Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7171
• Symbol: TPM4
• Description: tropomyosin 4

DataSource: http://genomecrispr.dkfz.de/#!/results/TPM4

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
16086519	16086542	19	+	26472758	Jiyoye	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	1.0316662464136672	[47]	[73]	6	hSpCas9	negative selection	171040
16067648	16067671	19	+	26472758	Jiyoye	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.857208302140921	[223]	[305]	6	hSpCas9	negative selection	171041
16088065	16088088	19	+	26472758	Jiyoye	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.3400585481141597	[93]	[55]	-2	hSpCas9	negative selection	171042
16081992	16082015	19	-	26472758	Jiyoye	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.6019037739487584	[172]	[197]	4	hSpCas9	negative selection	171043
16093529	16093552	19	+	26472758	Jiyoye	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	-0.44976156940229084	[258]	[142]	-3	hSpCas9	negative selection	171044
16086411	16086434	19	+	26472758	Jiyoye	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	1.3565493084359057	[28]	[55]	7	hSpCas9	negative selection	171045
16089039	16089062	19	+	26472758	Jiyoye	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	1.1888943765766282	[145]	[250]	7	hSpCas9	negative selection	171046
16088020	16088043	19	+	26472758	Jiyoye	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	3.1027819459110226	[22]	[148]	9	hSpCas9	negative selection	171047
16101256	16101279	19	+	26472758	Jiyoye	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.5915999526433007	[43]	[49]	4	hSpCas9	negative selection	171048
16086519	16086542	19	+	26472758	KBM7	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.7766589337032334	[363,286]	[103,74]	-6	hSpCas9	negative selection	362158
16067648	16067671	19	+	26472758	KBM7	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.4124714089332371	[1532,1465]	[698,1156]	4	hSpCas9	negative selection	362159
16088065	16088088	19	+	26472758	KBM7	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	0.08163722005941765	[345,288]	[113,195]	0	hSpCas9	negative selection	362160
16081992	16082015	19	-	26472758	KBM7	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.4473649041235206	[577,399]	[380,244]	5	hSpCas9	negative selection	362161
16093529	16093552	19	+	26472758	KBM7	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	-0.7226416811033589	[855,424]	[278,85]	-6	hSpCas9	negative selection	362162
16086411	16086434	19	+	26472758	KBM7	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.6348472439550409	[430,323]	[320,229]	7	hSpCas9	negative selection	362163
16089039	16089062	19	+	26472758	KBM7	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.024544931787038538	[1041,975]	[288,656]	0	hSpCas9	negative selection	362164
16088020	16088043	19	+	26472758	KBM7	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.007793675469299752	[365,498]	[129,278]	0	hSpCas9	negative selection	362165
16101256	16101279	19	+	26472758	KBM7	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.6682679234869638	[598,332]	[152,117]	-5	hSpCas9	negative selection	362166
16086519	16086542	19	+	26472758	Raji	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.18538604737487263	[143]	[37]	1	hSpCas9	negative selection	553276
16067648	16067671	19	+	26472758	Raji	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.12324994083262042	[632]	[159]	1	hSpCas9	negative selection	553277
16088065	16088088	19	+	26472758	Raji	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.018147346710259304	[95]	[21]	0	hSpCas9	negative selection	553278
16081992	16082015	19	-	26472758	Raji	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.9489541727691165	[249]	[111]	8	hSpCas9	negative selection	553279
16093529	16093552	19	+	26472758	Raji	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.6168134049273981	[280]	[99]	6	hSpCas9	negative selection	553280
16086411	16086434	19	+	26472758	Raji	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.5898489621727341	[208]	[72]	5	hSpCas9	negative selection	553281
16089039	16089062	19	+	26472758	Raji	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.16237673364850758	[515]	[106]	-1	hSpCas9	negative selection	553282
16088020	16088043	19	+	26472758	Raji	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.050352590337220504	[128]	[30]	0	hSpCas9	negative selection	553283
16101256	16101279	19	+	26472758	Raji	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.14054397806998623	[265]	[55]	-1	hSpCas9	negative selection	553284
16086519	16086542	19	+	26472758	K562	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.2871231786206853	[232]	[239]	2	hSpCas9	negative selection	744394
16067648	16067671	19	+	26472758	K562	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.07391929060400737	[1255]	[1115]	0	hSpCas9	negative selection	744395
16088065	16088088	19	+	26472758	K562	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-1.4525122046975065	[307]	[94]	-6	hSpCas9	negative selection	744396
16081992	16082015	19	-	26472758	K562	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	1.1958557622282273	[286]	[554]	8	hSpCas9	negative selection	744397
16093529	16093552	19	+	26472758	K562	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.8092033464499726	[527]	[780]	6	hSpCas9	negative selection	744398
16086411	16086434	19	+	26472758	K562	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.5948872186244587	[330]	[184]	-4	hSpCas9	negative selection	744399
16089039	16089062	19	+	26472758	K562	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.11518401651639887	[901]	[702]	-1	hSpCas9	negative selection	744400
16088020	16088043	19	+	26472758	K562	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.8739467808210475	[339]	[525]	7	hSpCas9	negative selection	744401
16101256	16101279	19	+	26472758	K562	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.016551176263847722	[307]	[262]	0	hSpCas9	negative selection	744402
16081909	16081932	19	-	26627737	DLD1	viability	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.014532094891549052	[1114]	[214,305,508]	0	hSpCas9	negative selection	803095
16101256	16101279	19	+	26627737	DLD1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.7052342877720683	[365]	[153,248,162]	7	hSpCas9	negative selection	803097
16081909	16081932	19	-	26627737	GBM cells	viability after 5 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.2701228725442666	[517]	[380,288]	4	hSpCas9	negative selection	885410
16101256	16101279	19	+	26627737	GBM cells	viability after 5 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.2747342125993439	[193]	[72,98]	-4	hSpCas9	negative selection	885412
16081909	16081932	19	-	26627737	GBM cells	viability after 13 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.15588972397446432	[517]	[434,213]	2	hSpCas9	negative selection	967725
16101256	16101279	19	+	26627737	GBM cells	viability after 13 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.2836812679588884	[193]	[115,137]	3	hSpCas9	negative selection	967727
16081909	16081932	19	-	26627737	GBM cells	viability after 21 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.01272051301066246	[517]	[285,281]	0	hSpCas9	negative selection	1050040
16101256	16101279	19	+	26627737	GBM cells	viability after 21 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.47737329171156945	[193]	[152,140]	5	hSpCas9	negative selection	1050042
16081909	16081932	19	-	26627737	RPE1	viability after 9 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	-1.4488850392828088	[4022]	[449,475]	-8	hSpCas9	negative selection	1132355
16101256	16101279	19	+	26627737	RPE1	viability after 9 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.3876524156673589	[1041]	[149,91]	-7	hSpCas9	negative selection	1132357
16081909	16081932	19	-	26627737	RPE1	viability after 12 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	-1.1020557102013577	[4022]	[622,376]	-6	hSpCas9	negative selection	1214670
16101256	16101279	19	+	26627737	RPE1	viability after 12 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.1422921742252434	[1041]	[171,78]	-7	hSpCas9	negative selection	1214672
16081909	16081932	19	-	26627737	RPE1	viability after 15 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	-1.309843031493205	[4022]	[456,460]	-7	hSpCas9	negative selection	1296985
16101256	16101279	19	+	26627737	RPE1	viability after 15 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.8363960457911839	[1041]	[216,114]	-5	hSpCas9	negative selection	1296987
16081909	16081932	19	-	26627737	RPE1	viability after 18 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	-1.2508381483798379	[4022]	[403,511]	-6	hSpCas9	negative selection	1379300
16101256	16101279	19	+	26627737	RPE1	viability after 18 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.7644327716571901	[1041]	[224,101]	-5	hSpCas9	negative selection	1379302
16081909	16081932	19	-	26627737	HeLa	viability after 8 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.9894174806112694	[823]	[882,559,728]	7	hSpCas9	negative selection	1461615
16101256	16101279	19	+	26627737	HeLa	viability after 8 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.0898558488268626	[120]	[298,49,33]	8	hSpCas9	negative selection	1461617
16081909	16081932	19	-	26627737	HeLa	viability after 12 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.9672519430509188	[823]	[608,473,932]	7	hSpCas9	negative selection	1543930
16101256	16101279	19	+	26627737	HeLa	viability after 12 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.9629054723475137	[120]	[70,112,105]	7	hSpCas9	negative selection	1543932
16081909	16081932	19	-	26627737	HeLa	viability after 15 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.8296169715372805	[823]	[630,452,712]	6	hSpCas9	negative selection	1626245
16101256	16101279	19	+	26627737	HeLa	viability after 15 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.1186819790998472	[120]	[50,146,124]	7	hSpCas9	negative selection	1626247
16081909	16081932	19	-	26627737	HeLa	viability after 18 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.8230618601653679	[823]	[414,378,712]	6	hSpCas9	negative selection	1708560
16101256	16101279	19	+	26627737	HeLa	viability after 18 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.128390242432257	[120]	[32,124,124]	7	hSpCas9	negative selection	1708562
16081909	16081932	19	-	26627737	HCT116	viability after 6 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.027328311633563418	[1620]	[425,167]	0	hSpCas9	negative selection	1790875
16101256	16101279	19	+	26627737	HCT116	viability after 6 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	2.592891354035187	[461]	[967,145]	9	hSpCas9	negative selection	1790877
16081909	16081932	19	-	26627737	HCT116	viability after 8 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.29543818275294387	[559]	[444,289,401]	3	hSpCas9	negative selection	1873190
16101256	16101279	19	+	26627737	HCT116	viability after 8 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.694388865947497	[383]	[89,75,30]	-9	hSpCas9	negative selection	1873192
16081909	16081932	19	-	26627737	HCT116	viability after 9 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.174176955958939	[1620]	[541,445]	1	hSpCas9	negative selection	1955505
16101256	16101279	19	+	26627737	HCT116	viability after 9 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.45811382826012176	[461]	[288,74]	3	hSpCas9	negative selection	1955507
16081909	16081932	19	-	26627737	HCT116	viability after 12 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.6110382550857169	[559]	[534,326,475]	6	hSpCas9	negative selection	2037820
16101256	16101279	19	+	26627737	HCT116	viability after 12 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.384118748556336	[383]	[107,66,53]	-8	hSpCas9	negative selection	2037822
16081909	16081932	19	-	26627737	HCT116	viability after 15 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.5133659441959734	[559]	[562,383,442]	5	hSpCas9	negative selection	2120135
16101256	16101279	19	+	26627737	HCT116	viability after 15 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.0085375145932418	[383]	[133,103,93]	-7	hSpCas9	negative selection	2120137
16081909	16081932	19	-	26627737	HCT116	viability after 18 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	1.052745564126751	[559]	[752,327,621]	7	hSpCas9	negative selection	2202450
16101256	16101279	19	+	26627737	HCT116	viability after 18 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.2299831413042324	[383]	[69,137,22]	-8	hSpCas9	negative selection	2202452
16067306	16067329	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTTAAAAATGGAAACAGCTAGG	TPM4	ENSG00000167460	0.6029790411592009	[965,99]	[224,122]	2	dCas9-VP64	positive selection	2402317
16067341	16067364	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTCCTTTAAGAAAATCCTAGG	TPM4	ENSG00000167460	-0.5856817180266497	[127,153]	[23,15]	-3	dCas9-VP64	positive selection	2402318
16067384	16067407	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCCAGCTCACCGTGCTCCCGG	TPM4	ENSG00000167460	-0.3803916852512492	[408,38]	[59,12]	-2	dCas9-VP64	positive selection	2402319
16099082	16099105	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGATGG	TPM4	ENSG00000167460	2.740144461675261	[44,53]	[104,38]	8	dCas9-VP64	positive selection	2402732
16090343	16090366	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCAGG	TPM4	ENSG00000167460	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451807
16080764	16080787	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCATTGCACTCCAGCCTTGG	TPM4	ENSG00000167460	2.033062228314259	[28,209]	[4,221]	7	dCas9-VP64	positive selection	2456520
16087237	16087260	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCCACTGCACTCCAGCCTTGG	TPM4	ENSG00000167460	0.6631647882125523	[138,30]	[44,11]	3	dCas9-VP64	positive selection	2473816
16067306	16067329	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTTAAAAATGGAAACAGCTAGG	TPM4	ENSG00000167460	-0.8127016586296064	[102,56]	[19,8]	-7	dCas9-VP64	positive selection	2497572
16067341	16067364	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTCCTTTAAGAAAATCCTAGG	TPM4	ENSG00000167460	0.6850275053831393	[111,219]	[57,113]	5	dCas9-VP64	positive selection	2497573
16067384	16067407	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCCAGCTCACCGTGCTCCCGG	TPM4	ENSG00000167460	-0.742910885369887	[39,225]	[13,35]	-7	dCas9-VP64	positive selection	2497574
16099082	16099105	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGATGG	TPM4	ENSG00000167460	-0.0021690128549880505	[109,77]	[41,19]	0	dCas9-VP64	positive selection	2497987
16090343	16090366	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCAGG	TPM4	ENSG00000167460	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547062
16080764	16080787	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCATTGCACTCCAGCCTTGG	TPM4	ENSG00000167460	0.2042793589460996	[254,297]	[44,158]	1	dCas9-VP64	positive selection	2551775
16087237	16087260	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCCACTGCACTCCAGCCTTGG	TPM4	ENSG00000167460	-0.07877572482445189	[107,69]	[28,25]	0	dCas9-VP64	positive selection	2569071
16081939	16081962	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.8226068485611983	[1,2]	[0,0]	-8	hSpCas9	positive selection	3028774
16081955	16081978	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	-0.12030870574929861	[2,3]	[4,0]	-2	hSpCas9	positive selection	3028775
16081939	16081962	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.4733387692225042	[1,1]	[0,0]	-6	hSpCas9	positive selection	3096632
16081955	16081978	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	0.8801797826676615	[2,2]	[3,4]	9	hSpCas9	positive selection	3096633
16101256	16101279		+	24336571	A375	resistance to PLX after 7 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.130370656301886	[9,17]	[10,13]	-4	hSpCas9	positive selection	3152251
16081906	16081929		+	24336571	A375	resistance to PLX after 7 days	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.008062569303807193	[9,13]	[10,12]	0	hSpCas9	positive selection	3152253
16101256	16101279		+	24336571	A375	resistance to PLX after 14 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.46181040805376916	[11,14]	[4,2]	-5	hSpCas9	positive selection	3210044
16081906	16081929		+	24336571	A375	resistance to PLX after 14 days	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.6678922618998162	[7,8]	[5,4]	6	hSpCas9	positive selection	3210046
16101256	16101279		+	24336571	A375	viability after 7 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.0535466467228491	[13]	[9,17]	0	hSpCas9	negative selection	3267837
16081906	16081929		+	24336571	A375	viability after 7 days	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.5520720021567128	[7]	[9,13]	8	hSpCas9	negative selection	3267839
16101256	16101279		+	24336571	A375	viability after 14 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.0031224360692220926	[13]	[11,14]	0	hSpCas9	negative selection	3325630
16081906	16081929		+	24336571	A375	viability after 14 days	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.060465112517926856	[7]	[7,8]	0	hSpCas9	negative selection	3325632
16081906	16081929	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.10899600279998067	[164,164]	[0,0]	0	hSpCas9	positive selection	3398698
16081939	16081962	19	-	26780180	HT29	viability (Avana library 4 designs)	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	2.48190358726533	[]	[]	8	hSpCas9	negative selection	3467610
16081954	16081977	19	+	26780180	HT29	viability (Avana library 4 designs)	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	1.95370665204368	[]	[]	7	hSpCas9	negative selection	3467611
16081939	16081962	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-3.72748039039723	[]	[]	-4	hSpCas9	negative selection	3571870
16081954	16081977	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	-2.09006435438636	[]	[]	-3	hSpCas9	negative selection	3571871
16081975	16081998	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	5.33482775348188	[]	[]	8	hSpCas9	negative selection	3571872
16081939	16081962	19	-	26780180	A375	viability (Avana lentiGuide)	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	23.2233708133765	[]	[]	9	hSpCas9	negative selection	3680529
16081954	16081977	19	+	26780180	A375	viability (Avana lentiGuide)	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	7.86073989452534	[]	[]	6	hSpCas9	negative selection	3680530
16081975	16081998	19	+	26780180	A375	viability (Avana lentiGuide)	GGCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	4.04978894130138	[]	[]	4	hSpCas9	negative selection	3680531
16081939	16081962	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-1.7431374449448012	[4]	[1,0]	-9	hSpCas9	positive selection	3789136
16081954	16081977	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	-0.19055858952236185	[4]	[3,3]	-3	hSpCas9	positive selection	3789137
16081975	16081998	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.3152574617561804	[4]	[5,5]	8	hSpCas9	positive selection	3789138
16081939	16081962	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-1.7263714470914617	[4]	[0,0]	-9	hSpCas9	positive selection	3897743
16081954	16081977	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTTGAGGAGGAGTTGGACAGGG	TPM4	ENSG00000167460	-0.7637421934989036	[5]	[1,2]	-7	hSpCas9	positive selection	3897744
16081975	16081998	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.20234150769766202	[5]	[4,4]	5	hSpCas9	positive selection	3897745
16101256	16101279	19	+	26780180	A375	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.44683980533257	[]	[]	8	hSpCas9	negative selection	4007065
16081906	16081929	19	+	26780180	A375	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	1.30983990530254	[]	[]	7	hSpCas9	negative selection	4007066
16101256	16101279	19	+	26780180	HT29	viability (GeCKOv2 library)	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.18830433168848	[]	[]	6	hSpCas9	negative selection	4115031
16081906	16081929	19	+	26780180	HT29	viability (GeCKOv2 library)	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.874153705276422	[]	[]	3	hSpCas9	negative selection	4115032
16101256	16101279	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.28828573367546323	[3]	[1,1]	-6	hSpCas9	positive selection	4178791
16081906	16081929	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.037116574084657676	[3]	[1,2]	-1	hSpCas9	positive selection	4178794
16101256	16101279	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.9663540411041909	[2]	[5,3,4,0]	6	hSpCas9	positive selection	4242813
16081906	16081929	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	1.0409797648590082	[1]	[1,2,4,0]	7	hSpCas9	positive selection	4242816
16101256	16101279	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.20194537498581225	[2]	[3,0]	-4	hSpCas9	positive selection	4304773
16093728	16093751	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.7674267497060779	[1]	[0,0]	-9	hSpCas9	positive selection	4369018
16081906	16081929	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.17797900182523982	[3]	[2,2]	3	hSpCas9	positive selection	4369022
16081939	16081961	19	-	27760321	OCIAML3	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-1.3605830386714262	[631,562]	[136,239]	-8	hSpCas9	negative selection	4449501
16081976	16081998	19	+	27760321	OCIAML3	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.3643494700209215	[461,321]	[331,465]	4	hSpCas9	negative selection	4449502
16086412	16086434	19	+	27760321	OCIAML3	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.04611102537526811	[417,373]	[324,311]	0	hSpCas9	negative selection	4449503
16086517	16086539	19	+	27760321	OCIAML3	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.6902839748005695	[334,272]	[349,422]	7	hSpCas9	negative selection	4449504
16089040	16089062	19	+	27760321	OCIAML3	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.006179008742978463	[524,393]	[323,394]	0	hSpCas9	negative selection	4449505
16081939	16081961	19	-	27760321	OCIAML2	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.5896590913120598	[631,562]	[277,376]	-6	hSpCas9	negative selection	4532964
16081976	16081998	19	+	27760321	OCIAML2	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.8658130023726749	[461,321]	[544,605]	9	hSpCas9	negative selection	4532965
16086412	16086434	19	+	27760321	OCIAML2	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.5967213913439744	[417,373]	[340,671]	7	hSpCas9	negative selection	4532966
16086517	16086539	19	+	27760321	OCIAML2	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.42438688304024696	[334,272]	[276,395]	6	hSpCas9	negative selection	4532967
16089040	16089062	19	+	27760321	OCIAML2	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.1465112335418863	[524,393]	[291,386]	-2	hSpCas9	negative selection	4532968
16081939	16081961	19	-	27760321	MV411	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.8084248771839123	[631,562]	[0,560]	-5	hSpCas9	negative selection	4616427
16081976	16081998	19	+	27760321	MV411	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.8565940575114628	[461,321]	[319,677]	6	hSpCas9	negative selection	4616428
16086412	16086434	19	+	27760321	MV411	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-1.0102606631945719	[417,373]	[91,185]	-6	hSpCas9	negative selection	4616429
16086517	16086539	19	+	27760321	MV411	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.2947889316410495	[334,272]	[289,176]	2	hSpCas9	negative selection	4616430
16089040	16089062	19	+	27760321	MV411	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.6259448357499311	[524,393]	[235,132]	-4	hSpCas9	negative selection	4616431
16081939	16081961	19	-	27760321	HL60	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.7511837907485198	[631,562]	[307,269]	-7	hSpCas9	negative selection	4699890
16081976	16081998	19	+	27760321	HL60	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.119858310517806	[461,321]	[604,775]	9	hSpCas9	negative selection	4699891
16086412	16086434	19	+	27760321	HL60	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	1.1780137113974973	[417,373]	[531,941]	9	hSpCas9	negative selection	4699892
16086517	16086539	19	+	27760321	HL60	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.2796141146720752	[334,272]	[213,390]	3	hSpCas9	negative selection	4699893
16089040	16089062	19	+	27760321	HL60	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.12461497402365765	[524,393]	[447,360]	1	hSpCas9	negative selection	4699894
16081939	16081961	19	-	27760321	HT1080	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	0.1281469310908328	[562,439]	[109,336]	0	hSpCas9	negative selection	4783353
16081976	16081998	19	+	27760321	HT1080	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	2.2537652718097263	[321,250]	[855,202]	9	hSpCas9	negative selection	4783354
16086412	16086434	19	+	27760321	HT1080	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.10472262570926588	[373,291]	[71,219]	0	hSpCas9	negative selection	4783355
16086517	16086539	19	+	27760321	HT1080	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	-0.5481626845312312	[272,212]	[80,49]	-2	hSpCas9	negative selection	4783356
16089040	16089062	19	+	27760321	HT1080	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.08979241994476467	[393,307]	[123,175]	0	hSpCas9	negative selection	4783357
16081939	16081961	19	-	27760321	HT29	viability after 7 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	0.04383079516022964	[562,439]	[819,518,675]	0	hSpCas9	negative selection	4866816
16081976	16081998	19	+	27760321	HT29	viability after 7 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.3136574848996971	[321,250]	[1142,789,846]	9	hSpCas9	negative selection	4866817
16086412	16086434	19	+	27760321	HT29	viability after 7 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.15013155580363324	[373,291]	[417,435,309]	-2	hSpCas9	negative selection	4866818
16086517	16086539	19	+	27760321	HT29	viability after 7 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	-0.16046763281792187	[272,212]	[383,122,343]	-2	hSpCas9	negative selection	4866819
16089040	16089062	19	+	27760321	HT29	viability after 7 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.386219315356396	[393,307]	[545,546,666]	6	hSpCas9	negative selection	4866820
16081939	16081961	19	-	27760321	HT29	viability after 25 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.6968477609824221	[562,439]	[355,273,438]	-5	hSpCas9	negative selection	4950279
16081976	16081998	19	+	27760321	HT29	viability after 25 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.2647402012332156	[321,250]	[809,737,811]	9	hSpCas9	negative selection	4950280
16086412	16086434	19	+	27760321	HT29	viability after 25 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.053865086190247685	[373,291]	[314,294,600]	0	hSpCas9	negative selection	4950281
16086517	16086539	19	+	27760321	HT29	viability after 25 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.3525140898143412	[272,212]	[255,392,427]	4	hSpCas9	negative selection	4950282
16089040	16089062	19	+	27760321	HT29	viability after 25 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.7905688869789529	[393,307]	[566,678,859]	8	hSpCas9	negative selection	4950283
16081939	16081961	19	-	27760321	HT29	viability after 22 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.6961386660806793	[562,439]	[474,177,417]	-5	hSpCas9	negative selection	5033742
16081976	16081998	19	+	27760321	HT29	viability after 22 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.044808153757268	[321,250]	[819,757,465]	9	hSpCas9	negative selection	5033743
16086412	16086434	19	+	27760321	HT29	viability after 22 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.18731103976235208	[373,291]	[419,301,594]	2	hSpCas9	negative selection	5033744
16086517	16086539	19	+	27760321	HT29	viability after 22 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.1455726588233246	[272,212]	[309,334,286]	1	hSpCas9	negative selection	5033745
16089040	16089062	19	+	27760321	HT29	viability after 22 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.7463972646277282	[393,307]	[854,359,823]	8	hSpCas9	negative selection	5033746
16081939	16081961	19	-	27760321	HT29	viability after 19 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.32836727114037645	[562,439]	[437,225,694]	-3	hSpCas9	negative selection	5117205
16081976	16081998	19	+	27760321	HT29	viability after 19 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.6743282775586792	[321,250]	[792,400,406]	7	hSpCas9	negative selection	5117206
16086412	16086434	19	+	27760321	HT29	viability after 19 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.014411419067933987	[373,291]	[180,527,421]	0	hSpCas9	negative selection	5117207
16086517	16086539	19	+	27760321	HT29	viability after 19 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	-0.04088840622546264	[272,212]	[249,337,221]	0	hSpCas9	negative selection	5117208
16089040	16089062	19	+	27760321	HT29	viability after 19 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	1.12532499988352	[393,307]	[755,1054,805]	9	hSpCas9	negative selection	5117209
16081939	16081961	19	-	27760321	HT29	viability after 16 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-0.700210761718014	[562,439]	[422,282,338]	-6	hSpCas9	negative selection	5200668
16081976	16081998	19	+	27760321	HT29	viability after 16 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.4003089483909843	[321,250]	[862,827,848]	9	hSpCas9	negative selection	5200669
16086412	16086434	19	+	27760321	HT29	viability after 16 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.3818320895288489	[373,291]	[402,657,382]	4	hSpCas9	negative selection	5200670
16086517	16086539	19	+	27760321	HT29	viability after 16 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.10762093664787664	[272,212]	[158,256,450]	1	hSpCas9	negative selection	5200671
16089040	16089062	19	+	27760321	HT29	viability after 16 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.26390171333404866	[393,307]	[419,385,605]	3	hSpCas9	negative selection	5200672
16081939	16081961	19	-	27760321	HT29	viability after 13 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-1.3415450226682326	[562,439]	[139,217,324]	-8	hSpCas9	negative selection	5284131
16081976	16081998	19	+	27760321	HT29	viability after 13 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	0.8781912720768075	[321,250]	[584,592,651]	9	hSpCas9	negative selection	5284132
16086412	16086434	19	+	27760321	HT29	viability after 13 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.13619042547511573	[373,291]	[467,315,274]	-2	hSpCas9	negative selection	5284133
16086517	16086539	19	+	27760321	HT29	viability after 13 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.053841809144230535	[272,212]	[359,196,318]	0	hSpCas9	negative selection	5284134
16089040	16089062	19	+	27760321	HT29	viability after 13 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.41897194914013147	[393,307]	[580,435,611]	5	hSpCas9	negative selection	5284135
16081939	16081961	19	-	27760321	HT29	viability after 10 days	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-1.4126000729301678	[562,439]	[267,247,190]	-8	hSpCas9	negative selection	5367594
16081976	16081998	19	+	27760321	HT29	viability after 10 days	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.006412043778235	[321,250]	[634,724,793]	9	hSpCas9	negative selection	5367595
16086412	16086434	19	+	27760321	HT29	viability after 10 days	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.041483805332204624	[373,291]	[407,423,380]	0	hSpCas9	negative selection	5367596
16086517	16086539	19	+	27760321	HT29	viability after 10 days	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	0.29368814821591577	[272,212]	[415,359,339]	4	hSpCas9	negative selection	5367597
16089040	16089062	19	+	27760321	HT29	viability after 10 days	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.5078262764057806	[393,307]	[519,538,803]	7	hSpCas9	negative selection	5367598
16081939	16081961	19	-	27760321	MOLM13	viability	CTCAACGAGCTGGATGCGTCGG	TPM4	ENSG00000167460	-4.3362379560222175	[631,562]	[0,29]	-9	hSpCas9	negative selection	5451057
16081976	16081998	19	+	27760321	MOLM13	viability	GCTCAGGAACGACTGGCCACGG	TPM4	ENSG00000167460	1.8016136334974218	[461,321]	[1128,449]	9	hSpCas9	negative selection	5451058
16086412	16086434	19	+	27760321	MOLM13	viability	GCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.5056645041135128	[417,373]	[305,325]	3	hSpCas9	negative selection	5451059
16086517	16086539	19	+	27760321	MOLM13	viability	GAGGCTGACCGCAAATACGAGG	TPM4	ENSG00000167460	-0.2665369624733297	[334,272]	[284,19]	-2	hSpCas9	negative selection	5451060
16089040	16089062	19	+	27760321	MOLM13	viability	TGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.6751999596065246	[524,393]	[140,177]	-4	hSpCas9	negative selection	5451061
16067824	16067847	19	+	27661255	K562	viability	GCAGACACCTGCGGGAGGATAGG	TPM4	ENSG00000167460	0.14184883827348327	[495,643]	[526,476]	5	dCas9-KRAB	negative selection	5519307
16067827	16067850	19	+	27661255	K562	viability	GACACCTGCGGGAGGATAGGAGG	TPM4	ENSG00000167460	0.14236847810124864	[734,843]	[689,697]	5	dCas9-KRAB	negative selection	5519308
16067909	16067932	19	+	27661255	K562	viability	GCTGGAAGAGGGGTGACGATCGG	TPM4	ENSG00000167460	-0.19858969969610984	[252,164]	[158,135]	-6	dCas9-KRAB	negative selection	5519309
16067575	16067598	19	-	27661255	K562	viability	GGTGCGCGGCGGGCTCTGTGGGG	TPM4	ENSG00000167460	0.3259635356842477	[560,676]	[641,596]	9	dCas9-KRAB	negative selection	5519310
16067597	16067620	19	-	27661255	K562	viability	GGCGCTGGCGTGGGGGACGTGGG	TPM4	ENSG00000167460	0.0002194019500476735	[839,767]	[624,658]	0	dCas9-KRAB	negative selection	5519311
16067747	16067770	19	-	27661255	K562	viability	GCCCGGAGCGGCCCAGCGGAGGG	TPM4	ENSG00000167460	0.02093385088877331	[392,560]	[361,402]	0	dCas9-KRAB	negative selection	5519312
16067810	16067833	19	-	27661255	K562	viability	GGTGTCTGCGACCCCCAACTGGG	TPM4	ENSG00000167460	0.3726085965339654	[72,160]	[127,111]	9	dCas9-KRAB	negative selection	5519313
16101256	16101279	19	+	27260156	BXPC3	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.24126204667459009	[409]	[505,477,464,584]	5	hSpCas9	negative selection	5577233
16093728	16093751	19	+	27260156	BXPC3	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.2587269242390005	[140]	[42,62,74,67]	-9	hSpCas9	negative selection	5641478
16081906	16081929	19	+	27260156	BXPC3	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.25142369878176807	[482]	[307,381,559,466]	-5	hSpCas9	negative selection	5641482
16101256	16101279	19	+	27260156	A673	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.4675241997192541	[409]	[746,617,666,699]	9	hSpCas9	negative selection	5698484
16093728	16093751	19	+	27260156	A673	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.1371087064793508	[140]	[86,37,87,97]	-9	hSpCas9	negative selection	5762729
16081906	16081929	19	+	27260156	A673	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.011171445840481527	[482]	[643,496,572,597]	0	hSpCas9	negative selection	5762733
16101256	16101279	19	+	27260156	A375	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.3211588054443303	[409]	[469,633,638,645]	5	hSpCas9	negative selection	5819735
16093728	16093751	19	+	27260156	A375	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.2181553327171306	[140]	[58,51,25,9]	-9	hSpCas9	negative selection	5883980
16081906	16081929	19	+	27260156	A375	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.5980847081776688	[482]	[206,463,375,444]	-7	hSpCas9	negative selection	5883984
16101256	16101279	19	+	27260156	COLO741	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.1711299735411091	[409]	[626,731,424]	3	hSpCas9	negative selection	5940986
16093728	16093751	19	+	27260156	COLO741	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.6656797593469339	[140]	[61,157,115]	-8	hSpCas9	negative selection	6005231
16081906	16081929	19	+	27260156	COLO741	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.21409171375850986	[482]	[594,457,545]	-4	hSpCas9	negative selection	6005235
16101256	16101279	19	+	27260156	CAL120	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.6798612974156143	[409]	[1108,650,736]	8	hSpCas9	negative selection	6062237
16093728	16093751	19	+	27260156	CAL120	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.2127994058449456	[140]	[54,16,43]	-9	hSpCas9	negative selection	6126482
16081906	16081929	19	+	27260156	CAL120	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.1949572296086236	[482]	[703,489,409]	-3	hSpCas9	negative selection	6126486
16101256	16101279	19	+	27260156	CADOES1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.11083886689255901	[409]	[358,368,484,434]	2	hSpCas9	negative selection	6183488
16093728	16093751	19	+	27260156	CADOES1	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.1912857191569264	[140]	[74,11,73,68]	-9	hSpCas9	negative selection	6247733
16081906	16081929	19	+	27260156	CADOES1	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.19134537308736996	[482]	[414,365,489,298]	-3	hSpCas9	negative selection	6247737
16101256	16101279	19	+	27260156	EWS502	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.026321163495692107	[409]	[545,407,341,459]	0	hSpCas9	negative selection	6304739
16093728	16093751	19	+	27260156	EWS502	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.5015390653689382	[140]	[11,34,90,80]	-9	hSpCas9	negative selection	6368984
16081906	16081929	19	+	27260156	EWS502	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.056268815250888976	[482]	[383,606,371,618]	-1	hSpCas9	negative selection	6368988
16101256	16101279	19	+	27260156	EW8	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.13334997494262454	[409]	[467,279,260,475]	2	hSpCas9	negative selection	6425990
16093728	16093751	19	+	27260156	EW8	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.1657291494901525	[140]	[37,9,31,21]	-9	hSpCas9	negative selection	6490235
16081906	16081929	19	+	27260156	EW8	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.27866767076671783	[482]	[376,299,314,304]	-5	hSpCas9	negative selection	6490239
16101256	16101279	19	+	27260156	CORL105	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.08608913012020519	[409]	[374,432,641,604]	1	hSpCas9	negative selection	6547241
16093728	16093751	19	+	27260156	CORL105	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.8452332189784475	[140]	[32,158,71,96]	-9	hSpCas9	negative selection	6611486
16081906	16081929	19	+	27260156	CORL105	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.3927547581467978	[482]	[357,413,542,422]	-6	hSpCas9	negative selection	6611490
16101256	16101279	19	+	27260156	HS294T	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.02159184790360319	[409]	[133,158,155,203]	0	hSpCas9	negative selection	6668492
16093728	16093751	19	+	27260156	HS294T	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.4358997643080054	[140]	[6,1,15,16]	-9	hSpCas9	negative selection	6732737
16081906	16081929	19	+	27260156	HS294T	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.09034810684446384	[482]	[128,185,170,227]	-1	hSpCas9	negative selection	6732741
16101256	16101279	19	+	27260156	HCC44	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.25730898186454537	[409]	[723,374,794,405]	4	hSpCas9	negative selection	6789743
16093728	16093751	19	+	27260156	HCC44	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.314556695257531	[140]	[37,13,13,60]	-9	hSpCas9	negative selection	6853988
16081906	16081929	19	+	27260156	HCC44	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.14283549128766265	[482]	[605,215,654,572]	-2	hSpCas9	negative selection	6853992
16101256	16101279	19	+	27260156	G402	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.9305610557945013	[409]	[1119,716,1352,645]	9	hSpCas9	negative selection	6910994
16093728	16093751	19	+	27260156	G402	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-3.1417247973177425	[140]	[10,14,0,47]	-9	hSpCas9	negative selection	6975239
16081906	16081929	19	+	27260156	G402	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.2270165010252969	[482]	[392,774,381,463]	-3	hSpCas9	negative selection	6975243
16101256	16101279	19	+	27260156	L33	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.02398675839015607	[409]	[344,159,225,517]	0	hSpCas9	negative selection	7032245
16093728	16093751	19	+	27260156	L33	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.7172542640510444	[140]	[87,39,47,80]	-9	hSpCas9	negative selection	7096490
16081906	16081929	19	+	27260156	L33	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.1143683423456554	[482]	[551,150,306,373]	-3	hSpCas9	negative selection	7096494
16101256	16101279	19	+	27260156	K562	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.3686317603770096	[409]	[228,521,892,242]	4	hSpCas9	negative selection	7153496
16093728	16093751	19	+	27260156	K562	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-3.231942522586495	[140]	[8,11,10,19]	-9	hSpCas9	negative selection	7217741
16081906	16081929	19	+	27260156	K562	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.6566685052108245	[482]	[319,212,260,290]	-6	hSpCas9	negative selection	7217745
16101256	16101279	19	+	27260156	HT29	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.236112047991525	[409]	[737,601,575,456]	4	hSpCas9	negative selection	7274747
16093728	16093751	19	+	27260156	HT29	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.367852641434254	[140]	[106,57,66,38]	-9	hSpCas9	negative selection	7338992
16081906	16081929	19	+	27260156	HT29	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.046541016453081535	[482]	[555,649,500,701]	0	hSpCas9	negative selection	7338996
16101256	16101279	19	+	27260156	MHHES1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.054512441122323174	[409]	[532,492,573,346]	1	hSpCas9	negative selection	7395998
16093728	16093751	19	+	27260156	MHHES1	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.0769093602373194	[140]	[78,60,75,80]	-9	hSpCas9	negative selection	7460243
16081906	16081929	19	+	27260156	MHHES1	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.16425439249229962	[482]	[540,522,631,291]	-3	hSpCas9	negative selection	7460247
16101256	16101279	19	+	27260156	MEWO	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.23707436700699497	[409]	[525,345,498]	5	hSpCas9	negative selection	7517249
16093728	16093751	19	+	27260156	MEWO	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.7431797029996072	[140]	[173,47,32]	-9	hSpCas9	negative selection	7581494
16081906	16081929	19	+	27260156	MEWO	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.00015000061214669874	[482]	[497,519,345]	0	hSpCas9	negative selection	7581498
16101256	16101279	19	+	27260156	LNCAPCLONEFGC	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.4401399891495965	[409]	[582,308,654,501]	7	hSpCas9	negative selection	7638500
16093728	16093751	19	+	27260156	LNCAPCLONEFGC	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.405196931384305	[140]	[26,23,34,11]	-9	hSpCas9	negative selection	7702745
16081906	16081929	19	+	27260156	LNCAPCLONEFGC	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.6284462795480117	[482]	[264,201,352,327]	-7	hSpCas9	negative selection	7702749
16101256	16101279	19	+	27260156	PANC0327	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.2060909630231755	[409]	[416,309,356,187]	-3	hSpCas9	negative selection	7759751
16093728	16093751	19	+	27260156	PANC0327	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.8482468313650633	[140]	[38,152,54,17]	-8	hSpCas9	negative selection	7823996
16081906	16081929	19	+	27260156	PANC0327	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.02329510406183504	[482]	[423,517,232,500]	0	hSpCas9	negative selection	7824000
16101256	16101279	19	+	27260156	NCIH2009	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.11467781654739288	[409]	[721,550,607]	1	hSpCas9	negative selection	7881002
16093728	16093751	19	+	27260156	NCIH2009	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.3508300567524847	[140]	[47,18,50]	-9	hSpCas9	negative selection	7945247
16081906	16081929	19	+	27260156	NCIH2009	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.1298669899387804	[482]	[822,777,285]	-2	hSpCas9	negative selection	7945251
16101256	16101279	19	+	27260156	NCIH1373	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.6014888310721247	[409]	[631,726,736,176]	6	hSpCas9	negative selection	8002253
16093728	16093751	19	+	27260156	NCIH1373	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.877407594692216	[140]	[3,57,8,1]	-9	hSpCas9	negative selection	8066498
16081906	16081929	19	+	27260156	NCIH1373	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-1.0923398242844866	[482]	[392,126,221,81]	-8	hSpCas9	negative selection	8066502
16101256	16101279	19	+	27260156	PATU8902	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.1944916204661313	[409]	[872,231,885,538]	2	hSpCas9	negative selection	8123504
16093728	16093751	19	+	27260156	PATU8902	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-4.576653435646997	[140]	[2,28,0,0]	-9	hSpCas9	negative selection	8187749
16081906	16081929	19	+	27260156	PATU8902	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-1.247154134210379	[482]	[211,69,273,617]	-8	hSpCas9	negative selection	8187753
16101256	16101279	19	+	27260156	PANC1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.4478112090530947	[409]	[608,561,429,347]	7	hSpCas9	negative selection	8244755
16093728	16093751	19	+	27260156	PANC1	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.729702138425137	[140]	[73,9,24,30]	-9	hSpCas9	negative selection	8309000
16081906	16081929	19	+	27260156	PANC1	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.11408501015646873	[482]	[512,405,262,350]	-2	hSpCas9	negative selection	8309004
16101256	16101279	19	+	27260156	PANC0813	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.3446301832019907	[409]	[511,573,796,556]	5	hSpCas9	negative selection	8366006
16093728	16093751	19	+	27260156	PANC0813	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.740130918864783	[140]	[21,22,13,38]	-9	hSpCas9	negative selection	8430251
16081906	16081929	19	+	27260156	PANC0813	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	0.014465986916083598	[482]	[378,913,382,594]	0	hSpCas9	negative selection	8430255
16101256	16101279	19	+	27260156	RDES	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.34266568070600867	[409]	[447,596,704,671]	5	hSpCas9	negative selection	8487257
16093728	16093751	19	+	27260156	RDES	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.193144172365897	[140]	[28,18,59,36]	-9	hSpCas9	negative selection	8551502
16081906	16081929	19	+	27260156	RDES	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.25113174429716817	[482]	[313,525,541,507]	-4	hSpCas9	negative selection	8551506
16101256	16101279	19	+	27260156	PC3	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.20142382748048565	[409]	[359,476,656,449]	4	hSpCas9	negative selection	8608508
16093728	16093751	19	+	27260156	PC3	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.7800989771807669	[140]	[56,65,33,157]	-9	hSpCas9	negative selection	8672753
16081906	16081929	19	+	27260156	PC3	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.23920985967074856	[482]	[267,424,635,409]	-5	hSpCas9	negative selection	8672757
16101256	16101279	19	+	27260156	PATU8988T	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.6400859221061487	[409]	[423,790,782,473]	9	hSpCas9	negative selection	8729759
16093728	16093751	19	+	27260156	PATU8988T	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.97556107612151	[140]	[23,41,20,53]	-9	hSpCas9	negative selection	8794004
16081906	16081929	19	+	27260156	PATU8988T	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.018541543065970133	[482]	[428,419,422,576]	0	hSpCas9	negative selection	8794008
16101256	16101279	19	+	27260156	T47D	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.3410360143638611	[409]	[560,567,658,634]	7	hSpCas9	negative selection	8851010
16093728	16093751	19	+	27260156	T47D	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.3228932962101358	[140]	[95,62,46,56]	-9	hSpCas9	negative selection	8915255
16081906	16081929	19	+	27260156	T47D	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.20073702075620087	[482]	[600,447,451,460]	-4	hSpCas9	negative selection	8915259
16101256	16101279	19	+	27260156	SU8686	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.35577733357044855	[409]	[430,451,621,607]	6	hSpCas9	negative selection	8972261
16093728	16093751	19	+	27260156	SU8686	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-2.526235720733295	[140]	[25,18,24,27]	-9	hSpCas9	negative selection	9036506
16081906	16081929	19	+	27260156	SU8686	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.40208912986295	[482]	[298,308,361,515]	-6	hSpCas9	negative selection	9036510
16101256	16101279	19	+	27260156	SKES1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.27214246926157903	[409]	[584,473,631,309]	6	hSpCas9	negative selection	9093512
16093728	16093751	19	+	27260156	SKES1	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.5570563040855891	[140]	[30,60,50,46]	-9	hSpCas9	negative selection	9157757
16081906	16081929	19	+	27260156	SKES1	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.3465842151170346	[482]	[464,531,357,207]	-6	hSpCas9	negative selection	9157761
16101256	16101279	19	+	27260156	TOV112D	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.5473618783522779	[409]	[539,856,438,620]	8	hSpCas9	negative selection	9214763
16093728	16093751	19	+	27260156	TOV112D	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.5222236054691105	[140]	[51,72,39,37]	-9	hSpCas9	negative selection	9279008
16081906	16081929	19	+	27260156	TOV112D	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.14878731965730235	[482]	[442,592,500,251]	-3	hSpCas9	negative selection	9279012
16101256	16101279	19	+	27260156	TC71	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.1741986314952242	[409]	[418,488,444,642]	4	hSpCas9	negative selection	9336014
16093728	16093751	19	+	27260156	TC71	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-0.782327110956458	[140]	[104,108,53,83]	-9	hSpCas9	negative selection	9400259
16081906	16081929	19	+	27260156	TC71	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.1176807629208476	[482]	[613,443,443,399]	-3	hSpCas9	negative selection	9400263
16101256	16101279	19	+	27260156	TC32	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.2484215123540129	[409]	[435,408,645,358]	4	hSpCas9	negative selection	9457265
16093728	16093751	19	+	27260156	TC32	viability	GGAAAAGACAATTGATGACCTGG	TPM4	ENSG00000167460	-1.238313787108085	[140]	[33,57,60,71]	-9	hSpCas9	negative selection	9521510
16081906	16081929	19	+	27260156	TC32	viability	TCCCCAGGCTGAAGGTGATGTGG	TPM4	ENSG00000167460	-0.2506078072201087	[482]	[495,130,443,533]	-4	hSpCas9	negative selection	9521514
16081909	16081932	19	-	27869803	HPAFII	viability after 27 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.559867988363435	[437]	[369,313,NaN]	4	hSpCas9	negative selection	9566131
16101256	16101279	19	+	27869803	HPAFII	viability after 27 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.6122698467168916	[248]	[71,96,NaN]	-4	hSpCas9	negative selection	9566133
16081909	16081932	19	-	27869803	HPAFII	viability after 15 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.15970690899584306	[437]	[724,401,NaN]	1	hSpCas9	negative selection	9648580
16101256	16101279	19	+	27869803	HPAFII	viability after 15 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.01933865496442846	[248]	[121,363,NaN]	0	hSpCas9	negative selection	9648582
16081909	16081932	19	-	27869803	ASPC1	viability after 36 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	-0.5882910781652858	[1318]	[387,262,279]	-5	hSpCas9	negative selection	9731029
16101256	16101279	19	+	27869803	ASPC1	viability after 36 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.125432427681378	[626]	[235,44,47]	-8	hSpCas9	negative selection	9731031
16081909	16081932	19	-	27869803	PATU8988S	viability after 35 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.598660571187731	[1069]	[687,616,NaN]	6	hSpCas9	negative selection	9813478
16101256	16101279	19	+	27869803	PATU8988S	viability after 35 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.28303711251788777	[480]	[109,361,NaN]	3	hSpCas9	negative selection	9813480
16081909	16081932	19	-	27869803	PATU8988S	viability after 31 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.5218010380850612	[1069]	[656,555,NaN]	6	hSpCas9	negative selection	9895927
16101256	16101279	19	+	27869803	PATU8988S	viability after 31 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.02283032575024785	[480]	[72,349,NaN]	0	hSpCas9	negative selection	9895929
16081909	16081932	19	-	27869803	HPAFII	viability after 35 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.43790581533378203	[437]	[218,391,NaN]	3	hSpCas9	negative selection	9978376
16101256	16101279	19	+	27869803	HPAFII	viability after 35 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.13202669730123573	[248]	[59,176,NaN]	-1	hSpCas9	negative selection	9978378
16081909	16081932	19	-	27869803	HPAFII	viability after 31 days	CGGCCACATCACCTTCAGCCTGG	TPM4	ENSG00000167460	0.39486752793851676	[437]	[282,366,NaN]	3	hSpCas9	negative selection	10060825
16101256	16101279	19	+	27869803	HPAFII	viability after 31 days	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.29835821547588764	[248]	[71,158,NaN]	-2	hSpCas9	negative selection	10060827
16086519	16086542	19	+	28162770	P31FUJ	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.4500329206350475	[92]	[79]	-4	hSpCas9	negative selection	10255767
16067648	16067671	19	+	28162770	P31FUJ	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.01836659334224855	[935]	[1113]	0	hSpCas9	negative selection	10255768
16088065	16088088	19	+	28162770	P31FUJ	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.419887757014874	[73]	[64]	-4	hSpCas9	negative selection	10255769
16081992	16082015	19	-	28162770	P31FUJ	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.9705259552951476	[184]	[425]	9	hSpCas9	negative selection	10255770
16093529	16093552	19	+	28162770	P31FUJ	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.9570223544656384	[191]	[437]	9	hSpCas9	negative selection	10255771
16086411	16086434	19	+	28162770	P31FUJ	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.33518721770306414	[113]	[168]	3	hSpCas9	negative selection	10255772
16089039	16089062	19	+	28162770	P31FUJ	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.23523227239718003	[607]	[840]	2	hSpCas9	negative selection	10255773
16088020	16088043	19	+	28162770	P31FUJ	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.2783962416347231	[213]	[304]	3	hSpCas9	negative selection	10255774
16101256	16101279	19	+	28162770	P31FUJ	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.1186311844950676	[254]	[137]	-7	hSpCas9	negative selection	10255775
16086519	16086542	19	+	28162770	TF1	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10425133
16067648	16067671	19	+	28162770	TF1	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	NaN	[NaN]	[487]	1	hSpCas9	negative selection	10425134
16088065	16088088	19	+	28162770	TF1	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10425135
16081992	16082015	19	-	28162770	TF1	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10425136
16093529	16093552	19	+	28162770	TF1	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10425137
16086411	16086434	19	+	28162770	TF1	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10425138
16089039	16089062	19	+	28162770	TF1	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	NaN	[NaN]	[477]	1	hSpCas9	negative selection	10425139
16088020	16088043	19	+	28162770	TF1	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	NaN	[NaN]	[282]	1	hSpCas9	negative selection	10425140
16101256	16101279	19	+	28162770	TF1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10425141
16086519	16086542	19	+	28162770	SKM1	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.31126483284145856	[30]	[67]	3	hSpCas9	negative selection	10594499
16067648	16067671	19	+	28162770	SKM1	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.4330399170582575	[180]	[431]	4	hSpCas9	negative selection	10594500
16088065	16088088	19	+	28162770	SKM1	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-1.0443941193584534	[27]	[23]	-6	hSpCas9	negative selection	10594501
16081992	16082015	19	-	28162770	SKM1	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.6200028488571078	[52]	[143]	6	hSpCas9	negative selection	10594502
16093529	16093552	19	+	28162770	SKM1	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	1.0801509785798502	[60]	[227]	8	hSpCas9	negative selection	10594503
16086411	16086434	19	+	28162770	SKM1	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10594504
16089039	16089062	19	+	28162770	SKM1	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.15642073709256477	[173]	[275]	-1	hSpCas9	negative selection	10594505
16088020	16088043	19	+	28162770	SKM1	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	1.6054195257126707	[28]	[155]	9	hSpCas9	negative selection	10594506
16101256	16101279	19	+	28162770	SKM1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.1650592462704962	[55]	[110]	1	hSpCas9	negative selection	10594507
16086519	16086542	19	+	28162770	SKM1	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.31126483284145856	[30]	[67]	3	hSpCas9	negative selection	10763865
16067648	16067671	19	+	28162770	SKM1	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.4330399170582575	[180]	[431]	4	hSpCas9	negative selection	10763866
16088065	16088088	19	+	28162770	SKM1	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-1.0443941193584534	[27]	[23]	-6	hSpCas9	negative selection	10763867
16081992	16082015	19	-	28162770	SKM1	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.6200028488571078	[52]	[143]	6	hSpCas9	negative selection	10763868
16093529	16093552	19	+	28162770	SKM1	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	1.0801509785798502	[60]	[227]	8	hSpCas9	negative selection	10763869
16086411	16086434	19	+	28162770	SKM1	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10763870
16089039	16089062	19	+	28162770	SKM1	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.15642073709256477	[173]	[275]	-1	hSpCas9	negative selection	10763871
16088020	16088043	19	+	28162770	SKM1	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	1.6054195257126707	[28]	[155]	9	hSpCas9	negative selection	10763872
16101256	16101279	19	+	28162770	SKM1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.1650592462704962	[55]	[110]	1	hSpCas9	negative selection	10763873
16086519	16086542	19	+	28162770	PL21	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.16060772928857014	[112]	[43]	-1	hSpCas9	negative selection	10933231
16067648	16067671	19	+	28162770	PL21	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	-0.042716909406843584	[638]	[269]	0	hSpCas9	negative selection	10933232
16088065	16088088	19	+	28162770	PL21	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-2.9373639092606147	[87]	[4]	-9	hSpCas9	negative selection	10933233
16081992	16082015	19	-	28162770	PL21	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.35338587478500216	[231]	[128]	3	hSpCas9	negative selection	10933234
16093529	16093552	19	+	28162770	PL21	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.03400619220938206	[284]	[126]	0	hSpCas9	negative selection	10933235
16086411	16086434	19	+	28162770	PL21	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.37347121737488187	[93]	[52]	3	hSpCas9	negative selection	10933236
16089039	16089062	19	+	28162770	PL21	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.4908167753922428	[447]	[273]	4	hSpCas9	negative selection	10933237
16088020	16088043	19	+	28162770	PL21	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	-0.3848228862318363	[152]	[50]	-3	hSpCas9	negative selection	10933238
16101256	16101279	19	+	28162770	PL21	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.2225514573329588	[251]	[46]	-7	hSpCas9	negative selection	10933239
16086519	16086542	19	+	28162770	P31FUJ	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.4500329206350475	[92]	[79]	-4	hSpCas9	negative selection	11102597
16067648	16067671	19	+	28162770	P31FUJ	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.01836659334224855	[935]	[1113]	0	hSpCas9	negative selection	11102598
16088065	16088088	19	+	28162770	P31FUJ	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.419887757014874	[73]	[64]	-4	hSpCas9	negative selection	11102599
16081992	16082015	19	-	28162770	P31FUJ	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.9705259552951476	[184]	[425]	9	hSpCas9	negative selection	11102600
16093529	16093552	19	+	28162770	P31FUJ	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.9570223544656384	[191]	[437]	9	hSpCas9	negative selection	11102601
16086411	16086434	19	+	28162770	P31FUJ	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.33518721770306414	[113]	[168]	3	hSpCas9	negative selection	11102602
16089039	16089062	19	+	28162770	P31FUJ	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.23523227239718003	[607]	[840]	2	hSpCas9	negative selection	11102603
16088020	16088043	19	+	28162770	P31FUJ	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.2783962416347231	[213]	[304]	3	hSpCas9	negative selection	11102604
16101256	16101279	19	+	28162770	P31FUJ	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-1.1186311844950676	[254]	[137]	-7	hSpCas9	negative selection	11102605
16086519	16086542	19	+	28162770	OCIAML5	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.03427664734043612	[32]	[60]	0	hSpCas9	negative selection	11271963
16067648	16067671	19	+	28162770	OCIAML5	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	-0.23934840374545896	[428]	[655]	-2	hSpCas9	negative selection	11271964
16088065	16088088	19	+	28162770	OCIAML5	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-3.0219915723063098	[71]	[15]	-8	hSpCas9	negative selection	11271965
16081992	16082015	19	-	28162770	OCIAML5	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.4364385224859151	[130]	[319]	4	hSpCas9	negative selection	11271966
16093529	16093552	19	+	28162770	OCIAML5	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.0947627701146656	[151]	[292]	0	hSpCas9	negative selection	11271967
16086411	16086434	19	+	28162770	OCIAML5	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.238421315438756	[82]	[126]	-2	hSpCas9	negative selection	11271968
16089039	16089062	19	+	28162770	OCIAML5	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.5276883847437457	[352]	[441]	-4	hSpCas9	negative selection	11271969
16088020	16088043	19	+	28162770	OCIAML5	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.41096783496979666	[124]	[299]	3	hSpCas9	negative selection	11271970
16101256	16101279	19	+	28162770	OCIAML5	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.91346817549898	[94]	[322]	7	hSpCas9	negative selection	11271971
16086519	16086542	19	+	28162770	EOL1	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.3681544230461495	[174]	[118]	3	hSpCas9	negative selection	11441329
16067648	16067671	19	+	28162770	EOL1	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.08037257596799297	[753]	[419]	0	hSpCas9	negative selection	11441330
16088065	16088088	19	+	28162770	EOL1	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.9948337682211811	[173]	[45]	-6	hSpCas9	negative selection	11441331
16081992	16082015	19	-	28162770	EOL1	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	-0.30865140472249614	[401]	[170]	-2	hSpCas9	negative selection	11441332
16093529	16093552	19	+	28162770	EOL1	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	-0.3307092836715401	[443]	[185]	-2	hSpCas9	negative selection	11441333
16086411	16086434	19	+	28162770	EOL1	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-1.5558841456793147	[172]	[30]	-7	hSpCas9	negative selection	11441334
16089039	16089062	19	+	28162770	EOL1	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.06232479444385286	[546]	[275]	0	hSpCas9	negative selection	11441335
16088020	16088043	19	+	28162770	EOL1	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.2140543887655194	[197]	[120]	2	hSpCas9	negative selection	11441336
16101256	16101279	19	+	28162770	EOL1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.30563793892604074	[257]	[167]	2	hSpCas9	negative selection	11441337
16086519	16086542	19	+	28162770	MOLM13	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.821617235650406	[153]	[62]	-4	hSpCas9	negative selection	11610695
16067648	16067671	19	+	28162770	MOLM13	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.30216681546782764	[856]	[763]	2	hSpCas9	negative selection	11610696
16088065	16088088	19	+	28162770	MOLM13	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-3.068163518695631	[115]	[9]	-8	hSpCas9	negative selection	11610697
16081992	16082015	19	-	28162770	MOLM13	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	1.1459612866572162	[284]	[455]	8	hSpCas9	negative selection	11610698
16093529	16093552	19	+	28162770	MOLM13	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.45437457507009715	[428]	[424]	3	hSpCas9	negative selection	11610699
16086411	16086434	19	+	28162770	MOLM13	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	1.4076718587104722	[158]	[304]	9	hSpCas9	negative selection	11610700
16089039	16089062	19	+	28162770	MOLM13	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.2780648226645617	[583]	[511]	2	hSpCas9	negative selection	11610701
16088020	16088043	19	+	28162770	MOLM13	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.8813300958890931	[225]	[300]	6	hSpCas9	negative selection	11610702
16101256	16101279	19	+	28162770	MOLM13	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.241520490101066	[241]	[147]	-1	hSpCas9	negative selection	11610703
16086519	16086542	19	+	28162770	HEL	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	1.2995942512032987	[136]	[215]	9	hSpCas9	negative selection	11780061
16067648	16067671	19	+	28162770	HEL	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.26478127456956324	[780]	[600]	2	hSpCas9	negative selection	11780062
16088065	16088088	19	+	28162770	HEL	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	0.40173073249656177	[90]	[76]	3	hSpCas9	negative selection	11780063
16081992	16082015	19	-	28162770	HEL	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	1.652324880829555	[224]	[452]	9	hSpCas9	negative selection	11780064
16093529	16093552	19	+	28162770	HEL	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.2513138899434636	[302]	[230]	2	hSpCas9	negative selection	11780065
16086411	16086434	19	+	28162770	HEL	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.07896000551253873	[187]	[113]	0	hSpCas9	negative selection	11780066
16089039	16089062	19	+	28162770	HEL	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.7242128932068603	[567]	[600]	6	hSpCas9	negative selection	11780067
16088020	16088043	19	+	28162770	HEL	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	-0.6285631898170374	[209]	[86]	-4	hSpCas9	negative selection	11780068
16101256	16101279	19	+	28162770	HEL	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.6941670708073598	[247]	[256]	6	hSpCas9	negative selection	11780069
16086519	16086542	19	+	28162770	MV411	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.18706493280329373	[121]	[116]	1	hSpCas9	negative selection	11949427
16067648	16067671	19	+	28162770	MV411	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.23781954822117823	[601]	[597]	2	hSpCas9	negative selection	11949428
16088065	16088088	19	+	28162770	MV411	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-0.7013371258620515	[82]	[42]	-5	hSpCas9	negative selection	11949429
16081992	16082015	19	-	28162770	MV411	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.2553427488681216	[181]	[182]	2	hSpCas9	negative selection	11949430
16093529	16093552	19	+	28162770	MV411	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.734934242068314	[198]	[278]	6	hSpCas9	negative selection	11949431
16086411	16086434	19	+	28162770	MV411	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.3708199662880574	[111]	[121]	3	hSpCas9	negative selection	11949432
16089039	16089062	19	+	28162770	MV411	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.6902416894673391	[475]	[646]	6	hSpCas9	negative selection	11949433
16088020	16088043	19	+	28162770	MV411	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	0.9054635136936546	[153]	[242]	7	hSpCas9	negative selection	11949434
16101256	16101279	19	+	28162770	MV411	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.49232667673610425	[171]	[102]	-4	hSpCas9	negative selection	11949435
16086519	16086542	19	+	28162770	MONOMAC1	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.23656521124619134	[73]	[71]	-2	hSpCas9	negative selection	12118793
16067648	16067671	19	+	28162770	MONOMAC1	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.42087607546288885	[403]	[619]	4	hSpCas9	negative selection	12118794
16088065	16088088	19	+	28162770	MONOMAC1	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	-1.2932521623188566	[61]	[28]	-7	hSpCas9	negative selection	12118795
16081992	16082015	19	-	28162770	MONOMAC1	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.04327748227415673	[159]	[188]	0	hSpCas9	negative selection	12118796
16093529	16093552	19	+	28162770	MONOMAC1	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	-0.09012164314304183	[181]	[195]	-1	hSpCas9	negative selection	12118797
16086411	16086434	19	+	28162770	MONOMAC1	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	-0.12992265120101676	[83]	[87]	-1	hSpCas9	negative selection	12118798
16089039	16089062	19	+	28162770	MONOMAC1	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.1963055811199712	[267]	[351]	2	hSpCas9	negative selection	12118799
16088020	16088043	19	+	28162770	MONOMAC1	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	1.4836846364670333	[67]	[217]	9	hSpCas9	negative selection	12118800
16101256	16101279	19	+	28162770	MONOMAC1	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	1.2857452588551244	[116]	[326]	9	hSpCas9	negative selection	12118801
16086519	16086542	19	+	28162770	OCIAML2	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	0.790635487738577	[16]	[162]	7	hSpCas9	negative selection	12288159
16067648	16067671	19	+	28162770	OCIAML2	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.5110383519855815	[98]	[781]	5	hSpCas9	negative selection	12288160
16088065	16088088	19	+	28162770	OCIAML2	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	1.4648299225631283	[9]	[152]	9	hSpCas9	negative selection	12288161
16081992	16082015	19	-	28162770	OCIAML2	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.5059112019338499	[30]	[243]	5	hSpCas9	negative selection	12288162
16093529	16093552	19	+	28162770	OCIAML2	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	0.2082328143604767	[56]	[364]	2	hSpCas9	negative selection	12288163
16086411	16086434	19	+	28162770	OCIAML2	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	0.4642751465359538	[16]	[129]	4	hSpCas9	negative selection	12288164
16089039	16089062	19	+	28162770	OCIAML2	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	0.38368085524499085	[94]	[686]	3	hSpCas9	negative selection	12288165
16088020	16088043	19	+	28162770	OCIAML2	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	1.1440800188730469	[19]	[244]	9	hSpCas9	negative selection	12288166
16101256	16101279	19	+	28162770	OCIAML2	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	-0.31682448916312583	[39]	[177]	-3	hSpCas9	negative selection	12288167
16086519	16086542	19	+	28162770	OCIAML3	viability	GGCTGACCGCAAATACGAGGAGG	TPM4	ENSG00000167460	-0.3022415159470533	[28]	[70]	-2	hSpCas9	negative selection	12457525
16067648	16067671	19	+	28162770	OCIAML3	viability	GCAGATGCTGAAGTTGGACAAGG	TPM4	ENSG00000167460	0.09289764937914402	[172]	[556]	0	hSpCas9	negative selection	12457526
16088065	16088088	19	+	28162770	OCIAML3	viability	GAGGGCAGAGGAGCGTGCGGAGG	TPM4	ENSG00000167460	0.9055633691663484	[28]	[163]	7	hSpCas9	negative selection	12457527
16081992	16082015	19	-	28162770	OCIAML3	viability	CTCCAGCTTCTGCAGGGCCGTGG	TPM4	ENSG00000167460	0.6439816360633032	[45]	[216]	6	hSpCas9	negative selection	12457528
16093529	16093552	19	+	28162770	OCIAML3	viability	CCCACAGTATTCTGAAAAGGAGG	TPM4	ENSG00000167460	-0.1070202991663044	[65]	[184]	-1	hSpCas9	negative selection	12457529
16086411	16086434	19	+	28162770	OCIAML3	viability	TGCTCCTTGCAGAGGAATGAAGG	TPM4	ENSG00000167460	2.324855596950431	[23]	[362]	9	hSpCas9	negative selection	12457530
16089039	16089062	19	+	28162770	OCIAML3	viability	GTGCAGAAAATGTGGTGACCTGG	TPM4	ENSG00000167460	-0.4637512543728216	[126]	[277]	-4	hSpCas9	negative selection	12457531
16088020	16088043	19	+	28162770	OCIAML3	viability	TCTGCAGGTAGCTCGTAAGCTGG	TPM4	ENSG00000167460	-0.20009343261107337	[42]	[112]	-1	hSpCas9	negative selection	12457532
16101256	16101279	19	+	28162770	OCIAML3	viability	CTCACCAGAGAAACTTGCCCAGG	TPM4	ENSG00000167460	0.2338113842931564	[39]	[141]	2	hSpCas9	negative selection	12457533