Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57617
• Symbol: VPS18
• Description: VPS18 core subunit of CORVET and HOPS complexes

DataSource: http://genomecrispr.dkfz.de/#!/results/VPS18

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40899332	40899355	15	+	26472758	Jiyoye	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.2285502328971693	[187]	[120]	-2	hSpCas9	negative selection	179992
40900592	40900615	15	-	26472758	Jiyoye	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.5580592003334497	[245]	[62]	-7	hSpCas9	negative selection	179993
40899483	40899506	15	-	26472758	Jiyoye	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-0.21842910371262847	[53]	[34]	-1	hSpCas9	negative selection	179994
40899826	40899849	15	+	26472758	Jiyoye	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.9272436575646859	[173]	[68]	-6	hSpCas9	negative selection	179995
40899397	40899420	15	+	26472758	Jiyoye	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.31354086101525797	[205]	[124]	-2	hSpCas9	negative selection	179996
40899540	40899563	15	-	26472758	Jiyoye	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.6243946974949965	[230]	[112]	-4	hSpCas9	negative selection	179997
40899745	40899768	15	+	26472758	Jiyoye	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-0.791604482608624	[100]	[43]	-5	hSpCas9	negative selection	179998
40899853	40899876	15	+	26472758	Jiyoye	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	0.7764091911715925	[23]	[30]	5	hSpCas9	negative selection	179999
40900183	40900206	15	+	26472758	Jiyoye	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.8972652866526478	[204]	[82]	-6	hSpCas9	negative selection	180000
40900540	40900563	15	+	26472758	Jiyoye	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.3752331834214999	[85]	[49]	-3	hSpCas9	negative selection	180001
40899332	40899355	15	+	26472758	KBM7	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-1.6804344480110953	[550,474]	[92,58]	-8	hSpCas9	negative selection	371110
40900592	40900615	15	-	26472758	KBM7	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-2.04298813196888	[850,576]	[46,109]	-8	hSpCas9	negative selection	371111
40899483	40899506	15	-	26472758	KBM7	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.363898733304683	[288,248]	[14,32]	-9	hSpCas9	negative selection	371112
40899826	40899849	15	+	26472758	KBM7	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-1.0201529087454437	[433,270]	[104,57]	-7	hSpCas9	negative selection	371113
40899397	40899420	15	+	26472758	KBM7	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.603246419078049	[906,871]	[245,302]	-5	hSpCas9	negative selection	371114
40899540	40899563	15	-	26472758	KBM7	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.6984678731585954	[605,268]	[133,111]	-5	hSpCas9	negative selection	371115
40899745	40899768	15	+	26472758	KBM7	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.2950756213444432	[605,342]	[73,101]	-7	hSpCas9	negative selection	371116
40899853	40899876	15	+	26472758	KBM7	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.42938128309640533	[304,198]	[104,69]	-4	hSpCas9	negative selection	371117
40900183	40900206	15	+	26472758	KBM7	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-1.3344184771912162	[700,644]	[114,134]	-7	hSpCas9	negative selection	371118
40900540	40900563	15	+	26472758	KBM7	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.6297828913540737	[517,586]	[173,165]	-5	hSpCas9	negative selection	371119
40899332	40899355	15	+	26472758	Raji	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.9026005531990224	[289]	[35]	-6	hSpCas9	negative selection	562228
40900592	40900615	15	-	26472758	Raji	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-2.7703607145754026	[440]	[14]	-9	hSpCas9	negative selection	562229
40899483	40899506	15	-	26472758	Raji	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.7505974597539726	[173]	[5]	-9	hSpCas9	negative selection	562230
40899826	40899849	15	+	26472758	Raji	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-2.190297013267086	[235]	[11]	-8	hSpCas9	negative selection	562231
40899397	40899420	15	+	26472758	Raji	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-1.3677013475751834	[277]	[24]	-7	hSpCas9	negative selection	562232
40899540	40899563	15	-	26472758	Raji	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.9671634179914547	[277]	[32]	-6	hSpCas9	negative selection	562233
40899745	40899768	15	+	26472758	Raji	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-3.409892157835982	[228]	[4]	-9	hSpCas9	negative selection	562234
40899853	40899876	15	+	26472758	Raji	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-1.1296556619272498	[131]	[13]	-7	hSpCas9	negative selection	562235
40900183	40900206	15	+	26472758	Raji	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-2.0100740461745774	[242]	[13]	-8	hSpCas9	negative selection	562236
40900540	40900563	15	+	26472758	Raji	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-2.1853982138542465	[293]	[14]	-8	hSpCas9	negative selection	562237
40899332	40899355	15	+	26472758	K562	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-4.73056938432548	[628]	[19]	-9	hSpCas9	negative selection	753346
40900592	40900615	15	-	26472758	K562	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.2880763531605737	[485]	[167]	-6	hSpCas9	negative selection	753347
40899483	40899506	15	-	26472758	K562	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-3.5168665456951724	[338]	[24]	-8	hSpCas9	negative selection	753348
40899826	40899849	15	+	26472758	K562	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-3.0339679405276545	[358]	[36]	-8	hSpCas9	negative selection	753349
40899397	40899420	15	+	26472758	K562	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.8553544070060453	[867]	[404]	-5	hSpCas9	negative selection	753350
40899540	40899563	15	-	26472758	K562	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.4070589674344776	[343]	[218]	-3	hSpCas9	negative selection	753351
40899745	40899768	15	+	26472758	K562	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.7512292477938463	[330]	[82]	-7	hSpCas9	negative selection	753352
40899853	40899876	15	+	26472758	K562	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-6.674444509608148	[241]	[1]	-9	hSpCas9	negative selection	753353
40900183	40900206	15	+	26472758	K562	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.6560455987826386	[447]	[239]	-4	hSpCas9	negative selection	753354
40900540	40900563	15	+	26472758	K562	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-1.332369841609009	[527]	[176]	-6	hSpCas9	negative selection	753355
40894826	40894849	15	-	26627737	DLD1	viability	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.20323084726330887	[188]	[64,40,47]	-2	hSpCas9	negative selection	790485
40896038	40896061	15	+	26627737	DLD1	viability	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.9321692088398199	[369]	[187,326,160]	8	hSpCas9	negative selection	790486
40898922	40898945	15	+	26627737	DLD1	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.48730434856849475	[357]	[33,222,0]	-5	hSpCas9	negative selection	790487
40898937	40898960	15	-	26627737	DLD1	viability	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.1853510695796725	[1189]	[204,138,147]	-8	hSpCas9	negative selection	790488
40900852	40900875	15	+	26627737	DLD1	viability	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.0925210955660374	[292]	[98,11,19]	-7	hSpCas9	negative selection	790489
40902687	40902710	15	+	26627737	DLD1	viability	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.0402155108198496	[838]	[107,179,100]	-7	hSpCas9	negative selection	790490
40894826	40894849	15	-	26627737	GBM cells	viability after 5 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.7088109915057431	[80]	[62,78]	8	hSpCas9	negative selection	872800
40896038	40896061	15	+	26627737	GBM cells	viability after 5 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.6358794690518919	[266]	[206,237]	8	hSpCas9	negative selection	872801
40898922	40898945	15	+	26627737	GBM cells	viability after 5 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.3165816302092015	[136]	[102,79]	5	hSpCas9	negative selection	872802
40898937	40898960	15	-	26627737	GBM cells	viability after 5 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.2497302064694498	[571]	[123,133]	-9	hSpCas9	negative selection	872803
40900852	40900875	15	+	26627737	GBM cells	viability after 5 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.44011021382498405	[190]	[79,70]	-6	hSpCas9	negative selection	872804
40902687	40902710	15	+	26627737	GBM cells	viability after 5 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.36289322756410586	[234]	[98,96]	-5	hSpCas9	negative selection	872805
40894826	40894849	15	-	26627737	GBM cells	viability after 13 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.8505921508332303	[80]	[97,63]	8	hSpCas9	negative selection	955115
40896038	40896061	15	+	26627737	GBM cells	viability after 13 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.34329625721143947	[266]	[244,133]	4	hSpCas9	negative selection	955116
40898922	40898945	15	+	26627737	GBM cells	viability after 13 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.32057643544249026	[136]	[69,50]	-4	hSpCas9	negative selection	955117
40898937	40898960	15	-	26627737	GBM cells	viability after 13 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-2.6237640680491348	[571]	[67,35]	-9	hSpCas9	negative selection	955118
40900852	40900875	15	+	26627737	GBM cells	viability after 13 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.35822856196531006	[190]	[119,48]	-4	hSpCas9	negative selection	955119
40902687	40902710	15	+	26627737	GBM cells	viability after 13 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.5270480228070378	[234]	[46,41]	-9	hSpCas9	negative selection	955120
40894826	40894849	15	-	26627737	GBM cells	viability after 21 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.8910769758450015	[80]	[78,83]	8	hSpCas9	negative selection	1037430
40896038	40896061	15	+	26627737	GBM cells	viability after 21 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.08067651237142603	[266]	[144,129]	0	hSpCas9	negative selection	1037431
40898922	40898945	15	+	26627737	GBM cells	viability after 21 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-2.3576084538791098	[136]	[13,14]	-9	hSpCas9	negative selection	1037432
40898937	40898960	15	-	26627737	GBM cells	viability after 21 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-3.4238697649242713	[571]	[29,27]	-9	hSpCas9	negative selection	1037433
40900852	40900875	15	+	26627737	GBM cells	viability after 21 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.1802698764692656	[190]	[38,51]	-7	hSpCas9	negative selection	1037434
40902687	40902710	15	+	26627737	GBM cells	viability after 21 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-2.295843928808249	[234]	[25,25]	-9	hSpCas9	negative selection	1037435
40894826	40894849	15	-	26627737	RPE1	viability after 9 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	1.3276089612603612	[236]	[204,161]	7	hSpCas9	negative selection	1119745
40896038	40896061	15	+	26627737	RPE1	viability after 9 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.6688993302375121	[1213]	[142,362]	-5	hSpCas9	negative selection	1119746
40898922	40898945	15	+	26627737	RPE1	viability after 9 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	2.5493722397945047	[16]	[45,11]	9	hSpCas9	negative selection	1119747
40898937	40898960	15	-	26627737	RPE1	viability after 9 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.8770155556465391	[2350]	[405,393]	-6	hSpCas9	negative selection	1119748
40900852	40900875	15	+	26627737	RPE1	viability after 9 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.7727823356980402	[719]	[96,176]	-5	hSpCas9	negative selection	1119749
40902687	40902710	15	+	26627737	RPE1	viability after 9 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.20602081597210586	[1529]	[385,452]	-1	hSpCas9	negative selection	1119750
40894826	40894849	15	-	26627737	RPE1	viability after 12 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	1.0917969439355848	[236]	[142,127]	6	hSpCas9	negative selection	1202060
40896038	40896061	15	+	26627737	RPE1	viability after 12 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.300059460521039	[1213]	[159,375]	-2	hSpCas9	negative selection	1202061
40898922	40898945	15	+	26627737	RPE1	viability after 12 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	3.238742644004515	[16]	[80,2]	9	hSpCas9	negative selection	1202062
40898937	40898960	15	-	26627737	RPE1	viability after 12 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.7518709054111373	[2350]	[462,281]	-5	hSpCas9	negative selection	1202063
40900852	40900875	15	+	26627737	RPE1	viability after 12 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-2.457067617198664	[719]	[25,44]	-9	hSpCas9	negative selection	1202064
40902687	40902710	15	+	26627737	RPE1	viability after 12 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.6428756602476315	[1529]	[305,217]	-4	hSpCas9	negative selection	1202065
40894826	40894849	15	-	26627737	RPE1	viability after 15 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	1.2610408054905378	[236]	[234,88]	7	hSpCas9	negative selection	1284375
40896038	40896061	15	+	26627737	RPE1	viability after 15 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.09273406161470765	[1213]	[297,431]	0	hSpCas9	negative selection	1284376
40898922	40898945	15	+	26627737	RPE1	viability after 15 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	4.362059230903154	[16]	[104,92]	9	hSpCas9	negative selection	1284377
40898937	40898960	15	-	26627737	RPE1	viability after 15 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.320371915166594	[2350]	[666,402]	-2	hSpCas9	negative selection	1284378
40900852	40900875	15	+	26627737	RPE1	viability after 15 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.432910487225299	[719]	[78,71]	-7	hSpCas9	negative selection	1284379
40902687	40902710	15	+	26627737	RPE1	viability after 15 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	0.333192025169865	[1529]	[868,232]	2	hSpCas9	negative selection	1284380
40894826	40894849	15	-	26627737	RPE1	viability after 18 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.6785027214502675	[236]	[112,90]	4	hSpCas9	negative selection	1366690
40896038	40896061	15	+	26627737	RPE1	viability after 18 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.22761724176031328	[1213]	[211,566]	1	hSpCas9	negative selection	1366691
40898922	40898945	15	+	26627737	RPE1	viability after 18 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	2.219378030315439	[16]	[31,9]	9	hSpCas9	negative selection	1366692
40898937	40898960	15	-	26627737	RPE1	viability after 18 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.451940155250784	[2350]	[385,546]	-3	hSpCas9	negative selection	1366693
40900852	40900875	15	+	26627737	RPE1	viability after 18 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.857590089073297	[719]	[113,99]	-5	hSpCas9	negative selection	1366694
40902687	40902710	15	+	26627737	RPE1	viability after 18 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.619024349820497	[1529]	[409,117]	-4	hSpCas9	negative selection	1366695
40894826	40894849	15	-	26627737	HeLa	viability after 8 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.373892397807825	[144]	[69,5,72]	-4	hSpCas9	negative selection	1449005
40896038	40896061	15	+	26627737	HeLa	viability after 8 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.6046204033615892	[416]	[368,288,195]	5	hSpCas9	negative selection	1449006
40898922	40898945	15	+	26627737	HeLa	viability after 8 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.787558936976954	[302]	[101,29,100]	-7	hSpCas9	negative selection	1449007
40898937	40898960	15	-	26627737	HeLa	viability after 8 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.1379021123324242	[1013]	[249,155,205]	-8	hSpCas9	negative selection	1449008
40900852	40900875	15	+	26627737	HeLa	viability after 8 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.0538347232923002	[315]	[30,138,23]	-8	hSpCas9	negative selection	1449009
40902687	40902710	15	+	26627737	HeLa	viability after 8 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	4.678154229184875	[9]	[122,105,107]	9	hSpCas9	negative selection	1449010
40894826	40894849	15	-	26627737	HeLa	viability after 12 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.09215947282467796	[144]	[78,77,9]	-1	hSpCas9	negative selection	1531320
40896038	40896061	15	+	26627737	HeLa	viability after 12 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-1.0267153166600655	[416]	[45,99,104]	-7	hSpCas9	negative selection	1531321
40898922	40898945	15	+	26627737	HeLa	viability after 12 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.6258189025116985	[302]	[83,30,8]	-9	hSpCas9	negative selection	1531322
40898937	40898960	15	-	26627737	HeLa	viability after 12 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.5356700643302088	[1013]	[6,206,208]	-8	hSpCas9	negative selection	1531323
40900852	40900875	15	+	26627737	HeLa	viability after 12 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.6780065799360373	[315]	[0,33,86]	-9	hSpCas9	negative selection	1531324
40902687	40902710	15	+	26627737	HeLa	viability after 12 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	4.204848692712094	[9]	[96,68,63]	9	hSpCas9	negative selection	1531325
40894826	40894849	15	-	26627737	HeLa	viability after 15 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.6091823673789536	[144]	[63,109,96]	5	hSpCas9	negative selection	1613635
40896038	40896061	15	+	26627737	HeLa	viability after 15 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.9373530216137218	[416]	[69,145,46]	-7	hSpCas9	negative selection	1613636
40898922	40898945	15	+	26627737	HeLa	viability after 15 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.1577882107476898	[302]	[28,35,104]	-7	hSpCas9	negative selection	1613637
40898937	40898960	15	-	26627737	HeLa	viability after 15 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.0296571889619281	[1013]	[184,132,295]	-7	hSpCas9	negative selection	1613638
40900852	40900875	15	+	26627737	HeLa	viability after 15 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.8465205552907955	[315]	[43,62,110]	-6	hSpCas9	negative selection	1613639
40902687	40902710	15	+	26627737	HeLa	viability after 15 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	4.316811404501477	[9]	[127,6,109]	9	hSpCas9	negative selection	1613640
40894826	40894849	15	-	26627737	HeLa	viability after 18 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.5502697730267617	[144]	[43,80,96]	4	hSpCas9	negative selection	1695950
40896038	40896061	15	+	26627737	HeLa	viability after 18 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.913136154109706	[416]	[48,121,46]	-7	hSpCas9	negative selection	1695951
40898922	40898945	15	+	26627737	HeLa	viability after 18 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.169983173196009	[302]	[15,32,104]	-8	hSpCas9	negative selection	1695952
40898937	40898960	15	-	26627737	HeLa	viability after 18 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.0341794369329722	[1013]	[122,109,295]	-7	hSpCas9	negative selection	1695953
40900852	40900875	15	+	26627737	HeLa	viability after 18 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.8554124400693444	[315]	[27,52,110]	-6	hSpCas9	negative selection	1695954
40902687	40902710	15	+	26627737	HeLa	viability after 18 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	4.234801034197234	[9]	[76,5,109]	9	hSpCas9	negative selection	1695955
40894826	40894849	15	-	26627737	HCT116	viability after 6 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-1.5914774417312838	[140]	[7,6]	-7	hSpCas9	negative selection	1778265
40896038	40896061	15	+	26627737	HCT116	viability after 6 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.49834875259039685	[467]	[130,88]	2	hSpCas9	negative selection	1778266
40898922	40898945	15	+	26627737	HCT116	viability after 6 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.16675402739808132	[386]	[37,84]	0	hSpCas9	negative selection	1778267
40898937	40898960	15	-	26627737	HCT116	viability after 6 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	2.2776186246191417	[1326]	[132,1495]	9	hSpCas9	negative selection	1778268
40900852	40900875	15	+	26627737	HCT116	viability after 6 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.2886327363853816	[537]	[42,29]	-6	hSpCas9	negative selection	1778269
40902687	40902710	15	+	26627737	HCT116	viability after 6 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	0.9490243184085705	[495]	[272,82]	5	hSpCas9	negative selection	1778270
40894826	40894849	15	-	26627737	HCT116	viability after 8 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	2.263542860097364	[36]	[115,78,98]	9	hSpCas9	negative selection	1860580
40896038	40896061	15	+	26627737	HCT116	viability after 8 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	1.5973199012697152	[123]	[134,280,202]	9	hSpCas9	negative selection	1860581
40898922	40898945	15	+	26627737	HCT116	viability after 8 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.29552390239563686	[193]	[100,110,49]	-3	hSpCas9	negative selection	1860582
40898937	40898960	15	-	26627737	HCT116	viability after 8 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.3082546122365047	[382]	[100,148,258]	-4	hSpCas9	negative selection	1860583
40900852	40900875	15	+	26627737	HCT116	viability after 8 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.6338026284324346	[161]	[52,19,98]	-6	hSpCas9	negative selection	1860584
40902687	40902710	15	+	26627737	HCT116	viability after 8 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.45037120535762204	[302]	[57,149,156]	-5	hSpCas9	negative selection	1860585
40894826	40894849	15	-	26627737	HCT116	viability after 9 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.6649450806855837	[140]	[33,79]	5	hSpCas9	negative selection	1942895
40896038	40896061	15	+	26627737	HCT116	viability after 9 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	1.6975259718863667	[467]	[263,516]	9	hSpCas9	negative selection	1942896
40898922	40898945	15	+	26627737	HCT116	viability after 9 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.5129949490823026	[386]	[77,67]	-4	hSpCas9	negative selection	1942897
40898937	40898960	15	-	26627737	HCT116	viability after 9 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.7546554359989963	[1326]	[228,194]	-5	hSpCas9	negative selection	1942898
40900852	40900875	15	+	26627737	HCT116	viability after 9 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-2.2064184222776406	[537]	[48,16]	-9	hSpCas9	negative selection	1942899
40902687	40902710	15	+	26627737	HCT116	viability after 9 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.8854321816897752	[495]	[45,91]	-6	hSpCas9	negative selection	1942900
40894826	40894849	15	-	26627737	HCT116	viability after 12 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	2.336185983151713	[36]	[95,66,130]	9	hSpCas9	negative selection	2025210
40896038	40896061	15	+	26627737	HCT116	viability after 12 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	1.9128826456132666	[123]	[166,160,412]	9	hSpCas9	negative selection	2025211
40898922	40898945	15	+	26627737	HCT116	viability after 12 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.1475629676179357	[193]	[39,62,35]	-8	hSpCas9	negative selection	2025212
40898937	40898960	15	-	26627737	HCT116	viability after 12 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.12468740906974213	[382]	[98,334,130]	-1	hSpCas9	negative selection	2025213
40900852	40900875	15	+	26627737	HCT116	viability after 12 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	0.5980552176983072	[161]	[81,57,248]	5	hSpCas9	negative selection	2025214
40902687	40902710	15	+	26627737	HCT116	viability after 12 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.2639128021080648	[302]	[88,27,78]	-8	hSpCas9	negative selection	2025215
40894826	40894849	15	-	26627737	HCT116	viability after 15 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	2.8377140384393704	[36]	[227,86,149]	9	hSpCas9	negative selection	2107525
40896038	40896061	15	+	26627737	HCT116	viability after 15 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	1.6393553565084917	[123]	[103,225,319]	9	hSpCas9	negative selection	2107526
40898922	40898945	15	+	26627737	HCT116	viability after 15 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.8110814365287344	[193]	[91,40,60]	-7	hSpCas9	negative selection	2107527
40898937	40898960	15	-	26627737	HCT116	viability after 15 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.41027117219570863	[382]	[276,141,91]	-4	hSpCas9	negative selection	2107528
40900852	40900875	15	+	26627737	HCT116	viability after 15 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.7182508504940218	[161]	[28,55,80]	-6	hSpCas9	negative selection	2107529
40902687	40902710	15	+	26627737	HCT116	viability after 15 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.83018983939471	[302]	[96,34,20]	-9	hSpCas9	negative selection	2107530
40894826	40894849	15	-	26627737	HCT116	viability after 18 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	2.8835711692887447	[36]	[147,176,64]	9	hSpCas9	negative selection	2189840
40896038	40896061	15	+	26627737	HCT116	viability after 18 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	2.110740676765038	[123]	[54,314,409]	9	hSpCas9	negative selection	2189841
40898922	40898945	15	+	26627737	HCT116	viability after 18 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.647541571091127	[193]	[12,0,79]	-8	hSpCas9	negative selection	2189842
40898937	40898960	15	-	26627737	HCT116	viability after 18 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.6699360147964544	[382]	[191,77,79]	-6	hSpCas9	negative selection	2189843
40900852	40900875	15	+	26627737	HCT116	viability after 18 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	0.16832977379679004	[161]	[75,58,132]	1	hSpCas9	negative selection	2189844
40902687	40902710	15	+	26627737	HCT116	viability after 18 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-0.6606186053487237	[302]	[87,145,37]	-6	hSpCas9	negative selection	2189845
40899388	40899411	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	-0.8429311772742945	[4,3]	[2,0]	-8	hSpCas9	positive selection	3031894
40898937	40898960	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.551022152033341	[4,4]	[2,1]	-7	hSpCas9	positive selection	3031895
40899158	40899181	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	-0.7008428265618672	[3,3]	[3,0]	-8	hSpCas9	positive selection	3031896
40899472	40899495	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	-0.4531398493570979	[4,4]	[2,2]	-6	hSpCas9	positive selection	3031897
40899388	40899411	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	-0.4615827446012001	[4,4]	[2,1]	-6	hSpCas9	positive selection	3099752
40898937	40898960	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.4071693100337685	[4,4]	[3,0]	-6	hSpCas9	positive selection	3099753
40899158	40899181	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	-0.7827851318189716	[3,3]	[2,0]	-9	hSpCas9	positive selection	3099754
40899472	40899495	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	-0.8448031327833433	[4,4]	[1,0]	-9	hSpCas9	positive selection	3099755
40896019	40896042		-	24336571	A375	resistance to PLX after 7 days	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	0.418058188520564	[5,6]	[8,8]	9	hSpCas9	positive selection	3155074
40896038	40896061		+	24336571	A375	resistance to PLX after 7 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.00903200002556967	[11,10]	[11,10]	0	hSpCas9	positive selection	3155076
40898922	40898945		+	24336571	A375	resistance to PLX after 7 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.16280324728514528	[4,7]	[6,6]	5	hSpCas9	positive selection	3155077
40898985	40899008		-	24336571	A375	resistance to PLX after 7 days	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	0.21999639860564874	[8,9]	[8,11]	6	hSpCas9	positive selection	3155078
40896019	40896042		-	24336571	A375	resistance to PLX after 14 days	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	0.8309933530677535	[3,3]	[3,1]	7	hSpCas9	positive selection	3212867
40896038	40896061		+	24336571	A375	resistance to PLX after 14 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.1286806990598231	[8,12]	[5,3]	1	hSpCas9	positive selection	3212869
40898922	40898945		+	24336571	A375	resistance to PLX after 14 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.4326673839451304	[3,5]	[1,2]	4	hSpCas9	positive selection	3212870
40898985	40899008		-	24336571	A375	resistance to PLX after 14 days	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	1.009665115332444	[4,5]	[5,3]	7	hSpCas9	positive selection	3212871
40896019	40896042		-	24336571	A375	viability after 7 days	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	-0.47935266338357946	[9]	[5,6]	-6	hSpCas9	negative selection	3270660
40896038	40896061		+	24336571	A375	viability after 7 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.10667385422368704	[12]	[11,10]	-1	hSpCas9	negative selection	3270662
40898922	40898945		+	24336571	A375	viability after 7 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.4162776931514759	[8]	[4,7]	-5	hSpCas9	negative selection	3270663
40898985	40899008		-	24336571	A375	viability after 7 days	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	-0.43742831523661035	[12]	[8,9]	-6	hSpCas9	negative selection	3270664
40896019	40896042		-	24336571	A375	viability after 14 days	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	-1.1210562361130239	[9]	[3,3]	-8	hSpCas9	negative selection	3328453
40896038	40896061		+	24336571	A375	viability after 14 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.2076026157540214	[12]	[8,12]	-2	hSpCas9	negative selection	3328455
40898922	40898945		+	24336571	A375	viability after 14 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.7559573083903252	[8]	[3,5]	-7	hSpCas9	negative selection	3328456
40898985	40899008		-	24336571	A375	viability after 14 days	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	-1.1786410741674946	[12]	[4,5]	-9	hSpCas9	negative selection	3328457
40900906	40900929	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	1.449971289388231	[55,55]	[0,0]	6	hSpCas9	positive selection	3400978
40898922	40898945	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3400979
40898977	40899000	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	4.087401210003523	[8,8]	[0,0]	9	hSpCas9	positive selection	3400980
40899388	40899411	15	-	26780180	HT29	viability (Avana library 4 designs)	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	3.37493054046437	[]	[]	8	hSpCas9	negative selection	3471126
40898937	40898960	15	-	26780180	HT29	viability (Avana library 4 designs)	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	2.7652950898166	[]	[]	8	hSpCas9	negative selection	3471127
40899157	40899180	15	+	26780180	HT29	viability (Avana library 4 designs)	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	5.9327828098486	[]	[]	9	hSpCas9	negative selection	3471128
40899471	40899494	15	+	26780180	HT29	viability (Avana library 4 designs)	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	2.85566205034962	[]	[]	8	hSpCas9	negative selection	3471129
40898937	40898960	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-13.4768017438024	[]	[]	-8	hSpCas9	negative selection	3577777
40899471	40899494	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	4.36260815601151	[]	[]	7	hSpCas9	negative selection	3577778
40899157	40899180	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	-9.84370095311275	[]	[]	-7	hSpCas9	negative selection	3577779
40899388	40899411	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	-6.90002912780653	[]	[]	-6	hSpCas9	negative selection	3577780
40899154	40899177	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGATTGCCCTGAGCAGCACGG	VPS18	ENSG00000104142	-6.25363063842793	[]	[]	-6	hSpCas9	negative selection	3577781
40899826	40899849	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-4.01388229441492	[]	[]	-4	hSpCas9	negative selection	3577782
40898937	40898960	15	-	26780180	A375	viability (Avana lentiGuide)	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	17.3542239646257	[]	[]	8	hSpCas9	negative selection	3686436
40899471	40899494	15	+	26780180	A375	viability (Avana lentiGuide)	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	15.2531374109605	[]	[]	8	hSpCas9	negative selection	3686437
40899157	40899180	15	+	26780180	A375	viability (Avana lentiGuide)	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	22.801582194226	[]	[]	9	hSpCas9	negative selection	3686438
40899388	40899411	15	-	26780180	A375	viability (Avana lentiGuide)	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	18.3952304607332	[]	[]	8	hSpCas9	negative selection	3686439
40899154	40899177	15	+	26780180	A375	viability (Avana lentiGuide)	GCTGATTGCCCTGAGCAGCACGG	VPS18	ENSG00000104142	14.1352039676396	[]	[]	8	hSpCas9	negative selection	3686440
40899826	40899849	15	+	26780180	A375	viability (Avana lentiGuide)	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	22.2831266126769	[]	[]	9	hSpCas9	negative selection	3686441
40898937	40898960	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.6021654044068383	[5]	[3,2]	-7	hSpCas9	positive selection	3795043
40899471	40899494	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	0.16911209016299256	[5]	[6,5]	4	hSpCas9	positive selection	3795044
40899157	40899180	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	-0.15785172062233244	[5]	[5,4]	-3	hSpCas9	positive selection	3795045
40899388	40899411	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	0.01560581741586245	[6]	[6,5]	0	hSpCas9	positive selection	3795046
40899154	40899177	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGATTGCCCTGAGCAGCACGG	VPS18	ENSG00000104142	0.02044731224515181	[5]	[6,4]	0	hSpCas9	positive selection	3795047
40899826	40899849	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.13797223466522607	[3]	[3,1]	-2	hSpCas9	positive selection	3795048
40898937	40898960	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-0.09013878739441358	[6]	[4,5]	-1	hSpCas9	positive selection	3903650
40899471	40899494	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTTGTTATTGCCACCACTCGG	VPS18	ENSG00000104142	-0.6256199049987005	[6]	[3,2]	-7	hSpCas9	positive selection	3903651
40899157	40899180	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGCCCTGAGCAGCACGGAGG	VPS18	ENSG00000104142	-1.298136760247818	[6]	[1,1]	-9	hSpCas9	positive selection	3903652
40899388	40899411	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTTAGCACGTACAATGGGCGG	VPS18	ENSG00000104142	-0.21495054419731102	[6]	[4,4]	-3	hSpCas9	positive selection	3903653
40899154	40899177	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGATTGCCCTGAGCAGCACGG	VPS18	ENSG00000104142	-0.2163553820253128	[5]	[3,4]	-3	hSpCas9	positive selection	3903654
40899826	40899849	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-1.6133823825813236	[3]	[0,0]	-9	hSpCas9	positive selection	3903655
40898977	40899000	15	+	26780180	A375	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.685042776755622	[]	[]	2	hSpCas9	negative selection	4011716
40900906	40900929	15	-	26780180	A375	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	1.76002155118103	[]	[]	9	hSpCas9	negative selection	4011717
40903296	40903319	15	+	26780180	A375	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.515701394406316	[]	[]	1	hSpCas9	negative selection	4011718
40898922	40898945	15	+	26780180	A375	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	1.37064515478377	[]	[]	7	hSpCas9	negative selection	4011719
40899179	40899202	15	+	26780180	A375	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.284256084570028	[]	[]	0	hSpCas9	negative selection	4011720
40903268	40903291	15	+	26780180	A375	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	2.62506796489689	[]	[]	9	hSpCas9	negative selection	4011721
40898977	40899000	15	+	26780180	HT29	viability (GeCKOv2 library)	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	1.10342851454807	[]	[]	5	hSpCas9	negative selection	4119682
40900906	40900929	15	-	26780180	HT29	viability (GeCKOv2 library)	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	1.36975391071916	[]	[]	7	hSpCas9	negative selection	4119683
40903296	40903319	15	+	26780180	HT29	viability (GeCKOv2 library)	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	1.22962923514622	[]	[]	6	hSpCas9	negative selection	4119684
40898922	40898945	15	+	26780180	HT29	viability (GeCKOv2 library)	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	1.59798687816429	[]	[]	8	hSpCas9	negative selection	4119685
40899179	40899202	15	+	26780180	HT29	viability (GeCKOv2 library)	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.478901017085296	[]	[]	1	hSpCas9	negative selection	4119686
40903268	40903291	15	+	26780180	HT29	viability (GeCKOv2 library)	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	3.44088124316377	[]	[]	9	hSpCas9	negative selection	4119687
40896019	40896042	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	-0.27152225939021346	[2]	[1,1]	-6	hSpCas9	positive selection	4181826
40896038	40896061	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.051310040837239515	[3]	[1,2]	-1	hSpCas9	positive selection	4181828
40898922	40898945	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.18590688061250035	[3]	[1,1]	-4	hSpCas9	positive selection	4181829
40898985	40899008	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	-0.04795447128763179	[3]	[2,2]	-1	hSpCas9	positive selection	4181830
40896019	40896042	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTGCTGGAGACGACAAGACTGG	VPS18	ENSG00000104142	-0.34532201204585256	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4245848
40896038	40896061	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.2140693113305115	[2]	[1,0,0,0]	-3	hSpCas9	positive selection	4245850
40898922	40898945	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	1.4279287440412491	[2]	[0,2,2,4]	9	hSpCas9	positive selection	4245851
40898985	40899008	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACTTACCAGTATGGTCAAGG	VPS18	ENSG00000104142	0.9230351720066435	[3]	[0,0,2,3]	6	hSpCas9	positive selection	4245852
40903268	40903291	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.655737304800675	[3]	[2,0]	-9	hSpCas9	positive selection	4307363
40899179	40899202	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.45349976179189866	[1]	[1,1]	8	hSpCas9	positive selection	4307364
40903296	40903319	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.0014442931839551872	[2]	[2,1]	0	hSpCas9	positive selection	4307365
40900906	40900929	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.46373616425893727	[2]	[1,0]	-7	hSpCas9	positive selection	4371611
40898922	40898945	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.1380050716039164	[2]	[3,0]	-3	hSpCas9	positive selection	4371612
40898977	40899000	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.27641109485645876	[1]	[1,0]	5	hSpCas9	positive selection	4371613
40896003	40896025	15	-	27760321	OCIAML3	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.27113653885682	[973,832]	[571,598]	-3	hSpCas9	negative selection	4453381
40899208	40899230	15	+	27760321	OCIAML3	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.1986415322609092	[833,775]	[299,240]	-8	hSpCas9	negative selection	4453382
40899980	40900002	15	+	27760321	OCIAML3	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.0305309270103236	[762,672]	[210,356]	-7	hSpCas9	negative selection	4453383
40900028	40900050	15	+	27760321	OCIAML3	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.0278308403147096	[591,528]	[248,169]	-7	hSpCas9	negative selection	4453384
40900118	40900140	15	+	27760321	OCIAML3	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.4051205718959519	[435,373]	[211,272]	-4	hSpCas9	negative selection	4453385
40896003	40896025	15	-	27760321	OCIAML2	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.7509865022717566	[973,832]	[378,503]	-7	hSpCas9	negative selection	4536844
40899208	40899230	15	+	27760321	OCIAML2	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-0.789930572116619	[833,775]	[368,386]	-7	hSpCas9	negative selection	4536845
40899980	40900002	15	+	27760321	OCIAML2	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-0.9482665481304486	[762,672]	[274,333]	-7	hSpCas9	negative selection	4536846
40900028	40900050	15	+	27760321	OCIAML2	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.119309743471433	[591,528]	[185,237]	-8	hSpCas9	negative selection	4536847
40900118	40900140	15	+	27760321	OCIAML2	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.5679736504578031	[435,373]	[190,258]	-6	hSpCas9	negative selection	4536848
40896003	40896025	15	-	27760321	MV411	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.47453041915468464	[973,832]	[380,497]	-3	hSpCas9	negative selection	4620307
40899208	40899230	15	+	27760321	MV411	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	0.0600308798264827	[833,775]	[278,966]	0	hSpCas9	negative selection	4620308
40899980	40900002	15	+	27760321	MV411	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	0.9988554803044232	[762,672]	[829,1117]	7	hSpCas9	negative selection	4620309
40900028	40900050	15	+	27760321	MV411	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-0.9206737408660284	[591,528]	[111,319]	-6	hSpCas9	negative selection	4620310
40900118	40900140	15	+	27760321	MV411	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.7425827612649698	[435,373]	[223,61]	-5	hSpCas9	negative selection	4620311
40896003	40896025	15	-	27760321	HL60	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.7412225793397618	[973,832]	[328,557]	-6	hSpCas9	negative selection	4703770
40899208	40899230	15	+	27760321	HL60	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-0.21365383372702718	[833,775]	[525,610]	-2	hSpCas9	negative selection	4703771
40899980	40900002	15	+	27760321	HL60	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	0.342215389754694	[762,672]	[862,613]	4	hSpCas9	negative selection	4703772
40900028	40900050	15	+	27760321	HL60	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.5479240210839338	[591,528]	[168,142]	-8	hSpCas9	negative selection	4703773
40900118	40900140	15	+	27760321	HL60	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.2536385355664238	[435,373]	[248,305]	-3	hSpCas9	negative selection	4703774
40896003	40896025	15	-	27760321	HT1080	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.8074641849330162	[832,649]	[60,109]	-6	hSpCas9	negative selection	4787233
40899208	40899230	15	+	27760321	HT1080	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-3.651528832283764	[775,605]	[40,0]	-7	hSpCas9	negative selection	4787234
40899980	40900002	15	+	27760321	HT1080	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.8238606914374198	[672,524]	[117,11]	-6	hSpCas9	negative selection	4787235
40900028	40900050	15	+	27760321	HT1080	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-3.329762024755493	[528,412]	[0,37]	-7	hSpCas9	negative selection	4787236
40900118	40900140	15	+	27760321	HT1080	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-2.9852796754903217	[373,291]	[0,33]	-7	hSpCas9	negative selection	4787237
40896003	40896025	15	-	27760321	HT29	viability after 7 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.6177235925841917	[832,649]	[816,805,278]	-7	hSpCas9	negative selection	4870696
40899208	40899230	15	+	27760321	HT29	viability after 7 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-0.3219658216125134	[775,605]	[429,721,931]	-4	hSpCas9	negative selection	4870697
40899980	40900002	15	+	27760321	HT29	viability after 7 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-0.030891370040019295	[672,524]	[891,410,969]	0	hSpCas9	negative selection	4870698
40900028	40900050	15	+	27760321	HT29	viability after 7 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-0.7272638426533073	[528,412]	[359,336,397]	-7	hSpCas9	negative selection	4870699
40900118	40900140	15	+	27760321	HT29	viability after 7 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-1.2585106461937883	[373,291]	[175,206,153]	-9	hSpCas9	negative selection	4870700
40896003	40896025	15	-	27760321	HT29	viability after 25 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.8000716829889258	[832,649]	[298,184,241]	-8	hSpCas9	negative selection	4954159
40899208	40899230	15	+	27760321	HT29	viability after 25 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.9865018408000301	[775,605]	[355,89,134]	-8	hSpCas9	negative selection	4954160
40899980	40900002	15	+	27760321	HT29	viability after 25 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.583999699213071	[672,524]	[122,169,417]	-7	hSpCas9	negative selection	4954161
40900028	40900050	15	+	27760321	HT29	viability after 25 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.3384393014383889	[528,412]	[206,206,225]	-7	hSpCas9	negative selection	4954162
40900118	40900140	15	+	27760321	HT29	viability after 25 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-1.6538394446412323	[373,291]	[154,62,144]	-7	hSpCas9	negative selection	4954163
40896003	40896025	15	-	27760321	HT29	viability after 22 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.6992072772677007	[832,649]	[160,443,188]	-8	hSpCas9	negative selection	5037622
40899208	40899230	15	+	27760321	HT29	viability after 22 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.9766683021296383	[775,605]	[317,167,118]	-8	hSpCas9	negative selection	5037623
40899980	40900002	15	+	27760321	HT29	viability after 22 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.2197347752910916	[672,524]	[341,221,326]	-7	hSpCas9	negative selection	5037624
40900028	40900050	15	+	27760321	HT29	viability after 22 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.699346464272945	[528,412]	[202,135,162]	-8	hSpCas9	negative selection	5037625
40900118	40900140	15	+	27760321	HT29	viability after 22 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-2.5723299992880513	[373,291]	[63,85,43]	-8	hSpCas9	negative selection	5037626
40896003	40896025	15	-	27760321	HT29	viability after 19 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.1387874234356592	[832,649]	[277,295,562]	-7	hSpCas9	negative selection	5121085
40899208	40899230	15	+	27760321	HT29	viability after 19 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-3.038574354080554	[775,605]	[231,62,10]	-8	hSpCas9	negative selection	5121086
40899980	40900002	15	+	27760321	HT29	viability after 19 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.6500737297070944	[672,524]	[288,152,219]	-7	hSpCas9	negative selection	5121087
40900028	40900050	15	+	27760321	HT29	viability after 19 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.66719469633302	[528,412]	[220,93,197]	-7	hSpCas9	negative selection	5121088
40900118	40900140	15	+	27760321	HT29	viability after 19 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-2.87603550096922	[373,291]	[108,11,40]	-8	hSpCas9	negative selection	5121089
40896003	40896025	15	-	27760321	HT29	viability after 16 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.2490763496529622	[832,649]	[395,365,288]	-7	hSpCas9	negative selection	5204548
40899208	40899230	15	+	27760321	HT29	viability after 16 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.8624115389160045	[775,605]	[236,255,145]	-8	hSpCas9	negative selection	5204549
40899980	40900002	15	+	27760321	HT29	viability after 16 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.8642671620979971	[672,524]	[177,129,244]	-8	hSpCas9	negative selection	5204550
40900028	40900050	15	+	27760321	HT29	viability after 16 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.4611247987007843	[528,412]	[112,143,310]	-8	hSpCas9	negative selection	5204551
40900118	40900140	15	+	27760321	HT29	viability after 16 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-1.0472144147489306	[373,291]	[192,104,245]	-7	hSpCas9	negative selection	5204552
40896003	40896025	15	-	27760321	HT29	viability after 13 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-0.7333680940794025	[832,649]	[788,440,332]	-6	hSpCas9	negative selection	5288011
40899208	40899230	15	+	27760321	HT29	viability after 13 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.2296554404284423	[775,605]	[223,361,433]	-8	hSpCas9	negative selection	5288012
40899980	40900002	15	+	27760321	HT29	viability after 13 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.3301189184322368	[672,524]	[270,262,293]	-8	hSpCas9	negative selection	5288013
40900028	40900050	15	+	27760321	HT29	viability after 13 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.027630073977175	[528,412]	[326,346,137]	-7	hSpCas9	negative selection	5288014
40900118	40900140	15	+	27760321	HT29	viability after 13 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-1.6244648393846646	[373,291]	[180,90,104]	-8	hSpCas9	negative selection	5288015
40896003	40896025	15	-	27760321	HT29	viability after 10 days	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.0040470562409003	[832,649]	[515,522,349]	-8	hSpCas9	negative selection	5371474
40899208	40899230	15	+	27760321	HT29	viability after 10 days	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-1.245264055686322	[775,605]	[326,484,284]	-8	hSpCas9	negative selection	5371475
40899980	40900002	15	+	27760321	HT29	viability after 10 days	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-0.7716238951333466	[672,524]	[265,271,763]	-7	hSpCas9	negative selection	5371476
40900028	40900050	15	+	27760321	HT29	viability after 10 days	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-1.4080337157872589	[528,412]	[234,159,266]	-8	hSpCas9	negative selection	5371477
40900118	40900140	15	+	27760321	HT29	viability after 10 days	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.9039785462400023	[373,291]	[141,246,276]	-7	hSpCas9	negative selection	5371478
40896003	40896025	15	-	27760321	MOLM13	viability	GACTGGTAATGCGCTCGGAAGG	VPS18	ENSG00000104142	-1.8133078314048454	[973,832]	[176,116]	-7	hSpCas9	negative selection	5454937
40899208	40899230	15	+	27760321	MOLM13	viability	GGTACGGCCACTAGCACGCTGG	VPS18	ENSG00000104142	-0.67572394904214	[833,775]	[298,271]	-4	hSpCas9	negative selection	5454938
40899980	40900002	15	+	27760321	MOLM13	viability	CGCTACCACGTGCAACGGGAGG	VPS18	ENSG00000104142	-1.58472813830155	[762,672]	[197,80]	-7	hSpCas9	negative selection	5454939
40900028	40900050	15	+	27760321	MOLM13	viability	GACATGAACCGCTTCGATCTGG	VPS18	ENSG00000104142	-4.328121537231323	[591,528]	[5,23]	-9	hSpCas9	negative selection	5454940
40900118	40900140	15	+	27760321	MOLM13	viability	TTTCGCCAGCGTCGCTACCTGG	VPS18	ENSG00000104142	-0.19977989749366382	[435,373]	[354,64]	-1	hSpCas9	negative selection	5454941
40894466	40894489	15	+	27661255	K562	viability	GGGGCGAGGTTGGGATCACCTGG	VPS18	ENSG00000104142	-0.15596246550420556	[640,616]	[521,390]	-5	dCas9-KRAB	negative selection	5522265
40903268	40903291	15	+	27260156	BXPC3	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.36784124587157563	[821]	[679,616,667,699]	-7	hSpCas9	negative selection	5579823
40899179	40899202	15	+	27260156	BXPC3	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.43887042722297953	[96]	[83,164,139,167]	8	hSpCas9	negative selection	5579824
40903296	40903319	15	+	27260156	BXPC3	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.22198124460357316	[437]	[448,466,550,699]	5	hSpCas9	negative selection	5579825
40900906	40900929	15	-	27260156	BXPC3	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.4542858353244785	[291]	[164,197,207,340]	-7	hSpCas9	negative selection	5644071
40898922	40898945	15	+	27260156	BXPC3	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.255331531445917	[420]	[351,373,339,412]	-5	hSpCas9	negative selection	5644072
40898977	40899000	15	+	27260156	BXPC3	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.033938323376569546	[78]	[81,85,101,47]	0	hSpCas9	negative selection	5644073
40903268	40903291	15	+	27260156	A673	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.26552970714565904	[821]	[1008,929,660,695]	-6	hSpCas9	negative selection	5701074
40899179	40899202	15	+	27260156	A673	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.19209359359679867	[96]	[136,93,126,177]	4	hSpCas9	negative selection	5701075
40903296	40903319	15	+	27260156	A673	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.4043452184740086	[437]	[704,640,652,791]	8	hSpCas9	negative selection	5701076
40900906	40900929	15	-	27260156	A673	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.4162849206123267	[291]	[223,306,190,326]	-8	hSpCas9	negative selection	5765322
40898922	40898945	15	+	27260156	A673	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.27195328638468647	[420]	[413,422,448,384]	-6	hSpCas9	negative selection	5765323
40898977	40899000	15	+	27260156	A673	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.1927406637049125	[78]	[47,100,97,79]	-5	hSpCas9	negative selection	5765324
40903268	40903291	15	+	27260156	A375	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.12360645906797962	[821]	[921,791,872,917]	-2	hSpCas9	negative selection	5822325
40899179	40899202	15	+	27260156	A375	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.1070712602130186	[96]	[150,157,68,55]	-1	hSpCas9	negative selection	5822326
40903296	40903319	15	+	27260156	A375	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.15433312010296862	[437]	[513,335,459,892]	2	hSpCas9	negative selection	5822327
40900906	40900929	15	-	27260156	A375	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.981551930859373	[291]	[208,255,146,98]	-8	hSpCas9	negative selection	5886573
40898922	40898945	15	+	27260156	A375	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.9842781177380509	[420]	[229,280,259,228]	-8	hSpCas9	negative selection	5886574
40898977	40899000	15	+	27260156	A375	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.03474116701145302	[78]	[73,246,19,45]	0	hSpCas9	negative selection	5886575
40903268	40903291	15	+	27260156	COLO741	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.12584319942188282	[821]	[941,870,1062]	-3	hSpCas9	negative selection	5943576
40899179	40899202	15	+	27260156	COLO741	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.10408698696260776	[96]	[126,178,45]	-2	hSpCas9	negative selection	5943577
40903296	40903319	15	+	27260156	COLO741	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.3165010562723789	[437]	[815,710,580]	6	hSpCas9	negative selection	5943578
40900906	40900929	15	-	27260156	COLO741	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	0.021493259052537184	[291]	[386,273,467]	0	hSpCas9	negative selection	6007824
40898922	40898945	15	+	27260156	COLO741	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.44088550209912686	[420]	[348,340,486]	-7	hSpCas9	negative selection	6007825
40898977	40899000	15	+	27260156	COLO741	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.2863670960622944	[78]	[85,240,44]	6	hSpCas9	negative selection	6007826
40903268	40903291	15	+	27260156	CAL120	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.027374057164399224	[821]	[1205,774,1058]	0	hSpCas9	negative selection	6064827
40899179	40899202	15	+	27260156	CAL120	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.8591354005656062	[96]	[487,143,67]	9	hSpCas9	negative selection	6064828
40903296	40903319	15	+	27260156	CAL120	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.11800787395646256	[437]	[604,619,551]	1	hSpCas9	negative selection	6064829
40900906	40900929	15	-	27260156	CAL120	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.4302376918194148	[291]	[172,147,89]	-9	hSpCas9	negative selection	6129075
40898922	40898945	15	+	27260156	CAL120	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.8261638788286603	[420]	[450,233,225]	-8	hSpCas9	negative selection	6129076
40898977	40899000	15	+	27260156	CAL120	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.11988007016842017	[78]	[56,96,157]	1	hSpCas9	negative selection	6129077
40903268	40903291	15	+	27260156	CADOES1	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.23723099180534446	[821]	[765,549,548,731]	-4	hSpCas9	negative selection	6186078
40899179	40899202	15	+	27260156	CADOES1	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.49788265018358424	[96]	[80,184,162,78]	7	hSpCas9	negative selection	6186079
40903296	40903319	15	+	27260156	CADOES1	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.11114696908191647	[437]	[547,344,438,426]	2	hSpCas9	negative selection	6186080
40900906	40900929	15	-	27260156	CADOES1	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.43935561537328827	[291]	[177,255,148,218]	-6	hSpCas9	negative selection	6250326
40898922	40898945	15	+	27260156	CADOES1	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6220896889580636	[420]	[247,222,229,318]	-8	hSpCas9	negative selection	6250327
40898977	40899000	15	+	27260156	CADOES1	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.4786747931876998	[78]	[40,90,26,51]	-7	hSpCas9	negative selection	6250328
40903268	40903291	15	+	27260156	EWS502	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.16378640487011753	[821]	[708,831,762,809]	-3	hSpCas9	negative selection	6307329
40899179	40899202	15	+	27260156	EWS502	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.4111060366386825	[96]	[129,134,159,120]	7	hSpCas9	negative selection	6307330
40903296	40903319	15	+	27260156	EWS502	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.25210693029776393	[437]	[569,553,405,682]	4	hSpCas9	negative selection	6307331
40900906	40900929	15	-	27260156	EWS502	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.5970894461868521	[291]	[227,190,199,194]	-7	hSpCas9	negative selection	6371577
40898922	40898945	15	+	27260156	EWS502	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.26919216484286174	[420]	[372,386,334,382]	-5	hSpCas9	negative selection	6371578
40898977	40899000	15	+	27260156	EWS502	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.1703092918872522	[78]	[88,63,173,48]	3	hSpCas9	negative selection	6371579
40903268	40903291	15	+	27260156	EW8	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.5066067445399992	[821]	[529,564,413,381]	-7	hSpCas9	negative selection	6428580
40899179	40899202	15	+	27260156	EW8	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.7944418199780479	[96]	[263,100,94,105]	9	hSpCas9	negative selection	6428581
40903296	40903319	15	+	27260156	EW8	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	-0.06777571942671293	[437]	[364,409,303,283]	-1	hSpCas9	negative selection	6428582
40900906	40900929	15	-	27260156	EW8	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.0793269076510323	[291]	[160,68,92,132]	-9	hSpCas9	negative selection	6492828
40898922	40898945	15	+	27260156	EW8	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.2945787390432277	[420]	[177,330,307,278]	-5	hSpCas9	negative selection	6492829
40898977	40899000	15	+	27260156	EW8	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.02121788408934977	[78]	[119,98,35,15]	0	hSpCas9	negative selection	6492830
40903268	40903291	15	+	27260156	CORL105	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.06522311161886807	[821]	[1040,1073,850,703]	-1	hSpCas9	negative selection	6549831
40899179	40899202	15	+	27260156	CORL105	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.5146892136383259	[96]	[141,52,49,70]	-7	hSpCas9	negative selection	6549832
40903296	40903319	15	+	27260156	CORL105	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.5271522578104597	[437]	[733,724,860,654]	8	hSpCas9	negative selection	6549833
40900906	40900929	15	-	27260156	CORL105	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.073557120293439	[291]	[168,155,149,172]	-9	hSpCas9	negative selection	6614079
40898922	40898945	15	+	27260156	CORL105	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6161066683807761	[420]	[243,338,359,345]	-8	hSpCas9	negative selection	6614080
40898977	40899000	15	+	27260156	CORL105	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.7872752508792318	[78]	[22,49,70,71]	-8	hSpCas9	negative selection	6614081
40903268	40903291	15	+	27260156	HS294T	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.2889454775383251	[821]	[168,256,370,249]	-4	hSpCas9	negative selection	6671082
40899179	40899202	15	+	27260156	HS294T	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-1.0873331065139196	[96]	[21,17,12,16]	-9	hSpCas9	negative selection	6671083
40903296	40903319	15	+	27260156	HS294T	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.5970266339694279	[437]	[244,188,232,380]	7	hSpCas9	negative selection	6671084
40900906	40900929	15	-	27260156	HS294T	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.17154215209622525	[291]	[46,161,127,59]	-2	hSpCas9	negative selection	6735330
40898922	40898945	15	+	27260156	HS294T	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6411898274262557	[420]	[83,81,123,134]	-7	hSpCas9	negative selection	6735331
40898977	40899000	15	+	27260156	HS294T	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.33032347435435616	[78]	[23,40,14,14]	-5	hSpCas9	negative selection	6735332
40903268	40903291	15	+	27260156	HCC44	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.652757266472241	[821]	[780,518,740,379]	-7	hSpCas9	negative selection	6792333
40899179	40899202	15	+	27260156	HCC44	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.2796022326825818	[96]	[189,104,160,90]	4	hSpCas9	negative selection	6792334
40903296	40903319	15	+	27260156	HCC44	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	-0.08485328239576373	[437]	[498,413,511,457]	-1	hSpCas9	negative selection	6792335
40900906	40900929	15	-	27260156	HCC44	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.136656586688119	[291]	[430,111,46,26]	-8	hSpCas9	negative selection	6856581
40898922	40898945	15	+	27260156	HCC44	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.0641500988980828	[420]	[147,223,338,210]	-8	hSpCas9	negative selection	6856582
40898977	40899000	15	+	27260156	HCC44	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.717782160989588	[78]	[85,96,48,332]	9	hSpCas9	negative selection	6856583
40903268	40903291	15	+	27260156	G402	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.3338668639292201	[821]	[935,843,539,878]	-4	hSpCas9	negative selection	6913584
40899179	40899202	15	+	27260156	G402	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.7289626315157207	[96]	[60,501,18,199]	8	hSpCas9	negative selection	6913585
40903296	40903319	15	+	27260156	G402	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.7677818910848397	[437]	[711,717,649,1487]	8	hSpCas9	negative selection	6913586
40900906	40900929	15	-	27260156	G402	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-2.5827511555536784	[291]	[97,87,22,36]	-9	hSpCas9	negative selection	6977832
40898922	40898945	15	+	27260156	G402	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.0757883148925094	[420]	[391,209,309,88]	-8	hSpCas9	negative selection	6977833
40898977	40899000	15	+	27260156	G402	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.33614953566796224	[78]	[61,51,160,28]	-4	hSpCas9	negative selection	6977834
40903268	40903291	15	+	27260156	L33	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.1287953608570347	[821]	[809,315,445,714]	-3	hSpCas9	negative selection	7034835
40899179	40899202	15	+	27260156	L33	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.30064291322908643	[96]	[56,59,49,32]	-6	hSpCas9	negative selection	7034836
40903296	40903319	15	+	27260156	L33	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.623746479238569	[437]	[903,233,385,604]	9	hSpCas9	negative selection	7034837
40900906	40900929	15	-	27260156	L33	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.13908382727445856	[291]	[306,96,112,334]	-3	hSpCas9	negative selection	7099083
40898922	40898945	15	+	27260156	L33	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.2033025482056604	[420]	[373,174,215,317]	-5	hSpCas9	negative selection	7099084
40898977	40899000	15	+	27260156	L33	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.3330039065477255	[78]	[38,50,42,19]	-7	hSpCas9	negative selection	7099085
40903268	40903291	15	+	27260156	K562	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.49768369554199554	[821]	[670,536,484,398]	-5	hSpCas9	negative selection	7156086
40899179	40899202	15	+	27260156	K562	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-1.1734492645662575	[96]	[39,9,51,47]	-8	hSpCas9	negative selection	7156087
40903296	40903319	15	+	27260156	K562	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.09514832875719852	[437]	[778,282,375,261]	1	hSpCas9	negative selection	7156088
40900906	40900929	15	-	27260156	K562	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-2.5166656941965764	[291]	[42,94,24,22]	-9	hSpCas9	negative selection	7220334
40898922	40898945	15	+	27260156	K562	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.5364983850100395	[420]	[341,216,207,265]	-6	hSpCas9	negative selection	7220335
40898977	40899000	15	+	27260156	K562	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.555277539317387	[78]	[83,53,55,4]	-6	hSpCas9	negative selection	7220336
40903268	40903291	15	+	27260156	HT29	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.20382593986158004	[821]	[907,833,807,908]	-4	hSpCas9	negative selection	7277337
40899179	40899202	15	+	27260156	HT29	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.17992224523227263	[96]	[199,135,161,50]	3	hSpCas9	negative selection	7277338
40903296	40903319	15	+	27260156	HT29	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.3910411100371691	[437]	[771,711,669,646]	7	hSpCas9	negative selection	7277339
40900906	40900929	15	-	27260156	HT29	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.8102531419266019	[291]	[204,197,264,146]	-8	hSpCas9	negative selection	7341585
40898922	40898945	15	+	27260156	HT29	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.45918777971143404	[420]	[307,446,460,282]	-7	hSpCas9	negative selection	7341586
40898977	40899000	15	+	27260156	HT29	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.31368847245083575	[78]	[174,95,89,117]	6	hSpCas9	negative selection	7341587
40903268	40903291	15	+	27260156	MHHES1	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.3870695656743183	[821]	[812,812,906,383]	-6	hSpCas9	negative selection	7398588
40899179	40899202	15	+	27260156	MHHES1	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.31862070435529244	[96]	[53,84,70,124]	-5	hSpCas9	negative selection	7398589
40903296	40903319	15	+	27260156	MHHES1	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	-0.16458406912156331	[437]	[496,494,385,394]	-3	hSpCas9	negative selection	7398590
40900906	40900929	15	-	27260156	MHHES1	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.229057117679929	[291]	[144,249,104,82]	-9	hSpCas9	negative selection	7462836
40898922	40898945	15	+	27260156	MHHES1	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.833401487010996	[420]	[346,263,279,193]	-9	hSpCas9	negative selection	7462837
40898977	40899000	15	+	27260156	MHHES1	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-1.014698029559153	[78]	[46,42,79,12]	-9	hSpCas9	negative selection	7462838
40903268	40903291	15	+	27260156	MEWO	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	0.023402510431118184	[821]	[1058,656,682]	0	hSpCas9	negative selection	7519839
40899179	40899202	15	+	27260156	MEWO	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.4733796146626639	[96]	[150,83,147]	8	hSpCas9	negative selection	7519840
40903296	40903319	15	+	27260156	MEWO	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.18715408134494776	[437]	[535,458,417]	4	hSpCas9	negative selection	7519841
40900906	40900929	15	-	27260156	MEWO	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.2779854992971509	[291]	[246,239,192]	-6	hSpCas9	negative selection	7584087
40898922	40898945	15	+	27260156	MEWO	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.30171990209922306	[420]	[243,302,396]	-6	hSpCas9	negative selection	7584088
40898977	40899000	15	+	27260156	MEWO	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.07918174907450304	[78]	[55,103,46]	-2	hSpCas9	negative selection	7584089
40903268	40903291	15	+	27260156	LNCAPCLONEFGC	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.16403100325488096	[821]	[606,619,866,597]	-3	hSpCas9	negative selection	7641090
40899179	40899202	15	+	27260156	LNCAPCLONEFGC	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.20438777487248538	[96]	[76,80,91,56]	-3	hSpCas9	negative selection	7641091
40903296	40903319	15	+	27260156	LNCAPCLONEFGC	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.5761743229085233	[437]	[669,459,726,535]	8	hSpCas9	negative selection	7641092
40900906	40900929	15	-	27260156	LNCAPCLONEFGC	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.0833712679661136	[291]	[146,143,127,78]	-9	hSpCas9	negative selection	7705338
40898922	40898945	15	+	27260156	LNCAPCLONEFGC	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.0358820661930794	[420]	[183,206,195,156]	-9	hSpCas9	negative selection	7705339
40898977	40899000	15	+	27260156	LNCAPCLONEFGC	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.0027650739779447875	[78]	[123,24,32,99]	0	hSpCas9	negative selection	7705340
40903268	40903291	15	+	27260156	PANC0327	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.20414609726302746	[821]	[574,546,860,558]	-3	hSpCas9	negative selection	7762341
40899179	40899202	15	+	27260156	PANC0327	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.9184569209454838	[96]	[65,37,45,34]	-8	hSpCas9	negative selection	7762342
40903296	40903319	15	+	27260156	PANC0327	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.1961368628509507	[437]	[482,576,422,285]	3	hSpCas9	negative selection	7762343
40900906	40900929	15	-	27260156	PANC0327	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.5551336668812534	[291]	[165,153,127,259]	-7	hSpCas9	negative selection	7826589
40898922	40898945	15	+	27260156	PANC0327	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.3976804889457197	[420]	[148,83,254,87]	-9	hSpCas9	negative selection	7826590
40898977	40899000	15	+	27260156	PANC0327	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.014324164692688601	[78]	[34,28,114,106]	0	hSpCas9	negative selection	7826591
40903268	40903291	15	+	27260156	NCIH2009	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.12848198006270095	[821]	[1101,895,1164]	-2	hSpCas9	negative selection	7883592
40899179	40899202	15	+	27260156	NCIH2009	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.20412211802550306	[96]	[115,84,151]	-3	hSpCas9	negative selection	7883593
40903296	40903319	15	+	27260156	NCIH2009	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.6872457190150167	[437]	[1594,761,721]	8	hSpCas9	negative selection	7883594
40900906	40900929	15	-	27260156	NCIH2009	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.0913168805015097	[291]	[279,113,198]	-8	hSpCas9	negative selection	7947840
40898922	40898945	15	+	27260156	NCIH2009	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.8025033733567877	[420]	[337,409,261]	-7	hSpCas9	negative selection	7947841
40898977	40899000	15	+	27260156	NCIH2009	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-1.3991927245515647	[78]	[68,32,28]	-9	hSpCas9	negative selection	7947842
40903268	40903291	15	+	27260156	NCIH1373	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	0.31850658250400576	[821]	[965,1417,1249,230]	3	hSpCas9	negative selection	8004843
40899179	40899202	15	+	27260156	NCIH1373	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.024737549685615257	[96]	[46,149,182,10]	0	hSpCas9	negative selection	8004844
40903296	40903319	15	+	27260156	NCIH1373	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.09076661771945717	[437]	[802,414,322,160]	0	hSpCas9	negative selection	8004845
40900906	40900929	15	-	27260156	NCIH1373	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.7489171990074854	[291]	[55,102,168,12]	-9	hSpCas9	negative selection	8069091
40898922	40898945	15	+	27260156	NCIH1373	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.6380097220908316	[420]	[137,210,40,55]	-9	hSpCas9	negative selection	8069092
40898977	40899000	15	+	27260156	NCIH1373	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.8952008329421095	[78]	[71,13,96,2]	-7	hSpCas9	negative selection	8069093
40903268	40903291	15	+	27260156	PATU8902	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	0.17793406400417466	[821]	[1012,2168,620,1582]	1	hSpCas9	negative selection	8126094
40899179	40899202	15	+	27260156	PATU8902	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.7243012609160335	[96]	[270,324,199,83]	7	hSpCas9	negative selection	8126095
40903296	40903319	15	+	27260156	PATU8902	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.4969353154498539	[437]	[801,1293,526,907]	5	hSpCas9	negative selection	8126096
40900906	40900929	15	-	27260156	PATU8902	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.5651891146241657	[291]	[78,262,73,151]	-8	hSpCas9	negative selection	8190342
40898922	40898945	15	+	27260156	PATU8902	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.9086714131504567	[420]	[259,354,241,421]	-7	hSpCas9	negative selection	8190343
40898977	40899000	15	+	27260156	PATU8902	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.13573087828974906	[78]	[186,77,33,118]	-1	hSpCas9	negative selection	8190344
40903268	40903291	15	+	27260156	PANC1	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.2387509753468241	[821]	[719,618,739,348]	-4	hSpCas9	negative selection	8247345
40899179	40899202	15	+	27260156	PANC1	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.3270699207987251	[96]	[27,135,71,46]	-5	hSpCas9	negative selection	8247346
40903296	40903319	15	+	27260156	PANC1	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.519300126548932	[437]	[570,664,464,480]	8	hSpCas9	negative selection	8247347
40900906	40900929	15	-	27260156	PANC1	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.6869318831541957	[291]	[195,161,142,124]	-7	hSpCas9	negative selection	8311593
40898922	40898945	15	+	27260156	PANC1	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.09327628124216353	[420]	[362,344,418,240]	-1	hSpCas9	negative selection	8311594
40898977	40899000	15	+	27260156	PANC1	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.36177712957575725	[78]	[99,113,75,65]	6	hSpCas9	negative selection	8311595
40903268	40903291	15	+	27260156	PANC0813	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.313242211045693	[821]	[859,668,1082,518]	-5	hSpCas9	negative selection	8368596
40899179	40899202	15	+	27260156	PANC0813	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.18309526481013183	[96]	[168,124,101,124]	3	hSpCas9	negative selection	8368597
40903296	40903319	15	+	27260156	PANC0813	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.2588766515082138	[437]	[440,718,712,574]	4	hSpCas9	negative selection	8368598
40900906	40900929	15	-	27260156	PANC0813	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.8951982206333007	[291]	[179,271,142,143]	-8	hSpCas9	negative selection	8432844
40898922	40898945	15	+	27260156	PANC0813	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6489001766235682	[420]	[215,355,294,380]	-7	hSpCas9	negative selection	8432845
40898977	40899000	15	+	27260156	PANC0813	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-1.9422485722129035	[78]	[29,36,5,23]	-9	hSpCas9	negative selection	8432846
40903268	40903291	15	+	27260156	RDES	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.1784968614252197	[821]	[697,810,846,1019]	-3	hSpCas9	negative selection	8489847
40899179	40899202	15	+	27260156	RDES	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.6902705742942621	[96]	[163,209,112,232]	9	hSpCas9	negative selection	8489848
40903296	40903319	15	+	27260156	RDES	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.24626502007549134	[437]	[492,597,738,563]	4	hSpCas9	negative selection	8489849
40900906	40900929	15	-	27260156	RDES	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.7582388267697366	[291]	[106,146,307,266]	-8	hSpCas9	negative selection	8554095
40898922	40898945	15	+	27260156	RDES	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.7960826641051704	[420]	[201,295,279,355]	-8	hSpCas9	negative selection	8554096
40898977	40899000	15	+	27260156	RDES	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.24567190124318294	[78]	[69,83,100,196]	4	hSpCas9	negative selection	8554097
40903268	40903291	15	+	27260156	PC3	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.14252343369307374	[821]	[448,794,1147,791]	-3	hSpCas9	negative selection	8611098
40899179	40899202	15	+	27260156	PC3	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.17644612274028137	[96]	[62,78,175,58]	-4	hSpCas9	negative selection	8611099
40903296	40903319	15	+	27260156	PC3	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.19970716645239614	[437]	[317,437,872,558]	4	hSpCas9	negative selection	8611100
40900906	40900929	15	-	27260156	PC3	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.10378751165842248	[291]	[204,273,311,306]	-2	hSpCas9	negative selection	8675346
40898922	40898945	15	+	27260156	PC3	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.28264189284701324	[420]	[316,222,461,397]	-6	hSpCas9	negative selection	8675347
40898977	40899000	15	+	27260156	PC3	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.2567720913555247	[78]	[47,146,147,61]	5	hSpCas9	negative selection	8675348
40903268	40903291	15	+	27260156	PATU8988T	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.5539051578336325	[821]	[521,534,537,570]	-7	hSpCas9	negative selection	8732349
40899179	40899202	15	+	27260156	PATU8988T	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.2417020528260485	[96]	[34,82,183,139]	4	hSpCas9	negative selection	8732350
40903296	40903319	15	+	27260156	PATU8988T	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.03234681716770098	[437]	[376,410,342,613]	0	hSpCas9	negative selection	8732351
40900906	40900929	15	-	27260156	PATU8988T	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.1554059089706143	[291]	[123,180,64,143]	-9	hSpCas9	negative selection	8796597
40898922	40898945	15	+	27260156	PATU8988T	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.7060581955104797	[420]	[201,241,292,259]	-8	hSpCas9	negative selection	8796598
40898977	40899000	15	+	27260156	PATU8988T	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.04271487221211734	[78]	[71,22,139,72]	0	hSpCas9	negative selection	8796599
40903268	40903291	15	+	27260156	T47D	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.3380390542699668	[821]	[711,764,827,721]	-6	hSpCas9	negative selection	8853600
40899179	40899202	15	+	27260156	T47D	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	-0.007078401797212752	[96]	[152,118,87,88]	0	hSpCas9	negative selection	8853601
40903296	40903319	15	+	27260156	T47D	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.37615646770423455	[437]	[618,612,704,716]	7	hSpCas9	negative selection	8853602
40900906	40900929	15	-	27260156	T47D	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.5222971236654679	[291]	[200,221,280,243]	-8	hSpCas9	negative selection	8917848
40898922	40898945	15	+	27260156	T47D	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.27112682219344236	[420]	[335,515,367,395]	-5	hSpCas9	negative selection	8917849
40898977	40899000	15	+	27260156	T47D	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.3180023007757167	[78]	[111,75,51,54]	-6	hSpCas9	negative selection	8917850
40903268	40903291	15	+	27260156	SU8686	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.3264449762802388	[821]	[472,638,725,805]	-5	hSpCas9	negative selection	8974851
40899179	40899202	15	+	27260156	SU8686	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.0338604972302079	[96]	[114,67,123,86]	0	hSpCas9	negative selection	8974852
40903296	40903319	15	+	27260156	SU8686	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.13778802577912422	[437]	[472,429,502,514]	2	hSpCas9	negative selection	8974853
40900906	40900929	15	-	27260156	SU8686	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-1.1321152862939061	[291]	[101,112,167,154]	-8	hSpCas9	negative selection	9039099
40898922	40898945	15	+	27260156	SU8686	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.700627558438738	[420]	[273,245,275,223]	-8	hSpCas9	negative selection	9039100
40898977	40899000	15	+	27260156	SU8686	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.36887728135826814	[78]	[94,42,34,67]	-6	hSpCas9	negative selection	9039101
40903268	40903291	15	+	27260156	SKES1	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.2330426082656073	[821]	[679,828,684,612]	-5	hSpCas9	negative selection	9096102
40899179	40899202	15	+	27260156	SKES1	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.4128462062741809	[96]	[121,151,175,71]	8	hSpCas9	negative selection	9096103
40903296	40903319	15	+	27260156	SKES1	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.2736566417562448	[437]	[553,615,469,486]	6	hSpCas9	negative selection	9096104
40900906	40900929	15	-	27260156	SKES1	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.3086476296135847	[291]	[378,223,209,153]	-6	hSpCas9	negative selection	9160350
40898922	40898945	15	+	27260156	SKES1	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.4119773398653382	[420]	[401,378,229,273]	-7	hSpCas9	negative selection	9160351
40898977	40899000	15	+	27260156	SKES1	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.28370104552930897	[78]	[58,188,71,71]	6	hSpCas9	negative selection	9160352
40903268	40903291	15	+	27260156	TOV112D	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.35537111064108634	[821]	[630,802,778,404]	-6	hSpCas9	negative selection	9217353
40899179	40899202	15	+	27260156	TOV112D	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.035871045319590955	[96]	[36,186,37,150]	0	hSpCas9	negative selection	9217354
40903296	40903319	15	+	27260156	TOV112D	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.3803156872201632	[437]	[619,614,600,464]	7	hSpCas9	negative selection	9217355
40900906	40900929	15	-	27260156	TOV112D	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.5423205562962587	[291]	[139,448,217,55]	-8	hSpCas9	negative selection	9281601
40898922	40898945	15	+	27260156	TOV112D	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.19857711302516134	[420]	[271,257,204,689]	-4	hSpCas9	negative selection	9281602
40898977	40899000	15	+	27260156	TOV112D	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	-0.0667841461705847	[78]	[82,186,16,43]	-1	hSpCas9	negative selection	9281603
40903268	40903291	15	+	27260156	TC71	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.40209217379100676	[821]	[644,644,711,663]	-8	hSpCas9	negative selection	9338604
40899179	40899202	15	+	27260156	TC71	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.4253047836053141	[96]	[102,211,119,123]	8	hSpCas9	negative selection	9338605
40903296	40903319	15	+	27260156	TC71	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.24929571868238679	[437]	[601,569,443,622]	6	hSpCas9	negative selection	9338606
40900906	40900929	15	-	27260156	TC71	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.1827172729267431	[291]	[230,352,235,285]	-5	hSpCas9	negative selection	9402852
40898922	40898945	15	+	27260156	TC71	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.3078233043620159	[420]	[367,357,288,450]	-7	hSpCas9	negative selection	9402853
40898977	40899000	15	+	27260156	TC71	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.12584982224670016	[78]	[84,50,121,111]	3	hSpCas9	negative selection	9402854
40903268	40903291	15	+	27260156	TC32	viability	TGATGATCCGCTCTATCGACCGG	VPS18	ENSG00000104142	-0.2164230566815889	[821]	[581,405,914,883]	-4	hSpCas9	negative selection	9459855
40899179	40899202	15	+	27260156	TC32	viability	GTCCTCTACGTGAACCGAAATGG	VPS18	ENSG00000104142	0.1665271608440846	[96]	[128,41,167,94]	3	hSpCas9	negative selection	9459856
40903296	40903319	15	+	27260156	TC32	viability	CATCGACCCCCAGCGCTACGAGG	VPS18	ENSG00000104142	0.3485227019620662	[437]	[407,446,772,523]	6	hSpCas9	negative selection	9459857
40900906	40900929	15	-	27260156	TC32	viability	AGAGCCGCAGCGCATACTTGAGG	VPS18	ENSG00000104142	-0.2726594509729513	[291]	[128,236,201,336]	-5	hSpCas9	negative selection	9524103
40898922	40898945	15	+	27260156	TC32	viability	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.44243907482391337	[420]	[169,345,263,358]	-7	hSpCas9	negative selection	9524104
40898977	40899000	15	+	27260156	TC32	viability	AAGATGTTCCTTGACCATACTGG	VPS18	ENSG00000104142	0.08081754210512049	[78]	[78,72,53,101]	1	hSpCas9	negative selection	9524105
40894826	40894849	15	-	27869803	HPAFII	viability after 27 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.5650180281967931	[98]	[20,46,NaN]	-4	hSpCas9	negative selection	9553491
40896038	40896061	15	+	27869803	HPAFII	viability after 27 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.6540992611067938	[188]	[109,194,NaN]	5	hSpCas9	negative selection	9553492
40898922	40898945	15	+	27869803	HPAFII	viability after 27 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.02656192852622441	[151]	[138,27,NaN]	0	hSpCas9	negative selection	9553493
40898937	40898960	15	-	27869803	HPAFII	viability after 27 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-2.949275256377316	[604]	[26,52,NaN]	-9	hSpCas9	negative selection	9553494
40900852	40900875	15	+	27869803	HPAFII	viability after 27 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.600085900014046	[183]	[20,40,NaN]	-7	hSpCas9	negative selection	9553495
40902687	40902710	15	+	27869803	HPAFII	viability after 27 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-2.0729777561326688	[234]	[54,7,NaN]	-8	hSpCas9	negative selection	9553496
40894826	40894849	15	-	27869803	HPAFII	viability after 15 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.14031928348820744	[98]	[135,71,NaN]	-2	hSpCas9	negative selection	9635940
40896038	40896061	15	+	27869803	HPAFII	viability after 15 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.4378494730337952	[188]	[432,176,NaN]	5	hSpCas9	negative selection	9635941
40898922	40898945	15	+	27869803	HPAFII	viability after 15 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.223229830324555	[151]	[149,215,NaN]	2	hSpCas9	negative selection	9635942
40898937	40898960	15	-	27869803	HPAFII	viability after 15 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.7161944864059073	[604]	[290,139,NaN]	-9	hSpCas9	negative selection	9635943
40900852	40900875	15	+	27869803	HPAFII	viability after 15 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.564684397521475	[183]	[64,67,NaN]	-8	hSpCas9	negative selection	9635944
40902687	40902710	15	+	27869803	HPAFII	viability after 15 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.6058818032455602	[234]	[172,26,NaN]	-8	hSpCas9	negative selection	9635945
40894826	40894849	15	-	27869803	ASPC1	viability after 36 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-0.10725328004306656	[235]	[177,37,34]	-1	hSpCas9	negative selection	9718389
40896038	40896061	15	+	27869803	ASPC1	viability after 36 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.45059845526751185	[496]	[384,251,118]	4	hSpCas9	negative selection	9718390
40898922	40898945	15	+	27869803	ASPC1	viability after 36 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6307542406349647	[293]	[109,108,0]	-6	hSpCas9	negative selection	9718391
40898937	40898960	15	-	27869803	ASPC1	viability after 36 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-1.4989731509254918	[1720]	[88,369,171]	-8	hSpCas9	negative selection	9718392
40900852	40900875	15	+	27869803	ASPC1	viability after 36 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-2.0725584372993717	[412]	[17,74,12]	-9	hSpCas9	negative selection	9718393
40902687	40902710	15	+	27869803	ASPC1	viability after 36 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-1.182121906197818	[473]	[111,93,27]	-8	hSpCas9	negative selection	9718394
40894826	40894849	15	-	27869803	PATU8988S	viability after 35 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.1970136237874205	[142]	[74,56,NaN]	2	hSpCas9	negative selection	9800838
40896038	40896061	15	+	27869803	PATU8988S	viability after 35 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.06090319481135564	[412]	[141,176,NaN]	0	hSpCas9	negative selection	9800839
40898922	40898945	15	+	27869803	PATU8988S	viability after 35 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-1.0291472475832086	[331]	[73,56,NaN]	-7	hSpCas9	negative selection	9800840
40898937	40898960	15	-	27869803	PATU8988S	viability after 35 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	0.3627796339911349	[1252]	[834,461,NaN]	4	hSpCas9	negative selection	9800841
40900852	40900875	15	+	27869803	PATU8988S	viability after 35 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.8642852056633932	[428]	[27,66,NaN]	-9	hSpCas9	negative selection	9800842
40902687	40902710	15	+	27869803	PATU8988S	viability after 35 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	0.19697535273048258	[583]	[319,218,NaN]	2	hSpCas9	negative selection	9800843
40894826	40894849	15	-	27869803	PATU8988S	viability after 31 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	0.6666043997448323	[142]	[42,150,NaN]	7	hSpCas9	negative selection	9883287
40896038	40896061	15	+	27869803	PATU8988S	viability after 31 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	-0.4356923617494371	[412]	[97,151,NaN]	-5	hSpCas9	negative selection	9883288
40898922	40898945	15	+	27869803	PATU8988S	viability after 31 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6365281237894063	[331]	[67,106,NaN]	-6	hSpCas9	negative selection	9883289
40898937	40898960	15	-	27869803	PATU8988S	viability after 31 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	0.3054620156363199	[1252]	[638,589,NaN]	4	hSpCas9	negative selection	9883290
40900852	40900875	15	+	27869803	PATU8988S	viability after 31 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-0.3727091233549645	[428]	[110,158,NaN]	-4	hSpCas9	negative selection	9883291
40902687	40902710	15	+	27869803	PATU8988S	viability after 31 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	0.017107714534176727	[583]	[254,210,NaN]	0	hSpCas9	negative selection	9883292
40894826	40894849	15	-	27869803	HPAFII	viability after 35 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-1.3388031229949002	[98]	[0,40,NaN]	-6	hSpCas9	negative selection	9965736
40896038	40896061	15	+	27869803	HPAFII	viability after 35 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.9299261649490959	[188]	[51,328,NaN]	6	hSpCas9	negative selection	9965737
40898922	40898945	15	+	27869803	HPAFII	viability after 35 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	-0.6199313831130306	[151]	[74,21,NaN]	-4	hSpCas9	negative selection	9965738
40898937	40898960	15	-	27869803	HPAFII	viability after 35 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-2.5104834072524502	[604]	[25,84,NaN]	-8	hSpCas9	negative selection	9965739
40900852	40900875	15	+	27869803	HPAFII	viability after 35 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-1.9418545264876284	[183]	[43,1,NaN]	-7	hSpCas9	negative selection	9965740
40902687	40902710	15	+	27869803	HPAFII	viability after 35 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-5.027235130616861	[234]	[5,0,NaN]	-9	hSpCas9	negative selection	9965741
40894826	40894849	15	-	27869803	HPAFII	viability after 31 days	ATGCCCACGCTAGGGCAGCCGGG	VPS18	ENSG00000104142	-1.8558186699215347	[98]	[11,18,NaN]	-8	hSpCas9	negative selection	10048185
40896038	40896061	15	+	27869803	HPAFII	viability after 31 days	CAATCAGCTGTGCATGAGCCTGG	VPS18	ENSG00000104142	0.9698334422245296	[188]	[123,298,NaN]	7	hSpCas9	negative selection	10048186
40898922	40898945	15	+	27869803	HPAFII	viability after 31 days	GGCAAATGAGCCCAACCACGTGG	VPS18	ENSG00000104142	0.22227542687342838	[151]	[177,13,NaN]	1	hSpCas9	negative selection	10048187
40898937	40898960	15	-	27869803	HPAFII	viability after 31 days	CCTTACGTCCCAGCTCCACGTGG	VPS18	ENSG00000104142	-2.2579633228815554	[604]	[25,119,NaN]	-8	hSpCas9	negative selection	10048188
40900852	40900875	15	+	27869803	HPAFII	viability after 31 days	ACTACTGGCCTATCTGGAGCAGG	VPS18	ENSG00000104142	-2.791567776756837	[183]	[12,16,NaN]	-8	hSpCas9	negative selection	10048189
40902687	40902710	15	+	27869803	HPAFII	viability after 31 days	GCTGAAGATCGCACGGCACGTGG	VPS18	ENSG00000104142	-3.4025909202052684	[234]	[22,0,NaN]	-9	hSpCas9	negative selection	10048190
40899332	40899355	15	+	28162770	P31FUJ	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.7427513507186895	[177]	[124]	-5	hSpCas9	negative selection	10263696
40900592	40900615	15	-	28162770	P31FUJ	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.4845854752734635	[280]	[117]	-7	hSpCas9	negative selection	10263697
40899483	40899506	15	-	28162770	P31FUJ	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-1.817764705135535	[83]	[27]	-8	hSpCas9	negative selection	10263698
40899826	40899849	15	+	28162770	P31FUJ	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.8998189210180205	[207]	[130]	-6	hSpCas9	negative selection	10263699
40899397	40899420	15	+	28162770	P31FUJ	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-1.0580278033106705	[263]	[148]	-6	hSpCas9	negative selection	10263700
40899540	40899563	15	-	28162770	P31FUJ	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.1983138280290879	[247]	[253]	-2	hSpCas9	negative selection	10263701
40899745	40899768	15	+	28162770	P31FUJ	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.62040647357011	[381]	[145]	-7	hSpCas9	negative selection	10263702
40899853	40899876	15	+	28162770	P31FUJ	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.780289999716872	[151]	[103]	-6	hSpCas9	negative selection	10263703
40900183	40900206	15	+	28162770	P31FUJ	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.33307943287285036	[416]	[388]	-3	hSpCas9	negative selection	10263704
40900540	40900563	15	+	28162770	P31FUJ	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.30875105764767724	[272]	[258]	-3	hSpCas9	negative selection	10263705
40899332	40899355	15	+	28162770	TF1	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10433062
40900592	40900615	15	-	28162770	TF1	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10433063
40899483	40899506	15	-	28162770	TF1	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10433064
40899826	40899849	15	+	28162770	TF1	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10433065
40899397	40899420	15	+	28162770	TF1	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10433066
40899540	40899563	15	-	28162770	TF1	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10433067
40899745	40899768	15	+	28162770	TF1	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10433068
40899853	40899876	15	+	28162770	TF1	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10433069
40900183	40900206	15	+	28162770	TF1	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10433070
40900540	40900563	15	+	28162770	TF1	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10433071
40899332	40899355	15	+	28162770	SKM1	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.5809935985182105	[54]	[64]	-4	hSpCas9	negative selection	10602428
40900592	40900615	15	-	28162770	SKM1	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.496601411227838	[82]	[51]	-7	hSpCas9	negative selection	10602429
40899483	40899506	15	-	28162770	SKM1	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.1912355076877246	[30]	[11]	-8	hSpCas9	negative selection	10602430
40899826	40899849	15	+	28162770	SKM1	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-2.6887351671585416	[61]	[16]	-9	hSpCas9	negative selection	10602431
40899397	40899420	15	+	28162770	SKM1	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.6226928897985987	[80]	[92]	-5	hSpCas9	negative selection	10602432
40899540	40899563	15	-	28162770	SKM1	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.19237014796712093	[52]	[81]	-2	hSpCas9	negative selection	10602433
40899745	40899768	15	+	28162770	SKM1	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-2.8594764034406683	[77]	[18]	-9	hSpCas9	negative selection	10602434
40899853	40899876	15	+	28162770	SKM1	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	0.5158679407343784	[35]	[90]	5	hSpCas9	negative selection	10602435
40900183	40900206	15	+	28162770	SKM1	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.934476427280418	[79]	[73]	-6	hSpCas9	negative selection	10602436
40900540	40900563	15	+	28162770	SKM1	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.8801046525855738	[75]	[72]	-6	hSpCas9	negative selection	10602437
40899332	40899355	15	+	28162770	SKM1	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.5809935985182105	[54]	[64]	-4	hSpCas9	negative selection	10771794
40900592	40900615	15	-	28162770	SKM1	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.496601411227838	[82]	[51]	-7	hSpCas9	negative selection	10771795
40899483	40899506	15	-	28162770	SKM1	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.1912355076877246	[30]	[11]	-8	hSpCas9	negative selection	10771796
40899826	40899849	15	+	28162770	SKM1	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-2.6887351671585416	[61]	[16]	-9	hSpCas9	negative selection	10771797
40899397	40899420	15	+	28162770	SKM1	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.6226928897985987	[80]	[92]	-5	hSpCas9	negative selection	10771798
40899540	40899563	15	-	28162770	SKM1	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.19237014796712093	[52]	[81]	-2	hSpCas9	negative selection	10771799
40899745	40899768	15	+	28162770	SKM1	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-2.8594764034406683	[77]	[18]	-9	hSpCas9	negative selection	10771800
40899853	40899876	15	+	28162770	SKM1	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	0.5158679407343784	[35]	[90]	5	hSpCas9	negative selection	10771801
40900183	40900206	15	+	28162770	SKM1	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.934476427280418	[79]	[73]	-6	hSpCas9	negative selection	10771802
40900540	40900563	15	+	28162770	SKM1	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.8801046525855738	[75]	[72]	-6	hSpCas9	negative selection	10771803
40899332	40899355	15	+	28162770	PL21	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.6948908259091371	[211]	[56]	-5	hSpCas9	negative selection	10941160
40900592	40900615	15	-	28162770	PL21	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-0.47681867031260916	[258]	[80]	-3	hSpCas9	negative selection	10941161
40899483	40899506	15	-	28162770	PL21	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.6743295034268213	[131]	[8]	-9	hSpCas9	negative selection	10941162
40899826	40899849	15	+	28162770	PL21	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.9962575983141833	[274]	[59]	-6	hSpCas9	negative selection	10941163
40899397	40899420	15	+	28162770	PL21	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	0.868296050736875	[291]	[231]	7	hSpCas9	negative selection	10941164
40899540	40899563	15	-	28162770	PL21	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	0.6449244571622159	[215]	[146]	5	hSpCas9	negative selection	10941165
40899745	40899768	15	+	28162770	PL21	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-0.24527153383304254	[255]	[93]	-2	hSpCas9	negative selection	10941166
40899853	40899876	15	+	28162770	PL21	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-1.500300103651772	[77]	[11]	-7	hSpCas9	negative selection	10941167
40900183	40900206	15	+	28162770	PL21	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	0.11510351063352087	[296]	[139]	1	hSpCas9	negative selection	10941168
40900540	40900563	15	+	28162770	PL21	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.38482288623183614	[182]	[60]	-3	hSpCas9	negative selection	10941169
40899332	40899355	15	+	28162770	P31FUJ	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.7427513507186895	[177]	[124]	-5	hSpCas9	negative selection	11110526
40900592	40900615	15	-	28162770	P31FUJ	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.4845854752734635	[280]	[117]	-7	hSpCas9	negative selection	11110527
40899483	40899506	15	-	28162770	P31FUJ	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-1.817764705135535	[83]	[27]	-8	hSpCas9	negative selection	11110528
40899826	40899849	15	+	28162770	P31FUJ	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.8998189210180205	[207]	[130]	-6	hSpCas9	negative selection	11110529
40899397	40899420	15	+	28162770	P31FUJ	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-1.0580278033106705	[263]	[148]	-6	hSpCas9	negative selection	11110530
40899540	40899563	15	-	28162770	P31FUJ	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.1983138280290879	[247]	[253]	-2	hSpCas9	negative selection	11110531
40899745	40899768	15	+	28162770	P31FUJ	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.62040647357011	[381]	[145]	-7	hSpCas9	negative selection	11110532
40899853	40899876	15	+	28162770	P31FUJ	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.780289999716872	[151]	[103]	-6	hSpCas9	negative selection	11110533
40900183	40900206	15	+	28162770	P31FUJ	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.33307943287285036	[416]	[388]	-3	hSpCas9	negative selection	11110534
40900540	40900563	15	+	28162770	P31FUJ	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.30875105764767724	[272]	[258]	-3	hSpCas9	negative selection	11110535
40899332	40899355	15	+	28162770	OCIAML5	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.9843143691624365	[136]	[124]	-6	hSpCas9	negative selection	11279892
40900592	40900615	15	-	28162770	OCIAML5	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.1098643283316436	[164]	[137]	-6	hSpCas9	negative selection	11279893
40899483	40899506	15	-	28162770	OCIAML5	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-0.5379579804359338	[36]	[45]	-4	hSpCas9	negative selection	11279894
40899826	40899849	15	+	28162770	OCIAML5	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-1.4705037761362414	[108]	[70]	-7	hSpCas9	negative selection	11279895
40899397	40899420	15	+	28162770	OCIAML5	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	0.5596581943740113	[108]	[289]	5	hSpCas9	negative selection	11279896
40899540	40899563	15	-	28162770	OCIAML5	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.461607094305819	[147]	[193]	-3	hSpCas9	negative selection	11279897
40899745	40899768	15	+	28162770	OCIAML5	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.232209279696655	[176]	[135]	-6	hSpCas9	negative selection	11279898
40899853	40899876	15	+	28162770	OCIAML5	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.23431413502517162	[57]	[88]	-2	hSpCas9	negative selection	11279899
40900183	40900206	15	+	28162770	OCIAML5	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.8049325952729021	[270]	[279]	-5	hSpCas9	negative selection	11279900
40900540	40900563	15	+	28162770	OCIAML5	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-1.1642795109181476	[184]	[148]	-6	hSpCas9	negative selection	11279901
40899332	40899355	15	+	28162770	EOL1	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-2.48672780891211	[382]	[35]	-8	hSpCas9	negative selection	11449258
40900592	40900615	15	-	28162770	EOL1	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-0.1379936944981784	[329]	[157]	-1	hSpCas9	negative selection	11449259
40899483	40899506	15	-	28162770	EOL1	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.131305463162983	[157]	[18]	-8	hSpCas9	negative selection	11449260
40899826	40899849	15	+	28162770	EOL1	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-1.4554832778803959	[379]	[72]	-7	hSpCas9	negative selection	11449261
40899397	40899420	15	+	28162770	EOL1	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.6272478652154223	[515]	[175]	-4	hSpCas9	negative selection	11449262
40899540	40899563	15	-	28162770	EOL1	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.4396654686306267	[501]	[194]	-3	hSpCas9	negative selection	11449263
40899745	40899768	15	+	28162770	EOL1	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-0.8583541067625307	[350]	[101]	-5	hSpCas9	negative selection	11449264
40899853	40899876	15	+	28162770	EOL1	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-1.5483881114165108	[160]	[28]	-7	hSpCas9	negative selection	11449265
40900183	40900206	15	+	28162770	EOL1	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	0.2493874618778002	[395]	[247]	2	hSpCas9	negative selection	11449266
40900540	40900563	15	+	28162770	EOL1	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.17040063248472792	[313]	[146]	-1	hSpCas9	negative selection	11449267
40899332	40899355	15	+	28162770	MOLM13	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-2.7276614275732283	[283]	[30]	-8	hSpCas9	negative selection	11618624
40900592	40900615	15	-	28162770	MOLM13	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-0.6943820473542982	[328]	[146]	-4	hSpCas9	negative selection	11618625
40899483	40899506	15	-	28162770	MOLM13	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.4104320618671684	[124]	[16]	-8	hSpCas9	negative selection	11618626
40899826	40899849	15	+	28162770	MOLM13	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-3.4098548684044236	[293]	[19]	-8	hSpCas9	negative selection	11618627
40899397	40899420	15	+	28162770	MOLM13	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.6447684192248831	[425]	[196]	-4	hSpCas9	negative selection	11618628
40899540	40899563	15	-	28162770	MOLM13	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.9324516065275631	[292]	[110]	-5	hSpCas9	negative selection	11618629
40899745	40899768	15	+	28162770	MOLM13	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-2.6232585065136163	[391]	[45]	-8	hSpCas9	negative selection	11618630
40899853	40899876	15	+	28162770	MOLM13	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-2.941501554593123	[254]	[23]	-8	hSpCas9	negative selection	11618631
40900183	40900206	15	+	28162770	MOLM13	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.9503648304178078	[448]	[167]	-5	hSpCas9	negative selection	11618632
40900540	40900563	15	+	28162770	MOLM13	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.5096732293356658	[318]	[161]	-3	hSpCas9	negative selection	11618633
40899332	40899355	15	+	28162770	HEL	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-2.1873361665573303	[255]	[35]	-8	hSpCas9	negative selection	11787990
40900592	40900615	15	-	28162770	HEL	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.7607767973832673	[290]	[54]	-7	hSpCas9	negative selection	11787991
40899483	40899506	15	-	28162770	HEL	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-3.087654108242363	[145]	[10]	-9	hSpCas9	negative selection	11787992
40899826	40899849	15	+	28162770	HEL	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-0.9895293834991559	[278]	[89]	-6	hSpCas9	negative selection	11787993
40899397	40899420	15	+	28162770	HEL	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	0.20877160418666207	[357]	[264]	1	hSpCas9	negative selection	11787994
40899540	40899563	15	-	28162770	HEL	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.12714138463858432	[265]	[155]	-1	hSpCas9	negative selection	11787995
40899745	40899768	15	+	28162770	HEL	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.7978337593856244	[265]	[48]	-7	hSpCas9	negative selection	11787996
40899853	40899876	15	+	28162770	HEL	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.7531898443307823	[149]	[56]	-5	hSpCas9	negative selection	11787997
40900183	40900206	15	+	28162770	HEL	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-3.2174035044166827	[333]	[22]	-9	hSpCas9	negative selection	11787998
40900540	40900563	15	+	28162770	HEL	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.5041025563289141	[185]	[83]	-3	hSpCas9	negative selection	11787999
40899332	40899355	15	+	28162770	MV411	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-1.8003155806655928	[214]	[51]	-8	hSpCas9	negative selection	11957356
40900592	40900615	15	-	28162770	MV411	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-3.4209409581260184	[266]	[20]	-9	hSpCas9	negative selection	11957357
40899483	40899506	15	-	28162770	MV411	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-1.3872779851354806	[117]	[37]	-7	hSpCas9	negative selection	11957358
40899826	40899849	15	+	28162770	MV411	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	0.2830614605134968	[159]	[163]	2	hSpCas9	negative selection	11957359
40899397	40899420	15	+	28162770	MV411	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	0.006429451278980425	[324]	[274]	0	hSpCas9	negative selection	11957360
40899540	40899563	15	-	28162770	MV411	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	0.34770167425620446	[263]	[282]	3	hSpCas9	negative selection	11957361
40899745	40899768	15	+	28162770	MV411	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-1.0679178901811008	[218]	[87]	-6	hSpCas9	negative selection	11957362
40899853	40899876	15	+	28162770	MV411	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	0.3761708649049783	[74]	[81]	3	hSpCas9	negative selection	11957363
40900183	40900206	15	+	28162770	MV411	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.12201891418717292	[269]	[208]	-1	hSpCas9	negative selection	11957364
40900540	40900563	15	+	28162770	MV411	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.6756936858329543	[200]	[105]	-5	hSpCas9	negative selection	11957365
40899332	40899355	15	+	28162770	MONOMAC1	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-0.5536019436189334	[136]	[106]	-5	hSpCas9	negative selection	12126722
40900592	40900615	15	-	28162770	MONOMAC1	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-1.625880145863428	[174]	[64]	-8	hSpCas9	negative selection	12126723
40899483	40899506	15	-	28162770	MONOMAC1	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.386861405939571	[72]	[15]	-9	hSpCas9	negative selection	12126724
40899826	40899849	15	+	28162770	MONOMAC1	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-2.741357363283364	[139]	[23]	-9	hSpCas9	negative selection	12126725
40899397	40899420	15	+	28162770	MONOMAC1	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-0.9572098323870852	[187]	[110]	-6	hSpCas9	negative selection	12126726
40899540	40899563	15	-	28162770	MONOMAC1	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.6307935436849864	[180]	[133]	-5	hSpCas9	negative selection	12126727
40899745	40899768	15	+	28162770	MONOMAC1	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-3.0322259773138835	[156]	[21]	-9	hSpCas9	negative selection	12126728
40899853	40899876	15	+	28162770	MONOMAC1	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.5531806572848291	[63]	[49]	-5	hSpCas9	negative selection	12126729
40900183	40900206	15	+	28162770	MONOMAC1	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-1.2595783131282665	[164]	[78]	-7	hSpCas9	negative selection	12126730
40900540	40900563	15	+	28162770	MONOMAC1	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-0.7226652083983075	[130]	[90]	-5	hSpCas9	negative selection	12126731
40899332	40899355	15	+	28162770	OCIAML2	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-1.516433514855286	[31]	[61]	-7	hSpCas9	negative selection	12296088
40900592	40900615	15	-	28162770	OCIAML2	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-3.0962343104606638	[53]	[34]	-9	hSpCas9	negative selection	12296089
40899483	40899506	15	-	28162770	OCIAML2	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.8856673245210054	[15]	[11]	-9	hSpCas9	negative selection	12296090
40899826	40899849	15	+	28162770	OCIAML2	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-1.6980403213452337	[23]	[40]	-7	hSpCas9	negative selection	12296091
40899397	40899420	15	+	28162770	OCIAML2	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-1.371094151691247	[55]	[119]	-7	hSpCas9	negative selection	12296092
40899540	40899563	15	-	28162770	OCIAML2	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	-0.790510091480665	[43]	[140]	-5	hSpCas9	negative selection	12296093
40899745	40899768	15	+	28162770	OCIAML2	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-2.1169928706274606	[35]	[45]	-8	hSpCas9	negative selection	12296094
40899853	40899876	15	+	28162770	OCIAML2	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-1.005961558238717	[24]	[68]	-6	hSpCas9	negative selection	12296095
40900183	40900206	15	+	28162770	OCIAML2	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-1.749783896439232	[53]	[88]	-8	hSpCas9	negative selection	12296096
40900540	40900563	15	+	28162770	OCIAML2	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	-1.2428239077193488	[37]	[88]	-7	hSpCas9	negative selection	12296097
40899332	40899355	15	+	28162770	OCIAML3	viability	GCAGAGCTCTCAGCCAGCGAAGG	VPS18	ENSG00000104142	-1.5940076403241632	[71]	[71]	-8	hSpCas9	negative selection	12465454
40900592	40900615	15	-	28162770	OCIAML3	viability	GAGAACTTGTAGAAGAGCTGGGG	VPS18	ENSG00000104142	-0.9482911085239107	[61]	[96]	-6	hSpCas9	negative selection	12465455
40899483	40899506	15	-	28162770	OCIAML3	viability	GAAGAGGCGCTGCCGAGTGGTGG	VPS18	ENSG00000104142	-2.0858607366538378	[44]	[31]	-8	hSpCas9	negative selection	12465456
40899826	40899849	15	+	28162770	OCIAML3	viability	GCTGCTACTGGCAGACCGGGTGG	VPS18	ENSG00000104142	-2.8034610059531127	[73]	[31]	-9	hSpCas9	negative selection	12465457
40899397	40899420	15	+	28162770	OCIAML3	viability	GTACGTGCTAAATGAAGAAGGGG	VPS18	ENSG00000104142	-1.1215198688614199	[79]	[110]	-7	hSpCas9	negative selection	12465458
40899540	40899563	15	-	28162770	OCIAML3	viability	AAAGAGCCCTGAGAAACCCTGGG	VPS18	ENSG00000104142	0.33510887351932717	[72]	[277]	3	hSpCas9	negative selection	12465459
40899745	40899768	15	+	28162770	OCIAML3	viability	GCGAGTCTGGGAGTACCCAGAGG	VPS18	ENSG00000104142	-3.459078060238055	[50]	[13]	-9	hSpCas9	negative selection	12465460
40899853	40899876	15	+	28162770	OCIAML3	viability	AGTGTGCACACTGACCGGGCAGG	VPS18	ENSG00000104142	-0.4181578049247455	[26]	[60]	-3	hSpCas9	negative selection	12465461
40900183	40900206	15	+	28162770	OCIAML3	viability	GATTGCCCTCAAGTTCCTGGAGG	VPS18	ENSG00000104142	-0.09717604988167217	[89]	[253]	0	hSpCas9	negative selection	12465462
40900540	40900563	15	+	28162770	OCIAML3	viability	TCAGCACGAGGCCTACGAGGAGG	VPS18	ENSG00000104142	0.3902250438175201	[45]	[181]	3	hSpCas9	negative selection	12465463