Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 64601
• Symbol: VPS16
• Description: VPS16 core subunit of CORVET and HOPS complexes

DataSource: http://genomecrispr.dkfz.de/#!/results/VPS16

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
2860235	2860258	20	+	26472758	Jiyoye	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.09422240257615147	[108]	[76]	0	hSpCas9	negative selection	179982
2859737	2859760	20	+	26472758	Jiyoye	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.2241800246997339	[157]	[50]	-7	hSpCas9	negative selection	179983
2859758	2859781	20	+	26472758	Jiyoye	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-1.4293258862112475	[24]	[6]	-7	hSpCas9	negative selection	179985
2860101	2860124	20	-	26472758	Jiyoye	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.8625227546089312	[216]	[89]	-6	hSpCas9	negative selection	179986
2861660	2861683	20	+	26472758	Jiyoye	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.7907639961060356	[77]	[33]	-5	hSpCas9	negative selection	179987
2863986	2864009	20	+	26472758	Jiyoye	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-1.1023797165572602	[204]	[71]	-6	hSpCas9	negative selection	179988
2860235	2860258	20	+	26472758	KBM7	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.2439381041714388	[416,269]	[56,75]	-7	hSpCas9	negative selection	371100
2859737	2859760	20	+	26472758	KBM7	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.8818241063424195	[492,452]	[90,32]	-8	hSpCas9	negative selection	371101
2859758	2859781	20	+	26472758	KBM7	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.4598177582934904	[213,90]	[1,21]	-9	hSpCas9	negative selection	371103
2860101	2860124	20	-	26472758	KBM7	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.129498381867509	[657,416]	[80,34]	-8	hSpCas9	negative selection	371104
2861660	2861683	20	+	26472758	KBM7	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	1.086182728988737	[87,55]	[49,88]	9	hSpCas9	negative selection	371105
2863986	2864009	20	+	26472758	KBM7	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.796852137771385	[323,420]	[80,121]	-6	hSpCas9	negative selection	371106
2860235	2860258	20	+	26472758	Raji	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.5822763440142501	[199]	[30]	-4	hSpCas9	negative selection	562218
2859737	2859760	20	+	26472758	Raji	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.6150824890974917	[197]	[14]	-8	hSpCas9	negative selection	562219
2859758	2859781	20	+	26472758	Raji	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-3.846812775013276	[61]	[0]	-9	hSpCas9	negative selection	562221
2860101	2860124	20	-	26472758	Raji	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.8600486021699698	[218]	[13]	-8	hSpCas9	negative selection	562222
2861660	2861683	20	+	26472758	Raji	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	0.37041794120739313	[29]	[8]	3	hSpCas9	negative selection	562223
2863986	2864009	20	+	26472758	Raji	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.9321448288130378	[221]	[26]	-6	hSpCas9	negative selection	562224
2860235	2860258	20	+	26472758	K562	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.622943503755434	[269]	[73]	-7	hSpCas9	negative selection	753336
2859737	2859760	20	+	26472758	K562	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.7336886664847109	[326]	[82]	-7	hSpCas9	negative selection	753337
2859758	2859781	20	+	26472758	K562	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-6.355494114520679	[96]	[0]	-9	hSpCas9	negative selection	753339
2860101	2860124	20	-	26472758	K562	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.9057430189544357	[434]	[195]	-5	hSpCas9	negative selection	753340
2861660	2861683	20	+	26472758	K562	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-1.1706187716123968	[71]	[26]	-6	hSpCas9	negative selection	753341
2863986	2864009	20	+	26472758	K562	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.26954300415357024	[336]	[235]	-2	hSpCas9	negative selection	753342
2859724	2859747	20	+	26627737	DLD1	viability	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.18910811167147512	[386]	[41,118,150]	-2	hSpCas9	negative selection	813798
2860101	2860124	20	-	26627737	DLD1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.9556208683001293	[396]	[58,38,88]	-7	hSpCas9	negative selection	813799
2860340	2860363	20	+	26627737	DLD1	viability	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.471486505780063	[991]	[265,260,155]	-5	hSpCas9	negative selection	813800
2860504	2860527	20	+	26627737	DLD1	viability	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.10443190482025133	[1313]	[423,394,334]	-1	hSpCas9	negative selection	813801
2861020	2861043	20	+	26627737	DLD1	viability	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.05346662336637675	[1008]	[245,413,325]	0	hSpCas9	negative selection	813802
2859724	2859747	20	+	26627737	GBM cells	viability after 5 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	0.4321328005128434	[122]	[80,96]	6	hSpCas9	negative selection	896113
2860101	2860124	20	-	26627737	GBM cells	viability after 5 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.7649040465467102	[140]	[54,33]	-8	hSpCas9	negative selection	896114
2860340	2860363	20	+	26627737	GBM cells	viability after 5 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.10702207021588606	[463]	[273,261]	1	hSpCas9	negative selection	896115
2860504	2860527	20	+	26627737	GBM cells	viability after 5 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.5135603998566898	[464]	[330,380]	7	hSpCas9	negative selection	896116
2861020	2861043	20	+	26627737	GBM cells	viability after 5 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.14753783779531315	[435]	[269,247]	2	hSpCas9	negative selection	896117
2859724	2859747	20	+	26627737	GBM cells	viability after 13 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	0.17391297680888973	[122]	[98,55]	2	hSpCas9	negative selection	978428
2860101	2860124	20	-	26627737	GBM cells	viability after 13 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.0411303218935823	[140]	[22,14]	-9	hSpCas9	negative selection	978429
2860340	2860363	20	+	26627737	GBM cells	viability after 13 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.6295744112059941	[463]	[410,371]	7	hSpCas9	negative selection	978430
2860504	2860527	20	+	26627737	GBM cells	viability after 13 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.3960236966129802	[464]	[315,344]	5	hSpCas9	negative selection	978431
2861020	2861043	20	+	26627737	GBM cells	viability after 13 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.41302578458671435	[435]	[341,292]	5	hSpCas9	negative selection	978432
2859724	2859747	20	+	26627737	GBM cells	viability after 21 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.5049664296810865	[122]	[44,48]	-4	hSpCas9	negative selection	1060743
2860101	2860124	20	-	26627737	GBM cells	viability after 21 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.22858961785798	[140]	[19,12]	-9	hSpCas9	negative selection	1060744
2860340	2860363	20	+	26627737	GBM cells	viability after 21 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.035342303928529994	[463]	[273,243]	0	hSpCas9	negative selection	1060745
2860504	2860527	20	+	26627737	GBM cells	viability after 21 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.682941666182785	[464]	[403,406]	7	hSpCas9	negative selection	1060746
2861020	2861043	20	+	26627737	GBM cells	viability after 21 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.7532176471821771	[435]	[404,393]	7	hSpCas9	negative selection	1060747
2859724	2859747	20	+	26627737	RPE1	viability after 9 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.8954785771084107	[568]	[131,48]	-6	hSpCas9	negative selection	1143058
2860101	2860124	20	-	26627737	RPE1	viability after 9 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.4203329056376297	[973]	[140,78]	-7	hSpCas9	negative selection	1143059
2860340	2860363	20	+	26627737	RPE1	viability after 9 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	1.0879724087009521	[748]	[387,640]	6	hSpCas9	negative selection	1143060
2860504	2860527	20	+	26627737	RPE1	viability after 9 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.07398389946199524	[2988]	[974,777]	0	hSpCas9	negative selection	1143061
2861020	2861043	20	+	26627737	RPE1	viability after 9 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.8791410267884452	[1961]	[281,400]	-6	hSpCas9	negative selection	1143062
2859724	2859747	20	+	26627737	RPE1	viability after 12 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.8103899829997546	[568]	[75,98]	-5	hSpCas9	negative selection	1225373
2860101	2860124	20	-	26627737	RPE1	viability after 12 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.1313172393100333	[973]	[100,138]	-7	hSpCas9	negative selection	1225374
2860340	2860363	20	+	26627737	RPE1	viability after 12 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	1.2804743043602846	[748]	[397,584]	7	hSpCas9	negative selection	1225375
2860504	2860527	20	+	26627737	RPE1	viability after 12 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.02440979484839989	[2988]	[927,642]	0	hSpCas9	negative selection	1225376
2861020	2861043	20	+	26627737	RPE1	viability after 12 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.8202036731831883	[1961]	[197,404]	-5	hSpCas9	negative selection	1225377
2859724	2859747	20	+	26627737	RPE1	viability after 15 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-1.5794615193824186	[568]	[89,18]	-7	hSpCas9	negative selection	1307688
2860101	2860124	20	-	26627737	RPE1	viability after 15 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.1166763324099562	[973]	[179,75]	-6	hSpCas9	negative selection	1307689
2860340	2860363	20	+	26627737	RPE1	viability after 15 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	1.038421211009981	[748]	[508,363]	6	hSpCas9	negative selection	1307690
2860504	2860527	20	+	26627737	RPE1	viability after 15 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.2612006617449576	[2988]	[1014,406]	-2	hSpCas9	negative selection	1307691
2861020	2861043	20	+	26627737	RPE1	viability after 15 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.49195780678350365	[1961]	[470,320]	-3	hSpCas9	negative selection	1307692
2859724	2859747	20	+	26627737	RPE1	viability after 18 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-1.829055860779977	[568]	[34,51]	-8	hSpCas9	negative selection	1390003
2860101	2860124	20	-	26627737	RPE1	viability after 18 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.8858128431745251	[973]	[134,149]	-5	hSpCas9	negative selection	1390004
2860340	2860363	20	+	26627737	RPE1	viability after 18 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.41007020253381443	[748]	[270,265]	2	hSpCas9	negative selection	1390005
2860504	2860527	20	+	26627737	RPE1	viability after 18 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.28842110679831046	[2988]	[717,598]	-2	hSpCas9	negative selection	1390006
2861020	2861043	20	+	26627737	RPE1	viability after 18 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.4834337669521863	[1961]	[326,433]	-3	hSpCas9	negative selection	1390007
2859724	2859747	20	+	26627737	HeLa	viability after 8 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	3.8661568592795574	[35]	[116,303,238]	9	hSpCas9	negative selection	1472318
2860101	2860124	20	-	26627737	HeLa	viability after 8 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.524967948146786	[595]	[8,39,75]	-9	hSpCas9	negative selection	1472319
2860340	2860363	20	+	26627737	HeLa	viability after 8 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.9708679038838333	[1030]	[112,316,230]	-7	hSpCas9	negative selection	1472320
2860504	2860527	20	+	26627737	HeLa	viability after 8 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.7207142339819507	[702]	[620,470,449]	6	hSpCas9	negative selection	1472321
2861020	2861043	20	+	26627737	HeLa	viability after 8 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.5989128187346184	[968]	[219,170,420]	-5	hSpCas9	negative selection	1472322
2859724	2859747	20	+	26627737	HeLa	viability after 12 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	3.1456731151475155	[35]	[3,190,189]	9	hSpCas9	negative selection	1554633
2860101	2860124	20	-	26627737	HeLa	viability after 12 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.4495392227130406	[595]	[66,2,0]	-9	hSpCas9	negative selection	1554634
2860340	2860363	20	+	26627737	HeLa	viability after 12 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.35938956082498974	[1030]	[303,242,457]	-3	hSpCas9	negative selection	1554635
2860504	2860527	20	+	26627737	HeLa	viability after 12 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.068754600510354	[702]	[518,869,408]	7	hSpCas9	negative selection	1554636
2861020	2861043	20	+	26627737	HeLa	viability after 12 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.4344282612469881	[968]	[262,305,317]	-4	hSpCas9	negative selection	1554637
2859724	2859747	20	+	26627737	HeLa	viability after 15 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	3.0762071551979413	[35]	[51,35,296]	9	hSpCas9	negative selection	1636948
2860101	2860124	20	-	26627737	HeLa	viability after 15 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.6921197331777789	[595]	[64,77,82]	-9	hSpCas9	negative selection	1636949
2860340	2860363	20	+	26627737	HeLa	viability after 15 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.427034176040901	[1030]	[346,241,349]	-4	hSpCas9	negative selection	1636950
2860504	2860527	20	+	26627737	HeLa	viability after 15 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.0067811388129582	[702]	[398,795,528]	7	hSpCas9	negative selection	1636951
2861020	2861043	20	+	26627737	HeLa	viability after 15 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.2779194940287433	[968]	[275,371,328]	-2	hSpCas9	negative selection	1636952
2859724	2859747	20	+	26627737	HeLa	viability after 18 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	3.0657438021581878	[35]	[32,29,296]	9	hSpCas9	negative selection	1719263
2860101	2860124	20	-	26627737	HeLa	viability after 18 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.7008550819689552	[595]	[43,62,82]	-9	hSpCas9	negative selection	1719264
2860340	2860363	20	+	26627737	HeLa	viability after 18 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.4349709964558821	[1030]	[228,200,349]	-4	hSpCas9	negative selection	1719265
2860504	2860527	20	+	26627737	HeLa	viability after 18 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.9990185268705215	[702]	[256,664,528]	7	hSpCas9	negative selection	1719266
2861020	2861043	20	+	26627737	HeLa	viability after 18 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.24503240610159338	[968]	[198,308,328]	-2	hSpCas9	negative selection	1719267
2859724	2859747	20	+	26627737	HCT116	viability after 6 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	2.474575331691793	[540]	[94,680]	9	hSpCas9	negative selection	1801578
2860101	2860124	20	-	26627737	HCT116	viability after 6 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.8258028978056964	[1030]	[124,1]	-8	hSpCas9	negative selection	1801579
2860340	2860363	20	+	26627737	HCT116	viability after 6 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.7431791534762898	[970]	[114,332]	4	hSpCas9	negative selection	1801580
2860504	2860527	20	+	26627737	HCT116	viability after 6 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.6721310960383253	[1172]	[492,183]	4	hSpCas9	negative selection	1801581
2861020	2861043	20	+	26627737	HCT116	viability after 6 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.2674023522212796	[738]	[66,179]	1	hSpCas9	negative selection	1801582
2859724	2859747	20	+	26627737	HCT116	viability after 8 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	0.43320351380915123	[230]	[125,69,316]	4	hSpCas9	negative selection	1883893
2860101	2860124	20	-	26627737	HCT116	viability after 8 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	0.6979469690329098	[135]	[126,132,104]	6	hSpCas9	negative selection	1883894
2860340	2860363	20	+	26627737	HCT116	viability after 8 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.22185432398715765	[564]	[248,239,310]	-3	hSpCas9	negative selection	1883895
2860504	2860527	20	+	26627737	HCT116	viability after 8 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.22394100738177203	[729]	[545,250,611]	2	hSpCas9	negative selection	1883896
2861020	2861043	20	+	26627737	HCT116	viability after 8 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.309912071815441	[554]	[341,168,230]	-4	hSpCas9	negative selection	1883897
2859724	2859747	20	+	26627737	HCT116	viability after 9 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.3635470743656397	[540]	[142,87]	-3	hSpCas9	negative selection	1966208
2860101	2860124	20	-	26627737	HCT116	viability after 9 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.061035591862436	[1030]	[70,61]	-8	hSpCas9	negative selection	1966209
2860340	2860363	20	+	26627737	HCT116	viability after 9 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	1.1420334704574495	[970]	[493,633]	7	hSpCas9	negative selection	1966210
2860504	2860527	20	+	26627737	HCT116	viability after 9 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.5700335160754562	[1172]	[488,445]	4	hSpCas9	negative selection	1966211
2861020	2861043	20	+	26627737	HCT116	viability after 9 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	1.3651647152313893	[738]	[385,604]	8	hSpCas9	negative selection	1966212
2859724	2859747	20	+	26627737	HCT116	viability after 12 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.2487091568433175	[230]	[84,100,121]	-3	hSpCas9	negative selection	2048523
2860101	2860124	20	-	26627737	HCT116	viability after 12 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	0.5329892843211863	[135]	[139,60,104]	5	hSpCas9	negative selection	2048524
2860340	2860363	20	+	26627737	HCT116	viability after 12 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.4399042676431036	[564]	[142,287,233]	-5	hSpCas9	negative selection	2048525
2860504	2860527	20	+	26627737	HCT116	viability after 12 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	-0.03850920720734052	[729]	[349,263,505]	0	hSpCas9	negative selection	2048526
2861020	2861043	20	+	26627737	HCT116	viability after 12 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.18915974616262088	[554]	[322,231,205]	-2	hSpCas9	negative selection	2048527
2859724	2859747	20	+	26627737	HCT116	viability after 15 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.05524212113409965	[230]	[163,57,164]	0	hSpCas9	negative selection	2130838
2860101	2860124	20	-	26627737	HCT116	viability after 15 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	0.3141932058709964	[135]	[125,84,83]	3	hSpCas9	negative selection	2130839
2860340	2860363	20	+	26627737	HCT116	viability after 15 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.24799782453162122	[564]	[297,275,248]	-3	hSpCas9	negative selection	2130840
2860504	2860527	20	+	26627737	HCT116	viability after 15 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.1330073667990186	[729]	[483,344,551]	1	hSpCas9	negative selection	2130841
2861020	2861043	20	+	26627737	HCT116	viability after 15 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.04769571854535182	[554]	[370,358,203]	0	hSpCas9	negative selection	2130842
2859724	2859747	20	+	26627737	HCT116	viability after 18 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.23078089878111385	[230]	[89,15,188]	-2	hSpCas9	negative selection	2213153
2860101	2860124	20	-	26627737	HCT116	viability after 18 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	0.6748594008268238	[135]	[155,65,94]	5	hSpCas9	negative selection	2213154
2860340	2860363	20	+	26627737	HCT116	viability after 18 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.6450983127984431	[564]	[134,267,111]	-5	hSpCas9	negative selection	2213155
2860504	2860527	20	+	26627737	HCT116	viability after 18 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.28723055703745626	[729]	[428,242,641]	2	hSpCas9	negative selection	2213156
2861020	2861043	20	+	26627737	HCT116	viability after 18 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.6910361593230427	[554]	[233,151,110]	-6	hSpCas9	negative selection	2213157
2841346	2841369	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATCTGGGTAACGATGTAACGGG	VPS16	ENSG00000215305	0.09963580437701491	[361,90]	[93,7]	0	dCas9-VP64	positive selection	2418145
2841396	2841419	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAAAACTACGAACTTCTCGTGG	VPS16	ENSG00000215305	-0.13434850250587949	[50,76]	[5,18]	0	dCas9-VP64	positive selection	2418146
2841316	2841339	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTAGAAAAATCCGTGGTTTAGG	VPS16	ENSG00000215305	0.8217587204341525	[498,66]	[193,16]	3	dCas9-VP64	positive selection	2418147
2864015	2864038	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGTCGGAGTAAGAGACACCAGG	VPS16	ENSG00000215305	1.6716107106910867	[125,25]	[74,27]	6	dCas9-VP64	positive selection	2431518
2864076	2864099	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGGGCACCCACACCTTGATGG	VPS16	ENSG00000215305	0.5737926063395682	[83,40]	[29,8]	2	dCas9-VP64	positive selection	2431519
2864053	2864076	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGTTGTGGCCGCACGGAGCTGG	VPS16	ENSG00000215305	1.4959313214685022	[2,9]	[0,5]	5	dCas9-VP64	positive selection	2431520
2841346	2841369	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATCTGGGTAACGATGTAACGGG	VPS16	ENSG00000215305	-0.009376918828899683	[285,46]	[64,43]	0	dCas9-VP64	positive selection	2513400
2841396	2841419	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAAAACTACGAACTTCTCGTGG	VPS16	ENSG00000215305	4.357510683636807	[80,155]	[63,1473]	9	dCas9-VP64	positive selection	2513401
2841316	2841339	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTAGAAAAATCCGTGGTTTAGG	VPS16	ENSG00000215305	-0.28087191270919937	[124,156]	[29,43]	-3	dCas9-VP64	positive selection	2513402
2864015	2864038	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGTCGGAGTAAGAGACACCAGG	VPS16	ENSG00000215305	1.671743833628	[475,289]	[43,733]	8	dCas9-VP64	positive selection	2526773
2864076	2864099	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGGGCACCCACACCTTGATGG	VPS16	ENSG00000215305	0.6009630767432647	[185,225]	[46,152]	4	dCas9-VP64	positive selection	2526774
2864053	2864076	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGTTGTGGCCGCACGGAGCTGG	VPS16	ENSG00000215305	-0.22643413685023062	[57,57]	[23,7]	-2	dCas9-VP64	positive selection	2526775
2861625	2861648	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	-0.4040463356128978	[3,2]	[2,0]	-5	hSpCas9	positive selection	3031890
2861644	2861667	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	-0.32591423867380503	[3,3]	[1,2]	-4	hSpCas9	positive selection	3031891
2860068	2860091	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	-0.4291058544648101	[4,4]	[3,1]	-6	hSpCas9	positive selection	3031892
2860236	2860259	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.32089717448718125	[2,3]	[2,0]	-4	hSpCas9	positive selection	3031893
2861625	2861648	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	-0.3855912578072252	[3,3]	[1,1]	-5	hSpCas9	positive selection	3099748
2861644	2861667	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	-0.38508666964431326	[3,3]	[3,0]	-5	hSpCas9	positive selection	3099749
2860068	2860091	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	0.22450663120494396	[4,4]	[4,2]	4	hSpCas9	positive selection	3099750
2860236	2860259	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.463494534007061	[2,2]	[2,0]	-6	hSpCas9	positive selection	3099751
2859790	2859813		-	24336571	A375	resistance to PLX after 7 days	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.1489921094098991	[16,14]	[17,15]	5	hSpCas9	positive selection	3155071
2859745	2859768		+	24336571	A375	resistance to PLX after 7 days	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.5170073621809024	[5,5]	[7,9]	9	hSpCas9	positive selection	3155072
2860503	2860526		+	24336571	A375	resistance to PLX after 7 days	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.10615422274517172	[64,61]	[68,66]	3	hSpCas9	positive selection	3155073
2859790	2859813		-	24336571	A375	resistance to PLX after 14 days	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.163142707750943	[11,16]	[5,4]	-2	hSpCas9	positive selection	3212864
2859745	2859768		+	24336571	A375	resistance to PLX after 14 days	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.3783466066515966	[4,5]	[2,2]	3	hSpCas9	positive selection	3212865
2860503	2860526		+	24336571	A375	resistance to PLX after 14 days	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3807701620758315	[58,64]	[39,34]	3	hSpCas9	positive selection	3212866
2859790	2859813		-	24336571	A375	viability after 7 days	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.4817856812568367	[22]	[16,14]	-6	hSpCas9	negative selection	3270657
2859745	2859768		+	24336571	A375	viability after 7 days	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.6988511676360445	[10]	[5,5]	-7	hSpCas9	negative selection	3270658
2860503	2860526		+	24336571	A375	viability after 7 days	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.6148971216897587	[42]	[64,61]	8	hSpCas9	negative selection	3270659
2859790	2859813		-	24336571	A375	viability after 14 days	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.5394011622605589	[22]	[11,16]	-6	hSpCas9	negative selection	3328450
2859745	2859768		+	24336571	A375	viability after 14 days	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.7905162476424987	[10]	[4,5]	-7	hSpCas9	negative selection	3328451
2860503	2860526		+	24336571	A375	viability after 14 days	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5981671203862233	[42]	[58,64]	7	hSpCas9	negative selection	3328452
2860478	2860501	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.6851882938934047	[245,245]	[0,0]	-5	hSpCas9	positive selection	3400975
2860827	2860850	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-1.5403353144079248	[444,444]	[0,0]	-8	hSpCas9	positive selection	3400976
2859745	2859768	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.7337642553888224	[91,91]	[0,0]	3	hSpCas9	positive selection	3400977
2861625	2861648	20	-	26780180	HT29	viability (Avana library 4 designs)	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	4.01982161754391	[]	[]	9	hSpCas9	negative selection	3471122
2861644	2861667	20	-	26780180	HT29	viability (Avana library 4 designs)	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	3.01251238789011	[]	[]	8	hSpCas9	negative selection	3471123
2860068	2860091	20	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	1.10051760374673	[]	[]	4	hSpCas9	negative selection	3471124
2860235	2860258	20	+	26780180	HT29	viability (Avana library 4 designs)	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	4.80333957347089	[]	[]	9	hSpCas9	negative selection	3471125
2860068	2860091	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	2.19528915092574	[]	[]	3	hSpCas9	negative selection	3577772
2861625	2861648	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	-6.59254575305998	[]	[]	-6	hSpCas9	negative selection	3577773
2860235	2860258	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-3.58867444083446	[]	[]	-4	hSpCas9	negative selection	3577774
2861644	2861667	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	4.15604506251774	[]	[]	6	hSpCas9	negative selection	3577775
2860975	2860998	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTCCTGGGGCCAGGCCAGGG	VPS16	ENSG00000215305	6.03318911799819	[]	[]	9	hSpCas9	negative selection	3577776
2860068	2860091	20	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	-0.478668646955013	[]	[]	0	hSpCas9	negative selection	3686431
2861625	2861648	20	-	26780180	A375	viability (Avana lentiGuide)	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	10.2701930336583	[]	[]	7	hSpCas9	negative selection	3686432
2860235	2860258	20	+	26780180	A375	viability (Avana lentiGuide)	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	13.7327158555723	[]	[]	7	hSpCas9	negative selection	3686433
2861644	2861667	20	-	26780180	A375	viability (Avana lentiGuide)	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	4.38186134907476	[]	[]	4	hSpCas9	negative selection	3686434
2860975	2860998	20	-	26780180	A375	viability (Avana lentiGuide)	TTACTCCTGGGGCCAGGCCAGGG	VPS16	ENSG00000215305	-0.317628329254951	[]	[]	0	hSpCas9	negative selection	3686435
2860068	2860091	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	0.10930182767327645	[5]	[6,5]	3	hSpCas9	positive selection	3795038
2861625	2861648	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	-0.29107468566760136	[4]	[4,1]	-4	hSpCas9	positive selection	3795039
2860235	2860258	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	0.025331604422666902	[4]	[5,4]	0	hSpCas9	positive selection	3795040
2861644	2861667	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	0.20535611479927895	[4]	[5,3]	6	hSpCas9	positive selection	3795041
2860975	2860998	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTCCTGGGGCCAGGCCAGGG	VPS16	ENSG00000215305	0.37652956023462303	[5]	[7,7]	9	hSpCas9	positive selection	3795042
2860068	2860091	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTTTCTCCTTCCGCCAGGG	VPS16	ENSG00000215305	0.14031903374913784	[6]	[5,6]	3	hSpCas9	positive selection	3903645
2861625	2861648	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGGCCCTCTCCTTGCTACGAGG	VPS16	ENSG00000215305	-0.9971758958983412	[5]	[1,1]	-8	hSpCas9	positive selection	3903646
2860235	2860258	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.6098213311505348	[5]	[1,3]	-7	hSpCas9	positive selection	3903647
2861644	2861667	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTTCCCAGGCCACCACCACGG	VPS16	ENSG00000215305	-0.24846319600451455	[5]	[3,4]	-3	hSpCas9	positive selection	3903648
2860975	2860998	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTCCTGGGGCCAGGCCAGGG	VPS16	ENSG00000215305	0.18811583810884377	[5]	[5,5]	4	hSpCas9	positive selection	3903649
2860478	2860501	20	-	26780180	A375	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	2.37364941836508	[]	[]	9	hSpCas9	negative selection	4011710
2859790	2859813	20	-	26780180	A375	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	1.07750956253965	[]	[]	5	hSpCas9	negative selection	4011711
2860827	2860850	20	-	26780180	A375	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.801873394092168	[]	[]	3	hSpCas9	negative selection	4011712
2860850	2860873	20	-	26780180	A375	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.82849572620808	[]	[]	3	hSpCas9	negative selection	4011713
2859745	2859768	20	+	26780180	A375	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	1.29137168958819	[]	[]	7	hSpCas9	negative selection	4011714
2860503	2860526	20	+	26780180	A375	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	2.01585506490098	[]	[]	9	hSpCas9	negative selection	4011715
2860478	2860501	20	-	26780180	HT29	viability (GeCKOv2 library)	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	2.40226764757822	[]	[]	9	hSpCas9	negative selection	4119676
2859790	2859813	20	-	26780180	HT29	viability (GeCKOv2 library)	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	1.19983190026764	[]	[]	6	hSpCas9	negative selection	4119677
2860827	2860850	20	-	26780180	HT29	viability (GeCKOv2 library)	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.564563159046948	[]	[]	2	hSpCas9	negative selection	4119678
2860850	2860873	20	-	26780180	HT29	viability (GeCKOv2 library)	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	1.53119127351405	[]	[]	7	hSpCas9	negative selection	4119679
2859745	2859768	20	+	26780180	HT29	viability (GeCKOv2 library)	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	1.46050990411236	[]	[]	7	hSpCas9	negative selection	4119680
2860503	2860526	20	+	26780180	HT29	viability (GeCKOv2 library)	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	2.26324039735813	[]	[]	9	hSpCas9	negative selection	4119681
2859790	2859813	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.07249105108540677	[4]	[3,2]	1	hSpCas9	positive selection	4181823
2859745	2859768	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.46952471684371544	[3]	[0,1]	-8	hSpCas9	positive selection	4181824
2860503	2860526	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.25685955436878105	[5]	[4,5]	6	hSpCas9	positive selection	4181825
2859790	2859813	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.34176352105024627	[4]	[0,0,4,0]	-5	hSpCas9	positive selection	4245845
2859745	2859768	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.3827445101970066	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4245846
2860503	2860526	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.8761960315327204	[5]	[4,4,5,3]	6	hSpCas9	positive selection	4245847
2860503	2860526	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.012803537721141733	[4]	[3,2]	0	hSpCas9	positive selection	4307360
2859790	2859813	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.4923833016095185	[1]	[0,0]	-8	hSpCas9	positive selection	4307361
2860850	2860873	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.0611571306452231	[1]	[1,0]	1	hSpCas9	positive selection	4307362
2860478	2860501	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.40765163628114054	[3]	[2,1]	-7	hSpCas9	positive selection	4371608
2860827	2860850	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.5160247096539179	[3]	[3,3]	9	hSpCas9	positive selection	4371609
2859745	2859768	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.350236879074559	[1]	[1,0]	-6	hSpCas9	positive selection	4371610
2859790	2859812	20	-	27760321	OCIAML3	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.9248761763240105	[570,354]	[165,215]	-7	hSpCas9	negative selection	4453376
2860101	2860123	20	-	27760321	OCIAML3	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.626384020272323	[317,226]	[10,24]	-9	hSpCas9	negative selection	4453377
2860556	2860578	20	+	27760321	OCIAML3	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-0.5399519202355358	[398,407]	[164,286]	-5	hSpCas9	negative selection	4453378
2860849	2860871	20	+	27760321	OCIAML3	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-0.7270178412423691	[636,592]	[202,404]	-6	hSpCas9	negative selection	4453379
2861616	2861638	20	+	27760321	OCIAML3	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-1.1813410558597472	[912,711]	[200,378]	-8	hSpCas9	negative selection	4453380
2859790	2859812	20	-	27760321	OCIAML2	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.4611731092055188	[570,354]	[240,302]	-5	hSpCas9	negative selection	4536839
2860101	2860123	20	-	27760321	OCIAML2	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.7037685418211144	[317,226]	[50,87]	-9	hSpCas9	negative selection	4536840
2860556	2860578	20	+	27760321	OCIAML2	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-0.18590147012194555	[398,407]	[285,290]	-2	hSpCas9	negative selection	4536841
2860849	2860871	20	+	27760321	OCIAML2	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	0.29116977874678873	[636,592]	[548,687]	4	hSpCas9	negative selection	4536842
2861616	2861638	20	+	27760321	OCIAML2	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.2872421072307815	[912,711]	[483,601]	-4	hSpCas9	negative selection	4536843
2859790	2859812	20	-	27760321	MV411	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.9588693768676609	[570,354]	[23,350]	-6	hSpCas9	negative selection	4620302
2860101	2860123	20	-	27760321	MV411	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-7.475318840497513	[317,226]	[0,0]	-9	hSpCas9	negative selection	4620303
2860556	2860578	20	+	27760321	MV411	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	1.8236146971125635	[398,407]	[1507,102]	9	hSpCas9	negative selection	4620304
2860849	2860871	20	+	27760321	MV411	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-0.9738835395429333	[636,592]	[83,390]	-6	hSpCas9	negative selection	4620305
2861616	2861638	20	+	27760321	MV411	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.8368702270805195	[912,711]	[196,449]	-5	hSpCas9	negative selection	4620306
2859790	2859812	20	-	27760321	HL60	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-1.76942636227745	[570,354]	[81,137]	-9	hSpCas9	negative selection	4703765
2860101	2860123	20	-	27760321	HL60	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.1369202784415344	[317,226]	[55,146]	-8	hSpCas9	negative selection	4703766
2860556	2860578	20	+	27760321	HL60	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	0.5774482611921918	[398,407]	[374,619]	7	hSpCas9	negative selection	4703767
2860849	2860871	20	+	27760321	HL60	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-1.4545029658123143	[636,592]	[145,222]	-8	hSpCas9	negative selection	4703768
2861616	2861638	20	+	27760321	HL60	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.4650317121645502	[912,711]	[494,458]	-5	hSpCas9	negative selection	4703769
2859790	2859812	20	-	27760321	HT1080	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-4.1136349272228285	[354,276]	[12,0]	-8	hSpCas9	negative selection	4787228
2860101	2860123	20	-	27760321	HT1080	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-6.330311115215561	[226,176]	[0,0]	-9	hSpCas9	negative selection	4787229
2860556	2860578	20	+	27760321	HT1080	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-3.260579652772101	[407,318]	[27,0]	-7	hSpCas9	negative selection	4787230
2860849	2860871	20	+	27760321	HT1080	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-5.187161815465471	[592,462]	[0,10]	-8	hSpCas9	negative selection	4787231
2861616	2861638	20	+	27760321	HT1080	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-1.5443463090904386	[711,555]	[56,118]	-5	hSpCas9	negative selection	4787232
2859790	2859812	20	-	27760321	HT29	viability after 7 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.07804819907316377	[354,276]	[496,506,295]	1	hSpCas9	negative selection	4870691
2860101	2860123	20	-	27760321	HT29	viability after 7 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.1090142776319571	[226,176]	[212,128,34]	-8	hSpCas9	negative selection	4870692
2860556	2860578	20	+	27760321	HT29	viability after 7 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	0.04200649889002263	[407,318]	[515,516,416]	0	hSpCas9	negative selection	4870693
2860849	2860871	20	+	27760321	HT29	viability after 7 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	0.039918561094602234	[592,462]	[768,607,724]	0	hSpCas9	negative selection	4870694
2861616	2861638	20	+	27760321	HT29	viability after 7 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	0.6810322351652041	[711,555]	[1116,1471,1302]	9	hSpCas9	negative selection	4870695
2859790	2859812	20	-	27760321	HT29	viability after 25 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-4.497658649532028	[354,276]	[2,18,27]	-9	hSpCas9	negative selection	4954154
2860101	2860123	20	-	27760321	HT29	viability after 25 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-4.612713425391598	[226,176]	[15,9,0]	-9	hSpCas9	negative selection	4954155
2860556	2860578	20	+	27760321	HT29	viability after 25 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-1.492656043789728	[407,318]	[106,209,125]	-7	hSpCas9	negative selection	4954156
2860849	2860871	20	+	27760321	HT29	viability after 25 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-2.9544898292022896	[592,462]	[69,24,145]	-8	hSpCas9	negative selection	4954157
2861616	2861638	20	+	27760321	HT29	viability after 25 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.35432555645306213	[711,555]	[590,315,816]	-4	hSpCas9	negative selection	4954158
2859790	2859812	20	-	27760321	HT29	viability after 22 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-5.938142013496996	[354,276]	[1,7,7]	-9	hSpCas9	negative selection	5037617
2860101	2860123	20	-	27760321	HT29	viability after 22 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.103360020103888	[226,176]	[45,7,26]	-8	hSpCas9	negative selection	5037618
2860556	2860578	20	+	27760321	HT29	viability after 22 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-1.2755515448002588	[407,318]	[335,48,130]	-7	hSpCas9	negative selection	5037619
2860849	2860871	20	+	27760321	HT29	viability after 22 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-4.1926613350964415	[592,462]	[10,29,59]	-9	hSpCas9	negative selection	5037620
2861616	2861638	20	+	27760321	HT29	viability after 22 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.37046149679084933	[711,555]	[507,468,726]	-4	hSpCas9	negative selection	5037621
2859790	2859812	20	-	27760321	HT29	viability after 19 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-5.101070810196963	[354,276]	[10,19,0]	-9	hSpCas9	negative selection	5121080
2860101	2860123	20	-	27760321	HT29	viability after 19 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-4.830680731486971	[226,176]	[21,0,2]	-9	hSpCas9	negative selection	5121081
2860556	2860578	20	+	27760321	HT29	viability after 19 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-0.7245508376767799	[407,318]	[299,321,141]	-5	hSpCas9	negative selection	5121082
2860849	2860871	20	+	27760321	HT29	viability after 19 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-3.758134064876729	[592,462]	[69,7,57]	-9	hSpCas9	negative selection	5121083
2861616	2861638	20	+	27760321	HT29	viability after 19 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.5194764300654937	[711,555]	[614,416,496]	-4	hSpCas9	negative selection	5121084
2859790	2859812	20	-	27760321	HT29	viability after 16 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-5.1366963168632696	[354,276]	[5,0,22]	-9	hSpCas9	negative selection	5204543
2860101	2860123	20	-	27760321	HT29	viability after 16 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-5.039959276403378	[226,176]	[19,0,0]	-9	hSpCas9	negative selection	5204544
2860556	2860578	20	+	27760321	HT29	viability after 16 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-1.5347301379229124	[407,318]	[234,65,130]	-8	hSpCas9	negative selection	5204545
2860849	2860871	20	+	27760321	HT29	viability after 16 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-3.6500658651791964	[592,462]	[10,75,49]	-9	hSpCas9	negative selection	5204546
2861616	2861638	20	+	27760321	HT29	viability after 16 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.14049674997478978	[711,555]	[560,630,730]	-1	hSpCas9	negative selection	5204547
2859790	2859812	20	-	27760321	HT29	viability after 13 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-3.388853286121888	[354,276]	[3,30,67]	-9	hSpCas9	negative selection	5288006
2860101	2860123	20	-	27760321	HT29	viability after 13 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.310523870904005	[226,176]	[29,19,20]	-9	hSpCas9	negative selection	5288007
2860556	2860578	20	+	27760321	HT29	viability after 13 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-1.64982581273287	[407,318]	[137,178,88]	-8	hSpCas9	negative selection	5288008
2860849	2860871	20	+	27760321	HT29	viability after 13 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-2.2187291770431177	[592,462]	[46,182,162]	-9	hSpCas9	negative selection	5288009
2861616	2861638	20	+	27760321	HT29	viability after 13 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.5061104850979139	[711,555]	[362,434,741]	-5	hSpCas9	negative selection	5288010
2859790	2859812	20	-	27760321	HT29	viability after 10 days	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.9151782087132443	[354,276]	[208,156,258]	-7	hSpCas9	negative selection	5371469
2860101	2860123	20	-	27760321	HT29	viability after 10 days	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.6686409350695126	[226,176]	[58,68,108]	-8	hSpCas9	negative selection	5371470
2860556	2860578	20	+	27760321	HT29	viability after 10 days	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-0.5394798039528726	[407,318]	[183,272,474]	-6	hSpCas9	negative selection	5371471
2860849	2860871	20	+	27760321	HT29	viability after 10 days	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-0.9872181994300058	[592,462]	[136,627,242]	-8	hSpCas9	negative selection	5371472
2861616	2861638	20	+	27760321	HT29	viability after 10 days	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-5.4914577209186355e-05	[711,555]	[814,848,713]	0	hSpCas9	negative selection	5371473
2859790	2859812	20	-	27760321	MOLM13	viability	ATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-1.5072418964134011	[570,354]	[171,20]	-7	hSpCas9	negative selection	5454932
2860101	2860123	20	-	27760321	MOLM13	viability	CAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.8594989645254492	[317,226]	[89,0]	-7	hSpCas9	negative selection	5454933
2860556	2860578	20	+	27760321	MOLM13	viability	GGGTGACCTCAAACTCCGCCGG	VPS16	ENSG00000215305	-0.2187774705922992	[398,407]	[324,86]	-1	hSpCas9	negative selection	5454934
2860849	2860871	20	+	27760321	MOLM13	viability	GCCTGCTCCGCAGTGGTAAGGG	VPS16	ENSG00000215305	-0.685595767463157	[636,592]	[251,184]	-4	hSpCas9	negative selection	5454935
2861616	2861638	20	+	27760321	MOLM13	viability	TGCAGCCGTCCTCGTAGCAAGG	VPS16	ENSG00000215305	-0.7901825791829954	[912,711]	[252,271]	-5	hSpCas9	negative selection	5454936
2860503	2860526	20	+	27260156	BXPC3	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5073419916581732	[993]	[1314,1594,1383,1632]	9	hSpCas9	negative selection	5579820
2859790	2859813	20	-	27260156	BXPC3	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.0030330645224330155	[105]	[120,153,99,57]	0	hSpCas9	negative selection	5579821
2860850	2860873	20	-	27260156	BXPC3	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.09811154386201637	[110]	[62,142,167,128]	2	hSpCas9	negative selection	5579822
2860478	2860501	20	-	27260156	BXPC3	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5401046200261952	[850]	[457,591,776,640]	-8	hSpCas9	negative selection	5644068
2860827	2860850	20	-	27260156	BXPC3	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.32289863463525165	[644]	[703,822,900,973]	7	hSpCas9	negative selection	5644069
2859745	2859768	20	+	27260156	BXPC3	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.1657155455275905	[184]	[208,126,189,159]	-4	hSpCas9	negative selection	5644070
2860503	2860526	20	+	27260156	A673	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.2557461771233598	[993]	[1533,1291,1343,1550]	6	hSpCas9	negative selection	5701071
2859790	2859813	20	-	27260156	A673	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.11052936864852292	[105]	[104,89,101,176]	-3	hSpCas9	negative selection	5701072
2860850	2860873	20	-	27260156	A673	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.27771588949424975	[110]	[245,92,164,152]	6	hSpCas9	negative selection	5701073
2860478	2860501	20	-	27260156	A673	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.409550776617605	[850]	[915,773,701,696]	-7	hSpCas9	negative selection	5765319
2860827	2860850	20	-	27260156	A673	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.6818919651057205	[644]	[1383,1234,1179,1181]	9	hSpCas9	negative selection	5765320
2859745	2859768	20	+	27260156	A673	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.1570151114766063	[184]	[230,186,221,157]	-4	hSpCas9	negative selection	5765321
2860503	2860526	20	+	27260156	A375	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3528125743284145	[993]	[1482,1837,1427,1252]	5	hSpCas9	negative selection	5822322
2859790	2859813	20	-	27260156	A375	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.4946423999621805	[105]	[118,58,68,98]	-6	hSpCas9	negative selection	5822323
2860850	2860873	20	-	27260156	A375	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.6050807130506621	[110]	[22,59,143,106]	-7	hSpCas9	negative selection	5822324
2860478	2860501	20	-	27260156	A375	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.7415690044556545	[850]	[510,684,748,458]	-7	hSpCas9	negative selection	5886570
2860827	2860850	20	-	27260156	A375	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.40931216443912233	[644]	[742,530,374,608]	-5	hSpCas9	negative selection	5886571
2859745	2859768	20	+	27260156	A375	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.5354321492677039	[184]	[257,88,154,92]	-6	hSpCas9	negative selection	5886572
2860503	2860526	20	+	27260156	COLO741	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.6382574768233524	[993]	[2049,2087,1806]	9	hSpCas9	negative selection	5943573
2859790	2859813	20	-	27260156	COLO741	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.6501371671725165	[105]	[183,268,183]	9	hSpCas9	negative selection	5943574
2860850	2860873	20	-	27260156	COLO741	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.18656052765577025	[110]	[101,162,107]	-4	hSpCas9	negative selection	5943575
2860478	2860501	20	-	27260156	COLO741	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.24139356660966182	[850]	[1108,827,841]	-5	hSpCas9	negative selection	6007821
2860827	2860850	20	-	27260156	COLO741	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.7286800277593641	[644]	[1533,1641,962]	9	hSpCas9	negative selection	6007822
2859745	2859768	20	+	27260156	COLO741	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.045233075843103876	[184]	[196,256,229]	-1	hSpCas9	negative selection	6007823
2860503	2860526	20	+	27260156	CAL120	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.4413228350189007	[993]	[2148,1358,1601]	6	hSpCas9	negative selection	6064824
2859790	2859813	20	-	27260156	CAL120	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.34657865819234646	[105]	[155,102,240]	5	hSpCas9	negative selection	6064825
2860850	2860873	20	-	27260156	CAL120	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.29882427183483395	[110]	[398,78,67]	4	hSpCas9	negative selection	6064826
2860478	2860501	20	-	27260156	CAL120	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.38099701144968945	[850]	[787,864,782]	-5	hSpCas9	negative selection	6129072
2860827	2860850	20	-	27260156	CAL120	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.5339451772657795	[644]	[1522,1013,1005]	7	hSpCas9	negative selection	6129073
2859745	2859768	20	+	27260156	CAL120	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.4540812659611313	[184]	[495,264,213]	6	hSpCas9	negative selection	6129074
2860503	2860526	20	+	27260156	CADOES1	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.580202613789198	[993]	[1655,1356,1384,1119]	8	hSpCas9	negative selection	6186075
2859790	2859813	20	-	27260156	CADOES1	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.03136692134800789	[105]	[79,111,137,71]	0	hSpCas9	negative selection	6186076
2860850	2860873	20	-	27260156	CADOES1	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.005936069211738726	[110]	[81,146,76,108]	0	hSpCas9	negative selection	6186077
2860478	2860501	20	-	27260156	CADOES1	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.629295122508909	[850]	[551,454,540,497]	-8	hSpCas9	negative selection	6250323
2860827	2860850	20	-	27260156	CADOES1	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.4814998828505775	[644]	[852,948,798,745]	7	hSpCas9	negative selection	6250324
2859745	2859768	20	+	27260156	CADOES1	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.17006242275651817	[184]	[141,108,172,188]	-3	hSpCas9	negative selection	6250325
2860503	2860526	20	+	27260156	EWS502	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.697981907022249	[993]	[1823,1667,1486,1839]	9	hSpCas9	negative selection	6307326
2859790	2859813	20	-	27260156	EWS502	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.10680157008959723	[105]	[103,81,93,139]	-2	hSpCas9	negative selection	6307327
2860850	2860873	20	-	27260156	EWS502	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.15927450325899017	[110]	[200,34,159,123]	2	hSpCas9	negative selection	6307328
2860478	2860501	20	-	27260156	EWS502	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.19716784514130747	[850]	[718,808,718,909]	-4	hSpCas9	negative selection	6371574
2860827	2860850	20	-	27260156	EWS502	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.853747272803536	[644]	[1131,1263,1267,1284]	9	hSpCas9	negative selection	6371575
2859745	2859768	20	+	27260156	EWS502	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.012332722695569398	[184]	[267,54,186,282]	0	hSpCas9	negative selection	6371576
2860503	2860526	20	+	27260156	EW8	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.45063287330607515	[993]	[1581,796,898,1207]	7	hSpCas9	negative selection	6428577
2859790	2859813	20	-	27260156	EW8	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.6441001222626168	[105]	[44,86,47,39]	-8	hSpCas9	negative selection	6428578
2860850	2860873	20	-	27260156	EW8	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-1.1138152439533182	[110]	[51,30,24,61]	-9	hSpCas9	negative selection	6428579
2860478	2860501	20	-	27260156	EW8	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.3944075783323568	[850]	[554,486,502,558]	-6	hSpCas9	negative selection	6492825
2860827	2860850	20	-	27260156	EW8	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.5691320821825623	[644]	[699,640,806,936]	8	hSpCas9	negative selection	6492826
2859745	2859768	20	+	27260156	EW8	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.6666385560693091	[184]	[105,63,115,88]	-8	hSpCas9	negative selection	6492827
2860503	2860526	20	+	27260156	CORL105	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.4856919730632001	[993]	[1453,1525,1785,1770]	8	hSpCas9	negative selection	6549828
2859790	2859813	20	-	27260156	CORL105	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.0827983752900816	[105]	[121,170,120,108]	1	hSpCas9	negative selection	6549829
2860850	2860873	20	-	27260156	CORL105	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.2544680440537903	[110]	[91,113,234,189]	5	hSpCas9	negative selection	6549830
2860478	2860501	20	-	27260156	CORL105	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.6382129979191116	[850]	[483,739,729,612]	-8	hSpCas9	negative selection	6614076
2860827	2860850	20	-	27260156	CORL105	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.4252427925073666	[644]	[837,931,1195,1112]	7	hSpCas9	negative selection	6614077
2859745	2859768	20	+	27260156	CORL105	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.08546877585590806	[184]	[268,146,142,250]	-1	hSpCas9	negative selection	6614078
2860503	2860526	20	+	27260156	HS294T	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.29589060456119776	[993]	[464,487,429,508]	4	hSpCas9	negative selection	6671079
2859790	2859813	20	-	27260156	HS294T	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.21780945973375632	[105]	[27,25,46,41]	-3	hSpCas9	negative selection	6671080
2860850	2860873	20	-	27260156	HS294T	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.5173443081844287	[110]	[22,20,40,36]	-6	hSpCas9	negative selection	6671081
2860478	2860501	20	-	27260156	HS294T	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.7984211095160823	[850]	[115,224,191,236]	-8	hSpCas9	negative selection	6735327
2860827	2860850	20	-	27260156	HS294T	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.3812532981366205	[644]	[204,249,519,339]	5	hSpCas9	negative selection	6735328
2859745	2859768	20	+	27260156	HS294T	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.4652846194522693	[184]	[27,39,73,70]	-6	hSpCas9	negative selection	6735329
2860503	2860526	20	+	27260156	HCC44	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5241355872533431	[993]	[1570,1326,2208,1489]	8	hSpCas9	negative selection	6792330
2859790	2859813	20	-	27260156	HCC44	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.374199614667726	[105]	[194,170,87,155]	6	hSpCas9	negative selection	6792331
2860850	2860873	20	-	27260156	HCC44	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-1.2643624914310392	[110]	[21,52,107,32]	-9	hSpCas9	negative selection	6792332
2860478	2860501	20	-	27260156	HCC44	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5952464128741022	[850]	[646,546,902,509]	-7	hSpCas9	negative selection	6856578
2860827	2860850	20	-	27260156	HCC44	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.6909132095729034	[644]	[588,249,577,449]	-7	hSpCas9	negative selection	6856579
2859745	2859768	20	+	27260156	HCC44	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.4936914194293047	[184]	[142,155,189,110]	-6	hSpCas9	negative selection	6856580
2860503	2860526	20	+	27260156	G402	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.736105069527123	[993]	[2979,1702,1948,1582]	8	hSpCas9	negative selection	6913581
2859790	2859813	20	-	27260156	G402	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.2578155115835641	[105]	[507,5,25,121]	3	hSpCas9	negative selection	6913582
2860850	2860873	20	-	27260156	G402	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.3620905004556292	[110]	[93,107,77,137]	-4	hSpCas9	negative selection	6913583
2860478	2860501	20	-	27260156	G402	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.44138071934424855	[850]	[813,638,908,696]	-5	hSpCas9	negative selection	6977829
2860827	2860850	20	-	27260156	G402	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.12067220222116509	[644]	[751,1035,941,692]	1	hSpCas9	negative selection	6977830
2859745	2859768	20	+	27260156	G402	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.38251179677925085	[184]	[288,459,102,330]	5	hSpCas9	negative selection	6977831
2860503	2860526	20	+	27260156	L33	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.19546437202638622	[993]	[1257,430,731,1075]	4	hSpCas9	negative selection	7034832
2859790	2859813	20	-	27260156	L33	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.34962832045765646	[105]	[119,57,117,91]	7	hSpCas9	negative selection	7034833
2860850	2860873	20	-	27260156	L33	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.46482908959216895	[110]	[222,39,107,118]	8	hSpCas9	negative selection	7034834
2860478	2860501	20	-	27260156	L33	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.24865564206513735	[850]	[687,272,496,720]	-5	hSpCas9	negative selection	7099080
2860827	2860850	20	-	27260156	L33	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.9277937187631304	[644]	[1160,456,856,1269]	9	hSpCas9	negative selection	7099081
2859745	2859768	20	+	27260156	L33	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.13261220762972292	[184]	[243,82,140,139]	3	hSpCas9	negative selection	7099082
2860503	2860526	20	+	27260156	K562	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5955165201560904	[993]	[1454,1338,1396,1164]	7	hSpCas9	negative selection	7156083
2859790	2859813	20	-	27260156	K562	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.3308676130980981	[105]	[160,24,20,93]	-4	hSpCas9	negative selection	7156084
2860850	2860873	20	-	27260156	K562	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.10876146096682726	[110]	[133,160,21,58]	-1	hSpCas9	negative selection	7156085
2860478	2860501	20	-	27260156	K562	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.000949378513268484	[850]	[829,1220,558,469]	0	hSpCas9	negative selection	7220331
2860827	2860850	20	-	27260156	K562	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.33804285600097633	[644]	[652,1037,715,518]	4	hSpCas9	negative selection	7220332
2859745	2859768	20	+	27260156	K562	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.07977140705537789	[184]	[87,317,190,104]	1	hSpCas9	negative selection	7220333
2860503	2860526	20	+	27260156	HT29	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.43473682567618055	[993]	[1670,1808,1649,1433]	8	hSpCas9	negative selection	7277334
2859790	2859813	20	-	27260156	HT29	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.7841769028023657	[105]	[85,73,32,102]	-8	hSpCas9	negative selection	7277335
2860850	2860873	20	-	27260156	HT29	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.31313119178120363	[110]	[87,67,122,144]	-6	hSpCas9	negative selection	7277336
2860478	2860501	20	-	27260156	HT29	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.6543043789751856	[850]	[656,781,645,561]	-8	hSpCas9	negative selection	7341582
2860827	2860850	20	-	27260156	HT29	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.4834898941068053	[644]	[472,563,655,541]	-7	hSpCas9	negative selection	7341583
2859745	2859768	20	+	27260156	HT29	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.39440655813756953	[184]	[115,235,210,126]	-6	hSpCas9	negative selection	7341584
2860503	2860526	20	+	27260156	MHHES1	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.16354266133492645	[993]	[1291,1350,1407,1008]	3	hSpCas9	negative selection	7398585
2859790	2859813	20	-	27260156	MHHES1	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-1.0381724142443307	[105]	[93,41,50,48]	-9	hSpCas9	negative selection	7398586
2860850	2860873	20	-	27260156	MHHES1	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.2776083078715079	[110]	[161,238,68,143]	5	hSpCas9	negative selection	7398587
2860478	2860501	20	-	27260156	MHHES1	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.32864056503913774	[850]	[578,885,850,719]	-6	hSpCas9	negative selection	7462833
2860827	2860850	20	-	27260156	MHHES1	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.18317964848378682	[644]	[672,1176,818,665]	3	hSpCas9	negative selection	7462834
2859745	2859768	20	+	27260156	MHHES1	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.02097581117641001	[184]	[156,393,150,161]	0	hSpCas9	negative selection	7462835
2860503	2860526	20	+	27260156	MEWO	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3862670491179572	[993]	[1279,1334,1042]	7	hSpCas9	negative selection	7519836
2859790	2859813	20	-	27260156	MEWO	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.22006722577558735	[105]	[93,108,53]	-5	hSpCas9	negative selection	7519837
2860850	2860873	20	-	27260156	MEWO	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.19977619673205993	[110]	[99,129,123]	4	hSpCas9	negative selection	7519838
2860478	2860501	20	-	27260156	MEWO	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.500348074424	[850]	[728,475,515]	-8	hSpCas9	negative selection	7584084
2860827	2860850	20	-	27260156	MEWO	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.8317474970327174	[644]	[1047,1029,1138]	9	hSpCas9	negative selection	7584085
2859745	2859768	20	+	27260156	MEWO	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.33245706069458736	[184]	[149,89,174]	-6	hSpCas9	negative selection	7584086
2860503	2860526	20	+	27260156	LNCAPCLONEFGC	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.45047431250493797	[993]	[1119,1095,1473,1277]	7	hSpCas9	negative selection	7641087
2859790	2859813	20	-	27260156	LNCAPCLONEFGC	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.21317354115270026	[105]	[43,128,109,49]	-3	hSpCas9	negative selection	7641088
2860850	2860873	20	-	27260156	LNCAPCLONEFGC	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.3929391691844062	[110]	[43,52,113,102]	-6	hSpCas9	negative selection	7641089
2860478	2860501	20	-	27260156	LNCAPCLONEFGC	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5660088674362163	[850]	[495,493,555,543]	-7	hSpCas9	negative selection	7705335
2860827	2860850	20	-	27260156	LNCAPCLONEFGC	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.22719778350817948	[644]	[574,550,469,390]	-4	hSpCas9	negative selection	7705336
2859745	2859768	20	+	27260156	LNCAPCLONEFGC	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.5678129209725857	[184]	[80,92,172,115]	-7	hSpCas9	negative selection	7705337
2860503	2860526	20	+	27260156	PANC0327	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5879817591634247	[993]	[1455,1361,1012,1482]	8	hSpCas9	negative selection	7762338
2859790	2859813	20	-	27260156	PANC0327	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.04766546196070909	[105]	[104,150,92,33]	0	hSpCas9	negative selection	7762339
2860850	2860873	20	-	27260156	PANC0327	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-1.6637233774457285	[110]	[34,44,24,17]	-9	hSpCas9	negative selection	7762340
2860478	2860501	20	-	27260156	PANC0327	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.3959297477719376	[850]	[648,544,635,477]	-5	hSpCas9	negative selection	7826586
2860827	2860850	20	-	27260156	PANC0327	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.19614582151353105	[644]	[539,382,707,1019]	3	hSpCas9	negative selection	7826587
2859745	2859768	20	+	27260156	PANC0327	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.425841622000557	[184]	[130,68,182,113]	-6	hSpCas9	negative selection	7826588
2860503	2860526	20	+	27260156	NCIH2009	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.21861513803424426	[993]	[1887,1616,1393]	3	hSpCas9	negative selection	7883589
2859790	2859813	20	-	27260156	NCIH2009	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.25999362439407125	[105]	[152,227,144]	3	hSpCas9	negative selection	7883590
2860850	2860873	20	-	27260156	NCIH2009	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.28852103305614474	[110]	[297,100,191]	4	hSpCas9	negative selection	7883591
2860478	2860501	20	-	27260156	NCIH2009	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.8612764458377108	[850]	[755,567,659]	-8	hSpCas9	negative selection	7947837
2860827	2860850	20	-	27260156	NCIH2009	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.01756447417795498	[644]	[1278,722,808]	0	hSpCas9	negative selection	7947838
2859745	2859768	20	+	27260156	NCIH2009	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.08413520529708274	[184]	[310,264,252]	1	hSpCas9	negative selection	7947839
2860503	2860526	20	+	27260156	NCIH1373	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.6223521507548893	[993]	[1582,1512,2260,385]	6	hSpCas9	negative selection	8004840
2859790	2859813	20	-	27260156	NCIH1373	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.09558627036281697	[105]	[121,77,71,47]	-1	hSpCas9	negative selection	8004841
2860850	2860873	20	-	27260156	NCIH1373	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	1.4415382411131874	[110]	[292,93,752,55]	9	hSpCas9	negative selection	8004842
2860478	2860501	20	-	27260156	NCIH1373	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-1.249561925664928	[850]	[470,394,275,125]	-8	hSpCas9	negative selection	8069088
2860827	2860850	20	-	27260156	NCIH1373	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.34638884989970153	[644]	[357,658,523,182]	-3	hSpCas9	negative selection	8069089
2859745	2859768	20	+	27260156	NCIH1373	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.18065251114193082	[184]	[121,203,282,83]	1	hSpCas9	negative selection	8069090
2860503	2860526	20	+	27260156	PATU8902	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5052435525964483	[993]	[1701,2366,1463,2510]	5	hSpCas9	negative selection	8126091
2859790	2859813	20	-	27260156	PATU8902	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.9809674542943205	[105]	[38,176,70,4]	-7	hSpCas9	negative selection	8126092
2860850	2860873	20	-	27260156	PATU8902	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.4636124196238449	[110]	[111,86,78,186]	-4	hSpCas9	negative selection	8126093
2860478	2860501	20	-	27260156	PATU8902	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.9135822202475257	[850]	[815,594,536,578]	-7	hSpCas9	negative selection	8190339
2860827	2860850	20	-	27260156	PATU8902	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-1.1733002269514967	[644]	[325,361,507,361]	-8	hSpCas9	negative selection	8190340
2859745	2859768	20	+	27260156	PATU8902	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.8669040357626079	[184]	[274,33,61,220]	-7	hSpCas9	negative selection	8190341
2860503	2860526	20	+	27260156	PANC1	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.30444829016115493	[993]	[827,1501,1106,887]	5	hSpCas9	negative selection	8247342
2859790	2859813	20	-	27260156	PANC1	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.23129677932703196	[105]	[78,163,167,38]	3	hSpCas9	negative selection	8247343
2860850	2860873	20	-	27260156	PANC1	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.3791088034924486	[110]	[17,85,143,51]	-5	hSpCas9	negative selection	8247344
2860478	2860501	20	-	27260156	PANC1	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.6747672294811636	[850]	[596,514,400,338]	-7	hSpCas9	negative selection	8311590
2860827	2860850	20	-	27260156	PANC1	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.0454234135219066	[644]	[463,595,593,503]	0	hSpCas9	negative selection	8311591
2859745	2859768	20	+	27260156	PANC1	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.7076530970916894	[184]	[87,49,113,121]	-7	hSpCas9	negative selection	8311592
2860503	2860526	20	+	27260156	PANC0813	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.26833872832488503	[993]	[1481,1251,1519,1377]	4	hSpCas9	negative selection	8368593
2859790	2859813	20	-	27260156	PANC0813	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.01082867568726087	[105]	[80,145,83,175]	0	hSpCas9	negative selection	8368594
2860850	2860873	20	-	27260156	PANC0813	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.33013212840501627	[110]	[103,127,317,103]	5	hSpCas9	negative selection	8368595
2860478	2860501	20	-	27260156	PANC0813	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.9351360618480782	[850]	[710,416,568,416]	-8	hSpCas9	negative selection	8432841
2860827	2860850	20	-	27260156	PANC0813	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.3172995197533975	[644]	[864,909,1018,971]	5	hSpCas9	negative selection	8432842
2859745	2859768	20	+	27260156	PANC0813	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.08229669778750259	[184]	[241,285,201,99]	-1	hSpCas9	negative selection	8432843
2860503	2860526	20	+	27260156	RDES	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.6374359659948792	[993]	[1418,1518,1925,2399]	8	hSpCas9	negative selection	8489844
2859790	2859813	20	-	27260156	RDES	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.10932749620118054	[105]	[119,74,124,133]	-2	hSpCas9	negative selection	8489845
2860850	2860873	20	-	27260156	RDES	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.18619731921280858	[110]	[127,91,218,149]	3	hSpCas9	negative selection	8489846
2860478	2860501	20	-	27260156	RDES	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5969024434805136	[850]	[611,606,711,649]	-8	hSpCas9	negative selection	8554092
2860827	2860850	20	-	27260156	RDES	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.6941378028566714	[644]	[1096,993,1324,1427]	9	hSpCas9	negative selection	8554093
2859745	2859768	20	+	27260156	RDES	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.00620829892496233	[184]	[156,148,335,232]	0	hSpCas9	negative selection	8554094
2860503	2860526	20	+	27260156	PC3	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.30139239174386145	[993]	[823,912,2267,1359]	6	hSpCas9	negative selection	8611095
2859790	2859813	20	-	27260156	PC3	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.013461749081764562	[105]	[61,104,169,124]	0	hSpCas9	negative selection	8611096
2860850	2860873	20	-	27260156	PC3	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.2683445824859785	[110]	[46,43,70,217]	-6	hSpCas9	negative selection	8611097
2860478	2860501	20	-	27260156	PC3	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.19410677933421827	[850]	[578,613,1247,711]	-4	hSpCas9	negative selection	8675343
2860827	2860850	20	-	27260156	PC3	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.8285297732243562	[644]	[770,1062,1857,1204]	9	hSpCas9	negative selection	8675344
2859745	2859768	20	+	27260156	PC3	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.08535765543952745	[184]	[141,240,235,176]	2	hSpCas9	negative selection	8675345
2860503	2860526	20	+	27260156	PATU8988T	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.44666896165418235	[993]	[1307,1449,1104,1395]	7	hSpCas9	negative selection	8732346
2859790	2859813	20	-	27260156	PATU8988T	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.6122296866527339	[105]	[64,209,146,213]	8	hSpCas9	negative selection	8732347
2860850	2860873	20	-	27260156	PATU8988T	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.6618752383424966	[110]	[20,76,90,83]	-7	hSpCas9	negative selection	8732348
2860478	2860501	20	-	27260156	PATU8988T	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5828359854876115	[850]	[542,675,444,544]	-7	hSpCas9	negative selection	8796594
2860827	2860850	20	-	27260156	PATU8988T	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.24719334046796	[644]	[653,920,582,826]	4	hSpCas9	negative selection	8796595
2859745	2859768	20	+	27260156	PATU8988T	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.11193410969709228	[184]	[213,148,224,178]	2	hSpCas9	negative selection	8796596
2860503	2860526	20	+	27260156	T47D	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3306920562154876	[993]	[1573,1377,1496,1379]	7	hSpCas9	negative selection	8853597
2859790	2859813	20	-	27260156	T47D	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.21683410643812429	[105]	[126,164,119,160]	4	hSpCas9	negative selection	8853598
2860850	2860873	20	-	27260156	T47D	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.19403105702872336	[110]	[99,117,130,101]	-4	hSpCas9	negative selection	8853599
2860478	2860501	20	-	27260156	T47D	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.30103609985869684	[850]	[855,723,843,800]	-6	hSpCas9	negative selection	8917845
2860827	2860850	20	-	27260156	T47D	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.6564899993806155	[644]	[1195,1090,1232,1225]	9	hSpCas9	negative selection	8917846
2859745	2859768	20	+	27260156	T47D	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.11414045901227587	[184]	[230,156,172,240]	-3	hSpCas9	negative selection	8917847
2860503	2860526	20	+	27260156	SU8686	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3970992616498781	[993]	[1243,1216,1392,1355]	6	hSpCas9	negative selection	8974848
2859790	2859813	20	-	27260156	SU8686	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	-0.6065588741191821	[105]	[77,68,40,88]	-7	hSpCas9	negative selection	8974849
2860850	2860873	20	-	27260156	SU8686	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.0027645467586396855	[110]	[81,117,76,172]	0	hSpCas9	negative selection	8974850
2860478	2860501	20	-	27260156	SU8686	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.7192547749167395	[850]	[471,499,431,671]	-8	hSpCas9	negative selection	9039096
2860827	2860850	20	-	27260156	SU8686	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	-0.11589478640427453	[644]	[565,546,665,586]	-2	hSpCas9	negative selection	9039097
2859745	2859768	20	+	27260156	SU8686	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.15316868732441824	[184]	[174,201,114,157]	-3	hSpCas9	negative selection	9039098
2860503	2860526	20	+	27260156	SKES1	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.3517728267177289	[993]	[1611,1147,1156,1176]	7	hSpCas9	negative selection	9096099
2859790	2859813	20	-	27260156	SKES1	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.09852308016266553	[105]	[119,110,124,97]	2	hSpCas9	negative selection	9096100
2860850	2860873	20	-	27260156	SKES1	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.1431279707675892	[110]	[122,104,95,81]	-3	hSpCas9	negative selection	9096101
2860478	2860501	20	-	27260156	SKES1	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.43290064825785474	[850]	[583,642,638,636]	-7	hSpCas9	negative selection	9160347
2860827	2860850	20	-	27260156	SKES1	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.8213098045695488	[644]	[1274,1142,1124,1025]	9	hSpCas9	negative selection	9160348
2859745	2859768	20	+	27260156	SKES1	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.2403606593498684	[184]	[204,157,175,97]	-5	hSpCas9	negative selection	9160349
2860503	2860526	20	+	27260156	TOV112D	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.4852103590438739	[993]	[1378,1590,1137,1507]	8	hSpCas9	negative selection	9217350
2859790	2859813	20	-	27260156	TOV112D	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.7466662587608268	[105]	[333,79,64,220]	9	hSpCas9	negative selection	9217351
2860850	2860873	20	-	27260156	TOV112D	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	0.3017680093570936	[110]	[207,173,152,30]	6	hSpCas9	negative selection	9217352
2860478	2860501	20	-	27260156	TOV112D	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.3236308630763528	[850]	[764,722,771,485]	-6	hSpCas9	negative selection	9281598
2860827	2860850	20	-	27260156	TOV112D	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.43835573389355714	[644]	[690,1435,711,785]	7	hSpCas9	negative selection	9281599
2859745	2859768	20	+	27260156	TOV112D	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.1108486259928938	[184]	[255,246,139,173]	2	hSpCas9	negative selection	9281600
2860503	2860526	20	+	27260156	TC71	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.2244816796136797	[993]	[1139,1336,1222,1284]	5	hSpCas9	negative selection	9338601
2859790	2859813	20	-	27260156	TC71	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.10343341226309466	[105]	[116,92,187,85]	2	hSpCas9	negative selection	9338602
2860850	2860873	20	-	27260156	TC71	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.06966357314076399	[110]	[89,82,138,142]	-2	hSpCas9	negative selection	9338603
2860478	2860501	20	-	27260156	TC71	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.23708280821856031	[850]	[633,764,872,826]	-6	hSpCas9	negative selection	9402849
2860827	2860850	20	-	27260156	TC71	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	1.0101191006285022	[644]	[1393,1349,1428,1395]	9	hSpCas9	negative selection	9402850
2859745	2859768	20	+	27260156	TC71	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	-0.07718163706093639	[184]	[141,265,166,177]	-2	hSpCas9	negative selection	9402851
2860503	2860526	20	+	27260156	TC32	viability	TCCGGAGTGGCCATCCTCACAGG	VPS16	ENSG00000215305	0.5636921845593066	[993]	[1364,964,1553,1767]	8	hSpCas9	negative selection	9459852
2859790	2859813	20	-	27260156	TC32	viability	CATACCAATGGGGCCCCCATAGG	VPS16	ENSG00000215305	0.17690679794097974	[105]	[101,82,231,56]	3	hSpCas9	negative selection	9459853
2860850	2860873	20	-	27260156	TC32	viability	GGCCCTTACCACTGCGGAGCAGG	VPS16	ENSG00000215305	-0.2573692920380224	[110]	[118,60,86,81]	-5	hSpCas9	negative selection	9459854
2860478	2860501	20	-	27260156	TC32	viability	CAAACTCAGTGTGAAAGATCCGG	VPS16	ENSG00000215305	-0.5232994403497961	[850]	[635,351,762,543]	-7	hSpCas9	negative selection	9524100
2860827	2860850	20	-	27260156	TC32	viability	CTGCATGGTCCAAGAGGTAAAGG	VPS16	ENSG00000215305	0.39206133490700795	[644]	[792,618,1006,818]	6	hSpCas9	negative selection	9524101
2859745	2859768	20	+	27260156	TC32	viability	GGGACCTGAAGGAGGAACTCAGG	VPS16	ENSG00000215305	0.09947211853292193	[184]	[147,164,288,160]	1	hSpCas9	negative selection	9524102
2859724	2859747	20	+	27869803	HPAFII	viability after 27 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-1.0792087112869355	[212]	[4,92,NaN]	-6	hSpCas9	negative selection	9576858
2860101	2860124	20	-	27869803	HPAFII	viability after 27 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-4.154288370401413	[233]	[1,10,NaN]	-9	hSpCas9	negative selection	9576859
2860340	2860363	20	+	27869803	HPAFII	viability after 27 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.750370576450835	[433]	[205,76,NaN]	-5	hSpCas9	negative selection	9576860
2860504	2860527	20	+	27869803	HPAFII	viability after 27 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.538340737007411	[434]	[912,456,NaN]	9	hSpCas9	negative selection	9576861
2861020	2861043	20	+	27869803	HPAFII	viability after 27 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.5241917926723997	[384]	[265,311,NaN]	4	hSpCas9	negative selection	9576862
2859724	2859747	20	+	27869803	HPAFII	viability after 15 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.6187457774011906	[212]	[108,173,NaN]	-6	hSpCas9	negative selection	9659307
2860101	2860124	20	-	27869803	HPAFII	viability after 15 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.6693327076932634	[233]	[41,37,NaN]	-9	hSpCas9	negative selection	9659308
2860340	2860363	20	+	27869803	HPAFII	viability after 15 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.18390838482502148	[433]	[491,359,NaN]	-2	hSpCas9	negative selection	9659309
2860504	2860527	20	+	27869803	HPAFII	viability after 15 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.0645710962500026	[434]	[1652,557,NaN]	9	hSpCas9	negative selection	9659310
2861020	2861043	20	+	27869803	HPAFII	viability after 15 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.0914545519629898	[384]	[787,224,NaN]	1	hSpCas9	negative selection	9659311
2859724	2859747	20	+	27869803	ASPC1	viability after 36 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	0.04622640765329983	[553]	[256,179,172]	0	hSpCas9	negative selection	9741756
2860101	2860124	20	-	27869803	ASPC1	viability after 36 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.033941725565115	[522]	[8,52,6]	-9	hSpCas9	negative selection	9741757
2860340	2860363	20	+	27869803	ASPC1	viability after 36 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.20161093179608403	[956]	[251,451,418]	2	hSpCas9	negative selection	9741758
2860504	2860527	20	+	27869803	ASPC1	viability after 36 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.7416970401486147	[1148]	[459,742,753]	7	hSpCas9	negative selection	9741759
2861020	2861043	20	+	27869803	ASPC1	viability after 36 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.19686303944112882	[990]	[613,108,467]	2	hSpCas9	negative selection	9741760
2859724	2859747	20	+	27869803	PATU8988S	viability after 35 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.894244116908332	[352]	[72,79,NaN]	-7	hSpCas9	negative selection	9824205
2860101	2860124	20	-	27869803	PATU8988S	viability after 35 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.36571113299604885	[495]	[169,139,NaN]	-4	hSpCas9	negative selection	9824206
2860340	2860363	20	+	27869803	PATU8988S	viability after 35 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.4930547974846723	[780]	[311,573,NaN]	5	hSpCas9	negative selection	9824207
2860504	2860527	20	+	27869803	PATU8988S	viability after 35 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.11026918876895464	[1295]	[529,596,NaN]	1	hSpCas9	negative selection	9824208
2861020	2861043	20	+	27869803	PATU8988S	viability after 35 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.3055781123476826	[670]	[333,333,NaN]	3	hSpCas9	negative selection	9824209
2859724	2859747	20	+	27869803	PATU8988S	viability after 31 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	0.06599389352756002	[352]	[72,241,NaN]	0	hSpCas9	negative selection	9906654
2860101	2860124	20	-	27869803	PATU8988S	viability after 31 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	0.0396519981487075	[495]	[241,153,NaN]	0	hSpCas9	negative selection	9906655
2860340	2860363	20	+	27869803	PATU8988S	viability after 31 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	0.569419817514418	[780]	[279,693,NaN]	6	hSpCas9	negative selection	9906656
2860504	2860527	20	+	27869803	PATU8988S	viability after 31 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	0.16335290044620532	[1295]	[411,790,NaN]	2	hSpCas9	negative selection	9906657
2861020	2861043	20	+	27869803	PATU8988S	viability after 31 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	-0.0871100415519318	[670]	[250,252,NaN]	-1	hSpCas9	negative selection	9906658
2859724	2859747	20	+	27869803	HPAFII	viability after 35 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-0.9444517533684549	[212]	[0,117,NaN]	-5	hSpCas9	negative selection	9989103
2860101	2860124	20	-	27869803	HPAFII	viability after 35 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-6.88827616658673	[233]	[0,0,NaN]	-9	hSpCas9	negative selection	9989104
2860340	2860363	20	+	27869803	HPAFII	viability after 35 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-1.4125530697492978	[433]	[90,72,NaN]	-6	hSpCas9	negative selection	9989105
2860504	2860527	20	+	27869803	HPAFII	viability after 35 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.88546431912249	[434]	[1037,560,NaN]	9	hSpCas9	negative selection	9989106
2861020	2861043	20	+	27869803	HPAFII	viability after 35 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	1.1093020050599143	[384]	[340,509,NaN]	7	hSpCas9	negative selection	9989107
2859724	2859747	20	+	27869803	HPAFII	viability after 31 days	ATGAGCTGTACAGCATGGACTGG	VPS16	ENSG00000215305	-1.5262989892036558	[212]	[7,77,NaN]	-7	hSpCas9	negative selection	10071552
2860101	2860124	20	-	27869803	HPAFII	viability after 31 days	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-7.036993519908147	[233]	[0,0,NaN]	-9	hSpCas9	negative selection	10071553
2860340	2860363	20	+	27869803	HPAFII	viability after 31 days	CTTCCGGAGACACTTCAGCATGG	VPS16	ENSG00000215305	-0.8798877887995598	[433]	[184,74,NaN]	-5	hSpCas9	negative selection	10071554
2860504	2860527	20	+	27869803	HPAFII	viability after 31 days	CCGGAGTGGCCATCCTCACAGGG	VPS16	ENSG00000215305	1.294034150530004	[434]	[757,424,NaN]	8	hSpCas9	negative selection	10071555
2861020	2861043	20	+	27869803	HPAFII	viability after 31 days	CTCCTTCACCTACCGACACCTGG	VPS16	ENSG00000215305	0.739997678510382	[384]	[290,436,NaN]	5	hSpCas9	negative selection	10071556
2860235	2860258	20	+	28162770	P31FUJ	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.9246799090520466	[167]	[51]	-8	hSpCas9	negative selection	10263690
2859737	2859760	20	+	28162770	P31FUJ	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-0.5765009219729602	[216]	[170]	-5	hSpCas9	negative selection	10263691
2859758	2859781	20	+	28162770	P31FUJ	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-3.480729717857964	[56]	[5]	-9	hSpCas9	negative selection	10263692
2860101	2860124	20	-	28162770	P31FUJ	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.8113384359761016	[223]	[74]	-8	hSpCas9	negative selection	10263693
2861660	2861683	20	+	28162770	P31FUJ	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	1.089125890472984	[27]	[69]	9	hSpCas9	negative selection	10263694
2863986	2864009	20	+	28162770	P31FUJ	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.6428904877214892	[193]	[145]	-5	hSpCas9	negative selection	10263695
2860235	2860258	20	+	28162770	TF1	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10433056
2859737	2859760	20	+	28162770	TF1	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10433057
2859758	2859781	20	+	28162770	TF1	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10433058
2860101	2860124	20	-	28162770	TF1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10433059
2861660	2861683	20	+	28162770	TF1	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10433060
2863986	2864009	20	+	28162770	TF1	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10433061
2860235	2860258	20	+	28162770	SKM1	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-2.2110439887679045	[54]	[20]	-8	hSpCas9	negative selection	10602422
2859737	2859760	20	+	28162770	SKM1	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-2.1301239933843372	[51]	[20]	-8	hSpCas9	negative selection	10602423
2859758	2859781	20	+	28162770	SKM1	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.406964198743162	[20]	[6]	-8	hSpCas9	negative selection	10602424
2860101	2860124	20	-	28162770	SKM1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.0075573511780822	[57]	[50]	-6	hSpCas9	negative selection	10602425
2861660	2861683	20	+	28162770	SKM1	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.9374789154419414	[12]	[11]	-6	hSpCas9	negative selection	10602426
2863986	2864009	20	+	28162770	SKM1	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.5171471164935846	[50]	[62]	-4	hSpCas9	negative selection	10602427
2860235	2860258	20	+	28162770	SKM1	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-2.2110439887679045	[54]	[20]	-8	hSpCas9	negative selection	10771788
2859737	2859760	20	+	28162770	SKM1	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-2.1301239933843372	[51]	[20]	-8	hSpCas9	negative selection	10771789
2859758	2859781	20	+	28162770	SKM1	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.406964198743162	[20]	[6]	-8	hSpCas9	negative selection	10771790
2860101	2860124	20	-	28162770	SKM1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.0075573511780822	[57]	[50]	-6	hSpCas9	negative selection	10771791
2861660	2861683	20	+	28162770	SKM1	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.9374789154419414	[12]	[11]	-6	hSpCas9	negative selection	10771792
2863986	2864009	20	+	28162770	SKM1	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.5171471164935846	[50]	[62]	-4	hSpCas9	negative selection	10771793
2860235	2860258	20	+	28162770	PL21	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.8442545048691334	[197]	[47]	-5	hSpCas9	negative selection	10941154
2859737	2859760	20	+	28162770	PL21	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-0.6151205056536302	[182]	[51]	-4	hSpCas9	negative selection	10941155
2859758	2859781	20	+	28162770	PL21	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.2852872126809216	[55]	[4]	-8	hSpCas9	negative selection	10941156
2860101	2860124	20	-	28162770	PL21	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.6677568495033346	[218]	[14]	-9	hSpCas9	negative selection	10941157
2861660	2861683	20	+	28162770	PL21	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.06289479134447351	[35]	[14]	0	hSpCas9	negative selection	10941158
2863986	2864009	20	+	28162770	PL21	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-1.2544262489761608	[147]	[26]	-7	hSpCas9	negative selection	10941159
2860235	2860258	20	+	28162770	P31FUJ	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.9246799090520466	[167]	[51]	-8	hSpCas9	negative selection	11110520
2859737	2859760	20	+	28162770	P31FUJ	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-0.5765009219729602	[216]	[170]	-5	hSpCas9	negative selection	11110521
2859758	2859781	20	+	28162770	P31FUJ	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-3.480729717857964	[56]	[5]	-9	hSpCas9	negative selection	11110522
2860101	2860124	20	-	28162770	P31FUJ	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.8113384359761016	[223]	[74]	-8	hSpCas9	negative selection	11110523
2861660	2861683	20	+	28162770	P31FUJ	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	1.089125890472984	[27]	[69]	9	hSpCas9	negative selection	11110524
2863986	2864009	20	+	28162770	P31FUJ	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.6428904877214892	[193]	[145]	-5	hSpCas9	negative selection	11110525
2860235	2860258	20	+	28162770	OCIAML5	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	0.0786707666988894	[63]	[121]	0	hSpCas9	negative selection	11279886
2859737	2859760	20	+	28162770	OCIAML5	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-2.1657270497677588	[86]	[34]	-8	hSpCas9	negative selection	11279887
2859758	2859781	20	+	28162770	OCIAML5	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-4.7100475659915695	[28]	[1]	-9	hSpCas9	negative selection	11279888
2860101	2860124	20	-	28162770	OCIAML5	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.1306020702379787	[130]	[26]	-9	hSpCas9	negative selection	11279889
2861660	2861683	20	+	28162770	OCIAML5	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	0.5629709284148463	[5]	[15]	5	hSpCas9	negative selection	11279890
2863986	2864009	20	+	28162770	OCIAML5	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	0.2615902109315702	[121]	[263]	2	hSpCas9	negative selection	11279891
2860235	2860258	20	+	28162770	EOL1	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.22840415126806426	[337]	[151]	-2	hSpCas9	negative selection	11449252
2859737	2859760	20	+	28162770	EOL1	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.1936336547777795	[177]	[40]	-7	hSpCas9	negative selection	11449253
2859758	2859781	20	+	28162770	EOL1	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.7916592624288743	[91]	[6]	-9	hSpCas9	negative selection	11449254
2860101	2860124	20	-	28162770	EOL1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.5128575407367637	[389]	[143]	-4	hSpCas9	negative selection	11449255
2861660	2861683	20	+	28162770	EOL1	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	0.12484642205636609	[46]	[26]	1	hSpCas9	negative selection	11449256
2863986	2864009	20	+	28162770	EOL1	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.8029263736183738	[201]	[60]	-5	hSpCas9	negative selection	11449257
2860235	2860258	20	+	28162770	MOLM13	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-2.0533475215661903	[309]	[53]	-7	hSpCas9	negative selection	11618618
2859737	2859760	20	+	28162770	MOLM13	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-0.4904629210969298	[238]	[122]	-3	hSpCas9	negative selection	11618619
2859758	2859781	20	+	28162770	MOLM13	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	0.3716740662852758	[61]	[57]	2	hSpCas9	negative selection	11618620
2860101	2860124	20	-	28162770	MOLM13	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.0730484952845796	[354]	[60]	-7	hSpCas9	negative selection	11618621
2861660	2861683	20	+	28162770	MOLM13	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.3394655405130256	[41]	[23]	-2	hSpCas9	negative selection	11618622
2863986	2864009	20	+	28162770	MOLM13	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-2.4746251237946613	[245]	[31]	-8	hSpCas9	negative selection	11618623
2860235	2860258	20	+	28162770	HEL	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-0.7656040147044787	[214]	[80]	-5	hSpCas9	negative selection	11787984
2859737	2859760	20	+	28162770	HEL	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-3.1816896034161886	[169]	[11]	-9	hSpCas9	negative selection	11787985
2859758	2859781	20	+	28162770	HEL	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-2.6996533654467214	[70]	[6]	-8	hSpCas9	negative selection	11787986
2860101	2860124	20	-	28162770	HEL	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-0.8691602065310757	[307]	[107]	-5	hSpCas9	negative selection	11787987
2861660	2861683	20	+	28162770	HEL	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-0.9422236687207994	[35]	[11]	-5	hSpCas9	negative selection	11787988
2863986	2864009	20	+	28162770	HEL	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.7188163370077165	[202]	[78]	-5	hSpCas9	negative selection	11787989
2860235	2860258	20	+	28162770	MV411	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.4530021673583169	[181]	[55]	-7	hSpCas9	negative selection	11957350
2859737	2859760	20	+	28162770	MV411	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.2761244052742375	[114]	[39]	-7	hSpCas9	negative selection	11957351
2859758	2859781	20	+	28162770	MV411	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-4.025580943623641	[57]	[2]	-9	hSpCas9	negative selection	11957352
2860101	2860124	20	-	28162770	MV411	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-1.2246308935324473	[171]	[61]	-7	hSpCas9	negative selection	11957353
2861660	2861683	20	+	28162770	MV411	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-3.9620158148461746	[36]	[1]	-9	hSpCas9	negative selection	11957354
2863986	2864009	20	+	28162770	MV411	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	0.043423658761181955	[181]	[157]	0	hSpCas9	negative selection	11957355
2860235	2860258	20	+	28162770	MONOMAC1	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.771272941187651	[133]	[44]	-8	hSpCas9	negative selection	12126716
2859737	2859760	20	+	28162770	MONOMAC1	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.3920528294646963	[86]	[37]	-8	hSpCas9	negative selection	12126717
2859758	2859781	20	+	28162770	MONOMAC1	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-3.897476565200646	[51]	[3]	-9	hSpCas9	negative selection	12126718
2860101	2860124	20	-	28162770	MONOMAC1	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.6843026738935767	[156]	[27]	-9	hSpCas9	negative selection	12126719
2861660	2861683	20	+	28162770	MONOMAC1	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	0.2180006522192901	[14]	[19]	2	hSpCas9	negative selection	12126720
2863986	2864009	20	+	28162770	MONOMAC1	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-1.1445694271654179	[107]	[55]	-7	hSpCas9	negative selection	12126721
2860235	2860258	20	+	28162770	OCIAML2	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-1.3101651530489151	[33]	[75]	-7	hSpCas9	negative selection	12296082
2859737	2859760	20	+	28162770	OCIAML2	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-0.6197732645479705	[27]	[100]	-5	hSpCas9	negative selection	12296083
2859758	2859781	20	+	28162770	OCIAML2	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-5.0555923259633175	[5]	[0]	-9	hSpCas9	negative selection	12296084
2860101	2860124	20	-	28162770	OCIAML2	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-2.6596636496321784	[56]	[49]	-9	hSpCas9	negative selection	12296085
2861660	2861683	20	+	28162770	OCIAML2	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	-1.733664231075955	[8]	[14]	-8	hSpCas9	negative selection	12296086
2863986	2864009	20	+	28162770	OCIAML2	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	-0.024830072192630503	[28]	[157]	0	hSpCas9	negative selection	12296087
2860235	2860258	20	+	28162770	OCIAML3	viability	GCAGTGGAAGAGTGGACCCGTGG	VPS16	ENSG00000215305	-4.1049695596015425	[56]	[9]	-9	hSpCas9	negative selection	12465448
2859737	2859760	20	+	28162770	OCIAML3	viability	CATGGACTGGGACCTGAAGGAGG	VPS16	ENSG00000215305	-1.2985517567979918	[65]	[80]	-7	hSpCas9	negative selection	12465449
2859758	2859781	20	+	28162770	OCIAML3	viability	GGAACTCAGGGATTGCCTGGTGG	VPS16	ENSG00000215305	-6.681470481574503	[33]	[0]	-9	hSpCas9	negative selection	12465450
2860101	2860124	20	-	28162770	OCIAML3	viability	GCAGAGTATATATCGAGCACTGG	VPS16	ENSG00000215305	-3.0433150416877526	[70]	[25]	-9	hSpCas9	negative selection	12465451
2861660	2861683	20	+	28162770	OCIAML3	viability	GGAAAGGCGGCTGATGGTGGTGG	VPS16	ENSG00000215305	0.049848549450561386	[7]	[24]	0	hSpCas9	negative selection	12465452
2863986	2864009	20	+	28162770	OCIAML3	viability	GAGCCATTAACCAGAAGCTGGGG	VPS16	ENSG00000215305	0.46827663793017954	[33]	[141]	4	hSpCas9	negative selection	12465453