Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7249
• Symbol: TSC2
• Description: TSC complex subunit 2

DataSource: http://genomecrispr.dkfz.de/#!/results/TSC2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
2047816	2047839	16	+	26472758	Jiyoye	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	0.9858788917553473	[153]	[229]	6	hSpCas9	negative selection	111950
2047797	2047820	16	+	26472758	Jiyoye	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	0.552605821027437	[65]	[72]	4	hSpCas9	negative selection	111955
2047714	2047737	16	+	26472758	Jiyoye	viability	GCAGCCTCTCTTCTCCGGAGAGG	TSC2	ENSG00000103197	0.4588904180500287	[136]	[141]	3	hSpCas9	negative selection	111956
2084251	2084274	16	+	26472758	Jiyoye	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.41490682629828335	[319]	[180]	-3	hSpCas9	negative selection	173560
2079343	2079366	16	+	26472758	Jiyoye	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-0.3412858514981623	[125]	[74]	-2	hSpCas9	negative selection	173561
2060672	2060695	16	+	26472758	Jiyoye	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-0.007862117772970523	[31]	[23]	0	hSpCas9	negative selection	173562
2061963	2061986	16	+	26472758	Jiyoye	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.8185465635869477	[196]	[261]	6	hSpCas9	negative selection	173563
2064301	2064324	16	+	26472758	Jiyoye	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.7348436233665545	[127]	[57]	-5	hSpCas9	negative selection	173564
2065607	2065630	16	-	26472758	Jiyoye	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	0.5374317674572151	[126]	[138]	4	hSpCas9	negative selection	173565
2070547	2070570	16	-	26472758	Jiyoye	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-1.4756410791237875	[519]	[140]	-7	hSpCas9	negative selection	173566
2071885	2071908	16	-	26472758	Jiyoye	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-0.8384018272513741	[229]	[96]	-5	hSpCas9	negative selection	173567
2072321	2072344	16	-	26472758	Jiyoye	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.4101982963767217	[288]	[81]	-7	hSpCas9	negative selection	173568
2076125	2076148	16	+	26472758	Jiyoye	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.08758931024370464	[278]	[197]	0	hSpCas9	negative selection	173569
2047816	2047839	16	+	26472758	KBM7	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	1.0371414131400638	[723,498]	[594,569]	9	hSpCas9	negative selection	303068
2047797	2047820	16	+	26472758	KBM7	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	0.4695242245837301	[410,292]	[247,206]	5	hSpCas9	negative selection	303073
2047714	2047737	16	+	26472758	KBM7	viability	GCAGCCTCTCTTCTCCGGAGAGG	TSC2	ENSG00000103197	-0.04554916842315779	[688,422]	[326,177]	0	hSpCas9	negative selection	303074
2084251	2084274	16	+	26472758	KBM7	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	2.2246549395289	[659,293]	[1743,357]	9	hSpCas9	negative selection	364678
2079343	2079366	16	+	26472758	KBM7	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	1.553539509169723	[725,1510]	[2887,460]	9	hSpCas9	negative selection	364679
2060672	2060695	16	+	26472758	KBM7	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	3.1502583219943348	[245,208]	[1882,108]	9	hSpCas9	negative selection	364680
2061963	2061986	16	+	26472758	KBM7	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	1.9075011537409245	[1182,769]	[3182,361]	9	hSpCas9	negative selection	364681
2064301	2064324	16	+	26472758	KBM7	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	0.9571421311505339	[423,235]	[417,182]	9	hSpCas9	negative selection	364682
2065607	2065630	16	-	26472758	KBM7	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	1.3658813592865877	[649,453]	[1187,187]	9	hSpCas9	negative selection	364683
2070547	2070570	16	-	26472758	KBM7	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	2.0746399642720514	[1023,1098]	[3257,1102]	9	hSpCas9	negative selection	364684
2071885	2071908	16	-	26472758	KBM7	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	1.48879202239725	[1008,1011]	[2205,565]	9	hSpCas9	negative selection	364685
2072321	2072344	16	-	26472758	KBM7	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	1.6072788439134267	[616,548]	[1291,424]	9	hSpCas9	negative selection	364686
2076125	2076148	16	+	26472758	KBM7	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	1.1238991439931307	[989,1028]	[1720,433]	9	hSpCas9	negative selection	364687
2047816	2047839	16	+	26472758	Raji	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	0.4612208782157058	[312]	[99]	4	hSpCas9	negative selection	494186
2047797	2047820	16	+	26472758	Raji	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	0.8468559851503804	[114]	[47]	7	hSpCas9	negative selection	494191
2047714	2047737	16	+	26472758	Raji	viability	GCAGCCTCTCTTCTCCGGAGAGG	TSC2	ENSG00000103197	0.0369942074822016	[230]	[54]	0	hSpCas9	negative selection	494192
2084251	2084274	16	+	26472758	Raji	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.5573061578182908	[278]	[43]	-4	hSpCas9	negative selection	555796
2079343	2079366	16	+	26472758	Raji	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-0.8394458056050629	[292]	[37]	-6	hSpCas9	negative selection	555797
2060672	2060695	16	+	26472758	Raji	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	0.1275614173112296	[70]	[17]	1	hSpCas9	negative selection	555798
2061963	2061986	16	+	26472758	Raji	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.28363708278670885	[555]	[105]	-2	hSpCas9	negative selection	555799
2064301	2064324	16	+	26472758	Raji	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.32145976343027494	[139]	[25]	-3	hSpCas9	negative selection	555800
2065607	2065630	16	-	26472758	Raji	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-0.6591857718375044	[278]	[40]	-5	hSpCas9	negative selection	555801
2070547	2070570	16	-	26472758	Raji	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.6184415011874063	[515]	[77]	-5	hSpCas9	negative selection	555802
2071885	2071908	16	-	26472758	Raji	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-1.4697168475745863	[548]	[45]	-7	hSpCas9	negative selection	555803
2072321	2072344	16	-	26472758	Raji	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.517107329534194	[332]	[26]	-8	hSpCas9	negative selection	555804
2076125	2076148	16	+	26472758	Raji	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-1.152642120587856	[478]	[49]	-7	hSpCas9	negative selection	555805
2047816	2047839	16	+	26472758	K562	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	0.998368501463532	[455]	[768]	8	hSpCas9	negative selection	685304
2047797	2047820	16	+	26472758	K562	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	0.8271634031377845	[216]	[324]	7	hSpCas9	negative selection	685309
2047714	2047737	16	+	26472758	K562	viability	GCAGCCTCTCTTCTCCGGAGAGG	TSC2	ENSG00000103197	0.6107118930938724	[300]	[387]	5	hSpCas9	negative selection	685310
2084251	2084274	16	+	26472758	K562	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	0.04260718375245118	[405]	[352]	0	hSpCas9	negative selection	746914
2079343	2079366	16	+	26472758	K562	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-0.6486660684170411	[519]	[279]	-4	hSpCas9	negative selection	746915
2060672	2060695	16	+	26472758	K562	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-0.6655711066009581	[232]	[123]	-4	hSpCas9	negative selection	746916
2061963	2061986	16	+	26472758	K562	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.11222411530157728	[867]	[791]	0	hSpCas9	negative selection	746917
2064301	2064324	16	+	26472758	K562	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.8590108619889587	[158]	[73]	-5	hSpCas9	negative selection	746918
2065607	2065630	16	-	26472758	K562	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-0.990718432390028	[378]	[160]	-5	hSpCas9	negative selection	746919
2070547	2070570	16	-	26472758	K562	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	0.4346918380392144	[836]	[954]	3	hSpCas9	negative selection	746920
2071885	2071908	16	-	26472758	K562	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.275064359287118	[882]	[153]	-7	hSpCas9	negative selection	746921
2072321	2072344	16	-	26472758	K562	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.3552402842614112	[443]	[292]	-2	hSpCas9	negative selection	746922
2076125	2076148	16	+	26472758	K562	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.3344124631849987	[586]	[392]	-2	hSpCas9	negative selection	746923
2048597	2048620	16	+	26627737	DLD1	viability	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.14123072921851587	[795]	[319,196,298]	1	hSpCas9	negative selection	793053
2053368	2053391	16	+	26627737	DLD1	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.613529965297939	[271]	[81,59,28]	-6	hSpCas9	negative selection	793054
2054386	2054409	16	+	26627737	DLD1	viability	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.6028063010501844	[871]	[476,423,350]	6	hSpCas9	negative selection	793055
2055489	2055512	16	+	26627737	DLD1	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.9302466048360745	[800]	[109,175,112]	-7	hSpCas9	negative selection	793056
2056222	2056245	16	-	26627737	DLD1	viability	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.7110731032856992	[559]	[484,151,225]	7	hSpCas9	negative selection	793057
2056721	2056744	16	-	26627737	DLD1	viability	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.2701852631538626	[1460]	[841,398,423]	2	hSpCas9	negative selection	793058
2048597	2048620	16	+	26627737	GBM cells	viability after 5 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.10696269145098375	[245]	[140,103]	-2	hSpCas9	negative selection	875368
2053368	2053391	16	+	26627737	GBM cells	viability after 5 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.21421902757931277	[130]	[78,83]	3	hSpCas9	negative selection	875369
2054386	2054409	16	+	26627737	GBM cells	viability after 5 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.22004687741845763	[725]	[454,451]	3	hSpCas9	negative selection	875370
2055489	2055512	16	+	26627737	GBM cells	viability after 5 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.25511975378673524	[157]	[62,78]	-4	hSpCas9	negative selection	875371
2056222	2056245	16	-	26627737	GBM cells	viability after 5 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.5599187422728431	[300]	[110,107]	-7	hSpCas9	negative selection	875372
2056721	2056744	16	-	26627737	GBM cells	viability after 5 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.3331449393978403	[503]	[359,320]	5	hSpCas9	negative selection	875373
2048597	2048620	16	+	26627737	GBM cells	viability after 13 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.04516032790115295	[245]	[162,101]	0	hSpCas9	negative selection	957683
2053368	2053391	16	+	26627737	GBM cells	viability after 13 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.2738343044461973	[130]	[91,80]	3	hSpCas9	negative selection	957684
2054386	2054409	16	+	26627737	GBM cells	viability after 13 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.06385069772575114	[725]	[510,330]	0	hSpCas9	negative selection	957685
2055489	2055512	16	+	26627737	GBM cells	viability after 13 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.019069430773715035	[157]	[98,76]	0	hSpCas9	negative selection	957686
2056222	2056245	16	-	26627737	GBM cells	viability after 13 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.19223879593845045	[300]	[164,124]	-2	hSpCas9	negative selection	957687
2056721	2056744	16	-	26627737	GBM cells	viability after 13 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.245633714655219	[503]	[287,183]	-3	hSpCas9	negative selection	957688
2048597	2048620	16	+	26627737	GBM cells	viability after 21 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.6215504327639655	[245]	[89,83]	-5	hSpCas9	negative selection	1039998
2053368	2053391	16	+	26627737	GBM cells	viability after 21 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.2597799560427432	[130]	[91,78]	2	hSpCas9	negative selection	1039999
2054386	2054409	16	+	26627737	GBM cells	viability after 21 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.22238105918105822	[725]	[347,328]	-2	hSpCas9	negative selection	1040000
2055489	2055512	16	+	26627737	GBM cells	viability after 21 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.22431135865458796	[157]	[73,72]	-2	hSpCas9	negative selection	1040001
2056222	2056245	16	-	26627737	GBM cells	viability after 21 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.7639224841879466	[300]	[100,91]	-6	hSpCas9	negative selection	1040002
2056721	2056744	16	-	26627737	GBM cells	viability after 21 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.49012739292440355	[503]	[207,182]	-4	hSpCas9	negative selection	1040003
2048597	2048620	16	+	26627737	RPE1	viability after 9 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	1.5170358188024844	[427]	[286,507]	8	hSpCas9	negative selection	1122313
2053368	2053391	16	+	26627737	RPE1	viability after 9 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.5729550808121757	[642]	[109,167]	-4	hSpCas9	negative selection	1122314
2054386	2054409	16	+	26627737	RPE1	viability after 9 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.9815218273535364	[2082]	[1081,1552]	6	hSpCas9	negative selection	1122315
2055489	2055512	16	+	26627737	RPE1	viability after 9 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.13517606025077594	[743]	[157,381]	1	hSpCas9	negative selection	1122316
2056222	2056245	16	-	26627737	RPE1	viability after 9 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.9603444853741401	[989]	[575,637]	6	hSpCas9	negative selection	1122317
2056721	2056744	16	-	26627737	RPE1	viability after 9 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	1.4908099062293916	[1541]	[958,1869]	8	hSpCas9	negative selection	1122318
2048597	2048620	16	+	26627737	RPE1	viability after 12 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	1.6277123145763557	[427]	[400,306]	8	hSpCas9	negative selection	1204628
2053368	2053391	16	+	26627737	RPE1	viability after 12 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.6508291248027904	[642]	[93,126]	-4	hSpCas9	negative selection	1204629
2054386	2054409	16	+	26627737	RPE1	viability after 12 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.0466969381181592	[2082]	[1039,1278]	6	hSpCas9	negative selection	1204630
2055489	2055512	16	+	26627737	RPE1	viability after 12 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.0742373328557606	[743]	[297,550]	6	hSpCas9	negative selection	1204631
2056222	2056245	16	-	26627737	RPE1	viability after 12 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.6245078546804606	[989]	[976,653]	8	hSpCas9	negative selection	1204632
2056721	2056744	16	-	26627737	RPE1	viability after 12 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	1.9322502984138898	[1541]	[1618,1540]	8	hSpCas9	negative selection	1204633
2048597	2048620	16	+	26627737	RPE1	viability after 15 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	1.5397598692257	[427]	[491,216]	7	hSpCas9	negative selection	1286943
2053368	2053391	16	+	26627737	RPE1	viability after 15 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.07483688634902591	[642]	[327,59]	0	hSpCas9	negative selection	1286944
2054386	2054409	16	+	26627737	RPE1	viability after 15 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.1247197628493228	[2082]	[1375,1196]	6	hSpCas9	negative selection	1286945
2055489	2055512	16	+	26627737	RPE1	viability after 15 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.005837879187843	[743]	[330,510]	6	hSpCas9	negative selection	1286946
2056222	2056245	16	-	26627737	RPE1	viability after 15 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.8269750100711455	[989]	[1128,862]	8	hSpCas9	negative selection	1286947
2056721	2056744	16	-	26627737	RPE1	viability after 15 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	2.535333736199337	[1541]	[2686,2375]	9	hSpCas9	negative selection	1286948
2048597	2048620	16	+	26627737	RPE1	viability after 18 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	1.6689921593887522	[427]	[200,544]	8	hSpCas9	negative selection	1369258
2053368	2053391	16	+	26627737	RPE1	viability after 18 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.27481551964866135	[642]	[178,242]	1	hSpCas9	negative selection	1369259
2054386	2054409	16	+	26627737	RPE1	viability after 18 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.1369717936213808	[2082]	[1155,1321]	6	hSpCas9	negative selection	1369260
2055489	2055512	16	+	26627737	RPE1	viability after 18 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.7670518638613213	[743]	[606,764]	8	hSpCas9	negative selection	1369261
2056222	2056245	16	-	26627737	RPE1	viability after 18 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	2.3407288422366195	[989]	[1509,1185]	9	hSpCas9	negative selection	1369262
2056721	2056744	16	-	26627737	RPE1	viability after 18 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	3.043233535721322	[1541]	[3251,3620]	9	hSpCas9	negative selection	1369263
2048597	2048620	16	+	26627737	HeLa	viability after 8 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	1.0124471812588434	[431]	[312,666,158]	7	hSpCas9	negative selection	1451573
2053368	2053391	16	+	26627737	HeLa	viability after 8 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	1.2859493623604594	[99]	[160,12,152]	8	hSpCas9	negative selection	1451574
2054386	2054409	16	+	26627737	HeLa	viability after 8 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.10867437239614408	[1124]	[559,469,361]	-1	hSpCas9	negative selection	1451575
2055489	2055512	16	+	26627737	HeLa	viability after 8 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.6508573349372466	[298]	[242,153,222]	5	hSpCas9	negative selection	1451576
2056222	2056245	16	-	26627737	HeLa	viability after 8 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.08713070643700882	[543]	[283,130,263]	-1	hSpCas9	negative selection	1451577
2056721	2056744	16	-	26627737	HeLa	viability after 8 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.49479746172519845	[850]	[382,424,712]	4	hSpCas9	negative selection	1451578
2048597	2048620	16	+	26627737	HeLa	viability after 12 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.8421509366215605	[431]	[242,224,499]	6	hSpCas9	negative selection	1533888
2053368	2053391	16	+	26627737	HeLa	viability after 12 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	1.450973351603872	[99]	[193,96,51]	8	hSpCas9	negative selection	1533889
2054386	2054409	16	+	26627737	HeLa	viability after 12 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.023681024034956755	[1124]	[405,424,542]	0	hSpCas9	negative selection	1533890
2055489	2055512	16	+	26627737	HeLa	viability after 12 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.3054742211955774	[298]	[40,73,185]	-3	hSpCas9	negative selection	1533891
2056222	2056245	16	-	26627737	HeLa	viability after 12 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.14498024241071655	[543]	[272,89,260]	-1	hSpCas9	negative selection	1533892
2056721	2056744	16	-	26627737	HeLa	viability after 12 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.174096671101152	[850]	[190,494,487]	1	hSpCas9	negative selection	1533893
2048597	2048620	16	+	26627737	HeLa	viability after 15 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.3788352567120291	[431]	[148,273,266]	3	hSpCas9	negative selection	1616203
2053368	2053391	16	+	26627737	HeLa	viability after 15 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	2.365402031626038	[99]	[243,197,184]	9	hSpCas9	negative selection	1616204
2054386	2054409	16	+	26627737	HeLa	viability after 15 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.22312110441445787	[1124]	[182,444,564]	-2	hSpCas9	negative selection	1616205
2055489	2055512	16	+	26627737	HeLa	viability after 15 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.8233622790332422	[298]	[25,86,95]	-6	hSpCas9	negative selection	1616206
2056222	2056245	16	-	26627737	HeLa	viability after 15 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.3740463857966548	[543]	[306,239,315]	3	hSpCas9	negative selection	1616207
2056721	2056744	16	-	26627737	HeLa	viability after 15 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.5361516195679388	[850]	[369,537,608]	4	hSpCas9	negative selection	1616208
2048597	2048620	16	+	26627737	HeLa	viability after 18 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.36947264410770786	[431]	[96,226,266]	3	hSpCas9	negative selection	1698518
2053368	2053391	16	+	26627737	HeLa	viability after 18 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	2.366549345498444	[99]	[167,158,184]	9	hSpCas9	negative selection	1698519
2054386	2054409	16	+	26627737	HeLa	viability after 18 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.2166409384429122	[1124]	[124,369,564]	-2	hSpCas9	negative selection	1698520
2055489	2055512	16	+	26627737	HeLa	viability after 18 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.8006382304015534	[298]	[17,73,95]	-6	hSpCas9	negative selection	1698521
2056222	2056245	16	-	26627737	HeLa	viability after 18 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.4143893505436978	[543]	[223,195,315]	3	hSpCas9	negative selection	1698522
2056721	2056744	16	-	26627737	HeLa	viability after 18 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.549319089439523	[850]	[251,451,608]	4	hSpCas9	negative selection	1698523
2048597	2048620	16	+	26627737	HCT116	viability after 6 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.7276426197758972	[1131]	[168,363]	4	hSpCas9	negative selection	1780833
2053368	2053391	16	+	26627737	HCT116	viability after 6 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.19436053003617748	[197]	[3,39]	-1	hSpCas9	negative selection	1780834
2054386	2054409	16	+	26627737	HCT116	viability after 6 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	-0.4921460294464144	[1794]	[315,136]	-3	hSpCas9	negative selection	1780835
2055489	2055512	16	+	26627737	HCT116	viability after 6 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.4089848020930713	[564]	[231,237]	7	hSpCas9	negative selection	1780836
2056222	2056245	16	-	26627737	HCT116	viability after 6 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.3680605748096141	[728]	[154,143]	2	hSpCas9	negative selection	1780837
2056721	2056744	16	-	26627737	HCT116	viability after 6 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.5200926467225813	[1461]	[346,319]	3	hSpCas9	negative selection	1780838
2048597	2048620	16	+	26627737	HCT116	viability after 8 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.24788508542251436	[358]	[272,247,184]	2	hSpCas9	negative selection	1863148
2053368	2053391	16	+	26627737	HCT116	viability after 8 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.4501117378854006	[213]	[200,121,160]	5	hSpCas9	negative selection	1863149
2054386	2054409	16	+	26627737	HCT116	viability after 8 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.4683864101919215	[602]	[532,432,414]	5	hSpCas9	negative selection	1863150
2055489	2055512	16	+	26627737	HCT116	viability after 8 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.1723743926386927	[158]	[171,144,273]	8	hSpCas9	negative selection	1863151
2056222	2056245	16	-	26627737	HCT116	viability after 8 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.294138612732837	[232]	[319,256,366]	9	hSpCas9	negative selection	1863152
2056721	2056744	16	-	26627737	HCT116	viability after 8 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.0956414193664945	[856]	[521,507,298]	-1	hSpCas9	negative selection	1863153
2048597	2048620	16	+	26627737	HCT116	viability after 9 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.5512763411018518	[1131]	[155,245]	-4	hSpCas9	negative selection	1945463
2053368	2053391	16	+	26627737	HCT116	viability after 9 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.9716921897490892	[197]	[120,89]	6	hSpCas9	negative selection	1945464
2054386	2054409	16	+	26627737	HCT116	viability after 9 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.12417305633918407	[1794]	[761,332]	1	hSpCas9	negative selection	1945465
2055489	2055512	16	+	26627737	HCT116	viability after 9 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.5091967913858823	[564]	[229,7]	-4	hSpCas9	negative selection	1945466
2056222	2056245	16	-	26627737	HCT116	viability after 9 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.020499791359352648	[728]	[311,96]	0	hSpCas9	negative selection	1945467
2056721	2056744	16	-	26627737	HCT116	viability after 9 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.5377104881004988	[1461]	[683,473]	4	hSpCas9	negative selection	1945468
2048597	2048620	16	+	26627737	HCT116	viability after 12 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.7319171928490034	[358]	[366,382,186]	6	hSpCas9	negative selection	2027778
2053368	2053391	16	+	26627737	HCT116	viability after 12 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.09412461494396374	[213]	[67,172,79]	-1	hSpCas9	negative selection	2027779
2054386	2054409	16	+	26627737	HCT116	viability after 12 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.26950148278533637	[602]	[451,266,417]	2	hSpCas9	negative selection	2027780
2055489	2055512	16	+	26627737	HCT116	viability after 12 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.4714610328024293	[158]	[216,172,304]	9	hSpCas9	negative selection	2027781
2056222	2056245	16	-	26627737	HCT116	viability after 12 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.282772419576512	[232]	[246,287,362]	8	hSpCas9	negative selection	2027782
2056721	2056744	16	-	26627737	HCT116	viability after 12 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.07828994576681136	[856]	[617,435,358]	0	hSpCas9	negative selection	2027783
2048597	2048620	16	+	26627737	HCT116	viability after 15 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.44326453886080547	[358]	[352,313,183]	4	hSpCas9	negative selection	2110093
2053368	2053391	16	+	26627737	HCT116	viability after 15 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.8357603057521474	[213]	[168,435,48]	7	hSpCas9	negative selection	2110094
2054386	2054409	16	+	26627737	HCT116	viability after 15 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.28585365681667674	[602]	[743,245,316]	3	hSpCas9	negative selection	2110095
2055489	2055512	16	+	26627737	HCT116	viability after 15 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.4180099536535802	[158]	[184,143,393]	9	hSpCas9	negative selection	2110096
2056222	2056245	16	-	26627737	HCT116	viability after 15 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.625187695820081	[232]	[430,266,540]	9	hSpCas9	negative selection	2110097
2056721	2056744	16	-	26627737	HCT116	viability after 15 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.2735659816212934	[856]	[486,569,176]	-3	hSpCas9	negative selection	2110098
2048597	2048620	16	+	26627737	HCT116	viability after 18 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.5039721807265383	[358]	[400,142,198]	4	hSpCas9	negative selection	2192408
2053368	2053391	16	+	26627737	HCT116	viability after 18 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	1.188441426920341	[213]	[122,387,183]	8	hSpCas9	negative selection	2192409
2054386	2054409	16	+	26627737	HCT116	viability after 18 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.3011019527959695	[602]	[469,206,412]	2	hSpCas9	negative selection	2192410
2055489	2055512	16	+	26627737	HCT116	viability after 18 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.6179755866937672	[158]	[147,44,167]	5	hSpCas9	negative selection	2192411
2056222	2056245	16	-	26627737	HCT116	viability after 18 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	1.2368087325287973	[232]	[246,173,386]	8	hSpCas9	negative selection	2192412
2056721	2056744	16	-	26627737	HCT116	viability after 18 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.053511728082915155	[856]	[734,286,269]	0	hSpCas9	negative selection	2192413
2047719	2047742	16	+	24336569	HL60	viability	CTCTCTTCTCCGGAGAGGCCCGG	TSC2	ENSG00000103197	0.7258908214287079	[37]	[132]	6	hSpCas9	negative selection	2281466
2047728	2047751	16	-	24336569	HL60	viability	GGGAGGAGCCCGGGCCTCTCCGG	TSC2	ENSG00000103197	0.39842454299991564	[260]	[727]	3	hSpCas9	negative selection	2281467
2047770	2047793	16	-	24336569	HL60	viability	GGAGCCGGAGCCTGGGACCCGGG	TSC2	ENSG00000103197	-0.948628417921804	[393]	[431]	-7	hSpCas9	negative selection	2281468
2047777	2047800	16	-	24336569	HL60	viability	CTGACCCGGAGCCGGAGCCTGGG	TSC2	ENSG00000103197	-0.8028229147303014	[520]	[631]	-6	hSpCas9	negative selection	2281469
2047791	2047814	16	-	24336569	HL60	viability	TGAGCGCGAGGATGCTGACCCGG	TSC2	ENSG00000103197	-0.1820458600797532	[1083]	[2021]	-1	hSpCas9	negative selection	2281470
2047797	2047820	16	+	24336569	HL60	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	-0.07240760484387754	[1190]	[2396]	0	hSpCas9	negative selection	2281471
2047803	2047826	16	-	24336569	HL60	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.42077589612246424	[651]	[1846]	4	hSpCas9	negative selection	2281472
2047816	2047839	16	+	24336569	HL60	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	-1.648382425880291	[436]	[294]	-9	hSpCas9	negative selection	2281473
2047825	2047848	16	-	24336569	HL60	viability	ATGTGTAGTCCGCAGGAGTCCGG	TSC2	ENSG00000103197	0.0374413046399229	[290]	[631]	0	hSpCas9	negative selection	2281474
2047832	2047855	16	-	24336569	HL60	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.43140164874590337	[464]	[1326]	4	hSpCas9	negative selection	2281475
2048614	2048637	16	-	24336569	HL60	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-0.10684941904880996	[429]	[844]	-1	hSpCas9	negative selection	2303807
2048620	2048643	16	-	24336569	HL60	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.8802116021474006	[1315]	[1512]	-7	hSpCas9	negative selection	2303808
2048625	2048648	16	-	24336569	HL60	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	0.7365577464805639	[307]	[1085]	6	hSpCas9	negative selection	2303809
2048630	2048653	16	+	24336569	HL60	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	-0.12488935163192294	[1348]	[2617]	-1	hSpCas9	negative selection	2303810
2048651	2048674	16	+	24336569	HL60	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	-0.36874605270936744	[323]	[530]	-3	hSpCas9	negative selection	2303811
2048657	2048680	16	+	24336569	HL60	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	0.10296047050853094	[384]	[874]	1	hSpCas9	negative selection	2303812
2048668	2048691	16	+	24336569	HL60	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	0.16735002903053253	[1112]	[2644]	1	hSpCas9	negative selection	2303813
2048680	2048703	16	+	24336569	HL60	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	0.08497880467434508	[506]	[1137]	0	hSpCas9	negative selection	2303814
2048690	2048713	16	+	24336569	HL60	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	0.017460131912277133	[943]	[2021]	0	hSpCas9	negative selection	2303815
2048697	2048720	16	-	24336569	HL60	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	0.07631181814729993	[211]	[472]	0	hSpCas9	negative selection	2303816
2047719	2047742	16	+	24336569	KBM7	viability	CTCTCTTCTCCGGAGAGGCCCGG	TSC2	ENSG00000103197	-0.2830074296007765	[119]	[268]	-2	hSpCas9	negative selection	2348643
2047728	2047751	16	-	24336569	KBM7	viability	GGGAGGAGCCCGGGCCTCTCCGG	TSC2	ENSG00000103197	1.0600244214660342	[165]	[943]	8	hSpCas9	negative selection	2348644
2047770	2047793	16	-	24336569	KBM7	viability	GGAGCCGGAGCCTGGGACCCGGG	TSC2	ENSG00000103197	-3.158549582182144	[549]	[167]	-9	hSpCas9	negative selection	2348645
2047777	2047800	16	-	24336569	KBM7	viability	CTGACCCGGAGCCGGAGCCTGGG	TSC2	ENSG00000103197	1.197835821082404	[221]	[1388]	8	hSpCas9	negative selection	2348646
2047791	2047814	16	-	24336569	KBM7	viability	TGAGCGCGAGGATGCTGACCCGG	TSC2	ENSG00000103197	-0.08041412892432276	[922]	[2380]	0	hSpCas9	negative selection	2348647
2047797	2047820	16	+	24336569	KBM7	viability	CAGCATCCTCGCGCTCAAGGCGG	TSC2	ENSG00000103197	-0.04704126696515365	[974]	[2573]	0	hSpCas9	negative selection	2348648
2047803	2047826	16	-	24336569	KBM7	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	-0.00741325587122077	[746]	[2026]	0	hSpCas9	negative selection	2348649
2047816	2047839	16	+	24336569	KBM7	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	-0.46252953801485425	[290]	[575]	-4	hSpCas9	negative selection	2348650
2047825	2047848	16	-	24336569	KBM7	viability	ATGTGTAGTCCGCAGGAGTCCGG	TSC2	ENSG00000103197	0.5774495979426397	[299]	[1220]	5	hSpCas9	negative selection	2348651
2047832	2047855	16	-	24336569	KBM7	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.21934339543943399	[478]	[1520]	2	hSpCas9	negative selection	2348652
2048614	2048637	16	-	24336569	KBM7	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-0.2527002677742887	[362]	[830]	-2	hSpCas9	negative selection	2370984
2048620	2048643	16	-	24336569	KBM7	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.19828829187997676	[834]	[1984]	-2	hSpCas9	negative selection	2370985
2048625	2048648	16	-	24336569	KBM7	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	-0.2259827449103574	[517]	[1207]	-2	hSpCas9	negative selection	2370986
2048630	2048653	16	+	24336569	KBM7	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	0.8580995466934048	[624]	[3089]	7	hSpCas9	negative selection	2370987
2048651	2048674	16	+	24336569	KBM7	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.7535296664196	[238]	[1098]	6	hSpCas9	negative selection	2370988
2048657	2048680	16	+	24336569	KBM7	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.006574012943501295	[350]	[952]	0	hSpCas9	negative selection	2370989
2048668	2048691	16	+	24336569	KBM7	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	-0.21520415652104163	[966]	[2271]	-2	hSpCas9	negative selection	2370990
2048680	2048703	16	+	24336569	KBM7	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	-0.27326594137874394	[692]	[1563]	-2	hSpCas9	negative selection	2370991
2048690	2048713	16	+	24336569	KBM7	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	-0.38320700586254663	[777]	[1626]	-3	hSpCas9	negative selection	2370992
2048697	2048720	16	-	24336569	KBM7	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	-0.2771321415308034	[306]	[690]	-2	hSpCas9	negative selection	2370993
2048702	2048725	16	+	24717434	HeLa	essential genes for diphteria toxin toxicity	GTCTGCAGAGGGTAAACAGACGG	TSC2	ENSG00000103197	1.5993746994665603	[784,1012,691]	[0,0,0]	5	hSpCas9	positive selection	2381519
2048721	2048743	16	+	24717434	HeLa	essential genes for diphteria toxin toxicity	ACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	2.975572120149892	[325,383,250]	[0,0,0]	6	hSpCas9	positive selection	2381520
2050417	2050439	16	+	24717434	HeLa	essential genes for diphteria toxin toxicity	TGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.5907832214346336	[1826,1705,1494]	[0,0,0]	2	hSpCas9	positive selection	2381521
2048702	2048725	16	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GTCTGCAGAGGGTAAACAGACGG	TSC2	ENSG00000103197	1.598263594226618	[784,1012,691]	[0,0,0]	4	hSpCas9	positive selection	2382962
2048721	2048743	16	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	2.9743786921581012	[325,383,250]	[0,0,0]	5	hSpCas9	positive selection	2382963
2050417	2050439	16	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.590274318970458	[1826,1705,1494]	[0,0,0]	1	hSpCas9	positive selection	2382964
2047867	2047890	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATCCTTGCATCACGTGACGG	TSC2	ENSG00000103197	0.38881623426388956	[48,35]	[18,3]	1	dCas9-VP64	positive selection	2384135
2047816	2047839	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	0.09567302426918789	[13,56]	[5,9]	0	dCas9-VP64	positive selection	2384136
2047791	2047814	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGCGCGAGGATGCTGACCCGG	TSC2	ENSG00000103197	0.053119572423008576	[10,288]	[5,64]	0	dCas9-VP64	positive selection	2384137
2080501	2080524	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGACAGAGTCTTGCTCTGTGG	TSC2	ENSG00000103197	0.4888228337382956	[6,118]	[1,37]	2	dCas9-VP64	positive selection	2387170
2047949	2047972	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCCGCGCAATGCCGCTACCGG	TSC2	ENSG00000103197	1.2409111961254942	[175,138]	[12,155]	5	dCas9-VP64	positive selection	2430598
2047970	2047993	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGTGCGGGTCGCGCTTCCGG	TSC2	ENSG00000103197	-2.0698038463692248	[222,98]	[2,13]	-9	dCas9-VP64	positive selection	2430599
2048012	2048035	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTGCGCCTTTCTCCGCGTCGG	TSC2	ENSG00000103197	-0.06885148438378169	[81,140]	[38,5]	0	dCas9-VP64	positive selection	2430600
2069340	2069363	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTCTGTCGCCCCAG	TSC2	ENSG00000103197	-0.5315818005101806	[14,129]	[5,15]	-3	dCas9-VP64	positive selection	2444205
2047867	2047890	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATCCTTGCATCACGTGACGG	TSC2	ENSG00000103197	-0.04793934750856721	[74,113]	[25,32]	0	dCas9-VP64	positive selection	2479390
2047816	2047839	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	-0.7326727979717348	[194,414]	[60,57]	-7	dCas9-VP64	positive selection	2479391
2047791	2047814	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGCGCGAGGATGCTGACCCGG	TSC2	ENSG00000103197	0.5329535168182117	[200,143]	[113,51]	4	dCas9-VP64	positive selection	2479392
2080501	2080524	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGACAGAGTCTTGCTCTGTGG	TSC2	ENSG00000103197	-0.01585891051551286	[50,117]	[22,29]	0	dCas9-VP64	positive selection	2482425
2047949	2047972	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCCGCGCAATGCCGCTACCGG	TSC2	ENSG00000103197	-0.089788151528369	[102,242]	[49,54]	0	dCas9-VP64	positive selection	2525853
2047970	2047993	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGTGCGGGTCGCGCTTCCGG	TSC2	ENSG00000103197	0.2421377977643976	[105,263]	[28,108]	2	dCas9-VP64	positive selection	2525854
2048012	2048035	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTGCGCCTTTCTCCGCGTCGG	TSC2	ENSG00000103197	-0.6007744979535276	[114,81]	[23,17]	-6	dCas9-VP64	positive selection	2525855
2069340	2069363	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTCTGTCGCCCCAG	TSC2	ENSG00000103197	0.35722745049512583	[51,32]	[17,15]	3	dCas9-VP64	positive selection	2539460
2048651	2048674	16	+	27260157	DLD1	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.0294298414276303	[]	[]	0	hSpCas9	negative selection	2579133
2048697	2048720	16	-	27260157	DLD1	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	-0.348713401115003	[]	[]	-3	hSpCas9	negative selection	2580452
2048620	2048643	16	-	27260157	DLD1	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.111540668747694	[]	[]	-1	hSpCas9	negative selection	2582050
2048657	2048680	16	+	27260157	DLD1	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.794994723691981	[]	[]	-6	hSpCas9	negative selection	2582906
2055489	2055512	16	+	27260157	DLD1	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.04279595657886	[]	[]	9	hSpCas9	negative selection	2583118
2048690	2048713	16	+	27260157	DLD1	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	0.619647901890381	[]	[]	8	hSpCas9	negative selection	2587675
2054364	2054387	16	-	27260157	DLD1	viability	AAACCTCCAGCCTTTCGTGAAGG	TSC2	ENSG00000103197	1.29148581314368	[]	[]	9	hSpCas9	negative selection	2605682
2050416	2050439	16	+	27260157	DLD1	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.637912218165102	[]	[]	8	hSpCas9	negative selection	2607130
2048625	2048648	16	-	27260157	DLD1	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	-0.040011968342839	[]	[]	0	hSpCas9	negative selection	2607402
2055448	2055471	16	+	27260157	DLD1	viability	CCTTCTGGTGCTGGTGAACTTGG	TSC2	ENSG00000103197	-0.411900490873464	[]	[]	-3	hSpCas9	negative selection	2613398
2048668	2048691	16	+	27260157	DLD1	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	1.01762603649535	[]	[]	9	hSpCas9	negative selection	2615685
2048614	2048637	16	-	27260157	DLD1	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-1.24221104920489	[]	[]	-7	hSpCas9	negative selection	2619522
2048630	2048653	16	+	27260157	DLD1	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	-0.279764421603822	[]	[]	-2	hSpCas9	negative selection	2641010
2050420	2050443	16	-	27260157	DLD1	viability	TCATCCGGATGCGATTGTTGAGG	TSC2	ENSG00000103197	-0.0157607435205875	[]	[]	0	hSpCas9	negative selection	2641120
2053425	2053448	16	+	27260157	DLD1	viability	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.0221333109082743	[]	[]	0	hSpCas9	negative selection	2642494
2053340	2053363	16	+	27260157	DLD1	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.0887500011052774	[]	[]	0	hSpCas9	negative selection	2646863
2048680	2048703	16	+	27260157	DLD1	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	0.940948251076102	[]	[]	9	hSpCas9	negative selection	2647003
2048737	2048760	16	-	27260157	DLD1	viability	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	0.134375402577185	[]	[]	3	hSpCas9	negative selection	2647780
2048651	2048674	16	+	27260157	HT1080	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.205931769347251	[]	[]	2	hSpCas9	negative selection	2655263
2048697	2048720	16	-	27260157	HT1080	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	-1.28630246935608	[]	[]	-9	hSpCas9	negative selection	2656582
2048620	2048643	16	-	27260157	HT1080	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.7407259757845	[]	[]	-8	hSpCas9	negative selection	2658180
2048657	2048680	16	+	27260157	HT1080	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.604408336856834	[]	[]	-8	hSpCas9	negative selection	2659036
2055489	2055512	16	+	27260157	HT1080	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.748886197293043	[]	[]	6	hSpCas9	negative selection	2659248
2048690	2048713	16	+	27260157	HT1080	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	-0.305551989380102	[]	[]	-7	hSpCas9	negative selection	2663805
2054364	2054387	16	-	27260157	HT1080	viability	AAACCTCCAGCCTTTCGTGAAGG	TSC2	ENSG00000103197	0.524746946919497	[]	[]	4	hSpCas9	negative selection	2681812
2050416	2050439	16	+	27260157	HT1080	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.407060116203082	[]	[]	3	hSpCas9	negative selection	2683260
2048625	2048648	16	-	27260157	HT1080	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	1.1015498092282	[]	[]	8	hSpCas9	negative selection	2683532
2055448	2055471	16	+	27260157	HT1080	viability	CCTTCTGGTGCTGGTGAACTTGG	TSC2	ENSG00000103197	-1.17207161734463	[]	[]	-8	hSpCas9	negative selection	2689528
2048668	2048691	16	+	27260157	HT1080	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	-0.518369549143626	[]	[]	-7	hSpCas9	negative selection	2691815
2048614	2048637	16	-	27260157	HT1080	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-1.34502118540911	[]	[]	-9	hSpCas9	negative selection	2695652
2048630	2048653	16	+	27260157	HT1080	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	0.501417177036447	[]	[]	4	hSpCas9	negative selection	2717140
2050420	2050443	16	-	27260157	HT1080	viability	TCATCCGGATGCGATTGTTGAGG	TSC2	ENSG00000103197	-1.78835011415878	[]	[]	-9	hSpCas9	negative selection	2717250
2053425	2053448	16	+	27260157	HT1080	viability	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.168314129548854	[]	[]	0	hSpCas9	negative selection	2718624
2053340	2053363	16	+	27260157	HT1080	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.605690494561327	[]	[]	5	hSpCas9	negative selection	2722993
2048680	2048703	16	+	27260157	HT1080	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	0.00371979076480505	[]	[]	0	hSpCas9	negative selection	2723133
2048737	2048760	16	-	27260157	HT1080	viability	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-0.9402704650804	[]	[]	-8	hSpCas9	negative selection	2723910
2048651	2048674	16	+	27260157	MKN45	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.0253507595578965	[]	[]	0	hSpCas9	negative selection	2731393
2048697	2048720	16	-	27260157	MKN45	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	-1.1633361484868	[]	[]	-8	hSpCas9	negative selection	2732712
2048620	2048643	16	-	27260157	MKN45	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.367524490517742	[]	[]	-1	hSpCas9	negative selection	2734310
2048657	2048680	16	+	27260157	MKN45	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.476694897716821	[]	[]	-6	hSpCas9	negative selection	2735166
2055489	2055512	16	+	27260157	MKN45	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.412334869557429	[]	[]	-6	hSpCas9	negative selection	2735378
2048690	2048713	16	+	27260157	MKN45	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	-1.83202942085703	[]	[]	-9	hSpCas9	negative selection	2739935
2054364	2054387	16	-	27260157	MKN45	viability	AAACCTCCAGCCTTTCGTGAAGG	TSC2	ENSG00000103197	0.694658719352976	[]	[]	7	hSpCas9	negative selection	2757942
2050416	2050439	16	+	27260157	MKN45	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.947327345600122	[]	[]	-7	hSpCas9	negative selection	2759390
2048625	2048648	16	-	27260157	MKN45	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	1.10217807201742	[]	[]	8	hSpCas9	negative selection	2759662
2055448	2055471	16	+	27260157	MKN45	viability	CCTTCTGGTGCTGGTGAACTTGG	TSC2	ENSG00000103197	-2.17265125332108	[]	[]	-9	hSpCas9	negative selection	2765658
2048668	2048691	16	+	27260157	MKN45	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	-1.16986396789904	[]	[]	-8	hSpCas9	negative selection	2767945
2048614	2048637	16	-	27260157	MKN45	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-0.959110393591969	[]	[]	-7	hSpCas9	negative selection	2771782
2048630	2048653	16	+	27260157	MKN45	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	-0.0610368706435093	[]	[]	0	hSpCas9	negative selection	2793270
2050420	2050443	16	-	27260157	MKN45	viability	TCATCCGGATGCGATTGTTGAGG	TSC2	ENSG00000103197	-2.95113256744097	[]	[]	-9	hSpCas9	negative selection	2793380
2053425	2053448	16	+	27260157	MKN45	viability	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.377841576235384	[]	[]	-1	hSpCas9	negative selection	2794754
2053340	2053363	16	+	27260157	MKN45	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-1.16358682284831	[]	[]	-8	hSpCas9	negative selection	2799123
2048680	2048703	16	+	27260157	MKN45	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	-0.244910163398508	[]	[]	-1	hSpCas9	negative selection	2799263
2048737	2048760	16	-	27260157	MKN45	viability	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-2.30184359305976	[]	[]	-9	hSpCas9	negative selection	2800040
2048651	2048674	16	+	27260157	RKO	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.22090527454384	[]	[]	1	hSpCas9	negative selection	2807523
2048697	2048720	16	-	27260157	RKO	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	0.243870862603587	[]	[]	1	hSpCas9	negative selection	2808842
2048620	2048643	16	-	27260157	RKO	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.321928700824465	[]	[]	-6	hSpCas9	negative selection	2810440
2048657	2048680	16	+	27260157	RKO	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.00477907182985984	[]	[]	0	hSpCas9	negative selection	2811296
2055489	2055512	16	+	27260157	RKO	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.551370555977511	[]	[]	3	hSpCas9	negative selection	2811508
2048690	2048713	16	+	27260157	RKO	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	-0.12232944140771	[]	[]	0	hSpCas9	negative selection	2816065
2054364	2054387	16	-	27260157	RKO	viability	AAACCTCCAGCCTTTCGTGAAGG	TSC2	ENSG00000103197	0.508553683982138	[]	[]	2	hSpCas9	negative selection	2834072
2050416	2050439	16	+	27260157	RKO	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	1.03402932115606	[]	[]	9	hSpCas9	negative selection	2835520
2048625	2048648	16	-	27260157	RKO	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	1.01880515925086	[]	[]	9	hSpCas9	negative selection	2835792
2055448	2055471	16	+	27260157	RKO	viability	CCTTCTGGTGCTGGTGAACTTGG	TSC2	ENSG00000103197	-0.435329466986956	[]	[]	-6	hSpCas9	negative selection	2841788
2048668	2048691	16	+	27260157	RKO	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	0.539301139335655	[]	[]	3	hSpCas9	negative selection	2844075
2048614	2048637	16	-	27260157	RKO	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	-0.242046404696676	[]	[]	-1	hSpCas9	negative selection	2847912
2048630	2048653	16	+	27260157	RKO	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	0.71712253163938	[]	[]	8	hSpCas9	negative selection	2869400
2050420	2050443	16	-	27260157	RKO	viability	TCATCCGGATGCGATTGTTGAGG	TSC2	ENSG00000103197	-1.31369782819408	[]	[]	-8	hSpCas9	negative selection	2869510
2053425	2053448	16	+	27260157	RKO	viability	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	0.289235218942293	[]	[]	1	hSpCas9	negative selection	2870884
2053340	2053363	16	+	27260157	RKO	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.682707897807602	[]	[]	7	hSpCas9	negative selection	2875253
2048680	2048703	16	+	27260157	RKO	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	0.978087568789457	[]	[]	9	hSpCas9	negative selection	2875393
2048737	2048760	16	-	27260157	RKO	viability	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	0.0479970635575804	[]	[]	0	hSpCas9	negative selection	2876170
2048651	2048674	16	+	27260157	SF268	viability	GGAGAAGTTTAAGATTCTGTTGG	TSC2	ENSG00000103197	0.266408288232531	[]	[]	4	hSpCas9	negative selection	2883653
2048697	2048720	16	-	27260157	SF268	viability	TGTTTACCCTCTGCAGACCTGGG	TSC2	ENSG00000103197	0.340912921565221	[]	[]	4	hSpCas9	negative selection	2884972
2048620	2048643	16	-	27260157	SF268	viability	TGAATCTTTGCTTGTTGGTTTGG	TSC2	ENSG00000103197	-0.997940138577795	[]	[]	-7	hSpCas9	negative selection	2886570
2048657	2048680	16	+	27260157	SF268	viability	GTTTAAGATTCTGTTGGGACTGG	TSC2	ENSG00000103197	-0.705903848581484	[]	[]	-5	hSpCas9	negative selection	2887426
2055489	2055512	16	+	27260157	SF268	viability	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.981643561784904	[]	[]	9	hSpCas9	negative selection	2887638
2048690	2048713	16	+	27260157	SF268	viability	GCCAAATCCCAGGTCTGCAGAGG	TSC2	ENSG00000103197	-0.834485703907153	[]	[]	-6	hSpCas9	negative selection	2892195
2054364	2054387	16	-	27260157	SF268	viability	AAACCTCCAGCCTTTCGTGAAGG	TSC2	ENSG00000103197	1.3071893893458	[]	[]	9	hSpCas9	negative selection	2910202
2050416	2050439	16	+	27260157	SF268	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.665910708248354	[]	[]	8	hSpCas9	negative selection	2911650
2048625	2048648	16	-	27260157	SF268	viability	AAGCCTGAATCTTTGCTTGTTGG	TSC2	ENSG00000103197	0.986847272043779	[]	[]	9	hSpCas9	negative selection	2911922
2055448	2055471	16	+	27260157	SF268	viability	CCTTCTGGTGCTGGTGAACTTGG	TSC2	ENSG00000103197	0.744233928609656	[]	[]	8	hSpCas9	negative selection	2917918
2048668	2048691	16	+	27260157	SF268	viability	TGTTGGGACTGGGAACACCGAGG	TSC2	ENSG00000103197	0.0753302517062	[]	[]	0	hSpCas9	negative selection	2920205
2048614	2048637	16	-	27260157	SF268	viability	TTTGCTTGTTGGTTTGGCCATGG	TSC2	ENSG00000103197	0.260225441832098	[]	[]	4	hSpCas9	negative selection	2924042
2048630	2048653	16	+	27260157	SF268	viability	AAGCAAAGATTCAGGCTTGAAGG	TSC2	ENSG00000103197	0.499503025481776	[]	[]	7	hSpCas9	negative selection	2945530
2050420	2050443	16	-	27260157	SF268	viability	TCATCCGGATGCGATTGTTGAGG	TSC2	ENSG00000103197	0.478942605740097	[]	[]	7	hSpCas9	negative selection	2945640
2053425	2053448	16	+	27260157	SF268	viability	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	0.474049878493913	[]	[]	7	hSpCas9	negative selection	2947014
2053340	2053363	16	+	27260157	SF268	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.532511181397934	[]	[]	8	hSpCas9	negative selection	2951383
2048680	2048703	16	+	27260157	SF268	viability	GAACACCGAGGCCAAATCCCAGG	TSC2	ENSG00000103197	1.26130380863853	[]	[]	9	hSpCas9	negative selection	2951523
2048737	2048760	16	-	27260157	SF268	viability	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	0.827865363337515	[]	[]	8	hSpCas9	negative selection	2952300
2048737	2048760	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-0.030181064942530034	[5,5]	[3,4]	0	hSpCas9	positive selection	3029552
2075819	2075842	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	0.2654294997785264	[3,2]	[3,2]	5	hSpCas9	positive selection	3029553
2048721	2048744	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	-0.3664108389414276	[4,4]	[4,1]	-5	hSpCas9	positive selection	3029554
2064302	2064325	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.2830014584852072	[3,3]	[0,0]	-9	hSpCas9	positive selection	3029555
2048737	2048760	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	0.18229539279538853	[5,5]	[4,3]	3	hSpCas9	positive selection	3097410
2075819	2075842	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	-0.24198152861122652	[3,3]	[3,0]	-4	hSpCas9	positive selection	3097411
2048721	2048744	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	0.5117874813685586	[4,4]	[3,5]	8	hSpCas9	positive selection	3097412
2064302	2064325	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	0.06254860016300842	[3,3]	[2,1]	1	hSpCas9	positive selection	3097413
2053340	2053363		+	24336571	A375	resistance to PLX after 7 days	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.4602775972360802	[25,21]	[33,31]	9	hSpCas9	positive selection	3152994
2050416	2050439		+	24336571	A375	resistance to PLX after 7 days	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.07314000454454961	[30,38]	[35,36]	2	hSpCas9	positive selection	3152995
2053425	2053448		+	24336571	A375	resistance to PLX after 7 days	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	0.37395701913330903	[30,30]	[37,41]	8	hSpCas9	positive selection	3152996
2053340	2053363		+	24336571	A375	resistance to PLX after 14 days	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.21674269210481967	[14,31]	[13,10]	2	hSpCas9	positive selection	3210787
2050416	2050439		+	24336571	A375	resistance to PLX after 14 days	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	1.6147958964349898	[26,29]	[16,63]	9	hSpCas9	positive selection	3210788
2053425	2053448		+	24336571	A375	resistance to PLX after 14 days	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	0.5308473813860369	[29,17]	[14,16]	5	hSpCas9	positive selection	3210789
2053340	2053363		+	24336571	A375	viability after 7 days	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.6441878785102595	[38]	[25,21]	-7	hSpCas9	negative selection	3268580
2050416	2050439		+	24336571	A375	viability after 7 days	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.13238260348854158	[40]	[30,38]	-2	hSpCas9	negative selection	3268581
2053425	2053448		+	24336571	A375	viability after 7 days	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.6454124321829455	[50]	[30,30]	-7	hSpCas9	negative selection	3268582
2053340	2053363		+	24336571	A375	viability after 14 days	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.6490841573490964	[38]	[14,31]	-7	hSpCas9	negative selection	3326373
2050416	2050439		+	24336571	A375	viability after 14 days	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.42621435703074484	[40]	[26,29]	-5	hSpCas9	negative selection	3326374
2053425	2053448		+	24336571	A375	viability after 14 days	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.9839788144890823	[50]	[29,17]	-8	hSpCas9	negative selection	3326375
2050416	2050439	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-2.1520647246918667	[679,679]	[0,0]	-9	hSpCas9	positive selection	3399288
2054354	2054377	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.8719568054991315	[279,279]	[0,0]	-6	hSpCas9	positive selection	3399289
2053340	2053363	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-1.3720304086337745	[395,395]	[0,0]	-8	hSpCas9	positive selection	3399290
2048737	2048760	16	-	26780180	HT29	viability (Avana library 4 designs)	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-0.155815446936471	[]	[]	-2	hSpCas9	negative selection	3468411
2075818	2075841	16	+	26780180	HT29	viability (Avana library 4 designs)	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	1.01657302894737	[]	[]	4	hSpCas9	negative selection	3468412
2048720	2048743	16	+	26780180	HT29	viability (Avana library 4 designs)	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	0.165076232249944	[]	[]	0	hSpCas9	negative selection	3468413
2064301	2064324	16	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	1.19086158470882	[]	[]	4	hSpCas9	negative selection	3468414
2048737	2048760	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-13.6770247777215	[]	[]	-8	hSpCas9	negative selection	3573070
2048720	2048743	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	-0.134545704729662	[]	[]	0	hSpCas9	negative selection	3573071
2064301	2064324	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.52919339653113	[]	[]	-2	hSpCas9	negative selection	3573072
2075818	2075841	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	-8.33273488663522	[]	[]	-7	hSpCas9	negative selection	3573073
2056704	2056727	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGAGGGTAACGATGAACAGCGG	TSC2	ENSG00000103197	-13.6167753101928	[]	[]	-8	hSpCas9	negative selection	3573074
2056670	2056693	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTGCTACAACTGCCTGCCGG	TSC2	ENSG00000103197	-15.1496958197098	[]	[]	-9	hSpCas9	negative selection	3573075
2048737	2048760	16	-	26780180	A375	viability (Avana lentiGuide)	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	14.7036519769845	[]	[]	8	hSpCas9	negative selection	3681729
2048720	2048743	16	+	26780180	A375	viability (Avana lentiGuide)	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	8.58000536256147	[]	[]	6	hSpCas9	negative selection	3681730
2064301	2064324	16	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	6.07305272142052	[]	[]	5	hSpCas9	negative selection	3681731
2075818	2075841	16	+	26780180	A375	viability (Avana lentiGuide)	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	24.7281583401565	[]	[]	9	hSpCas9	negative selection	3681732
2056704	2056727	16	-	26780180	A375	viability (Avana lentiGuide)	CAGAGGGTAACGATGAACAGCGG	TSC2	ENSG00000103197	22.7994020832224	[]	[]	9	hSpCas9	negative selection	3681733
2056670	2056693	16	+	26780180	A375	viability (Avana lentiGuide)	GGTCTGCTACAACTGCCTGCCGG	TSC2	ENSG00000103197	22.4770640756236	[]	[]	9	hSpCas9	negative selection	3681734
2048737	2048760	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-0.3510664977227713	[6]	[5,4]	-5	hSpCas9	positive selection	3790336
2048720	2048743	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	-0.0065683521614036955	[6]	[6,5]	0	hSpCas9	positive selection	3790337
2064301	2064324	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.26139940272305395	[4]	[4,1]	-4	hSpCas9	positive selection	3790338
2075818	2075841	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	-0.2519826124276101	[4]	[4,2]	-4	hSpCas9	positive selection	3790339
2056704	2056727	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGAGGGTAACGATGAACAGCGG	TSC2	ENSG00000103197	-0.40431287967028656	[4]	[3,2]	-5	hSpCas9	positive selection	3790340
2056670	2056693	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTGCTACAACTGCCTGCCGG	TSC2	ENSG00000103197	-1.0908048555303533	[4]	[1,1]	-9	hSpCas9	positive selection	3790341
2048737	2048760	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCACTCTCAGTATTTCCGCGG	TSC2	ENSG00000103197	-0.054025415178889646	[7]	[5,5]	-1	hSpCas9	positive selection	3898943
2048720	2048743	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGGAGTTTATCATCACCGCGG	TSC2	ENSG00000103197	-0.5146682608480527	[6]	[4,2]	-6	hSpCas9	positive selection	3898944
2064301	2064324	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.2659322343886406	[4]	[0,1]	-9	hSpCas9	positive selection	3898945
2075818	2075841	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTACAGGAACTTTGCCGCGG	TSC2	ENSG00000103197	-0.5467558088846897	[4]	[2,2]	-6	hSpCas9	positive selection	3898946
2056704	2056727	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGAGGGTAACGATGAACAGCGG	TSC2	ENSG00000103197	-1.1278363790829242	[5]	[1,1]	-8	hSpCas9	positive selection	3898947
2056670	2056693	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTGCTACAACTGCCTGCCGG	TSC2	ENSG00000103197	-0.5498354583010405	[5]	[2,3]	-6	hSpCas9	positive selection	3898948
2053340	2053363	16	+	26780180	A375	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	1.79662981236637	[]	[]	9	hSpCas9	negative selection	4008244
2050435	2050458	16	-	26780180	A375	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	2.39239930087829	[]	[]	9	hSpCas9	negative selection	4008245
2054354	2054377	16	+	26780180	A375	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.73580533858599	[]	[]	9	hSpCas9	negative selection	4008246
2053368	2053391	16	+	26780180	A375	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.320429291889332	[]	[]	0	hSpCas9	negative selection	4008247
2050416	2050439	16	+	26780180	A375	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	2.09500463954185	[]	[]	9	hSpCas9	negative selection	4008248
2054286	2054309	16	+	26780180	A375	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.445287372438955	[]	[]	1	hSpCas9	negative selection	4008249
2053340	2053363	16	+	26780180	HT29	viability (GeCKOv2 library)	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	1.4218869388094	[]	[]	7	hSpCas9	negative selection	4116210
2050435	2050458	16	-	26780180	HT29	viability (GeCKOv2 library)	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	1.7689029874744	[]	[]	8	hSpCas9	negative selection	4116211
2054354	2054377	16	+	26780180	HT29	viability (GeCKOv2 library)	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.602208206571603	[]	[]	2	hSpCas9	negative selection	4116212
2053368	2053391	16	+	26780180	HT29	viability (GeCKOv2 library)	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.939643824097081	[]	[]	4	hSpCas9	negative selection	4116213
2050416	2050439	16	+	26780180	HT29	viability (GeCKOv2 library)	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	1.16417770062221	[]	[]	5	hSpCas9	negative selection	4116214
2054286	2054309	16	+	26780180	HT29	viability (GeCKOv2 library)	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.290330403496408	[]	[]	0	hSpCas9	negative selection	4116215
2047832	2047855	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.43155960280043926	[3]	[1,0]	-8	hSpCas9	positive selection	4156531
2047803	2047826	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.20734995357251762	[4]	[3,2]	5	hSpCas9	positive selection	4156533
2053340	2053363	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.28818923792165096	[4]	[3,3]	7	hSpCas9	positive selection	4179594
2050416	2050439	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.34637497134408357	[5]	[4,4]	8	hSpCas9	positive selection	4179595
2053425	2053448	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	0.4029612722589878	[4]	[5,3]	8	hSpCas9	positive selection	4179596
2047832	2047855	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.6207620865098673	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4220553
2047803	2047826	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.2385035495201189	[3]	[5,3,0,0]	2	hSpCas9	positive selection	4220555
2053340	2053363	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.6248700325463625	[5]	[0,4,0,0]	-8	hSpCas9	positive selection	4243616
2050416	2050439	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.11805732432340761	[4]	[0,2,4,0]	-2	hSpCas9	positive selection	4243617
2053425	2053448	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGCTGAAGGCCATCGTGCAGG	TSC2	ENSG00000103197	-0.32112635164633674	[5]	[0,1,5,0]	-5	hSpCas9	positive selection	4243618
2047803	2047826	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6769317296076496	[1]	[2,2]	9	hSpCas9	positive selection	4286498
2053368	2053391	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.2500197358990096	[2]	[2,2]	5	hSpCas9	positive selection	4305433
2054286	2054309	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.3819530978721087	[3]	[4,3]	7	hSpCas9	positive selection	4305434
2050435	2050458	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.17925253441154138	[4]	[3,2]	-4	hSpCas9	positive selection	4305435
2047832	2047855	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-1.0498303807318718	[2]	[0,0]	-9	hSpCas9	positive selection	4350756
2050416	2050439	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.3355152651336041	[3]	[3,1]	-6	hSpCas9	positive selection	4369682
2054354	2054377	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.14590000092257888	[2]	[2,1]	-3	hSpCas9	positive selection	4369683
2053340	2053363	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.4095378386336678	[3]	[2,3]	8	hSpCas9	positive selection	4369684
2062980	2063002	16	-	27760321	OCIAML3	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-1.1034318310241713	[524,613]	[207,210]	-7	hSpCas9	negative selection	4450512
2070487	2070509	16	-	27760321	OCIAML3	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.7450857106902857	[974,832]	[426,411]	-6	hSpCas9	negative selection	4450513
2055490	2055512	16	+	27760321	OCIAML3	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.3262742425669003	[553,495]	[376,261]	-3	hSpCas9	negative selection	4450514
2056721	2056743	16	-	27760321	OCIAML3	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-1.2513302260281804	[594,485]	[111,260]	-8	hSpCas9	negative selection	4450515
2060671	2060693	16	-	27760321	OCIAML3	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4450516
2062980	2063002	16	-	27760321	OCIAML2	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-0.5842424493720179	[524,613]	[270,361]	-6	hSpCas9	negative selection	4533975
2070487	2070509	16	-	27760321	OCIAML2	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-1.2868937188150078	[974,832]	[249,362]	-8	hSpCas9	negative selection	4533976
2055490	2055512	16	+	27760321	OCIAML2	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.3176976584736328	[553,495]	[332,349]	-4	hSpCas9	negative selection	4533977
2056721	2056743	16	-	27760321	OCIAML2	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-1.7665252627457464	[594,485]	[104,157]	-9	hSpCas9	negative selection	4533978
2060671	2060693	16	-	27760321	OCIAML2	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4533979
2062980	2063002	16	-	27760321	MV411	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-1.352632847297877	[524,613]	[132,171]	-7	hSpCas9	negative selection	4617438
2070487	2070509	16	-	27760321	MV411	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-1.7516397583462133	[974,832]	[168,187]	-8	hSpCas9	negative selection	4617439
2055490	2055512	16	+	27760321	MV411	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.5831482195553861	[553,495]	[190,290]	-4	hSpCas9	negative selection	4617440
2056721	2056743	16	-	27760321	MV411	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.29551403394112696	[594,485]	[2,718]	-2	hSpCas9	negative selection	4617441
2060671	2060693	16	-	27760321	MV411	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4617442
2062980	2063002	16	-	27760321	HL60	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.7010261201381776	[524,613]	[700,829]	7	hSpCas9	negative selection	4700901
2070487	2070509	16	-	27760321	HL60	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	0.2405719710555012	[974,832]	[925,809]	3	hSpCas9	negative selection	4700902
2055490	2055512	16	+	27760321	HL60	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.07683054997427985	[553,495]	[426,477]	0	hSpCas9	negative selection	4700903
2056721	2056743	16	-	27760321	HL60	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.35513919881878764	[594,485]	[457,221]	-4	hSpCas9	negative selection	4700904
2060671	2060693	16	-	27760321	HL60	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4700905
2062980	2063002	16	-	27760321	HT1080	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-5.015996973627183	[613,478]	[0,12]	-8	hSpCas9	negative selection	4784364
2070487	2070509	16	-	27760321	HT1080	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-8.20646850283902	[832,649]	[0,0]	-9	hSpCas9	negative selection	4784365
2055490	2055512	16	+	27760321	HT1080	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-1.3018287738625494	[495,386]	[88,51]	-5	hSpCas9	negative selection	4784366
2056721	2056743	16	-	27760321	HT1080	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-1.3770557740859557	[485,378]	[125,0]	-5	hSpCas9	negative selection	4784367
2060671	2060693	16	-	27760321	HT1080	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	8.239698650569562	[0,0]	[64,184]	9	hSpCas9	negative selection	4784368
2062980	2063002	16	-	27760321	HT29	viability after 7 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-0.38223525627600397	[613,478]	[637,593,402]	-5	hSpCas9	negative selection	4867827
2070487	2070509	16	-	27760321	HT29	viability after 7 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.2685832137809293	[832,649]	[768,908,694]	-4	hSpCas9	negative selection	4867828
2055490	2055512	16	+	27760321	HT29	viability after 7 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.5715902097232037	[495,386]	[1038,756,763]	8	hSpCas9	negative selection	4867829
2056721	2056743	16	-	27760321	HT29	viability after 7 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.14700868331409006	[485,378]	[515,655,340]	-2	hSpCas9	negative selection	4867830
2060671	2060693	16	-	27760321	HT29	viability after 7 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4867831
2062980	2063002	16	-	27760321	HT29	viability after 25 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.3124812263628899	[613,478]	[733,776,821]	3	hSpCas9	negative selection	4951290
2070487	2070509	16	-	27760321	HT29	viability after 25 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	0.14043918961083168	[832,649]	[888,803,1130]	1	hSpCas9	negative selection	4951291
2055490	2055512	16	+	27760321	HT29	viability after 25 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.9371955681735937	[495,386]	[901,1143,841]	9	hSpCas9	negative selection	4951292
2056721	2056743	16	-	27760321	HT29	viability after 25 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.5247656167180477	[485,378]	[951,556,595]	6	hSpCas9	negative selection	4951293
2060671	2060693	16	-	27760321	HT29	viability after 25 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4951294
2062980	2063002	16	-	27760321	HT29	viability after 22 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.11487728462793945	[613,478]	[579,703,771]	1	hSpCas9	negative selection	5034753
2070487	2070509	16	-	27760321	HT29	viability after 22 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.069268511332786	[832,649]	[1041,787,612]	0	hSpCas9	negative selection	5034754
2055490	2055512	16	+	27760321	HT29	viability after 22 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.5976873441126254	[495,386]	[726,952,636]	6	hSpCas9	negative selection	5034755
2056721	2056743	16	-	27760321	HT29	viability after 22 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.30176095107927603	[485,378]	[673,479,693]	3	hSpCas9	negative selection	5034756
2060671	2060693	16	-	27760321	HT29	viability after 22 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5034757
2062980	2063002	16	-	27760321	HT29	viability after 19 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.24136960847150668	[613,478]	[691,965,559]	2	hSpCas9	negative selection	5118216
2070487	2070509	16	-	27760321	HT29	viability after 19 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.0063548633106393915	[832,649]	[748,892,878]	0	hSpCas9	negative selection	5118217
2055490	2055512	16	+	27760321	HT29	viability after 19 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.6951593899247583	[495,386]	[1408,397,710]	7	hSpCas9	negative selection	5118218
2056721	2056743	16	-	27760321	HT29	viability after 19 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.37085626005398586	[485,378]	[855,471,613]	3	hSpCas9	negative selection	5118219
2060671	2060693	16	-	27760321	HT29	viability after 19 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5118220
2062980	2063002	16	-	27760321	HT29	viability after 16 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-0.12934225474874006	[613,478]	[457,570,637]	-1	hSpCas9	negative selection	5201679
2070487	2070509	16	-	27760321	HT29	viability after 16 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.010818172313047603	[832,649]	[843,898,726]	0	hSpCas9	negative selection	5201680
2055490	2055512	16	+	27760321	HT29	viability after 16 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.6988650453874117	[495,386]	[1203,541,703]	7	hSpCas9	negative selection	5201681
2056721	2056743	16	-	27760321	HT29	viability after 16 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.09776488388441157	[485,378]	[621,368,575]	1	hSpCas9	negative selection	5201682
2060671	2060693	16	-	27760321	HT29	viability after 16 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5201683
2062980	2063002	16	-	27760321	HT29	viability after 13 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.04340156178067467	[613,478]	[616,774,572]	0	hSpCas9	negative selection	5285142
2070487	2070509	16	-	27760321	HT29	viability after 13 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	0.06917284155722725	[832,649]	[635,1035,1027]	0	hSpCas9	negative selection	5285143
2055490	2055512	16	+	27760321	HT29	viability after 13 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.9118590731526988	[495,386]	[1165,806,919]	9	hSpCas9	negative selection	5285144
2056721	2056743	16	-	27760321	HT29	viability after 13 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.2544287800202215	[485,378]	[624,532,634]	3	hSpCas9	negative selection	5285145
2060671	2060693	16	-	27760321	HT29	viability after 13 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5285146
2062980	2063002	16	-	27760321	HT29	viability after 10 days	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	-0.5106684511689017	[613,478]	[399,600,439]	-6	hSpCas9	negative selection	5368605
2070487	2070509	16	-	27760321	HT29	viability after 10 days	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-0.04499251382250691	[832,649]	[791,1165,744]	0	hSpCas9	negative selection	5368606
2055490	2055512	16	+	27760321	HT29	viability after 10 days	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.8989489849673873	[495,386]	[1308,972,804]	9	hSpCas9	negative selection	5368607
2056721	2056743	16	-	27760321	HT29	viability after 10 days	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	0.20588599623505216	[485,378]	[631,331,889]	2	hSpCas9	negative selection	5368608
2060671	2060693	16	-	27760321	HT29	viability after 10 days	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5368609
2062980	2063002	16	-	27760321	MOLM13	viability	TTGATGCGCACGGCGCCTCGGG	TSC2	ENSG00000103197	0.265611846994804	[524,613]	[167,578]	1	hSpCas9	negative selection	5452068
2070487	2070509	16	-	27760321	MOLM13	viability	AGCATCTCATACACACGCGTGG	TSC2	ENSG00000103197	-1.296511999552044	[974,832]	[65,326]	-6	hSpCas9	negative selection	5452069
2055490	2055512	16	+	27760321	MOLM13	viability	CCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.18487336884700906	[553,495]	[424,119]	-1	hSpCas9	negative selection	5452070
2056721	2056743	16	-	27760321	MOLM13	viability	GACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-4.7516680474064765	[594,485]	[0,19]	-9	hSpCas9	negative selection	5452071
2060671	2060693	16	-	27760321	MOLM13	viability	ACCTCGTTCGGACATGCCATGG	TSC2	ENSG00000103197	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5452072
2047558	2047581	16	+	27661255	K562	viability	GGGAACGCAGGGCCGCACGTGGG	TSC2	ENSG00000103197	0.08723750861294577	[1304,1332]	[1255,1001]	3	dCas9-KRAB	negative selection	5497705
2047741	2047764	16	+	27661255	K562	viability	GGCTCCTCCCTACACCCCCGCGG	TSC2	ENSG00000103197	0.1058328442891544	[1188,1596]	[1351,1053]	3	dCas9-KRAB	negative selection	5497706
2047816	2047839	16	+	27661255	K562	viability	GCGGTCATGCCGGACTCCTGCGG	TSC2	ENSG00000103197	-0.06290207336313736	[1296,1414]	[1030,1038]	-2	dCas9-KRAB	negative selection	5497707
2047748	2047771	16	-	27661255	K562	viability	GGCTGGGCCGCGGGGGTGTAGGG	TSC2	ENSG00000103197	0.11027523002144435	[445,467]	[417,372]	4	dCas9-KRAB	negative selection	5497708
2047962	2047985	16	-	27661255	K562	viability	GCGACCCGCACTTCCGGTAGCGG	TSC2	ENSG00000103197	-0.3544265494782117	[351,346]	[259,182]	-7	dCas9-KRAB	negative selection	5520109
2048019	2048042	16	-	27661255	K562	viability	GGCCGCCCCGACGCGGAGAAAGG	TSC2	ENSG00000103197	0.33604248569033623	[704,686]	[774,639]	9	dCas9-KRAB	negative selection	5520110
2047803	2047826	16	-	27260156	BXPC3	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.2085556113643361	[151]	[161,190,177,206]	4	hSpCas9	negative selection	5558958
2053368	2053391	16	+	27260156	BXPC3	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.1906941234700164	[416]	[436,455,450,672]	4	hSpCas9	negative selection	5577893
2054286	2054309	16	+	27260156	BXPC3	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.27575847463284253	[684]	[685,757,1019,1049]	6	hSpCas9	negative selection	5577894
2050435	2050458	16	-	27260156	BXPC3	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.22348285792327394	[1540]	[1611,1769,2026,2177]	5	hSpCas9	negative selection	5577895
2047832	2047855	16	-	27260156	BXPC3	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.4038629710686443	[240]	[196,188,155,220]	-7	hSpCas9	negative selection	5623216
2050416	2050439	16	+	27260156	BXPC3	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.2236164313032727	[948]	[1166,1206,1071,1176]	5	hSpCas9	negative selection	5642142
2054354	2054377	16	+	27260156	BXPC3	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.25232860144082925	[338]	[438,385,433,427]	5	hSpCas9	negative selection	5642143
2053340	2053363	16	+	27260156	BXPC3	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.10027433175078959	[566]	[586,617,655,689]	2	hSpCas9	negative selection	5642144
2047803	2047826	16	-	27260156	A673	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.47475590696465964	[151]	[265,217,236,297]	9	hSpCas9	negative selection	5680209
2053368	2053391	16	+	27260156	A673	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.198495582865157	[416]	[565,591,573,562]	5	hSpCas9	negative selection	5699144
2054286	2054309	16	+	27260156	A673	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.16882358528337016	[684]	[902,978,827,986]	4	hSpCas9	negative selection	5699145
2050435	2050458	16	-	27260156	A673	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.5675368104729304	[1540]	[2750,2520,2793,2912]	9	hSpCas9	negative selection	5699146
2047832	2047855	16	-	27260156	A673	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.2642164879900947	[240]	[306,403,229,448]	6	hSpCas9	negative selection	5744467
2050416	2050439	16	+	27260156	A673	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.5514798666292955	[948]	[2021,1483,1756,1445]	9	hSpCas9	negative selection	5763393
2054354	2054377	16	+	27260156	A673	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.7188621600057665	[338]	[859,649,423,774]	9	hSpCas9	negative selection	5763394
2053340	2053363	16	+	27260156	A673	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.5958065577643147	[566]	[1150,1122,825,1026]	9	hSpCas9	negative selection	5763395
2047803	2047826	16	-	27260156	A375	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.5778800982445134	[151]	[327,233,337,166]	8	hSpCas9	negative selection	5801460
2053368	2053391	16	+	27260156	A375	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.3681546708729656	[416]	[749,777,554,469]	5	hSpCas9	negative selection	5820395
2054286	2054309	16	+	27260156	A375	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.3089533498363197	[684]	[1097,1129,1040,741]	4	hSpCas9	negative selection	5820396
2050435	2050458	16	-	27260156	A375	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.16901849489106247	[1540]	[1989,2431,2094,1668]	2	hSpCas9	negative selection	5820397
2047832	2047855	16	-	27260156	A375	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.014880460585108057	[240]	[283,275,370,212]	0	hSpCas9	negative selection	5865718
2050416	2050439	16	+	27260156	A375	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.10597085366504277	[948]	[1150,1365,1258,1033]	1	hSpCas9	negative selection	5884644
2054354	2054377	16	+	27260156	A375	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.2866685707375338	[338]	[269,501,248,302]	-4	hSpCas9	negative selection	5884645
2053340	2053363	16	+	27260156	A375	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.25019249061094834	[566]	[506,279,784,607]	-4	hSpCas9	negative selection	5884646
2047803	2047826	16	-	27260156	COLO741	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.34402191102710544	[151]	[257,319,167]	7	hSpCas9	negative selection	5922711
2053368	2053391	16	+	27260156	COLO741	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.004413947776113564	[416]	[476,566,551]	0	hSpCas9	negative selection	5941646
2054286	2054309	16	+	27260156	COLO741	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.1248591187610194	[684]	[1230,784,873]	2	hSpCas9	negative selection	5941647
2050435	2050458	16	-	27260156	COLO741	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.24086408639236723	[1540]	[2150,2421,2382]	5	hSpCas9	negative selection	5941648
2047832	2047855	16	-	27260156	COLO741	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.08090857429777643	[240]	[305,360,308]	1	hSpCas9	negative selection	5986969
2050416	2050439	16	+	27260156	COLO741	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.17614832955114568	[948]	[1408,1481,1229]	4	hSpCas9	negative selection	6005895
2054354	2054377	16	+	27260156	COLO741	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.004002800204394641	[338]	[548,445,324]	0	hSpCas9	negative selection	6005896
2053340	2053363	16	+	27260156	COLO741	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.16918646639466878	[566]	[710,651,578]	-4	hSpCas9	negative selection	6005897
2047803	2047826	16	-	27260156	CAL120	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.06810564270888442	[151]	[153,172,259]	1	hSpCas9	negative selection	6043962
2053368	2053391	16	+	27260156	CAL120	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.41458325289436354	[416]	[989,572,558]	6	hSpCas9	negative selection	6062897
2054286	2054309	16	+	27260156	CAL120	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.07973234992718259	[684]	[1166,998,581]	1	hSpCas9	negative selection	6062898
2050435	2050458	16	-	27260156	CAL120	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.4339094517006188	[1540]	[3261,2501,2115]	6	hSpCas9	negative selection	6062899
2047832	2047855	16	-	27260156	CAL120	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.4253469395843823	[240]	[705,331,218]	6	hSpCas9	negative selection	6108220
2050416	2050439	16	+	27260156	CAL120	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.17123392340404098	[948]	[1358,1131,1498]	2	hSpCas9	negative selection	6127146
2054354	2054377	16	+	27260156	CAL120	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.3417878413119362	[338]	[1625,593,1070]	9	hSpCas9	negative selection	6127147
2053340	2053363	16	+	27260156	CAL120	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.23611373602292118	[566]	[1103,832,600]	3	hSpCas9	negative selection	6127148
2047803	2047826	16	-	27260156	CADOES1	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6925110387802949	[151]	[140,248,272,251]	9	hSpCas9	negative selection	6165213
2053368	2053391	16	+	27260156	CADOES1	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.3901473173990341	[416]	[464,580,614,366]	6	hSpCas9	negative selection	6184148
2054286	2054309	16	+	27260156	CADOES1	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.6204420873399733	[684]	[885,1329,741,959]	8	hSpCas9	negative selection	6184149
2050435	2050458	16	-	27260156	CADOES1	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.9708491703872444	[1540]	[2371,3331,3046,2474]	9	hSpCas9	negative selection	6184150
2047832	2047855	16	-	27260156	CADOES1	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.2104100887462068	[240]	[265,139,164,203]	-4	hSpCas9	negative selection	6229471
2050416	2050439	16	+	27260156	CADOES1	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.8682762634556951	[948]	[1417,1826,1660,1536]	9	hSpCas9	negative selection	6248397
2054354	2054377	16	+	27260156	CADOES1	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.3615572514582306	[338]	[347,264,325,691]	6	hSpCas9	negative selection	6248398
2053340	2053363	16	+	27260156	CADOES1	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.9853681747607063	[566]	[1259,934,1048,926]	9	hSpCas9	negative selection	6248399
2047803	2047826	16	-	27260156	EWS502	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.4369220335979218	[151]	[209,236,204,218]	7	hSpCas9	negative selection	6286464
2053368	2053391	16	+	27260156	EWS502	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.01831599738223419	[416]	[491,343,328,632]	0	hSpCas9	negative selection	6305399
2054286	2054309	16	+	27260156	EWS502	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.3854610851186978	[684]	[1070,811,832,1068]	6	hSpCas9	negative selection	6305400
2050435	2050458	16	-	27260156	EWS502	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.5034067980837269	[1540]	[1562,2502,2480,2820]	8	hSpCas9	negative selection	6305401
2047832	2047855	16	-	27260156	EWS502	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.16856724450882765	[240]	[258,436,254,184]	3	hSpCas9	negative selection	6350722
2050416	2050439	16	+	27260156	EWS502	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.6456298335589878	[948]	[1507,1477,1688,1625]	9	hSpCas9	negative selection	6369648
2054354	2054377	16	+	27260156	EWS502	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.8243376139371046	[338]	[570,558,447,996]	9	hSpCas9	negative selection	6369649
2053340	2053363	16	+	27260156	EWS502	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.3380051343842344	[566]	[797,550,780,918]	6	hSpCas9	negative selection	6369650
2047803	2047826	16	-	27260156	EW8	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.39625491503081123	[151]	[154,111,178,197]	7	hSpCas9	negative selection	6407715
2053368	2053391	16	+	27260156	EW8	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.12255664414600165	[416]	[467,410,308,303]	2	hSpCas9	negative selection	6426650
2054286	2054309	16	+	27260156	EW8	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.5556721868588371	[684]	[783,1005,703,783]	8	hSpCas9	negative selection	6426651
2050435	2050458	16	-	27260156	EW8	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.37376195846449156	[1540]	[1687,1873,1226,1753]	6	hSpCas9	negative selection	6426652
2047832	2047855	16	-	27260156	EW8	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.0035079771050052777	[240]	[203,286,112,193]	0	hSpCas9	negative selection	6471973
2050416	2050439	16	+	27260156	EW8	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.08567672514534719	[948]	[769,757,719,654]	-2	hSpCas9	negative selection	6490899
2054354	2054377	16	+	27260156	EW8	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.14241975416566877	[338]	[350,217,249,186]	-3	hSpCas9	negative selection	6490900
2053340	2053363	16	+	27260156	EW8	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.035101449027686804	[566]	[536,585,313,388]	0	hSpCas9	negative selection	6490901
2047803	2047826	16	-	27260156	CORL105	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.47470870359790895	[151]	[199,259,365,179]	8	hSpCas9	negative selection	6528966
2053368	2053391	16	+	27260156	CORL105	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.032553321593938145	[416]	[611,483,488,414]	0	hSpCas9	negative selection	6547901
2054286	2054309	16	+	27260156	CORL105	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.42998585194553307	[684]	[1207,1003,1116,1003]	7	hSpCas9	negative selection	6547902
2050435	2050458	16	-	27260156	CORL105	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.258875849438025	[1540]	[1405,1615,1659,1366]	-5	hSpCas9	negative selection	6547903
2047832	2047855	16	-	27260156	CORL105	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.07907321134837997	[240]	[265,254,363,316]	1	hSpCas9	negative selection	6593224
2050416	2050439	16	+	27260156	CORL105	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.32861479256201465	[948]	[917,668,990,981]	-6	hSpCas9	negative selection	6612150
2054354	2054377	16	+	27260156	CORL105	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.8522721264848687	[338]	[194,251,214,214]	-9	hSpCas9	negative selection	6612151
2053340	2053363	16	+	27260156	CORL105	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.5872311622281916	[566]	[478,422,473,397]	-8	hSpCas9	negative selection	6612152
2047803	2047826	16	-	27260156	HS294T	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.34209492729034996	[151]	[80,79,55,80]	4	hSpCas9	negative selection	6650217
2053368	2053391	16	+	27260156	HS294T	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.11344674398154005	[416]	[161,229,161,135]	1	hSpCas9	negative selection	6669152
2054286	2054309	16	+	27260156	HS294T	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.30705034109805185	[684]	[467,248,261,317]	4	hSpCas9	negative selection	6669153
2050435	2050458	16	-	27260156	HS294T	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.9479616093079659	[1540]	[915,1185,1020,1560]	9	hSpCas9	negative selection	6669154
2047832	2047855	16	-	27260156	HS294T	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.408397210428717	[240]	[50,82,37,117]	-5	hSpCas9	negative selection	6714475
2050416	2050439	16	+	27260156	HS294T	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.31605936443036664	[948]	[447,477,436,463]	4	hSpCas9	negative selection	6733401
2054354	2054377	16	+	27260156	HS294T	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.4169475331766654	[338]	[95,182,201,235]	5	hSpCas9	negative selection	6733402
2053340	2053363	16	+	27260156	HS294T	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.63765343562928	[566]	[231,223,449,497]	8	hSpCas9	negative selection	6733403
2047803	2047826	16	-	27260156	HCC44	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6947344180700933	[151]	[323,182,481,177]	9	hSpCas9	negative selection	6771468
2053368	2053391	16	+	27260156	HCC44	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.10920058828788794	[416]	[748,363,432,513]	1	hSpCas9	negative selection	6790403
2054286	2054309	16	+	27260156	HCC44	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.35389205447428296	[684]	[841,781,1277,1111]	6	hSpCas9	negative selection	6790404
2050435	2050458	16	-	27260156	HCC44	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.21986673445806337	[1540]	[2596,1790,2487,1411]	3	hSpCas9	negative selection	6790405
2047832	2047855	16	-	27260156	HCC44	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.2117370781544875	[240]	[163,222,377,498]	3	hSpCas9	negative selection	6835726
2050416	2050439	16	+	27260156	HCC44	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.04984321149452686	[948]	[1059,794,948,1345]	-1	hSpCas9	negative selection	6854652
2054354	2054377	16	+	27260156	HCC44	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.040761968691313155	[338]	[424,340,520,321]	0	hSpCas9	negative selection	6854653
2053340	2053363	16	+	27260156	HCC44	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.19795728699231988	[566]	[751,473,598,446]	-3	hSpCas9	negative selection	6854654
2047803	2047826	16	-	27260156	G402	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.31416721661030667	[151]	[309,155,324,141]	4	hSpCas9	negative selection	6892719
2053368	2053391	16	+	27260156	G402	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.10720468569238124	[416]	[595,631,574,405]	1	hSpCas9	negative selection	6911654
2054286	2054309	16	+	27260156	G402	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.6198374877940921	[684]	[1591,1506,1164,942]	7	hSpCas9	negative selection	6911655
2050435	2050458	16	-	27260156	G402	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.3182019002548151	[1540]	[2496,2367,2442,2095]	4	hSpCas9	negative selection	6911656
2047832	2047855	16	-	27260156	G402	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.558778576612406	[240]	[673,442,547,116]	7	hSpCas9	negative selection	6956977
2050416	2050439	16	+	27260156	G402	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.464993576520089	[948]	[1461,2228,1343,1379]	6	hSpCas9	negative selection	6975903
2054354	2054377	16	+	27260156	G402	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.1057391400586637	[338]	[266,404,412,432]	-1	hSpCas9	negative selection	6975904
2053340	2053363	16	+	27260156	G402	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.24651963935965737	[566]	[1200,950,424,767]	3	hSpCas9	negative selection	6975905
2047803	2047826	16	-	27260156	L33	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.47286637397757225	[151]	[214,63,182,181]	8	hSpCas9	negative selection	7013970
2053368	2053391	16	+	27260156	L33	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.0830233174710582	[416]	[355,194,316,432]	1	hSpCas9	negative selection	7032905
2054286	2054309	16	+	27260156	L33	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.05144330885618609	[684]	[743,336,392,646]	1	hSpCas9	negative selection	7032906
2050435	2050458	16	-	27260156	L33	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.5655387323037886	[1540]	[2518,884,1352,2283]	9	hSpCas9	negative selection	7032907
2047832	2047855	16	-	27260156	L33	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.7954715810460824	[240]	[132,51,72,178]	-9	hSpCas9	negative selection	7078228
2050416	2050439	16	+	27260156	L33	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.5907781020755396	[948]	[1344,609,878,1485]	9	hSpCas9	negative selection	7097154
2054354	2054377	16	+	27260156	L33	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.0029939465941837	[338]	[838,276,378,595]	9	hSpCas9	negative selection	7097155
2053340	2053363	16	+	27260156	L33	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.08329436846006893	[566]	[750,277,316,465]	1	hSpCas9	negative selection	7097156
2047803	2047826	16	-	27260156	K562	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.31451687852744303	[151]	[188,182,181,123]	4	hSpCas9	negative selection	7135221
2053368	2053391	16	+	27260156	K562	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.16418381300315749	[416]	[380,647,322,324]	2	hSpCas9	negative selection	7154156
2054286	2054309	16	+	27260156	K562	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.35907013008494826	[684]	[1245,635,672,610]	4	hSpCas9	negative selection	7154157
2050435	2050458	16	-	27260156	K562	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.06603549609746029	[1540]	[1198,1608,1273,1161]	-1	hSpCas9	negative selection	7154158
2047832	2047855	16	-	27260156	K562	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.07198898152818312	[240]	[160,137,104,380]	-1	hSpCas9	negative selection	7199479
2050416	2050439	16	+	27260156	K562	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.3212411568905348	[948]	[1071,372,806,480]	-4	hSpCas9	negative selection	7218405
2054354	2054377	16	+	27260156	K562	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-1.0274490928859386	[338]	[44,108,142,267]	-8	hSpCas9	negative selection	7218406
2053340	2053363	16	+	27260156	K562	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.7656755343093422	[566]	[346,143,346,335]	-7	hSpCas9	negative selection	7218407
2047803	2047826	16	-	27260156	HT29	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.3258282061400668	[151]	[285,207,139,285]	6	hSpCas9	negative selection	7256472
2053368	2053391	16	+	27260156	HT29	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.1396441247090502	[416]	[689,609,464,487]	2	hSpCas9	negative selection	7275407
2054286	2054309	16	+	27260156	HT29	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.12400325030372916	[684]	[1000,1123,823,722]	2	hSpCas9	negative selection	7275408
2050435	2050458	16	-	27260156	HT29	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.2342710749792627	[1540]	[2119,2366,2494,1865]	4	hSpCas9	negative selection	7275409
2047832	2047855	16	-	27260156	HT29	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.092606170503855	[240]	[305,278,313,208]	-2	hSpCas9	negative selection	7320730
2050416	2050439	16	+	27260156	HT29	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.16857060953377823	[948]	[1584,1687,1033,966]	3	hSpCas9	negative selection	7339656
2054354	2054377	16	+	27260156	HT29	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.10448609601332015	[338]	[307,422,547,263]	-2	hSpCas9	negative selection	7339657
2053340	2053363	16	+	27260156	HT29	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.10560993216880687	[566]	[640,1000,640,342]	-2	hSpCas9	negative selection	7339658
2047803	2047826	16	-	27260156	MHHES1	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.7926511222537392	[151]	[198,275,363,320]	9	hSpCas9	negative selection	7377723
2053368	2053391	16	+	27260156	MHHES1	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.5122459104600758	[416]	[678,732,731,554]	8	hSpCas9	negative selection	7396658
2054286	2054309	16	+	27260156	MHHES1	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.21509994548722577	[684]	[1025,1090,871,662]	4	hSpCas9	negative selection	7396659
2050435	2050458	16	-	27260156	MHHES1	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	1.3874713966008134	[1540]	[4632,5031,4281,4239]	9	hSpCas9	negative selection	7396660
2047832	2047855	16	-	27260156	MHHES1	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.06688434734589	[240]	[414,299,197,243]	1	hSpCas9	negative selection	7441981
2050416	2050439	16	+	27260156	MHHES1	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	1.5668457837322756	[948]	[3721,3664,3045,2446]	9	hSpCas9	negative selection	7460907
2054354	2054377	16	+	27260156	MHHES1	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.6496536069784515	[338]	[1001,1670,1308,881]	9	hSpCas9	negative selection	7460908
2053340	2053363	16	+	27260156	MHHES1	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	1.503976480065921	[566]	[1853,2091,1780,1566]	9	hSpCas9	negative selection	7460909
2047803	2047826	16	-	27260156	MEWO	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.5746722808588196	[151]	[174,252,199]	9	hSpCas9	negative selection	7498974
2053368	2053391	16	+	27260156	MEWO	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.5084714863729131	[416]	[746,350,604]	8	hSpCas9	negative selection	7517909
2054286	2054309	16	+	27260156	MEWO	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.13711665944964524	[684]	[932,567,657]	3	hSpCas9	negative selection	7517910
2050435	2050458	16	-	27260156	MEWO	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.6668778436428384	[1540]	[2769,2160,2028]	9	hSpCas9	negative selection	7517911
2047832	2047855	16	-	27260156	MEWO	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.150489901843181	[240]	[173,239,321]	3	hSpCas9	negative selection	7563232
2050416	2050439	16	+	27260156	MEWO	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.6283010485118832	[948]	[1574,1188,1392]	9	hSpCas9	negative selection	7582158
2054354	2054377	16	+	27260156	MEWO	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.0917568053927633	[338]	[684,571,772]	9	hSpCas9	negative selection	7582159
2053340	2053363	16	+	27260156	MEWO	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.5827584065215297	[566]	[792,584,1005]	9	hSpCas9	negative selection	7582160
2047803	2047826	16	-	27260156	LNCAPCLONEFGC	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6225177799834385	[151]	[239,172,192,240]	8	hSpCas9	negative selection	7620225
2053368	2053391	16	+	27260156	LNCAPCLONEFGC	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.20406901023010812	[416]	[405,618,423,277]	3	hSpCas9	negative selection	7639160
2054286	2054309	16	+	27260156	LNCAPCLONEFGC	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.6015213176607296	[684]	[946,1015,810,966]	8	hSpCas9	negative selection	7639161
2050435	2050458	16	-	27260156	LNCAPCLONEFGC	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.035714954087095574	[1540]	[1480,1318,1558,1116]	0	hSpCas9	negative selection	7639162
2047832	2047855	16	-	27260156	LNCAPCLONEFGC	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.09031490735769498	[240]	[257,192,279,99]	-1	hSpCas9	negative selection	7684483
2050416	2050439	16	+	27260156	LNCAPCLONEFGC	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.18987903733723366	[948]	[763,757,796,700]	-3	hSpCas9	negative selection	7703409
2054354	2054377	16	+	27260156	LNCAPCLONEFGC	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.9714104063107196	[338]	[132,133,167,194]	-8	hSpCas9	negative selection	7703410
2053340	2053363	16	+	27260156	LNCAPCLONEFGC	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.692439363346629	[566]	[251,358,373,292]	-8	hSpCas9	negative selection	7703411
2047803	2047826	16	-	27260156	PANC0327	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.186953735601598	[151]	[179,77,297,70]	2	hSpCas9	negative selection	7741476
2053368	2053391	16	+	27260156	PANC0327	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.21202596295501625	[416]	[248,211,287,537]	-3	hSpCas9	negative selection	7760411
2054286	2054309	16	+	27260156	PANC0327	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.920203731348895	[684]	[670,1075,1726,1102]	9	hSpCas9	negative selection	7760412
2050435	2050458	16	-	27260156	PANC0327	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.46365340330553506	[1540]	[1184,916,625,1266]	-6	hSpCas9	negative selection	7760413
2047832	2047855	16	-	27260156	PANC0327	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.47955566525564564	[240]	[127,254,161,53]	-6	hSpCas9	negative selection	7805734
2050416	2050439	16	+	27260156	PANC0327	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.9813550603926531	[948]	[702,284,496,263]	-8	hSpCas9	negative selection	7824660
2054354	2054377	16	+	27260156	PANC0327	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.14407964092256176	[338]	[300,413,198,159]	-2	hSpCas9	negative selection	7824661
2053340	2053363	16	+	27260156	PANC0327	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.5025108592030176	[566]	[492,145,245,574]	-6	hSpCas9	negative selection	7824662
2047803	2047826	16	-	27260156	NCIH2009	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	1.4234421747610508	[151]	[672,532,522]	9	hSpCas9	negative selection	7862727
2053368	2053391	16	+	27260156	NCIH2009	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.2154121279948597	[416]	[749,714,576]	3	hSpCas9	negative selection	7881662
2054286	2054309	16	+	27260156	NCIH2009	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.7417633543491357	[684]	[1810,1275,1758]	8	hSpCas9	negative selection	7881663
2050435	2050458	16	-	27260156	NCIH2009	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.4037028150535067	[1540]	[3865,2242,2642]	5	hSpCas9	negative selection	7881664
2047832	2047855	16	-	27260156	NCIH2009	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.0833028656466448	[240]	[385,376,311]	1	hSpCas9	negative selection	7926985
2050416	2050439	16	+	27260156	NCIH2009	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.1906448640962659	[948]	[1762,1427,1396]	2	hSpCas9	negative selection	7945911
2054354	2054377	16	+	27260156	NCIH2009	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.12094139433112394	[338]	[478,462,371]	-2	hSpCas9	negative selection	7945912
2053340	2053363	16	+	27260156	NCIH2009	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.17131243931128054	[566]	[999,641,526]	-2	hSpCas9	negative selection	7945913
2047803	2047826	16	-	27260156	NCIH1373	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	1.2603558334735694	[151]	[613,307,432,81]	9	hSpCas9	negative selection	7983978
2053368	2053391	16	+	27260156	NCIH1373	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.48193459953716894	[416]	[1278,287,522,172]	5	hSpCas9	negative selection	8002913
2054286	2054309	16	+	27260156	NCIH1373	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.8144410458293382	[684]	[1689,1082,1169,406]	7	hSpCas9	negative selection	8002914
2050435	2050458	16	-	27260156	NCIH1373	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.08628266924051742	[1540]	[1862,1774,1890,473]	0	hSpCas9	negative selection	8002915
2047832	2047855	16	-	27260156	NCIH1373	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.25853196592132743	[240]	[341,226,96,67]	-3	hSpCas9	negative selection	8048236
2050416	2050439	16	+	27260156	NCIH1373	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.09274197203843115	[948]	[857,1336,374,365]	-1	hSpCas9	negative selection	8067162
2054354	2054377	16	+	27260156	NCIH1373	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-1.8834780163872735	[338]	[254,85,47,11]	-9	hSpCas9	negative selection	8067163
2053340	2053363	16	+	27260156	NCIH1373	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.8458806169568774	[566]	[181,263,460,129]	-7	hSpCas9	negative selection	8067164
2047803	2047826	16	-	27260156	PATU8902	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.9576076812294251	[151]	[723,237,309,387]	9	hSpCas9	negative selection	8105229
2053368	2053391	16	+	27260156	PATU8902	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.1971030107156309	[416]	[309,947,494,993]	2	hSpCas9	negative selection	8124164
2054286	2054309	16	+	27260156	PATU8902	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.8583502588584048	[684]	[2142,1855,1597,1282]	8	hSpCas9	negative selection	8124165
2050435	2050458	16	-	27260156	PATU8902	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	-0.39390434044924394	[1540]	[1517,1521,1504,2060]	-4	hSpCas9	negative selection	8124166
2047832	2047855	16	-	27260156	PATU8902	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.12778401519860716	[240]	[377,360,439,251]	1	hSpCas9	negative selection	8169487
2050416	2050439	16	+	27260156	PATU8902	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.9667563073101352	[948]	[761,594,498,916]	-7	hSpCas9	negative selection	8188413
2054354	2054377	16	+	27260156	PATU8902	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-2.8870235046398594	[338]	[88,56,16,108]	-9	hSpCas9	negative selection	8188414
2053340	2053363	16	+	27260156	PATU8902	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.9449936916026273	[566]	[153,411,417,687]	-7	hSpCas9	negative selection	8188415
2047803	2047826	16	-	27260156	PANC1	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6085743203106742	[151]	[210,185,253,147]	8	hSpCas9	negative selection	8226480
2053368	2053391	16	+	27260156	PANC1	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.04224069052577689	[416]	[434,499,327,250]	0	hSpCas9	negative selection	8245415
2054286	2054309	16	+	27260156	PANC1	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.5618387865832967	[684]	[983,1046,940,571]	8	hSpCas9	negative selection	8245416
2050435	2050458	16	-	27260156	PANC1	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.7199422417720192	[1540]	[2454,2015,2498,1748]	9	hSpCas9	negative selection	8245417
2047832	2047855	16	-	27260156	PANC1	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.4038177360705588	[240]	[102,202,190,139]	-6	hSpCas9	negative selection	8290738
2050416	2050439	16	+	27260156	PANC1	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.43903196858411	[948]	[1113,1211,962,1128]	7	hSpCas9	negative selection	8309664
2054354	2054377	16	+	27260156	PANC1	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.8345678587812663	[338]	[504,1090,322,301]	9	hSpCas9	negative selection	8309665
2053340	2053363	16	+	27260156	PANC1	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.7027169775797593	[566]	[609,1100,1004,550]	9	hSpCas9	negative selection	8309666
2047803	2047826	16	-	27260156	PANC0813	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	1.0532077169909775	[151]	[195,417,261,576]	9	hSpCas9	negative selection	8347731
2053368	2053391	16	+	27260156	PANC0813	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.3413544662542539	[416]	[690,559,584,649]	5	hSpCas9	negative selection	8366666
2054286	2054309	16	+	27260156	PANC0813	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.42789649266107344	[684]	[1192,985,1192,972]	7	hSpCas9	negative selection	8366667
2050435	2050458	16	-	27260156	PANC0813	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.13544882951527137	[1540]	[1966,1962,2078,1941]	2	hSpCas9	negative selection	8366668
2047832	2047855	16	-	27260156	PANC0813	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.8469553060718136	[240]	[160,126,136,201]	-8	hSpCas9	negative selection	8411989
2050416	2050439	16	+	27260156	PANC0813	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	-0.22035685107056135	[948]	[925,904,1012,977]	-4	hSpCas9	negative selection	8430915
2054354	2054377	16	+	27260156	PANC0813	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.32397218440709896	[338]	[307,449,291,225]	-5	hSpCas9	negative selection	8430916
2053340	2053363	16	+	27260156	PANC0813	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.5907071156336305	[566]	[567,359,601,260]	-7	hSpCas9	negative selection	8430917
2047803	2047826	16	-	27260156	RDES	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6330541401619545	[151]	[173,296,250,390]	8	hSpCas9	negative selection	8468982
2053368	2053391	16	+	27260156	RDES	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.418926161927221	[416]	[478,602,689,845]	6	hSpCas9	negative selection	8487917
2054286	2054309	16	+	27260156	RDES	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.5167356920435157	[684]	[907,1054,1089,1536]	8	hSpCas9	negative selection	8487918
2050435	2050458	16	-	27260156	RDES	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.45622130289757723	[1540]	[1903,1994,2872,3168]	7	hSpCas9	negative selection	8487919
2047832	2047855	16	-	27260156	RDES	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.14489653784754564	[240]	[309,197,359,368]	2	hSpCas9	negative selection	8533240
2050416	2050439	16	+	27260156	RDES	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.20501938781803064	[948]	[1051,1108,1496,1429]	3	hSpCas9	negative selection	8552166
2054354	2054377	16	+	27260156	RDES	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.4740041947720205	[338]	[428,519,637,601]	7	hSpCas9	negative selection	8552167
2053340	2053363	16	+	27260156	RDES	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.17065232146133819	[566]	[564,672,785,970]	2	hSpCas9	negative selection	8552168
2047803	2047826	16	-	27260156	PC3	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.0056302203407330165	[151]	[139,135,184,144]	0	hSpCas9	negative selection	8590233
2053368	2053391	16	+	27260156	PC3	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.2481280226887876	[416]	[329,400,1074,418]	5	hSpCas9	negative selection	8609168
2054286	2054309	16	+	27260156	PC3	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.32720694721873733	[684]	[643,765,1294,893]	7	hSpCas9	negative selection	8609169
2050435	2050458	16	-	27260156	PC3	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.3825573240527558	[1540]	[1102,1694,3598,2496]	7	hSpCas9	negative selection	8609170
2047832	2047855	16	-	27260156	PC3	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.5013277817017896	[240]	[88,174,246,220]	-8	hSpCas9	negative selection	8654491
2050416	2050439	16	+	27260156	PC3	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.42093651895852324	[948]	[640,1352,2114,1461]	8	hSpCas9	negative selection	8673417
2054354	2054377	16	+	27260156	PC3	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.005106746308122	[338]	[391,770,1114,661]	9	hSpCas9	negative selection	8673418
2053340	2053363	16	+	27260156	PC3	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.17716796717505223	[566]	[520,272,1104,843]	4	hSpCas9	negative selection	8673419
2047803	2047826	16	-	27260156	PATU8988T	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.29244139510656386	[151]	[151,166,147,257]	5	hSpCas9	negative selection	8711484
2053368	2053391	16	+	27260156	PATU8988T	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.20649091041023943	[416]	[419,617,316,525]	3	hSpCas9	negative selection	8730419
2054286	2054309	16	+	27260156	PATU8988T	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.26457869803901535	[684]	[755,817,923,672]	4	hSpCas9	negative selection	8730420
2050435	2050458	16	-	27260156	PATU8988T	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.9927293744240406	[1540]	[3359,3011,2583,2900]	9	hSpCas9	negative selection	8730421
2047832	2047855	16	-	27260156	PATU8988T	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.8679694145159325	[240]	[46,153,56,266]	-8	hSpCas9	negative selection	8775742
2050416	2050439	16	+	27260156	PATU8988T	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	1.094316232613781	[948]	[2029,1599,2298,1855]	9	hSpCas9	negative selection	8794668
2054354	2054377	16	+	27260156	PATU8988T	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	1.861604092263121	[338]	[1346,1209,605,1644]	9	hSpCas9	negative selection	8794669
2053340	2053363	16	+	27260156	PATU8988T	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	1.0081189295543194	[566]	[571,1170,1207,1492]	9	hSpCas9	negative selection	8794670
2047803	2047826	16	-	27260156	T47D	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.3962567871395488	[151]	[170,230,235,295]	8	hSpCas9	negative selection	8832735
2053368	2053391	16	+	27260156	T47D	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.19270511425200293	[416]	[677,493,528,524]	4	hSpCas9	negative selection	8851670
2054286	2054309	16	+	27260156	T47D	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.2785539333023951	[684]	[1007,966,998,894]	6	hSpCas9	negative selection	8851671
2050435	2050458	16	-	27260156	T47D	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.38013547236334877	[1540]	[2463,2205,1977,2726]	7	hSpCas9	negative selection	8851672
2047832	2047855	16	-	27260156	T47D	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.22033442589239705	[240]	[371,240,398,301]	5	hSpCas9	negative selection	8896993
2050416	2050439	16	+	27260156	T47D	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.308648810597115	[948]	[1367,1277,1429,1408]	6	hSpCas9	negative selection	8915919
2054354	2054377	16	+	27260156	T47D	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.485968700573246	[338]	[653,520,538,499]	8	hSpCas9	negative selection	8915920
2053340	2053363	16	+	27260156	T47D	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.22510663533105724	[566]	[756,762,723,847]	5	hSpCas9	negative selection	8915921
2047803	2047826	16	-	27260156	SU8686	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.6536635558372536	[151]	[239,215,196,305]	9	hSpCas9	negative selection	8953986
2053368	2053391	16	+	27260156	SU8686	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.3904085095693263	[416]	[490,566,521,593]	6	hSpCas9	negative selection	8972921
2054286	2054309	16	+	27260156	SU8686	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.3776968766256261	[684]	[798,737,1041,994]	6	hSpCas9	negative selection	8972922
2050435	2050458	16	-	27260156	SU8686	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.2545414736487883	[1540]	[1675,1590,2024,2078]	4	hSpCas9	negative selection	8972923
2047832	2047855	16	-	27260156	SU8686	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.358925491098679	[240]	[208,155,264,103]	-5	hSpCas9	negative selection	9018244
2050416	2050439	16	+	27260156	SU8686	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.015049817659809284	[948]	[837,822,1145,1037]	0	hSpCas9	negative selection	9037170
2054354	2054377	16	+	27260156	SU8686	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	-0.18492007884156725	[338]	[301,252,306,328]	-3	hSpCas9	negative selection	9037171
2053340	2053363	16	+	27260156	SU8686	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.4641188835294251	[566]	[396,392,381,466]	-6	hSpCas9	negative selection	9037172
2047803	2047826	16	-	27260156	SKES1	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.42967253419269125	[151]	[271,237,214,113]	8	hSpCas9	negative selection	9075237
2053368	2053391	16	+	27260156	SKES1	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.12833964665969275	[416]	[502,472,334,506]	3	hSpCas9	negative selection	9094172
2054286	2054309	16	+	27260156	SKES1	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.22843580950476294	[684]	[995,815,839,594]	5	hSpCas9	negative selection	9094173
2050435	2050458	16	-	27260156	SKES1	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.3833944936119311	[1540]	[2435,2329,1969,1431]	7	hSpCas9	negative selection	9094174
2047832	2047855	16	-	27260156	SKES1	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.1023232230723935	[240]	[288,326,300,138]	2	hSpCas9	negative selection	9139495
2050416	2050439	16	+	27260156	SKES1	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.46383848920471316	[948]	[1518,1693,1052,1052]	8	hSpCas9	negative selection	9158421
2054354	2054377	16	+	27260156	SKES1	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.39497084204973515	[338]	[483,539,391,382]	7	hSpCas9	negative selection	9158422
2053340	2053363	16	+	27260156	SKES1	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	-0.018507497158855135	[566]	[595,692,516,455]	0	hSpCas9	negative selection	9158423
2047803	2047826	16	-	27260156	TOV112D	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.4170225297694192	[151]	[158,131,244,253]	7	hSpCas9	negative selection	9196488
2053368	2053391	16	+	27260156	TOV112D	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.16366498218917705	[416]	[363,596,299,627]	3	hSpCas9	negative selection	9215423
2054286	2054309	16	+	27260156	TOV112D	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.2924419290396242	[684]	[857,1102,780,687]	5	hSpCas9	negative selection	9215424
2050435	2050458	16	-	27260156	TOV112D	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.6086246764753598	[1540]	[2331,2559,2045,2515]	9	hSpCas9	negative selection	9215425
2047832	2047855	16	-	27260156	TOV112D	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.3779137774295446	[240]	[342,481,267,207]	7	hSpCas9	negative selection	9260746
2050416	2050439	16	+	27260156	TOV112D	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.43475890773111936	[948]	[1164,2193,1195,808]	7	hSpCas9	negative selection	9279672
2054354	2054377	16	+	27260156	TOV112D	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.6266970230185318	[338]	[527,843,311,491]	9	hSpCas9	negative selection	9279673
2053340	2053363	16	+	27260156	TOV112D	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.13788681918410806	[566]	[658,765,452,656]	2	hSpCas9	negative selection	9279674
2047803	2047826	16	-	27260156	TC71	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.21479036530527762	[151]	[175,181,178,221]	5	hSpCas9	negative selection	9317739
2053368	2053391	16	+	27260156	TC71	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.06318607410004598	[416]	[488,435,417,529]	1	hSpCas9	negative selection	9336674
2054286	2054309	16	+	27260156	TC71	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.18989444019224166	[684]	[787,842,780,947]	5	hSpCas9	negative selection	9336675
2050435	2050458	16	-	27260156	TC71	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	0.3780814043345837	[1540]	[1731,2222,2265,2385]	8	hSpCas9	negative selection	9336676
2047832	2047855	16	-	27260156	TC71	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	-0.12044056948939263	[240]	[185,139,322,303]	-3	hSpCas9	negative selection	9381997
2050416	2050439	16	+	27260156	TC71	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	0.4725148549696929	[948]	[1213,1517,1326,1605]	9	hSpCas9	negative selection	9400923
2054354	2054377	16	+	27260156	TC71	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	0.4414175996328398	[338]	[458,517,495,501]	8	hSpCas9	negative selection	9400924
2053340	2053363	16	+	27260156	TC71	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	0.16982868970089937	[566]	[622,693,738,677]	4	hSpCas9	negative selection	9400925
2047803	2047826	16	-	27260156	TC32	viability	GCATGACCGCCTTGAGCGCGAGG	TSC2	ENSG00000103197	0.5962351385638835	[151]	[156,199,339,186]	8	hSpCas9	negative selection	9438990
2053368	2053391	16	+	27260156	TC32	viability	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.6985085634494309	[416]	[681,371,718,854]	9	hSpCas9	negative selection	9457925
2054286	2054309	16	+	27260156	TC32	viability	TTGTCTTTAGGGCGAGCGTTTGG	TSC2	ENSG00000103197	0.47516541022128156	[684]	[772,490,1325,1201]	7	hSpCas9	negative selection	9457926
2050435	2050458	16	-	27260156	TC32	viability	CACAAATCTGCCCTATCATCCGG	TSC2	ENSG00000103197	1.827503606895663	[1540]	[5490,4123,6570,4607]	9	hSpCas9	negative selection	9457927
2047832	2047855	16	-	27260156	TC32	viability	CGCCGGGATGTGTAGTCCGCAGG	TSC2	ENSG00000103197	0.11224093379810507	[240]	[198,190,367,254]	2	hSpCas9	negative selection	9503248
2050416	2050439	16	+	27260156	TC32	viability	GTGGCCTCAACAATCGCATCCGG	TSC2	ENSG00000103197	2.5021788771063047	[948]	[4431,4085,6904,5259]	9	hSpCas9	negative selection	9522174
2054354	2054377	16	+	27260156	TC32	viability	CCAACGAAGACCTTCACGAAAGG	TSC2	ENSG00000103197	2.613557104970786	[338]	[1465,1775,2686,2008]	9	hSpCas9	negative selection	9522175
2053340	2053363	16	+	27260156	TC32	viability	AGCACGCAGTGGAAGCACTCTGG	TSC2	ENSG00000103197	2.8674731927108104	[566]	[3528,2811,6602,3272]	9	hSpCas9	negative selection	9522176
2048597	2048620	16	+	27869803	HPAFII	viability after 27 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.08521285091026809	[380]	[148,221,NaN]	0	hSpCas9	negative selection	9556059
2053368	2053391	16	+	27869803	HPAFII	viability after 27 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.761333010384361	[135]	[75,13,NaN]	-5	hSpCas9	negative selection	9556060
2054386	2054409	16	+	27869803	HPAFII	viability after 27 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.3315592551295738	[502]	[454,840,NaN]	9	hSpCas9	negative selection	9556061
2055489	2055512	16	+	27869803	HPAFII	viability after 27 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-1.1421784627383973	[207]	[48,49,NaN]	-7	hSpCas9	negative selection	9556062
2056222	2056245	16	-	27869803	HPAFII	viability after 27 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-1.4674024565347517	[393]	[111,43,NaN]	-7	hSpCas9	negative selection	9556063
2056721	2056744	16	-	27869803	HPAFII	viability after 27 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.6159664988049678	[564]	[285,116,NaN]	-4	hSpCas9	negative selection	9556064
2048597	2048620	16	+	27869803	HPAFII	viability after 15 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.046175128407878185	[380]	[489,380,NaN]	0	hSpCas9	negative selection	9638508
2053368	2053391	16	+	27869803	HPAFII	viability after 15 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.01036829810022466	[135]	[318,36,NaN]	0	hSpCas9	negative selection	9638509
2054386	2054409	16	+	27869803	HPAFII	viability after 15 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.9924835134919539	[502]	[1180,1009,NaN]	9	hSpCas9	negative selection	9638510
2055489	2055512	16	+	27869803	HPAFII	viability after 15 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-0.7552389121805936	[207]	[182,100,NaN]	-7	hSpCas9	negative selection	9638511
2056222	2056245	16	-	27869803	HPAFII	viability after 15 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-2.058532115395512	[393]	[121,88,NaN]	-9	hSpCas9	negative selection	9638512
2056721	2056744	16	-	27869803	HPAFII	viability after 15 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.27393368489889836	[564]	[783,326,NaN]	-3	hSpCas9	negative selection	9638513
2048597	2048620	16	+	27869803	ASPC1	viability after 36 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.22339405946507274	[892]	[392,427,47]	-2	hSpCas9	negative selection	9720957
2053368	2053391	16	+	27869803	ASPC1	viability after 36 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	1.381229410973831	[202]	[347,171,77]	9	hSpCas9	negative selection	9720958
2054386	2054409	16	+	27869803	ASPC1	viability after 36 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.5113577997932404	[1198]	[460,678,619]	5	hSpCas9	negative selection	9720959
2055489	2055512	16	+	27869803	ASPC1	viability after 36 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	0.7251199188771046	[399]	[590,43,123]	7	hSpCas9	negative selection	9720960
2056222	2056245	16	-	27869803	ASPC1	viability after 36 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-0.8991794404010297	[932]	[284,130,129]	-7	hSpCas9	negative selection	9720961
2056721	2056744	16	-	27869803	ASPC1	viability after 36 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.015533570310136247	[1318]	[838,347,266]	0	hSpCas9	negative selection	9720962
2048597	2048620	16	+	27869803	PATU8988S	viability after 35 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.22652371318405873	[682]	[472,169,NaN]	2	hSpCas9	negative selection	9803406
2053368	2053391	16	+	27869803	PATU8988S	viability after 35 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.8958528964469101	[232]	[20,79,NaN]	-7	hSpCas9	negative selection	9803407
2054386	2054409	16	+	27869803	PATU8988S	viability after 35 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.6880095724583254	[1052]	[789,575,NaN]	7	hSpCas9	negative selection	9803408
2055489	2055512	16	+	27869803	PATU8988S	viability after 35 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.7543663685065063	[323]	[329,550,NaN]	9	hSpCas9	negative selection	9803409
2056222	2056245	16	-	27869803	PATU8988S	viability after 35 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.9263838314233173	[766]	[623,549,NaN]	8	hSpCas9	negative selection	9803410
2056721	2056744	16	-	27869803	PATU8988S	viability after 35 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	1.766130568812776	[1456]	[1543,2449,NaN]	9	hSpCas9	negative selection	9803411
2048597	2048620	16	+	27869803	PATU8988S	viability after 31 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.26142912359916304	[682]	[358,284,NaN]	3	hSpCas9	negative selection	9885855
2053368	2053391	16	+	27869803	PATU8988S	viability after 31 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.02368259714011245	[232]	[64,124,NaN]	0	hSpCas9	negative selection	9885856
2054386	2054409	16	+	27869803	PATU8988S	viability after 31 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	0.5502476661467849	[1052]	[620,606,NaN]	6	hSpCas9	negative selection	9885857
2055489	2055512	16	+	27869803	PATU8988S	viability after 31 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	1.8126251422305568	[323]	[210,762,NaN]	9	hSpCas9	negative selection	9885858
2056222	2056245	16	-	27869803	PATU8988S	viability after 31 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	0.8892155074402459	[766]	[470,687,NaN]	8	hSpCas9	negative selection	9885859
2056721	2056744	16	-	27869803	PATU8988S	viability after 31 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	1.47247431442272	[1456]	[1100,2262,NaN]	9	hSpCas9	negative selection	9885860
2048597	2048620	16	+	27869803	HPAFII	viability after 35 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	-0.23623365595072027	[380]	[127,203,NaN]	-1	hSpCas9	negative selection	9968304
2053368	2053391	16	+	27869803	HPAFII	viability after 35 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	0.28653576616409804	[135]	[154,3,NaN]	1	hSpCas9	negative selection	9968305
2054386	2054409	16	+	27869803	HPAFII	viability after 35 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.4361499990616315	[502]	[443,964,NaN]	8	hSpCas9	negative selection	9968306
2055489	2055512	16	+	27869803	HPAFII	viability after 35 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-1.5300115440036062	[207]	[19,54,NaN]	-7	hSpCas9	negative selection	9968307
2056222	2056245	16	-	27869803	HPAFII	viability after 35 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-2.040697227709047	[393]	[63,30,NaN]	-7	hSpCas9	negative selection	9968308
2056721	2056744	16	-	27869803	HPAFII	viability after 35 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.30078451918808924	[564]	[282,174,NaN]	-2	hSpCas9	negative selection	9968309
2048597	2048620	16	+	27869803	HPAFII	viability after 31 days	TGGTGCGTCCTGGTCCACCATGG	TSC2	ENSG00000103197	0.28494268910173437	[380]	[204,320,NaN]	2	hSpCas9	negative selection	10050753
2053368	2053391	16	+	27869803	HPAFII	viability after 31 days	GGTCGCGGATCTGTTGCAGCCGG	TSC2	ENSG00000103197	-0.6172599009333255	[135]	[88,6,NaN]	-4	hSpCas9	negative selection	10050754
2054386	2054409	16	+	27869803	HPAFII	viability after 31 days	TTCAAGGCCCTCACAGACAATGG	TSC2	ENSG00000103197	1.1540367426343332	[502]	[453,817,NaN]	8	hSpCas9	negative selection	10050755
2055489	2055512	16	+	27869803	HPAFII	viability after 31 days	ACCTCGACGAGTACATCGCAAGG	TSC2	ENSG00000103197	-1.36790599527362	[207]	[27,63,NaN]	-7	hSpCas9	negative selection	10050756
2056222	2056245	16	-	27869803	HPAFII	viability after 31 days	CTCTATGTCCACAGAGGACGCGG	TSC2	ENSG00000103197	-1.8285131556101781	[393]	[67,55,NaN]	-8	hSpCas9	negative selection	10050757
2056721	2056744	16	-	27869803	HPAFII	viability after 31 days	TGACGTTGATGGTGCGACAGAGG	TSC2	ENSG00000103197	-0.2470753641328053	[564]	[326,201,NaN]	-2	hSpCas9	negative selection	10050758
2084251	2084274	16	+	28162770	P31FUJ	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	0.4093042034103863	[263]	[411]	4	hSpCas9	negative selection	10257851
2079343	2079366	16	+	28162770	P31FUJ	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	0.38749336941905815	[241]	[371]	4	hSpCas9	negative selection	10257852
2060672	2060695	16	+	28162770	P31FUJ	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	0.32607106743811687	[92]	[136]	3	hSpCas9	negative selection	10257853
2061963	2061986	16	+	28162770	P31FUJ	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.9936575865202611	[252]	[591]	9	hSpCas9	negative selection	10257854
2064301	2064324	16	+	28162770	P31FUJ	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.32492040640280995	[96]	[90]	-3	hSpCas9	negative selection	10257855
2065607	2065630	16	-	28162770	P31FUJ	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	0.1861503448678484	[183]	[245]	2	hSpCas9	negative selection	10257856
2070547	2070570	16	-	28162770	P31FUJ	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	0.8094718630697053	[453]	[934]	8	hSpCas9	negative selection	10257857
2071885	2071908	16	-	28162770	P31FUJ	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-0.695464140452526	[502]	[364]	-5	hSpCas9	negative selection	10257858
2072321	2072344	16	-	28162770	P31FUJ	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.3939075049666809	[264]	[236]	-4	hSpCas9	negative selection	10257859
2076125	2076148	16	+	28162770	P31FUJ	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.09086356580890675	[560]	[618]	-1	hSpCas9	negative selection	10257860
2084251	2084274	16	+	28162770	TF1	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10427217
2079343	2079366	16	+	28162770	TF1	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10427218
2060672	2060695	16	+	28162770	TF1	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10427219
2061963	2061986	16	+	28162770	TF1	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10427220
2064301	2064324	16	+	28162770	TF1	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10427221
2065607	2065630	16	-	28162770	TF1	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10427222
2070547	2070570	16	-	28162770	TF1	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	NaN	[NaN]	[275]	1	hSpCas9	negative selection	10427223
2071885	2071908	16	-	28162770	TF1	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10427224
2072321	2072344	16	-	28162770	TF1	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10427225
2076125	2076148	16	+	28162770	TF1	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	NaN	[NaN]	[239]	1	hSpCas9	negative selection	10427226
2084251	2084274	16	+	28162770	SKM1	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.03701458899285609	[64]	[111]	0	hSpCas9	negative selection	10596583
2079343	2079366	16	+	28162770	SKM1	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-1.9740047914670555	[59]	[26]	-8	hSpCas9	negative selection	10596584
2060672	2060695	16	+	28162770	SKM1	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-1.9289169019385173	[27]	[12]	-8	hSpCas9	negative selection	10596585
2061963	2061986	16	+	28162770	SKM1	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.6335566086088953	[85]	[97]	-5	hSpCas9	negative selection	10596586
2064301	2064324	16	+	28162770	SKM1	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.8544231757143832	[44]	[21]	-8	hSpCas9	negative selection	10596587
2065607	2065630	16	-	28162770	SKM1	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-1.6293566200796095	[55]	[31]	-8	hSpCas9	negative selection	10596588
2070547	2070570	16	-	28162770	SKM1	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.24614140440810162	[105]	[157]	-2	hSpCas9	negative selection	10596589
2071885	2071908	16	-	28162770	SKM1	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.4868175064323763	[129]	[40]	-9	hSpCas9	negative selection	10596590
2072321	2072344	16	-	28162770	SKM1	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.7992816215219218	[62]	[31]	-8	hSpCas9	negative selection	10596591
2076125	2076148	16	+	28162770	SKM1	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.35385286228359925	[119]	[165]	-3	hSpCas9	negative selection	10596592
2084251	2084274	16	+	28162770	SKM1	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.03701458899285609	[64]	[111]	0	hSpCas9	negative selection	10765949
2079343	2079366	16	+	28162770	SKM1	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-1.9740047914670555	[59]	[26]	-8	hSpCas9	negative selection	10765950
2060672	2060695	16	+	28162770	SKM1	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-1.9289169019385173	[27]	[12]	-8	hSpCas9	negative selection	10765951
2061963	2061986	16	+	28162770	SKM1	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.6335566086088953	[85]	[97]	-5	hSpCas9	negative selection	10765952
2064301	2064324	16	+	28162770	SKM1	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.8544231757143832	[44]	[21]	-8	hSpCas9	negative selection	10765953
2065607	2065630	16	-	28162770	SKM1	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-1.6293566200796095	[55]	[31]	-8	hSpCas9	negative selection	10765954
2070547	2070570	16	-	28162770	SKM1	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.24614140440810162	[105]	[157]	-2	hSpCas9	negative selection	10765955
2071885	2071908	16	-	28162770	SKM1	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.4868175064323763	[129]	[40]	-9	hSpCas9	negative selection	10765956
2072321	2072344	16	-	28162770	SKM1	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.7992816215219218	[62]	[31]	-8	hSpCas9	negative selection	10765957
2076125	2076148	16	+	28162770	SKM1	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.35385286228359925	[119]	[165]	-3	hSpCas9	negative selection	10765958
2084251	2084274	16	+	28162770	PL21	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	0.26900147263412433	[224]	[117]	2	hSpCas9	negative selection	10935315
2079343	2079366	16	+	28162770	PL21	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-0.878811726905502	[168]	[39]	-6	hSpCas9	negative selection	10935316
2060672	2060695	16	+	28162770	PL21	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-2.1217884803980422	[109]	[10]	-8	hSpCas9	negative selection	10935317
2061963	2061986	16	+	28162770	PL21	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.22626934631397377	[382]	[194]	2	hSpCas9	negative selection	10935318
2064301	2064324	16	+	28162770	PL21	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	0.2909050784125025	[153]	[81]	2	hSpCas9	negative selection	10935319
2065607	2065630	16	-	28162770	PL21	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-0.18000309434333794	[176]	[67]	-1	hSpCas9	negative selection	10935320
2070547	2070570	16	-	28162770	PL21	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.3411616574356965	[357]	[122]	-2	hSpCas9	negative selection	10935321
2071885	2071908	16	-	28162770	PL21	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-1.3082016046289235	[329]	[57]	-7	hSpCas9	negative selection	10935322
2072321	2072344	16	-	28162770	PL21	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.5310436270828798	[165]	[49]	-4	hSpCas9	negative selection	10935323
2076125	2076148	16	+	28162770	PL21	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.5891813847380223	[317]	[91]	-4	hSpCas9	negative selection	10935324
2084251	2084274	16	+	28162770	P31FUJ	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	0.4093042034103863	[263]	[411]	4	hSpCas9	negative selection	11104681
2079343	2079366	16	+	28162770	P31FUJ	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	0.38749336941905815	[241]	[371]	4	hSpCas9	negative selection	11104682
2060672	2060695	16	+	28162770	P31FUJ	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	0.32607106743811687	[92]	[136]	3	hSpCas9	negative selection	11104683
2061963	2061986	16	+	28162770	P31FUJ	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.9936575865202611	[252]	[591]	9	hSpCas9	negative selection	11104684
2064301	2064324	16	+	28162770	P31FUJ	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.32492040640280995	[96]	[90]	-3	hSpCas9	negative selection	11104685
2065607	2065630	16	-	28162770	P31FUJ	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	0.1861503448678484	[183]	[245]	2	hSpCas9	negative selection	11104686
2070547	2070570	16	-	28162770	P31FUJ	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	0.8094718630697053	[453]	[934]	8	hSpCas9	negative selection	11104687
2071885	2071908	16	-	28162770	P31FUJ	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-0.695464140452526	[502]	[364]	-5	hSpCas9	negative selection	11104688
2072321	2072344	16	-	28162770	P31FUJ	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.3939075049666809	[264]	[236]	-4	hSpCas9	negative selection	11104689
2076125	2076148	16	+	28162770	P31FUJ	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.09086356580890675	[560]	[618]	-1	hSpCas9	negative selection	11104690
2084251	2084274	16	+	28162770	OCIAML5	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.7386085210807131	[109]	[118]	-5	hSpCas9	negative selection	11274047
2079343	2079366	16	+	28162770	OCIAML5	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-2.139868881846733	[187]	[76]	-8	hSpCas9	negative selection	11274048
2060672	2060695	16	+	28162770	OCIAML5	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-5.758957166472515	[59]	[1]	-9	hSpCas9	negative selection	11274049
2061963	2061986	16	+	28162770	OCIAML5	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-3.003008468938736	[150]	[33]	-8	hSpCas9	negative selection	11274050
2064301	2064324	16	+	28162770	OCIAML5	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-2.741883653113574	[62]	[16]	-8	hSpCas9	negative selection	11274051
2065607	2065630	16	-	28162770	OCIAML5	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-2.0304038121225094	[128]	[56]	-8	hSpCas9	negative selection	11274052
2070547	2070570	16	-	28162770	OCIAML5	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-2.1038498417230818	[280]	[117]	-8	hSpCas9	negative selection	11274053
2071885	2071908	16	-	28162770	OCIAML5	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.8460427832362267	[238]	[59]	-8	hSpCas9	negative selection	11274054
2072321	2072344	16	-	28162770	OCIAML5	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-2.2047381891824673	[165]	[64]	-8	hSpCas9	negative selection	11274055
2076125	2076148	16	+	28162770	OCIAML5	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-2.1679708781235894	[238]	[95]	-8	hSpCas9	negative selection	11274056
2084251	2084274	16	+	28162770	EOL1	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.2218087587333734	[424]	[191]	-2	hSpCas9	negative selection	11443413
2079343	2079366	16	+	28162770	EOL1	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-2.1036491202601173	[309]	[37]	-8	hSpCas9	negative selection	11443414
2060672	2060695	16	+	28162770	EOL1	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-1.8828071504870696	[181]	[25]	-8	hSpCas9	negative selection	11443415
2061963	2061986	16	+	28162770	EOL1	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	0.4264784398155581	[595]	[421]	4	hSpCas9	negative selection	11443416
2064301	2064324	16	+	28162770	EOL1	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-0.8186768130673541	[307]	[91]	-5	hSpCas9	negative selection	11443417
2065607	2065630	16	-	28162770	EOL1	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-2.068362803643146	[405]	[50]	-8	hSpCas9	negative selection	11443418
2070547	2070570	16	-	28162770	EOL1	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.5017169831315633	[472]	[175]	-4	hSpCas9	negative selection	11443419
2071885	2071908	16	-	28162770	EOL1	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.196467629390831	[521]	[59]	-8	hSpCas9	negative selection	11443420
2072321	2072344	16	-	28162770	EOL1	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.7779082921690623	[357]	[54]	-8	hSpCas9	negative selection	11443421
2076125	2076148	16	+	28162770	EOL1	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.6500727849291625	[416]	[139]	-5	hSpCas9	negative selection	11443422
2084251	2084274	16	+	28162770	MOLM13	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-1.0550634569011528	[295]	[102]	-5	hSpCas9	negative selection	11612779
2079343	2079366	16	+	28162770	MOLM13	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-2.7572854804631963	[345]	[36]	-8	hSpCas9	negative selection	11612780
2060672	2060695	16	+	28162770	MOLM13	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-4.924428041234181	[125]	[2]	-9	hSpCas9	negative selection	11612781
2061963	2061986	16	+	28162770	MOLM13	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-2.0703976578039582	[516]	[88]	-7	hSpCas9	negative selection	11612782
2064301	2064324	16	+	28162770	MOLM13	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.9674967631260674	[237]	[43]	-7	hSpCas9	negative selection	11612783
2065607	2065630	16	-	28162770	MOLM13	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-3.9583753731575193	[343]	[15]	-9	hSpCas9	negative selection	11612784
2070547	2070570	16	-	28162770	MOLM13	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-1.149863054294247	[622]	[202]	-6	hSpCas9	negative selection	11612785
2071885	2071908	16	-	28162770	MOLM13	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-4.727570712004871	[512]	[13]	-9	hSpCas9	negative selection	11612786
2072321	2072344	16	-	28162770	MOLM13	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-4.403297152382261	[438]	[14]	-9	hSpCas9	negative selection	11612787
2076125	2076148	16	+	28162770	MOLM13	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-1.2272560369270005	[543]	[167]	-6	hSpCas9	negative selection	11612788
2084251	2084274	16	+	28162770	HEL	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-2.134242441013728	[328]	[47]	-8	hSpCas9	negative selection	11782145
2079343	2079366	16	+	28162770	HEL	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-3.027112566307312	[279]	[21]	-8	hSpCas9	negative selection	11782146
2060672	2060695	16	+	28162770	HEL	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-2.176688922357822	[119]	[16]	-8	hSpCas9	negative selection	11782147
2061963	2061986	16	+	28162770	HEL	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.7549165890502505	[439]	[166]	-5	hSpCas9	negative selection	11782148
2064301	2064324	16	+	28162770	HEL	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-2.785498165033346	[182]	[16]	-8	hSpCas9	negative selection	11782149
2065607	2065630	16	-	28162770	HEL	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-1.7937011440107111	[248]	[45]	-7	hSpCas9	negative selection	11782150
2070547	2070570	16	-	28162770	HEL	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-1.1081556007972515	[450]	[133]	-6	hSpCas9	negative selection	11782151
2071885	2071908	16	-	28162770	HEL	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-3.164616090057247	[349]	[24]	-9	hSpCas9	negative selection	11782152
2072321	2072344	16	-	28162770	HEL	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.8705222033666102	[313]	[54]	-7	hSpCas9	negative selection	11782153
2076125	2076148	16	+	28162770	HEL	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-1.707143324458007	[468]	[91]	-7	hSpCas9	negative selection	11782154
2084251	2084274	16	+	28162770	MV411	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.4915165964768849	[241]	[144]	-4	hSpCas9	negative selection	11951511
2079343	2079366	16	+	28162770	MV411	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-1.3294876308729626	[178]	[59]	-7	hSpCas9	negative selection	11951512
2060672	2060695	16	+	28162770	MV411	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-1.886418195952015	[78]	[17]	-8	hSpCas9	negative selection	11951513
2061963	2061986	16	+	28162770	MV411	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.34162934827111746	[351]	[233]	-3	hSpCas9	negative selection	11951514
2064301	2064324	16	+	28162770	MV411	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-1.8945814540896522	[127]	[28]	-8	hSpCas9	negative selection	11951515
2065607	2065630	16	-	28162770	MV411	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-1.3899923698325165	[307]	[98]	-7	hSpCas9	negative selection	11951516
2070547	2070570	16	-	28162770	MV411	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.4197397132265685	[342]	[215]	-3	hSpCas9	negative selection	11951517
2071885	2071908	16	-	28162770	MV411	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-1.1214614103167686	[358]	[138]	-6	hSpCas9	negative selection	11951518
2072321	2072344	16	-	28162770	MV411	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-1.5486315637283137	[190]	[54]	-7	hSpCas9	negative selection	11951519
2076125	2076148	16	+	28162770	MV411	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	0.02996061986044385	[292]	[251]	0	hSpCas9	negative selection	11951520
2084251	2084274	16	+	28162770	MONOMAC1	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.47103046488321426	[184]	[152]	-4	hSpCas9	negative selection	12120877
2079343	2079366	16	+	28162770	MONOMAC1	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-0.6648158084103709	[129]	[93]	-5	hSpCas9	negative selection	12120878
2060672	2060695	16	+	28162770	MONOMAC1	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-0.134301091711591	[44]	[46]	-1	hSpCas9	negative selection	12120879
2061963	2061986	16	+	28162770	MONOMAC1	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.7742636990011045	[278]	[186]	-6	hSpCas9	negative selection	12120880
2064301	2064324	16	+	28162770	MONOMAC1	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	0.7010835389212328	[65]	[122]	6	hSpCas9	negative selection	12120881
2065607	2065630	16	-	28162770	MONOMAC1	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-0.07871687987079234	[116]	[126]	0	hSpCas9	negative selection	12120882
2070547	2070570	16	-	28162770	MONOMAC1	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.03820955450057184	[231]	[258]	0	hSpCas9	negative selection	12120883
2071885	2071908	16	-	28162770	MONOMAC1	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-0.7917803685732951	[221]	[146]	-6	hSpCas9	negative selection	12120884
2072321	2072344	16	-	28162770	MONOMAC1	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.7728971406734576	[157]	[105]	-6	hSpCas9	negative selection	12120885
2076125	2076148	16	+	28162770	MONOMAC1	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	1.1643423985465322	[201]	[518]	8	hSpCas9	negative selection	12120886
2084251	2084274	16	+	28162770	OCIAML2	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	-0.8308053894864869	[42]	[133]	-5	hSpCas9	negative selection	12290243
2079343	2079366	16	+	28162770	OCIAML2	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	-3.3775204208506797	[44]	[23]	-9	hSpCas9	negative selection	12290244
2060672	2060695	16	+	28162770	OCIAML2	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-3.570165498793076	[14]	[6]	-9	hSpCas9	negative selection	12290245
2061963	2061986	16	+	28162770	OCIAML2	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.9270081199019046	[58]	[171]	-6	hSpCas9	negative selection	12290246
2064301	2064324	16	+	28162770	OCIAML2	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	-2.5320303699063045	[23]	[22]	-8	hSpCas9	negative selection	12290247
2065607	2065630	16	-	28162770	OCIAML2	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-2.6770807027095875	[29]	[25]	-9	hSpCas9	negative selection	12290248
2070547	2070570	16	-	28162770	OCIAML2	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.2516200433003656	[60]	[283]	-2	hSpCas9	negative selection	12290249
2071885	2071908	16	-	28162770	OCIAML2	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-2.9710588157516495	[57]	[40]	-9	hSpCas9	negative selection	12290250
2072321	2072344	16	-	28162770	OCIAML2	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-2.516433514855286	[31]	[30]	-8	hSpCas9	negative selection	12290251
2076125	2076148	16	+	28162770	OCIAML2	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-1.3381795292185117	[51]	[113]	-7	hSpCas9	negative selection	12290252
2084251	2084274	16	+	28162770	OCIAML3	viability	GGAGAAGTCGCTCCACGCGGAGG	TSC2	ENSG00000103197	2.504024442636364	[71]	[1232]	9	hSpCas9	negative selection	12459609
2079343	2079366	16	+	28162770	OCIAML3	viability	GTCACTGTGACGACAAGCGTGGG	TSC2	ENSG00000103197	0.9194015993719591	[61]	[353]	7	hSpCas9	negative selection	12459610
2060672	2060695	16	+	28162770	OCIAML3	viability	CATGGCATGTCCGAACGAGGTGG	TSC2	ENSG00000103197	-2.059671212672975	[28]	[20]	-8	hSpCas9	negative selection	12459611
2061963	2061986	16	+	28162770	OCIAML3	viability	GGAGAGATACTTTGAACTGGTGG	TSC2	ENSG00000103197	-0.4095830691867356	[76]	[174]	-3	hSpCas9	negative selection	12459612
2064301	2064324	16	+	28162770	OCIAML3	viability	GCAGCTCTCCCACATCCCCGAGG	TSC2	ENSG00000103197	0.5913474016877552	[30]	[140]	5	hSpCas9	negative selection	12459613
2065607	2065630	16	-	28162770	OCIAML3	viability	GATGACCAGAAGCCCCAGGACGG	TSC2	ENSG00000103197	-2.168701805591492	[69]	[46]	-8	hSpCas9	negative selection	12459614
2070547	2070570	16	-	28162770	OCIAML3	viability	GATGCTGCTCGCGATTGGCAGGG	TSC2	ENSG00000103197	-0.16104823304805693	[99]	[269]	-1	hSpCas9	negative selection	12459615
2071885	2071908	16	-	28162770	OCIAML3	viability	GAAGAGCAGGGAGTAGGGCACGG	TSC2	ENSG00000103197	-0.5940076403241632	[113]	[227]	-4	hSpCas9	negative selection	12459616
2072321	2072344	16	-	28162770	OCIAML3	viability	ACAGCTGGTCCACACTGCAAGGG	TSC2	ENSG00000103197	-0.11439813974923546	[70]	[197]	-1	hSpCas9	negative selection	12459617
2076125	2076148	16	+	28162770	OCIAML3	viability	GTGCCGCCTGCCCTTCCGGAAGG	TSC2	ENSG00000103197	-0.6734421078185681	[83]	[158]	-5	hSpCas9	negative selection	12459618