Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7248
• Symbol: TSC1
• Description: TSC complex subunit 1

DataSource: http://genomecrispr.dkfz.de/#!/results/TSC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
132903699	132903722	9	+	26472758	Jiyoye	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-0.537115185907839	[253]	[131]	-4	hSpCas9	negative selection	173550
132903650	132903673	9	-	26472758	Jiyoye	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	1.500284785897355	[29]	[63]	8	hSpCas9	negative selection	173551
132921920	132921943	9	+	26472758	Jiyoye	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	0.9326368704783676	[65]	[94]	6	hSpCas9	negative selection	173552
132911025	132911048	9	+	26472758	Jiyoye	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	0.44706810862938606	[213]	[219]	3	hSpCas9	negative selection	173553
132910653	132910676	9	+	26472758	Jiyoye	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	173554
132906814	132906837	9	-	26472758	Jiyoye	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	1.170317598231153	[141]	[240]	7	hSpCas9	negative selection	173555
132906076	132906099	9	-	26472758	Jiyoye	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.01231576416466007	[141]	[107]	0	hSpCas9	negative selection	173556
132905988	132906011	9	+	26472758	Jiyoye	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	1.2145303035634774	[99]	[174]	7	hSpCas9	negative selection	173557
132905628	132905651	9	+	26472758	Jiyoye	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-0.5577421593386815	[649]	[332]	-4	hSpCas9	negative selection	173558
132903790	132903813	9	+	26472758	Jiyoye	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.10739779132388488	[169]	[118]	-1	hSpCas9	negative selection	173559
132903699	132903722	9	+	26472758	KBM7	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	2.173449669642472	[519,304]	[1273,481]	9	hSpCas9	negative selection	364668
132903650	132903673	9	-	26472758	KBM7	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	2.512314578561537	[173,173]	[911,72]	9	hSpCas9	negative selection	364669
132921920	132921943	9	+	26472758	KBM7	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	1.1469537422086011	[410,191]	[505,122]	9	hSpCas9	negative selection	364670
132911025	132911048	9	+	26472758	KBM7	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	1.4678023949719676	[762,838]	[1790,390]	9	hSpCas9	negative selection	364671
132910653	132910676	9	+	26472758	KBM7	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	0.266195911673361	[80,32]	[30,30]	2	hSpCas9	negative selection	364672
132906814	132906837	9	-	26472758	KBM7	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	1.0637664442855508	[886,699]	[1183,407]	9	hSpCas9	negative selection	364673
132906076	132906099	9	-	26472758	KBM7	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	1.3147676301090618	[675,397]	[934,327]	9	hSpCas9	negative selection	364674
132905988	132906011	9	+	26472758	KBM7	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	1.8971468816305608	[740,760]	[2211,528]	9	hSpCas9	negative selection	364675
132905628	132905651	9	+	26472758	KBM7	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	2.1871136627183425	[1929,1423]	[5962,1397]	9	hSpCas9	negative selection	364676
132903790	132903813	9	+	26472758	KBM7	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	1.6851686027579507	[972,836]	[2666,199]	9	hSpCas9	negative selection	364677
132903699	132903722	9	+	26472758	Raji	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-0.3484990161826269	[202]	[36]	-3	hSpCas9	negative selection	555786
132903650	132903673	9	-	26472758	Raji	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-0.7505974597539726	[57]	[7]	-5	hSpCas9	negative selection	555787
132921920	132921943	9	+	26472758	Raji	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-1.1611053005523022	[105]	[10]	-7	hSpCas9	negative selection	555788
132911025	132911048	9	+	26472758	Raji	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.7890716075686082	[550]	[73]	-6	hSpCas9	negative selection	555789
132910653	132910676	9	+	26472758	Raji	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-3.699971386684005	[55]	[0]	-9	hSpCas9	negative selection	555790
132906814	132906837	9	-	26472758	Raji	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.14428311818512873	[385]	[98]	1	hSpCas9	negative selection	555791
132906076	132906099	9	-	26472758	Raji	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-1.2251918037132714	[271]	[26]	-7	hSpCas9	negative selection	555792
132905988	132906011	9	+	26472758	Raji	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-1.04673960994582	[453]	[50]	-6	hSpCas9	negative selection	555793
132905628	132905651	9	+	26472758	Raji	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-1.1754525882151863	[982]	[100]	-7	hSpCas9	negative selection	555794
132903790	132903813	9	+	26472758	Raji	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.7702049243867203	[462]	[62]	-5	hSpCas9	negative selection	555795
132903699	132903722	9	+	26472758	K562	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-0.24844948307272408	[310]	[220]	-2	hSpCas9	negative selection	746904
132903650	132903673	9	-	26472758	K562	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	0.054087515562297295	[88]	[77]	0	hSpCas9	negative selection	746905
132921920	132921943	9	+	26472758	K562	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.028957622388805948	[167]	[138]	0	hSpCas9	negative selection	746906
132911025	132911048	9	+	26472758	K562	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.09801075305752305	[690]	[544]	0	hSpCas9	negative selection	746907
132910653	132910676	9	+	26472758	K562	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-4.709777582720427	[30]	[0]	-9	hSpCas9	negative selection	746908
132906814	132906837	9	-	26472758	K562	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.5284868333724375	[748]	[911]	4	hSpCas9	negative selection	746909
132906076	132906099	9	-	26472758	K562	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.19615386371953442	[322]	[237]	-1	hSpCas9	negative selection	746910
132905988	132906011	9	+	26472758	K562	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.3344683323088702	[589]	[627]	2	hSpCas9	negative selection	746911
132905628	132905651	9	+	26472758	K562	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.38450849956799615	[1519]	[1674]	3	hSpCas9	negative selection	746912
132903790	132903813	9	+	26472758	K562	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.1894925171628532	[695]	[669]	1	hSpCas9	negative selection	746913
132910617	132910640	9	+	26627737	DLD1	viability	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	1.1959524241225616	[111]	[55,106,78]	9	hSpCas9	negative selection	841821
132911522	132911545	9	+	26627737	DLD1	viability	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.17967450268094876	[765]	[463,187,172]	1	hSpCas9	negative selection	841822
132921373	132921396	9	-	26627737	DLD1	viability	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.2336099928309613	[395]	[159,182,101]	2	hSpCas9	negative selection	841823
132921926	132921949	9	+	26627737	DLD1	viability	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.32589726951761255	[999]	[362,492,332]	3	hSpCas9	negative selection	841824
132923461	132923484	9	-	26627737	DLD1	viability	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.6608690836586671	[912]	[350,559,447]	6	hSpCas9	negative selection	841825
132925661	132925684	9	+	26627737	DLD1	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.16745160827204364	[1370]	[477,495,471]	1	hSpCas9	negative selection	841826
132910617	132910640	9	+	26627737	GBM cells	viability after 5 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.20296573913352822	[87]	[51,29]	-3	hSpCas9	negative selection	924136
132911522	132911545	9	+	26627737	GBM cells	viability after 5 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.5748625925456305	[517]	[184,187]	-7	hSpCas9	negative selection	924137
132921373	132921396	9	-	26627737	GBM cells	viability after 5 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.02851972666008018	[382]	[200,217]	0	hSpCas9	negative selection	924138
132921926	132921949	9	+	26627737	GBM cells	viability after 5 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.0455237095605171	[401]	[219,224]	0	hSpCas9	negative selection	924139
132923461	132923484	9	-	26627737	GBM cells	viability after 5 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.12563871701816653	[569]	[293,372]	2	hSpCas9	negative selection	924140
132925661	132925684	9	+	26627737	GBM cells	viability after 5 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.7440047606355334	[672]	[259,170]	-8	hSpCas9	negative selection	924141
132910617	132910640	9	+	26627737	GBM cells	viability after 13 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.05545292197837637	[87]	[42,54]	0	hSpCas9	negative selection	1006451
132911522	132911545	9	+	26627737	GBM cells	viability after 13 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.7344535597871289	[517]	[158,176]	-7	hSpCas9	negative selection	1006452
132921373	132921396	9	-	26627737	GBM cells	viability after 13 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.21621077360608076	[382]	[295,196]	2	hSpCas9	negative selection	1006453
132921926	132921949	9	+	26627737	GBM cells	viability after 13 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.45686644222338824	[401]	[116,192]	-5	hSpCas9	negative selection	1006454
132923461	132923484	9	-	26627737	GBM cells	viability after 13 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.2931151186588188	[569]	[475,299]	4	hSpCas9	negative selection	1006455
132925661	132925684	9	+	26627737	GBM cells	viability after 13 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-1.2004109605353395	[672]	[159,157]	-8	hSpCas9	negative selection	1006456
132910617	132910640	9	+	26627737	GBM cells	viability after 21 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.18383079988292872	[87]	[39,43]	-2	hSpCas9	negative selection	1088766
132911522	132911545	9	+	26627737	GBM cells	viability after 21 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.5767942840897117	[517]	[207,170]	-5	hSpCas9	negative selection	1088767
132921373	132921396	9	-	26627737	GBM cells	viability after 21 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.058875464920780995	[382]	[228,172]	0	hSpCas9	negative selection	1088768
132921926	132921949	9	+	26627737	GBM cells	viability after 21 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.4512967943830032	[401]	[165,153]	-4	hSpCas9	negative selection	1088769
132923461	132923484	9	-	26627737	GBM cells	viability after 21 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.38675784140746594	[569]	[442,369]	4	hSpCas9	negative selection	1088770
132925661	132925684	9	+	26627737	GBM cells	viability after 21 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-2.0792305803944555	[672]	[85,86]	-9	hSpCas9	negative selection	1088771
132910617	132910640	9	+	26627737	RPE1	viability after 9 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-1.0371744901679114	[953]	[131,162]	-6	hSpCas9	negative selection	1171081
132911522	132911545	9	+	26627737	RPE1	viability after 9 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.3140120303479763	[1734]	[552,832]	2	hSpCas9	negative selection	1171082
132921373	132921396	9	-	26627737	RPE1	viability after 9 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.06435476727258327	[1355]	[294,635]	0	hSpCas9	negative selection	1171083
132921926	132921949	9	+	26627737	RPE1	viability after 9 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.8404612478153064	[1775]	[830,1207]	5	hSpCas9	negative selection	1171084
132923461	132923484	9	-	26627737	RPE1	viability after 9 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.41674199240547827	[1610]	[495,901]	3	hSpCas9	negative selection	1171085
132925661	132925684	9	+	26627737	RPE1	viability after 9 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	1.9370090798292638	[1325]	[1255,2019]	8	hSpCas9	negative selection	1171086
132910617	132910640	9	+	26627737	RPE1	viability after 12 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.7554345487868335	[953]	[145,157]	-5	hSpCas9	negative selection	1253396
132911522	132911545	9	+	26627737	RPE1	viability after 12 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.5096236544577095	[1734]	[616,712]	3	hSpCas9	negative selection	1253397
132921373	132921396	9	-	26627737	RPE1	viability after 12 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.9262532563874436	[1355]	[413,986]	6	hSpCas9	negative selection	1253398
132921926	132921949	9	+	26627737	RPE1	viability after 12 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	1.0914346855495856	[1775]	[871,1169]	6	hSpCas9	negative selection	1253399
132923461	132923484	9	-	26627737	RPE1	viability after 12 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.7064787388133396	[1610]	[681,731]	4	hSpCas9	negative selection	1253400
132925661	132925684	9	+	26627737	RPE1	viability after 12 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	2.436221203634222	[1325]	[1693,2175]	9	hSpCas9	negative selection	1253401
132910617	132910640	9	+	26627737	RPE1	viability after 15 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.6823421539592962	[953]	[214,122]	-4	hSpCas9	negative selection	1335711
132911522	132911545	9	+	26627737	RPE1	viability after 15 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	1.0454344966367894	[1734]	[900,1120]	6	hSpCas9	negative selection	1335712
132921373	132921396	9	-	26627737	RPE1	viability after 15 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	1.1843462333678056	[1355]	[689,1046]	6	hSpCas9	negative selection	1335713
132921926	132921949	9	+	26627737	RPE1	viability after 15 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	1.4200292395559453	[1775]	[1436,1254]	7	hSpCas9	negative selection	1335714
132923461	132923484	9	-	26627737	RPE1	viability after 15 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.7731775193402082	[1610]	[731,823]	5	hSpCas9	negative selection	1335715
132925661	132925684	9	+	26627737	RPE1	viability after 15 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	2.783759969057512	[1325]	[2212,2939]	9	hSpCas9	negative selection	1335716
132910617	132910640	9	+	26627737	RPE1	viability after 18 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.56405531639101	[953]	[221,122]	-4	hSpCas9	negative selection	1418026
132911522	132911545	9	+	26627737	RPE1	viability after 18 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	1.6695538352516464	[1734]	[1532,1442]	8	hSpCas9	negative selection	1418027
132921373	132921396	9	-	26627737	RPE1	viability after 18 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	1.707825120540337	[1355]	[988,1415]	8	hSpCas9	negative selection	1418028
132921926	132921949	9	+	26627737	RPE1	viability after 18 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	1.5787912099340464	[1775]	[1277,1595]	8	hSpCas9	negative selection	1418029
132923461	132923484	9	-	26627737	RPE1	viability after 18 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.0080895834094719	[1610]	[725,1032]	6	hSpCas9	negative selection	1418030
132925661	132925684	9	+	26627737	RPE1	viability after 18 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	3.412566902823162	[1325]	[3212,4448]	9	hSpCas9	negative selection	1418031
132910617	132910640	9	+	26627737	HeLa	viability after 8 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.6834135844710683	[115]	[38,114,79]	6	hSpCas9	negative selection	1500341
132911522	132911545	9	+	26627737	HeLa	viability after 8 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.11212016191154761	[590]	[170,430,212]	1	hSpCas9	negative selection	1500342
132921373	132921396	9	-	26627737	HeLa	viability after 8 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.012073042706599368	[684]	[366,232,301]	0	hSpCas9	negative selection	1500343
132921926	132921949	9	+	26627737	HeLa	viability after 8 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.00026610209284294584	[899]	[375,453,344]	0	hSpCas9	negative selection	1500344
132923461	132923484	9	-	26627737	HeLa	viability after 8 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.9709854869412026	[567]	[366,478,574]	7	hSpCas9	negative selection	1500345
132925661	132925684	9	+	26627737	HeLa	viability after 8 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.10486641371311278	[945]	[424,424,471]	1	hSpCas9	negative selection	1500346
132910617	132910640	9	+	26627737	HeLa	viability after 12 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.5314641677046068	[115]	[68,67,70]	4	hSpCas9	negative selection	1582656
132911522	132911545	9	+	26627737	HeLa	viability after 12 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.02590858930518647	[590]	[269,263,183]	0	hSpCas9	negative selection	1582657
132921373	132921396	9	-	26627737	HeLa	viability after 12 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.3362550699818321	[684]	[527,150,419]	3	hSpCas9	negative selection	1582658
132921926	132921949	9	+	26627737	HeLa	viability after 12 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.22032973979265313	[899]	[587,408,309]	2	hSpCas9	negative selection	1582659
132923461	132923484	9	-	26627737	HeLa	viability after 12 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.4075653557115926	[567]	[548,556,766]	8	hSpCas9	negative selection	1582660
132925661	132925684	9	+	26627737	HeLa	viability after 12 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.4654278926216129	[945]	[183,429,216]	-4	hSpCas9	negative selection	1582661
132910617	132910640	9	+	26627737	HeLa	viability after 15 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.032305113600249014	[115]	[14,76,46]	0	hSpCas9	negative selection	1664971
132911522	132911545	9	+	26627737	HeLa	viability after 15 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.4674364512577223	[590]	[189,191,136]	-4	hSpCas9	negative selection	1664972
132921373	132921396	9	-	26627737	HeLa	viability after 15 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.32755640861405433	[684]	[96,267,309]	-3	hSpCas9	negative selection	1664973
132921926	132921949	9	+	26627737	HeLa	viability after 15 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.2938651700989765	[899]	[423,532,385]	2	hSpCas9	negative selection	1664974
132923461	132923484	9	-	26627737	HeLa	viability after 15 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.9859423521738379	[567]	[289,532,560]	7	hSpCas9	negative selection	1664975
132925661	132925684	9	+	26627737	HeLa	viability after 15 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.665907690249299	[945]	[186,237,308]	-5	hSpCas9	negative selection	1664976
132910617	132910640	9	+	26627737	HeLa	viability after 18 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.05991350233187642	[115]	[10,69,46]	0	hSpCas9	negative selection	1747286
132911522	132911545	9	+	26627737	HeLa	viability after 18 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.4583802633485674	[590]	[127,160,136]	-4	hSpCas9	negative selection	1747287
132921373	132921396	9	-	26627737	HeLa	viability after 18 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.32226783873544707	[684]	[68,218,309]	-3	hSpCas9	negative selection	1747288
132921926	132921949	9	+	26627737	HeLa	viability after 18 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.29854646388972417	[899]	[281,447,385]	2	hSpCas9	negative selection	1747289
132923461	132923484	9	-	26627737	HeLa	viability after 18 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.9852122635440427	[567]	[203,428,560]	7	hSpCas9	negative selection	1747290
132925661	132925684	9	+	26627737	HeLa	viability after 18 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.6693554196487957	[945]	[121,199,308]	-5	hSpCas9	negative selection	1747291
132910617	132910640	9	+	26627737	HCT116	viability after 6 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	3.3144832827261976	[181]	[11,434]	9	hSpCas9	negative selection	1829601
132911522	132911545	9	+	26627737	HCT116	viability after 6 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	1.750427688207381	[633]	[393,302]	8	hSpCas9	negative selection	1829602
132921373	132921396	9	-	26627737	HCT116	viability after 6 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.32220794251448737	[1160]	[96,172]	-2	hSpCas9	negative selection	1829603
132921926	132921949	9	+	26627737	HCT116	viability after 6 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.7485978430367739	[1466]	[420,368]	4	hSpCas9	negative selection	1829604
132923461	132923484	9	-	26627737	HCT116	viability after 6 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-0.08594542486909562	[1267]	[259,147]	0	hSpCas9	negative selection	1829605
132925661	132925684	9	+	26627737	HCT116	viability after 6 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.9599825034971772	[1448]	[640,333]	5	hSpCas9	negative selection	1829606
132910617	132910640	9	+	26627737	HCT116	viability after 8 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.10707566610786534	[137]	[50,99,93]	1	hSpCas9	negative selection	1911916
132911522	132911545	9	+	26627737	HCT116	viability after 8 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.2733828589072417	[511]	[295,371,353]	3	hSpCas9	negative selection	1911917
132921373	132921396	9	-	26627737	HCT116	viability after 8 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.5376514694718224	[413]	[253,318,417]	5	hSpCas9	negative selection	1911918
132921926	132921949	9	+	26627737	HCT116	viability after 8 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.15739233754189463	[788]	[390,663,398]	1	hSpCas9	negative selection	1911919
132923461	132923484	9	-	26627737	HCT116	viability after 8 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.29723861407343977	[727]	[567,491,420]	3	hSpCas9	negative selection	1911920
132925661	132925684	9	+	26627737	HCT116	viability after 8 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	1.7453909531021488	[320]	[537,632,606]	9	hSpCas9	negative selection	1911921
132910617	132910640	9	+	26627737	HCT116	viability after 9 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-2.996341258913149	[181]	[9,2]	-9	hSpCas9	negative selection	1994231
132911522	132911545	9	+	26627737	HCT116	viability after 9 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.461046066368391	[633]	[208,54]	-3	hSpCas9	negative selection	1994232
132921373	132921396	9	-	26627737	HCT116	viability after 9 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.39351939615025666	[1160]	[235,235]	-3	hSpCas9	negative selection	1994233
132921926	132921949	9	+	26627737	HCT116	viability after 9 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.3459487270147654	[1466]	[415,222]	-2	hSpCas9	negative selection	1994234
132923461	132923484	9	-	26627737	HCT116	viability after 9 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.3721795024641288	[1267]	[478,405]	2	hSpCas9	negative selection	1994235
132925661	132925684	9	+	26627737	HCT116	viability after 9 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.4866214118708858	[1448]	[374,197]	-3	hSpCas9	negative selection	1994236
132910617	132910640	9	+	26627737	HCT116	viability after 12 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.3762651839951441	[137]	[79,108,94]	4	hSpCas9	negative selection	2076546
132911522	132911545	9	+	26627737	HCT116	viability after 12 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.1512503610604865	[511]	[235,224,265]	-1	hSpCas9	negative selection	2076547
132921373	132921396	9	-	26627737	HCT116	viability after 12 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.21803570013372814	[413]	[212,264,284]	2	hSpCas9	negative selection	2076548
132921926	132921949	9	+	26627737	HCT116	viability after 12 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.6764376867984152	[788]	[532,686,779]	6	hSpCas9	negative selection	2076549
132923461	132923484	9	-	26627737	HCT116	viability after 12 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.346455539214491	[727]	[515,457,481]	3	hSpCas9	negative selection	2076550
132925661	132925684	9	+	26627737	HCT116	viability after 12 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	1.473001038716028	[320]	[505,444,449]	9	hSpCas9	negative selection	2076551
132910617	132910640	9	+	26627737	HCT116	viability after 15 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.07831941801260367	[137]	[70,54,122]	0	hSpCas9	negative selection	2158861
132911522	132911545	9	+	26627737	HCT116	viability after 15 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.09012406377373006	[511]	[327,230,275]	-1	hSpCas9	negative selection	2158862
132921373	132921396	9	-	26627737	HCT116	viability after 15 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.5301953155879446	[413]	[412,237,386]	5	hSpCas9	negative selection	2158863
132921926	132921949	9	+	26627737	HCT116	viability after 15 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.7123010903595934	[788]	[549,1012,641]	6	hSpCas9	negative selection	2158864
132923461	132923484	9	-	26627737	HCT116	viability after 15 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.32691588194403276	[727]	[764,517,321]	3	hSpCas9	negative selection	2158865
132925661	132925684	9	+	26627737	HCT116	viability after 15 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	1.625698345896093	[320]	[546,505,649]	9	hSpCas9	negative selection	2158866
132910617	132910640	9	+	26627737	HCT116	viability after 18 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.7551691440240034	[137]	[86,112,138]	6	hSpCas9	negative selection	2241176
132911522	132911545	9	+	26627737	HCT116	viability after 18 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.02380609284160884	[511]	[173,282,297]	0	hSpCas9	negative selection	2241177
132921373	132921396	9	-	26627737	HCT116	viability after 18 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.48066444915409706	[413]	[387,241,206]	4	hSpCas9	negative selection	2241178
132921926	132921949	9	+	26627737	HCT116	viability after 18 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.9688128373336784	[788]	[460,1143,601]	7	hSpCas9	negative selection	2241179
132923461	132923484	9	-	26627737	HCT116	viability after 18 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.2299893273960687	[727]	[688,327,217]	2	hSpCas9	negative selection	2241180
132925661	132925684	9	+	26627737	HCT116	viability after 18 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	2.2581500503968814	[320]	[751,696,782]	9	hSpCas9	negative selection	2241181
132927209	132927232	9	+	24336569	HL60	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	0.26542833812383515	[549]	[1398]	2	hSpCas9	negative selection	2303797
132927223	132927246	9	+	24336569	HL60	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	0.9623901889605311	[1376]	[5677]	7	hSpCas9	negative selection	2303798
132927234	132927257	9	+	24336569	HL60	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	-0.18071033791825447	[533]	[996]	-1	hSpCas9	negative selection	2303799
132927242	132927265	9	-	24336569	HL60	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	1.6803761621763393	[68]	[467]	9	hSpCas9	negative selection	2303800
132927258	132927281	9	+	24336569	HL60	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	1.7620625734592912	[421]	[3028]	9	hSpCas9	negative selection	2303801
132927272	132927295	9	-	24336569	HL60	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	0.7001223744880709	[346]	[1192]	6	hSpCas9	negative selection	2303802
132927281	132927304	9	+	24336569	HL60	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	1.0354261384915477	[313]	[1361]	7	hSpCas9	negative selection	2303803
132928766	132928789	9	-	24336569	HL60	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	0.1942513808858801	[386]	[936]	2	hSpCas9	negative selection	2303804
132928801	132928824	9	+	24336569	HL60	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	0.43945567129809926	[997]	[2863]	4	hSpCas9	negative selection	2303805
132928849	132928872	9	-	24336569	HL60	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.7572214143501	[923]	[3304]	6	hSpCas9	negative selection	2303806
132927209	132927232	9	+	24336569	KBM7	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	-1.1397568689682507	[369]	[457]	-7	hSpCas9	negative selection	2370974
132927223	132927246	9	+	24336569	KBM7	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	0.2501088060787866	[766]	[2487]	2	hSpCas9	negative selection	2370975
132927234	132927257	9	+	24336569	KBM7	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	-0.16765301131631574	[466]	[1133]	-1	hSpCas9	negative selection	2370976
132927242	132927265	9	-	24336569	KBM7	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	0.35686999433331046	[70]	[247]	3	hSpCas9	negative selection	2370977
132927258	132927281	9	+	24336569	KBM7	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	0.14496647559133802	[505]	[1525]	1	hSpCas9	negative selection	2370978
132927272	132927295	9	-	24336569	KBM7	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	1.9656716832559469	[201]	[2151]	9	hSpCas9	negative selection	2370979
132927281	132927304	9	+	24336569	KBM7	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	1.6946894619905646	[157]	[1394]	9	hSpCas9	negative selection	2370980
132928766	132928789	9	-	24336569	KBM7	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	0.9418820560239451	[312]	[1639]	7	hSpCas9	negative selection	2370981
132928801	132928824	9	+	24336569	KBM7	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	0.6531410837271979	[770]	[3306]	6	hSpCas9	negative selection	2370982
132928849	132928872	9	-	24336569	KBM7	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.3019804888044837	[843]	[2837]	2	hSpCas9	negative selection	2370983
132928807	132928831	9	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GACTCCCCCATGCTGGGTGTGCGG	TSC1	ENSG00000165699	1.620070572869572	[645,1077,720]	[0,0,0]	5	hSpCas9	positive selection	2381516
132927275	132927299	9	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCCCTATGCTTGTAAACACCTTGG	TSC1	ENSG00000165699	5.688511365442038	[28,50,64]	[0,0,0]	7	hSpCas9	positive selection	2381517
132925709	132925731	9	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GACAGGATTAACGAATATGTGG	TSC1	ENSG00000165699	0.3208555529235977	[2613,1665,1812]	[0,0,0]	1	hSpCas9	positive selection	2381518
132928807	132928831	9	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GACTCCCCCATGCTGGGTGTGCGG	TSC1	ENSG00000165699	1.6188657372448092	[645,1077,720]	[0,0,0]	4	hSpCas9	positive selection	2382959
132927275	132927299	9	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCCCTATGCTTGTAAACACCTTGG	TSC1	ENSG00000165699	5.6890793823809815	[28,50,64]	[0,0,0]	8	hSpCas9	positive selection	2382960
132925709	132925731	9	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GACAGGATTAACGAATATGTGG	TSC1	ENSG00000165699	0.32079304663841235	[2613,1665,1812]	[0,0,0]	0	hSpCas9	positive selection	2382961
132921915	132921938	9	+	27260157	DLD1	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.249707760758608	[]	[]	-2	hSpCas9	negative selection	2573892
132925627	132925650	9	+	27260157	DLD1	viability	GAGAGCTTATGCTTCCAAGATGG	TSC1	ENSG00000165699	-0.4036149401917	[]	[]	-3	hSpCas9	negative selection	2574819
132921406	132921429	9	-	27260157	DLD1	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.694360928540554	[]	[]	8	hSpCas9	negative selection	2575572
132928801	132928824	9	+	27260157	DLD1	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	-0.548424184420628	[]	[]	-4	hSpCas9	negative selection	2586759
132927258	132927281	9	+	27260157	DLD1	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	1.91198461223727	[]	[]	9	hSpCas9	negative selection	2604498
132928869	132928892	9	-	27260157	DLD1	viability	AGCGCCTTCGAGCGAGAGAATGG	TSC1	ENSG00000165699	-0.159384147486178	[]	[]	-1	hSpCas9	negative selection	2605613
132911463	132911486	9	+	27260157	DLD1	viability	TCAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.763400075595225	[]	[]	8	hSpCas9	negative selection	2607722
132927234	132927257	9	+	27260157	DLD1	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	-0.965720931662103	[]	[]	-7	hSpCas9	negative selection	2607960
132921361	132921384	9	+	27260157	DLD1	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	-0.506385001698186	[]	[]	-4	hSpCas9	negative selection	2607963
132912317	132912340	9	+	27260157	DLD1	viability	GTGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	1.20461789276764	[]	[]	9	hSpCas9	negative selection	2609358
132927281	132927304	9	+	27260157	DLD1	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	-0.161699285800848	[]	[]	-1	hSpCas9	negative selection	2611668
132928766	132928789	9	-	27260157	DLD1	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	0.169563814464346	[]	[]	3	hSpCas9	negative selection	2618714
132927242	132927265	9	-	27260157	DLD1	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	0.717070294940425	[]	[]	8	hSpCas9	negative selection	2619486
132927209	132927232	9	+	27260157	DLD1	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	0.11542753949264	[]	[]	3	hSpCas9	negative selection	2619540
132928865	132928888	9	+	27260157	DLD1	viability	TGGGCCATTCTCTCGCTCGAAGG	TSC1	ENSG00000165699	0.507874243922427	[]	[]	8	hSpCas9	negative selection	2623775
132927223	132927246	9	+	27260157	DLD1	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	-1.06895354444308	[]	[]	-7	hSpCas9	negative selection	2624093
132927272	132927295	9	-	27260157	DLD1	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	-0.513177418549473	[]	[]	-4	hSpCas9	negative selection	2644391
132925661	132925684	9	+	27260157	DLD1	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.495068324628827	[]	[]	-4	hSpCas9	negative selection	2645262
132928849	132928872	9	-	27260157	DLD1	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.262174520379397	[]	[]	4	hSpCas9	negative selection	2646401
132928848	132928871	9	-	27260157	DLD1	viability	GGCCCAACAAGCAAATGTCGGGG	TSC1	ENSG00000165699	-0.0780756719185035	[]	[]	0	hSpCas9	negative selection	2648846
132921915	132921938	9	+	27260157	HT1080	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.884739683611546	[]	[]	-8	hSpCas9	negative selection	2650022
132925627	132925650	9	+	27260157	HT1080	viability	GAGAGCTTATGCTTCCAAGATGG	TSC1	ENSG00000165699	-0.405001550113055	[]	[]	-7	hSpCas9	negative selection	2650949
132921406	132921429	9	-	27260157	HT1080	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.0499916754375619	[]	[]	0	hSpCas9	negative selection	2651702
132928801	132928824	9	+	27260157	HT1080	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	0.519557189709231	[]	[]	4	hSpCas9	negative selection	2662889
132927258	132927281	9	+	27260157	HT1080	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	0.0279304021855354	[]	[]	0	hSpCas9	negative selection	2680628
132928869	132928892	9	-	27260157	HT1080	viability	AGCGCCTTCGAGCGAGAGAATGG	TSC1	ENSG00000165699	-0.478489453489179	[]	[]	-7	hSpCas9	negative selection	2681743
132911463	132911486	9	+	27260157	HT1080	viability	TCAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.218336968651354	[]	[]	2	hSpCas9	negative selection	2683852
132927234	132927257	9	+	27260157	HT1080	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	0.119059445579251	[]	[]	1	hSpCas9	negative selection	2684090
132921361	132921384	9	+	27260157	HT1080	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.176328217478292	[]	[]	1	hSpCas9	negative selection	2684093
132912317	132912340	9	+	27260157	HT1080	viability	GTGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-0.0469964825550024	[]	[]	0	hSpCas9	negative selection	2685488
132927281	132927304	9	+	27260157	HT1080	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	-0.191624410299587	[]	[]	0	hSpCas9	negative selection	2687798
132928766	132928789	9	-	27260157	HT1080	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	-0.504235632263147	[]	[]	-7	hSpCas9	negative selection	2694844
132927242	132927265	9	-	27260157	HT1080	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	0.391726147075204	[]	[]	3	hSpCas9	negative selection	2695616
132927209	132927232	9	+	27260157	HT1080	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	-0.895163504776909	[]	[]	-8	hSpCas9	negative selection	2695670
132928865	132928888	9	+	27260157	HT1080	viability	TGGGCCATTCTCTCGCTCGAAGG	TSC1	ENSG00000165699	1.40716848506852	[]	[]	9	hSpCas9	negative selection	2699905
132927223	132927246	9	+	27260157	HT1080	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	-1.41706012246581	[]	[]	-9	hSpCas9	negative selection	2700223
132927272	132927295	9	-	27260157	HT1080	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	-2.27587390833988	[]	[]	-9	hSpCas9	negative selection	2720521
132925661	132925684	9	+	27260157	HT1080	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.447133335516325	[]	[]	4	hSpCas9	negative selection	2721392
132928849	132928872	9	-	27260157	HT1080	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.316253214090465	[]	[]	3	hSpCas9	negative selection	2722531
132928848	132928871	9	-	27260157	HT1080	viability	GGCCCAACAAGCAAATGTCGGGG	TSC1	ENSG00000165699	0.7184839243604	[]	[]	6	hSpCas9	negative selection	2724976
132921915	132921938	9	+	27260157	MKN45	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-2.88109954930564	[]	[]	-9	hSpCas9	negative selection	2726152
132925627	132925650	9	+	27260157	MKN45	viability	GAGAGCTTATGCTTCCAAGATGG	TSC1	ENSG00000165699	-0.382139323037384	[]	[]	-1	hSpCas9	negative selection	2727079
132921406	132921429	9	-	27260157	MKN45	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-2.22185238826412	[]	[]	-9	hSpCas9	negative selection	2727832
132928801	132928824	9	+	27260157	MKN45	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	-0.575530855464306	[]	[]	-6	hSpCas9	negative selection	2739019
132927258	132927281	9	+	27260157	MKN45	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	-0.948939417926499	[]	[]	-7	hSpCas9	negative selection	2756758
132928869	132928892	9	-	27260157	MKN45	viability	AGCGCCTTCGAGCGAGAGAATGG	TSC1	ENSG00000165699	2.54847854586587	[]	[]	9	hSpCas9	negative selection	2757873
132911463	132911486	9	+	27260157	MKN45	viability	TCAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-0.519376631279593	[]	[]	-6	hSpCas9	negative selection	2759982
132927234	132927257	9	+	27260157	MKN45	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	-0.86064333679617	[]	[]	-7	hSpCas9	negative selection	2760220
132921361	132921384	9	+	27260157	MKN45	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	-0.30242024477026	[]	[]	-1	hSpCas9	negative selection	2760223
132912317	132912340	9	+	27260157	MKN45	viability	GTGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-1.33454014390639	[]	[]	-8	hSpCas9	negative selection	2761618
132927281	132927304	9	+	27260157	MKN45	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	-0.4691457359797	[]	[]	-6	hSpCas9	negative selection	2763928
132928766	132928789	9	-	27260157	MKN45	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	-1.69889323241999	[]	[]	-9	hSpCas9	negative selection	2770974
132927242	132927265	9	-	27260157	MKN45	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	-0.568503296266443	[]	[]	-6	hSpCas9	negative selection	2771746
132927209	132927232	9	+	27260157	MKN45	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	-1.52996209295102	[]	[]	-9	hSpCas9	negative selection	2771800
132928865	132928888	9	+	27260157	MKN45	viability	TGGGCCATTCTCTCGCTCGAAGG	TSC1	ENSG00000165699	1.81764634113884	[]	[]	9	hSpCas9	negative selection	2776035
132927223	132927246	9	+	27260157	MKN45	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	-3.6091858710015	[]	[]	-9	hSpCas9	negative selection	2776353
132927272	132927295	9	-	27260157	MKN45	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	-1.55534765225659	[]	[]	-9	hSpCas9	negative selection	2796651
132925661	132925684	9	+	27260157	MKN45	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-1.16623410772725	[]	[]	-8	hSpCas9	negative selection	2797522
132928849	132928872	9	-	27260157	MKN45	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	-1.31048436829054	[]	[]	-8	hSpCas9	negative selection	2798661
132928848	132928871	9	-	27260157	MKN45	viability	GGCCCAACAAGCAAATGTCGGGG	TSC1	ENSG00000165699	-0.151090834370704	[]	[]	0	hSpCas9	negative selection	2801106
132921915	132921938	9	+	27260157	RKO	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.770105413945461	[]	[]	-7	hSpCas9	negative selection	2802282
132925627	132925650	9	+	27260157	RKO	viability	GAGAGCTTATGCTTCCAAGATGG	TSC1	ENSG00000165699	-0.296486241529101	[]	[]	-6	hSpCas9	negative selection	2803209
132921406	132921429	9	-	27260157	RKO	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.915246015611464	[]	[]	-8	hSpCas9	negative selection	2803962
132928801	132928824	9	+	27260157	RKO	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	-1.12123114003766	[]	[]	-8	hSpCas9	negative selection	2815149
132927258	132927281	9	+	27260157	RKO	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	0.910172683250315	[]	[]	8	hSpCas9	negative selection	2832888
132928869	132928892	9	-	27260157	RKO	viability	AGCGCCTTCGAGCGAGAGAATGG	TSC1	ENSG00000165699	-0.590979426047452	[]	[]	-7	hSpCas9	negative selection	2834003
132911463	132911486	9	+	27260157	RKO	viability	TCAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.00608916897793392	[]	[]	0	hSpCas9	negative selection	2836112
132927234	132927257	9	+	27260157	RKO	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	-0.55325878626991	[]	[]	-7	hSpCas9	negative selection	2836350
132921361	132921384	9	+	27260157	RKO	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.785479814966613	[]	[]	8	hSpCas9	negative selection	2836353
132912317	132912340	9	+	27260157	RKO	viability	GTGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-0.313099480286567	[]	[]	-6	hSpCas9	negative selection	2837748
132927281	132927304	9	+	27260157	RKO	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	-0.0337222809013899	[]	[]	0	hSpCas9	negative selection	2840058
132928766	132928789	9	-	27260157	RKO	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	-0.331753285149281	[]	[]	-6	hSpCas9	negative selection	2847104
132927242	132927265	9	-	27260157	RKO	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	0.518464916544266	[]	[]	2	hSpCas9	negative selection	2847876
132927209	132927232	9	+	27260157	RKO	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	-0.204431241649751	[]	[]	-1	hSpCas9	negative selection	2847930
132928865	132928888	9	+	27260157	RKO	viability	TGGGCCATTCTCTCGCTCGAAGG	TSC1	ENSG00000165699	1.09714898995493	[]	[]	9	hSpCas9	negative selection	2852165
132927223	132927246	9	+	27260157	RKO	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	-0.94229721680929	[]	[]	-8	hSpCas9	negative selection	2852483
132927272	132927295	9	-	27260157	RKO	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	-0.455473095489807	[]	[]	-6	hSpCas9	negative selection	2872781
132925661	132925684	9	+	27260157	RKO	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.343765210798642	[]	[]	1	hSpCas9	negative selection	2873652
132928849	132928872	9	-	27260157	RKO	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.0955792575641459	[]	[]	0	hSpCas9	negative selection	2874791
132928848	132928871	9	-	27260157	RKO	viability	GGCCCAACAAGCAAATGTCGGGG	TSC1	ENSG00000165699	-0.663608399640072	[]	[]	-7	hSpCas9	negative selection	2877236
132921915	132921938	9	+	27260157	SF268	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.111604459996825	[]	[]	0	hSpCas9	negative selection	2878412
132925627	132925650	9	+	27260157	SF268	viability	GAGAGCTTATGCTTCCAAGATGG	TSC1	ENSG00000165699	-0.830465981524919	[]	[]	-6	hSpCas9	negative selection	2879339
132921406	132921429	9	-	27260157	SF268	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.0236153228944184	[]	[]	0	hSpCas9	negative selection	2880092
132928801	132928824	9	+	27260157	SF268	viability	GTCGTCCCGCACACCCAGCATGG	TSC1	ENSG00000165699	0.470870582261778	[]	[]	7	hSpCas9	negative selection	2891279
132927258	132927281	9	+	27260157	SF268	viability	TTCCAGGTAATAATCCACCAAGG	TSC1	ENSG00000165699	1.07845871555521	[]	[]	9	hSpCas9	negative selection	2909018
132928869	132928892	9	-	27260157	SF268	viability	AGCGCCTTCGAGCGAGAGAATGG	TSC1	ENSG00000165699	1.13673293078198	[]	[]	9	hSpCas9	negative selection	2910133
132911463	132911486	9	+	27260157	SF268	viability	TCAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-0.166471987027004	[]	[]	-1	hSpCas9	negative selection	2912242
132927234	132927257	9	+	27260157	SF268	viability	GTGCAATGCCGGCTGAGAGCTGG	TSC1	ENSG00000165699	0.0160529960358871	[]	[]	0	hSpCas9	negative selection	2912480
132921361	132921384	9	+	27260157	SF268	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.920288766553232	[]	[]	9	hSpCas9	negative selection	2912483
132912317	132912340	9	+	27260157	SF268	viability	GTGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-0.122614177516844	[]	[]	-1	hSpCas9	negative selection	2913878
132927281	132927304	9	+	27260157	SF268	viability	TGTTTACAAGCATAGGGCCACGG	TSC1	ENSG00000165699	-0.083462325397964	[]	[]	0	hSpCas9	negative selection	2916188
132928766	132928789	9	-	27260157	SF268	viability	TTTAAAGAGAACCTCAATTCTGG	TSC1	ENSG00000165699	-0.643121286110589	[]	[]	-5	hSpCas9	negative selection	2923234
132927242	132927265	9	-	27260157	SF268	viability	CCTGGAAACCAGCTCTCAGCCGG	TSC1	ENSG00000165699	-0.140413643412861	[]	[]	-1	hSpCas9	negative selection	2924006
132927209	132927232	9	+	27260157	SF268	viability	GTGGCTCTTGCAAGGTGGTCAGG	TSC1	ENSG00000165699	-0.534107826755979	[]	[]	-4	hSpCas9	negative selection	2924060
132928865	132928888	9	+	27260157	SF268	viability	TGGGCCATTCTCTCGCTCGAAGG	TSC1	ENSG00000165699	1.16630436877825	[]	[]	9	hSpCas9	negative selection	2928295
132927223	132927246	9	+	27260157	SF268	viability	GTGGTCAGGATGTGCAATGCCGG	TSC1	ENSG00000165699	-0.885396692679324	[]	[]	-6	hSpCas9	negative selection	2928613
132927272	132927295	9	-	27260157	SF268	viability	TATGCTTGTAAACACCTTGGTGG	TSC1	ENSG00000165699	-0.833785243730552	[]	[]	-6	hSpCas9	negative selection	2948911
132925661	132925684	9	+	27260157	SF268	viability	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	0.0842902600065814	[]	[]	0	hSpCas9	negative selection	2949782
132928849	132928872	9	-	27260157	SF268	viability	TGGCCCAACAAGCAAATGTCGGG	TSC1	ENSG00000165699	0.0434972469394991	[]	[]	0	hSpCas9	negative selection	2950921
132928848	132928871	9	-	27260157	SF268	viability	GGCCCAACAAGCAAATGTCGGGG	TSC1	ENSG00000165699	-0.476669644306028	[]	[]	-4	hSpCas9	negative selection	2953366
132906027	132906050	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	-0.5892010639990948	[4,4]	[3,0]	-7	hSpCas9	positive selection	3029548
132905899	132905922	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	-0.8625842820863668	[3,3]	[2,0]	-8	hSpCas9	positive selection	3029549
132905885	132905908	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	0.1670971136703618	[3,3]	[3,2]	3	hSpCas9	positive selection	3029550
132923358	132923381	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	0.03486326281357677	[4,4]	[5,3]	0	hSpCas9	positive selection	3029551
132906027	132906050	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	0.33726369858210303	[4,4]	[5,2]	6	hSpCas9	positive selection	3097406
132905899	132905922	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	-0.8707543103321761	[3,3]	[2,0]	-9	hSpCas9	positive selection	3097407
132905885	132905908	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	-0.23289534079005897	[3,3]	[2,1]	-3	hSpCas9	positive selection	3097408
132923358	132923381	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	-0.23724556947702133	[4,4]	[3,1]	-3	hSpCas9	positive selection	3097409
132921361	132921384		+	24336571	A375	resistance to PLX after 7 days	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.09357315789318643	[37,42]	[43,41]	3	hSpCas9	positive selection	3152991
132921950	132921973		+	24336571	A375	resistance to PLX after 7 days	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.3186517266630452	[16,21]	[23,23]	8	hSpCas9	positive selection	3152992
132921406	132921429		-	24336571	A375	resistance to PLX after 7 days	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.04748269271380523	[23,26]	[25,25]	1	hSpCas9	positive selection	3152993
132921361	132921384		+	24336571	A375	resistance to PLX after 14 days	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.49347844818899755	[44,50]	[28,33]	4	hSpCas9	positive selection	3210784
132921950	132921973		+	24336571	A375	resistance to PLX after 14 days	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.10875075981725724	[26,17]	[10,7]	-1	hSpCas9	positive selection	3210785
132921406	132921429		-	24336571	A375	resistance to PLX after 14 days	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.11500883588063182	[26,24]	[8,15]	1	hSpCas9	positive selection	3210786
132921361	132921384		+	24336571	A375	viability after 7 days	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.727710268170136	[25]	[37,42]	9	hSpCas9	negative selection	3268577
132921950	132921973		+	24336571	A375	viability after 7 days	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.07718386230945185	[18]	[16,21]	1	hSpCas9	negative selection	3268578
132921406	132921429		-	24336571	A375	viability after 7 days	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.12617775555532107	[24]	[23,26]	2	hSpCas9	negative selection	3268579
132921361	132921384		+	24336571	A375	viability after 14 days	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.9943759959656668	[25]	[44,50]	9	hSpCas9	negative selection	3326370
132921950	132921973		+	24336571	A375	viability after 14 days	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.2937383771762915	[18]	[26,17]	4	hSpCas9	negative selection	3326371
132921406	132921429		-	24336571	A375	viability after 14 days	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.14919633468938243	[24]	[26,24]	2	hSpCas9	negative selection	3326372
132925670	132925693	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	-0.9423461333905293	[293,293]	[0,0]	-6	hSpCas9	positive selection	3399285
132921361	132921384	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	-0.8459615969661868	[274,274]	[0,0]	-6	hSpCas9	positive selection	3399286
132925715	132925738	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.2464995265499157	[362,362]	[0,0]	-8	hSpCas9	positive selection	3399287
132906027	132906050	9	-	26780180	HT29	viability (Avana library 4 designs)	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	0.434946658515899	[]	[]	1	hSpCas9	negative selection	3468407
132905899	132905922	9	-	26780180	HT29	viability (Avana library 4 designs)	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	1.07176904368811	[]	[]	4	hSpCas9	negative selection	3468408
132905884	132905907	9	+	26780180	HT29	viability (Avana library 4 designs)	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	0.0195834351400609	[]	[]	0	hSpCas9	negative selection	3468409
132923357	132923380	9	+	26780180	HT29	viability (Avana library 4 designs)	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	-0.0103711825864854	[]	[]	0	hSpCas9	negative selection	3468410
132905899	132905922	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	-7.7129480466272	[]	[]	-7	hSpCas9	negative selection	3573064
132905884	132905907	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	-5.57531421973421	[]	[]	-6	hSpCas9	negative selection	3573065
132906027	132906050	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	-7.21662538160555	[]	[]	-6	hSpCas9	negative selection	3573066
132923357	132923380	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	-0.948998672998764	[]	[]	-1	hSpCas9	negative selection	3573067
132911510	132911533	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGTTGTTAAATATGCCAGGG	TSC1	ENSG00000165699	-13.1840874669599	[]	[]	-8	hSpCas9	negative selection	3573068
132912304	132912327	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAAGGGCTGGTGGTGACATCGG	TSC1	ENSG00000165699	-2.53571045091235	[]	[]	-3	hSpCas9	negative selection	3573069
132905899	132905922	9	-	26780180	A375	viability (Avana lentiGuide)	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	9.48867629906174	[]	[]	6	hSpCas9	negative selection	3681723
132905884	132905907	9	+	26780180	A375	viability (Avana lentiGuide)	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	4.74383864761319	[]	[]	4	hSpCas9	negative selection	3681724
132906027	132906050	9	-	26780180	A375	viability (Avana lentiGuide)	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	25.9229134044685	[]	[]	9	hSpCas9	negative selection	3681725
132923357	132923380	9	+	26780180	A375	viability (Avana lentiGuide)	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	3.74331858596928	[]	[]	3	hSpCas9	negative selection	3681726
132911510	132911533	9	-	26780180	A375	viability (Avana lentiGuide)	TGATGTTGTTAAATATGCCAGGG	TSC1	ENSG00000165699	12.5788671785027	[]	[]	7	hSpCas9	negative selection	3681727
132912304	132912327	9	+	26780180	A375	viability (Avana lentiGuide)	ATAAGGGCTGGTGGTGACATCGG	TSC1	ENSG00000165699	15.2697024084109	[]	[]	8	hSpCas9	negative selection	3681728
132905899	132905922	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	-0.36091942617658535	[4]	[3,3]	-5	hSpCas9	positive selection	3790330
132905884	132905907	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	-0.6627383476229025	[4]	[3,1]	-7	hSpCas9	positive selection	3790331
132906027	132906050	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	-0.11200769583048491	[5]	[5,4]	-2	hSpCas9	positive selection	3790332
132923357	132923380	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	0.09256537375599311	[5]	[5,5]	2	hSpCas9	positive selection	3790333
132911510	132911533	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGTTGTTAAATATGCCAGGG	TSC1	ENSG00000165699	-0.9714556807735241	[7]	[4,2]	-8	hSpCas9	positive selection	3790334
132912304	132912327	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAAGGGCTGGTGGTGACATCGG	TSC1	ENSG00000165699	-0.22112584300132532	[5]	[3,4]	-3	hSpCas9	positive selection	3790335
132905899	132905922	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCCCATAGACCTGCCCTGCGG	TSC1	ENSG00000165699	-0.7259208821746111	[5]	[2,2]	-7	hSpCas9	positive selection	3898937
132905884	132905907	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCATCAGCACTGCCGCAGGG	TSC1	ENSG00000165699	-0.859576600685566	[4]	[1,2]	-8	hSpCas9	positive selection	3898938
132906027	132906050	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGTCTCCCAGGTTCTCAGCGG	TSC1	ENSG00000165699	-0.3118619507705656	[6]	[2,4]	-4	hSpCas9	positive selection	3898939
132923357	132923380	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGGCACCATGATGACAGACGG	TSC1	ENSG00000165699	-0.01327418752699576	[6]	[5,4]	0	hSpCas9	positive selection	3898940
132911510	132911533	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGTTGTTAAATATGCCAGGG	TSC1	ENSG00000165699	-0.5865141537494596	[6]	[3,2]	-6	hSpCas9	positive selection	3898941
132912304	132912327	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAAGGGCTGGTGGTGACATCGG	TSC1	ENSG00000165699	-0.36734737789192573	[5]	[3,2]	-5	hSpCas9	positive selection	3898942
132921361	132921384	9	+	26780180	A375	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.966503674782885	[]	[]	4	hSpCas9	negative selection	4008238
132921915	132921938	9	+	26780180	A375	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	1.89974953871998	[]	[]	9	hSpCas9	negative selection	4008239
132925715	132925738	9	+	26780180	A375	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	1.9239577416319	[]	[]	9	hSpCas9	negative selection	4008240
132921950	132921973	9	+	26780180	A375	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	1.1248031284949	[]	[]	5	hSpCas9	negative selection	4008241
132921406	132921429	9	-	26780180	A375	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	1.55786786586937	[]	[]	8	hSpCas9	negative selection	4008242
132925670	132925693	9	-	26780180	A375	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.266458471047119	[]	[]	0	hSpCas9	negative selection	4008243
132921361	132921384	9	+	26780180	HT29	viability (GeCKOv2 library)	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.930813115233784	[]	[]	4	hSpCas9	negative selection	4116204
132921915	132921938	9	+	26780180	HT29	viability (GeCKOv2 library)	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	1.78184617013884	[]	[]	8	hSpCas9	negative selection	4116205
132925715	132925738	9	+	26780180	HT29	viability (GeCKOv2 library)	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.55114137876387	[]	[]	1	hSpCas9	negative selection	4116206
132921950	132921973	9	+	26780180	HT29	viability (GeCKOv2 library)	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.73171597648211	[]	[]	3	hSpCas9	negative selection	4116207
132921406	132921429	9	-	26780180	HT29	viability (GeCKOv2 library)	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	1.01945028788656	[]	[]	4	hSpCas9	negative selection	4116208
132925670	132925693	9	-	26780180	HT29	viability (GeCKOv2 library)	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.705369083329562	[]	[]	2	hSpCas9	negative selection	4116209
132921361	132921384	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.4243137676576076	[5]	[4,4]	8	hSpCas9	positive selection	4179591
132921950	132921973	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.20059232230053006	[4]	[3,3]	5	hSpCas9	positive selection	4179592
132921406	132921429	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.17765423207382663	[4]	[3,3]	4	hSpCas9	positive selection	4179593
132921361	132921384	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	1.0754379145293478	[4]	[4,4,2,4]	7	hSpCas9	positive selection	4243613
132921950	132921973	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.19022910526054748	[4]	[3,2,0,0]	-3	hSpCas9	positive selection	4243614
132921406	132921429	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.815255432160636	[4]	[4,4,0,4]	5	hSpCas9	positive selection	4243615
132921950	132921973	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.10807664897776068	[3]	[3,2]	2	hSpCas9	positive selection	4305430
132921915	132921938	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.7101260461601887	[3]	[2,0]	-9	hSpCas9	positive selection	4305431
132921406	132921429	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.24443635779544065	[2]	[2,0]	-5	hSpCas9	positive selection	4305432
132925670	132925693	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.3311402272586531	[3]	[3,3]	6	hSpCas9	positive selection	4369679
132921361	132921384	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.30008335534929587	[2]	[3,1]	6	hSpCas9	positive selection	4369680
132925715	132925738	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.19336354617076418	[3]	[3,1]	-4	hSpCas9	positive selection	4369681
132911464	132911486	9	+	27760321	OCIAML3	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.07568837687896457	[797,747]	[551,748]	0	hSpCas9	negative selection	4450507
132911530	132911552	9	+	27760321	OCIAML3	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	-0.25502390370476596	[581,460]	[277,419]	-3	hSpCas9	negative selection	4450508
132912318	132912340	9	+	27760321	OCIAML3	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.6367529402288052	[415,309]	[302,612]	7	hSpCas9	negative selection	4450509
132921393	132921415	9	-	27760321	OCIAML3	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-1.4304020178731363	[257,240]	[71,72]	-8	hSpCas9	negative selection	4450510
132923461	132923483	9	-	27760321	OCIAML3	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-0.10002685712920079	[264,255]	[166,220]	-1	hSpCas9	negative selection	4450511
132911464	132911486	9	+	27760321	OCIAML2	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-0.1937834272669905	[797,747]	[556,533]	-2	hSpCas9	negative selection	4533970
132911530	132911552	9	+	27760321	OCIAML2	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	-0.4706405202082974	[581,460]	[264,351]	-5	hSpCas9	negative selection	4533971
132912318	132912340	9	+	27760321	OCIAML2	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-0.4334440844559032	[415,309]	[196,239]	-5	hSpCas9	negative selection	4533972
132921393	132921415	9	-	27760321	OCIAML2	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-0.5734543206866793	[257,240]	[95,187]	-6	hSpCas9	negative selection	4533973
132923461	132923483	9	-	27760321	OCIAML2	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-1.0077289793631228	[264,255]	[104,104]	-7	hSpCas9	negative selection	4533974
132911464	132911486	9	+	27760321	MV411	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-1.0365511951807953	[797,747]	[40,560]	-6	hSpCas9	negative selection	4617433
132911530	132911552	9	+	27760321	MV411	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	-1.7953388662159588	[581,460]	[12,226]	-8	hSpCas9	negative selection	4617434
132912318	132912340	9	+	27760321	MV411	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	-1.0688428407371187	[415,309]	[109,117]	-6	hSpCas9	negative selection	4617435
132921393	132921415	9	-	27760321	MV411	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-0.49310600449483144	[257,240]	[160,50]	-3	hSpCas9	negative selection	4617436
132923461	132923483	9	-	27760321	MV411	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-1.2943970322126037	[264,255]	[90,38]	-7	hSpCas9	negative selection	4617437
132911464	132911486	9	+	27760321	HL60	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.5665282629920814	[797,747]	[727,1155]	6	hSpCas9	negative selection	4700896
132911530	132911552	9	+	27760321	HL60	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.6146205319426686	[581,460]	[538,763]	7	hSpCas9	negative selection	4700897
132912318	132912340	9	+	27760321	HL60	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.6266604186994389	[415,309]	[481,423]	7	hSpCas9	negative selection	4700898
132921393	132921415	9	-	27760321	HL60	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	0.16197274342598145	[257,240]	[182,275]	2	hSpCas9	negative selection	4700899
132923461	132923483	9	-	27760321	HL60	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.35237390386811973	[264,255]	[277,265]	4	hSpCas9	negative selection	4700900
132911464	132911486	9	+	27760321	HT1080	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.3948554046434065	[747,583]	[313,386]	2	hSpCas9	negative selection	4784359
132911530	132911552	9	+	27760321	HT1080	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	-0.15605890522450605	[460,359]	[162,128]	0	hSpCas9	negative selection	4784360
132912318	132912340	9	+	27760321	HT1080	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.08950764071023343	[309,241]	[179,47]	0	hSpCas9	negative selection	4784361
132921393	132921415	9	-	27760321	HT1080	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-2.893192736435622	[240,187]	[0,22]	-7	hSpCas9	negative selection	4784362
132923461	132923483	9	-	27760321	HT1080	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-1.9519651131892963	[255,199]	[22,23]	-6	hSpCas9	negative selection	4784363
132911464	132911486	9	+	27760321	HT29	viability after 7 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-0.3067889474392269	[747,583]	[842,647,608]	-4	hSpCas9	negative selection	4867822
132911530	132911552	9	+	27760321	HT29	viability after 7 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.22232653497309846	[460,359]	[530,456,838]	3	hSpCas9	negative selection	4867823
132912318	132912340	9	+	27760321	HT29	viability after 7 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.03349492886281724	[309,241]	[448,374,279]	0	hSpCas9	negative selection	4867824
132921393	132921415	9	-	27760321	HT29	viability after 7 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-1.0900238216948066	[240,187]	[193,148,56]	-8	hSpCas9	negative selection	4867825
132923461	132923483	9	-	27760321	HT29	viability after 7 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-0.47612340561467636	[255,199]	[258,205,174]	-6	hSpCas9	negative selection	4867826
132911464	132911486	9	+	27760321	HT29	viability after 25 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.47396069748119407	[747,583]	[1153,717,1318]	5	hSpCas9	negative selection	4951285
132911530	132911552	9	+	27760321	HT29	viability after 25 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.6454466584130762	[460,359]	[511,816,902]	7	hSpCas9	negative selection	4951286
132912318	132912340	9	+	27760321	HT29	viability after 25 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.8831968116783337	[309,241]	[541,691,504]	8	hSpCas9	negative selection	4951287
132921393	132921415	9	-	27760321	HT29	viability after 25 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	0.16948388868645348	[240,187]	[212,165,471]	1	hSpCas9	negative selection	4951288
132923461	132923483	9	-	27760321	HT29	viability after 25 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.4273531107585624	[255,199]	[225,486,344]	4	hSpCas9	negative selection	4951289
132911464	132911486	9	+	27760321	HT29	viability after 22 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.34837402149315433	[747,583]	[807,668,1472]	3	hSpCas9	negative selection	5034748
132911530	132911552	9	+	27760321	HT29	viability after 22 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.9296408900941733	[460,359]	[872,905,933]	9	hSpCas9	negative selection	5034749
132912318	132912340	9	+	27760321	HT29	viability after 22 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.943177280035939	[309,241]	[495,593,754]	9	hSpCas9	negative selection	5034750
132921393	132921415	9	-	27760321	HT29	viability after 22 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	0.17227365393459004	[240,187]	[177,171,492]	1	hSpCas9	negative selection	5034751
132923461	132923483	9	-	27760321	HT29	viability after 22 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.345355072765889	[255,199]	[306,405,291]	3	hSpCas9	negative selection	5034752
132911464	132911486	9	+	27760321	HT29	viability after 19 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.3699734206576566	[747,583]	[1082,552,1313]	3	hSpCas9	negative selection	5118211
132911530	132911552	9	+	27760321	HT29	viability after 19 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.6259630544315089	[460,359]	[543,637,962]	6	hSpCas9	negative selection	5118212
132912318	132912340	9	+	27760321	HT29	viability after 19 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.3769370934062309	[309,241]	[358,451,412]	3	hSpCas9	negative selection	5118213
132921393	132921415	9	-	27760321	HT29	viability after 19 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	0.1150137916453462	[240,187]	[221,270,297]	1	hSpCas9	negative selection	5118214
132923461	132923483	9	-	27760321	HT29	viability after 19 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-0.16484279260157786	[255,199]	[145,185,351]	-1	hSpCas9	negative selection	5118215
132911464	132911486	9	+	27760321	HT29	viability after 16 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.4330313811971296	[747,583]	[987,856,1174]	5	hSpCas9	negative selection	5201674
132911530	132911552	9	+	27760321	HT29	viability after 16 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.7323264498686175	[460,359]	[971,673,664]	8	hSpCas9	negative selection	5201675
132912318	132912340	9	+	27760321	HT29	viability after 16 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.8613615439005422	[309,241]	[664,397,633]	8	hSpCas9	negative selection	5201676
132921393	132921415	9	-	27760321	HT29	viability after 16 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-0.06988970920801851	[240,187]	[215,291,174]	-1	hSpCas9	negative selection	5201677
132923461	132923483	9	-	27760321	HT29	viability after 16 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.5354844598993236	[255,199]	[307,268,528]	6	hSpCas9	negative selection	5201678
132911464	132911486	9	+	27760321	HT29	viability after 13 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.3988862727190685	[747,583]	[782,1023,1235]	5	hSpCas9	negative selection	5285137
132911530	132911552	9	+	27760321	HT29	viability after 13 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.9450748317068096	[460,359]	[1230,809,720]	9	hSpCas9	negative selection	5285138
132912318	132912340	9	+	27760321	HT29	viability after 13 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.706033370158331	[309,241]	[462,631,474]	8	hSpCas9	negative selection	5285139
132921393	132921415	9	-	27760321	HT29	viability after 13 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	0.017325820364814892	[240,187]	[392,175,189]	0	hSpCas9	negative selection	5285140
132923461	132923483	9	-	27760321	HT29	viability after 13 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.27845687987637047	[255,199]	[316,384,263]	3	hSpCas9	negative selection	5285141
132911464	132911486	9	+	27760321	HT29	viability after 10 days	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	0.3423777796138141	[747,583]	[931,914,1305]	4	hSpCas9	negative selection	5368600
132911530	132911552	9	+	27760321	HT29	viability after 10 days	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	0.5090207988680941	[460,359]	[860,748,581]	7	hSpCas9	negative selection	5368601
132912318	132912340	9	+	27760321	HT29	viability after 10 days	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.5915742261028911	[309,241]	[524,320,701]	7	hSpCas9	negative selection	5368602
132921393	132921415	9	-	27760321	HT29	viability after 10 days	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-0.22123596980583216	[240,187]	[129,210,344]	-3	hSpCas9	negative selection	5368603
132923461	132923483	9	-	27760321	HT29	viability after 10 days	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.5711821178993737	[255,199]	[366,430,469]	7	hSpCas9	negative selection	5368604
132911464	132911486	9	+	27760321	MOLM13	viability	CAGTTATCAGCCGTGTCGATGG	TSC1	ENSG00000165699	-0.49440059998002367	[797,747]	[110,478]	-3	hSpCas9	negative selection	5452063
132911530	132911552	9	+	27760321	MOLM13	viability	TCAGCCGAGACGTGGAGTAAGG	TSC1	ENSG00000165699	-0.0036616350145054766	[581,460]	[255,321]	0	hSpCas9	negative selection	5452064
132912318	132912340	9	+	27760321	MOLM13	viability	TGACATCGGCTGAACGATGAGG	TSC1	ENSG00000165699	0.06968961575037716	[415,309]	[117,293]	0	hSpCas9	negative selection	5452065
132921393	132921415	9	-	27760321	MOLM13	viability	TTCATCCGGAATTAGTGACTGG	TSC1	ENSG00000165699	-2.5625902738342905	[257,240]	[25,21]	-8	hSpCas9	negative selection	5452066
132923461	132923483	9	-	27760321	MOLM13	viability	ACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	-2.3221046115501145	[264,255]	[9,45]	-8	hSpCas9	negative selection	5452067
132944150	132944173	9	-	27661255	K562	viability	GTAGAGACGCTTGGCGGGAGGGG	TSC1	ENSG00000165699	0.01684029226073336	[1181,1144]	[942,938]	0	dCas9-KRAB	negative selection	5520105
132944542	132944565	9	-	27661255	K562	viability	GCTGAGGGGGAGGAGACGGTGGG	TSC1	ENSG00000165699	0.2613737318616235	[759,1008]	[915,779]	8	dCas9-KRAB	negative selection	5520106
132944599	132944622	9	-	27661255	K562	viability	GTGCTGTACGTCCAAGATGGCGG	TSC1	ENSG00000165699	0.13573633180479033	[1009,1129]	[1029,857]	5	dCas9-KRAB	negative selection	5520107
132944602	132944625	9	-	27661255	K562	viability	GAGGTGCTGTACGTCCAAGATGG	TSC1	ENSG00000165699	0.20905779316130357	[1725,1779]	[1715,1533]	7	dCas9-KRAB	negative selection	5520108
132921950	132921973	9	+	27260156	BXPC3	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.06127046356303134	[831]	[703,917,776,952]	-1	hSpCas9	negative selection	5577890
132921915	132921938	9	+	27260156	BXPC3	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.17878647051283444	[533]	[487,362,573,562]	-4	hSpCas9	negative selection	5577891
132921406	132921429	9	-	27260156	BXPC3	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.13148121292282555	[293]	[255,209,293,379]	-3	hSpCas9	negative selection	5577892
132925670	132925693	9	-	27260156	BXPC3	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.26809309372416945	[513]	[652,521,565,876]	6	hSpCas9	negative selection	5642139
132921361	132921384	9	+	27260156	BXPC3	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5572698990147262	[375]	[577,544,589,601]	9	hSpCas9	negative selection	5642140
132925715	132925738	9	+	27260156	BXPC3	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.5686965507833838	[749]	[569,419,580,544]	-8	hSpCas9	negative selection	5642141
132921950	132921973	9	+	27260156	A673	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.2982885862056792	[831]	[1402,1146,1291,1082]	7	hSpCas9	negative selection	5699141
132921915	132921938	9	+	27260156	A673	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.07318927248704582	[533]	[547,521,598,771]	-2	hSpCas9	negative selection	5699142
132921406	132921429	9	-	27260156	A673	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.2808276233287465	[293]	[385,367,430,531]	6	hSpCas9	negative selection	5699143
132925670	132925693	9	-	27260156	A673	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.7612884750607949	[513]	[1339,816,953,1115]	9	hSpCas9	negative selection	5763390
132921361	132921384	9	+	27260156	A673	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5254429799646033	[375]	[804,523,630,659]	9	hSpCas9	negative selection	5763391
132925715	132925738	9	+	27260156	A673	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.225777193097644	[749]	[1450,966,933,898]	5	hSpCas9	negative selection	5763392
132921950	132921973	9	+	27260156	A375	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.10496309177341889	[831]	[1163,1277,864,917]	1	hSpCas9	negative selection	5820392
132921915	132921938	9	+	27260156	A375	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.6668405501905601	[533]	[327,604,402,276]	-7	hSpCas9	negative selection	5820393
132921406	132921429	9	-	27260156	A375	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.6415349127446168	[293]	[607,568,628,360]	8	hSpCas9	negative selection	5820394
132925670	132925693	9	-	27260156	A375	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.873426578994261	[513]	[1080,1286,1239,843]	9	hSpCas9	negative selection	5884641
132921361	132921384	9	+	27260156	A375	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.6490204117148625	[375]	[788,891,568,547]	8	hSpCas9	negative selection	5884642
132925715	132925738	9	+	27260156	A375	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.6728819798160531	[749]	[516,515,535,613]	-7	hSpCas9	negative selection	5884643
132921950	132921973	9	+	27260156	COLO741	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.1957676980812061	[831]	[1009,1001,787]	-4	hSpCas9	negative selection	5941643
132921915	132921938	9	+	27260156	COLO741	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.44370810459005783	[533]	[579,493,440]	-7	hSpCas9	negative selection	5941644
132921406	132921429	9	-	27260156	COLO741	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.20872972874546242	[293]	[610,395,317]	4	hSpCas9	negative selection	5941645
132925670	132925693	9	-	27260156	COLO741	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.3949580262956674	[513]	[1014,788,801]	7	hSpCas9	negative selection	6005892
132921361	132921384	9	+	27260156	COLO741	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.43939879374872437	[375]	[776,627,564]	8	hSpCas9	negative selection	6005893
132925715	132925738	9	+	27260156	COLO741	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.4700155455978612	[749]	[781,768,541]	-7	hSpCas9	negative selection	6005894
132921950	132921973	9	+	27260156	CAL120	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.3018660980586949	[831]	[1536,1357,977]	4	hSpCas9	negative selection	6062894
132921915	132921938	9	+	27260156	CAL120	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.18498706682425917	[533]	[468,515,747]	-3	hSpCas9	negative selection	6062895
132921406	132921429	9	-	27260156	CAL120	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.8708740415704257	[293]	[484,925,569]	9	hSpCas9	negative selection	6062896
132925670	132925693	9	-	27260156	CAL120	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.6456220380096476	[513]	[1088,1050,876]	8	hSpCas9	negative selection	6127143
132921361	132921384	9	+	27260156	CAL120	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.9565599450952372	[375]	[1125,862,769]	9	hSpCas9	negative selection	6127144
132925715	132925738	9	+	27260156	CAL120	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.28171925849449264	[749]	[1091,1238,1066]	4	hSpCas9	negative selection	6127145
132921950	132921973	9	+	27260156	CADOES1	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.9418397581850062	[831]	[1414,1451,1463,1619]	9	hSpCas9	negative selection	6184145
132921915	132921938	9	+	27260156	CADOES1	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	1.0465215835560726	[533]	[671,1732,747,949]	9	hSpCas9	negative selection	6184146
132921406	132921429	9	-	27260156	CADOES1	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.9295720215621637	[293]	[618,375,635,448]	9	hSpCas9	negative selection	6184147
132925670	132925693	9	-	27260156	CADOES1	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	1.3513281598526437	[513]	[1171,1155,996,1566]	9	hSpCas9	negative selection	6248394
132921361	132921384	9	+	27260156	CADOES1	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	1.0921023474722595	[375]	[1072,593,744,561]	9	hSpCas9	negative selection	6248395
132925715	132925738	9	+	27260156	CADOES1	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.6489887049729304	[749]	[1138,726,1343,1166]	9	hSpCas9	negative selection	6248396
132921950	132921973	9	+	27260156	EWS502	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.26527086601175354	[831]	[1058,1176,1055,925]	4	hSpCas9	negative selection	6305396
132921915	132921938	9	+	27260156	EWS502	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.33482839733188297	[533]	[832,619,742,638]	6	hSpCas9	negative selection	6305397
132921406	132921429	9	-	27260156	EWS502	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.5131278477069621	[293]	[445,434,501,389]	8	hSpCas9	negative selection	6305398
132925670	132925693	9	-	27260156	EWS502	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.549324830472697	[513]	[758,693,872,872]	8	hSpCas9	negative selection	6369645
132921361	132921384	9	+	27260156	EWS502	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5625095450361353	[375]	[464,644,842,399]	8	hSpCas9	negative selection	6369646
132925715	132925738	9	+	27260156	EWS502	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.5242533732418624	[749]	[1138,989,1050,1409]	8	hSpCas9	negative selection	6369647
132921950	132921973	9	+	27260156	EW8	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.16755876130379244	[831]	[780,575,484,596]	-3	hSpCas9	negative selection	6426647
132921915	132921938	9	+	27260156	EW8	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.17830917009915118	[533]	[447,736,432,345]	3	hSpCas9	negative selection	6426648
132921406	132921429	9	-	27260156	EW8	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.2570672927955989	[293]	[153,174,208,251]	-5	hSpCas9	negative selection	6426649
132925670	132925693	9	-	27260156	EW8	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.36685375518284175	[513]	[619,499,465,581]	6	hSpCas9	negative selection	6490896
132921361	132921384	9	+	27260156	EW8	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.33549154369832435	[375]	[497,244,363,444]	6	hSpCas9	negative selection	6490897
132925715	132925738	9	+	27260156	EW8	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.4576884599032023	[749]	[384,491,399,492]	-7	hSpCas9	negative selection	6490898
132921950	132921973	9	+	27260156	CORL105	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.525496662569321	[831]	[866,633,717,501]	-7	hSpCas9	negative selection	6547898
132921915	132921938	9	+	27260156	CORL105	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-1.0382778419511256	[533]	[196,304,489,250]	-9	hSpCas9	negative selection	6547899
132921406	132921429	9	-	27260156	CORL105	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.3489738238658737	[293]	[418,346,675,349]	6	hSpCas9	negative selection	6547900
132925670	132925693	9	-	27260156	CORL105	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.3073939440524428	[513]	[651,687,1034,646]	6	hSpCas9	negative selection	6612147
132921361	132921384	9	+	27260156	CORL105	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.09714585121365946	[375]	[385,404,689,434]	1	hSpCas9	negative selection	6612148
132925715	132925738	9	+	27260156	CORL105	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.94615844333374	[749]	[531,497,474,322]	-9	hSpCas9	negative selection	6612149
132921950	132921973	9	+	27260156	HS294T	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.5287379925092808	[831]	[596,357,413,478]	7	hSpCas9	negative selection	6669149
132921915	132921938	9	+	27260156	HS294T	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.5835444086702576	[533]	[395,223,256,362]	7	hSpCas9	negative selection	6669150
132921406	132921429	9	-	27260156	HS294T	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.424465915804678	[293]	[124,161,152,175]	6	hSpCas9	negative selection	6669151
132925670	132925693	9	-	27260156	HS294T	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.3980074300677315	[513]	[160,270,302,332]	5	hSpCas9	negative selection	6733398
132921361	132921384	9	+	27260156	HS294T	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	1.0727508343344765	[375]	[442,285,206,266]	9	hSpCas9	negative selection	6733399
132925715	132925738	9	+	27260156	HS294T	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.388341058964607	[749]	[200,450,289,631]	5	hSpCas9	negative selection	6733400
132921950	132921973	9	+	27260156	HCC44	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.022573613878736243	[831]	[987,728,1124,923]	0	hSpCas9	negative selection	6790400
132921915	132921938	9	+	27260156	HCC44	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.003132056603596556	[533]	[804,363,595,698]	0	hSpCas9	negative selection	6790401
132921406	132921429	9	-	27260156	HCC44	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.07123042491166487	[293]	[285,350,455,314]	1	hSpCas9	negative selection	6790402
132925670	132925693	9	-	27260156	HCC44	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.7081744515045565	[513]	[861,966,1225,778]	9	hSpCas9	negative selection	6854649
132921361	132921384	9	+	27260156	HCC44	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.6171540415005332	[375]	[857,377,763,679]	8	hSpCas9	negative selection	6854650
132925715	132925738	9	+	27260156	HCC44	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.27066324272960907	[749]	[731,763,642,652]	-4	hSpCas9	negative selection	6854651
132921950	132921973	9	+	27260156	G402	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.040167193765209164	[831]	[1229,982,1387,614]	0	hSpCas9	negative selection	6911651
132921915	132921938	9	+	27260156	G402	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.02978403428883475	[533]	[547,725,382,873]	0	hSpCas9	negative selection	6911652
132921406	132921429	9	-	27260156	G402	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.657536403552989	[293]	[169,483,865,673]	7	hSpCas9	negative selection	6911653
132925670	132925693	9	-	27260156	G402	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	1.486966457290411	[513]	[1681,827,2456,1981]	9	hSpCas9	negative selection	6975900
132921361	132921384	9	+	27260156	G402	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	1.0370055740847517	[375]	[1453,462,625,1249]	9	hSpCas9	negative selection	6975901
132925715	132925738	9	+	27260156	G402	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.11664384313716913	[749]	[943,429,755,1214]	-1	hSpCas9	negative selection	6975902
132921950	132921973	9	+	27260156	L33	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.16000096750028414	[831]	[911,401,681,742]	3	hSpCas9	negative selection	7032902
132921915	132921938	9	+	27260156	L33	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.45767381218304815	[533]	[933,298,381,656]	8	hSpCas9	negative selection	7032903
132921406	132921429	9	-	27260156	L33	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.4013825539594708	[293]	[374,146,245,427]	8	hSpCas9	negative selection	7032904
132925670	132925693	9	-	27260156	L33	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.28891911927452624	[513]	[600,317,373,540]	6	hSpCas9	negative selection	7097151
132921361	132921384	9	+	27260156	L33	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.3760376151628348	[375]	[508,171,388,404]	7	hSpCas9	negative selection	7097152
132925715	132925738	9	+	27260156	L33	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.0471270876320653	[749]	[793,285,445,895]	1	hSpCas9	negative selection	7097153
132921950	132921973	9	+	27260156	K562	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.05649168643084945	[831]	[805,375,1149,517]	0	hSpCas9	negative selection	7154153
132921915	132921938	9	+	27260156	K562	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.5993075722573681	[533]	[185,276,342,418]	-6	hSpCas9	negative selection	7154154
132921406	132921429	9	-	27260156	K562	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.850054798636773	[293]	[282,330,870,381]	9	hSpCas9	negative selection	7154155
132925670	132925693	9	-	27260156	K562	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.34970508729116295	[513]	[462,808,444,604]	4	hSpCas9	negative selection	7218402
132921361	132921384	9	+	27260156	K562	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5229562311533056	[375]	[429,797,263,440]	6	hSpCas9	negative selection	7218403
132925715	132925738	9	+	27260156	K562	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.1462305012662313	[749]	[333,347,348,188]	-8	hSpCas9	negative selection	7218404
132921950	132921973	9	+	27260156	HT29	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.13821668509718865	[831]	[990,882,1024,788]	-3	hSpCas9	negative selection	7275404
132921915	132921938	9	+	27260156	HT29	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.7117899390438345	[533]	[369,371,409,422]	-8	hSpCas9	negative selection	7275405
132921406	132921429	9	-	27260156	HT29	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.06064499176431892	[293]	[422,309,311,433]	1	hSpCas9	negative selection	7275406
132925670	132925693	9	-	27260156	HT29	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5013229695789561	[513]	[1137,887,863,685]	8	hSpCas9	negative selection	7339653
132921361	132921384	9	+	27260156	HT29	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.2862181567741765	[375]	[737,494,506,500]	5	hSpCas9	negative selection	7339654
132925715	132925738	9	+	27260156	HT29	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.5851071222677323	[749]	[591,846,534,486]	-7	hSpCas9	negative selection	7339655
132921950	132921973	9	+	27260156	MHHES1	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.9513738101178677	[831]	[1409,3057,1756,1202]	9	hSpCas9	negative selection	7396655
132921915	132921938	9	+	27260156	MHHES1	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	1.4746859419506255	[533]	[2036,1499,1340,1769]	9	hSpCas9	negative selection	7396656
132921406	132921429	9	-	27260156	MHHES1	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	1.0589889196710516	[293]	[998,616,319,806]	9	hSpCas9	negative selection	7396657
132925670	132925693	9	-	27260156	MHHES1	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	1.1435032526567888	[513]	[1322,1671,1192,1006]	9	hSpCas9	negative selection	7460904
132921361	132921384	9	+	27260156	MHHES1	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	1.61298877327269	[375]	[1107,933,1024,1882]	9	hSpCas9	negative selection	7460905
132925715	132925738	9	+	27260156	MHHES1	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	1.2854370999349678	[749]	[1953,2475,1881,1933]	9	hSpCas9	negative selection	7460906
132921950	132921973	9	+	27260156	MEWO	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.34612914439666054	[831]	[1307,953,767]	7	hSpCas9	negative selection	7517906
132921915	132921938	9	+	27260156	MEWO	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.28707163709387207	[533]	[596,643,584]	6	hSpCas9	negative selection	7517907
132921406	132921429	9	-	27260156	MEWO	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.1916232359093369	[293]	[332,306,305]	4	hSpCas9	negative selection	7517908
132925670	132925693	9	-	27260156	MEWO	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5297157135613093	[513]	[693,582,805]	9	hSpCas9	negative selection	7582155
132921361	132921384	9	+	27260156	MEWO	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.4797277786275608	[375]	[696,388,425]	8	hSpCas9	negative selection	7582156
132925715	132925738	9	+	27260156	MEWO	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.4406876799902495	[749]	[845,791,1198]	8	hSpCas9	negative selection	7582157
132921950	132921973	9	+	27260156	LNCAPCLONEFGC	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.5813561817767408	[831]	[499,388,522,612]	-7	hSpCas9	negative selection	7639157
132921915	132921938	9	+	27260156	LNCAPCLONEFGC	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-1.02043702057313	[533]	[178,234,237,302]	-8	hSpCas9	negative selection	7639158
132921406	132921429	9	-	27260156	LNCAPCLONEFGC	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.11299882672002792	[293]	[232,227,270,257]	-2	hSpCas9	negative selection	7639159
132925670	132925693	9	-	27260156	LNCAPCLONEFGC	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5430468163630124	[513]	[530,695,732,762]	8	hSpCas9	negative selection	7703406
132921361	132921384	9	+	27260156	LNCAPCLONEFGC	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.7547727464544915	[375]	[660,402,640,612]	9	hSpCas9	negative selection	7703407
132925715	132925738	9	+	27260156	LNCAPCLONEFGC	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.3489105424943442	[749]	[284,231,349,213]	-9	hSpCas9	negative selection	7703408
132921950	132921973	9	+	27260156	PANC0327	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-1.1001815696754524	[831]	[538,263,221,379]	-8	hSpCas9	negative selection	7760408
132921915	132921938	9	+	27260156	PANC0327	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-1.2604342052456654	[533]	[397,90,106,225]	-9	hSpCas9	negative selection	7760409
132921406	132921429	9	-	27260156	PANC0327	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.16733846371804273	[293]	[268,138,363,418]	2	hSpCas9	negative selection	7760410
132925670	132925693	9	-	27260156	PANC0327	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.12261359666042776	[513]	[465,424,537,565]	1	hSpCas9	negative selection	7824657
132921361	132921384	9	+	27260156	PANC0327	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.49226825946210273	[375]	[550,342,404,602]	7	hSpCas9	negative selection	7824658
132925715	132925738	9	+	27260156	PANC0327	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-2.2796409074039063	[749]	[112,158,136,134]	-9	hSpCas9	negative selection	7824659
132921950	132921973	9	+	27260156	NCIH2009	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.41063443975908953	[831]	[1530,1607,1489]	5	hSpCas9	negative selection	7881659
132921915	132921938	9	+	27260156	NCIH2009	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.3112863482556498	[533]	[656,757,395]	-4	hSpCas9	negative selection	7881660
132921406	132921429	9	-	27260156	NCIH2009	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.34738941583328675	[293]	[535,497,535]	5	hSpCas9	negative selection	7881661
132925670	132925693	9	-	27260156	NCIH2009	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5399039752798578	[513]	[1156,1032,962]	7	hSpCas9	negative selection	7945908
132921361	132921384	9	+	27260156	NCIH2009	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.32946819975955427	[375]	[694,609,681]	4	hSpCas9	negative selection	7945909
132925715	132925738	9	+	27260156	NCIH2009	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.5635220297369063	[749]	[923,730,512]	-6	hSpCas9	negative selection	7945910
132921950	132921973	9	+	27260156	NCIH1373	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-1.1166054485102361	[831]	[444,517,382,94]	-8	hSpCas9	negative selection	8002910
132921915	132921938	9	+	27260156	NCIH1373	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.9220184373738591	[533]	[211,390,405,57]	-7	hSpCas9	negative selection	8002911
132921406	132921429	9	-	27260156	NCIH1373	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.4816442066131064	[293]	[292,449,693,95]	5	hSpCas9	negative selection	8002912
132925670	132925693	9	-	27260156	NCIH1373	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.8335374841850125	[513]	[1046,798,1397,227]	8	hSpCas9	negative selection	8067159
132921361	132921384	9	+	27260156	NCIH1373	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.3866997592429634	[375]	[504,345,618,198]	4	hSpCas9	negative selection	8067160
132925715	132925738	9	+	27260156	NCIH1373	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.806692247606302	[749]	[404,126,215,65]	-9	hSpCas9	negative selection	8067161
132921950	132921973	9	+	27260156	PATU8902	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.4260135248880054	[831]	[1032,742,502,1307]	-4	hSpCas9	negative selection	8124161
132921915	132921938	9	+	27260156	PATU8902	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-1.5059969763690346	[533]	[219,201,215,440]	-8	hSpCas9	negative selection	8124162
132921406	132921429	9	-	27260156	PATU8902	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.27714768791759714	[293]	[669,495,444,364]	3	hSpCas9	negative selection	8124163
132925670	132925693	9	-	27260156	PATU8902	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.9478393366615003	[513]	[1126,2000,988,1518]	8	hSpCas9	negative selection	8188410
132921361	132921384	9	+	27260156	PATU8902	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.39586588357150587	[375]	[700,1085,364,682]	4	hSpCas9	negative selection	8188411
132925715	132925738	9	+	27260156	PATU8902	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.3404207733533464	[749]	[284,677,273,452]	-8	hSpCas9	negative selection	8188412
132921950	132921973	9	+	27260156	PANC1	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.456339556754664	[831]	[954,1585,792,735]	7	hSpCas9	negative selection	8245412
132921915	132921938	9	+	27260156	PANC1	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.07407263785486098	[533]	[279,666,549,470]	1	hSpCas9	negative selection	8245413
132921406	132921429	9	-	27260156	PANC1	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.5142022172067917	[293]	[253,622,406,230]	8	hSpCas9	negative selection	8245414
132925670	132925693	9	-	27260156	PANC1	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5280858781920825	[513]	[713,586,536,677]	8	hSpCas9	negative selection	8309661
132921361	132921384	9	+	27260156	PANC1	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.501677782487792	[375]	[514,444,445,417]	7	hSpCas9	negative selection	8309662
132925715	132925738	9	+	27260156	PANC1	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.24723252945298202	[749]	[780,894,743,667]	4	hSpCas9	negative selection	8309663
132921950	132921973	9	+	27260156	PANC0813	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.5151700697624175	[831]	[763,707,617,652]	-7	hSpCas9	negative selection	8366663
132921915	132921938	9	+	27260156	PANC0813	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.5813712176460601	[533]	[308,623,581,165]	-7	hSpCas9	negative selection	8366664
132921406	132921429	9	-	27260156	PANC0813	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.18688818169720312	[293]	[334,367,559,308]	3	hSpCas9	negative selection	8366665
132925670	132925693	9	-	27260156	PANC0813	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5288402704428694	[513]	[803,998,693,972]	8	hSpCas9	negative selection	8430912
132921361	132921384	9	+	27260156	PANC0813	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.3163066704553099	[375]	[671,633,522,389]	5	hSpCas9	negative selection	8430913
132925715	132925738	9	+	27260156	PANC0813	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-1.1300311344276852	[749]	[403,463,231,502]	-9	hSpCas9	negative selection	8430914
132921950	132921973	9	+	27260156	RDES	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.1267578804136944	[831]	[1103,867,924,1280]	2	hSpCas9	negative selection	8487914
132921915	132921938	9	+	27260156	RDES	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.4357773083980968	[533]	[612,782,1090,880]	7	hSpCas9	negative selection	8487915
132921406	132921429	9	-	27260156	RDES	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.26339012511344684	[293]	[254,277,450,724]	4	hSpCas9	negative selection	8487916
132925670	132925693	9	-	27260156	RDES	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.7081387247082918	[513]	[716,893,897,1459]	9	hSpCas9	negative selection	8552163
132921361	132921384	9	+	27260156	RDES	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5855311886638204	[375]	[511,472,797,881]	8	hSpCas9	negative selection	8552164
132925715	132925738	9	+	27260156	RDES	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.46276639229099326	[749]	[1031,1128,1402,1202]	7	hSpCas9	negative selection	8552165
132921950	132921973	9	+	27260156	PC3	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.24478796888932308	[831]	[813,813,1677,850]	5	hSpCas9	negative selection	8609165
132921915	132921938	9	+	27260156	PC3	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.0009866754747048234	[533]	[359,434,887,615]	0	hSpCas9	negative selection	8609166
132921406	132921429	9	-	27260156	PC3	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.04588940631545657	[293]	[255,279,343,250]	-1	hSpCas9	negative selection	8609167
132925670	132925693	9	-	27260156	PC3	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	-0.16957224504805873	[513]	[266,471,829,437]	-4	hSpCas9	negative selection	8673414
132921361	132921384	9	+	27260156	PC3	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.44513023707577654	[375]	[334,348,1280,407]	8	hSpCas9	negative selection	8673415
132925715	132925738	9	+	27260156	PC3	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.19366992797588367	[749]	[547,825,1391,916]	4	hSpCas9	negative selection	8673416
132921950	132921973	9	+	27260156	PATU8988T	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.904395771305724	[831]	[1391,1542,1791,1272]	9	hSpCas9	negative selection	8730416
132921915	132921938	9	+	27260156	PATU8988T	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	1.0463273333736482	[533]	[782,1091,816,1620]	9	hSpCas9	negative selection	8730417
132921406	132921429	9	-	27260156	PATU8988T	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.5794979948851303	[293]	[571,501,231,399]	8	hSpCas9	negative selection	8730418
132925670	132925693	9	-	27260156	PATU8988T	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5233074233996411	[513]	[591,564,710,995]	8	hSpCas9	negative selection	8794665
132921361	132921384	9	+	27260156	PATU8988T	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.6119586846778187	[375]	[503,562,619,531]	8	hSpCas9	negative selection	8794666
132925715	132925738	9	+	27260156	PATU8988T	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	1.006939310182741	[749]	[1131,1586,1364,1780]	9	hSpCas9	negative selection	8794667
132921950	132921973	9	+	27260156	T47D	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.1748338304893846	[831]	[1108,987,1130,1158]	4	hSpCas9	negative selection	8851667
132921915	132921938	9	+	27260156	T47D	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.15514435029660226	[533]	[567,698,742,760]	3	hSpCas9	negative selection	8851668
132921406	132921429	9	-	27260156	T47D	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.21860503675109633	[293]	[460,363,306,468]	4	hSpCas9	negative selection	8851669
132925670	132925693	9	-	27260156	T47D	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.4526420475652739	[513]	[894,772,762,852]	8	hSpCas9	negative selection	8915916
132921361	132921384	9	+	27260156	T47D	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.48449271044079545	[375]	[508,610,640,691]	8	hSpCas9	negative selection	8915917
132925715	132925738	9	+	27260156	T47D	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.0837708418151526	[749]	[863,843,954,1050]	1	hSpCas9	negative selection	8915918
132921950	132921973	9	+	27260156	SU8686	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	-0.3273984621967223	[831]	[564,574,713,819]	-5	hSpCas9	negative selection	8972918
132921915	132921938	9	+	27260156	SU8686	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.46533565987140013	[533]	[443,360,359,356]	-6	hSpCas9	negative selection	8972919
132921406	132921429	9	-	27260156	SU8686	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.21457140891984794	[293]	[312,270,435,345]	3	hSpCas9	negative selection	8972920
132925670	132925693	9	-	27260156	SU8686	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.6147172832779928	[513]	[724,629,936,867]	8	hSpCas9	negative selection	9037167
132921361	132921384	9	+	27260156	SU8686	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.22807818633324722	[375]	[423,378,460,498]	4	hSpCas9	negative selection	9037168
132925715	132925738	9	+	27260156	SU8686	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.9210195220551145	[749]	[470,359,372,351]	-8	hSpCas9	negative selection	9037169
132921950	132921973	9	+	27260156	SKES1	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.197733699671107	[831]	[1121,1004,927,791]	4	hSpCas9	negative selection	9094169
132921915	132921938	9	+	27260156	SKES1	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.02056780537022096	[533]	[491,647,562,414]	0	hSpCas9	negative selection	9094170
132921406	132921429	9	-	27260156	SKES1	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	-0.0023876145741509314	[293]	[279,300,290,294]	0	hSpCas9	negative selection	9094171
132925670	132925693	9	-	27260156	SKES1	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.44375457164737314	[513]	[755,631,661,728]	8	hSpCas9	negative selection	9158418
132921361	132921384	9	+	27260156	SKES1	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.3810554854353686	[375]	[626,618,327,419]	7	hSpCas9	negative selection	9158419
132925715	132925738	9	+	27260156	SKES1	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	-0.05127627612906638	[749]	[911,621,859,522]	-1	hSpCas9	negative selection	9158420
132921950	132921973	9	+	27260156	TOV112D	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.2574941841900915	[831]	[1227,1437,735,716]	5	hSpCas9	negative selection	9215420
132921915	132921938	9	+	27260156	TOV112D	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	-0.09670188525981079	[533]	[506,667,450,417]	-2	hSpCas9	negative selection	9215421
132921406	132921429	9	-	27260156	TOV112D	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.39384218913631047	[293]	[400,603,299,298]	7	hSpCas9	negative selection	9215422
132925670	132925693	9	-	27260156	TOV112D	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.5646952616678385	[513]	[679,722,786,835]	8	hSpCas9	negative selection	9279669
132921361	132921384	9	+	27260156	TOV112D	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.47189911430411047	[375]	[521,754,470,400]	8	hSpCas9	negative selection	9279670
132925715	132925738	9	+	27260156	TOV112D	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.10250430817941636	[749]	[718,1238,825,546]	2	hSpCas9	negative selection	9279671
132921950	132921973	9	+	27260156	TC71	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	0.4578305032383705	[831]	[1231,1228,1281,1149]	9	hSpCas9	negative selection	9336671
132921915	132921938	9	+	27260156	TC71	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	0.13808797107357143	[533]	[605,732,559,622]	3	hSpCas9	negative selection	9336672
132921406	132921429	9	-	27260156	TC71	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	0.051398625114059904	[293]	[454,312,253,280]	1	hSpCas9	negative selection	9336673
132925670	132925693	9	-	27260156	TC71	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	0.4901117865021098	[513]	[806,779,704,806]	9	hSpCas9	negative selection	9400920
132921361	132921384	9	+	27260156	TC71	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	0.5015725612152413	[375]	[495,520,593,678]	9	hSpCas9	negative selection	9400921
132925715	132925738	9	+	27260156	TC71	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	0.28331015526435854	[749]	[992,983,936,1001]	7	hSpCas9	negative selection	9400922
132921950	132921973	9	+	27260156	TC32	viability	CGAGATAGACTTCCGCCACGTGG	TSC1	ENSG00000165699	1.9347407007340776	[831]	[2769,1873,3991,3822]	9	hSpCas9	negative selection	9457922
132921915	132921938	9	+	27260156	TC32	viability	ATGAAAGAGTGCGTACACACTGG	TSC1	ENSG00000165699	2.49505036651976	[533]	[1815,2354,4254,3309]	9	hSpCas9	negative selection	9457923
132921406	132921429	9	-	27260156	TC32	viability	GGAGCATGTGCGAATTCATCCGG	TSC1	ENSG00000165699	1.6683200269676637	[293]	[782,1023,647,914]	9	hSpCas9	negative selection	9457924
132925670	132925693	9	-	27260156	TC32	viability	TTTATCCATCCTCTCGTTACTGG	TSC1	ENSG00000165699	1.4537701353978318	[513]	[1066,949,1843,1637]	9	hSpCas9	negative selection	9522171
132921361	132921384	9	+	27260156	TC32	viability	ACCTTCGAGGGTCCAGTTCATGG	TSC1	ENSG00000165699	2.1974787781650464	[375]	[1775,1320,2083,1357]	9	hSpCas9	negative selection	9522172
132925715	132925738	9	+	27260156	TC32	viability	ATTCGTTAATCCTGTCCAAGAGG	TSC1	ENSG00000165699	2.11149039352947	[749]	[2739,2459,2607,4452]	9	hSpCas9	negative selection	9522173
132910617	132910640	9	+	27869803	HPAFII	viability after 27 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.16356743368249194	[97]	[39,50,NaN]	-1	hSpCas9	negative selection	9604926
132911522	132911545	9	+	27869803	HPAFII	viability after 27 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.9029198043297616	[376]	[153,65,NaN]	-6	hSpCas9	negative selection	9604927
132921373	132921396	9	-	27869803	HPAFII	viability after 27 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.20015007579264166	[392]	[238,235,NaN]	1	hSpCas9	negative selection	9604928
132921926	132921949	9	+	27869803	HPAFII	viability after 27 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.3241241301068969	[564]	[191,274,NaN]	-2	hSpCas9	negative selection	9604929
132923461	132923484	9	-	27869803	HPAFII	viability after 27 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.0845740534980206	[445]	[625,389,NaN]	8	hSpCas9	negative selection	9604930
132925661	132925684	9	+	27869803	HPAFII	viability after 27 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-1.0572717193283447	[533]	[123,143,NaN]	-6	hSpCas9	negative selection	9604931
132910617	132910640	9	+	27869803	HPAFII	viability after 15 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.2560040786977327	[97]	[200,78,NaN]	3	hSpCas9	negative selection	9687375
132911522	132911545	9	+	27869803	HPAFII	viability after 15 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.35763050329998375	[376]	[478,214,NaN]	-4	hSpCas9	negative selection	9687376
132921373	132921396	9	-	27869803	HPAFII	viability after 15 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.047256804272703734	[392]	[491,356,NaN]	0	hSpCas9	negative selection	9687377
132921926	132921949	9	+	27869803	HPAFII	viability after 15 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.23798436562350955	[564]	[496,525,NaN]	-3	hSpCas9	negative selection	9687378
132923461	132923484	9	-	27869803	HPAFII	viability after 15 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.901979968574857	[445]	[1129,749,NaN]	8	hSpCas9	negative selection	9687379
132925661	132925684	9	+	27869803	HPAFII	viability after 15 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.9554493724063843	[533]	[319,280,NaN]	-7	hSpCas9	negative selection	9687380
132910617	132910640	9	+	27869803	ASPC1	viability after 36 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	-0.8893156798523829	[279]	[93,3,61]	-7	hSpCas9	negative selection	9769824
132911522	132911545	9	+	27869803	ASPC1	viability after 36 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	0.2013860558821382	[1082]	[487,524,320]	2	hSpCas9	negative selection	9769825
132921373	132921396	9	-	27869803	ASPC1	viability after 36 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	0.035455339259998775	[901]	[475,368,174]	0	hSpCas9	negative selection	9769826
132921926	132921949	9	+	27869803	ASPC1	viability after 36 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.2061988844289544	[1349]	[387,728,499]	2	hSpCas9	negative selection	9769827
132923461	132923484	9	-	27869803	ASPC1	viability after 36 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.793010383880032	[1608]	[1755,662,659]	7	hSpCas9	negative selection	9769828
132925661	132925684	9	+	27869803	ASPC1	viability after 36 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.2642289738633887	[1698]	[718,442,370]	-3	hSpCas9	negative selection	9769829
132910617	132910640	9	+	27869803	PATU8988S	viability after 35 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	1.0775793992609715	[205]	[218,130,NaN]	9	hSpCas9	negative selection	9852273
132911522	132911545	9	+	27869803	PATU8988S	viability after 35 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	1.2622750119017971	[1005]	[1141,800,NaN]	9	hSpCas9	negative selection	9852274
132921373	132921396	9	-	27869803	PATU8988S	viability after 35 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	1.5302037277422567	[833]	[816,1123,NaN]	9	hSpCas9	negative selection	9852275
132921926	132921949	9	+	27869803	PATU8988S	viability after 35 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	1.8841437971764001	[1056]	[1539,1602,NaN]	9	hSpCas9	negative selection	9852276
132923461	132923484	9	-	27869803	PATU8988S	viability after 35 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.2676881029132763	[1207]	[1138,1203,NaN]	9	hSpCas9	negative selection	9852277
132925661	132925684	9	+	27869803	PATU8988S	viability after 35 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	2.2982940334423487	[1373]	[2474,2969,NaN]	9	hSpCas9	negative selection	9852278
132910617	132910640	9	+	27869803	PATU8988S	viability after 31 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	1.0599029629584686	[205]	[205,126,NaN]	9	hSpCas9	negative selection	9934722
132911522	132911545	9	+	27869803	PATU8988S	viability after 31 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	1.171102048778291	[1005]	[963,825,NaN]	9	hSpCas9	negative selection	9934723
132921373	132921396	9	-	27869803	PATU8988S	viability after 31 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	1.304945178193501	[833]	[679,1001,NaN]	9	hSpCas9	negative selection	9934724
132921926	132921949	9	+	27869803	PATU8988S	viability after 31 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	1.6509179822541886	[1056]	[1140,1555,NaN]	9	hSpCas9	negative selection	9934725
132923461	132923484	9	-	27869803	PATU8988S	viability after 31 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.0257815565361863	[1207]	[857,1136,NaN]	9	hSpCas9	negative selection	9934726
132925661	132925684	9	+	27869803	PATU8988S	viability after 31 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	2.1766909422870873	[1373]	[1993,3091,NaN]	9	hSpCas9	negative selection	9934727
132910617	132910640	9	+	27869803	HPAFII	viability after 35 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.5335765312864961	[97]	[52,92,NaN]	3	hSpCas9	negative selection	10017171
132911522	132911545	9	+	27869803	HPAFII	viability after 35 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.7807865405040183	[376]	[167,46,NaN]	-4	hSpCas9	negative selection	10017172
132921373	132921396	9	-	27869803	HPAFII	viability after 35 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.34877618146158285	[392]	[143,169,NaN]	-2	hSpCas9	negative selection	10017173
132921926	132921949	9	+	27869803	HPAFII	viability after 35 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	0.06659359014338384	[564]	[85,539,NaN]	0	hSpCas9	negative selection	10017174
132923461	132923484	9	-	27869803	HPAFII	viability after 35 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	0.9027066741335569	[445]	[431,410,NaN]	6	hSpCas9	negative selection	10017175
132925661	132925684	9	+	27869803	HPAFII	viability after 35 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.9536891840247685	[533]	[116,164,NaN]	-5	hSpCas9	negative selection	10017176
132910617	132910640	9	+	27869803	HPAFII	viability after 31 days	TAGTCATCCGAATGACAGAGTGG	TSC1	ENSG00000165699	0.03884031797523724	[97]	[22,92,NaN]	0	hSpCas9	negative selection	10099620
132911522	132911545	9	+	27869803	HPAFII	viability after 31 days	TAACAACATCAGCCGAGACGTGG	TSC1	ENSG00000165699	-0.4031858261723326	[376]	[237,74,NaN]	-3	hSpCas9	negative selection	10099621
132921373	132921396	9	-	27869803	HPAFII	viability after 31 days	TGGATCCAAGGACCATGAACTGG	TSC1	ENSG00000165699	-0.03548003491408691	[392]	[174,258,NaN]	0	hSpCas9	negative selection	10099622
132921926	132921949	9	+	27869803	HPAFII	viability after 31 days	CGTACACACTGGCATGGAGATGG	TSC1	ENSG00000165699	-0.24256976649836337	[564]	[111,437,NaN]	-2	hSpCas9	negative selection	10099623
132923461	132923484	9	-	27869803	HPAFII	viability after 31 days	GACGTCGTTGTCCTCACAACAGG	TSC1	ENSG00000165699	1.0508304663679802	[445]	[530,504,NaN]	7	hSpCas9	negative selection	10099624
132925661	132925684	9	+	27869803	HPAFII	viability after 31 days	TGACATGACCCAGTAACGAGAGG	TSC1	ENSG00000165699	-0.8829019993378474	[533]	[106,222,NaN]	-5	hSpCas9	negative selection	10099625
132903699	132903722	9	+	28162770	P31FUJ	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.4511703021379432	[182]	[293]	5	hSpCas9	negative selection	10257841
132903650	132903673	9	-	28162770	P31FUJ	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	1.2918597860389638	[56]	[163]	9	hSpCas9	negative selection	10257842
132921920	132921943	9	+	28162770	P31FUJ	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.07876857574195784	[70]	[78]	-1	hSpCas9	negative selection	10257843
132911025	132911048	9	+	28162770	P31FUJ	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	1.0676816387339205	[243]	[600]	9	hSpCas9	negative selection	10257844
132910653	132910676	9	+	28162770	P31FUJ	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-1.139692800022897	[29]	[15]	-7	hSpCas9	negative selection	10257845
132906814	132906837	9	-	28162770	P31FUJ	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.21872930889814923	[282]	[386]	2	hSpCas9	negative selection	10257846
132906076	132906099	9	-	28162770	P31FUJ	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.9526238905681217	[287]	[654]	9	hSpCas9	negative selection	10257847
132905988	132906011	9	+	28162770	P31FUJ	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.6715326862903837	[451]	[845]	7	hSpCas9	negative selection	10257848
132905628	132905651	9	+	28162770	P31FUJ	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.14412491012335948	[910]	[1182]	1	hSpCas9	negative selection	10257849
132903790	132903813	9	+	28162770	P31FUJ	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.3993334165314001	[350]	[543]	4	hSpCas9	negative selection	10257850
132903699	132903722	9	+	28162770	TF1	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10427207
132903650	132903673	9	-	28162770	TF1	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10427208
132921920	132921943	9	+	28162770	TF1	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10427209
132911025	132911048	9	+	28162770	TF1	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10427210
132910653	132910676	9	+	28162770	TF1	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10427211
132906814	132906837	9	-	28162770	TF1	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10427212
132906076	132906099	9	-	28162770	TF1	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10427213
132905988	132906011	9	+	28162770	TF1	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	NaN	[NaN]	[224]	1	hSpCas9	negative selection	10427214
132905628	132905651	9	+	28162770	TF1	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	NaN	[NaN]	[294]	1	hSpCas9	negative selection	10427215
132903790	132903813	9	+	28162770	TF1	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10427216
132903699	132903722	9	+	28162770	SKM1	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.4495947213152122	[69]	[168]	4	hSpCas9	negative selection	10596573
132903650	132903673	9	-	28162770	SKM1	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	0.5472321116437138	[11]	[30]	5	hSpCas9	negative selection	10596574
132921920	132921943	9	+	28162770	SKM1	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.21194821633801908	[18]	[28]	-2	hSpCas9	negative selection	10596575
132911025	132911048	9	+	28162770	SKM1	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.6831739933246888	[98]	[108]	-5	hSpCas9	negative selection	10596576
132910653	132910676	9	+	28162770	SKM1	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-3.7288922936305235	[14]	[1]	-9	hSpCas9	negative selection	10596577
132906814	132906837	9	-	28162770	SKM1	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.9179354626754916	[96]	[323]	8	hSpCas9	negative selection	10596578
132906076	132906099	9	-	28162770	SKM1	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.06434152018242723	[65]	[121]	0	hSpCas9	negative selection	10596579
132905988	132906011	9	+	28162770	SKM1	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.0381406383950339	[91]	[166]	0	hSpCas9	negative selection	10596580
132905628	132905651	9	+	28162770	SKM1	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-0.02879726430743479	[160]	[278]	0	hSpCas9	negative selection	10596581
132903790	132903813	9	+	28162770	SKM1	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.6167400618481068	[82]	[224]	6	hSpCas9	negative selection	10596582
132903699	132903722	9	+	28162770	SKM1	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.4495947213152122	[69]	[168]	4	hSpCas9	negative selection	10765939
132903650	132903673	9	-	28162770	SKM1	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	0.5472321116437138	[11]	[30]	5	hSpCas9	negative selection	10765940
132921920	132921943	9	+	28162770	SKM1	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.21194821633801908	[18]	[28]	-2	hSpCas9	negative selection	10765941
132911025	132911048	9	+	28162770	SKM1	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.6831739933246888	[98]	[108]	-5	hSpCas9	negative selection	10765942
132910653	132910676	9	+	28162770	SKM1	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-3.7288922936305235	[14]	[1]	-9	hSpCas9	negative selection	10765943
132906814	132906837	9	-	28162770	SKM1	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.9179354626754916	[96]	[323]	8	hSpCas9	negative selection	10765944
132906076	132906099	9	-	28162770	SKM1	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.06434152018242723	[65]	[121]	0	hSpCas9	negative selection	10765945
132905988	132906011	9	+	28162770	SKM1	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.0381406383950339	[91]	[166]	0	hSpCas9	negative selection	10765946
132905628	132905651	9	+	28162770	SKM1	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-0.02879726430743479	[160]	[278]	0	hSpCas9	negative selection	10765947
132903790	132903813	9	+	28162770	SKM1	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.6167400618481068	[82]	[224]	6	hSpCas9	negative selection	10765948
132903699	132903722	9	+	28162770	PL21	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.9356397996510274	[196]	[163]	7	hSpCas9	negative selection	10935305
132903650	132903673	9	-	28162770	PL21	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	1.2803099631733033	[69]	[73]	9	hSpCas9	negative selection	10935306
132921920	132921943	9	+	28162770	PL21	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.36814414508520565	[85]	[28]	-3	hSpCas9	negative selection	10935307
132911025	132911048	9	+	28162770	PL21	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	0.4603340685381523	[338]	[202]	4	hSpCas9	negative selection	10935308
132910653	132910676	9	+	28162770	PL21	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-4.00931375113963	[36]	[0]	-9	hSpCas9	negative selection	10935309
132906814	132906837	9	-	28162770	PL21	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.45526882223776766	[304]	[181]	4	hSpCas9	negative selection	10935310
132906076	132906099	9	-	28162770	PL21	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.9536657215897153	[266]	[59]	-6	hSpCas9	negative selection	10935311
132905988	132906011	9	+	28162770	PL21	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.4779322906233176	[303]	[94]	-3	hSpCas9	negative selection	10935312
132905628	132905651	9	+	28162770	PL21	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.1799617325516898	[575]	[283]	1	hSpCas9	negative selection	10935313
132903790	132903813	9	+	28162770	PL21	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.8606531482176534	[247]	[195]	7	hSpCas9	negative selection	10935314
132903699	132903722	9	+	28162770	P31FUJ	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.4511703021379432	[182]	[293]	5	hSpCas9	negative selection	11104671
132903650	132903673	9	-	28162770	P31FUJ	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	1.2918597860389638	[56]	[163]	9	hSpCas9	negative selection	11104672
132921920	132921943	9	+	28162770	P31FUJ	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-0.07876857574195784	[70]	[78]	-1	hSpCas9	negative selection	11104673
132911025	132911048	9	+	28162770	P31FUJ	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	1.0676816387339205	[243]	[600]	9	hSpCas9	negative selection	11104674
132910653	132910676	9	+	28162770	P31FUJ	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-1.139692800022897	[29]	[15]	-7	hSpCas9	negative selection	11104675
132906814	132906837	9	-	28162770	P31FUJ	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.21872930889814923	[282]	[386]	2	hSpCas9	negative selection	11104676
132906076	132906099	9	-	28162770	P31FUJ	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.9526238905681217	[287]	[654]	9	hSpCas9	negative selection	11104677
132905988	132906011	9	+	28162770	P31FUJ	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.6715326862903837	[451]	[845]	7	hSpCas9	negative selection	11104678
132905628	132905651	9	+	28162770	P31FUJ	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.14412491012335948	[910]	[1182]	1	hSpCas9	negative selection	11104679
132903790	132903813	9	+	28162770	P31FUJ	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	0.3993334165314001	[350]	[543]	4	hSpCas9	negative selection	11104680
132903699	132903722	9	+	28162770	OCIAML5	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-2.1098643283316436	[109]	[45]	-8	hSpCas9	negative selection	11274037
132903650	132903673	9	-	28162770	OCIAML5	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-0.5719586516712618	[27]	[33]	-4	hSpCas9	negative selection	11274038
132921920	132921943	9	+	28162770	OCIAML5	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-1.6870073245935002	[65]	[36]	-7	hSpCas9	negative selection	11274039
132911025	132911048	9	+	28162770	OCIAML5	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-1.0491034179235506	[140]	[122]	-6	hSpCas9	negative selection	11274040
132910653	132910676	9	+	28162770	OCIAML5	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-2.5301384759766345	[15]	[4]	-8	hSpCas9	negative selection	11274041
132906814	132906837	9	-	28162770	OCIAML5	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.057858084834155	[189]	[356]	0	hSpCas9	negative selection	11274042
132906076	132906099	9	-	28162770	OCIAML5	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.9727480532864601	[161]	[148]	-6	hSpCas9	negative selection	11274043
132905988	132906011	9	+	28162770	OCIAML5	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-1.5281221303781303	[285]	[178]	-7	hSpCas9	negative selection	11274044
132905628	132905651	9	+	28162770	OCIAML5	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-1.546327714075965	[465]	[287]	-7	hSpCas9	negative selection	11274045
132903790	132903813	9	+	28162770	OCIAML5	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.6981910630861763	[230]	[256]	-4	hSpCas9	negative selection	11274046
132903699	132903722	9	+	28162770	EOL1	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-2.4775506720008114	[443]	[41]	-8	hSpCas9	negative selection	11443403
132903650	132903673	9	-	28162770	EOL1	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-0.7916592624288743	[68]	[20]	-5	hSpCas9	negative selection	11443404
132921920	132921943	9	+	28162770	EOL1	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	0.2507760038915223	[133]	[83]	2	hSpCas9	negative selection	11443405
132911025	132911048	9	+	28162770	EOL1	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	0.024675806058076954	[486]	[260]	0	hSpCas9	negative selection	11443406
132910653	132910676	9	+	28162770	EOL1	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-0.8275247149858798	[63]	[18]	-5	hSpCas9	negative selection	11443407
132906814	132906837	9	-	28162770	EOL1	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	-0.17902033897224479	[562]	[261]	-1	hSpCas9	negative selection	11443408
132906076	132906099	9	-	28162770	EOL1	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.17087179350814807	[249]	[116]	-1	hSpCas9	negative selection	11443409
132905988	132906011	9	+	28162770	EOL1	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.48532802259253033	[371]	[139]	-4	hSpCas9	negative selection	11443410
132905628	132905651	9	+	28162770	EOL1	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-0.7885435480304785	[858]	[261]	-5	hSpCas9	negative selection	11443411
132903790	132903813	9	+	28162770	EOL1	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.95571298415537	[415]	[112]	-6	hSpCas9	negative selection	11443412
132903699	132903722	9	+	28162770	MOLM13	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.3577064637941559	[271]	[251]	2	hSpCas9	negative selection	11612769
132903650	132903673	9	-	28162770	MOLM13	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-0.7224418305595708	[88]	[38]	-4	hSpCas9	negative selection	11612770
132921920	132921943	9	+	28162770	MOLM13	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-1.3531404774101021	[105]	[29]	-6	hSpCas9	negative selection	11612771
132911025	132911048	9	+	28162770	MOLM13	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.2844019438504637	[346]	[205]	-2	hSpCas9	negative selection	11612772
132910653	132910676	9	+	28162770	MOLM13	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-5.0556725745124345	[45]	[0]	-9	hSpCas9	negative selection	11612773
132906814	132906837	9	-	28162770	MOLM13	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	-0.10941954663314202	[469]	[314]	0	hSpCas9	negative selection	11612774
132906076	132906099	9	-	28162770	MOLM13	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-1.3616423313577002	[294]	[82]	-6	hSpCas9	negative selection	11612775
132905988	132906011	9	+	28162770	MOLM13	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.8867754997547832	[467]	[182]	-5	hSpCas9	negative selection	11612776
132905628	132905651	9	+	28162770	MOLM13	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-1.0337704724820158	[857]	[302]	-5	hSpCas9	negative selection	11612777
132903790	132903813	9	+	28162770	MOLM13	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.5321106184554211	[399]	[199]	-3	hSpCas9	negative selection	11612778
132903699	132903722	9	+	28162770	HEL	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-2.105281950674845	[261]	[38]	-8	hSpCas9	negative selection	11782135
132903650	132903673	9	-	28162770	HEL	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-2.231730285915784	[65]	[8]	-8	hSpCas9	negative selection	11782136
132921920	132921943	9	+	28162770	HEL	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	-1.2430901480803322	[84]	[22]	-6	hSpCas9	negative selection	11782137
132911025	132911048	9	+	28162770	HEL	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.879827131582932	[361]	[125]	-5	hSpCas9	negative selection	11782138
132910653	132910676	9	+	28162770	HEL	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-4.1646160900572475	[27]	[0]	-9	hSpCas9	negative selection	11782139
132906814	132906837	9	-	28162770	HEL	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.3960325960705634	[368]	[310]	3	hSpCas9	negative selection	11782140
132906076	132906099	9	-	28162770	HEL	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-1.2545015935744421	[297]	[79]	-6	hSpCas9	negative selection	11782141
132905988	132906011	9	+	28162770	HEL	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.373291277818592	[361]	[178]	-3	hSpCas9	negative selection	11782142
132905628	132905651	9	+	28162770	HEL	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-0.9316930012286297	[818]	[274]	-5	hSpCas9	negative selection	11782143
132903790	132903813	9	+	28162770	HEL	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-1.0996099588627524	[357]	[106]	-6	hSpCas9	negative selection	11782144
132903699	132903722	9	+	28162770	MV411	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-0.4306343543298623	[183]	[114]	-3	hSpCas9	negative selection	11951501
132903650	132903673	9	-	28162770	MV411	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-0.03267036840996007	[84]	[69]	0	hSpCas9	negative selection	11951502
132921920	132921943	9	+	28162770	MV411	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	0.4124967970532716	[65]	[73]	3	hSpCas9	negative selection	11951503
132911025	132911048	9	+	28162770	MV411	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	1.0557247475357543	[220]	[386]	8	hSpCas9	negative selection	11951504
132910653	132910676	9	+	28162770	MV411	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-4.074490544104587	[19]	[0]	-9	hSpCas9	negative selection	11951505
132906814	132906837	9	-	28162770	MV411	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.3360314740517639	[299]	[318]	3	hSpCas9	negative selection	11951506
132906076	132906099	9	-	28162770	MV411	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.21316764869802943	[212]	[207]	1	hSpCas9	negative selection	11951507
132905988	132906011	9	+	28162770	MV411	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.5897672990213889	[292]	[163]	-4	hSpCas9	negative selection	11951508
132905628	132905651	9	+	28162770	MV411	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.2408947049160035	[441]	[439]	2	hSpCas9	negative selection	11951509
132903790	132903813	9	+	28162770	MV411	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.3877981564196045	[291]	[187]	-3	hSpCas9	negative selection	11951510
132903699	132903722	9	+	28162770	MONOMAC1	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	0.288389980110688	[149]	[209]	3	hSpCas9	negative selection	12120867
132903650	132903673	9	-	28162770	MONOMAC1	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-1.8600018597819834	[37]	[11]	-8	hSpCas9	negative selection	12120868
132921920	132921943	9	+	28162770	MONOMAC1	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	0.6192511997680583	[45]	[80]	6	hSpCas9	negative selection	12120869
132911025	132911048	9	+	28162770	MONOMAC1	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	0.03782688608307938	[180]	[212]	0	hSpCas9	negative selection	12120870
132910653	132910676	9	+	28162770	MONOMAC1	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-1.5189649419469164	[14]	[5]	-8	hSpCas9	negative selection	12120871
132906814	132906837	9	-	28162770	MONOMAC1	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.4856516861234538	[194]	[312]	5	hSpCas9	negative selection	12120872
132906076	132906099	9	-	28162770	MONOMAC1	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.30854516227654405	[120]	[111]	-3	hSpCas9	negative selection	12120873
132905988	132906011	9	+	28162770	MONOMAC1	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-0.6284687845890662	[235]	[174]	-5	hSpCas9	negative selection	12120874
132905628	132905651	9	+	28162770	MONOMAC1	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.6357887625141687	[392]	[699]	6	hSpCas9	negative selection	12120875
132903790	132903813	9	+	28162770	MONOMAC1	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.6709680353919661	[174]	[125]	-5	hSpCas9	negative selection	12120876
132903699	132903722	9	+	28162770	OCIAML2	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-1.3682681076124834	[33]	[72]	-7	hSpCas9	negative selection	12290233
132903650	132903673	9	-	28162770	OCIAML2	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	-2.1811232080471763	[8]	[10]	-8	hSpCas9	negative selection	12290234
132921920	132921943	9	+	28162770	OCIAML2	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	0.09571699731164784	[12]	[76]	0	hSpCas9	negative selection	12290235
132911025	132911048	9	+	28162770	OCIAML2	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	-0.921736579228527	[53]	[157]	-6	hSpCas9	negative selection	12290236
132910653	132910676	9	+	28162770	OCIAML2	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-0.055592325963317535	[2]	[15]	0	hSpCas9	negative selection	12290237
132906814	132906837	9	-	28162770	OCIAML2	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	-0.30557057897166495	[65]	[295]	-2	hSpCas9	negative selection	12290238
132906076	132906099	9	-	28162770	OCIAML2	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	-0.4475462121291198	[30]	[125]	-4	hSpCas9	negative selection	12290239
132905988	132906011	9	+	28162770	OCIAML2	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	-1.1976113308357452	[47]	[115]	-7	hSpCas9	negative selection	12290240
132905628	132905651	9	+	28162770	OCIAML2	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	-1.7029925353335373	[120]	[205]	-7	hSpCas9	negative selection	12290241
132903790	132903813	9	+	28162770	OCIAML2	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	-0.9681294847129781	[47]	[135]	-6	hSpCas9	negative selection	12290242
132903699	132903722	9	+	28162770	OCIAML3	viability	GAGGAGCCGCCTGTTCCGGAGGG	TSC1	ENSG00000165699	-0.10215454399448837	[63]	[179]	-1	hSpCas9	negative selection	12459599
132903650	132903673	9	-	28162770	OCIAML3	viability	GGAGGAACATAATGCTGCCATGG	TSC1	ENSG00000165699	3.34010442401938	[20]	[641]	9	hSpCas9	negative selection	12459600
132921920	132921943	9	+	28162770	OCIAML3	viability	AGAGTGCGTACACACTGGCATGG	TSC1	ENSG00000165699	1.638653116466112	[19]	[187]	9	hSpCas9	negative selection	12459601
132911025	132911048	9	+	28162770	OCIAML3	viability	TAAGGGTGTGACAGATCAGGTGG	TSC1	ENSG00000165699	1.8274561281141137	[69]	[749]	9	hSpCas9	negative selection	12459602
132910653	132910676	9	+	28162770	OCIAML3	viability	GAGGTTGCTGGGGTTCCCAGAGG	TSC1	ENSG00000165699	-0.17897014104531994	[2]	[7]	-1	hSpCas9	negative selection	12459603
132906814	132906837	9	-	28162770	OCIAML3	viability	GAAGAGCCACCTGGCAGCAAAGG	TSC1	ENSG00000165699	0.2419164339302119	[99]	[356]	2	hSpCas9	negative selection	12459604
132906076	132906099	9	-	28162770	OCIAML3	viability	GCAGAGCCTGTGGTTCCTCGAGG	TSC1	ENSG00000165699	0.9420452599160465	[39]	[231]	7	hSpCas9	negative selection	12459605
132905988	132906011	9	+	28162770	OCIAML3	viability	GCTGGCGCCCTGAGAACTGGAGG	TSC1	ENSG00000165699	0.9771490608719626	[69]	[415]	8	hSpCas9	negative selection	12459606
132905628	132905651	9	+	28162770	OCIAML3	viability	GTCCAGCACTTCCATTGGGGAGG	TSC1	ENSG00000165699	0.7415953914602758	[188]	[953]	6	hSpCas9	negative selection	12459607
132903790	132903813	9	+	28162770	OCIAML3	viability	GTGCGGATCTCATCTGAAGGAGG	TSC1	ENSG00000165699	1.68092297502603	[77]	[754]	9	hSpCas9	negative selection	12459608