Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 79188
• Symbol: Tmem43
• Description: transmembrane protein 43

DataSource: http://genomecrispr.dkfz.de/#!/results/Tmem43

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
14131645	14131668	3	+	26472758	Jiyoye	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.18040451965885118	[219]	[187]	1	hSpCas9	negative selection	168496
14132537	14132560	3	+	26472758	Jiyoye	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.6136262589732999	[103]	[119]	4	hSpCas9	negative selection	168497
14132563	14132586	3	+	26472758	Jiyoye	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.4021410568850168	[183]	[104]	-3	hSpCas9	negative selection	168498
14134829	14134852	3	+	26472758	Jiyoye	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.2551722880608236	[159]	[143]	2	hSpCas9	negative selection	168499
14129477	14129500	3	+	26472758	Jiyoye	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.07067822595956752	[265]	[190]	0	hSpCas9	negative selection	168500
14131606	14131629	3	-	26472758	Jiyoye	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	-0.8923849003530343	[159]	[64]	-6	hSpCas9	negative selection	168501
14131632	14131655	3	+	26472758	Jiyoye	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.013667739454176098	[82]	[61]	0	hSpCas9	negative selection	168502
14134870	14134893	3	+	26472758	Jiyoye	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.44194079966655	[81]	[83]	3	hSpCas9	negative selection	168503
14131645	14131668	3	+	26472758	KBM7	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-0.2755431931583763	[973,724]	[408,252]	-3	hSpCas9	negative selection	359614
14132537	14132560	3	+	26472758	KBM7	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.6824096025701121	[717,510]	[373,532]	7	hSpCas9	negative selection	359615
14132563	14132586	3	+	26472758	KBM7	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.27646567997734317	[515,312]	[182,134]	-3	hSpCas9	negative selection	359616
14134829	14134852	3	+	26472758	KBM7	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.4360435103547704	[674,340]	[344,285]	5	hSpCas9	negative selection	359617
14129477	14129500	3	+	26472758	KBM7	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.10672542198827184	[736,786]	[417,362]	1	hSpCas9	negative selection	359618
14131606	14131629	3	-	26472758	KBM7	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.1908383921891718	[415,293]	[138,231]	2	hSpCas9	negative selection	359619
14131632	14131655	3	+	26472758	KBM7	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.7338205071811263	[362,356]	[317,250]	7	hSpCas9	negative selection	359620
14134870	14134893	3	+	26472758	KBM7	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.1839013290708834	[434,337]	[255,158]	1	hSpCas9	negative selection	359621
14131645	14131668	3	+	26472758	Raji	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.31854870128679325	[386]	[111]	3	hSpCas9	negative selection	550732
14132537	14132560	3	+	26472758	Raji	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	1.1073835353735995	[245]	[122]	8	hSpCas9	negative selection	550733
14132563	14132586	3	+	26472758	Raji	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.8078232535146916	[127]	[51]	7	hSpCas9	negative selection	550734
14134829	14134852	3	+	26472758	Raji	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.6355148134980797	[232]	[83]	6	hSpCas9	negative selection	550735
14129477	14129500	3	+	26472758	Raji	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.9784356781562152	[268]	[122]	8	hSpCas9	negative selection	550736
14131606	14131629	3	-	26472758	Raji	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.19071191897249548	[184]	[48]	1	hSpCas9	negative selection	550737
14131632	14131655	3	+	26472758	Raji	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.05767571089689694	[147]	[32]	0	hSpCas9	negative selection	550738
14134870	14134893	3	+	26472758	Raji	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	1.037749347536547	[190]	[90]	8	hSpCas9	negative selection	550739
14131645	14131668	3	+	26472758	K562	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-1.4017645986229006	[697]	[222]	-6	hSpCas9	negative selection	741850
14132537	14132560	3	+	26472758	K562	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.23514091407843618	[467]	[464]	1	hSpCas9	negative selection	741851
14132563	14132586	3	+	26472758	K562	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.0830245837084907	[273]	[244]	0	hSpCas9	negative selection	741852
14134829	14134852	3	+	26472758	K562	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.5223613407964135	[352]	[427]	4	hSpCas9	negative selection	741853
14129477	14129500	3	+	26472758	K562	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.10980985912422564	[541]	[423]	-1	hSpCas9	negative selection	741854
14131606	14131629	3	-	26472758	K562	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	-1.412436691536495	[431]	[136]	-6	hSpCas9	negative selection	741855
14131632	14131655	3	+	26472758	K562	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.10738201998299823	[308]	[280]	0	hSpCas9	negative selection	741856
14134870	14134893	3	+	26472758	K562	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.21294049619327876	[277]	[271]	1	hSpCas9	negative selection	741857
14125192	14125215	3	-	26627737	DLD1	viability	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.8064357056508982	[233]	[109,241,48]	7	hSpCas9	negative selection	819833
14129466	14129489	3	-	26627737	DLD1	viability	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.2241659577994619	[1117]	[379,338,489]	2	hSpCas9	negative selection	819838
14130818	14130841	3	-	26627737	DLD1	viability	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	-0.20113395149937774	[741]	[166,261,181]	-2	hSpCas9	negative selection	819840
14131611	14131634	3	+	26627737	DLD1	viability	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.2747509111194301	[354]	[80,98,94]	-3	hSpCas9	negative selection	819842
14132541	14132564	3	+	26627737	DLD1	viability	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	-0.305682508854232	[1008]	[149,257,343]	-3	hSpCas9	negative selection	819843
14133799	14133822	3	-	26627737	DLD1	viability	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.06625804325712403	[1006]	[496,171,236]	0	hSpCas9	negative selection	819844
14125192	14125215	3	-	26627737	GBM cells	viability after 5 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.21043352130267534	[136]	[61,64]	-3	hSpCas9	negative selection	902148
14129466	14129489	3	-	26627737	GBM cells	viability after 5 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.32272158379226124	[450]	[311,292]	5	hSpCas9	negative selection	902153
14130818	14130841	3	-	26627737	GBM cells	viability after 5 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	-0.46657841542496786	[352]	[107,165]	-6	hSpCas9	negative selection	902155
14131611	14131634	3	+	26627737	GBM cells	viability after 5 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.20125028703974623	[163]	[77,74]	-3	hSpCas9	negative selection	902157
14132541	14132564	3	+	26627737	GBM cells	viability after 5 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.04930411736243445	[536]	[267,327]	0	hSpCas9	negative selection	902158
14133799	14133822	3	-	26627737	GBM cells	viability after 5 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.18454235620683723	[426]	[216,185]	-3	hSpCas9	negative selection	902159
14125192	14125215	3	-	26627737	GBM cells	viability after 13 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.4728765936555803	[136]	[68,40]	-5	hSpCas9	negative selection	984463
14129466	14129489	3	-	26627737	GBM cells	viability after 13 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.5261173670186241	[450]	[358,346]	6	hSpCas9	negative selection	984468
14130818	14130841	3	-	26627737	GBM cells	viability after 13 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.3359069488612585	[352]	[281,208]	4	hSpCas9	negative selection	984470
14131611	14131634	3	+	26627737	GBM cells	viability after 13 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.930370845743085	[163]	[49,43]	-8	hSpCas9	negative selection	984472
14132541	14132564	3	+	26627737	GBM cells	viability after 13 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.4521866159930301	[536]	[466,342]	6	hSpCas9	negative selection	984473
14133799	14133822	3	-	26627737	GBM cells	viability after 13 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.00837910959586674	[426]	[296,180]	0	hSpCas9	negative selection	984474
14125192	14125215	3	-	26627737	GBM cells	viability after 21 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-1.840829324899544	[136]	[25,15]	-8	hSpCas9	negative selection	1066778
14129466	14129489	3	-	26627737	GBM cells	viability after 21 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.43751637333367266	[450]	[335,327]	4	hSpCas9	negative selection	1066783
14130818	14130841	3	-	26627737	GBM cells	viability after 21 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.161916373852816	[352]	[224,204]	1	hSpCas9	negative selection	1066785
14131611	14131634	3	+	26627737	GBM cells	viability after 21 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.08061879375288605	[163]	[89,78]	0	hSpCas9	negative selection	1066787
14132541	14132564	3	+	26627737	GBM cells	viability after 21 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.43805639561093557	[536]	[412,378]	4	hSpCas9	negative selection	1066788
14133799	14133822	3	-	26627737	GBM cells	viability after 21 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.2446708701113558	[426]	[289,260]	2	hSpCas9	negative selection	1066789
14125192	14125215	3	-	26627737	RPE1	viability after 9 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.2816613175433136	[173]	[69,212]	7	hSpCas9	negative selection	1149093
14129466	14129489	3	-	26627737	RPE1	viability after 9 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.46866561312713284	[1401]	[585,634]	3	hSpCas9	negative selection	1149098
14130818	14130841	3	-	26627737	RPE1	viability after 9 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	2.14190947787632	[254]	[271,455]	9	hSpCas9	negative selection	1149100
14131611	14131634	3	+	26627737	RPE1	viability after 9 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.09497595095778957	[886]	[228,299]	0	hSpCas9	negative selection	1149102
14132541	14132564	3	+	26627737	RPE1	viability after 9 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.9919108471066982	[1514]	[903,993]	6	hSpCas9	negative selection	1149103
14133799	14133822	3	-	26627737	RPE1	viability after 9 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.06705519074970084	[1139]	[310,378]	0	hSpCas9	negative selection	1149104
14125192	14125215	3	-	26627737	RPE1	viability after 12 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.5121646508435869	[173]	[110,156]	8	hSpCas9	negative selection	1231408
14129466	14129489	3	-	26627737	RPE1	viability after 12 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.8855473583221253	[1401]	[674,717]	5	hSpCas9	negative selection	1231413
14130818	14130841	3	-	26627737	RPE1	viability after 12 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	1.7659441194685601	[254]	[181,286]	8	hSpCas9	negative selection	1231415
14131611	14131634	3	+	26627737	RPE1	viability after 12 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.8648300165885862	[886]	[91,171]	-5	hSpCas9	negative selection	1231417
14132541	14132564	3	+	26627737	RPE1	viability after 12 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	1.1308459976581318	[1514]	[817,968]	6	hSpCas9	negative selection	1231418
14133799	14133822	3	-	26627737	RPE1	viability after 12 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.3294905661392002	[1139]	[336,144]	-2	hSpCas9	negative selection	1231419
14125192	14125215	3	-	26627737	RPE1	viability after 15 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.2583193262702288	[173]	[103,130]	7	hSpCas9	negative selection	1313723
14129466	14129489	3	-	26627737	RPE1	viability after 15 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.5560878282127991	[1401]	[520,642]	3	hSpCas9	negative selection	1313728
14130818	14130841	3	-	26627737	RPE1	viability after 15 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	1.636148545296268	[254]	[211,235]	8	hSpCas9	negative selection	1313730
14131611	14131634	3	+	26627737	RPE1	viability after 15 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.20761121859528198	[886]	[116,313]	-1	hSpCas9	negative selection	1313732
14132541	14132564	3	+	26627737	RPE1	viability after 15 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	1.1267150729378843	[1514]	[805,1060]	6	hSpCas9	negative selection	1313733
14133799	14133822	3	-	26627737	RPE1	viability after 15 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.12345047281986699	[1139]	[490,107]	-1	hSpCas9	negative selection	1313734
14125192	14125215	3	-	26627737	RPE1	viability after 18 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.5354941669857518	[173]	[95,178]	7	hSpCas9	negative selection	1396038
14129466	14129489	3	-	26627737	RPE1	viability after 18 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.7190688692952337	[1401]	[602,643]	4	hSpCas9	negative selection	1396043
14130818	14130841	3	-	26627737	RPE1	viability after 18 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	1.9001410094841804	[254]	[208,307]	8	hSpCas9	negative selection	1396045
14131611	14131634	3	+	26627737	RPE1	viability after 18 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.2901574844366118	[886]	[115,280]	-2	hSpCas9	negative selection	1396047
14132541	14132564	3	+	26627737	RPE1	viability after 18 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	1.3279675233316224	[1514]	[921,1137]	7	hSpCas9	negative selection	1396048
14133799	14133822	3	-	26627737	RPE1	viability after 18 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.06527855953242057	[1139]	[478,153]	0	hSpCas9	negative selection	1396049
14125192	14125215	3	-	26627737	HeLa	viability after 8 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.2367194744223653	[230]	[176,41,58]	-2	hSpCas9	negative selection	1478353
14129466	14129489	3	-	26627737	HeLa	viability after 8 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.8229146685270596	[517]	[337,359,478]	6	hSpCas9	negative selection	1478358
14130818	14130841	3	-	26627737	HeLa	viability after 8 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.02344680182519976	[505]	[171,249,236]	0	hSpCas9	negative selection	1478360
14131611	14131634	3	+	26627737	HeLa	viability after 8 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.7668673465882404	[229]	[101,10,71]	-6	hSpCas9	negative selection	1478362
14132541	14132564	3	+	26627737	HeLa	viability after 8 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	-0.0837069024594872	[1373]	[700,299,710]	-1	hSpCas9	negative selection	1478363
14133799	14133822	3	-	26627737	HeLa	viability after 8 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.8295266536558975	[564]	[762,382,249]	6	hSpCas9	negative selection	1478364
14125192	14125215	3	-	26627737	HeLa	viability after 12 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.8193363049459029	[230]	[360,35,127]	6	hSpCas9	negative selection	1560668
14129466	14129489	3	-	26627737	HeLa	viability after 12 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.6570501332464163	[517]	[374,391,240]	5	hSpCas9	negative selection	1560673
14130818	14130841	3	-	26627737	HeLa	viability after 12 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.0607537783281929	[505]	[303,272,73]	0	hSpCas9	negative selection	1560675
14131611	14131634	3	+	26627737	HeLa	viability after 12 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.2732880470965421	[229]	[122,122,97]	2	hSpCas9	negative selection	1560677
14132541	14132564	3	+	26627737	HeLa	viability after 12 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	-0.4528990043094627	[1373]	[585,343,326]	-4	hSpCas9	negative selection	1560678
14133799	14133822	3	-	26627737	HeLa	viability after 12 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.18594969315608145	[564]	[420,202,183]	1	hSpCas9	negative selection	1560679
14125192	14125215	3	-	26627737	HeLa	viability after 15 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.10331396875884025	[230]	[142,88,67]	0	hSpCas9	negative selection	1642983
14129466	14129489	3	-	26627737	HeLa	viability after 15 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	1.1080466236805857	[517]	[679,319,352]	7	hSpCas9	negative selection	1642988
14130818	14130841	3	-	26627737	HeLa	viability after 15 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.5997545785350314	[505]	[160,458,318]	5	hSpCas9	negative selection	1642990
14131611	14131634	3	+	26627737	HeLa	viability after 15 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.8017705025141764	[229]	[32,226,236]	6	hSpCas9	negative selection	1642992
14132541	14132564	3	+	26627737	HeLa	viability after 15 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.08177451953583281	[1373]	[739,526,499]	0	hSpCas9	negative selection	1642993
14133799	14133822	3	-	26627737	HeLa	viability after 15 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.06923137898231219	[564]	[73,312,276]	0	hSpCas9	negative selection	1642994
14125192	14125215	3	-	26627737	HeLa	viability after 18 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.08183570156530251	[230]	[91,74,67]	0	hSpCas9	negative selection	1725298
14129466	14129489	3	-	26627737	HeLa	viability after 18 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	1.1004679202590952	[517]	[449,266,352]	7	hSpCas9	negative selection	1725303
14130818	14130841	3	-	26627737	HeLa	viability after 18 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.6259427449718081	[505]	[103,398,318]	5	hSpCas9	negative selection	1725305
14131611	14131634	3	+	26627737	HeLa	viability after 18 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.822023715985161	[229]	[20,194,236]	6	hSpCas9	negative selection	1725307
14132541	14132564	3	+	26627737	HeLa	viability after 18 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.07824749869240666	[1373]	[489,440,499]	0	hSpCas9	negative selection	1725308
14133799	14133822	3	-	26627737	HeLa	viability after 18 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.060425813622649094	[564]	[49,261,276]	0	hSpCas9	negative selection	1725309
14125192	14125215	3	-	26627737	HCT116	viability after 6 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.9056529866456382	[133]	[52,31]	5	hSpCas9	negative selection	1807613
14129466	14129489	3	-	26627737	HCT116	viability after 6 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.8832198343184438	[928]	[532,123]	5	hSpCas9	negative selection	1807618
14130818	14130841	3	-	26627737	HCT116	viability after 6 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	2.245020407309568	[483]	[69,520]	9	hSpCas9	negative selection	1807620
14131611	14131634	3	+	26627737	HCT116	viability after 6 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	1.192962788806406	[534]	[83,251]	6	hSpCas9	negative selection	1807622
14132541	14132564	3	+	26627737	HCT116	viability after 6 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	1.2536865746750263	[1453]	[390,629]	6	hSpCas9	negative selection	1807623
14133799	14133822	3	-	26627737	HCT116	viability after 6 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.7823317532291808	[1148]	[231,34]	-4	hSpCas9	negative selection	1807624
14125192	14125215	3	-	26627737	HCT116	viability after 8 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.3610076847189738	[148]	[56,98,35]	-4	hSpCas9	negative selection	1889928
14129466	14129489	3	-	26627737	HCT116	viability after 8 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.03756484987057784	[490]	[425,154,254]	0	hSpCas9	negative selection	1889933
14130818	14130841	3	-	26627737	HCT116	viability after 8 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.40011323770881185	[310]	[143,227,303]	4	hSpCas9	negative selection	1889935
14131611	14131634	3	+	26627737	HCT116	viability after 8 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.21236431626909058	[158]	[107,124,71]	2	hSpCas9	negative selection	1889937
14132541	14132564	3	+	26627737	HCT116	viability after 8 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.3669412524943144	[541]	[340,455,357]	4	hSpCas9	negative selection	1889938
14133799	14133822	3	-	26627737	HCT116	viability after 8 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.16694133926509624	[404]	[228,178,188]	-2	hSpCas9	negative selection	1889939
14125192	14125215	3	-	26627737	HCT116	viability after 9 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.3735803131144455	[133]	[42,131]	8	hSpCas9	negative selection	1972243
14129466	14129489	3	-	26627737	HCT116	viability after 9 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.8828130445889729	[928]	[586,354]	6	hSpCas9	negative selection	1972248
14130818	14130841	3	-	26627737	HCT116	viability after 9 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	2.398133700806262	[483]	[306,976]	9	hSpCas9	negative selection	1972250
14131611	14131634	3	+	26627737	HCT116	viability after 9 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-1.8733363524583315	[534]	[81,4]	-8	hSpCas9	negative selection	1972252
14132541	14132564	3	+	26627737	HCT116	viability after 9 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.18566865956987666	[1453]	[459,426]	1	hSpCas9	negative selection	1972253
14133799	14133822	3	-	26627737	HCT116	viability after 9 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.023672597642038773	[1148]	[460,175]	0	hSpCas9	negative selection	1972254
14125192	14125215	3	-	26627737	HCT116	viability after 12 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.25452080677904654	[148]	[110,64,101]	2	hSpCas9	negative selection	2054558
14129466	14129489	3	-	26627737	HCT116	viability after 12 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	-0.08666843633552967	[490]	[196,283,252]	-1	hSpCas9	negative selection	2054563
14130818	14130841	3	-	26627737	HCT116	viability after 12 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.5124953842587583	[310]	[126,283,298]	5	hSpCas9	negative selection	2054565
14131611	14131634	3	+	26627737	HCT116	viability after 12 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.0025634718734277584	[158]	[93,70,83]	0	hSpCas9	negative selection	2054567
14132541	14132564	3	+	26627737	HCT116	viability after 12 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.7873003262999344	[541]	[637,413,407]	7	hSpCas9	negative selection	2054568
14133799	14133822	3	-	26627737	HCT116	viability after 12 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.19722225359963397	[404]	[262,351,117]	2	hSpCas9	negative selection	2054569
14125192	14125215	3	-	26627737	HCT116	viability after 15 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.06380662481964183	[148]	[142,55,75]	0	hSpCas9	negative selection	2136873
14129466	14129489	3	-	26627737	HCT116	viability after 15 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	-0.16467716656375753	[490]	[250,283,219]	-2	hSpCas9	negative selection	2136878
14130818	14130841	3	-	26627737	HCT116	viability after 15 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.8901696332698152	[310]	[345,491,158]	7	hSpCas9	negative selection	2136880
14131611	14131634	3	+	26627737	HCT116	viability after 15 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.4072053644905377	[158]	[78,75,52]	-4	hSpCas9	negative selection	2136882
14132541	14132564	3	+	26627737	HCT116	viability after 15 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.6811678031598317	[541]	[606,451,451]	6	hSpCas9	negative selection	2136883
14133799	14133822	3	-	26627737	HCT116	viability after 15 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.030552053692622205	[404]	[302,301,88]	0	hSpCas9	negative selection	2136884
14125192	14125215	3	-	26627737	HCT116	viability after 18 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.03964334893865762	[148]	[70,28,114]	0	hSpCas9	negative selection	2219188
14129466	14129489	3	-	26627737	HCT116	viability after 18 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.0665918752153486	[490]	[70,250,431]	0	hSpCas9	negative selection	2219193
14130818	14130841	3	-	26627737	HCT116	viability after 18 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.619014648614263	[310]	[167,168,365]	5	hSpCas9	negative selection	2219195
14131611	14131634	3	+	26627737	HCT116	viability after 18 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.3685146022500926	[158]	[126,93,75]	3	hSpCas9	negative selection	2219197
14132541	14132564	3	+	26627737	HCT116	viability after 18 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.8371754590793913	[541]	[654,351,401]	6	hSpCas9	negative selection	2219198
14133799	14133822	3	-	26627737	HCT116	viability after 18 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.1136982483311143	[404]	[175,179,284]	1	hSpCas9	negative selection	2219199
14125192	14125215	3	-	24336569	HL60	viability	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.44946542200744166	[534]	[1545]	4	hSpCas9	negative selection	2302167
14129410	14129433	3	+	24336569	HL60	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.10662582411057374	[455]	[1038]	1	hSpCas9	negative selection	2302168
14129416	14129439	3	-	24336569	HL60	viability	TTCTCTCCGGGTACTGGTACTGG	TMEM43	ENSG00000170876	-0.6011142113931822	[609]	[850]	-5	hSpCas9	negative selection	2302169
14129422	14129445	3	-	24336569	HL60	viability	GACATGTTCTCTCCGGGTACTGG	TMEM43	ENSG00000170876	-0.5297960400061643	[525]	[770]	-5	hSpCas9	negative selection	2302170
14129428	14129451	3	-	24336569	HL60	viability	AACTTTGACATGTTCTCTCCGGG	TMEM43	ENSG00000170876	-0.38212357876260716	[100]	[163]	-3	hSpCas9	negative selection	2302171
14129461	14129484	3	+	24336569	HL60	viability	CCCAGCCAGGCTTCCTGGAACGG	TMEM43	ENSG00000170876	0.5535390825918554	[169]	[527]	5	hSpCas9	negative selection	2302172
14129466	14129489	3	-	24336569	HL60	viability	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	-0.12780993843179797	[600]	[1163]	-1	hSpCas9	negative selection	2302173
14129474	14129497	3	-	24336569	HL60	viability	AGGTCTCGCTCAGCCGTTCCAGG	TMEM43	ENSG00000170876	0.9627625069684531	[521]	[2152]	7	hSpCas9	negative selection	2302174
14129481	14129504	3	+	24336569	HL60	viability	CGGCTGAGCGAGACCTCGGGTGG	TMEM43	ENSG00000170876	0.021929048591531962	[497]	[1069]	0	hSpCas9	negative selection	2302175
14129524	14129547	3	-	24336569	HL60	viability	TAGGTAGAAGGAGAGCAGGAAGG	TMEM43	ENSG00000170876	-0.840059710766645	[1119]	[1323]	-6	hSpCas9	negative selection	2302176
14125192	14125215	3	-	24336569	KBM7	viability	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.05183987193603434	[578]	[1636]	0	hSpCas9	negative selection	2369344
14129410	14129433	3	+	24336569	KBM7	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.43544468195776403	[320]	[1183]	4	hSpCas9	negative selection	2369345
14129416	14129439	3	-	24336569	KBM7	viability	TTCTCTCCGGGTACTGGTACTGG	TMEM43	ENSG00000170876	0.418451632836329	[264]	[965]	4	hSpCas9	negative selection	2369346
14129422	14129445	3	-	24336569	KBM7	viability	GACATGTTCTCTCCGGGTACTGG	TMEM43	ENSG00000170876	-1.0885658401758171	[360]	[462]	-7	hSpCas9	negative selection	2369347
14129428	14129451	3	-	24336569	KBM7	viability	AACTTTGACATGTTCTCTCCGGG	TMEM43	ENSG00000170876	0.21868340627412186	[68]	[218]	2	hSpCas9	negative selection	2369348
14129461	14129484	3	+	24336569	KBM7	viability	CCCAGCCAGGCTTCCTGGAACGG	TMEM43	ENSG00000170876	0.5626891389049448	[279]	[1127]	5	hSpCas9	negative selection	2369349
14129466	14129489	3	-	24336569	KBM7	viability	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.4340812842374071	[472]	[1742]	4	hSpCas9	negative selection	2369350
14129474	14129497	3	-	24336569	KBM7	viability	AGGTCTCGCTCAGCCGTTCCAGG	TMEM43	ENSG00000170876	0.4268899213672588	[605]	[2221]	4	hSpCas9	negative selection	2369351
14129481	14129504	3	+	24336569	KBM7	viability	CGGCTGAGCGAGACCTCGGGTGG	TMEM43	ENSG00000170876	0.0006946322038932085	[471]	[1287]	0	hSpCas9	negative selection	2369352
14129524	14129547	3	-	24336569	KBM7	viability	TAGGTAGAAGGAGAGCAGGAAGG	TMEM43	ENSG00000170876	-0.8221468090331836	[620]	[957]	-6	hSpCas9	negative selection	2369353
14124961	14124984	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATGAGGTACTGCAATGTCCCGG	TMEM43	ENSG00000170876	0.6545989118048235	[120,122]	[10,74]	3	dCas9-VP64	positive selection	2395156
14125047	14125070	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAACTGCAGTAAGTCCCGCTTGG	TMEM43	ENSG00000170876	1.345938590125111	[59,292]	[43,159]	5	dCas9-VP64	positive selection	2395157
14124979	14125002	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTGGAAACTATACGGTCCGGG	TMEM43	ENSG00000170876	1.24846696979647	[90,66]	[61,18]	5	dCas9-VP64	positive selection	2395158
14124961	14124984	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATGAGGTACTGCAATGTCCCGG	TMEM43	ENSG00000170876	-0.29036814391227006	[251,224]	[61,64]	-3	dCas9-VP64	positive selection	2490411
14125047	14125070	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAACTGCAGTAAGTCCCGCTTGG	TMEM43	ENSG00000170876	-0.0954539579285053	[122,277]	[25,92]	0	dCas9-VP64	positive selection	2490412
14124979	14125002	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTGGAAACTATACGGTCCGGG	TMEM43	ENSG00000170876	-1.1659443058510888	[141,385]	[27,45]	-9	dCas9-VP64	positive selection	2490413
14130824	14130847	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	0.20225190429934137	[4,4]	[4,4]	4	hSpCas9	positive selection	3027885
14131634	14131657	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	-0.05126629190935872	[4,5]	[3,3]	0	hSpCas9	positive selection	3027886
14129478	14129501	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.10464082951979684	[3,3]	[4,2]	2	hSpCas9	positive selection	3027887
14132538	14132561	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.16761609079898382	[4,4]	[4,3]	3	hSpCas9	positive selection	3027888
14130824	14130847	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	0.15910354531433546	[4,4]	[4,2]	3	hSpCas9	positive selection	3095743
14131634	14131657	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.17250222338187182	[4,4]	[4,2]	3	hSpCas9	positive selection	3095744
14129478	14129501	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.10554832278250029	[3,3]	[3,2]	1	hSpCas9	positive selection	3095745
14132538	14132561	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.32056377201648734	[4,4]	[4,3]	5	hSpCas9	positive selection	3095746
14130940	14130963		-	24336571	A375	resistance to PLX after 7 days	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.1322815991305789	[21,19]	[16,19]	-4	hSpCas9	positive selection	3151318
14129410	14129433		+	24336571	A375	resistance to PLX after 7 days	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.09212260776624787	[17,18]	[17,15]	-3	hSpCas9	positive selection	3151319
14130818	14130841		+	24336571	A375	resistance to PLX after 7 days	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	0.09597727561927916	[3,2]	[4,2]	3	hSpCas9	positive selection	3151320
14129477	14129500		+	24336571	A375	resistance to PLX after 7 days	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.17089269841269705	[6,6]	[4,6]	-5	hSpCas9	positive selection	3151321
14130925	14130948		+	24336571	A375	resistance to PLX after 7 days	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.15158394535091235	[21,23]	[25,24]	5	hSpCas9	positive selection	3151322
14130940	14130963		-	24336571	A375	resistance to PLX after 14 days	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.5649819978050652	[14,24]	[14,11]	5	hSpCas9	positive selection	3209111
14129410	14129433		+	24336571	A375	resistance to PLX after 14 days	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.41120062153158493	[19,23]	[5,7]	-5	hSpCas9	positive selection	3209112
14130818	14130841		+	24336571	A375	resistance to PLX after 14 days	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	1.6600706038168282	[3,2]	[4,5]	9	hSpCas9	positive selection	3209113
14129477	14129500		+	24336571	A375	resistance to PLX after 14 days	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.23309983903316733	[3,4]	[1,1]	-3	hSpCas9	positive selection	3209114
14130925	14130948		+	24336571	A375	resistance to PLX after 14 days	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	-0.04075587811610015	[17,34]	[11,11]	0	hSpCas9	positive selection	3209115
14130940	14130963		-	24336571	A375	viability after 7 days	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.4758425082981436	[14]	[21,19]	7	hSpCas9	negative selection	3266904
14129410	14129433		+	24336571	A375	viability after 7 days	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.2032740822961222	[21]	[17,18]	-3	hSpCas9	negative selection	3266905
14130818	14130841		+	24336571	A375	viability after 7 days	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	0.21271854094764087	[2]	[3,2]	3	hSpCas9	negative selection	3266906
14129477	14129500		+	24336571	A375	viability after 7 days	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.013379834552721737	[6]	[6,6]	0	hSpCas9	negative selection	3266907
14130925	14130948		+	24336571	A375	viability after 7 days	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.28572619116520426	[19]	[21,23]	4	hSpCas9	negative selection	3266908
14130940	14130963		-	24336571	A375	viability after 14 days	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.4479695309793155	[14]	[14,24]	6	hSpCas9	negative selection	3324697
14129410	14129433		+	24336571	A375	viability after 14 days	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.04755728118284963	[21]	[19,23]	0	hSpCas9	negative selection	3324698
14130818	14130841		+	24336571	A375	viability after 14 days	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	0.18617384371042212	[2]	[3,2]	2	hSpCas9	negative selection	3324699
14129477	14129500		+	24336571	A375	viability after 14 days	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.4400537489365205	[6]	[3,4]	-5	hSpCas9	negative selection	3324700
14130925	14130948		+	24336571	A375	viability after 14 days	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5178494339360967	[19]	[17,34]	6	hSpCas9	negative selection	3324701
14132537	14132560	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	3.2989053151972345	[170,170]	[10,10]	9	hSpCas9	positive selection	3398022
14129477	14129500	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3398023
14129410	14129433	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3398024
14130824	14130847	3	-	26780180	HT29	viability (Avana library 4 designs)	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	-0.267880999955226	[]	[]	-4	hSpCas9	negative selection	3466661
14131633	14131656	3	+	26780180	HT29	viability (Avana library 4 designs)	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	-0.00808393848658829	[]	[]	0	hSpCas9	negative selection	3466662
14129477	14129500	3	+	26780180	HT29	viability (Avana library 4 designs)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.174257976753109	[]	[]	0	hSpCas9	negative selection	3466663
14132537	14132560	3	+	26780180	HT29	viability (Avana library 4 designs)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	1.21185401214023	[]	[]	5	hSpCas9	negative selection	3466664
14131633	14131656	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	2.31262572071384	[]	[]	3	hSpCas9	negative selection	3570436
14130824	14130847	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	6.03941611569635	[]	[]	9	hSpCas9	negative selection	3570437
14132537	14132560	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	4.48048274178373	[]	[]	7	hSpCas9	negative selection	3570438
14129477	14129500	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	2.3485882352986	[]	[]	3	hSpCas9	negative selection	3570439
14133799	14133822	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.625430054202527	[]	[]	-1	hSpCas9	negative selection	3570440
14132542	14132565	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGGAGTACACCGAGGATGGG	TMEM43	ENSG00000170876	2.32524237742974	[]	[]	3	hSpCas9	negative selection	3570441
14131633	14131656	3	+	26780180	A375	viability (Avana lentiGuide)	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	-1.49239654992715	[]	[]	-2	hSpCas9	negative selection	3679095
14130824	14130847	3	-	26780180	A375	viability (Avana lentiGuide)	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	-0.998183834982554	[]	[]	-1	hSpCas9	negative selection	3679096
14132537	14132560	3	+	26780180	A375	viability (Avana lentiGuide)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.309872828227798	[]	[]	0	hSpCas9	negative selection	3679097
14129477	14129500	3	+	26780180	A375	viability (Avana lentiGuide)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.356291881231788	[]	[]	0	hSpCas9	negative selection	3679098
14133799	14133822	3	-	26780180	A375	viability (Avana lentiGuide)	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	2.3406328665833	[]	[]	2	hSpCas9	negative selection	3679099
14132542	14132565	3	+	26780180	A375	viability (Avana lentiGuide)	GCAGGGAGTACACCGAGGATGGG	TMEM43	ENSG00000170876	6.20954621932391	[]	[]	5	hSpCas9	negative selection	3679100
14131633	14131656	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	-0.022621160299722123	[5]	[6,4]	0	hSpCas9	positive selection	3787702
14130824	14130847	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	0.25249767013484	[6]	[7,6]	7	hSpCas9	positive selection	3787703
14132537	14132560	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.07295622924137968	[5]	[6,4]	2	hSpCas9	positive selection	3787704
14129477	14129500	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.17384713023579734	[4]	[5,5]	5	hSpCas9	positive selection	3787705
14133799	14133822	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.22761447588290346	[5]	[6,6]	6	hSpCas9	positive selection	3787706
14132542	14132565	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGGAGTACACCGAGGATGGG	TMEM43	ENSG00000170876	0.4033635088171947	[4]	[5,6]	9	hSpCas9	positive selection	3787707
14131633	14131656	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.2608995056254717	[6]	[6,6]	7	hSpCas9	positive selection	3896309
14130824	14130847	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTTGCCGTCTTCAATGCGCGG	TMEM43	ENSG00000170876	0.19045851411955933	[6]	[7,5]	5	hSpCas9	positive selection	3896310
14132537	14132560	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.04384678823577551	[6]	[5,5]	0	hSpCas9	positive selection	3896311
14129477	14129500	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.0751710065074492	[5]	[4,5]	1	hSpCas9	positive selection	3896312
14133799	14133822	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.17703880593541488	[7]	[6,7]	4	hSpCas9	positive selection	3896313
14132542	14132565	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGGAGTACACCGAGGATGGG	TMEM43	ENSG00000170876	-0.5614544270491947	[5]	[1,3]	-6	hSpCas9	positive selection	3896314
14130940	14130963	3	-	26780180	A375	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.312702270561985	[]	[]	0	hSpCas9	negative selection	4005708
14129410	14129433	3	+	26780180	A375	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.846229899613466	[]	[]	3	hSpCas9	negative selection	4005709
14129477	14129500	3	+	26780180	A375	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	1.35199699484741	[]	[]	7	hSpCas9	negative selection	4005710
14131632	14131655	3	+	26780180	A375	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.815027743392258	[]	[]	3	hSpCas9	negative selection	4005711
14132537	14132560	3	+	26780180	A375	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	1.14832845820089	[]	[]	6	hSpCas9	negative selection	4005712
14130925	14130948	3	+	26780180	A375	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.435359045468518	[]	[]	1	hSpCas9	negative selection	4005713
14130940	14130963	3	-	26780180	HT29	viability (GeCKOv2 library)	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.675256418235124	[]	[]	2	hSpCas9	negative selection	4113674
14129410	14129433	3	+	26780180	HT29	viability (GeCKOv2 library)	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	1.29345630703464	[]	[]	6	hSpCas9	negative selection	4113675
14129477	14129500	3	+	26780180	HT29	viability (GeCKOv2 library)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	1.69631701513138	[]	[]	8	hSpCas9	negative selection	4113676
14131632	14131655	3	+	26780180	HT29	viability (GeCKOv2 library)	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.925010963938809	[]	[]	4	hSpCas9	negative selection	4113677
14132537	14132560	3	+	26780180	HT29	viability (GeCKOv2 library)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.992470712719561	[]	[]	4	hSpCas9	negative selection	4113678
14130925	14130948	3	+	26780180	HT29	viability (GeCKOv2 library)	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.601533314023439	[]	[]	2	hSpCas9	negative selection	4113679
14130940	14130963	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.11828800552091306	[4]	[2,3]	3	hSpCas9	positive selection	4177799
14129410	14129433	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.11679983115091591	[3]	[2,2]	3	hSpCas9	positive selection	4177800
14130818	14130841	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	0.31993132788131473	[1]	[0,2]	7	hSpCas9	positive selection	4177801
14129477	14129500	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.7977867101306624	[3]	[1,0]	-9	hSpCas9	positive selection	4177802
14130925	14130948	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.08905388375735732	[4]	[2,3]	2	hSpCas9	positive selection	4177803
14130940	14130963	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.7594439697417251	[4]	[0,4,3,4]	5	hSpCas9	positive selection	4241821
14129410	14129433	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.414239777497728	[2]	[3,1,2,0]	3	hSpCas9	positive selection	4241822
14130818	14130841	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGCCGCGCATTGAAGACGG	TMEM43	ENSG00000170876	-0.3006767754332137	[2]	[0,1,0,0]	-4	hSpCas9	positive selection	4241823
14129477	14129500	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.5717390560090752	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4241824
14130925	14130948	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.01661824077008267	[4]	[3,3,1,0]	0	hSpCas9	positive selection	4241825
14130925	14130948	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.045835440223862024	[2]	[3,1]	0	hSpCas9	positive selection	4304023
14130940	14130963	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.4568153022305289	[4]	[4,4]	8	hSpCas9	positive selection	4304024
14131632	14131655	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.3166369337690425	[2]	[2,0]	-6	hSpCas9	positive selection	4304025
14132537	14132560	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.16137765910518848	[3]	[3,1]	-3	hSpCas9	positive selection	4368275
14129477	14129500	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.026870958178080384	[2]	[2,0]	0	hSpCas9	positive selection	4368276
14129410	14129433	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.08614430135063689	[1]	[0,0]	-2	hSpCas9	positive selection	4368277
14130940	14130962	3	-	27760321	OCIAML3	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.29232584360984326	[562,457]	[498,469]	3	hSpCas9	negative selection	4448373
14131612	14131634	3	+	27760321	OCIAML3	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.6275468541023752	[608,480]	[583,745]	7	hSpCas9	negative selection	4448374
14131634	14131656	3	+	27760321	OCIAML3	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.3660243742459307	[232,213]	[150,321]	4	hSpCas9	negative selection	4448375
14132899	14132921	3	+	27760321	OCIAML3	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	0.31301610455659684	[436,350]	[285,503]	3	hSpCas9	negative selection	4448376
14134771	14134793	3	-	27760321	OCIAML3	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	0.1149360793845689	[603,520]	[445,512]	1	hSpCas9	negative selection	4448377
14130940	14130962	3	-	27760321	OCIAML2	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.5580225823895603	[562,457]	[540,688]	7	hSpCas9	negative selection	4531836
14131612	14131634	3	+	27760321	OCIAML2	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.3564240270883606	[608,480]	[581,532]	5	hSpCas9	negative selection	4531837
14131634	14131656	3	+	27760321	OCIAML2	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.5534485614573098	[232,213]	[222,320]	7	hSpCas9	negative selection	4531838
14132899	14132921	3	+	27760321	OCIAML2	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	0.02350608529412196	[436,350]	[344,291]	0	hSpCas9	negative selection	4531839
14134771	14134793	3	-	27760321	OCIAML2	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	0.6952049510078908	[603,520]	[587,927]	8	hSpCas9	negative selection	4531840
14130940	14130962	3	-	27760321	MV411	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.9119349974187305	[562,457]	[620,644]	6	hSpCas9	negative selection	4615299
14131612	14131634	3	+	27760321	MV411	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.6868196086572766	[608,480]	[221,221]	-5	hSpCas9	negative selection	4615300
14131634	14131656	3	+	27760321	MV411	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	1.9139926120849857	[232,213]	[669,383]	9	hSpCas9	negative selection	4615301
14132899	14132921	3	+	27760321	MV411	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.7324617377387911	[436,350]	[155,154]	-5	hSpCas9	negative selection	4615302
14134771	14134793	3	-	27760321	MV411	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	0.11094491970128045	[603,520]	[344,481]	0	hSpCas9	negative selection	4615303
14130940	14130962	3	-	27760321	HL60	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.2422938675610791	[562,457]	[514,464]	3	hSpCas9	negative selection	4698762
14131612	14131634	3	+	27760321	HL60	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.22687503314750251	[608,480]	[540,492]	2	hSpCas9	negative selection	4698763
14131634	14131656	3	+	27760321	HL60	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.21352858382106543	[232,213]	[166,258]	2	hSpCas9	negative selection	4698764
14132899	14132921	3	+	27760321	HL60	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	0.24229965738218523	[436,350]	[346,411]	3	hSpCas9	negative selection	4698765
14134771	14134793	3	-	27760321	HL60	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.13822333805123901	[603,520]	[510,315]	-1	hSpCas9	negative selection	4698766
14130940	14130962	3	-	27760321	HT1080	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	1.6550291570548652	[457,357]	[583,432]	8	hSpCas9	negative selection	4782225
14131612	14131634	3	+	27760321	HT1080	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.9017830371668534	[480,375]	[35,151]	-4	hSpCas9	negative selection	4782226
14131634	14131656	3	+	27760321	HT1080	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	1.8787337919364613	[213,166]	[322,230]	8	hSpCas9	negative selection	4782227
14132899	14132921	3	+	27760321	HT1080	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	0.5470794415290747	[350,273]	[242,114]	3	hSpCas9	negative selection	4782228
14134771	14134793	3	-	27760321	HT1080	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	0.20811597507010243	[520,406]	[245,177]	1	hSpCas9	negative selection	4782229
14130940	14130962	3	-	27760321	HT29	viability after 7 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.19043806987186615	[457,357]	[611,713,474]	3	hSpCas9	negative selection	4865688
14131612	14131634	3	+	27760321	HT29	viability after 7 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.5722454523420348	[480,375]	[1120,606,772]	8	hSpCas9	negative selection	4865689
14131634	14131656	3	+	27760321	HT29	viability after 7 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.2652234569032701	[213,166]	[205,240,418]	4	hSpCas9	negative selection	4865690
14132899	14132921	3	+	27760321	HT29	viability after 7 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.5611091032081117	[350,273]	[323,260,239]	-7	hSpCas9	negative selection	4865691
14134771	14134793	3	-	27760321	HT29	viability after 7 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.07155953565974227	[520,406]	[834,512,397]	-1	hSpCas9	negative selection	4865692
14130940	14130962	3	-	27760321	HT29	viability after 25 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.6130461622229968	[457,357]	[576,935,624]	7	hSpCas9	negative selection	4949151
14131612	14131634	3	+	27760321	HT29	viability after 25 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.6490321001763113	[480,375]	[728,749,832]	7	hSpCas9	negative selection	4949152
14131634	14131656	3	+	27760321	HT29	viability after 25 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.5043521722778025	[213,166]	[311,302,310]	5	hSpCas9	negative selection	4949153
14132899	14132921	3	+	27760321	HT29	viability after 25 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.5436070627086251	[350,273]	[201,353,173]	-5	hSpCas9	negative selection	4949154
14134771	14134793	3	-	27760321	HT29	viability after 25 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.24311014379426982	[520,406]	[537,427,362]	-3	hSpCas9	negative selection	4949155
14130940	14130962	3	-	27760321	HT29	viability after 22 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.8920460056976065	[457,357]	[1247,713,651]	8	hSpCas9	negative selection	5032614
14131612	14131634	3	+	27760321	HT29	viability after 22 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.6225077829011996	[480,375]	[902,652,727]	7	hSpCas9	negative selection	5032615
14131634	14131656	3	+	27760321	HT29	viability after 22 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.14082417478466447	[213,166]	[256,230,239]	1	hSpCas9	negative selection	5032616
14132899	14132921	3	+	27760321	HT29	viability after 22 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.892538437767747	[350,273]	[214,199,167]	-6	hSpCas9	negative selection	5032617
14134771	14134793	3	-	27760321	HT29	viability after 22 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.655700063381434	[520,406]	[336,408,274]	-5	hSpCas9	negative selection	5032618
14130940	14130962	3	-	27760321	HT29	viability after 19 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.7354323125534069	[457,357]	[1128,563,677]	7	hSpCas9	negative selection	5116077
14131612	14131634	3	+	27760321	HT29	viability after 19 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.6917599289080061	[480,375]	[738,759,866]	7	hSpCas9	negative selection	5116078
14131634	14131656	3	+	27760321	HT29	viability after 19 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.2912608375084976	[213,166]	[200,357,234]	2	hSpCas9	negative selection	5116079
14132899	14132921	3	+	27760321	HT29	viability after 19 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.2989409037526078	[350,273]	[318,121,427]	-3	hSpCas9	negative selection	5116080
14134771	14134793	3	-	27760321	HT29	viability after 19 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.6007923111920613	[520,406]	[551,336,187]	-5	hSpCas9	negative selection	5116081
14130940	14130962	3	-	27760321	HT29	viability after 16 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.39778902821013506	[457,357]	[769,531,519]	4	hSpCas9	negative selection	5199540
14131612	14131634	3	+	27760321	HT29	viability after 16 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.793514689308263	[480,375]	[974,852,677]	8	hSpCas9	negative selection	5199541
14131634	14131656	3	+	27760321	HT29	viability after 16 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.46099528596463407	[213,166]	[235,279,358]	5	hSpCas9	negative selection	5199542
14132899	14132921	3	+	27760321	HT29	viability after 16 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.46635698974435696	[350,273]	[328,264,171]	-5	hSpCas9	negative selection	5199543
14134771	14134793	3	-	27760321	HT29	viability after 16 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.34089366720359693	[520,406]	[548,362,331]	-4	hSpCas9	negative selection	5199544
14130940	14130962	3	-	27760321	HT29	viability after 13 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.4580331219682351	[457,357]	[630,674,644]	6	hSpCas9	negative selection	5283003
14131612	14131634	3	+	27760321	HT29	viability after 13 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.3284590267344745	[480,375]	[804,506,563]	4	hSpCas9	negative selection	5283004
14131634	14131656	3	+	27760321	HT29	viability after 13 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.23574356153568032	[213,166]	[395,254,136]	3	hSpCas9	negative selection	5283005
14132899	14132921	3	+	27760321	HT29	viability after 13 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.4571875829071373	[350,273]	[102,381,304]	-5	hSpCas9	negative selection	5283006
14134771	14134793	3	-	27760321	HT29	viability after 13 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.14789115595470412	[520,406]	[728,259,468]	-2	hSpCas9	negative selection	5283007
14130940	14130962	3	-	27760321	HT29	viability after 10 days	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.47309902007806437	[457,357]	[839,799,488]	6	hSpCas9	negative selection	5366466
14131612	14131634	3	+	27760321	HT29	viability after 10 days	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.8355624974398728	[480,375]	[1125,870,866]	9	hSpCas9	negative selection	5366467
14131634	14131656	3	+	27760321	HT29	viability after 10 days	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.7604408264974003	[213,166]	[510,400,298]	9	hSpCas9	negative selection	5366468
14132899	14132921	3	+	27760321	HT29	viability after 10 days	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.30919727109685896	[350,273]	[263,263,412]	-4	hSpCas9	negative selection	5366469
14134771	14134793	3	-	27760321	HT29	viability after 10 days	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	-0.06437765963991782	[520,406]	[562,446,646]	-1	hSpCas9	negative selection	5366470
14130940	14130962	3	-	27760321	MOLM13	viability	CCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.6316748755340199	[562,457]	[484,408]	4	hSpCas9	negative selection	5449929
14131612	14131634	3	+	27760321	MOLM13	viability	TCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.26477330303672425	[608,480]	[365,367]	1	hSpCas9	negative selection	5449930
14131634	14131656	3	+	27760321	MOLM13	viability	CACGTGGAGATGTACCAATGGG	TMEM43	ENSG00000170876	0.3527632379016231	[232,213]	[113,200]	2	hSpCas9	negative selection	5449931
14132899	14132921	3	+	27760321	MOLM13	viability	AAAACTTCGACCGAGAGATTGG	TMEM43	ENSG00000170876	-0.7859351511953129	[436,350]	[17,221]	-5	hSpCas9	negative selection	5449932
14134771	14134793	3	-	27760321	MOLM13	viability	GTTGTCGACTTTGTCGATGAGG	TMEM43	ENSG00000170876	0.13215485696945362	[603,520]	[348,344]	0	hSpCas9	negative selection	5449933
14125564	14125587	3	+	27661255	K562	viability	GCTGGACGCGACCTCAGAGAGGG	TMEM43	ENSG00000170876	-0.06550227543112037	[667,753]	[648,449]	-3	dCas9-KRAB	negative selection	5518413
14124980	14125003	3	-	27661255	K562	viability	GTCCTGGAAACTATACGGTCCGG	TMEM43	ENSG00000170876	0.09259540775561326	[416,453]	[432,316]	3	dCas9-KRAB	negative selection	5518414
14125142	14125165	3	-	27661255	K562	viability	GCGCTGTTCAGCTAGGAAGTGGG	TMEM43	ENSG00000170876	0.08803215332626518	[954,924]	[844,758]	3	dCas9-KRAB	negative selection	5518415
14130925	14130948	3	+	27260156	BXPC3	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5532876227409014	[385]	[504,642,548,684]	9	hSpCas9	negative selection	5576483
14130940	14130963	3	-	27260156	BXPC3	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.16527418289784435	[1127]	[1085,1349,1568,1301]	3	hSpCas9	negative selection	5576484
14131632	14131655	3	+	27260156	BXPC3	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.2015941036274193	[309]	[311,416,395,366]	4	hSpCas9	negative selection	5576485
14132537	14132560	3	+	27260156	BXPC3	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.21978091590115095	[564]	[668,778,622,668]	5	hSpCas9	negative selection	5640735
14129477	14129500	3	+	27260156	BXPC3	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.29589921246454987	[257]	[313,284,390,338]	6	hSpCas9	negative selection	5640736
14129410	14129433	3	+	27260156	BXPC3	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.06346493938058506	[82]	[63,76,114,77]	-1	hSpCas9	negative selection	5640737
14130925	14130948	3	+	27260156	A673	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.304724476621246	[385]	[643,564,570,513]	7	hSpCas9	negative selection	5697734
14130940	14130963	3	-	27260156	A673	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.07762725452745634	[1127]	[1481,1379,1381,1480]	1	hSpCas9	negative selection	5697735
14131632	14131655	3	+	27260156	A673	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.16118987657395417	[309]	[436,354,410,467]	4	hSpCas9	negative selection	5697736
14132537	14132560	3	+	27260156	A673	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.1988223595754532	[564]	[670,843,814,767]	5	hSpCas9	negative selection	5761986
14129477	14129500	3	+	27260156	A673	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.3273527730897189	[257]	[380,321,435,416]	7	hSpCas9	negative selection	5761987
14129410	14129433	3	+	27260156	A673	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.15776196419004318	[82]	[115,109,123,93]	4	hSpCas9	negative selection	5761988
14130925	14130948	3	+	27260156	A375	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5033257441211466	[385]	[653,719,781,433]	7	hSpCas9	negative selection	5818985
14130940	14130963	3	-	27260156	A375	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.030587215813881352	[1127]	[924,1650,1576,1074]	0	hSpCas9	negative selection	5818986
14131632	14131655	3	+	27260156	A375	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.059825950905168956	[309]	[322,357,310,391]	-1	hSpCas9	negative selection	5818987
14132537	14132560	3	+	27260156	A375	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.08087102961173326	[564]	[713,560,731,493]	-1	hSpCas9	negative selection	5883237
14129477	14129500	3	+	27260156	A375	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.28122912822111834	[257]	[348,161,241,228]	-4	hSpCas9	negative selection	5883238
14129410	14129433	3	+	27260156	A375	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.11731454839915978	[82]	[115,119,39,85]	-2	hSpCas9	negative selection	5883239
14130925	14130948	3	+	27260156	COLO741	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.2257093833855614	[385]	[601,538,588]	5	hSpCas9	negative selection	5940236
14130940	14130963	3	-	27260156	COLO741	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.012269840991086856	[1127]	[1653,1420,1241]	0	hSpCas9	negative selection	5940237
14131632	14131655	3	+	27260156	COLO741	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.09163916001178418	[309]	[338,308,456]	-2	hSpCas9	negative selection	5940238
14132537	14132560	3	+	27260156	COLO741	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.12362920398321939	[564]	[656,597,725]	-3	hSpCas9	negative selection	6004488
14129477	14129500	3	+	27260156	COLO741	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.0733693339590672	[257]	[486,337,234]	1	hSpCas9	negative selection	6004489
14129410	14129433	3	+	27260156	COLO741	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.16054127574824495	[82]	[101,59,120]	-3	hSpCas9	negative selection	6004490
14130925	14130948	3	+	27260156	CAL120	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.43350685697675045	[385]	[915,586,485]	6	hSpCas9	negative selection	6061487
14130940	14130963	3	-	27260156	CAL120	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.050447066440300725	[1127]	[1646,1184,1278]	0	hSpCas9	negative selection	6061488
14131632	14131655	3	+	27260156	CAL120	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.3825240479816602	[309]	[354,272,268]	-5	hSpCas9	negative selection	6061489
14132537	14132560	3	+	27260156	CAL120	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.11468608773747607	[564]	[722,593,641]	-2	hSpCas9	negative selection	6125739
14129477	14129500	3	+	27260156	CAL120	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.011074438121803976	[257]	[412,245,310]	0	hSpCas9	negative selection	6125740
14129410	14129433	3	+	27260156	CAL120	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.3084478925386973	[82]	[58,75,110]	-4	hSpCas9	negative selection	6125741
14130925	14130948	3	+	27260156	CADOES1	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.536067216646454	[385]	[597,552,311,622]	8	hSpCas9	negative selection	6182738
14130940	14130963	3	-	27260156	CADOES1	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.018858186887969808	[1127]	[827,1246,1180,993]	0	hSpCas9	negative selection	6182739
14131632	14131655	3	+	27260156	CADOES1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.1486307498654853	[309]	[288,302,301,386]	2	hSpCas9	negative selection	6182740
14132537	14132560	3	+	27260156	CADOES1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.1089893785551454	[564]	[796,488,493,482]	2	hSpCas9	negative selection	6246990
14129477	14129500	3	+	27260156	CADOES1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.26898797859858203	[257]	[164,219,178,233]	-5	hSpCas9	negative selection	6246991
14129410	14129433	3	+	27260156	CADOES1	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.23241652502129506	[82]	[69,129,43,119]	4	hSpCas9	negative selection	6246992
14130925	14130948	3	+	27260156	EWS502	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.20072065090287525	[385]	[407,492,414,574]	3	hSpCas9	negative selection	6303989
14130940	14130963	3	-	27260156	EWS502	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.03481085010362217	[1127]	[1053,952,1332,1358]	0	hSpCas9	negative selection	6303990
14131632	14131655	3	+	27260156	EWS502	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.043472020063848094	[309]	[237,367,315,361]	-1	hSpCas9	negative selection	6303991
14132537	14132560	3	+	27260156	EWS502	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.08715732072105015	[564]	[725,492,565,757]	1	hSpCas9	negative selection	6368241
14129477	14129500	3	+	27260156	EWS502	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.13702638719132987	[257]	[168,219,393,448]	2	hSpCas9	negative selection	6368242
14129410	14129433	3	+	27260156	EWS502	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.5207017554350135	[82]	[212,96,148,28]	8	hSpCas9	negative selection	6368243
14130925	14130948	3	+	27260156	EW8	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.33115478837075596	[385]	[623,294,304,388]	6	hSpCas9	negative selection	6425240
14130940	14130963	3	-	27260156	EW8	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.11951356884334907	[1127]	[1199,986,775,1065]	2	hSpCas9	negative selection	6425241
14131632	14131655	3	+	27260156	EW8	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.15070167680127855	[309]	[327,211,207,170]	-3	hSpCas9	negative selection	6425242
14132537	14132560	3	+	27260156	EW8	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.22333075820721932	[564]	[635,555,481,482]	4	hSpCas9	negative selection	6489492
14129477	14129500	3	+	27260156	EW8	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.05913576072383919	[257]	[192,190,227,253]	1	hSpCas9	negative selection	6489493
14129410	14129433	3	+	27260156	EW8	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.05132229140809841	[82]	[134,79,33,42]	0	hSpCas9	negative selection	6489494
14130925	14130948	3	+	27260156	CORL105	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.41287493578200196	[385]	[451,663,610,673]	7	hSpCas9	negative selection	6546491
14130940	14130963	3	-	27260156	CORL105	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.080756882510578	[1127]	[1214,1365,1563,1460]	1	hSpCas9	negative selection	6546492
14131632	14131655	3	+	27260156	CORL105	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.40117964257410865	[309]	[436,361,653,491]	7	hSpCas9	negative selection	6546493
14132537	14132560	3	+	27260156	CORL105	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.20325060916153648	[564]	[865,719,758,704]	4	hSpCas9	negative selection	6610743
14129477	14129500	3	+	27260156	CORL105	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.42294218623703095	[257]	[391,427,412,386]	7	hSpCas9	negative selection	6610744
14129410	14129433	3	+	27260156	CORL105	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.3574657464802673	[82]	[117,153,91,127]	6	hSpCas9	negative selection	6610745
14130925	14130948	3	+	27260156	HS294T	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.6406626094541548	[385]	[392,131,133,263]	8	hSpCas9	negative selection	6667742
14130940	14130963	3	-	27260156	HS294T	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.4116219138774697	[1127]	[491,769,431,635]	5	hSpCas9	negative selection	6667743
14131632	14131655	3	+	27260156	HS294T	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.612023917550579	[309]	[117,187,160,288]	7	hSpCas9	negative selection	6667744
14132537	14132560	3	+	27260156	HS294T	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.17097110553947098	[564]	[249,127,186,209]	-2	hSpCas9	negative selection	6731994
14129477	14129500	3	+	27260156	HS294T	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.46743470522149155	[257]	[65,40,65,125]	-6	hSpCas9	negative selection	6731995
14129410	14129433	3	+	27260156	HS294T	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.5141240930111766	[82]	[50,36,33,63]	6	hSpCas9	negative selection	6731996
14130925	14130948	3	+	27260156	HCC44	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.2393021326985364	[385]	[541,350,385,772]	4	hSpCas9	negative selection	6788993
14130940	14130963	3	-	27260156	HCC44	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.20735064374241996	[1127]	[1555,1153,1729,1534]	3	hSpCas9	negative selection	6788994
14131632	14131655	3	+	27260156	HCC44	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.22315719221712904	[309]	[375,234,329,279]	-4	hSpCas9	negative selection	6788995
14132537	14132560	3	+	27260156	HCC44	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.218306713350631	[564]	[653,662,866,805]	3	hSpCas9	negative selection	6853245
14129477	14129500	3	+	27260156	HCC44	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.01868365163900465	[257]	[434,145,329,279]	0	hSpCas9	negative selection	6853246
14129410	14129433	3	+	27260156	HCC44	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.46720831422492415	[82]	[100,60,98,20]	-6	hSpCas9	negative selection	6853247
14130925	14130948	3	+	27260156	G402	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.7913014934358299	[385]	[968,1136,519,678]	8	hSpCas9	negative selection	6910244
14130940	14130963	3	-	27260156	G402	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.09401323989840193	[1127]	[2110,1069,1648,1126]	1	hSpCas9	negative selection	6910245
14131632	14131655	3	+	27260156	G402	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.08440800205341903	[309]	[191,469,506,244]	-1	hSpCas9	negative selection	6910246
14132537	14132560	3	+	27260156	G402	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.11501267361532813	[564]	[965,667,487,881]	1	hSpCas9	negative selection	6974496
14129477	14129500	3	+	27260156	G402	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.7095717214669386	[257]	[158,187,241,175]	-7	hSpCas9	negative selection	6974497
14129410	14129433	3	+	27260156	G402	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.5730343699417639	[82]	[239,170,135,72]	7	hSpCas9	negative selection	6974498
14130925	14130948	3	+	27260156	L33	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.06574157931193209	[385]	[404,175,224,422]	1	hSpCas9	negative selection	7031495
14130940	14130963	3	-	27260156	L33	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.15701990799291576	[1127]	[1255,576,694,1259]	3	hSpCas9	negative selection	7031496
14131632	14131655	3	+	27260156	L33	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.5721359650199888	[309]	[583,162,250,458]	9	hSpCas9	negative selection	7031497
14132537	14132560	3	+	27260156	L33	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.00547045851674699	[564]	[565,188,353,676]	0	hSpCas9	negative selection	7095747
14129477	14129500	3	+	27260156	L33	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.2530088902182597	[257]	[227,91,98,254]	-5	hSpCas9	negative selection	7095748
14129410	14129433	3	+	27260156	L33	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.6125866889929039	[82]	[256,28,58,82]	9	hSpCas9	negative selection	7095749
14130925	14130948	3	+	27260156	K562	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.25020737811006094	[385]	[683,460,285,241]	3	hSpCas9	negative selection	7152746
14130940	14130963	3	-	27260156	K562	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.03748473611237002	[1127]	[889,888,1388,744]	0	hSpCas9	negative selection	7152747
14131632	14131655	3	+	27260156	K562	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.0051879733147838225	[309]	[437,451,94,147]	0	hSpCas9	negative selection	7152748
14132537	14132560	3	+	27260156	K562	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.015065577707539912	[564]	[380,420,281,843]	0	hSpCas9	negative selection	7216998
14129477	14129500	3	+	27260156	K562	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.17135907347125456	[257]	[119,157,508,229]	2	hSpCas9	negative selection	7216999
14129410	14129433	3	+	27260156	K562	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.8297227285096611	[82]	[88,64,285,81]	9	hSpCas9	negative selection	7217000
14130925	14130948	3	+	27260156	HT29	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.3186879384186688	[385]	[758,738,502,386]	6	hSpCas9	negative selection	7273997
14130940	14130963	3	-	27260156	HT29	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.07432027787121154	[1127]	[1500,1390,1516,1364]	1	hSpCas9	negative selection	7273998
14131632	14131655	3	+	27260156	HT29	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.2046796381860414	[309]	[345,234,308,399]	-4	hSpCas9	negative selection	7273999
14132537	14132560	3	+	27260156	HT29	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.07413897775355999	[564]	[675,851,765,613]	1	hSpCas9	negative selection	7338249
14129477	14129500	3	+	27260156	HT29	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.060271844544940945	[257]	[276,288,347,285]	-1	hSpCas9	negative selection	7338250
14129410	14129433	3	+	27260156	HT29	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.2052666055497041	[82]	[98,63,92,192]	4	hSpCas9	negative selection	7338251
14130925	14130948	3	+	27260156	MHHES1	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.682991244893605	[385]	[827,870,703,461]	9	hSpCas9	negative selection	7395248
14130940	14130963	3	-	27260156	MHHES1	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.2368508977586874	[1127]	[1542,1576,1707,1208]	4	hSpCas9	negative selection	7395249
14131632	14131655	3	+	27260156	MHHES1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.37800882592784674	[309]	[608,625,303,329]	6	hSpCas9	negative selection	7395250
14132537	14132560	3	+	27260156	MHHES1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.08062277536083318	[564]	[672,725,907,432]	1	hSpCas9	negative selection	7459500
14129477	14129500	3	+	27260156	MHHES1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.25660754931521357	[257]	[377,205,216,190]	-5	hSpCas9	negative selection	7459501
14129410	14129433	3	+	27260156	MHHES1	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.8389917008176957	[82]	[165,222,82,191]	9	hSpCas9	negative selection	7459502
14130925	14130948	3	+	27260156	MEWO	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5317450338108538	[385]	[553,375,642]	9	hSpCas9	negative selection	7516499
14130940	14130963	3	-	27260156	MEWO	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.09593033352972902	[1127]	[1054,1177,1135]	2	hSpCas9	negative selection	7516500
14131632	14131655	3	+	27260156	MEWO	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.08986410688130897	[309]	[457,278,217]	2	hSpCas9	negative selection	7516501
14132537	14132560	3	+	27260156	MEWO	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.1136725237656411	[564]	[544,376,554]	-2	hSpCas9	negative selection	7580751
14129477	14129500	3	+	27260156	MEWO	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.11615501783346749	[257]	[242,220,207]	-3	hSpCas9	negative selection	7580752
14129410	14129433	3	+	27260156	MEWO	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.0253494739016773	[82]	[50,71,100]	0	hSpCas9	negative selection	7580753
14130925	14130948	3	+	27260156	LNCAPCLONEFGC	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.4245740281983993	[385]	[502,401,531,452]	6	hSpCas9	negative selection	7637750
14130940	14130963	3	-	27260156	LNCAPCLONEFGC	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.10207556837245257	[1127]	[1101,971,1323,1029]	1	hSpCas9	negative selection	7637751
14131632	14131655	3	+	27260156	LNCAPCLONEFGC	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.1562678421779175	[309]	[267,320,434,245]	2	hSpCas9	negative selection	7637752
14132537	14132560	3	+	27260156	LNCAPCLONEFGC	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.1558734033940592	[564]	[458,491,773,592]	2	hSpCas9	negative selection	7702002
14129477	14129500	3	+	27260156	LNCAPCLONEFGC	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.5061775310378458	[257]	[176,192,157,126]	-7	hSpCas9	negative selection	7702003
14129410	14129433	3	+	27260156	LNCAPCLONEFGC	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.355030868736121	[82]	[105,70,88,118]	5	hSpCas9	negative selection	7702004
14130925	14130948	3	+	27260156	PANC0327	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5387501910581971	[385]	[625,304,639,456]	7	hSpCas9	negative selection	7759001
14130940	14130963	3	-	27260156	PANC0327	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.003828556423003615	[1127]	[1219,903,750,1151]	0	hSpCas9	negative selection	7759002
14131632	14131655	3	+	27260156	PANC0327	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.7532266478345075	[309]	[612,340,629,300]	9	hSpCas9	negative selection	7759003
14132537	14132560	3	+	27260156	PANC0327	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.09528153407282888	[564]	[459,569,274,559]	-1	hSpCas9	negative selection	7823253
14129477	14129500	3	+	27260156	PANC0327	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.7624383716085408	[257]	[149,85,174,136]	-8	hSpCas9	negative selection	7823254
14129410	14129433	3	+	27260156	PANC0327	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.3785083338682327	[82]	[161,48,162,20]	5	hSpCas9	negative selection	7823255
14130925	14130948	3	+	27260156	NCIH2009	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.25245956926947777	[385]	[748,657,539]	3	hSpCas9	negative selection	7880252
14130940	14130963	3	-	27260156	NCIH2009	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.2595356078093578	[1127]	[2078,2087,1523]	3	hSpCas9	negative selection	7880253
14131632	14131655	3	+	27260156	NCIH2009	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.19193068522761664	[309]	[579,673,242]	2	hSpCas9	negative selection	7880254
14132537	14132560	3	+	27260156	NCIH2009	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.2130338753797733	[564]	[1010,993,755]	3	hSpCas9	negative selection	7944504
14129477	14129500	3	+	27260156	NCIH2009	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.36567590831421404	[257]	[415,209,240]	-5	hSpCas9	negative selection	7944505
14129410	14129433	3	+	27260156	NCIH2009	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.6033828072324559	[82]	[241,79,220]	8	hSpCas9	negative selection	7944506
14130925	14130948	3	+	27260156	NCIH1373	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.8592442871980793	[385]	[631,688,1081,185]	8	hSpCas9	negative selection	8001503
14130940	14130963	3	-	27260156	NCIH1373	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.16871839817020695	[1127]	[1668,1219,1540,340]	1	hSpCas9	negative selection	8001504
14131632	14131655	3	+	27260156	NCIH1373	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.07739828787429581	[309]	[212,379,345,92]	0	hSpCas9	negative selection	8001505
14132537	14132560	3	+	27260156	NCIH1373	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.5897393862794647	[564]	[1259,634,1219,198]	6	hSpCas9	negative selection	8065755
14129477	14129500	3	+	27260156	NCIH1373	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-1.1078542609617263	[257]	[377,24,33,39]	-8	hSpCas9	negative selection	8065756
14129410	14129433	3	+	27260156	NCIH1373	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.31944492503498756	[82]	[217,47,134,21]	3	hSpCas9	negative selection	8065757
14130925	14130948	3	+	27260156	PATU8902	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.8753885297708167	[385]	[564,1244,939,1234]	8	hSpCas9	negative selection	8122754
14130940	14130963	3	-	27260156	PATU8902	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.22359107381992316	[1127]	[1655,2047,1597,2118]	2	hSpCas9	negative selection	8122755
14131632	14131655	3	+	27260156	PATU8902	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.1141254673101334	[309]	[455,491,177,861]	1	hSpCas9	negative selection	8122756
14132537	14132560	3	+	27260156	PATU8902	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.6364019434317675	[564]	[1967,646,1116,1158]	6	hSpCas9	negative selection	8187006
14129477	14129500	3	+	27260156	PATU8902	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.10506783137391906	[257]	[22,481,425,389]	-1	hSpCas9	negative selection	8187007
14129410	14129433	3	+	27260156	PATU8902	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.46988904585378144	[82]	[61,102,3,198]	-4	hSpCas9	negative selection	8187008
14130925	14130948	3	+	27260156	PANC1	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.305876188764012	[385]	[456,548,337,328]	5	hSpCas9	negative selection	8244005
14130940	14130963	3	-	27260156	PANC1	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.1983339623227245	[1127]	[734,939,967,757]	-3	hSpCas9	negative selection	8244006
14131632	14131655	3	+	27260156	PANC1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.025132435843364886	[309]	[321,290,292,189]	0	hSpCas9	negative selection	8244007
14132537	14132560	3	+	27260156	PANC1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.2960883248461671	[564]	[655,774,571,432]	5	hSpCas9	negative selection	8308257
14129477	14129500	3	+	27260156	PANC1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.10967949183022374	[257]	[184,315,182,163]	-2	hSpCas9	negative selection	8308258
14129410	14129433	3	+	27260156	PANC1	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.35496957894784975	[82]	[35,114,149,71]	6	hSpCas9	negative selection	8308259
14130925	14130948	3	+	27260156	PANC0813	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.656375571688278	[385]	[940,698,636,606]	9	hSpCas9	negative selection	8365256
14130940	14130963	3	-	27260156	PANC0813	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.1520232156717951	[1127]	[1443,1780,1299,1363]	2	hSpCas9	negative selection	8365257
14131632	14131655	3	+	27260156	PANC0813	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.09342943143096605	[309]	[253,339,442,497]	1	hSpCas9	negative selection	8365258
14132537	14132560	3	+	27260156	PANC0813	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.12113050570812978	[564]	[899,604,566,823]	2	hSpCas9	negative selection	8429508
14129477	14129500	3	+	27260156	PANC0813	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.9878438406240408	[257]	[139,222,136,111]	-8	hSpCas9	negative selection	8429509
14129410	14129433	3	+	27260156	PANC0813	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.4558002195550195	[82]	[159,131,145,100]	7	hSpCas9	negative selection	8429510
14130925	14130948	3	+	27260156	RDES	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.4060954063916198	[385]	[470,466,760,696]	6	hSpCas9	negative selection	8486507
14130940	14130963	3	-	27260156	RDES	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.16984540888953203	[1127]	[1392,1144,1706,1623]	2	hSpCas9	negative selection	8486508
14131632	14131655	3	+	27260156	RDES	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.012960629883458252	[309]	[366,346,310,374]	0	hSpCas9	negative selection	8486509
14132537	14132560	3	+	27260156	RDES	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.051709418821134334	[564]	[569,637,780,720]	0	hSpCas9	negative selection	8550759
14129477	14129500	3	+	27260156	RDES	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.09765065582767207	[257]	[297,325,223,427]	1	hSpCas9	negative selection	8550760
14129410	14129433	3	+	27260156	RDES	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.5000628055162815	[82]	[114,84,162,191]	7	hSpCas9	negative selection	8550761
14130925	14130948	3	+	27260156	PC3	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.197368704497685	[385]	[210,357,679,691]	4	hSpCas9	negative selection	8607758
14130940	14130963	3	-	27260156	PC3	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.2741422859811806	[1127]	[804,1824,1501,1450]	6	hSpCas9	negative selection	8607759
14131632	14131655	3	+	27260156	PC3	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.2292869875918726	[309]	[205,265,263,313]	-5	hSpCas9	negative selection	8607760
14132537	14132560	3	+	27260156	PC3	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.01985586534124628	[564]	[360,498,918,685]	0	hSpCas9	negative selection	8672010
14129477	14129500	3	+	27260156	PC3	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.0784456011286816	[257]	[151,267,398,229]	-2	hSpCas9	negative selection	8672011
14129410	14129433	3	+	27260156	PC3	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.1256453880584174	[82]	[64,110,142,60]	3	hSpCas9	negative selection	8672012
14130925	14130948	3	+	27260156	PATU8988T	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.5717274965518251	[385]	[447,580,554,642]	8	hSpCas9	negative selection	8729009
14130940	14130963	3	-	27260156	PATU8988T	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.14408896944676952	[1127]	[1188,1131,1154,1346]	2	hSpCas9	negative selection	8729010
14131632	14131655	3	+	27260156	PATU8988T	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.270075096858446	[309]	[120,276,317,281]	-4	hSpCas9	negative selection	8729011
14132537	14132560	3	+	27260156	PATU8988T	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.12550194563010264	[564]	[376,458,949,576]	2	hSpCas9	negative selection	8793261
14129477	14129500	3	+	27260156	PATU8988T	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.5579860868393713	[257]	[235,245,500,480]	8	hSpCas9	negative selection	8793262
14129410	14129433	3	+	27260156	PATU8988T	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.1760829937038655	[82]	[27,56,104,93]	-3	hSpCas9	negative selection	8793263
14130925	14130948	3	+	27260156	T47D	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.20645604244717697	[385]	[592,506,490,484]	4	hSpCas9	negative selection	8850260
14130940	14130963	3	-	27260156	T47D	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.02597514964108627	[1127]	[1333,1305,1270,1248]	0	hSpCas9	negative selection	8850261
14131632	14131655	3	+	27260156	T47D	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.0335741634284219	[309]	[416,435,266,353]	0	hSpCas9	negative selection	8850262
14132537	14132560	3	+	27260156	T47D	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.018338044503642126	[564]	[691,594,694,690]	0	hSpCas9	negative selection	8914512
14129477	14129500	3	+	27260156	T47D	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.3738873083185239	[257]	[235,238,205,246]	-7	hSpCas9	negative selection	8914513
14129410	14129433	3	+	27260156	T47D	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.15189024996283296	[82]	[116,148,92,65]	3	hSpCas9	negative selection	8914514
14130925	14130948	3	+	27260156	SU8686	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.4533892483171357	[385]	[483,361,680,608]	7	hSpCas9	negative selection	8971511
14130940	14130963	3	-	27260156	SU8686	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.13534597932899928	[1127]	[1097,1220,1084,1566]	2	hSpCas9	negative selection	8971512
14131632	14131655	3	+	27260156	SU8686	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.5667520276544831	[309]	[452,396,398,597]	8	hSpCas9	negative selection	8971513
14132537	14132560	3	+	27260156	SU8686	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.07003276781387247	[564]	[488,539,540,570]	-1	hSpCas9	negative selection	9035763
14129477	14129500	3	+	27260156	SU8686	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.033757501664638534	[257]	[204,253,284,260]	0	hSpCas9	negative selection	9035764
14129410	14129433	3	+	27260156	SU8686	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.36941576018912947	[82]	[109,84,127,103]	6	hSpCas9	negative selection	9035765
14130925	14130948	3	+	27260156	SKES1	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.3147101611711632	[385]	[515,558,489,372]	6	hSpCas9	negative selection	9092762
14130940	14130963	3	-	27260156	SKES1	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	0.09698375134867687	[1127]	[1370,1277,1189,1016]	2	hSpCas9	negative selection	9092763
14131632	14131655	3	+	27260156	SKES1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.2822046786432073	[309]	[227,299,300,193]	-6	hSpCas9	negative selection	9092764
14132537	14132560	3	+	27260156	SKES1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.05870468492639941	[564]	[749,604,543,480]	1	hSpCas9	negative selection	9157014
14129477	14129500	3	+	27260156	SKES1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.25142297387784396	[257]	[305,293,222,77]	-5	hSpCas9	negative selection	9157015
14129410	14129433	3	+	27260156	SKES1	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.3565980169775229	[82]	[161,62,118,83]	7	hSpCas9	negative selection	9157016
14130925	14130948	3	+	27260156	TOV112D	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.11161167756590698	[385]	[425,533,306,431]	2	hSpCas9	negative selection	9214013
14130940	14130963	3	-	27260156	TOV112D	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.010210165394084925	[1127]	[1218,1185,1226,883]	0	hSpCas9	negative selection	9214014
14131632	14131655	3	+	27260156	TOV112D	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.17493465482923337	[309]	[300,435,391,290]	3	hSpCas9	negative selection	9214015
14132537	14132560	3	+	27260156	TOV112D	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.21472265987427108	[564]	[721,554,739,590]	4	hSpCas9	negative selection	9278265
14129477	14129500	3	+	27260156	TOV112D	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.13160401661116694	[257]	[162,472,256,105]	-3	hSpCas9	negative selection	9278266
14129410	14129433	3	+	27260156	TOV112D	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.41780794352376116	[82]	[59,224,43,137]	7	hSpCas9	negative selection	9278267
14130925	14130948	3	+	27260156	TC71	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	-0.14030217562083397	[385]	[286,376,389,453]	-4	hSpCas9	negative selection	9335264
14130940	14130963	3	-	27260156	TC71	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.013801892491726475	[1127]	[1215,1269,1038,1274]	0	hSpCas9	negative selection	9335265
14131632	14131655	3	+	27260156	TC71	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.14284408287707767	[309]	[350,409,357,347]	3	hSpCas9	negative selection	9335266
14132537	14132560	3	+	27260156	TC71	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.02159421301431519	[564]	[715,642,506,592]	0	hSpCas9	negative selection	9399516
14129477	14129500	3	+	27260156	TC71	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.10196452177930604	[257]	[376,186,204,260]	-3	hSpCas9	negative selection	9399517
14129410	14129433	3	+	27260156	TC71	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	0.21424279641042077	[82]	[65,125,109,111]	5	hSpCas9	negative selection	9399518
14130925	14130948	3	+	27260156	TC32	viability	TGCACATCATTGGCGCCTTACGG	TMEM43	ENSG00000170876	0.4028561569667516	[385]	[424,233,827,571]	7	hSpCas9	negative selection	9456515
14130940	14130963	3	-	27260156	TC32	viability	ACCTACCTTGGATGTCCGTAAGG	TMEM43	ENSG00000170876	-0.08275475722213921	[1127]	[836,869,1251,1102]	-1	hSpCas9	negative selection	9456516
14131632	14131655	3	+	27260156	TC32	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.15881821536202556	[309]	[268,165,373,274]	-3	hSpCas9	negative selection	9456517
14132537	14132560	3	+	27260156	TC32	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.003968691070808994	[564]	[431,396,750,612]	0	hSpCas9	negative selection	9520767
14129477	14129500	3	+	27260156	TC32	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.1952936502123297	[257]	[246,98,294,248]	-4	hSpCas9	negative selection	9520768
14129410	14129433	3	+	27260156	TC32	viability	AGTATTCCAGTACCAGTACCCGG	TMEM43	ENSG00000170876	-0.1987105693413831	[82]	[80,24,97,84]	-4	hSpCas9	negative selection	9520769
14125192	14125215	3	-	27869803	HPAFII	viability after 27 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.140961634417183	[145]	[231,116,NaN]	8	hSpCas9	negative selection	9582904
14129466	14129489	3	-	27869803	HPAFII	viability after 27 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.26284666620702657	[506]	[291,342,NaN]	2	hSpCas9	negative selection	9582909
14130818	14130841	3	-	27869803	HPAFII	viability after 27 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.9440744680116882	[252]	[190,309,NaN]	7	hSpCas9	negative selection	9582911
14131611	14131634	3	+	27869803	HPAFII	viability after 27 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	1.2198317170999795	[216]	[292,242,NaN]	8	hSpCas9	negative selection	9582913
14132541	14132564	3	+	27869803	HPAFII	viability after 27 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.3548680103323356	[628]	[393,446,NaN]	3	hSpCas9	negative selection	9582914
14133799	14133822	3	-	27869803	HPAFII	viability after 27 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.2659526137363587	[432]	[420,150,NaN]	2	hSpCas9	negative selection	9582915
14125192	14125215	3	-	27869803	HPAFII	viability after 15 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	-0.26569753888892145	[145]	[140,123,NaN]	-3	hSpCas9	negative selection	9665353
14129466	14129489	3	-	27869803	HPAFII	viability after 15 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.23042221817159136	[506]	[822,524,NaN]	2	hSpCas9	negative selection	9665358
14130818	14130841	3	-	27869803	HPAFII	viability after 15 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	0.6157738637770207	[252]	[391,431,NaN]	7	hSpCas9	negative selection	9665360
14131611	14131634	3	+	27869803	HPAFII	viability after 15 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	0.25779160758413766	[216]	[395,205,NaN]	3	hSpCas9	negative selection	9665362
14132541	14132564	3	+	27869803	HPAFII	viability after 15 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.382327586627067	[628]	[890,874,NaN]	4	hSpCas9	negative selection	9665363
14133799	14133822	3	-	27869803	HPAFII	viability after 15 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.30041368502679516	[432]	[515,291,NaN]	-3	hSpCas9	negative selection	9665364
14125192	14125215	3	-	27869803	ASPC1	viability after 36 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.13216102779190708	[312]	[74,271,28]	1	hSpCas9	negative selection	9747802
14129466	14129489	3	-	27869803	ASPC1	viability after 36 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.5440930271683249	[1219]	[273,650,833]	5	hSpCas9	negative selection	9747807
14130818	14130841	3	-	27869803	ASPC1	viability after 36 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	-0.4430806911234873	[806]	[214,217,190]	-4	hSpCas9	negative selection	9747809
14131611	14131634	3	+	27869803	ASPC1	viability after 36 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.02987385679304677	[473]	[240,88,162]	0	hSpCas9	negative selection	9747811
14132541	14132564	3	+	27869803	ASPC1	viability after 36 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.6202675943532541	[1258]	[1220,537,394]	6	hSpCas9	negative selection	9747812
14133799	14133822	3	-	27869803	ASPC1	viability after 36 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.13192274527532488	[971]	[230,553,321]	1	hSpCas9	negative selection	9747813
14125192	14125215	3	-	27869803	PATU8988S	viability after 35 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.03393108903028064	[199]	[67,96,NaN]	0	hSpCas9	negative selection	9830251
14129466	14129489	3	-	27869803	PATU8988S	viability after 35 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.1595981689347864	[1004]	[500,402,NaN]	1	hSpCas9	negative selection	9830256
14130818	14130841	3	-	27869803	PATU8988S	viability after 35 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	-0.6724479773218967	[767]	[226,160,NaN]	-6	hSpCas9	negative selection	9830258
14131611	14131634	3	+	27869803	PATU8988S	viability after 35 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.35722320353704384	[473]	[162,134,NaN]	-4	hSpCas9	negative selection	9830260
14132541	14132564	3	+	27869803	PATU8988S	viability after 35 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.26573984463875044	[946]	[477,438,NaN]	3	hSpCas9	negative selection	9830261
14133799	14133822	3	-	27869803	PATU8988S	viability after 35 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.06747387252631343	[979]	[227,525,NaN]	0	hSpCas9	negative selection	9830262
14125192	14125215	3	-	27869803	PATU8988S	viability after 31 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	0.5509611354317396	[199]	[100,136,NaN]	6	hSpCas9	negative selection	9912700
14129466	14129489	3	-	27869803	PATU8988S	viability after 31 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	0.45682279726303754	[1004]	[443,684,NaN]	5	hSpCas9	negative selection	9912705
14130818	14130841	3	-	27869803	PATU8988S	viability after 31 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	-0.5186496552395663	[767]	[211,215,NaN]	-5	hSpCas9	negative selection	9912707
14131611	14131634	3	+	27869803	PATU8988S	viability after 31 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	-0.17128338781819283	[473]	[195,131,NaN]	-2	hSpCas9	negative selection	9912709
14132541	14132564	3	+	27869803	PATU8988S	viability after 31 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.09907666393942205	[946]	[469,320,NaN]	1	hSpCas9	negative selection	9912710
14133799	14133822	3	-	27869803	PATU8988S	viability after 31 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	-0.1206822783085929	[979]	[215,541,NaN]	-1	hSpCas9	negative selection	9912711
14125192	14125215	3	-	27869803	HPAFII	viability after 35 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.3579117389286728	[145]	[259,109,NaN]	8	hSpCas9	negative selection	9995149
14129466	14129489	3	-	27869803	HPAFII	viability after 35 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	-0.05533998027063991	[506]	[143,362,NaN]	0	hSpCas9	negative selection	9995154
14130818	14130841	3	-	27869803	HPAFII	viability after 35 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	1.2683972459343689	[252]	[205,423,NaN]	8	hSpCas9	negative selection	9995156
14131611	14131634	3	+	27869803	HPAFII	viability after 35 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	1.161289047165571	[216]	[232,259,NaN]	7	hSpCas9	negative selection	9995158
14132541	14132564	3	+	27869803	HPAFII	viability after 35 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	0.7995936938382262	[628]	[605,495,NaN]	5	hSpCas9	negative selection	9995159
14133799	14133822	3	-	27869803	HPAFII	viability after 35 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.5399724345882727	[432]	[448,171,NaN]	3	hSpCas9	negative selection	9995160
14125192	14125215	3	-	27869803	HPAFII	viability after 31 days	GATACTCACATTCGCGGCCATGG	TMEM43	ENSG00000170876	1.2741518070721092	[145]	[268,120,NaN]	8	hSpCas9	negative selection	10077598
14129466	14129489	3	-	27869803	HPAFII	viability after 31 days	CTCAGCCGTTCCAGGAAGCCTGG	TMEM43	ENSG00000170876	-0.3048316864219698	[506]	[170,294,NaN]	-2	hSpCas9	negative selection	10077603
14130818	14130841	3	-	27869803	HPAFII	viability after 31 days	CCGTCTTCAATGCGCGGCCCTGG	TMEM43	ENSG00000170876	1.244656564092994	[252]	[167,519,NaN]	8	hSpCas9	negative selection	10077605
14131611	14131634	3	+	27869803	HPAFII	viability after 31 days	TTCCGGCTGTGAAACTGCGGAGG	TMEM43	ENSG00000170876	1.4230747333876526	[216]	[383,263,NaN]	9	hSpCas9	negative selection	10077607
14132541	14132564	3	+	27869803	HPAFII	viability after 31 days	TGCAGGGAGTACACCGAGGATGG	TMEM43	ENSG00000170876	1.0890280355120496	[628]	[760,739,NaN]	7	hSpCas9	negative selection	10077608
14133799	14133822	3	-	27869803	HPAFII	viability after 31 days	CCTGAGACTTACCTGACGAGAGG	TMEM43	ENSG00000170876	0.08405675846826133	[432]	[292,218,NaN]	0	hSpCas9	negative selection	10077609
14131645	14131668	3	+	28162770	P31FUJ	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.20626898706412375	[252]	[342]	2	hSpCas9	negative selection	10253492
14132537	14132560	3	+	28162770	P31FUJ	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.40797751094065193	[337]	[526]	4	hSpCas9	negative selection	10253493
14132563	14132586	3	+	28162770	P31FUJ	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.46440156087645534	[102]	[166]	5	hSpCas9	negative selection	10253494
14134829	14134852	3	+	28162770	P31FUJ	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.11512109900592822	[197]	[251]	1	hSpCas9	negative selection	10253495
14129477	14129500	3	+	28162770	P31FUJ	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.09881928667682771	[177]	[223]	1	hSpCas9	negative selection	10253496
14131606	14131629	3	-	28162770	P31FUJ	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.67227253816538	[211]	[396]	7	hSpCas9	negative selection	10253497
14131632	14131655	3	+	28162770	P31FUJ	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.5676663320579853	[239]	[417]	6	hSpCas9	negative selection	10253498
14134870	14134893	3	+	28162770	P31FUJ	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.3140605063718849	[242]	[354]	3	hSpCas9	negative selection	10253499
14131645	14131668	3	+	28162770	TF1	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10422858
14132537	14132560	3	+	28162770	TF1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	NaN	[NaN]	[387]	1	hSpCas9	negative selection	10422859
14132563	14132586	3	+	28162770	TF1	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10422860
14134829	14134852	3	+	28162770	TF1	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10422861
14129477	14129500	3	+	28162770	TF1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10422862
14131606	14131629	3	-	28162770	TF1	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	NaN	[NaN]	[243]	1	hSpCas9	negative selection	10422863
14131632	14131655	3	+	28162770	TF1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10422864
14134870	14134893	3	+	28162770	TF1	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10422865
14131645	14131668	3	+	28162770	SKM1	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.6879987450179286	[78]	[224]	6	hSpCas9	negative selection	10592224
14132537	14132560	3	+	28162770	SKM1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.07611868795878096	[87]	[163]	0	hSpCas9	negative selection	10592225
14132563	14132586	3	+	28162770	SKM1	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.9112690361190929	[49]	[46]	-6	hSpCas9	negative selection	10592226
14134829	14134852	3	+	28162770	SKM1	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.5930358012568383	[44]	[119]	6	hSpCas9	negative selection	10592227
14129477	14129500	3	+	28162770	SKM1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.5682451057762223	[77]	[92]	-4	hSpCas9	negative selection	10592228
14131606	14131629	3	-	28162770	SKM1	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	1.3981965099015305	[46]	[218]	9	hSpCas9	negative selection	10592229
14131632	14131655	3	+	28162770	SKM1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.01103552241202231	[56]	[99]	0	hSpCas9	negative selection	10592230
14134870	14134893	3	+	28162770	SKM1	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.5800967455493402	[55]	[147]	5	hSpCas9	negative selection	10592231
14131645	14131668	3	+	28162770	SKM1	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.6879987450179286	[78]	[224]	6	hSpCas9	negative selection	10761590
14132537	14132560	3	+	28162770	SKM1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.07611868795878096	[87]	[163]	0	hSpCas9	negative selection	10761591
14132563	14132586	3	+	28162770	SKM1	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.9112690361190929	[49]	[46]	-6	hSpCas9	negative selection	10761592
14134829	14134852	3	+	28162770	SKM1	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.5930358012568383	[44]	[119]	6	hSpCas9	negative selection	10761593
14129477	14129500	3	+	28162770	SKM1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.5682451057762223	[77]	[92]	-4	hSpCas9	negative selection	10761594
14131606	14131629	3	-	28162770	SKM1	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	1.3981965099015305	[46]	[218]	9	hSpCas9	negative selection	10761595
14131632	14131655	3	+	28162770	SKM1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.01103552241202231	[56]	[99]	0	hSpCas9	negative selection	10761596
14134870	14134893	3	+	28162770	SKM1	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.5800967455493402	[55]	[147]	5	hSpCas9	negative selection	10761597
14131645	14131668	3	+	28162770	PL21	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.31100020383888594	[312]	[168]	2	hSpCas9	negative selection	10930956
14132537	14132560	3	+	28162770	PL21	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.6018802911547063	[326]	[215]	5	hSpCas9	negative selection	10930957
14132563	14132586	3	+	28162770	PL21	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.602686169584967	[173]	[114]	5	hSpCas9	negative selection	10930958
14134829	14134852	3	+	28162770	PL21	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	-0.7656446701727669	[249]	[63]	-5	hSpCas9	negative selection	10930959
14129477	14129500	3	+	28162770	PL21	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-1.9925054634530754	[319]	[34]	-8	hSpCas9	negative selection	10930960
14131606	14131629	3	-	28162770	PL21	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.9903472299325058	[132]	[114]	8	hSpCas9	negative selection	10930961
14131632	14131655	3	+	28162770	PL21	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.8982492728385029	[142]	[115]	7	hSpCas9	negative selection	10930962
14134870	14134893	3	+	28162770	PL21	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.23157662593615425	[231]	[85]	-2	hSpCas9	negative selection	10930963
14131645	14131668	3	+	28162770	P31FUJ	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.20626898706412375	[252]	[342]	2	hSpCas9	negative selection	11100322
14132537	14132560	3	+	28162770	P31FUJ	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.40797751094065193	[337]	[526]	4	hSpCas9	negative selection	11100323
14132563	14132586	3	+	28162770	P31FUJ	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.46440156087645534	[102]	[166]	5	hSpCas9	negative selection	11100324
14134829	14134852	3	+	28162770	P31FUJ	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.11512109900592822	[197]	[251]	1	hSpCas9	negative selection	11100325
14129477	14129500	3	+	28162770	P31FUJ	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.09881928667682771	[177]	[223]	1	hSpCas9	negative selection	11100326
14131606	14131629	3	-	28162770	P31FUJ	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.67227253816538	[211]	[396]	7	hSpCas9	negative selection	11100327
14131632	14131655	3	+	28162770	P31FUJ	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.5676663320579853	[239]	[417]	6	hSpCas9	negative selection	11100328
14134870	14134893	3	+	28162770	P31FUJ	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.3140605063718849	[242]	[354]	3	hSpCas9	negative selection	11100329
14131645	14131668	3	+	28162770	OCIAML5	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.8038624512113028	[118]	[374]	7	hSpCas9	negative selection	11269688
14132537	14132560	3	+	28162770	OCIAML5	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.46784235638671323	[142]	[356]	4	hSpCas9	negative selection	11269689
14132563	14132586	3	+	28162770	OCIAML5	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.30344591720656144	[66]	[97]	-2	hSpCas9	negative selection	11269690
14134829	14134852	3	+	28162770	OCIAML5	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	-0.569666840163272	[110]	[134]	-4	hSpCas9	negative selection	11269691
14129477	14129500	3	+	28162770	OCIAML5	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.14793342913600288	[122]	[245]	1	hSpCas9	negative selection	11269692
14131606	14131629	3	-	28162770	OCIAML5	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.09705226013381887	[100]	[194]	0	hSpCas9	negative selection	11269693
14131632	14131655	3	+	28162770	OCIAML5	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.3253696898556999	[148]	[336]	2	hSpCas9	negative selection	11269694
14134870	14134893	3	+	28162770	OCIAML5	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.9865519030510173	[190]	[173]	-6	hSpCas9	negative selection	11269695
14131645	14131668	3	+	28162770	EOL1	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-0.04991713632232797	[447]	[227]	0	hSpCas9	negative selection	11439054
14132537	14132560	3	+	28162770	EOL1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.6851190149918458	[588]	[192]	-5	hSpCas9	negative selection	11439055
14132563	14132586	3	+	28162770	EOL1	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.11842750516456949	[291]	[166]	1	hSpCas9	negative selection	11439056
14134829	14134852	3	+	28162770	EOL1	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.26539902631533957	[408]	[258]	2	hSpCas9	negative selection	11439057
14129477	14129500	3	+	28162770	EOL1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.3206653571760151	[530]	[223]	-2	hSpCas9	negative selection	11439058
14131606	14131629	3	-	28162770	EOL1	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	-0.262330363152975	[213]	[93]	-2	hSpCas9	negative selection	11439059
14131632	14131655	3	+	28162770	EOL1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.7974358536671954	[165]	[151]	7	hSpCas9	negative selection	11439060
14134870	14134893	3	+	28162770	EOL1	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	1.0523033187689075	[215]	[235]	8	hSpCas9	negative selection	11439061
14131645	14131668	3	+	28162770	MOLM13	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.3731849575977174	[361]	[338]	2	hSpCas9	negative selection	11608420
14132537	14132560	3	+	28162770	MOLM13	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	1.0046427892231153	[354]	[514]	7	hSpCas9	negative selection	11608421
14132563	14132586	3	+	28162770	MOLM13	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.2990124695351325	[171]	[152]	2	hSpCas9	negative selection	11608422
14134829	14134852	3	+	28162770	MOLM13	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.6850212864203313	[313]	[364]	5	hSpCas9	negative selection	11608423
14129477	14129500	3	+	28162770	MOLM13	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.35619262691847386	[346]	[195]	-2	hSpCas9	negative selection	11608424
14131606	14131629	3	-	28162770	MOLM13	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	-0.5184356815583444	[209]	[105]	-3	hSpCas9	negative selection	11608425
14131632	14131655	3	+	28162770	MOLM13	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.4867187156414069	[218]	[112]	-3	hSpCas9	negative selection	11608426
14134870	14134893	3	+	28162770	MOLM13	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.6781256420608737	[373]	[168]	-4	hSpCas9	negative selection	11608427
14131645	14131668	3	+	28162770	HEL	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.40889289369411036	[273]	[232]	3	hSpCas9	negative selection	11777786
14132537	14132560	3	+	28162770	HEL	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.6498632664337383	[403]	[405]	5	hSpCas9	negative selection	11777787
14132563	14132586	3	+	28162770	HEL	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.21975764424970812	[179]	[98]	-1	hSpCas9	negative selection	11777788
14134829	14134852	3	+	28162770	HEL	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	-0.6816961184975803	[287]	[114]	-4	hSpCas9	negative selection	11777789
14129477	14129500	3	+	28162770	HEL	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-1.114126319603554	[364]	[107]	-6	hSpCas9	negative selection	11777790
14131606	14131629	3	-	28162770	HEL	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.3545509489382248	[242]	[198]	3	hSpCas9	negative selection	11777791
14131632	14131655	3	+	28162770	HEL	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.24845989288831047	[183]	[139]	2	hSpCas9	negative selection	11777792
14134870	14134893	3	+	28162770	HEL	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.6202955738334368	[311]	[129]	-4	hSpCas9	negative selection	11777793
14131645	14131668	3	+	28162770	MV411	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-0.39355898485270874	[314]	[201]	-3	hSpCas9	negative selection	11947152
14132537	14132560	3	+	28162770	MV411	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.4004819254284885	[276]	[307]	3	hSpCas9	negative selection	11947153
14132563	14132586	3	+	28162770	MV411	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.8054143314829598	[138]	[66]	-5	hSpCas9	negative selection	11947154
14134829	14134852	3	+	28162770	MV411	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	-1.0155968550510186	[299]	[124]	-6	hSpCas9	negative selection	11947155
14129477	14129500	3	+	28162770	MV411	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.21898533476297974	[180]	[130]	-2	hSpCas9	negative selection	11947156
14131606	14131629	3	-	28162770	MV411	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.7823148200676223	[126]	[183]	7	hSpCas9	negative selection	11947157
14131632	14131655	3	+	28162770	MV411	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.7949253460852687	[155]	[227]	7	hSpCas9	negative selection	11947158
14134870	14134893	3	+	28162770	MV411	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.20347698482466506	[189]	[138]	-1	hSpCas9	negative selection	11947159
14131645	14131668	3	+	28162770	MONOMAC1	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-0.4293277294622398	[194]	[165]	-4	hSpCas9	negative selection	12116518
14132537	14132560	3	+	28162770	MONOMAC1	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	-0.5626863193762337	[200]	[155]	-5	hSpCas9	negative selection	12116519
14132563	14132586	3	+	28162770	MONOMAC1	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	-0.5158590310790945	[115]	[92]	-4	hSpCas9	negative selection	12116520
14134829	14134852	3	+	28162770	MONOMAC1	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.913387142634097	[131]	[284]	8	hSpCas9	negative selection	12116521
14129477	14129500	3	+	28162770	MONOMAC1	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.7738168072809298	[174]	[342]	7	hSpCas9	negative selection	12116522
14131606	14131629	3	-	28162770	MONOMAC1	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	-0.24650552332385367	[88]	[85]	-2	hSpCas9	negative selection	12116523
14131632	14131655	3	+	28162770	MONOMAC1	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.24353574432642777	[97]	[132]	2	hSpCas9	negative selection	12116524
14134870	14134893	3	+	28162770	MONOMAC1	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.24856714769963578	[113]	[109]	-2	hSpCas9	negative selection	12116525
14131645	14131668	3	+	28162770	OCIAML2	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	-0.004966252893349399	[41]	[231]	0	hSpCas9	negative selection	12285884
14132537	14132560	3	+	28162770	OCIAML2	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.7556026171021052	[66]	[626]	7	hSpCas9	negative selection	12285885
14132563	14132586	3	+	28162770	OCIAML2	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.8450120067977699	[22]	[228]	7	hSpCas9	negative selection	12285886
14134829	14134852	3	+	28162770	OCIAML2	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.7344846046624512	[35]	[331]	7	hSpCas9	negative selection	12285887
14129477	14129500	3	+	28162770	OCIAML2	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	0.03685392280127775	[50]	[289]	0	hSpCas9	negative selection	12285888
14131606	14131629	3	-	28162770	OCIAML2	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	0.7323102334281141	[23]	[220]	7	hSpCas9	negative selection	12285889
14131632	14131655	3	+	28162770	OCIAML2	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	0.8761729382842304	[22]	[233]	8	hSpCas9	negative selection	12285890
14134870	14134893	3	+	28162770	OCIAML2	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	0.5154309837999649	[25]	[205]	5	hSpCas9	negative selection	12285891
14131645	14131668	3	+	28162770	OCIAML3	viability	GTACCAATGGGTAGAAACTGAGG	TMEM43	ENSG00000170876	0.7447942731275954	[67]	[343]	6	hSpCas9	negative selection	12455250
14132537	14132560	3	+	28162770	OCIAML3	viability	TCCCTGCAGGGAGTACACCGAGG	TMEM43	ENSG00000170876	0.06401832258671658	[76]	[242]	0	hSpCas9	negative selection	12455251
14132563	14132586	3	+	28162770	OCIAML3	viability	GGCAGGTGAAGAAGGAGACGAGG	TMEM43	ENSG00000170876	0.47248777146274357	[52]	[221]	4	hSpCas9	negative selection	12455252
14134829	14134852	3	+	28162770	OCIAML3	viability	CATGTGGACATCATTCGCCGTGG	TMEM43	ENSG00000170876	0.6960950087078013	[54]	[268]	6	hSpCas9	negative selection	12455253
14129477	14129500	3	+	28162770	OCIAML3	viability	GGAACGGCTGAGCGAGACCTCGG	TMEM43	ENSG00000170876	-0.23036929355196345	[74]	[192]	-2	hSpCas9	negative selection	12455254
14131606	14131629	3	-	28162770	OCIAML3	viability	GCAGTTTCACAGCCGGAAGATGG	TMEM43	ENSG00000170876	1.1474593460769837	[47]	[320]	8	hSpCas9	negative selection	12455255
14131632	14131655	3	+	28162770	OCIAML3	viability	GGCACGTGGAGATGTACCAATGG	TMEM43	ENSG00000170876	-0.8935679221830712	[47]	[77]	-6	hSpCas9	negative selection	12455256
14134870	14134893	3	+	28162770	OCIAML3	viability	CGAAAATCCCAAGTATCCAGAGG	TMEM43	ENSG00000170876	-0.5719813339941642	[64]	[131]	-4	hSpCas9	negative selection	12455257