Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11277
• Symbol: TREX1
• Description: three prime repair exonuclease 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TREX1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48465035	48465058	3	+	26472758	Jiyoye	viability	GGGGTCAGCATGCTCATCCGAGG	TREX1	ENSG00000213689	-2.840752131937712	[132]	[13]	-9	hSpCas9	negative selection	12911
48467523	48467546	3	-	26472758	Jiyoye	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.5327062635897323	[65]	[71]	4	hSpCas9	negative selection	171775
48466766	48466789	3	+	26472758	Jiyoye	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.26777232484045693	[151]	[137]	2	hSpCas9	negative selection	171776
48466812	48466835	3	-	26472758	Jiyoye	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-0.8703585940230354	[159]	[65]	-6	hSpCas9	negative selection	171777
48466833	48466856	3	-	26472758	Jiyoye	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.8477479728918548	[41]	[56]	6	hSpCas9	negative selection	171778
48467388	48467411	3	-	26472758	Jiyoye	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.1549016705098638	[373]	[313]	1	hSpCas9	negative selection	171779
48467086	48467109	3	-	26472758	Jiyoye	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.11766876431088853	[131]	[107]	0	hSpCas9	negative selection	171780
48467104	48467127	3	-	26472758	Jiyoye	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.46783816341249757	[162]	[169]	3	hSpCas9	negative selection	171781
48467284	48467307	3	+	26472758	Jiyoye	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.0831502450772076	[117]	[83]	0	hSpCas9	negative selection	171782
48467404	48467427	3	-	26472758	Jiyoye	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.23980884582266726	[201]	[128]	-2	hSpCas9	negative selection	171783
48466736	48466759	3	-	26472758	Jiyoye	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	0.12668000560585724	[265]	[218]	1	hSpCas9	negative selection	171784
48465035	48465058	3	+	26472758	KBM7	viability	GGGGTCAGCATGCTCATCCGAGG	TREX1	ENSG00000213689	-1.7105660817208612	[251,174]	[15,42]	-8	hSpCas9	negative selection	204029
48467523	48467546	3	-	26472758	KBM7	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.16922227032184062	[460,253]	[262,113]	1	hSpCas9	negative selection	362893
48466766	48466789	3	+	26472758	KBM7	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.3990457182650115	[710,590]	[471,338]	4	hSpCas9	negative selection	362894
48466812	48466835	3	-	26472758	KBM7	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.824916730614853	[675,403]	[66,72]	-8	hSpCas9	negative selection	362895
48466833	48466856	3	-	26472758	KBM7	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.2864906800113464	[289,265]	[168,150]	3	hSpCas9	negative selection	362896
48467388	48467411	3	-	26472758	KBM7	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.029062198734766342	[1323,1154]	[717,481]	0	hSpCas9	negative selection	362897
48467086	48467109	3	-	26472758	KBM7	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.40714308701292423	[937,991]	[338,349]	-4	hSpCas9	negative selection	362898
48467104	48467127	3	-	26472758	KBM7	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.05504147299054846	[705,647]	[248,357]	0	hSpCas9	negative selection	362899
48467284	48467307	3	+	26472758	KBM7	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.7522978519261713	[584,427]	[161,119]	-6	hSpCas9	negative selection	362900
48467404	48467427	3	-	26472758	KBM7	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.24578695480403911	[538,601]	[426,226]	2	hSpCas9	negative selection	362901
48466736	48466759	3	-	26472758	KBM7	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	0.27461790554737253	[1507,1187]	[956,585]	3	hSpCas9	negative selection	362902
48465035	48465058	3	+	26472758	Raji	viability	GGGGTCAGCATGCTCATCCGAGG	TREX1	ENSG00000213689	-1.390867332154226	[112]	[9]	-7	hSpCas9	negative selection	395147
48467523	48467546	3	-	26472758	Raji	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.8178769181786149	[153]	[62]	7	hSpCas9	negative selection	554011
48466766	48466789	3	+	26472758	Raji	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.25963244904230076	[324]	[62]	-2	hSpCas9	negative selection	554012
48466812	48466835	3	-	26472758	Raji	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.10436164176334	[314]	[33]	-7	hSpCas9	negative selection	554013
48466833	48466856	3	-	26472758	Raji	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-1.1538817776071388	[162]	[16]	-7	hSpCas9	negative selection	554014
48467388	48467411	3	-	26472758	Raji	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.49022221226429497	[588]	[191]	4	hSpCas9	negative selection	554015
48467086	48467109	3	-	26472758	Raji	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.18311086153684447	[333]	[87]	1	hSpCas9	negative selection	554016
48467104	48467127	3	-	26472758	Raji	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.011805875391368625	[311]	[72]	0	hSpCas9	negative selection	554017
48467284	48467307	3	+	26472758	Raji	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.2791975178560163	[250]	[47]	-2	hSpCas9	negative selection	554018
48467404	48467427	3	-	26472758	Raji	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.5330740779392604	[317]	[50]	-4	hSpCas9	negative selection	554019
48466736	48466759	3	-	26472758	Raji	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.7220283075572018	[724]	[101]	-5	hSpCas9	negative selection	554020
48465035	48465058	3	+	26472758	K562	viability	GGGGTCAGCATGCTCATCCGAGG	TREX1	ENSG00000213689	-5.127140134945516	[206]	[4]	-9	hSpCas9	negative selection	586265
48467523	48467546	3	-	26472758	K562	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	1.7489625459323053	[165]	[470]	9	hSpCas9	negative selection	745129
48466766	48466789	3	+	26472758	K562	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.6066186332085542	[569]	[315]	-4	hSpCas9	negative selection	745130
48466812	48466835	3	-	26472758	K562	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.355131309277756	[496]	[81]	-8	hSpCas9	negative selection	745131
48466833	48466856	3	-	26472758	K562	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	1.1125532797924729	[165]	[302]	8	hSpCas9	negative selection	745132
48467388	48467411	3	-	26472758	K562	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.16896649923698148	[1098]	[1042]	1	hSpCas9	negative selection	745133
48467086	48467109	3	-	26472758	K562	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.7048704520000197	[586]	[303]	-4	hSpCas9	negative selection	745134
48467104	48467127	3	-	26472758	K562	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.6323098974318193	[638]	[347]	-4	hSpCas9	negative selection	745135
48467284	48467307	3	+	26472758	K562	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.7848755791275912	[397]	[194]	-4	hSpCas9	negative selection	745136
48467404	48467427	3	-	26472758	K562	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.999919584457442	[551]	[232]	-5	hSpCas9	negative selection	745137
48466736	48466759	3	-	26472758	K562	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.762812841564629	[1199]	[596]	-4	hSpCas9	negative selection	745138
48466576	48466599	3	-	26627737	DLD1	viability	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.0251297854813908	[456]	[186,129,121]	0	hSpCas9	negative selection	822086
48466577	48466600	3	-	26627737	DLD1	viability	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.06327893199335399	[562]	[209,188,156]	0	hSpCas9	negative selection	822087
48467050	48467073	3	-	26627737	DLD1	viability	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.8346122317013569	[1321]	[266,185,238]	-7	hSpCas9	negative selection	822088
48467414	48467437	3	-	26627737	DLD1	viability	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.2488657464743984	[210]	[89,177,196]	9	hSpCas9	negative selection	822089
48467539	48467562	3	-	26627737	DLD1	viability	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	1.7591742210926578	[150]	[172,228,90]	9	hSpCas9	negative selection	822090
48466576	48466599	3	-	26627737	GBM cells	viability after 5 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.050031607737813455	[325]	[179,181]	0	hSpCas9	negative selection	904401
48466577	48466600	3	-	26627737	GBM cells	viability after 5 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.25615552160714783	[313]	[148,132]	-4	hSpCas9	negative selection	904402
48467050	48467073	3	-	26627737	GBM cells	viability after 5 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.33977514962248284	[262]	[158,197]	5	hSpCas9	negative selection	904403
48467414	48467437	3	-	26627737	GBM cells	viability after 5 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.2780668384659979	[172]	[128,95]	4	hSpCas9	negative selection	904404
48467539	48467562	3	-	26627737	GBM cells	viability after 5 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.396940738835561	[113]	[71,88]	6	hSpCas9	negative selection	904405
48466576	48466599	3	-	26627737	GBM cells	viability after 13 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.5312866218753439	[325]	[144,103]	-6	hSpCas9	negative selection	986716
48466577	48466600	3	-	26627737	GBM cells	viability after 13 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.5393449597002103	[313]	[87,140]	-6	hSpCas9	negative selection	986717
48467050	48467073	3	-	26627737	GBM cells	viability after 13 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.5168569428644517	[262]	[212,196]	6	hSpCas9	negative selection	986718
48467414	48467437	3	-	26627737	GBM cells	viability after 13 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.18745400530815348	[172]	[91,118]	2	hSpCas9	negative selection	986719
48467539	48467562	3	-	26627737	GBM cells	viability after 13 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.21899076927994277	[113]	[55,84]	3	hSpCas9	negative selection	986720
48466576	48466599	3	-	26627737	GBM cells	viability after 21 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.4903246533699482	[325]	[135,116]	-4	hSpCas9	negative selection	1069031
48466577	48466600	3	-	26627737	GBM cells	viability after 21 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.3283397087186731	[313]	[138,132]	-3	hSpCas9	negative selection	1069032
48467050	48467073	3	-	26627737	GBM cells	viability after 21 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.5795567255477382	[262]	[212,213]	6	hSpCas9	negative selection	1069033
48467414	48467437	3	-	26627737	GBM cells	viability after 21 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.41382385304684877	[172]	[131,118]	4	hSpCas9	negative selection	1069034
48467539	48467562	3	-	26627737	GBM cells	viability after 21 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.3732733108957753	[113]	[74,84]	4	hSpCas9	negative selection	1069035
48466576	48466599	3	-	26627737	RPE1	viability after 9 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.4125024312032793	[1079]	[494,391]	3	hSpCas9	negative selection	1151346
48466577	48466600	3	-	26627737	RPE1	viability after 9 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.8809608629256345	[1616]	[311,226]	-6	hSpCas9	negative selection	1151347
48467050	48467073	3	-	26627737	RPE1	viability after 9 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.6268471353529768	[1806]	[323,420]	-4	hSpCas9	negative selection	1151348
48467414	48467437	3	-	26627737	RPE1	viability after 9 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.7135548873478386	[230]	[265,199]	8	hSpCas9	negative selection	1151349
48467539	48467562	3	-	26627737	RPE1	viability after 9 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.6743988156557985	[401]	[101,48]	-5	hSpCas9	negative selection	1151350
48466576	48466599	3	-	26627737	RPE1	viability after 12 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.35745702626159975	[1079]	[379,362]	2	hSpCas9	negative selection	1233661
48466577	48466600	3	-	26627737	RPE1	viability after 12 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.8861248405751798	[1616]	[219,250]	-6	hSpCas9	negative selection	1233662
48467050	48467073	3	-	26627737	RPE1	viability after 12 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.4386478520928627	[1806]	[415,296]	-3	hSpCas9	negative selection	1233663
48467414	48467437	3	-	26627737	RPE1	viability after 12 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.6140010156519264	[230]	[188,190]	8	hSpCas9	negative selection	1233664
48467539	48467562	3	-	26627737	RPE1	viability after 12 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.5382637000466453	[401]	[18,132]	-4	hSpCas9	negative selection	1233665
48466576	48466599	3	-	26627737	RPE1	viability after 15 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.08484372317893124	[1079]	[266,378]	0	hSpCas9	negative selection	1315976
48466577	48466600	3	-	26627737	RPE1	viability after 15 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.9400023993907785	[1616]	[242,233]	-5	hSpCas9	negative selection	1315977
48467050	48467073	3	-	26627737	RPE1	viability after 15 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.6069279754187604	[1806]	[412,260]	-4	hSpCas9	negative selection	1315978
48467414	48467437	3	-	26627737	RPE1	viability after 15 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.7199071689472942	[230]	[228,201]	8	hSpCas9	negative selection	1315979
48467539	48467562	3	-	26627737	RPE1	viability after 15 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.20747994959915195	[401]	[85,174]	1	hSpCas9	negative selection	1315980
48466576	48466599	3	-	26627737	RPE1	viability after 18 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.03337426563506124	[1079]	[218,382]	0	hSpCas9	negative selection	1398291
48466577	48466600	3	-	26627737	RPE1	viability after 18 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-1.1948018246289291	[1616]	[106,279]	-6	hSpCas9	negative selection	1398292
48467050	48467073	3	-	26627737	RPE1	viability after 18 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.9328943676038264	[1806]	[238,272]	-5	hSpCas9	negative selection	1398293
48467414	48467437	3	-	26627737	RPE1	viability after 18 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.6676901681872713	[230]	[257,133]	8	hSpCas9	negative selection	1398294
48467539	48467562	3	-	26627737	RPE1	viability after 18 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.1368776570853516	[401]	[10,234]	0	hSpCas9	negative selection	1398295
48466576	48466599	3	-	26627737	HeLa	viability after 8 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.39256759421371806	[426]	[257,279,199]	3	hSpCas9	negative selection	1480606
48466577	48466600	3	-	26627737	HeLa	viability after 8 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.7496445068660837	[305]	[211,306,154]	6	hSpCas9	negative selection	1480607
48467050	48467073	3	-	26627737	HeLa	viability after 8 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.6443280863962093	[275]	[237,100,231]	5	hSpCas9	negative selection	1480608
48467414	48467437	3	-	26627737	HeLa	viability after 8 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.3270690363012929	[257]	[169,148,111]	3	hSpCas9	negative selection	1480609
48467539	48467562	3	-	26627737	HeLa	viability after 8 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.9239787937421441	[369]	[55,118,73]	-7	hSpCas9	negative selection	1480610
48466576	48466599	3	-	26627737	HeLa	viability after 12 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.32697308074886494	[426]	[407,140,128]	3	hSpCas9	negative selection	1562921
48466577	48466600	3	-	26627737	HeLa	viability after 12 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.9511734548990801	[305]	[309,153,280]	7	hSpCas9	negative selection	1562922
48467050	48467073	3	-	26627737	HeLa	viability after 12 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	1.7813316480836803	[275]	[408,313,461]	9	hSpCas9	negative selection	1562923
48467414	48467437	3	-	26627737	HeLa	viability after 12 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	-0.12303014542284796	[257]	[131,47,119]	-1	hSpCas9	negative selection	1562924
48467539	48467562	3	-	26627737	HeLa	viability after 12 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.517610874349549	[369]	[111,83,126]	-4	hSpCas9	negative selection	1562925
48466576	48466599	3	-	26627737	HeLa	viability after 15 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.37503187494863083	[426]	[260,235,174]	3	hSpCas9	negative selection	1645236
48466577	48466600	3	-	26627737	HeLa	viability after 15 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.9376439517598122	[305]	[250,221,242]	7	hSpCas9	negative selection	1645237
48467050	48467073	3	-	26627737	HeLa	viability after 15 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	1.1410579626110338	[275]	[214,278,249]	7	hSpCas9	negative selection	1645238
48467414	48467437	3	-	26627737	HeLa	viability after 15 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.6910376398513797	[257]	[164,110,237]	5	hSpCas9	negative selection	1645239
48467539	48467562	3	-	26627737	HeLa	viability after 15 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-1.838253249436744	[369]	[32,8,87]	-9	hSpCas9	negative selection	1645240
48466576	48466599	3	-	26627737	HeLa	viability after 18 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.3669362957732385	[426]	[168,199,174]	3	hSpCas9	negative selection	1727551
48466577	48466600	3	-	26627737	HeLa	viability after 18 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.9584125125575949	[305]	[170,188,242]	7	hSpCas9	negative selection	1727552
48467050	48467073	3	-	26627737	HeLa	viability after 18 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	1.1142520545858867	[275]	[136,228,249]	7	hSpCas9	negative selection	1727553
48467414	48467437	3	-	26627737	HeLa	viability after 18 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.7134396305160087	[257]	[118,87,237]	5	hSpCas9	negative selection	1727554
48467539	48467562	3	-	26627737	HeLa	viability after 18 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-1.815608363453279	[369]	[22,7,87]	-9	hSpCas9	negative selection	1727555
48466576	48466599	3	-	26627737	HCT116	viability after 6 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.7420811003637313	[602]	[28,229]	4	hSpCas9	negative selection	1809866
48466577	48466600	3	-	26627737	HCT116	viability after 6 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.29257378907922194	[607]	[225,56]	1	hSpCas9	negative selection	1809867
48467050	48467073	3	-	26627737	HCT116	viability after 6 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	2.872821332858365	[506]	[1355,157]	9	hSpCas9	negative selection	1809868
48467414	48467437	3	-	26627737	HCT116	viability after 6 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	2.42851077993779	[148]	[60,161]	9	hSpCas9	negative selection	1809869
48467539	48467562	3	-	26627737	HCT116	viability after 6 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.5424431901774006	[658]	[30,216]	3	hSpCas9	negative selection	1809870
48466576	48466599	3	-	26627737	HCT116	viability after 8 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.1673092302836054	[350]	[181,255,212]	2	hSpCas9	negative selection	1892181
48466577	48466600	3	-	26627737	HCT116	viability after 8 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.24160658692675044	[330]	[172,124,164]	-3	hSpCas9	negative selection	1892182
48467050	48467073	3	-	26627737	HCT116	viability after 8 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.7374446543610793	[293]	[282,297,229]	7	hSpCas9	negative selection	1892183
48467414	48467437	3	-	26627737	HCT116	viability after 8 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.12740112764418576	[170]	[94,140,72]	1	hSpCas9	negative selection	1892184
48467539	48467562	3	-	26627737	HCT116	viability after 8 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	2.0344560369597167	[41]	[63,134,84]	9	hSpCas9	negative selection	1892185
48466576	48466599	3	-	26627737	HCT116	viability after 9 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.3423563253700553	[602]	[54,321]	2	hSpCas9	negative selection	1974496
48466577	48466600	3	-	26627737	HCT116	viability after 9 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	1.0010382379741178	[607]	[420,248]	7	hSpCas9	negative selection	1974497
48467050	48467073	3	-	26627737	HCT116	viability after 9 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.5050577802637554	[506]	[147,226]	4	hSpCas9	negative selection	1974498
48467414	48467437	3	-	26627737	HCT116	viability after 9 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.5208758891693712	[148]	[164,73]	8	hSpCas9	negative selection	1974499
48467539	48467562	3	-	26627737	HCT116	viability after 9 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.543615329772192	[658]	[89,144]	-4	hSpCas9	negative selection	1974500
48466576	48466599	3	-	26627737	HCT116	viability after 12 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.07883183067365362	[350]	[159,255,172]	0	hSpCas9	negative selection	2056811
48466577	48466600	3	-	26627737	HCT116	viability after 12 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.5772187055735476	[330]	[419,156,184]	5	hSpCas9	negative selection	2056812
48467050	48467073	3	-	26627737	HCT116	viability after 12 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.982490693595378	[293]	[161,534,236]	8	hSpCas9	negative selection	2056813
48467414	48467437	3	-	26627737	HCT116	viability after 12 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.3251781542728817	[170]	[110,116,109]	3	hSpCas9	negative selection	2056814
48467539	48467562	3	-	26627737	HCT116	viability after 12 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	1.5891471321642578	[41]	[54,56,87]	9	hSpCas9	negative selection	2056815
48466576	48466599	3	-	26627737	HCT116	viability after 15 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.5122039506520611	[350]	[257,321,278]	5	hSpCas9	negative selection	2139126
48466577	48466600	3	-	26627737	HCT116	viability after 15 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.08372571501461362	[330]	[323,154,140]	0	hSpCas9	negative selection	2139127
48467050	48467073	3	-	26627737	HCT116	viability after 15 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.8444369987567757	[293]	[149,531,209]	7	hSpCas9	negative selection	2139128
48467414	48467437	3	-	26627737	HCT116	viability after 15 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	-0.1200737099191116	[170]	[78,124,65]	-1	hSpCas9	negative selection	2139129
48467539	48467562	3	-	26627737	HCT116	viability after 15 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	1.2952307576965347	[41]	[72,24,80]	8	hSpCas9	negative selection	2139130
48466576	48466599	3	-	26627737	HCT116	viability after 18 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.7057543617116697	[350]	[204,265,363]	6	hSpCas9	negative selection	2221441
48466577	48466600	3	-	26627737	HCT116	viability after 18 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.5985882426772164	[330]	[312,246,162]	5	hSpCas9	negative selection	2221442
48467050	48467073	3	-	26627737	HCT116	viability after 18 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.9223763927917231	[293]	[130,412,253]	7	hSpCas9	negative selection	2221443
48467414	48467437	3	-	26627737	HCT116	viability after 18 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	-0.07618685348573218	[170]	[44,119,66]	0	hSpCas9	negative selection	2221444
48467539	48467562	3	-	26627737	HCT116	viability after 18 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	1.3285883448979803	[41]	[85,27,39]	8	hSpCas9	negative selection	2221445
48466717	48466740	3	-	24336569	HL60	viability	CTGGGAGAAGGGCAAGCCAGTGG	TREX1	ENSG00000213689	-0.7202493008561992	[1064]	[1367]	-6	hSpCas9	negative selection	2303331
48466728	48466751	3	-	24336569	HL60	viability	GTGACCTTGGGCTGGGAGAAGGG	TREX1	ENSG00000213689	1.2968278953378456	[757]	[3940]	8	hSpCas9	negative selection	2303332
48466735	48466758	3	-	24336569	HL60	viability	CAGCTCCGTGACCTTGGGCTGGG	TREX1	ENSG00000213689	-0.17063461030614213	[950]	[1787]	-1	hSpCas9	negative selection	2303333
48466740	48466763	3	-	24336569	HL60	viability	AGGCACAGCTCCGTGACCTTGGG	TREX1	ENSG00000213689	-0.05878371148809591	[851]	[1730]	0	hSpCas9	negative selection	2303334
48466745	48466768	3	+	24336569	HL60	viability	GGTCACGGAGCTGTGCCTGCTGG	TREX1	ENSG00000213689	-0.11827676624662331	[257]	[502]	-1	hSpCas9	negative selection	2303335
48466760	48466783	3	-	24336569	HL60	viability	CACATCTGTGGACAGCCAGCAGG	TREX1	ENSG00000213689	-0.9796618201060368	[423]	[454]	-7	hSpCas9	negative selection	2303336
48466766	48466789	3	+	24336569	HL60	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.5221541993725838	[460]	[1400]	4	hSpCas9	negative selection	2303337
48466772	48466795	3	-	24336569	HL60	viability	GGCTCTCCAGGGCACATCTGTGG	TREX1	ENSG00000213689	-0.7530422436560338	[265]	[333]	-6	hSpCas9	negative selection	2303338
48466812	48466835	3	-	24336569	HL60	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.5625301334233401	[990]	[709]	-8	hSpCas9	negative selection	2303339
48466818	48466841	3	-	24336569	HL60	viability	CGCGGTGGTGGAGGAACTGTGGG	TREX1	ENSG00000213689	-1.120812768104722	[445]	[433]	-7	hSpCas9	negative selection	2303340
48466717	48466740	3	-	24336569	KBM7	viability	CTGGGAGAAGGGCAAGCCAGTGG	TREX1	ENSG00000213689	-0.9473454629916445	[636]	[900]	-6	hSpCas9	negative selection	2370508
48466728	48466751	3	-	24336569	KBM7	viability	GTGACCTTGGGCTGGGAGAAGGG	TREX1	ENSG00000213689	-0.3525467479259439	[491]	[1050]	-3	hSpCas9	negative selection	2370509
48466735	48466758	3	-	24336569	KBM7	viability	CAGCTCCGTGACCTTGGGCTGGG	TREX1	ENSG00000213689	-0.045535594748242425	[710]	[1878]	0	hSpCas9	negative selection	2370510
48466740	48466763	3	-	24336569	KBM7	viability	AGGCACAGCTCCGTGACCTTGGG	TREX1	ENSG00000213689	-0.1294627156115391	[757]	[1889]	-1	hSpCas9	negative selection	2370511
48466745	48466768	3	+	24336569	KBM7	viability	GGTCACGGAGCTGTGCCTGCTGG	TREX1	ENSG00000213689	0.5999939563692499	[260]	[1078]	5	hSpCas9	negative selection	2370512
48466760	48466783	3	-	24336569	KBM7	viability	CACATCTGTGGACAGCCAGCAGG	TREX1	ENSG00000213689	-0.9678360078822235	[326]	[455]	-6	hSpCas9	negative selection	2370513
48466766	48466789	3	+	24336569	KBM7	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.9853987138708957	[571]	[787]	-6	hSpCas9	negative selection	2370514
48466772	48466795	3	-	24336569	KBM7	viability	GGCTCTCCAGGGCACATCTGTGG	TREX1	ENSG00000213689	-0.5112378337712002	[138]	[265]	-4	hSpCas9	negative selection	2370515
48466812	48466835	3	-	24336569	KBM7	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.1611618632771377	[509]	[310]	-8	hSpCas9	negative selection	2370516
48466818	48466841	3	-	24336569	KBM7	viability	CGCGGTGGTGGAGGAACTGTGGG	TREX1	ENSG00000213689	0.5806176952817694	[265]	[1084]	5	hSpCas9	negative selection	2370517
48465371	48465394	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	AACCAGTCCCTTCCACACCCAGG	TREX1	ENSG00000213689	0.27766632122663304	[66,77]	[7,30]	1	dCas9-VP64	positive selection	2447873
48465422	48465445	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGGACCTGCCCTAGGCCCTGG	TREX1	ENSG00000213689	-1.7940840572598216	[58,121]	[3,6]	-8	dCas9-VP64	positive selection	2447874
48465398	48465421	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCTCCCCCAACGTCCGCAGG	TREX1	ENSG00000213689	0.9194633876869518	[581,410]	[375,22]	4	dCas9-VP64	positive selection	2447875
48465371	48465394	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	AACCAGTCCCTTCCACACCCAGG	TREX1	ENSG00000213689	-0.18837474017870814	[191,258]	[77,51]	-2	dCas9-VP64	positive selection	2543128
48465422	48465445	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGGACCTGCCCTAGGCCCTGG	TREX1	ENSG00000213689	-0.7651030192960651	[452,72]	[26,72]	-7	dCas9-VP64	positive selection	2543129
48465398	48465421	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCTCCCCCAACGTCCGCAGG	TREX1	ENSG00000213689	-0.03300606739098022	[244,563]	[66,185]	0	dCas9-VP64	positive selection	2543130
48466790	48466813	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	0.09201148595888042	[4,4]	[3,4]	2	hSpCas9	positive selection	3029035
48466693	48466716	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	0.35616808470760175	[4,3]	[3,5]	7	hSpCas9	positive selection	3029036
48466836	48466859	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.32203235667112545	[3,3]	[2,0]	-4	hSpCas9	positive selection	3029037
48467007	48467030	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	-0.3941929684186783	[3,3]	[4,0]	-5	hSpCas9	positive selection	3029038
48466790	48466813	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	-0.18938662853901506	[4,4]	[4,1]	-3	hSpCas9	positive selection	3096893
48466693	48466716	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	-0.044693064623768125	[4,4]	[3,2]	0	hSpCas9	positive selection	3096894
48466836	48466859	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.3247961573057258	[3,3]	[3,0]	-5	hSpCas9	positive selection	3096895
48467007	48467030	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	-0.07014860529458418	[3,3]	[3,1]	-1	hSpCas9	positive selection	3096896
48467196	48467219		+	24336571	A375	resistance to PLX after 7 days	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.07029130288515062	[30,26]	[26,27]	-2	hSpCas9	positive selection	3152494
48466823	48466846		+	24336571	A375	resistance to PLX after 7 days	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.1617665072043013	[29,28]	[33,30]	5	hSpCas9	positive selection	3152495
48467229	48467252		-	24336571	A375	resistance to PLX after 7 days	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	-0.16204048639985508	[13,12]	[11,11]	-5	hSpCas9	positive selection	3152496
48467196	48467219		+	24336571	A375	resistance to PLX after 14 days	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.7070003149802808	[31,23]	[6,7]	-8	hSpCas9	positive selection	3210287
48466823	48466846		+	24336571	A375	resistance to PLX after 14 days	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.4747468972382015	[34,28]	[9,10]	-5	hSpCas9	positive selection	3210288
48467229	48467252		-	24336571	A375	resistance to PLX after 14 days	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	-0.32151886597668294	[13,10]	[4,3]	-4	hSpCas9	positive selection	3210289
48467196	48467219		+	24336571	A375	viability after 7 days	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.49011191082583283	[21]	[30,26]	7	hSpCas9	negative selection	3268080
48466823	48466846		+	24336571	A375	viability after 7 days	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.01752974724687717	[30]	[29,28]	0	hSpCas9	negative selection	3268081
48467229	48467252		-	24336571	A375	viability after 7 days	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.3725003955881123	[10]	[13,12]	5	hSpCas9	negative selection	3268082
48467196	48467219		+	24336571	A375	viability after 14 days	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.42379066705772106	[21]	[31,23]	5	hSpCas9	negative selection	3325873
48466823	48466846		+	24336571	A375	viability after 14 days	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.14758322327457263	[30]	[34,28]	2	hSpCas9	negative selection	3325874
48467229	48467252		-	24336571	A375	viability after 14 days	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2704205330503662	[10]	[13,10]	3	hSpCas9	negative selection	3325875
48467114	48467137	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3398909
48467222	48467245	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.25732621144583506	[127,127]	[0,0]	1	hSpCas9	positive selection	3398910
48466836	48466859	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.5628527509693527	[225,225]	[0,0]	-4	hSpCas9	positive selection	3398911
48466789	48466812	3	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	0.245134425750517	[]	[]	0	hSpCas9	negative selection	3467883
48466693	48466716	3	-	26780180	HT29	viability (Avana library 4 designs)	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	1.52743226049138	[]	[]	6	hSpCas9	negative selection	3467884
48466836	48466859	3	-	26780180	HT29	viability (Avana library 4 designs)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	1.19690036141252	[]	[]	4	hSpCas9	negative selection	3467885
48467007	48467030	3	-	26780180	HT29	viability (Avana library 4 designs)	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	0.760784280196099	[]	[]	3	hSpCas9	negative selection	3467886
48466836	48466859	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	2.46714052163052	[]	[]	3	hSpCas9	negative selection	3572270
48467007	48467030	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	2.37313152951713	[]	[]	3	hSpCas9	negative selection	3572271
48466693	48466716	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	2.18865484197178	[]	[]	3	hSpCas9	negative selection	3572272
48466789	48466812	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	4.92638744599582	[]	[]	8	hSpCas9	negative selection	3572273
48466855	48466878	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCCCTGTGTGTGGCTCCGGGG	TREX1	ENSG00000213689	-1.60677879143552	[]	[]	-2	hSpCas9	negative selection	3572274
48466897	48466920	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAGACCTGTGATCTCGCTGG	TREX1	ENSG00000213689	2.13788311463542	[]	[]	3	hSpCas9	negative selection	3572275
48466836	48466859	3	-	26780180	A375	viability (Avana lentiGuide)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	3.70686070505028	[]	[]	3	hSpCas9	negative selection	3680929
48467007	48467030	3	-	26780180	A375	viability (Avana lentiGuide)	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	-3.49224673660112	[]	[]	-6	hSpCas9	negative selection	3680930
48466693	48466716	3	-	26780180	A375	viability (Avana lentiGuide)	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	-0.593033151132932	[]	[]	-1	hSpCas9	negative selection	3680931
48466789	48466812	3	+	26780180	A375	viability (Avana lentiGuide)	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	0.146302751415866	[]	[]	0	hSpCas9	negative selection	3680932
48466855	48466878	3	+	26780180	A375	viability (Avana lentiGuide)	TCTCCCTGTGTGTGGCTCCGGGG	TREX1	ENSG00000213689	11.5627185219032	[]	[]	7	hSpCas9	negative selection	3680933
48466897	48466920	3	-	26780180	A375	viability (Avana lentiGuide)	GCTCAGACCTGTGATCTCGCTGG	TREX1	ENSG00000213689	2.22532841298941	[]	[]	2	hSpCas9	negative selection	3680934
48466836	48466859	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.17160323346457268	[4]	[5,4]	5	hSpCas9	positive selection	3789536
48467007	48467030	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	0.15302281948183422	[5]	[5,5]	4	hSpCas9	positive selection	3789537
48466693	48466716	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	-0.24085329206525452	[5]	[3,4]	-4	hSpCas9	positive selection	3789538
48466789	48466812	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	0.2893330652688386	[5]	[7,6]	8	hSpCas9	positive selection	3789539
48466855	48466878	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCCCTGTGTGTGGCTCCGGGG	TREX1	ENSG00000213689	-0.45732265054904264	[1]	[0,0]	-6	hSpCas9	positive selection	3789540
48466897	48466920	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAGACCTGTGATCTCGCTGG	TREX1	ENSG00000213689	-0.5029321703278233	[4]	[1,3]	-6	hSpCas9	positive selection	3789541
48466836	48466859	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.4128772473264611	[4]	[3,1]	-5	hSpCas9	positive selection	3898143
48467007	48467030	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTGTGCCACCAGGCACCAGGG	TREX1	ENSG00000213689	-0.4158826168389143	[5]	[2,3]	-5	hSpCas9	positive selection	3898144
48466693	48466716	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCCATGTCGAAAAAGATGAGGG	TREX1	ENSG00000213689	0.2611924247534218	[5]	[6,5]	7	hSpCas9	positive selection	3898145
48466789	48466812	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCCCCCCCACCTCTCAGGGG	TREX1	ENSG00000213689	0.3678397352281338	[6]	[6,7]	9	hSpCas9	positive selection	3898146
48466855	48466878	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCCCTGTGTGTGGCTCCGGGG	TREX1	ENSG00000213689	-1.2371079375703928	[1]	[0,0]	-9	hSpCas9	positive selection	3898147
48466897	48466920	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAGACCTGTGATCTCGCTGG	TREX1	ENSG00000213689	0.1869930116434811	[5]	[5,4]	4	hSpCas9	positive selection	3898148
48467196	48467219	3	+	26780180	A375	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.826842636351706	[]	[]	3	hSpCas9	negative selection	4007480
48466823	48466846	3	+	26780180	A375	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	1.20264027382062	[]	[]	6	hSpCas9	negative selection	4007481
48467229	48467252	3	-	26780180	A375	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	1.39367031502627	[]	[]	7	hSpCas9	negative selection	4007482
48466836	48466859	3	-	26780180	A375	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	1.44788133435732	[]	[]	8	hSpCas9	negative selection	4007483
48467114	48467137	3	+	26780180	A375	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	1.60323523412028	[]	[]	8	hSpCas9	negative selection	4007484
48467222	48467245	3	+	26780180	A375	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.460108421598955	[]	[]	1	hSpCas9	negative selection	4007485
48467196	48467219	3	+	26780180	HT29	viability (GeCKOv2 library)	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	1.04774061288352	[]	[]	5	hSpCas9	negative selection	4115446
48466823	48466846	3	+	26780180	HT29	viability (GeCKOv2 library)	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	1.01429607537974	[]	[]	4	hSpCas9	negative selection	4115447
48467229	48467252	3	-	26780180	HT29	viability (GeCKOv2 library)	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.760623679856178	[]	[]	3	hSpCas9	negative selection	4115448
48466836	48466859	3	-	26780180	HT29	viability (GeCKOv2 library)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.914047766922219	[]	[]	4	hSpCas9	negative selection	4115449
48467114	48467137	3	+	26780180	HT29	viability (GeCKOv2 library)	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	1.89065851739388	[]	[]	9	hSpCas9	negative selection	4115450
48467222	48467245	3	+	26780180	HT29	viability (GeCKOv2 library)	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.63227085547278	[]	[]	2	hSpCas9	negative selection	4115451
48467196	48467219	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.0251445300614348	[5]	[3,2]	0	hSpCas9	positive selection	4179049
48466823	48466846	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.010527130042402633	[4]	[3,3]	0	hSpCas9	positive selection	4179050
48467229	48467252	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.05506602783496405	[3]	[2,1]	1	hSpCas9	positive selection	4179051
48467196	48467219	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.003465368309257588	[4]	[1,3,3,0]	0	hSpCas9	positive selection	4243071
48466823	48466846	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	1.3026118216629026	[4]	[5,4,5,5]	9	hSpCas9	positive selection	4243072
48467229	48467252	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.5011128261214259	[2]	[3,3,0,0]	3	hSpCas9	positive selection	4243073
48467196	48467219	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.6935904059029662	[2]	[4,4]	9	hSpCas9	positive selection	4304993
48466823	48466846	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.19578678675850236	[4]	[4,3]	4	hSpCas9	positive selection	4304994
48467229	48467252	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.1905359798162554	[3]	[3,2]	4	hSpCas9	positive selection	4304995
48467114	48467137	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.799553157328649	[2]	[1,0]	-9	hSpCas9	positive selection	4369241
48467222	48467245	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.25043245370157086	[2]	[2,0]	-5	hSpCas9	positive selection	4369242
48466836	48466859	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.40088680045320196	[3]	[2,1]	-7	hSpCas9	positive selection	4369243
48466830	48466852	3	-	27760321	OCIAML3	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	0.2199899341677466	[782,812]	[775,670]	2	hSpCas9	negative selection	4449857
48466922	48466944	3	+	27760321	OCIAML3	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.5923179708936298	[457,412]	[114,369]	-5	hSpCas9	negative selection	4449858
48467015	48467037	3	-	27760321	OCIAML3	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	-0.06998504423156682	[1057,874]	[491,1009]	-1	hSpCas9	negative selection	4449859
48467036	48467058	3	-	27760321	OCIAML3	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.7389114665904104	[315,236]	[290,444]	8	hSpCas9	negative selection	4449860
48467230	48467252	3	+	27760321	OCIAML3	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.21765722447634284	[697,632]	[530,700]	2	hSpCas9	negative selection	4449861
48466830	48466852	3	-	27760321	OCIAML2	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.08027642524120904	[782,812]	[531,720]	-1	hSpCas9	negative selection	4533320
48466922	48466944	3	+	27760321	OCIAML2	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.32763877402332614	[457,412]	[254,313]	-4	hSpCas9	negative selection	4533321
48467015	48467037	3	-	27760321	OCIAML2	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.08009465995021037	[1057,874]	[707,973]	1	hSpCas9	negative selection	4533322
48467036	48467058	3	-	27760321	OCIAML2	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.03218020784870024	[315,236]	[152,323]	0	hSpCas9	negative selection	4533323
48467230	48467252	3	+	27760321	OCIAML2	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	-0.1372752104696484	[697,632]	[467,516]	-2	hSpCas9	negative selection	4533324
48466830	48466852	3	-	27760321	MV411	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-1.1147282811150725	[782,812]	[179,340]	-6	hSpCas9	negative selection	4616783
48466922	48466944	3	+	27760321	MV411	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	0.18416153252907422	[457,412]	[330,318]	1	hSpCas9	negative selection	4616784
48467015	48467037	3	-	27760321	MV411	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.3096696028068562	[1057,874]	[967,514]	2	hSpCas9	negative selection	4616785
48467036	48467058	3	-	27760321	MV411	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	1.808966671095662	[315,236]	[796,388]	9	hSpCas9	negative selection	4616786
48467230	48467252	3	+	27760321	MV411	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.6828566955108599	[697,632]	[807,548]	5	hSpCas9	negative selection	4616787
48466830	48466852	3	-	27760321	HL60	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.1955545410478906	[782,812]	[587,554]	-2	hSpCas9	negative selection	4700246
48466922	48466944	3	+	27760321	HL60	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.23531428687271963	[457,412]	[232,374]	-3	hSpCas9	negative selection	4700247
48467015	48467037	3	-	27760321	HL60	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.5990658237837387	[1057,874]	[1141,1241]	7	hSpCas9	negative selection	4700248
48467036	48467058	3	-	27760321	HL60	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.4701774688490785	[315,236]	[334,283]	6	hSpCas9	negative selection	4700249
48467230	48467252	3	+	27760321	HL60	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.45003011449652774	[697,632]	[761,720]	5	hSpCas9	negative selection	4700250
48466830	48466852	3	-	27760321	HT1080	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	0.44014882716023895	[812,634]	[176,625]	2	hSpCas9	negative selection	4783709
48466922	48466944	3	+	27760321	HT1080	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.8716377617863849	[412,321]	[37,125]	-4	hSpCas9	negative selection	4783710
48467015	48467037	3	-	27760321	HT1080	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.4997036667922996	[874,682]	[349,535]	2	hSpCas9	negative selection	4783711
48467036	48467058	3	-	27760321	HT1080	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.22540855414927086	[236,184]	[103,91]	1	hSpCas9	negative selection	4783712
48467230	48467252	3	+	27760321	HT1080	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	1.2438034329914456	[632,493]	[491,574]	6	hSpCas9	negative selection	4783713
48466830	48466852	3	-	27760321	HT29	viability after 7 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.3525307511699075	[812,634]	[934,596,684]	-5	hSpCas9	negative selection	4867172
48466922	48466944	3	+	27760321	HT29	viability after 7 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	0.187289299350421	[412,321]	[381,515,687]	3	hSpCas9	negative selection	4867173
48467015	48467037	3	-	27760321	HT29	viability after 7 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.06950085763121394	[874,682]	[1039,1060,1048]	1	hSpCas9	negative selection	4867174
48467036	48467058	3	-	27760321	HT29	viability after 7 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.23419457151943146	[236,184]	[373,281,308]	3	hSpCas9	negative selection	4867175
48467230	48467252	3	+	27760321	HT29	viability after 7 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.04882657716469141	[632,493]	[970,627,681]	0	hSpCas9	negative selection	4867176
48466830	48466852	3	-	27760321	HT29	viability after 25 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	0.23279144859449774	[812,634]	[918,1017,982]	2	hSpCas9	negative selection	4950635
48466922	48466944	3	+	27760321	HT29	viability after 25 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.2846421546634458	[412,321]	[456,230,337]	-3	hSpCas9	negative selection	4950636
48467015	48467037	3	-	27760321	HT29	viability after 25 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.6799065397556938	[874,682]	[1364,1285,1652]	7	hSpCas9	negative selection	4950637
48467036	48467058	3	-	27760321	HT29	viability after 25 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.128337085969511	[236,184]	[319,226,236]	1	hSpCas9	negative selection	4950638
48467230	48467252	3	+	27760321	HT29	viability after 25 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.3633151504592885	[632,493]	[767,983,724]	4	hSpCas9	negative selection	4950639
48466830	48466852	3	-	27760321	HT29	viability after 22 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	0.07386262600042959	[812,634]	[795,782,1067]	0	hSpCas9	negative selection	5034098
48466922	48466944	3	+	27760321	HT29	viability after 22 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.10600843222576277	[412,321]	[433,259,489]	-1	hSpCas9	negative selection	5034099
48467015	48467037	3	-	27760321	HT29	viability after 22 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.42746025989478653	[874,682]	[868,1314,1460]	4	hSpCas9	negative selection	5034100
48467036	48467058	3	-	27760321	HT29	viability after 22 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.5208468648967054	[236,184]	[313,378,357]	6	hSpCas9	negative selection	5034101
48467230	48467252	3	+	27760321	HT29	viability after 22 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.12897184238623982	[632,493]	[653,729,754]	1	hSpCas9	negative selection	5034102
48466830	48466852	3	-	27760321	HT29	viability after 19 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.37294517846971764	[812,634]	[975,361,615]	-3	hSpCas9	negative selection	5117561
48466922	48466944	3	+	27760321	HT29	viability after 19 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	0.07828452712563172	[412,321]	[717,370,276]	0	hSpCas9	negative selection	5117562
48467015	48467037	3	-	27760321	HT29	viability after 19 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.7790083314430585	[874,682]	[1093,1733,1704]	7	hSpCas9	negative selection	5117563
48467036	48467058	3	-	27760321	HT29	viability after 19 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.011821321819387554	[236,184]	[233,203,288]	0	hSpCas9	negative selection	5117564
48467230	48467252	3	+	27760321	HT29	viability after 19 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.32475342662251616	[632,493]	[687,981,740]	3	hSpCas9	negative selection	5117565
48466830	48466852	3	-	27760321	HT29	viability after 16 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.2445461688082582	[812,634]	[624,782,634]	-3	hSpCas9	negative selection	5201024
48466922	48466944	3	+	27760321	HT29	viability after 16 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.12006868974978936	[412,321]	[416,320,401]	-1	hSpCas9	negative selection	5201025
48467015	48467037	3	-	27760321	HT29	viability after 16 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.6063378077556045	[874,682]	[1214,1585,1161]	7	hSpCas9	negative selection	5201026
48467036	48467058	3	-	27760321	HT29	viability after 16 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	1.0943817996920617	[236,184]	[194,959,315]	9	hSpCas9	negative selection	5201027
48467230	48467252	3	+	27760321	HT29	viability after 16 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.7046505191808038	[632,493]	[1093,1008,985]	8	hSpCas9	negative selection	5201028
48466830	48466852	3	-	27760321	HT29	viability after 13 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.04264714052792151	[812,634]	[819,958,675]	0	hSpCas9	negative selection	5284487
48466922	48466944	3	+	27760321	HT29	viability after 13 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.3105134148640969	[412,321]	[397,321,312]	-4	hSpCas9	negative selection	5284488
48467015	48467037	3	-	27760321	HT29	viability after 13 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.21087005449580176	[874,682]	[981,1316,850]	2	hSpCas9	negative selection	5284489
48467036	48467058	3	-	27760321	HT29	viability after 13 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.1448378747588842	[236,184]	[278,264,267]	1	hSpCas9	negative selection	5284490
48467230	48467252	3	+	27760321	HT29	viability after 13 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.18678057357298095	[632,493]	[683,646,891]	2	hSpCas9	negative selection	5284491
48466830	48466852	3	-	27760321	HT29	viability after 10 days	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	-0.13388568780352827	[812,634]	[888,904,682]	-2	hSpCas9	negative selection	5367950
48466922	48466944	3	+	27760321	HT29	viability after 10 days	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.12015426499918712	[412,321]	[476,409,379]	-1	hSpCas9	negative selection	5367951
48467015	48467037	3	-	27760321	HT29	viability after 10 days	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.12980087975152999	[874,682]	[1175,1125,895]	1	hSpCas9	negative selection	5367952
48467036	48467058	3	-	27760321	HT29	viability after 10 days	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	0.9168246242323731	[236,184]	[538,597,360]	9	hSpCas9	negative selection	5367953
48467230	48467252	3	+	27760321	HT29	viability after 10 days	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	-0.014907562416653475	[632,493]	[526,834,729]	0	hSpCas9	negative selection	5367954
48466830	48466852	3	-	27760321	MOLM13	viability	TGTCTACCACACGCGGTGGTGG	TREX1	ENSG00000213689	0.4208948143582315	[782,812]	[959,303]	3	hSpCas9	negative selection	5451413
48466922	48466944	3	+	27760321	MOLM13	viability	AGCTGTGCTGGCAGCGCATGGG	TREX1	ENSG00000213689	-0.6542142989624282	[457,412]	[162,149]	-4	hSpCas9	negative selection	5451414
48467015	48467037	3	-	27760321	MOLM13	viability	GTCACCATTGTGTGCCACCAGG	TREX1	ENSG00000213689	0.3629839683548399	[1057,874]	[1213,258]	2	hSpCas9	negative selection	5451415
48467036	48467058	3	-	27760321	MOLM13	viability	GAGCAGGGGGAAGTCGTAGCGG	TREX1	ENSG00000213689	-1.414438345106396	[315,236]	[23,86]	-7	hSpCas9	negative selection	5451416
48467230	48467252	3	+	27760321	MOLM13	viability	CAGACTCGCACACGGCTGAGGG	TREX1	ENSG00000213689	0.8072744689033717	[697,632]	[917,433]	5	hSpCas9	negative selection	5451417
48466310	48466333	3	+	27661255	K562	viability	GTGAGTGTGGCCCCCACAATGGG	TREX1	ENSG00000213689	0.2159531222675585	[626,661]	[632,566]	7	dCas9-KRAB	negative selection	5519577
48466638	48466661	3	+	27661255	K562	viability	GCAGGTACGTACCCAACCATGGG	TREX1	ENSG00000213689	0.050947675949906346	[1681,1741]	[1519,1326]	1	dCas9-KRAB	negative selection	5519578
48466275	48466298	3	-	27661255	K562	viability	GCAGGCAGGCAGTAGTGACTCGG	TREX1	ENSG00000213689	0.15576569558533965	[914,973]	[953,741]	5	dCas9-KRAB	negative selection	5519579
48467196	48467219	3	+	27260156	BXPC3	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.3815833117339017	[455]	[529,627,648,691]	7	hSpCas9	negative selection	5577453
48466823	48466846	3	+	27260156	BXPC3	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.09233478579776744	[1063]	[906,1133,993,1153]	-2	hSpCas9	negative selection	5577454
48467229	48467252	3	-	27260156	BXPC3	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.19216824668851262	[683]	[762,748,687,1105]	4	hSpCas9	negative selection	5577455
48467114	48467137	3	+	27260156	BXPC3	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.21158581799300852	[366]	[284,331,331,385]	-5	hSpCas9	negative selection	5641701
48467222	48467245	3	+	27260156	BXPC3	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.1673271378060488	[317]	[366,294,353,494]	3	hSpCas9	negative selection	5641702
48466836	48466859	3	-	27260156	BXPC3	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.0956148320498002	[617]	[544,612,564,709]	-2	hSpCas9	negative selection	5641703
48467196	48467219	3	+	27260156	A673	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.28896252235190517	[455]	[431,492,385,479]	-6	hSpCas9	negative selection	5698704
48466823	48466846	3	+	27260156	A673	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.03710405265195882	[1063]	[1380,1268,1335,1260]	0	hSpCas9	negative selection	5698705
48467229	48467252	3	-	27260156	A673	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2291948940973586	[683]	[1072,850,983,955]	5	hSpCas9	negative selection	5698706
48467114	48467137	3	+	27260156	A673	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.09600182998260265	[366]	[463,317,437,437]	-2	hSpCas9	negative selection	5762952
48467222	48467245	3	+	27260156	A673	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.29019316538346285	[317]	[630,502,333,414]	6	hSpCas9	negative selection	5762953
48466836	48466859	3	-	27260156	A673	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.10491398075459757	[617]	[762,846,694,885]	2	hSpCas9	negative selection	5762954
48467196	48467219	3	+	27260156	A375	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.044132582788855	[455]	[569,581,514,533]	0	hSpCas9	negative selection	5819955
48466823	48466846	3	+	27260156	A375	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.35866925499129687	[1063]	[913,881,933,1112]	-5	hSpCas9	negative selection	5819956
48467229	48467252	3	-	27260156	A375	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	-0.026240194751980916	[683]	[595,1027,717,820]	0	hSpCas9	negative selection	5819957
48467114	48467137	3	+	27260156	A375	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.028231828252359148	[366]	[533,536,345,294]	0	hSpCas9	negative selection	5884203
48467222	48467245	3	+	27260156	A375	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.14446227339904932	[317]	[468,469,472,255]	2	hSpCas9	negative selection	5884204
48466836	48466859	3	-	27260156	A375	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.24423599947038047	[617]	[578,833,570,495]	-4	hSpCas9	negative selection	5884205
48467196	48467219	3	+	27260156	COLO741	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3378727873618213	[455]	[460,474,446]	-6	hSpCas9	negative selection	5941206
48466823	48466846	3	+	27260156	COLO741	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.04273300454287687	[1063]	[1504,1219,1251]	-1	hSpCas9	negative selection	5941207
48467229	48467252	3	-	27260156	COLO741	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.33180315820368744	[683]	[961,1168,1150]	7	hSpCas9	negative selection	5941208
48467114	48467137	3	+	27260156	COLO741	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.08523971129282437	[366]	[517,491,329]	-2	hSpCas9	negative selection	6005454
48467222	48467245	3	+	27260156	COLO741	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.303671585516885	[317]	[503,475,521]	6	hSpCas9	negative selection	6005455
48466836	48466859	3	-	27260156	COLO741	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.1269364570161715	[617]	[802,768,610]	-3	hSpCas9	negative selection	6005456
48467196	48467219	3	+	27260156	CAL120	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.38274885677517323	[455]	[425,382,493]	-5	hSpCas9	negative selection	6062457
48466823	48466846	3	+	27260156	CAL120	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.4876125449373301	[1063]	[1155,1078,634]	-6	hSpCas9	negative selection	6062458
48467229	48467252	3	-	27260156	CAL120	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.444641279338028	[683]	[1244,1096,1145]	6	hSpCas9	negative selection	6062459
48467114	48467137	3	+	27260156	CAL120	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.06935736290580768	[366]	[396,644,260]	-1	hSpCas9	negative selection	6126705
48467222	48467245	3	+	27260156	CAL120	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.007218823797497831	[317]	[750,259,237]	0	hSpCas9	negative selection	6126706
48466836	48466859	3	-	27260156	CAL120	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.8505090621426535	[617]	[405,430,438]	-8	hSpCas9	negative selection	6126707
48467196	48467219	3	+	27260156	CADOES1	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3760819953150789	[455]	[314,347,322,320]	-6	hSpCas9	negative selection	6183708
48466823	48466846	3	+	27260156	CADOES1	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.18268334096461136	[1063]	[794,773,1058,858]	-3	hSpCas9	negative selection	6183709
48467229	48467252	3	-	27260156	CADOES1	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.45930502458271727	[683]	[1034,808,907,740]	7	hSpCas9	negative selection	6183710
48467114	48467137	3	+	27260156	CADOES1	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.06766848234937262	[366]	[279,314,502,331]	1	hSpCas9	negative selection	6247956
48467222	48467245	3	+	27260156	CADOES1	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.33677584616771217	[317]	[266,152,166,353]	-5	hSpCas9	negative selection	6247957
48466836	48466859	3	-	27260156	CADOES1	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.2479090207065565	[617]	[395,333,440,775]	-4	hSpCas9	negative selection	6247958
48467196	48467219	3	+	27260156	EWS502	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.0454477348042784	[455]	[440,472,388,576]	-1	hSpCas9	negative selection	6304959
48466823	48466846	3	+	27260156	EWS502	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.04426759929919499	[1063]	[890,1080,1116,1319]	-1	hSpCas9	negative selection	6304960
48467229	48467252	3	-	27260156	EWS502	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.45144593464573846	[683]	[972,762,1130,1113]	7	hSpCas9	negative selection	6304961
48467114	48467137	3	+	27260156	EWS502	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.061993849232628795	[366]	[333,306,272,595]	-1	hSpCas9	negative selection	6369207
48467222	48467245	3	+	27260156	EWS502	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.20916259596010017	[317]	[262,245,589,487]	3	hSpCas9	negative selection	6369208
48466836	48466859	3	-	27260156	EWS502	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.04491260875477865	[617]	[564,646,735,593]	-1	hSpCas9	negative selection	6369209
48467196	48467219	3	+	27260156	EW8	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3482179106423385	[455]	[296,290,314,253]	-6	hSpCas9	negative selection	6426210
48466823	48466846	3	+	27260156	EW8	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.0406249597477899	[1063]	[951,924,752,944]	0	hSpCas9	negative selection	6426211
48467229	48467252	3	-	27260156	EW8	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.23294410104997132	[683]	[708,607,597,703]	4	hSpCas9	negative selection	6426212
48467114	48467137	3	+	27260156	EW8	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.1536857601149006	[366]	[293,276,337,150]	-3	hSpCas9	negative selection	6490458
48467222	48467245	3	+	27260156	EW8	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.24488983984394808	[317]	[456,238,204,352]	4	hSpCas9	negative selection	6490459
48466836	48466859	3	-	27260156	EW8	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.034726469510608926	[617]	[559,516,413,483]	0	hSpCas9	negative selection	6490460
48467196	48467219	3	+	27260156	CORL105	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.5357913757295941	[455]	[625,715,963,814]	8	hSpCas9	negative selection	6547461
48466823	48466846	3	+	27260156	CORL105	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.09778797196548727	[1063]	[1167,1018,1270,1216]	-2	hSpCas9	negative selection	6547462
48467229	48467252	3	-	27260156	CORL105	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2869268722020889	[683]	[1261,926,950,774]	5	hSpCas9	negative selection	6547463
48467114	48467137	3	+	27260156	CORL105	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.41183747227821693	[366]	[357,264,385,294]	-6	hSpCas9	negative selection	6611709
48467222	48467245	3	+	27260156	CORL105	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.32168033024539455	[317]	[441,503,543,381]	6	hSpCas9	negative selection	6611710
48466836	48466859	3	-	27260156	CORL105	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.09094629080909145	[617]	[591,580,853,715]	-2	hSpCas9	negative selection	6611711
48467196	48467219	3	+	27260156	HS294T	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.583241349143514	[455]	[245,185,254,394]	7	hSpCas9	negative selection	6668712
48466823	48466846	3	+	27260156	HS294T	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.557269795484605	[1063]	[268,278,282,288]	-7	hSpCas9	negative selection	6668713
48467229	48467252	3	-	27260156	HS294T	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.6353915789240665	[683]	[648,381,265,304]	8	hSpCas9	negative selection	6668714
48467114	48467137	3	+	27260156	HS294T	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.4400856705954314	[366]	[84,123,116,90]	-6	hSpCas9	negative selection	6732960
48467222	48467245	3	+	27260156	HS294T	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.2106138720340026	[317]	[75,177,76,262]	3	hSpCas9	negative selection	6732961
48466836	48466859	3	-	27260156	HS294T	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.18462455013848492	[617]	[237,186,194,219]	-3	hSpCas9	negative selection	6732962
48467196	48467219	3	+	27260156	HCC44	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.29738659695076464	[455]	[365,511,288,465]	-5	hSpCas9	negative selection	6789963
48466823	48466846	3	+	27260156	HCC44	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.11522115942549149	[1063]	[1549,659,1196,1145]	-2	hSpCas9	negative selection	6789964
48467229	48467252	3	-	27260156	HCC44	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.18337005890830405	[683]	[833,895,935,844]	3	hSpCas9	negative selection	6789965
48467114	48467137	3	+	27260156	HCC44	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.3289670840395777	[366]	[357,253,407,325]	-5	hSpCas9	negative selection	6854211
48467222	48467245	3	+	27260156	HCC44	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.17012556466510476	[317]	[380,341,253,290]	-3	hSpCas9	negative selection	6854212
48466836	48466859	3	-	27260156	HCC44	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.22017027130866024	[617]	[1132,665,806,696]	3	hSpCas9	negative selection	6854213
48467196	48467219	3	+	27260156	G402	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3050005321381634	[455]	[518,392,605,295]	-4	hSpCas9	negative selection	6911214
48466823	48466846	3	+	27260156	G402	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.1642775700233936	[1063]	[1783,948,1559,1534]	2	hSpCas9	negative selection	6911215
48467229	48467252	3	-	27260156	G402	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.6004327472244677	[683]	[1351,1092,1512,1108]	7	hSpCas9	negative selection	6911216
48467114	48467137	3	+	27260156	G402	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.6554826469186008	[366]	[256,292,241,337]	-7	hSpCas9	negative selection	6975462
48467222	48467245	3	+	27260156	G402	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.3258623812656162	[317]	[800,310,469,400]	4	hSpCas9	negative selection	6975463
48466836	48466859	3	-	27260156	G402	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.29975692286442773	[617]	[705,500,718,532]	-4	hSpCas9	negative selection	6975464
48467196	48467219	3	+	27260156	L33	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.5513508614458593	[455]	[592,254,449,742]	9	hSpCas9	negative selection	7032465
48466823	48466846	3	+	27260156	L33	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.1707888606104031	[1063]	[889,394,559,1035]	-4	hSpCas9	negative selection	7032466
48467229	48467252	3	-	27260156	L33	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.00849612547075751	[683]	[752,220,380,849]	0	hSpCas9	negative selection	7032467
48467114	48467137	3	+	27260156	L33	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.009166371369930648	[366]	[353,186,178,381]	0	hSpCas9	negative selection	7096713
48467222	48467245	3	+	27260156	L33	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.24039366486630986	[317]	[272,141,131,246]	-5	hSpCas9	negative selection	7096714
48466836	48466859	3	-	27260156	L33	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.35576552759324714	[617]	[477,232,256,475]	-7	hSpCas9	negative selection	7096715
48467196	48467219	3	+	27260156	K562	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.004421822345330603	[455]	[417,306,421,454]	0	hSpCas9	negative selection	7153716
48466823	48466846	3	+	27260156	K562	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.051412736128562786	[1063]	[1078,1225,1260,429]	0	hSpCas9	negative selection	7153717
48467229	48467252	3	-	27260156	K562	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.6813809363969938	[683]	[1307,890,856,868]	8	hSpCas9	negative selection	7153718
48467114	48467137	3	+	27260156	K562	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.13276208361184083	[366]	[499,355,192,385]	1	hSpCas9	negative selection	7217964
48467222	48467245	3	+	27260156	K562	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.8329104843789114	[317]	[868,440,313,420]	9	hSpCas9	negative selection	7217965
48466836	48466859	3	-	27260156	K562	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.889913810908548	[617]	[244,489,236,224]	-7	hSpCas9	negative selection	7217966
48467196	48467219	3	+	27260156	HT29	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.25894450514402245	[455]	[376,467,468,521]	-5	hSpCas9	negative selection	7274967
48466823	48466846	3	+	27260156	HT29	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.06558714585050396	[1063]	[1239,1324,1409,1410]	1	hSpCas9	negative selection	7274968
48467229	48467252	3	-	27260156	HT29	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.11918074183139582	[683]	[969,1028,874,764]	2	hSpCas9	negative selection	7274969
48467114	48467137	3	+	27260156	HT29	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.050478139366940455	[366]	[427,438,480,378]	-1	hSpCas9	negative selection	7339215
48467222	48467245	3	+	27260156	HT29	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.34830794018972755	[317]	[563,386,433,566]	6	hSpCas9	negative selection	7339216
48466836	48466859	3	-	27260156	HT29	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.08704080284004279	[617]	[631,1112,815,656]	1	hSpCas9	negative selection	7339217
48467196	48467219	3	+	27260156	MHHES1	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.13315218027196812	[455]	[491,358,456,530]	-2	hSpCas9	negative selection	7396218
48466823	48466846	3	+	27260156	MHHES1	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.06817798300772382	[1063]	[1154,1435,1349,1098]	1	hSpCas9	negative selection	7396219
48467229	48467252	3	-	27260156	MHHES1	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2254828166233932	[683]	[1091,909,1083,593]	4	hSpCas9	negative selection	7396220
48467114	48467137	3	+	27260156	MHHES1	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.001378454035411092	[366]	[425,488,424,330]	0	hSpCas9	negative selection	7460466
48467222	48467245	3	+	27260156	MHHES1	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.0166174282479451	[317]	[494,359,426,210]	0	hSpCas9	negative selection	7460467
48466836	48466859	3	-	27260156	MHHES1	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.18025075528219894	[617]	[645,568,718,528]	-3	hSpCas9	negative selection	7460468
48467196	48467219	3	+	27260156	MEWO	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3163678554999978	[455]	[434,271,338]	-6	hSpCas9	negative selection	7517469
48466823	48466846	3	+	27260156	MEWO	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.180364630951378	[1063]	[1306,1010,1100]	4	hSpCas9	negative selection	7517470
48467229	48467252	3	-	27260156	MEWO	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.08470545495336057	[683]	[864,641,564]	1	hSpCas9	negative selection	7517471
48467114	48467137	3	+	27260156	MEWO	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.15841249387093742	[366]	[399,258,281]	-3	hSpCas9	negative selection	7581717
48467222	48467245	3	+	27260156	MEWO	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	1.0065814661368198	[317]	[677,521,608]	9	hSpCas9	negative selection	7581718
48466836	48466859	3	-	27260156	MEWO	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.06320573776737137	[617]	[653,552,614]	1	hSpCas9	negative selection	7581719
48467196	48467219	3	+	27260156	LNCAPCLONEFGC	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.02131319163541562	[455]	[470,388,475,349]	0	hSpCas9	negative selection	7638720
48466823	48466846	3	+	27260156	LNCAPCLONEFGC	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.2649840652923098	[1063]	[772,799,905,744]	-4	hSpCas9	negative selection	7638721
48467229	48467252	3	-	27260156	LNCAPCLONEFGC	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.37308656896304837	[683]	[927,662,720,891]	6	hSpCas9	negative selection	7638722
48467114	48467137	3	+	27260156	LNCAPCLONEFGC	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.3513654075085228	[366]	[318,270,264,185]	-5	hSpCas9	negative selection	7702968
48467222	48467245	3	+	27260156	LNCAPCLONEFGC	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.2598971234769793	[317]	[372,314,284,398]	4	hSpCas9	negative selection	7702969
48466836	48466859	3	-	27260156	LNCAPCLONEFGC	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.3040883078172574	[617]	[440,328,642,436]	-5	hSpCas9	negative selection	7702970
48467196	48467219	3	+	27260156	PANC0327	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.4984814205104195	[455]	[738,343,614,633]	7	hSpCas9	negative selection	7759971
48466823	48466846	3	+	27260156	PANC0327	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.4784666958322912	[1063]	[662,623,669,761]	-6	hSpCas9	negative selection	7759972
48467229	48467252	3	-	27260156	PANC0327	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.7129764653905926	[683]	[1062,997,1053,873]	8	hSpCas9	negative selection	7759973
48467114	48467137	3	+	27260156	PANC0327	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.22007222600487258	[366]	[135,416,289,246]	-3	hSpCas9	negative selection	7824219
48467222	48467245	3	+	27260156	PANC0327	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.01342246472841957	[317]	[213,261,181,457]	0	hSpCas9	negative selection	7824220
48466836	48466859	3	-	27260156	PANC0327	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.18750303160292361	[617]	[424,621,290,566]	-3	hSpCas9	negative selection	7824221
48467196	48467219	3	+	27260156	NCIH2009	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.4693059589487742	[455]	[1050,826,800]	6	hSpCas9	negative selection	7881222
48466823	48466846	3	+	27260156	NCIH2009	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.3619665785608386	[1063]	[1434,1165,921]	-5	hSpCas9	negative selection	7881223
48467229	48467252	3	-	27260156	NCIH2009	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.5952539555064946	[683]	[1639,1199,1531]	7	hSpCas9	negative selection	7881224
48467114	48467137	3	+	27260156	NCIH2009	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.01702643635320067	[366]	[606,522,442]	0	hSpCas9	negative selection	7945470
48467222	48467245	3	+	27260156	NCIH2009	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.24274758239028238	[317]	[658,612,328]	3	hSpCas9	negative selection	7945471
48466836	48466859	3	-	27260156	NCIH2009	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.4957831347498748	[617]	[684,519,646]	-6	hSpCas9	negative selection	7945472
48467196	48467219	3	+	27260156	NCIH1373	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.9819451838343367	[455]	[1037,737,1132,305]	8	hSpCas9	negative selection	8002473
48466823	48466846	3	+	27260156	NCIH1373	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.2810102173872908	[1063]	[1624,672,705,278]	-3	hSpCas9	negative selection	8002474
48467229	48467252	3	-	27260156	NCIH1373	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.45518627720546767	[683]	[1678,742,791,295]	4	hSpCas9	negative selection	8002475
48467114	48467137	3	+	27260156	NCIH1373	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.11830121626880713	[366]	[434,716,237,94]	1	hSpCas9	negative selection	8066721
48467222	48467245	3	+	27260156	NCIH1373	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.1770774581460206	[317]	[527,572,115,104]	1	hSpCas9	negative selection	8066722
48466836	48466859	3	-	27260156	NCIH1373	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.7737507471951706	[617]	[630,325,275,113]	-7	hSpCas9	negative selection	8066723
48467196	48467219	3	+	27260156	PATU8902	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.9296387293800199	[455]	[1290,957,983,1712]	8	hSpCas9	negative selection	8123724
48466823	48466846	3	+	27260156	PATU8902	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.5014508294073174	[1063]	[1402,2384,1683,3144]	5	hSpCas9	negative selection	8123725
48467229	48467252	3	-	27260156	PATU8902	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	1.0688940667281928	[683]	[2364,1658,2120,1766]	9	hSpCas9	negative selection	8123726
48467114	48467137	3	+	27260156	PATU8902	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.10212144468231493	[366]	[399,620,750,342]	1	hSpCas9	negative selection	8187972
48467222	48467245	3	+	27260156	PATU8902	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.3794956876011083	[317]	[412,609,481,854]	4	hSpCas9	negative selection	8187973
48466836	48466859	3	-	27260156	PATU8902	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.2755477017128008	[617]	[1441,766,901,1082]	3	hSpCas9	negative selection	8187974
48467196	48467219	3	+	27260156	PANC1	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.5937643939559898	[455]	[569,552,881,379]	8	hSpCas9	negative selection	8244975
48466823	48466846	3	+	27260156	PANC1	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.4508667196175583	[1063]	[585,725,709,656]	-6	hSpCas9	negative selection	8244976
48467229	48467252	3	-	27260156	PANC1	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.1865339717405312	[683]	[734,797,546,615]	3	hSpCas9	negative selection	8244977
48467114	48467137	3	+	27260156	PANC1	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.3487937816373267	[366]	[291,294,172,235]	-5	hSpCas9	negative selection	8309223
48467222	48467245	3	+	27260156	PANC1	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.23467345387603045	[317]	[298,168,295,158]	-4	hSpCas9	negative selection	8309224
48466836	48466859	3	-	27260156	PANC1	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	0.2099813662003674	[617]	[616,800,585,498]	3	hSpCas9	negative selection	8309225
48467196	48467219	3	+	27260156	PANC0813	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.6174374125333779	[455]	[813,833,971,673]	8	hSpCas9	negative selection	8366226
48466823	48466846	3	+	27260156	PANC0813	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.34910563715078635	[1063]	[1057,935,797,1128]	-5	hSpCas9	negative selection	8366227
48467229	48467252	3	-	27260156	PANC0813	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.23256690269688185	[683]	[1053,991,933,811]	4	hSpCas9	negative selection	8366228
48467114	48467137	3	+	27260156	PANC0813	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.4747831322555229	[366]	[373,209,309,349]	-6	hSpCas9	negative selection	8430474
48467222	48467245	3	+	27260156	PANC0813	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	-0.027107093254247983	[317]	[517,457,280,229]	0	hSpCas9	negative selection	8430475
48466836	48466859	3	-	27260156	PANC0813	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.32288504021042336	[617]	[553,514,591,652]	-5	hSpCas9	negative selection	8430476
48467196	48467219	3	+	27260156	RDES	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.013178054990444457	[455]	[480,597,524,492]	0	hSpCas9	negative selection	8487477
48466823	48466846	3	+	27260156	RDES	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.17529441388359146	[1063]	[902,1154,1131,1154]	-3	hSpCas9	negative selection	8487478
48467229	48467252	3	-	27260156	RDES	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.4355688183483444	[683]	[926,926,1160,1287]	7	hSpCas9	negative selection	8487479
48467114	48467137	3	+	27260156	RDES	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.019266686776906072	[366]	[302,461,469,444]	0	hSpCas9	negative selection	8551725
48467222	48467245	3	+	27260156	RDES	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.29162267167251404	[317]	[460,391,554,359]	5	hSpCas9	negative selection	8551726
48466836	48466859	3	-	27260156	RDES	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.2118857652987806	[617]	[543,502,488,975]	-4	hSpCas9	negative selection	8551727
48467196	48467219	3	+	27260156	PC3	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.33354236964313805	[455]	[222,336,541,441]	-6	hSpCas9	negative selection	8608728
48466823	48466846	3	+	27260156	PC3	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.05560869272297175	[1063]	[700,987,1971,1163]	1	hSpCas9	negative selection	8608729
48467229	48467252	3	-	27260156	PC3	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.08871746333975339	[683]	[408,708,1244,818]	2	hSpCas9	negative selection	8608730
48467114	48467137	3	+	27260156	PC3	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.04286634017424423	[366]	[257,254,492,482]	-1	hSpCas9	negative selection	8672976
48467222	48467245	3	+	27260156	PC3	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.2594315766933694	[317]	[221,226,938,392]	5	hSpCas9	negative selection	8672977
48466836	48466859	3	-	27260156	PC3	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.07154479908764616	[617]	[352,695,821,605]	-2	hSpCas9	negative selection	8672978
48467196	48467219	3	+	27260156	PATU8988T	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.11047619469709076	[455]	[406,562,533,399]	2	hSpCas9	negative selection	8729979
48466823	48466846	3	+	27260156	PATU8988T	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.5103115880931257	[1063]	[696,569,683,939]	-7	hSpCas9	negative selection	8729980
48467229	48467252	3	-	27260156	PATU8988T	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.09804351724956994	[683]	[679,606,682,862]	1	hSpCas9	negative selection	8729981
48467114	48467137	3	+	27260156	PATU8988T	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.12165642747069644	[366]	[149,294,546,553]	2	hSpCas9	negative selection	8794227
48467222	48467245	3	+	27260156	PATU8988T	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.1880188644147614	[317]	[208,464,448,280]	3	hSpCas9	negative selection	8794228
48466836	48466859	3	-	27260156	PATU8988T	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.10566957226537216	[617]	[603,510,583,512]	-2	hSpCas9	negative selection	8794229
48467196	48467219	3	+	27260156	T47D	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.1650131983214937	[455]	[457,461,473,502]	-4	hSpCas9	negative selection	8851230
48466823	48466846	3	+	27260156	T47D	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.07939691327822018	[1063]	[1269,1070,1072,1292]	-2	hSpCas9	negative selection	8851231
48467229	48467252	3	-	27260156	T47D	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2845607296213227	[683]	[997,922,992,971]	6	hSpCas9	negative selection	8851232
48467114	48467137	3	+	27260156	T47D	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.08423599629007289	[366]	[366,388,440,416]	-2	hSpCas9	negative selection	8915478
48467222	48467245	3	+	27260156	T47D	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.17410426592469547	[317]	[456,404,402,407]	3	hSpCas9	negative selection	8915479
48466836	48466859	3	-	27260156	T47D	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.13482256563400224	[617]	[681,609,605,731]	-3	hSpCas9	negative selection	8915480
48467196	48467219	3	+	27260156	SU8686	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	0.5732818867492682	[455]	[699,629,650,712]	8	hSpCas9	negative selection	8972481
48466823	48466846	3	+	27260156	SU8686	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.40088803443079446	[1063]	[687,809,714,1021]	-6	hSpCas9	negative selection	8972482
48467229	48467252	3	-	27260156	SU8686	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.2351136345948387	[683]	[783,663,767,1025]	4	hSpCas9	negative selection	8972483
48467114	48467137	3	+	27260156	SU8686	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.18945113187648782	[366]	[335,256,303,394]	-3	hSpCas9	negative selection	9036729
48467222	48467245	3	+	27260156	SU8686	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.009569373040535623	[317]	[198,234,451,426]	0	hSpCas9	negative selection	9036730
48466836	48466859	3	-	27260156	SU8686	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.49943665328368547	[617]	[349,316,427,703]	-7	hSpCas9	negative selection	9036731
48467196	48467219	3	+	27260156	SKES1	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.07218154402362334	[455]	[382,521,470,361]	-1	hSpCas9	negative selection	9093732
48466823	48466846	3	+	27260156	SKES1	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.1786190583178937	[1063]	[922,868,1000,936]	-4	hSpCas9	negative selection	9093733
48467229	48467252	3	-	27260156	SKES1	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.22578896966756234	[683]	[897,985,716,638]	5	hSpCas9	negative selection	9093734
48467114	48467137	3	+	27260156	SKES1	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.08740825085225856	[366]	[436,436,267,266]	-2	hSpCas9	negative selection	9157980
48467222	48467245	3	+	27260156	SKES1	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.3958424887577661	[317]	[447,438,393,393]	7	hSpCas9	negative selection	9157981
48466836	48466859	3	-	27260156	SKES1	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.0978224557917603	[617]	[740,756,523,348]	-2	hSpCas9	negative selection	9157982
48467196	48467219	3	+	27260156	TOV112D	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.4169802623193215	[455]	[222,638,307,262]	-7	hSpCas9	negative selection	9214983
48466823	48466846	3	+	27260156	TOV112D	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	0.2832643632848453	[1063]	[1557,1301,1324,1030]	5	hSpCas9	negative selection	9214984
48467229	48467252	3	-	27260156	TOV112D	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.0635789548838076	[683]	[831,1012,659,447]	1	hSpCas9	negative selection	9214985
48467114	48467137	3	+	27260156	TOV112D	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.558677560930881	[366]	[242,391,136,259]	-8	hSpCas9	negative selection	9279231
48467222	48467245	3	+	27260156	TOV112D	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.2913303761152192	[317]	[438,680,333,185]	5	hSpCas9	negative selection	9279232
48466836	48466859	3	-	27260156	TOV112D	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.3791352252431219	[617]	[641,374,506,370]	-6	hSpCas9	negative selection	9279233
48467196	48467219	3	+	27260156	TC71	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.3827095719668248	[455]	[359,405,363,369]	-8	hSpCas9	negative selection	9336234
48466823	48466846	3	+	27260156	TC71	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.19232851498844816	[1063]	[988,1082,937,983]	-5	hSpCas9	negative selection	9336235
48467229	48467252	3	-	27260156	TC71	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.0654300028974818	[683]	[837,745,626,866]	1	hSpCas9	negative selection	9336236
48467114	48467137	3	+	27260156	TC71	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	-0.10552534488038329	[366]	[339,404,298,424]	-3	hSpCas9	negative selection	9400482
48467222	48467245	3	+	27260156	TC71	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.12803926929766407	[317]	[347,356,334,456]	3	hSpCas9	negative selection	9400483
48466836	48466859	3	-	27260156	TC71	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.0673639075558975	[617]	[682,693,505,649]	-2	hSpCas9	negative selection	9400484
48467196	48467219	3	+	27260156	TC32	viability	AGCATCTACACTCGCCTGTATGG	TREX1	ENSG00000213689	-0.5584273890379623	[455]	[305,181,368,345]	-8	hSpCas9	negative selection	9457485
48466823	48466846	3	+	27260156	TC32	viability	AGTTCCTCCACCACCGCGTGTGG	TREX1	ENSG00000213689	-0.3453785310436033	[1063]	[790,608,834,948]	-6	hSpCas9	negative selection	9457486
48467229	48467252	3	-	27260156	TC32	viability	CCCTCAGCCGTGTGCGAGTCTGG	TREX1	ENSG00000213689	0.4559720404993213	[683]	[620,968,1129,786]	7	hSpCas9	negative selection	9457487
48467114	48467137	3	+	27260156	TC32	viability	GGATAGCATCACTGCGCTGAAGG	TREX1	ENSG00000213689	0.19225460907769007	[366]	[480,221,506,417]	3	hSpCas9	negative selection	9521733
48467222	48467245	3	+	27260156	TC32	viability	GTCCCCTCCAGACTCGCACACGG	TREX1	ENSG00000213689	0.051092704067454475	[317]	[303,191,429,363]	0	hSpCas9	negative selection	9521734
48466836	48466859	3	-	27260156	TC32	viability	GAGAGCTTGTCTACCACACGCGG	TREX1	ENSG00000213689	-0.2516908147316647	[617]	[348,541,631,413]	-4	hSpCas9	negative selection	9521735
48466576	48466599	3	-	27869803	HPAFII	viability after 27 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.45702798750470774	[262]	[151,57,NaN]	-3	hSpCas9	negative selection	9585157
48466577	48466600	3	-	27869803	HPAFII	viability after 27 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.06122133901943261	[244]	[117,127,NaN]	0	hSpCas9	negative selection	9585158
48467050	48467073	3	-	27869803	HPAFII	viability after 27 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.35462136219604795	[196]	[74,85,NaN]	-3	hSpCas9	negative selection	9585159
48467414	48467437	3	-	27869803	HPAFII	viability after 27 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.037876822764402	[118]	[140,117,NaN]	8	hSpCas9	negative selection	9585160
48467539	48467562	3	-	27869803	HPAFII	viability after 27 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.018701305673731072	[98]	[49,54,NaN]	0	hSpCas9	negative selection	9585161
48466576	48466599	3	-	27869803	HPAFII	viability after 15 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.05414971753423292	[262]	[446,197,NaN]	0	hSpCas9	negative selection	9667606
48466577	48466600	3	-	27869803	HPAFII	viability after 15 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.8024043540342091	[244]	[584,380,NaN]	8	hSpCas9	negative selection	9667607
48467050	48467073	3	-	27869803	HPAFII	viability after 15 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.08767578574621243	[196]	[269,196,NaN]	1	hSpCas9	negative selection	9667608
48467414	48467437	3	-	27869803	HPAFII	viability after 15 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	0.7181576568024871	[118]	[321,140,NaN]	7	hSpCas9	negative selection	9667609
48467539	48467562	3	-	27869803	HPAFII	viability after 15 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	-0.11078749613766004	[98]	[100,96,NaN]	-1	hSpCas9	negative selection	9667610
48466576	48466599	3	-	27869803	ASPC1	viability after 36 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	0.04305774718779589	[643]	[206,371,134]	0	hSpCas9	negative selection	9750055
48466577	48466600	3	-	27869803	ASPC1	viability after 36 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.9079723725691786	[671]	[179,167,50]	-7	hSpCas9	negative selection	9750056
48467050	48467073	3	-	27869803	ASPC1	viability after 36 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	-0.6183158270968874	[560]	[8,311,62]	-6	hSpCas9	negative selection	9750057
48467414	48467437	3	-	27869803	ASPC1	viability after 36 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.0494321824205333	[353]	[366,86,308]	8	hSpCas9	negative selection	9750058
48467539	48467562	3	-	27869803	ASPC1	viability after 36 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.7328663092862806	[250]	[321,9,127]	7	hSpCas9	negative selection	9750059
48466576	48466599	3	-	27869803	PATU8988S	viability after 35 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.14112738766100175	[507]	[198,171,NaN]	-1	hSpCas9	negative selection	9832504
48466577	48466600	3	-	27869803	PATU8988S	viability after 35 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.8350905761483597	[541]	[355,422,NaN]	8	hSpCas9	negative selection	9832505
48467050	48467073	3	-	27869803	PATU8988S	viability after 35 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.6444440941413209	[670]	[391,452,NaN]	7	hSpCas9	negative selection	9832506
48467414	48467437	3	-	27869803	PATU8988S	viability after 35 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	-0.1374344451981936	[328]	[104,135,NaN]	-1	hSpCas9	negative selection	9832507
48467539	48467562	3	-	27869803	PATU8988S	viability after 35 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.8018087197162328	[194]	[97,175,NaN]	8	hSpCas9	negative selection	9832508
48466576	48466599	3	-	27869803	PATU8988S	viability after 31 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.014033176347233348	[507]	[204,194,NaN]	0	hSpCas9	negative selection	9914953
48466577	48466600	3	-	27869803	PATU8988S	viability after 31 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.6510799363463785	[541]	[246,456,NaN]	7	hSpCas9	negative selection	9914954
48467050	48467073	3	-	27869803	PATU8988S	viability after 31 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.4739964812678513	[670]	[291,472,NaN]	6	hSpCas9	negative selection	9914955
48467414	48467437	3	-	27869803	PATU8988S	viability after 31 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	-0.12673337353585223	[328]	[91,155,NaN]	-1	hSpCas9	negative selection	9914956
48467539	48467562	3	-	27869803	PATU8988S	viability after 31 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.7290448192050303	[194]	[138,115,NaN]	8	hSpCas9	negative selection	9914957
48466576	48466599	3	-	27869803	HPAFII	viability after 35 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-1.0953864614192403	[262]	[98,20,NaN]	-6	hSpCas9	negative selection	9997402
48466577	48466600	3	-	27869803	HPAFII	viability after 35 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	0.33432124638768757	[244]	[201,104,NaN]	2	hSpCas9	negative selection	9997403
48467050	48467073	3	-	27869803	HPAFII	viability after 35 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.010662813293038698	[196]	[99,100,NaN]	0	hSpCas9	negative selection	9997404
48467414	48467437	3	-	27869803	HPAFII	viability after 35 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.028440211222848	[118]	[128,115,NaN]	7	hSpCas9	negative selection	9997405
48467539	48467562	3	-	27869803	HPAFII	viability after 35 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.10465962592801503	[98]	[67,37,NaN]	0	hSpCas9	negative selection	9997406
48466576	48466599	3	-	27869803	HPAFII	viability after 31 days	GCCCAGTGTTAAGATCCGAAGGG	TREX1	ENSG00000213689	-0.35647784839686836	[262]	[143,83,NaN]	-2	hSpCas9	negative selection	10079851
48466577	48466600	3	-	27869803	HPAFII	viability after 31 days	TGCCCAGTGTTAAGATCCGAAGG	TREX1	ENSG00000213689	-0.15373180631030062	[244]	[136,108,NaN]	-1	hSpCas9	negative selection	10079852
48467050	48467073	3	-	27869803	HPAFII	viability after 31 days	AGCCAGCTCTGCTTGGAGCAGGG	TREX1	ENSG00000213689	0.4514973940575323	[196]	[132,170,NaN]	3	hSpCas9	negative selection	10079853
48467414	48467437	3	-	27869803	HPAFII	viability after 31 days	TAGTGTTCCTGGTTGTGGCCAGG	TREX1	ENSG00000213689	1.3302573379627314	[118]	[210,120,NaN]	8	hSpCas9	negative selection	10079854
48467539	48467562	3	-	27869803	HPAFII	viability after 31 days	GGCTACTGCCAAGGTCAGGATGG	TREX1	ENSG00000213689	0.41416405864745875	[98]	[85,60,NaN]	3	hSpCas9	negative selection	10079855
48467523	48467546	3	-	28162770	P31FUJ	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.3251932487065081	[107]	[158]	3	hSpCas9	negative selection	10256483
48466766	48466789	3	+	28162770	P31FUJ	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.14658759379244113	[378]	[492]	1	hSpCas9	negative selection	10256484
48466812	48466835	3	-	28162770	P31FUJ	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.180334784520243	[296]	[76]	-8	hSpCas9	negative selection	10256485
48466833	48466856	3	-	28162770	P31FUJ	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.19604109438949568	[77]	[104]	2	hSpCas9	negative selection	10256486
48467388	48467411	3	-	28162770	P31FUJ	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.23330252535424245	[450]	[622]	2	hSpCas9	negative selection	10256487
48467086	48467109	3	-	28162770	P31FUJ	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.21912726751730208	[209]	[211]	-2	hSpCas9	negative selection	10256488
48467104	48467127	3	-	28162770	P31FUJ	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.0864763120590345	[326]	[407]	0	hSpCas9	negative selection	10256489
48467284	48467307	3	+	28162770	P31FUJ	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.044099995941438166	[228]	[260]	0	hSpCas9	negative selection	10256490
48467404	48467427	3	-	28162770	P31FUJ	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.07721912378880968	[291]	[361]	0	hSpCas9	negative selection	10256491
48466736	48466759	3	-	28162770	P31FUJ	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.32636464540587373	[636]	[596]	-3	hSpCas9	negative selection	10256492
48467523	48467546	3	-	28162770	TF1	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10425849
48466766	48466789	3	+	28162770	TF1	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	NaN	[NaN]	[259]	1	hSpCas9	negative selection	10425850
48466812	48466835	3	-	28162770	TF1	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10425851
48466833	48466856	3	-	28162770	TF1	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10425852
48467388	48467411	3	-	28162770	TF1	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10425853
48467086	48467109	3	-	28162770	TF1	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10425854
48467104	48467127	3	-	28162770	TF1	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10425855
48467284	48467307	3	+	28162770	TF1	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10425856
48467404	48467427	3	-	28162770	TF1	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10425857
48466736	48466759	3	-	28162770	TF1	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	NaN	[NaN]	[670]	1	hSpCas9	negative selection	10425858
48467523	48467546	3	-	28162770	SKM1	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.2999888263566051	[33]	[73]	3	hSpCas9	negative selection	10595215
48466766	48466789	3	+	28162770	SKM1	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.09827110950726015	[92]	[175]	0	hSpCas9	negative selection	10595216
48466812	48466835	3	-	28162770	SKM1	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.030109893352206	[66]	[28]	-8	hSpCas9	negative selection	10595217
48466833	48466856	3	-	28162770	SKM1	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-1.342833861323446	[32]	[22]	-7	hSpCas9	negative selection	10595218
48467388	48467411	3	-	28162770	SKM1	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.16151017918942534	[131]	[260]	1	hSpCas9	negative selection	10595219
48467086	48467109	3	-	28162770	SKM1	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.09184165822827989	[68]	[129]	0	hSpCas9	negative selection	10595220
48467104	48467127	3	-	28162770	SKM1	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.5381738662223201	[66]	[171]	5	hSpCas9	negative selection	10595221
48467284	48467307	3	+	28162770	SKM1	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.5875364443849825	[50]	[59]	-5	hSpCas9	negative selection	10595222
48467404	48467427	3	-	28162770	SKM1	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.22724182099784346	[71]	[148]	2	hSpCas9	negative selection	10595223
48466736	48466759	3	-	28162770	SKM1	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.3573334310185612	[149]	[206]	-3	hSpCas9	negative selection	10595224
48467523	48467546	3	-	28162770	SKM1	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.2999888263566051	[33]	[73]	3	hSpCas9	negative selection	10764581
48466766	48466789	3	+	28162770	SKM1	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.09827110950726015	[92]	[175]	0	hSpCas9	negative selection	10764582
48466812	48466835	3	-	28162770	SKM1	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.030109893352206	[66]	[28]	-8	hSpCas9	negative selection	10764583
48466833	48466856	3	-	28162770	SKM1	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-1.342833861323446	[32]	[22]	-7	hSpCas9	negative selection	10764584
48467388	48467411	3	-	28162770	SKM1	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.16151017918942534	[131]	[260]	1	hSpCas9	negative selection	10764585
48467086	48467109	3	-	28162770	SKM1	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.09184165822827989	[68]	[129]	0	hSpCas9	negative selection	10764586
48467104	48467127	3	-	28162770	SKM1	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.5381738662223201	[66]	[171]	5	hSpCas9	negative selection	10764587
48467284	48467307	3	+	28162770	SKM1	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.5875364443849825	[50]	[59]	-5	hSpCas9	negative selection	10764588
48467404	48467427	3	-	28162770	SKM1	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.22724182099784346	[71]	[148]	2	hSpCas9	negative selection	10764589
48466736	48466759	3	-	28162770	SKM1	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.3573334310185612	[149]	[206]	-3	hSpCas9	negative selection	10764590
48467523	48467546	3	-	28162770	PL21	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.384822886231836	[113]	[37]	-3	hSpCas9	negative selection	10933947
48466766	48466789	3	+	28162770	PL21	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.06183046444936369	[270]	[112]	0	hSpCas9	negative selection	10933948
48466812	48466835	3	-	28162770	PL21	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-0.4639930996654437	[205]	[64]	-3	hSpCas9	negative selection	10933949
48466833	48466856	3	-	28162770	PL21	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-0.5822689504380532	[85]	[24]	-4	hSpCas9	negative selection	10933950
48467388	48467411	3	-	28162770	PL21	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.38901490967299246	[478]	[272]	3	hSpCas9	negative selection	10933951
48467086	48467109	3	-	28162770	PL21	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.26414140380937273	[297]	[107]	-2	hSpCas9	negative selection	10933952
48467104	48467127	3	-	28162770	PL21	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.9881639162678466	[236]	[51]	-6	hSpCas9	negative selection	10933953
48467284	48467307	3	+	28162770	PL21	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.8126844258682635	[225]	[55]	-5	hSpCas9	negative selection	10933954
48467404	48467427	3	-	28162770	PL21	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-1.378128233657828	[214]	[35]	-7	hSpCas9	negative selection	10933955
48466736	48466759	3	-	28162770	PL21	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	0.49370281812332073	[451]	[276]	4	hSpCas9	negative selection	10933956
48467523	48467546	3	-	28162770	P31FUJ	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.3251932487065081	[107]	[158]	3	hSpCas9	negative selection	11103313
48466766	48466789	3	+	28162770	P31FUJ	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.14658759379244113	[378]	[492]	1	hSpCas9	negative selection	11103314
48466812	48466835	3	-	28162770	P31FUJ	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.180334784520243	[296]	[76]	-8	hSpCas9	negative selection	11103315
48466833	48466856	3	-	28162770	P31FUJ	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.19604109438949568	[77]	[104]	2	hSpCas9	negative selection	11103316
48467388	48467411	3	-	28162770	P31FUJ	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.23330252535424245	[450]	[622]	2	hSpCas9	negative selection	11103317
48467086	48467109	3	-	28162770	P31FUJ	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.21912726751730208	[209]	[211]	-2	hSpCas9	negative selection	11103318
48467104	48467127	3	-	28162770	P31FUJ	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.0864763120590345	[326]	[407]	0	hSpCas9	negative selection	11103319
48467284	48467307	3	+	28162770	P31FUJ	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.044099995941438166	[228]	[260]	0	hSpCas9	negative selection	11103320
48467404	48467427	3	-	28162770	P31FUJ	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.07721912378880968	[291]	[361]	0	hSpCas9	negative selection	11103321
48466736	48466759	3	-	28162770	P31FUJ	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.32636464540587373	[636]	[596]	-3	hSpCas9	negative selection	11103322
48467523	48467546	3	-	28162770	OCIAML5	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	0.8108984418584324	[53]	[170]	7	hSpCas9	negative selection	11272679
48466766	48466789	3	+	28162770	OCIAML5	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	1.0651448304222417	[129]	[490]	8	hSpCas9	negative selection	11272680
48466812	48466835	3	-	28162770	OCIAML5	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.822319227469945	[95]	[48]	-7	hSpCas9	negative selection	11272681
48466833	48466856	3	-	28162770	OCIAML5	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-0.4597491480852367	[79]	[104]	-3	hSpCas9	negative selection	11272682
48467388	48467411	3	-	28162770	OCIAML5	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.28270198516469924	[239]	[526]	2	hSpCas9	negative selection	11272683
48467086	48467109	3	-	28162770	OCIAML5	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-1.4150027652551542	[129]	[87]	-7	hSpCas9	negative selection	11272684
48467104	48467127	3	-	28162770	OCIAML5	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.041018225219490945	[223]	[415]	0	hSpCas9	negative selection	11272685
48467284	48467307	3	+	28162770	OCIAML5	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.35403970691412157	[113]	[160]	-3	hSpCas9	negative selection	11272686
48467404	48467427	3	-	28162770	OCIAML5	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.5890321650302032	[144]	[173]	-4	hSpCas9	negative selection	11272687
48466736	48466759	3	-	28162770	OCIAML5	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.9672363412841782	[390]	[360]	-6	hSpCas9	negative selection	11272688
48467523	48467546	3	-	28162770	EOL1	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.20392678637827466	[222]	[101]	-1	hSpCas9	negative selection	11442045
48466766	48466789	3	+	28162770	EOL1	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.8258043762105818	[396]	[117]	-5	hSpCas9	negative selection	11442046
48466812	48466835	3	-	28162770	EOL1	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	0.4662841694921569	[462]	[336]	4	hSpCas9	negative selection	11442047
48466833	48466856	3	-	28162770	EOL1	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-2.5779525689586484	[203]	[17]	-9	hSpCas9	negative selection	11442048
48467388	48467411	3	-	28162770	EOL1	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.3975492521787032	[682]	[473]	3	hSpCas9	negative selection	11442049
48467086	48467109	3	-	28162770	EOL1	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.509653732244534	[580]	[214]	-4	hSpCas9	negative selection	11442050
48467104	48467127	3	-	28162770	EOL1	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.4677696512082256	[314]	[119]	-3	hSpCas9	negative selection	11442051
48467284	48467307	3	+	28162770	EOL1	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-1.67061049625651	[283]	[46]	-8	hSpCas9	negative selection	11442052
48467404	48467427	3	-	28162770	EOL1	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.814220065229657	[266]	[79]	-5	hSpCas9	negative selection	11442053
48466736	48466759	3	-	28162770	EOL1	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.37196790414381353	[618]	[251]	-3	hSpCas9	negative selection	11442054
48467523	48467546	3	-	28162770	MOLM13	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.035279028012930036	[179]	[126]	0	hSpCas9	negative selection	11611411
48466766	48466789	3	+	28162770	MOLM13	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-1.065358082632422	[410]	[141]	-5	hSpCas9	negative selection	11611412
48466812	48466835	3	-	28162770	MOLM13	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-2.738962188896091	[276]	[29]	-8	hSpCas9	negative selection	11611413
48466833	48466856	3	-	28162770	MOLM13	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	1.1410790652774703	[147]	[235]	8	hSpCas9	negative selection	11611414
48467388	48467411	3	-	28162770	MOLM13	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	1.3443470525541739	[724]	[1330]	8	hSpCas9	negative selection	11611415
48467086	48467109	3	-	28162770	MOLM13	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.13909942550657617	[395]	[259]	-1	hSpCas9	negative selection	11611416
48467104	48467127	3	-	28162770	MOLM13	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.06290554692965789	[428]	[323]	0	hSpCas9	negative selection	11611417
48467284	48467307	3	+	28162770	MOLM13	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-3.0764311346792312	[244]	[20]	-8	hSpCas9	negative selection	11611418
48467404	48467427	3	-	28162770	MOLM13	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.058245141035953456	[266]	[200]	0	hSpCas9	negative selection	11611419
48466736	48466759	3	-	28162770	MOLM13	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-1.0716301484154103	[624]	[214]	-5	hSpCas9	negative selection	11611420
48467523	48467546	3	-	28162770	HEL	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.9625436531003951	[142]	[46]	-5	hSpCas9	negative selection	11780777
48466766	48466789	3	+	28162770	HEL	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.77872493643792	[374]	[139]	-5	hSpCas9	negative selection	11780778
48466812	48466835	3	-	28162770	HEL	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.2249009475256678	[280]	[76]	-6	hSpCas9	negative selection	11780779
48466833	48466856	3	-	28162770	HEL	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.07526375800804208	[122]	[82]	0	hSpCas9	negative selection	11780780
48467388	48467411	3	-	28162770	HEL	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.5707752364804244	[595]	[566]	5	hSpCas9	negative selection	11780781
48467086	48467109	3	-	28162770	HEL	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.15120319524746972	[425]	[302]	1	hSpCas9	negative selection	11780782
48467104	48467127	3	-	28162770	HEL	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.28140235255475926	[333]	[259]	2	hSpCas9	negative selection	11780783
48467284	48467307	3	+	28162770	HEL	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.954660771959022	[232]	[76]	-5	hSpCas9	negative selection	11780784
48467404	48467427	3	-	28162770	HEL	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.2504214092215966	[251]	[191]	2	hSpCas9	negative selection	11780785
48466736	48466759	3	-	28162770	HEL	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	0.28298376822270255	[511]	[398]	2	hSpCas9	negative selection	11780786
48467523	48467546	3	-	28162770	MV411	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.039085207973388325	[160]	[131]	0	hSpCas9	negative selection	11950143
48466766	48466789	3	+	28162770	MV411	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.07055978869869606	[285]	[252]	0	hSpCas9	negative selection	11950144
48466812	48466835	3	-	28162770	MV411	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.3598927629668354	[194]	[63]	-7	hSpCas9	negative selection	11950145
48466833	48466856	3	-	28162770	MV411	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	0.012972297145752432	[79]	[67]	0	hSpCas9	negative selection	11950146
48467388	48467411	3	-	28162770	MV411	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.22096533942158425	[439]	[431]	2	hSpCas9	negative selection	11950147
48467086	48467109	3	-	28162770	MV411	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.26521074512249077	[320]	[224]	-2	hSpCas9	negative selection	11950148
48467104	48467127	3	-	28162770	MV411	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.5487061751040446	[210]	[259]	5	hSpCas9	negative selection	11950149
48467284	48467307	3	+	28162770	MV411	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.7439493189125166	[166]	[83]	-5	hSpCas9	negative selection	11950150
48467404	48467427	3	-	28162770	MV411	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.07610159401057254	[223]	[178]	0	hSpCas9	negative selection	11950151
48466736	48466759	3	-	28162770	MV411	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.17227643570554185	[411]	[307]	-1	hSpCas9	negative selection	11950152
48467523	48467546	3	-	28162770	MONOMAC1	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.2313883518503308	[84]	[82]	-2	hSpCas9	negative selection	12119509
48466766	48466789	3	+	28162770	MONOMAC1	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.06579231378130107	[167]	[183]	0	hSpCas9	negative selection	12119510
48466812	48466835	3	-	28162770	MONOMAC1	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-0.4653269783448429	[164]	[136]	-4	hSpCas9	negative selection	12119511
48466833	48466856	3	-	28162770	MONOMAC1	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-0.07365443155427132	[55]	[60]	0	hSpCas9	negative selection	12119512
48467388	48467411	3	-	28162770	MONOMAC1	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.6977809162483897	[255]	[475]	6	hSpCas9	negative selection	12119513
48467086	48467109	3	-	28162770	MONOMAC1	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	0.5279561054405766	[120]	[199]	5	hSpCas9	negative selection	12119514
48467104	48467127	3	-	28162770	MONOMAC1	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	0.5399287471066524	[179]	[299]	5	hSpCas9	negative selection	12119515
48467284	48467307	3	+	28162770	MONOMAC1	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.017713147614991653	[203]	[230]	0	hSpCas9	negative selection	12119516
48467404	48467427	3	-	28162770	MONOMAC1	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.40530773188983904	[109]	[166]	4	hSpCas9	negative selection	12119517
48466736	48466759	3	-	28162770	MONOMAC1	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.15894367588747893	[298]	[306]	-1	hSpCas9	negative selection	12119518
48467523	48467546	3	-	28162770	OCIAML2	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.3153515997642502	[21]	[97]	-3	hSpCas9	negative selection	12288875
48466766	48466789	3	+	28162770	OCIAML2	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	0.0900851292323176	[49]	[294]	0	hSpCas9	negative selection	12288876
48466812	48466835	3	-	28162770	OCIAML2	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-1.4706298252421612	[36]	[73]	-7	hSpCas9	negative selection	12288877
48466833	48466856	3	-	28162770	OCIAML2	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-0.2742326124386578	[11]	[54]	-2	hSpCas9	negative selection	12288878
48467388	48467411	3	-	28162770	OCIAML2	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.28651365086167546	[70]	[479]	2	hSpCas9	negative selection	12288879
48467086	48467109	3	-	28162770	OCIAML2	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.46357506770821066	[50]	[204]	-4	hSpCas9	negative selection	12288880
48467104	48467127	3	-	28162770	OCIAML2	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.8223413891521758	[51]	[162]	-5	hSpCas9	negative selection	12288881
48467284	48467307	3	+	28162770	OCIAML2	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-1.0895396578866552	[42]	[111]	-6	hSpCas9	negative selection	12288882
48467404	48467427	3	-	28162770	OCIAML2	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	-0.18905946797093992	[28]	[140]	-1	hSpCas9	negative selection	12288883
48466736	48466759	3	-	28162770	OCIAML2	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.6096062383909717	[97]	[355]	-4	hSpCas9	negative selection	12288884
48467523	48467546	3	-	28162770	OCIAML3	viability	AGGATGGCCAGCAGACCCAGTGG	TREX1	ENSG00000213689	-0.08210860179273027	[26]	[76]	0	hSpCas9	negative selection	12458241
48466766	48466789	3	+	28162770	OCIAML3	viability	GGCTGTCCACAGATGTGCCCTGG	TREX1	ENSG00000213689	-0.3685875262901471	[67]	[158]	-3	hSpCas9	negative selection	12458242
48466812	48466835	3	-	28162770	OCIAML3	viability	GGTGGAGGAACTGTGGGAGGTGG	TREX1	ENSG00000213689	-0.786652718266559	[59]	[104]	-5	hSpCas9	negative selection	12458243
48466833	48466856	3	-	28162770	OCIAML3	viability	AGCTTGTCTACCACACGCGGTGG	TREX1	ENSG00000213689	-0.009045139603007124	[20]	[62]	0	hSpCas9	negative selection	12458244
48467388	48467411	3	-	28162770	OCIAML3	viability	GCAGTGGTTGTGACAGCAGATGG	TREX1	ENSG00000213689	0.1756465725482177	[143]	[490]	1	hSpCas9	negative selection	12458245
48467086	48467109	3	-	28162770	OCIAML3	viability	GAAGGCACCATCCAGAGCACTGG	TREX1	ENSG00000213689	-0.0714416767408741	[62]	[180]	0	hSpCas9	negative selection	12458246
48467104	48467127	3	-	28162770	OCIAML3	viability	AGTGATGCTATCCACACAGAAGG	TREX1	ENSG00000213689	-0.4785304229042273	[83]	[181]	-4	hSpCas9	negative selection	12458247
48467284	48467307	3	+	28162770	OCIAML3	viability	GGAGACCACAGGCCCTGCTGCGG	TREX1	ENSG00000213689	-0.5334660983891124	[69]	[145]	-4	hSpCas9	negative selection	12458248
48467404	48467427	3	-	28162770	OCIAML3	viability	GGTTGTGGCCAGGTGTGCAGTGG	TREX1	ENSG00000213689	0.21906093292783474	[71]	[252]	2	hSpCas9	negative selection	12458249
48466736	48466759	3	-	28162770	OCIAML3	viability	ACAGCTCCGTGACCTTGGGCTGG	TREX1	ENSG00000213689	-0.03601218720327637	[125]	[370]	0	hSpCas9	negative selection	12458250