Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 197131
• Symbol: UBR1
• Description: ubiquitin protein ligase E3 component n-recognin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/UBR1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
42976824	42976847	15	+	26472758	Jiyoye	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.27472508548222396	[170]	[155]	2	hSpCas9	negative selection	176770
42976804	42976827	15	+	26472758	Jiyoye	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	1.8612070124005808	[72]	[199]	8	hSpCas9	negative selection	176771
43105974	43105997	15	-	26472758	Jiyoye	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.2410612940660013	[267]	[170]	-2	hSpCas9	negative selection	176772
43075036	43075059	15	-	26472758	Jiyoye	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	4.407175381505873	[0]	[15]	9	hSpCas9	negative selection	176773
43047244	43047267	15	-	26472758	Jiyoye	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.32246687185447376	[261]	[157]	-2	hSpCas9	negative selection	176774
43030024	43030047	15	-	26472758	Jiyoye	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.07825144566436859	[55]	[39]	0	hSpCas9	negative selection	176775
43024950	43024973	15	+	26472758	Jiyoye	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	0.1501647632998494	[238]	[199]	1	hSpCas9	negative selection	176776
43007260	43007283	15	+	26472758	Jiyoye	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.7585250340747136	[340]	[151]	-5	hSpCas9	negative selection	176777
43003867	43003890	15	-	26472758	Jiyoye	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.3404374568598411	[135]	[80]	-2	hSpCas9	negative selection	176778
42977893	42977916	15	+	26472758	Jiyoye	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.531424073829983	[22]	[5]	-7	hSpCas9	negative selection	176779
42976824	42976847	15	+	26472758	KBM7	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.14174970387756647	[433,642]	[297,178]	-1	hSpCas9	negative selection	367888
42976804	42976827	15	+	26472758	KBM7	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.7037153354859433	[713,576]	[427,547]	7	hSpCas9	negative selection	367889
43105974	43105997	15	-	26472758	KBM7	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.059238475925714296	[1072,657]	[280,473]	0	hSpCas9	negative selection	367890
43075036	43075059	15	-	26472758	KBM7	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	0.15004071184691314	[89,60]	[32,43]	1	hSpCas9	negative selection	367891
43047244	43047267	15	-	26472758	KBM7	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.11599436089527981	[1603,932]	[525,548]	-1	hSpCas9	negative selection	367892
43030024	43030047	15	-	26472758	KBM7	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.9477109343247543	[234,161]	[71,25]	-6	hSpCas9	negative selection	367893
43024950	43024973	15	+	26472758	KBM7	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.3224920590557442	[1317,887]	[389,424]	-3	hSpCas9	negative selection	367894
43007260	43007283	15	+	26472758	KBM7	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.010699787185694865	[1024,884]	[494,411]	0	hSpCas9	negative selection	367895
43003867	43003890	15	-	26472758	KBM7	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.5304053068686413	[491,419]	[157,138]	-5	hSpCas9	negative selection	367896
42977893	42977916	15	+	26472758	KBM7	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-0.5064327683425902	[60,71]	[25,18]	-4	hSpCas9	negative selection	367897
42976824	42976847	15	+	26472758	Raji	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.30002861331599556	[251]	[71]	3	hSpCas9	negative selection	559006
42976804	42976827	15	+	26472758	Raji	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.30468497574721687	[463]	[132]	3	hSpCas9	negative selection	559007
43105974	43105997	15	-	26472758	Raji	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	1.0510455512237875	[234]	[112]	8	hSpCas9	negative selection	559008
43075036	43075059	15	-	26472758	Raji	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-1.2145445595137625	[39]	[3]	-7	hSpCas9	negative selection	559009
43047244	43047267	15	-	26472758	Raji	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.08013350096539895	[480]	[117]	0	hSpCas9	negative selection	559010
43030024	43030047	15	-	26472758	Raji	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	0.410310668330906	[106]	[32]	4	hSpCas9	negative selection	559011
43024950	43024973	15	+	26472758	Raji	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.984920568946239	[596]	[34]	-8	hSpCas9	negative selection	559012
43007260	43007283	15	+	26472758	Raji	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.2611557216717053	[488]	[135]	2	hSpCas9	negative selection	559013
43003867	43003890	15	-	26472758	Raji	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.4466535270344786	[214]	[67]	4	hSpCas9	negative selection	559014
42977893	42977916	15	+	26472758	Raji	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.750597459753973	[28]	[1]	-8	hSpCas9	negative selection	559015
42976824	42976847	15	+	26472758	K562	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.4497728428094678	[575]	[355]	-3	hSpCas9	negative selection	750124
42976804	42976827	15	+	26472758	K562	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.49268568545673497	[670]	[796]	4	hSpCas9	negative selection	750125
43105974	43105997	15	-	26472758	K562	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.15128228651479758	[666]	[506]	-1	hSpCas9	negative selection	750126
43075036	43075059	15	-	26472758	K562	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-3.7999753916920067	[32]	[1]	-9	hSpCas9	negative selection	750127
43047244	43047267	15	-	26472758	K562	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.468689250861821	[986]	[1152]	4	hSpCas9	negative selection	750128
43030024	43030047	15	-	26472758	K562	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.2440809335534182	[187]	[133]	-2	hSpCas9	negative selection	750129
43024950	43024973	15	+	26472758	K562	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.1654570664966184	[929]	[349]	-6	hSpCas9	negative selection	750130
43007260	43007283	15	+	26472758	K562	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.6815023329725487	[827]	[1120]	5	hSpCas9	negative selection	750131
43003867	43003890	15	-	26472758	K562	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.032690863379069846	[308]	[254]	0	hSpCas9	negative selection	750132
42977893	42977916	15	+	26472758	K562	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	0.19319340431127352	[85]	[82]	1	hSpCas9	negative selection	750133
43054776	43054799	15	+	26627737	DLD1	viability	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	1.5605801100377397	[88]	[89,68,85]	9	hSpCas9	negative selection	790667
43060092	43060115	15	-	26627737	DLD1	viability	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.7370775022062007	[283]	[140,118,177]	7	hSpCas9	negative selection	790668
43067906	43067929	15	+	26627737	DLD1	viability	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.9354690238075541	[591]	[181,540,347]	8	hSpCas9	negative selection	790669
43070898	43070921	15	-	26627737	DLD1	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.3903937699811617	[935]	[389,264,475]	4	hSpCas9	negative selection	790670
43075067	43075090	15	-	26627737	DLD1	viability	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.5296335143931762	[457]	[206,217,196]	5	hSpCas9	negative selection	790671
43106010	43106033	15	-	26627737	DLD1	viability	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.8977807707712858	[233]	[191,122,98]	8	hSpCas9	negative selection	790672
43054776	43054799	15	+	26627737	GBM cells	viability after 5 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.30919432044451467	[133]	[68,46]	-5	hSpCas9	negative selection	872982
43060092	43060115	15	-	26627737	GBM cells	viability after 5 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.01862396492234142	[186]	[94,102]	0	hSpCas9	negative selection	872983
43067906	43067929	15	+	26627737	GBM cells	viability after 5 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.00038151396252716907	[397]	[207,218]	0	hSpCas9	negative selection	872984
43070898	43070921	15	-	26627737	GBM cells	viability after 5 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.12362016206038007	[622]	[336,390]	2	hSpCas9	negative selection	872985
43075067	43075090	15	-	26627737	GBM cells	viability after 5 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.30444535428816016	[250]	[117,99]	-5	hSpCas9	negative selection	872986
43106010	43106033	15	-	26627737	GBM cells	viability after 5 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.08996216789375207	[225]	[129,127]	1	hSpCas9	negative selection	872987
43054776	43054799	15	+	26627737	GBM cells	viability after 13 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.33186969381497144	[133]	[70,46]	-4	hSpCas9	negative selection	955297
43060092	43060115	15	-	26627737	GBM cells	viability after 13 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.27159017994022955	[186]	[120,53]	-3	hSpCas9	negative selection	955298
43067906	43067929	15	+	26627737	GBM cells	viability after 13 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.09258192027659207	[397]	[264,201]	1	hSpCas9	negative selection	955299
43070898	43070921	15	-	26627737	GBM cells	viability after 13 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.17460845629613786	[622]	[320,281]	-2	hSpCas9	negative selection	955300
43075067	43075090	15	-	26627737	GBM cells	viability after 13 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.21030630909697554	[250]	[172,144]	2	hSpCas9	negative selection	955301
43106010	43106033	15	-	26627737	GBM cells	viability after 13 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.040675233453262905	[225]	[132,107]	0	hSpCas9	negative selection	955302
43054776	43054799	15	+	26627737	GBM cells	viability after 21 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.08155505801699858	[133]	[87,66]	0	hSpCas9	negative selection	1037612
43060092	43060115	15	-	26627737	GBM cells	viability after 21 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.8783234643847464	[186]	[48,60]	-6	hSpCas9	negative selection	1037613
43067906	43067929	15	+	26627737	GBM cells	viability after 21 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.4279657144407031	[397]	[178,143]	-4	hSpCas9	negative selection	1037614
43070898	43070921	15	-	26627737	GBM cells	viability after 21 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.061304928350080834	[622]	[372,334]	0	hSpCas9	negative selection	1037615
43075067	43075090	15	-	26627737	GBM cells	viability after 21 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.08705857132466284	[250]	[142,114]	-1	hSpCas9	negative selection	1037616
43106010	43106033	15	-	26627737	GBM cells	viability after 21 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.11099821024756701	[225]	[120,106]	-1	hSpCas9	negative selection	1037617
43054776	43054799	15	+	26627737	RPE1	viability after 9 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.2103831049231233	[215]	[72,84]	1	hSpCas9	negative selection	1119927
43060092	43060115	15	-	26627737	RPE1	viability after 9 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-1.5163238040855689	[835]	[56,135]	-8	hSpCas9	negative selection	1119928
43067906	43067929	15	+	26627737	RPE1	viability after 9 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.540001003128703	[1329]	[528,703]	3	hSpCas9	negative selection	1119929
43070898	43070921	15	-	26627737	RPE1	viability after 9 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.3772821178221033	[2327]	[430,728]	-3	hSpCas9	negative selection	1119930
43075067	43075090	15	-	26627737	RPE1	viability after 9 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	1.3757148069924061	[309]	[298,190]	7	hSpCas9	negative selection	1119931
43106010	43106033	15	-	26627737	RPE1	viability after 9 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.029348656371993576	[1125]	[271,472]	0	hSpCas9	negative selection	1119932
43054776	43054799	15	+	26627737	RPE1	viability after 12 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.36326365157506024	[215]	[48,40]	-2	hSpCas9	negative selection	1202242
43060092	43060115	15	-	26627737	RPE1	viability after 12 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-1.0239048151414756	[835]	[91,129]	-6	hSpCas9	negative selection	1202243
43067906	43067929	15	+	26627737	RPE1	viability after 12 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.013270772392544483	[1329]	[364,355]	0	hSpCas9	negative selection	1202244
43070898	43070921	15	-	26627737	RPE1	viability after 12 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.6901264936169134	[2327]	[290,489]	-5	hSpCas9	negative selection	1202245
43075067	43075090	15	-	26627737	RPE1	viability after 12 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	1.615148449462519	[309]	[327,177]	8	hSpCas9	negative selection	1202246
43106010	43106033	15	-	26627737	RPE1	viability after 12 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.046107027171148784	[1125]	[272,353]	0	hSpCas9	negative selection	1202247
43054776	43054799	15	+	26627737	RPE1	viability after 15 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.23274603448713638	[215]	[54,87]	1	hSpCas9	negative selection	1284557
43060092	43060115	15	-	26627737	RPE1	viability after 15 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-1.8180116413232548	[835]	[34,97]	-8	hSpCas9	negative selection	1284558
43067906	43067929	15	+	26627737	RPE1	viability after 15 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.37906978816502734	[1329]	[641,341]	2	hSpCas9	negative selection	1284559
43070898	43070921	15	-	26627737	RPE1	viability after 15 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.741149210246193	[2327]	[366,419]	-5	hSpCas9	negative selection	1284560
43075067	43075090	15	-	26627737	RPE1	viability after 15 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.9384081040290084	[309]	[164,170]	5	hSpCas9	negative selection	1284561
43106010	43106033	15	-	26627737	RPE1	viability after 15 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.6355233280353828	[1125]	[174,233]	-4	hSpCas9	negative selection	1284562
43054776	43054799	15	+	26627737	RPE1	viability after 18 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.2489752834958614	[215]	[35,62]	-1	hSpCas9	negative selection	1366872
43060092	43060115	15	-	26627737	RPE1	viability after 18 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-1.0893834457017442	[835]	[33,182]	-6	hSpCas9	negative selection	1366873
43067906	43067929	15	+	26627737	RPE1	viability after 18 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.31684876346646207	[1329]	[463,428]	2	hSpCas9	negative selection	1366874
43070898	43070921	15	-	26627737	RPE1	viability after 18 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.8031450805208532	[2327]	[346,373]	-5	hSpCas9	negative selection	1366875
43075067	43075090	15	-	26627737	RPE1	viability after 18 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	1.3534444143018411	[309]	[308,111]	7	hSpCas9	negative selection	1366876
43106010	43106033	15	-	26627737	RPE1	viability after 18 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-1.0187776841009557	[1125]	[119,181]	-6	hSpCas9	negative selection	1366877
43054776	43054799	15	+	26627737	HeLa	viability after 8 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.8313534706300809	[109]	[62,3,21]	-7	hSpCas9	negative selection	1449187
43060092	43060115	15	-	26627737	HeLa	viability after 8 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.23646280497656336	[253]	[221,75,113]	2	hSpCas9	negative selection	1449188
43067906	43067929	15	+	26627737	HeLa	viability after 8 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.01317985259445753	[604]	[253,282,257]	0	hSpCas9	negative selection	1449189
43070898	43070921	15	-	26627737	HeLa	viability after 8 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.2675048799468771	[1099]	[437,383,380]	-3	hSpCas9	negative selection	1449190
43075067	43075090	15	-	26627737	HeLa	viability after 8 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-1.0547281247709646	[609]	[161,117,111]	-8	hSpCas9	negative selection	1449191
43106010	43106033	15	-	26627737	HeLa	viability after 8 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.11449923473098826	[431]	[147,248,121]	-1	hSpCas9	negative selection	1449192
43054776	43054799	15	+	26627737	HeLa	viability after 12 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.32372453036204263	[109]	[89,62,17]	3	hSpCas9	negative selection	1531502
43060092	43060115	15	-	26627737	HeLa	viability after 12 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.5083676242938862	[253]	[142,146,157]	4	hSpCas9	negative selection	1531503
43067906	43067929	15	+	26627737	HeLa	viability after 12 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.6506340139923794	[604]	[451,290,446]	5	hSpCas9	negative selection	1531504
43070898	43070921	15	-	26627737	HeLa	viability after 12 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.21162441107222318	[1099]	[479,309,398]	-2	hSpCas9	negative selection	1531505
43075067	43075090	15	-	26627737	HeLa	viability after 12 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.36651265680908235	[609]	[337,145,111]	-3	hSpCas9	negative selection	1531506
43106010	43106033	15	-	26627737	HeLa	viability after 12 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.49206380150132867	[431]	[349,195,215]	4	hSpCas9	negative selection	1531507
43054776	43054799	15	+	26627737	HeLa	viability after 15 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.5872170671244346	[109]	[3,52,32]	-5	hSpCas9	negative selection	1613817
43060092	43060115	15	-	26627737	HeLa	viability after 15 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.4250781956494505	[253]	[54,97,274]	3	hSpCas9	negative selection	1613818
43067906	43067929	15	+	26627737	HeLa	viability after 15 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.6351867680152445	[604]	[369,331,450]	5	hSpCas9	negative selection	1613819
43070898	43070921	15	-	26627737	HeLa	viability after 15 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.20023808118425568	[1099]	[416,349,402]	-2	hSpCas9	negative selection	1613820
43075067	43075090	15	-	26627737	HeLa	viability after 15 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.613770815867077	[609]	[176,106,205]	-5	hSpCas9	negative selection	1613821
43106010	43106033	15	-	26627737	HeLa	viability after 15 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.04424602962947927	[431]	[261,159,115]	0	hSpCas9	negative selection	1613822
43054776	43054799	15	+	26627737	HeLa	viability after 18 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.49544984817534643	[109]	[3,46,32]	-4	hSpCas9	negative selection	1696132
43060092	43060115	15	-	26627737	HeLa	viability after 18 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.4514378690749826	[253]	[37,85,274]	4	hSpCas9	negative selection	1696133
43067906	43067929	15	+	26627737	HeLa	viability after 18 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.6390948408401467	[604]	[250,273,450]	5	hSpCas9	negative selection	1696134
43070898	43070921	15	-	26627737	HeLa	viability after 18 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.19803377534263444	[1099]	[275,295,402]	-2	hSpCas9	negative selection	1696135
43075067	43075090	15	-	26627737	HeLa	viability after 18 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.576951824654729	[609]	[124,90,205]	-5	hSpCas9	negative selection	1696136
43106010	43106033	15	-	26627737	HeLa	viability after 18 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.06543563782166625	[431]	[182,129,115]	0	hSpCas9	negative selection	1696137
43054776	43054799	15	+	26627737	HCT116	viability after 6 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	1.345863697365973	[190]	[7,113]	7	hSpCas9	negative selection	1778447
43060092	43060115	15	-	26627737	HCT116	viability after 6 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.42430905559643023	[454]	[100,26]	-2	hSpCas9	negative selection	1778448
43067906	43067929	15	+	26627737	HCT116	viability after 6 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.7338811481857139	[1127]	[221,42]	-4	hSpCas9	negative selection	1778449
43070898	43070921	15	-	26627737	HCT116	viability after 6 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.1614114253765493	[1368]	[243,163]	-1	hSpCas9	negative selection	1778450
43075067	43075090	15	-	26627737	HCT116	viability after 6 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.5761882072944869	[783]	[208,12]	-3	hSpCas9	negative selection	1778451
43106010	43106033	15	-	26627737	HCT116	viability after 6 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-1.7811949921246994	[649]	[50,17]	-7	hSpCas9	negative selection	1778452
43054776	43054799	15	+	26627737	HCT116	viability after 8 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.5755294684224748	[104]	[55,39,20]	-6	hSpCas9	negative selection	1860762
43060092	43060115	15	-	26627737	HCT116	viability after 8 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.5591837123343488	[316]	[98,112,142]	-6	hSpCas9	negative selection	1860763
43067906	43067929	15	+	26627737	HCT116	viability after 8 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.5652642113966341	[637]	[212,233,264]	-6	hSpCas9	negative selection	1860764
43070898	43070921	15	-	26627737	HCT116	viability after 8 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.09455807940101524	[730]	[525,420,345]	1	hSpCas9	negative selection	1860765
43075067	43075090	15	-	26627737	HCT116	viability after 8 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.13203240957653212	[328]	[196,203,194]	1	hSpCas9	negative selection	1860766
43106010	43106033	15	-	26627737	HCT116	viability after 8 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.7517474148377297	[296]	[70,113,105]	-7	hSpCas9	negative selection	1860767
43054776	43054799	15	+	26627737	HCT116	viability after 9 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-1.02754342121354	[190]	[0,43]	-6	hSpCas9	negative selection	1943077
43060092	43060115	15	-	26627737	HCT116	viability after 9 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.22241981870198974	[454]	[140,74]	-1	hSpCas9	negative selection	1943078
43067906	43067929	15	+	26627737	HCT116	viability after 9 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.4143870721833258	[1127]	[654,200]	3	hSpCas9	negative selection	1943079
43070898	43070921	15	-	26627737	HCT116	viability after 9 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.19223254408866586	[1368]	[453,213]	-1	hSpCas9	negative selection	1943080
43075067	43075090	15	-	26627737	HCT116	viability after 9 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.2245253180593606	[783]	[167,187]	-1	hSpCas9	negative selection	1943081
43106010	43106033	15	-	26627737	HCT116	viability after 9 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.5428509536201405	[649]	[217,40]	-4	hSpCas9	negative selection	1943082
43054776	43054799	15	+	26627737	HCT116	viability after 12 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.16071839138729094	[104]	[39,52,55]	-2	hSpCas9	negative selection	2025392
43060092	43060115	15	-	26627737	HCT116	viability after 12 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.6683436944531824	[316]	[72,134,109]	-6	hSpCas9	negative selection	2025393
43067906	43067929	15	+	26627737	HCT116	viability after 12 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.018548692638446607	[637]	[282,362,351]	0	hSpCas9	negative selection	2025394
43070898	43070921	15	-	26627737	HCT116	viability after 12 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.22733602704733613	[730]	[394,367,588]	2	hSpCas9	negative selection	2025395
43075067	43075090	15	-	26627737	HCT116	viability after 12 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.061456081928410594	[328]	[249,173,110]	0	hSpCas9	negative selection	2025396
43106010	43106033	15	-	26627737	HCT116	viability after 12 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.42854612443324513	[296]	[139,82,121]	-4	hSpCas9	negative selection	2025397
43054776	43054799	15	+	26627737	HCT116	viability after 15 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-1.3494978066853902	[104]	[38,21,11]	-8	hSpCas9	negative selection	2107707
43060092	43060115	15	-	26627737	HCT116	viability after 15 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.8708648732184867	[316]	[153,111,39]	-7	hSpCas9	negative selection	2107708
43067906	43067929	15	+	26627737	HCT116	viability after 15 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.08876936391699342	[637]	[333,409,288]	-1	hSpCas9	negative selection	2107709
43070898	43070921	15	-	26627737	HCT116	viability after 15 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.11657350083972196	[730]	[549,374,451]	1	hSpCas9	negative selection	2107710
43075067	43075090	15	-	26627737	HCT116	viability after 15 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.07658579948011311	[328]	[100,246,179]	-1	hSpCas9	negative selection	2107711
43106010	43106033	15	-	26627737	HCT116	viability after 15 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.3382773147659673	[296]	[125,87,188]	-4	hSpCas9	negative selection	2107712
43054776	43054799	15	+	26627737	HCT116	viability after 18 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.2802280250793925	[104]	[72,64,45]	2	hSpCas9	negative selection	2190022
43060092	43060115	15	-	26627737	HCT116	viability after 18 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.39477469363128376	[316]	[118,112,117]	-4	hSpCas9	negative selection	2190023
43067906	43067929	15	+	26627737	HCT116	viability after 18 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.7448212805058441	[637]	[594,455,502]	6	hSpCas9	negative selection	2190024
43070898	43070921	15	-	26627737	HCT116	viability after 18 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.2184101456277705	[730]	[512,347,374]	2	hSpCas9	negative selection	2190025
43075067	43075090	15	-	26627737	HCT116	viability after 18 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.045822626759996	[328]	[178,145,136]	0	hSpCas9	negative selection	2190026
43106010	43106033	15	-	26627737	HCT116	viability after 18 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	-0.18652776195614065	[296]	[143,88,148]	-2	hSpCas9	negative selection	2190027
43043482	43043505	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTAGG	UBR1	ENSG00000159459	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385623
43081156	43081179	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTCAG	UBR1	ENSG00000159459	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398762
43057937	43057960	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTTGCCCAGACTAG	UBR1	ENSG00000159459	2.6118589352134576	[275,130]	[385,150]	8	dCas9-VP64	positive selection	2414688
43033929	43033952	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGTCGAGG	UBR1	ENSG00000159459	1.0128281800924883	[250,40]	[67,58]	4	dCas9-VP64	positive selection	2417041
42990420	42990443	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTTGGCCTACCAAAGTGCTGG	UBR1	ENSG00000159459	2.0515604839822705	[68,78]	[51,85]	7	dCas9-VP64	positive selection	2418592
43005641	43005664	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAATAGAAAAGGGGGAAATGTGG	UBR1	ENSG00000159459	-0.5261836086397467	[77,118]	[9,19]	-3	dCas9-VP64	positive selection	2419299
43000906	43000929	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCACCTCCCGG	UBR1	ENSG00000159459	0.058421953785092295	[801,622]	[115,212]	0	dCas9-VP64	positive selection	2420366
43091721	43091744	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTTTGAGACCAGCCTAGG	UBR1	ENSG00000159459	-1.6026008362934678	[306,558]	[26,34]	-8	dCas9-VP64	positive selection	2428518
43076279	43076302	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCTCAATGGTGCCCAGGCTGG	UBR1	ENSG00000159459	-0.5084711381371269	[26,78]	[5,9]	-2	dCas9-VP64	positive selection	2462544
43043482	43043505	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTAGG	UBR1	ENSG00000159459	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480878
43081156	43081179	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTCAG	UBR1	ENSG00000159459	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2494017
43057937	43057960	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTTGCCCAGACTAG	UBR1	ENSG00000159459	-0.18468441030242128	[164,170]	[47,47]	-2	dCas9-VP64	positive selection	2509943
43033929	43033952	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGTCGAGG	UBR1	ENSG00000159459	-0.03815698815020019	[56,33]	[21,6]	0	dCas9-VP64	positive selection	2512296
42990420	42990443	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTTGGCCTACCAAAGTGCTGG	UBR1	ENSG00000159459	-0.05988777688383007	[304,168]	[116,33]	0	dCas9-VP64	positive selection	2513847
43005641	43005664	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAATAGAAAAGGGGGAAATGTGG	UBR1	ENSG00000159459	0.026051413979125304	[91,92]	[41,19]	0	dCas9-VP64	positive selection	2514554
43000906	43000929	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCACCTCCCGG	UBR1	ENSG00000159459	0.1281772646791315	[789,694]	[166,357]	1	dCas9-VP64	positive selection	2515621
43091721	43091744	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTTTGAGACCAGCCTAGG	UBR1	ENSG00000159459	0.9241793657004961	[25,55]	[22,26]	6	dCas9-VP64	positive selection	2523773
43076279	43076302	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCTCAATGGTGCCCAGGCTGG	UBR1	ENSG00000159459	-0.1772018497958423	[109,268]	[34,71]	-2	dCas9-VP64	positive selection	2557799
43105990	43106013	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	-0.9029197107903191	[2,3]	[0,0]	-8	hSpCas9	positive selection	3030703
43036210	43036233	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	-0.36054497745491654	[3,2]	[0,2]	-5	hSpCas9	positive selection	3030704
43067930	43067953	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	0.5114333296343441	[3,3]	[3,5]	9	hSpCas9	positive selection	3030705
43105974	43105997	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.25494352293107747	[4,4]	[3,2]	-4	hSpCas9	positive selection	3030706
43105990	43106013	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	-0.13336007040213982	[2,2]	[2,0]	-2	hSpCas9	positive selection	3098561
43036210	43036233	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	-0.4049428235643707	[3,3]	[2,0]	-6	hSpCas9	positive selection	3098562
43067930	43067953	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	0.21472812360892796	[3,3]	[3,2]	4	hSpCas9	positive selection	3098563
43105974	43105997	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.4723542958680486	[4,4]	[4,0]	-6	hSpCas9	positive selection	3098564
43082649	43082672		+	24336571	A375	resistance to PLX after 7 days	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	-0.3254644334639219	[11,11]	[9,8]	-8	hSpCas9	positive selection	3154075
43074983	43075006		+	24336571	A375	resistance to PLX after 7 days	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.05667665963107932	[8,11]	[8,11]	2	hSpCas9	positive selection	3154076
43082649	43082672		+	24336571	A375	resistance to PLX after 14 days	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	-0.477156408824364	[11,14]	[3,4]	-5	hSpCas9	positive selection	3211868
43074983	43075006		+	24336571	A375	resistance to PLX after 14 days	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	-0.42770324722228936	[16,17]	[6,3]	-5	hSpCas9	positive selection	3211869
43082649	43082672		+	24336571	A375	viability after 7 days	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	0.027674819842835208	[11]	[11,11]	0	hSpCas9	negative selection	3269661
43074983	43075006		+	24336571	A375	viability after 7 days	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	-0.2992397777732718	[12]	[8,11]	-4	hSpCas9	negative selection	3269662
43082649	43082672		+	24336571	A375	viability after 14 days	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	0.19729005995118087	[11]	[11,14]	2	hSpCas9	negative selection	3327454
43074983	43075006		+	24336571	A375	viability after 14 days	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.4552549156641981	[12]	[16,17]	6	hSpCas9	negative selection	3327455
43082679	43082702	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.631417037452424	[236,236]	[0,0]	-4	hSpCas9	positive selection	3400130
43070833	43070856	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.47596649792117546	[109,109]	[0,0]	2	hSpCas9	positive selection	3400131
43074983	43075006	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	-1.96667546275227	[597,597]	[0,0]	-9	hSpCas9	positive selection	3400132
43105990	43106013	15	-	26780180	HT29	viability (Avana library 4 designs)	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	1.15050928827945	[]	[]	4	hSpCas9	negative selection	3469640
43036210	43036233	15	-	26780180	HT29	viability (Avana library 4 designs)	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	1.74485943771746	[]	[]	6	hSpCas9	negative selection	3469641
43067930	43067953	15	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	0.486568099285666	[]	[]	1	hSpCas9	negative selection	3469642
43105974	43105997	15	-	26780180	HT29	viability (Avana library 4 designs)	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.158271198490039	[]	[]	-3	hSpCas9	negative selection	3469643
43036210	43036233	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	3.8675768717317	[]	[]	6	hSpCas9	negative selection	3574969
43105974	43105997	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	4.72074907965951	[]	[]	7	hSpCas9	negative selection	3574970
43105990	43106013	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	4.95298227497352	[]	[]	8	hSpCas9	negative selection	3574971
43067930	43067953	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	2.58045553613626	[]	[]	4	hSpCas9	negative selection	3574972
43030024	43030047	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-7.64663758191843	[]	[]	-7	hSpCas9	negative selection	3574973
43086041	43086064	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGAGAAATTGAAGCACAGTGG	UBR1	ENSG00000159459	-5.80334560261712	[]	[]	-6	hSpCas9	negative selection	3574974
43036210	43036233	15	-	26780180	A375	viability (Avana lentiGuide)	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	-11.1012635572023	[]	[]	-9	hSpCas9	negative selection	3683628
43105974	43105997	15	-	26780180	A375	viability (Avana lentiGuide)	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-6.18259789220785	[]	[]	-9	hSpCas9	negative selection	3683629
43105990	43106013	15	-	26780180	A375	viability (Avana lentiGuide)	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	2.32634488360851	[]	[]	2	hSpCas9	negative selection	3683630
43067930	43067953	15	-	26780180	A375	viability (Avana lentiGuide)	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	-2.90703922161556	[]	[]	-5	hSpCas9	negative selection	3683631
43030024	43030047	15	-	26780180	A375	viability (Avana lentiGuide)	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	13.6956714665354	[]	[]	7	hSpCas9	negative selection	3683632
43086041	43086064	15	-	26780180	A375	viability (Avana lentiGuide)	TTAGAGAAATTGAAGCACAGTGG	UBR1	ENSG00000159459	-5.07555691776184	[]	[]	-8	hSpCas9	negative selection	3683633
43036210	43036233	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	-0.014222403072619523	[4]	[5,3]	0	hSpCas9	positive selection	3792235
43105974	43105997	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.24389701199864874	[6]	[6,7]	7	hSpCas9	positive selection	3792236
43105990	43106013	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	0.03782168218747842	[3]	[4,3]	0	hSpCas9	positive selection	3792237
43067930	43067953	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	0.08710830949029026	[5]	[5,5]	2	hSpCas9	positive selection	3792238
43030024	43030047	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.4731439855302303	[3]	[2,2]	-6	hSpCas9	positive selection	3792239
43086041	43086064	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGAGAAATTGAAGCACAGTGG	UBR1	ENSG00000159459	-0.6533458050338163	[6]	[4,2]	-7	hSpCas9	positive selection	3792240
43036210	43036233	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGAGGTATGAACTTGCCGAGG	UBR1	ENSG00000159459	0.02528192140973845	[4]	[3,3]	0	hSpCas9	positive selection	3900842
43105974	43105997	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.17567980214035522	[6]	[4,4]	-2	hSpCas9	positive selection	3900843
43105990	43106013	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGGCTGGAGGTACTGAGAGG	UBR1	ENSG00000159459	-1.29897676213644	[5]	[1,0]	-9	hSpCas9	positive selection	3900844
43067930	43067953	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGACTGTGAGCTCGCAGAGG	UBR1	ENSG00000159459	0.30507999483822473	[5]	[5,6]	8	hSpCas9	positive selection	3900845
43030024	43030047	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.37038386560277853	[5]	[1,4]	-5	hSpCas9	positive selection	3900846
43086041	43086064	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGAGAAATTGAAGCACAGTGG	UBR1	ENSG00000159459	0.19347827640477125	[5]	[4,6]	5	hSpCas9	positive selection	3900847
43070898	43070921	15	-	26780180	A375	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.733981623008306	[]	[]	2	hSpCas9	negative selection	4009948
43070833	43070856	15	-	26780180	A375	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.929109632569848	[]	[]	4	hSpCas9	negative selection	4009949
43075073	43075096	15	-	26780180	A375	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	1.09608481795479	[]	[]	5	hSpCas9	negative selection	4009950
43082637	43082660	15	-	26780180	A375	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.0346753485598895	[]	[]	0	hSpCas9	negative selection	4009951
43082679	43082702	15	-	26780180	A375	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.617183457943607	[]	[]	2	hSpCas9	negative selection	4009952
43074983	43075006	15	+	26780180	A375	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.703522961852647	[]	[]	2	hSpCas9	negative selection	4009953
43070898	43070921	15	-	26780180	HT29	viability (GeCKOv2 library)	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.0596112969853113	[]	[]	0	hSpCas9	negative selection	4117914
43070833	43070856	15	-	26780180	HT29	viability (GeCKOv2 library)	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	1.49752058170555	[]	[]	7	hSpCas9	negative selection	4117915
43075073	43075096	15	-	26780180	HT29	viability (GeCKOv2 library)	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.860812904578139	[]	[]	3	hSpCas9	negative selection	4117916
43082637	43082660	15	-	26780180	HT29	viability (GeCKOv2 library)	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.465050035950466	[]	[]	1	hSpCas9	negative selection	4117917
43082679	43082702	15	-	26780180	HT29	viability (GeCKOv2 library)	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.937655405529246	[]	[]	4	hSpCas9	negative selection	4117918
43074983	43075006	15	+	26780180	HT29	viability (GeCKOv2 library)	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	1.29315034728974	[]	[]	6	hSpCas9	negative selection	4117919
43082649	43082672	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	-0.004741618398442171	[3]	[1,1]	0	hSpCas9	positive selection	4180748
43074983	43075006	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.12272502458484028	[2]	[1,2]	3	hSpCas9	positive selection	4180749
43082649	43082672	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATTTTTATGAACACTGTCCTGG	UBR1	ENSG00000159459	-0.33210453612631874	[3]	[0,2,1,0]	-5	hSpCas9	positive selection	4244770
43074983	43075006	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.7560919455370818	[3]	[1,0,0,4]	5	hSpCas9	positive selection	4244771
43070898	43070921	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.13620017248522953	[1]	[0,1]	2	hSpCas9	positive selection	4306365
43075073	43075096	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.1681183210824271	[2]	[2,0]	-3	hSpCas9	positive selection	4306366
43082637	43082660	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.37695237960151756	[3]	[4,2]	7	hSpCas9	positive selection	4306367
43082679	43082702	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.018672127419262934	[3]	[3,1]	0	hSpCas9	positive selection	4370614
43070833	43070856	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.012311377458746248	[2]	[2,1]	0	hSpCas9	positive selection	4370615
43074983	43075006	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.07221455708162633	[4]	[3,3]	1	hSpCas9	positive selection	4370616
43030050	43030072	15	-	27760321	OCIAML3	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.2424369980342087	[263,239]	[74,93]	-8	hSpCas9	negative selection	4451971
43037829	43037851	15	+	27760321	OCIAML3	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	1.4836435060273567	[105,77]	[181,221]	9	hSpCas9	negative selection	4451972
43038205	43038227	15	-	27760321	OCIAML3	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	0.7277367465978716	[423,372]	[472,569]	8	hSpCas9	negative selection	4451973
43060092	43060114	15	-	27760321	OCIAML3	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.13700783650429527	[502,433]	[241,449]	-1	hSpCas9	negative selection	4451974
43070898	43070920	15	-	27760321	OCIAML3	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.27142258248211876	[620,458]	[403,636]	3	hSpCas9	negative selection	4451975
43030050	43030072	15	-	27760321	OCIAML2	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-0.09642072382220845	[263,239]	[108,297]	-1	hSpCas9	negative selection	4535434
43037829	43037851	15	+	27760321	OCIAML2	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	1.4511796346685348	[105,77]	[151,266]	9	hSpCas9	negative selection	4535435
43038205	43038227	15	-	27760321	OCIAML2	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.1113734457288427	[423,372]	[217,402]	-1	hSpCas9	negative selection	4535436
43060092	43060114	15	-	27760321	OCIAML2	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.29847113287914695	[502,433]	[365,594]	4	hSpCas9	negative selection	4535437
43070898	43070920	15	-	27760321	OCIAML2	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.18032149103278505	[620,458]	[293,497]	-2	hSpCas9	negative selection	4535438
43030050	43030072	15	-	27760321	MV411	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-0.5731092282449158	[263,239]	[0,277]	-4	hSpCas9	negative selection	4618897
43037829	43037851	15	+	27760321	MV411	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.42517054151496914	[105,77]	[41,138]	3	hSpCas9	negative selection	4618898
43038205	43038227	15	-	27760321	MV411	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-1.8664545673443271	[423,372]	[43,113]	-8	hSpCas9	negative selection	4618899
43060092	43060114	15	-	27760321	MV411	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.24976738124142772	[502,433]	[348,392]	1	hSpCas9	negative selection	4618900
43070898	43070920	15	-	27760321	MV411	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.889753422811087	[620,458]	[531,837]	6	hSpCas9	negative selection	4618901
43030050	43030072	15	-	27760321	HL60	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-0.7278442383759497	[263,239]	[147,98]	-6	hSpCas9	negative selection	4702360
43037829	43037851	15	+	27760321	HL60	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	1.2674629529110155	[105,77]	[137,222]	9	hSpCas9	negative selection	4702361
43038205	43038227	15	-	27760321	HL60	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.8367196583744917	[423,372]	[211,149]	-7	hSpCas9	negative selection	4702362
43060092	43060114	15	-	27760321	HL60	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.21570657763290874	[502,433]	[316,340]	-2	hSpCas9	negative selection	4702363
43070898	43070920	15	-	27760321	HL60	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.849095388582783	[620,458]	[834,736]	8	hSpCas9	negative selection	4702364
43030050	43030072	15	-	27760321	HT1080	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	0.6751537327425702	[239,186]	[141,128]	3	hSpCas9	negative selection	4785823
43037829	43037851	15	+	27760321	HT1080	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	2.255523799813705	[77,60]	[157,103]	9	hSpCas9	negative selection	4785824
43038205	43038227	15	-	27760321	HT1080	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	1.846806066820271	[372,290]	[606,331]	8	hSpCas9	negative selection	4785825
43060092	43060114	15	-	27760321	HT1080	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.020688925388699583	[433,338]	[170,139]	0	hSpCas9	negative selection	4785826
43070898	43070920	15	-	27760321	HT1080	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	1.5427229852236422	[458,357]	[296,667]	8	hSpCas9	negative selection	4785827
43030050	43030072	15	-	27760321	HT29	viability after 7 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.4695987456673092	[239,186]	[206,83,23]	-9	hSpCas9	negative selection	4869286
43037829	43037851	15	+	27760321	HT29	viability after 7 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.551452261126723	[77,60]	[138,95,157]	8	hSpCas9	negative selection	4869287
43038205	43038227	15	-	27760321	HT29	viability after 7 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.40093444529795913	[372,290]	[331,422,218]	-5	hSpCas9	negative selection	4869288
43060092	43060114	15	-	27760321	HT29	viability after 7 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.07810716894318617	[433,338]	[587,549,295]	-1	hSpCas9	negative selection	4869289
43070898	43070920	15	-	27760321	HT29	viability after 7 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.18192313196974103	[458,357]	[666,545,583]	2	hSpCas9	negative selection	4869290
43030050	43030072	15	-	27760321	HT29	viability after 25 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.6785824986902877	[239,186]	[104,42,78]	-7	hSpCas9	negative selection	4952749
43037829	43037851	15	+	27760321	HT29	viability after 25 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.44123858209796185	[77,60]	[96,119,106]	5	hSpCas9	negative selection	4952750
43038205	43038227	15	-	27760321	HT29	viability after 25 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.22059078135626764	[372,290]	[470,266,217]	-2	hSpCas9	negative selection	4952751
43060092	43060114	15	-	27760321	HT29	viability after 25 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.14616383772864477	[433,338]	[500,302,384]	-1	hSpCas9	negative selection	4952752
43070898	43070920	15	-	27760321	HT29	viability after 25 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.23314194876902966	[458,357]	[428,707,511]	2	hSpCas9	negative selection	4952753
43030050	43030072	15	-	27760321	HT29	viability after 22 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.2595287420546923	[239,186]	[230,52,20]	-7	hSpCas9	negative selection	5036212
43037829	43037851	15	+	27760321	HT29	viability after 22 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.8062589549096324	[77,60]	[92,170,158]	8	hSpCas9	negative selection	5036213
43038205	43038227	15	-	27760321	HT29	viability after 22 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.1835402282458472	[372,290]	[352,262,397]	-2	hSpCas9	negative selection	5036214
43060092	43060114	15	-	27760321	HT29	viability after 22 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.24010857459649643	[433,338]	[742,453,378]	2	hSpCas9	negative selection	5036215
43070898	43070920	15	-	27760321	HT29	viability after 22 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.07746181775945582	[458,357]	[322,734,440]	0	hSpCas9	negative selection	5036216
43030050	43030072	15	-	27760321	HT29	viability after 19 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.328035850874072	[239,186]	[76,19,188]	-7	hSpCas9	negative selection	5119675
43037829	43037851	15	+	27760321	HT29	viability after 19 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.23570968063424358	[77,60]	[182,90,18]	2	hSpCas9	negative selection	5119676
43038205	43038227	15	-	27760321	HT29	viability after 19 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.3176848429542546	[372,290]	[322,323,269]	-3	hSpCas9	negative selection	5119677
43060092	43060114	15	-	27760321	HT29	viability after 19 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.31032720436058825	[433,338]	[302,863,454]	3	hSpCas9	negative selection	5119678
43070898	43070920	15	-	27760321	HT29	viability after 19 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.10904534221582607	[458,357]	[656,466,406]	1	hSpCas9	negative selection	5119679
43030050	43030072	15	-	27760321	HT29	viability after 16 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.2694840557066902	[239,186]	[127,19,153]	-7	hSpCas9	negative selection	5203138
43037829	43037851	15	+	27760321	HT29	viability after 16 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.1499100361668173	[77,60]	[82,67,107]	1	hSpCas9	negative selection	5203139
43038205	43038227	15	-	27760321	HT29	viability after 16 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.3681391844465295	[372,290]	[432,249,194]	-4	hSpCas9	negative selection	5203140
43060092	43060114	15	-	27760321	HT29	viability after 16 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.11076127922491728	[433,338]	[297,382,705]	1	hSpCas9	negative selection	5203141
43070898	43070920	15	-	27760321	HT29	viability after 16 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.30797218662687753	[458,357]	[489,720,474]	3	hSpCas9	negative selection	5203142
43030050	43030072	15	-	27760321	HT29	viability after 13 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-0.7228866720556343	[239,186]	[153,109,183]	-6	hSpCas9	negative selection	5286601
43037829	43037851	15	+	27760321	HT29	viability after 13 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.41157567150522834	[77,60]	[140,112,69]	5	hSpCas9	negative selection	5286602
43038205	43038227	15	-	27760321	HT29	viability after 13 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.3466085771439608	[372,290]	[314,399,199]	-4	hSpCas9	negative selection	5286603
43060092	43060114	15	-	27760321	HT29	viability after 13 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.15781034048957954	[433,338]	[450,392,363]	-2	hSpCas9	negative selection	5286604
43070898	43070920	15	-	27760321	HT29	viability after 13 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.3560178686230411	[458,357]	[725,517,576]	4	hSpCas9	negative selection	5286605
43030050	43030072	15	-	27760321	HT29	viability after 10 days	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-1.9047830081711519	[239,186]	[67,81,63]	-9	hSpCas9	negative selection	5370064
43037829	43037851	15	+	27760321	HT29	viability after 10 days	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.32569830723862925	[77,60]	[182,89,53]	4	hSpCas9	negative selection	5370065
43038205	43038227	15	-	27760321	HT29	viability after 10 days	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.5289227730932586	[372,290]	[336,328,198]	-6	hSpCas9	negative selection	5370066
43060092	43060114	15	-	27760321	HT29	viability after 10 days	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.05287632683252447	[433,338]	[503,455,435]	0	hSpCas9	negative selection	5370067
43070898	43070920	15	-	27760321	HT29	viability after 10 days	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.3477579897139479	[458,357]	[447,718,778]	5	hSpCas9	negative selection	5370068
43030050	43030072	15	-	27760321	MOLM13	viability	TAGGTGAGCGTTATGTACCTGG	UBR1	ENSG00000159459	-0.13504296608221233	[263,239]	[224,47]	-1	hSpCas9	negative selection	5453527
43037829	43037851	15	+	27760321	MOLM13	viability	CCAACACCAGACAACGTAAAGG	UBR1	ENSG00000159459	0.6097701846388015	[105,77]	[145,20]	4	hSpCas9	negative selection	5453528
43038205	43038227	15	-	27760321	MOLM13	viability	ATGTACGTTTAAGCAGGCTGGG	UBR1	ENSG00000159459	-0.28110917717252426	[423,372]	[242,134]	-2	hSpCas9	negative selection	5453529
43060092	43060114	15	-	27760321	MOLM13	viability	GTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.6605337653733372	[502,433]	[427,406]	4	hSpCas9	negative selection	5453530
43070898	43070920	15	-	27760321	MOLM13	viability	CGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.959966786046923	[620,458]	[979,252]	6	hSpCas9	negative selection	5453531
43105886	43105909	15	+	27661255	K562	viability	GCGCAGTAGGGAGGGACCGGGGG	UBR1	ENSG00000159459	-0.36426624183984924	[345,419]	[292,188]	-7	dCas9-KRAB	negative selection	5521257
43105524	43105547	15	-	27661255	K562	viability	GGCCGGGACCTGATATTGGTAGG	UBR1	ENSG00000159459	-0.02473237071378731	[445,459]	[395,320]	-1	dCas9-KRAB	negative selection	5521258
43105986	43106009	15	-	27661255	K562	viability	GGCTGGAGGTACTGAGAGGATGG	UBR1	ENSG00000159459	-0.3603073749285808	[692,721]	[440,438]	-7	dCas9-KRAB	negative selection	5521259
43070898	43070921	15	-	27260156	BXPC3	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5483105106175334	[125]	[201,220,147,194]	9	hSpCas9	negative selection	5578825
43075073	43075096	15	-	27260156	BXPC3	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.05220548681112008	[371]	[350,416,344,514]	1	hSpCas9	negative selection	5578826
43082637	43082660	15	-	27260156	BXPC3	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.1463581531400452	[635]	[627,708,780,848]	3	hSpCas9	negative selection	5578827
43082679	43082702	15	-	27260156	BXPC3	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.1494170025759221	[523]	[579,607,516,738]	3	hSpCas9	negative selection	5643074
43070833	43070856	15	-	27260156	BXPC3	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.17219953497245438	[378]	[366,287,385,367]	-4	hSpCas9	negative selection	5643075
43074983	43075006	15	+	27260156	BXPC3	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.13789604633718344	[1390]	[1473,1535,1733,1674]	3	hSpCas9	negative selection	5643076
43070898	43070921	15	-	27260156	A673	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.18719467176211624	[125]	[194,153,181,159]	4	hSpCas9	negative selection	5700076
43075073	43075096	15	-	27260156	A673	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.3230708434651346	[371]	[341,354,439,283]	-7	hSpCas9	negative selection	5700077
43082637	43082660	15	-	27260156	A673	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.08637352351869432	[635]	[880,762,722,888]	2	hSpCas9	negative selection	5700078
43082679	43082702	15	-	27260156	A673	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.01843707234492714	[523]	[610,608,589,675]	0	hSpCas9	negative selection	5764325
43070833	43070856	15	-	27260156	A673	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.31069086968005	[378]	[402,304,417,344]	-6	hSpCas9	negative selection	5764326
43074983	43075006	15	+	27260156	A673	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.12388644972482576	[1390]	[2054,1669,1628,1962]	3	hSpCas9	negative selection	5764327
43070898	43070921	15	-	27260156	A375	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.3946698369247992	[125]	[221,157,144,237]	6	hSpCas9	negative selection	5821327
43075073	43075096	15	-	27260156	A375	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.17127865392925856	[371]	[386,541,279,357]	-2	hSpCas9	negative selection	5821328
43082637	43082660	15	-	27260156	A375	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.566066154629716	[635]	[1145,1199,1193,893]	8	hSpCas9	negative selection	5821329
43082679	43082702	15	-	27260156	A375	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.5295308259116205	[523]	[892,757,969,890]	7	hSpCas9	negative selection	5885576
43070833	43070856	15	-	27260156	A375	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.08883886824473788	[378]	[419,480,608,382]	1	hSpCas9	negative selection	5885577
43074983	43075006	15	+	27260156	A375	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.3046558406219706	[1390]	[1931,2419,1940,1806]	4	hSpCas9	negative selection	5885578
43070898	43070921	15	-	27260156	COLO741	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.6111099140968284	[125]	[318,272,157]	9	hSpCas9	negative selection	5942578
43075073	43075096	15	-	27260156	COLO741	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.14554171616462352	[371]	[598,410,301]	-3	hSpCas9	negative selection	5942579
43082637	43082660	15	-	27260156	COLO741	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.02713506577232566	[635]	[937,719,832]	0	hSpCas9	negative selection	5942580
43082679	43082702	15	-	27260156	COLO741	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.02966257182065138	[523]	[599,676,758]	0	hSpCas9	negative selection	6006827
43070833	43070856	15	-	27260156	COLO741	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.12213676807280044	[378]	[528,355,454]	-3	hSpCas9	negative selection	6006828
43074983	43075006	15	+	27260156	COLO741	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.1693851106008124	[1390]	[2125,1958,1922]	3	hSpCas9	negative selection	6006829
43070898	43070921	15	-	27260156	CAL120	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.46730976788149303	[125]	[94,49,190]	-6	hSpCas9	negative selection	6063829
43075073	43075096	15	-	27260156	CAL120	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.5456050206512247	[371]	[380,323,256]	-7	hSpCas9	negative selection	6063830
43082637	43082660	15	-	27260156	CAL120	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.22975115872788665	[635]	[849,823,1094]	3	hSpCas9	negative selection	6063831
43082679	43082702	15	-	27260156	CAL120	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.4532229964965559	[523]	[833,998,836]	6	hSpCas9	negative selection	6128078
43070833	43070856	15	-	27260156	CAL120	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.07128717323588998	[378]	[412,625,435]	1	hSpCas9	negative selection	6128079
43074983	43075006	15	+	27260156	CAL120	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.16555702193728106	[1390]	[1939,1871,2009]	2	hSpCas9	negative selection	6128080
43070898	43070921	15	-	27260156	CADOES1	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.2147242736631949	[125]	[177,131,119,112]	3	hSpCas9	negative selection	6185080
43075073	43075096	15	-	27260156	CADOES1	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.1838631027200237	[371]	[349,267,400,194]	-3	hSpCas9	negative selection	6185081
43082637	43082660	15	-	27260156	CADOES1	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.4896986483298241	[635]	[1069,504,711,1041]	7	hSpCas9	negative selection	6185082
43082679	43082702	15	-	27260156	CADOES1	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.4087117959130962	[523]	[556,587,767,675]	6	hSpCas9	negative selection	6249329
43070833	43070856	15	-	27260156	CADOES1	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.2995584929674455	[378]	[271,395,264,209]	-5	hSpCas9	negative selection	6249330
43074983	43075006	15	+	27260156	CADOES1	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.24260009841544639	[1390]	[1563,1663,1432,1458]	4	hSpCas9	negative selection	6249331
43070898	43070921	15	-	27260156	EWS502	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5386553374489347	[125]	[200,131,155,293]	8	hSpCas9	negative selection	6306331
43075073	43075096	15	-	27260156	EWS502	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.5811079001406242	[371]	[303,224,208,313]	-7	hSpCas9	negative selection	6306332
43082637	43082660	15	-	27260156	EWS502	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.4139556386167468	[635]	[811,1053,850,870]	7	hSpCas9	negative selection	6306333
43082679	43082702	15	-	27260156	EWS502	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.21017175360283308	[523]	[527,725,658,664]	3	hSpCas9	negative selection	6370580
43070833	43070856	15	-	27260156	EWS502	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.7700394673706691	[378]	[168,290,165,325]	-8	hSpCas9	negative selection	6370581
43074983	43075006	15	+	27260156	EWS502	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.2805907412896853	[1390]	[1771,1620,1710,2075]	5	hSpCas9	negative selection	6370582
43070898	43070921	15	-	27260156	EW8	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.6531616154026387	[125]	[243,197,85,135]	9	hSpCas9	negative selection	6427582
43075073	43075096	15	-	27260156	EW8	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.24201829296196642	[371]	[168,271,250,317]	-4	hSpCas9	negative selection	6427583
43082637	43082660	15	-	27260156	EW8	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.2504319454550853	[635]	[657,701,513,598]	4	hSpCas9	negative selection	6427584
43082679	43082702	15	-	27260156	EW8	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.03497239984750425	[523]	[429,437,377,501]	0	hSpCas9	negative selection	6491831
43070833	43070856	15	-	27260156	EW8	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.017145364275712227	[378]	[352,299,289,277]	0	hSpCas9	negative selection	6491832
43074983	43075006	15	+	27260156	EW8	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.1909049858991838	[1390]	[1296,1356,1310,1175]	3	hSpCas9	negative selection	6491833
43070898	43070921	15	-	27260156	CORL105	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.13834705874535502	[125]	[126,175,144,196]	2	hSpCas9	negative selection	6548833
43075073	43075096	15	-	27260156	CORL105	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.5727574559098946	[371]	[289,248,319,316]	-8	hSpCas9	negative selection	6548834
43082637	43082660	15	-	27260156	CORL105	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.18965884453975745	[635]	[703,856,888,946]	3	hSpCas9	negative selection	6548835
43082679	43082702	15	-	27260156	CORL105	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.25167327569179043	[523]	[719,603,925,703]	5	hSpCas9	negative selection	6613082
43070833	43070856	15	-	27260156	CORL105	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.7549043400228236	[378]	[243,182,355,283]	-8	hSpCas9	negative selection	6613083
43074983	43075006	15	+	27260156	CORL105	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.039094348642983556	[1390]	[1637,1575,2115,1432]	0	hSpCas9	negative selection	6613084
43070898	43070921	15	-	27260156	HS294T	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.34527843405949854	[125]	[75,27,61,84]	4	hSpCas9	negative selection	6670084
43075073	43075096	15	-	27260156	HS294T	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.25364084508598017	[371]	[111,59,97,233]	-4	hSpCas9	negative selection	6670085
43082637	43082660	15	-	27260156	HS294T	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.06738146049588534	[635]	[225,231,351,216]	0	hSpCas9	negative selection	6670086
43082679	43082702	15	-	27260156	HS294T	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.2977811402319599	[523]	[227,207,332,225]	4	hSpCas9	negative selection	6734333
43070833	43070856	15	-	27260156	HS294T	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.07000769623668912	[378]	[62,186,122,200]	-1	hSpCas9	negative selection	6734334
43074983	43075006	15	+	27260156	HS294T	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.38442671070380197	[1390]	[514,810,633,891]	5	hSpCas9	negative selection	6734335
43070898	43070921	15	-	27260156	HCC44	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.427563515189298	[125]	[137,317,104,166]	7	hSpCas9	negative selection	6791335
43075073	43075096	15	-	27260156	HCC44	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.2219582226193093	[371]	[530,409,714,360]	3	hSpCas9	negative selection	6791336
43082637	43082660	15	-	27260156	HCC44	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.10867214313903639	[635]	[930,617,867,732]	1	hSpCas9	negative selection	6791337
43082679	43082702	15	-	27260156	HCC44	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.2752004421442432	[523]	[835,492,1092,553]	4	hSpCas9	negative selection	6855584
43070833	43070856	15	-	27260156	HCC44	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.12865464476178196	[378]	[603,224,424,360]	-2	hSpCas9	negative selection	6855585
43074983	43075006	15	+	27260156	HCC44	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.15727391265825785	[1390]	[1497,1695,2216,1659]	2	hSpCas9	negative selection	6855586
43070898	43070921	15	-	27260156	G402	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.4138093815003585	[125]	[168,230,255,160]	5	hSpCas9	negative selection	6912586
43075073	43075096	15	-	27260156	G402	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.6372692473402282	[371]	[282,183,406,284]	-7	hSpCas9	negative selection	6912587
43082637	43082660	15	-	27260156	G402	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.41808732078120014	[635]	[1598,944,797,884]	5	hSpCas9	negative selection	6912588
43082679	43082702	15	-	27260156	G402	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.019819563396000384	[523]	[677,362,744,720]	0	hSpCas9	negative selection	6976835
43070833	43070856	15	-	27260156	G402	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.025808531170301408	[378]	[649,480,469,253]	0	hSpCas9	negative selection	6976836
43074983	43075006	15	+	27260156	G402	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.3194620744358698	[1390]	[3183,1798,1981,1656]	4	hSpCas9	negative selection	6976837
43070898	43070921	15	-	27260156	L33	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.3719647250119851	[125]	[95,33,57,117]	-7	hSpCas9	negative selection	7033837
43075073	43075096	15	-	27260156	L33	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.2417595142810558	[371]	[311,137,209,275]	-5	hSpCas9	negative selection	7033838
43082637	43082660	15	-	27260156	L33	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	-0.09185817597564366	[635]	[576,267,325,636]	-2	hSpCas9	negative selection	7033839
43082679	43082702	15	-	27260156	L33	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.05201442935697484	[523]	[486,208,359,603]	1	hSpCas9	negative selection	7098086
43070833	43070856	15	-	27260156	L33	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.2399804033028019	[378]	[330,117,264,243]	-5	hSpCas9	negative selection	7098087
43074983	43075006	15	+	27260156	L33	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.07477528271665479	[1390]	[1312,605,934,1582]	1	hSpCas9	negative selection	7098088
43070898	43070921	15	-	27260156	K562	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.055863669680575656	[125]	[209,78,138,49]	0	hSpCas9	negative selection	7155088
43075073	43075096	15	-	27260156	K562	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.49148008998441306	[371]	[643,386,660,203]	6	hSpCas9	negative selection	7155089
43082637	43082660	15	-	27260156	K562	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.2582727797011247	[635]	[821,507,906,485]	3	hSpCas9	negative selection	7155090
43082679	43082702	15	-	27260156	K562	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.2702143927230784	[523]	[943,527,440,378]	3	hSpCas9	negative selection	7219337
43070833	43070856	15	-	27260156	K562	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.28227644889772574	[378]	[186,310,215,373]	-3	hSpCas9	negative selection	7219338
43074983	43075006	15	+	27260156	K562	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.43895994551025663	[1390]	[2111,1820,1716,1142]	5	hSpCas9	negative selection	7219339
43070898	43070921	15	-	27260156	HT29	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5471667166233938	[125]	[201,298,223,178]	9	hSpCas9	negative selection	7276339
43075073	43075096	15	-	27260156	HT29	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.1590896799492515	[371]	[315,463,463,374]	-3	hSpCas9	negative selection	7276340
43082637	43082660	15	-	27260156	HT29	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.1838380166485778	[635]	[876,934,980,735]	3	hSpCas9	negative selection	7276341
43082679	43082702	15	-	27260156	HT29	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.0037312823442232634	[523]	[692,700,689,481]	0	hSpCas9	negative selection	7340588
43070833	43070856	15	-	27260156	HT29	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.3239189874853198	[378]	[318,347,508,296]	-6	hSpCas9	negative selection	7340589
43074983	43075006	15	+	27260156	HT29	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.23478840065081963	[1390]	[2226,2337,1620,1826]	4	hSpCas9	negative selection	7340590
43070898	43070921	15	-	27260156	MHHES1	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.6787184039734062	[125]	[267,255,251,152]	9	hSpCas9	negative selection	7397590
43075073	43075096	15	-	27260156	MHHES1	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.09706590413167182	[371]	[473,414,276,400]	-2	hSpCas9	negative selection	7397591
43082637	43082660	15	-	27260156	MHHES1	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.36836101604967086	[635]	[913,926,834,984]	6	hSpCas9	negative selection	7397592
43082679	43082702	15	-	27260156	MHHES1	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.31359894119541115	[523]	[804,714,800,627]	6	hSpCas9	negative selection	7461839
43070833	43070856	15	-	27260156	MHHES1	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.6229983123126482	[378]	[427,311,313,109]	-8	hSpCas9	negative selection	7461840
43074983	43075006	15	+	27260156	MHHES1	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.3344016975895152	[1390]	[1991,2368,1890,1707]	6	hSpCas9	negative selection	7461841
43070898	43070921	15	-	27260156	MEWO	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.4118809390374525	[125]	[256,128,103]	8	hSpCas9	negative selection	7518841
43075073	43075096	15	-	27260156	MEWO	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.29898518997444934	[371]	[284,283,279]	-6	hSpCas9	negative selection	7518842
43082637	43082660	15	-	27260156	MEWO	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.18269009583638607	[635]	[643,635,739]	4	hSpCas9	negative selection	7518843
43082679	43082702	15	-	27260156	MEWO	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.047240316598050086	[523]	[559,485,483]	1	hSpCas9	negative selection	7583090
43070833	43070856	15	-	27260156	MEWO	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.36193715537452775	[378]	[349,276,214]	-7	hSpCas9	negative selection	7583091
43074983	43075006	15	+	27260156	MEWO	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.027314835786955705	[1390]	[1582,1155,1289]	0	hSpCas9	negative selection	7583092
43070898	43070921	15	-	27260156	LNCAPCLONEFGC	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.24480192650871935	[125]	[152,118,184,91]	4	hSpCas9	negative selection	7640092
43075073	43075096	15	-	27260156	LNCAPCLONEFGC	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.25995217377977864	[371]	[275,299,332,222]	-4	hSpCas9	negative selection	7640093
43082637	43082660	15	-	27260156	LNCAPCLONEFGC	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.3381142344874839	[635]	[640,810,762,698]	5	hSpCas9	negative selection	7640094
43082679	43082702	15	-	27260156	LNCAPCLONEFGC	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.3562123491592259	[523]	[518,534,630,754]	5	hSpCas9	negative selection	7704341
43070833	43070856	15	-	27260156	LNCAPCLONEFGC	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.02367101605849653	[378]	[364,282,446,274]	0	hSpCas9	negative selection	7704342
43074983	43075006	15	+	27260156	LNCAPCLONEFGC	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.31469170243878275	[1390]	[1316,1328,1861,1823]	5	hSpCas9	negative selection	7704343
43070898	43070921	15	-	27260156	PANC0327	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	1.2629203339049955	[125]	[330,155,294,311]	9	hSpCas9	negative selection	7761343
43075073	43075096	15	-	27260156	PANC0327	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.47155114150567634	[371]	[398,247,559,647]	7	hSpCas9	negative selection	7761344
43082637	43082660	15	-	27260156	PANC0327	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.6266384669988029	[635]	[1252,594,910,796]	8	hSpCas9	negative selection	7761345
43082679	43082702	15	-	27260156	PANC0327	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.36979644778925164	[523]	[570,657,630,535]	5	hSpCas9	negative selection	7825592
43070833	43070856	15	-	27260156	PANC0327	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.02044787863195907	[378]	[485,339,198,313]	0	hSpCas9	negative selection	7825593
43074983	43075006	15	+	27260156	PANC0327	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.26894003023458124	[1390]	[1562,1630,1566,1181]	4	hSpCas9	negative selection	7825594
43070898	43070921	15	-	27260156	NCIH2009	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.0156628671435457	[125]	[183,220,128]	0	hSpCas9	negative selection	7882594
43075073	43075096	15	-	27260156	NCIH2009	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.3535036167775588	[371]	[551,317,379]	-5	hSpCas9	negative selection	7882595
43082637	43082660	15	-	27260156	NCIH2009	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.18081471961440398	[635]	[1091,883,1062]	2	hSpCas9	negative selection	7882596
43082679	43082702	15	-	27260156	NCIH2009	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.4280771278797442	[523]	[1002,869,1085]	6	hSpCas9	negative selection	7946843
43070833	43070856	15	-	27260156	NCIH2009	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.16082172472298767	[378]	[380,521,497]	-2	hSpCas9	negative selection	7946844
43074983	43075006	15	+	27260156	NCIH2009	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.26988402136178524	[1390]	[2891,1967,2280]	3	hSpCas9	negative selection	7946845
43070898	43070921	15	-	27260156	NCIH1373	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-1.1466910285986132	[125]	[113,85,31,6]	-8	hSpCas9	negative selection	8003845
43075073	43075096	15	-	27260156	NCIH1373	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.400316580668044	[371]	[338,230,236,125]	-4	hSpCas9	negative selection	8003846
43082637	43082660	15	-	27260156	NCIH1373	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.8716886335677437	[635]	[1023,738,780,731]	8	hSpCas9	negative selection	8003847
43082679	43082702	15	-	27260156	NCIH1373	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.7498441655312551	[523]	[1363,662,703,350]	7	hSpCas9	negative selection	8068094
43070833	43070856	15	-	27260156	NCIH1373	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.4058974149767073	[378]	[215,272,569,51]	-4	hSpCas9	negative selection	8068095
43074983	43075006	15	+	27260156	NCIH1373	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.5315791387870605	[1390]	[2792,1849,1664,754]	5	hSpCas9	negative selection	8068096
43070898	43070921	15	-	27260156	PATU8902	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5037935845928572	[125]	[278,115,227,391]	5	hSpCas9	negative selection	8125096
43075073	43075096	15	-	27260156	PATU8902	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.22583176310632708	[371]	[763,770,559,296]	2	hSpCas9	negative selection	8125097
43082637	43082660	15	-	27260156	PATU8902	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.7119049951196649	[635]	[1064,1954,1268,1570]	7	hSpCas9	negative selection	8125098
43082679	43082702	15	-	27260156	PATU8902	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	1.380276796438594	[523]	[1713,1060,2401,2326]	9	hSpCas9	negative selection	8189345
43070833	43070856	15	-	27260156	PATU8902	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.7444562543851685	[378]	[1037,643,820,1061]	7	hSpCas9	negative selection	8189346
43074983	43075006	15	+	27260156	PATU8902	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.6720395485021615	[1390]	[3354,2648,2888,3527]	7	hSpCas9	negative selection	8189347
43070898	43070921	15	-	27260156	PANC1	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.6848142700923086	[125]	[272,189,101,134]	9	hSpCas9	negative selection	8246347
43075073	43075096	15	-	27260156	PANC1	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	0.15222108049224153	[371]	[269,379,503,280]	2	hSpCas9	negative selection	8246348
43082637	43082660	15	-	27260156	PANC1	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.18543631715489206	[635]	[676,840,474,537]	3	hSpCas9	negative selection	8246349
43082679	43082702	15	-	27260156	PANC1	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.5520020750510746	[523]	[776,699,610,561]	8	hSpCas9	negative selection	8310596
43070833	43070856	15	-	27260156	PANC1	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.015936526166896392	[378]	[205,498,277,359]	0	hSpCas9	negative selection	8310597
43074983	43075006	15	+	27260156	PANC1	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.3625367797961814	[1390]	[1244,2104,1326,1558]	6	hSpCas9	negative selection	8310598
43070898	43070921	15	-	27260156	PANC0813	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.15718004617399206	[125]	[114,130,215,191]	2	hSpCas9	negative selection	8367598
43075073	43075096	15	-	27260156	PANC0813	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.12796787395451636	[371]	[467,312,298,517]	-2	hSpCas9	negative selection	8367599
43082637	43082660	15	-	27260156	PANC0813	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.3667354994922003	[635]	[807,894,1149,983]	6	hSpCas9	negative selection	8367600
43082679	43082702	15	-	27260156	PANC0813	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.1278850825262799	[523]	[729,846,576,546]	2	hSpCas9	negative selection	8431847
43070833	43070856	15	-	27260156	PANC0813	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.4883697020367346	[378]	[517,335,210,226]	-6	hSpCas9	negative selection	8431848
43074983	43075006	15	+	27260156	PANC0813	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.048624349103357334	[1390]	[1517,1994,1689,1545]	0	hSpCas9	negative selection	8431849
43070898	43070921	15	-	27260156	RDES	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.19017370329649208	[125]	[91,72,180,181]	-3	hSpCas9	negative selection	8488849
43075073	43075096	15	-	27260156	RDES	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.060008359462561	[371]	[338,407,375,539]	-1	hSpCas9	negative selection	8488850
43082637	43082660	15	-	27260156	RDES	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.36001805788084074	[635]	[758,867,1031,1148]	6	hSpCas9	negative selection	8488851
43082679	43082702	15	-	27260156	RDES	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.28284385243193394	[523]	[566,812,658,925]	4	hSpCas9	negative selection	8553098
43070833	43070856	15	-	27260156	RDES	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	0.005775727455608337	[378]	[351,501,403,498]	0	hSpCas9	negative selection	8553099
43074983	43075006	15	+	27260156	RDES	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.16799988988420544	[1390]	[1570,1699,1795,2181]	2	hSpCas9	negative selection	8553100
43070898	43070921	15	-	27260156	PC3	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.22639248937690692	[125]	[113,158,216,119]	5	hSpCas9	negative selection	8610100
43075073	43075096	15	-	27260156	PC3	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.20551635486940345	[371]	[227,333,453,326]	-4	hSpCas9	negative selection	8610101
43082637	43082660	15	-	27260156	PC3	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	-0.06595272193252533	[635]	[404,520,1012,675]	-1	hSpCas9	negative selection	8610102
43082679	43082702	15	-	27260156	PC3	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.0853482757532425	[523]	[356,367,916,505]	-2	hSpCas9	negative selection	8674349
43070833	43070856	15	-	27260156	PC3	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.3032724936225306	[378]	[226,297,485,282]	-6	hSpCas9	negative selection	8674350
43074983	43075006	15	+	27260156	PC3	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	-0.04329505446795889	[1390]	[806,1365,2045,1552]	-1	hSpCas9	negative selection	8674351
43070898	43070921	15	-	27260156	PATU8988T	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5888925078453922	[125]	[301,81,208,124]	8	hSpCas9	negative selection	8731351
43075073	43075096	15	-	27260156	PATU8988T	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.01612902735038363	[371]	[328,350,306,441]	0	hSpCas9	negative selection	8731352
43082637	43082660	15	-	27260156	PATU8988T	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.09956645958516619	[635]	[575,540,748,763]	1	hSpCas9	negative selection	8731353
43082679	43082702	15	-	27260156	PATU8988T	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.3774048757970407	[523]	[663,710,540,726]	6	hSpCas9	negative selection	8795600
43070833	43070856	15	-	27260156	PATU8988T	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.1583443001036587	[378]	[365,443,317,183]	-3	hSpCas9	negative selection	8795601
43074983	43075006	15	+	27260156	PATU8988T	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.28086160840153274	[1390]	[1194,1225,1778,2348]	5	hSpCas9	negative selection	8795602
43070898	43070921	15	-	27260156	T47D	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.4665595937130582	[125]	[268,166,177,200]	8	hSpCas9	negative selection	8852602
43075073	43075096	15	-	27260156	T47D	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.03407996369693811	[371]	[441,455,388,402]	0	hSpCas9	negative selection	8852603
43082637	43082660	15	-	27260156	T47D	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.24381798468197535	[635]	[798,823,915,976]	5	hSpCas9	negative selection	8852604
43082679	43082702	15	-	27260156	T47D	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.14759504232592197	[523]	[719,604,576,814]	3	hSpCas9	negative selection	8916851
43070833	43070856	15	-	27260156	T47D	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.2945906123658306	[378]	[359,347,405,324]	-6	hSpCas9	negative selection	8916852
43074983	43075006	15	+	27260156	T47D	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.03240191230633993	[1390]	[1611,1623,1555,1846]	0	hSpCas9	negative selection	8916853
43070898	43070921	15	-	27260156	SU8686	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.16749454340205316	[125]	[195,59,112,204]	3	hSpCas9	negative selection	8973853
43075073	43075096	15	-	27260156	SU8686	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.3875777783739568	[371]	[313,234,231,357]	-6	hSpCas9	negative selection	8973854
43082637	43082660	15	-	27260156	SU8686	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.13674746923932712	[635]	[476,738,725,874]	2	hSpCas9	negative selection	8973855
43082679	43082702	15	-	27260156	SU8686	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.34717494361584395	[523]	[623,727,555,734]	6	hSpCas9	negative selection	9038102
43070833	43070856	15	-	27260156	SU8686	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.1419485221996321	[378]	[286,472,305,269]	-2	hSpCas9	negative selection	9038103
43074983	43075006	15	+	27260156	SU8686	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.13036760571253225	[1390]	[1355,1325,1443,2023]	2	hSpCas9	negative selection	9038104
43070898	43070921	15	-	27260156	SKES1	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.4686217019262211	[125]	[186,219,152,144]	8	hSpCas9	negative selection	9095104
43075073	43075096	15	-	27260156	SKES1	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.46541678278220944	[371]	[282,361,269,180]	-8	hSpCas9	negative selection	9095105
43082637	43082660	15	-	27260156	SKES1	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.002411746328665365	[635]	[573,725,716,531]	0	hSpCas9	negative selection	9095106
43082679	43082702	15	-	27260156	SKES1	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	-0.03829508551750824	[523]	[516,620,402,505]	-1	hSpCas9	negative selection	9159353
43070833	43070856	15	-	27260156	SKES1	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.08692877260413218	[378]	[472,461,288,239]	-2	hSpCas9	negative selection	9159354
43074983	43075006	15	+	27260156	SKES1	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.11216093645269587	[1390]	[1640,1503,1526,1348]	2	hSpCas9	negative selection	9159355
43070898	43070921	15	-	27260156	TOV112D	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.29271761548869946	[125]	[100,227,88,211]	5	hSpCas9	negative selection	9216355
43075073	43075096	15	-	27260156	TOV112D	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.12270779572870288	[371]	[322,242,426,348]	-2	hSpCas9	negative selection	9216356
43082637	43082660	15	-	27260156	TOV112D	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.17337856950493646	[635]	[674,1256,566,507]	3	hSpCas9	negative selection	9216357
43082679	43082702	15	-	27260156	TOV112D	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.4826098245349328	[523]	[583,951,549,882]	8	hSpCas9	negative selection	9280604
43070833	43070856	15	-	27260156	TOV112D	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.8153570822367974	[378]	[243,303,137,200]	-9	hSpCas9	negative selection	9280605
43074983	43075006	15	+	27260156	TOV112D	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.0588490204902532	[1390]	[1440,1666,1204,1538]	1	hSpCas9	negative selection	9280606
43070898	43070921	15	-	27260156	TC71	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5735452573082169	[125]	[252,136,245,162]	9	hSpCas9	negative selection	9337606
43075073	43075096	15	-	27260156	TC71	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.06858152894360048	[371]	[485,276,382,371]	-2	hSpCas9	negative selection	9337607
43082637	43082660	15	-	27260156	TC71	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.16069477539752142	[635]	[739,783,759,764]	4	hSpCas9	negative selection	9337608
43082679	43082702	15	-	27260156	TC71	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.1349339494073561	[523]	[800,556,501,605]	3	hSpCas9	negative selection	9401855
43070833	43070856	15	-	27260156	TC71	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.14050042191480805	[378]	[403,263,327,485]	-4	hSpCas9	negative selection	9401856
43074983	43075006	15	+	27260156	TC71	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.04117583342896247	[1390]	[1548,1603,1423,1564]	1	hSpCas9	negative selection	9401857
43070898	43070921	15	-	27260156	TC32	viability	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.5795281429695389	[125]	[136,228,143,163]	8	hSpCas9	negative selection	9458857
43075073	43075096	15	-	27260156	TC32	viability	TATCAGATGCATACTTCTACTGG	UBR1	ENSG00000159459	-0.38512718309044025	[371]	[258,238,287,283]	-6	hSpCas9	negative selection	9458858
43082637	43082660	15	-	27260156	TC32	viability	TCATAAAAATCATCGTTACAAGG	UBR1	ENSG00000159459	0.7244843570963303	[635]	[1118,704,1225,969]	9	hSpCas9	negative selection	9458859
43082679	43082702	15	-	27260156	TC32	viability	TCCAACATGTGTACTCTGTATGG	UBR1	ENSG00000159459	0.3328482952943142	[523]	[545,620,669,620]	6	hSpCas9	negative selection	9523106
43070833	43070856	15	-	27260156	TC32	viability	ATGTCGTAGAAATGACTATATGG	UBR1	ENSG00000159459	-0.5956780509473212	[378]	[190,241,281,222]	-8	hSpCas9	negative selection	9523107
43074983	43075006	15	+	27260156	TC32	viability	TTTATAGTACCTGCTCTTCCAGG	UBR1	ENSG00000159459	0.10482507016949594	[1390]	[1421,907,1732,1739]	2	hSpCas9	negative selection	9523108
43054776	43054799	15	+	27869803	HPAFII	viability after 27 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.20098654428193563	[104]	[69,57,NaN]	1	hSpCas9	negative selection	9553673
43060092	43060115	15	-	27869803	HPAFII	viability after 27 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	1.3324937363808398	[155]	[235,181,NaN]	9	hSpCas9	negative selection	9553674
43067906	43067929	15	+	27869803	HPAFII	viability after 27 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.6689700206206645	[374]	[105,138,NaN]	-5	hSpCas9	negative selection	9553675
43070898	43070921	15	-	27869803	HPAFII	viability after 27 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.9315018893556894	[500]	[593,425,NaN]	7	hSpCas9	negative selection	9553676
43075067	43075090	15	-	27869803	HPAFII	viability after 27 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.6747920597218017	[249]	[277,152,NaN]	5	hSpCas9	negative selection	9553677
43106010	43106033	15	-	27869803	HPAFII	viability after 27 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	1.0451558399350516	[196]	[96,310,NaN]	8	hSpCas9	negative selection	9553678
43054776	43054799	15	+	27869803	HPAFII	viability after 15 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.3632178372534972	[104]	[183,120,NaN]	4	hSpCas9	negative selection	9636122
43060092	43060115	15	-	27869803	HPAFII	viability after 15 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.8837600947577005	[155]	[399,252,NaN]	8	hSpCas9	negative selection	9636123
43067906	43067929	15	+	27869803	HPAFII	viability after 15 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.2476635413374963	[374]	[344,335,NaN]	-3	hSpCas9	negative selection	9636124
43070898	43070921	15	-	27869803	HPAFII	viability after 15 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.7910034549243101	[500]	[1107,821,NaN]	8	hSpCas9	negative selection	9636125
43075067	43075090	15	-	27869803	HPAFII	viability after 15 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.18697106675772288	[249]	[414,237,NaN]	2	hSpCas9	negative selection	9636126
43106010	43106033	15	-	27869803	HPAFII	viability after 15 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	1.0443138479484535	[196]	[456,423,NaN]	9	hSpCas9	negative selection	9636127
43054776	43054799	15	+	27869803	ASPC1	viability after 36 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.5142693327455745	[308]	[194,159,118]	5	hSpCas9	negative selection	9718571
43060092	43060115	15	-	27869803	ASPC1	viability after 36 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	0.4131225227792493	[540]	[239,375,157]	4	hSpCas9	negative selection	9718572
43067906	43067929	15	+	27869803	ASPC1	viability after 36 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.3147219887944004	[878]	[406,131,557]	3	hSpCas9	negative selection	9718573
43070898	43070921	15	-	27869803	ASPC1	viability after 36 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	0.17475628971952695	[1264]	[655,657,255]	1	hSpCas9	negative selection	9718574
43075067	43075090	15	-	27869803	ASPC1	viability after 36 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	1.0709866968351338	[617]	[146,998,229]	8	hSpCas9	negative selection	9718575
43106010	43106033	15	-	27869803	ASPC1	viability after 36 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	1.8522594277382702	[433]	[341,1249,126]	9	hSpCas9	negative selection	9718576
43054776	43054799	15	+	27869803	PATU8988S	viability after 35 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.3392791149642287	[220]	[158,65,NaN]	4	hSpCas9	negative selection	9801020
43060092	43060115	15	-	27869803	PATU8988S	viability after 35 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.8507737105457458	[480]	[70,143,NaN]	-7	hSpCas9	negative selection	9801021
43067906	43067929	15	+	27869803	PATU8988S	viability after 35 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.22843427847850228	[771]	[217,312,NaN]	-2	hSpCas9	negative selection	9801022
43070898	43070921	15	-	27869803	PATU8988S	viability after 35 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.03005593268611162	[1209]	[380,573,NaN]	0	hSpCas9	negative selection	9801023
43075067	43075090	15	-	27869803	PATU8988S	viability after 35 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.06889454722594088	[495]	[167,212,NaN]	0	hSpCas9	negative selection	9801024
43106010	43106033	15	-	27869803	PATU8988S	viability after 35 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.39482048569984457	[360]	[260,120,NaN]	4	hSpCas9	negative selection	9801025
43054776	43054799	15	+	27869803	PATU8988S	viability after 31 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.02217935849554431	[220]	[125,42,NaN]	0	hSpCas9	negative selection	9883469
43060092	43060115	15	-	27869803	PATU8988S	viability after 31 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	-0.9582389139893834	[480]	[70,133,NaN]	-7	hSpCas9	negative selection	9883470
43067906	43067929	15	+	27869803	PATU8988S	viability after 31 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	0.049092951274462004	[771]	[343,285,NaN]	0	hSpCas9	negative selection	9883471
43070898	43070921	15	-	27869803	PATU8988S	viability after 31 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	-0.10201220027736091	[1209]	[361,560,NaN]	-1	hSpCas9	negative selection	9883472
43075067	43075090	15	-	27869803	PATU8988S	viability after 31 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	-0.2520394921287815	[495]	[140,197,NaN]	-3	hSpCas9	negative selection	9883473
43106010	43106033	15	-	27869803	PATU8988S	viability after 31 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.20069655576591433	[360]	[120,221,NaN]	2	hSpCas9	negative selection	9883474
43054776	43054799	15	+	27869803	HPAFII	viability after 35 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	-0.3500584190172946	[104]	[36,46,NaN]	-2	hSpCas9	negative selection	9965918
43060092	43060115	15	-	27869803	HPAFII	viability after 35 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	1.5648317663257485	[155]	[219,248,NaN]	9	hSpCas9	negative selection	9965919
43067906	43067929	15	+	27869803	HPAFII	viability after 35 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.29813667649100306	[374]	[128,182,NaN]	-2	hSpCas9	negative selection	9965920
43070898	43070921	15	-	27869803	HPAFII	viability after 35 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	1.3412362001782279	[500]	[699,577,NaN]	8	hSpCas9	negative selection	9965921
43075067	43075090	15	-	27869803	HPAFII	viability after 35 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.32354558295843816	[249]	[211,97,NaN]	2	hSpCas9	negative selection	9965922
43106010	43106033	15	-	27869803	HPAFII	viability after 35 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.4144185166092272	[196]	[83,187,NaN]	2	hSpCas9	negative selection	9965923
43054776	43054799	15	+	27869803	HPAFII	viability after 31 days	ATTTGTCCTGGCTATAACCCTGG	UBR1	ENSG00000159459	0.7219040686778354	[104]	[67,128,NaN]	5	hSpCas9	negative selection	10048367
43060092	43060115	15	-	27869803	HPAFII	viability after 31 days	GGTCGTCGGGCTGTTAAAGCGGG	UBR1	ENSG00000159459	1.463720341986789	[155]	[240,241,NaN]	9	hSpCas9	negative selection	10048368
43067906	43067929	15	+	27869803	HPAFII	viability after 31 days	CAATGGCAGTGGTATGCAACTGG	UBR1	ENSG00000159459	-0.5735186580245676	[374]	[94,191,NaN]	-4	hSpCas9	negative selection	10048369
43070898	43070921	15	-	27869803	HPAFII	viability after 31 days	ACGCTGTCCGTTGAATGAAGAGG	UBR1	ENSG00000159459	1.0948449616679465	[500]	[623,574,NaN]	7	hSpCas9	negative selection	10048370
43075067	43075090	15	-	27869803	HPAFII	viability after 31 days	ATGCATACTTCTACTGGAGGAGG	UBR1	ENSG00000159459	0.6131411994894304	[249]	[283,138,NaN]	4	hSpCas9	negative selection	10048371
43106010	43106033	15	-	27869803	HPAFII	viability after 31 days	TTCCCTCAAGATGGCGGACGAGG	UBR1	ENSG00000159459	0.9171492144675089	[196]	[80,347,NaN]	7	hSpCas9	negative selection	10048372
42976824	42976847	15	+	28162770	P31FUJ	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.24687738962610134	[205]	[203]	-2	hSpCas9	negative selection	10260721
42976804	42976827	15	+	28162770	P31FUJ	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.41128027271723533	[509]	[796]	4	hSpCas9	negative selection	10260722
43105974	43105997	15	-	28162770	P31FUJ	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.3542587621907755	[228]	[343]	4	hSpCas9	negative selection	10260723
43075036	43075059	15	-	28162770	P31FUJ	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.6020360140800975	[30]	[23]	-5	hSpCas9	negative selection	10260724
43047244	43047267	15	-	28162770	P31FUJ	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.42509181876062885	[359]	[567]	5	hSpCas9	negative selection	10260725
43030024	43030047	15	-	28162770	P31FUJ	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.1610115213463683	[97]	[102]	-1	hSpCas9	negative selection	10260726
43024950	43024973	15	+	28162770	P31FUJ	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.8440759822513823	[497]	[325]	-6	hSpCas9	negative selection	10260727
43007260	43007283	15	+	28162770	P31FUJ	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.40952276736554405	[398]	[352]	-4	hSpCas9	negative selection	10260728
43003867	43003890	15	-	28162770	P31FUJ	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.10284361028971091	[243]	[266]	-1	hSpCas9	negative selection	10260729
42977893	42977916	15	+	28162770	P31FUJ	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-0.135505003059464	[42]	[45]	-1	hSpCas9	negative selection	10260730
42976824	42976847	15	+	28162770	TF1	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10430087
42976804	42976827	15	+	28162770	TF1	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	NaN	[NaN]	[462]	1	hSpCas9	negative selection	10430088
43105974	43105997	15	-	28162770	TF1	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10430089
43075036	43075059	15	-	28162770	TF1	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10430090
43047244	43047267	15	-	28162770	TF1	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	NaN	[NaN]	[380]	1	hSpCas9	negative selection	10430091
43030024	43030047	15	-	28162770	TF1	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10430092
43024950	43024973	15	+	28162770	TF1	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10430093
43007260	43007283	15	+	28162770	TF1	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	NaN	[NaN]	[269]	1	hSpCas9	negative selection	10430094
43003867	43003890	15	-	28162770	TF1	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10430095
42977893	42977916	15	+	28162770	TF1	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10430096
42976824	42976847	15	+	28162770	SKM1	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.14019626926561	[57]	[112]	1	hSpCas9	negative selection	10599453
42976804	42976827	15	+	28162770	SKM1	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.50464880710776	[121]	[305]	5	hSpCas9	negative selection	10599454
43105974	43105997	15	-	28162770	SKM1	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.46093226524949305	[89]	[218]	4	hSpCas9	negative selection	10599455
43075036	43075059	15	-	28162770	SKM1	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10599456
43047244	43047267	15	-	28162770	SKM1	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.038135128886771064	[114]	[197]	0	hSpCas9	negative selection	10599457
43030024	43030047	15	-	28162770	SKM1	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10599458
43024950	43024973	15	+	28162770	SKM1	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.00191078803694	[144]	[127]	-6	hSpCas9	negative selection	10599459
43007260	43007283	15	+	28162770	SKM1	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.6323766928890063	[103]	[284]	6	hSpCas9	negative selection	10599460
43003867	43003890	15	-	28162770	SKM1	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.003968902202945546	[43]	[77]	0	hSpCas9	negative selection	10599461
42977893	42977916	15	+	28162770	SKM1	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.8220016980220062	[9]	[4]	-8	hSpCas9	negative selection	10599462
42976824	42976847	15	+	28162770	SKM1	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.14019626926561	[57]	[112]	1	hSpCas9	negative selection	10768819
42976804	42976827	15	+	28162770	SKM1	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.50464880710776	[121]	[305]	5	hSpCas9	negative selection	10768820
43105974	43105997	15	-	28162770	SKM1	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.46093226524949305	[89]	[218]	4	hSpCas9	negative selection	10768821
43075036	43075059	15	-	28162770	SKM1	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.684498174272071	[9]	[10]	-5	hSpCas9	negative selection	10768822
43047244	43047267	15	-	28162770	SKM1	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.038135128886771064	[114]	[197]	0	hSpCas9	negative selection	10768823
43030024	43030047	15	-	28162770	SKM1	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10768824
43024950	43024973	15	+	28162770	SKM1	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.00191078803694	[144]	[127]	-6	hSpCas9	negative selection	10768825
43007260	43007283	15	+	28162770	SKM1	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.6323766928890063	[103]	[284]	6	hSpCas9	negative selection	10768826
43003867	43003890	15	-	28162770	SKM1	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.003968902202945546	[43]	[77]	0	hSpCas9	negative selection	10768827
42977893	42977916	15	+	28162770	SKM1	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.8220016980220062	[9]	[4]	-8	hSpCas9	negative selection	10768828
42976824	42976847	15	+	28162770	PL21	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	1.20013961448932	[198]	[198]	8	hSpCas9	negative selection	10938185
42976804	42976827	15	+	28162770	PL21	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	-0.11971116536543336	[346]	[138]	-1	hSpCas9	negative selection	10938186
43105974	43105997	15	-	28162770	PL21	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.29147992602774586	[305]	[162]	2	hSpCas9	negative selection	10938187
43075036	43075059	15	-	28162770	PL21	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-4.121788480398043	[39]	[0]	-9	hSpCas9	negative selection	10938188
43047244	43047267	15	-	28162770	PL21	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.8365256167950341	[394]	[306]	7	hSpCas9	negative selection	10938189
43030024	43030047	15	-	28162770	PL21	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	0.1822177064920576	[80]	[39]	1	hSpCas9	negative selection	10938190
43024950	43024973	15	+	28162770	PL21	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.5256854220716857	[386]	[116]	-4	hSpCas9	negative selection	10938191
43007260	43007283	15	+	28162770	PL21	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.20795911894861963	[367]	[184]	1	hSpCas9	negative selection	10938192
43003867	43003890	15	-	28162770	PL21	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.5277142725178245	[203]	[127]	4	hSpCas9	negative selection	10938193
42977893	42977916	15	+	28162770	PL21	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	1.9138354293326791	[24]	[40]	9	hSpCas9	negative selection	10938194
42976824	42976847	15	+	28162770	P31FUJ	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.24687738962610134	[205]	[203]	-2	hSpCas9	negative selection	11107551
42976804	42976827	15	+	28162770	P31FUJ	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.41128027271723533	[509]	[796]	4	hSpCas9	negative selection	11107552
43105974	43105997	15	-	28162770	P31FUJ	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.3542587621907755	[228]	[343]	4	hSpCas9	negative selection	11107553
43075036	43075059	15	-	28162770	P31FUJ	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.6020360140800975	[30]	[23]	-5	hSpCas9	negative selection	11107554
43047244	43047267	15	-	28162770	P31FUJ	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.42509181876062885	[359]	[567]	5	hSpCas9	negative selection	11107555
43030024	43030047	15	-	28162770	P31FUJ	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.1610115213463683	[97]	[102]	-1	hSpCas9	negative selection	11107556
43024950	43024973	15	+	28162770	P31FUJ	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.8440759822513823	[497]	[325]	-6	hSpCas9	negative selection	11107557
43007260	43007283	15	+	28162770	P31FUJ	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.40952276736554405	[398]	[352]	-4	hSpCas9	negative selection	11107558
43003867	43003890	15	-	28162770	P31FUJ	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.10284361028971091	[243]	[266]	-1	hSpCas9	negative selection	11107559
42977893	42977916	15	+	28162770	P31FUJ	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-0.135505003059464	[42]	[45]	-1	hSpCas9	negative selection	11107560
42976824	42976847	15	+	28162770	OCIAML5	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.1659252357754735	[155]	[250]	-1	hSpCas9	negative selection	11276917
42976804	42976827	15	+	28162770	OCIAML5	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.681577152572179	[247]	[717]	6	hSpCas9	negative selection	11276918
43105974	43105997	15	-	28162770	OCIAML5	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.017875463834077454	[174]	[311]	0	hSpCas9	negative selection	11276919
43075036	43075059	15	-	28162770	OCIAML5	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-2.1739946657513594	[14]	[5]	-8	hSpCas9	negative selection	11276920
43047244	43047267	15	-	28162770	OCIAML5	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.36474481820915117	[221]	[515]	3	hSpCas9	negative selection	11276921
43030024	43030047	15	-	28162770	OCIAML5	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	0.4221083925749973	[42]	[103]	3	hSpCas9	negative selection	11276922
43024950	43024973	15	+	28162770	OCIAML5	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.6676419997265697	[285]	[324]	-4	hSpCas9	negative selection	11276923
43007260	43007283	15	+	28162770	OCIAML5	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	0.26809219217040103	[212]	[462]	2	hSpCas9	negative selection	11276924
43003867	43003890	15	-	28162770	OCIAML5	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.09160727403085445	[133]	[226]	0	hSpCas9	negative selection	11276925
42977893	42977916	15	+	28162770	OCIAML5	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	0.8260053342486406	[14]	[47]	7	hSpCas9	negative selection	11276926
42976824	42976847	15	+	28162770	EOL1	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.8068961829162616	[331]	[305]	7	hSpCas9	negative selection	11446283
42976804	42976827	15	+	28162770	EOL1	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.5669957669524507	[491]	[383]	5	hSpCas9	negative selection	11446284
43105974	43105997	15	-	28162770	EOL1	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.18572781334325628	[518]	[310]	1	hSpCas9	negative selection	11446285
43075036	43075059	15	-	28162770	EOL1	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.784403446426075	[84]	[25]	-5	hSpCas9	negative selection	11446286
43047244	43047267	15	-	28162770	EOL1	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.3957798103019914	[641]	[444]	3	hSpCas9	negative selection	11446287
43030024	43030047	15	-	28162770	EOL1	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	0.02184497292544929	[171]	[91]	0	hSpCas9	negative selection	11446288
43024950	43024973	15	+	28162770	EOL1	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	0.4638676067359784	[577]	[419]	4	hSpCas9	negative selection	11446289
43007260	43007283	15	+	28162770	EOL1	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.09392488850094421	[392]	[193]	0	hSpCas9	negative selection	11446290
43003867	43003890	15	-	28162770	EOL1	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.767827671571601	[222]	[68]	-5	hSpCas9	negative selection	11446291
42977893	42977916	15	+	28162770	EOL1	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	0.5460361483168046	[25]	[19]	5	hSpCas9	negative selection	11446292
42976824	42976847	15	+	28162770	MOLM13	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	0.8166931824233359	[350]	[446]	6	hSpCas9	negative selection	11615649
42976804	42976827	15	+	28162770	MOLM13	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.4353215190881481	[671]	[656]	3	hSpCas9	negative selection	11615650
43105974	43105997	15	-	28162770	MOLM13	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.7811352333321404	[399]	[496]	6	hSpCas9	negative selection	11615651
43075036	43075059	15	-	28162770	MOLM13	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	0.7194281485405432	[20]	[24]	5	hSpCas9	negative selection	11615652
43047244	43047267	15	-	28162770	MOLM13	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.3383297477756628	[488]	[446]	2	hSpCas9	negative selection	11615653
43030024	43030047	15	-	28162770	MOLM13	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	0.1580341189577914	[118]	[95]	1	hSpCas9	negative selection	11615654
43024950	43024973	15	+	28162770	MOLM13	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.4015265086452768	[474]	[129]	-6	hSpCas9	negative selection	11615655
43007260	43007283	15	+	28162770	MOLM13	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.23438047136038187	[492]	[302]	-1	hSpCas9	negative selection	11615656
43003867	43003890	15	-	28162770	MOLM13	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.8419550997671165	[249]	[323]	6	hSpCas9	negative selection	11615657
42977893	42977916	15	+	28162770	MOLM13	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	1.6605344594869746	[34]	[79]	9	hSpCas9	negative selection	11615658
42976824	42976847	15	+	28162770	HEL	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-1.0259454946183024	[336]	[105]	-6	hSpCas9	negative selection	11785015
42976804	42976827	15	+	28162770	HEL	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.5128085279552229	[417]	[381]	4	hSpCas9	negative selection	11785016
43105974	43105997	15	-	28162770	HEL	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.7202944662166784	[444]	[172]	-5	hSpCas9	negative selection	11785017
43075036	43075059	15	-	28162770	HEL	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-2.3572611679996434	[55]	[6]	-8	hSpCas9	negative selection	11785018
43047244	43047267	15	-	28162770	HEL	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.5116767955200839	[531]	[238]	-3	hSpCas9	negative selection	11785019
43030024	43030047	15	-	28162770	HEL	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-2.4580618087871353	[162]	[18]	-8	hSpCas9	negative selection	11785020
43024950	43024973	15	+	28162770	HEL	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-2.387008511393695	[440]	[53]	-8	hSpCas9	negative selection	11785021
43007260	43007283	15	+	28162770	HEL	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.13179591261357193	[401]	[234]	-1	hSpCas9	negative selection	11785022
43003867	43003890	15	-	28162770	HEL	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.6110177602454263	[185]	[77]	-4	hSpCas9	negative selection	11785023
42977893	42977916	15	+	28162770	HEL	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.357261167999643	[31]	[7]	-7	hSpCas9	negative selection	11785024
42976824	42976847	15	+	28162770	MV411	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.4824732858494803	[271]	[163]	-4	hSpCas9	negative selection	11954381
42976804	42976827	15	+	28162770	MV411	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.5280248502892381	[353]	[429]	5	hSpCas9	negative selection	11954382
43105974	43105997	15	-	28162770	MV411	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	-0.8148467274715675	[354]	[169]	-5	hSpCas9	negative selection	11954383
43075036	43075059	15	-	28162770	MV411	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.6150589254672898	[19]	[10]	-4	hSpCas9	negative selection	11954384
43047244	43047267	15	-	28162770	MV411	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	-0.4588312461605144	[402]	[246]	-3	hSpCas9	negative selection	11954385
43030024	43030047	15	-	28162770	MV411	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-1.9838879953236808	[107]	[22]	-8	hSpCas9	negative selection	11954386
43024950	43024973	15	+	28162770	MV411	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-1.4067876123754945	[383]	[121]	-7	hSpCas9	negative selection	11954387
43007260	43007283	15	+	28162770	MV411	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.5050790469179465	[341]	[202]	-4	hSpCas9	negative selection	11954388
43003867	43003890	15	-	28162770	MV411	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.5938647031981665	[171]	[95]	-4	hSpCas9	negative selection	11954389
42977893	42977916	15	+	28162770	MV411	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.1448798719959847	[20]	[7]	-6	hSpCas9	negative selection	11954390
42976824	42976847	15	+	28162770	MONOMAC1	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.011481193903477127	[152]	[173]	0	hSpCas9	negative selection	12123747
42976804	42976827	15	+	28162770	MONOMAC1	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.3467029909350894	[283]	[413]	3	hSpCas9	negative selection	12123748
43105974	43105997	15	-	28162770	MONOMAC1	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.7027989910150143	[163]	[305]	6	hSpCas9	negative selection	12123749
43075036	43075059	15	-	28162770	MONOMAC1	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-1.2414309664180074	[32]	[15]	-7	hSpCas9	negative selection	12123750
43047244	43047267	15	-	28162770	MONOMAC1	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.03428869904690213	[229]	[269]	0	hSpCas9	negative selection	12123751
43030024	43030047	15	-	28162770	MONOMAC1	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.7819993477807101	[47]	[31]	-6	hSpCas9	negative selection	12123752
43024950	43024973	15	+	28162770	MONOMAC1	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.9967381965737225	[234]	[134]	-7	hSpCas9	negative selection	12123753
43007260	43007283	15	+	28162770	MONOMAC1	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.02300744728450488	[194]	[219]	0	hSpCas9	negative selection	12123754
43003867	43003890	15	-	28162770	MONOMAC1	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	-0.9491093336159684	[95]	[56]	-6	hSpCas9	negative selection	12123755
42977893	42977916	15	+	28162770	MONOMAC1	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-0.9491093336159684	[31]	[18]	-6	hSpCas9	negative selection	12123756
42976824	42976847	15	+	28162770	OCIAML2	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.14112851064999785	[37]	[190]	-1	hSpCas9	negative selection	12293113
42976804	42976827	15	+	28162770	OCIAML2	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	0.5527026785884624	[68]	[560]	5	hSpCas9	negative selection	12293114
43105974	43105997	15	-	28162770	OCIAML2	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	1.0854199835637561	[41]	[493]	9	hSpCas9	negative selection	12293115
43075036	43075059	15	-	28162770	OCIAML2	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-0.8856673245210049	[7]	[23]	-6	hSpCas9	negative selection	12293116
43047244	43047267	15	-	28162770	OCIAML2	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.2723345095454881	[71]	[481]	2	hSpCas9	negative selection	12293117
43030024	43030047	15	-	28162770	OCIAML2	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.018933855384469123	[16]	[92]	0	hSpCas9	negative selection	12293118
43024950	43024973	15	+	28162770	OCIAML2	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	-0.48380521398989446	[54]	[217]	-4	hSpCas9	negative selection	12293119
43007260	43007283	15	+	28162770	OCIAML2	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.12382706171576963	[68]	[350]	-1	hSpCas9	negative selection	12293120
43003867	43003890	15	-	28162770	OCIAML2	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.41201322411968	[31]	[235]	4	hSpCas9	negative selection	12293121
42977893	42977916	15	+	28162770	OCIAML2	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	0.9078817980115685	[4]	[51]	8	hSpCas9	negative selection	12293122
42976824	42976847	15	+	28162770	OCIAML3	viability	GGGTCATCCCAATACAAGGATGG	UBR1	ENSG00000159459	-0.45865578742927693	[60]	[133]	-4	hSpCas9	negative selection	12462479
42976804	42976827	15	+	28162770	OCIAML3	viability	AAGAAGGCTGCAGATCAACAGGG	UBR1	ENSG00000159459	-0.11901798162813859	[108]	[302]	-1	hSpCas9	negative selection	12462480
43105974	43105997	15	-	28162770	OCIAML3	viability	TGAGAGGATGGAAATCAGCGCGG	UBR1	ENSG00000159459	0.44265083025468493	[67]	[278]	4	hSpCas9	negative selection	12462481
43075036	43075059	15	-	28162770	OCIAML3	viability	ACTGTGGAGACACAGAGGCATGG	UBR1	ENSG00000159459	-1.2314375609394546	[6]	[8]	-7	hSpCas9	negative selection	12462482
43047244	43047267	15	-	28162770	OCIAML3	viability	GGTTGGGCAACACATTGAAGTGG	UBR1	ENSG00000159459	0.15744428774212338	[108]	[366]	1	hSpCas9	negative selection	12462483
43030024	43030047	15	-	28162770	OCIAML3	viability	GGGAAATGTGACCAAAGAAGAGG	UBR1	ENSG00000159459	-0.7639326417664757	[26]	[47]	-5	hSpCas9	negative selection	12462484
43024950	43024973	15	+	28162770	OCIAML3	viability	GGGCAGAATTCAGGAGGTGGTGG	UBR1	ENSG00000159459	0.10276886372634408	[90]	[294]	1	hSpCas9	negative selection	12462485
43007260	43007283	15	+	28162770	OCIAML3	viability	AGAGTAGTCACTGACTGCTGGGG	UBR1	ENSG00000159459	-0.11517349046435033	[93]	[261]	-1	hSpCas9	negative selection	12462486
43003867	43003890	15	-	28162770	OCIAML3	viability	GGAACTTATACAGGAAGCTGTGG	UBR1	ENSG00000159459	0.835676634919082	[48]	[263]	7	hSpCas9	negative selection	12462487
42977893	42977916	15	+	28162770	OCIAML3	viability	AGATCTATAGACAGAAGGCATGG	UBR1	ENSG00000159459	-1.746010733769213	[9]	[8]	-8	hSpCas9	negative selection	12462488