Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 7337
• Symbol: UBE3A
• Description: ubiquitin protein ligase E3A

DataSource: http://genomecrispr.dkfz.de/#!/results/UBE3A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
25370882	25370905	15	+	26472758	Jiyoye	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.5928246184941267	[129]	[64]	-4	hSpCas9	negative selection	176542
25375504	25375527	15	+	26472758	Jiyoye	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.9042857143304203	[205]	[82]	-6	hSpCas9	negative selection	176543
25360442	25360465	15	-	26472758	Jiyoye	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.5731958117451941	[145]	[73]	-4	hSpCas9	negative selection	176544
25371539	25371562	15	-	26472758	Jiyoye	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.26782579859056543	[390]	[354]	2	hSpCas9	negative selection	176545
25375708	25375731	15	-	26472758	Jiyoye	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.10978947088130253	[101]	[82]	0	hSpCas9	negative selection	176546
25371025	25371048	15	-	26472758	Jiyoye	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	-0.2540227050423681	[203]	[128]	-2	hSpCas9	negative selection	176547
25370854	25370877	15	+	26472758	Jiyoye	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-1.6183597106012642	[113]	[27]	-8	hSpCas9	negative selection	176548
25360509	25360532	15	-	26472758	Jiyoye	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-1.6923602920450411	[59]	[13]	-8	hSpCas9	negative selection	176549
25375563	25375586	15	-	26472758	Jiyoye	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.6123648048897716	[668]	[329]	-4	hSpCas9	negative selection	176550
25354610	25354633	15	-	26472758	Jiyoye	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	-0.06855804946052424	[266]	[191]	0	hSpCas9	negative selection	176551
25370882	25370905	15	+	26472758	KBM7	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.03275298325679571	[514,278]	[212,161]	0	hSpCas9	negative selection	367660
25375504	25375527	15	+	26472758	KBM7	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.5379064403190407	[323,508]	[222,353]	6	hSpCas9	negative selection	367661
25360442	25360465	15	-	26472758	KBM7	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.7774099681156799	[354,346]	[93,98]	-6	hSpCas9	negative selection	367662
25371539	25371562	15	-	26472758	KBM7	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.1815955933279616	[2562,2042]	[1110,802]	-2	hSpCas9	negative selection	367663
25375708	25375731	15	-	26472758	KBM7	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.43796544957499683	[630,461]	[213,163]	-4	hSpCas9	negative selection	367664
25371025	25371048	15	-	26472758	KBM7	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.5950832882361939	[687,386]	[491,265]	6	hSpCas9	negative selection	367665
25370854	25370877	15	+	26472758	KBM7	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.0837494884399379	[290,173]	[100,100]	-1	hSpCas9	negative selection	367666
25360509	25360532	15	-	26472758	KBM7	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	0.394361266833573	[108,95]	[86,41]	4	hSpCas9	negative selection	367667
25375563	25375586	15	-	26472758	KBM7	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.08443741622092027	[1702,2053]	[1072,839]	0	hSpCas9	negative selection	367668
25354610	25354633	15	-	26472758	KBM7	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.7086548119314339	[1042,733]	[599,739]	7	hSpCas9	negative selection	367669
25370882	25370905	15	+	26472758	Raji	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.14895621788618604	[214]	[44]	-1	hSpCas9	negative selection	558778
25375504	25375527	15	+	26472758	Raji	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.6595193429467106	[210]	[30]	-5	hSpCas9	negative selection	558779
25360442	25360465	15	-	26472758	Raji	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	1.0328365820085454	[138]	[65]	8	hSpCas9	negative selection	558780
25371539	25371562	15	-	26472758	Raji	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.46444363336602956	[786]	[251]	4	hSpCas9	negative selection	558781
25375708	25375731	15	-	26472758	Raji	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.28588443099572547	[204]	[57]	2	hSpCas9	negative selection	558782
25371025	25371048	15	-	26472758	Raji	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.059449058309897496	[305]	[73]	0	hSpCas9	negative selection	558783
25370854	25370877	15	+	26472758	Raji	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-1.3322396021835177	[216]	[19]	-7	hSpCas9	negative selection	558784
25360509	25360532	15	-	26472758	Raji	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-1.2711280878801303	[51]	[4]	-7	hSpCas9	negative selection	558785
25375563	25375586	15	-	26472758	Raji	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.056827814874319316	[1133]	[252]	0	hSpCas9	negative selection	558786
25354610	25354633	15	-	26472758	Raji	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.16156457352466247	[600]	[155]	1	hSpCas9	negative selection	558787
25370882	25370905	15	+	26472758	K562	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.18727482056283803	[308]	[296]	1	hSpCas9	negative selection	749896
25375504	25375527	15	+	26472758	K562	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.9391266343709463	[387]	[627]	7	hSpCas9	negative selection	749897
25360442	25360465	15	-	26472758	K562	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	1.2120633543540618	[247]	[484]	8	hSpCas9	negative selection	749898
25371539	25371562	15	-	26472758	K562	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.19963777493903434	[1864]	[1807]	1	hSpCas9	negative selection	749899
25375708	25375731	15	-	26472758	K562	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.9870151431909762	[357]	[598]	8	hSpCas9	negative selection	749900
25371025	25371048	15	-	26472758	K562	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	1.3052439203624906	[417]	[871]	9	hSpCas9	negative selection	749901
25370854	25370877	15	+	26472758	K562	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.6286311008081517	[271]	[354]	5	hSpCas9	negative selection	749902
25360509	25360532	15	-	26472758	K562	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-2.6190792724286913	[130]	[17]	-8	hSpCas9	negative selection	749903
25375563	25375586	15	-	26472758	K562	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.833959762985375	[1572]	[2366]	7	hSpCas9	negative selection	749904
25354610	25354633	15	-	26472758	K562	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.6466195081799095	[761]	[1006]	5	hSpCas9	negative selection	749905
25371024	25371047	15	-	26627737	DLD1	viability	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.20788296660233063	[732]	[372,308,133]	2	hSpCas9	negative selection	790119
25375530	25375553	15	-	26627737	DLD1	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.9546218019237462	[151]	[44,161,74]	8	hSpCas9	negative selection	790120
25371024	25371047	15	-	26627737	GBM cells	viability after 5 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.4010194432025579	[429]	[311,296]	6	hSpCas9	negative selection	872434
25375530	25375553	15	-	26627737	GBM cells	viability after 5 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8395353278067539	[123]	[128,108]	9	hSpCas9	negative selection	872435
25371024	25371047	15	-	26627737	GBM cells	viability after 13 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.5277738754790474	[429]	[369,308]	6	hSpCas9	negative selection	954749
25375530	25375553	15	-	26627737	GBM cells	viability after 13 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8619445201158642	[123]	[129,115]	8	hSpCas9	negative selection	954750
25371024	25371047	15	-	26627737	GBM cells	viability after 21 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	1.1032965858983448	[429]	[515,488]	9	hSpCas9	negative selection	1037064
25375530	25375553	15	-	26627737	GBM cells	viability after 21 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.19801869232871	[123]	[164,144]	9	hSpCas9	negative selection	1037065
25371024	25371047	15	-	26627737	RPE1	viability after 9 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	1.0400091079668	[1060]	[596,793]	6	hSpCas9	negative selection	1119379
25375530	25375553	15	-	26627737	RPE1	viability after 9 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.9821128378845203	[347]	[257,159]	6	hSpCas9	negative selection	1119380
25371024	25371047	15	-	26627737	RPE1	viability after 12 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	1.1471170580714576	[1060]	[658,601]	7	hSpCas9	negative selection	1201694
25375530	25375553	15	-	26627737	RPE1	viability after 12 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.115251313574446	[347]	[237,164]	6	hSpCas9	negative selection	1201695
25371024	25371047	15	-	26627737	RPE1	viability after 15 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	1.3207600276415081	[1060]	[736,761]	7	hSpCas9	negative selection	1284009
25375530	25375553	15	-	26627737	RPE1	viability after 15 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8812817182355892	[347]	[218,144]	5	hSpCas9	negative selection	1284010
25371024	25371047	15	-	26627737	RPE1	viability after 18 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.9815825548968807	[1060]	[372,770]	6	hSpCas9	negative selection	1366324
25375530	25375553	15	-	26627737	RPE1	viability after 18 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.1772230718032202	[347]	[237,184]	6	hSpCas9	negative selection	1366325
25371024	25371047	15	-	26627737	HeLa	viability after 8 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.5720329805791855	[843]	[521,599,512]	5	hSpCas9	negative selection	1448639
25375530	25375553	15	-	26627737	HeLa	viability after 8 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.1954071699347448	[119]	[100,79,169]	8	hSpCas9	negative selection	1448640
25371024	25371047	15	-	26627737	HeLa	viability after 12 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	-0.19043357266508998	[843]	[281,166,481]	-2	hSpCas9	negative selection	1530954
25375530	25375553	15	-	26627737	HeLa	viability after 12 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8523884220450995	[119]	[45,139,75]	6	hSpCas9	negative selection	1530955
25371024	25371047	15	-	26627737	HeLa	viability after 15 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	-0.4229933562792252	[843]	[195,203,378]	-4	hSpCas9	negative selection	1613269
25375530	25375553	15	-	26627737	HeLa	viability after 15 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8298820267818985	[119]	[12,130,119]	6	hSpCas9	negative selection	1613270
25371024	25371047	15	-	26627737	HeLa	viability after 18 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	-0.4353266771010984	[843]	[127,167,378]	-4	hSpCas9	negative selection	1695584
25375530	25375553	15	-	26627737	HeLa	viability after 18 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8426401330056733	[119]	[8,109,119]	6	hSpCas9	negative selection	1695585
25371024	25371047	15	-	26627737	HCT116	viability after 6 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	-0.19173259093688222	[1379]	[236,163]	-1	hSpCas9	negative selection	1777899
25375530	25375553	15	-	26627737	HCT116	viability after 6 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.7865772015417559	[626]	[2,86]	-4	hSpCas9	negative selection	1777900
25371024	25371047	15	-	26627737	HCT116	viability after 8 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.8115446700208429	[334]	[307,285,376]	7	hSpCas9	negative selection	1860214
25375530	25375553	15	-	26627737	HCT116	viability after 8 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.6917894719368599	[111]	[103,83,110]	6	hSpCas9	negative selection	1860215
25371024	25371047	15	-	26627737	HCT116	viability after 9 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	-0.020348594067351122	[1379]	[488,263]	0	hSpCas9	negative selection	1942529
25375530	25375553	15	-	26627737	HCT116	viability after 9 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-3.058272889554536	[626]	[42,1]	-9	hSpCas9	negative selection	1942530
25371024	25371047	15	-	26627737	HCT116	viability after 12 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.6911525953481455	[334]	[253,308,292]	6	hSpCas9	negative selection	2024844
25375530	25375553	15	-	26627737	HCT116	viability after 12 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.48450093512036607	[111]	[44,109,95]	5	hSpCas9	negative selection	2024845
25371024	25371047	15	-	26627737	HCT116	viability after 15 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.3750493028574974	[334]	[243,183,318]	3	hSpCas9	negative selection	2107159
25375530	25375553	15	-	26627737	HCT116	viability after 15 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.42597657184440163	[111]	[92,76,89]	4	hSpCas9	negative selection	2107160
25371024	25371047	15	-	26627737	HCT116	viability after 18 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.6531495517197309	[334]	[317,177,273]	5	hSpCas9	negative selection	2189474
25375530	25375553	15	-	26627737	HCT116	viability after 18 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.16735303548263336	[111]	[22,46,75]	-1	hSpCas9	negative selection	2189475
25371660	25371683	15	+	24336569	HL60	viability	TGGTGTGTTGTTTAACTTTCCGG	UBE3A	ENSG00000114062	-0.4905767659506348	[80]	[121]	-4	hSpCas9	negative selection	2304779
25371719	25371742	15	+	24336569	HL60	viability	CTTCCAATAACACGGATTAAAGG	UBE3A	ENSG00000114062	-1.3666641622651587	[445]	[365]	-8	hSpCas9	negative selection	2304780
25375502	25375525	15	+	24336569	HL60	viability	TATCTCAGAGCAGGAGTTGTTGG	UBE3A	ENSG00000114062	0.8975254060785655	[414]	[1635]	7	hSpCas9	negative selection	2304781
25375525	25375548	15	+	24336569	HL60	viability	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	-1.4207742737444953	[500]	[395]	-8	hSpCas9	negative selection	2304782
25375530	25375553	15	-	24336569	HL60	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.48488272192491255	[103]	[307]	4	hSpCas9	negative selection	2304783
25375550	25375573	15	+	24336569	HL60	viability	AGCTGAGCTTGCTCCTTTCTTGG	UBE3A	ENSG00000114062	0.10971168801154751	[613]	[1401]	1	hSpCas9	negative selection	2304784
25375560	25375583	15	+	24336569	HL60	viability	GCTCCTTTCTTGGAGGGATGAGG	UBE3A	ENSG00000114062	-1.3385307832030522	[771]	[645]	-8	hSpCas9	negative selection	2304785
25375597	25375620	15	+	24336569	HL60	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	1.3015953542887677	[133]	[698]	8	hSpCas9	negative selection	2304786
25375699	25375722	15	+	24336569	HL60	viability	TTCCACAGCCCTCAGTTAACTGG	UBE3A	ENSG00000114062	0.8907909088881996	[209]	[823]	7	hSpCas9	negative selection	2304787
25375707	25375730	15	-	24336569	HL60	viability	TACTACCACCAGTTAACTGAGGG	UBE3A	ENSG00000114062	1.7636674722316643	[279]	[2011]	9	hSpCas9	negative selection	2304788
25371660	25371683	15	+	24336569	KBM7	viability	TGGTGTGTTGTTTAACTTTCCGG	UBE3A	ENSG00000114062	0.6375881867137947	[36]	[156]	6	hSpCas9	negative selection	2371956
25371719	25371742	15	+	24336569	KBM7	viability	CTTCCAATAACACGGATTAAAGG	UBE3A	ENSG00000114062	0.8882433399968604	[247]	[1251]	7	hSpCas9	negative selection	2371957
25375502	25375525	15	+	24336569	KBM7	viability	TATCTCAGAGCAGGAGTTGTTGG	UBE3A	ENSG00000114062	0.747086712745649	[378]	[1734]	6	hSpCas9	negative selection	2371958
25375525	25375548	15	+	24336569	KBM7	viability	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	0.007160726763692615	[111]	[306]	0	hSpCas9	negative selection	2371959
25375530	25375553	15	-	24336569	KBM7	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.4257197625851432	[130]	[265]	-4	hSpCas9	negative selection	2371960
25375550	25375573	15	+	24336569	KBM7	viability	AGCTGAGCTTGCTCCTTTCTTGG	UBE3A	ENSG00000114062	0.9435035705782389	[500]	[2627]	7	hSpCas9	negative selection	2371961
25375560	25375583	15	+	24336569	KBM7	viability	GCTCCTTTCTTGGAGGGATGAGG	UBE3A	ENSG00000114062	-0.20571549059069924	[388]	[919]	-2	hSpCas9	negative selection	2371962
25375597	25375620	15	+	24336569	KBM7	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.6480226450516856	[211]	[368]	-5	hSpCas9	negative selection	2371963
25375699	25375722	15	+	24336569	KBM7	viability	TTCCACAGCCCTCAGTTAACTGG	UBE3A	ENSG00000114062	-0.6185653933615053	[254]	[452]	-5	hSpCas9	negative selection	2371964
25375707	25375730	15	-	24336569	KBM7	viability	TACTACCACCAGTTAACTGAGGG	UBE3A	ENSG00000114062	-0.7164841905071762	[393]	[653]	-5	hSpCas9	negative selection	2371965
25352150	25352173	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCTCAG	UBE3A	ENSG00000114062	0.12883397399525423	[86,65]	[25,8]	0	dCas9-VP64	positive selection	2424600
25357440	25357463	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATTGTTTGAACCTAG	UBE3A	ENSG00000114062	0.964443282063522	[91,283]	[89,70]	4	dCas9-VP64	positive selection	2426632
25357555	25357578	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAAGAGGTTGAGACCATCCTGG	UBE3A	ENSG00000114062	-0.08958274386455767	[205,108]	[27,36]	0	dCas9-VP64	positive selection	2448548
25411387	25411410	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACACGG	UBE3A	ENSG00000114062	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458952
25405828	25405851	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AACTTCCTATAGCCAAGTATTGG	UBE3A	ENSG00000114062	0.8874062414949876	[98,175]	[33,79]	3	dCas9-VP64	positive selection	2463266
25405833	25405856	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATAACCAATACTTGGCTATAGG	UBE3A	ENSG00000114062	0.35046892941620467	[234,251]	[71,63]	1	dCas9-VP64	positive selection	2463267
25405840	25405863	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAATGTGGATAACCAATACTTGG	UBE3A	ENSG00000114062	-0.4176628094104553	[417,445]	[33,110]	-2	dCas9-VP64	positive selection	2463268
25358312	25358335	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGACAG	UBE3A	ENSG00000114062	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476908
25352150	25352173	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCTCAG	UBE3A	ENSG00000114062	-0.30672599620467045	[261,149]	[50,57]	-3	dCas9-VP64	positive selection	2519855
25357440	25357463	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATTGTTTGAACCTAG	UBE3A	ENSG00000114062	-0.320288383300443	[193,176]	[58,37]	-3	dCas9-VP64	positive selection	2521887
25357555	25357578	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAAGAGGTTGAGACCATCCTGG	UBE3A	ENSG00000114062	-0.6819838415228677	[64,59]	[12,11]	-6	dCas9-VP64	positive selection	2543803
25411387	25411410	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACACGG	UBE3A	ENSG00000114062	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554207
25405828	25405851	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AACTTCCTATAGCCAAGTATTGG	UBE3A	ENSG00000114062	-0.113468995011061	[308,555]	[94,162]	-1	dCas9-VP64	positive selection	2558521
25405833	25405856	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATAACCAATACTTGGCTATAGG	UBE3A	ENSG00000114062	-0.3109903403916032	[285,159]	[39,75]	-3	dCas9-VP64	positive selection	2558522
25405840	25405863	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAATGTGGATAACCAATACTTGG	UBE3A	ENSG00000114062	0.14193301373913947	[353,180]	[145,50]	1	dCas9-VP64	positive selection	2558523
25358312	25358335	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGACAG	UBE3A	ENSG00000114062	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572163
25375555	25375578	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	0.3474255897275203	[2,3]	[1,4]	7	hSpCas9	positive selection	3030622
25375530	25375553	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.3137003593426364	[3,2]	[4,1]	6	hSpCas9	positive selection	3030623
25371459	25371482	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	0.3184056319986657	[3,3]	[2,4]	6	hSpCas9	positive selection	3030624
25371530	25371553	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	-0.1297835029409919	[4,4]	[3,2]	-2	hSpCas9	positive selection	3030625
25375555	25375578	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	0.21177560731971237	[2,2]	[1,1]	4	hSpCas9	positive selection	3098480
25375530	25375553	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.16240841478089743	[3,3]	[3,1]	3	hSpCas9	positive selection	3098481
25371459	25371482	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	0.10741778147311153	[3,3]	[2,2]	2	hSpCas9	positive selection	3098482
25371530	25371553	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	0.26265141311492013	[4,4]	[3,3]	4	hSpCas9	positive selection	3098483
25354352	25354375		-	24336571	A375	resistance to PLX after 7 days	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.09462962750565818	[43,47]	[40,43]	-3	hSpCas9	positive selection	3153991
25354352	25354375		+	24336571	A375	resistance to PLX after 7 days	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.350685643348259	[30,32]	[24,24]	-8	hSpCas9	positive selection	3153992
25375530	25375553		-	24336571	A375	resistance to PLX after 7 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.4314072471471332	[5,7]	[4,4]	-9	hSpCas9	positive selection	3153993
25405470	25405493		+	24336571	A375	resistance to PLX after 7 days	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	-0.18023572444845687	[18,20]	[14,18]	-6	hSpCas9	positive selection	3153994
25375525	25375548		+	24336571	A375	resistance to PLX after 7 days	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	-0.1821986718875795	[8,8]	[7,7]	-6	hSpCas9	positive selection	3153995
25354352	25354375		-	24336571	A375	resistance to PLX after 14 days	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.4508299593628877	[40,45]	[29,25]	4	hSpCas9	positive selection	3211784
25354352	25354375		+	24336571	A375	resistance to PLX after 14 days	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-1.2410280156542373	[37,25]	[5,5]	-9	hSpCas9	positive selection	3211785
25375530	25375553		-	24336571	A375	resistance to PLX after 14 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.03210583568240799	[3,7]	[2,1]	0	hSpCas9	positive selection	3211786
25405470	25405493		+	24336571	A375	resistance to PLX after 14 days	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	0.2009910071472001	[15,13]	[6,7]	2	hSpCas9	positive selection	3211787
25375525	25375548		+	24336571	A375	resistance to PLX after 14 days	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	-0.48469833102048576	[13,6]	[2,2]	-6	hSpCas9	positive selection	3211788
25354352	25354375		-	24336571	A375	viability after 7 days	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.40846778082602464	[35]	[43,47]	6	hSpCas9	negative selection	3269577
25354352	25354375		+	24336571	A375	viability after 7 days	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.10728679583449918	[36]	[30,32]	-1	hSpCas9	negative selection	3269578
25375530	25375553		-	24336571	A375	viability after 7 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.0001304074514115	[14]	[5,7]	-9	hSpCas9	negative selection	3269579
25405470	25405493		+	24336571	A375	viability after 7 days	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	0.08964426413540483	[18]	[18,20]	1	hSpCas9	negative selection	3269580
25375525	25375548		+	24336571	A375	viability after 7 days	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	-0.015331759861460403	[9]	[8,8]	0	hSpCas9	negative selection	3269581
25354352	25354375		-	24336571	A375	viability after 14 days	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.3501452753493166	[35]	[40,45]	4	hSpCas9	negative selection	3327370
25354352	25354375		+	24336571	A375	viability after 14 days	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.09525210351748625	[36]	[37,25]	-1	hSpCas9	negative selection	3327371
25375530	25375553		-	24336571	A375	viability after 14 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.1602786948884871	[14]	[3,7]	-9	hSpCas9	negative selection	3327372
25405470	25405493		+	24336571	A375	viability after 14 days	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	-0.2640361122401025	[18]	[15,13]	-3	hSpCas9	negative selection	3327373
25375525	25375548		+	24336571	A375	viability after 14 days	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	0.21814974945889493	[9]	[13,6]	3	hSpCas9	negative selection	3327374
25408622	25408645	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.4569193062202875	[209,209]	[0,0]	-3	hSpCas9	positive selection	3400061
25354352	25354375	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3400062
25354352	25354375	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-1.2305138223772163	[358,358]	[0,0]	-7	hSpCas9	positive selection	3400063
25375554	25375577	15	+	26780180	HT29	viability (Avana library 4 designs)	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	0.458444808981766	[]	[]	1	hSpCas9	negative selection	3469551
25375530	25375553	15	-	26780180	HT29	viability (Avana library 4 designs)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.889627072243229	[]	[]	3	hSpCas9	negative selection	3469552
25371459	25371482	15	-	26780180	HT29	viability (Avana library 4 designs)	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	0.594466121450039	[]	[]	2	hSpCas9	negative selection	3469553
25371529	25371552	15	+	26780180	HT29	viability (Avana library 4 designs)	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	-0.0948994836499873	[]	[]	-1	hSpCas9	negative selection	3469554
25371529	25371552	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	-2.13741942516287	[]	[]	-3	hSpCas9	negative selection	3574843
25375530	25375553	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-4.48891857925924	[]	[]	-5	hSpCas9	negative selection	3574844
25375554	25375577	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	6.00331955432103	[]	[]	9	hSpCas9	negative selection	3574845
25371459	25371482	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	-7.12126227043536	[]	[]	-6	hSpCas9	negative selection	3574846
25371524	25371547	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGATAGGTGATAGCTCACAGGG	UBE3A	ENSG00000114062	4.66159831055474	[]	[]	7	hSpCas9	negative selection	3574847
25375708	25375731	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-5.52521736176141	[]	[]	-6	hSpCas9	negative selection	3574848
25371529	25371552	15	+	26780180	A375	viability (Avana lentiGuide)	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	-1.87038953917944	[]	[]	-3	hSpCas9	negative selection	3683502
25375530	25375553	15	-	26780180	A375	viability (Avana lentiGuide)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.54838441737286	[]	[]	-3	hSpCas9	negative selection	3683503
25375554	25375577	15	+	26780180	A375	viability (Avana lentiGuide)	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	12.8988128718669	[]	[]	7	hSpCas9	negative selection	3683504
25371459	25371482	15	-	26780180	A375	viability (Avana lentiGuide)	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	1.27472934076805	[]	[]	1	hSpCas9	negative selection	3683505
25371524	25371547	15	-	26780180	A375	viability (Avana lentiGuide)	AGGATAGGTGATAGCTCACAGGG	UBE3A	ENSG00000114062	6.27742838327737	[]	[]	5	hSpCas9	negative selection	3683506
25375708	25375731	15	-	26780180	A375	viability (Avana lentiGuide)	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-1.29625537588747	[]	[]	-2	hSpCas9	negative selection	3683507
25371529	25371552	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	-0.08746184107082167	[5]	[5,5]	-1	hSpCas9	positive selection	3792109
25375530	25375553	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.20300483243376435	[4]	[4,3]	-3	hSpCas9	positive selection	3792110
25375554	25375577	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	0.1867418720173667	[4]	[5,4]	5	hSpCas9	positive selection	3792111
25371459	25371482	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	-0.23511636052923535	[6]	[4,5]	-4	hSpCas9	positive selection	3792112
25371524	25371547	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGATAGGTGATAGCTCACAGGG	UBE3A	ENSG00000114062	0.06324470075850304	[5]	[5,4]	1	hSpCas9	positive selection	3792113
25375708	25375731	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.3977969421749145	[5]	[2,4]	-5	hSpCas9	positive selection	3792114
25371529	25371552	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGCTATCACCTATCCTTGAGG	UBE3A	ENSG00000114062	0.034588066787142296	[6]	[5,4]	0	hSpCas9	positive selection	3900716
25375530	25375553	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.5252319403152463	[4]	[3,1]	-6	hSpCas9	positive selection	3900717
25375554	25375577	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCTTGCTCCTTTCTTGGAGGG	UBE3A	ENSG00000114062	-0.6040182890644148	[5]	[4,0]	-6	hSpCas9	positive selection	3900718
25371459	25371482	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATATTGATGCCATTAGAAGGG	UBE3A	ENSG00000114062	-0.0068490991465245165	[5]	[5,3]	0	hSpCas9	positive selection	3900719
25371524	25371547	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGATAGGTGATAGCTCACAGGG	UBE3A	ENSG00000114062	-0.9432403184521373	[5]	[2,1]	-8	hSpCas9	positive selection	3900720
25375708	25375731	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.01968993654363345	[5]	[5,4]	0	hSpCas9	positive selection	3900721
25408622	25408645	15	-	26780180	A375	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	1.30151572023542	[]	[]	7	hSpCas9	negative selection	4009810
25375597	25375620	15	+	26780180	A375	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.373982154445256	[]	[]	0	hSpCas9	negative selection	4009811
25354352	25354375	15	-	26780180	A375	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.722603117470429	[]	[]	2	hSpCas9	negative selection	4009812
25354352	25354375	15	+	26780180	A375	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	1.41322725719024	[]	[]	7	hSpCas9	negative selection	4009813
25375530	25375553	15	-	26780180	A375	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.0924656688985366	[]	[]	0	hSpCas9	negative selection	4009814
25408612	25408635	15	+	26780180	A375	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	1.6187119959166	[]	[]	8	hSpCas9	negative selection	4009815
25408622	25408645	15	-	26780180	HT29	viability (GeCKOv2 library)	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.471536265947379	[]	[]	1	hSpCas9	negative selection	4117776
25375597	25375620	15	+	26780180	HT29	viability (GeCKOv2 library)	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.783553565945559	[]	[]	3	hSpCas9	negative selection	4117777
25354352	25354375	15	-	26780180	HT29	viability (GeCKOv2 library)	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.271518202427216	[]	[]	0	hSpCas9	negative selection	4117778
25354352	25354375	15	+	26780180	HT29	viability (GeCKOv2 library)	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.834186382426644	[]	[]	3	hSpCas9	negative selection	4117779
25375530	25375553	15	-	26780180	HT29	viability (GeCKOv2 library)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.107194447031146	[]	[]	0	hSpCas9	negative selection	4117780
25408612	25408635	15	+	26780180	HT29	viability (GeCKOv2 library)	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.379742774725833	[]	[]	1	hSpCas9	negative selection	4117781
25354352	25354375	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.27598152122623393	[5]	[4,4]	7	hSpCas9	positive selection	4180664
25354352	25354375	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.23713050575560785	[5]	[2,2]	-5	hSpCas9	positive selection	4180665
25375530	25375553	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.38432909169300455	[2]	[0,1]	-7	hSpCas9	positive selection	4180666
25405470	25405493	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	-0.013355645899571125	[4]	[2,2]	0	hSpCas9	positive selection	4180667
25375525	25375548	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	-0.009007636407338981	[2]	[1,1]	0	hSpCas9	positive selection	4180668
25354352	25354375	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.8163690843586273	[5]	[5,4,2,3]	5	hSpCas9	positive selection	4244686
25354352	25354375	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.07913530249167017	[3]	[0,4,2,0]	-1	hSpCas9	positive selection	4244687
25375530	25375553	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.21236104328214145	[4]	[2,1,4,0]	1	hSpCas9	positive selection	4244688
25405470	25405493	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTCAATGTCGTCAGACTGAGG	UBE3A	ENSG00000114062	0.8507821869762913	[4]	[1,3,1,3]	5	hSpCas9	positive selection	4244689
25375525	25375548	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCACCTTTCGAGTTCTCAAGG	UBE3A	ENSG00000114062	1.014110194660639	[1]	[0,4,0,0]	7	hSpCas9	positive selection	4244690
25375530	25375553	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.09393677585418048	[0]	[0,0]	2	hSpCas9	positive selection	4306296
25375597	25375620	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.4731787604843087	[2]	[3,1]	8	hSpCas9	positive selection	4306297
25408612	25408635	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.00015372316022671528	[4]	[2,3]	0	hSpCas9	positive selection	4306298
25408622	25408645	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.20936680507704966	[3]	[3,0]	-4	hSpCas9	positive selection	4370545
25354352	25354375	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.44731273402117405	[1]	[0,0]	-7	hSpCas9	positive selection	4370546
25354352	25354375	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.24656020094165237	[3]	[2,1]	-5	hSpCas9	positive selection	4370547
25370855	25370877	15	+	27760321	OCIAML3	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.2530136191559096	[460,424]	[322,529]	3	hSpCas9	negative selection	4451858
25370907	25370929	15	-	27760321	OCIAML3	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.41959031997374174	[298,242]	[118,207]	-4	hSpCas9	negative selection	4451859
25371381	25371403	15	-	27760321	OCIAML3	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.5754387326517225	[45,40]	[4,45]	-5	hSpCas9	negative selection	4451860
25375530	25375552	15	-	27760321	OCIAML3	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.28607699065269165	[225,213]	[163,269]	3	hSpCas9	negative selection	4451861
25375598	25375620	15	+	27760321	OCIAML3	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	1.4143232698969852	[35,43]	[23,162]	9	hSpCas9	negative selection	4451862
25370855	25370877	15	+	27760321	OCIAML2	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.10658687064023478	[460,424]	[368,407]	1	hSpCas9	negative selection	4535321
25370907	25370929	15	-	27760321	OCIAML2	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.025423374222675044	[298,242]	[205,242]	0	hSpCas9	negative selection	4535322
25371381	25371403	15	-	27760321	OCIAML2	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-1.164883364590911	[45,40]	[0,34]	-8	hSpCas9	negative selection	4535323
25375530	25375552	15	-	27760321	OCIAML2	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.6653345057057537	[225,213]	[104,121]	-6	hSpCas9	negative selection	4535324
25375598	25375620	15	+	27760321	OCIAML2	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.3497250118231192	[35,43]	[29,19]	-4	hSpCas9	negative selection	4535325
25370855	25370877	15	+	27760321	MV411	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.7767793442455995	[460,424]	[192,136]	-5	hSpCas9	negative selection	4618784
25370907	25370929	15	-	27760321	MV411	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.9491041708190796	[298,242]	[26,189]	-6	hSpCas9	negative selection	4618785
25371381	25371403	15	-	27760321	MV411	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.19657356661297465	[45,40]	[40,0]	-1	hSpCas9	negative selection	4618786
25375530	25375552	15	-	27760321	MV411	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.14183173511189784	[225,213]	[91,262]	1	hSpCas9	negative selection	4618787
25375598	25375620	15	+	27760321	MV411	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	1.149573660508247	[35,43]	[97,0]	8	hSpCas9	negative selection	4618788
25370855	25370877	15	+	27760321	HL60	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.6178899230390894	[460,424]	[598,508]	7	hSpCas9	negative selection	4702247
25370907	25370929	15	-	27760321	HL60	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	1.3278869136185438	[298,242]	[679,417]	9	hSpCas9	negative selection	4702248
25371381	25371403	15	-	27760321	HL60	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.34624480642873046	[45,40]	[24,30]	-4	hSpCas9	negative selection	4702249
25375530	25375552	15	-	27760321	HL60	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.02318018520143339	[225,213]	[144,210]	0	hSpCas9	negative selection	4702250
25375598	25375620	15	+	27760321	HL60	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-3.0466055973091914	[35,43]	[3,3]	-9	hSpCas9	negative selection	4702251
25370855	25370877	15	+	27760321	HT1080	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	2.0201851373572692	[424,331]	[709,503]	9	hSpCas9	negative selection	4785710
25370907	25370929	15	-	27760321	HT1080	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.8617761133929802	[242,189]	[140,173]	4	hSpCas9	negative selection	4785711
25371381	25371403	15	-	27760321	HT1080	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	1.5042205337140973	[40,31]	[56,23]	7	hSpCas9	negative selection	4785712
25375530	25375552	15	-	27760321	HT1080	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.09564277679528499	[213,166]	[82,78]	0	hSpCas9	negative selection	4785713
25375598	25375620	15	+	27760321	HT1080	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.962683300663858	[43,34]	[34,25]	5	hSpCas9	negative selection	4785714
25370855	25370877	15	+	27760321	HT29	viability after 7 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.34950655022656635	[424,331]	[425,482,246]	-5	hSpCas9	negative selection	4869173
25370907	25370929	15	-	27760321	HT29	viability after 7 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.14742666008043304	[242,189]	[294,343,124]	-2	hSpCas9	negative selection	4869174
25371381	25371403	15	-	27760321	HT29	viability after 7 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.3484330163658176	[40,31]	[65,21,26]	-5	hSpCas9	negative selection	4869175
25375530	25375552	15	-	27760321	HT29	viability after 7 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.3437302935734632	[213,166]	[464,241,248]	5	hSpCas9	negative selection	4869176
25375598	25375620	15	+	27760321	HT29	viability after 7 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.5958158722647666	[43,34]	[158,1,80]	8	hSpCas9	negative selection	4869177
25370855	25370877	15	+	27760321	HT29	viability after 25 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.33127862407846076	[424,331]	[629,628,346]	3	hSpCas9	negative selection	4952636
25370907	25370929	15	-	27760321	HT29	viability after 25 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.32199369995524874	[242,189]	[300,317,308]	3	hSpCas9	negative selection	4952637
25371381	25371403	15	-	27760321	HT29	viability after 25 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-1.5755320596185012	[40,31]	[31,1,5]	-7	hSpCas9	negative selection	4952638
25375530	25375552	15	-	27760321	HT29	viability after 25 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.16831450786753954	[213,166]	[181,176,225]	-2	hSpCas9	negative selection	4952639
25375598	25375620	15	+	27760321	HT29	viability after 25 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.48444000117871555	[43,34]	[28,44,21]	-4	hSpCas9	negative selection	4952640
25370855	25370877	15	+	27760321	HT29	viability after 22 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.014900614159894437	[424,331]	[440,429,427]	0	hSpCas9	negative selection	5036099
25370907	25370929	15	-	27760321	HT29	viability after 22 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.18130565781050922	[242,189]	[455,193,195]	1	hSpCas9	negative selection	5036100
25371381	25371403	15	-	27760321	HT29	viability after 22 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.018117867118174313	[40,31]	[71,29,21]	0	hSpCas9	negative selection	5036101
25375530	25375552	15	-	27760321	HT29	viability after 22 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.24676518837724704	[213,166]	[157,231,397]	2	hSpCas9	negative selection	5036102
25375598	25375620	15	+	27760321	HT29	viability after 22 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.05953439707756214	[43,34]	[4,47,79]	0	hSpCas9	negative selection	5036103
25370855	25370877	15	+	27760321	HT29	viability after 19 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.18348209275747068	[424,331]	[356,787,321]	1	hSpCas9	negative selection	5119562
25370907	25370929	15	-	27760321	HT29	viability after 19 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.16707918812843048	[242,189]	[310,273,90]	-1	hSpCas9	negative selection	5119563
25371381	25371403	15	-	27760321	HT29	viability after 19 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-1.4669072884901633	[40,31]	[12,14,16]	-7	hSpCas9	negative selection	5119564
25375530	25375552	15	-	27760321	HT29	viability after 19 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.06885906850487677	[213,166]	[339,206,152]	0	hSpCas9	negative selection	5119565
25375598	25375620	15	+	27760321	HT29	viability after 19 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-1.3353718061091246	[43,34]	[16,0,34]	-7	hSpCas9	negative selection	5119566
25370855	25370877	15	+	27760321	HT29	viability after 16 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.07269768641131631	[424,331]	[613,559,174]	0	hSpCas9	negative selection	5203025
25370907	25370929	15	-	27760321	HT29	viability after 16 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.1690423210272689	[242,189]	[244,289,278]	1	hSpCas9	negative selection	5203026
25371381	25371403	15	-	27760321	HT29	viability after 16 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.05126402342346026	[40,31]	[44,29,43]	0	hSpCas9	negative selection	5203027
25375530	25375552	15	-	27760321	HT29	viability after 16 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.21132742627276402	[213,166]	[228,75,437]	2	hSpCas9	negative selection	5203028
25375598	25375620	15	+	27760321	HT29	viability after 16 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-1.9918668052106678	[43,34]	[14,0,17]	-8	hSpCas9	negative selection	5203029
25370855	25370877	15	+	27760321	HT29	viability after 13 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.21743773173309816	[424,331]	[337,432,362]	-3	hSpCas9	negative selection	5286488
25370907	25370929	15	-	27760321	HT29	viability after 13 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	0.11583415096313654	[242,189]	[230,353,233]	1	hSpCas9	negative selection	5286489
25371381	25371403	15	-	27760321	HT29	viability after 13 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-0.9176008514625185	[40,31]	[56,1,8]	-7	hSpCas9	negative selection	5286490
25375530	25375552	15	-	27760321	HT29	viability after 13 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.04061595591927447	[213,166]	[179,238,224]	0	hSpCas9	negative selection	5286491
25375598	25375620	15	+	27760321	HT29	viability after 13 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.8874723328435792	[43,34]	[2,21,47]	-7	hSpCas9	negative selection	5286492
25370855	25370877	15	+	27760321	HT29	viability after 10 days	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.31561965142168996	[424,331]	[380,631,748]	4	hSpCas9	negative selection	5369951
25370907	25370929	15	-	27760321	HT29	viability after 10 days	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.08893240680531633	[242,189]	[390,222,149]	-1	hSpCas9	negative selection	5369952
25371381	25371403	15	-	27760321	HT29	viability after 10 days	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	0.591113567334816	[40,31]	[188,15,0]	7	hSpCas9	negative selection	5369953
25375530	25375552	15	-	27760321	HT29	viability after 10 days	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.18760619306643767	[213,166]	[189,194,421]	2	hSpCas9	negative selection	5369954
25375598	25375620	15	+	27760321	HT29	viability after 10 days	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.41769063514562443	[43,34]	[15,10,166]	5	hSpCas9	negative selection	5369955
25370855	25370877	15	+	27760321	MOLM13	viability	AGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.5543933296564059	[460,424]	[406,332]	4	hSpCas9	negative selection	5453414
25370907	25370929	15	-	27760321	MOLM13	viability	AACAAGAAAGGTCCTCGAGTGG	UBE3A	ENSG00000114062	-0.1709649682208524	[298,242]	[52,204]	-1	hSpCas9	negative selection	5453415
25371381	25371403	15	-	27760321	MOLM13	viability	GTATATTTGTCACCTAACGTGG	UBE3A	ENSG00000114062	-1.5307461625034229	[45,40]	[1,13]	-7	hSpCas9	negative selection	5453416
25375530	25375552	15	-	27760321	MOLM13	viability	CTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-2.103151946097819	[225,213]	[29,27]	-8	hSpCas9	negative selection	5453417
25375598	25375620	15	+	27760321	MOLM13	viability	ATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-4.512678622687458	[35,43]	[0,0]	-9	hSpCas9	negative selection	5453418
25438813	25438836	15	+	27661255	K562	viability	GGCAGAGGTGAAGCGTAAGTAGG	UBE3A	ENSG00000114062	0.16879544795811663	[305,320]	[270,289]	6	dCas9-KRAB	negative selection	5521168
25439004	25439027	15	+	27661255	K562	viability	GCGGCGCAAGACGGGAGGACTGG	UBE3A	ENSG00000114062	0.3179010316972867	[323,348]	[420,260]	8	dCas9-KRAB	negative selection	5521169
25439026	25439049	15	+	27661255	K562	viability	GCTGGGCGGGCCGAGTATCCCGG	UBE3A	ENSG00000114062	-0.25972826862016607	[301,372]	[246,204]	-6	dCas9-KRAB	negative selection	5521170
25438524	25438547	15	-	27661255	K562	viability	GAGGGCGACTACGACCAGTGAGG	UBE3A	ENSG00000114062	0.12523168316897082	[1581,1740]	[1511,1387]	4	dCas9-KRAB	negative selection	5521171
25438595	25438618	15	-	27661255	K562	viability	GGGTCCCGCATGAGCCCCGGCGG	UBE3A	ENSG00000114062	-0.06156265482431633	[1205,1130]	[990,813]	-2	dCas9-KRAB	negative selection	5521172
25438935	25438958	15	-	27661255	K562	viability	GGTGACTACAGGAGACGACGGGG	UBE3A	ENSG00000114062	-0.0754306462262246	[743,709]	[556,546]	-3	dCas9-KRAB	negative selection	5521173
25438946	25438969	15	-	27661255	K562	viability	GCTGGGCTCGGGGTGACTACAGG	UBE3A	ENSG00000114062	0.08577426633309027	[287,294]	[300,200]	3	dCas9-KRAB	negative selection	5521174
25375530	25375553	15	-	27260156	BXPC3	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.4109744597931861	[10]	[1,6,6,0]	-9	hSpCas9	negative selection	5578756
25375597	25375620	15	+	27260156	BXPC3	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.06837682903371467	[236]	[243,262,232,303]	1	hSpCas9	negative selection	5578757
25408612	25408635	15	+	27260156	BXPC3	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.3365789723571937	[1026]	[1152,1442,1179,1693]	7	hSpCas9	negative selection	5578758
25408622	25408645	15	-	27260156	BXPC3	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.031635297284756836	[512]	[457,583,549,612]	0	hSpCas9	negative selection	5643005
25354352	25354375	15	-	27260156	BXPC3	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.41186352803141935	[180]	[224,278,197,310]	8	hSpCas9	negative selection	5643006
25354352	25354375	15	+	27260156	BXPC3	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.27891489512217027	[791]	[1072,884,942,1123]	6	hSpCas9	negative selection	5643007
25375530	25375553	15	-	27260156	A673	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.5607025781946353	[10]	[2,6,2,22]	-8	hSpCas9	negative selection	5700007
25375597	25375620	15	+	27260156	A673	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.21390543617304014	[236]	[351,169,218,254]	-5	hSpCas9	negative selection	5700008
25408612	25408635	15	+	27260156	A673	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.34160057374374775	[1026]	[1599,1240,1785,1634]	7	hSpCas9	negative selection	5700009
25408622	25408645	15	-	27260156	A673	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.2400137943427571	[512]	[564,493,525,504]	-5	hSpCas9	negative selection	5764256
25354352	25354375	15	-	27260156	A673	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.02973175088292046	[180]	[253,205,270,155]	0	hSpCas9	negative selection	5764257
25354352	25354375	15	+	27260156	A673	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.05694435470262349	[791]	[903,894,866,992]	-1	hSpCas9	negative selection	5764258
25375530	25375553	15	-	27260156	A375	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-3.6820385995773233	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	5821258
25375597	25375620	15	+	27260156	A375	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.35628049404308515	[236]	[333,445,463,202]	5	hSpCas9	negative selection	5821259
25408612	25408635	15	+	27260156	A375	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.10219676202888595	[1026]	[1237,1729,909,1323]	1	hSpCas9	negative selection	5821260
25408622	25408645	15	-	27260156	A375	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.18652231897065763	[512]	[1011,699,411,613]	2	hSpCas9	negative selection	5885507
25354352	25354375	15	-	27260156	A375	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.2559810172154775	[180]	[297,330,331,79]	4	hSpCas9	negative selection	5885508
25354352	25354375	15	+	27260156	A375	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.22824572624964412	[791]	[657,940,770,803]	-3	hSpCas9	negative selection	5885509
25375530	25375553	15	-	27260156	COLO741	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.327837257081911	[10]	[15,0,0]	-9	hSpCas9	negative selection	5942509
25375597	25375620	15	+	27260156	COLO741	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.10403932090964041	[236]	[333,261,254]	-2	hSpCas9	negative selection	5942510
25408612	25408635	15	+	27260156	COLO741	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.44865145770212633	[1026]	[2095,1760,1554]	8	hSpCas9	negative selection	5942511
25408622	25408645	15	-	27260156	COLO741	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.016978237601209423	[512]	[872,656,488]	0	hSpCas9	negative selection	6006758
25354352	25354375	15	-	27260156	COLO741	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.17028692834109216	[180]	[243,179,347]	3	hSpCas9	negative selection	6006759
25354352	25354375	15	+	27260156	COLO741	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.023212897727341142	[791]	[966,1092,927]	0	hSpCas9	negative selection	6006760
25375530	25375553	15	-	27260156	CAL120	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.1134009136737415	[10]	[0,0,15]	-9	hSpCas9	negative selection	6063760
25375597	25375620	15	+	27260156	CAL120	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.33659529714591374	[236]	[221,529,342]	5	hSpCas9	negative selection	6063761
25408612	25408635	15	+	27260156	CAL120	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.6061856054236205	[1026]	[2340,1894,1663]	8	hSpCas9	negative selection	6063762
25408622	25408645	15	-	27260156	CAL120	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.4785738489135195	[512]	[799,706,1142]	7	hSpCas9	negative selection	6128009
25354352	25354375	15	-	27260156	CAL120	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.40907741503745	[180]	[136,284,447]	6	hSpCas9	negative selection	6128010
25354352	25354375	15	+	27260156	CAL120	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.1975430527330646	[791]	[982,1314,1070]	3	hSpCas9	negative selection	6128011
25375530	25375553	15	-	27260156	CADOES1	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.5151757237525629	[10]	[23,3,26,2]	8	hSpCas9	negative selection	6185011
25375597	25375620	15	+	27260156	CADOES1	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.04843065764378873	[236]	[182,255,117,298]	-1	hSpCas9	negative selection	6185012
25408612	25408635	15	+	27260156	CADOES1	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.30612781976803416	[1026]	[1166,1122,1092,1346]	5	hSpCas9	negative selection	6185013
25408622	25408645	15	-	27260156	CADOES1	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.18408804891491587	[512]	[590,455,601,517]	3	hSpCas9	negative selection	6249260
25354352	25354375	15	-	27260156	CADOES1	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.010548172617673046	[180]	[196,181,161,135]	0	hSpCas9	negative selection	6249261
25354352	25354375	15	+	27260156	CADOES1	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.026766744373282192	[791]	[806,743,620,719]	0	hSpCas9	negative selection	6249262
25375530	25375553	15	-	27260156	EWS502	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.6408071621954088	[10]	[0,0,0,12]	-9	hSpCas9	negative selection	6306262
25375597	25375620	15	+	27260156	EWS502	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.14825065475311394	[236]	[202,168,289,250]	-3	hSpCas9	negative selection	6306263
25408612	25408635	15	+	27260156	EWS502	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.2874582079384451	[1026]	[1256,1247,1459,1355]	5	hSpCas9	negative selection	6306264
25408622	25408645	15	-	27260156	EWS502	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.045031309774185846	[512]	[353,748,484,527]	-1	hSpCas9	negative selection	6370511
25354352	25354375	15	-	27260156	EWS502	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.0849528898383003	[180]	[154,256,139,267]	1	hSpCas9	negative selection	6370512
25354352	25354375	15	+	27260156	EWS502	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.019828032673148255	[791]	[664,947,961,741]	0	hSpCas9	negative selection	6370513
25375530	25375553	15	-	27260156	EW8	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.6089562467566738	[10]	[14,0,1,6]	-8	hSpCas9	negative selection	6427513
25375597	25375620	15	+	27260156	EW8	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.22659388375494816	[236]	[125,205,212,98]	-4	hSpCas9	negative selection	6427514
25408612	25408635	15	+	27260156	EW8	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.15347936416829633	[1026]	[953,1034,716,1032]	3	hSpCas9	negative selection	6427515
25408622	25408645	15	-	27260156	EW8	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.1737090772153852	[512]	[621,383,444,443]	3	hSpCas9	negative selection	6491762
25354352	25354375	15	-	27260156	EW8	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.1435265049150598	[180]	[152,127,96,160]	-3	hSpCas9	negative selection	6491763
25354352	25354375	15	+	27260156	EW8	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.06435943979402037	[791]	[510,749,541,651]	-1	hSpCas9	negative selection	6491764
25375530	25375553	15	-	27260156	CORL105	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.03947540757414103	[10]	[1,8,13,24]	0	hSpCas9	negative selection	6548764
25375597	25375620	15	+	27260156	CORL105	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.1371518131307934	[236]	[201,164,392,270]	-3	hSpCas9	negative selection	6548765
25408612	25408635	15	+	27260156	CORL105	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.09814379684558827	[1026]	[1175,1316,1614,1086]	1	hSpCas9	negative selection	6548766
25408622	25408645	15	-	27260156	CORL105	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.0051810744861831015	[512]	[706,396,543,743]	0	hSpCas9	negative selection	6613013
25354352	25354375	15	-	27260156	CORL105	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.2953657808325283	[180]	[246,96,199,154]	-5	hSpCas9	negative selection	6613014
25354352	25354375	15	+	27260156	CORL105	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.04299135315163782	[791]	[853,893,1075,801]	-1	hSpCas9	negative selection	6613015
25375530	25375553	15	-	27260156	HS294T	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.2883355429758554	[10]	[2,4,1,3]	-4	hSpCas9	negative selection	6670015
25375597	25375620	15	+	27260156	HS294T	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.4406283749933715	[236]	[48,54,65,108]	-6	hSpCas9	negative selection	6670016
25408612	25408635	15	+	27260156	HS294T	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.3086079982659151	[1026]	[538,466,477,474]	4	hSpCas9	negative selection	6670017
25408622	25408645	15	-	27260156	HS294T	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.6187548348509831	[512]	[337,321,185,379]	7	hSpCas9	negative selection	6734264
25354352	25354375	15	-	27260156	HS294T	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.5796573583992506	[180]	[99,85,68,175]	7	hSpCas9	negative selection	6734265
25354352	25354375	15	+	27260156	HS294T	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.22313812696899837	[791]	[307,236,382,539]	3	hSpCas9	negative selection	6734266
25375530	25375553	15	-	27260156	HCC44	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.5883903871636846	[10]	[1,34,3,26]	8	hSpCas9	negative selection	6791266
25375597	25375620	15	+	27260156	HCC44	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.33155515627437826	[236]	[403,264,245,428]	5	hSpCas9	negative selection	6791267
25408612	25408635	15	+	27260156	HCC44	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.2607242049989711	[1026]	[978,1483,1899,1233]	4	hSpCas9	negative selection	6791268
25408622	25408645	15	-	27260156	HCC44	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.024132446954562375	[512]	[874,535,542,431]	0	hSpCas9	negative selection	6855515
25354352	25354375	15	-	27260156	HCC44	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.9609841233139571	[180]	[522,268,440,394]	9	hSpCas9	negative selection	6855516
25354352	25354375	15	+	27260156	HCC44	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.00047225573045328595	[791]	[902,911,779,957]	0	hSpCas9	negative selection	6855517
25375530	25375553	15	-	27260156	G402	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.9562599901499773	[10]	[0,0,0,9]	-9	hSpCas9	negative selection	6912517
25375597	25375620	15	+	27260156	G402	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.4347477876503778	[236]	[132,223,510,634]	5	hSpCas9	negative selection	6912518
25408612	25408635	15	+	27260156	G402	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.36792266994426415	[1026]	[1709,1635,1684,1453]	4	hSpCas9	negative selection	6912519
25408622	25408645	15	-	27260156	G402	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.09229229206527637	[512]	[530,707,332,1057]	1	hSpCas9	negative selection	6976766
25354352	25354375	15	-	27260156	G402	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.11242138597337137	[180]	[473,236,144,136]	1	hSpCas9	negative selection	6976767
25354352	25354375	15	+	27260156	G402	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.5676752673546874	[791]	[635,560,727,671]	-6	hSpCas9	negative selection	6976768
25375530	25375553	15	-	27260156	L33	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-2.4534059650287325	[10]	[1,0,0,1]	-9	hSpCas9	negative selection	7033768
25375597	25375620	15	+	27260156	L33	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.44070926949462175	[236]	[196,63,105,175]	-8	hSpCas9	negative selection	7033769
25408612	25408635	15	+	27260156	L33	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.21121840640183143	[1026]	[1028,549,777,1150]	4	hSpCas9	negative selection	7033770
25408622	25408645	15	-	27260156	L33	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.020115112339319202	[512]	[554,192,346,444]	0	hSpCas9	negative selection	7098017
25354352	25354375	15	-	27260156	L33	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.13074854857489093	[180]	[128,83,210,125]	3	hSpCas9	negative selection	7098018
25354352	25354375	15	+	27260156	L33	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.31629195135187294	[791]	[895,382,709,986]	6	hSpCas9	negative selection	7098019
25375530	25375553	15	-	27260156	K562	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.5195107646154185	[10]	[0,0,22,1]	-6	hSpCas9	negative selection	7155019
25375597	25375620	15	+	27260156	K562	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.03857280601125668	[236]	[163,237,250,207]	0	hSpCas9	negative selection	7155020
25408612	25408635	15	+	27260156	K562	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.6156495649244607	[1026]	[1623,1496,1238,1259]	7	hSpCas9	negative selection	7155021
25408622	25408645	15	-	27260156	K562	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.49821144711784093	[512]	[783,753,398,648]	6	hSpCas9	negative selection	7219268
25354352	25354375	15	-	27260156	K562	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.23628106333467191	[180]	[244,183,157,174]	3	hSpCas9	negative selection	7219269
25354352	25354375	15	+	27260156	K562	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.10618310143071541	[791]	[610,866,1010,551]	1	hSpCas9	negative selection	7219270
25375530	25375553	15	-	27260156	HT29	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.019315933978433897	[10]	[9,18,17,7]	0	hSpCas9	negative selection	7276270
25375597	25375620	15	+	27260156	HT29	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.10778536365694713	[236]	[243,386,200,397]	2	hSpCas9	negative selection	7276271
25408612	25408635	15	+	27260156	HT29	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.2877046007932107	[1026]	[1645,1775,1620,1122]	5	hSpCas9	negative selection	7276272
25408622	25408645	15	-	27260156	HT29	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.2590408448889212	[512]	[622,521,560,397]	-5	hSpCas9	negative selection	7340519
25354352	25354375	15	-	27260156	HT29	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.06599057768972205	[180]	[143,293,261,148]	-1	hSpCas9	negative selection	7340520
25354352	25354375	15	+	27260156	HT29	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.07739584304535219	[791]	[1224,1169,932,785]	1	hSpCas9	negative selection	7340521
25375530	25375553	15	-	27260156	MHHES1	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.3548598500842388	[10]	[0,6,0,8]	-9	hSpCas9	negative selection	7397521
25375597	25375620	15	+	27260156	MHHES1	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.13293101399316054	[236]	[323,231,180,239]	-2	hSpCas9	negative selection	7397522
25408612	25408635	15	+	27260156	MHHES1	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.5209692923816445	[1026]	[1970,2039,1557,1212]	8	hSpCas9	negative selection	7397523
25408622	25408645	15	-	27260156	MHHES1	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.37865517641805674	[512]	[495,517,381,395]	-6	hSpCas9	negative selection	7461770
25354352	25354375	15	-	27260156	MHHES1	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.12668048144771094	[180]	[301,175,136,148]	-2	hSpCas9	negative selection	7461771
25354352	25354375	15	+	27260156	MHHES1	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.008215658601866904	[791]	[1023,982,1012,601]	0	hSpCas9	negative selection	7461772
25375530	25375553	15	-	27260156	MEWO	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.8861441740877174	[10]	[0,3,2]	-9	hSpCas9	negative selection	7518772
25375597	25375620	15	+	27260156	MEWO	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.36442027182661785	[236]	[189,193,135]	-7	hSpCas9	negative selection	7518773
25408612	25408635	15	+	27260156	MEWO	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.05531212533167196	[1026]	[1044,984,973]	1	hSpCas9	negative selection	7518774
25408622	25408645	15	-	27260156	MEWO	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.06548506875953751	[512]	[432,430,506]	-1	hSpCas9	negative selection	7583021
25354352	25354375	15	-	27260156	MEWO	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.5642574828572796	[180]	[333,311,120]	9	hSpCas9	negative selection	7583022
25354352	25354375	15	+	27260156	MEWO	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.017146260306175276	[791]	[852,604,811]	0	hSpCas9	negative selection	7583023
25375530	25375553	15	-	27260156	LNCAPCLONEFGC	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-3.0340344737226914	[10]	[0,0,1,0]	-9	hSpCas9	negative selection	7640023
25375597	25375620	15	+	27260156	LNCAPCLONEFGC	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.4447725559804111	[236]	[302,314,258,284]	7	hSpCas9	negative selection	7640024
25408612	25408635	15	+	27260156	LNCAPCLONEFGC	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.4909528244096226	[1026]	[1589,1039,1387,1234]	7	hSpCas9	negative selection	7640025
25408622	25408645	15	-	27260156	LNCAPCLONEFGC	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.24567943752447702	[512]	[418,265,517,390]	-4	hSpCas9	negative selection	7704272
25354352	25354375	15	-	27260156	LNCAPCLONEFGC	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.16983378840441388	[180]	[162,211,229,137]	2	hSpCas9	negative selection	7704273
25354352	25354375	15	+	27260156	LNCAPCLONEFGC	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.02797675965247637	[791]	[621,613,934,684]	0	hSpCas9	negative selection	7704274
25375530	25375553	15	-	27260156	PANC0327	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-2.993452469680353	[10]	[1,0,0,0]	-9	hSpCas9	negative selection	7761274
25375597	25375620	15	+	27260156	PANC0327	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.23428138853655023	[236]	[168,142,335,71]	-3	hSpCas9	negative selection	7761275
25408612	25408635	15	+	27260156	PANC0327	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.7800503471385614	[1026]	[1539,1750,1150,1796]	9	hSpCas9	negative selection	7761276
25408622	25408645	15	-	27260156	PANC0327	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.28906981557299094	[512]	[372,268,341,520]	-4	hSpCas9	negative selection	7825523
25354352	25354375	15	-	27260156	PANC0327	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	1.2886409977511495	[180]	[417,213,783,180]	9	hSpCas9	negative selection	7825524
25354352	25354375	15	+	27260156	PANC0327	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.3618218181441637	[791]	[1020,684,974,972]	5	hSpCas9	negative selection	7825525
25375530	25375553	15	-	27260156	NCIH2009	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.2231899526906451	[10]	[105,4,10]	9	hSpCas9	negative selection	7882525
25375597	25375620	15	+	27260156	NCIH2009	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.26280657081013103	[236]	[339,389,449]	3	hSpCas9	negative selection	7882526
25408612	25408635	15	+	27260156	NCIH2009	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.29937672096300316	[1026]	[2152,1538,1682]	4	hSpCas9	negative selection	7882527
25408622	25408645	15	-	27260156	NCIH2009	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.0959184368275055	[512]	[1095,653,613]	1	hSpCas9	negative selection	7946774
25354352	25354375	15	-	27260156	NCIH2009	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.005270788420191241	[180]	[206,239,304]	0	hSpCas9	negative selection	7946775
25354352	25354375	15	+	27260156	NCIH2009	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.20080819019239593	[791]	[1328,1136,1360]	2	hSpCas9	negative selection	7946776
25375530	25375553	15	-	27260156	NCIH1373	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-2.8793219826901826	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	8003776
25375597	25375620	15	+	27260156	NCIH1373	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.09630584645357498	[236]	[179,214,455,70]	1	hSpCas9	negative selection	8003777
25408612	25408635	15	+	27260156	NCIH1373	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.19784172606766037	[1026]	[967,1082,1203,534]	2	hSpCas9	negative selection	8003778
25408622	25408645	15	-	27260156	NCIH1373	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.7503083668564685	[512]	[713,1293,823,251]	7	hSpCas9	negative selection	8068025
25354352	25354375	15	-	27260156	NCIH1373	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.06271652527643945	[180]	[375,187,162,37]	0	hSpCas9	negative selection	8068026
25354352	25354375	15	+	27260156	NCIH1373	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.037158975989055376	[791]	[723,911,860,295]	0	hSpCas9	negative selection	8068027
25375530	25375553	15	-	27260156	PATU8902	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.6586314387111933	[10]	[0,16,0,0]	-8	hSpCas9	negative selection	8125027
25375597	25375620	15	+	27260156	PATU8902	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.3525979468470821	[236]	[332,146,179,408]	-4	hSpCas9	negative selection	8125028
25408612	25408635	15	+	27260156	PATU8902	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.7542023286387416	[1026]	[2599,2585,1578,3170]	7	hSpCas9	negative selection	8125029
25408622	25408645	15	-	27260156	PATU8902	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.7320572681923423	[512]	[891,1654,788,1553]	7	hSpCas9	negative selection	8189276
25354352	25354375	15	-	27260156	PATU8902	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	-0.3133307432510286	[180]	[196,236,174,208]	-3	hSpCas9	negative selection	8189277
25354352	25354375	15	+	27260156	PATU8902	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.19732804924677483	[791]	[906,1304,588,1161]	-2	hSpCas9	negative selection	8189278
25375530	25375553	15	-	27260156	PANC1	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.6644921377245518	[10]	[8,10,0,3]	-7	hSpCas9	negative selection	8246278
25375597	25375620	15	+	27260156	PANC1	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.07772965784957142	[236]	[182,190,67,305]	-1	hSpCas9	negative selection	8246279
25408612	25408635	15	+	27260156	PANC1	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.5498306460598972	[1026]	[1351,1828,1262,877]	8	hSpCas9	negative selection	8246280
25408622	25408645	15	-	27260156	PANC1	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.0036501257716366198	[512]	[545,367,619,242]	0	hSpCas9	negative selection	8310527
25354352	25354375	15	-	27260156	PANC1	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.15133115741416403	[180]	[192,145,250,103]	2	hSpCas9	negative selection	8310528
25354352	25354375	15	+	27260156	PANC1	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.3524276262464656	[791]	[786,1127,714,880]	6	hSpCas9	negative selection	8310529
25375530	25375553	15	-	27260156	PANC0813	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-2.752425235655041	[10]	[4,0,0,0]	-9	hSpCas9	negative selection	8367529
25375597	25375620	15	+	27260156	PANC0813	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.10099660935353127	[236]	[356,283,378,185]	1	hSpCas9	negative selection	8367530
25408612	25408635	15	+	27260156	PANC0813	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.20869410678899358	[1026]	[1334,1248,1441,1534]	3	hSpCas9	negative selection	8367531
25408622	25408645	15	-	27260156	PANC0813	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.16471917658714413	[512]	[612,624,789,667]	2	hSpCas9	negative selection	8431778
25354352	25354375	15	-	27260156	PANC0813	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.06915343907678739	[180]	[243,189,307,155]	1	hSpCas9	negative selection	8431779
25354352	25354375	15	+	27260156	PANC0813	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.17846832720230565	[791]	[1510,881,979,887]	3	hSpCas9	negative selection	8431780
25375530	25375553	15	-	27260156	RDES	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.2660112379461186	[10]	[7,8,0,0]	-9	hSpCas9	negative selection	8488780
25375597	25375620	15	+	27260156	RDES	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.42195883727505223	[236]	[287,322,379,500]	6	hSpCas9	negative selection	8488781
25408612	25408635	15	+	27260156	RDES	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.3576132851511209	[1026]	[1218,1565,1636,1671]	6	hSpCas9	negative selection	8488782
25408622	25408645	15	-	27260156	RDES	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.2310050942560556	[512]	[552,556,879,830]	4	hSpCas9	negative selection	8553029
25354352	25354375	15	-	27260156	RDES	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.17261225745081332	[180]	[226,159,306,250]	3	hSpCas9	negative selection	8553030
25354352	25354375	15	+	27260156	RDES	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.0822331304682844	[791]	[728,1010,1013,1150]	1	hSpCas9	negative selection	8553031
25375530	25375553	15	-	27260156	PC3	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.5342058530190972	[10]	[0,0,9,22]	-8	hSpCas9	negative selection	8610031
25375597	25375620	15	+	27260156	PC3	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.08724231334427568	[236]	[92,235,249,367]	-2	hSpCas9	negative selection	8610032
25408612	25408635	15	+	27260156	PC3	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.059158585469311964	[1026]	[730,992,2025,922]	1	hSpCas9	negative selection	8610033
25408622	25408645	15	-	27260156	PC3	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.08656029998665188	[512]	[365,461,515,595]	-2	hSpCas9	negative selection	8674280
25354352	25354375	15	-	27260156	PC3	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.4831136561814021	[180]	[173,336,375,167]	8	hSpCas9	negative selection	8674281
25354352	25354375	15	+	27260156	PC3	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.027807732065424084	[791]	[479,755,1566,782]	0	hSpCas9	negative selection	8674282
25375530	25375553	15	-	27260156	PATU8988T	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.1783252064925103	[10]	[0,0,14,0]	-9	hSpCas9	negative selection	8731282
25375597	25375620	15	+	27260156	PATU8988T	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.422946832916702	[236]	[203,512,150,387]	7	hSpCas9	negative selection	8731283
25408612	25408635	15	+	27260156	PATU8988T	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.30579555481197995	[1026]	[1097,1505,1175,1146]	5	hSpCas9	negative selection	8731284
25408622	25408645	15	-	27260156	PATU8988T	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.24625081449099018	[512]	[808,497,374,670]	4	hSpCas9	negative selection	8795531
25354352	25354375	15	-	27260156	PATU8988T	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.1377282435213203	[180]	[91,269,177,240]	2	hSpCas9	negative selection	8795532
25354352	25354375	15	+	27260156	PATU8988T	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.08870206144016757	[791]	[718,835,801,907]	1	hSpCas9	negative selection	8795533
25375530	25375553	15	-	27260156	T47D	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.9188157158021655	[10]	[4,3,16,0]	-9	hSpCas9	negative selection	8852533
25375597	25375620	15	+	27260156	T47D	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.038732026912830175	[236]	[247,247,298,343]	0	hSpCas9	negative selection	8852534
25408612	25408635	15	+	27260156	T47D	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.24518285744266244	[1026]	[1414,1232,1491,1550]	5	hSpCas9	negative selection	8852535
25408622	25408645	15	-	27260156	T47D	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.16658842237124638	[512]	[612,531,479,504]	-4	hSpCas9	negative selection	8916782
25354352	25354375	15	-	27260156	T47D	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.21752494537098221	[180]	[220,286,207,261]	4	hSpCas9	negative selection	8916783
25354352	25354375	15	+	27260156	T47D	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.09532921651332793	[791]	[831,889,823,907]	-2	hSpCas9	negative selection	8916784
25375530	25375553	15	-	27260156	SU8686	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.0380109086068527	[10]	[0,2,7,10]	-8	hSpCas9	negative selection	8973784
25375597	25375620	15	+	27260156	SU8686	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	0.1096974270297012	[236]	[173,191,344,333]	1	hSpCas9	negative selection	8973785
25408612	25408635	15	+	27260156	SU8686	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.4282070809588274	[1026]	[983,1207,1763,1632]	7	hSpCas9	negative selection	8973786
25408622	25408645	15	-	27260156	SU8686	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.08530051166568384	[512]	[593,376,628,577]	1	hSpCas9	negative selection	9038033
25354352	25354375	15	-	27260156	SU8686	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.0946807547426074	[180]	[140,182,225,228]	1	hSpCas9	negative selection	9038034
25354352	25354375	15	+	27260156	SU8686	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.16497215521589592	[791]	[847,812,722,1188]	2	hSpCas9	negative selection	9038035
25375530	25375553	15	-	27260156	SKES1	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.7660878553457939	[10]	[1,1,8,10]	-9	hSpCas9	negative selection	9095035
25375597	25375620	15	+	27260156	SKES1	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.05932874342726402	[236]	[337,272,152,169]	-1	hSpCas9	negative selection	9095036
25408612	25408635	15	+	27260156	SKES1	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.22035822623024504	[1026]	[1438,1490,1122,823]	5	hSpCas9	negative selection	9095037
25408622	25408645	15	-	27260156	SKES1	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.20278722443613978	[512]	[642,727,549,467]	4	hSpCas9	negative selection	9159284
25354352	25354375	15	-	27260156	SKES1	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.29024293902525855	[180]	[240,158,205,264]	6	hSpCas9	negative selection	9159285
25354352	25354375	15	+	27260156	SKES1	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.16305961327362495	[791]	[1167,1089,687,674]	3	hSpCas9	negative selection	9159286
25375530	25375553	15	-	27260156	TOV112D	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-3.4610185090728205	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	9216286
25375597	25375620	15	+	27260156	TOV112D	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.06228937167402049	[236]	[185,375,149,229]	-1	hSpCas9	negative selection	9216287
25408612	25408635	15	+	27260156	TOV112D	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.17810560162804268	[1026]	[1270,1479,1081,913]	3	hSpCas9	negative selection	9216288
25408622	25408645	15	-	27260156	TOV112D	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	0.17760672395129956	[512]	[737,684,421,518]	3	hSpCas9	negative selection	9280535
25354352	25354375	15	-	27260156	TOV112D	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.14282409805246754	[180]	[110,143,253,267]	2	hSpCas9	negative selection	9280536
25354352	25354375	15	+	27260156	TOV112D	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.2134983844118452	[791]	[570,825,689,673]	-4	hSpCas9	negative selection	9280537
25375530	25375553	15	-	27260156	TC71	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-1.2718451109611317	[10]	[0,8,0,8]	-9	hSpCas9	negative selection	9337537
25375597	25375620	15	+	27260156	TC71	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.4149266136818386	[236]	[129,184,229,218]	-8	hSpCas9	negative selection	9337538
25408612	25408635	15	+	27260156	TC71	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.16700088863133078	[1026]	[1232,1259,1091,1371]	4	hSpCas9	negative selection	9337539
25408622	25408645	15	-	27260156	TC71	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.006226639998938938	[512]	[628,467,517,575]	0	hSpCas9	negative selection	9401786
25354352	25354375	15	-	27260156	TC71	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.18574752177641085	[180]	[194,228,254,201]	4	hSpCas9	negative selection	9401787
25354352	25354375	15	+	27260156	TC71	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	0.08084393892156838	[791]	[763,925,1013,885]	2	hSpCas9	negative selection	9401788
25375530	25375553	15	-	27260156	TC32	viability	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.10178438442770776	[10]	[26,7,4,0]	1	hSpCas9	negative selection	9458788
25375597	25375620	15	+	27260156	TC32	viability	CATTAATCTTATAAAGCTCGAGG	UBE3A	ENSG00000114062	-0.13137216372332206	[236]	[222,183,193,201]	-2	hSpCas9	negative selection	9458789
25408612	25408635	15	+	27260156	TC32	viability	TGGCTCACTTCCAATAACACTGG	UBE3A	ENSG00000114062	0.5405713201617552	[1026]	[1182,1303,1666,1488]	8	hSpCas9	negative selection	9458790
25408622	25408645	15	-	27260156	TC32	viability	AGAAGCTGCACCAGTGTTATTGG	UBE3A	ENSG00000114062	-0.18964432511465296	[512]	[376,263,656,478]	-3	hSpCas9	negative selection	9523037
25354352	25354375	15	-	27260156	TC32	viability	CCAGGGACTCTGTTCTGATTAGG	UBE3A	ENSG00000114062	0.3688055746250487	[180]	[221,248,146,220]	6	hSpCas9	negative selection	9523038
25354352	25354375	15	+	27260156	TC32	viability	CCTAATCAGAACAGAGTCCCTGG	UBE3A	ENSG00000114062	-0.07849911343818095	[791]	[622,450,982,887]	-1	hSpCas9	negative selection	9523039
25371024	25371047	15	-	27869803	HPAFII	viability after 27 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.4909816183860327	[524]	[400,376,NaN]	4	hSpCas9	negative selection	9553125
25375530	25375553	15	-	27869803	HPAFII	viability after 27 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	1.1647300465222958	[143]	[100,226,NaN]	8	hSpCas9	negative selection	9553126
25371024	25371047	15	-	27869803	HPAFII	viability after 15 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.21204373822420064	[524]	[832,541,NaN]	2	hSpCas9	negative selection	9635574
25375530	25375553	15	-	27869803	HPAFII	viability after 15 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.35611372841490907	[143]	[268,153,NaN]	4	hSpCas9	negative selection	9635575
25371024	25371047	15	-	27869803	ASPC1	viability after 36 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.582951768075805	[889]	[425,370,562]	6	hSpCas9	negative selection	9718023
25375530	25375553	15	-	27869803	ASPC1	viability after 36 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.5070701453604141	[332]	[150,200,144]	5	hSpCas9	negative selection	9718024
25371024	25371047	15	-	27869803	PATU8988S	viability after 35 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.4345595072230647	[751]	[332,485,NaN]	5	hSpCas9	negative selection	9800472
25375530	25375553	15	-	27869803	PATU8988S	viability after 35 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	-0.22090589104619496	[352]	[115,127,NaN]	-2	hSpCas9	negative selection	9800473
25371024	25371047	15	-	27869803	PATU8988S	viability after 31 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.5672443725198353	[751]	[310,613,NaN]	6	hSpCas9	negative selection	9882921
25375530	25375553	15	-	27869803	PATU8988S	viability after 31 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.0940714599911816	[352]	[151,147,NaN]	1	hSpCas9	negative selection	9882922
25371024	25371047	15	-	27869803	HPAFII	viability after 35 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.5122849054734777	[524]	[308,457,NaN]	3	hSpCas9	negative selection	9965370
25375530	25375553	15	-	27869803	HPAFII	viability after 35 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.8695025122742371	[143]	[40,236,NaN]	6	hSpCas9	negative selection	9965371
25371024	25371047	15	-	27869803	HPAFII	viability after 31 days	CTATGCAAATGTAGTGGGAGGGG	UBE3A	ENSG00000114062	0.5885698164274749	[524]	[410,477,NaN]	4	hSpCas9	negative selection	10047819
25375530	25375553	15	-	27869803	HPAFII	viability after 31 days	GCTTACCTTGAGAACTCGAAAGG	UBE3A	ENSG00000114062	0.758843221025502	[143]	[52,227,NaN]	5	hSpCas9	negative selection	10047820
25370882	25370905	15	+	28162770	P31FUJ	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.08733260864993292	[160]	[200]	0	hSpCas9	negative selection	10260493
25375504	25375527	15	+	28162770	P31FUJ	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.7980351995082144	[161]	[330]	8	hSpCas9	negative selection	10260494
25360442	25360465	15	-	28162770	P31FUJ	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	0.618054356279812	[111]	[201]	7	hSpCas9	negative selection	10260495
25371539	25371562	15	-	28162770	P31FUJ	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.09348375764555339	[594]	[745]	0	hSpCas9	negative selection	10260496
25375708	25375731	15	-	28162770	P31FUJ	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.06841538651349627	[173]	[194]	0	hSpCas9	negative selection	10260497
25371025	25371048	15	-	28162770	P31FUJ	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.7441878175391212	[157]	[310]	8	hSpCas9	negative selection	10260498
25370854	25370877	15	+	28162770	P31FUJ	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.14183294080382816	[171]	[222]	1	hSpCas9	negative selection	10260499
25360509	25360532	15	-	28162770	P31FUJ	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	0.2741577843055045	[75]	[107]	3	hSpCas9	negative selection	10260500
25375563	25375586	15	-	28162770	P31FUJ	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.4547474755020726	[1080]	[1740]	5	hSpCas9	negative selection	10260501
25354610	25354633	15	-	28162770	P31FUJ	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.7902322663997263	[465]	[946]	8	hSpCas9	negative selection	10260502
25370882	25370905	15	+	28162770	TF1	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10429859
25375504	25375527	15	+	28162770	TF1	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10429860
25360442	25360465	15	-	28162770	TF1	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10429861
25371539	25371562	15	-	28162770	TF1	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	NaN	[NaN]	[529]	1	hSpCas9	negative selection	10429862
25375708	25375731	15	-	28162770	TF1	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10429863
25371025	25371048	15	-	28162770	TF1	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10429864
25370854	25370877	15	+	28162770	TF1	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10429865
25360509	25360532	15	-	28162770	TF1	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10429866
25375563	25375586	15	-	28162770	TF1	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	NaN	[NaN]	[1485]	1	hSpCas9	negative selection	10429867
25354610	25354633	15	-	28162770	TF1	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	NaN	[NaN]	[561]	1	hSpCas9	negative selection	10429868
25370882	25370905	15	+	28162770	SKM1	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10599225
25375504	25375527	15	+	28162770	SKM1	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10599226
25360442	25360465	15	-	28162770	SKM1	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	1.1458178962288448	[33]	[132]	9	hSpCas9	negative selection	10599227
25371539	25371562	15	-	28162770	SKM1	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.5623669716412638	[207]	[542]	5	hSpCas9	negative selection	10599228
25375708	25375731	15	-	28162770	SKM1	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	1.5105736410648654	[53]	[271]	9	hSpCas9	negative selection	10599229
25371025	25371048	15	-	28162770	SKM1	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	1.2357137998342818	[48]	[203]	9	hSpCas9	negative selection	10599230
25370854	25370877	15	+	28162770	SKM1	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.28605804783544736	[44]	[96]	2	hSpCas9	negative selection	10599231
25360509	25360532	15	-	28162770	SKM1	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10599232
25375563	25375586	15	-	28162770	SKM1	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.2794260348701174	[253]	[544]	2	hSpCas9	negative selection	10599233
25354610	25354633	15	-	28162770	SKM1	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	1.3849606827448362	[93]	[433]	9	hSpCas9	negative selection	10599234
25370882	25370905	15	+	28162770	SKM1	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.10697865673647636	[52]	[86]	-1	hSpCas9	negative selection	10768591
25375504	25375527	15	+	28162770	SKM1	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.11088410611945757	[43]	[83]	1	hSpCas9	negative selection	10768592
25360442	25360465	15	-	28162770	SKM1	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	1.1458178962288448	[33]	[132]	9	hSpCas9	negative selection	10768593
25371539	25371562	15	-	28162770	SKM1	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.5623669716412638	[207]	[542]	5	hSpCas9	negative selection	10768594
25375708	25375731	15	-	28162770	SKM1	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	1.5105736410648654	[53]	[271]	9	hSpCas9	negative selection	10768595
25371025	25371048	15	-	28162770	SKM1	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	1.2357137998342818	[48]	[203]	9	hSpCas9	negative selection	10768596
25370854	25370877	15	+	28162770	SKM1	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.28605804783544736	[44]	[96]	2	hSpCas9	negative selection	10768597
25360509	25360532	15	-	28162770	SKM1	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.08503610385579918	[20]	[34]	0	hSpCas9	negative selection	10768598
25375563	25375586	15	-	28162770	SKM1	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.2794260348701174	[253]	[544]	2	hSpCas9	negative selection	10768599
25354610	25354633	15	-	28162770	SKM1	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	1.3849606827448362	[93]	[433]	9	hSpCas9	negative selection	10768600
25370882	25370905	15	+	28162770	PL21	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.7034306228275871	[216]	[57]	-5	hSpCas9	negative selection	10937957
25375504	25375527	15	+	28162770	PL21	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	1.2781421264905932	[143]	[151]	9	hSpCas9	negative selection	10937958
25360442	25360465	15	-	28162770	PL21	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.2193992770244645	[106]	[39]	-1	hSpCas9	negative selection	10937959
25371539	25371562	15	-	28162770	PL21	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.5550305750544766	[637]	[188]	-4	hSpCas9	negative selection	10937960
25375708	25375731	15	-	28162770	PL21	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-1.9195996297847753	[225]	[25]	-8	hSpCas9	negative selection	10937961
25371025	25371048	15	-	28162770	PL21	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.4480671279329057	[191]	[113]	4	hSpCas9	negative selection	10937962
25370854	25370877	15	+	28162770	PL21	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	1.1297502865979223	[125]	[119]	8	hSpCas9	negative selection	10937963
25360509	25360532	15	-	28162770	PL21	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.6623568617607449	[39]	[10]	-4	hSpCas9	negative selection	10937964
25375563	25375586	15	-	28162770	PL21	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.41750936363825586	[780]	[453]	3	hSpCas9	negative selection	10937965
25354610	25354633	15	-	28162770	PL21	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.27169287551435417	[294]	[154]	2	hSpCas9	negative selection	10937966
25370882	25370905	15	+	28162770	P31FUJ	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.08733260864993292	[160]	[200]	0	hSpCas9	negative selection	11107323
25375504	25375527	15	+	28162770	P31FUJ	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.7980351995082144	[161]	[330]	8	hSpCas9	negative selection	11107324
25360442	25360465	15	-	28162770	P31FUJ	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	0.618054356279812	[111]	[201]	7	hSpCas9	negative selection	11107325
25371539	25371562	15	-	28162770	P31FUJ	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.09348375764555339	[594]	[745]	0	hSpCas9	negative selection	11107326
25375708	25375731	15	-	28162770	P31FUJ	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.06841538651349627	[173]	[194]	0	hSpCas9	negative selection	11107327
25371025	25371048	15	-	28162770	P31FUJ	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.7441878175391212	[157]	[310]	8	hSpCas9	negative selection	11107328
25370854	25370877	15	+	28162770	P31FUJ	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.14183294080382816	[171]	[222]	1	hSpCas9	negative selection	11107329
25360509	25360532	15	-	28162770	P31FUJ	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	0.2741577843055045	[75]	[107]	3	hSpCas9	negative selection	11107330
25375563	25375586	15	-	28162770	P31FUJ	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.4547474755020726	[1080]	[1740]	5	hSpCas9	negative selection	11107331
25354610	25354633	15	-	28162770	P31FUJ	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.7902322663997263	[465]	[946]	8	hSpCas9	negative selection	11107332
25370882	25370905	15	+	28162770	OCIAML5	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.532129773795726	[144]	[180]	-4	hSpCas9	negative selection	11276689
25375504	25375527	15	+	28162770	OCIAML5	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	1.444326431916228	[56]	[279]	9	hSpCas9	negative selection	11276690
25360442	25360465	15	-	28162770	OCIAML5	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	0.6853675597745732	[71]	[208]	6	hSpCas9	negative selection	11276691
25371539	25371562	15	-	28162770	OCIAML5	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.24911832466947836	[371]	[564]	-2	hSpCas9	negative selection	11276692
25375708	25375731	15	-	28162770	OCIAML5	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.3547849995766728	[119]	[276]	3	hSpCas9	negative selection	11276693
25371025	25371048	15	-	28162770	OCIAML5	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	-0.6751888087799178	[91]	[103]	-4	hSpCas9	negative selection	11276694
25370854	25370877	15	+	28162770	OCIAML5	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.626774259021754	[70]	[82]	-4	hSpCas9	negative selection	11276695
25360509	25360532	15	-	28162770	OCIAML5	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.4535171943737222	[21]	[28]	-3	hSpCas9	negative selection	11276696
25375563	25375586	15	-	28162770	OCIAML5	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.5556661277916137	[593]	[1575]	5	hSpCas9	negative selection	11276697
25354610	25354633	15	-	28162770	OCIAML5	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.5961377923500462	[257]	[703]	5	hSpCas9	negative selection	11276698
25370882	25370905	15	+	28162770	EOL1	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.5220633226347753	[266]	[201]	5	hSpCas9	negative selection	11446055
25375504	25375527	15	+	28162770	EOL1	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.18441489832564517	[151]	[90]	1	hSpCas9	negative selection	11446056
25360442	25360465	15	-	28162770	EOL1	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.5078369712722061	[250]	[92]	-4	hSpCas9	negative selection	11446057
25371539	25371562	15	-	28162770	EOL1	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.6757626934840577	[1133]	[373]	-5	hSpCas9	negative selection	11446058
25375708	25375731	15	-	28162770	EOL1	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.8609477165233302	[392]	[113]	-6	hSpCas9	negative selection	11446059
25371025	25371048	15	-	28162770	EOL1	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.37820656487668575	[386]	[264]	3	hSpCas9	negative selection	11446060
25370854	25370877	15	+	28162770	EOL1	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.19062263172437943	[157]	[94]	1	hSpCas9	negative selection	11446061
25360509	25360532	15	-	28162770	EOL1	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.8033726829926646	[52]	[15]	-5	hSpCas9	negative selection	11446062
25375563	25375586	15	-	28162770	EOL1	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.11244643591166703	[1105]	[538]	-1	hSpCas9	negative selection	11446063
25354610	25354633	15	-	28162770	EOL1	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.7265076013473513	[420]	[366]	6	hSpCas9	negative selection	11446064
25370882	25370905	15	+	28162770	MOLM13	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	1.0324404222427745	[260]	[385]	7	hSpCas9	negative selection	11615421
25375504	25375527	15	+	28162770	MOLM13	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.1347751209100364	[163]	[107]	-1	hSpCas9	negative selection	11615422
25360442	25360465	15	-	28162770	MOLM13	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.30262877233265384	[173]	[101]	-2	hSpCas9	negative selection	11615423
25371539	25371562	15	-	28162770	MOLM13	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.4158671691962965	[959]	[925]	3	hSpCas9	negative selection	11615424
25375708	25375731	15	-	28162770	MOLM13	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.04494668418038883	[243]	[181]	0	hSpCas9	negative selection	11615425
25371025	25371048	15	-	28162770	MOLM13	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.029147621674466606	[224]	[165]	0	hSpCas9	negative selection	11615426
25370854	25370877	15	+	28162770	MOLM13	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.5893528940302459	[147]	[160]	4	hSpCas9	negative selection	11615427
25360509	25360532	15	-	28162770	MOLM13	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	2.0793240936269264	[53]	[164]	9	hSpCas9	negative selection	11615428
25375563	25375586	15	-	28162770	MOLM13	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.42571552331371465	[1188]	[639]	-3	hSpCas9	negative selection	11615429
25354610	25354633	15	-	28162770	MOLM13	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.5676336726999186	[460]	[493]	4	hSpCas9	negative selection	11615430
25370882	25370905	15	+	28162770	HEL	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.2028455404792021	[238]	[132]	-1	hSpCas9	negative selection	11784787
25375504	25375527	15	+	28162770	HEL	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.7117939283189331	[178]	[69]	-4	hSpCas9	negative selection	11784788
25360442	25360465	15	-	28162770	HEL	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	0.21464517989606696	[147]	[109]	1	hSpCas9	negative selection	11784789
25371539	25371562	15	-	28162770	HEL	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.7414612633558941	[863]	[330]	-5	hSpCas9	negative selection	11784790
25375708	25375731	15	-	28162770	HEL	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.33820087398706367	[267]	[216]	3	hSpCas9	negative selection	11784791
25371025	25371048	15	-	28162770	HEL	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.6672959362443358	[232]	[236]	6	hSpCas9	negative selection	11784792
25370854	25370877	15	+	28162770	HEL	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-0.040404062659702644	[113]	[70]	0	hSpCas9	negative selection	11784793
25360509	25360532	15	-	28162770	HEL	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	0.5240943355017378	[37]	[34]	4	hSpCas9	negative selection	11784794
25375563	25375586	15	-	28162770	HEL	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.11231307048701877	[1096]	[649]	-1	hSpCas9	negative selection	11784795
25354610	25354633	15	-	28162770	HEL	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.968924760890876	[405]	[508]	8	hSpCas9	negative selection	11784796
25370882	25370905	15	+	28162770	MV411	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	0.6918496521951327	[157]	[214]	6	hSpCas9	negative selection	11954153
25375504	25375527	15	+	28162770	MV411	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.12179625888294368	[154]	[119]	-1	hSpCas9	negative selection	11954154
25360442	25360465	15	-	28162770	MV411	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-2.1585548088930615	[105]	[19]	-8	hSpCas9	negative selection	11954155
25371539	25371562	15	-	28162770	MV411	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.17924548551481	[538]	[400]	-1	hSpCas9	negative selection	11954156
25375708	25375731	15	-	28162770	MV411	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-1.852098122768139	[179]	[41]	-8	hSpCas9	negative selection	11954157
25371025	25371048	15	-	28162770	MV411	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	-0.000999478838060612	[176]	[148]	0	hSpCas9	negative selection	11954158
25370854	25370877	15	+	28162770	MV411	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.2900818881912691	[99]	[102]	2	hSpCas9	negative selection	11954159
25360509	25360532	15	-	28162770	MV411	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-2.1151325286019333	[35]	[6]	-8	hSpCas9	negative selection	11954160
25375563	25375586	15	-	28162770	MV411	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.1362807430697861	[804]	[616]	-1	hSpCas9	negative selection	11954161
25354610	25354633	15	-	28162770	MV411	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.7022525413497026	[312]	[428]	6	hSpCas9	negative selection	11954162
25370882	25370905	15	+	28162770	MONOMAC1	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.4080245051237522	[146]	[126]	-4	hSpCas9	negative selection	12123519
25375504	25375527	15	+	28162770	MONOMAC1	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	-0.34678396656423593	[70]	[63]	-3	hSpCas9	negative selection	12123520
25360442	25360465	15	-	28162770	MONOMAC1	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.739564081460313	[66]	[45]	-6	hSpCas9	negative selection	12123521
25371539	25371562	15	-	28162770	MONOMAC1	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.5495532617803391	[428]	[335]	-5	hSpCas9	negative selection	12123522
25375708	25375731	15	-	28162770	MONOMAC1	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-0.9419952319792904	[180]	[107]	-6	hSpCas9	negative selection	12123523
25371025	25371048	15	-	28162770	MONOMAC1	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.23359750727030842	[137]	[185]	2	hSpCas9	negative selection	12123524
25370854	25370877	15	+	28162770	MONOMAC1	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	0.02019386916111532	[79]	[92]	0	hSpCas9	negative selection	12123525
25360509	25360532	15	-	28162770	MONOMAC1	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-1.584059970168801	[33]	[12]	-8	hSpCas9	negative selection	12123526
25375563	25375586	15	-	28162770	MONOMAC1	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	-0.1465041130405602	[532]	[551]	-1	hSpCas9	negative selection	12123527
25354610	25354633	15	-	28162770	MONOMAC1	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.03349491908691071	[201]	[236]	0	hSpCas9	negative selection	12123528
25370882	25370905	15	+	28162770	OCIAML2	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.07009189565843249	[24]	[131]	0	hSpCas9	negative selection	12292885
25375504	25375527	15	+	28162770	OCIAML2	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	1.2646954105427894	[21]	[292]	9	hSpCas9	negative selection	12292886
25360442	25360465	15	-	28162770	OCIAML2	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	-0.4831207694253582	[28]	[114]	-4	hSpCas9	negative selection	12292887
25371539	25371562	15	-	28162770	OCIAML2	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	0.4413139980926426	[94]	[714]	4	hSpCas9	negative selection	12292888
25375708	25375731	15	-	28162770	OCIAML2	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	-1.1926450779423958	[39]	[96]	-7	hSpCas9	negative selection	12292889
25371025	25371048	15	-	28162770	OCIAML2	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.6534914865870264	[31]	[278]	6	hSpCas9	negative selection	12292890
25370854	25370877	15	+	28162770	OCIAML2	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-1.6722636864118114	[22]	[39]	-7	hSpCas9	negative selection	12292891
25360509	25360532	15	-	28162770	OCIAML2	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.470629825242161	[8]	[35]	-4	hSpCas9	negative selection	12292892
25375563	25375586	15	-	28162770	OCIAML2	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.40745280750208	[144]	[1065]	4	hSpCas9	negative selection	12292893
25354610	25354633	15	-	28162770	OCIAML2	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.782188184548496	[61]	[590]	7	hSpCas9	negative selection	12292894
25370882	25370905	15	+	28162770	OCIAML3	viability	ACACCAAGTTCAGTTTCCAGGGG	UBE3A	ENSG00000114062	-0.4150374992788438	[52]	[119]	-3	hSpCas9	negative selection	12462251
25375504	25375527	15	+	28162770	OCIAML3	viability	TCTCAGAGCAGGAGTTGTTGGGG	UBE3A	ENSG00000114062	0.0874628412503394	[52]	[169]	0	hSpCas9	negative selection	12462252
25360442	25360465	15	-	28162770	OCIAML3	viability	GGAGAACAAGGAGTTGATGAGGG	UBE3A	ENSG00000114062	1.0369672581538294	[35]	[222]	8	hSpCas9	negative selection	12462253
25371539	25371562	15	-	28162770	OCIAML3	viability	GAAGCATCTTCCTCAAGGATAGG	UBE3A	ENSG00000114062	-0.2942185227060494	[196]	[484]	-2	hSpCas9	negative selection	12462254
25375708	25375731	15	-	28162770	OCIAML3	viability	CTACTACCACCAGTTAACTGAGG	UBE3A	ENSG00000114062	0.3551681005981544	[64]	[250]	3	hSpCas9	negative selection	12462255
25371025	25371048	15	-	28162770	OCIAML3	viability	ACTATGCAAATGTAGTGGGAGGG	UBE3A	ENSG00000114062	0.22799405769784242	[55]	[197]	2	hSpCas9	negative selection	12462256
25370854	25370877	15	+	28162770	OCIAML3	viability	AAGTGGTTTTCGACAATCCAGGG	UBE3A	ENSG00000114062	-1.352999540820368	[32]	[38]	-7	hSpCas9	negative selection	12462257
25360509	25360532	15	-	28162770	OCIAML3	viability	CTAGCTAGAGATGATCGCTATGG	UBE3A	ENSG00000114062	-0.5600603084008258	[20]	[42]	-4	hSpCas9	negative selection	12462258
25375563	25375586	15	-	28162770	OCIAML3	viability	GATCCTCATCCCTCCAAGAAAGG	UBE3A	ENSG00000114062	0.7512844476287097	[244]	[1244]	6	hSpCas9	negative selection	12462259
25354610	25354633	15	-	28162770	OCIAML3	viability	CAGTTCAAGGCTTTTCGGAGAGG	UBE3A	ENSG00000114062	0.1660415669550842	[92]	[314]	1	hSpCas9	negative selection	12462260