Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 7343
  • Symbol: UBTF
  • Description: upstream binding transcription factor
DataSource: http://genomecrispr.dkfz.de/#!/results/UBTF

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
44216595 44216618 17 + 24336569 HL60 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 1.1803675581232402 [249] [1198] 8 hSpCas9 negative selection 2304940
44216622 44216645 17 + 24336569 HL60 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 -0.6152353196378348 [615] [850] -5 hSpCas9 negative selection 2304941
44216630 44216653 17 + 24336569 HL60 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -1.3396162850829438 [884] [739] -8 hSpCas9 negative selection 2304942
44216681 44216704 17 + 24336569 HL60 viability GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -1.8376980284998816 [401] [237] -9 hSpCas9 negative selection 2304943
44216686 44216709 17 + 24336569 HL60 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 1.6020622345758495 [65] [423] 9 hSpCas9 negative selection 2304944
44216697 44216720 17 - 24336569 HL60 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -1.171962966557993 [772] [725] -8 hSpCas9 negative selection 2304945
44218185 44218208 17 + 24336569 HL60 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 2.4420978554281167 [29] [344] 9 hSpCas9 negative selection 2304946
44218222 44218245 17 - 24336569 HL60 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 0.22401831286073146 [546] [1351] 2 hSpCas9 negative selection 2304947
44216595 44216618 17 + 24336569 KBM7 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 0.12353565768226837 [662] [1969] 1 hSpCas9 negative selection 2372117
44216622 44216645 17 + 24336569 KBM7 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 -0.15372605327423816 [466] [1144] -1 hSpCas9 negative selection 2372118
44216630 44216653 17 + 24336569 KBM7 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -2.275851820027749 [1510] [850] -8 hSpCas9 negative selection 2372119
44216681 44216704 17 + 24336569 KBM7 viability GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -8.58371588453491 [421] [2] -9 hSpCas9 negative selection 2372120
44216686 44216709 17 + 24336569 KBM7 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -0.7899025121873158 [186] [294] -6 hSpCas9 negative selection 2372121
44216697 44216720 17 - 24336569 KBM7 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -4.011582078634392 [614] [103] -9 hSpCas9 negative selection 2372122
44218185 44218208 17 + 24336569 KBM7 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 -0.10932293175751973 [122] [310] -1 hSpCas9 negative selection 2372123
44218222 44218245 17 - 24336569 KBM7 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 -0.008249879146160377 [610] [1656] 0 hSpCas9 negative selection 2372124
44221002 44221025 17 - 25494202 A375 resistance to PLX-4720 (puromycin) AGGCGAGGCCGGGGTGGCCCGGG UBTF ENSG00000108312 -1.9205379422287652 [3,213] [0,10] -9 dCas9-VP64 positive selection 2392808
44221054 44221077 17 - 25494202 A375 resistance to PLX-4720 (puromycin) GCAGTGGGAGGGAAGGGGTGAGG UBTF ENSG00000108312 -0.13298031259192555 [2,31] [1,3] 0 dCas9-VP64 positive selection 2392809
44220956 44220979 17 - 25494202 A375 resistance to PLX-4720 (puromycin) TGACGGGCAAGCGCTCGGAGCGG UBTF ENSG00000108312 3.14856279801916 [2,1] [1,6] 8 dCas9-VP64 positive selection 2392810
44219766 44219789 17 + 25494202 A375 resistance to PLX-4720 (puromycin) CGCCGGAGCGGGGAGGAGGAGGG UBTF ENSG00000108312 1.3365886810672052 [5,245] [2,144] 5 dCas9-VP64 positive selection 2392811
44219845 44219868 17 - 25494202 A375 resistance to PLX-4720 (puromycin) CGGTGTGCGCTCTACGGGGAAGG UBTF ENSG00000108312 -0.2328352296778342 [145,85] [2,40] -1 dCas9-VP64 positive selection 2392812
44219808 44219831 17 + 25494202 A375 resistance to PLX-4720 (puromycin) GGGAGGGGGGGCGGGAGAAGCGG UBTF ENSG00000108312 1.8976068686633374 [0,3] [0,2] 6 dCas9-VP64 positive selection 2392813
44221002 44221025 17 - 25494202 A375 resistance to PLX-4720 (zeocin) AGGCGAGGCCGGGGTGGCCCGGG UBTF ENSG00000108312 0.8509452146539358 [8,81] [3,45] 5 dCas9-VP64 positive selection 2488063
44221054 44221077 17 - 25494202 A375 resistance to PLX-4720 (zeocin) GCAGTGGGAGGGAAGGGGTGAGG UBTF ENSG00000108312 0.3461565508858312 [82,63] [43,16] 2 dCas9-VP64 positive selection 2488064
44220956 44220979 17 - 25494202 A375 resistance to PLX-4720 (zeocin) TGACGGGCAAGCGCTCGGAGCGG UBTF ENSG00000108312 1.6927124495223103 [26,8] [32,5] 8 dCas9-VP64 positive selection 2488065
44219766 44219789 17 + 25494202 A375 resistance to PLX-4720 (zeocin) CGCCGGAGCGGGGAGGAGGAGGG UBTF ENSG00000108312 0.4337240889422119 [423,24] [176,28] 3 dCas9-VP64 positive selection 2488066
44219845 44219868 17 - 25494202 A375 resistance to PLX-4720 (zeocin) CGGTGTGCGCTCTACGGGGAAGG UBTF ENSG00000108312 -1.8091280435642925 [221,84] [22,4] -9 dCas9-VP64 positive selection 2488067
44219808 44219831 17 + 25494202 A375 resistance to PLX-4720 (zeocin) GGGAGGGGGGGCGGGAGAAGCGG UBTF ENSG00000108312 -0.18589557295117443 [62,17] [15,6] -2 dCas9-VP64 positive selection 2488068
44218185 44218208 17 + 27260157 DLD1 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 0.501769238046978 [] [] 8 hSpCas9 negative selection 2575278
44216595 44216618 17 + 27260157 DLD1 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 -2.86719494923586 [] [] -9 hSpCas9 negative selection 2577098
44221276 44221299 17 + 27260157 DLD1 viability AAGCTCTGCAGCGCCCGACCCGG UBTF ENSG00000108312 0.353617375778771 [] [] 4 hSpCas9 negative selection 2582652
44221249 44221272 17 - 27260157 DLD1 viability GGCTTTCAACCCGCGCTCGCCGG UBTF ENSG00000108312 -0.164400454175307 [] [] -1 hSpCas9 negative selection 2604197
44216622 44216645 17 + 27260157 DLD1 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 0.449057138726931 [] [] 7 hSpCas9 negative selection 2610544
44221372 44221395 17 - 27260157 DLD1 viability CCACCAAGCGACCGGCTGATTGG UBTF ENSG00000108312 0.241435755025086 [] [] 4 hSpCas9 negative selection 2613207
44220855 44220878 17 + 27260157 DLD1 viability GAGATGGCGAAGCGGAGCGACGG UBTF ENSG00000108312 -0.00861713678730929 [] [] 0 hSpCas9 negative selection 2613365
44216630 44216653 17 + 27260157 DLD1 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -1.86913543200456 [] [] -8 hSpCas9 negative selection 2615813
44220839 44220862 17 + 27260157 DLD1 viability TCGCCAGACAAAGCCCGAGATGG UBTF ENSG00000108312 -0.78416657282569 [] [] -6 hSpCas9 negative selection 2616921
44218222 44218245 17 - 27260157 DLD1 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 1.44567306685466 [] [] 9 hSpCas9 negative selection 2617412
44216686 44216709 17 + 27260157 DLD1 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -1.74772484262605 [] [] -8 hSpCas9 negative selection 2643824
44216697 44216720 17 - 27260157 DLD1 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -3.37247950507229 [] [] -9 hSpCas9 negative selection 2646694
44220842 44220865 17 - 27260157 DLD1 viability TCGCCATCTCGGGCTTTGTCTGG UBTF ENSG00000108312 -1.06569656690893 [] [] -7 hSpCas9 negative selection 2648700
44221372 44221395 17 + 27260157 DLD1 viability CCAATCAGCCGGTCGCTTGGTGG UBTF ENSG00000108312 -0.939499510424026 [] [] -6 hSpCas9 negative selection 2649479
44218185 44218208 17 + 27260157 HT1080 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 -0.799536752166862 [] [] -8 hSpCas9 negative selection 2651408
44216595 44216618 17 + 27260157 HT1080 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 -3.54997647544106 [] [] -9 hSpCas9 negative selection 2653228
44221276 44221299 17 + 27260157 HT1080 viability AAGCTCTGCAGCGCCCGACCCGG UBTF ENSG00000108312 0.692347259906661 [] [] 6 hSpCas9 negative selection 2658782
44221249 44221272 17 - 27260157 HT1080 viability GGCTTTCAACCCGCGCTCGCCGG UBTF ENSG00000108312 -0.149177644094115 [] [] 0 hSpCas9 negative selection 2680327
44216622 44216645 17 + 27260157 HT1080 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 0.475547234823699 [] [] 4 hSpCas9 negative selection 2686674
44221372 44221395 17 - 27260157 HT1080 viability CCACCAAGCGACCGGCTGATTGG UBTF ENSG00000108312 0.812037352153838 [] [] 7 hSpCas9 negative selection 2689337
44220855 44220878 17 + 27260157 HT1080 viability GAGATGGCGAAGCGGAGCGACGG UBTF ENSG00000108312 0.20422267923659 [] [] 2 hSpCas9 negative selection 2689495
44216630 44216653 17 + 27260157 HT1080 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -1.50738454893272 [] [] -9 hSpCas9 negative selection 2691943
44220839 44220862 17 + 27260157 HT1080 viability TCGCCAGACAAAGCCCGAGATGG UBTF ENSG00000108312 -0.272215749217417 [] [] -4 hSpCas9 negative selection 2693051
44218222 44218245 17 - 27260157 HT1080 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 0.515902770082822 [] [] 4 hSpCas9 negative selection 2693542
44216686 44216709 17 + 27260157 HT1080 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -3.11164478472887 [] [] -9 hSpCas9 negative selection 2719954
44216697 44216720 17 - 27260157 HT1080 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -2.7886055774565 [] [] -9 hSpCas9 negative selection 2722824
44220842 44220865 17 - 27260157 HT1080 viability TCGCCATCTCGGGCTTTGTCTGG UBTF ENSG00000108312 -0.31378194053789 [] [] -7 hSpCas9 negative selection 2724830
44221372 44221395 17 + 27260157 HT1080 viability CCAATCAGCCGGTCGCTTGGTGG UBTF ENSG00000108312 -1.21566841734729 [] [] -8 hSpCas9 negative selection 2725609
44218185 44218208 17 + 27260157 MKN45 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 0.215798856601446 [] [] 5 hSpCas9 negative selection 2727538
44216595 44216618 17 + 27260157 MKN45 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 -2.50039881518787 [] [] -9 hSpCas9 negative selection 2729358
44221276 44221299 17 + 27260157 MKN45 viability AAGCTCTGCAGCGCCCGACCCGG UBTF ENSG00000108312 0.588057404419947 [] [] 7 hSpCas9 negative selection 2734912
44221249 44221272 17 - 27260157 MKN45 viability GGCTTTCAACCCGCGCTCGCCGG UBTF ENSG00000108312 -0.458868314720048 [] [] -6 hSpCas9 negative selection 2756457
44216622 44216645 17 + 27260157 MKN45 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 0.408708690639923 [] [] 6 hSpCas9 negative selection 2762804
44221372 44221395 17 - 27260157 MKN45 viability CCACCAAGCGACCGGCTGATTGG UBTF ENSG00000108312 0.364724856090761 [] [] 6 hSpCas9 negative selection 2765467
44220855 44220878 17 + 27260157 MKN45 viability GAGATGGCGAAGCGGAGCGACGG UBTF ENSG00000108312 0.400141326494291 [] [] 6 hSpCas9 negative selection 2765625
44216630 44216653 17 + 27260157 MKN45 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -1.24877407661776 [] [] -8 hSpCas9 negative selection 2768073
44220839 44220862 17 + 27260157 MKN45 viability TCGCCAGACAAAGCCCGAGATGG UBTF ENSG00000108312 -0.0968437163002879 [] [] 0 hSpCas9 negative selection 2769181
44218222 44218245 17 - 27260157 MKN45 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 1.18321200152739 [] [] 8 hSpCas9 negative selection 2769672
44216686 44216709 17 + 27260157 MKN45 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -1.34141360511145 [] [] -8 hSpCas9 negative selection 2796084
44216697 44216720 17 - 27260157 MKN45 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -2.43833597428783 [] [] -9 hSpCas9 negative selection 2798954
44220842 44220865 17 - 27260157 MKN45 viability TCGCCATCTCGGGCTTTGTCTGG UBTF ENSG00000108312 -0.869485034414138 [] [] -7 hSpCas9 negative selection 2800960
44221372 44221395 17 + 27260157 MKN45 viability CCAATCAGCCGGTCGCTTGGTGG UBTF ENSG00000108312 -0.590697072976393 [] [] -6 hSpCas9 negative selection 2801739
44218185 44218208 17 + 27260157 RKO viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 0.0673052211447011 [] [] 0 hSpCas9 negative selection 2803668
44216595 44216618 17 + 27260157 RKO viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 -3.31827052777136 [] [] -9 hSpCas9 negative selection 2805488
44221276 44221299 17 + 27260157 RKO viability AAGCTCTGCAGCGCCCGACCCGG UBTF ENSG00000108312 1.73370636233221 [] [] 9 hSpCas9 negative selection 2811042
44221249 44221272 17 - 27260157 RKO viability GGCTTTCAACCCGCGCTCGCCGG UBTF ENSG00000108312 -1.15728291901254 [] [] -8 hSpCas9 negative selection 2832587
44216622 44216645 17 + 27260157 RKO viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 -1.72137935033478 [] [] -9 hSpCas9 negative selection 2838934
44221372 44221395 17 - 27260157 RKO viability CCACCAAGCGACCGGCTGATTGG UBTF ENSG00000108312 1.22449468105862 [] [] 9 hSpCas9 negative selection 2841597
44220855 44220878 17 + 27260157 RKO viability GAGATGGCGAAGCGGAGCGACGG UBTF ENSG00000108312 0.47269256014991 [] [] 2 hSpCas9 negative selection 2841755
44216630 44216653 17 + 27260157 RKO viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -1.57606958041569 [] [] -9 hSpCas9 negative selection 2844203
44220839 44220862 17 + 27260157 RKO viability TCGCCAGACAAAGCCCGAGATGG UBTF ENSG00000108312 0.638880619336437 [] [] 3 hSpCas9 negative selection 2845311
44218222 44218245 17 - 27260157 RKO viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 0.876639530172619 [] [] 8 hSpCas9 negative selection 2845802
44216686 44216709 17 + 27260157 RKO viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -4.51786093003016 [] [] -9 hSpCas9 negative selection 2872214
44216697 44216720 17 - 27260157 RKO viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -3.65708081136387 [] [] -9 hSpCas9 negative selection 2875084
44220842 44220865 17 - 27260157 RKO viability TCGCCATCTCGGGCTTTGTCTGG UBTF ENSG00000108312 -1.01054246897225 [] [] -8 hSpCas9 negative selection 2877090
44221372 44221395 17 + 27260157 RKO viability CCAATCAGCCGGTCGCTTGGTGG UBTF ENSG00000108312 -1.46652453171189 [] [] -8 hSpCas9 negative selection 2877869
44218185 44218208 17 + 27260157 SF268 viability GGCGGCCATTTCCAGGTCTGTGG UBTF ENSG00000108312 0.722617700948001 [] [] 8 hSpCas9 negative selection 2879798
44216595 44216618 17 + 27260157 SF268 viability TTCCCAGTCCATGTGTGATTCGG UBTF ENSG00000108312 -3.91096580142747 [] [] -9 hSpCas9 negative selection 2881618
44221276 44221299 17 + 27260157 SF268 viability AAGCTCTGCAGCGCCCGACCCGG UBTF ENSG00000108312 0.402046805783915 [] [] 4 hSpCas9 negative selection 2887172
44221249 44221272 17 - 27260157 SF268 viability GGCTTTCAACCCGCGCTCGCCGG UBTF ENSG00000108312 -0.445306959334051 [] [] -3 hSpCas9 negative selection 2908717
44216622 44216645 17 + 27260157 SF268 viability TTTGAACTTGGAGCTGTCATTGG UBTF ENSG00000108312 -0.336459759832842 [] [] -3 hSpCas9 negative selection 2915064
44221372 44221395 17 - 27260157 SF268 viability CCACCAAGCGACCGGCTGATTGG UBTF ENSG00000108312 0.229825836067987 [] [] 3 hSpCas9 negative selection 2917727
44220855 44220878 17 + 27260157 SF268 viability GAGATGGCGAAGCGGAGCGACGG UBTF ENSG00000108312 -0.0855679652950134 [] [] 0 hSpCas9 negative selection 2917885
44216630 44216653 17 + 27260157 SF268 viability TGGAGCTGTCATTGGATGGAAGG UBTF ENSG00000108312 -0.690595064458595 [] [] -5 hSpCas9 negative selection 2920333
44220839 44220862 17 + 27260157 SF268 viability TCGCCAGACAAAGCCCGAGATGG UBTF ENSG00000108312 -0.374159969622692 [] [] -3 hSpCas9 negative selection 2921441
44218222 44218245 17 - 27260157 SF268 viability CTGGACAGCTGGAGGATGAACGG UBTF ENSG00000108312 1.14249259071 [] [] 9 hSpCas9 negative selection 2921932
44216686 44216709 17 + 27260157 SF268 viability TCTTCCTGGGACCAACGGTCTGG UBTF ENSG00000108312 -2.20736901718041 [] [] -9 hSpCas9 negative selection 2948344
44216697 44216720 17 - 27260157 SF268 viability GTTACTCTTTACCAGACCGTTGG UBTF ENSG00000108312 -3.57533381961711 [] [] -9 hSpCas9 negative selection 2951214
44220842 44220865 17 - 27260157 SF268 viability TCGCCATCTCGGGCTTTGTCTGG UBTF ENSG00000108312 -0.425063580649048 [] [] -3 hSpCas9 negative selection 2953220
44221372 44221395 17 + 27260157 SF268 viability CCAATCAGCCGGTCGCTTGGTGG UBTF ENSG00000108312 -0.771267095598715 [] [] -6 hSpCas9 negative selection 2953999
44216682 44216705 17 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -0.4727476041871369 [3,3] [2,0] -6 hSpCas9 positive selection 3030735
44216682 44216705 17 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -0.69384948759548 [3,3] [1,0] -8 hSpCas9 positive selection 3098593
44216690 44216713 - 24336571 A375 resistance to PLX after 7 days TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.1044590894587849 [34,30] [32,27] -3 hSpCas9 positive selection 3154099
44216690 44216713 - 24336571 A375 resistance to PLX after 14 days TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.7897553170832621 [33,31] [7,8] -8 hSpCas9 positive selection 3211892
44216690 44216713 - 24336571 A375 viability after 7 days TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.024697921263660882 [33] [34,30] 0 hSpCas9 negative selection 3269685
44216690 44216713 - 24336571 A375 viability after 14 days TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.03207541651969481 [33] [33,31] 0 hSpCas9 negative selection 3327478
44216690 44216713 17 - 27383988 293T resistance to West Nile virus (flavivirus) TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 1.672363710724679 [47,47] [0,0] 6 hSpCas9 positive selection 3400154
44216681 44216704 17 + 26780180 HT29 viability (Avana library 4 designs) GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 5.67320722877246 [] [] 9 hSpCas9 negative selection 3469672
44216681 44216704 17 + 26780180 A375 viability (Avana lentiCRISPRv2) GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -7.17510155203192 [] [] -6 hSpCas9 negative selection 3575017
44216681 44216704 17 + 26780180 A375 viability (Avana lentiGuide) GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 27.6532772268007 [] [] 9 hSpCas9 negative selection 3683676
44216681 44216704 17 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -0.1921038649428397 [6] [5,4] -3 hSpCas9 positive selection 3792283
44216681 44216704 17 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCATGTCTTCCTGGGACCAACGG UBTF ENSG00000108312 -0.970108905380735 [6] [3,1] -8 hSpCas9 positive selection 3900890
44216603 44216626 17 - 26780180 A375 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 2.08906112873047 [] [] 9 hSpCas9 negative selection 4009996
44216690 44216713 17 - 26780180 A375 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 1.78607775290179 [] [] 9 hSpCas9 negative selection 4009997
44216603 44216626 17 - 26780180 HT29 viability (GeCKOv2 library) CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 2.04761603778813 [] [] 9 hSpCas9 negative selection 4117962
44216690 44216713 17 - 26780180 HT29 viability (GeCKOv2 library) TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 2.26202524237806 [] [] 9 hSpCas9 negative selection 4117963
44216690 44216713 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.024753772531058427 [4] [2,2] 0 hSpCas9 positive selection 4180773
44216690 44216713 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.37947700786716504 [4] [4,3,4,0] 3 hSpCas9 positive selection 4244795
44216603 44216626 17 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.48477548627962463 [3] [2,0] -8 hSpCas9 positive selection 4306391
44216690 44216713 17 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -1.1087118174727046 [2] [0,0] -9 hSpCas9 positive selection 4370638
44216611 44216633 17 + 27760321 OCIAML3 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -0.41923790154292284 [294,296] [115,248] -4 hSpCas9 negative selection 4452011
44216611 44216633 17 + 27760321 OCIAML2 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -0.6330666465439175 [294,296] [182,117] -6 hSpCas9 negative selection 4535474
44216611 44216633 17 + 27760321 MV411 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 0.8734028795192681 [294,296] [16,872] 6 hSpCas9 negative selection 4618937
44216611 44216633 17 + 27760321 HL60 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 0.3461866005855284 [294,296] [240,379] 4 hSpCas9 negative selection 4702400
44216611 44216633 17 + 27760321 HT1080 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -6.71938476969259 [296,231] [0,0] -9 hSpCas9 negative selection 4785863
44216611 44216633 17 + 27760321 HT29 viability after 7 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -0.31181458379432136 [296,231] [356,316,162] -4 hSpCas9 negative selection 4869326
44216611 44216633 17 + 27760321 HT29 viability after 25 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -2.8730219404536697 [296,231] [12,66,45] -8 hSpCas9 negative selection 4952789
44216611 44216633 17 + 27760321 HT29 viability after 22 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -2.5486626555953644 [296,231] [2,10,144] -8 hSpCas9 negative selection 5036252
44216611 44216633 17 + 27760321 HT29 viability after 19 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -2.5372268544078085 [296,231] [106,54,1] -8 hSpCas9 negative selection 5119715
44216611 44216633 17 + 27760321 HT29 viability after 16 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -2.5024529656422008 [296,231] [106,7,47] -8 hSpCas9 negative selection 5203178
44216611 44216633 17 + 27760321 HT29 viability after 13 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -1.4095204547967874 [296,231] [57,195,93] -8 hSpCas9 negative selection 5286641
44216611 44216633 17 + 27760321 HT29 viability after 10 days GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -1.2949883244509266 [296,231] [175,180,49] -8 hSpCas9 negative selection 5370104
44216611 44216633 17 + 27760321 MOLM13 viability GATTCGGTGGTTTTGAACTTGG UBTF ENSG00000108312 -3.420145288792153 [294,296] [26,5] -9 hSpCas9 negative selection 5453567
44220412 44220435 17 - 27661255 K562 viability GTGCGTGCGCCCCAAACCAGCGG UBTF ENSG00000108312 0.12573907483237745 [424,429] [385,360] 4 dCas9-KRAB negative selection 5521291
44216603 44216626 17 - 27260156 BXPC3 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.23431051048348334 [535] [289,608,605,402] -5 hSpCas9 negative selection 5578851
44216690 44216713 17 - 27260156 BXPC3 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.18747772552960928 [293] [202,239,308,344] -4 hSpCas9 negative selection 5643098
44216603 44216626 17 - 27260156 A673 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.2822266141346314 [535] [637,504,365,626] -6 hSpCas9 negative selection 5700102
44216690 44216713 17 - 27260156 A673 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.25926393679039184 [293] [289,284,319,282] -6 hSpCas9 negative selection 5764349
44216603 44216626 17 - 27260156 A375 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.09185500875064304 [535] [570,747,512,542] -1 hSpCas9 negative selection 5821353
44216690 44216713 17 - 27260156 A375 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.5131290910482119 [293] [257,231,234,235] -6 hSpCas9 negative selection 5885600
44216603 44216626 17 - 27260156 COLO741 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 0.012489932288149791 [535] [744,578,746] 0 hSpCas9 negative selection 5942604
44216690 44216713 17 - 27260156 COLO741 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.5514245033304465 [293] [267,267,234] -8 hSpCas9 negative selection 6006851
44216603 44216626 17 - 27260156 CAL120 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.12188396494745353 [535] [488,719,610] -2 hSpCas9 negative selection 6063855
44216690 44216713 17 - 27260156 CAL120 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.3278765282884447 [293] [198,347,312] -5 hSpCas9 negative selection 6128102
44216603 44216626 17 - 27260156 CADOES1 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.3112346488734994 [535] [387,429,417,369] -5 hSpCas9 negative selection 6185106
44216690 44216713 17 - 27260156 CADOES1 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.38984924025524925 [293] [138,271,267,153] -6 hSpCas9 negative selection 6249353
44216603 44216626 17 - 27260156 EWS502 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.5426388100337258 [535] [404,446,457,232] -7 hSpCas9 negative selection 6306357
44216690 44216713 17 - 27260156 EWS502 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.4225024032749308 [293] [192,275,220,241] -6 hSpCas9 negative selection 6370604
44216603 44216626 17 - 27260156 EW8 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.25356844748627727 [535] [390,388,277,415] -5 hSpCas9 negative selection 6427608
44216690 44216713 17 - 27260156 EW8 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.23030547554750025 [293] [223,153,201,233] -4 hSpCas9 negative selection 6491855
44216603 44216626 17 - 27260156 CORL105 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 3.814764726054971 [535] [31279,1193,1488,1160] 9 hSpCas9 negative selection 6548859
44216690 44216713 17 - 27260156 CORL105 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.25742274204575066 [293] [331,234,261,320] -5 hSpCas9 negative selection 6613106
44216603 44216626 17 - 27260156 HS294T viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.03223892426098554 [535] [153,234,229,192] 0 hSpCas9 negative selection 6670110
44216690 44216713 17 - 27260156 HS294T viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.8864367877341283 [293] [27,59,79,84] -8 hSpCas9 negative selection 6734357
44216603 44216626 17 - 27260156 HCC44 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.6580668581138049 [535] [277,433,511,316] -7 hSpCas9 negative selection 6791361
44216690 44216713 17 - 27260156 HCC44 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.08510250075310422 [293] [283,301,281,522] 1 hSpCas9 negative selection 6855608
44216603 44216626 17 - 27260156 G402 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.2589922837585085 [535] [531,363,508,755] -3 hSpCas9 negative selection 6912612
44216690 44216713 17 - 27260156 G402 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.4780711739485991 [293] [396,158,216,269] -5 hSpCas9 negative selection 6976859
44216603 44216626 17 - 27260156 L33 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 0.21711102943156174 [535] [627,235,354,721] 5 hSpCas9 negative selection 7033863
44216690 44216713 17 - 27260156 L33 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.0011986701162045588 [293] [310,133,164,275] 0 hSpCas9 negative selection 7098110
44216603 44216626 17 - 27260156 K562 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.3982195937924684 [535] [544,612,163,170] -5 hSpCas9 negative selection 7155114
44216690 44216713 17 - 27260156 K562 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.03373307895143207 [293] [275,211,507,89] 0 hSpCas9 negative selection 7219361
44216603 44216626 17 - 27260156 HT29 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.6348697784679229 [535] [476,459,458,301] -8 hSpCas9 negative selection 7276365
44216690 44216713 17 - 27260156 HT29 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.30820679152104913 [293] [288,291,311,262] -5 hSpCas9 negative selection 7340612
44216603 44216626 17 - 27260156 MHHES1 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.5861212359965171 [535] [342,517,454,309] -8 hSpCas9 negative selection 7397616
44216690 44216713 17 - 27260156 MHHES1 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.517297013563205 [293] [167,295,279,185] -7 hSpCas9 negative selection 7461863
44216603 44216626 17 - 27260156 MEWO viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.24053834509720587 [535] [602,393,310] -5 hSpCas9 negative selection 7518867
44216690 44216713 17 - 27260156 MEWO viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.3050659475819085 [293] [170,189,296] -6 hSpCas9 negative selection 7583114
44216603 44216626 17 - 27260156 LNCAPCLONEFGC viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.18181795424234204 [535] [392,440,557,338] -3 hSpCas9 negative selection 7640118
44216690 44216713 17 - 27260156 LNCAPCLONEFGC viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.12985774273253292 [293] [309,255,254,340] 2 hSpCas9 negative selection 7704365
44216603 44216626 17 - 27260156 PANC0327 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.24033133980840343 [535] [617,276,361,388] -4 hSpCas9 negative selection 7761369
44216690 44216713 17 - 27260156 PANC0327 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.11745349608253641 [293] [304,241,220,199] -2 hSpCas9 negative selection 7825616
44216603 44216626 17 - 27260156 NCIH2009 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.6070326871119522 [535] [616,488,392] -6 hSpCas9 negative selection 7882620
44216690 44216713 17 - 27260156 NCIH2009 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.7902768891856827 [293] [222,307,176] -7 hSpCas9 negative selection 7946867
44216603 44216626 17 - 27260156 NCIH1373 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -1.0836955604686762 [535] [521,190,214,65] -8 hSpCas9 negative selection 8003871
44216690 44216713 17 - 27260156 NCIH1373 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.02391811971837776 [293] [267,483,198,95] 0 hSpCas9 negative selection 8068118
44216603 44216626 17 - 27260156 PATU8902 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.18554726621568204 [535] [437,727,477,1075] -2 hSpCas9 negative selection 8125122
44216690 44216713 17 - 27260156 PATU8902 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.03717559407621385 [293] [441,721,234,214] 0 hSpCas9 negative selection 8189369
44216603 44216626 17 - 27260156 PANC1 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -1.011512722658173 [535] [257,370,158,160] -8 hSpCas9 negative selection 8246373
44216690 44216713 17 - 27260156 PANC1 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.29249639865300925 [293] [231,315,211,100] -5 hSpCas9 negative selection 8310620
44216603 44216626 17 - 27260156 PANC0813 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.5707978895981209 [535] [461,422,454,361] -7 hSpCas9 negative selection 8367624
44216690 44216713 17 - 27260156 PANC0813 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.03291406974847311 [293] [337,300,357,351] 0 hSpCas9 negative selection 8431871
44216603 44216626 17 - 27260156 RDES viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.45982904272408676 [535] [382,460,465,487] -7 hSpCas9 negative selection 8488875
44216690 44216713 17 - 27260156 RDES viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.08387144952103387 [293] [278,283,349,565] 1 hSpCas9 negative selection 8553122
44216603 44216626 17 - 27260156 PC3 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 0.08687752448756697 [535] [360,507,954,637] 2 hSpCas9 negative selection 8610126
44216690 44216713 17 - 27260156 PC3 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 0.3012590394304443 [293] [151,247,780,507] 6 hSpCas9 negative selection 8674373
44216603 44216626 17 - 27260156 PATU8988T viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.6748619471397155 [535] [236,301,323,441] -8 hSpCas9 negative selection 8731377
44216690 44216713 17 - 27260156 PATU8988T viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.6613637207629243 [293] [123,257,144,200] -7 hSpCas9 negative selection 8795624
44216603 44216626 17 - 27260156 T47D viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.1320944529961527 [535] [630,519,495,639] -3 hSpCas9 negative selection 8852628
44216690 44216713 17 - 27260156 T47D viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.19978642966132798 [293] [316,237,330,311] -4 hSpCas9 negative selection 8916875
44216603 44216626 17 - 27260156 SU8686 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.8602059592060844 [535] [262,357,275,260] -8 hSpCas9 negative selection 8973879
44216690 44216713 17 - 27260156 SU8686 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.6594151718453479 [293] [170,210,126,231] -7 hSpCas9 negative selection 9038126
44216603 44216626 17 - 27260156 SKES1 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.19828154733808348 [535] [679,387,346,465] -4 hSpCas9 negative selection 9095130
44216690 44216713 17 - 27260156 SKES1 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.24491968787572205 [293] [277,342,192,195] -5 hSpCas9 negative selection 9159377
44216603 44216626 17 - 27260156 TOV112D viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.49628246149690636 [535] [290,451,309,475] -7 hSpCas9 negative selection 9216381
44216690 44216713 17 - 27260156 TOV112D viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.08059655053405101 [293] [125,368,464,165] -1 hSpCas9 negative selection 9280628
44216603 44216626 17 - 27260156 TC71 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.34747680298499306 [535] [439,385,566,406] -7 hSpCas9 negative selection 9337632
44216690 44216713 17 - 27260156 TC71 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.3753452832164387 [293] [237,278,201,254] -8 hSpCas9 negative selection 9401879
44216603 44216626 17 - 27260156 TC32 viability CAAAACCACCGAATCACACATGG UBTF ENSG00000108312 -0.4522159754142019 [535] [345,221,500,469] -7 hSpCas9 negative selection 9458883
44216690 44216713 17 - 27260156 TC32 viability TTTACCAGACCGTTGGTCCCAGG UBTF ENSG00000108312 -0.28114578487131603 [293] [245,133,251,305] -5 hSpCas9 negative selection 9523130