Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7320
• Symbol: UBE2B
• Description: ubiquitin conjugating enzyme E2 B

DataSource: http://genomecrispr.dkfz.de/#!/results/UBE2B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
134374396	134374419	5	-	26472758	Jiyoye	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.8666070001431707	[79]	[109]	6	hSpCas9	negative selection	176221
134388356	134388379	5	-	26472758	Jiyoye	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	-0.10558573953755035	[340]	[238]	0	hSpCas9	negative selection	176222
134371591	134371614	5	+	26472758	Jiyoye	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	1.5930419268172074	[39]	[90]	8	hSpCas9	negative selection	176223
134374424	134374447	5	+	26472758	Jiyoye	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.24490131507381985	[65]	[41]	-2	hSpCas9	negative selection	176224
134374383	134374406	5	+	26472758	Jiyoye	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.09774762129016534	[297]	[209]	0	hSpCas9	negative selection	176225
134371603	134371626	5	-	26472758	Jiyoye	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	1.0488748969535493	[240]	[375]	7	hSpCas9	negative selection	176226
134376673	134376696	5	+	26472758	Jiyoye	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.1027819459110223	[183]	[148]	0	hSpCas9	negative selection	176227
134374371	134374394	5	+	26472758	Jiyoye	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.07497631363150731	[87]	[62]	0	hSpCas9	negative selection	176228
134388315	134388338	5	+	26472758	Jiyoye	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.01666020136109836	[349]	[266]	0	hSpCas9	negative selection	176229
134371618	134371641	5	+	26472758	Jiyoye	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.21635303917029514	[112]	[98]	1	hSpCas9	negative selection	176230
134374396	134374419	5	-	26472758	KBM7	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5209338743122046	[581,480]	[138,203]	-4	hSpCas9	negative selection	367339
134388356	134388379	5	-	26472758	KBM7	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.14412043661953322	[1436,1733]	[831,838]	1	hSpCas9	negative selection	367340
134371591	134371614	5	+	26472758	KBM7	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	1.0837136204605873	[257,216]	[334,146]	9	hSpCas9	negative selection	367341
134374424	134374447	5	+	26472758	KBM7	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.21693970579636246	[197,121]	[118,55]	2	hSpCas9	negative selection	367342
134374383	134374406	5	+	26472758	KBM7	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.546133143364846	[810,676]	[459,551]	6	hSpCas9	negative selection	367343
134371603	134371626	5	-	26472758	KBM7	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.753553559699489	[1081,615]	[734,587]	8	hSpCas9	negative selection	367344
134376673	134376696	5	+	26472758	KBM7	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.0202890877763675	[547,493]	[370,608]	9	hSpCas9	negative selection	367345
134374371	134374394	5	+	26472758	KBM7	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.36043410284484123	[247,262]	[165,145]	4	hSpCas9	negative selection	367346
134388315	134388338	5	+	26472758	KBM7	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.4060883306231866	[1539,1606]	[821,1134]	4	hSpCas9	negative selection	367347
134371618	134371641	5	+	26472758	KBM7	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.5375319055374105	[510,380]	[247,348]	6	hSpCas9	negative selection	367348
134374396	134374419	5	-	26472758	Raji	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.39117650137419063	[229]	[69]	4	hSpCas9	negative selection	558457
134388356	134388379	5	-	26472758	Raji	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.4920016387745896	[670]	[218]	5	hSpCas9	negative selection	558458
134371591	134371614	5	+	26472758	Raji	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.47179496158247514	[86]	[27]	4	hSpCas9	negative selection	558459
134374424	134374447	5	+	26472758	Raji	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.37747269874134387	[135]	[40]	3	hSpCas9	negative selection	558460
134374383	134374406	5	+	26472758	Raji	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.14612809634168777	[452]	[94]	-1	hSpCas9	negative selection	558461
134371603	134371626	5	-	26472758	Raji	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.3162206468185811	[442]	[127]	3	hSpCas9	negative selection	558462
134376673	134376696	5	+	26472758	Raji	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.1526127893665972	[313]	[161]	8	hSpCas9	negative selection	558463
134374371	134374394	5	+	26472758	Raji	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.021899481571366897	[104]	[23]	0	hSpCas9	negative selection	558464
134388315	134388338	5	+	26472758	Raji	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.3046701054664227	[643]	[120]	-3	hSpCas9	negative selection	558465
134371618	134371641	5	+	26472758	Raji	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.5755323711120056	[239]	[82]	5	hSpCas9	negative selection	558466
134374396	134374419	5	-	26472758	K562	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.011009490941931266	[481]	[409]	0	hSpCas9	negative selection	749575
134388356	134388379	5	-	26472758	K562	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.3921432653278236	[1316]	[1458]	3	hSpCas9	negative selection	749576
134371591	134371614	5	+	26472758	K562	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-0.4902908925593912	[212]	[127]	-3	hSpCas9	negative selection	749577
134374424	134374447	5	+	26472758	K562	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.08089995642168946	[212]	[169]	0	hSpCas9	negative selection	749578
134374383	134374406	5	+	26472758	K562	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.3275143434299092	[505]	[535]	2	hSpCas9	negative selection	749579
134371603	134371626	5	-	26472758	K562	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5572061686973403	[664]	[825]	4	hSpCas9	negative selection	749580
134376673	134376696	5	+	26472758	K562	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.8515769745017991	[386]	[1178]	9	hSpCas9	negative selection	749581
134374371	134374394	5	+	26472758	K562	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.5169445824775385	[201]	[243]	4	hSpCas9	negative selection	749582
134388315	134388338	5	+	26472758	K562	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.7724706662989362	[1352]	[1950]	6	hSpCas9	negative selection	749583
134371618	134371641	5	+	26472758	K562	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.8989221616406802	[431]	[679]	7	hSpCas9	negative selection	749584
134371586	134371609	5	+	26627737	DLD1	viability	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.8136005171239616	[226]	[205,118,58]	7	hSpCas9	negative selection	826866
134374379	134374402	5	-	26627737	DLD1	viability	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.9101589247331847	[494]	[305,276,288]	8	hSpCas9	negative selection	826867
134374396	134374419	5	-	26627737	DLD1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.6651052323114642	[518]	[219,304,249]	6	hSpCas9	negative selection	826868
134374399	134374422	5	-	26627737	DLD1	viability	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.6208955912311489	[143]	[19,54,15]	-6	hSpCas9	negative selection	826869
134390319	134390342	5	+	26627737	DLD1	viability	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	1.1718696921035185	[556]	[406,468,315]	9	hSpCas9	negative selection	826870
134371586	134371609	5	+	26627737	GBM cells	viability after 5 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.02931051214136049	[147]	[99,61]	0	hSpCas9	negative selection	909181
134374379	134374402	5	-	26627737	GBM cells	viability after 5 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.20342491669563867	[399]	[242,250]	3	hSpCas9	negative selection	909182
134374396	134374419	5	-	26627737	GBM cells	viability after 5 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.22084196977304785	[291]	[164,199]	3	hSpCas9	negative selection	909183
134374399	134374422	5	-	26627737	GBM cells	viability after 5 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.37238814693170896	[69]	[32,24]	-5	hSpCas9	negative selection	909184
134390319	134390342	5	+	26627737	GBM cells	viability after 5 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.12057003948714984	[559]	[296,355]	2	hSpCas9	negative selection	909185
134371586	134371609	5	+	26627737	GBM cells	viability after 13 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.4790572214842535	[147]	[101,119]	6	hSpCas9	negative selection	991496
134374379	134374402	5	-	26627737	GBM cells	viability after 13 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.2961988509414498	[399]	[287,248]	4	hSpCas9	negative selection	991497
134374396	134374419	5	-	26627737	GBM cells	viability after 13 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.23496906677671472	[291]	[277,111]	3	hSpCas9	negative selection	991498
134374399	134374422	5	-	26627737	GBM cells	viability after 13 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.17130754253489755	[69]	[41,26]	-2	hSpCas9	negative selection	991499
134390319	134390342	5	+	26627737	GBM cells	viability after 13 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.24113284525790712	[559]	[389,333]	3	hSpCas9	negative selection	991500
134371586	134371609	5	+	26627737	GBM cells	viability after 21 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.9900004365105788	[147]	[154,163]	8	hSpCas9	negative selection	1073811
134374379	134374402	5	-	26627737	GBM cells	viability after 21 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.1500643968881894	[399]	[237,243]	1	hSpCas9	negative selection	1073812
134374396	134374419	5	-	26627737	GBM cells	viability after 21 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.05682810289172477	[291]	[152,175]	0	hSpCas9	negative selection	1073813
134374399	134374422	5	-	26627737	GBM cells	viability after 21 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-2.543686120548931	[69]	[5,6]	-9	hSpCas9	negative selection	1073814
134390319	134390342	5	+	26627737	GBM cells	viability after 21 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.4738716314444069	[559]	[456,390]	5	hSpCas9	negative selection	1073815
134371586	134371609	5	+	26627737	RPE1	viability after 9 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.05434628088187454	[1058]	[290,412]	0	hSpCas9	negative selection	1156126
134374379	134374402	5	-	26627737	RPE1	viability after 9 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.8369205153505255	[1108]	[610,631]	5	hSpCas9	negative selection	1156127
134374396	134374419	5	-	26627737	RPE1	viability after 9 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.6103667674674929	[470]	[249,192]	4	hSpCas9	negative selection	1156128
134374399	134374422	5	-	26627737	RPE1	viability after 9 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.9776200940216779	[301]	[245,108]	6	hSpCas9	negative selection	1156129
134390319	134390342	5	+	26627737	RPE1	viability after 9 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	1.5516407802609966	[1128]	[1019,1056]	8	hSpCas9	negative selection	1156130
134371586	134371609	5	+	26627737	RPE1	viability after 12 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.4602830868916263	[1058]	[216,195]	-3	hSpCas9	negative selection	1238441
134374379	134374402	5	-	26627737	RPE1	viability after 12 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.5980513847668087	[1108]	[535,360]	4	hSpCas9	negative selection	1238442
134374396	134374419	5	-	26627737	RPE1	viability after 12 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.5534691479185674	[470]	[158,213]	3	hSpCas9	negative selection	1238443
134374399	134374422	5	-	26627737	RPE1	viability after 12 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.39260980005737245	[301]	[123,87]	2	hSpCas9	negative selection	1238444
134390319	134390342	5	+	26627737	RPE1	viability after 12 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	1.8077332467273606	[1128]	[956,1172]	8	hSpCas9	negative selection	1238445
134371586	134371609	5	+	26627737	RPE1	viability after 15 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.4562796408775929	[1058]	[198,236]	-3	hSpCas9	negative selection	1320756
134374379	134374402	5	-	26627737	RPE1	viability after 15 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.46329173334901286	[1108]	[431,432]	3	hSpCas9	negative selection	1320757
134374396	134374419	5	-	26627737	RPE1	viability after 15 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.3729398112042914	[470]	[85,255]	2	hSpCas9	negative selection	1320758
134374399	134374422	5	-	26627737	RPE1	viability after 15 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.3654454792197088	[301]	[134,85]	2	hSpCas9	negative selection	1320759
134390319	134390342	5	+	26627737	RPE1	viability after 15 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	1.7393975903854555	[1128]	[1242,895]	8	hSpCas9	negative selection	1320760
134371586	134371609	5	+	26627737	RPE1	viability after 18 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.3339578771595749	[1058]	[218,234]	-2	hSpCas9	negative selection	1403071
134374379	134374402	5	-	26627737	RPE1	viability after 18 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.4570368142805873	[1108]	[507,306]	3	hSpCas9	negative selection	1403072
134374396	134374419	5	-	26627737	RPE1	viability after 18 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.2994702195693719	[470]	[168,142]	2	hSpCas9	negative selection	1403073
134374399	134374422	5	-	26627737	RPE1	viability after 18 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.5907174002057208	[301]	[187,52]	3	hSpCas9	negative selection	1403074
134390319	134390342	5	+	26627737	RPE1	viability after 18 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	1.6084910305128814	[1128]	[872,988]	8	hSpCas9	negative selection	1403075
134371586	134371609	5	+	26627737	HeLa	viability after 8 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.9112841502764871	[386]	[52,153,55]	-7	hSpCas9	negative selection	1485386
134374379	134374402	5	-	26627737	HeLa	viability after 8 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.2112181121645036	[791]	[735,312,233]	2	hSpCas9	negative selection	1485387
134374396	134374419	5	-	26627737	HeLa	viability after 8 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.8017512857493421	[1001]	[248,130,361]	-7	hSpCas9	negative selection	1485388
134374399	134374422	5	-	26627737	HeLa	viability after 8 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.554249476618293	[140]	[24,59,36]	-5	hSpCas9	negative selection	1485389
134390319	134390342	5	+	26627737	HeLa	viability after 8 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.33347309168045824	[1515]	[842,364,438]	-3	hSpCas9	negative selection	1485390
134371586	134371609	5	+	26627737	HeLa	viability after 12 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.7716071199135347	[386]	[16,91,169]	-6	hSpCas9	negative selection	1567701
134374379	134374402	5	-	26627737	HeLa	viability after 12 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	-0.18815512397044543	[791]	[289,314,253]	-2	hSpCas9	negative selection	1567702
134374396	134374419	5	-	26627737	HeLa	viability after 12 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.7016871415988792	[1001]	[24,154,195]	-9	hSpCas9	negative selection	1567703
134374399	134374422	5	-	26627737	HeLa	viability after 12 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.7483056438924967	[140]	[5,17,80]	-6	hSpCas9	negative selection	1567704
134390319	134390342	5	+	26627737	HeLa	viability after 12 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.23378536477114142	[1515]	[729,476,402]	-2	hSpCas9	negative selection	1567705
134371586	134371609	5	+	26627737	HeLa	viability after 15 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.2110974255667273	[386]	[97,46,57]	-8	hSpCas9	negative selection	1650016
134374379	134374402	5	-	26627737	HeLa	viability after 15 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.10309854631834181	[791]	[443,339,245]	0	hSpCas9	negative selection	1650017
134374396	134374419	5	-	26627737	HeLa	viability after 15 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.35449283862028946	[1001]	[474,198,277]	-3	hSpCas9	negative selection	1650018
134374399	134374422	5	-	26627737	HeLa	viability after 15 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-1.8041520688469908	[140]	[0,1,48]	-9	hSpCas9	negative selection	1650019
134390319	134390342	5	+	26627737	HeLa	viability after 15 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.07511443351903901	[1515]	[625,695,626]	0	hSpCas9	negative selection	1650020
134371586	134371609	5	+	26627737	HeLa	viability after 18 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.1839823572198283	[386]	[64,42,57]	-8	hSpCas9	negative selection	1732331
134374379	134374402	5	-	26627737	HeLa	viability after 18 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.07250896171562449	[791]	[280,284,245]	0	hSpCas9	negative selection	1732332
134374396	134374419	5	-	26627737	HeLa	viability after 18 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.4030287832601255	[1001]	[297,164,277]	-3	hSpCas9	negative selection	1732333
134374399	134374422	5	-	26627737	HeLa	viability after 18 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-1.8130147634334006	[140]	[0,0,48]	-9	hSpCas9	negative selection	1732334
134390319	134390342	5	+	26627737	HeLa	viability after 18 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.07754182284699862	[1515]	[415,583,626]	0	hSpCas9	negative selection	1732335
134371586	134371609	5	+	26627737	HCT116	viability after 6 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.5496913251314837	[192]	[104,10]	3	hSpCas9	negative selection	1814646
134374379	134374402	5	-	26627737	HCT116	viability after 6 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	1.665677453615548	[620]	[602,147]	8	hSpCas9	negative selection	1814647
134374396	134374419	5	-	26627737	HCT116	viability after 6 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	2.419173315016333	[606]	[958,262]	9	hSpCas9	negative selection	1814648
134374399	134374422	5	-	26627737	HCT116	viability after 6 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-2.6339126271525446	[342]	[18,2]	-9	hSpCas9	negative selection	1814649
134390319	134390342	5	+	26627737	HCT116	viability after 6 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.03355654337824099	[1560]	[129,317]	0	hSpCas9	negative selection	1814650
134371586	134371609	5	+	26627737	HCT116	viability after 8 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.4604445647288742	[317]	[39,119,30]	-9	hSpCas9	negative selection	1896961
134374379	134374402	5	-	26627737	HCT116	viability after 8 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.9522123366528585	[260]	[265,242,324]	8	hSpCas9	negative selection	1896962
134374396	134374419	5	-	26627737	HCT116	viability after 8 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.016749915128957182	[353]	[202,98,288]	0	hSpCas9	negative selection	1896963
134374399	134374422	5	-	26627737	HCT116	viability after 8 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-0.558370206487733	[124]	[60,67,11]	-6	hSpCas9	negative selection	1896964
134390319	134390342	5	+	26627737	HCT116	viability after 8 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.24727717876007982	[989]	[497,466,414]	-3	hSpCas9	negative selection	1896965
134371586	134371609	5	+	26627737	HCT116	viability after 9 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.19297121568190123	[192]	[116,12]	1	hSpCas9	negative selection	1979276
134374379	134374402	5	-	26627737	HCT116	viability after 9 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.8038476479596417	[620]	[241,326]	6	hSpCas9	negative selection	1979277
134374396	134374419	5	-	26627737	HCT116	viability after 9 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	1.146045675917009	[606]	[208,476]	7	hSpCas9	negative selection	1979278
134374399	134374422	5	-	26627737	HCT116	viability after 9 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-3.5057469490178312	[342]	[16,0]	-9	hSpCas9	negative selection	1979279
134390319	134390342	5	+	26627737	HCT116	viability after 9 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.3023855743422561	[1560]	[337,337]	-2	hSpCas9	negative selection	1979280
134371586	134371609	5	+	26627737	HCT116	viability after 12 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.3070208954655954	[317]	[178,118,102]	-3	hSpCas9	negative selection	2061591
134374379	134374402	5	-	26627737	HCT116	viability after 12 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.9647631073857952	[260]	[233,181,387]	8	hSpCas9	negative selection	2061592
134374396	134374419	5	-	26627737	HCT116	viability after 12 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.017249337071086612	[353]	[188,156,217]	0	hSpCas9	negative selection	2061593
134374399	134374422	5	-	26627737	HCT116	viability after 12 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-1.5393587650549077	[124]	[40,14,9]	-9	hSpCas9	negative selection	2061594
134390319	134390342	5	+	26627737	HCT116	viability after 12 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.11389485561241797	[989]	[422,463,559]	-1	hSpCas9	negative selection	2061595
134371586	134371609	5	+	26627737	HCT116	viability after 15 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.555805637871486	[317]	[60,44,79]	-8	hSpCas9	negative selection	2143906
134374379	134374402	5	-	26627737	HCT116	viability after 15 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	1.1123110244258583	[260]	[335,262,373]	8	hSpCas9	negative selection	2143907
134374396	134374419	5	-	26627737	HCT116	viability after 15 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.20771774432265083	[353]	[265,194,246]	2	hSpCas9	negative selection	2143908
134374399	134374422	5	-	26627737	HCT116	viability after 15 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-1.1194412259825437	[124]	[24,27,44]	-8	hSpCas9	negative selection	2143909
134390319	134390342	5	+	26627737	HCT116	viability after 15 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.4478625215117171	[989]	[447,367,437]	-5	hSpCas9	negative selection	2143910
134371586	134371609	5	+	26627737	HCT116	viability after 18 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.3752116642133811	[317]	[30,51,96]	-8	hSpCas9	negative selection	2226221
134374379	134374402	5	-	26627737	HCT116	viability after 18 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.9228474186561437	[260]	[280,124,322]	7	hSpCas9	negative selection	2226222
134374396	134374419	5	-	26627737	HCT116	viability after 18 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.44263830322436604	[353]	[136,127,111]	-4	hSpCas9	negative selection	2226223
134374399	134374422	5	-	26627737	HCT116	viability after 18 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	-1.0505318456588888	[124]	[2,52,29]	-7	hSpCas9	negative selection	2226224
134390319	134390342	5	+	26627737	HCT116	viability after 18 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	-0.34474732091909455	[989]	[400,286,451]	-3	hSpCas9	negative selection	2226225
134371604	134371627	5	-	24336569	HL60	viability	GCATGAGCCTCCTCCGGGCCGGG	UBE2B	ENSG00000119048	0.826142295064209	[402]	[1511]	6	hSpCas9	negative selection	2304649
134371609	134371632	5	-	24336569	HL60	viability	ATCCCGCATGAGCCTCCTCCGGG	UBE2B	ENSG00000119048	-0.9015962959390056	[240]	[272]	-7	hSpCas9	negative selection	2304650
134371618	134371641	5	+	24336569	HL60	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.9107752833423542	[232]	[926]	7	hSpCas9	negative selection	2304651
134374371	134374394	5	+	24336569	HL60	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.2721728539858044	[152]	[390]	2	hSpCas9	negative selection	2304652
134374379	134374402	5	-	24336569	HL60	viability	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	1.9621251679187863	[162]	[1343]	9	hSpCas9	negative selection	2304653
134374384	134374407	5	+	24336569	HL60	viability	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	1.0372196160586875	[241]	[1050]	7	hSpCas9	negative selection	2304654
134374393	134374416	5	+	24336569	HL60	viability	GACCCACCTGTGGGTGTCAGTGG	UBE2B	ENSG00000119048	-0.023842068811376224	[453]	[944]	0	hSpCas9	negative selection	2304655
134374399	134374422	5	-	24336569	HL60	viability	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.14709808794775814	[899]	[2108]	1	hSpCas9	negative selection	2304656
134374441	134374464	5	+	24336569	HL60	viability	CAGTGGAATGCAGTTATATTTGG	UBE2B	ENSG00000119048	0.8697403955362595	[217]	[842]	7	hSpCas9	negative selection	2304657
134380757	134380780	5	-	24336569	HL60	viability	CTAACAGTTGGTGGTTTATTTGG	UBE2B	ENSG00000119048	0.7722659189411925	[292]	[1058]	6	hSpCas9	negative selection	2304658
134371604	134371627	5	-	24336569	KBM7	viability	GCATGAGCCTCCTCCGGGCCGGG	UBE2B	ENSG00000119048	0.7120256196295056	[264]	[1183]	6	hSpCas9	negative selection	2371826
134371609	134371632	5	-	24336569	KBM7	viability	ATCCCGCATGAGCCTCCTCCGGG	UBE2B	ENSG00000119048	-1.638627489556949	[128]	[112]	-8	hSpCas9	negative selection	2371827
134371618	134371641	5	+	24336569	KBM7	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.026514083243830477	[355]	[988]	0	hSpCas9	negative selection	2371828
134374371	134374394	5	+	24336569	KBM7	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.1924055238147769	[402]	[1255]	1	hSpCas9	negative selection	2371829
134374379	134374402	5	-	24336569	KBM7	viability	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	-0.015215821109755834	[268]	[725]	0	hSpCas9	negative selection	2371830
134374384	134374407	5	+	24336569	KBM7	viability	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	1.113536562217906	[243]	[1439]	8	hSpCas9	negative selection	2371831
134374393	134374416	5	+	24336569	KBM7	viability	GACCCACCTGTGGGTGTCAGTGG	UBE2B	ENSG00000119048	-0.029559072596181124	[301]	[806]	0	hSpCas9	negative selection	2371832
134374399	134374422	5	-	24336569	KBM7	viability	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.09454297606890105	[637]	[1857]	0	hSpCas9	negative selection	2371833
134374441	134374464	5	+	24336569	KBM7	viability	CAGTGGAATGCAGTTATATTTGG	UBE2B	ENSG00000119048	0.26726358671918343	[367]	[1207]	2	hSpCas9	negative selection	2371834
134380757	134380780	5	-	24336569	KBM7	viability	CTAACAGTTGGTGGTTTATTTGG	UBE2B	ENSG00000119048	0.4564189835737636	[232]	[871]	4	hSpCas9	negative selection	2371835
134387008	134387031	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGTGATCTGAG	UBE2B	ENSG00000119048	1.5299201678265226	[5,69]	[1,47]	6	dCas9-VP64	positive selection	2386438
134381040	134381063	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAAGCTCCGCCTCCCGGG	UBE2B	ENSG00000119048	0.20407356943453547	[198,395]	[107,39]	1	dCas9-VP64	positive selection	2401879
134387008	134387031	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGTGATCTGAG	UBE2B	ENSG00000119048	0.46408056547853904	[52,55]	[23,24]	3	dCas9-VP64	positive selection	2481693
134381040	134381063	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAAGCTCCGCCTCCCGGG	UBE2B	ENSG00000119048	4.4236004262517	[85,230]	[22,2123]	9	dCas9-VP64	positive selection	2497134
134371619	134371642	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.4950355482805822	[4,4]	[5,6]	8	hSpCas9	positive selection	3030499
134374385	134374408	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	0.093182370509833	[3,3]	[2,4]	2	hSpCas9	positive selection	3030500
134371619	134371642	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.4192416818368862	[4,4]	[7,2]	7	hSpCas9	positive selection	3098357
134374385	134374408	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	-0.34790515935125116	[3,3]	[2,1]	-5	hSpCas9	positive selection	3098358
134376673	134376696		+	24336571	A375	resistance to PLX after 7 days	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.5308093637897306	[5,4]	[7,7]	9	hSpCas9	positive selection	3153864
134374396	134374419		-	24336571	A375	resistance to PLX after 7 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.34083843085027254	[5,6]	[3,4]	-8	hSpCas9	positive selection	3153865
134374383	134374406		+	24336571	A375	resistance to PLX after 7 days	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.14832966951938248	[10,10]	[10,13]	5	hSpCas9	positive selection	3153866
134376682	134376705		-	24336571	A375	resistance to PLX after 7 days	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.2709139108298106	[9,9]	[7,8]	-7	hSpCas9	positive selection	3153867
134376673	134376696		+	24336571	A375	resistance to PLX after 14 days	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.45811954019968637	[9,7]	[5,4]	4	hSpCas9	positive selection	3211657
134374396	134374419		-	24336571	A375	resistance to PLX after 14 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.06006090909859374	[3,5]	[1,1]	0	hSpCas9	positive selection	3211658
134374383	134374406		+	24336571	A375	resistance to PLX after 14 days	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	4.013091347315549	[6,9]	[56,80]	9	hSpCas9	positive selection	3211659
134376682	134376705		-	24336571	A375	resistance to PLX after 14 days	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.1632581795616765	[8,8]	[3,2]	-2	hSpCas9	positive selection	3211660
134376673	134376696		+	24336571	A375	viability after 7 days	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	-0.07280758105508167	[5]	[5,4]	-1	hSpCas9	negative selection	3269450
134374396	134374419		-	24336571	A375	viability after 7 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.7291053299679244	[11]	[5,6]	-8	hSpCas9	negative selection	3269451
134374383	134374406		+	24336571	A375	viability after 7 days	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.12241233574099505	[10]	[10,10]	1	hSpCas9	negative selection	3269452
134376682	134376705		-	24336571	A375	viability after 7 days	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.6962409512709973	[17]	[9,9]	-7	hSpCas9	negative selection	3269453
134376673	134376696		+	24336571	A375	viability after 14 days	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.5506958323856628	[5]	[9,7]	7	hSpCas9	negative selection	3327243
134374396	134374419		-	24336571	A375	viability after 14 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.142374999459641	[11]	[3,5]	-9	hSpCas9	negative selection	3327244
134374383	134374406		+	24336571	A375	viability after 14 days	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.19669636430040965	[10]	[6,9]	-2	hSpCas9	negative selection	3327245
134376682	134376705		-	24336571	A375	viability after 14 days	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.8533114228081082	[17]	[8,8]	-8	hSpCas9	negative selection	3327246
134388315	134388338	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.6426163673306269	[48,48]	[0,0]	6	hSpCas9	positive selection	3399970
134388349	134388372	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.35000410230377543	[194,194]	[0,0]	-2	hSpCas9	positive selection	3399971
134376682	134376705	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-1.1046175622894063	[328,328]	[0,0]	-7	hSpCas9	positive selection	3399972
134374424	134374447	5	+	26780180	HT29	viability (Avana library 4 designs)	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.909752433897279	[]	[]	3	hSpCas9	negative selection	3469422
134371594	134371617	5	+	26780180	HT29	viability (Avana library 4 designs)	GCATGTCGACCCCGGCCCGGAGG	UBE2B	ENSG00000119048	2.07528872043836	[]	[]	7	hSpCas9	negative selection	3469423
134371618	134371641	5	+	26780180	HT29	viability (Avana library 4 designs)	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.231077427302647	[]	[]	0	hSpCas9	negative selection	3469424
134374384	134374407	5	+	26780180	HT29	viability (Avana library 4 designs)	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	1.95688710683817	[]	[]	7	hSpCas9	negative selection	3469425
134371594	134371617	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGTCGACCCCGGCCCGGAGG	UBE2B	ENSG00000119048	6.27368761744682	[]	[]	9	hSpCas9	negative selection	3574658
134374424	134374447	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-2.91965898454432	[]	[]	-3	hSpCas9	negative selection	3574659
134374384	134374407	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	1.17543056502766	[]	[]	1	hSpCas9	negative selection	3574660
134371618	134371641	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.583445134792341	[]	[]	0	hSpCas9	negative selection	3574661
134371594	134371617	5	+	26780180	A375	viability (Avana lentiGuide)	GCATGTCGACCCCGGCCCGGAGG	UBE2B	ENSG00000119048	2.47493276223707	[]	[]	2	hSpCas9	negative selection	3683317
134374424	134374447	5	+	26780180	A375	viability (Avana lentiGuide)	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	2.48549574160306	[]	[]	2	hSpCas9	negative selection	3683318
134374384	134374407	5	+	26780180	A375	viability (Avana lentiGuide)	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	-2.23995233176509	[]	[]	-4	hSpCas9	negative selection	3683319
134371618	134371641	5	+	26780180	A375	viability (Avana lentiGuide)	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.377089593918479	[]	[]	0	hSpCas9	negative selection	3683320
134371594	134371617	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGTCGACCCCGGCCCGGAGG	UBE2B	ENSG00000119048	0.1596162518905892	[3]	[4,3]	4	hSpCas9	positive selection	3791924
134374424	134374447	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.5023539487713631	[4]	[2,3]	-6	hSpCas9	positive selection	3791925
134374384	134374407	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	0.08159427597726263	[5]	[5,5]	2	hSpCas9	positive selection	3791926
134371618	134371641	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.11202959584069258	[5]	[6,6]	3	hSpCas9	positive selection	3791927
134371594	134371617	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGTCGACCCCGGCCCGGAGG	UBE2B	ENSG00000119048	-0.12733453872271233	[4]	[1,4]	-2	hSpCas9	positive selection	3900531
134374424	134374447	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.8596692709697318	[4]	[3,0]	-8	hSpCas9	positive selection	3900532
134374384	134374407	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACAAGAGGACCCACCTGTGGG	UBE2B	ENSG00000119048	0.11021925084245052	[5]	[5,3]	2	hSpCas9	positive selection	3900533
134371618	134371641	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.3113809493498647	[6]	[6,7]	8	hSpCas9	positive selection	3900534
134380758	134380781	5	+	26780180	A375	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.615752014807968	[]	[]	2	hSpCas9	negative selection	4009631
134374396	134374419	5	-	26780180	A375	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	1.32352705129163	[]	[]	7	hSpCas9	negative selection	4009632
134388315	134388338	5	+	26780180	A375	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.773349464038237	[]	[]	3	hSpCas9	negative selection	4009633
134374383	134374406	5	+	26780180	A375	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	1.32722029068102	[]	[]	7	hSpCas9	negative selection	4009634
134388349	134388372	5	+	26780180	A375	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	1.66342165368072	[]	[]	8	hSpCas9	negative selection	4009635
134376682	134376705	5	-	26780180	A375	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.570087414047775	[]	[]	1	hSpCas9	negative selection	4009636
134380758	134380781	5	+	26780180	HT29	viability (GeCKOv2 library)	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	1.05789633188898	[]	[]	5	hSpCas9	negative selection	4117597
134374396	134374419	5	-	26780180	HT29	viability (GeCKOv2 library)	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	1.40184628593998	[]	[]	7	hSpCas9	negative selection	4117598
134388315	134388338	5	+	26780180	HT29	viability (GeCKOv2 library)	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.36211642829499	[]	[]	7	hSpCas9	negative selection	4117599
134374383	134374406	5	+	26780180	HT29	viability (GeCKOv2 library)	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	1.18577762238915	[]	[]	6	hSpCas9	negative selection	4117600
134388349	134388372	5	+	26780180	HT29	viability (GeCKOv2 library)	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	1.96670511035206	[]	[]	9	hSpCas9	negative selection	4117601
134376682	134376705	5	-	26780180	HT29	viability (GeCKOv2 library)	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.517762327440505	[]	[]	1	hSpCas9	negative selection	4117602
134376673	134376696	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.29914180941534013	[2]	[1,2]	7	hSpCas9	positive selection	4180528
134374396	134374419	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.44901039022008027	[2]	[1,0]	-8	hSpCas9	positive selection	4180529
134374383	134374406	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.4888298379877297	[3]	[1,6]	9	hSpCas9	positive selection	4180530
134376682	134376705	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.057291285446450235	[3]	[1,1]	-1	hSpCas9	positive selection	4180531
134376673	134376696	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.14850919677049576	[3]	[1,5,0,0]	1	hSpCas9	positive selection	4244550
134374396	134374419	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.367208836031609	[1]	[0,3,0,0]	2	hSpCas9	positive selection	4244551
134374383	134374406	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.0440397427591295	[4]	[4,2,1,0]	0	hSpCas9	positive selection	4244552
134376682	134376705	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.1636341413937237	[4]	[1,3,3,0]	1	hSpCas9	positive selection	4244553
134374383	134374406	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.46740200670338056	[3]	[2,4]	8	hSpCas9	positive selection	4306194
134374396	134374419	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.2798392294007288	[2]	[2,0]	-5	hSpCas9	positive selection	4306195
134380758	134380781	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.0971312842281639	[2]	[2,1]	2	hSpCas9	positive selection	4306196
134388315	134388338	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.3797046724391753	[1]	[0,0]	-7	hSpCas9	positive selection	4370443
134388349	134388372	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.07390689390802904	[3]	[3,1]	-1	hSpCas9	positive selection	4370444
134376682	134376705	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.3545124155905424	[3]	[4,3]	7	hSpCas9	positive selection	4370445
134376656	134376678	5	+	27760321	OCIAML3	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.7157673735086056	[207,183]	[203,312]	8	hSpCas9	negative selection	4451693
134376674	134376696	5	+	27760321	OCIAML3	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.1978435846452167	[148,84]	[214,193]	9	hSpCas9	negative selection	4451694
134380766	134380788	5	-	27760321	OCIAML3	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-0.20193277091505646	[47,32]	[21,33]	-2	hSpCas9	negative selection	4451695
134388316	134388338	5	+	27760321	OCIAML3	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.1210469012685578	[453,410]	[623,879]	9	hSpCas9	negative selection	4451696
134388350	134388372	5	+	27760321	OCIAML3	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	1.0191192794104373	[130,118]	[197,197]	9	hSpCas9	negative selection	4451697
134376656	134376678	5	+	27760321	OCIAML2	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.4842684890454785	[207,183]	[160,300]	6	hSpCas9	negative selection	4535156
134376674	134376696	5	+	27760321	OCIAML2	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.01315137220825191	[148,84]	[97,87]	0	hSpCas9	negative selection	4535157
134380766	134380788	5	-	27760321	OCIAML2	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-1.0435108809692277	[47,32]	[16,13]	-7	hSpCas9	negative selection	4535158
134388316	134388338	5	+	27760321	OCIAML2	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.30595896783226184	[453,410]	[404,467]	4	hSpCas9	negative selection	4535159
134388350	134388372	5	+	27760321	OCIAML2	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	1.1141907077312303	[130,118]	[191,253]	9	hSpCas9	negative selection	4535160
134376656	134376678	5	+	27760321	MV411	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	1.589553115354705	[207,183]	[364,423]	9	hSpCas9	negative selection	4618619
134376674	134376696	5	+	27760321	MV411	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.5927246377097548	[148,84]	[120,103]	4	hSpCas9	negative selection	4618620
134380766	134380788	5	-	27760321	MV411	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-4.722875195432629	[47,32]	[0,0]	-9	hSpCas9	negative selection	4618621
134388316	134388338	5	+	27760321	MV411	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.572728380001718	[453,410]	[372,500]	4	hSpCas9	negative selection	4618622
134388350	134388372	5	+	27760321	MV411	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	0.35629188315063565	[130,118]	[15,239]	2	hSpCas9	negative selection	4618623
134376656	134376678	5	+	27760321	HL60	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.6042521204382219	[207,183]	[241,243]	7	hSpCas9	negative selection	4702082
134376674	134376696	5	+	27760321	HL60	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	-0.37568902448452435	[148,84]	[63,80]	-4	hSpCas9	negative selection	4702083
134380766	134380788	5	-	27760321	HL60	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	1.7817206450729717	[47,32]	[108,115]	9	hSpCas9	negative selection	4702084
134388316	134388338	5	+	27760321	HL60	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.2830647906208075	[453,410]	[227,355]	-3	hSpCas9	negative selection	4702085
134388350	134388372	5	+	27760321	HL60	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	0.8039248222431616	[130,118]	[149,207]	8	hSpCas9	negative selection	4702086
134376656	134376678	5	+	27760321	HT1080	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	-0.3813061939256577	[183,143]	[0,103]	-2	hSpCas9	negative selection	4785545
134376674	134376696	5	+	27760321	HT1080	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	-2.5477135154339408	[84,66]	[8,0]	-7	hSpCas9	negative selection	4785546
134380766	134380788	5	-	27760321	HT1080	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-1.9277872697495706	[32,25]	[4,0]	-6	hSpCas9	negative selection	4785547
134388316	134388338	5	+	27760321	HT1080	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.14538161803455013	[410,320]	[180,77]	0	hSpCas9	negative selection	4785548
134388350	134388372	5	+	27760321	HT1080	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.7640282221207413	[118,92]	[0,50]	-3	hSpCas9	negative selection	4785549
134376656	134376678	5	+	27760321	HT29	viability after 7 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.24106033763744028	[183,143]	[232,101,404]	3	hSpCas9	negative selection	4869008
134376674	134376696	5	+	27760321	HT29	viability after 7 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.3687679298163471	[84,66]	[133,97,146]	5	hSpCas9	negative selection	4869009
134380766	134380788	5	-	27760321	HT29	viability after 7 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	0.25656642088769654	[32,25]	[67,51,19]	4	hSpCas9	negative selection	4869010
134388316	134388338	5	+	27760321	HT29	viability after 7 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.3726958931509065	[410,320]	[572,484,758]	6	hSpCas9	negative selection	4869011
134388350	134388372	5	+	27760321	HT29	viability after 7 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-1.1089243137399964	[118,92]	[123,5,67]	-8	hSpCas9	negative selection	4869012
134376656	134376678	5	+	27760321	HT29	viability after 25 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	-0.07273730219688535	[183,143]	[151,154,234]	-1	hSpCas9	negative selection	4952471
134376674	134376696	5	+	27760321	HT29	viability after 25 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.48206330264382724	[84,66]	[117,91,157]	5	hSpCas9	negative selection	4952472
134380766	134380788	5	-	27760321	HT29	viability after 25 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	0.35564364696821116	[32,25]	[8,92,27]	4	hSpCas9	negative selection	4952473
134388316	134388338	5	+	27760321	HT29	viability after 25 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.16182982313968006	[410,320]	[342,363,420]	-2	hSpCas9	negative selection	4952474
134388350	134388372	5	+	27760321	HT29	viability after 25 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.8988032352918276	[118,92]	[72,84,32]	-6	hSpCas9	negative selection	4952475
134376656	134376678	5	+	27760321	HT29	viability after 22 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.6460028311003574	[183,143]	[427,122,335]	7	hSpCas9	negative selection	5035934
134376674	134376696	5	+	27760321	HT29	viability after 22 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.19236653864562525	[84,66]	[103,123,72]	2	hSpCas9	negative selection	5035935
134380766	134380788	5	-	27760321	HT29	viability after 22 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-0.7396913962481522	[32,25]	[2,14,43]	-6	hSpCas9	negative selection	5035936
134388316	134388338	5	+	27760321	HT29	viability after 22 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.2221185249658982	[410,320]	[428,237,419]	-2	hSpCas9	negative selection	5035937
134388350	134388372	5	+	27760321	HT29	viability after 22 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.15826268722370007	[118,92]	[174,114,36]	-2	hSpCas9	negative selection	5035938
134376656	134376678	5	+	27760321	HT29	viability after 19 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.4024470926320409	[183,143]	[268,204,270]	4	hSpCas9	negative selection	5119397
134376674	134376696	5	+	27760321	HT29	viability after 19 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	-0.016144136475497728	[84,66]	[144,109,11]	0	hSpCas9	negative selection	5119398
134380766	134380788	5	-	27760321	HT29	viability after 19 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-3.7401316793788384	[32,25]	[5,0,0]	-9	hSpCas9	negative selection	5119399
134388316	134388338	5	+	27760321	HT29	viability after 19 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.48072865320328145	[410,320]	[351,664,705]	5	hSpCas9	negative selection	5119400
134388350	134388372	5	+	27760321	HT29	viability after 19 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.17739352864936997	[118,92]	[134,149,41]	-2	hSpCas9	negative selection	5119401
134376656	134376678	5	+	27760321	HT29	viability after 16 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.4481776471509221	[183,143]	[183,242,317]	5	hSpCas9	negative selection	5202860
134376674	134376696	5	+	27760321	HT29	viability after 16 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.34457317733028536	[84,66]	[37,125,152]	4	hSpCas9	negative selection	5202861
134380766	134380788	5	-	27760321	HT29	viability after 16 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-0.6436137534956403	[32,25]	[38,24,0]	-6	hSpCas9	negative selection	5202862
134388316	134388338	5	+	27760321	HT29	viability after 16 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.9408379949703557	[410,320]	[302,266,76]	-7	hSpCas9	negative selection	5202863
134388350	134388372	5	+	27760321	HT29	viability after 16 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.48154453709261325	[118,92]	[30,150,65]	-5	hSpCas9	negative selection	5202864
134376656	134376678	5	+	27760321	HT29	viability after 13 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.307213523509702	[183,143]	[286,316,109]	4	hSpCas9	negative selection	5286323
134376674	134376696	5	+	27760321	HT29	viability after 13 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.05725634707859628	[84,66]	[80,112,81]	0	hSpCas9	negative selection	5286324
134380766	134380788	5	-	27760321	HT29	viability after 13 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-0.01947219466004846	[32,25]	[14,62,23]	0	hSpCas9	negative selection	5286325
134388316	134388338	5	+	27760321	HT29	viability after 13 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.0016996417496532128	[410,320]	[616,318,340]	0	hSpCas9	negative selection	5286326
134388350	134388372	5	+	27760321	HT29	viability after 13 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4793281329966803	[118,92]	[198,38,29]	-5	hSpCas9	negative selection	5286327
134376656	134376678	5	+	27760321	HT29	viability after 10 days	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	-0.054525368231066684	[183,143]	[214,297,83]	0	hSpCas9	negative selection	5369786
134376674	134376696	5	+	27760321	HT29	viability after 10 days	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.8073356294067637	[84,66]	[148,204,145]	9	hSpCas9	negative selection	5369787
134380766	134380788	5	-	27760321	HT29	viability after 10 days	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	-0.051963419128817634	[32,25]	[7,54,43]	0	hSpCas9	negative selection	5369788
134388316	134388338	5	+	27760321	HT29	viability after 10 days	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.19818644241139874	[410,320]	[603,392,570]	2	hSpCas9	negative selection	5369789
134388350	134388372	5	+	27760321	HT29	viability after 10 days	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.5076091647721428	[118,92]	[129,90,58]	-6	hSpCas9	negative selection	5369790
134376656	134376678	5	+	27760321	MOLM13	viability	TTCTTGTTTTCAGACCAGAAGG	UBE2B	ENSG00000119048	0.2939567177621123	[207,183]	[76,184]	2	hSpCas9	negative selection	5453249
134376674	134376696	5	+	27760321	MOLM13	viability	AAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.403141596025004	[148,84]	[46,276]	8	hSpCas9	negative selection	5453250
134380766	134380788	5	-	27760321	MOLM13	viability	ATAAAAACCTAACAGTTGGTGG	UBE2B	ENSG00000119048	0.501551146276737	[47,32]	[18,42]	3	hSpCas9	negative selection	5453251
134388316	134388338	5	+	27760321	MOLM13	viability	TCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.5936821029597952	[453,410]	[622,831]	9	hSpCas9	negative selection	5453252
134388350	134388372	5	+	27760321	MOLM13	viability	AGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.5570393487115344	[130,118]	[102,0]	-4	hSpCas9	negative selection	5453253
134371324	134371347	5	+	27661255	K562	viability	GGGAACCGCGCCCCGCTGAAGGG	UBE2B	ENSG00000119048	-2.072381190966911	[1077,1110]	[210,204]	-9	dCas9-KRAB	negative selection	5521043
134371586	134371609	5	+	27661255	K562	viability	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.14530889894424673	[856,822]	[821,674]	5	dCas9-KRAB	negative selection	5521044
134371607	134371630	5	+	27661255	K562	viability	GGCCCGGAGGAGGCTCATGCGGG	UBE2B	ENSG00000119048	-0.006122218381786393	[150,142]	[102,128]	0	dCas9-KRAB	negative selection	5521045
134371769	134371792	5	-	27661255	K562	viability	GTAGGGCCGAGGCTAGGACCCGG	UBE2B	ENSG00000119048	0.2505488392970575	[886,994]	[1062,746]	8	dCas9-KRAB	negative selection	5521046
134371918	134371941	5	-	27661255	K562	viability	GATCGCCTGGGCGAGACGCCGGG	UBE2B	ENSG00000119048	0.07394755653123367	[727,701]	[674,538]	2	dCas9-KRAB	negative selection	5521047
134372054	134372077	5	-	27661255	K562	viability	GCTCCTCGGAGAAGACGGCGGGG	UBE2B	ENSG00000119048	-0.33013880624761316	[359,256]	[207,187]	-7	dCas9-KRAB	negative selection	5521048
134374383	134374406	5	+	27260156	BXPC3	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.26471557762266346	[569]	[603,579,828,889]	6	hSpCas9	negative selection	5578654
134374396	134374419	5	-	27260156	BXPC3	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.09819102830331589	[317]	[310,403,327,382]	2	hSpCas9	negative selection	5578655
134380758	134380781	5	+	27260156	BXPC3	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.11206902460532997	[296]	[280,420,247,396]	2	hSpCas9	negative selection	5578656
134388315	134388338	5	+	27260156	BXPC3	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.27776026040412183	[159]	[137,125,140,147]	-6	hSpCas9	negative selection	5642903
134388349	134388372	5	+	27260156	BXPC3	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.608802874982825	[699]	[411,470,519,527]	-8	hSpCas9	negative selection	5642904
134376682	134376705	5	-	27260156	BXPC3	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.14430426660409768	[966]	[1049,1116,1188,1113]	3	hSpCas9	negative selection	5642905
134374383	134374406	5	+	27260156	A673	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.1861193795227275	[569]	[945,705,805,669]	4	hSpCas9	negative selection	5699905
134374396	134374419	5	-	27260156	A673	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.028709456606713868	[317]	[408,423,395,325]	0	hSpCas9	negative selection	5699906
134380758	134380781	5	+	27260156	A673	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.018168315934968482	[296]	[347,304,405,348]	0	hSpCas9	negative selection	5699907
134388315	134388338	5	+	27260156	A673	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.18332383422474896	[159]	[189,97,225,165]	-4	hSpCas9	negative selection	5764154
134388349	134388372	5	+	27260156	A673	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.45704890761296385	[699]	[763,510,717,465]	-8	hSpCas9	negative selection	5764155
134376682	134376705	5	-	27260156	A673	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.16085254794666026	[966]	[1575,1422,1067,1144]	4	hSpCas9	negative selection	5764156
134374383	134374406	5	+	27260156	A375	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.5255490941799088	[569]	[346,659,397,468]	-6	hSpCas9	negative selection	5821156
134374396	134374419	5	-	27260156	A375	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.0881765382360253	[317]	[130,275,158,148]	-8	hSpCas9	negative selection	5821157
134380758	134380781	5	+	27260156	A375	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.19190633106686633	[296]	[341,608,388,285]	2	hSpCas9	negative selection	5821158
134388315	134388338	5	+	27260156	A375	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.5594203103007312	[159]	[300,345,247,221]	7	hSpCas9	negative selection	5885405
134388349	134388372	5	+	27260156	A375	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.6438517816210372	[699]	[457,809,390,476]	-7	hSpCas9	negative selection	5885406
134376682	134376705	5	-	27260156	A375	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.2771221134590405	[966]	[1370,1834,1189,1162]	4	hSpCas9	negative selection	5885407
134374383	134374406	5	+	27260156	COLO741	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.20385195280186497	[569]	[1087,730,724]	4	hSpCas9	negative selection	5942407
134374396	134374419	5	-	27260156	COLO741	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.10874701802477199	[317]	[515,409,396]	2	hSpCas9	negative selection	5942408
134380758	134380781	5	+	27260156	COLO741	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.3512917474455481	[296]	[586,475,402]	7	hSpCas9	negative selection	5942409
134388315	134388338	5	+	27260156	COLO741	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.3631041969754496	[159]	[170,126,177]	-7	hSpCas9	negative selection	6006656
134388349	134388372	5	+	27260156	COLO741	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4329510668114033	[699]	[776,464,746]	-7	hSpCas9	negative selection	6006657
134376682	134376705	5	-	27260156	COLO741	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.3351225287831725	[966]	[1935,1632,1164]	7	hSpCas9	negative selection	6006658
134374383	134374406	5	+	27260156	CAL120	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.3407094950906349	[569]	[1006,876,827]	5	hSpCas9	negative selection	6063658
134374396	134374419	5	-	27260156	CAL120	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.18858180184277884	[317]	[340,206,489]	-3	hSpCas9	negative selection	6063659
134380758	134380781	5	+	27260156	CAL120	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.7065903596469736	[296]	[697,441,681]	9	hSpCas9	negative selection	6063660
134388315	134388338	5	+	27260156	CAL120	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.2739241460779609	[159]	[46,362,67]	-4	hSpCas9	negative selection	6127907
134388349	134388372	5	+	27260156	CAL120	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.3565062652291882	[699]	[994,517,576]	-5	hSpCas9	negative selection	6127908
134376682	134376705	5	-	27260156	CAL120	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.4029765940559644	[966]	[2379,1408,1110]	6	hSpCas9	negative selection	6127909
134374383	134374406	5	+	27260156	CADOES1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.09613179875839917	[569]	[648,636,556,417]	1	hSpCas9	negative selection	6184909
134374396	134374419	5	-	27260156	CADOES1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5111622643251884	[317]	[215,138,264,209]	-7	hSpCas9	negative selection	6184910
134380758	134380781	5	+	27260156	CADOES1	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.0264972843192961	[296]	[213,327,267,316]	0	hSpCas9	negative selection	6184911
134388315	134388338	5	+	27260156	CADOES1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.0517698426319122	[159]	[163,141,154,155]	0	hSpCas9	negative selection	6249158
134388349	134388372	5	+	27260156	CADOES1	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.37085223902860043	[699]	[450,648,469,441]	-6	hSpCas9	negative selection	6249159
134376682	134376705	5	-	27260156	CADOES1	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.47579934164023485	[966]	[1012,1143,1652,1190]	7	hSpCas9	negative selection	6249160
134374383	134374406	5	+	27260156	EWS502	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.14274329978439587	[569]	[411,564,642,584]	-3	hSpCas9	negative selection	6306160
134374396	134374419	5	-	27260156	EWS502	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5107946494032726	[317]	[248,194,267,232]	-7	hSpCas9	negative selection	6306161
134380758	134380781	5	+	27260156	EWS502	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.23675572864804828	[296]	[361,229,434,468]	4	hSpCas9	negative selection	6306162
134388315	134388338	5	+	27260156	EWS502	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.2400326561093431	[159]	[153,153,109,153]	-4	hSpCas9	negative selection	6370409
134388349	134388372	5	+	27260156	EWS502	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4846414174812883	[699]	[436,558,498,639]	-7	hSpCas9	negative selection	6370410
134376682	134376705	5	-	27260156	EWS502	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.26801754058356186	[966]	[1211,1264,1260,1188]	5	hSpCas9	negative selection	6370411
134374383	134374406	5	+	27260156	EW8	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.24414613468578744	[569]	[574,500,562,547]	4	hSpCas9	negative selection	6427411
134374396	134374419	5	-	27260156	EW8	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.08278560735177809	[317]	[331,236,222,193]	-1	hSpCas9	negative selection	6427412
134380758	134380781	5	+	27260156	EW8	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.14159346396434758	[296]	[437,198,144,126]	-3	hSpCas9	negative selection	6427413
134388315	134388338	5	+	27260156	EW8	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.25473951051839583	[159]	[97,90,162,71]	-5	hSpCas9	negative selection	6491660
134388349	134388372	5	+	27260156	EW8	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.2555574265503761	[699]	[524,531,405,453]	-5	hSpCas9	negative selection	6491661
134376682	134376705	5	-	27260156	EW8	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.49938429112532656	[966]	[1110,1131,912,1304]	8	hSpCas9	negative selection	6491662
134374383	134374406	5	+	27260156	CORL105	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.2423317394330004	[569]	[679,719,920,853]	4	hSpCas9	negative selection	6548662
134374396	134374419	5	-	27260156	CORL105	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5709777640821952	[317]	[282,179,283,262]	-8	hSpCas9	negative selection	6548663
134380758	134380781	5	+	27260156	CORL105	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.3221936493591133	[296]	[543,400,544,270]	6	hSpCas9	negative selection	6548664
134388315	134388338	5	+	27260156	CORL105	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.15756743482500046	[159]	[140,169,232,136]	-3	hSpCas9	negative selection	6612911
134388349	134388372	5	+	27260156	CORL105	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.40858153977130185	[699]	[525,592,697,661]	-6	hSpCas9	negative selection	6612912
134376682	134376705	5	-	27260156	CORL105	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.05558710918099674	[966]	[1157,980,1432,1176]	1	hSpCas9	negative selection	6612913
134374383	134374406	5	+	27260156	HS294T	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.08849755039932461	[569]	[159,279,208,304]	1	hSpCas9	negative selection	6669913
134374396	134374419	5	-	27260156	HS294T	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5236277594056263	[317]	[60,74,85,129]	-6	hSpCas9	negative selection	6669914
134380758	134380781	5	+	27260156	HS294T	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.5258085134354157	[296]	[208,110,154,186]	7	hSpCas9	negative selection	6669915
134388315	134388338	5	+	27260156	HS294T	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.10022844728559832	[159]	[49,111,41,59]	1	hSpCas9	negative selection	6734162
134388349	134388372	5	+	27260156	HS294T	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.6940925113375678	[699]	[155,137,147,240]	-7	hSpCas9	negative selection	6734163
134376682	134376705	5	-	27260156	HS294T	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.14974611738535315	[966]	[372,545,359,370]	2	hSpCas9	negative selection	6734164
134374383	134374406	5	+	27260156	HCC44	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.16057757531130462	[569]	[654,890,772,541]	2	hSpCas9	negative selection	6791164
134374396	134374419	5	-	27260156	HCC44	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5788170887262917	[317]	[197,218,273,273]	-7	hSpCas9	negative selection	6791165
134380758	134380781	5	+	27260156	HCC44	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.4214448486096319	[296]	[345,405,725,364]	7	hSpCas9	negative selection	6791166
134388315	134388338	5	+	27260156	HCC44	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.03561509640872651	[159]	[235,130,272,95]	0	hSpCas9	negative selection	6855413
134388349	134388372	5	+	27260156	HCC44	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.2051713872037536	[699]	[617,700,863,583]	-3	hSpCas9	negative selection	6855414
134376682	134376705	5	-	27260156	HCC44	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.5078931583670017	[966]	[1663,1560,1736,1294]	8	hSpCas9	negative selection	6855415
134374383	134374406	5	+	27260156	G402	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.3101336384162779	[569]	[485,1121,540,1238]	4	hSpCas9	negative selection	6912415
134374396	134374419	5	-	27260156	G402	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.2782506347334683	[317]	[134,49,171,266]	-8	hSpCas9	negative selection	6912416
134380758	134380781	5	+	27260156	G402	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.5455645364105322	[296]	[302,162,383,149]	-6	hSpCas9	negative selection	6912417
134388315	134388338	5	+	27260156	G402	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.3873556409180361	[159]	[315,138,143,26]	-5	hSpCas9	negative selection	6976664
134388349	134388372	5	+	27260156	G402	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.33741433558048833	[699]	[598,1068,386,658]	-4	hSpCas9	negative selection	6976665
134376682	134376705	5	-	27260156	G402	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.4777308897889607	[966]	[1590,1681,1817,1477]	6	hSpCas9	negative selection	6976666
134374383	134374406	5	+	27260156	L33	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.45898269028385735	[569]	[772,314,504,788]	8	hSpCas9	negative selection	7033666
134374396	134374419	5	-	27260156	L33	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.32950253224812787	[317]	[454,184,157,437]	7	hSpCas9	negative selection	7033667
134380758	134380781	5	+	27260156	L33	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.7280766370757085	[296]	[481,205,230,613]	9	hSpCas9	negative selection	7033668
134388315	134388338	5	+	27260156	L33	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.005099417712318477	[159]	[137,69,95,180]	0	hSpCas9	negative selection	7097915
134388349	134388372	5	+	27260156	L33	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.34158857655222974	[699]	[467,232,336,637]	-7	hSpCas9	negative selection	7097916
134376682	134376705	5	-	27260156	L33	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.0033814921697303824	[966]	[1035,349,581,1039]	0	hSpCas9	negative selection	7097917
134374383	134374406	5	+	27260156	K562	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.1922911691974431	[569]	[584,342,287,546]	-2	hSpCas9	negative selection	7154917
134374396	134374419	5	-	27260156	K562	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.2991825915690107	[317]	[209,160,185,340]	-4	hSpCas9	negative selection	7154918
134380758	134380781	5	+	27260156	K562	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.09765333172742252	[296]	[329,301,228,144]	-1	hSpCas9	negative selection	7154919
134388315	134388338	5	+	27260156	K562	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.6799231798330101	[159]	[132,7,99,109]	-7	hSpCas9	negative selection	7219166
134388349	134388372	5	+	27260156	K562	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.34206181745760655	[699]	[241,747,372,577]	-4	hSpCas9	negative selection	7219167
134376682	134376705	5	-	27260156	K562	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.49292108111980437	[966]	[1119,1619,741,1341]	6	hSpCas9	negative selection	7219168
134374383	134374406	5	+	27260156	HT29	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.0027398505689832375	[569]	[712,627,621,782]	0	hSpCas9	negative selection	7276168
134374396	134374419	5	-	27260156	HT29	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.04640219236546095	[317]	[549,277,438,335]	0	hSpCas9	negative selection	7276169
134380758	134380781	5	+	27260156	HT29	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.16901558143396572	[296]	[377,470,421,358]	3	hSpCas9	negative selection	7276170
134388315	134388338	5	+	27260156	HT29	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.1043865144595395	[159]	[316,121,100,186]	-2	hSpCas9	negative selection	7340417
134388349	134388372	5	+	27260156	HT29	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.5538079022511943	[699]	[683,579,617,455]	-7	hSpCas9	negative selection	7340418
134376682	134376705	5	-	27260156	HT29	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.23481230774689754	[966]	[1515,1530,1421,1110]	4	hSpCas9	negative selection	7340419
134374383	134374406	5	+	27260156	MHHES1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.2786928890612727	[569]	[903,1019,905,397]	5	hSpCas9	negative selection	7397419
134374396	134374419	5	-	27260156	MHHES1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.27890782091640176	[317]	[201,470,272,245]	-5	hSpCas9	negative selection	7397420
134380758	134380781	5	+	27260156	MHHES1	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.12236761288493048	[296]	[366,517,355,249]	2	hSpCas9	negative selection	7397421
134388315	134388338	5	+	27260156	MHHES1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.8967192712341074	[159]	[134,116,91,56]	-9	hSpCas9	negative selection	7461668
134388349	134388372	5	+	27260156	MHHES1	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4815081805251865	[699]	[816,471,656,367]	-7	hSpCas9	negative selection	7461669
134376682	134376705	5	-	27260156	MHHES1	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.1629378193755735	[966]	[1316,1206,1349,1030]	3	hSpCas9	negative selection	7461670
134374383	134374406	5	+	27260156	MEWO	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.26386191113178364	[569]	[631,665,620]	6	hSpCas9	negative selection	7518670
134374396	134374419	5	-	27260156	MEWO	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.42441960641739096	[317]	[219,155,288]	-7	hSpCas9	negative selection	7518671
134380758	134380781	5	+	27260156	MEWO	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.18046435109127817	[296]	[403,284,272]	4	hSpCas9	negative selection	7518672
134388315	134388338	5	+	27260156	MEWO	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.3694889093193774	[159]	[207,180,193]	7	hSpCas9	negative selection	7582919
134388349	134388372	5	+	27260156	MEWO	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.22148095496283138	[699]	[673,501,530]	-5	hSpCas9	negative selection	7582920
134376682	134376705	5	-	27260156	MEWO	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.3032213842239091	[966]	[1327,1042,1018]	6	hSpCas9	negative selection	7582921
134374383	134374406	5	+	27260156	LNCAPCLONEFGC	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.13918060900301094	[569]	[427,455,564,441]	-2	hSpCas9	negative selection	7639921
134374396	134374419	5	-	27260156	LNCAPCLONEFGC	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.7955523871507951	[317]	[137,172,200,156]	-8	hSpCas9	negative selection	7639922
134380758	134380781	5	+	27260156	LNCAPCLONEFGC	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.11137957997024794	[296]	[379,220,322,245]	1	hSpCas9	negative selection	7639923
134388315	134388338	5	+	27260156	LNCAPCLONEFGC	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.41940606634871536	[159]	[92,119,74,139]	-6	hSpCas9	negative selection	7704170
134388349	134388372	5	+	27260156	LNCAPCLONEFGC	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.6786066803554097	[699]	[425,336,424,403]	-7	hSpCas9	negative selection	7704171
134376682	134376705	5	-	27260156	LNCAPCLONEFGC	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.40566362380594057	[966]	[1044,957,1359,1322]	6	hSpCas9	negative selection	7704172
134374383	134374406	5	+	27260156	PANC0327	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.27822934356103973	[569]	[762,560,583,566]	4	hSpCas9	negative selection	7761172
134374396	134374419	5	-	27260156	PANC0327	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.044102697313722516	[317]	[193,252,379,334]	0	hSpCas9	negative selection	7761173
134380758	134380781	5	+	27260156	PANC0327	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.15687270258029462	[296]	[328,159,247,226]	-2	hSpCas9	negative selection	7761174
134388315	134388338	5	+	27260156	PANC0327	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.12923347943381525	[159]	[257,187,137,41]	1	hSpCas9	negative selection	7825421
134388349	134388372	5	+	27260156	PANC0327	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.531712519657704	[699]	[654,358,388,344]	-6	hSpCas9	negative selection	7825422
134376682	134376705	5	-	27260156	PANC0327	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.0782245694492738	[966]	[1224,822,825,789]	1	hSpCas9	negative selection	7825423
134374383	134374406	5	+	27260156	NCIH2009	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.06319678427214895	[569]	[895,810,603]	-1	hSpCas9	negative selection	7882423
134374396	134374419	5	-	27260156	NCIH2009	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.8761927335132208	[317]	[433,224,104]	-8	hSpCas9	negative selection	7882424
134380758	134380781	5	+	27260156	NCIH2009	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.8628787109205943	[296]	[1098,631,601]	9	hSpCas9	negative selection	7882425
134388315	134388338	5	+	27260156	NCIH2009	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.622155824611154	[159]	[285,105,71]	-7	hSpCas9	negative selection	7946672
134388349	134388372	5	+	27260156	NCIH2009	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.44844033748455936	[699]	[780,531,851]	-5	hSpCas9	negative selection	7946673
134376682	134376705	5	-	27260156	NCIH2009	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.01925886276099753	[966]	[1656,1268,1237]	0	hSpCas9	negative selection	7946674
134374383	134374406	5	+	27260156	NCIH1373	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.01498215605348091	[569]	[309,693,728,208]	0	hSpCas9	negative selection	8003674
134374396	134374419	5	-	27260156	NCIH1373	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.0300578714710817	[317]	[242,146,149,44]	-8	hSpCas9	negative selection	8003675
134380758	134380781	5	+	27260156	NCIH1373	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	1.0198527562194526	[296]	[829,549,634,189]	9	hSpCas9	negative selection	8003676
134388315	134388338	5	+	27260156	NCIH1373	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-2.139550095654256	[159]	[52,16,19,20]	-9	hSpCas9	negative selection	8067923
134388349	134388372	5	+	27260156	NCIH1373	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.3499035392743619	[699]	[635,468,515,229]	-3	hSpCas9	negative selection	8067924
134376682	134376705	5	-	27260156	NCIH1373	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.13435756159453272	[966]	[1495,758,993,206]	-1	hSpCas9	negative selection	8067925
134374383	134374406	5	+	27260156	PATU8902	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.04269169113770949	[569]	[903,719,775,659]	0	hSpCas9	negative selection	8124925
134374396	134374419	5	-	27260156	PATU8902	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.9999315139578423	[317]	[115,47,375,315]	-7	hSpCas9	negative selection	8124926
134380758	134380781	5	+	27260156	PATU8902	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.16006168369140272	[296]	[491,378,461,517]	1	hSpCas9	negative selection	8124927
134388315	134388338	5	+	27260156	PATU8902	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.5949676462128746	[159]	[150,97,153,188]	-5	hSpCas9	negative selection	8189174
134388349	134388372	5	+	27260156	PATU8902	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-1.3606576845482996	[699]	[300,258,536,377]	-8	hSpCas9	negative selection	8189175
134376682	134376705	5	-	27260156	PATU8902	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.0697819745844741	[966]	[1268,1378,924,2304]	0	hSpCas9	negative selection	8189176
134374383	134374406	5	+	27260156	PANC1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.05588109267004143	[569]	[401,615,487,539]	0	hSpCas9	negative selection	8246176
134374396	134374419	5	-	27260156	PANC1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.2736969335966638	[317]	[231,205,292,173]	-4	hSpCas9	negative selection	8246177
134380758	134380781	5	+	27260156	PANC1	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.37184665108271514	[296]	[434,263,378,236]	6	hSpCas9	negative selection	8246178
134388315	134388338	5	+	27260156	PANC1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.03322889837021448	[159]	[204,138,47,161]	0	hSpCas9	negative selection	8310425
134388349	134388372	5	+	27260156	PANC1	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.38729566048684794	[699]	[473,550,425,406]	-6	hSpCas9	negative selection	8310426
134376682	134376705	5	-	27260156	PANC1	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.5743131406931119	[966]	[953,1601,1425,1056]	8	hSpCas9	negative selection	8310427
134374383	134374406	5	+	27260156	PANC0813	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.1549685900333984	[569]	[799,895,669,625]	2	hSpCas9	negative selection	8367427
134374396	134374419	5	-	27260156	PANC0813	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.2093006575237225	[317]	[415,184,414,286]	-3	hSpCas9	negative selection	8367428
134380758	134380781	5	+	27260156	PANC0813	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.5861194470442455	[296]	[566,463,557,509]	8	hSpCas9	negative selection	8367429
134388315	134388338	5	+	27260156	PANC0813	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.296344895050654	[159]	[118,155,130,199]	-5	hSpCas9	negative selection	8431676
134388349	134388372	5	+	27260156	PANC0813	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4991966865176735	[699]	[729,532,574,505]	-6	hSpCas9	negative selection	8431677
134376682	134376705	5	-	27260156	PANC0813	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.29500789282181095	[966]	[1085,1003,709,915]	-5	hSpCas9	negative selection	8431678
134374383	134374406	5	+	27260156	RDES	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.018763581497948933	[569]	[554,609,713,809]	0	hSpCas9	negative selection	8488678
134374396	134374419	5	-	27260156	RDES	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.2489704097879537	[317]	[288,257,475,195]	-4	hSpCas9	negative selection	8488679
134380758	134380781	5	+	27260156	RDES	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.20051419640609625	[296]	[438,275,439,405]	3	hSpCas9	negative selection	8488680
134388315	134388338	5	+	27260156	RDES	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.32289792983880794	[159]	[116,128,159,193]	-5	hSpCas9	negative selection	8552927
134388349	134388372	5	+	27260156	RDES	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.24049386675403678	[699]	[464,736,752,815]	-4	hSpCas9	negative selection	8552928
134376682	134376705	5	-	27260156	RDES	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.3418607640335616	[966]	[1294,1446,1064,1860]	5	hSpCas9	negative selection	8552929
134374383	134374406	5	+	27260156	PC3	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.017288445348859427	[569]	[415,479,1013,572]	0	hSpCas9	negative selection	8609929
134374396	134374419	5	-	27260156	PC3	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.018350083262623662	[317]	[187,310,579,301]	0	hSpCas9	negative selection	8609930
134380758	134380781	5	+	27260156	PC3	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.6795183684222535	[296]	[192,471,702,719]	9	hSpCas9	negative selection	8609931
134388315	134388338	5	+	27260156	PC3	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.1305300769940787	[159]	[39,278,166,134]	-3	hSpCas9	negative selection	8674178
134388349	134388372	5	+	27260156	PC3	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.47435572370753887	[699]	[269,488,864,589]	-8	hSpCas9	negative selection	8674179
134376682	134376705	5	-	27260156	PC3	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.19212150198353206	[966]	[784,1020,1476,1298]	4	hSpCas9	negative selection	8674180
134374383	134374406	5	+	27260156	PATU8988T	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.6022074997283613	[569]	[945,771,716,910]	8	hSpCas9	negative selection	8731180
134374396	134374419	5	-	27260156	PATU8988T	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.44325055191131996	[317]	[312,236,335,799]	7	hSpCas9	negative selection	8731181
134380758	134380781	5	+	27260156	PATU8988T	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.12063917583266104	[296]	[402,173,263,401]	2	hSpCas9	negative selection	8731182
134388315	134388338	5	+	27260156	PATU8988T	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.00621346775412146	[159]	[70,160,183,203]	0	hSpCas9	negative selection	8795429
134388349	134388372	5	+	27260156	PATU8988T	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.45425791298500434	[699]	[726,374,372,489]	-6	hSpCas9	negative selection	8795430
134376682	134376705	5	-	27260156	PATU8988T	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.03746150004271276	[966]	[706,1086,743,1140]	0	hSpCas9	negative selection	8795431
134374383	134374406	5	+	27260156	T47D	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.05111036034321054	[569]	[633,644,698,779]	1	hSpCas9	negative selection	8852431
134374396	134374419	5	-	27260156	T47D	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.6020016186970872	[317]	[262,254,189,268]	-8	hSpCas9	negative selection	8852432
134380758	134380781	5	+	27260156	T47D	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.321911849067673	[296]	[358,401,486,484]	6	hSpCas9	negative selection	8852433
134388315	134388338	5	+	27260156	T47D	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.5701804549208649	[159]	[58,166,103,169]	-8	hSpCas9	negative selection	8916680
134388349	134388372	5	+	27260156	T47D	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.33358135891622664	[699]	[675,652,642,614]	-6	hSpCas9	negative selection	8916681
134376682	134376705	5	-	27260156	T47D	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.37027414225182764	[966]	[1377,1488,1462,1491]	7	hSpCas9	negative selection	8916682
134374383	134374406	5	+	27260156	SU8686	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.1831233701437533	[569]	[418,585,695,943]	3	hSpCas9	negative selection	8973682
134374396	134374419	5	-	27260156	SU8686	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5554414039807894	[317]	[230,183,241,199]	-7	hSpCas9	negative selection	8973683
134380758	134380781	5	+	27260156	SU8686	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.6217068490947343	[296]	[466,370,504,480]	9	hSpCas9	negative selection	8973684
134388315	134388338	5	+	27260156	SU8686	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.6468300568918972	[159]	[68,100,95,149]	-7	hSpCas9	negative selection	9037931
134388349	134388372	5	+	27260156	SU8686	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.6416767650677162	[699]	[394,404,461,540]	-7	hSpCas9	negative selection	9037932
134376682	134376705	5	-	27260156	SU8686	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	-0.13274190132713304	[966]	[858,859,768,1028]	-2	hSpCas9	negative selection	9037933
134374383	134374406	5	+	27260156	SKES1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.23175201995629097	[569]	[712,869,745,396]	5	hSpCas9	negative selection	9094933
134374396	134374419	5	-	27260156	SKES1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.06486573515049077	[317]	[386,379,228,242]	-1	hSpCas9	negative selection	9094934
134380758	134380781	5	+	27260156	SKES1	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.07980103443896369	[296]	[310,330,314,182]	-2	hSpCas9	negative selection	9094935
134388315	134388338	5	+	27260156	SKES1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.1912608527947639	[159]	[180,186,133,74]	-4	hSpCas9	negative selection	9159182
134388349	134388372	5	+	27260156	SKES1	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.34259957976370203	[699]	[590,620,519,486]	-6	hSpCas9	negative selection	9159183
134376682	134376705	5	-	27260156	SKES1	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.2247219365925781	[966]	[1237,1239,1115,952]	5	hSpCas9	negative selection	9159184
134374383	134374406	5	+	27260156	TOV112D	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.10109991917280231	[569]	[459,826,354,551]	-2	hSpCas9	negative selection	9216184
134374396	134374419	5	-	27260156	TOV112D	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.334994043883664	[317]	[630,376,263,348]	6	hSpCas9	negative selection	9216185
134380758	134380781	5	+	27260156	TOV112D	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.4328850409312013	[296]	[349,569,369,353]	7	hSpCas9	negative selection	9216186
134388315	134388338	5	+	27260156	TOV112D	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.06179668555614204	[159]	[169,205,115,185]	1	hSpCas9	negative selection	9280433
134388349	134388372	5	+	27260156	TOV112D	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.27368936386272064	[699]	[375,1046,356,634]	-5	hSpCas9	negative selection	9280434
134376682	134376705	5	-	27260156	TOV112D	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.26713684029324414	[966]	[1228,1418,992,1088]	5	hSpCas9	negative selection	9280435
134374383	134374406	5	+	27260156	TC71	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.236208548578349	[569]	[721,710,660,790]	6	hSpCas9	negative selection	9337435
134374396	134374419	5	-	27260156	TC71	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.35438069761526814	[317]	[448,449,405,438]	8	hSpCas9	negative selection	9337436
134380758	134380781	5	+	27260156	TC71	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	-0.2581393949157278	[296]	[202,223,337,300]	-6	hSpCas9	negative selection	9337437
134388315	134388338	5	+	27260156	TC71	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.023878239167500537	[159]	[112,206,170,185]	0	hSpCas9	negative selection	9401684
134388349	134388372	5	+	27260156	TC71	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.43763164671060106	[699]	[433,606,556,624]	-8	hSpCas9	negative selection	9401685
134376682	134376705	5	-	27260156	TC71	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.28718769318642745	[966]	[1430,1207,1197,1217]	7	hSpCas9	negative selection	9401686
134374383	134374406	5	+	27260156	TC32	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.056936808914562376	[569]	[643,362,598,664]	1	hSpCas9	negative selection	9458686
134374396	134374419	5	-	27260156	TC32	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.6704274735295298	[317]	[226,71,235,256]	-8	hSpCas9	negative selection	9458687
134380758	134380781	5	+	27260156	TC32	viability	CAAATAAACCACCAACTGTTAGG	UBE2B	ENSG00000119048	0.26962566085215545	[296]	[360,188,402,443]	5	hSpCas9	negative selection	9458688
134388315	134388338	5	+	27260156	TC32	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.44985068201796063	[159]	[73,73,216,105]	-7	hSpCas9	negative selection	9522935
134388349	134388372	5	+	27260156	TC32	viability	TAGATATCCTTCAGAATCGATGG	UBE2B	ENSG00000119048	-0.4708794132884532	[699]	[542,274,547,590]	-7	hSpCas9	negative selection	9522936
134376682	134376705	5	-	27260156	TC32	viability	TATGACTTACCATCTTCAAAAGG	UBE2B	ENSG00000119048	0.22578175608227147	[966]	[756,1034,1346,1148]	4	hSpCas9	negative selection	9522937
134371586	134371609	5	+	27869803	HPAFII	viability after 27 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.9622366278738733	[188]	[74,30,NaN]	-6	hSpCas9	negative selection	9589965
134374379	134374402	5	-	27869803	HPAFII	viability after 27 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.387255381056564	[391]	[196,329,NaN]	3	hSpCas9	negative selection	9589966
134374396	134374419	5	-	27869803	HPAFII	viability after 27 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.7975469584273381	[365]	[322,343,NaN]	6	hSpCas9	negative selection	9589967
134374399	134374422	5	-	27869803	HPAFII	viability after 27 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	2.003723309497399	[51]	[53,155,NaN]	9	hSpCas9	negative selection	9589968
134390319	134390342	5	+	27869803	HPAFII	viability after 27 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.6763041685686806	[570]	[620,361,NaN]	5	hSpCas9	negative selection	9589969
134371586	134371609	5	+	27869803	HPAFII	viability after 15 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.047455076615035	[188]	[191,39,NaN]	-8	hSpCas9	negative selection	9672414
134374379	134374402	5	-	27869803	HPAFII	viability after 15 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.15804973270007472	[391]	[511,443,NaN]	1	hSpCas9	negative selection	9672415
134374396	134374419	5	-	27869803	HPAFII	viability after 15 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.44720901317300965	[365]	[658,459,NaN]	5	hSpCas9	negative selection	9672416
134374399	134374422	5	-	27869803	HPAFII	viability after 15 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.8974465356833663	[51]	[129,87,NaN]	8	hSpCas9	negative selection	9672417
134390319	134390342	5	+	27869803	HPAFII	viability after 15 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.6926720875099852	[570]	[1449,706,NaN]	7	hSpCas9	negative selection	9672418
134371586	134371609	5	+	27869803	ASPC1	viability after 36 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	0.1068206924182536	[473]	[142,157,216]	1	hSpCas9	negative selection	9754863
134374379	134374402	5	-	27869803	ASPC1	viability after 36 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.38943446625253575	[726]	[345,148,464]	4	hSpCas9	negative selection	9754864
134374396	134374419	5	-	27869803	ASPC1	viability after 36 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.791195341412769	[862]	[1155,288,254]	7	hSpCas9	negative selection	9754865
134374399	134374422	5	-	27869803	ASPC1	viability after 36 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	1.678366099710788	[118]	[361,94,0]	9	hSpCas9	negative selection	9754866
134390319	134390342	5	+	27869803	ASPC1	viability after 36 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.294844812956075	[1614]	[320,1021,681]	3	hSpCas9	negative selection	9754867
134371586	134371609	5	+	27869803	PATU8988S	viability after 35 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.0412903299746068	[297]	[174,57,NaN]	0	hSpCas9	negative selection	9837312
134374379	134374402	5	-	27869803	PATU8988S	viability after 35 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	1.0588830353870078	[768]	[747,541,NaN]	9	hSpCas9	negative selection	9837313
134374396	134374419	5	-	27869803	PATU8988S	viability after 35 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.018150302832679488	[835]	[327,336,NaN]	0	hSpCas9	negative selection	9837314
134374399	134374422	5	-	27869803	PATU8988S	viability after 35 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.6888138867512816	[167]	[138,78,NaN]	7	hSpCas9	negative selection	9837315
134390319	134390342	5	+	27869803	PATU8988S	viability after 35 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.38151033116628685	[1262]	[728,595,NaN]	4	hSpCas9	negative selection	9837316
134371586	134371609	5	+	27869803	PATU8988S	viability after 31 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.8060565739991572	[297]	[74,58,NaN]	-7	hSpCas9	negative selection	9919761
134374379	134374402	5	-	27869803	PATU8988S	viability after 31 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.7706010070843093	[768]	[479,577,NaN]	8	hSpCas9	negative selection	9919762
134374396	134374419	5	-	27869803	PATU8988S	viability after 31 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.36253088141147716	[835]	[253,265,NaN]	-4	hSpCas9	negative selection	9919763
134374399	134374422	5	-	27869803	PATU8988S	viability after 31 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	0.8672181180338715	[167]	[108,138,NaN]	8	hSpCas9	negative selection	9919764
134390319	134390342	5	+	27869803	PATU8988S	viability after 31 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.30908368468881764	[1262]	[509,768,NaN]	4	hSpCas9	negative selection	9919765
134371586	134371609	5	+	27869803	HPAFII	viability after 35 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-0.7937228043659542	[188]	[89,15,NaN]	-5	hSpCas9	negative selection	10002210
134374379	134374402	5	-	27869803	HPAFII	viability after 35 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	-0.040016532088664625	[391]	[113,281,NaN]	0	hSpCas9	negative selection	10002211
134374396	134374419	5	-	27869803	HPAFII	viability after 35 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.42682570040192114	[365]	[162,345,NaN]	2	hSpCas9	negative selection	10002212
134374399	134374422	5	-	27869803	HPAFII	viability after 35 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	1.6664794995723207	[51]	[36,135,NaN]	9	hSpCas9	negative selection	10002213
134390319	134390342	5	+	27869803	HPAFII	viability after 35 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.9637772396553552	[570]	[631,486,NaN]	6	hSpCas9	negative selection	10002214
134371586	134371609	5	+	27869803	HPAFII	viability after 31 days	GCTGCGGAGCATGTCGACCCCGG	UBE2B	ENSG00000119048	-1.1802144251006408	[188]	[75,14,NaN]	-6	hSpCas9	negative selection	10084659
134374379	134374402	5	-	27869803	HPAFII	viability after 31 days	AGGTGGGTCCTCTTGTAACCTGG	UBE2B	ENSG00000119048	0.29757458637540557	[391]	[133,418,NaN]	2	hSpCas9	negative selection	10084660
134374396	134374419	5	-	27869803	HPAFII	viability after 31 days	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.4295149748154503	[365]	[167,394,NaN]	3	hSpCas9	negative selection	10084661
134374399	134374422	5	-	27869803	HPAFII	viability after 31 days	GGTGCGCCACTGACACCCACAGG	UBE2B	ENSG00000119048	1.4061276368041629	[51]	[17,141,NaN]	9	hSpCas9	negative selection	10084662
134390319	134390342	5	+	27869803	HPAFII	viability after 31 days	CGGCCATTGTTGAACAAAGCTGG	UBE2B	ENSG00000119048	0.7429399222462538	[570]	[531,540,NaN]	5	hSpCas9	negative selection	10084663
134374396	134374419	5	-	28162770	P31FUJ	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.02635132694695214	[220]	[254]	0	hSpCas9	negative selection	10260183
134388356	134388379	5	-	28162770	P31FUJ	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.38002367608282084	[734]	[1123]	4	hSpCas9	negative selection	10260184
134371591	134371614	5	+	28162770	P31FUJ	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.4746443028317725	[78]	[128]	5	hSpCas9	negative selection	10260185
134374424	134374447	5	+	28162770	P31FUJ	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.9988234967001064	[88]	[208]	9	hSpCas9	negative selection	10260186
134374383	134374406	5	+	28162770	P31FUJ	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.9702896609631331	[300]	[692]	9	hSpCas9	negative selection	10260187
134371603	134371626	5	-	28162770	P31FUJ	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5499875720466934	[439]	[756]	6	hSpCas9	negative selection	10260188
134376673	134376696	5	+	28162770	P31FUJ	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.6416669135017625	[323]	[593]	7	hSpCas9	negative selection	10260189
134374371	134374394	5	+	28162770	P31FUJ	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.06070283173772918	[220]	[248]	0	hSpCas9	negative selection	10260190
134388315	134388338	5	+	28162770	P31FUJ	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.11710965209938196	[724]	[923]	1	hSpCas9	negative selection	10260191
134371618	134371641	5	+	28162770	P31FUJ	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	-0.010409783077930723	[401]	[468]	0	hSpCas9	negative selection	10260192
134374396	134374419	5	-	28162770	TF1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10429549
134388356	134388379	5	-	28162770	TF1	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	NaN	[NaN]	[996]	1	hSpCas9	negative selection	10429550
134371591	134371614	5	+	28162770	TF1	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10429551
134374424	134374447	5	+	28162770	TF1	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10429552
134374383	134374406	5	+	28162770	TF1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10429553
134371603	134371626	5	-	28162770	TF1	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10429554
134376673	134376696	5	+	28162770	TF1	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	NaN	[NaN]	[386]	1	hSpCas9	negative selection	10429555
134374371	134374394	5	+	28162770	TF1	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10429556
134388315	134388338	5	+	28162770	TF1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	NaN	[NaN]	[603]	1	hSpCas9	negative selection	10429557
134371618	134371641	5	+	28162770	TF1	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10429558
134374396	134374419	5	-	28162770	SKM1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.08488889758651305	[47]	[89]	0	hSpCas9	negative selection	10598915
134388356	134388379	5	-	28162770	SKM1	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.6082382079005086	[176]	[476]	6	hSpCas9	negative selection	10598916
134371591	134371614	5	+	28162770	SKM1	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10598917
134374424	134374447	5	+	28162770	SKM1	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.6024961305059044	[18]	[50]	6	hSpCas9	negative selection	10598918
134374383	134374406	5	+	28162770	SKM1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.2206426393864882	[99]	[205]	2	hSpCas9	negative selection	10598919
134371603	134371626	5	-	28162770	SKM1	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5136013337624332	[125]	[317]	5	hSpCas9	negative selection	10598920
134376673	134376696	5	+	28162770	SKM1	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.4510167963844104	[83]	[202]	4	hSpCas9	negative selection	10598921
134374371	134374394	5	+	28162770	SKM1	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-1.1439297929093677	[39]	[31]	-7	hSpCas9	negative selection	10598922
134388315	134388338	5	+	28162770	SKM1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.1779983019779945	[176]	[353]	1	hSpCas9	negative selection	10598923
134371618	134371641	5	+	28162770	SKM1	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.030152834006600515	[76]	[138]	0	hSpCas9	negative selection	10598924
134374396	134374419	5	-	28162770	SKM1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.08488889758651305	[47]	[89]	0	hSpCas9	negative selection	10768281
134388356	134388379	5	-	28162770	SKM1	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.6082382079005086	[176]	[476]	6	hSpCas9	negative selection	10768282
134371591	134371614	5	+	28162770	SKM1	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10768283
134374424	134374447	5	+	28162770	SKM1	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.6024961305059044	[18]	[50]	6	hSpCas9	negative selection	10768284
134374383	134374406	5	+	28162770	SKM1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.2206426393864882	[99]	[205]	2	hSpCas9	negative selection	10768285
134371603	134371626	5	-	28162770	SKM1	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5136013337624332	[125]	[317]	5	hSpCas9	negative selection	10768286
134376673	134376696	5	+	28162770	SKM1	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.4510167963844104	[83]	[202]	4	hSpCas9	negative selection	10768287
134374371	134374394	5	+	28162770	SKM1	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-1.1439297929093677	[39]	[31]	-7	hSpCas9	negative selection	10768288
134388315	134388338	5	+	28162770	SKM1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.1779983019779945	[176]	[353]	1	hSpCas9	negative selection	10768289
134371618	134371641	5	+	28162770	SKM1	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.030152834006600515	[76]	[138]	0	hSpCas9	negative selection	10768290
134374396	134374419	5	-	28162770	PL21	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.5973675216119368	[218]	[62]	-4	hSpCas9	negative selection	10937647
134388356	134388379	5	-	28162770	PL21	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	1.0103853880915055	[640]	[561]	8	hSpCas9	negative selection	10937648
134371591	134371614	5	+	28162770	PL21	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-3.1217884803980427	[79]	[3]	-9	hSpCas9	negative selection	10937649
134374424	134374447	5	+	28162770	PL21	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.17837200876440984	[103]	[39]	-1	hSpCas9	negative selection	10937650
134374383	134374406	5	+	28162770	PL21	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.1281897726103054	[369]	[175]	1	hSpCas9	negative selection	10937651
134371603	134371626	5	-	28162770	PL21	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5717378525032665	[353]	[228]	5	hSpCas9	negative selection	10937652
134376673	134376696	5	+	28162770	PL21	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.4158683055447573	[216]	[125]	3	hSpCas9	negative selection	10937653
134374371	134374394	5	+	28162770	PL21	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.7657367903435452	[149]	[110]	6	hSpCas9	negative selection	10937654
134388315	134388338	5	+	28162770	PL21	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.14954917359865605	[445]	[174]	-1	hSpCas9	negative selection	10937655
134371618	134371641	5	+	28162770	PL21	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.8005321557800824	[247]	[187]	7	hSpCas9	negative selection	10937656
134374396	134374419	5	-	28162770	P31FUJ	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.02635132694695214	[220]	[254]	0	hSpCas9	negative selection	11107013
134388356	134388379	5	-	28162770	P31FUJ	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.38002367608282084	[734]	[1123]	4	hSpCas9	negative selection	11107014
134371591	134371614	5	+	28162770	P31FUJ	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.4746443028317725	[78]	[128]	5	hSpCas9	negative selection	11107015
134374424	134374447	5	+	28162770	P31FUJ	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.9988234967001064	[88]	[208]	9	hSpCas9	negative selection	11107016
134374383	134374406	5	+	28162770	P31FUJ	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.9702896609631331	[300]	[692]	9	hSpCas9	negative selection	11107017
134371603	134371626	5	-	28162770	P31FUJ	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5499875720466934	[439]	[756]	6	hSpCas9	negative selection	11107018
134376673	134376696	5	+	28162770	P31FUJ	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.6416669135017625	[323]	[593]	7	hSpCas9	negative selection	11107019
134374371	134374394	5	+	28162770	P31FUJ	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.06070283173772918	[220]	[248]	0	hSpCas9	negative selection	11107020
134388315	134388338	5	+	28162770	P31FUJ	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.11710965209938196	[724]	[923]	1	hSpCas9	negative selection	11107021
134371618	134371641	5	+	28162770	P31FUJ	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	-0.010409783077930723	[401]	[468]	0	hSpCas9	negative selection	11107022
134374396	134374419	5	-	28162770	OCIAML5	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.7100860469490732	[84]	[250]	6	hSpCas9	negative selection	11276379
134388356	134388379	5	-	28162770	OCIAML5	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.14229789446657026	[512]	[1021]	1	hSpCas9	negative selection	11276380
134371591	134371614	5	+	28162770	OCIAML5	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	1.0162894233255322	[42]	[156]	8	hSpCas9	negative selection	11276381
134374424	134374447	5	+	28162770	OCIAML5	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.3889415286397979	[43]	[103]	3	hSpCas9	negative selection	11276382
134374383	134374406	5	+	28162770	OCIAML5	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.34014284497607294	[206]	[472]	3	hSpCas9	negative selection	11276383
134371603	134371626	5	-	28162770	OCIAML5	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.4014745490431151	[215]	[514]	3	hSpCas9	negative selection	11276384
134376673	134376696	5	+	28162770	OCIAML5	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.1556278209260036	[186]	[751]	8	hSpCas9	negative selection	11276385
134374371	134374394	5	+	28162770	OCIAML5	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.02894433294807615	[129]	[229]	0	hSpCas9	negative selection	11276386
134388315	134388338	5	+	28162770	OCIAML5	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.9475388515886727	[319]	[1113]	7	hSpCas9	negative selection	11276387
134371618	134371641	5	+	28162770	OCIAML5	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.43314974566684417	[198]	[484]	4	hSpCas9	negative selection	11276388
134374396	134374419	5	-	28162770	EOL1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.27247107499084156	[428]	[272]	2	hSpCas9	negative selection	11445745
134388356	134388379	5	-	28162770	EOL1	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	-0.18334986005904463	[790]	[366]	-1	hSpCas9	negative selection	11445746
134371591	134371614	5	+	28162770	EOL1	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.2326700669328664	[146]	[90]	2	hSpCas9	negative selection	11445747
134374424	134374447	5	+	28162770	EOL1	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.4787480185210036	[157]	[115]	4	hSpCas9	negative selection	11445748
134374383	134374406	5	+	28162770	EOL1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.06802679270904588	[678]	[374]	0	hSpCas9	negative selection	11445749
134371603	134371626	5	-	28162770	EOL1	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.44108513128080684	[733]	[524]	4	hSpCas9	negative selection	11445750
134376673	134376696	5	+	28162770	EOL1	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.4225496747508237	[358]	[506]	9	hSpCas9	negative selection	11445751
134374371	134374394	5	+	28162770	EOL1	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.7220549076717916	[167]	[145]	6	hSpCas9	negative selection	11445752
134388315	134388338	5	+	28162770	EOL1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.20856345016182	[693]	[844]	8	hSpCas9	negative selection	11445753
134371618	134371641	5	+	28162770	EOL1	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.10724006908672468	[399]	[226]	1	hSpCas9	negative selection	11445754
134374396	134374419	5	-	28162770	MOLM13	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.22996717558251079	[278]	[171]	-1	hSpCas9	negative selection	11615111
134388356	134388379	5	-	28162770	MOLM13	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.5338236517293553	[1111]	[1163]	4	hSpCas9	negative selection	11615112
134371591	134371614	5	+	28162770	MOLM13	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.967962984679222	[139]	[197]	7	hSpCas9	negative selection	11615113
134374424	134374447	5	+	28162770	MOLM13	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.16599903989376152	[142]	[115]	1	hSpCas9	negative selection	11615114
134374383	134374406	5	+	28162770	MOLM13	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.865731265560901	[421]	[555]	6	hSpCas9	negative selection	11615115
134371603	134371626	5	-	28162770	MOLM13	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	1.1216253020459623	[552]	[869]	8	hSpCas9	negative selection	11615116
134376673	134376696	5	+	28162770	MOLM13	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.6458876835225734	[395]	[447]	5	hSpCas9	negative selection	11615117
134374371	134374394	5	+	28162770	MOLM13	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.3913648893845854	[270]	[256]	3	hSpCas9	negative selection	11615118
134388315	134388338	5	+	28162770	MOLM13	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	1.0708741524627694	[768]	[1167]	7	hSpCas9	negative selection	11615119
134371618	134371641	5	+	28162770	MOLM13	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	1.582519200971935	[392]	[850]	9	hSpCas9	negative selection	11615120
134374396	134374419	5	-	28162770	HEL	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.6445431200801144	[287]	[58]	-7	hSpCas9	negative selection	11784477
134388356	134388379	5	-	28162770	HEL	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.7563624434361933	[658]	[712]	6	hSpCas9	negative selection	11784478
134371591	134371614	5	+	28162770	HEL	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-0.6435653531562839	[99]	[40]	-4	hSpCas9	negative selection	11784479
134374424	134374447	5	+	28162770	HEL	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.652586617956704	[145]	[146]	5	hSpCas9	negative selection	11784480
134374383	134374406	5	+	28162770	HEL	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.23019088474721094	[385]	[289]	2	hSpCas9	negative selection	11784481
134371603	134371626	5	-	28162770	HEL	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.5896274955407945	[497]	[479]	5	hSpCas9	negative selection	11784482
134376673	134376696	5	+	28162770	HEL	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	-0.3774390499372734	[287]	[141]	-3	hSpCas9	negative selection	11784483
134374371	134374394	5	+	28162770	HEL	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-1.5754413380491765	[227]	[48]	-7	hSpCas9	negative selection	11784484
134388315	134388338	5	+	28162770	HEL	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	-0.2738451598120055	[671]	[355]	-2	hSpCas9	negative selection	11784485
134371618	134371641	5	+	28162770	HEL	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	-0.4986170172451847	[374]	[169]	-3	hSpCas9	negative selection	11784486
134374396	134374419	5	-	28162770	MV411	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-1.2119940678545218	[197]	[71]	-7	hSpCas9	negative selection	11953843
134388356	134388379	5	-	28162770	MV411	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.6496809378455666	[537]	[710]	6	hSpCas9	negative selection	11953844
134371591	134371614	5	+	28162770	MV411	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	-0.19616910069283944	[67]	[49]	-1	hSpCas9	negative selection	11953845
134374424	134374447	5	+	28162770	MV411	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.15057601153018618	[76]	[71]	1	hSpCas9	negative selection	11953846
134374383	134374406	5	+	28162770	MV411	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.979287199726661	[338]	[562]	8	hSpCas9	negative selection	11953847
134371603	134371626	5	-	28162770	MV411	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.39499473919663286	[454]	[503]	3	hSpCas9	negative selection	11953848
134376673	134376696	5	+	28162770	MV411	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.7472554702586385	[284]	[402]	6	hSpCas9	negative selection	11953849
134374371	134374394	5	+	28162770	MV411	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.44152460289907763	[124]	[142]	4	hSpCas9	negative selection	11953850
134388315	134388338	5	+	28162770	MV411	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.30824979260432994	[510]	[532]	2	hSpCas9	negative selection	11953851
134371618	134371641	5	+	28162770	MV411	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.836336466063102	[243]	[366]	7	hSpCas9	negative selection	11953852
134374396	134374419	5	-	28162770	MONOMAC1	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	0.43170734568951574	[118]	[183]	4	hSpCas9	negative selection	12123209
134388356	134388379	5	-	28162770	MONOMAC1	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.434507789870471	[385]	[597]	4	hSpCas9	negative selection	12123210
134371591	134371614	5	+	28162770	MONOMAC1	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	2.267631419943891	[49]	[275]	9	hSpCas9	negative selection	12123211
134374424	134374447	5	+	28162770	MONOMAC1	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.25843739172369695	[71]	[68]	-2	hSpCas9	negative selection	12123212
134374383	134374406	5	+	28162770	MONOMAC1	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.5839533709986505	[212]	[365]	6	hSpCas9	negative selection	12123213
134371603	134371626	5	-	28162770	MONOMAC1	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.46311315005582165	[242]	[383]	4	hSpCas9	negative selection	12123214
134376673	134376696	5	+	28162770	MONOMAC1	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	1.0238720831015637	[138]	[323]	8	hSpCas9	negative selection	12123215
134374371	134374394	5	+	28162770	MONOMAC1	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.016366791049639673	[68]	[79]	0	hSpCas9	negative selection	12123216
134388315	134388338	5	+	28162770	MONOMAC1	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.1369640801283838	[356]	[449]	1	hSpCas9	negative selection	12123217
134371618	134371641	5	+	28162770	MONOMAC1	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	-0.009666711157831936	[136]	[155]	0	hSpCas9	negative selection	12123218
134374396	134374419	5	-	28162770	OCIAML2	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.511271809739507	[35]	[139]	-4	hSpCas9	negative selection	12292575
134388356	134388379	5	-	28162770	OCIAML2	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.5048874895584952	[103]	[817]	5	hSpCas9	negative selection	12292576
134371591	134371614	5	+	28162770	OCIAML2	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.276604104377872	[13]	[93]	2	hSpCas9	negative selection	12292577
134374424	134374447	5	+	28162770	OCIAML2	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	0.8305397094784037	[20]	[206]	7	hSpCas9	negative selection	12292578
134374383	134374406	5	+	28162770	OCIAML2	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	0.4185420445454593	[70]	[525]	4	hSpCas9	negative selection	12292579
134371603	134371626	5	-	28162770	OCIAML2	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.7980562483682215	[68]	[664]	7	hSpCas9	negative selection	12292580
134376673	134376696	5	+	28162770	OCIAML2	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.3485667094599594	[51]	[366]	3	hSpCas9	negative selection	12292581
134374371	134374394	5	+	28162770	OCIAML2	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	0.7620309315481136	[24]	[234]	7	hSpCas9	negative selection	12292582
134388315	134388338	5	+	28162770	OCIAML2	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.606879541978754	[76]	[649]	6	hSpCas9	negative selection	12292583
134371618	134371641	5	+	28162770	OCIAML2	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	0.630908201219901	[47]	[411]	6	hSpCas9	negative selection	12292584
134374396	134374419	5	-	28162770	OCIAML3	viability	GCGCCACTGACACCCACAGGTGG	UBE2B	ENSG00000119048	-0.3122366719087835	[50]	[123]	-2	hSpCas9	negative selection	12461941
134388356	134388379	5	-	28162770	OCIAML3	viability	TTGGACTCCATCGATTCTGAAGG	UBE2B	ENSG00000119048	0.07341702058896571	[169]	[539]	0	hSpCas9	negative selection	12461942
134371591	134371614	5	+	28162770	OCIAML3	viability	GGAGCATGTCGACCCCGGCCCGG	UBE2B	ENSG00000119048	0.06310464615282829	[25]	[81]	0	hSpCas9	negative selection	12461943
134374424	134374447	5	+	28162770	OCIAML3	viability	CTGAAAACAACATCATGCAGTGG	UBE2B	ENSG00000119048	-0.4420045468791133	[26]	[59]	-3	hSpCas9	negative selection	12461944
134374383	134374406	5	+	28162770	OCIAML3	viability	GTTACAAGAGGACCCACCTGTGG	UBE2B	ENSG00000119048	-0.009045139603007124	[92]	[278]	0	hSpCas9	negative selection	12461945
134371603	134371626	5	-	28162770	OCIAML3	viability	CATGAGCCTCCTCCGGGCCGGGG	UBE2B	ENSG00000119048	0.9860393699828766	[97]	[585]	8	hSpCas9	negative selection	12461946
134376673	134376696	5	+	28162770	OCIAML3	viability	GAAGGGACACCTTTTGAAGATGG	UBE2B	ENSG00000119048	0.3849307441480072	[68]	[271]	3	hSpCas9	negative selection	12461947
134374371	134374394	5	+	28162770	OCIAML3	viability	CTGGATTTCCAGGTTACAAGAGG	UBE2B	ENSG00000119048	-0.9391431263728507	[46]	[73]	-6	hSpCas9	negative selection	12461948
134388315	134388338	5	+	28162770	OCIAML3	viability	GTCTTTGCAGTGTATGCTGATGG	UBE2B	ENSG00000119048	0.22274597973569032	[152]	[538]	2	hSpCas9	negative selection	12461949
134371618	134371641	5	+	28162770	OCIAML3	viability	GGCTCATGCGGGATTTCAAGCGG	UBE2B	ENSG00000119048	-0.1494788443359203	[114]	[312]	-1	hSpCas9	negative selection	12461950