Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 26276
• Symbol: VPS33B
• Description: VPS33B late endosome and lysosome associated

DataSource: http://genomecrispr.dkfz.de/#!/results/VPS33B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
91007007	91007030	15	-	26472758	Jiyoye	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-0.3400585481141596	[46]	[27]	-2	hSpCas9	negative selection	180062
91002092	91002115	15	+	26472758	Jiyoye	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	-0.6139892284921691	[411]	[202]	-4	hSpCas9	negative selection	180063
91006377	91006400	15	-	26472758	Jiyoye	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.3563710108343823	[288]	[278]	2	hSpCas9	negative selection	180064
91017793	91017816	15	+	26472758	Jiyoye	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.8501188773546017	[63]	[86]	6	hSpCas9	negative selection	180065
91006991	91007014	15	-	26472758	Jiyoye	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.8553211925966557	[139]	[190]	6	hSpCas9	negative selection	180066
91004869	91004892	15	+	26472758	Jiyoye	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.7269958134312445	[136]	[170]	5	hSpCas9	negative selection	180067
91000527	91000550	15	-	26472758	Jiyoye	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	1.7962176722517726	[20]	[54]	8	hSpCas9	negative selection	180068
91009800	91009823	15	-	26472758	Jiyoye	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	0.3305540999029608	[289]	[274]	2	hSpCas9	negative selection	180069
91005072	91005095	15	-	26472758	Jiyoye	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.6681127457983639	[294]	[139]	-5	hSpCas9	negative selection	180070
91004892	91004915	15	+	26472758	Jiyoye	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.1473082547507626	[90]	[75]	1	hSpCas9	negative selection	180071
91007007	91007030	15	-	26472758	KBM7	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	0.6762743124942281	[113,101]	[88,73]	7	hSpCas9	negative selection	371180
91002092	91002115	15	+	26472758	KBM7	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	1.0840010634886275	[913,572]	[645,799]	9	hSpCas9	negative selection	371181
91006377	91006400	15	-	26472758	KBM7	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.16546610049529925	[890,601]	[283,329]	-2	hSpCas9	negative selection	371182
91017793	91017816	15	+	26472758	KBM7	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.8509707246818492	[425,210]	[363,170]	8	hSpCas9	negative selection	371183
91006991	91007014	15	-	26472758	KBM7	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	-0.004338610869504933	[714,495]	[355,211]	0	hSpCas9	negative selection	371184
91004869	91004892	15	+	26472758	KBM7	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.635377173285558	[676,632]	[675,302]	7	hSpCas9	negative selection	371185
91000527	91000550	15	-	26472758	KBM7	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.35965002256585077	[559,389]	[176,166]	-3	hSpCas9	negative selection	371186
91009800	91009823	15	-	26472758	KBM7	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.4113767542308766	[1469,1227]	[467,480]	-4	hSpCas9	negative selection	371187
91005072	91005095	15	-	26472758	KBM7	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.20815139743876732	[1008,832]	[315,423]	-2	hSpCas9	negative selection	371188
91004892	91004915	15	+	26472758	KBM7	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.6197829636966634	[385,405]	[226,342]	6	hSpCas9	negative selection	371189
91007007	91007030	15	-	26472758	Raji	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-0.8926164646264005	[103]	[12]	-6	hSpCas9	negative selection	562298
91002092	91002115	15	+	26472758	Raji	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.19449419914363775	[481]	[127]	1	hSpCas9	negative selection	562299
91006377	91006400	15	-	26472758	Raji	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.23838954752360952	[262]	[71]	2	hSpCas9	negative selection	562300
91017793	91017816	15	+	26472758	Raji	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.22868983159573297	[113]	[30]	2	hSpCas9	negative selection	562301
91006991	91007014	15	-	26472758	Raji	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.1504522572654855	[263]	[67]	1	hSpCas9	negative selection	562302
91004869	91004892	15	+	26472758	Raji	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	-0.16762351212627033	[241]	[49]	-1	hSpCas9	negative selection	562303
91000527	91000550	15	-	26472758	Raji	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.3455432725683641	[155]	[45]	3	hSpCas9	negative selection	562304
91009800	91009823	15	-	26472758	Raji	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.8267285289699433	[855]	[111]	-6	hSpCas9	negative selection	562305
91005072	91005095	15	-	26472758	Raji	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.9969531244411363	[515]	[59]	-6	hSpCas9	negative selection	562306
91004892	91004915	15	+	26472758	Raji	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.7088341588833247	[144]	[54]	6	hSpCas9	negative selection	562307
91007007	91007030	15	-	26472758	K562	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-2.3185174667247104	[129]	[21]	-8	hSpCas9	negative selection	753416
91002092	91002115	15	+	26472758	K562	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.8902364337744576	[440]	[689]	7	hSpCas9	negative selection	753417
91006377	91006400	15	-	26472758	K562	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.3451165028445334	[473]	[314]	-2	hSpCas9	negative selection	753418
91017793	91017816	15	+	26472758	K562	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.576262291418892	[289]	[364]	5	hSpCas9	negative selection	753419
91006991	91007014	15	-	26472758	K562	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	-0.2119595669932963	[471]	[343]	-1	hSpCas9	negative selection	753420
91004869	91004892	15	+	26472758	K562	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.27002937134548444	[669]	[681]	2	hSpCas9	negative selection	753421
91000527	91000550	15	-	26472758	K562	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.5804679307984619	[304]	[384]	5	hSpCas9	negative selection	753422
91009800	91009823	15	-	26472758	K562	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-1.055230125579718	[1252]	[508]	-5	hSpCas9	negative selection	753423
91005072	91005095	15	-	26472758	K562	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.5130109690594749	[851]	[503]	-3	hSpCas9	negative selection	753424
91004892	91004915	15	+	26472758	K562	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.4720194400056559	[315]	[369]	4	hSpCas9	negative selection	753425
91005685	91005708	15	+	26627737	DLD1	viability	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.5794954458624577	[88]	[50,5,0]	-5	hSpCas9	negative selection	792402
91006377	91006400	15	-	26627737	DLD1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.232260320081484	[331]	[223,55,87]	2	hSpCas9	negative selection	792403
91006647	91006670	15	+	26627737	DLD1	viability	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.2157093513677062	[601]	[159,213,272]	2	hSpCas9	negative selection	792404
91007013	91007036	15	-	26627737	DLD1	viability	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.5240750885965927	[231]	[56,31,59]	-5	hSpCas9	negative selection	792405
91009828	91009851	15	-	26627737	DLD1	viability	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.4870673533569459	[456]	[200,218,183]	5	hSpCas9	negative selection	792406
91022156	91022179	15	+	26627737	DLD1	viability	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.38089994498364543	[256]	[39,114,151]	4	hSpCas9	negative selection	792407
91005685	91005708	15	+	26627737	GBM cells	viability after 5 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	0.19264507794239583	[61]	[23,51]	3	hSpCas9	negative selection	874717
91006377	91006400	15	-	26627737	GBM cells	viability after 5 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.23435265597777866	[169]	[73,80]	-4	hSpCas9	negative selection	874718
91006647	91006670	15	+	26627737	GBM cells	viability after 5 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.23810560422260443	[297]	[143,126]	-4	hSpCas9	negative selection	874719
91007013	91007036	15	-	26627737	GBM cells	viability after 5 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.4868698194180442	[178]	[62,73]	-6	hSpCas9	negative selection	874720
91009828	91009851	15	-	26627737	GBM cells	viability after 5 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.20703617024801743	[272]	[175,161]	3	hSpCas9	negative selection	874721
91022156	91022179	15	+	26627737	GBM cells	viability after 5 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.4838763756068417	[205]	[167,140]	7	hSpCas9	negative selection	874722
91005685	91005708	15	+	26627737	GBM cells	viability after 13 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.3716534686673354	[61]	[25,25]	-4	hSpCas9	negative selection	957032
91006377	91006400	15	-	26627737	GBM cells	viability after 13 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.9425463298455604	[169]	[31,60]	-8	hSpCas9	negative selection	957033
91006647	91006670	15	+	26627737	GBM cells	viability after 13 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.2056819971653523	[297]	[218,159]	2	hSpCas9	negative selection	957034
91007013	91007036	15	-	26627737	GBM cells	viability after 13 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-1.0855491499499565	[178]	[58,34]	-8	hSpCas9	negative selection	957035
91009828	91009851	15	-	26627737	GBM cells	viability after 13 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.5611267193712373	[272]	[276,170]	7	hSpCas9	negative selection	957036
91022156	91022179	15	+	26627737	GBM cells	viability after 13 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.674610078291199	[205]	[157,194]	7	hSpCas9	negative selection	957037
91005685	91005708	15	+	26627737	GBM cells	viability after 21 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.9978600316854251	[61]	[19,13]	-7	hSpCas9	negative selection	1039347
91006377	91006400	15	-	26627737	GBM cells	viability after 21 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.023554149960907544	[169]	[84,101]	0	hSpCas9	negative selection	1039348
91006647	91006670	15	+	26627737	GBM cells	viability after 21 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.11279066464894777	[297]	[167,132]	-1	hSpCas9	negative selection	1039349
91007013	91007036	15	-	26627737	GBM cells	viability after 21 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.894843436289019	[178]	[56,47]	-6	hSpCas9	negative selection	1039350
91009828	91009851	15	-	26627737	GBM cells	viability after 21 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.5393920943279836	[272]	[225,205]	5	hSpCas9	negative selection	1039351
91022156	91022179	15	+	26627737	GBM cells	viability after 21 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.18971970992581658	[205]	[135,119]	2	hSpCas9	negative selection	1039352
91005685	91005708	15	+	26627737	RPE1	viability after 9 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	3.07687359807501	[8]	[35,7]	9	hSpCas9	negative selection	1121662
91006377	91006400	15	-	26627737	RPE1	viability after 9 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.23054206738661231	[301]	[44,195]	1	hSpCas9	negative selection	1121663
91006647	91006670	15	+	26627737	RPE1	viability after 9 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	2.480434261290948	[107]	[251,106]	9	hSpCas9	negative selection	1121664
91007013	91007036	15	-	26627737	RPE1	viability after 9 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-2.4959956602891813	[602]	[15,55]	-9	hSpCas9	negative selection	1121665
91009828	91009851	15	-	26627737	RPE1	viability after 9 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.1824591816553583	[885]	[326,298]	1	hSpCas9	negative selection	1121666
91022156	91022179	15	+	26627737	RPE1	viability after 9 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.5775628977961773	[431]	[148,269]	4	hSpCas9	negative selection	1121667
91005685	91005708	15	+	26627737	RPE1	viability after 12 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	2.671044856038364	[8]	[28,0]	9	hSpCas9	negative selection	1203977
91006377	91006400	15	-	26627737	RPE1	viability after 12 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.3533823959316149	[301]	[91,115]	2	hSpCas9	negative selection	1203978
91006647	91006670	15	+	26627737	RPE1	viability after 12 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	1.838886542980188	[107]	[130,74]	8	hSpCas9	negative selection	1203979
91007013	91007036	15	-	26627737	RPE1	viability after 12 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-3.678022908616895	[602]	[0,24]	-9	hSpCas9	negative selection	1203980
91009828	91009851	15	-	26627737	RPE1	viability after 12 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.12032374900503529	[885]	[266,249]	0	hSpCas9	negative selection	1203981
91022156	91022179	15	+	26627737	RPE1	viability after 12 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.22048009930306645	[431]	[210,54]	1	hSpCas9	negative selection	1203982
91005685	91005708	15	+	26627737	RPE1	viability after 15 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	3.847093075226158	[8]	[56,16]	9	hSpCas9	negative selection	1286292
91006377	91006400	15	-	26627737	RPE1	viability after 15 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.2855716762800151	[301]	[124,83]	1	hSpCas9	negative selection	1286293
91006647	91006670	15	+	26627737	RPE1	viability after 15 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	2.7942428550535907	[107]	[356,71]	9	hSpCas9	negative selection	1286294
91007013	91007036	15	-	26627737	RPE1	viability after 15 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-3.253070721690414	[602]	[23,11]	-9	hSpCas9	negative selection	1286295
91009828	91009851	15	-	26627737	RPE1	viability after 15 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.17472512163454412	[885]	[372,195]	1	hSpCas9	negative selection	1286296
91022156	91022179	15	+	26627737	RPE1	viability after 15 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.07548011810103994	[431]	[169,88]	0	hSpCas9	negative selection	1286297
91005685	91005708	15	+	26627737	RPE1	viability after 18 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	2.6706273420431086	[8]	[28,0]	9	hSpCas9	negative selection	1368607
91006377	91006400	15	-	26627737	RPE1	viability after 18 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.0605318896066922	[301]	[67,88]	0	hSpCas9	negative selection	1368608
91006647	91006670	15	+	26627737	RPE1	viability after 18 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	1.7624788693808466	[107]	[80,117]	8	hSpCas9	negative selection	1368609
91007013	91007036	15	-	26627737	RPE1	viability after 18 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-5.505202696285455	[602]	[5,0]	-9	hSpCas9	negative selection	1368610
91009828	91009851	15	-	26627737	RPE1	viability after 18 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.07638208897137172	[885]	[225,279]	0	hSpCas9	negative selection	1368611
91022156	91022179	15	+	26627737	RPE1	viability after 18 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.7046363662682219	[431]	[291,80]	4	hSpCas9	negative selection	1368612
91005685	91005708	15	+	26627737	HeLa	viability after 8 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	0.44743079124664753	[54]	[53,6,40]	4	hSpCas9	negative selection	1450922
91006377	91006400	15	-	26627737	HeLa	viability after 8 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	3.149086486747087	[17]	[98,76,40]	9	hSpCas9	negative selection	1450923
91006647	91006670	15	+	26627737	HeLa	viability after 8 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.78926200340745	[510]	[151,78,157]	-7	hSpCas9	negative selection	1450924
91007013	91007036	15	-	26627737	HeLa	viability after 8 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.22530765250455498	[382]	[197,189,57]	-2	hSpCas9	negative selection	1450925
91009828	91009851	15	-	26627737	HeLa	viability after 8 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.8141045528785954	[213]	[222,143,138]	6	hSpCas9	negative selection	1450926
91022156	91022179	15	+	26627737	HeLa	viability after 8 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.5122910779863293	[379]	[148,103,102]	-5	hSpCas9	negative selection	1450927
91005685	91005708	15	+	26627737	HeLa	viability after 12 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.8498762712847889	[54]	[24,4,8]	-6	hSpCas9	negative selection	1533237
91006377	91006400	15	-	26627737	HeLa	viability after 12 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	3.043552106021858	[17]	[8,46,127]	9	hSpCas9	negative selection	1533238
91006647	91006670	15	+	26627737	HeLa	viability after 12 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.7992149687189679	[510]	[157,65,146]	-6	hSpCas9	negative selection	1533239
91007013	91007036	15	-	26627737	HeLa	viability after 12 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.2536182562431639	[382]	[182,120,96]	-2	hSpCas9	negative selection	1533240
91009828	91009851	15	-	26627737	HeLa	viability after 12 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.2153302074949055	[213]	[154,191,268]	8	hSpCas9	negative selection	1533241
91022156	91022179	15	+	26627737	HeLa	viability after 12 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.3726095018742573	[379]	[93,74,198]	-3	hSpCas9	negative selection	1533242
91005685	91005708	15	+	26627737	HeLa	viability after 15 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.40147161117230556	[54]	[5,27,16]	-3	hSpCas9	negative selection	1615552
91006377	91006400	15	-	26627737	HeLa	viability after 15 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	3.4034775419992735	[17]	[79,57,95]	9	hSpCas9	negative selection	1615553
91006647	91006670	15	+	26627737	HeLa	viability after 15 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.5823922574589026	[510]	[81,190,144]	-5	hSpCas9	negative selection	1615554
91007013	91007036	15	-	26627737	HeLa	viability after 15 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-1.3140382802408594	[382]	[69,91,22]	-8	hSpCas9	negative selection	1615555
91009828	91009851	15	-	26627737	HeLa	viability after 15 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.1414195700466858	[213]	[276,135,159]	7	hSpCas9	negative selection	1615556
91022156	91022179	15	+	26627737	HeLa	viability after 15 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.3731974076027165	[379]	[17,49,115]	-8	hSpCas9	negative selection	1615557
91005685	91005708	15	+	26627737	HeLa	viability after 18 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.4267882049332692	[54]	[1,24,16]	-4	hSpCas9	negative selection	1697867
91006377	91006400	15	-	26627737	HeLa	viability after 18 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	3.480781301437032	[17]	[61,47,95]	9	hSpCas9	negative selection	1697868
91006647	91006670	15	+	26627737	HeLa	viability after 18 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.6003425891057506	[510]	[50,158,144]	-5	hSpCas9	negative selection	1697869
91007013	91007036	15	-	26627737	HeLa	viability after 18 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-1.400685337687377	[382]	[39,75,22]	-8	hSpCas9	negative selection	1697870
91009828	91009851	15	-	26627737	HeLa	viability after 18 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.1369853109147752	[213]	[181,115,159]	7	hSpCas9	negative selection	1697871
91022156	91022179	15	+	26627737	HeLa	viability after 18 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.4134777232159275	[379]	[9,39,115]	-8	hSpCas9	negative selection	1697872
91005685	91005708	15	+	26627737	HCT116	viability after 6 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-1.4640503867196988	[84]	[9,1]	-7	hSpCas9	negative selection	1780182
91006377	91006400	15	-	26627737	HCT116	viability after 6 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.10859567519710622	[353]	[88,30]	0	hSpCas9	negative selection	1780183
91006647	91006670	15	+	26627737	HCT116	viability after 6 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.9191999517169248	[502]	[84,17]	-5	hSpCas9	negative selection	1780184
91007013	91007036	15	-	26627737	HCT116	viability after 6 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-2.224240523089562	[828]	[14,34]	-8	hSpCas9	negative selection	1780185
91009828	91009851	15	-	26627737	HCT116	viability after 6 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	-1.0561952180557994	[766]	[144,9]	-6	hSpCas9	negative selection	1780186
91022156	91022179	15	+	26627737	HCT116	viability after 6 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.16658156856171882	[541]	[189,12]	-1	hSpCas9	negative selection	1780187
91005685	91005708	15	+	26627737	HCT116	viability after 8 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.270312283025435	[76]	[19,27,56]	-3	hSpCas9	negative selection	1862497
91006377	91006400	15	-	26627737	HCT116	viability after 8 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.731130592038292	[102]	[93,124,63]	7	hSpCas9	negative selection	1862498
91006647	91006670	15	+	26627737	HCT116	viability after 8 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.2569142635302027	[302]	[151,94,171]	-3	hSpCas9	negative selection	1862499
91007013	91007036	15	-	26627737	HCT116	viability after 8 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	0.19167074080299207	[200]	[144,123,110]	2	hSpCas9	negative selection	1862500
91009828	91009851	15	-	26627737	HCT116	viability after 8 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	-0.037426052473790605	[485]	[385,215,183]	0	hSpCas9	negative selection	1862501
91022156	91022179	15	+	26627737	HCT116	viability after 8 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.1674652593001481	[286]	[147,86,186]	-2	hSpCas9	negative selection	1862502
91005685	91005708	15	+	26627737	HCT116	viability after 9 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-1.4995353696124174	[84]	[2,11]	-8	hSpCas9	negative selection	1944812
91006377	91006400	15	-	26627737	HCT116	viability after 9 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.8229719486292706	[353]	[34,67]	-5	hSpCas9	negative selection	1944813
91006647	91006670	15	+	26627737	HCT116	viability after 9 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	1.0762434978636564	[502]	[204,344]	7	hSpCas9	negative selection	1944814
91007013	91007036	15	-	26627737	HCT116	viability after 9 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-2.518901644675415	[828]	[46,31]	-9	hSpCas9	negative selection	1944815
91009828	91009851	15	-	26627737	HCT116	viability after 9 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	-1.1712984512011442	[766]	[81,97]	-7	hSpCas9	negative selection	1944816
91022156	91022179	15	+	26627737	HCT116	viability after 9 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	0.14444389697458423	[541]	[331,23]	1	hSpCas9	negative selection	1944817
91005685	91005708	15	+	26627737	HCT116	viability after 12 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.8792485564143784	[76]	[14,37,13]	-7	hSpCas9	negative selection	2027127
91006377	91006400	15	-	26627737	HCT116	viability after 12 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.2150521392110027	[102]	[67,164,149]	8	hSpCas9	negative selection	2027128
91006647	91006670	15	+	26627737	HCT116	viability after 12 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.4161681623233852	[302]	[122,173,61]	-4	hSpCas9	negative selection	2027129
91007013	91007036	15	-	26627737	HCT116	viability after 12 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	0.06226287942739528	[200]	[71,141,120]	0	hSpCas9	negative selection	2027130
91009828	91009851	15	-	26627737	HCT116	viability after 12 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.11296059889377186	[485]	[301,343,181]	1	hSpCas9	negative selection	2027131
91022156	91022179	15	+	26627737	HCT116	viability after 12 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.0666689932596571	[286]	[111,50,48]	-8	hSpCas9	negative selection	2027132
91005685	91005708	15	+	26627737	HCT116	viability after 15 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.7808481746139957	[76]	[15,31,27]	-7	hSpCas9	negative selection	2109442
91006377	91006400	15	-	26627737	HCT116	viability after 15 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.7847836062330321	[102]	[129,64,113]	6	hSpCas9	negative selection	2109443
91006647	91006670	15	+	26627737	HCT116	viability after 15 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.3964564490604466	[302]	[58,221,106]	-4	hSpCas9	negative selection	2109444
91007013	91007036	15	-	26627737	HCT116	viability after 15 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.06479634764989972	[200]	[163,94,78]	0	hSpCas9	negative selection	2109445
91009828	91009851	15	-	26627737	HCT116	viability after 15 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	-0.12535176404018467	[485]	[282,236,250]	-1	hSpCas9	negative selection	2109446
91022156	91022179	15	+	26627737	HCT116	viability after 15 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.6283987104803584	[286]	[228,18,86]	-6	hSpCas9	negative selection	2109447
91005685	91005708	15	+	26627737	HCT116	viability after 18 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.44662500847692344	[76]	[11,15,55]	-4	hSpCas9	negative selection	2191757
91006377	91006400	15	-	26627737	HCT116	viability after 18 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.9198221150855705	[102]	[151,32,101]	7	hSpCas9	negative selection	2191758
91006647	91006670	15	+	26627737	HCT116	viability after 18 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.5985114163544549	[302]	[93,116,76]	-5	hSpCas9	negative selection	2191759
91007013	91007036	15	-	26627737	HCT116	viability after 18 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.8909706576653503	[200]	[65,39,51]	-7	hSpCas9	negative selection	2191760
91009828	91009851	15	-	26627737	HCT116	viability after 18 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	-0.28178708038185407	[485]	[236,147,197]	-3	hSpCas9	negative selection	2191761
91022156	91022179	15	+	26627737	HCT116	viability after 18 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.1613240360542791	[286]	[69,33,84]	-8	hSpCas9	negative selection	2191762
91013406	91013429	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCAACAGTGTTGGGAGGTGCAG	VPS33B	ENSG00000184056	0.6842948511225877	[42,2]	[12,1]	3	dCas9-VP64	positive selection	2393108
91020753	91020776	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAACTACTGGG	VPS33B	ENSG00000184056	-0.8834461465924942	[182,246]	[29,20]	-5	dCas9-VP64	positive selection	2476796
91013406	91013429	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCAACAGTGTTGGGAGGTGCAG	VPS33B	ENSG00000184056	1.2046716383138463	[404,186]	[66,371]	7	dCas9-VP64	positive selection	2488363
91020753	91020776	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAACTACTGGG	VPS33B	ENSG00000184056	0.6336599384503461	[246,243]	[91,154]	5	dCas9-VP64	positive selection	2572051
91017820	91017843	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	-0.6413123726599692	[3,3]	[3,0]	-7	hSpCas9	positive selection	3031922
91022203	91022226	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	-0.8501094415652233	[4,3]	[1,0]	-8	hSpCas9	positive selection	3031923
91014393	91014416	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.20401142666377298	[4,4]	[4,2]	-3	hSpCas9	positive selection	3031924
91007016	91007039	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	-0.15528621297494702	[4,4]	[1,4]	-2	hSpCas9	positive selection	3031925
91017820	91017843	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	0.27928450432048035	[3,3]	[1,3]	5	hSpCas9	positive selection	3099780
91022203	91022226	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	-0.27578192131112617	[4,4]	[2,1]	-4	hSpCas9	positive selection	3099781
91014393	91014416	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.251678961599711	[4,4]	[3,1]	-4	hSpCas9	positive selection	3099782
91007016	91007039	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	-0.1253857519340658	[4,4]	[2,2]	-2	hSpCas9	positive selection	3099783
91007507	91007530		+	24336571	A375	resistance to PLX after 7 days	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	0.27695054087987314	[5,6]	[8,6]	7	hSpCas9	positive selection	3155101
91014390	91014413		+	24336571	A375	resistance to PLX after 7 days	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.15234356183759493	[14,12]	[14,15]	5	hSpCas9	positive selection	3155102
91007507	91007530		+	24336571	A375	resistance to PLX after 14 days	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	0.0756764794838577	[4,9]	[2,2]	0	hSpCas9	positive selection	3212894
91014390	91014413		+	24336571	A375	resistance to PLX after 14 days	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.7467201747161932	[18,11]	[11,11]	6	hSpCas9	positive selection	3212895
91007507	91007530		+	24336571	A375	viability after 7 days	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	-0.22862005871579905	[7]	[5,6]	-3	hSpCas9	negative selection	3270687
91014390	91014413		+	24336571	A375	viability after 7 days	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.009231897913030265	[13]	[14,12]	0	hSpCas9	negative selection	3270688
91007507	91007530		+	24336571	A375	viability after 14 days	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	-0.01876088882117921	[7]	[4,9]	0	hSpCas9	negative selection	3328480
91014390	91014413		+	24336571	A375	viability after 14 days	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.1563636632652951	[13]	[18,11]	2	hSpCas9	negative selection	3328481
91014390	91014413	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-1.6763644435063987	[488,488]	[0,0]	-9	hSpCas9	positive selection	3400999
91007029	91007052	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.8301366298045043	[271,271]	[0,0]	-5	hSpCas9	positive selection	3401000
91014420	91014443	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	-0.8354309294740174	[272,272]	[0,0]	-5	hSpCas9	positive selection	3401001
91017819	91017842	15	+	26780180	HT29	viability (Avana library 4 designs)	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	-0.644369933087609	[]	[]	-8	hSpCas9	negative selection	3471154
91022202	91022225	15	+	26780180	HT29	viability (Avana library 4 designs)	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	1.80096061150349	[]	[]	7	hSpCas9	negative selection	3471155
91014392	91014415	15	+	26780180	HT29	viability (Avana library 4 designs)	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	1.92568044682619	[]	[]	7	hSpCas9	negative selection	3471156
91007016	91007039	15	-	26780180	HT29	viability (Avana library 4 designs)	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	2.71460877488962	[]	[]	8	hSpCas9	negative selection	3471157
91014392	91014415	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	3.53621481245143	[]	[]	5	hSpCas9	negative selection	3577819
91017819	91017842	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	-1.85477947289026	[]	[]	-2	hSpCas9	negative selection	3577820
91022202	91022225	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	1.34224545295324	[]	[]	2	hSpCas9	negative selection	3577821
91007016	91007039	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	0.631783708395542	[]	[]	0	hSpCas9	negative selection	3577822
91006377	91006400	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.87859052080728	[]	[]	2	hSpCas9	negative selection	3577823
91006679	91006702	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGCCCTCATAAACCACTTGG	VPS33B	ENSG00000184056	0.961938776653062	[]	[]	1	hSpCas9	negative selection	3577824
91014392	91014415	15	+	26780180	A375	viability (Avana lentiGuide)	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.415621395352441	[]	[]	0	hSpCas9	negative selection	3686478
91017819	91017842	15	+	26780180	A375	viability (Avana lentiGuide)	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	-7.28459624082656	[]	[]	-9	hSpCas9	negative selection	3686479
91022202	91022225	15	+	26780180	A375	viability (Avana lentiGuide)	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	9.14325856768764	[]	[]	6	hSpCas9	negative selection	3686480
91007016	91007039	15	-	26780180	A375	viability (Avana lentiGuide)	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	-2.87411072666772	[]	[]	-5	hSpCas9	negative selection	3686481
91006377	91006400	15	-	26780180	A375	viability (Avana lentiGuide)	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.67380151854409	[]	[]	2	hSpCas9	negative selection	3686482
91006679	91006702	15	+	26780180	A375	viability (Avana lentiGuide)	CTAGGCCCTCATAAACCACTTGG	VPS33B	ENSG00000184056	-4.79862133180707	[]	[]	-7	hSpCas9	negative selection	3686483
91014392	91014415	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.1201293685420099	[7]	[7,7]	3	hSpCas9	positive selection	3795085
91017819	91017842	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	0.021753306732650975	[5]	[4,5]	0	hSpCas9	positive selection	3795086
91022202	91022225	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	0.015105766398176686	[4]	[5,3]	0	hSpCas9	positive selection	3795087
91007016	91007039	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	0.14213896143777402	[5]	[6,5]	4	hSpCas9	positive selection	3795088
91006377	91006400	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.21632220506026067	[5]	[6,6]	6	hSpCas9	positive selection	3795089
91006679	91006702	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGCCCTCATAAACCACTTGG	VPS33B	ENSG00000184056	-0.09478109604917045	[5]	[4,4]	-1	hSpCas9	positive selection	3795090
91014392	91014415	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.017605531867328883	[6]	[5,5]	0	hSpCas9	positive selection	3903692
91017819	91017842	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTGGCAATTCGATCCAAAGGG	VPS33B	ENSG00000184056	0.254884963723209	[5]	[5,4]	6	hSpCas9	positive selection	3903693
91022202	91022225	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAAGTCAGGCAGCTCAGGGG	VPS33B	ENSG00000184056	-0.11922972558225714	[5]	[3,5]	-2	hSpCas9	positive selection	3903694
91007016	91007039	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAATTGTGGAGGAACCTGGAGG	VPS33B	ENSG00000184056	0.24076729668872843	[5]	[5,5]	6	hSpCas9	positive selection	3903695
91006377	91006400	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.17503677065289291	[6]	[6,6]	4	hSpCas9	positive selection	3903696
91006679	91006702	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGCCCTCATAAACCACTTGG	VPS33B	ENSG00000184056	0.4358074435195744	[5]	[6,6]	9	hSpCas9	positive selection	3903697
91006961	91006984	15	+	26780180	A375	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	1.46995025979508	[]	[]	8	hSpCas9	negative selection	4011758
91007509	91007532	15	-	26780180	A375	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	-0.216728237166098	[]	[]	-6	hSpCas9	negative selection	4011759
91014420	91014443	15	-	26780180	A375	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.245039096587039	[]	[]	0	hSpCas9	negative selection	4011760
91007479	91007502	15	+	26780180	A375	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.519619109056843	[]	[]	1	hSpCas9	negative selection	4011761
91007029	91007052	15	-	26780180	A375	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	1.03614723690674	[]	[]	5	hSpCas9	negative selection	4011762
91014390	91014413	15	+	26780180	A375	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	1.15012532651501	[]	[]	6	hSpCas9	negative selection	4011763
91006961	91006984	15	+	26780180	HT29	viability (GeCKOv2 library)	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	1.19710372407802	[]	[]	6	hSpCas9	negative selection	4119724
91007509	91007532	15	-	26780180	HT29	viability (GeCKOv2 library)	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	-0.847446892397156	[]	[]	-9	hSpCas9	negative selection	4119725
91014420	91014443	15	-	26780180	HT29	viability (GeCKOv2 library)	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	-0.160346857985321	[]	[]	-4	hSpCas9	negative selection	4119726
91007479	91007502	15	+	26780180	HT29	viability (GeCKOv2 library)	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.556223137072547	[]	[]	1	hSpCas9	negative selection	4119727
91007029	91007052	15	-	26780180	HT29	viability (GeCKOv2 library)	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	1.29225428979592	[]	[]	6	hSpCas9	negative selection	4119728
91014390	91014413	15	+	26780180	HT29	viability (GeCKOv2 library)	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	1.03858347438529	[]	[]	5	hSpCas9	negative selection	4119729
91007507	91007530	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	-0.029495847289279398	[2]	[1,1]	0	hSpCas9	positive selection	4181853
91014390	91014413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.0663226331945534	[4]	[2,3]	1	hSpCas9	positive selection	4181854
91007507	91007530	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCATAGAGAGTGCTGAGAAGG	VPS33B	ENSG00000184056	-0.2458885758229466	[3]	[0,0,1,0]	-4	hSpCas9	positive selection	4245875
91014390	91014413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.43584689656128833	[4]	[1,2,0,0]	-6	hSpCas9	positive selection	4245876
91007479	91007502	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.3560809190870218	[3]	[3,3]	7	hSpCas9	positive selection	4307384
91006961	91006984	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.015766175582290154	[3]	[3,2]	0	hSpCas9	positive selection	4307385
91007509	91007532	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6651585839617383	[3]	[4,4]	9	hSpCas9	positive selection	4307386
91014390	91014413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.1372322846758129	[3]	[3,2]	2	hSpCas9	positive selection	4371632
91007029	91007052	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.14947458773170283	[3]	[2,1]	-3	hSpCas9	positive selection	4371633
91014420	91014443	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.362825362121008	[3]	[4,3]	7	hSpCas9	positive selection	4371634
91006648	91006670	15	+	27760321	OCIAML3	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.17761572584461832	[579,495]	[397,573]	2	hSpCas9	negative selection	4453416
91006984	91007006	15	-	27760321	OCIAML3	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.4761400598579112	[454,382]	[523,362]	6	hSpCas9	negative selection	4453417
91014393	91014415	15	+	27760321	OCIAML3	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.5502300127700038	[827,510]	[614,935]	6	hSpCas9	negative selection	4453418
91016994	91017016	15	-	27760321	OCIAML3	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-0.2717296140860652	[155,125]	[102,74]	-3	hSpCas9	negative selection	4453419
91017819	91017841	15	+	27760321	OCIAML3	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.5635600201906233	[377,293]	[333,452]	6	hSpCas9	negative selection	4453420
91006648	91006670	15	+	27760321	OCIAML2	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.10786914599157923	[579,495]	[355,463]	-1	hSpCas9	negative selection	4536879
91006984	91007006	15	-	27760321	OCIAML2	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.6734371819337506	[454,382]	[478,616]	8	hSpCas9	negative selection	4536880
91014393	91014415	15	+	27760321	OCIAML2	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.7236202974181968	[827,510]	[746,1054]	8	hSpCas9	negative selection	4536881
91016994	91017016	15	-	27760321	OCIAML2	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	0.6345691586577111	[155,125]	[179,170]	8	hSpCas9	negative selection	4536882
91017819	91017841	15	+	27760321	OCIAML2	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.5993168636775486	[377,293]	[357,475]	7	hSpCas9	negative selection	4536883
91006648	91006670	15	+	27760321	MV411	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.5948729824285504	[579,495]	[456,650]	4	hSpCas9	negative selection	4620342
91006984	91007006	15	-	27760321	MV411	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	1.1821889517428752	[454,382]	[465,863]	8	hSpCas9	negative selection	4620343
91014393	91014415	15	+	27760321	MV411	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.07684614046419291	[827,510]	[517,368]	0	hSpCas9	negative selection	4620344
91016994	91017016	15	-	27760321	MV411	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-1.4968335761149827	[155,125]	[19,51]	-7	hSpCas9	negative selection	4620345
91017819	91017841	15	+	27760321	MV411	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	-0.2967722097746315	[377,293]	[229,102]	-2	hSpCas9	negative selection	4620346
91006648	91006670	15	+	27760321	HL60	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.5734769856840567	[579,495]	[340,244]	-6	hSpCas9	negative selection	4703805
91006984	91007006	15	-	27760321	HL60	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	-0.920725234250688	[454,382]	[150,210]	-7	hSpCas9	negative selection	4703806
91014393	91014415	15	+	27760321	HL60	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.6226754986075796	[827,510]	[347,350]	-6	hSpCas9	negative selection	4703807
91016994	91017016	15	-	27760321	HL60	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-1.2839881204452908	[155,125]	[64,27]	-8	hSpCas9	negative selection	4703808
91017819	91017841	15	+	27760321	HL60	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.8991317047195118	[377,293]	[451,567]	8	hSpCas9	negative selection	4703809
91006648	91006670	15	+	27760321	HT1080	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.06548157810461752	[495,386]	[137,200]	0	hSpCas9	negative selection	4787268
91006984	91007006	15	-	27760321	HT1080	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	1.1708129097577447	[382,298]	[291,320]	6	hSpCas9	negative selection	4787269
91014393	91014415	15	+	27760321	HT1080	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.28622880697982217	[510,398]	[105,346]	1	hSpCas9	negative selection	4787270
91016994	91017016	15	-	27760321	HT1080	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	1.1501373944568645	[125,98]	[67,133]	6	hSpCas9	negative selection	4787271
91017819	91017841	15	+	27760321	HT1080	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	-0.08017209688273913	[293,229]	[124,69]	0	hSpCas9	negative selection	4787272
91006648	91006670	15	+	27760321	HT29	viability after 7 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.13297046154118128	[495,386]	[614,525,427]	-2	hSpCas9	negative selection	4870731
91006984	91007006	15	-	27760321	HT29	viability after 7 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.134085804574192	[382,298]	[695,443,337]	2	hSpCas9	negative selection	4870732
91014393	91014415	15	+	27760321	HT29	viability after 7 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.24309476072050612	[510,398]	[784,727,579]	4	hSpCas9	negative selection	4870733
91016994	91017016	15	-	27760321	HT29	viability after 7 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	0.8663655755088139	[125,98]	[195,341,243]	9	hSpCas9	negative selection	4870734
91017819	91017841	15	+	27760321	HT29	viability after 7 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.12089256287192202	[293,229]	[383,380,336]	1	hSpCas9	negative selection	4870735
91006648	91006670	15	+	27760321	HT29	viability after 25 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.7568673611447305	[495,386]	[287,196,423]	-6	hSpCas9	negative selection	4954194
91006984	91007006	15	-	27760321	HT29	viability after 25 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	-0.053368385480087474	[382,298]	[325,532,257]	0	hSpCas9	negative selection	4954195
91014393	91014415	15	+	27760321	HT29	viability after 25 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.7921090849752497	[510,398]	[424,292,159]	-6	hSpCas9	negative selection	4954196
91016994	91017016	15	-	27760321	HT29	viability after 25 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-1.4961676893232176	[125,98]	[40,15,83]	-7	hSpCas9	negative selection	4954197
91017819	91017841	15	+	27760321	HT29	viability after 25 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.007160161776057383	[293,229]	[292,333,272]	0	hSpCas9	negative selection	4954198
91006648	91006670	15	+	27760321	HT29	viability after 22 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.22147138900459573	[495,386]	[526,432,349]	-2	hSpCas9	negative selection	5037657
91006984	91007006	15	-	27760321	HT29	viability after 22 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	-0.13308741831268656	[382,298]	[413,402,258]	-1	hSpCas9	negative selection	5037658
91014393	91014415	15	+	27760321	HT29	viability after 22 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.4322327747208042	[510,398]	[345,401,422]	-4	hSpCas9	negative selection	5037659
91016994	91017016	15	-	27760321	HT29	viability after 22 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-1.6907274152845886	[125,98]	[38,35,45]	-7	hSpCas9	negative selection	5037660
91017819	91017841	15	+	27760321	HT29	viability after 22 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.20851433243816106	[293,229]	[259,287,505]	2	hSpCas9	negative selection	5037661
91006648	91006670	15	+	27760321	HT29	viability after 19 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.111371869472294	[495,386]	[498,673,240]	-1	hSpCas9	negative selection	5121120
91006984	91007006	15	-	27760321	HT29	viability after 19 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.46753401878167633	[382,298]	[238,592,745]	4	hSpCas9	negative selection	5121121
91014393	91014415	15	+	27760321	HT29	viability after 19 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.5804134765413371	[510,398]	[728,228,133]	-5	hSpCas9	negative selection	5121122
91016994	91017016	15	-	27760321	HT29	viability after 19 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-0.3030762084054579	[125,98]	[109,31,168]	-3	hSpCas9	negative selection	5121123
91017819	91017841	15	+	27760321	HT29	viability after 19 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.2733700806102549	[293,229]	[296,324,453]	2	hSpCas9	negative selection	5121124
91006648	91006670	15	+	27760321	HT29	viability after 16 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.051987305612255674	[495,386]	[433,463,631]	0	hSpCas9	negative selection	5204583
91006984	91007006	15	-	27760321	HT29	viability after 16 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.6235952762925998	[382,298]	[507,579,667]	7	hSpCas9	negative selection	5204584
91014393	91014415	15	+	27760321	HT29	viability after 16 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	-0.05054703573113678	[510,398]	[809,400,295]	0	hSpCas9	negative selection	5204585
91016994	91017016	15	-	27760321	HT29	viability after 16 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-0.017555147026004914	[125,98]	[130,77,165]	0	hSpCas9	negative selection	5204586
91017819	91017841	15	+	27760321	HT29	viability after 16 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.8579808124156574	[293,229]	[541,340,716]	8	hSpCas9	negative selection	5204587
91006648	91006670	15	+	27760321	HT29	viability after 13 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.3622441326358829	[495,386]	[908,604,471]	4	hSpCas9	negative selection	5288046
91006984	91007006	15	-	27760321	HT29	viability after 13 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.2659919517269748	[382,298]	[386,594,446]	3	hSpCas9	negative selection	5288047
91014393	91014415	15	+	27760321	HT29	viability after 13 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.3840537221728559	[510,398]	[965,737,380]	5	hSpCas9	negative selection	5288048
91016994	91017016	15	-	27760321	HT29	viability after 13 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	-0.8560937677222682	[125,98]	[50,85,78]	-7	hSpCas9	negative selection	5288049
91017819	91017841	15	+	27760321	HT29	viability after 13 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.6987509359476548	[293,229]	[411,415,642]	8	hSpCas9	negative selection	5288050
91006648	91006670	15	+	27760321	HT29	viability after 10 days	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.5603490744428112	[495,386]	[367,308,440]	-6	hSpCas9	negative selection	5371509
91006984	91007006	15	-	27760321	HT29	viability after 10 days	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	0.3416163000292975	[382,298]	[312,851,463]	4	hSpCas9	negative selection	5371510
91014393	91014415	15	+	27760321	HT29	viability after 10 days	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.0955197846957263	[510,398]	[712,641,469]	1	hSpCas9	negative selection	5371511
91016994	91017016	15	-	27760321	HT29	viability after 10 days	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	0.4646934162169829	[125,98]	[193,98,283]	6	hSpCas9	negative selection	5371512
91017819	91017841	15	+	27760321	HT29	viability after 10 days	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	0.5127468011089742	[293,229]	[498,305,587]	7	hSpCas9	negative selection	5371513
91006648	91006670	15	+	27760321	MOLM13	viability	TTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	0.7459144280605543	[579,495]	[803,254]	5	hSpCas9	negative selection	5454972
91006984	91007006	15	-	27760321	MOLM13	viability	TGGCGAAACCAAGGGCCGAAGG	VPS33B	ENSG00000184056	-1.0463778168177873	[454,382]	[153,79]	-6	hSpCas9	negative selection	5454973
91014393	91014415	15	+	27760321	MOLM13	viability	ATCGCATATTCTTGATGCGGGG	VPS33B	ENSG00000184056	0.2730751808734635	[827,510]	[353,529]	1	hSpCas9	negative selection	5454974
91016994	91017016	15	-	27760321	MOLM13	viability	GTAGACAAGCTATACAAGGTGG	VPS33B	ENSG00000184056	0.3258495949470739	[155,125]	[143,60]	2	hSpCas9	negative selection	5454975
91017819	91017841	15	+	27760321	MOLM13	viability	CATTGGCAATTCGATCCAAAGG	VPS33B	ENSG00000184056	-1.584730013499596	[377,293]	[65,59]	-7	hSpCas9	negative selection	5454976
91022057	91022080	15	+	27661255	K562	viability	GGCCAAGAACAAGATCAAAGGGG	VPS33B	ENSG00000184056	0.04857350199000343	[608,674]	[523,533]	1	dCas9-KRAB	negative selection	5522285
91022368	91022391	15	-	27661255	K562	viability	GAGGAGCGAGGGCCCATCTGGGG	VPS33B	ENSG00000184056	0.10420757204555976	[547,762]	[572,547]	3	dCas9-KRAB	negative selection	5522286
91022469	91022492	15	-	27661255	K562	viability	GAGGGAGGGTCGAGACACGGTGG	VPS33B	ENSG00000184056	-0.022696034518660743	[827,816]	[708,593]	-1	dCas9-KRAB	negative selection	5522287
91022544	91022567	15	-	27661255	K562	viability	GGGGTTCTCCTCGTACGCTGCGG	VPS33B	ENSG00000184056	-0.004395335067400863	[1118,1302]	[1133,814]	0	dCas9-KRAB	negative selection	5522288
91007479	91007502	15	+	27260156	BXPC3	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.32213853819550453	[786]	[984,972,928,1254]	7	hSpCas9	negative selection	5579844
91006961	91006984	15	+	27260156	BXPC3	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.13191926578708957	[979]	[796,993,863,1110]	-3	hSpCas9	negative selection	5579845
91007509	91007532	15	-	27260156	BXPC3	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.40418604266686475	[743]	[877,947,1102,1228]	8	hSpCas9	negative selection	5579846
91014390	91014413	15	+	27260156	BXPC3	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.06537083334178129	[937]	[822,1068,791,1077]	-1	hSpCas9	negative selection	5644092
91007029	91007052	15	-	27260156	BXPC3	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.19291138111024356	[469]	[350,471,432,471]	-4	hSpCas9	negative selection	5644093
91014420	91014443	15	-	27260156	BXPC3	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.4543669304849727	[759]	[1179,939,1122,1105]	8	hSpCas9	negative selection	5644094
91007479	91007502	15	+	27260156	A673	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.45061423711384585	[786]	[1412,1129,1285,1355]	8	hSpCas9	negative selection	5701095
91006961	91006984	15	+	27260156	A673	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.11848266293833776	[979]	[1250,1013,1055,1030]	-3	hSpCas9	negative selection	5701096
91007509	91007532	15	-	27260156	A673	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6353040243519857	[743]	[1304,1282,1522,1430]	9	hSpCas9	negative selection	5701097
91014390	91014413	15	+	27260156	A673	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.014984590348344873	[937]	[1229,911,1071,1269]	0	hSpCas9	negative selection	5765343
91007029	91007052	15	-	27260156	A673	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.02308068884170449	[469]	[614,469,606,535]	0	hSpCas9	negative selection	5765344
91014420	91014443	15	-	27260156	A673	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.357828286668435	[759]	[1319,1027,1169,1178]	8	hSpCas9	negative selection	5765345
91007479	91007502	15	+	27260156	A375	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5230377748706391	[786]	[1244,1559,1350,1172]	7	hSpCas9	negative selection	5822346
91006961	91006984	15	+	27260156	A375	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.05045478617635868	[979]	[1367,1087,1021,1239]	0	hSpCas9	negative selection	5822347
91007509	91007532	15	-	27260156	A375	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6643417151803971	[743]	[1566,1475,1277,1216]	8	hSpCas9	negative selection	5822348
91014390	91014413	15	+	27260156	A375	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.2401565180121379	[937]	[631,1177,850,1061]	-3	hSpCas9	negative selection	5886594
91007029	91007052	15	-	27260156	A375	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.009066506119798137	[469]	[553,579,493,579]	0	hSpCas9	negative selection	5886595
91014420	91014443	15	-	27260156	A375	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.7035366571682293	[759]	[1407,1632,1616,1176]	9	hSpCas9	negative selection	5886596
91007479	91007502	15	+	27260156	COLO741	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.3354287821062273	[786]	[1593,1157,1091]	7	hSpCas9	negative selection	5943597
91006961	91006984	15	+	27260156	COLO741	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.20728158347800918	[979]	[1040,1432,795]	-4	hSpCas9	negative selection	5943598
91007509	91007532	15	-	27260156	COLO741	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6140731182859881	[743]	[1518,1448,1402]	9	hSpCas9	negative selection	5943599
91014390	91014413	15	+	27260156	COLO741	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.3255652658649455	[937]	[992,1017,865]	-6	hSpCas9	negative selection	6007845
91007029	91007052	15	-	27260156	COLO741	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.017808987498605988	[469]	[525,519,716]	0	hSpCas9	negative selection	6007846
91014420	91014443	15	-	27260156	COLO741	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.18680088401664519	[759]	[1292,1084,961]	4	hSpCas9	negative selection	6007847
91007479	91007502	15	+	27260156	CAL120	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6741338783651613	[786]	[2289,1068,1439]	8	hSpCas9	negative selection	6064848
91006961	91006984	15	+	27260156	CAL120	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.05992445919197387	[979]	[1127,1603,777]	-1	hSpCas9	negative selection	6064849
91007509	91007532	15	-	27260156	CAL120	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.9563990590656185	[743]	[2249,1630,1579]	9	hSpCas9	negative selection	6064850
91014390	91014413	15	+	27260156	CAL120	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.11819763468411415	[937]	[1331,833,1097]	-2	hSpCas9	negative selection	6129096
91007029	91007052	15	-	27260156	CAL120	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.027504294258275816	[469]	[746,645,420]	0	hSpCas9	negative selection	6129097
91014420	91014443	15	-	27260156	CAL120	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.508292303131622	[759]	[1812,1317,980]	7	hSpCas9	negative selection	6129098
91007479	91007502	15	+	27260156	CADOES1	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5007298614890617	[786]	[916,1106,1085,1032]	8	hSpCas9	negative selection	6186099
91006961	91006984	15	+	27260156	CADOES1	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.030816301597825335	[979]	[663,1007,926,1133]	0	hSpCas9	negative selection	6186100
91007509	91007532	15	-	27260156	CADOES1	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7649240872265112	[743]	[1159,1485,935,1119]	9	hSpCas9	negative selection	6186101
91014390	91014413	15	+	27260156	CADOES1	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.2347112980530046	[937]	[748,834,788,586]	-4	hSpCas9	negative selection	6250347
91007029	91007052	15	-	27260156	CADOES1	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.35304039166292445	[469]	[565,577,436,655]	6	hSpCas9	negative selection	6250348
91014420	91014443	15	-	27260156	CADOES1	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.48525769200055247	[759]	[851,1095,878,1136]	7	hSpCas9	negative selection	6250349
91007479	91007502	15	+	27260156	EWS502	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5668760593452523	[786]	[1232,1332,1064,1301]	8	hSpCas9	negative selection	6307350
91006961	91006984	15	+	27260156	EWS502	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.14806009019494681	[979]	[923,755,1219,849]	-3	hSpCas9	negative selection	6307351
91007509	91007532	15	-	27260156	EWS502	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.676431290063812	[743]	[1129,1286,1370,1260]	9	hSpCas9	negative selection	6307352
91014390	91014413	15	+	27260156	EWS502	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.08934273526770942	[937]	[835,904,890,1125]	-2	hSpCas9	negative selection	6371598
91007029	91007052	15	-	27260156	EWS502	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.07780384949736963	[469]	[463,543,555,543]	1	hSpCas9	negative selection	6371599
91014420	91014443	15	-	27260156	EWS502	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.5607353001152657	[759]	[1125,1152,1369,1100]	8	hSpCas9	negative selection	6371600
91007479	91007502	15	+	27260156	EW8	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.3835231893084071	[786]	[1124,844,686,725]	7	hSpCas9	negative selection	6428601
91006961	91006984	15	+	27260156	EW8	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.25128933303052226	[979]	[751,603,613,714]	-5	hSpCas9	negative selection	6428602
91007509	91007532	15	-	27260156	EW8	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.9352255937943389	[743]	[1553,1060,888,1192]	9	hSpCas9	negative selection	6428603
91014390	91014413	15	+	27260156	EW8	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.06151210751722469	[937]	[660,824,648,782]	-1	hSpCas9	negative selection	6492849
91007029	91007052	15	-	27260156	EW8	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.3414468278469866	[469]	[535,421,329,671]	6	hSpCas9	negative selection	6492850
91014420	91014443	15	-	27260156	EW8	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.44914757153373563	[759]	[1101,843,795,655]	7	hSpCas9	negative selection	6492851
91007479	91007502	15	+	27260156	CORL105	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.41388498923048933	[786]	[1418,1125,1337,1052]	7	hSpCas9	negative selection	6549852
91006961	91006984	15	+	27260156	CORL105	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.3236648125668147	[979]	[844,789,1130,933]	-5	hSpCas9	negative selection	6549853
91007509	91007532	15	-	27260156	CORL105	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5931417605223396	[743]	[1560,1026,1456,1246]	9	hSpCas9	negative selection	6549854
91014390	91014413	15	+	27260156	CORL105	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.66220240283585	[937]	[725,580,722,752]	-8	hSpCas9	negative selection	6614100
91007029	91007052	15	-	27260156	CORL105	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.18671004756551035	[469]	[611,354,492,481]	-3	hSpCas9	negative selection	6614101
91014420	91014443	15	-	27260156	CORL105	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.2112068891413691	[759]	[940,985,1105,1095]	4	hSpCas9	negative selection	6614102
91007479	91007502	15	+	27260156	HS294T	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6899824526243353	[786]	[604,510,408,411]	8	hSpCas9	negative selection	6671103
91006961	91006984	15	+	27260156	HS294T	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.08109390667091132	[979]	[250,373,505,300]	-1	hSpCas9	negative selection	6671104
91007509	91007532	15	-	27260156	HS294T	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7230061134053868	[743]	[523,458,372,549]	8	hSpCas9	negative selection	6671105
91014390	91014413	15	+	27260156	HS294T	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.0076984237287519575	[937]	[193,575,347,326]	0	hSpCas9	negative selection	6735351
91007029	91007052	15	-	27260156	HS294T	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.5692695719268861	[469]	[205,363,308,187]	7	hSpCas9	negative selection	6735352
91014420	91014443	15	-	27260156	HS294T	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.0823867345585817	[759]	[257,352,280,363]	1	hSpCas9	negative selection	6735353
91007479	91007502	15	+	27260156	HCC44	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.35148072218509896	[786]	[1130,937,1246,1259]	6	hSpCas9	negative selection	6792354
91006961	91006984	15	+	27260156	HCC44	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.20613905348705452	[979]	[1197,631,1211,906]	-3	hSpCas9	negative selection	6792355
91007509	91007532	15	-	27260156	HCC44	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7066518266075797	[743]	[1392,1411,1556,1154]	9	hSpCas9	negative selection	6792356
91014390	91014413	15	+	27260156	HCC44	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.10257935314250854	[937]	[816,1076,1046,984]	-2	hSpCas9	negative selection	6856602
91007029	91007052	15	-	27260156	HCC44	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.021018397874859346	[469]	[338,572,534,618]	0	hSpCas9	negative selection	6856603
91014420	91014443	15	-	27260156	HCC44	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.42769300763498874	[759]	[1346,1120,1099,1062]	7	hSpCas9	negative selection	6856604
91007479	91007502	15	+	27260156	G402	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6705815219513255	[786]	[1959,2063,1081,1115]	8	hSpCas9	negative selection	6913605
91006961	91006984	15	+	27260156	G402	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.14451115662624303	[979]	[912,1191,988,1204]	-2	hSpCas9	negative selection	6913606
91007509	91007532	15	-	27260156	G402	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7712128703468321	[743]	[1724,1349,1912,1232]	8	hSpCas9	negative selection	6913607
91014390	91014413	15	+	27260156	G402	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.4434087863214895	[937]	[1181,610,716,886]	-5	hSpCas9	negative selection	6977853
91007029	91007052	15	-	27260156	G402	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.24933252792836222	[469]	[695,860,442,733]	3	hSpCas9	negative selection	6977854
91014420	91014443	15	-	27260156	G402	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.6610385485735142	[759]	[1654,1272,1741,1217]	7	hSpCas9	negative selection	6977855
91007479	91007502	15	+	27260156	L33	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.4082883336096569	[786]	[1076,466,554,1075]	8	hSpCas9	negative selection	7034856
91006961	91006984	15	+	27260156	L33	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.17459866614531272	[979]	[841,367,515,911]	-4	hSpCas9	negative selection	7034857
91007509	91007532	15	-	27260156	L33	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5845088215179802	[743]	[1023,460,759,1106]	9	hSpCas9	negative selection	7034858
91014390	91014413	15	+	27260156	L33	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.03147139688287526	[937]	[793,402,594,1112]	0	hSpCas9	negative selection	7099104
91007029	91007052	15	-	27260156	L33	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.04539142125904807	[469]	[547,185,298,460]	1	hSpCas9	negative selection	7099105
91014420	91014443	15	-	27260156	L33	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.22229392402884474	[759]	[1069,297,462,1005]	5	hSpCas9	negative selection	7099106
91007479	91007502	15	+	27260156	K562	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5936866065861891	[786]	[1220,947,1444,652]	7	hSpCas9	negative selection	7156107
91006961	91006984	15	+	27260156	K562	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.1591818057470047	[979]	[747,1197,1201,751]	2	hSpCas9	negative selection	7156108
91007509	91007532	15	-	27260156	K562	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.8210358785617436	[743]	[1587,922,1405,807]	9	hSpCas9	negative selection	7156109
91014390	91014413	15	+	27260156	K562	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.015431499061323128	[937]	[993,865,850,619]	0	hSpCas9	negative selection	7220355
91007029	91007052	15	-	27260156	K562	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.5214913257288533	[469]	[193,320,464,186]	-6	hSpCas9	negative selection	7220356
91014420	91014443	15	-	27260156	K562	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.42995314104253324	[759]	[1038,799,1250,583]	5	hSpCas9	negative selection	7220357
91007479	91007502	15	+	27260156	HT29	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.38710300417130183	[786]	[1338,1195,1494,998]	7	hSpCas9	negative selection	7277358
91006961	91006984	15	+	27260156	HT29	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.1565574789215055	[979]	[1119,1264,931,981]	-3	hSpCas9	negative selection	7277359
91007509	91007532	15	-	27260156	HT29	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5372735653635935	[743]	[1226,1382,1326,1303]	9	hSpCas9	negative selection	7277360
91014390	91014413	15	+	27260156	HT29	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.5486498963793833	[937]	[852,857,590,817]	-7	hSpCas9	negative selection	7341606
91007029	91007052	15	-	27260156	HT29	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.2518148190926392	[469]	[559,506,580,298]	-5	hSpCas9	negative selection	7341607
91014420	91014443	15	-	27260156	HT29	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.3035316715638616	[759]	[1005,1396,1126,1045]	6	hSpCas9	negative selection	7341608
91007479	91007502	15	+	27260156	MHHES1	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6719022335096164	[786]	[1706,1700,1398,976]	9	hSpCas9	negative selection	7398609
91006961	91006984	15	+	27260156	MHHES1	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.0429937748328153	[979]	[1447,1254,900,786]	-1	hSpCas9	negative selection	7398610
91007509	91007532	15	-	27260156	MHHES1	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7324177659559868	[743]	[1560,1388,1313,1310]	9	hSpCas9	negative selection	7398611
91014390	91014413	15	+	27260156	MHHES1	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.054729287205997346	[937]	[1441,1247,810,693]	-1	hSpCas9	negative selection	7462857
91007029	91007052	15	-	27260156	MHHES1	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.26395453835945115	[469]	[706,782,571,516]	5	hSpCas9	negative selection	7462858
91014420	91014443	15	-	27260156	MHHES1	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.42847232939117186	[759]	[1274,1429,1065,909]	7	hSpCas9	negative selection	7462859
91007479	91007502	15	+	27260156	MEWO	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5757643326790528	[786]	[1322,1034,977]	9	hSpCas9	negative selection	7519860
91006961	91006984	15	+	27260156	MEWO	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.27510718252714084	[979]	[1008,664,647]	-5	hSpCas9	negative selection	7519861
91007509	91007532	15	-	27260156	MEWO	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6566983550052811	[743]	[1295,931,1102]	9	hSpCas9	negative selection	7519862
91014390	91014413	15	+	27260156	MEWO	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.027392756067725177	[937]	[1010,658,942]	0	hSpCas9	negative selection	7584108
91007029	91007052	15	-	27260156	MEWO	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.0039052217462398403	[469]	[482,457,382]	0	hSpCas9	negative selection	7584109
91014420	91014443	15	-	27260156	MEWO	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.16431524109376128	[759]	[877,787,739]	3	hSpCas9	negative selection	7584110
91007479	91007502	15	+	27260156	LNCAPCLONEFGC	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.41754937315306895	[786]	[780,821,1146,1098]	6	hSpCas9	negative selection	7641111
91006961	91006984	15	+	27260156	LNCAPCLONEFGC	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.2709428013082752	[979]	[783,552,1034,625]	-4	hSpCas9	negative selection	7641112
91007509	91007532	15	-	27260156	LNCAPCLONEFGC	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.46468343759165565	[743]	[806,817,1108,1021]	7	hSpCas9	negative selection	7641113
91014390	91014413	15	+	27260156	LNCAPCLONEFGC	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.547988089366587	[937]	[475,540,641,678]	-7	hSpCas9	negative selection	7705359
91007029	91007052	15	-	27260156	LNCAPCLONEFGC	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.23212654566037066	[469]	[622,395,550,441]	3	hSpCas9	negative selection	7705360
91014420	91014443	15	-	27260156	LNCAPCLONEFGC	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.41524275425320156	[759]	[1000,835,968,876]	6	hSpCas9	negative selection	7705361
91007479	91007502	15	+	27260156	PANC0327	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6785078321261738	[786]	[1318,1094,1185,894]	8	hSpCas9	negative selection	7762362
91006961	91006984	15	+	27260156	PANC0327	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.12093840886109908	[979]	[939,512,653,1142]	-2	hSpCas9	negative selection	7762363
91007509	91007532	15	-	27260156	PANC0327	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6522260579549944	[743]	[1339,882,943,1031]	8	hSpCas9	negative selection	7762364
91014390	91014413	15	+	27260156	PANC0327	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.2449587634357525	[937]	[614,585,702,915]	-4	hSpCas9	negative selection	7826610
91007029	91007052	15	-	27260156	PANC0327	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.1758541288344774	[469]	[258,284,376,558]	-3	hSpCas9	negative selection	7826611
91014420	91014443	15	-	27260156	PANC0327	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.6407198627674482	[759]	[1023,908,1031,1260]	8	hSpCas9	negative selection	7826612
91007479	91007502	15	+	27260156	NCIH2009	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6436534935191934	[786]	[2065,1352,1806]	8	hSpCas9	negative selection	7883613
91006961	91006984	15	+	27260156	NCIH2009	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.024164662972344653	[979]	[1927,1129,1097]	0	hSpCas9	negative selection	7883614
91007509	91007532	15	-	27260156	NCIH2009	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.8656861793785703	[743]	[2499,1783,1516]	9	hSpCas9	negative selection	7883615
91014390	91014413	15	+	27260156	NCIH2009	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.020224231566495554	[937]	[1096,1681,1049]	0	hSpCas9	negative selection	7947861
91007029	91007052	15	-	27260156	NCIH2009	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.2880603991134845	[469]	[907,745,771]	4	hSpCas9	negative selection	7947862
91014420	91014443	15	-	27260156	NCIH2009	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.41671923314876946	[759]	[1577,1011,1698]	6	hSpCas9	negative selection	7947863
91007479	91007502	15	+	27260156	NCIH1373	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.9839683971367942	[786]	[2247,1124,2158,410]	8	hSpCas9	negative selection	8004864
91006961	91006984	15	+	27260156	NCIH1373	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.6549876203570391	[979]	[2012,1191,2029,465]	6	hSpCas9	negative selection	8004865
91007509	91007532	15	-	27260156	NCIH1373	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.9414335097936798	[743]	[1675,1500,1380,494]	8	hSpCas9	negative selection	8004866
91014390	91014413	15	+	27260156	NCIH1373	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.4315931860328439	[937]	[1030,420,665,287]	-4	hSpCas9	negative selection	8069112
91007029	91007052	15	-	27260156	NCIH1373	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.37268474262111706	[469]	[778,673,726,144]	3	hSpCas9	negative selection	8069113
91014420	91014443	15	-	27260156	NCIH1373	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.7581321428306076	[759]	[1949,1366,1335,308]	7	hSpCas9	negative selection	8069114
91007479	91007502	15	+	27260156	PATU8902	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6929831836789903	[786]	[1649,1827,1250,2577]	7	hSpCas9	negative selection	8126115
91006961	91006984	15	+	27260156	PATU8902	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.20396129321779777	[979]	[676,1505,1047,1590]	-2	hSpCas9	negative selection	8126116
91007509	91007532	15	-	27260156	PATU8902	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.944762563066614	[743]	[2022,1556,1644,2938]	8	hSpCas9	negative selection	8126117
91014390	91014413	15	+	27260156	PATU8902	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.3907132896850658	[937]	[1300,1249,694,780]	-4	hSpCas9	negative selection	8190363
91007029	91007052	15	-	27260156	PATU8902	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.03429961541323605	[469]	[533,898,711,355]	0	hSpCas9	negative selection	8190364
91014420	91014443	15	-	27260156	PATU8902	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.6549345103075566	[759]	[1509,1751,1794,1550]	7	hSpCas9	negative selection	8190365
91007479	91007502	15	+	27260156	PANC1	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.577852867408217	[786]	[870,1152,935,1078]	8	hSpCas9	negative selection	8247366
91006961	91006984	15	+	27260156	PANC1	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.25607057891149587	[979]	[770,1023,581,523]	-4	hSpCas9	negative selection	8247367
91007509	91007532	15	-	27260156	PANC1	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5874565455676556	[743]	[799,1482,859,815]	8	hSpCas9	negative selection	8247368
91014390	91014413	15	+	27260156	PANC1	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.28015135896994947	[937]	[635,665,665,673]	-4	hSpCas9	negative selection	8311614
91007029	91007052	15	-	27260156	PANC1	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.037363773828220065	[469]	[449,506,219,407]	0	hSpCas9	negative selection	8311615
91014420	91014443	15	-	27260156	PANC1	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.3340935935822853	[759]	[638,777,1118,750]	5	hSpCas9	negative selection	8311616
91007479	91007502	15	+	27260156	PANC0813	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.6851444154333876	[786]	[1774,1163,1386,1634]	9	hSpCas9	negative selection	8368617
91006961	91006984	15	+	27260156	PANC0813	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.07351935315259372	[979]	[847,1405,991,1103]	-1	hSpCas9	negative selection	8368618
91007509	91007532	15	-	27260156	PANC0813	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7770835082224813	[743]	[1601,1487,1679,1242]	9	hSpCas9	negative selection	8368619
91014390	91014413	15	+	27260156	PANC0813	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.0968767825405853	[937]	[1100,914,1059,1048]	-1	hSpCas9	negative selection	8432865
91007029	91007052	15	-	27260156	PANC0813	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.27136497355350286	[469]	[422,899,711,609]	4	hSpCas9	negative selection	8432866
91014420	91014443	15	-	27260156	PANC0813	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.48118359643330066	[759]	[1085,1335,1266,1276]	7	hSpCas9	negative selection	8432867
91007479	91007502	15	+	27260156	RDES	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5383796285550372	[786]	[1165,1145,1389,1610]	8	hSpCas9	negative selection	8489868
91006961	91006984	15	+	27260156	RDES	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.11064600503203814	[979]	[969,1159,1301,1504]	1	hSpCas9	negative selection	8489869
91007509	91007532	15	-	27260156	RDES	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.8028406399796287	[743]	[1123,1679,1438,1786]	9	hSpCas9	negative selection	8489870
91014390	91014413	15	+	27260156	RDES	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.46682383309034037	[937]	[680,650,722,1127]	-7	hSpCas9	negative selection	8554116
91007029	91007052	15	-	27260156	RDES	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.014030809885823437	[469]	[504,592,479,544]	0	hSpCas9	negative selection	8554117
91014420	91014443	15	-	27260156	RDES	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.6185628832801251	[759]	[1216,1081,1391,1750]	8	hSpCas9	negative selection	8554118
91007479	91007502	15	+	27260156	PC3	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.4499021244495912	[786]	[672,886,1505,1488]	8	hSpCas9	negative selection	8611119
91006961	91006984	15	+	27260156	PC3	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.06666627130630787	[979]	[526,1144,1256,1011]	-1	hSpCas9	negative selection	8611120
91007509	91007532	15	-	27260156	PC3	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5176117363548437	[743]	[844,918,1358,1220]	9	hSpCas9	negative selection	8611121
91014390	91014413	15	+	27260156	PC3	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.037321519460570274	[937]	[682,1047,1342,715]	-1	hSpCas9	negative selection	8675367
91007029	91007052	15	-	27260156	PC3	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.014809346140100212	[469]	[348,390,795,489]	0	hSpCas9	negative selection	8675368
91014420	91014443	15	-	27260156	PC3	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.24251717753708069	[759]	[588,942,1185,1024]	5	hSpCas9	negative selection	8675369
91007479	91007502	15	+	27260156	PATU8988T	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5255625843450725	[786]	[1395,1251,836,895]	8	hSpCas9	negative selection	8732370
91006961	91006984	15	+	27260156	PATU8988T	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.23938872184347149	[979]	[806,616,796,984]	-4	hSpCas9	negative selection	8732371
91007509	91007532	15	-	27260156	PATU8988T	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.46508442722111976	[743]	[1030,1051,893,999]	7	hSpCas9	negative selection	8732372
91014390	91014413	15	+	27260156	PATU8988T	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	0.04839709582878737	[937]	[1048,1054,966,666]	0	hSpCas9	negative selection	8796618
91007029	91007052	15	-	27260156	PATU8988T	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.010027595953708763	[469]	[369,711,292,455]	0	hSpCas9	negative selection	8796619
91014420	91014443	15	-	27260156	PATU8988T	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.21010714134350705	[759]	[861,949,695,905]	3	hSpCas9	negative selection	8796620
91007479	91007502	15	+	27260156	T47D	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.4628185593562796	[786]	[1401,1079,1256,1333]	8	hSpCas9	negative selection	8853621
91006961	91006984	15	+	27260156	T47D	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.03982380335626168	[979]	[1060,999,1151,1241]	-1	hSpCas9	negative selection	8853622
91007509	91007532	15	-	27260156	T47D	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5849828660540349	[743]	[1426,1249,1231,1296]	9	hSpCas9	negative selection	8853623
91014390	91014413	15	+	27260156	T47D	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.10305306767012323	[937]	[1018,850,1113,1100]	-2	hSpCas9	negative selection	8917869
91007029	91007052	15	-	27260156	T47D	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.06399545309420118	[469]	[603,541,511,432]	-1	hSpCas9	negative selection	8917870
91014420	91014443	15	-	27260156	T47D	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.2824357741535459	[759]	[1121,1134,986,1058]	6	hSpCas9	negative selection	8917871
91007479	91007502	15	+	27260156	SU8686	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.7236623494302413	[786]	[1284,1039,1272,1634]	9	hSpCas9	negative selection	8974872
91006961	91006984	15	+	27260156	SU8686	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	0.07628322715722291	[979]	[851,861,1111,1361]	1	hSpCas9	negative selection	8974873
91007509	91007532	15	-	27260156	SU8686	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.8488946821463631	[743]	[1238,1335,1267,1495]	9	hSpCas9	negative selection	8974874
91014390	91014413	15	+	27260156	SU8686	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.00605198438982768	[937]	[943,685,1000,1130]	0	hSpCas9	negative selection	9039120
91007029	91007052	15	-	27260156	SU8686	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.49296385063343084	[469]	[565,661,734,668]	8	hSpCas9	negative selection	9039121
91014420	91014443	15	-	27260156	SU8686	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.46584890311378846	[759]	[959,685,1109,1536]	7	hSpCas9	negative selection	9039122
91007479	91007502	15	+	27260156	SKES1	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.42741172308934805	[786]	[1310,1189,908,876]	8	hSpCas9	negative selection	9096123
91006961	91006984	15	+	27260156	SKES1	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.3000498228109273	[979]	[921,768,764,733]	-6	hSpCas9	negative selection	9096124
91007509	91007532	15	-	27260156	SKES1	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.7088284859977138	[743]	[1527,1194,1027,1140]	9	hSpCas9	negative selection	9096125
91014390	91014413	15	+	27260156	SKES1	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.07245065237594961	[937]	[1008,1027,750,806]	-1	hSpCas9	negative selection	9160371
91007029	91007052	15	-	27260156	SKES1	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.0709410538738385	[469]	[436,642,421,316]	-1	hSpCas9	negative selection	9160372
91014420	91014443	15	-	27260156	SKES1	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.40817730067713565	[759]	[1149,969,1159,774]	8	hSpCas9	negative selection	9160373
91007479	91007502	15	+	27260156	TOV112D	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.32345873049670526	[786]	[836,1256,1109,798]	6	hSpCas9	negative selection	9217374
91006961	91006984	15	+	27260156	TOV112D	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.10088308764732656	[979]	[884,1178,895,765]	-2	hSpCas9	negative selection	9217375
91007509	91007532	15	-	27260156	TOV112D	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6923685047620735	[743]	[1080,1105,1208,1378]	9	hSpCas9	negative selection	9217376
91014390	91014413	15	+	27260156	TOV112D	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.05784749176695836	[937]	[784,1201,839,846]	-1	hSpCas9	negative selection	9281622
91007029	91007052	15	-	27260156	TOV112D	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.13790507041799466	[469]	[579,396,354,384]	-3	hSpCas9	negative selection	9281623
91014420	91014443	15	-	27260156	TOV112D	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.22260089043358167	[759]	[1012,996,780,799]	4	hSpCas9	negative selection	9281624
91007479	91007502	15	+	27260156	TC71	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.3823218051193834	[786]	[1139,1124,910,1235]	8	hSpCas9	negative selection	9338625
91006961	91006984	15	+	27260156	TC71	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.10486587334990394	[979]	[1004,952,890,1065]	-3	hSpCas9	negative selection	9338626
91007509	91007532	15	-	27260156	TC71	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.5229361714298705	[743]	[1127,1033,1151,1277]	9	hSpCas9	negative selection	9338627
91014390	91014413	15	+	27260156	TC71	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.17451666181379755	[937]	[720,891,907,1055]	-4	hSpCas9	negative selection	9402873
91007029	91007052	15	-	27260156	TC71	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	0.020624698091979737	[469]	[453,562,539,485]	0	hSpCas9	negative selection	9402874
91014420	91014443	15	-	27260156	TC71	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.3519079192512975	[759]	[1158,1003,964,1029]	8	hSpCas9	negative selection	9402875
91007479	91007502	15	+	27260156	TC32	viability	CTGCCAATTCCATAGCAGTTTGG	VPS33B	ENSG00000184056	0.5876479651911007	[786]	[1119,785,1386,1264]	8	hSpCas9	negative selection	9459876
91006961	91006984	15	+	27260156	TC32	viability	AGAAAGATATGTCCAATCTCTGG	VPS33B	ENSG00000184056	-0.020814226034928218	[979]	[979,750,1013,895]	0	hSpCas9	negative selection	9459877
91007509	91007532	15	-	27260156	TC32	viability	CACCTTCTCAGCACTCTCTATGG	VPS33B	ENSG00000184056	0.6072838815638549	[743]	[1124,655,1331,1291]	8	hSpCas9	negative selection	9459878
91014390	91014413	15	+	27260156	TC32	viability	TGTATCGCATATTCTTGATGCGG	VPS33B	ENSG00000184056	-0.18111705082425067	[937]	[671,545,1060,945]	-3	hSpCas9	negative selection	9524124
91007029	91007052	15	-	27260156	TC32	viability	GGCAGATGGCATATGAATTGTGG	VPS33B	ENSG00000184056	-0.021747655769335125	[469]	[378,410,508,442]	0	hSpCas9	negative selection	9524125
91014420	91014443	15	-	27260156	TC32	viability	CTCTCATAGATTGTGCTTCTTGG	VPS33B	ENSG00000184056	0.5388971926491264	[759]	[980,842,1409,995]	8	hSpCas9	negative selection	9524126
91005685	91005708	15	+	27869803	HPAFII	viability after 27 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-1.9418354358141523	[94]	[6,17,NaN]	-8	hSpCas9	negative selection	9555408
91006377	91006400	15	-	27869803	HPAFII	viability after 27 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.204330143372175	[137]	[212,128,NaN]	8	hSpCas9	negative selection	9555409
91006647	91006670	15	+	27869803	HPAFII	viability after 27 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-1.1861917014885315	[204]	[48,45,NaN]	-7	hSpCas9	negative selection	9555410
91007013	91007036	15	-	27869803	HPAFII	viability after 27 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-2.374570372071504	[190]	[38,2,NaN]	-8	hSpCas9	negative selection	9555411
91009828	91009851	15	-	27869803	HPAFII	viability after 27 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.0098581385056786	[236]	[215,279,NaN]	8	hSpCas9	negative selection	9555412
91022156	91022179	15	+	27869803	HPAFII	viability after 27 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.4493890040696207	[288]	[29,76,NaN]	-7	hSpCas9	negative selection	9555413
91005685	91005708	15	+	27869803	HPAFII	viability after 15 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.8116361331682238	[94]	[88,38,NaN]	-7	hSpCas9	negative selection	9637857
91006377	91006400	15	-	27869803	HPAFII	viability after 15 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.105033723951682	[137]	[421,254,NaN]	9	hSpCas9	negative selection	9637858
91006647	91006670	15	+	27869803	HPAFII	viability after 15 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.21366585362405877	[204]	[271,138,NaN]	-2	hSpCas9	negative selection	9637859
91007013	91007036	15	-	27869803	HPAFII	viability after 15 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-1.0816742248165	[190]	[141,68,NaN]	-8	hSpCas9	negative selection	9637860
91009828	91009851	15	-	27869803	HPAFII	viability after 15 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.8100271620964193	[236]	[662,311,NaN]	8	hSpCas9	negative selection	9637861
91022156	91022179	15	+	27869803	HPAFII	viability after 15 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-1.3852393247016874	[288]	[166,88,NaN]	-8	hSpCas9	negative selection	9637862
91005685	91005708	15	+	27869803	ASPC1	viability after 36 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-1.887296011865822	[162]	[0,45,0]	-9	hSpCas9	negative selection	9720306
91006377	91006400	15	-	27869803	ASPC1	viability after 36 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.8699888092196012	[370]	[65,68,74]	-7	hSpCas9	negative selection	9720307
91006647	91006670	15	+	27869803	ASPC1	viability after 36 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	1.2044019509390778	[414]	[408,292,309]	9	hSpCas9	negative selection	9720308
91007013	91007036	15	-	27869803	ASPC1	viability after 36 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	0.7115936060768907	[352]	[509,25,122]	7	hSpCas9	negative selection	9720309
91009828	91009851	15	-	27869803	ASPC1	viability after 36 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.314791659063729	[648]	[317,207,311]	3	hSpCas9	negative selection	9720310
91022156	91022179	15	+	27869803	ASPC1	viability after 36 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.8596705287027013	[510]	[209,9,88]	-7	hSpCas9	negative selection	9720311
91005685	91005708	15	+	27869803	PATU8988S	viability after 35 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-2.2233965178528696	[150]	[22,2,NaN]	-9	hSpCas9	negative selection	9802755
91006377	91006400	15	-	27869803	PATU8988S	viability after 35 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.25667442158777143	[312]	[111,98,NaN]	-3	hSpCas9	negative selection	9802756
91006647	91006670	15	+	27869803	PATU8988S	viability after 35 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.6345336106507482	[400]	[117,89,NaN]	-6	hSpCas9	negative selection	9802757
91007013	91007036	15	-	27869803	PATU8988S	viability after 35 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.4164370935359696	[324]	[130,64,NaN]	-4	hSpCas9	negative selection	9802758
91009828	91009851	15	-	27869803	PATU8988S	viability after 35 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.00085517853897496	[500]	[156,246,NaN]	0	hSpCas9	negative selection	9802759
91022156	91022179	15	+	27869803	PATU8988S	viability after 35 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.5675464375727372	[352]	[65,125,NaN]	-5	hSpCas9	negative selection	9802760
91005685	91005708	15	+	27869803	PATU8988S	viability after 31 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-1.7909973538699315	[150]	[12,22,NaN]	-9	hSpCas9	negative selection	9885204
91006377	91006400	15	-	27869803	PATU8988S	viability after 31 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.5967855117264013	[312]	[142,246,NaN]	7	hSpCas9	negative selection	9885205
91006647	91006670	15	+	27869803	PATU8988S	viability after 31 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.5705026129498807	[400]	[64,161,NaN]	-6	hSpCas9	negative selection	9885206
91007013	91007036	15	-	27869803	PATU8988S	viability after 31 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-0.5848844547197904	[324]	[81,91,NaN]	-6	hSpCas9	negative selection	9885207
91009828	91009851	15	-	27869803	PATU8988S	viability after 31 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	0.24336535561068373	[500]	[228,245,NaN]	3	hSpCas9	negative selection	9885208
91022156	91022179	15	+	27869803	PATU8988S	viability after 31 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-0.23464446532717576	[352]	[61,192,NaN]	-3	hSpCas9	negative selection	9885209
91005685	91005708	15	+	27869803	HPAFII	viability after 35 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-0.903649087953555	[94]	[28,21,NaN]	-5	hSpCas9	negative selection	9967653
91006377	91006400	15	-	27869803	HPAFII	viability after 35 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.892506434647837	[137]	[100,161,NaN]	6	hSpCas9	negative selection	9967654
91006647	91006670	15	+	27869803	HPAFII	viability after 35 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-1.3441575317196923	[204]	[30,51,NaN]	-6	hSpCas9	negative selection	9967655
91007013	91007036	15	-	27869803	HPAFII	viability after 35 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-1.7603509225377305	[190]	[52,0,NaN]	-7	hSpCas9	negative selection	9967656
91009828	91009851	15	-	27869803	HPAFII	viability after 35 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.0151274528417358	[236]	[162,331,NaN]	7	hSpCas9	negative selection	9967657
91022156	91022179	15	+	27869803	HPAFII	viability after 35 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-2.2859465338954856	[288]	[29,29,NaN]	-8	hSpCas9	negative selection	9967658
91005685	91005708	15	+	27869803	HPAFII	viability after 31 days	GAAACCTACGGAGACTCAGCAGG	VPS33B	ENSG00000184056	-3.439502670898559	[94]	[2,6,NaN]	-9	hSpCas9	negative selection	10050102
91006377	91006400	15	-	27869803	HPAFII	viability after 31 days	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	1.5678704562371883	[137]	[231,226,NaN]	9	hSpCas9	negative selection	10050103
91006647	91006670	15	+	27869803	HPAFII	viability after 31 days	CTTACCACACTTGATGCGGAAGG	VPS33B	ENSG00000184056	-0.6907123824147633	[204]	[110,27,NaN]	-4	hSpCas9	negative selection	10050104
91007013	91007036	15	-	27869803	HPAFII	viability after 31 days	ATTGTGGAGGAACCTGGAGGAGG	VPS33B	ENSG00000184056	-2.9330270481594884	[190]	[25,0,NaN]	-8	hSpCas9	negative selection	10050105
91009828	91009851	15	-	27869803	HPAFII	viability after 31 days	TCAGTTCTATGCGTGTGAGATGG	VPS33B	ENSG00000184056	1.1068753985084638	[236]	[229,347,NaN]	7	hSpCas9	negative selection	10050106
91022156	91022179	15	+	27869803	HPAFII	viability after 31 days	GCTCCAGCAGATAGATGAGCTGG	VPS33B	ENSG00000184056	-2.1015127973630485	[288]	[21,54,NaN]	-8	hSpCas9	negative selection	10050107
91007007	91007030	15	-	28162770	P31FUJ	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	0.7241290736937351	[50]	[98]	8	hSpCas9	negative selection	10263766
91002092	91002115	15	+	28162770	P31FUJ	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.49302283214662723	[597]	[988]	5	hSpCas9	negative selection	10263767
91006377	91006400	15	-	28162770	P31FUJ	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.022698528734007684	[159]	[190]	0	hSpCas9	negative selection	10263768
91017793	91017816	15	+	28162770	P31FUJ	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	-0.67337479580036	[113]	[83]	-5	hSpCas9	negative selection	10263769
91006991	91007014	15	-	28162770	P31FUJ	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.13803549095393017	[173]	[224]	1	hSpCas9	negative selection	10263770
91004869	91004892	15	+	28162770	P31FUJ	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.17735307348471915	[221]	[294]	1	hSpCas9	negative selection	10263771
91000527	91000550	15	-	28162770	P31FUJ	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.12474980020370507	[159]	[204]	1	hSpCas9	negative selection	10263772
91009800	91009823	15	-	28162770	P31FUJ	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.49143814635065564	[523]	[437]	-4	hSpCas9	negative selection	10263773
91005072	91005095	15	-	28162770	P31FUJ	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.06640889394231941	[408]	[458]	0	hSpCas9	negative selection	10263774
91004892	91004915	15	+	28162770	P31FUJ	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.1866320229814526	[245]	[253]	-2	hSpCas9	negative selection	10263775
91007007	91007030	15	-	28162770	TF1	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10433132
91002092	91002115	15	+	28162770	TF1	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	NaN	[NaN]	[607]	1	hSpCas9	negative selection	10433133
91006377	91006400	15	-	28162770	TF1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10433134
91017793	91017816	15	+	28162770	TF1	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10433135
91006991	91007014	15	-	28162770	TF1	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10433136
91004869	91004892	15	+	28162770	TF1	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10433137
91000527	91000550	15	-	28162770	TF1	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10433138
91009800	91009823	15	-	28162770	TF1	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10433139
91005072	91005095	15	-	28162770	TF1	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10433140
91004892	91004915	15	+	28162770	TF1	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10433141
91007007	91007030	15	-	28162770	SKM1	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-2.1439297929093675	[14]	[5]	-8	hSpCas9	negative selection	10602498
91002092	91002115	15	+	28162770	SKM1	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	-0.22185279348617326	[125]	[190]	-2	hSpCas9	negative selection	10602499
91006377	91006400	15	-	28162770	SKM1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.004865755171815922	[41]	[73]	0	hSpCas9	negative selection	10602500
91017793	91017816	15	+	28162770	SKM1	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	-0.25906550363084824	[43]	[64]	-2	hSpCas9	negative selection	10602501
91006991	91007014	15	-	28162770	SKM1	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	-0.44696226667508077	[63]	[82]	-4	hSpCas9	negative selection	10602502
91004869	91004892	15	+	28162770	SKM1	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.01544528919203468	[60]	[108]	0	hSpCas9	negative selection	10602503
91000527	91000550	15	-	28162770	SKM1	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.2279940576978423	[52]	[79]	-2	hSpCas9	negative selection	10602504
91009800	91009823	15	-	28162770	SKM1	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.42926286585193596	[162]	[213]	-4	hSpCas9	negative selection	10602505
91005072	91005095	15	-	28162770	SKM1	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.5493812433590137	[124]	[150]	-4	hSpCas9	negative selection	10602506
91004892	91004915	15	+	28162770	SKM1	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.1147834472498514	[48]	[79]	-1	hSpCas9	negative selection	10602507
91007007	91007030	15	-	28162770	SKM1	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-2.1439297929093675	[14]	[5]	-8	hSpCas9	negative selection	10771864
91002092	91002115	15	+	28162770	SKM1	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	-0.22185279348617326	[125]	[190]	-2	hSpCas9	negative selection	10771865
91006377	91006400	15	-	28162770	SKM1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.004865755171815922	[41]	[73]	0	hSpCas9	negative selection	10771866
91017793	91017816	15	+	28162770	SKM1	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	-0.25906550363084824	[43]	[64]	-2	hSpCas9	negative selection	10771867
91006991	91007014	15	-	28162770	SKM1	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	-0.44696226667508077	[63]	[82]	-4	hSpCas9	negative selection	10771868
91004869	91004892	15	+	28162770	SKM1	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.01544528919203468	[60]	[108]	0	hSpCas9	negative selection	10771869
91000527	91000550	15	-	28162770	SKM1	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.2279940576978423	[52]	[79]	-2	hSpCas9	negative selection	10771870
91009800	91009823	15	-	28162770	SKM1	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.42926286585193596	[162]	[213]	-4	hSpCas9	negative selection	10771871
91005072	91005095	15	-	28162770	SKM1	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.5493812433590137	[124]	[150]	-4	hSpCas9	negative selection	10771872
91004892	91004915	15	+	28162770	SKM1	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.1147834472498514	[48]	[79]	-1	hSpCas9	negative selection	10771873
91007007	91007030	15	-	28162770	PL21	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	1.422532035825768	[35]	[41]	9	hSpCas9	negative selection	10941230
91002092	91002115	15	+	28162770	PL21	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.4120141639117688	[353]	[204]	3	hSpCas9	negative selection	10941231
91006377	91006400	15	-	28162770	PL21	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.2981112530385052	[225]	[79]	-2	hSpCas9	negative selection	10941232
91017793	91017816	15	+	28162770	PL21	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.7046121973501085	[85]	[60]	6	hSpCas9	negative selection	10941233
91006991	91007014	15	-	28162770	PL21	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.41164371968303193	[227]	[131]	3	hSpCas9	negative selection	10941234
91004869	91004892	15	+	28162770	PL21	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	-0.22870368431455423	[209]	[77]	-2	hSpCas9	negative selection	10941235
91000527	91000550	15	-	28162770	PL21	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.7147127873190783	[118]	[84]	6	hSpCas9	negative selection	10941236
91009800	91009823	15	-	28162770	PL21	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.7137037417609653	[519]	[137]	-5	hSpCas9	negative selection	10941237
91005072	91005095	15	-	28162770	PL21	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.2542774177962809	[358]	[130]	-2	hSpCas9	negative selection	10941238
91004892	91004915	15	+	28162770	PL21	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.5864567474014867	[137]	[39]	-4	hSpCas9	negative selection	10941239
91007007	91007030	15	-	28162770	P31FUJ	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	0.7241290736937351	[50]	[98]	8	hSpCas9	negative selection	11110596
91002092	91002115	15	+	28162770	P31FUJ	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.49302283214662723	[597]	[988]	5	hSpCas9	negative selection	11110597
91006377	91006400	15	-	28162770	P31FUJ	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.022698528734007684	[159]	[190]	0	hSpCas9	negative selection	11110598
91017793	91017816	15	+	28162770	P31FUJ	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	-0.67337479580036	[113]	[83]	-5	hSpCas9	negative selection	11110599
91006991	91007014	15	-	28162770	P31FUJ	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.13803549095393017	[173]	[224]	1	hSpCas9	negative selection	11110600
91004869	91004892	15	+	28162770	P31FUJ	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.17735307348471915	[221]	[294]	1	hSpCas9	negative selection	11110601
91000527	91000550	15	-	28162770	P31FUJ	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.12474980020370507	[159]	[204]	1	hSpCas9	negative selection	11110602
91009800	91009823	15	-	28162770	P31FUJ	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.49143814635065564	[523]	[437]	-4	hSpCas9	negative selection	11110603
91005072	91005095	15	-	28162770	P31FUJ	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.06640889394231941	[408]	[458]	0	hSpCas9	negative selection	11110604
91004892	91004915	15	+	28162770	P31FUJ	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.1866320229814526	[245]	[253]	-2	hSpCas9	negative selection	11110605
91007007	91007030	15	-	28162770	OCIAML5	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-1.0585174483314232	[29]	[25]	-6	hSpCas9	negative selection	11279962
91002092	91002115	15	+	28162770	OCIAML5	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.44216979015431734	[262]	[644]	4	hSpCas9	negative selection	11279963
91006377	91006400	15	-	28162770	OCIAML5	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.28304561401186235	[90]	[134]	-2	hSpCas9	negative selection	11279964
91017793	91017816	15	+	28162770	OCIAML5	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.6073650477733001	[27]	[76]	5	hSpCas9	negative selection	11279965
91006991	91007014	15	-	28162770	OCIAML5	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.9038287518370602	[105]	[357]	7	hSpCas9	negative selection	11279966
91004869	91004892	15	+	28162770	OCIAML5	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	-0.9134671155281404	[143]	[137]	-5	hSpCas9	negative selection	11279967
91000527	91000550	15	-	28162770	OCIAML5	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.2671040701428408	[115]	[173]	-2	hSpCas9	negative selection	11279968
91009800	91009823	15	-	28162770	OCIAML5	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	0.4836453394564648	[249]	[630]	4	hSpCas9	negative selection	11279969
91005072	91005095	15	-	28162770	OCIAML5	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.789239733408558	[336]	[351]	-5	hSpCas9	negative selection	11279970
91004892	91004915	15	+	28162770	OCIAML5	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.5876509346318427	[173]	[208]	-4	hSpCas9	negative selection	11279971
91007007	91007030	15	-	28162770	EOL1	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-2.0589641056408965	[86]	[10]	-8	hSpCas9	negative selection	11449328
91002092	91002115	15	+	28162770	EOL1	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.769442410201574	[568]	[510]	6	hSpCas9	negative selection	11449329
91006377	91006400	15	-	28162770	EOL1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.1377365066838081	[354]	[169]	-1	hSpCas9	negative selection	11449330
91017793	91017816	15	+	28162770	EOL1	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	-0.6500355833706225	[276]	[92]	-5	hSpCas9	negative selection	11449331
91006991	91007014	15	-	28162770	EOL1	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	-0.3016562637159325	[378]	[161]	-2	hSpCas9	negative selection	11449332
91004869	91004892	15	+	28162770	EOL1	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.4965943844064053	[373]	[277]	4	hSpCas9	negative selection	11449333
91000527	91000550	15	-	28162770	EOL1	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.05665130757787962	[145]	[79]	0	hSpCas9	negative selection	11449334
91009800	91009823	15	-	28162770	EOL1	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.8874836376965425	[617]	[175]	-6	hSpCas9	negative selection	11449335
91005072	91005095	15	-	28162770	EOL1	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.7404960528096846	[462]	[145]	-5	hSpCas9	negative selection	11449336
91004892	91004915	15	+	28162770	EOL1	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	1.109659176827523	[167]	[190]	8	hSpCas9	negative selection	11449337
91007007	91007030	15	-	28162770	MOLM13	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-5.97505411430415	[86]	[0]	-9	hSpCas9	negative selection	11618694
91002092	91002115	15	+	28162770	MOLM13	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.4929367995862646	[570]	[580]	3	hSpCas9	negative selection	11618695
91006377	91006400	15	-	28162770	MOLM13	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.12542050821638012	[335]	[264]	0	hSpCas9	negative selection	11618696
91017793	91017816	15	+	28162770	MOLM13	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.3001619358065124	[163]	[145]	2	hSpCas9	negative selection	11618697
91006991	91007014	15	-	28162770	MOLM13	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.7645063879027536	[367]	[451]	6	hSpCas9	negative selection	11618698
91004869	91004892	15	+	28162770	MOLM13	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.5093093089245596	[308]	[317]	4	hSpCas9	negative selection	11618699
91000527	91000550	15	-	28162770	MOLM13	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	0.2935592009822652	[245]	[217]	2	hSpCas9	negative selection	11618700
91009800	91009823	15	-	28162770	MOLM13	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.7525573954768996	[740]	[317]	-4	hSpCas9	negative selection	11618701
91005072	91005095	15	-	28162770	MOLM13	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-1.0983539218299883	[535]	[180]	-5	hSpCas9	negative selection	11618702
91004892	91004915	15	+	28162770	MOLM13	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	1.3423584994607198	[197]	[362]	8	hSpCas9	negative selection	11618703
91007007	91007030	15	-	28162770	HEL	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	0.057776331279200566	[47]	[31]	0	hSpCas9	negative selection	11788060
91002092	91002115	15	+	28162770	HEL	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.6358851609592943	[421]	[419]	5	hSpCas9	negative selection	11788061
91006377	91006400	15	-	28162770	HEL	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.2405649432905456	[272]	[147]	-2	hSpCas9	negative selection	11788062
91017793	91017816	15	+	28162770	HEL	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.74343283161983	[165]	[177]	6	hSpCas9	negative selection	11788063
91006991	91007014	15	-	28162770	HEL	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.527261614580421	[337]	[311]	4	hSpCas9	negative selection	11788064
91004869	91004892	15	+	28162770	HEL	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.17976685565781125	[305]	[221]	1	hSpCas9	negative selection	11788065
91000527	91000550	15	-	28162770	HEL	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.28600248482982116	[157]	[82]	-2	hSpCas9	negative selection	11788066
91009800	91009823	15	-	28162770	HEL	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	0.28063078465831326	[445]	[346]	2	hSpCas9	negative selection	11788067
91005072	91005095	15	-	28162770	HEL	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.4434178117493577	[413]	[194]	-3	hSpCas9	negative selection	11788068
91004892	91004915	15	+	28162770	HEL	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-1.4053554562006882	[243]	[58]	-7	hSpCas9	negative selection	11788069
91007007	91007030	15	-	28162770	MV411	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	0.7526728590331975	[30]	[43]	6	hSpCas9	negative selection	11957426
91002092	91002115	15	+	28162770	MV411	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.5860619345424514	[377]	[477]	5	hSpCas9	negative selection	11957427
91006377	91006400	15	-	28162770	MV411	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.3295086837218085	[204]	[216]	3	hSpCas9	negative selection	11957428
91017793	91017816	15	+	28162770	MV411	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.02504512944632742	[97]	[83]	0	hSpCas9	negative selection	11957429
91006991	91007014	15	-	28162770	MV411	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.01703755084496128	[270]	[230]	0	hSpCas9	negative selection	11957430
91004869	91004892	15	+	28162770	MV411	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.533527192844235	[268]	[327]	5	hSpCas9	negative selection	11957431
91000527	91000550	15	-	28162770	MV411	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.18806405105578416	[141]	[104]	-1	hSpCas9	negative selection	11957432
91009800	91009823	15	-	28162770	MV411	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.01491165197905997	[420]	[350]	0	hSpCas9	negative selection	11957433
91005072	91005095	15	-	28162770	MV411	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	0.17647102942863158	[374]	[356]	1	hSpCas9	negative selection	11957434
91004892	91004915	15	+	28162770	MV411	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.17003304709716865	[133]	[126]	1	hSpCas9	negative selection	11957435
91007007	91007030	15	-	28162770	MONOMAC1	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-0.7413573632833641	[34]	[23]	-6	hSpCas9	negative selection	12126792
91002092	91002115	15	+	28162770	MONOMAC1	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.4479216183635122	[313]	[490]	4	hSpCas9	negative selection	12126793
91006377	91006400	15	-	28162770	MONOMAC1	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.36886731784591786	[126]	[187]	3	hSpCas9	negative selection	12126794
91017793	91017816	15	+	28162770	MONOMAC1	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.35045094824293965	[64]	[94]	3	hSpCas9	negative selection	12126795
91006991	91007014	15	-	28162770	MONOMAC1	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.23906226774711975	[152]	[206]	2	hSpCas9	negative selection	12126796
91004869	91004892	15	+	28162770	MONOMAC1	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.2903148570351803	[106]	[149]	3	hSpCas9	negative selection	12126797
91000527	91000550	15	-	28162770	MONOMAC1	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	1.6843186564418273	[75]	[279]	9	hSpCas9	negative selection	12126798
91009800	91009823	15	-	28162770	MONOMAC1	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	0.15885716746933287	[360]	[461]	1	hSpCas9	negative selection	12126799
91005072	91005095	15	-	28162770	MONOMAC1	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	0.2977278446900241	[219]	[309]	3	hSpCas9	negative selection	12126800
91004892	91004915	15	+	28162770	MONOMAC1	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.4566384037456168	[81]	[128]	4	hSpCas9	negative selection	12126801
91007007	91007030	15	-	28162770	OCIAML2	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-0.6792164470535789	[12]	[44]	-5	hSpCas9	negative selection	12296158
91002092	91002115	15	+	28162770	OCIAML2	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.07862861379731623	[74]	[438]	0	hSpCas9	negative selection	12296159
91006377	91006400	15	-	28162770	OCIAML2	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	-0.06381283276828581	[32]	[174]	0	hSpCas9	negative selection	12296160
91017793	91017816	15	+	28162770	OCIAML2	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	0.7971424995982958	[18]	[182]	7	hSpCas9	negative selection	12296161
91006991	91007014	15	-	28162770	OCIAML2	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.4038392926739799	[29]	[219]	4	hSpCas9	negative selection	12296162
91004869	91004892	15	+	28162770	OCIAML2	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	0.694572765957748	[33]	[304]	6	hSpCas9	negative selection	12296163
91000527	91000550	15	-	28162770	OCIAML2	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.32767187140011833	[23]	[105]	-3	hSpCas9	negative selection	12296164
91009800	91009823	15	-	28162770	OCIAML2	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	-0.49058443161780607	[90]	[358]	-4	hSpCas9	negative selection	12296165
91005072	91005095	15	-	28162770	OCIAML2	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	-0.54573128048288	[68]	[261]	-4	hSpCas9	negative selection	12296166
91004892	91004915	15	+	28162770	OCIAML2	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	-0.002480989503754971	[29]	[165]	0	hSpCas9	negative selection	12296167
91007007	91007030	15	-	28162770	OCIAML3	viability	GAGGAACCTGGAGGAGGAGGAGG	VPS33B	ENSG00000184056	-0.44961773098898816	[18]	[41]	-3	hSpCas9	negative selection	12465524
91002092	91002115	15	+	28162770	OCIAML3	viability	CGGCTGTGAGGGTGTCCCCGGGG	VPS33B	ENSG00000184056	0.4292621389986837	[122]	[499]	4	hSpCas9	negative selection	12465525
91006377	91006400	15	-	28162770	OCIAML3	viability	GAAGGTGCTACTCAATGCCGAGG	VPS33B	ENSG00000184056	0.23759482798011825	[58]	[209]	2	hSpCas9	negative selection	12465526
91017793	91017816	15	+	28162770	OCIAML3	viability	AAGGGACAGTACCTTCAGGATGG	VPS33B	ENSG00000184056	1.4894083678634742	[20]	[177]	9	hSpCas9	negative selection	12465527
91006991	91007014	15	-	28162770	OCIAML3	viability	GAGGAGGATGGCGAAACCAAGGG	VPS33B	ENSG00000184056	0.32026248564995297	[51]	[195]	3	hSpCas9	negative selection	12465528
91004869	91004892	15	+	28162770	OCIAML3	viability	GGGCTCACCATTCTCAGTGATGG	VPS33B	ENSG00000184056	-1.257724252459731	[79]	[100]	-7	hSpCas9	negative selection	12465529
91000527	91000550	15	-	28162770	OCIAML3	viability	GACATGGCTTACGTCTTCGGTGG	VPS33B	ENSG00000184056	-0.038488917495488995	[32]	[96]	0	hSpCas9	negative selection	12465530
91009800	91009823	15	-	28162770	OCIAML3	viability	GAGGAAGAGGGAATCTATGGAGG	VPS33B	ENSG00000184056	0.6562189892090105	[131]	[627]	6	hSpCas9	negative selection	12465531
91005072	91005095	15	-	28162770	OCIAML3	viability	GGAGAGCACCAGCTACATTGAGG	VPS33B	ENSG00000184056	0.006221617050303441	[93]	[284]	0	hSpCas9	negative selection	12465532
91004892	91004915	15	+	28162770	OCIAML3	viability	ACAAAAGGCACATGAGGCGCAGG	VPS33B	ENSG00000184056	0.4377012194031748	[44]	[183]	4	hSpCas9	negative selection	12465533