Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 6908
• Symbol: Tbp
• Description: TATA-box binding protein

DataSource: http://genomecrispr.dkfz.de/#!/results/Tbp

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
170566941	170566964	6	+	26472758	Jiyoye	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.592824618494127	[47]	[2]	-9	hSpCas9	negative selection	162529
170562223	170562246	6	-	26472758	Jiyoye	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.0906545274893085	[256]	[90]	-6	hSpCas9	negative selection	162530
170562077	170562100	6	-	26472758	Jiyoye	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-1.3147227645713908	[253]	[76]	-7	hSpCas9	negative selection	162531
170564592	170564615	6	-	26472758	Jiyoye	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4169747830947089	[107]	[60]	-3	hSpCas9	negative selection	162532
170566958	170566981	6	-	26472758	Jiyoye	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.886555821550837	[75]	[30]	-6	hSpCas9	negative selection	162533
170561795	170561818	6	-	26472758	Jiyoye	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.33079873772124846	[476]	[285]	-2	hSpCas9	negative selection	162534
170561812	170561835	6	-	26472758	Jiyoye	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.025466058293093896	[270]	[207]	0	hSpCas9	negative selection	162535
170562061	170562084	6	+	26472758	Jiyoye	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.23025453910941854	[153]	[98]	-2	hSpCas9	negative selection	162536
170562091	170562114	6	-	26472758	Jiyoye	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.07165876835393933	[130]	[93]	0	hSpCas9	negative selection	162537
170562191	170562214	6	-	26472758	Jiyoye	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-2.3733379283330898	[212]	[30]	-8	hSpCas9	negative selection	162538
170566941	170566964	6	+	26472758	KBM7	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.261713152931306	[375,188]	[4,20]	-9	hSpCas9	negative selection	353647
170562223	170562246	6	-	26472758	KBM7	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.7370808775411772	[977,919]	[264,270]	-6	hSpCas9	negative selection	353648
170562077	170562100	6	-	26472758	KBM7	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.15281762749139488	[793,632]	[313,286]	-1	hSpCas9	negative selection	353649
170564592	170564615	6	-	26472758	KBM7	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	0.15273718173835898	[371,402]	[291,125]	1	hSpCas9	negative selection	353650
170566958	170566981	6	-	26472758	KBM7	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.5117031691180112	[234,106]	[123,98]	5	hSpCas9	negative selection	353651
170561795	170561818	6	-	26472758	KBM7	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.052645813831524224	[1424,998]	[690,486]	0	hSpCas9	negative selection	353652
170561812	170561835	6	-	26472758	KBM7	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.26036254908309364	[722,1050]	[512,509]	2	hSpCas9	negative selection	353653
170562061	170562084	6	+	26472758	KBM7	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.07744174306956164	[505,639]	[287,289]	0	hSpCas9	negative selection	353654
170562091	170562114	6	-	26472758	KBM7	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.10246439307124111	[821,652]	[336,398]	1	hSpCas9	negative selection	353655
170562191	170562214	6	-	26472758	KBM7	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.28557909290804084	[446,414]	[195,139]	-3	hSpCas9	negative selection	353656
170566941	170566964	6	+	26472758	Raji	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.4974785227852623	[145]	[2]	-9	hSpCas9	negative selection	544765
170562223	170562246	6	-	26472758	Raji	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.8766159859326852	[537]	[67]	-6	hSpCas9	negative selection	544766
170562077	170562100	6	-	26472758	Raji	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.35204808326369774	[395]	[71]	-3	hSpCas9	negative selection	544767
170564592	170564615	6	-	26472758	Raji	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.5635521884574094	[120]	[18]	-4	hSpCas9	negative selection	544768
170566958	170566981	6	-	26472758	Raji	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.6328571908254674	[146]	[10]	-8	hSpCas9	negative selection	544769
170561795	170561818	6	-	26472758	Raji	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.21227080799364195	[633]	[126]	-2	hSpCas9	negative selection	544770
170561812	170561835	6	-	26472758	Raji	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.7752595139882418	[530]	[71]	-5	hSpCas9	negative selection	544771
170562061	170562084	6	+	26472758	Raji	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.44281354718688	[245]	[41]	-4	hSpCas9	negative selection	544772
170562091	170562114	6	-	26472758	Raji	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-1.0055105210323338	[371]	[42]	-6	hSpCas9	negative selection	544773
170562191	170562214	6	-	26472758	Raji	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.5955202227189735	[292]	[44]	-5	hSpCas9	negative selection	544774
170566941	170566964	6	+	26472758	K562	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-6.294740083441585	[185]	[1]	-9	hSpCas9	negative selection	735883
170562223	170562246	6	-	26472758	K562	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.6381165975929818	[836]	[453]	-4	hSpCas9	negative selection	735884
170562077	170562100	6	-	26472758	K562	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-2.294119435963357	[580]	[99]	-8	hSpCas9	negative selection	735885
170564592	170564615	6	-	26472758	K562	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7095527412891482	[400]	[206]	-4	hSpCas9	negative selection	735886
170566958	170566981	6	-	26472758	K562	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.7853286157276052	[146]	[35]	-7	hSpCas9	negative selection	735887
170561795	170561818	6	-	26472758	K562	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.6688617331797433	[1031]	[1384]	5	hSpCas9	negative selection	735888
170561812	170561835	6	-	26472758	K562	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.20908565455416606	[743]	[725]	1	hSpCas9	negative selection	735889
170562061	170562084	6	+	26472758	K562	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.6374778578497959	[462]	[607]	5	hSpCas9	negative selection	735890
170562091	170562114	6	-	26472758	K562	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.05543624382343215	[561]	[492]	0	hSpCas9	negative selection	735891
170562191	170562214	6	-	26472758	K562	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.5636394335183594	[512]	[292]	-4	hSpCas9	negative selection	735892
170557051	170557074	6	-	26627737	DLD1	viability	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.5523971369959141	[244]	[79,20,53]	-5	hSpCas9	negative selection	831376
170562066	170562089	6	+	26627737	DLD1	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-1.7994853398811594	[413]	[5,34,65]	-8	hSpCas9	negative selection	831377
170562127	170562150	6	-	26627737	DLD1	viability	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-2.899803199645632	[677]	[58,20,7]	-9	hSpCas9	negative selection	831378
170562128	170562151	6	-	26627737	DLD1	viability	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.4517556537239065	[977]	[126,138,75]	-8	hSpCas9	negative selection	831379
170569750	170569773	6	-	26627737	DLD1	viability	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-3.233534401795773	[434]	[17,26,0]	-9	hSpCas9	negative selection	831380
170557051	170557074	6	-	26627737	GBM cells	viability after 5 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.5330424324107262	[124]	[102,90]	7	hSpCas9	negative selection	913691
170562066	170562089	6	+	26627737	GBM cells	viability after 5 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.11009490426550886	[202]	[139,94]	1	hSpCas9	negative selection	913692
170562127	170562150	6	-	26627737	GBM cells	viability after 5 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-0.7651201968266693	[224]	[80,60]	-8	hSpCas9	negative selection	913693
170562128	170562151	6	-	26627737	GBM cells	viability after 5 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-0.33255045194723853	[451]	[207,176]	-5	hSpCas9	negative selection	913694
170569750	170569773	6	-	26627737	GBM cells	viability after 5 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.45271544412038117	[155]	[111,116]	6	hSpCas9	negative selection	913695
170557051	170557074	6	-	26627737	GBM cells	viability after 13 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.11801035138937688	[124]	[109,43]	1	hSpCas9	negative selection	996006
170562066	170562089	6	+	26627737	GBM cells	viability after 13 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.2547212266982062	[202]	[104,81]	-3	hSpCas9	negative selection	996007
170562127	170562150	6	-	26627737	GBM cells	viability after 13 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.1468507986008385	[224]	[42,64]	-8	hSpCas9	negative selection	996008
170562128	170562151	6	-	26627737	GBM cells	viability after 13 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.29061741238182	[451]	[118,84]	-8	hSpCas9	negative selection	996009
170569750	170569773	6	-	26627737	GBM cells	viability after 13 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.6223290469082403	[155]	[169,97]	7	hSpCas9	negative selection	996010
170557051	170557074	6	-	26627737	GBM cells	viability after 21 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.17455833208475013	[124]	[84,68]	1	hSpCas9	negative selection	1078321
170562066	170562089	6	+	26627737	GBM cells	viability after 21 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.615177616127206	[202]	[17,17]	-9	hSpCas9	negative selection	1078322
170562127	170562150	6	-	26627737	GBM cells	viability after 21 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.5775606323003402	[224]	[41,39]	-8	hSpCas9	negative selection	1078323
170562128	170562151	6	-	26627737	GBM cells	viability after 21 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-2.836075065027577	[451]	[36,31]	-9	hSpCas9	negative selection	1078324
170569750	170569773	6	-	26627737	GBM cells	viability after 21 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-0.11812353956788835	[155]	[75,79]	-1	hSpCas9	negative selection	1078325
170557051	170557074	6	-	26627737	RPE1	viability after 9 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.16929871806510674	[673]	[252,216]	1	hSpCas9	negative selection	1160636
170562066	170562089	6	+	26627737	RPE1	viability after 9 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.335345623429447	[1715]	[112,97]	-9	hSpCas9	negative selection	1160637
170562127	170562150	6	-	26627737	RPE1	viability after 9 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-4.187555111671934	[522]	[1,17]	-9	hSpCas9	negative selection	1160638
170562128	170562151	6	-	26627737	RPE1	viability after 9 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-0.18264056024444653	[406]	[27,220]	-1	hSpCas9	negative selection	1160639
170569750	170569773	6	-	26627737	RPE1	viability after 9 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-2.6653611584162658	[259]	[21,0]	-9	hSpCas9	negative selection	1160640
170557051	170557074	6	-	26627737	RPE1	viability after 12 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.08916397820415711	[673]	[160,179]	0	hSpCas9	negative selection	1242951
170562066	170562089	6	+	26627737	RPE1	viability after 12 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.9737849764531794	[1715]	[98,15]	-9	hSpCas9	negative selection	1242952
170562127	170562150	6	-	26627737	RPE1	viability after 12 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-3.119180498686888	[522]	[4,27]	-9	hSpCas9	negative selection	1242953
170562128	170562151	6	-	26627737	RPE1	viability after 12 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-0.2613597519679818	[406]	[81,100]	-2	hSpCas9	negative selection	1242954
170569750	170569773	6	-	26627737	RPE1	viability after 12 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-2.783864203908238	[259]	[14,4]	-9	hSpCas9	negative selection	1242955
170557051	170557074	6	-	26627737	RPE1	viability after 15 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.1936359683720857	[673]	[210,123]	-1	hSpCas9	negative selection	1325266
170562066	170562089	6	+	26627737	RPE1	viability after 15 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.9047903612141344	[1715]	[46,81]	-9	hSpCas9	negative selection	1325267
170562127	170562150	6	-	26627737	RPE1	viability after 15 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-3.230498973812517	[522]	[0,29]	-9	hSpCas9	negative selection	1325268
170562128	170562151	6	-	26627737	RPE1	viability after 15 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-0.14572379234326216	[406]	[71,134]	-1	hSpCas9	negative selection	1325269
170569750	170569773	6	-	26627737	RPE1	viability after 15 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-6.20061893915656	[259]	[0,0]	-9	hSpCas9	negative selection	1325270
170557051	170557074	6	-	26627737	RPE1	viability after 18 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.38733529470590977	[673]	[278,193]	2	hSpCas9	negative selection	1407581
170562066	170562089	6	+	26627737	RPE1	viability after 18 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.5063954764324126	[1715]	[66,96]	-8	hSpCas9	negative selection	1407582
170562127	170562150	6	-	26627737	RPE1	viability after 18 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-4.276196615162613	[522]	[0,13]	-9	hSpCas9	negative selection	1407583
170562128	170562151	6	-	26627737	RPE1	viability after 18 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	0.2936937321482821	[406]	[21,254]	2	hSpCas9	negative selection	1407584
170569750	170569773	6	-	26627737	RPE1	viability after 18 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-6.132699552927711	[259]	[0,0]	-9	hSpCas9	negative selection	1407585
170557051	170557074	6	-	26627737	HeLa	viability after 8 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.11181871632194551	[182]	[155,67,51]	1	hSpCas9	negative selection	1489896
170562066	170562089	6	+	26627737	HeLa	viability after 8 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.8311562721541659	[426]	[84,133,90]	-7	hSpCas9	negative selection	1489897
170562127	170562150	6	-	26627737	HeLa	viability after 8 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.95429428616612	[516]	[138,24,29]	-9	hSpCas9	negative selection	1489898
170562128	170562151	6	-	26627737	HeLa	viability after 8 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.015014067052666	[967]	[245,259,132]	-8	hSpCas9	negative selection	1489899
170569750	170569773	6	-	26627737	HeLa	viability after 8 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	1.3863804743021246	[155]	[259,119,170]	8	hSpCas9	negative selection	1489900
170557051	170557074	6	-	26627737	HeLa	viability after 12 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.07220280670065615	[182]	[82,75,79]	0	hSpCas9	negative selection	1572211
170562066	170562089	6	+	26627737	HeLa	viability after 12 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.6985559119347744	[426]	[77,139,103]	-6	hSpCas9	negative selection	1572212
170562127	170562150	6	-	26627737	HeLa	viability after 12 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-2.383153621776722	[516]	[5,48,65]	-9	hSpCas9	negative selection	1572213
170562128	170562151	6	-	26627737	HeLa	viability after 12 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-0.6231273263488967	[967]	[307,170,310]	-5	hSpCas9	negative selection	1572214
170569750	170569773	6	-	26627737	HeLa	viability after 12 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.8029213324771654	[155]	[60,158,110]	6	hSpCas9	negative selection	1572215
170557051	170557074	6	-	26627737	HeLa	viability after 15 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.16371817289974544	[182]	[31,88,79]	-1	hSpCas9	negative selection	1654526
170562066	170562089	6	+	26627737	HeLa	viability after 15 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.04849509170160217	[426]	[143,140,260]	0	hSpCas9	negative selection	1654527
170562127	170562150	6	-	26627737	HeLa	viability after 15 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.8273518762060328	[516]	[34,122,16]	-9	hSpCas9	negative selection	1654528
170562128	170562151	6	-	26627737	HeLa	viability after 15 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.2227283050264128	[967]	[180,112,215]	-8	hSpCas9	negative selection	1654529
170569750	170569773	6	-	26627737	HeLa	viability after 15 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.07548668184940821	[155]	[60,82,55]	0	hSpCas9	negative selection	1654530
170557051	170557074	6	-	26627737	HeLa	viability after 18 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.1506891015040137	[182]	[19,76,79]	-1	hSpCas9	negative selection	1736841
170562066	170562089	6	+	26627737	HeLa	viability after 18 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.04179344305821091	[426]	[97,112,260]	0	hSpCas9	negative selection	1736842
170562127	170562150	6	-	26627737	HeLa	viability after 18 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.7874106700621653	[516]	[20,108,16]	-9	hSpCas9	negative selection	1736843
170562128	170562151	6	-	26627737	HeLa	viability after 18 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.2178987043479708	[967]	[118,97,215]	-8	hSpCas9	negative selection	1736844
170569750	170569773	6	-	26627737	HeLa	viability after 18 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.07648467323090236	[155]	[39,69,55]	0	hSpCas9	negative selection	1736845
170557051	170557074	6	-	26627737	HCT116	viability after 6 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.4883019062566314	[276]	[41,24]	-3	hSpCas9	negative selection	1819156
170562066	170562089	6	+	26627737	HCT116	viability after 6 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-1.2586728310211237	[488]	[64,13]	-6	hSpCas9	negative selection	1819157
170562127	170562150	6	-	26627737	HCT116	viability after 6 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	0.932884959887195	[358]	[41,143]	5	hSpCas9	negative selection	1819158
170562128	170562151	6	-	26627737	HCT116	viability after 6 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	1.6848451970836047	[832]	[955,125]	8	hSpCas9	negative selection	1819159
170569750	170569773	6	-	26627737	HCT116	viability after 6 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-2.0251761018003656	[515]	[46,4]	-8	hSpCas9	negative selection	1819160
170557051	170557074	6	-	26627737	HCT116	viability after 8 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.7601628588596471	[320]	[117,45,148]	-7	hSpCas9	negative selection	1901471
170562066	170562089	6	+	26627737	HCT116	viability after 8 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	1.118060527762957	[117]	[131,130,159]	8	hSpCas9	negative selection	1901472
170562127	170562150	6	-	26627737	HCT116	viability after 8 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	0.5968465811612127	[161]	[71,122,207]	6	hSpCas9	negative selection	1901473
170562128	170562151	6	-	26627737	HCT116	viability after 8 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.7575482474808186	[658]	[147,74,99]	-9	hSpCas9	negative selection	1901474
170569750	170569773	6	-	26627737	HCT116	viability after 8 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-0.163880744508078	[198]	[111,92,88]	-2	hSpCas9	negative selection	1901475
170557051	170557074	6	-	26627737	HCT116	viability after 9 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	1.6453017160155607	[276]	[141,301]	8	hSpCas9	negative selection	1983786
170562066	170562089	6	+	26627737	HCT116	viability after 9 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.3312636136191967	[488]	[35,17]	-9	hSpCas9	negative selection	1983787
170562127	170562150	6	-	26627737	HCT116	viability after 9 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-0.062682844545494	[358]	[131,59]	0	hSpCas9	negative selection	1983788
170562128	170562151	6	-	26627737	HCT116	viability after 9 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	0.4959884086392953	[832]	[516,152]	3	hSpCas9	negative selection	1983789
170569750	170569773	6	-	26627737	HCT116	viability after 9 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-3.3326972350044253	[515]	[11,14]	-9	hSpCas9	negative selection	1983790
170557051	170557074	6	-	26627737	HCT116	viability after 12 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.7333327355017694	[320]	[119,68,112]	-7	hSpCas9	negative selection	2066101
170562066	170562089	6	+	26627737	HCT116	viability after 12 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.011806856933835208	[117]	[30,89,69]	0	hSpCas9	negative selection	2066102
170562127	170562150	6	-	26627737	HCT116	viability after 12 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	0.30205987355336794	[161]	[18,127,175]	3	hSpCas9	negative selection	2066103
170562128	170562151	6	-	26627737	HCT116	viability after 12 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.2875979644179025	[658]	[201,128,88]	-8	hSpCas9	negative selection	2066104
170569750	170569773	6	-	26627737	HCT116	viability after 12 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.10251366805381029	[198]	[160,88,81]	1	hSpCas9	negative selection	2066105
170557051	170557074	6	-	26627737	HCT116	viability after 15 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.7961444757376969	[320]	[144,53,123]	-7	hSpCas9	negative selection	2148416
170562066	170562089	6	+	26627737	HCT116	viability after 15 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.2729233956845938	[117]	[54,157,29]	2	hSpCas9	negative selection	2148417
170562127	170562150	6	-	26627737	HCT116	viability after 15 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	0.07121516956135521	[161]	[59,77,149]	0	hSpCas9	negative selection	2148418
170562128	170562151	6	-	26627737	HCT116	viability after 15 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.2609755253443247	[658]	[172,178,123]	-8	hSpCas9	negative selection	2148419
170569750	170569773	6	-	26627737	HCT116	viability after 15 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-0.3301441750570322	[198]	[105,113,54]	-3	hSpCas9	negative selection	2148420
170557051	170557074	6	-	26627737	HCT116	viability after 18 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-1.231129149549748	[320]	[61,61,74]	-8	hSpCas9	negative selection	2230731
170562066	170562089	6	+	26627737	HCT116	viability after 18 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.2034137985367328	[117]	[31,79,84]	1	hSpCas9	negative selection	2230732
170562127	170562150	6	-	26627737	HCT116	viability after 18 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	0.636961580557744	[161]	[95,126,142]	5	hSpCas9	negative selection	2230733
170562128	170562151	6	-	26627737	HCT116	viability after 18 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-2.0443025501844736	[658]	[78,56,97]	-9	hSpCas9	negative selection	2230734
170569750	170569773	6	-	26627737	HCT116	viability after 18 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.1812963091389853	[198]	[76,115,134]	1	hSpCas9	negative selection	2230735
170561785	170561808	6	+	24336569	HL60	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	0.7454486678195084	[156]	[556]	6	hSpCas9	negative selection	2299161
170561795	170561818	6	-	24336569	HL60	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.2725945379692938	[543]	[952]	-2	hSpCas9	negative selection	2299162
170561803	170561826	6	-	24336569	HL60	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	0.372801795054885	[584]	[1602]	3	hSpCas9	negative selection	2299163
170561811	170561834	6	-	24336569	HL60	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.2994284886930646	[325]	[848]	3	hSpCas9	negative selection	2299164
170561818	170561841	6	+	24336569	HL60	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	-0.35191597802517327	[233]	[387]	-3	hSpCas9	negative selection	2299165
170561824	170561847	6	-	24336569	HL60	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	0.6492152306898787	[206]	[686]	5	hSpCas9	negative selection	2299166
170561853	170561876	6	-	24336569	HL60	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	0.04758654214452984	[886]	[1939]	0	hSpCas9	negative selection	2299167
170561860	170561883	6	-	24336569	HL60	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	-0.19671619593853878	[533]	[985]	-2	hSpCas9	negative selection	2299168
170562038	170562061	6	-	24336569	HL60	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.38984997414869627	[781]	[1262]	-3	hSpCas9	negative selection	2299169
170562051	170562074	6	+	24336569	HL60	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	0.980653065575024	[607]	[2538]	7	hSpCas9	negative selection	2299170
170561785	170561808	6	+	24336569	KBM7	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	0.8655786887107477	[131]	[655]	7	hSpCas9	negative selection	2366338
170561795	170561818	6	-	24336569	KBM7	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.6264005984795912	[548]	[969]	-5	hSpCas9	negative selection	2366339
170561803	170561826	6	-	24336569	KBM7	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	-1.1958810245429898	[723]	[861]	-7	hSpCas9	negative selection	2366340
170561811	170561834	6	-	24336569	KBM7	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.13643477737476112	[375]	[932]	-1	hSpCas9	negative selection	2366341
170561818	170561841	6	+	24336569	KBM7	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	-0.11868715391175577	[247]	[622]	-1	hSpCas9	negative selection	2366342
170561824	170561847	6	-	24336569	KBM7	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	-0.21870538981678603	[348]	[817]	-2	hSpCas9	negative selection	2366343
170561853	170561876	6	-	24336569	KBM7	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-0.09318540410918641	[579]	[1482]	-1	hSpCas9	negative selection	2366344
170561860	170561883	6	-	24336569	KBM7	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	2.589619421405367	[66]	[1099]	9	hSpCas9	negative selection	2366345
170562038	170562061	6	-	24336569	KBM7	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-1.250007947298473	[401]	[460]	-7	hSpCas9	negative selection	2366346
170562051	170562074	6	+	24336569	KBM7	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	0.3114708384562618	[563]	[1908]	3	hSpCas9	negative selection	2366347
170558785	170558808	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACACGG	TBP	ENSG00000112592	6.121120684117956	[31,90]	[7,1976]	9	dCas9-VP64	positive selection	2387422
170558785	170558808	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACACGG	TBP	ENSG00000112592	1.1434369151352513	[54,74]	[73,20]	7	dCas9-VP64	positive selection	2482677
170561795	170561818	6	-	27260157	DLD1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.384719346303045	[]	[]	-3	hSpCas9	negative selection	2576986
170561818	170561841	6	+	27260157	DLD1	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	-0.147255959973359	[]	[]	-1	hSpCas9	negative selection	2578448
170561860	170561883	6	-	27260157	DLD1	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	-2.27166388330014	[]	[]	-9	hSpCas9	negative selection	2579949
170561811	170561834	6	-	27260157	DLD1	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.103545666891032	[]	[]	0	hSpCas9	negative selection	2585001
170561853	170561876	6	-	27260157	DLD1	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-1.709087923832	[]	[]	-8	hSpCas9	negative selection	2604472
170562102	170562125	6	-	27260157	DLD1	viability	CAGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-2.09339193336798	[]	[]	-8	hSpCas9	negative selection	2605953
170561852	170561875	6	-	27260157	DLD1	viability	GGTGTTCTGAATAGGCTGTGGGG	TBP	ENSG00000112592	-0.967913486310772	[]	[]	-7	hSpCas9	negative selection	2606836
170562052	170562075	6	+	27260157	DLD1	viability	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-1.22202844648346	[]	[]	-7	hSpCas9	negative selection	2607098
170557047	170557070	6	-	27260157	DLD1	viability	AGCCCTGAGCGTAAGGTGGCAGG	TBP	ENSG00000112592	-0.0834387840267674	[]	[]	0	hSpCas9	negative selection	2609167
170562038	170562061	6	-	27260157	DLD1	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-1.29806232626461	[]	[]	-7	hSpCas9	negative selection	2613430
170562066	170562089	6	+	27260157	DLD1	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.920300313532621	[]	[]	-6	hSpCas9	negative selection	2613571
170557044	170557067	6	+	27260157	DLD1	viability	CAGCCTGCCACCTTACGCTCAGG	TBP	ENSG00000112592	1.1900986115988	[]	[]	9	hSpCas9	negative selection	2613935
170562051	170562074	6	+	27260157	DLD1	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	-0.805180224247973	[]	[]	-6	hSpCas9	negative selection	2614693
170562056	170562079	6	-	27260157	DLD1	viability	GGTTCCCTGTGTTGCCTGCTGGG	TBP	ENSG00000112592	-1.01284819388762	[]	[]	-7	hSpCas9	negative selection	2615189
170561785	170561808	6	+	27260157	DLD1	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	-0.934643678691262	[]	[]	-6	hSpCas9	negative selection	2619657
170562042	170562065	6	+	27260157	DLD1	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.975843168228622	[]	[]	-7	hSpCas9	negative selection	2622769
170561824	170561847	6	+	27260157	DLD1	viability	CCAATGATGCCTTATGGCACTGG	TBP	ENSG00000112592	-0.447746138378107	[]	[]	-4	hSpCas9	negative selection	2623932
170561803	170561826	6	-	27260157	DLD1	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	0.317452409661945	[]	[]	4	hSpCas9	negative selection	2645766
170557076	170557099	6	-	27260157	DLD1	viability	CTCCTGCTATATTACCTGAGGGG	TBP	ENSG00000112592	0.666508430652821	[]	[]	8	hSpCas9	negative selection	2646787
170561824	170561847	6	-	27260157	DLD1	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	-0.992399459910307	[]	[]	-7	hSpCas9	negative selection	2647498
170561795	170561818	6	-	27260157	HT1080	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.549458135223268	[]	[]	-7	hSpCas9	negative selection	2653116
170561818	170561841	6	+	27260157	HT1080	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	0.357291882467349	[]	[]	3	hSpCas9	negative selection	2654578
170561860	170561883	6	-	27260157	HT1080	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	0.0909453720994746	[]	[]	1	hSpCas9	negative selection	2656079
170561811	170561834	6	-	27260157	HT1080	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.785055976708058	[]	[]	7	hSpCas9	negative selection	2661131
170561853	170561876	6	-	27260157	HT1080	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-2.15694264495971	[]	[]	-9	hSpCas9	negative selection	2680602
170562102	170562125	6	-	27260157	HT1080	viability	CAGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-1.1207908088173	[]	[]	-8	hSpCas9	negative selection	2682083
170561852	170561875	6	-	27260157	HT1080	viability	GGTGTTCTGAATAGGCTGTGGGG	TBP	ENSG00000112592	-2.09064467182981	[]	[]	-9	hSpCas9	negative selection	2682966
170562052	170562075	6	+	27260157	HT1080	viability	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-0.464202921791944	[]	[]	-7	hSpCas9	negative selection	2683228
170557047	170557070	6	-	27260157	HT1080	viability	AGCCCTGAGCGTAAGGTGGCAGG	TBP	ENSG00000112592	0.242073732196656	[]	[]	2	hSpCas9	negative selection	2685297
170562038	170562061	6	-	27260157	HT1080	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-1.43970534860722	[]	[]	-9	hSpCas9	negative selection	2689560
170562066	170562089	6	+	27260157	HT1080	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.000553107565926968	[]	[]	0	hSpCas9	negative selection	2689701
170557044	170557067	6	+	27260157	HT1080	viability	CAGCCTGCCACCTTACGCTCAGG	TBP	ENSG00000112592	0.760677324483172	[]	[]	6	hSpCas9	negative selection	2690065
170562051	170562074	6	+	27260157	HT1080	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	-1.81711258616324	[]	[]	-9	hSpCas9	negative selection	2690823
170562056	170562079	6	-	27260157	HT1080	viability	GGTTCCCTGTGTTGCCTGCTGGG	TBP	ENSG00000112592	-2.04378607023827	[]	[]	-9	hSpCas9	negative selection	2691319
170561785	170561808	6	+	27260157	HT1080	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	-0.198428499531126	[]	[]	0	hSpCas9	negative selection	2695787
170562042	170562065	6	+	27260157	HT1080	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.802760795474627	[]	[]	7	hSpCas9	negative selection	2698899
170561824	170561847	6	+	27260157	HT1080	viability	CCAATGATGCCTTATGGCACTGG	TBP	ENSG00000112592	-0.0734987278954278	[]	[]	0	hSpCas9	negative selection	2700062
170561803	170561826	6	-	27260157	HT1080	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	0.602790359487619	[]	[]	5	hSpCas9	negative selection	2721896
170557076	170557099	6	-	27260157	HT1080	viability	CTCCTGCTATATTACCTGAGGGG	TBP	ENSG00000112592	-0.37607449382138	[]	[]	-7	hSpCas9	negative selection	2722917
170561824	170561847	6	-	27260157	HT1080	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	0.138825212201558	[]	[]	1	hSpCas9	negative selection	2723628
170561795	170561818	6	-	27260157	MKN45	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-2.32875413790422	[]	[]	-9	hSpCas9	negative selection	2729246
170561818	170561841	6	+	27260157	MKN45	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	0.327331353021944	[]	[]	6	hSpCas9	negative selection	2730708
170561860	170561883	6	-	27260157	MKN45	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	-1.75044154024569	[]	[]	-9	hSpCas9	negative selection	2732209
170561811	170561834	6	-	27260157	MKN45	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.872453605934777	[]	[]	-7	hSpCas9	negative selection	2737261
170561853	170561876	6	-	27260157	MKN45	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-2.16240092457947	[]	[]	-9	hSpCas9	negative selection	2756732
170562102	170562125	6	-	27260157	MKN45	viability	CAGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-1.32533084390093	[]	[]	-8	hSpCas9	negative selection	2758213
170561852	170561875	6	-	27260157	MKN45	viability	GGTGTTCTGAATAGGCTGTGGGG	TBP	ENSG00000112592	-2.32082672748049	[]	[]	-9	hSpCas9	negative selection	2759096
170562052	170562075	6	+	27260157	MKN45	viability	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-1.37434773003597	[]	[]	-8	hSpCas9	negative selection	2759358
170557047	170557070	6	-	27260157	MKN45	viability	AGCCCTGAGCGTAAGGTGGCAGG	TBP	ENSG00000112592	-0.358907518275621	[]	[]	-1	hSpCas9	negative selection	2761427
170562038	170562061	6	-	27260157	MKN45	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.884998649770968	[]	[]	-7	hSpCas9	negative selection	2765690
170562066	170562089	6	+	27260157	MKN45	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-1.41915103280023	[]	[]	-8	hSpCas9	negative selection	2765831
170557044	170557067	6	+	27260157	MKN45	viability	CAGCCTGCCACCTTACGCTCAGG	TBP	ENSG00000112592	0.379838878542219	[]	[]	6	hSpCas9	negative selection	2766195
170562051	170562074	6	+	27260157	MKN45	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	-0.606060865949173	[]	[]	-6	hSpCas9	negative selection	2766953
170562056	170562079	6	-	27260157	MKN45	viability	GGTTCCCTGTGTTGCCTGCTGGG	TBP	ENSG00000112592	-1.34215451280739	[]	[]	-8	hSpCas9	negative selection	2767449
170561785	170561808	6	+	27260157	MKN45	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	-1.61991190601109	[]	[]	-9	hSpCas9	negative selection	2771917
170562042	170562065	6	+	27260157	MKN45	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.205857508962572	[]	[]	5	hSpCas9	negative selection	2775029
170561824	170561847	6	+	27260157	MKN45	viability	CCAATGATGCCTTATGGCACTGG	TBP	ENSG00000112592	-1.32677514127479	[]	[]	-8	hSpCas9	negative selection	2776192
170561803	170561826	6	-	27260157	MKN45	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	-0.749067137732779	[]	[]	-7	hSpCas9	negative selection	2798026
170557076	170557099	6	-	27260157	MKN45	viability	CTCCTGCTATATTACCTGAGGGG	TBP	ENSG00000112592	-0.447765288935801	[]	[]	-6	hSpCas9	negative selection	2799047
170561824	170561847	6	-	27260157	MKN45	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	-2.09029864081234	[]	[]	-9	hSpCas9	negative selection	2799758
170561795	170561818	6	-	27260157	RKO	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.896332718812362	[]	[]	-8	hSpCas9	negative selection	2805376
170561818	170561841	6	+	27260157	RKO	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	0.636266813688726	[]	[]	3	hSpCas9	negative selection	2806838
170561860	170561883	6	-	27260157	RKO	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	-1.84655461646487	[]	[]	-9	hSpCas9	negative selection	2808339
170561811	170561834	6	-	27260157	RKO	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.236514964814441	[]	[]	-1	hSpCas9	negative selection	2813391
170561853	170561876	6	-	27260157	RKO	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-1.90649633037855	[]	[]	-9	hSpCas9	negative selection	2832862
170562102	170562125	6	-	27260157	RKO	viability	CAGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-1.76348181112887	[]	[]	-9	hSpCas9	negative selection	2834343
170561852	170561875	6	-	27260157	RKO	viability	GGTGTTCTGAATAGGCTGTGGGG	TBP	ENSG00000112592	-2.44428697105309	[]	[]	-9	hSpCas9	negative selection	2835226
170562052	170562075	6	+	27260157	RKO	viability	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-0.926705721255681	[]	[]	-8	hSpCas9	negative selection	2835488
170557047	170557070	6	-	27260157	RKO	viability	AGCCCTGAGCGTAAGGTGGCAGG	TBP	ENSG00000112592	0.120588139106342	[]	[]	0	hSpCas9	negative selection	2837557
170562038	170562061	6	-	27260157	RKO	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.892293274199105	[]	[]	-8	hSpCas9	negative selection	2841820
170562066	170562089	6	+	27260157	RKO	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-2.09436475572702	[]	[]	-9	hSpCas9	negative selection	2841961
170557044	170557067	6	+	27260157	RKO	viability	CAGCCTGCCACCTTACGCTCAGG	TBP	ENSG00000112592	-0.163266531634816	[]	[]	-1	hSpCas9	negative selection	2842325
170562051	170562074	6	+	27260157	RKO	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	-0.800128781259996	[]	[]	-7	hSpCas9	negative selection	2843083
170562056	170562079	6	-	27260157	RKO	viability	GGTTCCCTGTGTTGCCTGCTGGG	TBP	ENSG00000112592	-2.22161063452073	[]	[]	-9	hSpCas9	negative selection	2843579
170561785	170561808	6	+	27260157	RKO	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	0.315170486416442	[]	[]	1	hSpCas9	negative selection	2848047
170562042	170562065	6	+	27260157	RKO	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.566946643544625	[]	[]	3	hSpCas9	negative selection	2851159
170561824	170561847	6	+	27260157	RKO	viability	CCAATGATGCCTTATGGCACTGG	TBP	ENSG00000112592	-0.261892117448889	[]	[]	-1	hSpCas9	negative selection	2852322
170561803	170561826	6	-	27260157	RKO	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	-0.611829199528781	[]	[]	-7	hSpCas9	negative selection	2874156
170557076	170557099	6	-	27260157	RKO	viability	CTCCTGCTATATTACCTGAGGGG	TBP	ENSG00000112592	-0.401297394015733	[]	[]	-6	hSpCas9	negative selection	2875177
170561824	170561847	6	-	27260157	RKO	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	-0.999837099129372	[]	[]	-8	hSpCas9	negative selection	2875888
170561795	170561818	6	-	27260157	SF268	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.263049439206312	[]	[]	-2	hSpCas9	negative selection	2881506
170561818	170561841	6	+	27260157	SF268	viability	TTTAGTCCAATGATGCCTTATGG	TBP	ENSG00000112592	0.739604756835271	[]	[]	8	hSpCas9	negative selection	2882968
170561860	170561883	6	-	27260157	SF268	viability	AGACTATTGGTGTTCTGAATAGG	TBP	ENSG00000112592	-0.674469334914235	[]	[]	-5	hSpCas9	negative selection	2884469
170561811	170561834	6	-	27260157	SF268	viability	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.135415153055377	[]	[]	0	hSpCas9	negative selection	2889521
170561853	170561876	6	-	27260157	SF268	viability	TGGTGTTCTGAATAGGCTGTGGG	TBP	ENSG00000112592	-1.27944671841375	[]	[]	-7	hSpCas9	negative selection	2908992
170562102	170562125	6	-	27260157	SF268	viability	CAGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.347874422591224	[]	[]	-3	hSpCas9	negative selection	2910473
170561852	170561875	6	-	27260157	SF268	viability	GGTGTTCTGAATAGGCTGTGGGG	TBP	ENSG00000112592	-1.5231528317286	[]	[]	-8	hSpCas9	negative selection	2911356
170562052	170562075	6	+	27260157	SF268	viability	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-0.959221182593757	[]	[]	-6	hSpCas9	negative selection	2911618
170557047	170557070	6	-	27260157	SF268	viability	AGCCCTGAGCGTAAGGTGGCAGG	TBP	ENSG00000112592	0.00794561845130974	[]	[]	0	hSpCas9	negative selection	2913687
170562038	170562061	6	-	27260157	SF268	viability	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.68638764823776	[]	[]	-5	hSpCas9	negative selection	2917950
170562066	170562089	6	+	27260157	SF268	viability	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-1.35048945353629	[]	[]	-7	hSpCas9	negative selection	2918091
170557044	170557067	6	+	27260157	SF268	viability	CAGCCTGCCACCTTACGCTCAGG	TBP	ENSG00000112592	0.276852437842215	[]	[]	4	hSpCas9	negative selection	2918455
170562051	170562074	6	+	27260157	SF268	viability	AACGTCCCAGCAGGCAACACAGG	TBP	ENSG00000112592	-0.338903771584382	[]	[]	-3	hSpCas9	negative selection	2919213
170562056	170562079	6	-	27260157	SF268	viability	GGTTCCCTGTGTTGCCTGCTGGG	TBP	ENSG00000112592	-0.282187683681243	[]	[]	-2	hSpCas9	negative selection	2919709
170561785	170561808	6	+	27260157	SF268	viability	CCACAGGGTGCCATGACTCCCGG	TBP	ENSG00000112592	-0.107443602335184	[]	[]	-1	hSpCas9	negative selection	2924177
170562042	170562065	6	+	27260157	SF268	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-1.12856779275756	[]	[]	-7	hSpCas9	negative selection	2927289
170561824	170561847	6	+	27260157	SF268	viability	CCAATGATGCCTTATGGCACTGG	TBP	ENSG00000112592	-0.0950139819179656	[]	[]	0	hSpCas9	negative selection	2928452
170561803	170561826	6	-	27260157	SF268	viability	GGACTAAAGATAGGGATTCCGGG	TBP	ENSG00000112592	-0.199425589600935	[]	[]	-1	hSpCas9	negative selection	2950286
170557076	170557099	6	-	27260157	SF268	viability	CTCCTGCTATATTACCTGAGGGG	TBP	ENSG00000112592	-0.371188134341094	[]	[]	-3	hSpCas9	negative selection	2951307
170561824	170561847	6	-	27260157	SF268	viability	CCAGTGCCATAAGGCATCATTGG	TBP	ENSG00000112592	-0.736110342893928	[]	[]	-5	hSpCas9	negative selection	2952018
170562191	170562214	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.2655350432017263	[2,2]	[0,0]	-9	hSpCas9	positive selection	3025737
170562038	170562061	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	0.003432112112100094	[3,3]	[1,4]	0	hSpCas9	positive selection	3025738
170562007	170562030	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	-0.8631356005674373	[2,1]	[1,0]	-8	hSpCas9	positive selection	3025739
170561811	170561834	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.08800359213689579	[5,5]	[3,5]	1	hSpCas9	positive selection	3025740
170562191	170562214	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.05674211728733014	[2,2]	[2,0]	-1	hSpCas9	positive selection	3093595
170562038	170562061	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	0.5644673585962211	[3,3]	[3,4]	8	hSpCas9	positive selection	3093596
170562007	170562030	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	-0.7974328115319802	[2,2]	[1,0]	-9	hSpCas9	positive selection	3093597
170561811	170561834	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.2485217403000543	[5,5]	[5,1]	-4	hSpCas9	positive selection	3093598
170564611	170564634		+	24336571	A375	resistance to PLX after 7 days	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.12135356742363501	[2,2]	[2,2]	-4	hSpCas9	positive selection	3149277
170566908	170566931		+	24336571	A375	resistance to PLX after 7 days	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	0.2994166986191147	[2,3]	[3,3]	7	hSpCas9	positive selection	3149278
170562038	170562061		-	24336571	A375	resistance to PLX after 7 days	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.016701726697453068	[8,6]	[8,6]	0	hSpCas9	positive selection	3149279
170564592	170564615		-	24336571	A375	resistance to PLX after 7 days	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.14779032700729933	[3,3]	[3,2]	-5	hSpCas9	positive selection	3149280
170562042	170562065		+	24336571	A375	resistance to PLX after 7 days	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.09620697053727276	[11,13]	[14,12]	3	hSpCas9	positive selection	3149281
170564611	170564634		+	24336571	A375	resistance to PLX after 14 days	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	0.7039738028991365	[2,2]	[1,1]	6	hSpCas9	positive selection	3207070
170566908	170566931		+	24336571	A375	resistance to PLX after 14 days	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	0.44212845032701664	[2,1]	[1,1]	4	hSpCas9	positive selection	3207071
170562038	170562061		-	24336571	A375	resistance to PLX after 14 days	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.3399474384518091	[7,6]	[1,2]	-4	hSpCas9	positive selection	3207072
170564592	170564615		-	24336571	A375	resistance to PLX after 14 days	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	0.2982463882664439	[3,3]	[1,1]	3	hSpCas9	positive selection	3207073
170562042	170562065		+	24336571	A375	resistance to PLX after 14 days	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.4504913771462622	[17,18]	[6,4]	-5	hSpCas9	positive selection	3207074
170564611	170564634		+	24336571	A375	viability after 7 days	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.0499964426229664	[14]	[2,2]	-9	hSpCas9	negative selection	3264863
170566908	170566931		+	24336571	A375	viability after 7 days	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.5455549399271769	[9]	[2,3]	-9	hSpCas9	negative selection	3264864
170562038	170562061		-	24336571	A375	viability after 7 days	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	1.618965920856474	[1]	[8,6]	9	hSpCas9	negative selection	3264865
170564592	170564615		-	24336571	A375	viability after 7 days	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6956511881549456	[6]	[3,3]	-7	hSpCas9	negative selection	3264866
170562042	170562065		+	24336571	A375	viability after 7 days	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	2.3467756758200164	[1]	[11,13]	9	hSpCas9	negative selection	3264867
170564611	170564634		+	24336571	A375	viability after 14 days	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.2149093387019567	[14]	[2,2]	-9	hSpCas9	negative selection	3322656
170566908	170566931		+	24336571	A375	viability after 14 days	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.5587235706101308	[9]	[2,1]	-9	hSpCas9	negative selection	3322657
170562038	170562061		-	24336571	A375	viability after 14 days	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	1.540109765062403	[1]	[7,6]	9	hSpCas9	negative selection	3322658
170564592	170564615		-	24336571	A375	viability after 14 days	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7237099951795696	[6]	[3,3]	-7	hSpCas9	negative selection	3322659
170562042	170562065		+	24336571	A375	viability after 14 days	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	2.8332181154804945	[1]	[17,18]	9	hSpCas9	negative selection	3322660
170564611	170564634	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	2.087401210003523	[35,35]	[0,0]	7	hSpCas9	positive selection	3396398
170566958	170566981	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	2.5024387092823663	[26,26]	[0,0]	8	hSpCas9	positive selection	3396399
170569733	170569756	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	1.5849008694743394	[50,50]	[0,0]	6	hSpCas9	positive selection	3396400
170562191	170562214	6	-	26780180	HT29	viability (Avana library 4 designs)	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	2.84407156690369	[]	[]	8	hSpCas9	negative selection	3464447
170562038	170562061	6	-	26780180	HT29	viability (Avana library 4 designs)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	3.02897119275347	[]	[]	8	hSpCas9	negative selection	3464448
170562006	170562029	6	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	3.19877684317593	[]	[]	8	hSpCas9	negative selection	3464449
170561811	170561834	6	-	26780180	HT29	viability (Avana library 4 designs)	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.10213172363447	[]	[]	0	hSpCas9	negative selection	3464450
170562038	170562061	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	3.02049540410029	[]	[]	4	hSpCas9	negative selection	3567146
170562006	170562029	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	-3.77444947695173	[]	[]	-4	hSpCas9	negative selection	3567147
170561811	170561834	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-2.81224402782221	[]	[]	-3	hSpCas9	negative selection	3567148
170562191	170562214	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-2.95173979962341	[]	[]	-4	hSpCas9	negative selection	3567149
170562052	170562075	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-2.87657720852035	[]	[]	-3	hSpCas9	negative selection	3567150
170562042	170562065	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.237870386986663	[]	[]	0	hSpCas9	negative selection	3567151
170562038	170562061	6	-	26780180	A375	viability (Avana lentiGuide)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	5.32744223050635	[]	[]	5	hSpCas9	negative selection	3675805
170562006	170562029	6	+	26780180	A375	viability (Avana lentiGuide)	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	8.45100200132774	[]	[]	6	hSpCas9	negative selection	3675806
170561811	170561834	6	-	26780180	A375	viability (Avana lentiGuide)	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-4.43507098485623	[]	[]	-7	hSpCas9	negative selection	3675807
170562191	170562214	6	-	26780180	A375	viability (Avana lentiGuide)	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	7.85751217669618	[]	[]	6	hSpCas9	negative selection	3675808
170562052	170562075	6	+	26780180	A375	viability (Avana lentiGuide)	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	2.08747263611266	[]	[]	2	hSpCas9	negative selection	3675809
170562042	170562065	6	+	26780180	A375	viability (Avana lentiGuide)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	3.44741703687569	[]	[]	3	hSpCas9	negative selection	3675810
170562038	170562061	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.06795629333821762	[4]	[5,3]	-1	hSpCas9	positive selection	3784412
170562006	170562029	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	-0.5595330126646889	[3]	[3,1]	-7	hSpCas9	positive selection	3784413
170561811	170561834	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	-0.5630979346202576	[7]	[5,3]	-7	hSpCas9	positive selection	3784414
170562191	170562214	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.02893209159747484	[4]	[4,3]	0	hSpCas9	positive selection	3784415
170562052	170562075	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-0.47754715588638114	[4]	[3,1]	-6	hSpCas9	positive selection	3784416
170562042	170562065	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.16848615892490432	[5]	[5,4]	-3	hSpCas9	positive selection	3784417
170562038	170562061	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.2999479989562998	[5]	[3,3]	-4	hSpCas9	positive selection	3893019
170562006	170562029	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCAGCAGCAACAGGCAGTGG	TBP	ENSG00000112592	-1.011196295668496	[4]	[0,1]	-8	hSpCas9	positive selection	3893020
170561811	170561834	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCATTGGACTAAAGATAGGG	TBP	ENSG00000112592	0.18704179535978066	[7]	[6,6]	4	hSpCas9	positive selection	3893021
170562191	170562214	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.9052108259709616	[4]	[2,0]	-8	hSpCas9	positive selection	3893022
170562052	170562075	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGTCCCAGCAGGCAACACAGGG	TBP	ENSG00000112592	-0.8755846914189171	[4]	[1,1]	-8	hSpCas9	positive selection	3893023
170562042	170562065	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.1728825168204045	[7]	[7,6]	4	hSpCas9	positive selection	3893024
170564611	170564634	6	+	26780180	A375	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	1.41651002576288	[]	[]	7	hSpCas9	negative selection	4002421
170569733	170569756	6	-	26780180	A375	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.657434369255264	[]	[]	2	hSpCas9	negative selection	4002422
170566908	170566931	6	+	26780180	A375	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	1.74903750575307	[]	[]	9	hSpCas9	negative selection	4002423
170566958	170566981	6	-	26780180	A375	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	1.13831046885564	[]	[]	6	hSpCas9	negative selection	4002424
170564592	170564615	6	-	26780180	A375	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	1.85706868234577	[]	[]	9	hSpCas9	negative selection	4002425
170562042	170562065	6	+	26780180	A375	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	1.95653019145043	[]	[]	9	hSpCas9	negative selection	4002426
170564611	170564634	6	+	26780180	HT29	viability (GeCKOv2 library)	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	1.71775414990569	[]	[]	8	hSpCas9	negative selection	4110387
170569733	170569756	6	-	26780180	HT29	viability (GeCKOv2 library)	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.373970088857566	[]	[]	1	hSpCas9	negative selection	4110388
170566908	170566931	6	+	26780180	HT29	viability (GeCKOv2 library)	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	1.53698259298149	[]	[]	7	hSpCas9	negative selection	4110389
170566958	170566981	6	-	26780180	HT29	viability (GeCKOv2 library)	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	1.62166659046341	[]	[]	8	hSpCas9	negative selection	4110390
170564592	170564615	6	-	26780180	HT29	viability (GeCKOv2 library)	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	2.35135991343329	[]	[]	9	hSpCas9	negative selection	4110391
170562042	170562065	6	+	26780180	HT29	viability (GeCKOv2 library)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	1.2636787180968	[]	[]	6	hSpCas9	negative selection	4110392
170564611	170564634	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.7023417748979585	[2]	[0,0]	-9	hSpCas9	positive selection	4175610
170566908	170566931	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.9155332053568512	[3]	[0,0]	-9	hSpCas9	positive selection	4175611
170562038	170562061	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	-0.7197679900827215	[3]	[0,0]	-9	hSpCas9	positive selection	4175612
170564592	170564615	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.11746483029280586	[1]	[1,0]	-3	hSpCas9	positive selection	4175613
170562042	170562065	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.09059079007561766	[3]	[1,2]	-2	hSpCas9	positive selection	4175614
170564611	170564634	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.9518646678223314	[4]	[0,0,1,0]	-9	hSpCas9	positive selection	4239632
170566908	170566931	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	0.2332554973559655	[3]	[2,0,3,0]	1	hSpCas9	positive selection	4239633
170562038	170562061	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGGACGTTGACTGCTGAACGG	TBP	ENSG00000112592	1.2162448930175256	[3]	[0,2,0,5]	8	hSpCas9	positive selection	4239634
170564592	170564615	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7158656404472961	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4239635
170562042	170562065	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.19699495866504235	[3]	[0,1,2,0]	-3	hSpCas9	positive selection	4239636
170564592	170564615	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.232154706062401	[2]	[0,0]	-9	hSpCas9	positive selection	4302244
170566908	170566931	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.6455915159246617	[3]	[2,0]	-9	hSpCas9	positive selection	4302245
170562042	170562065	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.638847979638264	[2]	[2,0]	-9	hSpCas9	positive selection	4302246
170564611	170564634	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.6653019052617813	[2]	[0,0]	-9	hSpCas9	positive selection	4366498
170566958	170566981	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.4952095930459444	[2]	[0,0]	-8	hSpCas9	positive selection	4366499
170569733	170569756	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.19664484751902916	[1]	[2,0]	4	hSpCas9	positive selection	4366500
170562062	170562084	6	+	27760321	OCIAML3	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.34604401546361263	[452,368]	[244,616]	4	hSpCas9	negative selection	4445664
170562102	170562124	6	-	27760321	OCIAML3	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.014145004811465911	[435,386]	[292,350]	0	hSpCas9	negative selection	4445665
170562191	170562213	6	-	27760321	OCIAML3	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.17842771273770452	[963,813]	[543,700]	-2	hSpCas9	negative selection	4445666
170564592	170564614	6	-	27760321	OCIAML3	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7924309309257596	[74,64]	[34,26]	-6	hSpCas9	negative selection	4445667
170564612	170564634	6	+	27760321	OCIAML3	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.7870972473786526	[212,169]	[20,71]	-9	hSpCas9	negative selection	4445668
170562062	170562084	6	+	27760321	OCIAML2	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.05302007280187157	[452,368]	[298,344]	0	hSpCas9	negative selection	4529127
170562102	170562124	6	-	27760321	OCIAML2	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.32890075975213084	[435,386]	[280,242]	-4	hSpCas9	negative selection	4529128
170562191	170562213	6	-	27760321	OCIAML2	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.6671557057573331	[963,813]	[373,552]	-6	hSpCas9	negative selection	4529129
170564592	170564614	6	-	27760321	OCIAML2	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6629741271846248	[74,64]	[20,54]	-6	hSpCas9	negative selection	4529130
170564612	170564634	6	+	27760321	OCIAML2	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.960483203167737	[212,169]	[39,38]	-9	hSpCas9	negative selection	4529131
170562062	170562084	6	+	27760321	MV411	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.9784496821946089	[452,368]	[613,407]	7	hSpCas9	negative selection	4612590
170562102	170562124	6	-	27760321	MV411	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	0.28783831084850275	[435,386]	[545,7]	2	hSpCas9	negative selection	4612591
170562191	170562213	6	-	27760321	MV411	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	0.38129240898486483	[963,813]	[443,1237]	2	hSpCas9	negative selection	4612592
170564592	170564614	6	-	27760321	MV411	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.9777690436156381	[74,64]	[16,32]	-6	hSpCas9	negative selection	4612593
170564612	170564634	6	+	27760321	MV411	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.5749357494361467	[212,169]	[0,103]	-7	hSpCas9	negative selection	4612594
170562062	170562084	6	+	27760321	HL60	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.008693878209681982	[452,368]	[237,439]	0	hSpCas9	negative selection	4696053
170562102	170562124	6	-	27760321	HL60	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-1.1514212497755647	[435,386]	[186,112]	-8	hSpCas9	negative selection	4696054
170562191	170562213	6	-	27760321	HL60	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.2245586389987111	[963,813]	[395,855]	-3	hSpCas9	negative selection	4696055
170564592	170564614	6	-	27760321	HL60	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.2764651694578233	[74,64]	[24,21]	-8	hSpCas9	negative selection	4696056
170564612	170564634	6	+	27760321	HL60	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.069073019466244	[212,169]	[77,69]	-8	hSpCas9	negative selection	4696057
170562062	170562084	6	+	27760321	HT1080	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.7791215255148742	[368,287]	[28,127]	-3	hSpCas9	negative selection	4779516
170562102	170562124	6	-	27760321	HT1080	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	0.6751504951054229	[386,301]	[221,215]	3	hSpCas9	negative selection	4779517
170562191	170562213	6	-	27760321	HT1080	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.8931662102718307	[813,634]	[89,226]	-4	hSpCas9	negative selection	4779518
170564592	170564614	6	-	27760321	HT1080	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-4.530637787261012	[64,50]	[0,0]	-8	hSpCas9	negative selection	4779519
170564612	170564634	6	+	27760321	HT1080	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-5.915572858063481	[169,132]	[0,0]	-9	hSpCas9	negative selection	4779520
170562062	170562084	6	+	27760321	HT29	viability after 7 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.06518657433705621	[368,287]	[422,415,481]	1	hSpCas9	negative selection	4862979
170562102	170562124	6	-	27760321	HT29	viability after 7 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.42079873254655686	[386,301]	[325,288,374]	-6	hSpCas9	negative selection	4862980
170562191	170562213	6	-	27760321	HT29	viability after 7 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.2775055146560881	[813,634]	[994,616,725]	-4	hSpCas9	negative selection	4862981
170564592	170564614	6	-	27760321	HT29	viability after 7 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.2445029289682856	[64,50]	[7,17,63]	-9	hSpCas9	negative selection	4862982
170564612	170564634	6	+	27760321	HT29	viability after 7 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.3960684255443816	[169,132]	[266,144,51]	-5	hSpCas9	negative selection	4862983
170562062	170562084	6	+	27760321	HT29	viability after 25 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.017642701249310208	[368,287]	[386,415,330]	0	hSpCas9	negative selection	4946442
170562102	170562124	6	-	27760321	HT29	viability after 25 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-2.6554750739508353	[386,301]	[91,43,47]	-8	hSpCas9	negative selection	4946443
170562191	170562213	6	-	27760321	HT29	viability after 25 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.8752746210059802	[813,634]	[279,418,689]	-6	hSpCas9	negative selection	4946444
170564592	170564614	6	-	27760321	HT29	viability after 25 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-6.050320052107536	[64,50]	[0,0,0]	-9	hSpCas9	negative selection	4946445
170564612	170564634	6	+	27760321	HT29	viability after 25 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.6840276040636826	[169,132]	[44,21,10]	-8	hSpCas9	negative selection	4946446
170562062	170562084	6	+	27760321	HT29	viability after 22 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.12141228637666035	[368,287]	[409,351,477]	1	hSpCas9	negative selection	5029905
170562102	170562124	6	-	27760321	HT29	viability after 22 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-1.8800694113552068	[386,301]	[131,76,114]	-8	hSpCas9	negative selection	5029906
170562191	170562213	6	-	27760321	HT29	viability after 22 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.6983985276795461	[813,634]	[503,393,651]	-5	hSpCas9	negative selection	5029907
170564592	170564614	6	-	27760321	HT29	viability after 22 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-5.334032958396109	[64,50]	[0,2,0]	-9	hSpCas9	negative selection	5029908
170564612	170564634	6	+	27760321	HT29	viability after 22 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-3.2298150327176187	[169,132]	[12,41,0]	-8	hSpCas9	negative selection	5029909
170562062	170562084	6	+	27760321	HT29	viability after 19 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.6576971851898165	[368,287]	[298,272,151]	-5	hSpCas9	negative selection	5113368
170562102	170562124	6	-	27760321	HT29	viability after 19 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-3.139621102434068	[386,301]	[72,17,45]	-8	hSpCas9	negative selection	5113369
170562191	170562213	6	-	27760321	HT29	viability after 19 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.7221573564664101	[813,634]	[397,767,335]	-5	hSpCas9	negative selection	5113370
170564592	170564614	6	-	27760321	HT29	viability after 19 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-6.0517986315435826	[64,50]	[0,0,0]	-9	hSpCas9	negative selection	5113371
170564612	170564634	6	+	27760321	HT29	viability after 19 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.054544788413708	[169,132]	[105,14,11]	-8	hSpCas9	negative selection	5113372
170562062	170562084	6	+	27760321	HT29	viability after 16 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.15185372115547852	[368,287]	[392,463,364]	1	hSpCas9	negative selection	5196831
170562102	170562124	6	-	27760321	HT29	viability after 16 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-2.275949219152387	[386,301]	[134,39,69]	-8	hSpCas9	negative selection	5196832
170562191	170562213	6	-	27760321	HT29	viability after 16 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.8222179996261104	[813,634]	[339,343,682]	-6	hSpCas9	negative selection	5196833
170564592	170564614	6	-	27760321	HT29	viability after 16 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-5.631999422955984	[64,50]	[1,0,0]	-9	hSpCas9	negative selection	5196834
170564612	170564634	6	+	27760321	HT29	viability after 16 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-4.618468537307621	[169,132]	[18,0,1]	-9	hSpCas9	negative selection	5196835
170562062	170562084	6	+	27760321	HT29	viability after 13 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.11212802750478063	[368,287]	[590,194,446]	1	hSpCas9	negative selection	5280294
170562102	170562124	6	-	27760321	HT29	viability after 13 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-2.1386210662697858	[386,301]	[89,86,94]	-8	hSpCas9	negative selection	5280295
170562191	170562213	6	-	27760321	HT29	viability after 13 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.0744731802407574	[813,634]	[176,506,506]	-7	hSpCas9	negative selection	5280296
170564592	170564614	6	-	27760321	HT29	viability after 13 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.3046020063406254	[64,50]	[1,72,7]	-8	hSpCas9	negative selection	5280297
170564612	170564634	6	+	27760321	HT29	viability after 13 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.3591642563913298	[169,132]	[129,16,58]	-8	hSpCas9	negative selection	5280298
170562062	170562084	6	+	27760321	HT29	viability after 10 days	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-1.1874331766646107	[368,287]	[229,192,118]	-8	hSpCas9	negative selection	5363757
170562102	170562124	6	-	27760321	HT29	viability after 10 days	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.9163926943990509	[386,301]	[90,155,429]	-7	hSpCas9	negative selection	5363758
170562191	170562213	6	-	27760321	HT29	viability after 10 days	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.9260499508667401	[813,634]	[309,487,626]	-7	hSpCas9	negative selection	5363759
170564592	170564614	6	-	27760321	HT29	viability after 10 days	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-3.3698008123119756	[64,50]	[14,2,2]	-9	hSpCas9	negative selection	5363760
170564612	170564634	6	+	27760321	HT29	viability after 10 days	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.3670240387148302	[169,132]	[79,109,31]	-8	hSpCas9	negative selection	5363761
170562062	170562084	6	+	27760321	MOLM13	viability	AGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.5521220142129541	[452,368]	[219,103]	-4	hSpCas9	negative selection	5447220
170562102	170562124	6	-	27760321	MOLM13	viability	AGTTGTGAGAGTCTGTGAGTGG	TBP	ENSG00000112592	-0.9020815354988796	[435,386]	[136,112]	-5	hSpCas9	negative selection	5447221
170562191	170562213	6	-	27760321	MOLM13	viability	GAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.15967314887810813	[963,813]	[569,342]	-1	hSpCas9	negative selection	5447222
170564592	170564614	6	-	27760321	MOLM13	viability	TTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-2.6213876529905087	[74,64]	[0,10]	-8	hSpCas9	negative selection	5447223
170564612	170564634	6	+	27760321	MOLM13	viability	AACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-3.648891849701516	[212,169]	[0,14]	-9	hSpCas9	negative selection	5447224
170554312	170554335	6	+	27661255	K562	viability	GCTGAAGCCGAGGGCAGAACTGG	TBP	ENSG00000112592	0.4467694442706227	[318,380]	[408,354]	9	dCas9-KRAB	negative selection	5516218
170554372	170554395	6	+	27661255	K562	viability	GAGGTCGGGCAGGTTCGCTGTGG	TBP	ENSG00000112592	-0.8724480840505264	[723,631]	[349,250]	-8	dCas9-KRAB	negative selection	5516219
170554437	170554460	6	-	27661255	K562	viability	GTCACTGCAAAGATCACTATGGG	TBP	ENSG00000112592	-0.17682899122148812	[775,691]	[610,441]	-5	dCas9-KRAB	negative selection	5516220
170554587	170554610	6	-	27661255	K562	viability	GGAACGGCGGCAGCACGAAAGGG	TBP	ENSG00000112592	-0.44978234817833623	[1063,1137]	[708,586]	-7	dCas9-KRAB	negative selection	5516221
170554600	170554623	6	-	27661255	K562	viability	GCCGTTACAGGCCGGAACGGCGG	TBP	ENSG00000112592	-0.18064120930585592	[342,461]	[333,237]	-5	dCas9-KRAB	negative selection	5516222
170554764	170554787	6	-	27661255	K562	viability	GGACAGGGCAGGGTAAACTTAGG	TBP	ENSG00000112592	0.11443221361689793	[1131,1294]	[1170,940]	4	dCas9-KRAB	negative selection	5516223
170564592	170564615	6	-	27260156	BXPC3	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.5872191836244057	[293]	[148,224,256,189]	-8	hSpCas9	negative selection	5574704
170566908	170566931	6	+	27260156	BXPC3	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.9469248143660174	[765]	[386,435,338,508]	-9	hSpCas9	negative selection	5574705
170562042	170562065	6	+	27260156	BXPC3	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.16695566622621485	[438]	[475,523,438,635]	3	hSpCas9	negative selection	5574706
170564611	170564634	6	+	27260156	BXPC3	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.7630742905448942	[222]	[113,141,167,125]	-9	hSpCas9	negative selection	5638958
170566958	170566981	6	-	27260156	BXPC3	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.7299847311045287	[230]	[178,69,155,181]	-9	hSpCas9	negative selection	5638959
170569733	170569756	6	-	27260156	BXPC3	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.4782458724619616	[120]	[136,192,171,208]	8	hSpCas9	negative selection	5638960
170564592	170564615	6	-	27260156	A673	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.3823036103357883	[293]	[307,330,181,264]	-7	hSpCas9	negative selection	5695955
170566908	170566931	6	+	27260156	A673	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.5201917545450038	[765]	[746,546,696,583]	-8	hSpCas9	negative selection	5695956
170562042	170562065	6	+	27260156	A673	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.10294377189424982	[438]	[533,584,414,427]	-3	hSpCas9	negative selection	5695957
170564611	170564634	6	+	27260156	A673	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.737265280988394	[222]	[136,169,172,158]	-9	hSpCas9	negative selection	5760209
170566958	170566981	6	-	27260156	A673	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.7702115154133693	[230]	[117,129,135,267]	-9	hSpCas9	negative selection	5760210
170569733	170569756	6	-	27260156	A673	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.5779968971975744	[120]	[103,84,105,94]	-8	hSpCas9	negative selection	5760211
170564592	170564615	6	-	27260156	A375	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.1089673651805794	[293]	[138,134,146,205]	-8	hSpCas9	negative selection	5817206
170566908	170566931	6	+	27260156	A375	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.1005493078671515	[765]	[517,332,486,328]	-8	hSpCas9	negative selection	5817207
170562042	170562065	6	+	27260156	A375	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.16327441818433325	[438]	[415,447,440,515]	-2	hSpCas9	negative selection	5817208
170564611	170564634	6	+	27260156	A375	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.5825862279366825	[222]	[72,134,85,62]	-9	hSpCas9	negative selection	5881460
170566958	170566981	6	-	27260156	A375	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-2.0464458458973636	[230]	[13,107,110,36]	-9	hSpCas9	negative selection	5881461
170569733	170569756	6	-	27260156	A375	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.7925038469790266	[120]	[259,393,302,63]	9	hSpCas9	negative selection	5881462
170564592	170564615	6	-	27260156	COLO741	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7257883344192194	[293]	[368,198,131]	-9	hSpCas9	negative selection	5938457
170566908	170566931	6	+	27260156	COLO741	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8423016685402371	[765]	[546,605,487]	-9	hSpCas9	negative selection	5938458
170562042	170562065	6	+	27260156	COLO741	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.18048757687447192	[438]	[426,637,418]	-4	hSpCas9	negative selection	5938459
170564611	170564634	6	+	27260156	COLO741	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.292416192843385	[222]	[110,130,106]	-9	hSpCas9	negative selection	6002711
170566958	170566981	6	-	27260156	COLO741	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.797916876441632	[230]	[140,257,111]	-9	hSpCas9	negative selection	6002712
170569733	170569756	6	-	27260156	COLO741	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.18654259292813635	[120]	[218,163,149]	4	hSpCas9	negative selection	6002713
170564592	170564615	6	-	27260156	CAL120	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.3203601689978305	[293]	[430,195,272]	-5	hSpCas9	negative selection	6059708
170566908	170566931	6	+	27260156	CAL120	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.5976662881287407	[765]	[327,209,406]	-9	hSpCas9	negative selection	6059709
170562042	170562065	6	+	27260156	CAL120	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.17430692495318897	[438]	[910,567,417]	2	hSpCas9	negative selection	6059710
170564611	170564634	6	+	27260156	CAL120	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.5726423196258739	[222]	[81,94,100]	-9	hSpCas9	negative selection	6123962
170566958	170566981	6	-	27260156	CAL120	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.8674287567347656	[230]	[197,139,140]	-8	hSpCas9	negative selection	6123963
170569733	170569756	6	-	27260156	CAL120	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.6794102710157595	[120]	[334,192,209]	8	hSpCas9	negative selection	6123964
170564592	170564615	6	-	27260156	CADOES1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.3074178292683891	[293]	[187,312,190,190]	-5	hSpCas9	negative selection	6180959
170566908	170566931	6	+	27260156	CADOES1	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8928554356884306	[765]	[368,339,457,366]	-9	hSpCas9	negative selection	6180960
170562042	170562065	6	+	27260156	CADOES1	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.26404739003815014	[438]	[348,344,351,312]	-4	hSpCas9	negative selection	6180961
170564611	170564634	6	+	27260156	CADOES1	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.9670025567832985	[222]	[122,138,92,67]	-9	hSpCas9	negative selection	6245213
170566958	170566981	6	-	27260156	CADOES1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.9027826812455775	[230]	[156,99,125,74]	-9	hSpCas9	negative selection	6245214
170569733	170569756	6	-	27260156	CADOES1	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.14946889717723688	[120]	[96,105,97,104]	-3	hSpCas9	negative selection	6245215
170564592	170564615	6	-	27260156	EWS502	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.9236288427483758	[293]	[235,167,124,113]	-8	hSpCas9	negative selection	6302210
170566908	170566931	6	+	27260156	EWS502	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.12972268492195	[765]	[438,335,283,417]	-9	hSpCas9	negative selection	6302211
170562042	170562065	6	+	27260156	EWS502	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.2412657651772056	[438]	[411,435,309,409]	-4	hSpCas9	negative selection	6302212
170564611	170564634	6	+	27260156	EWS502	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.556562196043941	[222]	[49,33,9,66]	-9	hSpCas9	negative selection	6366464
170566958	170566981	6	-	27260156	EWS502	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.4914657165165979	[230]	[42,89,94,127]	-9	hSpCas9	negative selection	6366465
170569733	170569756	6	-	27260156	EWS502	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.24664828199128852	[120]	[125,165,124,195]	4	hSpCas9	negative selection	6366466
170564592	170564615	6	-	27260156	EW8	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.390266221538662	[293]	[185,85,225,220]	-6	hSpCas9	negative selection	6423461
170566908	170566931	6	+	27260156	EW8	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8449049516564235	[765]	[340,426,294,326]	-9	hSpCas9	negative selection	6423462
170562042	170562065	6	+	27260156	EW8	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.42557391155801416	[438]	[504,498,364,562]	7	hSpCas9	negative selection	6423463
170564611	170564634	6	+	27260156	EW8	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.0504740449471384	[222]	[148,72,72,62]	-9	hSpCas9	negative selection	6487715
170566958	170566981	6	-	27260156	EW8	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.0861780340518536	[230]	[30,128,71,116]	-9	hSpCas9	negative selection	6487716
170569733	170569756	6	-	27260156	EW8	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.7703228047490187	[120]	[118,257,123,169]	9	hSpCas9	negative selection	6487717
170564592	170564615	6	-	27260156	CORL105	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6058300194121847	[293]	[195,236,255,218]	-8	hSpCas9	negative selection	6544712
170566908	170566931	6	+	27260156	CORL105	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.6597130399741454	[765]	[476,720,576,490]	-8	hSpCas9	negative selection	6544713
170562042	170562065	6	+	27260156	CORL105	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.012402843525517362	[438]	[545,450,532,513]	0	hSpCas9	negative selection	6544714
170564611	170564634	6	+	27260156	CORL105	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.9764930665163654	[222]	[207,137,110,72]	-9	hSpCas9	negative selection	6608966
170566958	170566981	6	-	27260156	CORL105	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.909910568258224	[230]	[92,155,96,219]	-9	hSpCas9	negative selection	6608967
170569733	170569756	6	-	27260156	CORL105	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.14245008780513024	[120]	[220,130,116,45]	-3	hSpCas9	negative selection	6608968
170564592	170564615	6	-	27260156	HS294T	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4612285311646539	[293]	[82,39,107,103]	-6	hSpCas9	negative selection	6665963
170566908	170566931	6	+	27260156	HS294T	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8340754944335356	[765]	[160,140,173,193]	-8	hSpCas9	negative selection	6665964
170562042	170562065	6	+	27260156	HS294T	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.2878731639234766	[438]	[214,131,165,338]	4	hSpCas9	negative selection	6665965
170564611	170564634	6	+	27260156	HS294T	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.8818450786639296	[222]	[31,26,38,99]	-8	hSpCas9	negative selection	6730217
170566958	170566981	6	-	27260156	HS294T	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.9239785539018122	[230]	[12,35,69,77]	-8	hSpCas9	negative selection	6730218
170569733	170569756	6	-	27260156	HS294T	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.5090053862922694	[120]	[34,58,50,135]	6	hSpCas9	negative selection	6730219
170564592	170564615	6	-	27260156	HCC44	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7233276757906645	[293]	[125,276,216,169]	-8	hSpCas9	negative selection	6787214
170566908	170566931	6	+	27260156	HCC44	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.2034433041390749	[765]	[313,234,610,395]	-9	hSpCas9	negative selection	6787215
170562042	170562065	6	+	27260156	HCC44	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.1895623829112728	[438]	[532,314,512,416]	-3	hSpCas9	negative selection	6787216
170564611	170564634	6	+	27260156	HCC44	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.418248717832698	[222]	[38,28,135,2]	-9	hSpCas9	negative selection	6851468
170566958	170566981	6	-	27260156	HCC44	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-2.546425867629377	[230]	[24,55,59,36]	-9	hSpCas9	negative selection	6851469
170569733	170569756	6	-	27260156	HCC44	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.48537118504736854	[120]	[147,276,163,155]	7	hSpCas9	negative selection	6851470
170564592	170564615	6	-	27260156	G402	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4488834679932786	[293]	[109,257,250,401]	-5	hSpCas9	negative selection	6908465
170566908	170566931	6	+	27260156	G402	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.6603807821624579	[765]	[347,339,255,249]	-9	hSpCas9	negative selection	6908466
170562042	170562065	6	+	27260156	G402	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.6931148366819913	[438]	[352,508,176,299]	-7	hSpCas9	negative selection	6908467
170564611	170564634	6	+	27260156	G402	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.1553269360794918	[222]	[0,184,45,12]	-9	hSpCas9	negative selection	6972719
170566958	170566981	6	-	27260156	G402	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.8936523919580786	[230]	[40,53,197,284]	-8	hSpCas9	negative selection	6972720
170569733	170569756	6	-	27260156	G402	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.5729070689268894	[120]	[153,171,268,267]	7	hSpCas9	negative selection	6972721
170564592	170564615	6	-	27260156	L33	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	0.2737932818395274	[293]	[283,142,243,401]	6	hSpCas9	negative selection	7029716
170566908	170566931	6	+	27260156	L33	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.4262055863837454	[765]	[551,273,366,476]	-7	hSpCas9	negative selection	7029717
170562042	170562065	6	+	27260156	L33	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.03323013234457042	[438]	[444,182,268,476]	0	hSpCas9	negative selection	7029718
170564611	170564634	6	+	27260156	L33	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.1555179755739411	[222]	[175,66,123,263]	-4	hSpCas9	negative selection	7093970
170566958	170566981	6	-	27260156	L33	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.3379939517844355	[230]	[168,71,106,215]	-7	hSpCas9	negative selection	7093971
170569733	170569756	6	-	27260156	L33	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.008290893975628544	[120]	[135,35,67,153]	0	hSpCas9	negative selection	7093972
170564592	170564615	6	-	27260156	K562	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.8315779933617886	[293]	[129,53,71,43]	-9	hSpCas9	negative selection	7150967
170566908	170566931	6	+	27260156	K562	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.304280161865928	[765]	[360,196,252,289]	-8	hSpCas9	negative selection	7150968
170562042	170562065	6	+	27260156	K562	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.02456391616912519	[438]	[220,560,441,310]	0	hSpCas9	negative selection	7150969
170564611	170564634	6	+	27260156	K562	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.2873078464203984	[222]	[47,182,102,1]	-8	hSpCas9	negative selection	7215221
170566958	170566981	6	-	27260156	K562	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.9389608110387098	[230]	[65,101,40,12]	-9	hSpCas9	negative selection	7215222
170569733	170569756	6	-	27260156	K562	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.0879752445945754	[120]	[132,170,121,42]	1	hSpCas9	negative selection	7215223
170564592	170564615	6	-	27260156	HT29	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.246643763036682	[293]	[150,88,87,254]	-9	hSpCas9	negative selection	7272218
170566908	170566931	6	+	27260156	HT29	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.6540805881915799	[765]	[354,212,379,237]	-9	hSpCas9	negative selection	7272219
170562042	170562065	6	+	27260156	HT29	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.04287460245737203	[438]	[535,655,563,346]	-1	hSpCas9	negative selection	7272220
170564611	170564634	6	+	27260156	HT29	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.8689820744830743	[222]	[103,92,62,43]	-9	hSpCas9	negative selection	7336472
170566958	170566981	6	-	27260156	HT29	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-2.303509545792451	[230]	[61,37,69,55]	-9	hSpCas9	negative selection	7336473
170569733	170569756	6	-	27260156	HT29	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.07767381946040164	[120]	[118,180,224,100]	1	hSpCas9	negative selection	7336474
170564592	170564615	6	-	27260156	MHHES1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.23584135262859673	[293]	[267,337,345,191]	-4	hSpCas9	negative selection	7393469
170566908	170566931	6	+	27260156	MHHES1	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.4191408102229164	[765]	[977,750,421,498]	-7	hSpCas9	negative selection	7393470
170562042	170562065	6	+	27260156	MHHES1	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.06317267604761811	[438]	[690,479,571,364]	1	hSpCas9	negative selection	7393471
170564611	170564634	6	+	27260156	MHHES1	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.1564147632490132	[222]	[180,71,65,128]	-9	hSpCas9	negative selection	7457723
170566958	170566981	6	-	27260156	MHHES1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.1311714627454266	[230]	[63,52,199,137]	-9	hSpCas9	negative selection	7457724
170569733	170569756	6	-	27260156	MHHES1	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.48683441304922703	[120]	[83,95,147,64]	-7	hSpCas9	negative selection	7457725
170564592	170564615	6	-	27260156	MEWO	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4636850556406241	[293]	[233,199,170]	-7	hSpCas9	negative selection	7514720
170566908	170566931	6	+	27260156	MEWO	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8513709308218489	[765]	[393,376,419]	-9	hSpCas9	negative selection	7514721
170562042	170562065	6	+	27260156	MEWO	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.023555989370656255	[438]	[456,413,388]	0	hSpCas9	negative selection	7514722
170564611	170564634	6	+	27260156	MEWO	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.162309811242277	[222]	[109,67,104]	-9	hSpCas9	negative selection	7578974
170566958	170566981	6	-	27260156	MEWO	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.036297189531902	[230]	[58,127,119]	-9	hSpCas9	negative selection	7578975
170569733	170569756	6	-	27260156	MEWO	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.12022017982031863	[120]	[85,86,135]	-3	hSpCas9	negative selection	7578976
170564592	170564615	6	-	27260156	LNCAPCLONEFGC	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.14237697672931293	[293]	[255,230,278,204]	-2	hSpCas9	negative selection	7635971
170566908	170566931	6	+	27260156	LNCAPCLONEFGC	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.0694601289419894	[765]	[240,387,247,430]	-9	hSpCas9	negative selection	7635972
170562042	170562065	6	+	27260156	LNCAPCLONEFGC	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.04979059611393795	[438]	[346,421,446,327]	-1	hSpCas9	negative selection	7635973
170564611	170564634	6	+	27260156	LNCAPCLONEFGC	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.4433595080565405	[222]	[52,85,82,75]	-9	hSpCas9	negative selection	7700225
170566958	170566981	6	-	27260156	LNCAPCLONEFGC	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.46169450680148	[230]	[87,83,61,66]	-9	hSpCas9	negative selection	7700226
170569733	170569756	6	-	27260156	LNCAPCLONEFGC	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.5877163768576867	[120]	[174,198,175,107]	8	hSpCas9	negative selection	7700227
170564592	170564615	6	-	27260156	PANC0327	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.7030310407085	[293]	[183,178,65,211]	-7	hSpCas9	negative selection	7757222
170566908	170566931	6	+	27260156	PANC0327	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.1392810942233327	[765]	[401,341,309,184]	-8	hSpCas9	negative selection	7757223
170562042	170562065	6	+	27260156	PANC0327	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.3727746513855807	[438]	[456,663,396,476]	5	hSpCas9	negative selection	7757224
170564611	170564634	6	+	27260156	PANC0327	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.8259042945219188	[222]	[13,125,45,24]	-9	hSpCas9	negative selection	7821476
170566958	170566981	6	-	27260156	PANC0327	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.9243516158639302	[230]	[22,105,54,22]	-9	hSpCas9	negative selection	7821477
170569733	170569756	6	-	27260156	PANC0327	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.10132504778372886	[120]	[108,88,96,168]	1	hSpCas9	negative selection	7821478
170564592	170564615	6	-	27260156	NCIH2009	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.1013807376321063	[293]	[215,238,122]	-8	hSpCas9	negative selection	7878473
170566908	170566931	6	+	27260156	NCIH2009	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.224950808336412	[765]	[417,617,325]	-8	hSpCas9	negative selection	7878474
170562042	170562065	6	+	27260156	NCIH2009	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.4052243922605307	[438]	[959,679,826]	5	hSpCas9	negative selection	7878475
170564611	170564634	6	+	27260156	NCIH2009	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.8159318000688036	[222]	[71,91,97]	-9	hSpCas9	negative selection	7942727
170566958	170566981	6	-	27260156	NCIH2009	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-2.1203085752954354	[230]	[110,64,53]	-9	hSpCas9	negative selection	7942728
170569733	170569756	6	-	27260156	NCIH2009	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.33246022397863917	[120]	[156,136,112]	-4	hSpCas9	negative selection	7942729
170564592	170564615	6	-	27260156	NCIH1373	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.9329756268575603	[293]	[238,46,194,61]	-7	hSpCas9	negative selection	7999724
170566908	170566931	6	+	27260156	NCIH1373	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.003938394897328	[765]	[366,737,263,76]	-7	hSpCas9	negative selection	7999725
170562042	170562065	6	+	27260156	NCIH1373	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.5775451305988096	[438]	[946,795,483,193]	6	hSpCas9	negative selection	7999726
170564611	170564634	6	+	27260156	NCIH1373	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.1005938440242784	[222]	[354,43,389,45]	-1	hSpCas9	negative selection	8063978
170566958	170566981	6	-	27260156	NCIH1373	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.5954034088860247	[230]	[86,179,42,4]	-9	hSpCas9	negative selection	8063979
170569733	170569756	6	-	27260156	NCIH1373	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.2839809377695153	[120]	[113,174,43,27]	-3	hSpCas9	negative selection	8063980
170564592	170564615	6	-	27260156	PATU8902	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.711746031461964	[293]	[220,319,244,208]	-6	hSpCas9	negative selection	8120975
170566908	170566931	6	+	27260156	PATU8902	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.3555308492715947	[765]	[362,539,364,409]	-8	hSpCas9	negative selection	8120976
170562042	170562065	6	+	27260156	PATU8902	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.6211300305869054	[438]	[1009,1287,597,947]	6	hSpCas9	negative selection	8120977
170564611	170564634	6	+	27260156	PATU8902	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.88241819202515	[222]	[3,3,71,85]	-9	hSpCas9	negative selection	8185229
170566958	170566981	6	-	27260156	PATU8902	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-4.416018258329043	[230]	[4,27,7,21]	-9	hSpCas9	negative selection	8185230
170569733	170569756	6	-	27260156	PATU8902	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.08362888149497572	[120]	[290,166,83,195]	0	hSpCas9	negative selection	8185231
170564592	170564615	6	-	27260156	PANC1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-2.03445747081491	[293]	[37,118,47,53]	-9	hSpCas9	negative selection	8242226
170566908	170566931	6	+	27260156	PANC1	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.1706659711924818	[765]	[302,452,241,211]	-9	hSpCas9	negative selection	8242227
170562042	170562065	6	+	27260156	PANC1	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.007409342440859043	[438]	[359,620,322,259]	0	hSpCas9	negative selection	8242228
170564611	170564634	6	+	27260156	PANC1	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.039572811887033	[222]	[25,96,11,58]	-9	hSpCas9	negative selection	8306480
170566958	170566981	6	-	27260156	PANC1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.8290846301119479	[230]	[25,118,15,71]	-9	hSpCas9	negative selection	8306481
170569733	170569756	6	-	27260156	PANC1	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	-0.09287046890540585	[120]	[177,57,71,73]	-1	hSpCas9	negative selection	8306482
170564592	170564615	6	-	27260156	PANC0813	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6276140741063657	[293]	[229,193,324,149]	-7	hSpCas9	negative selection	8363477
170566908	170566931	6	+	27260156	PANC0813	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.357887873519739	[765]	[549,390,301,187]	-9	hSpCas9	negative selection	8363478
170562042	170562065	6	+	27260156	PANC0813	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.316307929345072	[438]	[798,517,712,556]	5	hSpCas9	negative selection	8363479
170564611	170564634	6	+	27260156	PANC0813	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.8471609667397082	[222]	[103,92,204,174]	-8	hSpCas9	negative selection	8427731
170566958	170566981	6	-	27260156	PANC0813	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.7140000062775385	[230]	[78,112,51,85]	-9	hSpCas9	negative selection	8427732
170569733	170569756	6	-	27260156	PANC0813	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.32307220403072745	[120]	[163,306,145,96]	5	hSpCas9	negative selection	8427733
170564592	170564615	6	-	27260156	RDES	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4636220226673987	[293]	[248,222,153,361]	-7	hSpCas9	negative selection	8484728
170566908	170566931	6	+	27260156	RDES	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.1620177409108685	[765]	[309,405,476,388]	-9	hSpCas9	negative selection	8484729
170562042	170562065	6	+	27260156	RDES	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.201156131072697	[438]	[432,587,649,682]	3	hSpCas9	negative selection	8484730
170564611	170564634	6	+	27260156	RDES	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.0598512402603864	[222]	[70,109,188,135]	-9	hSpCas9	negative selection	8548982
170566958	170566981	6	-	27260156	RDES	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.2716533856788281	[230]	[101,105,142,84]	-9	hSpCas9	negative selection	8548983
170569733	170569756	6	-	27260156	RDES	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.375156002478118	[120]	[127,235,186,169]	6	hSpCas9	negative selection	8548984
170564592	170564615	6	-	27260156	PC3	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.06593784699606053	[293]	[151,287,469,316]	-1	hSpCas9	negative selection	8605979
170566908	170566931	6	+	27260156	PC3	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.5766095155069253	[765]	[374,387,659,700]	-8	hSpCas9	negative selection	8605980
170562042	170562065	6	+	27260156	PC3	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.2196300656810769	[438]	[263,384,602,345]	-5	hSpCas9	negative selection	8605981
170564611	170564634	6	+	27260156	PC3	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.344938165922842	[222]	[83,53,127,90]	-9	hSpCas9	negative selection	8670233
170566958	170566981	6	-	27260156	PC3	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.3303314114774967	[230]	[103,183,229,253]	-6	hSpCas9	negative selection	8670234
170569733	170569756	6	-	27260156	PC3	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.32988813506676107	[120]	[93,119,273,179]	7	hSpCas9	negative selection	8670235
170564592	170564615	6	-	27260156	PATU8988T	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.3205328440782362	[293]	[59,99,166,126]	-9	hSpCas9	negative selection	8727230
170566908	170566931	6	+	27260156	PATU8988T	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.1716137175098624	[765]	[482,326,267,228]	-9	hSpCas9	negative selection	8727231
170562042	170562065	6	+	27260156	PATU8988T	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.4779246633960949	[438]	[348,366,248,255]	-7	hSpCas9	negative selection	8727232
170564611	170564634	6	+	27260156	PATU8988T	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-2.280456349965745	[222]	[4,39,90,39]	-9	hSpCas9	negative selection	8791484
170566958	170566981	6	-	27260156	PATU8988T	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.1416269737282447	[230]	[92,54,68,190]	-9	hSpCas9	negative selection	8791485
170569733	170569756	6	-	27260156	PATU8988T	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.19899864383861332	[120]	[54,103,185,192]	3	hSpCas9	negative selection	8791486
170564592	170564615	6	-	27260156	T47D	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.20033123157401778	[293]	[302,224,361,307]	-4	hSpCas9	negative selection	8848481
170566908	170566931	6	+	27260156	T47D	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.9282711042819195	[765]	[493,392,411,587]	-9	hSpCas9	negative selection	8848482
170562042	170562065	6	+	27260156	T47D	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.11571981153173526	[438]	[549,338,471,540]	-3	hSpCas9	negative selection	8848483
170564611	170564634	6	+	27260156	T47D	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-1.315506430041649	[222]	[98,111,77,128]	-9	hSpCas9	negative selection	8912735
170566958	170566981	6	-	27260156	T47D	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.6850994387061458	[230]	[191,229,86,155]	-8	hSpCas9	negative selection	8912736
170569733	170569756	6	-	27260156	T47D	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.33929559533374243	[120]	[131,151,215,215]	7	hSpCas9	negative selection	8912737
170564592	170564615	6	-	27260156	SU8686	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6011753102277811	[293]	[147,103,243,307]	-7	hSpCas9	negative selection	8969732
170566908	170566931	6	+	27260156	SU8686	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-1.0500822113817745	[765]	[363,277,389,459]	-8	hSpCas9	negative selection	8969733
170562042	170562065	6	+	27260156	SU8686	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	0.22060100467603977	[438]	[674,453,432,436]	4	hSpCas9	negative selection	8969734
170564611	170564634	6	+	27260156	SU8686	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.968587487785161	[222]	[89,121,83,163]	-8	hSpCas9	negative selection	9033986
170566958	170566981	6	-	27260156	SU8686	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.8871010763449747	[230]	[18,120,71,26]	-9	hSpCas9	negative selection	9033987
170569733	170569756	6	-	27260156	SU8686	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.6559206006063198	[120]	[180,179,158,244]	9	hSpCas9	negative selection	9033988
170564592	170564615	6	-	27260156	SKES1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.2936255127825641	[293]	[210,282,221,239]	-6	hSpCas9	negative selection	9090983
170566908	170566931	6	+	27260156	SKES1	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.6033057248009103	[765]	[667,553,415,409]	-8	hSpCas9	negative selection	9090984
170562042	170562065	6	+	27260156	SKES1	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.29786628337450993	[438]	[412,536,307,210]	-6	hSpCas9	negative selection	9090985
170564611	170564634	6	+	27260156	SKES1	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.5217382346805628	[222]	[134,203,141,141]	-8	hSpCas9	negative selection	9155237
170566958	170566981	6	-	27260156	SKES1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.6613864711139803	[230]	[172,162,140,113]	-8	hSpCas9	negative selection	9155238
170569733	170569756	6	-	27260156	SKES1	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.12343729891110233	[120]	[113,228,103,91]	2	hSpCas9	negative selection	9155239
170564592	170564615	6	-	27260156	TOV112D	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.5381157148366634	[293]	[285,298,144,113]	-8	hSpCas9	negative selection	9212234
170566908	170566931	6	+	27260156	TOV112D	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.6720152488816651	[765]	[572,711,488,222]	-8	hSpCas9	negative selection	9212235
170562042	170562065	6	+	27260156	TOV112D	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.42697698648370536	[438]	[367,391,273,293]	-7	hSpCas9	negative selection	9212236
170564611	170564634	6	+	27260156	TOV112D	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.6864813588531773	[222]	[69,226,141,131]	-8	hSpCas9	negative selection	9276488
170566958	170566981	6	-	27260156	TOV112D	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.6849975038519687	[230]	[89,184,235,71]	-8	hSpCas9	negative selection	9276489
170569733	170569756	6	-	27260156	TOV112D	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.4164680805500358	[120]	[150,134,255,98]	7	hSpCas9	negative selection	9276490
170564592	170564615	6	-	27260156	TC71	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.012645834062405159	[293]	[299,310,329,307]	0	hSpCas9	negative selection	9333485
170566908	170566931	6	+	27260156	TC71	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.4815580576417768	[765]	[672,573,583,514]	-8	hSpCas9	negative selection	9333486
170562042	170562065	6	+	27260156	TC71	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.01006967272286903	[438]	[513,453,495,398]	0	hSpCas9	negative selection	9333487
170564611	170564634	6	+	27260156	TC71	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.831018660784222	[222]	[159,82,129,165]	-9	hSpCas9	negative selection	9397739
170566958	170566981	6	-	27260156	TC71	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.507631889544562	[230]	[178,220,125,171]	-8	hSpCas9	negative selection	9397740
170569733	170569756	6	-	27260156	TC71	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.1422766856311488	[120]	[167,136,100,168]	3	hSpCas9	negative selection	9397741
170564592	170564615	6	-	27260156	TC32	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.09674225507428857	[293]	[239,255,305,223]	-2	hSpCas9	negative selection	9454736
170566908	170566931	6	+	27260156	TC32	viability	ACCATTGTAGCGGTTTGCTGCGG	TBP	ENSG00000112592	-0.8199054557473487	[765]	[397,208,574,539]	-9	hSpCas9	negative selection	9454737
170562042	170562065	6	+	27260156	TC32	viability	TCAGCAGTCAACGTCCCAGCAGG	TBP	ENSG00000112592	-0.13842471308863225	[438]	[371,195,619,402]	-2	hSpCas9	negative selection	9454738
170564611	170564634	6	+	27260156	TC32	viability	AAACGCCGAATATAATCCCAAGG	TBP	ENSG00000112592	-0.18556911593281344	[222]	[142,210,187,177]	-3	hSpCas9	negative selection	9518990
170566958	170566981	6	-	27260156	TC32	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.7781526993574779	[230]	[133,65,187,144]	-9	hSpCas9	negative selection	9518991
170569733	170569756	6	-	27260156	TC32	viability	ACAAGGCCTTCTAACCTTATAGG	TBP	ENSG00000112592	0.29686548102397303	[120]	[146,53,210,185]	5	hSpCas9	negative selection	9518992
170557051	170557074	6	-	27869803	HPAFII	viability after 27 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.37230530859928046	[123]	[21,73,NaN]	-3	hSpCas9	negative selection	9594480
170562066	170562089	6	+	27869803	HPAFII	viability after 27 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-1.0709128143741422	[173]	[60,28,NaN]	-6	hSpCas9	negative selection	9594481
170562127	170562150	6	-	27869803	HPAFII	viability after 27 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-0.5656728313583297	[204]	[134,20,NaN]	-4	hSpCas9	negative selection	9594482
170562128	170562151	6	-	27869803	HPAFII	viability after 27 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-4.821658562243844	[532]	[16,3,NaN]	-9	hSpCas9	negative selection	9594483
170569750	170569773	6	-	27869803	HPAFII	viability after 27 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-2.907608675878626	[156]	[16,5,NaN]	-9	hSpCas9	negative selection	9594484
170557051	170557074	6	-	27869803	HPAFII	viability after 15 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.41921667171688726	[123]	[37,137,NaN]	-4	hSpCas9	negative selection	9676929
170562066	170562089	6	+	27869803	HPAFII	viability after 15 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.40211543478536393	[173]	[114,157,NaN]	-4	hSpCas9	negative selection	9676930
170562127	170562150	6	-	27869803	HPAFII	viability after 15 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-0.0732442428312603	[204]	[349,121,NaN]	-1	hSpCas9	negative selection	9676931
170562128	170562151	6	-	27869803	HPAFII	viability after 15 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-2.1267540255607367	[532]	[87,157,NaN]	-9	hSpCas9	negative selection	9676932
170569750	170569773	6	-	27869803	HPAFII	viability after 15 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-0.3609559223650469	[156]	[131,130,NaN]	-4	hSpCas9	negative selection	9676933
170557051	170557074	6	-	27869803	ASPC1	viability after 36 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.63350900162086	[276]	[20,105,55]	-6	hSpCas9	negative selection	9759378
170562066	170562089	6	+	27869803	ASPC1	viability after 36 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	0.9580280977160862	[521]	[116,108,710]	8	hSpCas9	negative selection	9759379
170562127	170562150	6	-	27869803	ASPC1	viability after 36 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-0.06547922350886351	[581]	[154,277,152]	0	hSpCas9	negative selection	9759380
170562128	170562151	6	-	27869803	ASPC1	viability after 36 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.0756641552003168	[1050]	[108,314,105]	-8	hSpCas9	negative selection	9759381
170569750	170569773	6	-	27869803	ASPC1	viability after 36 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	0.292489888896887	[410]	[341,15,183]	3	hSpCas9	negative selection	9759382
170557051	170557074	6	-	27869803	PATU8988S	viability after 35 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.7943363735601626	[269]	[227,148,NaN]	8	hSpCas9	negative selection	9841827
170562066	170562089	6	+	27869803	PATU8988S	viability after 35 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.432777863854076	[462]	[201,73,NaN]	-4	hSpCas9	negative selection	9841828
170562127	170562150	6	-	27869803	PATU8988S	viability after 35 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.5803640495476319	[701]	[113,74,NaN]	-8	hSpCas9	negative selection	9841829
170562128	170562151	6	-	27869803	PATU8988S	viability after 35 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.9783624098125474	[1051]	[117,96,NaN]	-9	hSpCas9	negative selection	9841830
170569750	170569773	6	-	27869803	PATU8988S	viability after 35 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-1.3924997175262224	[374]	[69,44,NaN]	-8	hSpCas9	negative selection	9841831
170557051	170557074	6	-	27869803	PATU8988S	viability after 31 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.7854647587969966	[269]	[229,128,NaN]	8	hSpCas9	negative selection	9924276
170562066	170562089	6	+	27869803	PATU8988S	viability after 31 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.23667970453963671	[462]	[179,126,NaN]	-3	hSpCas9	negative selection	9924277
170562127	170562150	6	-	27869803	PATU8988S	viability after 31 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-2.1616893296243878	[701]	[62,61,NaN]	-9	hSpCas9	negative selection	9924278
170562128	170562151	6	-	27869803	PATU8988S	viability after 31 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-1.7536985370974074	[1051]	[86,171,NaN]	-9	hSpCas9	negative selection	9924279
170569750	170569773	6	-	27869803	PATU8988S	viability after 31 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-0.8702426573256554	[374]	[83,78,NaN]	-7	hSpCas9	negative selection	9924280
170557051	170557074	6	-	27869803	HPAFII	viability after 35 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	0.08064284303735081	[123]	[8,130,NaN]	0	hSpCas9	negative selection	10006725
170562066	170562089	6	+	27869803	HPAFII	viability after 35 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.5720395140893194	[173]	[94,18,NaN]	-3	hSpCas9	negative selection	10006726
170562127	170562150	6	-	27869803	HPAFII	viability after 35 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.0546762781386159	[204]	[88,5,NaN]	-5	hSpCas9	negative selection	10006727
170562128	170562151	6	-	27869803	HPAFII	viability after 35 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-2.825127294009885	[532]	[70,0,NaN]	-8	hSpCas9	negative selection	10006728
170569750	170569773	6	-	27869803	HPAFII	viability after 35 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-1.5637824798814202	[156]	[32,19,NaN]	-7	hSpCas9	negative selection	10006729
170557051	170557074	6	-	27869803	HPAFII	viability after 31 days	GCCAAGCCCTGAGCGTAAGGTGG	TBP	ENSG00000112592	-0.21616898693019637	[123]	[1,122,NaN]	-1	hSpCas9	negative selection	10089174
170562066	170562089	6	+	27869803	HPAFII	viability after 31 days	AACACAGGGAACCTCAGGCCAGG	TBP	ENSG00000112592	-0.0898237320117714	[173]	[130,48,NaN]	0	hSpCas9	negative selection	10089175
170562127	170562150	6	-	27869803	HPAFII	viability after 31 days	AGTGGAGTGGTGCCCGGCAAGGG	TBP	ENSG00000112592	-1.1141111131864458	[204]	[89,12,NaN]	-6	hSpCas9	negative selection	10089176
170562128	170562151	6	-	27869803	HPAFII	viability after 31 days	CAGTGGAGTGGTGCCCGGCAAGG	TBP	ENSG00000112592	-3.0798166343944704	[532]	[54,13,NaN]	-9	hSpCas9	negative selection	10089177
170569750	170569773	6	-	27869803	HPAFII	viability after 31 days	ATTGTTGGTGGGTGAGCACAAGG	TBP	ENSG00000112592	-1.765971536191056	[156]	[34,15,NaN]	-7	hSpCas9	negative selection	10089178
170566941	170566964	6	+	28162770	P31FUJ	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-2.780289999716872	[75]	[12]	-9	hSpCas9	negative selection	10247988
170562223	170562246	6	-	28162770	P31FUJ	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.0852450160005207	[389]	[215]	-6	hSpCas9	negative selection	10247989
170562077	170562100	6	-	28162770	P31FUJ	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.8241624763336853	[225]	[149]	-6	hSpCas9	negative selection	10247990
170564592	170564615	6	-	28162770	P31FUJ	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.4044876637211283	[204]	[90]	-7	hSpCas9	negative selection	10247991
170566958	170566981	6	-	28162770	P31FUJ	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.07865889142191507	[82]	[102]	0	hSpCas9	negative selection	10247992
170561795	170561818	6	-	28162770	P31FUJ	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.3014495513639488	[537]	[512]	-3	hSpCas9	negative selection	10247993
170561812	170561835	6	-	28162770	P31FUJ	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.029139461242246423	[586]	[675]	0	hSpCas9	negative selection	10247994
170562061	170562084	6	+	28162770	P31FUJ	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.1873917447244322	[343]	[354]	-2	hSpCas9	negative selection	10247995
170562091	170562114	6	-	28162770	P31FUJ	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.49250474955042445	[345]	[288]	-4	hSpCas9	negative selection	10247996
170562191	170562214	6	-	28162770	P31FUJ	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.0267115954070312	[266]	[153]	-6	hSpCas9	negative selection	10247997
170566941	170566964	6	+	28162770	TF1	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10417354
170562223	170562246	6	-	28162770	TF1	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10417355
170562077	170562100	6	-	28162770	TF1	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10417356
170564592	170564615	6	-	28162770	TF1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10417357
170566958	170566981	6	-	28162770	TF1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10417358
170561795	170561818	6	-	28162770	TF1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10417359
170561812	170561835	6	-	28162770	TF1	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	NaN	[NaN]	[422]	1	hSpCas9	negative selection	10417360
170562061	170562084	6	+	28162770	TF1	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10417361
170562091	170562114	6	-	28162770	TF1	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10417362
170562191	170562214	6	-	28162770	TF1	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10417363
170566941	170566964	6	+	28162770	SKM1	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.3074285251922477	[27]	[4]	-9	hSpCas9	negative selection	10586720
170562223	170562246	6	-	28162770	SKM1	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.9014361655164103	[111]	[52]	-8	hSpCas9	negative selection	10586721
170562077	170562100	6	-	28162770	SKM1	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	0.38681231681390194	[60]	[140]	4	hSpCas9	negative selection	10586722
170564592	170564615	6	-	28162770	SKM1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.5589672921882114	[34]	[20]	-8	hSpCas9	negative selection	10586723
170566958	170566981	6	-	28162770	SKM1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.6109577092541005	[19]	[53]	6	hSpCas9	negative selection	10586724
170561795	170561818	6	-	28162770	SKM1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.06068624244005072	[140]	[238]	0	hSpCas9	negative selection	10586725
170561812	170561835	6	-	28162770	SKM1	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.6873631838049915	[110]	[315]	6	hSpCas9	negative selection	10586726
170562061	170562084	6	+	28162770	SKM1	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.1890591683990276	[68]	[106]	-2	hSpCas9	negative selection	10586727
170562091	170562114	6	-	28162770	SKM1	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.43042317156715076	[92]	[121]	-4	hSpCas9	negative selection	10586728
170562191	170562214	6	-	28162770	SKM1	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.0757582902677885	[61]	[51]	-7	hSpCas9	negative selection	10586729
170566941	170566964	6	+	28162770	SKM1	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.3074285251922477	[27]	[4]	-9	hSpCas9	negative selection	10756086
170562223	170562246	6	-	28162770	SKM1	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.9014361655164103	[111]	[52]	-8	hSpCas9	negative selection	10756087
170562077	170562100	6	-	28162770	SKM1	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	0.38681231681390194	[60]	[140]	4	hSpCas9	negative selection	10756088
170564592	170564615	6	-	28162770	SKM1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.5589672921882114	[34]	[20]	-8	hSpCas9	negative selection	10756089
170566958	170566981	6	-	28162770	SKM1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.6109577092541005	[19]	[53]	6	hSpCas9	negative selection	10756090
170561795	170561818	6	-	28162770	SKM1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.06068624244005072	[140]	[238]	0	hSpCas9	negative selection	10756091
170561812	170561835	6	-	28162770	SKM1	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.6873631838049915	[110]	[315]	6	hSpCas9	negative selection	10756092
170562061	170562084	6	+	28162770	SKM1	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.1890591683990276	[68]	[106]	-2	hSpCas9	negative selection	10756093
170562091	170562114	6	-	28162770	SKM1	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.43042317156715076	[92]	[121]	-4	hSpCas9	negative selection	10756094
170562191	170562214	6	-	28162770	SKM1	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.0757582902677885	[61]	[51]	-7	hSpCas9	negative selection	10756095
170566941	170566964	6	+	28162770	PL21	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.036899582811529	[131]	[6]	-9	hSpCas9	negative selection	10925452
170562223	170562246	6	-	28162770	PL21	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-2.648599228333403	[388]	[26]	-9	hSpCas9	negative selection	10925453
170562077	170562100	6	-	28162770	PL21	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	0.333722768867912	[267]	[146]	3	hSpCas9	negative selection	10925454
170564592	170564615	6	-	28162770	PL21	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.6637988359346514	[181]	[49]	-4	hSpCas9	negative selection	10925455
170566958	170566981	6	-	28162770	PL21	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.7306543311881	[71]	[51]	6	hSpCas9	negative selection	10925456
170561795	170561818	6	-	28162770	PL21	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.15451699736352298	[513]	[248]	1	hSpCas9	negative selection	10925457
170561812	170561835	6	-	28162770	PL21	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.4608205205501419	[408]	[244]	4	hSpCas9	negative selection	10925458
170562061	170562084	6	+	28162770	PL21	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.4569150298514315	[230]	[137]	4	hSpCas9	negative selection	10925459
170562091	170562114	6	-	28162770	PL21	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.23697638266969157	[231]	[118]	2	hSpCas9	negative selection	10925460
170562191	170562214	6	-	28162770	PL21	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	0.30921131363679	[190]	[102]	2	hSpCas9	negative selection	10925461
170566941	170566964	6	+	28162770	P31FUJ	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-2.780289999716872	[75]	[12]	-9	hSpCas9	negative selection	11094818
170562223	170562246	6	-	28162770	P31FUJ	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.0852450160005207	[389]	[215]	-6	hSpCas9	negative selection	11094819
170562077	170562100	6	-	28162770	P31FUJ	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.8241624763336853	[225]	[149]	-6	hSpCas9	negative selection	11094820
170564592	170564615	6	-	28162770	P31FUJ	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-1.4044876637211283	[204]	[90]	-7	hSpCas9	negative selection	11094821
170566958	170566981	6	-	28162770	P31FUJ	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.07865889142191507	[82]	[102]	0	hSpCas9	negative selection	11094822
170561795	170561818	6	-	28162770	P31FUJ	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.3014495513639488	[537]	[512]	-3	hSpCas9	negative selection	11094823
170561812	170561835	6	-	28162770	P31FUJ	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.029139461242246423	[586]	[675]	0	hSpCas9	negative selection	11094824
170562061	170562084	6	+	28162770	P31FUJ	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.1873917447244322	[343]	[354]	-2	hSpCas9	negative selection	11094825
170562091	170562114	6	-	28162770	P31FUJ	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.49250474955042445	[345]	[288]	-4	hSpCas9	negative selection	11094826
170562191	170562214	6	-	28162770	P31FUJ	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.0267115954070312	[266]	[153]	-6	hSpCas9	negative selection	11094827
170566941	170566964	6	+	28162770	OCIAML5	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.700063477418947	[71]	[9]	-9	hSpCas9	negative selection	11264184
170562223	170562246	6	-	28162770	OCIAML5	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.080972299159119	[258]	[220]	-6	hSpCas9	negative selection	11264185
170562077	170562100	6	-	28162770	OCIAML5	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-1.3104966656562214	[179]	[130]	-6	hSpCas9	negative selection	11264186
170564592	170564615	6	-	28162770	OCIAML5	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-4.137468789726245	[77]	[7]	-9	hSpCas9	negative selection	11264187
170566958	170566981	6	-	28162770	OCIAML5	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.0010920408067318643	[30]	[55]	0	hSpCas9	negative selection	11264188
170561795	170561818	6	-	28162770	OCIAML5	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.12882460618829805	[265]	[524]	1	hSpCas9	negative selection	11264189
170561812	170561835	6	-	28162770	OCIAML5	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.0519729981323267	[312]	[544]	0	hSpCas9	negative selection	11264190
170562061	170562084	6	+	28162770	OCIAML5	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.3046589328234563	[121]	[271]	2	hSpCas9	negative selection	11264191
170562091	170562114	6	-	28162770	OCIAML5	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.3969007228342466	[145]	[346]	3	hSpCas9	negative selection	11264192
170562191	170562214	6	-	28162770	OCIAML5	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.670896812254062	[141]	[160]	-4	hSpCas9	negative selection	11264193
170566941	170566964	6	+	28162770	EOL1	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-4.660414729150621	[239]	[4]	-9	hSpCas9	negative selection	11433550
170562223	170562246	6	-	28162770	EOL1	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.7320757142780678	[453]	[143]	-5	hSpCas9	negative selection	11433551
170562077	170562100	6	-	28162770	EOL1	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.32942729497579315	[507]	[212]	-2	hSpCas9	negative selection	11433552
170564592	170564615	6	-	28162770	EOL1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.8377606707101349	[267]	[78]	-5	hSpCas9	negative selection	11433553
170566958	170566981	6	-	28162770	EOL1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.4224713042796584	[144]	[56]	-3	hSpCas9	negative selection	11433554
170561795	170561818	6	-	28162770	EOL1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.6355969991294452	[864]	[707]	5	hSpCas9	negative selection	11433555
170561812	170561835	6	-	28162770	EOL1	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.033072228348703714	[511]	[275]	0	hSpCas9	negative selection	11433556
170562061	170562084	6	+	28162770	EOL1	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.1739804333354657	[408]	[190]	-1	hSpCas9	negative selection	11433557
170562091	170562114	6	-	28162770	EOL1	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.3439410643553673	[370]	[153]	-3	hSpCas9	negative selection	11433558
170562191	170562214	6	-	28162770	EOL1	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.8912522187433263	[256]	[72]	-6	hSpCas9	negative selection	11433559
170566941	170566964	6	+	28162770	MOLM13	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.874502815902499	[141]	[6]	-9	hSpCas9	negative selection	11602916
170562223	170562246	6	-	28162770	MOLM13	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.2022405024392546	[470]	[147]	-6	hSpCas9	negative selection	11602917
170562077	170562100	6	-	28162770	MOLM13	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	0.3193253720663001	[418]	[377]	2	hSpCas9	negative selection	11602918
170564592	170564615	6	-	28162770	MOLM13	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.48148454538545327	[167]	[86]	-3	hSpCas9	negative selection	11602919
170566958	170566981	6	-	28162770	MOLM13	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.28547065087229595	[117]	[69]	-2	hSpCas9	negative selection	11602920
170561795	170561818	6	-	28162770	MOLM13	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.6819338161533655	[618]	[717]	5	hSpCas9	negative selection	11602921
170561812	170561835	6	-	28162770	MOLM13	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.5259496338287472	[700]	[351]	-3	hSpCas9	negative selection	11602922
170562061	170562084	6	+	28162770	MOLM13	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.5830372541300999	[336]	[364]	4	hSpCas9	negative selection	11602923
170562091	170562114	6	-	28162770	MOLM13	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.052851882265735006	[307]	[230]	0	hSpCas9	negative selection	11602924
170562191	170562214	6	-	28162770	MOLM13	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.763436164561877	[323]	[137]	-4	hSpCas9	negative selection	11602925
170566941	170566964	6	+	28162770	HEL	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.5860798584955242	[149]	[7]	-9	hSpCas9	negative selection	11772282
170562223	170562246	6	-	28162770	HEL	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.8821026762832285	[422]	[146]	-5	hSpCas9	negative selection	11772283
170562077	170562100	6	-	28162770	HEL	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-1.4477161189451468	[361]	[84]	-7	hSpCas9	negative selection	11772284
170564592	170564615	6	-	28162770	HEL	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.9156294587090863	[214]	[72]	-5	hSpCas9	negative selection	11772285
170566958	170566981	6	-	28162770	HEL	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	0.42592744292720885	[85]	[73]	3	hSpCas9	negative selection	11772286
170561795	170561818	6	-	28162770	HEL	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.5787139200650602	[621]	[594]	5	hSpCas9	negative selection	11772287
170561812	170561835	6	-	28162770	HEL	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	0.0803500230152312	[538]	[364]	0	hSpCas9	negative selection	11772288
170562061	170562084	6	+	28162770	HEL	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.3923639981380286	[294]	[247]	3	hSpCas9	negative selection	11772289
170562091	170562114	6	-	28162770	HEL	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.8402496651145686	[258]	[296]	7	hSpCas9	negative selection	11772290
170562191	170562214	6	-	28162770	HEL	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	0.6847329206649841	[236]	[243]	6	hSpCas9	negative selection	11772291
170566941	170566964	6	+	28162770	MV411	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-6.507449951380694	[107]	[0]	-9	hSpCas9	negative selection	11941648
170562223	170562246	6	-	28162770	MV411	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.7612273103443521	[333]	[165]	-5	hSpCas9	negative selection	11941649
170562077	170562100	6	-	28162770	MV411	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	0.490891587647053	[271]	[321]	4	hSpCas9	negative selection	11941650
170564592	170564615	6	-	28162770	MV411	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.20154728041940628	[171]	[125]	-1	hSpCas9	negative selection	11941651
170566958	170566981	6	-	28162770	MV411	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-3.337524949938381	[71]	[5]	-9	hSpCas9	negative selection	11941652
170561795	170561818	6	-	28162770	MV411	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	-0.04279954492953153	[438]	[358]	0	hSpCas9	negative selection	11941653
170561812	170561835	6	-	28162770	MV411	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.09435096646542984	[383]	[302]	0	hSpCas9	negative selection	11941654
170562061	170562084	6	+	28162770	MV411	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.31503562893358583	[270]	[283]	2	hSpCas9	negative selection	11941655
170562091	170562114	6	-	28162770	MV411	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.12690388547528664	[261]	[240]	1	hSpCas9	negative selection	11941656
170562191	170562214	6	-	28162770	MV411	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.5122034813513278	[170]	[100]	-4	hSpCas9	negative selection	11941657
170566941	170566964	6	+	28162770	MONOMAC1	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-3.1418952928670922	[76]	[9]	-9	hSpCas9	negative selection	12111014
170562223	170562246	6	-	28162770	MONOMAC1	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.9631120298554807	[266]	[156]	-6	hSpCas9	negative selection	12111015
170562077	170562100	6	-	28162770	MONOMAC1	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-1.4001287124370654	[197]	[85]	-8	hSpCas9	negative selection	12111016
170564592	170564615	6	-	28162770	MONOMAC1	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.702676895119304	[114]	[80]	-5	hSpCas9	negative selection	12111017
170566958	170566981	6	-	28162770	MONOMAC1	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.29014625145103523	[63]	[59]	-3	hSpCas9	negative selection	12111018
170561795	170561818	6	-	28162770	MONOMAC1	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.3756993513283431	[315]	[469]	4	hSpCas9	negative selection	12111019
170561812	170561835	6	-	28162770	MONOMAC1	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.5045458820339525	[223]	[180]	-4	hSpCas9	negative selection	12111020
170562061	170562084	6	+	28162770	MONOMAC1	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.2729089933216797	[173]	[240]	2	hSpCas9	negative selection	12111021
170562091	170562114	6	-	28162770	MONOMAC1	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.3432575879105976	[165]	[149]	-3	hSpCas9	negative selection	12111022
170562191	170562214	6	-	28162770	MONOMAC1	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	0.32828270723420083	[106]	[153]	3	hSpCas9	negative selection	12111023
170566941	170566964	6	+	28162770	OCIAML2	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-2.122706521821854	[21]	[27]	-8	hSpCas9	negative selection	12280380
170562223	170562246	6	-	28162770	OCIAML2	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-0.806595753529806	[70]	[224]	-5	hSpCas9	negative selection	12280381
170562077	170562100	6	-	28162770	OCIAML2	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-1.0588162268376038	[55]	[148]	-6	hSpCas9	negative selection	12280382
170564592	170564615	6	-	28162770	OCIAML2	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.4288096495475342	[33]	[139]	-3	hSpCas9	negative selection	12280383
170566958	170566981	6	-	28162770	OCIAML2	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-1.8185531286624679	[20]	[32]	-8	hSpCas9	negative selection	12280384
170561795	170561818	6	-	28162770	OCIAML2	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.1333336374090508	[87]	[534]	1	hSpCas9	negative selection	12280385
170561812	170561835	6	-	28162770	OCIAML2	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	-0.22085151611063414	[81]	[389]	-2	hSpCas9	negative selection	12280386
170562061	170562084	6	+	28162770	OCIAML2	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	-0.25973304274354275	[53]	[249]	-2	hSpCas9	negative selection	12280387
170562091	170562114	6	-	28162770	OCIAML2	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	-0.3080096244230823	[43]	[196]	-3	hSpCas9	negative selection	12280388
170562191	170562214	6	-	28162770	OCIAML2	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-1.7643610282988715	[37]	[61]	-8	hSpCas9	negative selection	12280389
170566941	170566964	6	+	28162770	OCIAML3	viability	GATAAGAGAGCCACGAACCACGG	TBP	ENSG00000112592	-2.316473664795254	[32]	[19]	-9	hSpCas9	negative selection	12449746
170562223	170562246	6	-	28162770	OCIAML3	viability	CGAAGTACTCACTGCAGCTGCGG	TBP	ENSG00000112592	-1.7000492777344878	[126]	[117]	-8	hSpCas9	negative selection	12449747
170562077	170562100	6	-	28162770	OCIAML3	viability	GAGCTGTGGTGCCTGGCCTGAGG	TBP	ENSG00000112592	-0.8835142575191479	[76]	[125]	-6	hSpCas9	negative selection	12449748
170564592	170564615	6	-	28162770	OCIAML3	viability	GTTTCGGGCACGAAGTGCAATGG	TBP	ENSG00000112592	-0.5595192639388726	[61]	[126]	-4	hSpCas9	negative selection	12449749
170566958	170566981	6	-	28162770	OCIAML3	viability	AGAACTGAAAATCAGTGCCGTGG	TBP	ENSG00000112592	-0.7956415014938139	[22]	[39]	-5	hSpCas9	negative selection	12449750
170561795	170561818	6	-	28162770	OCIAML3	viability	GATAGGGATTCCGGGAGTCATGG	TBP	ENSG00000112592	0.3975142057515322	[127]	[508]	3	hSpCas9	negative selection	12449751
170561812	170561835	6	-	28162770	OCIAML3	viability	GGCATCATTGGACTAAAGATAGG	TBP	ENSG00000112592	1.341157409279532	[127]	[978]	9	hSpCas9	negative selection	12449752
170562061	170562084	6	+	28162770	OCIAML3	viability	CAGGCAACACAGGGAACCTCAGG	TBP	ENSG00000112592	0.2183653565000655	[81]	[287]	2	hSpCas9	negative selection	12449753
170562091	170562114	6	-	28162770	OCIAML3	viability	GTCTGTGAGTGGAAGAGCTGTGG	TBP	ENSG00000112592	0.0203386671780873	[80]	[247]	0	hSpCas9	negative selection	12449754
170562191	170562214	6	-	28162770	OCIAML3	viability	AGAACTCTCCGAAGCTGGCGTGG	TBP	ENSG00000112592	-0.39347465295145456	[56]	[130]	-3	hSpCas9	negative selection	12449755