Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7276
• Symbol: TTR
• Description: transthyretin

DataSource: http://genomecrispr.dkfz.de/#!/results/TTR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
31595144	31595167	18	+	26472758	Jiyoye	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	1.2739088506424092	[33]	[61]	7	hSpCas9	negative selection	174944
31595157	31595180	18	+	26472758	Jiyoye	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.6574987355901132	[94]	[112]	5	hSpCas9	negative selection	174945
31591926	31591949	18	-	26472758	Jiyoye	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.7291034763932358	[307]	[384]	5	hSpCas9	negative selection	174946
31592987	31593010	18	+	26472758	Jiyoye	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.4260344087571893	[75]	[76]	3	hSpCas9	negative selection	174947
31592946	31592969	18	-	26472758	Jiyoye	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	-0.03453006823505056	[181]	[133]	0	hSpCas9	negative selection	174948
31595128	31595151	18	+	26472758	Jiyoye	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	1.161523053900316	[98]	[166]	7	hSpCas9	negative selection	174949
31592929	31592952	18	+	26472758	Jiyoye	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.22660313586405256	[50]	[44]	1	hSpCas9	negative selection	174950
31595234	31595257	18	+	26472758	Jiyoye	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.09749933025764668	[165]	[116]	0	hSpCas9	negative selection	174951
31592956	31592979	18	-	26472758	Jiyoye	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	-0.47601095351137657	[165]	[89]	-3	hSpCas9	negative selection	174952
31592972	31592995	18	-	26472758	Jiyoye	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.8926022086761152	[14]	[20]	6	hSpCas9	negative selection	174953
31595144	31595167	18	+	26472758	KBM7	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.4939765617495115	[264,272]	[145,208]	5	hSpCas9	negative selection	366062
31595157	31595180	18	+	26472758	KBM7	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.592529410841246	[377,408]	[215,339]	6	hSpCas9	negative selection	366063
31591926	31591949	18	-	26472758	KBM7	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.7123177944745676	[1499,1023]	[1152,783]	7	hSpCas9	negative selection	366064
31592987	31593010	18	+	26472758	KBM7	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.3746706903289331	[433,332]	[235,227]	4	hSpCas9	negative selection	366065
31592946	31592969	18	-	26472758	KBM7	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.2243538336621262	[641,641]	[930,509]	9	hSpCas9	negative selection	366066
31595128	31595151	18	+	26472758	KBM7	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.29138777945955513	[610,564]	[335,340]	3	hSpCas9	negative selection	366067
31592929	31592952	18	+	26472758	KBM7	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	1.0250094019689813	[244,145]	[227,142]	9	hSpCas9	negative selection	366068
31595234	31595257	18	+	26472758	KBM7	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.03476958406586317	[787,893]	[505,286]	0	hSpCas9	negative selection	366069
31592956	31592979	18	-	26472758	KBM7	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	-0.14660349845488524	[463,522]	[288,142]	-1	hSpCas9	negative selection	366070
31592972	31592995	18	-	26472758	KBM7	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.47268952593097424	[86,172]	[40,49]	-4	hSpCas9	negative selection	366071
31595144	31595167	18	+	26472758	Raji	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.5799406829772347	[218]	[33]	-4	hSpCas9	negative selection	557180
31595157	31595180	18	+	26472758	Raji	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	1.062989416015146	[230]	[111]	8	hSpCas9	negative selection	557181
31591926	31591949	18	-	26472758	Raji	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	1.1186107907968537	[511]	[257]	8	hSpCas9	negative selection	557182
31592987	31593010	18	+	26472758	Raji	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.6997255664603532	[129]	[48]	6	hSpCas9	negative selection	557183
31592946	31592969	18	-	26472758	Raji	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.0647391979651057	[205]	[99]	8	hSpCas9	negative selection	557184
31595128	31595151	18	+	26472758	Raji	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.6087813194556246	[307]	[108]	6	hSpCas9	negative selection	557185
31592929	31592952	18	+	26472758	Raji	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.05554460385398147	[169]	[40]	0	hSpCas9	negative selection	557186
31595234	31595257	18	+	26472758	Raji	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.9783664775114932	[338]	[154]	8	hSpCas9	negative selection	557187
31592956	31592979	18	-	26472758	Raji	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	1.3000286133159953	[160]	[91]	9	hSpCas9	negative selection	557188
31592972	31592995	18	-	26472758	Raji	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	1.1504522572654856	[32]	[16]	8	hSpCas9	negative selection	557189
31595144	31595167	18	+	26472758	K562	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.26844272452641404	[360]	[252]	-2	hSpCas9	negative selection	748298
31595157	31595180	18	+	26472758	K562	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.45325583911142847	[442]	[511]	3	hSpCas9	negative selection	748299
31591926	31591949	18	-	26472758	K562	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.1878351993000793	[1065]	[1024]	1	hSpCas9	negative selection	748300
31592987	31593010	18	+	26472758	K562	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-0.5361361350474423	[279]	[162]	-3	hSpCas9	negative selection	748301
31592946	31592969	18	-	26472758	K562	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.8015470201908773	[470]	[692]	6	hSpCas9	negative selection	748302
31595128	31595151	18	+	26472758	K562	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	-0.08088409400157193	[534]	[426]	0	hSpCas9	negative selection	748303
31592929	31592952	18	+	26472758	K562	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.6574285455983082	[177]	[236]	5	hSpCas9	negative selection	748304
31595234	31595257	18	+	26472758	K562	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.027405642988772794	[579]	[498]	0	hSpCas9	negative selection	748305
31592956	31592979	18	-	26472758	K562	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	-0.013774415097847714	[475]	[397]	0	hSpCas9	negative selection	748306
31592972	31592995	18	-	26472758	K562	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-1.0581440423539843	[110]	[44]	-5	hSpCas9	negative selection	748307
31593020	31593043	18	-	26627737	DLD1	viability	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.8074055630978639	[322]	[131,361,61]	7	hSpCas9	negative selection	801339
31595144	31595167	18	+	26627737	DLD1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.043900732121520125	[609]	[155,271,137]	0	hSpCas9	negative selection	801340
31595235	31595258	18	-	26627737	DLD1	viability	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	1.2553172522181086	[390]	[251,314,306]	9	hSpCas9	negative selection	801341
31598594	31598617	18	-	26627737	DLD1	viability	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.5590741131836898	[644]	[190,389,311]	5	hSpCas9	negative selection	801342
31598596	31598619	18	-	26627737	DLD1	viability	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.45760708236541536	[255]	[74,57,43]	-4	hSpCas9	negative selection	801343
31598648	31598671	18	+	26627737	DLD1	viability	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.3504808098260574	[135]	[66,115,137]	9	hSpCas9	negative selection	801344
31593020	31593043	18	-	26627737	GBM cells	viability after 5 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.2682916252030346	[264]	[110,124]	-4	hSpCas9	negative selection	883654
31595144	31595167	18	+	26627737	GBM cells	viability after 5 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.28277873263362213	[268]	[186,163]	4	hSpCas9	negative selection	883655
31595235	31595258	18	-	26627737	GBM cells	viability after 5 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.3057308673595612	[263]	[201,147]	5	hSpCas9	negative selection	883656
31598594	31598617	18	-	26627737	GBM cells	viability after 5 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.65079117845582	[230]	[173,214]	8	hSpCas9	negative selection	883657
31598596	31598619	18	-	26627737	GBM cells	viability after 5 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.08701093990259179	[101]	[54,47]	-1	hSpCas9	negative selection	883658
31598648	31598671	18	+	26627737	GBM cells	viability after 5 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.6929719743298319	[108]	[89,98]	8	hSpCas9	negative selection	883659
31593020	31593043	18	-	26627737	GBM cells	viability after 13 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.3933178441836934	[264]	[227,156]	5	hSpCas9	negative selection	965969
31595144	31595167	18	+	26627737	GBM cells	viability after 13 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.6653716683787501	[268]	[295,178]	7	hSpCas9	negative selection	965970
31595235	31595258	18	-	26627737	GBM cells	viability after 13 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.14544555863582298	[263]	[201,122]	1	hSpCas9	negative selection	965971
31598594	31598617	18	-	26627737	GBM cells	viability after 13 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	1.0769164002036369	[230]	[302,232]	9	hSpCas9	negative selection	965972
31598596	31598619	18	-	26627737	GBM cells	viability after 13 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.06582864197065552	[101]	[47,65]	0	hSpCas9	negative selection	965973
31598648	31598671	18	+	26627737	GBM cells	viability after 13 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.1386510847199045	[108]	[143,118]	9	hSpCas9	negative selection	965974
31593020	31593043	18	-	26627737	GBM cells	viability after 21 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.31160115695288404	[264]	[197,160]	3	hSpCas9	negative selection	1048284
31595144	31595167	18	+	26627737	GBM cells	viability after 21 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.7437722394244978	[268]	[262,227]	7	hSpCas9	negative selection	1048285
31595235	31595258	18	-	26627737	GBM cells	viability after 21 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.34706472585617476	[263]	[183,180]	3	hSpCas9	negative selection	1048286
31598594	31598617	18	-	26627737	GBM cells	viability after 21 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	1.2132494254584452	[230]	[314,268]	9	hSpCas9	negative selection	1048287
31598596	31598619	18	-	26627737	GBM cells	viability after 21 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-1.2686300862988242	[101]	[22,22]	-8	hSpCas9	negative selection	1048288
31598648	31598671	18	+	26627737	GBM cells	viability after 21 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.8416319559543359	[108]	[114,97]	8	hSpCas9	negative selection	1048289
31593020	31593043	18	-	26627737	RPE1	viability after 9 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.1139091444972641	[878]	[152,384]	-1	hSpCas9	negative selection	1130599
31595144	31595167	18	+	26627737	RPE1	viability after 9 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.09371591512552557	[1216]	[222,529]	0	hSpCas9	negative selection	1130600
31595235	31595258	18	-	26627737	RPE1	viability after 9 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	-0.2872223916932256	[993]	[261,245]	-2	hSpCas9	negative selection	1130601
31598594	31598617	18	-	26627737	RPE1	viability after 9 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	1.2307475990351149	[564]	[384,453]	7	hSpCas9	negative selection	1130602
31598596	31598619	18	-	26627737	RPE1	viability after 9 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.3130847089396078	[239]	[80,33]	-2	hSpCas9	negative selection	1130603
31598648	31598671	18	+	26627737	RPE1	viability after 9 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.8387688065905454	[583]	[89,117]	-6	hSpCas9	negative selection	1130604
31593020	31593043	18	-	26627737	RPE1	viability after 12 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.5303350688662637	[878]	[163,162]	-4	hSpCas9	negative selection	1212914
31595144	31595167	18	+	26627737	RPE1	viability after 12 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.07649437105493317	[1216]	[251,442]	0	hSpCas9	negative selection	1212915
31595235	31595258	18	-	26627737	RPE1	viability after 12 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	-0.8003734740610502	[993]	[113,194]	-5	hSpCas9	negative selection	1212916
31598594	31598617	18	-	26627737	RPE1	viability after 12 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.9982662406500256	[564]	[378,222]	6	hSpCas9	negative selection	1212917
31598596	31598619	18	-	26627737	RPE1	viability after 12 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-1.4172546697108004	[239]	[45,0]	-7	hSpCas9	negative selection	1212918
31598648	31598671	18	+	26627737	RPE1	viability after 12 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.4265226754186186	[583]	[90,143]	-3	hSpCas9	negative selection	1212919
31593020	31593043	18	-	26627737	RPE1	viability after 15 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.0557386222456837	[878]	[338,142]	0	hSpCas9	negative selection	1295229
31595144	31595167	18	+	26627737	RPE1	viability after 15 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.035688444556843724	[1216]	[287,381]	0	hSpCas9	negative selection	1295230
31595235	31595258	18	-	26627737	RPE1	viability after 15 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	-0.2893806907121316	[993]	[281,179]	-2	hSpCas9	negative selection	1295231
31598594	31598617	18	-	26627737	RPE1	viability after 15 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	1.6645048605612827	[564]	[750,270]	8	hSpCas9	negative selection	1295232
31598596	31598619	18	-	26627737	RPE1	viability after 15 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-1.7371747044795338	[239]	[27,12]	-8	hSpCas9	negative selection	1295233
31598648	31598671	18	+	26627737	RPE1	viability after 15 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.5562978138183887	[583]	[92,130]	-4	hSpCas9	negative selection	1295234
31593020	31593043	18	-	26627737	RPE1	viability after 18 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.6528241399786476	[878]	[190,107]	-4	hSpCas9	negative selection	1377544
31595144	31595167	18	+	26627737	RPE1	viability after 18 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.30044082366226543	[1216]	[388,420]	2	hSpCas9	negative selection	1377545
31595235	31595258	18	-	26627737	RPE1	viability after 18 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	-0.42724025530747556	[993]	[242,152]	-3	hSpCas9	negative selection	1377546
31598594	31598617	18	-	26627737	RPE1	viability after 18 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	1.5156357483508223	[564]	[638,218]	7	hSpCas9	negative selection	1377547
31598596	31598619	18	-	26627737	RPE1	viability after 18 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.5529814703859612	[239]	[62,23]	-3	hSpCas9	negative selection	1377548
31598648	31598671	18	+	26627737	RPE1	viability after 18 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-1.1866856802690209	[583]	[46,92]	-6	hSpCas9	negative selection	1377549
31593020	31593043	18	-	26627737	HeLa	viability after 8 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.07164665851507147	[398]	[163,234,100]	0	hSpCas9	negative selection	1459859
31595144	31595167	18	+	26627737	HeLa	viability after 8 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.4192330924623076	[577]	[278,142,163]	-4	hSpCas9	negative selection	1459860
31595235	31595258	18	-	26627737	HeLa	viability after 8 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.1302930422708075	[219]	[178,36,113]	1	hSpCas9	negative selection	1459861
31598594	31598617	18	-	26627737	HeLa	viability after 8 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.4302159423266536	[671]	[360,467,348]	4	hSpCas9	negative selection	1459862
31598596	31598619	18	-	26627737	HeLa	viability after 8 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.304701434390342	[130]	[141,84,191]	8	hSpCas9	negative selection	1459863
31598648	31598671	18	+	26627737	HeLa	viability after 8 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.258764386630863	[144]	[166,101,184]	8	hSpCas9	negative selection	1459864
31593020	31593043	18	-	26627737	HeLa	viability after 12 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.3335061778761749	[398]	[116,185,319]	3	hSpCas9	negative selection	1542174
31595144	31595167	18	+	26627737	HeLa	viability after 12 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.295889274122406	[577]	[201,193,187]	-3	hSpCas9	negative selection	1542175
31595235	31595258	18	-	26627737	HeLa	viability after 12 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.9828706572230702	[219]	[209,65,275]	7	hSpCas9	negative selection	1542176
31598594	31598617	18	-	26627737	HeLa	viability after 12 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.17676008481054895	[671]	[181,312,442]	1	hSpCas9	negative selection	1542177
31598596	31598619	18	-	26627737	HeLa	viability after 12 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.9064530737101938	[130]	[149,99,55]	7	hSpCas9	negative selection	1542178
31598648	31598671	18	+	26627737	HeLa	viability after 12 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.2412711170946622	[144]	[137,149,135]	8	hSpCas9	negative selection	1542179
31593020	31593043	18	-	26627737	HeLa	viability after 15 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.13017546112623335	[398]	[56,197,194]	-1	hSpCas9	negative selection	1624489
31595144	31595167	18	+	26627737	HeLa	viability after 15 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.33179277907275784	[577]	[134,197,231]	-3	hSpCas9	negative selection	1624490
31595235	31595258	18	-	26627737	HeLa	viability after 15 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	1.2191362162839134	[219]	[165,336,115]	8	hSpCas9	negative selection	1624491
31598594	31598617	18	-	26627737	HeLa	viability after 15 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.604587502412925	[671]	[132,431,708]	5	hSpCas9	negative selection	1624492
31598596	31598619	18	-	26627737	HeLa	viability after 15 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.1521471732813198	[130]	[48,97,216]	7	hSpCas9	negative selection	1624493
31598648	31598671	18	+	26627737	HeLa	viability after 15 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.3856934341637213	[144]	[131,176,153]	8	hSpCas9	negative selection	1624494
31593020	31593043	18	-	26627737	HeLa	viability after 18 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.1543861894623297	[398]	[34,161,194]	-1	hSpCas9	negative selection	1706804
31595144	31595167	18	+	26627737	HeLa	viability after 18 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.3204909215910865	[577]	[90,166,231]	-3	hSpCas9	negative selection	1706805
31595235	31595258	18	-	26627737	HeLa	viability after 18 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	1.2240497586664167	[219]	[107,284,115]	8	hSpCas9	negative selection	1706806
31598594	31598617	18	-	26627737	HeLa	viability after 18 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.578310355635355	[671]	[79,350,708]	5	hSpCas9	negative selection	1706807
31598596	31598619	18	-	26627737	HeLa	viability after 18 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.1584248710457996	[130]	[29,85,216]	7	hSpCas9	negative selection	1706808
31598648	31598671	18	+	26627737	HeLa	viability after 18 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.367225641945472	[144]	[93,134,153]	8	hSpCas9	negative selection	1706809
31593020	31593043	18	-	26627737	HCT116	viability after 6 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-1.2828722433650641	[388]	[28,22]	-6	hSpCas9	negative selection	1789119
31595144	31595167	18	+	26627737	HCT116	viability after 6 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.45652941887263654	[931]	[274,13]	-3	hSpCas9	negative selection	1789120
31595235	31595258	18	-	26627737	HCT116	viability after 6 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	-1.2856656218096345	[763]	[56,44]	-6	hSpCas9	negative selection	1789121
31598594	31598617	18	-	26627737	HCT116	viability after 6 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.6993826793260893	[1276]	[276,352]	4	hSpCas9	negative selection	1789122
31598596	31598619	18	-	26627737	HCT116	viability after 6 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.0992502715953432	[226]	[147,36]	6	hSpCas9	negative selection	1789123
31598648	31598671	18	+	26627737	HCT116	viability after 6 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.0390808663132365	[471]	[350,42]	5	hSpCas9	negative selection	1789124
31593020	31593043	18	-	26627737	HCT116	viability after 8 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.2270566879380624	[147]	[236,183,152]	8	hSpCas9	negative selection	1871434
31595144	31595167	18	+	26627737	HCT116	viability after 8 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.5779927794806871	[465]	[127,193,192]	-6	hSpCas9	negative selection	1871435
31595235	31595258	18	-	26627737	HCT116	viability after 8 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.9075264385067242	[185]	[152,142,278]	8	hSpCas9	negative selection	1871436
31598594	31598617	18	-	26627737	HCT116	viability after 8 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.014332936177932742	[648]	[484,175,423]	0	hSpCas9	negative selection	1871437
31598596	31598619	18	-	26627737	HCT116	viability after 8 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.6731093858562434	[69]	[155,122,90]	9	hSpCas9	negative selection	1871438
31598648	31598671	18	+	26627737	HCT116	viability after 8 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.7595253411096896	[130]	[102,118,143]	7	hSpCas9	negative selection	1871439
31593020	31593043	18	-	26627737	HCT116	viability after 9 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.6400898124177716	[388]	[205,126]	4	hSpCas9	negative selection	1953749
31595144	31595167	18	+	26627737	HCT116	viability after 9 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.3076920724757319	[931]	[271,144]	-2	hSpCas9	negative selection	1953750
31595235	31595258	18	-	26627737	HCT116	viability after 9 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.41033337442891044	[763]	[207,320]	3	hSpCas9	negative selection	1953751
31598594	31598617	18	-	26627737	HCT116	viability after 9 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	-0.7240901220214173	[1276]	[354,88]	-5	hSpCas9	negative selection	1953752
31598596	31598619	18	-	26627737	HCT116	viability after 9 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.3470834213359368	[226]	[323,19]	8	hSpCas9	negative selection	1953753
31598648	31598671	18	+	26627737	HCT116	viability after 9 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.5834802586511304	[471]	[63,99]	-4	hSpCas9	negative selection	1953754
31593020	31593043	18	-	26627737	HCT116	viability after 12 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.2740541024546086	[147]	[239,198,120]	8	hSpCas9	negative selection	2036064
31595144	31595167	18	+	26627737	HCT116	viability after 12 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.6610806705753395	[465]	[121,133,210]	-6	hSpCas9	negative selection	2036065
31595235	31595258	18	-	26627737	HCT116	viability after 12 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.6158031081375773	[185]	[177,112,154]	6	hSpCas9	negative selection	2036066
31598594	31598617	18	-	26627737	HCT116	viability after 12 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.15388172816825163	[648]	[402,366,365]	1	hSpCas9	negative selection	2036067
31598596	31598619	18	-	26627737	HCT116	viability after 12 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.4774687222411695	[69]	[76,79,151]	9	hSpCas9	negative selection	2036068
31598648	31598671	18	+	26627737	HCT116	viability after 12 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	1.3952089843721862	[130]	[270,125,136]	9	hSpCas9	negative selection	2036069
31593020	31593043	18	-	26627737	HCT116	viability after 15 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.4941433530878587	[147]	[281,245,195]	9	hSpCas9	negative selection	2118379
31595144	31595167	18	+	26627737	HCT116	viability after 15 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.8899479419478804	[465]	[235,113,94]	-7	hSpCas9	negative selection	2118380
31595235	31595258	18	-	26627737	HCT116	viability after 15 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	1.1438655876328994	[185]	[305,121,287]	8	hSpCas9	negative selection	2118381
31598594	31598617	18	-	26627737	HCT116	viability after 15 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.2604596904214105	[648]	[388,380,560]	2	hSpCas9	negative selection	2118382
31598596	31598619	18	-	26627737	HCT116	viability after 15 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.7382354371491355	[69]	[77,97,26]	6	hSpCas9	negative selection	2118383
31598648	31598671	18	+	26627737	HCT116	viability after 15 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.6058232472466558	[130]	[195,92,64]	5	hSpCas9	negative selection	2118384
31593020	31593043	18	-	26627737	HCT116	viability after 18 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.2751498556571013	[147]	[172,228,110]	8	hSpCas9	negative selection	2200694
31595144	31595167	18	+	26627737	HCT116	viability after 18 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.4904832053082715	[465]	[263,126,88]	-4	hSpCas9	negative selection	2200695
31595235	31595258	18	-	26627737	HCT116	viability after 18 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.8564549137020767	[185]	[124,104,266]	6	hSpCas9	negative selection	2200696
31598594	31598617	18	-	26627737	HCT116	viability after 18 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	-0.1428911677843182	[648]	[122,311,421]	-1	hSpCas9	negative selection	2200697
31598596	31598619	18	-	26627737	HCT116	viability after 18 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	1.749430867112566	[69]	[100,181,50]	9	hSpCas9	negative selection	2200698
31598648	31598671	18	+	26627737	HCT116	viability after 18 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.9967592567325703	[130]	[234,82,60]	7	hSpCas9	negative selection	2200699
31592972	31592995	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.18195519654366865	[3,3]	[4,3]	4	hSpCas9	positive selection	3030065
31591926	31591949	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.003370760617929125	[2,2]	[1,3]	0	hSpCas9	positive selection	3030066
31591965	31591988	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	-0.7223605914779907	[2,3]	[2,0]	-8	hSpCas9	positive selection	3030067
31593020	31593043	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.14009887072900462	[5,5]	[4,5]	3	hSpCas9	positive selection	3030068
31592972	31592995	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.12247717284610075	[3,3]	[4,1]	2	hSpCas9	positive selection	3097923
31591926	31591949	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.7202605626177343	[2,2]	[2,4]	9	hSpCas9	positive selection	3097924
31591965	31591988	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	0.23053913958150737	[2,2]	[3,1]	4	hSpCas9	positive selection	3097925
31593020	31593043	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.0341277240002692	[5,5]	[4,3]	0	hSpCas9	positive selection	3097926
31592929	31592952		+	24336571	A375	resistance to PLX after 7 days	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.24240937063834123	[3,3]	[2,2]	-7	hSpCas9	positive selection	3153472
31591932	31591955		-	24336571	A375	resistance to PLX after 7 days	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.07280337855573593	[10,8]	[7,9]	-2	hSpCas9	positive selection	3153473
31593004	31593027		+	24336571	A375	resistance to PLX after 7 days	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	0.15343144510036266	[15,15]	[16,17]	5	hSpCas9	positive selection	3153474
31591942	31591965		+	24336571	A375	resistance to PLX after 7 days	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	-0.21979130987320294	[4,3]	[3,3]	-6	hSpCas9	positive selection	3153475
31592929	31592952		+	24336571	A375	resistance to PLX after 14 days	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2680508772684236	[2,4]	[1,1]	2	hSpCas9	positive selection	3211265
31591932	31591955		-	24336571	A375	resistance to PLX after 14 days	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.0428734297767247	[8,10]	[3,4]	0	hSpCas9	positive selection	3211266
31593004	31593027		+	24336571	A375	resistance to PLX after 14 days	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	0.31958460570106095	[24,14]	[11,9]	3	hSpCas9	positive selection	3211267
31591942	31591965		+	24336571	A375	resistance to PLX after 14 days	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	0.16283637847286414	[4,3]	[1,2]	1	hSpCas9	positive selection	3211268
31592929	31592952		+	24336571	A375	viability after 7 days	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.6502760590973056	[1]	[3,3]	8	hSpCas9	negative selection	3269058
31591932	31591955		-	24336571	A375	viability after 7 days	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.32426192135884907	[12]	[10,8]	-4	hSpCas9	negative selection	3269059
31593004	31593027		+	24336571	A375	viability after 7 days	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	0.6234794747633556	[10]	[15,15]	8	hSpCas9	negative selection	3269060
31591942	31591965		+	24336571	A375	viability after 7 days	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	0.0920344959443189	[4]	[4,3]	1	hSpCas9	negative selection	3269061
31592929	31592952		+	24336571	A375	viability after 14 days	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.743556245656779	[1]	[2,4]	8	hSpCas9	negative selection	3326851
31591932	31591955		-	24336571	A375	viability after 14 days	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.2898053579962009	[12]	[8,10]	-3	hSpCas9	negative selection	3326852
31593004	31593027		+	24336571	A375	viability after 14 days	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	0.9497397990542001	[10]	[24,14]	9	hSpCas9	negative selection	3326853
31591942	31591965		+	24336571	A375	viability after 14 days	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	-0.0072982971270880714	[4]	[4,3]	0	hSpCas9	negative selection	3326854
31592917	31592940	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	-0.9275491314624489	[290,290]	[0,0]	-6	hSpCas9	positive selection	3399652
31595234	31595257	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.1177132199010895	[165,165]	[0,0]	0	hSpCas9	positive selection	3399653
31595141	31595164	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	4.384974034541795	[226,226]	[30,30]	9	hSpCas9	positive selection	3399654
31592972	31592995	18	-	26780180	HT29	viability (Avana library 4 designs)	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.330315187170131	[]	[]	-5	hSpCas9	negative selection	3468981
31591926	31591949	18	-	26780180	HT29	viability (Avana library 4 designs)	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.909706413316986	[]	[]	3	hSpCas9	negative selection	3468982
31591965	31591988	18	-	26780180	HT29	viability (Avana library 4 designs)	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	0.629033917388903	[]	[]	2	hSpCas9	negative selection	3468983
31593020	31593043	18	-	26780180	HT29	viability (Avana library 4 designs)	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.0524905110608275	[]	[]	-1	hSpCas9	negative selection	3468984
31591926	31591949	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	2.12445308295913	[]	[]	3	hSpCas9	negative selection	3573988
31591965	31591988	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	0.130953223711413	[]	[]	0	hSpCas9	negative selection	3573989
31593020	31593043	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.46839982987965	[]	[]	2	hSpCas9	negative selection	3573990
31592972	31592995	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	3.74140354868548	[]	[]	6	hSpCas9	negative selection	3573991
31591932	31591955	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	0.216523376448828	[]	[]	0	hSpCas9	negative selection	3573992
31592929	31592952	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	4.97364695958779	[]	[]	8	hSpCas9	negative selection	3573993
31591926	31591949	18	-	26780180	A375	viability (Avana lentiGuide)	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	3.49003103971187	[]	[]	3	hSpCas9	negative selection	3682647
31591965	31591988	18	-	26780180	A375	viability (Avana lentiGuide)	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	-6.99059757867314	[]	[]	-9	hSpCas9	negative selection	3682648
31593020	31593043	18	-	26780180	A375	viability (Avana lentiGuide)	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-7.34595313301673	[]	[]	-9	hSpCas9	negative selection	3682649
31592972	31592995	18	-	26780180	A375	viability (Avana lentiGuide)	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-2.52260731818977	[]	[]	-4	hSpCas9	negative selection	3682650
31591932	31591955	18	-	26780180	A375	viability (Avana lentiGuide)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-8.9677091411412	[]	[]	-9	hSpCas9	negative selection	3682651
31592929	31592952	18	+	26780180	A375	viability (Avana lentiGuide)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.138396146522584	[]	[]	0	hSpCas9	negative selection	3682652
31591926	31591949	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	-0.05045305375355065	[4]	[5,3]	-1	hSpCas9	positive selection	3791254
31591965	31591988	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	-0.041998448067148586	[4]	[5,2]	0	hSpCas9	positive selection	3791255
31593020	31593043	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.09694118095867918	[6]	[6,4]	-2	hSpCas9	positive selection	3791256
31592972	31592995	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.12912897198978968	[5]	[6,5]	3	hSpCas9	positive selection	3791257
31591932	31591955	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.05719593202017639	[4]	[4,3]	-1	hSpCas9	positive selection	3791258
31592929	31592952	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2741645922789902	[5]	[6,6]	7	hSpCas9	positive selection	3791259
31591926	31591949	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	-0.3295859092201897	[4]	[2,3]	-4	hSpCas9	positive selection	3899861
31591965	31591988	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCACAGAAACACTCACCGTAGGG	TTR	ENSG00000118271	-0.5972546817649091	[4]	[1,2]	-6	hSpCas9	positive selection	3899862
31593020	31593043	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.2880300599464231	[6]	[7,6]	7	hSpCas9	positive selection	3899863
31592972	31592995	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.37249927750863654	[5]	[5,6]	9	hSpCas9	positive selection	3899864
31591932	31591955	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	0.5572455397133369	[4]	[6,5]	9	hSpCas9	positive selection	3899865
31592929	31592952	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2088359332577195	[5]	[6,4]	5	hSpCas9	positive selection	3899866
31592929	31592952	18	+	26780180	A375	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.57449037369927	[]	[]	-9	hSpCas9	negative selection	4008992
31598641	31598664	18	-	26780180	A375	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.861228429950129	[]	[]	3	hSpCas9	negative selection	4008993
31595234	31595257	18	+	26780180	A375	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	1.30386431743161	[]	[]	7	hSpCas9	negative selection	4008994
31598595	31598618	18	-	26780180	A375	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.414362547911623	[]	[]	1	hSpCas9	negative selection	4008995
31595141	31595164	18	+	26780180	A375	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	1.27610770432592	[]	[]	7	hSpCas9	negative selection	4008996
31592917	31592940	18	-	26780180	A375	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.343152430748071	[]	[]	0	hSpCas9	negative selection	4008997
31592929	31592952	18	+	26780180	HT29	viability (GeCKOv2 library)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.935455979735932	[]	[]	4	hSpCas9	negative selection	4116958
31598641	31598664	18	-	26780180	HT29	viability (GeCKOv2 library)	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.472774525185386	[]	[]	1	hSpCas9	negative selection	4116959
31595234	31595257	18	+	26780180	HT29	viability (GeCKOv2 library)	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.929365469387439	[]	[]	4	hSpCas9	negative selection	4116960
31598595	31598618	18	-	26780180	HT29	viability (GeCKOv2 library)	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.453512817935765	[]	[]	1	hSpCas9	negative selection	4116961
31595141	31595164	18	+	26780180	HT29	viability (GeCKOv2 library)	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	1.51943088118788	[]	[]	7	hSpCas9	negative selection	4116962
31592917	31592940	18	-	26780180	HT29	viability (GeCKOv2 library)	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.437873701526654	[]	[]	1	hSpCas9	negative selection	4116963
31592929	31592952	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.2985108209227746	[3]	[1,0]	-6	hSpCas9	positive selection	4180109
31591932	31591955	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	-0.027868347706707763	[3]	[1,1]	0	hSpCas9	positive selection	4180110
31593004	31593027	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	0.2403772259327795	[4]	[3,3]	6	hSpCas9	positive selection	4180111
31591942	31591965	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	-0.37198753097403303	[2]	[0,0]	-7	hSpCas9	positive selection	4180112
31592929	31592952	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.05987576937505329	[2]	[0,0,1,0]	-1	hSpCas9	positive selection	4244131
31591932	31591955	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACAAATACCAGTCCAGCAAGG	TTR	ENSG00000118271	0.11552268367259272	[4]	[4,3,0,0]	0	hSpCas9	positive selection	4244132
31593004	31593027	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGGGAGCCATTTGCCTCTGG	TTR	ENSG00000118271	-0.2749721735858672	[3]	[0,3,0,0]	-4	hSpCas9	positive selection	4244133
31591942	31591965	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGTATTTGTGTCTGAGGCTGG	TTR	ENSG00000118271	-0.3863257115423996	[2]	[0,0,0,0]	-5	hSpCas9	positive selection	4244134
31598641	31598664	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.11299687265675773	[2]	[2,1]	-2	hSpCas9	positive selection	4305847
31598595	31598618	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.24942351620874392	[0]	[0,0]	-5	hSpCas9	positive selection	4305848
31592929	31592952	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3591961215915345	[3]	[3,2]	7	hSpCas9	positive selection	4305849
31592917	31592940	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.37692956982678893	[3]	[4,3]	7	hSpCas9	positive selection	4370096
31595234	31595257	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.11658889061611835	[2]	[3,0]	-2	hSpCas9	positive selection	4370097
31595141	31595164	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.047148484108688146	[3]	[3,2]	0	hSpCas9	positive selection	4370098
31592917	31592939	18	-	27760321	OCIAML3	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.6996742594045737	[378,278]	[341,507]	8	hSpCas9	negative selection	4451152
31592960	31592982	18	-	27760321	OCIAML3	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.6470125704760671	[706,522]	[590,948]	7	hSpCas9	negative selection	4451153
31592989	31593011	18	+	27760321	OCIAML3	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.979663711724817	[448,382]	[553,750]	9	hSpCas9	negative selection	4451154
31593020	31593042	18	-	27760321	OCIAML3	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.7849801472022879	[495,412]	[628,584]	8	hSpCas9	negative selection	4451155
31595159	31595181	18	+	27760321	OCIAML3	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	1.047968384600381	[75,52]	[93,114]	9	hSpCas9	negative selection	4451156
31592917	31592939	18	-	27760321	OCIAML2	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.42292567324968794	[378,278]	[296,427]	6	hSpCas9	negative selection	4534615
31592960	31592982	18	-	27760321	OCIAML2	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.3753475721917574	[706,522]	[601,688]	5	hSpCas9	negative selection	4534616
31592989	31593011	18	+	27760321	OCIAML2	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.6720299498398769	[448,382]	[445,650]	8	hSpCas9	negative selection	4534617
31593020	31593042	18	-	27760321	OCIAML2	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.7226374064562713	[495,412]	[494,747]	8	hSpCas9	negative selection	4534618
31595159	31595181	18	+	27760321	OCIAML2	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	-1.1826211889945997	[75,52]	[20,24]	-8	hSpCas9	negative selection	4534619
31592917	31592939	18	-	27760321	MV411	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	-0.4202874764994751	[378,278]	[97,254]	-3	hSpCas9	negative selection	4618078
31592960	31592982	18	-	27760321	MV411	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.731919656786754	[706,522]	[635,715]	5	hSpCas9	negative selection	4618079
31592989	31593011	18	+	27760321	MV411	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.7367562339118268	[448,382]	[200,838]	5	hSpCas9	negative selection	4618080
31593020	31593042	18	-	27760321	MV411	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.3150356420652474	[495,412]	[376,1292]	8	hSpCas9	negative selection	4618081
31595159	31595181	18	+	27760321	MV411	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.7169442371870245	[75,52]	[29,127]	5	hSpCas9	negative selection	4618082
31592917	31592939	18	-	27760321	HL60	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.19270119976076514	[378,278]	[447,151]	2	hSpCas9	negative selection	4701541
31592960	31592982	18	-	27760321	HL60	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.49221713341855633	[706,522]	[593,812]	6	hSpCas9	negative selection	4701542
31592989	31593011	18	+	27760321	HL60	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.9939624545942543	[448,382]	[545,810]	9	hSpCas9	negative selection	4701543
31593020	31593042	18	-	27760321	HL60	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.44638136744803186	[495,412]	[578,423]	5	hSpCas9	negative selection	4701544
31595159	31595181	18	+	27760321	HL60	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.22966805227125553	[75,52]	[13,110]	3	hSpCas9	negative selection	4701545
31592917	31592939	18	-	27760321	HT1080	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	2.0419160006401986	[278,217]	[400,414]	9	hSpCas9	negative selection	4785004
31592960	31592982	18	-	27760321	HT1080	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	1.7580943310213522	[522,407]	[684,563]	8	hSpCas9	negative selection	4785005
31592989	31593011	18	+	27760321	HT1080	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.14980350147609892	[382,298]	[112,191]	0	hSpCas9	negative selection	4785006
31593020	31593042	18	-	27760321	HT1080	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	2.0099506415029538	[412,321]	[686,482]	9	hSpCas9	negative selection	4785007
31595159	31595181	18	+	27760321	HT1080	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	2.212084268547638	[52,41]	[166,0]	9	hSpCas9	negative selection	4785008
31592917	31592939	18	-	27760321	HT29	viability after 7 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.6178528742647978	[278,217]	[727,438,341]	8	hSpCas9	negative selection	4868467
31592960	31592982	18	-	27760321	HT29	viability after 7 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.2377762993390774	[522,407]	[598,830,671]	3	hSpCas9	negative selection	4868468
31592989	31593011	18	+	27760321	HT29	viability after 7 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.19628618999532882	[382,298]	[741,408,392]	3	hSpCas9	negative selection	4868469
31593020	31593042	18	-	27760321	HT29	viability after 7 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.023212150654723804	[412,321]	[524,581,300]	0	hSpCas9	negative selection	4868470
31595159	31595181	18	+	27760321	HT29	viability after 7 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.208887956509193	[52,41]	[65,131,14]	3	hSpCas9	negative selection	4868471
31592917	31592939	18	-	27760321	HT29	viability after 25 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.9063860684671454	[278,217]	[399,650,555]	9	hSpCas9	negative selection	4951930
31592960	31592982	18	-	27760321	HT29	viability after 25 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.8746049862517651	[522,407]	[808,987,1156]	8	hSpCas9	negative selection	4951931
31592989	31593011	18	+	27760321	HT29	viability after 25 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.45859099905725426	[382,298]	[568,418,624]	5	hSpCas9	negative selection	4951932
31593020	31593042	18	-	27760321	HT29	viability after 25 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.4892933740602559	[412,321]	[416,612,766]	5	hSpCas9	negative selection	4951933
31595159	31595181	18	+	27760321	HT29	viability after 25 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.22608625826314555	[52,41]	[71,71,43]	2	hSpCas9	negative selection	4951934
31592917	31592939	18	-	27760321	HT29	viability after 22 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.8872692258883166	[278,217]	[525,677,388]	8	hSpCas9	negative selection	5035393
31592960	31592982	18	-	27760321	HT29	viability after 22 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.5813411845224881	[522,407]	[691,766,960]	6	hSpCas9	negative selection	5035394
31592989	31593011	18	+	27760321	HT29	viability after 22 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.635384945123258	[382,298]	[755,587,487]	7	hSpCas9	negative selection	5035395
31593020	31593042	18	-	27760321	HT29	viability after 22 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.3486629744739103	[412,321]	[469,589,564]	3	hSpCas9	negative selection	5035396
31595159	31595181	18	+	27760321	HT29	viability after 22 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	-1.0252961468540716	[52,41]	[24,35,19]	-6	hSpCas9	negative selection	5035397
31592917	31592939	18	-	27760321	HT29	viability after 19 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.5153024366701584	[278,217]	[592,372,276]	5	hSpCas9	negative selection	5118856
31592960	31592982	18	-	27760321	HT29	viability after 19 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.6724390891897678	[522,407]	[1049,883,639]	6	hSpCas9	negative selection	5118857
31592989	31593011	18	+	27760321	HT29	viability after 19 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.3913743143232114	[382,298]	[582,426,530]	4	hSpCas9	negative selection	5118858
31593020	31593042	18	-	27760321	HT29	viability after 19 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.6541482462137443	[412,321]	[897,811,311]	6	hSpCas9	negative selection	5118859
31595159	31595181	18	+	27760321	HT29	viability after 19 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	-0.6237746302808862	[52,41]	[18,72,12]	-5	hSpCas9	negative selection	5118860
31592917	31592939	18	-	27760321	HT29	viability after 16 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.36725709383469896	[278,217]	[405,333,340]	4	hSpCas9	negative selection	5202319
31592960	31592982	18	-	27760321	HT29	viability after 16 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.4272078253552656	[522,407]	[710,688,701]	5	hSpCas9	negative selection	5202320
31592989	31593011	18	+	27760321	HT29	viability after 16 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.3785981140894518	[382,298]	[718,495,293]	4	hSpCas9	negative selection	5202321
31593020	31593042	18	-	27760321	HT29	viability after 16 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.5810434799773991	[412,321]	[616,659,566]	6	hSpCas9	negative selection	5202322
31595159	31595181	18	+	27760321	HT29	viability after 16 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.2963250604646186	[52,41]	[60,47,86]	3	hSpCas9	negative selection	5202323
31592917	31592939	18	-	27760321	HT29	viability after 13 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.8057885112106707	[278,217]	[653,480,383]	9	hSpCas9	negative selection	5285782
31592960	31592982	18	-	27760321	HT29	viability after 13 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.6188632242926729	[522,407]	[777,951,761]	7	hSpCas9	negative selection	5285783
31592989	31593011	18	+	27760321	HT29	viability after 13 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.5962067278887148	[382,298]	[519,859,424]	7	hSpCas9	negative selection	5285784
31593020	31593042	18	-	27760321	HT29	viability after 13 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.19174226597957944	[412,321]	[530,603,334]	2	hSpCas9	negative selection	5285785
31595159	31595181	18	+	27760321	HT29	viability after 13 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	-0.1250397382255084	[52,41]	[26,94,30]	-1	hSpCas9	negative selection	5285786
31592917	31592939	18	-	27760321	HT29	viability after 10 days	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.8887811976732056	[278,217]	[620,703,405]	9	hSpCas9	negative selection	5369245
31592960	31592982	18	-	27760321	HT29	viability after 10 days	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.33716368398366203	[522,407]	[726,687,784]	4	hSpCas9	negative selection	5369246
31592989	31593011	18	+	27760321	HT29	viability after 10 days	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	0.4753251347239752	[382,298]	[487,785,508]	6	hSpCas9	negative selection	5369247
31593020	31593042	18	-	27760321	HT29	viability after 10 days	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.14855123548811283	[412,321]	[543,559,424]	2	hSpCas9	negative selection	5369248
31595159	31595181	18	+	27760321	HT29	viability after 10 days	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	0.1548885440735912	[52,41]	[83,112,3]	2	hSpCas9	negative selection	5369249
31592917	31592939	18	-	27760321	MOLM13	viability	CTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.7198088686241484	[378,278]	[236,358]	5	hSpCas9	negative selection	5452708
31592960	31592982	18	-	27760321	MOLM13	viability	ACATGCACGGCCACATTGATGG	TTR	ENSG00000118271	0.05836373225323688	[706,522]	[242,455]	0	hSpCas9	negative selection	5452709
31592989	31593011	18	+	27760321	MOLM13	viability	AAGGCTGCTGATGACACCTGGG	TTR	ENSG00000118271	1.2459957217949182	[448,382]	[347,730]	8	hSpCas9	negative selection	5452710
31593020	31593042	18	-	27760321	MOLM13	viability	TCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	1.0547760983827499	[495,412]	[678,403]	7	hSpCas9	negative selection	5452711
31595159	31595181	18	+	27760321	MOLM13	viability	TGAGGAGGAATTTGTAGAAGGG	TTR	ENSG00000118271	-0.47707459213048375	[75,52]	[0,46]	-3	hSpCas9	negative selection	5452712
31591880	31591903	18	+	27661255	K562	viability	GAAGTCCACTCATTCTTGGCAGG	TTR	ENSG00000118271	-0.028518362410430514	[879,892]	[719,671]	-1	dCas9-KRAB	negative selection	5520590
31592970	31592993	18	+	27661255	K562	viability	GGCCGTGCATGTGTTCAGAAAGG	TTR	ENSG00000118271	0.10271102684648392	[1916,1979]	[1888,1483]	3	dCas9-KRAB	negative selection	5520591
31593298	31593321	18	+	27661255	K562	viability	GGTCACAGAACACTTTATGTAGG	TTR	ENSG00000118271	0.23217563547894424	[538,631]	[543,550]	7	dCas9-KRAB	negative selection	5520592
31591872	31591895	18	-	27661255	K562	viability	GAATGAGTGGACTTCTGTGATGG	TTR	ENSG00000118271	0.327110394306934	[1057,1306]	[1234,1133]	9	dCas9-KRAB	negative selection	5520593
31598641	31598664	18	-	27260156	BXPC3	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.2942867058092764	[458]	[325,349,402,507]	-6	hSpCas9	negative selection	5578307
31598595	31598618	18	-	27260156	BXPC3	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.1799348401757208	[29]	[33,31,51,22]	4	hSpCas9	negative selection	5578308
31592929	31592952	18	+	27260156	BXPC3	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2867230083940763	[473]	[555,604,663,593]	6	hSpCas9	negative selection	5578309
31592917	31592940	18	-	27260156	BXPC3	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.44356209151842535	[624]	[1062,774,870,817]	8	hSpCas9	negative selection	5642556
31595234	31595257	18	+	27260156	BXPC3	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.34184791129787084	[421]	[596,527,531,574]	7	hSpCas9	negative selection	5642557
31595141	31595164	18	+	27260156	BXPC3	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.14246472173523442	[566]	[407,497,575,699]	-3	hSpCas9	negative selection	5642558
31598641	31598664	18	-	27260156	A673	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.12588888877061055	[458]	[536,458,435,597]	-3	hSpCas9	negative selection	5699558
31598595	31598618	18	-	27260156	A673	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.19011541402868692	[29]	[44,22,28,30]	-5	hSpCas9	negative selection	5699559
31592929	31592952	18	+	27260156	A673	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.18926512809653356	[473]	[797,708,525,573]	4	hSpCas9	negative selection	5699560
31592917	31592940	18	-	27260156	A673	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.3200209887381413	[624]	[1148,847,855,918]	7	hSpCas9	negative selection	5763807
31595234	31595257	18	+	27260156	A673	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.042432125018649416	[421]	[597,460,540,494]	1	hSpCas9	negative selection	5763808
31595141	31595164	18	+	27260156	A673	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.0594994520572977	[566]	[721,604,541,758]	-1	hSpCas9	negative selection	5763809
31598641	31598664	18	-	27260156	A375	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.054578606738251614	[458]	[444,853,497,477]	0	hSpCas9	negative selection	5820809
31598595	31598618	18	-	27260156	A375	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.008775213354508704	[29]	[68,44,11,16]	0	hSpCas9	negative selection	5820810
31592929	31592952	18	+	27260156	A375	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.49149562358345955	[473]	[728,971,833,620]	7	hSpCas9	negative selection	5820811
31592917	31592940	18	-	27260156	A375	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.5782401667379988	[624]	[1160,1456,893,915]	8	hSpCas9	negative selection	5885058
31595234	31595257	18	+	27260156	A375	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.4591794610867494	[421]	[818,766,593,555]	6	hSpCas9	negative selection	5885059
31595141	31595164	18	+	27260156	A375	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.19001876335925139	[566]	[487,1006,538,369]	-3	hSpCas9	negative selection	5885060
31598641	31598664	18	-	27260156	COLO741	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.12466034609224225	[458]	[667,623,627]	2	hSpCas9	negative selection	5942060
31598595	31598618	18	-	27260156	COLO741	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.1042079542889556	[29]	[6,19,24]	-9	hSpCas9	negative selection	5942061
31592929	31592952	18	+	27260156	COLO741	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.46624368674829164	[473]	[929,680,899]	8	hSpCas9	negative selection	5942062
31592917	31592940	18	-	27260156	COLO741	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.33978996812055634	[624]	[1125,1052,870]	7	hSpCas9	negative selection	6006309
31595234	31595257	18	+	27260156	COLO741	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.3718181939859573	[421]	[399,517,335]	-7	hSpCas9	negative selection	6006310
31595141	31595164	18	+	27260156	COLO741	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.04093513092521345	[566]	[836,619,781]	0	hSpCas9	negative selection	6006311
31598641	31598664	18	-	27260156	CAL120	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.04151312107729317	[458]	[575,456,725]	0	hSpCas9	negative selection	6063311
31598595	31598618	18	-	27260156	CAL120	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.41087475084154645	[29]	[35,70,39]	6	hSpCas9	negative selection	6063312
31592929	31592952	18	+	27260156	CAL120	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.1455620573664166	[473]	[698,494,767]	2	hSpCas9	negative selection	6063313
31592917	31592940	18	-	27260156	CAL120	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.2728550349846081	[624]	[882,982,943]	4	hSpCas9	negative selection	6127560
31595234	31595257	18	+	27260156	CAL120	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.04091632144874477	[421]	[661,552,341]	0	hSpCas9	negative selection	6127561
31595141	31595164	18	+	27260156	CAL120	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.02799613256077782	[566]	[989,797,338]	0	hSpCas9	negative selection	6127562
31598641	31598664	18	-	27260156	CADOES1	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.3685808533691126	[458]	[384,273,315,347]	-6	hSpCas9	negative selection	6184562
31598595	31598618	18	-	27260156	CADOES1	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.5057866402478117	[29]	[97,18,8,31]	8	hSpCas9	negative selection	6184563
31592929	31592952	18	+	27260156	CADOES1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2465211094991824	[473]	[515,530,547,495]	4	hSpCas9	negative selection	6184564
31592917	31592940	18	-	27260156	CADOES1	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.7029290883987647	[624]	[769,1130,803,1085]	9	hSpCas9	negative selection	6248811
31595234	31595257	18	+	27260156	CADOES1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.004057151595826425	[421]	[398,247,454,465]	0	hSpCas9	negative selection	6248812
31595141	31595164	18	+	27260156	CADOES1	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.038469058175864934	[566]	[684,318,556,606]	0	hSpCas9	negative selection	6248813
31598641	31598664	18	-	27260156	EWS502	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.0539441173382666	[458]	[566,342,467,487]	-1	hSpCas9	negative selection	6305813
31598595	31598618	18	-	27260156	EWS502	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.0146292799816528	[29]	[0,1,56,4]	-8	hSpCas9	negative selection	6305814
31592929	31592952	18	+	27260156	EWS502	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.5283675097466523	[473]	[718,567,745,878]	8	hSpCas9	negative selection	6305815
31592917	31592940	18	-	27260156	EWS502	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.46255395075403855	[624]	[832,925,940,957]	7	hSpCas9	negative selection	6370062
31595234	31595257	18	+	27260156	EWS502	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.4314260951363252	[421]	[530,624,711,545]	7	hSpCas9	negative selection	6370063
31595141	31595164	18	+	27260156	EWS502	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.03228127254656327	[566]	[529,644,529,767]	0	hSpCas9	negative selection	6370064
31598641	31598664	18	-	27260156	EW8	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.20907413336393138	[458]	[347,363,252,335]	-4	hSpCas9	negative selection	6427064
31598595	31598618	18	-	27260156	EW8	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.7387294267018585	[29]	[32,9,22,97]	9	hSpCas9	negative selection	6427065
31592929	31592952	18	+	27260156	EW8	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.35158753594326303	[473]	[455,470,382,662]	6	hSpCas9	negative selection	6427066
31592917	31592940	18	-	27260156	EW8	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.4477717259892546	[624]	[751,767,581,684]	7	hSpCas9	negative selection	6491313
31595234	31595257	18	+	27260156	EW8	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.13782301454698792	[421]	[528,401,330,266]	2	hSpCas9	negative selection	6491314
31595141	31595164	18	+	27260156	EW8	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.14444428579754165	[566]	[495,542,477,516]	2	hSpCas9	negative selection	6491315
31598641	31598664	18	-	27260156	CORL105	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.3590102771078897	[458]	[398,544,343,372]	-6	hSpCas9	negative selection	6548315
31598595	31598618	18	-	27260156	CORL105	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.3012466816079429	[29]	[53,8,32,19]	-5	hSpCas9	negative selection	6548316
31592929	31592952	18	+	27260156	CORL105	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.5293188815436679	[473]	[851,745,1000,638]	8	hSpCas9	negative selection	6548317
31592917	31592940	18	-	27260156	CORL105	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.495452674704465	[624]	[976,1065,1087,1000]	8	hSpCas9	negative selection	6612564
31595234	31595257	18	+	27260156	CORL105	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.10596119147379715	[421]	[524,427,594,589]	2	hSpCas9	negative selection	6612565
31595141	31595164	18	+	27260156	CORL105	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.14408911665957908	[566]	[602,596,533,657]	-3	hSpCas9	negative selection	6612566
31598641	31598664	18	-	27260156	HS294T	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.012476915427912173	[458]	[138,227,159,192]	0	hSpCas9	negative selection	6669566
31598595	31598618	18	-	27260156	HS294T	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.08358657912073086	[29]	[16,5,12,12]	1	hSpCas9	negative selection	6669567
31592929	31592952	18	+	27260156	HS294T	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4015245792800619	[473]	[159,290,219,314]	5	hSpCas9	negative selection	6669568
31592917	31592940	18	-	27260156	HS294T	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.6473789700299224	[624]	[522,327,272,375]	8	hSpCas9	negative selection	6733815
31595234	31595257	18	+	27260156	HS294T	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.4570412736319401	[421]	[391,154,180,138]	6	hSpCas9	negative selection	6733816
31595141	31595164	18	+	27260156	HS294T	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.24857779579798567	[566]	[172,122,188,269]	-3	hSpCas9	negative selection	6733817
31598641	31598664	18	-	27260156	HCC44	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.3055886739445624	[458]	[659,325,842,807]	5	hSpCas9	negative selection	6790817
31598595	31598618	18	-	27260156	HCC44	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.573295321833013	[29]	[11,0,22,12]	-9	hSpCas9	negative selection	6790818
31592929	31592952	18	+	27260156	HCC44	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.6639542737324761	[473]	[1070,797,1004,579]	9	hSpCas9	negative selection	6790819
31592917	31592940	18	-	27260156	HCC44	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.423959128911311	[624]	[1246,483,1073,1090]	7	hSpCas9	negative selection	6855066
31595234	31595257	18	+	27260156	HCC44	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.19809742315730117	[421]	[457,241,579,436]	-3	hSpCas9	negative selection	6855067
31595141	31595164	18	+	27260156	HCC44	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.09114013053150138	[566]	[585,694,813,644]	1	hSpCas9	negative selection	6855068
31598641	31598664	18	-	27260156	G402	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.30840759595633255	[458]	[454,697,406,270]	-4	hSpCas9	negative selection	6912068
31598595	31598618	18	-	27260156	G402	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.4915557477288077	[29]	[26,27,77,66]	6	hSpCas9	negative selection	6912069
31592929	31592952	18	+	27260156	G402	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4043611845946542	[473]	[443,710,826,1014]	5	hSpCas9	negative selection	6912070
31592917	31592940	18	-	27260156	G402	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.7591068126636322	[624]	[1435,1246,1112,1375]	8	hSpCas9	negative selection	6976317
31595234	31595257	18	+	27260156	G402	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.3733931462322557	[421]	[493,345,331,425]	-5	hSpCas9	negative selection	6976318
31595141	31595164	18	+	27260156	G402	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.16966504912046726	[566]	[740,615,557,1160]	2	hSpCas9	negative selection	6976319
31598641	31598664	18	-	27260156	L33	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.47308411069540884	[458]	[315,123,186,405]	-8	hSpCas9	negative selection	7033319
31598595	31598618	18	-	27260156	L33	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.2611293683451117	[29]	[19,4,14,43]	-6	hSpCas9	negative selection	7033320
31592929	31592952	18	+	27260156	L33	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.5024647816323101	[473]	[767,298,338,645]	8	hSpCas9	negative selection	7033321
31592917	31592940	18	-	27260156	L33	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.28775107185530086	[624]	[821,289,514,701]	6	hSpCas9	negative selection	7097568
31595234	31595257	18	+	27260156	L33	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-5.3132570616343244e-05	[421]	[364,174,236,518]	0	hSpCas9	negative selection	7097569
31595141	31595164	18	+	27260156	L33	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.009504563365704932	[566]	[561,206,381,607]	0	hSpCas9	negative selection	7097570
31598641	31598664	18	-	27260156	K562	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-1.1540936301502676	[458]	[194,161,339,49]	-8	hSpCas9	negative selection	7154570
31598595	31598618	18	-	27260156	K562	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.5227912489220894	[29]	[20,9,6,0]	-9	hSpCas9	negative selection	7154571
31592929	31592952	18	+	27260156	K562	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.6709130241232686	[473]	[743,441,1162,357]	8	hSpCas9	negative selection	7154572
31592917	31592940	18	-	27260156	K562	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.294203512615619	[624]	[449,454,838,914]	3	hSpCas9	negative selection	7218819
31595234	31595257	18	+	27260156	K562	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.11462245580757689	[421]	[341,766,308,235]	1	hSpCas9	negative selection	7218820
31595141	31595164	18	+	27260156	K562	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.09685775884216011	[566]	[419,583,493,392]	-1	hSpCas9	negative selection	7218821
31598641	31598664	18	-	27260156	HT29	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.14152460969916816	[458]	[727,677,526,546]	2	hSpCas9	negative selection	7275821
31598595	31598618	18	-	27260156	HT29	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.4546695021384255	[29]	[48,28,10,19]	-7	hSpCas9	negative selection	7275822
31592929	31592952	18	+	27260156	HT29	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.24249364764359513	[473]	[571,648,722,756]	5	hSpCas9	negative selection	7275823
31592917	31592940	18	-	27260156	HT29	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.45743746174183236	[624]	[985,1279,968,956]	8	hSpCas9	negative selection	7340070
31595234	31595257	18	+	27260156	HT29	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.36028778314240417	[421]	[838,689,477,640]	7	hSpCas9	negative selection	7340071
31595141	31595164	18	+	27260156	HT29	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.05318984524305212	[566]	[645,776,791,469]	-1	hSpCas9	negative selection	7340072
31598641	31598664	18	-	27260156	MHHES1	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.27401996265024053	[458]	[498,516,334,377]	-5	hSpCas9	negative selection	7397072
31598595	31598618	18	-	27260156	MHHES1	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.33613627913540167	[29]	[11,29,4,102]	6	hSpCas9	negative selection	7397073
31592929	31592952	18	+	27260156	MHHES1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.12033858703115084	[473]	[616,583,398,685]	2	hSpCas9	negative selection	7397074
31592917	31592940	18	-	27260156	MHHES1	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.48100490744131924	[624]	[1274,1064,922,743]	8	hSpCas9	negative selection	7461321
31595234	31595257	18	+	27260156	MHHES1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.02055857480935261	[421]	[420,617,497,404]	0	hSpCas9	negative selection	7461322
31595141	31595164	18	+	27260156	MHHES1	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.21309317091634364	[566]	[612,510,675,424]	-4	hSpCas9	negative selection	7461323
31598641	31598664	18	-	27260156	MEWO	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.14439066157568314	[458]	[564,326,549]	3	hSpCas9	negative selection	7518323
31598595	31598618	18	-	27260156	MEWO	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.033469379873785954	[29]	[37,21,27]	0	hSpCas9	negative selection	7518324
31592929	31592952	18	+	27260156	MEWO	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3643538535277126	[473]	[719,438,582]	7	hSpCas9	negative selection	7518325
31592917	31592940	18	-	27260156	MEWO	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.19544827088978706	[624]	[693,722,595]	4	hSpCas9	negative selection	7582572
31595234	31595257	18	+	27260156	MEWO	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.18738821411751266	[421]	[477,471,403]	4	hSpCas9	negative selection	7582573
31595141	31595164	18	+	27260156	MEWO	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.28994243063342917	[566]	[861,613,510]	6	hSpCas9	negative selection	7582574
31598641	31598664	18	-	27260156	LNCAPCLONEFGC	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.0022142649905028886	[458]	[391,472,455,341]	0	hSpCas9	negative selection	7639574
31598595	31598618	18	-	27260156	LNCAPCLONEFGC	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.3436508136787171	[29]	[30,13,14,24]	-5	hSpCas9	negative selection	7639575
31592929	31592952	18	+	27260156	LNCAPCLONEFGC	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.22257112492133355	[473]	[515,454,659,398]	3	hSpCas9	negative selection	7639576
31592917	31592940	18	-	27260156	LNCAPCLONEFGC	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.43130586186972114	[624]	[873,642,816,732]	6	hSpCas9	negative selection	7703823
31595234	31595257	18	+	27260156	LNCAPCLONEFGC	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.18937802259496608	[421]	[388,400,472,488]	3	hSpCas9	negative selection	7703824
31595141	31595164	18	+	27260156	LNCAPCLONEFGC	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.0028550803470685504	[566]	[508,550,548,451]	0	hSpCas9	negative selection	7703825
31598641	31598664	18	-	27260156	PANC0327	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.10696217360036034	[458]	[371,254,550,351]	-2	hSpCas9	negative selection	7760825
31598595	31598618	18	-	27260156	PANC0327	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.6139776854188335	[29]	[29,14,19,5]	-7	hSpCas9	negative selection	7760826
31592929	31592952	18	+	27260156	PANC0327	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4012547516882279	[473]	[699,525,609,403]	6	hSpCas9	negative selection	7760827
31592917	31592940	18	-	27260156	PANC0327	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.33390770146577936	[624]	[1067,619,464,685]	5	hSpCas9	negative selection	7825074
31595234	31595257	18	+	27260156	PANC0327	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.16825253699687748	[421]	[290,492,195,329]	-3	hSpCas9	negative selection	7825075
31595141	31595164	18	+	27260156	PANC0327	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.12544004129338993	[566]	[256,884,419,567]	1	hSpCas9	negative selection	7825076
31598641	31598664	18	-	27260156	NCIH2009	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.3321670056088199	[458]	[576,548,413]	-4	hSpCas9	negative selection	7882076
31598595	31598618	18	-	27260156	NCIH2009	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.22740403361404793	[29]	[27,24,52]	-3	hSpCas9	negative selection	7882077
31592929	31592952	18	+	27260156	NCIH2009	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.568873091698692	[473]	[1279,995,727]	7	hSpCas9	negative selection	7882078
31592917	31592940	18	-	27260156	NCIH2009	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.40542366787727374	[624]	[1204,1007,1266]	5	hSpCas9	negative selection	7946325
31595234	31595257	18	+	27260156	NCIH2009	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.17948709191359558	[421]	[869,776,392]	2	hSpCas9	negative selection	7946326
31595141	31595164	18	+	27260156	NCIH2009	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.025203127629347122	[566]	[1068,862,535]	0	hSpCas9	negative selection	7946327
31598641	31598664	18	-	27260156	NCIH1373	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.44579190925101436	[458]	[251,408,316,135]	-4	hSpCas9	negative selection	8003327
31598595	31598618	18	-	27260156	NCIH1373	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.7462054619936436	[29]	[18,5,22,8]	-6	hSpCas9	negative selection	8003328
31592929	31592952	18	+	27260156	NCIH1373	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.07083645167590424	[473]	[753,405,661,116]	0	hSpCas9	negative selection	8003329
31592917	31592940	18	-	27260156	NCIH1373	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.6393896670757779	[624]	[1281,1271,810,263]	6	hSpCas9	negative selection	8067576
31595234	31595257	18	+	27260156	NCIH1373	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.40703199456070926	[421]	[580,377,462,298]	4	hSpCas9	negative selection	8067577
31595141	31595164	18	+	27260156	NCIH1373	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.3399356497720055	[566]	[576,475,1499,166]	3	hSpCas9	negative selection	8067578
31598641	31598664	18	-	27260156	PATU8902	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.12849949030706967	[458]	[937,611,406,932]	1	hSpCas9	negative selection	8124578
31598595	31598618	18	-	27260156	PATU8902	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.36327521593461976	[29]	[3,12,158,5]	4	hSpCas9	negative selection	8124579
31592929	31592952	18	+	27260156	PATU8902	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3677578606098152	[473]	[1226,944,344,1031]	4	hSpCas9	negative selection	8124580
31592917	31592940	18	-	27260156	PATU8902	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	1.0754285947620084	[624]	[1491,2158,1458,2380]	9	hSpCas9	negative selection	8188827
31595234	31595257	18	+	27260156	PATU8902	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.11061901351268895	[421]	[812,543,463,769]	1	hSpCas9	negative selection	8188828
31595141	31595164	18	+	27260156	PATU8902	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.18417887161266144	[566]	[959,696,487,1628]	1	hSpCas9	negative selection	8188829
31598641	31598664	18	-	27260156	PANC1	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.20216664310199234	[458]	[509,749,277,344]	3	hSpCas9	negative selection	8245829
31598595	31598618	18	-	27260156	PANC1	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.27812944547720564	[29]	[3,58,3,24]	-4	hSpCas9	negative selection	8245830
31592929	31592952	18	+	27260156	PANC1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.47386520356574224	[473]	[612,644,545,477]	7	hSpCas9	negative selection	8245831
31592917	31592940	18	-	27260156	PANC1	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.5897669971799533	[624]	[620,1091,969,628]	8	hSpCas9	negative selection	8310078
31595234	31595257	18	+	27260156	PANC1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.6164406335418753	[421]	[670,708,474,410]	8	hSpCas9	negative selection	8310079
31595141	31595164	18	+	27260156	PANC1	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.19302518121387652	[566]	[480,673,583,511]	3	hSpCas9	negative selection	8310080
31598641	31598664	18	-	27260156	PANC0813	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.3303078831149437	[458]	[305,506,523,369]	-5	hSpCas9	negative selection	8367080
31598595	31598618	18	-	27260156	PANC0813	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.5074920510849767	[29]	[5,26,4,10]	-9	hSpCas9	negative selection	8367081
31592929	31592952	18	+	27260156	PANC0813	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.10243465677924687	[473]	[705,664,461,567]	1	hSpCas9	negative selection	8367082
31592917	31592940	18	-	27260156	PANC0813	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.029259150925003308	[624]	[731,797,701,760]	0	hSpCas9	negative selection	8431329
31595234	31595257	18	+	27260156	PANC0813	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.37690610888323683	[421]	[326,451,581,172]	-5	hSpCas9	negative selection	8431330
31595141	31595164	18	+	27260156	PANC0813	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.6686915556274355	[566]	[555,429,329,373]	-7	hSpCas9	negative selection	8431331
31598641	31598664	18	-	27260156	RDES	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.2664248951863613	[458]	[271,473,605,428]	-4	hSpCas9	negative selection	8488331
31598595	31598618	18	-	27260156	RDES	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.1422933926921428	[29]	[27,33,48,10]	-2	hSpCas9	negative selection	8488332
31592929	31592952	18	+	27260156	RDES	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.5573641673861067	[473]	[599,703,1042,918]	8	hSpCas9	negative selection	8488333
31592917	31592940	18	-	27260156	RDES	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.503980404107911	[624]	[848,963,1096,1209]	7	hSpCas9	negative selection	8552580
31595234	31595257	18	+	27260156	RDES	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.005123630953440345	[421]	[410,494,499,552]	0	hSpCas9	negative selection	8552581
31595141	31595164	18	+	27260156	RDES	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.2322252640869312	[566]	[430,533,608,679]	-4	hSpCas9	negative selection	8552582
31598641	31598664	18	-	27260156	PC3	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.07062954005678745	[458]	[389,477,628,461]	1	hSpCas9	negative selection	8609582
31598595	31598618	18	-	27260156	PC3	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.5739694157027726	[29]	[20,86,12,48]	9	hSpCas9	negative selection	8609583
31592929	31592952	18	+	27260156	PC3	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3165664240416477	[473]	[428,641,887,507]	6	hSpCas9	negative selection	8609584
31592917	31592940	18	-	27260156	PC3	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.3509332142990839	[624]	[609,653,1474,696]	7	hSpCas9	negative selection	8673831
31595234	31595257	18	+	27260156	PC3	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.17948253924431362	[421]	[394,257,822,557]	4	hSpCas9	negative selection	8673832
31595141	31595164	18	+	27260156	PC3	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.15950883931635906	[566]	[301,502,942,487]	-4	hSpCas9	negative selection	8673833
31598641	31598664	18	-	27260156	PATU8988T	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.20793978495609494	[458]	[554,356,610,509]	3	hSpCas9	negative selection	8730833
31598595	31598618	18	-	27260156	PATU8988T	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-1.4156082958831218	[29]	[0,1,2,38]	-9	hSpCas9	negative selection	8730834
31592929	31592952	18	+	27260156	PATU8988T	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3411374397092563	[473]	[518,601,573,631]	6	hSpCas9	negative selection	8730835
31592917	31592940	18	-	27260156	PATU8988T	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.3601556492337569	[624]	[896,798,631,776]	6	hSpCas9	negative selection	8795082
31595234	31595257	18	+	27260156	PATU8988T	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.016959187546071508	[421]	[488,424,273,429]	0	hSpCas9	negative selection	8795083
31595141	31595164	18	+	27260156	PATU8988T	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.20705694104388433	[566]	[687,657,350,856]	3	hSpCas9	negative selection	8795084
31598641	31598664	18	-	27260156	T47D	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.10746263929644484	[458]	[559,612,596,528]	2	hSpCas9	negative selection	8852084
31598595	31598618	18	-	27260156	T47D	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.2668235292420458	[29]	[34,39,54,37]	5	hSpCas9	negative selection	8852085
31592929	31592952	18	+	27260156	T47D	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4963214470577111	[473]	[818,783,671,843]	9	hSpCas9	negative selection	8852086
31592917	31592940	18	-	27260156	T47D	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.5109041549628457	[624]	[1003,1031,983,1133]	9	hSpCas9	negative selection	8916333
31595234	31595257	18	+	27260156	T47D	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.08139493376611455	[421]	[611,458,587,422]	1	hSpCas9	negative selection	8916334
31595141	31595164	18	+	27260156	T47D	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.26514779169173813	[566]	[593,547,454,604]	-5	hSpCas9	negative selection	8916335
31598641	31598664	18	-	27260156	SU8686	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	2.6657275346980702e-05	[458]	[469,449,417,480]	0	hSpCas9	negative selection	8973335
31598595	31598618	18	-	27260156	SU8686	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.4970968467713619	[29]	[6,28,20,28]	-7	hSpCas9	negative selection	8973336
31592929	31592952	18	+	27260156	SU8686	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.506581998339832	[473]	[562,736,759,599]	8	hSpCas9	negative selection	8973337
31592917	31592940	18	-	27260156	SU8686	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.42740295789060084	[624]	[768,770,800,1032]	7	hSpCas9	negative selection	9037584
31595234	31595257	18	+	27260156	SU8686	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.1453280015917246	[421]	[454,534,387,457]	2	hSpCas9	negative selection	9037585
31595141	31595164	18	+	27260156	SU8686	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.12202189488283005	[566]	[496,597,594,796]	2	hSpCas9	negative selection	9037586
31598641	31598664	18	-	27260156	SKES1	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.10501878580822577	[458]	[666,507,430,396]	2	hSpCas9	negative selection	9094586
31598595	31598618	18	-	27260156	SKES1	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.19614760043683654	[29]	[59,25,23,29]	4	hSpCas9	negative selection	9094587
31592929	31592952	18	+	27260156	SKES1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2696284378490987	[473]	[703,526,534,526]	6	hSpCas9	negative selection	9094588
31592917	31592940	18	-	27260156	SKES1	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.49670560785991597	[624]	[914,1072,897,675]	8	hSpCas9	negative selection	9158835
31595234	31595257	18	+	27260156	SKES1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.07915182349102254	[421]	[374,626,343,441]	1	hSpCas9	negative selection	9158836
31595141	31595164	18	+	27260156	SKES1	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.08774929278105714	[566]	[738,474,565,619]	2	hSpCas9	negative selection	9158837
31598641	31598664	18	-	27260156	TOV112D	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.15805247758574192	[458]	[733,469,488,369]	3	hSpCas9	negative selection	9215837
31598595	31598618	18	-	27260156	TOV112D	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.14081551389279046	[29]	[33,20,57,16]	2	hSpCas9	negative selection	9215838
31592929	31592952	18	+	27260156	TOV112D	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3945105977867401	[473]	[516,566,652,731]	7	hSpCas9	negative selection	9215839
31592917	31592940	18	-	27260156	TOV112D	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.49382811134527843	[624]	[1136,1483,581,501]	8	hSpCas9	negative selection	9280086
31595234	31595257	18	+	27260156	TOV112D	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.07421234462055532	[421]	[560,450,332,288]	-1	hSpCas9	negative selection	9280087
31595141	31595164	18	+	27260156	TOV112D	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.05663622082372216	[566]	[573,661,465,512]	-1	hSpCas9	negative selection	9280088
31598641	31598664	18	-	27260156	TC71	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	-0.0062123372521950965	[458]	[494,464,566,425]	0	hSpCas9	negative selection	9337088
31598595	31598618	18	-	27260156	TC71	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	-0.5911433461962843	[29]	[44,16,6,15]	-9	hSpCas9	negative selection	9337089
31592929	31592952	18	+	27260156	TC71	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.29015001312438504	[473]	[526,661,589,714]	7	hSpCas9	negative selection	9337090
31592917	31592940	18	-	27260156	TC71	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.33179578523375347	[624]	[871,850,769,883]	7	hSpCas9	negative selection	9401337
31595234	31595257	18	+	27260156	TC71	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.22563340236892865	[421]	[619,529,503,455]	5	hSpCas9	negative selection	9401338
31595141	31595164	18	+	27260156	TC71	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	0.007378408631711797	[566]	[603,584,569,690]	0	hSpCas9	negative selection	9401339
31598641	31598664	18	-	27260156	TC32	viability	ATTGGTGACGACAGCCGTGGTGG	TTR	ENSG00000118271	0.01602129690232933	[458]	[479,242,414,657]	0	hSpCas9	negative selection	9458339
31598595	31598618	18	-	27260156	TC32	viability	GCGGCAATGGTGTAGCGGCGGGG	TTR	ENSG00000118271	0.8225725576571108	[29]	[3,107,48,15]	9	hSpCas9	negative selection	9458340
31592929	31592952	18	+	27260156	TC32	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.2217116426121008	[473]	[570,313,765,509]	4	hSpCas9	negative selection	9458341
31592917	31592940	18	-	27260156	TC32	viability	TCTAGAACTTTGACCATCAGAGG	TTR	ENSG00000118271	0.671816175581839	[624]	[941,813,1030,958]	9	hSpCas9	negative selection	9522588
31595234	31595257	18	+	27260156	TC32	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.078165494124126	[421]	[430,382,445,402]	1	hSpCas9	negative selection	9522589
31595141	31595164	18	+	27260156	TC32	viability	GCTGCATGGGCTCACAACTGAGG	TTR	ENSG00000118271	-0.08705069019437	[566]	[580,236,802,499]	-1	hSpCas9	negative selection	9522590
31593020	31593043	18	-	27869803	HPAFII	viability after 27 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.025266758610430113	[248]	[198,69,NaN]	0	hSpCas9	negative selection	9564375
31595144	31595167	18	+	27869803	HPAFII	viability after 27 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.06320721419506925	[355]	[140,240,NaN]	0	hSpCas9	negative selection	9564376
31595235	31595258	18	-	27869803	HPAFII	viability after 27 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.62638089322211	[233]	[232,153,NaN]	5	hSpCas9	negative selection	9564377
31598594	31598617	18	-	27869803	HPAFII	viability after 27 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	-0.008456486892331583	[374]	[117,260,NaN]	0	hSpCas9	negative selection	9564378
31598596	31598619	18	-	27869803	HPAFII	viability after 27 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.21405095499690785	[139]	[87,42,NaN]	-1	hSpCas9	negative selection	9564379
31598648	31598671	18	+	27869803	HPAFII	viability after 27 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.16671857080906394	[124]	[63,53,NaN]	-1	hSpCas9	negative selection	9564380
31593020	31593043	18	-	27869803	HPAFII	viability after 15 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.38968706741315545	[248]	[476,271,NaN]	4	hSpCas9	negative selection	9646824
31595144	31595167	18	+	27869803	HPAFII	viability after 15 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.09901994306020112	[355]	[439,390,NaN]	1	hSpCas9	negative selection	9646825
31595235	31595258	18	-	27869803	HPAFII	viability after 15 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.45933858711749587	[233]	[576,201,NaN]	5	hSpCas9	negative selection	9646826
31598594	31598617	18	-	27869803	HPAFII	viability after 15 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	-0.09709162042241948	[374]	[480,311,NaN]	-1	hSpCas9	negative selection	9646827
31598596	31598619	18	-	27869803	HPAFII	viability after 15 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.6017106075812879	[139]	[178,258,NaN]	6	hSpCas9	negative selection	9646828
31598648	31598671	18	+	27869803	HPAFII	viability after 15 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.6160736375700651	[124]	[253,175,NaN]	7	hSpCas9	negative selection	9646829
31593020	31593043	18	-	27869803	ASPC1	viability after 36 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	-0.0674540761867371	[533]	[171,264,110]	0	hSpCas9	negative selection	9729273
31595144	31595167	18	+	27869803	ASPC1	viability after 36 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	1.0058261882521415	[757]	[590,699,349]	8	hSpCas9	negative selection	9729274
31595235	31595258	18	-	27869803	ASPC1	viability after 36 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.10334513533965572	[650]	[251,320,174]	1	hSpCas9	negative selection	9729275
31598594	31598617	18	-	27869803	ASPC1	viability after 36 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.02907938570489854	[1288]	[752,554,171]	0	hSpCas9	negative selection	9729276
31598596	31598619	18	-	27869803	ASPC1	viability after 36 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.185503478000548	[283]	[220,35,32]	-2	hSpCas9	negative selection	9729277
31598648	31598671	18	+	27869803	ASPC1	viability after 36 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	-0.46224380595401776	[449]	[221,132,21]	-5	hSpCas9	negative selection	9729278
31593020	31593043	18	-	27869803	PATU8988S	viability after 35 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.14152804941819164	[509]	[258,193,NaN]	1	hSpCas9	negative selection	9811722
31595144	31595167	18	+	27869803	PATU8988S	viability after 35 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.7044597809089304	[571]	[331,418,NaN]	7	hSpCas9	negative selection	9811723
31595235	31595258	18	-	27869803	PATU8988S	viability after 35 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.5143540924947224	[527]	[190,416,NaN]	6	hSpCas9	negative selection	9811724
31598594	31598617	18	-	27869803	PATU8988S	viability after 35 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.2008605805743804	[933]	[371,492,NaN]	2	hSpCas9	negative selection	9811725
31598596	31598619	18	-	27869803	PATU8988S	viability after 35 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.5942349347094036	[341]	[182,232,NaN]	6	hSpCas9	negative selection	9811726
31598648	31598671	18	+	27869803	PATU8988S	viability after 35 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.7609472596764644	[350]	[264,213,NaN]	7	hSpCas9	negative selection	9811727
31593020	31593043	18	-	27869803	PATU8988S	viability after 31 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.14875641380143462	[509]	[257,183,NaN]	1	hSpCas9	negative selection	9894171
31595144	31595167	18	+	27869803	PATU8988S	viability after 31 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.8435683492278581	[571]	[253,606,NaN]	8	hSpCas9	negative selection	9894172
31595235	31595258	18	-	27869803	PATU8988S	viability after 31 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.45204350917014374	[527]	[137,478,NaN]	5	hSpCas9	negative selection	9894173
31598594	31598617	18	-	27869803	PATU8988S	viability after 31 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.42200578357396956	[933]	[366,666,NaN]	5	hSpCas9	negative selection	9894174
31598596	31598619	18	-	27869803	PATU8988S	viability after 31 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.268578332027293	[341]	[136,198,NaN]	3	hSpCas9	negative selection	9894175
31598648	31598671	18	+	27869803	PATU8988S	viability after 31 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.7610008663546449	[350]	[157,337,NaN]	8	hSpCas9	negative selection	9894176
31593020	31593043	18	-	27869803	HPAFII	viability after 35 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.052328471312761096	[248]	[141,117,NaN]	0	hSpCas9	negative selection	9976620
31595144	31595167	18	+	27869803	HPAFII	viability after 35 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.6150035376555296	[355]	[204,355,NaN]	4	hSpCas9	negative selection	9976621
31595235	31595258	18	-	27869803	HPAFII	viability after 35 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.5353006757942835	[233]	[237,96,NaN]	3	hSpCas9	negative selection	9976622
31598594	31598617	18	-	27869803	HPAFII	viability after 35 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	0.43432350902308803	[374]	[137,389,NaN]	3	hSpCas9	negative selection	9976623
31598596	31598619	18	-	27869803	HPAFII	viability after 35 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	-0.45676853443521837	[139]	[37,66,NaN]	-3	hSpCas9	negative selection	9976624
31598648	31598671	18	+	27869803	HPAFII	viability after 35 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.25912063426382037	[124]	[126,17,NaN]	1	hSpCas9	negative selection	9976625
31593020	31593043	18	-	27869803	HPAFII	viability after 31 days	TTCTTTGGCAACTTACCCAGAGG	TTR	ENSG00000118271	0.2448036687567075	[248]	[200,126,NaN]	1	hSpCas9	negative selection	10059069
31595144	31595167	18	+	27869803	HPAFII	viability after 31 days	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.5935836010154383	[355]	[155,459,NaN]	4	hSpCas9	negative selection	10059070
31595235	31595258	18	-	27869803	HPAFII	viability after 31 days	ACCTCTGCATGCTCATGGAATGG	TTR	ENSG00000118271	0.6726319095305151	[233]	[238,176,NaN]	5	hSpCas9	negative selection	10059071
31598594	31598617	18	-	27869803	HPAFII	viability after 31 days	CGGCAATGGTGTAGCGGCGGGGG	TTR	ENSG00000118271	-0.03002489936901065	[374]	[85,336,NaN]	0	hSpCas9	negative selection	10059072
31598596	31598619	18	-	27869803	HPAFII	viability after 31 days	GGCGGCAATGGTGTAGCGGCGGG	TTR	ENSG00000118271	0.5453604801078434	[139]	[95,134,NaN]	4	hSpCas9	negative selection	10059073
31598648	31598671	18	+	27869803	HPAFII	viability after 31 days	GGCTGTCGTCACCAATCCCAAGG	TTR	ENSG00000118271	0.7816730120258931	[124]	[200,32,NaN]	6	hSpCas9	negative selection	10059074
31595144	31595167	18	+	28162770	P31FUJ	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.24395107935088073	[142]	[198]	2	hSpCas9	negative selection	10259117
31595157	31595180	18	+	28162770	P31FUJ	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.4289174952908154	[243]	[385]	5	hSpCas9	negative selection	10259118
31591926	31591949	18	-	28162770	P31FUJ	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.8292074578610462	[443]	[926]	8	hSpCas9	negative selection	10259119
31592987	31593010	18	+	28162770	P31FUJ	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.28459701249414304	[152]	[218]	3	hSpCas9	negative selection	10259120
31592946	31592969	18	-	28162770	P31FUJ	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.6324483834723839	[156]	[285]	7	hSpCas9	negative selection	10259121
31595128	31595151	18	+	28162770	P31FUJ	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.16312647191676055	[132]	[174]	1	hSpCas9	negative selection	10259122
31592929	31592952	18	+	28162770	P31FUJ	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.43637330020986276	[121]	[193]	5	hSpCas9	negative selection	10259123
31595234	31595257	18	+	28162770	P31FUJ	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.011471273310753594	[644]	[763]	0	hSpCas9	negative selection	10259124
31592956	31592979	18	-	28162770	P31FUJ	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.2653170363590203	[193]	[273]	3	hSpCas9	negative selection	10259125
31592972	31592995	18	-	28162770	P31FUJ	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.4672674580514018	[39]	[33]	-4	hSpCas9	negative selection	10259126
31595144	31595167	18	+	28162770	TF1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10428483
31595157	31595180	18	+	28162770	TF1	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	NaN	[NaN]	[420]	1	hSpCas9	negative selection	10428484
31591926	31591949	18	-	28162770	TF1	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	NaN	[NaN]	[642]	1	hSpCas9	negative selection	10428485
31592987	31593010	18	+	28162770	TF1	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10428486
31592946	31592969	18	-	28162770	TF1	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	NaN	[NaN]	[309]	1	hSpCas9	negative selection	10428487
31595128	31595151	18	+	28162770	TF1	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10428488
31592929	31592952	18	+	28162770	TF1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10428489
31595234	31595257	18	+	28162770	TF1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	NaN	[NaN]	[541]	1	hSpCas9	negative selection	10428490
31592956	31592979	18	-	28162770	TF1	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	NaN	[NaN]	[337]	1	hSpCas9	negative selection	10428491
31592972	31592995	18	-	28162770	TF1	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10428492
31595144	31595167	18	+	28162770	SKM1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.6633039520029473	[42]	[47]	-5	hSpCas9	negative selection	10597849
31595157	31595180	18	+	28162770	SKM1	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.7629608026991508	[46]	[140]	7	hSpCas9	negative selection	10597850
31591926	31591949	18	-	28162770	SKM1	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.17264506748378783	[134]	[268]	1	hSpCas9	negative selection	10597851
31592987	31593010	18	+	28162770	SKM1	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-0.21431912080076565	[41]	[63]	-2	hSpCas9	negative selection	10597852
31592946	31592969	18	-	28162770	SKM1	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.5453693676265238	[49]	[128]	5	hSpCas9	negative selection	10597853
31595128	31595151	18	+	28162770	SKM1	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.5868038475453237	[57]	[153]	5	hSpCas9	negative selection	10597854
31592929	31592952	18	+	28162770	SKM1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.39750386949409555	[37]	[50]	-3	hSpCas9	negative selection	10597855
31595234	31595257	18	+	28162770	SKM1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.42771835453090756	[126]	[301]	4	hSpCas9	negative selection	10597856
31592956	31592979	18	-	28162770	SKM1	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	1.8092544549730858	[45]	[284]	9	hSpCas9	negative selection	10597857
31592972	31592995	18	-	28162770	SKM1	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.7288922936305238	[14]	[15]	-5	hSpCas9	negative selection	10597858
31595144	31595167	18	+	28162770	SKM1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.6633039520029473	[42]	[47]	-5	hSpCas9	negative selection	10767215
31595157	31595180	18	+	28162770	SKM1	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.7629608026991508	[46]	[140]	7	hSpCas9	negative selection	10767216
31591926	31591949	18	-	28162770	SKM1	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.17264506748378783	[134]	[268]	1	hSpCas9	negative selection	10767217
31592987	31593010	18	+	28162770	SKM1	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-0.21431912080076565	[41]	[63]	-2	hSpCas9	negative selection	10767218
31592946	31592969	18	-	28162770	SKM1	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.5453693676265238	[49]	[128]	5	hSpCas9	negative selection	10767219
31595128	31595151	18	+	28162770	SKM1	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.5868038475453237	[57]	[153]	5	hSpCas9	negative selection	10767220
31592929	31592952	18	+	28162770	SKM1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.39750386949409555	[37]	[50]	-3	hSpCas9	negative selection	10767221
31595234	31595257	18	+	28162770	SKM1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.42771835453090756	[126]	[301]	4	hSpCas9	negative selection	10767222
31592956	31592979	18	-	28162770	SKM1	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	1.8092544549730858	[45]	[284]	9	hSpCas9	negative selection	10767223
31592972	31592995	18	-	28162770	SKM1	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.7288922936305238	[14]	[15]	-5	hSpCas9	negative selection	10767224
31595144	31595167	18	+	28162770	PL21	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.4302593978503789	[132]	[77]	4	hSpCas9	negative selection	10936581
31595157	31595180	18	+	28162770	PL21	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.6437462659649348	[149]	[101]	5	hSpCas9	negative selection	10936582
31591926	31591949	18	-	28162770	PL21	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.32474717171549394	[520]	[283]	3	hSpCas9	negative selection	10936583
31592987	31593010	18	+	28162770	PL21	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-1.626711483194081	[148]	[20]	-8	hSpCas9	negative selection	10936584
31592946	31592969	18	-	28162770	PL21	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.2605122324688018	[233]	[121]	2	hSpCas9	negative selection	10936585
31595128	31595151	18	+	28162770	PL21	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.23116651010994474	[183]	[93]	2	hSpCas9	negative selection	10936586
31592929	31592952	18	+	28162770	PL21	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	1.3576808914758003	[77]	[86]	9	hSpCas9	negative selection	10936587
31595234	31595257	18	+	28162770	PL21	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.2817899035057376	[394]	[208]	2	hSpCas9	negative selection	10936588
31592956	31592979	18	-	28162770	PL21	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.12485148718508292	[176]	[83]	1	hSpCas9	negative selection	10936589
31592972	31592995	18	-	28162770	PL21	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.5103537683156949	[35]	[10]	-4	hSpCas9	negative selection	10936590
31595144	31595167	18	+	28162770	P31FUJ	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.24395107935088073	[142]	[198]	2	hSpCas9	negative selection	11105947
31595157	31595180	18	+	28162770	P31FUJ	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.4289174952908154	[243]	[385]	5	hSpCas9	negative selection	11105948
31591926	31591949	18	-	28162770	P31FUJ	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.8292074578610462	[443]	[926]	8	hSpCas9	negative selection	11105949
31592987	31593010	18	+	28162770	P31FUJ	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.28459701249414304	[152]	[218]	3	hSpCas9	negative selection	11105950
31592946	31592969	18	-	28162770	P31FUJ	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.6324483834723839	[156]	[285]	7	hSpCas9	negative selection	11105951
31595128	31595151	18	+	28162770	P31FUJ	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.16312647191676055	[132]	[174]	1	hSpCas9	negative selection	11105952
31592929	31592952	18	+	28162770	P31FUJ	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.43637330020986276	[121]	[193]	5	hSpCas9	negative selection	11105953
31595234	31595257	18	+	28162770	P31FUJ	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.011471273310753594	[644]	[763]	0	hSpCas9	negative selection	11105954
31592956	31592979	18	-	28162770	P31FUJ	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.2653170363590203	[193]	[273]	3	hSpCas9	negative selection	11105955
31592972	31592995	18	-	28162770	P31FUJ	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.4672674580514018	[39]	[33]	-4	hSpCas9	negative selection	11105956
31595144	31595167	18	+	28162770	OCIAML5	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.7188000400005328	[30]	[33]	-5	hSpCas9	negative selection	11275313
31595157	31595180	18	+	28162770	OCIAML5	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.7099955277470805	[126]	[374]	6	hSpCas9	negative selection	11275314
31591926	31591949	18	-	28162770	OCIAML5	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	-0.19445876831107478	[283]	[447]	-1	hSpCas9	negative selection	11275315
31592987	31593010	18	+	28162770	OCIAML5	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-2.1739946657513594	[109]	[43]	-8	hSpCas9	negative selection	11275316
31592946	31592969	18	-	28162770	OCIAML5	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.203074983328464	[76]	[319]	8	hSpCas9	negative selection	11275317
31595128	31595151	18	+	28162770	OCIAML5	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	-0.34642652280424635	[80]	[114]	-2	hSpCas9	negative selection	11275318
31592929	31592952	18	+	28162770	OCIAML5	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	1.1021297395228782	[87]	[340]	8	hSpCas9	negative selection	11275319
31595234	31595257	18	+	28162770	OCIAML5	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.5485541556459728	[263]	[696]	5	hSpCas9	negative selection	11275320
31592956	31592979	18	-	28162770	OCIAML5	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.50003967268839	[122]	[313]	4	hSpCas9	negative selection	11275321
31592972	31592995	18	-	28162770	OCIAML5	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.9881529850992337	[30]	[110]	8	hSpCas9	negative selection	11275322
31595144	31595167	18	+	28162770	EOL1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.4323424117692308	[255]	[181]	4	hSpCas9	negative selection	11444679
31595157	31595180	18	+	28162770	EOL1	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.27493231250712497	[250]	[159]	2	hSpCas9	negative selection	11444680
31591926	31591949	18	-	28162770	EOL1	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.936871050020665	[815]	[822]	7	hSpCas9	negative selection	11444681
31592987	31593010	18	+	28162770	EOL1	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	-0.5526585487947389	[244]	[87]	-4	hSpCas9	negative selection	11444682
31592946	31592969	18	-	28162770	EOL1	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.2497886004987324	[347]	[217]	2	hSpCas9	negative selection	11444683
31595128	31595151	18	+	28162770	EOL1	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	-0.052442250382965044	[310]	[157]	0	hSpCas9	negative selection	11444684
31592929	31592952	18	+	28162770	EOL1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3916737819978324	[135]	[93]	3	hSpCas9	negative selection	11444685
31595234	31595257	18	+	28162770	EOL1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	1.4976885638308461	[530]	[789]	9	hSpCas9	negative selection	11444686
31592956	31592979	18	-	28162770	EOL1	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	1.0330722283487037	[191]	[206]	8	hSpCas9	negative selection	11444687
31592972	31592995	18	-	28162770	EOL1	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.6318455769538507	[49]	[16]	-4	hSpCas9	negative selection	11444688
31595144	31595167	18	+	28162770	MOLM13	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.3585907390537671	[232]	[215]	2	hSpCas9	negative selection	11614045
31595157	31595180	18	+	28162770	MOLM13	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.4830491887155845	[283]	[286]	3	hSpCas9	negative selection	11614046
31591926	31591949	18	-	28162770	MOLM13	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.5384700609901918	[717]	[753]	4	hSpCas9	negative selection	11614047
31592987	31593010	18	+	28162770	MOLM13	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.676332244196803	[192]	[222]	5	hSpCas9	negative selection	11614048
31592946	31592969	18	-	28162770	MOLM13	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.3659174084433013	[380]	[354]	2	hSpCas9	negative selection	11614049
31595128	31595151	18	+	28162770	MOLM13	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.1300197427881949	[272]	[215]	0	hSpCas9	negative selection	11614050
31592929	31592952	18	+	28162770	MOLM13	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.48548344155931705	[162]	[164]	3	hSpCas9	negative selection	11614051
31595234	31595257	18	+	28162770	MOLM13	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.888010269645749	[708]	[276]	-5	hSpCas9	negative selection	11614052
31592956	31592979	18	-	28162770	MOLM13	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.7809271673210271	[292]	[363]	6	hSpCas9	negative selection	11614053
31592972	31592995	18	-	28162770	MOLM13	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	1.0634991264652438	[44]	[67]	7	hSpCas9	negative selection	11614054
31595144	31595167	18	+	28162770	HEL	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.32723700627242747	[167]	[134]	2	hSpCas9	negative selection	11783411
31595157	31595180	18	+	28162770	HEL	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	-1.003862734513185	[262]	[83]	-6	hSpCas9	negative selection	11783412
31591926	31591949	18	-	28162770	HEL	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	1.0577763312792008	[533]	[711]	8	hSpCas9	negative selection	11783413
31592987	31593010	18	+	28162770	HEL	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.5908999004807389	[169]	[163]	5	hSpCas9	negative selection	11783414
31592946	31592969	18	-	28162770	HEL	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.0053089113850655	[286]	[368]	8	hSpCas9	negative selection	11783415
31595128	31595151	18	+	28162770	HEL	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.5693656456701377	[241]	[229]	5	hSpCas9	negative selection	11783416
31592929	31592952	18	+	28162770	HEL	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	1.5161583354352142	[124]	[228]	9	hSpCas9	negative selection	11783417
31595234	31595257	18	+	28162770	HEL	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.09179326950563693	[481]	[328]	0	hSpCas9	negative selection	11783418
31592956	31592979	18	-	28162770	HEL	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.027823109177573024	[218]	[142]	0	hSpCas9	negative selection	11783419
31592972	31592995	18	-	28162770	HEL	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-0.7978337593856244	[75]	[27]	-5	hSpCas9	negative selection	11783420
31595144	31595167	18	+	28162770	MV411	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.4306343543298623	[119]	[74]	-3	hSpCas9	negative selection	11952777
31595157	31595180	18	+	28162770	MV411	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	1.0496307677246006	[159]	[278]	8	hSpCas9	negative selection	11952778
31591926	31591949	18	-	28162770	MV411	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.5353516134050837	[411]	[502]	5	hSpCas9	negative selection	11952779
31592987	31593010	18	+	28162770	MV411	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.8485197168672085	[88]	[134]	7	hSpCas9	negative selection	11952780
31592946	31592969	18	-	28162770	MV411	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.6732014566546776	[200]	[539]	9	hSpCas9	negative selection	11952781
31595128	31595151	18	+	28162770	MV411	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.21239060368357449	[124]	[121]	1	hSpCas9	negative selection	11952782
31592929	31592952	18	+	28162770	MV411	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4953650642263608	[127]	[151]	4	hSpCas9	negative selection	11952783
31595234	31595257	18	+	28162770	MV411	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.18528107472020605	[331]	[317]	1	hSpCas9	negative selection	11952784
31592956	31592979	18	-	28162770	MV411	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.6194063281697331	[152]	[197]	5	hSpCas9	negative selection	11952785
31592972	31592995	18	-	28162770	MV411	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.2869659149694126	[35]	[36]	2	hSpCas9	negative selection	11952786
31595144	31595167	18	+	28162770	MONOMAC1	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	-0.34246728658111747	[72]	[65]	-3	hSpCas9	negative selection	12122143
31595157	31595180	18	+	28162770	MONOMAC1	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.036162329233477064	[113]	[133]	0	hSpCas9	negative selection	12122144
31591926	31591949	18	-	28162770	MONOMAC1	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	-0.20625537708893238	[313]	[311]	-2	hSpCas9	negative selection	12122145
31592987	31593010	18	+	28162770	MONOMAC1	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.5175609340781979	[77]	[127]	5	hSpCas9	negative selection	12122146
31592946	31592969	18	-	28162770	MONOMAC1	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.1780025842873707	[127]	[331]	8	hSpCas9	negative selection	12122147
31595128	31595151	18	+	28162770	MONOMAC1	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	1.0816791810065098	[121]	[295]	8	hSpCas9	negative selection	12122148
31592929	31592952	18	+	28162770	MONOMAC1	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	-0.484613437156139	[82]	[67]	-4	hSpCas9	negative selection	12122149
31595234	31595257	18	+	28162770	MONOMAC1	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	0.11039167813269346	[239]	[296]	1	hSpCas9	negative selection	12122150
31592956	31592979	18	-	28162770	MONOMAC1	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.354867365082307	[102]	[150]	3	hSpCas9	negative selection	12122151
31592972	31592995	18	-	28162770	MONOMAC1	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	-2.241430966418007	[32]	[7]	-9	hSpCas9	negative selection	12122152
31595144	31595167	18	+	28162770	OCIAML2	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	0.3790359016734073	[23]	[172]	3	hSpCas9	negative selection	12291509
31595157	31595180	18	+	28162770	OCIAML2	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	0.14604153520633306	[44]	[275]	1	hSpCas9	negative selection	12291510
31591926	31591949	18	-	28162770	OCIAML2	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.23810921611741787	[79]	[522]	2	hSpCas9	negative selection	12291511
31592987	31593010	18	+	28162770	OCIAML2	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.4487517145495543	[22]	[173]	4	hSpCas9	negative selection	12291512
31592946	31592969	18	-	28162770	OCIAML2	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	1.4947564196765017	[28]	[452]	9	hSpCas9	negative selection	12291513
31595128	31595151	18	+	28162770	OCIAML2	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	0.7924045805916327	[34]	[335]	7	hSpCas9	negative selection	12291514
31592929	31592952	18	+	28162770	OCIAML2	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.3258367806727068	[18]	[131]	3	hSpCas9	negative selection	12291515
31595234	31595257	18	+	28162770	OCIAML2	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.09461421479250154	[88]	[461]	-1	hSpCas9	negative selection	12291516
31592956	31592979	18	-	28162770	OCIAML2	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.28069106190111515	[29]	[201]	2	hSpCas9	negative selection	12291517
31592972	31592995	18	-	28162770	OCIAML2	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	0.6831755108368742	[9]	[88]	6	hSpCas9	negative selection	12291518
31595144	31595167	18	+	28162770	OCIAML3	viability	GCATGGGCTCACAACTGAGGAGG	TTR	ENSG00000118271	1.2462119156390676	[30]	[221]	8	hSpCas9	negative selection	12460875
31595157	31595180	18	+	28162770	OCIAML3	viability	ACTGAGGAGGAATTTGTAGAAGG	TTR	ENSG00000118271	-0.15588652793227797	[61]	[167]	-1	hSpCas9	negative selection	12460876
31591926	31591949	18	-	28162770	OCIAML3	viability	ATACCAGTCCAGCAAGGCAGAGG	TTR	ENSG00000118271	0.5448904654975246	[93]	[413]	5	hSpCas9	negative selection	12460877
31592987	31593010	18	+	28162770	OCIAML3	viability	GAAAGGCTGCTGATGACACCTGG	TTR	ENSG00000118271	0.1960692903016055	[47]	[165]	1	hSpCas9	negative selection	12460878
31592946	31592969	18	-	28162770	OCIAML3	viability	CATTGATGGCAGGACTGCCTCGG	TTR	ENSG00000118271	0.25244710142238125	[51]	[186]	2	hSpCas9	negative selection	12460879
31595128	31595151	18	+	28162770	OCIAML3	viability	GTGAGTCTGGAGAGCTGCATGGG	TTR	ENSG00000118271	-0.6112856317559987	[41]	[82]	-5	hSpCas9	negative selection	12460880
31592929	31592952	18	+	28162770	OCIAML3	viability	AAAGTTCTAGATGCTGTCCGAGG	TTR	ENSG00000118271	0.4999685078848506	[25]	[110]	4	hSpCas9	negative selection	12460881
31595234	31595257	18	+	28162770	OCIAML3	viability	CCCATTCCATGAGCATGCAGAGG	TTR	ENSG00000118271	-0.2720795454368008	[101]	[254]	-2	hSpCas9	negative selection	12460882
31592956	31592979	18	-	28162770	OCIAML3	viability	TGCACGGCCACATTGATGGCAGG	TTR	ENSG00000118271	0.18687507037224976	[54]	[188]	1	hSpCas9	negative selection	12460883
31592972	31592995	18	-	28162770	OCIAML3	viability	AGCCTTTCTGAACACATGCACGG	TTR	ENSG00000118271	1.0689573723982662	[5]	[37]	8	hSpCas9	negative selection	12460884