[659,731,555,540]	3	hSpCas9	negative selection	7338894
7674219	7674242	17	+	27260156	MHHES1	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.14609880358189087	[847]	[1169,1340,888,884]	2	hSpCas9	negative selection	7395894
7675056	7675079	17	+	27260156	MHHES1	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.05678286729693194	[267]	[325,323,330,201]	-1	hSpCas9	negative selection	7395895
7676210	7676233	17	-	27260156	MHHES1	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.11635537722203759	[178]	[173,252,148,171]	-2	hSpCas9	negative selection	7395896
7675052	7675075	17	-	27260156	MHHES1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.07996862253332204	[133]	[160,212,97,165]	1	hSpCas9	negative selection	7460143
7676248	7676271	17	-	27260156	MHHES1	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.15004084963223774	[470]	[654,423,529,340]	-3	hSpCas9	negative selection	7460144
7676381	7676404	17	-	27260156	MHHES1	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.27830717916074005	[452]	[651,763,725,391]	5	hSpCas9	negative selection	7460145
7674219	7674242	17	+	27260156	MEWO	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.33660948920889	[847]	[1066,984,965]	7	hSpCas9	negative selection	7517145
7675056	7675079	17	+	27260156	MEWO	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.11225499012707907	[267]	[254,248,305]	2	hSpCas9	negative selection	7517146
7676210	7676233	17	-	27260156	MEWO	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.28471525376053086	[178]	[286,211,128]	6	hSpCas9	negative selection	7517147
7675052	7675075	17	-	27260156	MEWO	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.17291630005205083	[133]	[161,132,132]	4	hSpCas9	negative selection	7581394
7676248	7676271	17	-	27260156	MEWO	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.18652840269802218	[470]	[479,286,412]	-4	hSpCas9	negative selection	7581395
7676381	7676404	17	-	27260156	MEWO	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.11186685067489474	[452]	[479,478,418]	2	hSpCas9	negative selection	7581396
7674219	7674242	17	+	27260156	LNCAPCLONEFGC	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.2042296339427794	[847]	[1471,1811,1960,1864]	9	hSpCas9	negative selection	7638396
7675056	7675079	17	+	27260156	LNCAPCLONEFGC	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.26608735962654717	[267]	[215,345,335,273]	4	hSpCas9	negative selection	7638397
7676210	7676233	17	-	27260156	LNCAPCLONEFGC	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	2.891315440014507	[178]	[924,1034,1607,1319]	9	hSpCas9	negative selection	7638398
7675052	7675075	17	-	27260156	LNCAPCLONEFGC	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	1.5249107336191436	[133]	[411,279,292,406]	9	hSpCas9	negative selection	7702645
7676248	7676271	17	-	27260156	LNCAPCLONEFGC	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	1.2445084458931563	[470]	[1079,995,898,1050]	9	hSpCas9	negative selection	7702646
7676381	7676404	17	-	27260156	LNCAPCLONEFGC	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	1.1799316995378955	[452]	[881,807,907,1125]	9	hSpCas9	negative selection	7702647
7674219	7674242	17	+	27260156	PANC0327	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.5167662085622022	[847]	[1155,964,1227,982]	7	hSpCas9	negative selection	7759647
7675056	7675079	17	+	27260156	PANC0327	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.3151379765417294	[267]	[518,179,307,210]	5	hSpCas9	negative selection	7759648
7676210	7676233	17	-	27260156	PANC0327	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.41963526260826667	[178]	[129,52,185,115]	-6	hSpCas9	negative selection	7759649
7675052	7675075	17	-	27260156	PANC0327	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.8721937602716245	[133]	[38,64,84,68]	-8	hSpCas9	negative selection	7823896
7676248	7676271	17	-	27260156	PANC0327	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.15775579280161475	[470]	[405,332,348,419]	-2	hSpCas9	negative selection	7823897
7676381	7676404	17	-	27260156	PANC0327	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.2022234607734931	[452]	[249,155,512,496]	-3	hSpCas9	negative selection	7823898
7674219	7674242	17	+	27260156	NCIH2009	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.6317411492202072	[847]	[2230,1684,1668]	8	hSpCas9	negative selection	7880898
7675056	7675079	17	+	27260156	NCIH2009	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.212654662654015	[267]	[485,338,487]	3	hSpCas9	negative selection	7880899
7676210	7676233	17	-	27260156	NCIH2009	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.13450050655363643	[178]	[212,126,341]	-2	hSpCas9	negative selection	7880900
7675052	7675075	17	-	27260156	NCIH2009	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.7193580541806481	[133]	[93,60,182]	-7	hSpCas9	negative selection	7945147
7676248	7676271	17	-	27260156	NCIH2009	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.5234198072594053	[470]	[482,384,510]	-6	hSpCas9	negative selection	7945148
7676381	7676404	17	-	27260156	NCIH2009	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.12562334539266995	[452]	[501,357,867]	-2	hSpCas9	negative selection	7945149
7674219	7674242	17	+	27260156	NCIH1373	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.8470616993140707	[847]	[2512,1904,1371,292]	8	hSpCas9	negative selection	8002149
7675056	7675079	17	+	27260156	NCIH1373	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	1.0071316297993345	[267]	[641,684,601,123]	8	hSpCas9	negative selection	8002150
7676210	7676233	17	-	27260156	NCIH1373	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.2757846869826963	[178]	[182,260,153,12]	-3	hSpCas9	negative selection	8002151
7675052	7675075	17	-	27260156	NCIH1373	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.1747140693031093	[133]	[131,24,267,29]	-2	hSpCas9	negative selection	8066398
7676248	7676271	17	-	27260156	NCIH1373	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.06501765523116215	[470]	[263,685,533,123]	0	hSpCas9	negative selection	8066399
7676381	7676404	17	-	27260156	NCIH1373	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.3043584395792845	[452]	[283,270,319,206]	-3	hSpCas9	negative selection	8066400
7674219	7674242	17	+	27260156	PATU8902	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.24017126505158815	[847]	[2231,1166,795,1533]	2	hSpCas9	negative selection	8123400
7675056	7675079	17	+	27260156	PATU8902	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.5225376073842929	[267]	[586,301,141,1301]	5	hSpCas9	negative selection	8123401
7676210	7676233	17	-	27260156	PATU8902	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.18541210318981927	[178]	[257,228,237,436]	1	hSpCas9	negative selection	8123402
7675052	7675075	17	-	27260156	PATU8902	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.24026027581304232	[133]	[114,98,196,216]	-2	hSpCas9	negative selection	8187649
7676248	7676271	17	-	27260156	PATU8902	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.18772520121250177	[470]	[1022,614,724,603]	2	hSpCas9	negative selection	8187650
7676381	7676404	17	-	27260156	PATU8902	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.11258358276200206	[452]	[946,457,542,359]	-1	hSpCas9	negative selection	8187651
7674219	7674242	17	+	27260156	PANC1	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.2589349547856723	[847]	[794,1312,948,559]	4	hSpCas9	negative selection	8244651
7675056	7675079	17	+	27260156	PANC1	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.1501550870552225	[267]	[281,311,205,231]	2	hSpCas9	negative selection	8244652
7676210	7676233	17	-	27260156	PANC1	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.10428058973807164	[178]	[138,205,197,54]	-2	hSpCas9	negative selection	8244653
7675052	7675075	17	-	27260156	PANC1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.05747816967777175	[133]	[80,252,92,52]	-1	hSpCas9	negative selection	8308900
7676248	7676271	17	-	27260156	PANC1	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.18494516351182488	[470]	[432,314,362,304]	-3	hSpCas9	negative selection	8308901
7676381	7676404	17	-	27260156	PANC1	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.17808891708273858	[452]	[377,512,237,283]	-3	hSpCas9	negative selection	8308902
7674219	7674242	17	+	27260156	PANC0813	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.5451555611337431	[847]	[1585,1330,1421,1482]	8	hSpCas9	negative selection	8365902
7675056	7675079	17	+	27260156	PANC0813	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.35017380368576806	[267]	[560,405,395,263]	5	hSpCas9	negative selection	8365903
7676210	7676233	17	-	27260156	PANC0813	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.360161592539022	[178]	[179,149,188,138]	-5	hSpCas9	negative selection	8365904
7675052	7675075	17	-	27260156	PANC0813	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.5267795074774995	[133]	[103,93,69,164]	-7	hSpCas9	negative selection	8430151
7676248	7676271	17	-	27260156	PANC0813	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.04410090858356378	[470]	[420,519,461,720]	0	hSpCas9	negative selection	8430152
7676381	7676404	17	-	27260156	PANC0813	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	-0.016457764563068834	[452]	[510,459,545,581]	0	hSpCas9	negative selection	8430153
7674219	7674242	17	+	27260156	RDES	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.5799835510717335	[847]	[1166,1494,1758,1431]	8	hSpCas9	negative selection	8487153
7675056	7675079	17	+	27260156	RDES	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.29136499346509825	[267]	[283,437,265,544]	5	hSpCas9	negative selection	8487154
7676210	7676233	17	-	27260156	RDES	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.2904515210311236	[178]	[172,319,261,255]	5	hSpCas9	negative selection	8487155
7675052	7675075	17	-	27260156	RDES	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.2545624085411544	[133]	[150,197,195,191]	4	hSpCas9	negative selection	8551402
7676248	7676271	17	-	27260156	RDES	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.05680878356063487	[470]	[463,592,536,676]	0	hSpCas9	negative selection	8551403
7676381	7676404	17	-	27260156	RDES	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.21742897944797415	[452]	[404,540,907,614]	3	hSpCas9	negative selection	8551404
7674219	7674242	17	+	27260156	PC3	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	-0.020856105198639896	[847]	[622,669,1294,935]	0	hSpCas9	negative selection	8608404
7675056	7675079	17	+	27260156	PC3	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.12585336514269396	[267]	[168,283,372,205]	-3	hSpCas9	negative selection	8608405
7676210	7676233	17	-	27260156	PC3	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.11704490450741822	[178]	[180,61,180,214]	-3	hSpCas9	negative selection	8608406
7675052	7675075	17	-	27260156	PC3	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.1543280998976917	[133]	[124,66,261,182]	3	hSpCas9	negative selection	8672653
7676248	7676271	17	-	27260156	PC3	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.04078817275894302	[470]	[313,447,824,393]	-1	hSpCas9	negative selection	8672654
7676381	7676404	17	-	27260156	PC3	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.12091000036099978	[452]	[243,429,806,687]	2	hSpCas9	negative selection	8672655
7674219	7674242	17	+	27260156	PATU8988T	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.609814266871946	[847]	[1151,1132,1265,1455]	8	hSpCas9	negative selection	8729655
7675056	7675079	17	+	27260156	PATU8988T	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.14165889842542867	[267]	[185,260,171,330]	-2	hSpCas9	negative selection	8729656
7676210	7676233	17	-	27260156	PATU8988T	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.25843178701753855	[178]	[345,168,195,104]	4	hSpCas9	negative selection	8729657
7675052	7675075	17	-	27260156	PATU8988T	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.31044176397385725	[133]	[87,310,128,125]	5	hSpCas9	negative selection	8793904
7676248	7676271	17	-	27260156	PATU8988T	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.27760250851207785	[470]	[445,538,538,692]	5	hSpCas9	negative selection	8793905
7676381	7676404	17	-	27260156	PATU8988T	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.19386139595291768	[452]	[551,398,575,461]	3	hSpCas9	negative selection	8793906
7674219	7674242	17	+	27260156	T47D	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.3706082263462558	[847]	[1317,1103,1393,1306]	7	hSpCas9	negative selection	8850906
7675056	7675079	17	+	27260156	T47D	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.22262206996683698	[267]	[401,306,365,387]	5	hSpCas9	negative selection	8850907
7676210	7676233	17	-	27260156	T47D	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.48504110556831537	[178]	[364,222,306,277]	8	hSpCas9	negative selection	8850908
7675052	7675075	17	-	27260156	T47D	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.2696249084756934	[133]	[216,114,225,200]	6	hSpCas9	negative selection	8915155
7676248	7676271	17	-	27260156	T47D	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.21122710809870468	[470]	[626,642,552,720]	4	hSpCas9	negative selection	8915156
7676381	7676404	17	-	27260156	T47D	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.20252738753854357	[452]	[670,575,645,535]	4	hSpCas9	negative selection	8915157
7674219	7674242	17	+	27260156	SU8686	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.4323602041883303	[847]	[1020,946,1134,1527]	7	hSpCas9	negative selection	8972157
7675056	7675079	17	+	27260156	SU8686	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.3544188275762217	[267]	[236,258,469,430]	6	hSpCas9	negative selection	8972158
7676210	7676233	17	-	27260156	SU8686	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.7864417005177444	[178]	[316,182,368,381]	9	hSpCas9	negative selection	8972159
7675052	7675075	17	-	27260156	SU8686	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.6595702189345705	[133]	[248,161,186,246]	9	hSpCas9	negative selection	9036406
7676248	7676271	17	-	27260156	SU8686	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.40981513393920854	[470]	[501,721,641,609]	7	hSpCas9	negative selection	9036407
7676381	7676404	17	-	27260156	SU8686	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.22920565970093273	[452]	[553,493,403,670]	4	hSpCas9	negative selection	9036408
7674219	7674242	17	+	27260156	SKES1	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.3845133664932159	[847]	[1110,1635,940,818]	7	hSpCas9	negative selection	9093408
7675056	7675079	17	+	27260156	SKES1	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.06918861801458531	[267]	[310,314,251,252]	1	hSpCas9	negative selection	9093409
7676210	7676233	17	-	27260156	SKES1	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.07223796500392798	[178]	[86,306,116,171]	-1	hSpCas9	negative selection	9093410
7675052	7675075	17	-	27260156	SKES1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.11471540636453925	[133]	[44,182,168,167]	2	hSpCas9	negative selection	9157657
7676248	7676271	17	-	27260156	SKES1	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.010258852630533903	[470]	[470,623,428,391]	0	hSpCas9	negative selection	9157658
7676381	7676404	17	-	27260156	SKES1	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.13527653652064894	[452]	[543,573,565,330]	3	hSpCas9	negative selection	9157659
7674219	7674242	17	+	27260156	TOV112D	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.45037470153815384	[847]	[1444,1378,957,941]	8	hSpCas9	negative selection	9214659
7675056	7675079	17	+	27260156	TOV112D	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.02439905990692215	[267]	[239,358,227,249]	0	hSpCas9	negative selection	9214660
7676210	7676233	17	-	27260156	TOV112D	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	-0.258629939959621	[178]	[193,141,152,112]	-5	hSpCas9	negative selection	9214661
7675052	7675075	17	-	27260156	TOV112D	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.8223506058123146	[133]	[292,169,127,342]	9	hSpCas9	negative selection	9278908
7676248	7676271	17	-	27260156	TOV112D	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.09692836221643432	[470]	[422,591,552,464]	2	hSpCas9	negative selection	9278909
7676381	7676404	17	-	27260156	TOV112D	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.12066162109623454	[452]	[778,447,401,359]	2	hSpCas9	negative selection	9278910
7674219	7674242	17	+	27260156	TC71	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	0.1781246664173035	[847]	[845,1009,1050,1221]	4	hSpCas9	negative selection	9335910
7675056	7675079	17	+	27260156	TC71	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	-0.18156516693829772	[267]	[204,236,298,272]	-5	hSpCas9	negative selection	9335911
7676210	7676233	17	-	27260156	TC71	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	0.2919322306243879	[178]	[290,190,199,258]	7	hSpCas9	negative selection	9335912
7675052	7675075	17	-	27260156	TC71	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.2739218074021954	[133]	[84,61,147,183]	-6	hSpCas9	negative selection	9400159
7676248	7676271	17	-	27260156	TC71	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	-0.15629588032205577	[470]	[428,452,445,486]	-4	hSpCas9	negative selection	9400160
7676381	7676404	17	-	27260156	TC71	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.1748629295834429	[452]	[521,422,638,609]	4	hSpCas9	negative selection	9400161
7674219	7674242	17	+	27260156	TC32	viability	CCGGTTCATGCCGCCCATGCAGG	TP53	ENSG00000141510	1.0305758986044946	[847]	[1764,1163,1551,2102]	9	hSpCas9	negative selection	9457161
7675056	7675079	17	+	27260156	TC32	viability	CGCTATCTGAGCAGCGCTCATGG	TP53	ENSG00000141510	0.018963340342926127	[267]	[238,160,311,346]	0	hSpCas9	negative selection	9457162
7676210	7676233	17	-	27260156	TC32	viability	CCCCGGACGATATTGAACAATGG	TP53	ENSG00000141510	1.4425044081356486	[178]	[487,336,621,421]	9	hSpCas9	negative selection	9457163
7675052	7675075	17	-	27260156	TC32	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.9052928215273958	[133]	[202,201,331,224]	9	hSpCas9	negative selection	9521410
7676248	7676271	17	-	27260156	TC32	viability	CCCCTTGCCGTCCCAAGCAATGG	TP53	ENSG00000141510	0.8105592248899268	[470]	[707,635,1018,799]	9	hSpCas9	negative selection	9521411
7676381	7676404	17	-	27260156	TC32	viability	ACTTCCTGAAAACAACGTTCTGG	TP53	ENSG00000141510	0.5125072965994215	[452]	[632,466,823,551]	8	hSpCas9	negative selection	9521412
7673558	7673581	17	-	27869803	HPAFII	viability after 27 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	-0.19250062305441362	[427]	[233,165,NaN]	-1	hSpCas9	negative selection	9563320
7673742	7673765	17	-	27869803	HPAFII	viability after 27 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.5452250587570472	[245]	[149,220,NaN]	4	hSpCas9	negative selection	9563321
7674216	7674239	17	-	27869803	HPAFII	viability after 27 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.22760223660905704	[311]	[234,60,NaN]	-2	hSpCas9	negative selection	9563322
7674939	7674962	17	-	27869803	HPAFII	viability after 27 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-1.0453450589255602	[858]	[292,156,NaN]	-6	hSpCas9	negative selection	9563323
7675114	7675137	17	+	27869803	HPAFII	viability after 27 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.42857709983679604	[230]	[175,152,NaN]	3	hSpCas9	negative selection	9563324
7676020	7676043	17	+	27869803	HPAFII	viability after 27 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	0.47187512719668995	[144]	[48,152,NaN]	4	hSpCas9	negative selection	9563325
7673558	7673581	17	-	27869803	HPAFII	viability after 15 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	-0.005797886238949168	[427]	[697,308,NaN]	0	hSpCas9	negative selection	9645769
7673742	7673765	17	-	27869803	HPAFII	viability after 15 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.5020812670679761	[245]	[387,365,NaN]	6	hSpCas9	negative selection	9645770
7674216	7674239	17	-	27869803	HPAFII	viability after 15 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.19087506038537963	[311]	[413,218,NaN]	-2	hSpCas9	negative selection	9645771
7674939	7674962	17	-	27869803	HPAFII	viability after 15 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.5963822836132187	[858]	[884,439,NaN]	-6	hSpCas9	negative selection	9645772
7675114	7675137	17	+	27869803	HPAFII	viability after 15 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.3734192928703256	[230]	[365,293,NaN]	4	hSpCas9	negative selection	9645773
7676020	7676043	17	+	27869803	HPAFII	viability after 15 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.1599082446098199	[144]	[165,122,NaN]	-2	hSpCas9	negative selection	9645774
7673558	7673581	17	-	27869803	ASPC1	viability after 36 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.3406469617009076	[843]	[125,573,382]	3	hSpCas9	negative selection	9728218
7673742	7673765	17	-	27869803	ASPC1	viability after 36 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	1.2780332309387563	[555]	[532,350,516]	9	hSpCas9	negative selection	9728219
7674216	7674239	17	-	27869803	ASPC1	viability after 36 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.34655088823992486	[709]	[532,202,247]	3	hSpCas9	negative selection	9728220
7674939	7674962	17	-	27869803	ASPC1	viability after 36 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.12773371678815137	[2095]	[1009,383,972]	1	hSpCas9	negative selection	9728221
7675114	7675137	17	+	27869803	ASPC1	viability after 36 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.0354352313731684	[734]	[505,322,41]	0	hSpCas9	negative selection	9728222
7676020	7676043	17	+	27869803	ASPC1	viability after 36 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.8414072710892679	[328]	[97,45,53]	-7	hSpCas9	negative selection	9728223
7673558	7673581	17	-	27869803	PATU8988S	viability after 35 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	1.021810892607784	[770]	[849,409,NaN]	9	hSpCas9	negative selection	9810667
7673742	7673765	17	-	27869803	PATU8988S	viability after 35 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.27153991379832565	[547]	[228,303,NaN]	3	hSpCas9	negative selection	9810668
7674216	7674239	17	-	27869803	PATU8988S	viability after 35 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.7915584611773058	[666]	[460,468,NaN]	8	hSpCas9	negative selection	9810669
7674939	7674962	17	-	27869803	PATU8988S	viability after 35 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	1.0624514703927912	[1847]	[1736,1370,NaN]	9	hSpCas9	negative selection	9810670
7675114	7675137	17	+	27869803	PATU8988S	viability after 35 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.732466267501419	[728]	[626,347,NaN]	7	hSpCas9	negative selection	9810671
7676020	7676043	17	+	27869803	PATU8988S	viability after 35 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	1.2008286170255622	[306]	[381,185,NaN]	9	hSpCas9	negative selection	9810672
7673558	7673581	17	-	27869803	PATU8988S	viability after 31 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.6996347203428543	[770]	[581,393,NaN]	7	hSpCas9	negative selection	9893116
7673742	7673765	17	-	27869803	PATU8988S	viability after 31 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.40136713227513615	[547]	[292,282,NaN]	5	hSpCas9	negative selection	9893117
7674216	7674239	17	-	27869803	PATU8988S	viability after 31 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.8832836531658107	[666]	[417,582,NaN]	8	hSpCas9	negative selection	9893118
7674939	7674962	17	-	27869803	PATU8988S	viability after 31 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	0.7535073531388576	[1847]	[1108,1411,NaN]	8	hSpCas9	negative selection	9893119
7675114	7675137	17	+	27869803	PATU8988S	viability after 31 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	0.5451911961814271	[728]	[472,361,NaN]	6	hSpCas9	negative selection	9893120
7676020	7676043	17	+	27869803	PATU8988S	viability after 31 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	1.0310592594981607	[306]	[232,271,NaN]	9	hSpCas9	negative selection	9893121
7673558	7673581	17	-	27869803	HPAFII	viability after 35 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	-0.21617845707457684	[427]	[170,203,NaN]	-1	hSpCas9	negative selection	9975565
7673742	7673765	17	-	27869803	HPAFII	viability after 35 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.255869397635942	[245]	[143,153,NaN]	1	hSpCas9	negative selection	9975566
7674216	7674239	17	-	27869803	HPAFII	viability after 35 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.42386359834758935	[311]	[184,41,NaN]	-3	hSpCas9	negative selection	9975567
7674939	7674962	17	-	27869803	HPAFII	viability after 35 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-1.1837761713703112	[858]	[221,156,NaN]	-6	hSpCas9	negative selection	9975568
7675114	7675137	17	+	27869803	HPAFII	viability after 35 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	1.0463015308311858	[230]	[328,142,NaN]	7	hSpCas9	negative selection	9975569
7676020	7676043	17	+	27869803	HPAFII	viability after 35 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	0.43889004606893994	[144]	[51,152,NaN]	3	hSpCas9	negative selection	9975570
7673558	7673581	17	-	27869803	HPAFII	viability after 31 days	CCAGCCAAAGAAGAAACCACTGG	TP53	ENSG00000141510	0.03462815391035612	[427]	[257,232,NaN]	0	hSpCas9	negative selection	10058014
7673742	7673765	17	-	27869803	HPAFII	viability after 31 days	GAAGAGAATCTCCGCAAGAAAGG	TP53	ENSG00000141510	0.15422650924320525	[245]	[111,198,NaN]	1	hSpCas9	negative selection	10058015
7674216	7674239	17	-	27869803	HPAFII	viability after 31 days	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.39969586773613786	[311]	[215,41,NaN]	-3	hSpCas9	negative selection	10058016
7674939	7674962	17	-	27869803	HPAFII	viability after 31 days	TCCTCAGCATCTTATCCGAGTGG	TP53	ENSG00000141510	-0.776737845659597	[858]	[356,198,NaN]	-5	hSpCas9	negative selection	10058017
7675114	7675137	17	+	27869803	HPAFII	viability after 31 days	TGACTGCTTGTAGATGGCCATGG	TP53	ENSG00000141510	1.186787025738278	[230]	[308,279,NaN]	8	hSpCas9	negative selection	10058018
7676020	7676043	17	+	27869803	HPAFII	viability after 31 days	CAGAATGCAAGAAGCCCAGACGG	TP53	ENSG00000141510	-0.018696575743839317	[144]	[42,120,NaN]	0	hSpCas9	negative selection	10058019
7676073	7676096	17	+	28162770	P31FUJ	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.9716402129133557	[256]	[76]	-8	hSpCas9	negative selection	10255446
7673740	7673763	17	-	28162770	P31FUJ	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.8780913870978452	[193]	[418]	8	hSpCas9	negative selection	10255447
7675098	7675121	17	-	28162770	P31FUJ	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.2399507927207526	[195]	[271]	2	hSpCas9	negative selection	10255448
7674216	7674239	17	-	28162770	P31FUJ	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.2791578401061181	[252]	[244]	-3	hSpCas9	negative selection	10255449
7675052	7675075	17	-	28162770	P31FUJ	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.17055348981682986	[216]	[286]	1	hSpCas9	negative selection	10255450
7676510	7676533	17	+	28162770	P31FUJ	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.1557407412547671	[564]	[595]	-1	hSpCas9	negative selection	10255451
7675166	7675189	17	+	28162770	P31FUJ	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.7939179631811668	[89]	[60]	-6	hSpCas9	negative selection	10255452
7674845	7674868	17	+	28162770	P31FUJ	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-0.07410445839532032	[85]	[95]	0	hSpCas9	negative selection	10255453
7673819	7673842	17	-	28162770	P31FUJ	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	1.0111233784717106	[37]	[89]	9	hSpCas9	negative selection	10255454
7673764	7673787	17	-	28162770	P31FUJ	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	1.1858019098846577	[201]	[539]	9	hSpCas9	negative selection	10255455
7676073	7676096	17	+	28162770	TF1	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10424812
7673740	7673763	17	-	28162770	TF1	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10424813
7675098	7675121	17	-	28162770	TF1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10424814
7674216	7674239	17	-	28162770	TF1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10424815
7675052	7675075	17	-	28162770	TF1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10424816
7676510	7676533	17	+	28162770	TF1	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10424817
7675166	7675189	17	+	28162770	TF1	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10424818
7674845	7674868	17	+	28162770	TF1	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10424819
7673819	7673842	17	-	28162770	TF1	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10424820
7673764	7673787	17	-	28162770	TF1	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	NaN	[NaN]	[437]	1	hSpCas9	negative selection	10424821
7676073	7676096	17	+	28162770	SKM1	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-0.8526984952449218	[94]	[92]	-6	hSpCas9	negative selection	10594178
7673740	7673763	17	-	28162770	SKM1	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.2719744501870081	[51]	[110]	2	hSpCas9	negative selection	10594179
7675098	7675121	17	-	28162770	SKM1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.9263383578367412	[85]	[79]	-6	hSpCas9	negative selection	10594180
7674216	7674239	17	-	28162770	SKM1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.10957828811859094	[82]	[135]	-1	hSpCas9	negative selection	10594181
7675052	7675075	17	-	28162770	SKM1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.3625700793847083	[63]	[87]	-3	hSpCas9	negative selection	10594182
7676510	7676533	17	+	28162770	SKM1	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.023865305993779895	[156]	[272]	0	hSpCas9	negative selection	10594183
7675166	7675189	17	+	28162770	SKM1	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	0.3155018257279294	[19]	[43]	3	hSpCas9	negative selection	10594184
7674845	7674868	17	+	28162770	SKM1	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-1.9000042100232788	[18]	[8]	-8	hSpCas9	negative selection	10594185
7673819	7673842	17	-	28162770	SKM1	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	2.523773138819725	[5]	[60]	9	hSpCas9	negative selection	10594186
7673764	7673787	17	-	28162770	SKM1	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	-0.7730920975410592	[57]	[59]	-5	hSpCas9	negative selection	10594187
7676073	7676096	17	+	28162770	SKM1	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-0.8526984952449218	[94]	[92]	-6	hSpCas9	negative selection	10763544
7673740	7673763	17	-	28162770	SKM1	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.2719744501870081	[51]	[110]	2	hSpCas9	negative selection	10763545
7675098	7675121	17	-	28162770	SKM1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	-0.9263383578367412	[85]	[79]	-6	hSpCas9	negative selection	10763546
7674216	7674239	17	-	28162770	SKM1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.10957828811859094	[82]	[135]	-1	hSpCas9	negative selection	10763547
7675052	7675075	17	-	28162770	SKM1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-0.3625700793847083	[63]	[87]	-3	hSpCas9	negative selection	10763548
7676510	7676533	17	+	28162770	SKM1	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.023865305993779895	[156]	[272]	0	hSpCas9	negative selection	10763549
7675166	7675189	17	+	28162770	SKM1	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	0.3155018257279294	[19]	[43]	3	hSpCas9	negative selection	10763550
7674845	7674868	17	+	28162770	SKM1	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-1.9000042100232788	[18]	[8]	-8	hSpCas9	negative selection	10763551
7673819	7673842	17	-	28162770	SKM1	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	2.523773138819725	[5]	[60]	9	hSpCas9	negative selection	10763552
7673764	7673787	17	-	28162770	SKM1	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	-0.7730920975410592	[57]	[59]	-5	hSpCas9	negative selection	10763553
7676073	7676096	17	+	28162770	PL21	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.086599051935742	[404]	[82]	-6	hSpCas9	negative selection	10932910
7673740	7673763	17	-	28162770	PL21	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	-0.21736614038027335	[194]	[72]	-1	hSpCas9	negative selection	10932911
7675098	7675121	17	-	28162770	PL21	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	1.1864646775922438	[211]	[209]	8	hSpCas9	negative selection	10932912
7674216	7674239	17	-	28162770	PL21	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.20013961448932016	[257]	[128]	1	hSpCas9	negative selection	10932913
7675052	7675075	17	-	28162770	PL21	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	-1.297766151962613	[208]	[36]	-7	hSpCas9	negative selection	10932914
7676510	7676533	17	+	28162770	PL21	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.43189704735575307	[622]	[200]	-3	hSpCas9	negative selection	10932915
7675166	7675189	17	+	28162770	PL21	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	0.6040365561629636	[64]	[42]	5	hSpCas9	negative selection	10932916
7674845	7674868	17	+	28162770	PL21	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	0.20013961448932016	[49]	[24]	1	hSpCas9	negative selection	10932917
7673819	7673842	17	-	28162770	PL21	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	-2.2148978847895244	[31]	[2]	-8	hSpCas9	negative selection	10932918
7673764	7673787	17	-	28162770	PL21	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	-0.1431621311906091	[169]	[66]	-1	hSpCas9	negative selection	10932919
7676073	7676096	17	+	28162770	P31FUJ	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.9716402129133557	[256]	[76]	-8	hSpCas9	negative selection	11102276
7673740	7673763	17	-	28162770	P31FUJ	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.8780913870978452	[193]	[418]	8	hSpCas9	negative selection	11102277
7675098	7675121	17	-	28162770	P31FUJ	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.2399507927207526	[195]	[271]	2	hSpCas9	negative selection	11102278
7674216	7674239	17	-	28162770	P31FUJ	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.2791578401061181	[252]	[244]	-3	hSpCas9	negative selection	11102279
7675052	7675075	17	-	28162770	P31FUJ	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.17055348981682986	[216]	[286]	1	hSpCas9	negative selection	11102280
7676510	7676533	17	+	28162770	P31FUJ	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.1557407412547671	[564]	[595]	-1	hSpCas9	negative selection	11102281
7675166	7675189	17	+	28162770	P31FUJ	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.7939179631811668	[89]	[60]	-6	hSpCas9	negative selection	11102282
7674845	7674868	17	+	28162770	P31FUJ	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-0.07410445839532032	[85]	[95]	0	hSpCas9	negative selection	11102283
7673819	7673842	17	-	28162770	P31FUJ	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	1.0111233784717106	[37]	[89]	9	hSpCas9	negative selection	11102284
7673764	7673787	17	-	28162770	P31FUJ	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	1.1858019098846577	[201]	[539]	9	hSpCas9	negative selection	11102285
7676073	7676096	17	+	28162770	OCIAML5	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.07542092935163497	[152]	[290]	0	hSpCas9	negative selection	11271642
7673740	7673763	17	-	28162770	OCIAML5	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	2.182506577683429	[133]	[1097]	9	hSpCas9	negative selection	11271643
7675098	7675121	17	-	28162770	OCIAML5	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	1.316575464694842	[124]	[561]	9	hSpCas9	negative selection	11271644
7674216	7674239	17	-	28162770	OCIAML5	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.5660242523924007	[176]	[472]	5	hSpCas9	negative selection	11271645
7675052	7675075	17	-	28162770	OCIAML5	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.9113271485798543	[118]	[403]	7	hSpCas9	negative selection	11271646
7676510	7676533	17	+	28162770	OCIAML5	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.5358590827976055	[281]	[737]	4	hSpCas9	negative selection	11271647
7675166	7675189	17	+	28162770	OCIAML5	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	2.047109059616516	[49]	[372]	9	hSpCas9	negative selection	11271648
7674845	7674868	17	+	28162770	OCIAML5	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	1.260996093622639	[45]	[198]	9	hSpCas9	negative selection	11271649
7673819	7673842	17	-	28162770	OCIAML5	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	2.4537418586600883	[17]	[177]	9	hSpCas9	negative selection	11271650
7673764	7673787	17	-	28162770	OCIAML5	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	2.232306986463102	[109]	[932]	9	hSpCas9	negative selection	11271651
7676073	7676096	17	+	28162770	EOL1	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	1.7869259892819962	[609]	[1108]	9	hSpCas9	negative selection	11441008
7673740	7673763	17	-	28162770	EOL1	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	3.0137001493073168	[250]	[1067]	9	hSpCas9	negative selection	11441009
7675098	7675121	17	-	28162770	EOL1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	2.943489335223995	[453]	[1839]	9	hSpCas9	negative selection	11441010
7674216	7674239	17	-	28162770	EOL1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	3.39789828167378	[496]	[2759]	9	hSpCas9	negative selection	11441011
7675052	7675075	17	-	28162770	EOL1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	2.885791728088042	[414]	[1615]	9	hSpCas9	negative selection	11441012
7676510	7676533	17	+	28162770	EOL1	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.5526678547078199	[954]	[737]	5	hSpCas9	negative selection	11441013
7675166	7675189	17	+	28162770	EOL1	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	3.668413867642751	[72]	[488]	9	hSpCas9	negative selection	11441014
7674845	7674868	17	+	28162770	EOL1	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	3.8694062173780734	[69]	[538]	9	hSpCas9	negative selection	11441015
7673819	7673842	17	-	28162770	EOL1	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	3.4315077602904176	[37]	[215]	9	hSpCas9	negative selection	11441016
7673764	7673787	17	-	28162770	EOL1	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	3.9356029600795304	[194]	[1571]	9	hSpCas9	negative selection	11441017
7676073	7676096	17	+	28162770	MOLM13	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	1.8865052911926723	[452]	[1210]	9	hSpCas9	negative selection	11610374
7673740	7673763	17	-	28162770	MOLM13	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	2.1936102185431623	[321]	[1064]	9	hSpCas9	negative selection	11610375
7675098	7675121	17	-	28162770	MOLM13	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	2.8206784401367018	[369]	[1889]	9	hSpCas9	negative selection	11610376
7674216	7674239	17	-	28162770	MOLM13	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.771751291716634	[449]	[2221]	9	hSpCas9	negative selection	11610377
7675052	7675075	17	-	28162770	MOLM13	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	2.896567791492809	[249]	[1345]	9	hSpCas9	negative selection	11610378
7676510	7676533	17	+	28162770	MOLM13	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.34725967635903987	[934]	[859]	2	hSpCas9	negative selection	11610379
7675166	7675189	17	+	28162770	MOLM13	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	2.9784790404558397	[135]	[774]	9	hSpCas9	negative selection	11610380
7674845	7674868	17	+	28162770	MOLM13	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	1.4263102777931795	[87]	[170]	9	hSpCas9	negative selection	11610381
7673819	7673842	17	-	28162770	MOLM13	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	3.147630107017835	[26]	[172]	9	hSpCas9	negative selection	11610382
7673764	7673787	17	-	28162770	MOLM13	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	2.870475139777166	[239]	[1268]	9	hSpCas9	negative selection	11610383
7676073	7676096	17	+	28162770	HEL	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-1.1301277136719565	[433]	[126]	-6	hSpCas9	negative selection	11779740
7673740	7673763	17	-	28162770	HEL	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.30325236572868997	[247]	[195]	2	hSpCas9	negative selection	11779741
7675098	7675121	17	-	28162770	HEL	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.44479945438844803	[272]	[237]	4	hSpCas9	negative selection	11779742
7674216	7674239	17	-	28162770	HEL	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.7219309994173462	[318]	[336]	6	hSpCas9	negative selection	11779743
7675052	7675075	17	-	28162770	HEL	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.579774874336055	[280]	[268]	5	hSpCas9	negative selection	11779744
7676510	7676533	17	+	28162770	HEL	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.09422676216584924	[839]	[503]	0	hSpCas9	negative selection	11779745
7675166	7675189	17	+	28162770	HEL	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.4336120541297579	[96]	[45]	-3	hSpCas9	negative selection	11779746
7674845	7674868	17	+	28162770	HEL	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-0.6426633868618914	[77]	[31]	-4	hSpCas9	negative selection	11779747
7673819	7673842	17	-	28162770	HEL	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	0.8568636373532044	[49]	[57]	7	hSpCas9	negative selection	11779748
7673764	7673787	17	-	28162770	HEL	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	0.857105112797887	[205]	[238]	7	hSpCas9	negative selection	11779749
7676073	7676096	17	+	28162770	MV411	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	-0.18202701913134822	[267]	[198]	-1	hSpCas9	negative selection	11949106
7673740	7673763	17	-	28162770	MV411	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	1.2937312030567103	[183]	[379]	9	hSpCas9	negative selection	11949107
7675098	7675121	17	-	28162770	MV411	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	1.2987844307829959	[275]	[571]	9	hSpCas9	negative selection	11949108
7674216	7674239	17	-	28162770	MV411	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	2.4587959218442466	[224]	[1041]	9	hSpCas9	negative selection	11949109
7675052	7675075	17	-	28162770	MV411	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	2.3012303681434787	[203]	[846]	9	hSpCas9	negative selection	11949110
7676510	7676533	17	+	28162770	MV411	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.3978082403866108	[618]	[686]	3	hSpCas9	negative selection	11949111
7675166	7675189	17	+	28162770	MV411	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	1.5813382873362136	[47]	[120]	9	hSpCas9	negative selection	11949112
7674845	7674868	17	+	28162770	MV411	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	2.247437550782775	[46]	[187]	9	hSpCas9	negative selection	11949113
7673819	7673842	17	-	28162770	MV411	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	2.0152641086537417	[36]	[125]	9	hSpCas9	negative selection	11949114
7673764	7673787	17	-	28162770	MV411	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	2.4720208533920336	[140]	[658]	9	hSpCas9	negative selection	11949115
7676073	7676096	17	+	28162770	MONOMAC1	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.33474561580242757	[174]	[252]	3	hSpCas9	negative selection	12118472
7673740	7673763	17	-	28162770	MONOMAC1	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.20237000050552578	[115]	[152]	2	hSpCas9	negative selection	12118473
7675098	7675121	17	-	28162770	MONOMAC1	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	1.2039840738379897	[180]	[477]	9	hSpCas9	negative selection	12118474
7674216	7674239	17	-	28162770	MONOMAC1	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	-0.056174311219704065	[194]	[214]	0	hSpCas9	negative selection	12118475
7675052	7675075	17	-	28162770	MONOMAC1	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.7367294545403597	[155]	[297]	7	hSpCas9	negative selection	12118476
7676510	7676533	17	+	28162770	MONOMAC1	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	0.06286466928927736	[460]	[551]	0	hSpCas9	negative selection	12118477
7675166	7675189	17	+	28162770	MONOMAC1	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.4600712528933475	[47]	[39]	-4	hSpCas9	negative selection	12118478
7674845	7674868	17	+	28162770	MONOMAC1	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	-2.5893542698383145	[41]	[7]	-9	hSpCas9	negative selection	12118479
7673819	7673842	17	-	28162770	MONOMAC1	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	0.5254291774115374	[19]	[32]	5	hSpCas9	negative selection	12118480
7673764	7673787	17	-	28162770	MONOMAC1	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	0.7088409755758963	[94]	[177]	6	hSpCas9	negative selection	12118481
7676073	7676096	17	+	28162770	OCIAML2	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	2.1404597031943497	[56]	[1392]	9	hSpCas9	negative selection	12287838
7673740	7673763	17	-	28162770	OCIAML2	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	2.1989639259461717	[39]	[1017]	9	hSpCas9	negative selection	12287839
7675098	7675121	17	-	28162770	OCIAML2	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	2.7904430642583464	[45]	[1763]	9	hSpCas9	negative selection	12287840
7674216	7674239	17	-	28162770	OCIAML2	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	3.3628225335178463	[44]	[2565]	9	hSpCas9	negative selection	12287841
7675052	7675075	17	-	28162770	OCIAML2	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	2.9216875975365992	[31]	[1343]	9	hSpCas9	negative selection	12287842
7676510	7676533	17	+	28162770	OCIAML2	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	1.2520367267212105	[108]	[1438]	9	hSpCas9	negative selection	12287843
7675166	7675189	17	+	28162770	OCIAML2	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	2.494266373801923	[12]	[405]	9	hSpCas9	negative selection	12287844
7674845	7674868	17	+	28162770	OCIAML2	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	1.7978590106837407	[10]	[211]	9	hSpCas9	negative selection	12287845
7673819	7673842	17	-	28162770	OCIAML2	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	3.6723281285998817	[2]	[211]	9	hSpCas9	negative selection	12287846
7673764	7673787	17	-	28162770	OCIAML2	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	3.165335578913098	[32]	[1640]	9	hSpCas9	negative selection	12287847
7676073	7676096	17	+	28162770	OCIAML3	viability	GAAGGGACAGAAGATGACAGGGG	TP53	ENSG00000141510	0.7370998813375946	[93]	[472]	6	hSpCas9	negative selection	12457204
7673740	7673763	17	-	28162770	OCIAML3	viability	AGAGAATCTCCGCAAGAAAGGGG	TP53	ENSG00000141510	0.33465357795557443	[56]	[216]	3	hSpCas9	negative selection	12457205
7675098	7675121	17	-	28162770	OCIAML3	viability	GCAGTCACAGCACATGACGGAGG	TP53	ENSG00000141510	0.6548129062899296	[84]	[403]	6	hSpCas9	negative selection	12457206
7674216	7674239	17	-	28162770	OCIAML3	viability	GCATGGGCGGCATGAACCGGAGG	TP53	ENSG00000141510	0.6744811956017389	[65]	[317]	6	hSpCas9	negative selection	12457207
7675052	7675075	17	-	28162770	OCIAML3	viability	GAGCGCTGCTCAGATAGCGATGG	TP53	ENSG00000141510	0.5180508668683086	[64]	[280]	5	hSpCas9	negative selection	12457208
7676510	7676533	17	+	28162770	OCIAML3	viability	GATCCACTCACAGTTTCCATAGG	TP53	ENSG00000141510	-0.8413887818464715	[164]	[277]	-6	hSpCas9	negative selection	12457209
7675166	7675189	17	+	28162770	OCIAML3	viability	GAATCAACCCACAGCTGCACAGG	TP53	ENSG00000141510	-0.6398113299372878	[31]	[61]	-5	hSpCas9	negative selection	12457210
7674845	7674868	17	+	28162770	OCIAML3	viability	GTTGCAAACCAGACCTCAGGCGG	TP53	ENSG00000141510	0.44161626940655774	[9]	[40]	4	hSpCas9	negative selection	12457211
7673819	7673842	17	-	28162770	OCIAML3	viability	GTAGTGGTAATCTACTGGGACGG	TP53	ENSG00000141510	1.6256703963152488	[18]	[176]	9	hSpCas9	negative selection	12457212
7673764	7673787	17	-	28162770	OCIAML3	viability	TGGGAGAGACCGGCGCACAGAGG	TP53	ENSG00000141510	1.2276551184173243	[42]	[303]	8	hSpCas9	negative selection	12457213